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Search of human proteins with 4505011
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
(774 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens] 1652 0.0
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens] 907 0.0
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens] 874 0.0
gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 267 2e-71
gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 263 5e-70
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 257 3e-68
gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 257 3e-68
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 256 6e-68
gi|18152779 scavenger receptor cysteine rich domain containing, ... 225 1e-58
gi|20149540 lysyl oxidase preproprotein [Homo sapiens] 221 3e-57
gi|67782346 lysyl oxidase-like 1 preproprotein [Homo sapiens] 216 6e-56
gi|44889963 CD163 antigen isoform b [Homo sapiens] 213 5e-55
gi|44662834 CD163 antigen isoform a [Homo sapiens] 213 5e-55
gi|4506143 neurotrypsin precursor [Homo sapiens] 211 2e-54
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H... 206 5e-53
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 173 5e-43
gi|5174411 CD5 molecule-like [Homo sapiens] 161 2e-39
gi|239752563 PREDICTED: hypothetical protein [Homo sapiens] 156 8e-38
gi|194018748 CD6 molecule [Homo sapiens] 130 4e-30
gi|5031863 galectin 3 binding protein [Homo sapiens] 112 1e-24
gi|5803080 macrophage receptor with collagenous structure [Homo ... 107 5e-23
gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo... 106 7e-23
gi|47271477 scavenger receptor class A, member 5 [Homo sapiens] 101 3e-21
gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens] 98 3e-20
gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo... 51 5e-06
gi|119392081 complement factor I preproprotein [Homo sapiens] 43 0.001
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 35 0.20
gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo sap... 35 0.20
gi|166197668 CD5 molecule [Homo sapiens] 34 0.59
gi|223942069 enterokinase precursor [Homo sapiens] 33 1.0
>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
Length = 774
Score = 1652 bits (4277), Expect = 0.0
Identities = 774/774 (100%), Positives = 774/774 (100%)
Query: 1 MERPLCSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRL 60
MERPLCSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRL
Sbjct: 1 MERPLCSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRL 60
Query: 61 AGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGP 120
AGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGP
Sbjct: 61 AGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGP 120
Query: 121 IWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLN 180
IWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLN
Sbjct: 121 IWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLN 180
Query: 181 IQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGER 240
IQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGER
Sbjct: 181 IQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGER 240
Query: 241 TYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVS 300
TYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVS
Sbjct: 241 TYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVS 300
Query: 301 CVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSA 360
CVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSA
Sbjct: 301 CVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSA 360
Query: 361 SVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDA 420
SVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDA
Sbjct: 361 SVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDA 420
Query: 421 GVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQL 480
GVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQL
Sbjct: 421 GVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQL 480
Query: 481 GLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAG 540
GLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAG
Sbjct: 481 GLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAG 540
Query: 541 VACSETAPDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTGYRRLLRFS 600
VACSETAPDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTGYRRLLRFS
Sbjct: 541 VACSETAPDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTGYRRLLRFS 600
Query: 601 SQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTKVAEGHKASFCLED 660
SQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTKVAEGHKASFCLED
Sbjct: 601 SQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTKVAEGHKASFCLED 660
Query: 661 TECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEV 720
TECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEV
Sbjct: 661 TECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEV 720
Query: 721 AESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ 774
AESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ
Sbjct: 721 AESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ 774
>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
Length = 753
Score = 907 bits (2344), Expect = 0.0
Identities = 413/727 (56%), Positives = 539/727 (74%), Gaps = 9/727 (1%)
Query: 47 PQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAK 106
P+ A ++ RLAG RK EGRVE+ G+WGT+CDDDF++ AAH++CRELG+ EA
Sbjct: 33 PEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEAT 92
Query: 107 SWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGF 166
WT S+ YG G G IWLDNL C+G E ++ C S GWG +DC H ED GV+C D+R+PGF
Sbjct: 93 GWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGF 152
Query: 167 KFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKN 226
N + ++E+ ++QVE++RIR + R+ PV EG VEV+ W Q+CDK W+A N
Sbjct: 153 SDSNVI--EVEH-HLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHN 209
Query: 227 SRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPM 286
S VVCGM GFP E+ N Y++ A R++ + + C GTEAH+S C L + D
Sbjct: 210 SHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTA 269
Query: 287 KNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPE-QPLVRLRGGAYIGEGRVEVLKNG 345
+ C G PAVVSCVPG V++ + ++ KP+ + VRL+GGA+ GEGRVEVLK
Sbjct: 270 R---CPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKAS 326
Query: 346 EWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDC 405
WGTVCD KWDL +ASVVCRELGFGSA+EA++G+R+GQG+G IHL+E++C+G E S+ C
Sbjct: 327 TWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKC 386
Query: 406 KF-NAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVC 464
N ++ C+H +DAGVRCN P G + ++RL+GGR+ +EGRVEV + G L WG++C
Sbjct: 387 PHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLIC 446
Query: 465 GQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHD 524
G +WG +EAMV CRQLGLG+A++ QETWYW N +VVMSGV+C+GTELSL C H
Sbjct: 447 GDDWGTLEAMVACRQLGLGYANHGLQETWYWDSG-NITEVVMSGVRCTGTELSLDQCAHH 505
Query: 525 GEDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASA 584
G + C + G ++ AGV CSETA DL+L++ +VQ+T Y+EDRP+ ML CA EENCL++SA
Sbjct: 506 GTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSA 565
Query: 585 AQTDPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLN 644
+ G+RRLLRFSSQIHN G++DFRPK GRH+W+WH+CH HYHSM++FTHYD+L N
Sbjct: 566 RSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPN 625
Query: 645 GTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVP 704
GTKVAEGHKASFCLEDTEC+ D+ K YECANFG+QGIT+GCWD+YRHDIDCQW+DITDV
Sbjct: 626 GTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVK 685
Query: 705 PGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFS 764
PG+Y+ QVVINPNFEVAESD++NN MKC +YDGHRIW++NCHIG +FSEE ++FE +
Sbjct: 686 PGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYP 745
Query: 765 GLLNNQL 771
G +NQ+
Sbjct: 746 GQTSNQI 752
>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
Length = 756
Score = 874 bits (2259), Expect = 0.0
Identities = 407/740 (55%), Positives = 527/740 (71%), Gaps = 23/740 (3%)
Query: 47 PQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAK 106
P P ++ +LRL G + K EGR+EV + GQWGTVCDD+F+I A V CR+LG+ A
Sbjct: 21 PSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAAL 80
Query: 107 SWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGF 166
+W S+ YG+GEGPIWLDN+ C G E++L C SNGWGV+DC H+EDVGV+C +R G+
Sbjct: 81 TWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGY 140
Query: 167 KFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKN 226
++ N + ++E++R++ IL++ ++ +PV EG VEVK W+Q+CD+ WT N
Sbjct: 141 -LSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNN 199
Query: 227 SRVVCGMFGFPGERTYNTKVYK-------------MFASRRKQRYWPFSMDCTGTEAHIS 273
SRVVCGM GFP E ++ Y+ + + K +W + C GTE H++
Sbjct: 200 SRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMA 259
Query: 274 SCKLGPQVSLDPMKNV---TCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRG 330
+C QV + P + C G+ AVVSCV G F P RK E+P VRLR
Sbjct: 260 NC----QVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRS 315
Query: 331 GAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHL 390
GA +GEGRVEVL N +WGTVCD +W+L+SASVVCR+LGFGSA+EA+ G+RLGQG+GPIHL
Sbjct: 316 GAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHL 375
Query: 391 NEIQCTGNEKSIIDCKFNAESQ-GCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVE 449
+E++C G E+++ DC SQ GC HE DA VRCN P MG Q ++RL GGR P EG +E
Sbjct: 376 SEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLE 435
Query: 450 VLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGV 509
V VE NG WG VC +NWG+ EAMV CRQLGLGFA +A++ETW+W G + +VVMSGV
Sbjct: 436 VQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGV 495
Query: 510 KCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMF 569
+CSGTEL+L C+ G V C GG ++ AGV+C ++APDLV+NA++VQ+T YLEDRP+
Sbjct: 496 RCSGTELALQQCQRHGP-VHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLS 554
Query: 570 MLQCAMEENCLSASAAQTDPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHY 629
L CA EENCLS SA D GYRRLLRFS+QI+N G++DFRPK GR +W+WH CHRHY
Sbjct: 555 QLYCAHEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHY 614
Query: 630 HSMEVFTHYDLLNLNGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMY 689
HS+EVFTHYDLL LNG+KVAEGHKASFCLEDT C +Q+ Y CANFG+QG+T+GCWD Y
Sbjct: 615 HSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTY 674
Query: 690 RHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIG 749
RHDIDCQWVDITDV PG+Y+FQV++NP++EVAESD+SNN+++CR +YDGHR+W++NCH G
Sbjct: 675 RHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTG 734
Query: 750 GSFSEETEKKFEHFSGLLNN 769
S+ E E L NN
Sbjct: 735 NSYPANAELSLEQEQRLRNN 754
>gi|148539842 deleted in malignant brain tumors 1 isoform b
precursor [Homo sapiens]
Length = 2413
Score = 267 bits (683), Expect = 2e-71
Identities = 188/556 (33%), Positives = 263/556 (47%), Gaps = 61/556 (10%)
Query: 6 CSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKR 65
C H + + P S + +SWP P P + + + LRL
Sbjct: 191 CGHGEDAGVICSAAQPQSTLRPESWP---VRISPPVP------TEGSESSLALRLVNGGD 241
Query: 66 KHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDN 125
+ GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD+
Sbjct: 242 R-CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
Query: 126 LHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVED 185
+ C+G+E+ L +C NGW +C H+ED GV+CS + ++ +
Sbjct: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360
Query: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGE 239
+ +R + R +G VEV +W +CD W ++ VVC G PG
Sbjct: 361 LALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGN 415
Query: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296
+R Q P +D C+G E+++ SC +S + C++
Sbjct: 416 ------------ARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN------CQHSED 457
Query: 297 AVVSCVPGQVFSPDGPSRFRKAYKPEQPL-------VRLRGGAYIGEGRVEVLKNGEWGT 349
A V C +S P P + +RL G +GRVEVL G WGT
Sbjct: 458 AGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 517
Query: 350 VCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA 409
VCDD WD A+VVCR+LG G A A +R GQG GPI L++++C+GNE + C N
Sbjct: 518 VCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNG 577
Query: 410 -ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNW 468
S C H EDAGV C+ P L LRL G + +GRVEVL + WG VC +W
Sbjct: 578 WLSHNCGHSEDAGVICSGPESSL--ALRLVNGGDRCQGRVEVLYRGS----WGTVCDDSW 631
Query: 469 GIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDV 528
+A VVCRQLG G+A++A + G S +V+ V+CSG E L C ++G
Sbjct: 632 DTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPNNG--W 686
Query: 529 ACPQGGVQYGAGVACS 544
G AGV CS
Sbjct: 687 LSHNCGHHEDAGVICS 702
Score = 256 bits (655), Expect = 4e-68
Identities = 184/514 (35%), Positives = 253/514 (49%), Gaps = 70/514 (13%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 612 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 671
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSL--INQIENLNIQVEDI 186
+G+E+ L +C +NGW +C H ED GV+CS + ++L I + +
Sbjct: 672 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL 731
Query: 187 RIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGER 240
+R + + R +G VEV +W +CD W ++ VVC G PG
Sbjct: 732 TLRLVNGSDR-----CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN- 785
Query: 241 TYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPA 297
+R Q P +D C+G E+++ SC +S + C + A
Sbjct: 786 -----------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHHEDA 828
Query: 298 VVSCVPGQ---VFSPD-GPSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVCD 352
V C Q SPD P+ PE L +RL G +GRVEVL G WGTVCD
Sbjct: 829 GVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 888
Query: 353 DKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ES 411
D WD A+VVCR+LG G A A +R GQG GPI L++++C+G E + C N S
Sbjct: 889 DSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLS 948
Query: 412 QGCNHEEDAGVRC------NTPA-------------MGLQKK--LRLNGGRNPYEGRVEV 450
C H EDAGV C +TP+ +G + LRL G + +GRVEV
Sbjct: 949 HNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEV 1008
Query: 451 LVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVK 510
L + + WG VC +W +A VVCRQLG G+A +A + G S +V+ V+
Sbjct: 1009 LYQGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVR 1061
Query: 511 CSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
CSG E L C H+G G AGV CS
Sbjct: 1062 CSGHESYLWSCPHNG--WLSHNCGHSEDAGVICS 1093
Score = 255 bits (651), Expect = 1e-67
Identities = 179/510 (35%), Positives = 245/510 (48%), Gaps = 66/510 (12%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 1003 QGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 1062
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188
+G+E+ L +C NGW +C H+ED GV+CS + ++ + + +
Sbjct: 1063 SGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLAL 1122
Query: 189 RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGERTY 242
R + R +G VEV +W +CD +W ++ VVC G PG
Sbjct: 1123 RLVNGGDR-----CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN--- 1174
Query: 243 NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299
+R Q P +D C+G E+++ SC +S + C + A V
Sbjct: 1175 ---------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHHEDAGV 1219
Query: 300 SCVPGQ---VFSPD-GPSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354
C Q SPD P+ E L +RL G +GRVEVL G WGTVCDD
Sbjct: 1220 ICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDY 1279
Query: 355 WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQG 413
WD A+VVCR+LG G A A +R GQG GPI L++++C+G+E + C N S
Sbjct: 1280 WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 1339
Query: 414 CNHEEDAGVRC-------------------NTPAMGLQKKLRLNGGRNPYEGRVEVLVER 454
C H EDAGV C +T LRL G + +GRVEVL
Sbjct: 1340 CGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRG 1399
Query: 455 NGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGT 514
+ WG VC W +A VVCRQLG G+A++A + G S +V+ V+CSG
Sbjct: 1400 S----WGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGH 1452
Query: 515 ELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
E L C H+G G AGV CS
Sbjct: 1453 ESYLWSCPHNG--WLSHNCGHHEDAGVICS 1480
Score = 254 bits (649), Expect = 2e-67
Identities = 178/514 (34%), Positives = 242/514 (47%), Gaps = 68/514 (13%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 1261 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1320
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188
+G+E+ L +C NGW +C H ED GV+CS + ++ + + +
Sbjct: 1321 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL 1380
Query: 189 RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGERTY 242
R + R +G VEV +W +CD +W ++ VVC G PG +
Sbjct: 1381 RLVNGGDR-----CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF 1435
Query: 243 NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299
Q P +D C+G E+++ SC +S + C + A V
Sbjct: 1436 G------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHHEDAGV 1477
Query: 300 SCVPGQVFSPDGP-----SRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354
C Q P SR A +RL G GRVEVL G WGTVCDD
Sbjct: 1478 ICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDY 1537
Query: 355 WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAE-SQG 413
WD A+VVCR+LG G A A ++ GQG GPI L++++C+G+E + C N S
Sbjct: 1538 WDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 1597
Query: 414 CNHEEDAGVRC-----------------NTPAMGLQKK----LRLNGGRNPYEGRVEVLV 452
C H EDAGV C N PA+ + + LRL G + GRVEVL
Sbjct: 1598 CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLY 1657
Query: 453 ERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCS 512
+ WG VC +W +A VVCRQLG G+A +A + G S +V+ V+CS
Sbjct: 1658 RGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCS 1710
Query: 513 GTELSLAHCRHDGEDVACPQGGVQYGAGVACSET 546
G E L C H G G AGV CS T
Sbjct: 1711 GNESYLWSCPHKG--WLTHNCGHHEDAGVICSAT 1742
Score = 252 bits (643), Expect = 1e-66
Identities = 184/523 (35%), Positives = 249/523 (47%), Gaps = 71/523 (13%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVE+ Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 112 QGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRC 171
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIEN---LNIQVED 185
+G+E+ L +C NGW +C H ED GV+CS + S +I
Sbjct: 172 SGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESS 231
Query: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGE 239
+ +R + R R G VEV +W +CD +W ++ VVC G PG
Sbjct: 232 LALRLVNGGDRCR-----GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
Query: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296
+ Q P +D C+G E+++ SC ++ + C +
Sbjct: 287 AQFG------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHN------CGHSED 328
Query: 297 AVVSCVPGQ---VFSPDG-PSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVC 351
A V C Q SPD P+ PE L +RL G +GRVEVL G WGTVC
Sbjct: 329 AGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388
Query: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-E 410
DD WD A+VVCR+LG G A A +R GQG GPI L++++C+G E + C N
Sbjct: 389 DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448
Query: 411 SQGCNHEEDAGVRC------NTPA-------------MGLQKK--LRLNGGRNPYEGRVE 449
S C H EDAGV C +TP+ +G + LRL G + +GRVE
Sbjct: 449 SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508
Query: 450 VLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGV 509
VL + WG VC +W +A VVCRQLG G+A A + G S +V+ V
Sbjct: 509 VLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG---SGPIVLDDV 561
Query: 510 KCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPDLVL 552
+CSG E L C H+G G AGV CS L L
Sbjct: 562 RCSGNESYLWSCPHNG--WLSHNCGHSEDAGVICSGPESSLAL 602
Score = 251 bits (640), Expect = 2e-66
Identities = 178/513 (34%), Positives = 245/513 (47%), Gaps = 89/513 (17%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 373 QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 432
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVC---------SDKRIPGFKFDNSLINQIENL 179
+G E+ L +C NGW +C+H+ED GV+C S +P S + +L
Sbjct: 433 SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSL 492
Query: 180 NIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGE 239
+++ + R +G VEV +W +CD W ++ VVC G
Sbjct: 493 ALRLVNGGDRC------------QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG-- 538
Query: 240 RTYNTKVYKMFA---SRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCEN 293
+ M A +R Q P +D C+G E+++ SC +S + C +
Sbjct: 539 -------WAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN------CGH 585
Query: 294 GLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDD 353
A V C GP +RL G +GRVEVL G WGTVCDD
Sbjct: 586 SEDAGVIC--------SGPE--------SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD 629
Query: 354 KWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQ 412
WD A+VVCR+LG G A A +R GQG GPI L++++C+G+E + C N S
Sbjct: 630 SWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSH 689
Query: 413 GCNHEEDAGVRC------NTP-------------AMGLQKK--LRLNGGRNPYEGRVEVL 451
C H EDAGV C +TP +G + LRL G + +GRVEVL
Sbjct: 690 NCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVL 749
Query: 452 VERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKC 511
+ WG VC +W +A VVCRQLG G+A++A + G S +V+ V+C
Sbjct: 750 YRGS----WGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRC 802
Query: 512 SGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
SG E L C H+G G AGV CS
Sbjct: 803 SGHESYLWSCPHNG--WLSHNCGHHEDAGVICS 833
Score = 145 bits (366), Expect = 1e-34
Identities = 95/242 (39%), Positives = 120/242 (49%), Gaps = 32/242 (13%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
+RL G +GRVE+L G WGTVCDD WD A+VVCR+LG G A A + GQG
Sbjct: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
Query: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN------------------- 425
GPI L++++C+G+E + C N S C H EDAGV C+
Sbjct: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221
Query: 426 -TPAMGLQKK--LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGL 482
P G + LRL G + GRVEVL + WG VC W +A VVCRQLG
Sbjct: 222 PVPTEGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCDDYWDTNDANVVCRQLGC 277
Query: 483 GFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVA 542
G+A +A + G S +V+ V+CSG E L C H+G G AGV
Sbjct: 278 GWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLTHNCGHSEDAGVI 332
Query: 543 CS 544
CS
Sbjct: 333 CS 334
Score = 107 bits (266), Expect = 5e-23
Identities = 46/94 (48%), Positives = 62/94 (65%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVE+Y+ G WGTVCDD ++I A VVCR+LG A S ++ +G G GPI LD++ C+
Sbjct: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1956
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163
G E+TL C + GW +C H ED GV+CS +
Sbjct: 1957 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1990
Score = 103 bits (256), Expect = 8e-22
Identities = 47/94 (50%), Positives = 63/94 (67%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C+
Sbjct: 1651 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 1710
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163
GNE+ L +C GW +C H ED GV+CS +I
Sbjct: 1711 GNESYLWSCPHKGWLTHNCGHHEDAGVICSATQI 1744
Score = 98.2 bits (243), Expect = 3e-20
Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Query: 325 LVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQG 384
LV L + GRVE+ G WGTVCDD W + A VVCR+LG G A A+ + G G
Sbjct: 1885 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG 1944
Query: 385 IGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN 425
GPI L++++C+G E ++ C+ S CNH EDAGV C+
Sbjct: 1945 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
Score = 63.5 bits (153), Expect = 7e-10
Identities = 38/99 (38%), Positives = 52/99 (52%), Gaps = 7/99 (7%)
Query: 427 PAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFAS 486
P+ + + LN GRVE+ +G WG VC +W I EA VVCRQLG G A
Sbjct: 1878 PSDATLRLVNLNSSYGLCAGRVEIY---HGG-TWGTVCDDSWTIQEAEVVCRQLGCGRAV 1933
Query: 487 NAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525
+A ++ G S + + V+CSGTE +L CR+ G
Sbjct: 1934 SALGNAYFGSG---SGPITLDDVECSGTESTLWQCRNRG 1969
Score = 39.7 bits (91), Expect = 0.011
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 9/76 (11%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G VE+ G TW +CD WT + + VVC G R + F S P ++
Sbjct: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC--GRAVSALGNAYFGSGS----GPITL 1950
Query: 264 D---CTGTEAHISSCK 276
D C+GTE+ + C+
Sbjct: 1951 DDVECSGTESTLWQCR 1966
>gi|148539844 deleted in malignant brain tumors 1 isoform c
precursor [Homo sapiens]
Length = 2403
Score = 263 bits (672), Expect = 5e-70
Identities = 186/553 (33%), Positives = 259/553 (46%), Gaps = 65/553 (11%)
Query: 6 CSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKR 65
C H + + P S + +SWP P P + + + LRL
Sbjct: 191 CGHGEDAGVICSAAQPQSTLRPESWP---VRISPPVP------TEGSESSLALRLVNGGD 241
Query: 66 KHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDN 125
+ GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD+
Sbjct: 242 R-CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
Query: 126 LHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVED 185
+ C+G+E+ L +C NGW +C H+ED GV+CS + ++ +
Sbjct: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360
Query: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGE 239
+ +R + R +G VEV +W +CD W ++ VVC G PG
Sbjct: 361 LALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGN 415
Query: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCK----LGPQVSLDPMKNVTCE 292
+R Q P +D C+G E+++ SC L V C
Sbjct: 416 ------------ARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
Query: 293 NGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCD 352
+ LP + +P + +RL G +GRVEVL G WGTVCD
Sbjct: 464 DTLPTIT--LPASTVGSE-----------SSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 510
Query: 353 DKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ES 411
D WD A+VVCR+LG G A A +R GQG GPI L++++C+GNE + C N S
Sbjct: 511 DSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLS 570
Query: 412 QGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIV 471
C H EDAGV C+ P L LRL G + +GRVEVL + WG VC +W
Sbjct: 571 HNCGHSEDAGVICSGPESSL--ALRLVNGGDRCQGRVEVLYRGS----WGTVCDDSWDTN 624
Query: 472 EAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACP 531
+A VVCRQLG G+A++A + G S +V+ V+CSG E L C ++G
Sbjct: 625 DANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPNNG--WLSH 679
Query: 532 QGGVQYGAGVACS 544
G AGV CS
Sbjct: 680 NCGHHEDAGVICS 692
Score = 257 bits (656), Expect = 3e-68
Identities = 179/504 (35%), Positives = 246/504 (48%), Gaps = 81/504 (16%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 373 QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 432
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188
+G E+ L +C NGW +C+H+ED GV+CSD +P S + +L +++ +
Sbjct: 433 SGYESYLWSCPHNGWLSHNCQHSEDAGVICSD-TLPTITLPASTVGSESSLALRLVNGGD 491
Query: 189 RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYK 248
R +G VEV +W +CD W ++ VVC G +
Sbjct: 492 RC------------QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG---------WA 530
Query: 249 MFA---SRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCV 302
M A +R Q P +D C+G E+++ SC +S + C + A V C
Sbjct: 531 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN------CGHSEDAGVIC- 583
Query: 303 PGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASV 362
GP +RL G +GRVEVL G WGTVCDD WD A+V
Sbjct: 584 -------SGPE--------SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANV 628
Query: 363 VCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAG 421
VCR+LG G A A +R GQG GPI L++++C+G+E + C N S C H EDAG
Sbjct: 629 VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAG 688
Query: 422 VRC------NTP-------------AMGLQKK--LRLNGGRNPYEGRVEVLVERNGSLVW 460
V C +TP +G + LRL G + +GRVEVL + W
Sbjct: 689 VICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGS----W 744
Query: 461 GMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAH 520
G VC +W +A VVCRQLG G+A++A + G S +V+ V+CSG E L
Sbjct: 745 GTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWS 801
Query: 521 CRHDGEDVACPQGGVQYGAGVACS 544
C H+G G AGV CS
Sbjct: 802 CPHNG--WLSHNCGHHEDAGVICS 823
Score = 256 bits (655), Expect = 4e-68
Identities = 183/514 (35%), Positives = 252/514 (49%), Gaps = 70/514 (13%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 602 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 661
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSL--INQIENLNIQVEDI 186
+G+E+ L +C +NGW +C H ED GV+CS + ++L I + +
Sbjct: 662 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL 721
Query: 187 RIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGER 240
+R + + R +G VEV +W +CD W ++ VVC G PG
Sbjct: 722 TLRLVNGSDR-----CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNA 776
Query: 241 TYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPA 297
+ Q P +D C+G E+++ SC +S + C + A
Sbjct: 777 RFG------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHHEDA 818
Query: 298 VVSCVPGQ---VFSPDG-PSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVCD 352
V C Q SPD P+ PE L +RL G +GRVEVL G WGTVCD
Sbjct: 819 GVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 878
Query: 353 DKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ES 411
D WD A+VVCR+LG G A A +R GQG GPI L++++C+G E + C N S
Sbjct: 879 DSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLS 938
Query: 412 QGCNHEEDAGVRC------NTPA-------------MGLQKK--LRLNGGRNPYEGRVEV 450
C H EDAGV C +TP+ +G + LRL G + +GRVEV
Sbjct: 939 HNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEV 998
Query: 451 LVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVK 510
L + + WG VC +W +A VVCRQLG G+A +A + G S +V+ V+
Sbjct: 999 LYQGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVR 1051
Query: 511 CSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
CSG E L C H+G G AGV CS
Sbjct: 1052 CSGHESYLWSCPHNG--WLSHNCGHSEDAGVICS 1083
Score = 255 bits (651), Expect = 1e-67
Identities = 183/513 (35%), Positives = 246/513 (47%), Gaps = 61/513 (11%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVE+ Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 112 QGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRC 171
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIEN---LNIQVED 185
+G+E+ L +C NGW +C H ED GV+CS + S +I
Sbjct: 172 SGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESS 231
Query: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGE 239
+ +R + R R G VEV +W +CD +W ++ VVC G PG
Sbjct: 232 LALRLVNGGDRCR-----GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
Query: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296
+ Q P +D C+G E+++ SC ++ + C +
Sbjct: 287 AQFG------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHN------CGHSED 328
Query: 297 AVVSCVPGQ---VFSPDG-PSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVC 351
A V C Q SPD P+ PE L +RL G +GRVEVL G WGTVC
Sbjct: 329 AGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388
Query: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-E 410
DD WD A+VVCR+LG G A A +R GQG GPI L++++C+G E + C N
Sbjct: 389 DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448
Query: 411 SQGCNHEEDAGVRCN--TPAMGLQKK---------LRLNGGRNPYEGRVEVLVERNGSLV 459
S C H EDAGV C+ P + L LRL G + +GRVEVL +
Sbjct: 449 SHNCQHSEDAGVICSDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGS---- 504
Query: 460 WGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLA 519
WG VC +W +A VVCRQLG G+A A + G S +V+ V+CSG E L
Sbjct: 505 WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG---SGPIVLDDVRCSGNESYLW 561
Query: 520 HCRHDGEDVACPQGGVQYGAGVACSETAPDLVL 552
C H+G G AGV CS L L
Sbjct: 562 SCPHNG--WLSHNCGHSEDAGVICSGPESSLAL 592
Score = 255 bits (651), Expect = 1e-67
Identities = 179/510 (35%), Positives = 245/510 (48%), Gaps = 66/510 (12%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 993 QGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 1052
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188
+G+E+ L +C NGW +C H+ED GV+CS + ++ + + +
Sbjct: 1053 SGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLAL 1112
Query: 189 RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGERTY 242
R + R +G VEV +W +CD +W ++ VVC G PG
Sbjct: 1113 RLVNGGDR-----CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN--- 1164
Query: 243 NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299
+R Q P +D C+G E+++ SC +S + C + A V
Sbjct: 1165 ---------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHHEDAGV 1209
Query: 300 SCVPGQ---VFSPD-GPSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354
C Q SPD P+ E L +RL G +GRVEVL G WGTVCDD
Sbjct: 1210 ICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDY 1269
Query: 355 WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQG 413
WD A+VVCR+LG G A A +R GQG GPI L++++C+G+E + C N S
Sbjct: 1270 WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 1329
Query: 414 CNHEEDAGVRC-------------------NTPAMGLQKKLRLNGGRNPYEGRVEVLVER 454
C H EDAGV C +T LRL G + +GRVEVL
Sbjct: 1330 CGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRG 1389
Query: 455 NGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGT 514
+ WG VC W +A VVCRQLG G+A++A + G S +V+ V+CSG
Sbjct: 1390 S----WGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGH 1442
Query: 515 ELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
E L C H+G G AGV CS
Sbjct: 1443 ESYLWSCPHNG--WLSHNCGHHEDAGVICS 1470
Score = 254 bits (649), Expect = 2e-67
Identities = 178/514 (34%), Positives = 242/514 (47%), Gaps = 68/514 (13%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 1251 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1310
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188
+G+E+ L +C NGW +C H ED GV+CS + ++ + + +
Sbjct: 1311 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL 1370
Query: 189 RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGERTY 242
R + R +G VEV +W +CD +W ++ VVC G PG +
Sbjct: 1371 RLVNGGDR-----CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF 1425
Query: 243 NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299
Q P +D C+G E+++ SC +S + C + A V
Sbjct: 1426 G------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHHEDAGV 1467
Query: 300 SCVPGQVFSPDGP-----SRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354
C Q P SR A +RL G GRVEVL G WGTVCDD
Sbjct: 1468 ICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDY 1527
Query: 355 WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAE-SQG 413
WD A+VVCR+LG G A A ++ GQG GPI L++++C+G+E + C N S
Sbjct: 1528 WDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 1587
Query: 414 CNHEEDAGVRC-----------------NTPAMGLQKK----LRLNGGRNPYEGRVEVLV 452
C H EDAGV C N PA+ + + LRL G + GRVEVL
Sbjct: 1588 CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLY 1647
Query: 453 ERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCS 512
+ WG VC +W +A VVCRQLG G+A +A + G S +V+ V+CS
Sbjct: 1648 RGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCS 1700
Query: 513 GTELSLAHCRHDGEDVACPQGGVQYGAGVACSET 546
G E L C H G G AGV CS T
Sbjct: 1701 GNESYLWSCPHKG--WLTHNCGHHEDAGVICSAT 1732
Score = 253 bits (646), Expect = 5e-67
Identities = 181/519 (34%), Positives = 245/519 (47%), Gaps = 82/519 (15%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 862 QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 921
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVC---------SDKRIPGFKFDNSLINQIENL 179
+G E+ L +C NGW +C+H+ED GV+C S +P S + +L
Sbjct: 922 SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSL 981
Query: 180 NIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG---- 235
+++ + R +G VEV +W +CD W ++ VVC G
Sbjct: 982 ALRLVNGGDRC------------QGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWA 1029
Query: 236 --FPGERTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVT 290
PG +R Q P +D C+G E+++ SC +S +
Sbjct: 1030 MSAPGN------------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------ 1071
Query: 291 CENGLPAVVSCVPGQ---VFSPD-GPSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNG 345
C + A V C Q SPD P+ E L +RL G +GRVEVL G
Sbjct: 1072 CGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRG 1131
Query: 346 EWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDC 405
WGTVCDD WD A+VVCR+LG G A A +R GQG GPI L++++C+G+E + C
Sbjct: 1132 SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSC 1191
Query: 406 KFNA-ESQGCNHEEDAGVRC-------------------NTPAMGLQKKLRLNGGRNPYE 445
N S C H EDAGV C +T LRL G + +
Sbjct: 1192 PHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQ 1251
Query: 446 GRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVV 505
GRVEVL + WG VC W +A VVCRQLG G+A++A + G S +V
Sbjct: 1252 GRVEVLYRGS----WGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIV 1304
Query: 506 MSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
+ V+CSG E L C H+G G AGV CS
Sbjct: 1305 LDDVRCSGHESYLWSCPHNG--WLSHNCGHHEDAGVICS 1341
Score = 179 bits (454), Expect = 9e-45
Identities = 132/393 (33%), Positives = 179/393 (45%), Gaps = 66/393 (16%)
Query: 203 EGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGERTYNTKVYKMFASRRKQ 256
+G VE+ +W +CD W ++ VVC G PG + Q
Sbjct: 112 QGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFG------------Q 159
Query: 257 RYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPS 313
P ++D C+G E+++ SC +S + C +G A V C Q S P
Sbjct: 160 GSGPIALDDVRCSGHESYLWSCPHNGWLSHN------CGHGEDAGVICSAAQPQSTLRPE 213
Query: 314 RFRKAYKPEQPL--------VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCR 365
+ P P +RL G GRVEVL G WGTVCDD WD A+VVCR
Sbjct: 214 SWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCR 273
Query: 366 ELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRC 424
+LG G A A ++ GQG GPI L++++C+G+E + C N + C H EDAGV C
Sbjct: 274 QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVIC 333
Query: 425 NTP-----------------AMGLQKK--LRLNGGRNPYEGRVEVLVERNGSLVWGMVCG 465
+ P G + LRL G + +GRVEVL + WG VC
Sbjct: 334 SAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGS----WGTVCD 389
Query: 466 QNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525
+W +A VVCRQLG G+A++A + G S +V+ V+CSG E L C H+G
Sbjct: 390 DSWDTSDANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGYESYLWSCPHNG 446
Query: 526 -EDVACPQGGVQYGAGVACSETAPDLVLNAEMV 557
C AGV CS+T P + L A V
Sbjct: 447 WLSHNCQH---SEDAGVICSDTLPTITLPASTV 476
Score = 145 bits (366), Expect = 1e-34
Identities = 95/242 (39%), Positives = 120/242 (49%), Gaps = 32/242 (13%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
+RL G +GRVE+L G WGTVCDD WD A+VVCR+LG G A A + GQG
Sbjct: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
Query: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN------------------- 425
GPI L++++C+G+E + C N S C H EDAGV C+
Sbjct: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221
Query: 426 -TPAMGLQKK--LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGL 482
P G + LRL G + GRVEVL + WG VC W +A VVCRQLG
Sbjct: 222 PVPTEGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCDDYWDTNDANVVCRQLGC 277
Query: 483 GFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVA 542
G+A +A + G S +V+ V+CSG E L C H+G G AGV
Sbjct: 278 GWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLTHNCGHSEDAGVI 332
Query: 543 CS 544
CS
Sbjct: 333 CS 334
Score = 107 bits (266), Expect = 5e-23
Identities = 46/94 (48%), Positives = 62/94 (65%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVE+Y+ G WGTVCDD ++I A VVCR+LG A S ++ +G G GPI LD++ C+
Sbjct: 1887 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1946
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163
G E+TL C + GW +C H ED GV+CS +
Sbjct: 1947 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1980
Score = 103 bits (256), Expect = 8e-22
Identities = 47/94 (50%), Positives = 63/94 (67%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C+
Sbjct: 1641 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 1700
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163
GNE+ L +C GW +C H ED GV+CS +I
Sbjct: 1701 GNESYLWSCPHKGWLTHNCGHHEDAGVICSATQI 1734
Score = 98.2 bits (243), Expect = 3e-20
Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Query: 325 LVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQG 384
LV L + GRVE+ G WGTVCDD W + A VVCR+LG G A A+ + G G
Sbjct: 1875 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG 1934
Query: 385 IGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN 425
GPI L++++C+G E ++ C+ S CNH EDAGV C+
Sbjct: 1935 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1976
Score = 63.5 bits (153), Expect = 7e-10
Identities = 38/99 (38%), Positives = 52/99 (52%), Gaps = 7/99 (7%)
Query: 427 PAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFAS 486
P+ + + LN GRVE+ +G WG VC +W I EA VVCRQLG G A
Sbjct: 1868 PSDATLRLVNLNSSYGLCAGRVEIY---HGG-TWGTVCDDSWTIQEAEVVCRQLGCGRAV 1923
Query: 487 NAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525
+A ++ G S + + V+CSGTE +L CR+ G
Sbjct: 1924 SALGNAYFGSG---SGPITLDDVECSGTESTLWQCRNRG 1959
Score = 39.7 bits (91), Expect = 0.011
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 9/76 (11%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G VE+ G TW +CD WT + + VVC G R + F S P ++
Sbjct: 1887 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC--GRAVSALGNAYFGSGS----GPITL 1940
Query: 264 D---CTGTEAHISSCK 276
D C+GTE+ + C+
Sbjct: 1941 DDVECSGTESTLWQCR 1956
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 257 bits (656), Expect = 3e-68
Identities = 190/581 (32%), Positives = 263/581 (45%), Gaps = 84/581 (14%)
Query: 6 CSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKR 65
C H + + P S + +SWP P P + + + LRL
Sbjct: 191 CGHGEDAGVICSAAQPQSTLRPESWP---VRISPPVP------TEGSESSLALRLVNGGD 241
Query: 66 KHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDN 125
+ GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD+
Sbjct: 242 R-CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
Query: 126 LHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVED 185
+ C+G+E+ L +C NGW +C H+ED GV+CS + ++ +
Sbjct: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360
Query: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGE 239
+ +R + R +G VEV +W +CD W ++ VVC G PG
Sbjct: 361 LALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGN 415
Query: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296
+ Q P +D C+G E+++ SC +S + C++
Sbjct: 416 ARFG------------QGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN------CQHSED 457
Query: 297 AVVSCVPGQVFSPDGPS-RFRKAYKPEQPL------------VRLRGGAYIGEGRVEVLK 343
A V C +S P R R P L +RL G +GRVEVL
Sbjct: 458 AGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLY 517
Query: 344 NGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSII 403
G WGTVCDD WD A+VVCR+LG G A A +R GQG GPI L++++C+GNE +
Sbjct: 518 RGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLW 577
Query: 404 DCKFNA-ESQGCNHEEDAGVRC-------------------NTPAMGLQKKLRLNGGRNP 443
C N S C H EDAGV C +T LRL G +
Sbjct: 578 SCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDR 637
Query: 444 YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503
+GRVEVL + + WG VC +W +A VVCRQLG G+A +A + G S
Sbjct: 638 CQGRVEVLYQGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGP 690
Query: 504 VVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
+V+ V+CSG E L C H+G G AGV CS
Sbjct: 691 IVLDDVRCSGHESYLWSCPHNG--WLSHNCGHSEDAGVICS 729
Score = 255 bits (652), Expect = 1e-67
Identities = 181/514 (35%), Positives = 244/514 (47%), Gaps = 68/514 (13%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + + A+VVCR+LG A ++ +G+G GPI LD++ C
Sbjct: 510 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRC 569
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188
+GNE+ L +C NGW +C H+ED GV+CS + ++ + + +
Sbjct: 570 SGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLAL 629
Query: 189 RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGERTY 242
R + R +G VEV +W +CD W ++ VVC G PG
Sbjct: 630 RLVNGGDR-----CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN--- 681
Query: 243 NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299
+R Q P +D C+G E+++ SC +S + C + A V
Sbjct: 682 ---------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHSEDAGV 726
Query: 300 SCVPGQ---VFSPD--GPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354
C Q SPD SR A +RL G GRVEVL G WGTVCDD
Sbjct: 727 ICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDY 786
Query: 355 WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQG 413
WD A+VVCR+LG G A A ++ GQG GPI L++++C+G+E + C N S
Sbjct: 787 WDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 846
Query: 414 CNHEEDAGVRC-----------------NTPAMGLQKK----LRLNGGRNPYEGRVEVLV 452
C H EDAGV C N PA+ + + LRL G + GRVEVL
Sbjct: 847 CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLY 906
Query: 453 ERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCS 512
+ WG VC +W +A VVCRQLG G+A +A + G S +V+ V+CS
Sbjct: 907 RGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCS 959
Query: 513 GTELSLAHCRHDGEDVACPQGGVQYGAGVACSET 546
G E L C H G G AGV CS T
Sbjct: 960 GNESYLWSCPHKG--WLTHNCGHHEDAGVICSAT 991
Score = 248 bits (633), Expect = 2e-65
Identities = 181/521 (34%), Positives = 246/521 (47%), Gaps = 77/521 (14%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVE+ Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 112 QGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRC 171
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNS---LINQIENLNIQVED 185
+G+E+ L +C NGW +C H ED GV+CS + S I+
Sbjct: 172 SGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESS 231
Query: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGE 239
+ +R + R R G VEV +W +CD +W ++ VVC G PG
Sbjct: 232 LALRLVNGGDRCR-----GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
Query: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296
+ Q P +D C+G E+++ SC ++ + C +
Sbjct: 287 AQFG------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHN------CGHSED 328
Query: 297 AVVSCVPGQ---VFSPD-GPSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVC 351
A V C Q SPD P+ E L +RL G +GRVEVL G WGTVC
Sbjct: 329 AGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388
Query: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-E 410
DD WD A+VVCR+LG G A A +R GQG GPI L++++C+G E + C N
Sbjct: 389 DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448
Query: 411 SQGCNHEEDAGVRC------NTPAMGLQKK---------------------LRLNGGRNP 443
S C H EDAGV C +TP+ G + + LRL G +
Sbjct: 449 SHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDR 508
Query: 444 YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503
+GRVEVL + WG VC +W +A VVCRQLG G+A A + G S
Sbjct: 509 CQGRVEVLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG---SGP 561
Query: 504 VVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
+V+ V+CSG E L C H+G G AGV CS
Sbjct: 562 IVLDDVRCSGNESYLWSCPHNG--WLSHNCGHSEDAGVICS 600
Score = 145 bits (366), Expect = 1e-34
Identities = 95/242 (39%), Positives = 120/242 (49%), Gaps = 32/242 (13%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
+RL G +GRVE+L G WGTVCDD WD A+VVCR+LG G A A + GQG
Sbjct: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
Query: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN------------------- 425
GPI L++++C+G+E + C N S C H EDAGV C+
Sbjct: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221
Query: 426 -TPAMGLQKK--LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGL 482
P G + LRL G + GRVEVL + WG VC W +A VVCRQLG
Sbjct: 222 PVPTEGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCDDYWDTNDANVVCRQLGC 277
Query: 483 GFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVA 542
G+A +A + G S +V+ V+CSG E L C H+G G AGV
Sbjct: 278 GWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLTHNCGHSEDAGVI 332
Query: 543 CS 544
CS
Sbjct: 333 CS 334
Score = 107 bits (266), Expect = 5e-23
Identities = 46/94 (48%), Positives = 62/94 (65%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVE+Y+ G WGTVCDD ++I A VVCR+LG A S ++ +G G GPI LD++ C+
Sbjct: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1205
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163
G E+TL C + GW +C H ED GV+CS +
Sbjct: 1206 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1239
Score = 103 bits (256), Expect = 8e-22
Identities = 47/94 (50%), Positives = 63/94 (67%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C+
Sbjct: 900 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 959
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163
GNE+ L +C GW +C H ED GV+CS +I
Sbjct: 960 GNESYLWSCPHKGWLTHNCGHHEDAGVICSATQI 993
Score = 98.2 bits (243), Expect = 3e-20
Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Query: 325 LVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQG 384
LV L + GRVE+ G WGTVCDD W + A VVCR+LG G A A+ + G G
Sbjct: 1134 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG 1193
Query: 385 IGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN 425
GPI L++++C+G E ++ C+ S CNH EDAGV C+
Sbjct: 1194 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
Score = 63.5 bits (153), Expect = 7e-10
Identities = 38/99 (38%), Positives = 52/99 (52%), Gaps = 7/99 (7%)
Query: 427 PAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFAS 486
P+ + + LN GRVE+ +G WG VC +W I EA VVCRQLG G A
Sbjct: 1127 PSDATLRLVNLNSSYGLCAGRVEIY---HGG-TWGTVCDDSWTIQEAEVVCRQLGCGRAV 1182
Query: 487 NAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525
+A ++ G S + + V+CSGTE +L CR+ G
Sbjct: 1183 SALGNAYFGSG---SGPITLDDVECSGTESTLWQCRNRG 1218
Score = 39.7 bits (91), Expect = 0.011
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 9/76 (11%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G VE+ G TW +CD WT + + VVC G R + F S P ++
Sbjct: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC--GRAVSALGNAYFGSGS----GPITL 1199
Query: 264 D---CTGTEAHISSCK 276
D C+GTE+ + C+
Sbjct: 1200 DDVECSGTESTLWQCR 1215
>gi|148539840 deleted in malignant brain tumors 1 isoform a
precursor [Homo sapiens]
Length = 1785
Score = 257 bits (656), Expect = 3e-68
Identities = 187/575 (32%), Positives = 260/575 (45%), Gaps = 78/575 (13%)
Query: 6 CSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKR 65
C H + + P S + +SWP P P + + + LRL
Sbjct: 191 CGHGEDAGVICSAAQPQSTLRPESWP---VRISPPVP------TEGSESSLALRLVNGGD 241
Query: 66 KHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDN 125
+ GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD+
Sbjct: 242 R-CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
Query: 126 LHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVED 185
+ C+G+E+ L +C NGW +C H+ED GV+CS + ++ +
Sbjct: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360
Query: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGE 239
+ +R + R +G VEV +W +CD W ++ VVC G PG
Sbjct: 361 LALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGN 415
Query: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296
+R Q P +D C+G E+++ SC +S + C++
Sbjct: 416 ------------ARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN------CQHSED 457
Query: 297 AVVSCVPGQVFSPDGPSRFRKAYKPEQPL-------VRLRGGAYIGEGRVEVLKNGEWGT 349
A V C +S P P + +RL G +GRVEVL G WGT
Sbjct: 458 AGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGT 517
Query: 350 VCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA 409
VCDD WD A+VVCR+LG G A A +R GQG GPI L++++C+G+E + C N
Sbjct: 518 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 577
Query: 410 -ESQGCNHEEDAGVRC-------------------NTPAMGLQKKLRLNGGRNPYEGRVE 449
S C H EDAGV C +T LRL G + +GRVE
Sbjct: 578 WLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVE 637
Query: 450 VLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGV 509
VL + WG VC W +A VVCRQLG G+A +A + G S +V+ V
Sbjct: 638 VLYRGS----WGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDV 690
Query: 510 KCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
+CSG E L C H+G G AGV CS
Sbjct: 691 RCSGHESYLWSCPHNG--WLSHNCGHHEDAGVICS 723
Score = 254 bits (649), Expect = 2e-67
Identities = 179/510 (35%), Positives = 244/510 (47%), Gaps = 66/510 (12%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 504 QGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 563
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188
+G+E+ L +C NGW +C H+ED GV+CS + ++ + + +
Sbjct: 564 SGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLAL 623
Query: 189 RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGERTY 242
R + R +G VEV +W +CD +W ++ VVC G PG
Sbjct: 624 RLVNGGDR-----CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN--- 675
Query: 243 NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299
+R Q P +D C+G E+++ SC +S + C + A V
Sbjct: 676 ---------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHHEDAGV 720
Query: 300 SCVPGQ---VFSPD-GPSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354
C Q SPD P+ E L +RL G +GRVEVL G WGTVCDD
Sbjct: 721 ICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDY 780
Query: 355 WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQG 413
WD A+VVCR+LG G A A +R GQG GPI L++++C+G+E + C N S
Sbjct: 781 WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 840
Query: 414 CNHEEDAGVRC-------------------NTPAMGLQKKLRLNGGRNPYEGRVEVLVER 454
C H EDAGV C +T LRL G + GRVEVL +
Sbjct: 841 CGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG 900
Query: 455 NGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGT 514
+ WG VC W +A VVCRQLG G+A +A + G S +V+ V+CSG
Sbjct: 901 S----WGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG---SGPIVLDDVRCSGH 953
Query: 515 ELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
E L C H+G G AGV CS
Sbjct: 954 ESYLWSCPHNG--WLSHNCGHHEDAGVICS 981
Score = 254 bits (649), Expect = 2e-67
Identities = 178/514 (34%), Positives = 242/514 (47%), Gaps = 68/514 (13%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 633 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 692
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188
+G+E+ L +C NGW +C H ED GV+CS + ++ + + +
Sbjct: 693 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL 752
Query: 189 RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGERTY 242
R + R +G VEV +W +CD +W ++ VVC G PG +
Sbjct: 753 RLVNGGDR-----CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF 807
Query: 243 NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299
Q P +D C+G E+++ SC +S + C + A V
Sbjct: 808 G------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHHEDAGV 849
Query: 300 SCVPGQVFSPDGP-----SRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354
C Q P SR A +RL G GRVEVL G WGTVCDD
Sbjct: 850 ICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDY 909
Query: 355 WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAE-SQG 413
WD A+VVCR+LG G A A ++ GQG GPI L++++C+G+E + C N S
Sbjct: 910 WDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 969
Query: 414 CNHEEDAGVRC-----------------NTPAMGLQKK----LRLNGGRNPYEGRVEVLV 452
C H EDAGV C N PA+ + + LRL G + GRVEVL
Sbjct: 970 CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLY 1029
Query: 453 ERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCS 512
+ WG VC +W +A VVCRQLG G+A +A + G S +V+ V+CS
Sbjct: 1030 RGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCS 1082
Query: 513 GTELSLAHCRHDGEDVACPQGGVQYGAGVACSET 546
G E L C H G G AGV CS T
Sbjct: 1083 GNESYLWSCPHKG--WLTHNCGHHEDAGVICSAT 1114
Score = 253 bits (646), Expect = 5e-67
Identities = 181/519 (34%), Positives = 245/519 (47%), Gaps = 82/519 (15%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 373 QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 432
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVC---------SDKRIPGFKFDNSLINQIENL 179
+G E+ L +C NGW +C+H+ED GV+C S +P S + +L
Sbjct: 433 SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSL 492
Query: 180 NIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG---- 235
+++ + R +G VEV +W +CD W ++ VVC G
Sbjct: 493 ALRLVNGGDRC------------QGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWA 540
Query: 236 --FPGERTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVT 290
PG +R Q P +D C+G E+++ SC +S +
Sbjct: 541 MSAPGN------------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------ 582
Query: 291 CENGLPAVVSCVPGQ---VFSPD-GPSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNG 345
C + A V C Q SPD P+ E L +RL G +GRVEVL G
Sbjct: 583 CGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRG 642
Query: 346 EWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDC 405
WGTVCDD WD A+VVCR+LG G A A +R GQG GPI L++++C+G+E + C
Sbjct: 643 SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSC 702
Query: 406 KFNA-ESQGCNHEEDAGVRC-------------------NTPAMGLQKKLRLNGGRNPYE 445
N S C H EDAGV C +T LRL G + +
Sbjct: 703 PHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQ 762
Query: 446 GRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVV 505
GRVEVL + WG VC W +A VVCRQLG G+A++A + G S +V
Sbjct: 763 GRVEVLYRGS----WGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIV 815
Query: 506 MSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
+ V+CSG E L C H+G G AGV CS
Sbjct: 816 LDDVRCSGHESYLWSCPHNG--WLSHNCGHHEDAGVICS 852
Score = 252 bits (644), Expect = 8e-67
Identities = 182/515 (35%), Positives = 249/515 (48%), Gaps = 71/515 (13%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVE+ Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 112 QGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRC 171
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIEN---LNIQVED 185
+G+E+ L +C NGW +C H ED GV+CS + S +I
Sbjct: 172 SGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESS 231
Query: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGE 239
+ +R + R R G VEV +W +CD +W ++ VVC G PG
Sbjct: 232 LALRLVNGGDRCR-----GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
Query: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296
+ Q P +D C+G E+++ SC ++ + C +
Sbjct: 287 AQFG------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHN------CGHSED 328
Query: 297 AVVSCVPGQ---VFSPDG-PSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVC 351
A V C Q SPD P+ PE L +RL G +GRVEVL G WGTVC
Sbjct: 329 AGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388
Query: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-E 410
DD WD A+VVCR+LG G A A +R GQG GPI L++++C+G E + C N
Sbjct: 389 DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448
Query: 411 SQGCNHEEDAGVRC------NTPA-------------MGLQKK--LRLNGGRNPYEGRVE 449
S C H EDAGV C +TP+ +G + LRL G + +GRVE
Sbjct: 449 SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508
Query: 450 VLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGV 509
VL + + WG VC +W +A VVCRQLG G+A +A + G S +V+ V
Sbjct: 509 VLYQGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDV 561
Query: 510 KCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
+CSG E L C H+G G AGV CS
Sbjct: 562 RCSGHESYLWSCPHNG--WLSHNCGHSEDAGVICS 594
Score = 145 bits (366), Expect = 1e-34
Identities = 95/242 (39%), Positives = 120/242 (49%), Gaps = 32/242 (13%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
+RL G +GRVE+L G WGTVCDD WD A+VVCR+LG G A A + GQG
Sbjct: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
Query: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN------------------- 425
GPI L++++C+G+E + C N S C H EDAGV C+
Sbjct: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221
Query: 426 -TPAMGLQKK--LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGL 482
P G + LRL G + GRVEVL + WG VC W +A VVCRQLG
Sbjct: 222 PVPTEGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCDDYWDTNDANVVCRQLGC 277
Query: 483 GFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVA 542
G+A +A + G S +V+ V+CSG E L C H+G G AGV
Sbjct: 278 GWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLTHNCGHSEDAGVI 332
Query: 543 CS 544
CS
Sbjct: 333 CS 334
Score = 107 bits (266), Expect = 5e-23
Identities = 46/94 (48%), Positives = 62/94 (65%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVE+Y+ G WGTVCDD ++I A VVCR+LG A S ++ +G G GPI LD++ C+
Sbjct: 1269 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1328
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163
G E+TL C + GW +C H ED GV+CS +
Sbjct: 1329 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1362
Score = 103 bits (256), Expect = 8e-22
Identities = 47/94 (50%), Positives = 63/94 (67%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C+
Sbjct: 1023 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 1082
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163
GNE+ L +C GW +C H ED GV+CS +I
Sbjct: 1083 GNESYLWSCPHKGWLTHNCGHHEDAGVICSATQI 1116
Score = 98.2 bits (243), Expect = 3e-20
Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Query: 325 LVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQG 384
LV L + GRVE+ G WGTVCDD W + A VVCR+LG G A A+ + G G
Sbjct: 1257 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG 1316
Query: 385 IGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN 425
GPI L++++C+G E ++ C+ S CNH EDAGV C+
Sbjct: 1317 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1358
Score = 63.5 bits (153), Expect = 7e-10
Identities = 38/99 (38%), Positives = 52/99 (52%), Gaps = 7/99 (7%)
Query: 427 PAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFAS 486
P+ + + LN GRVE+ +G WG VC +W I EA VVCRQLG G A
Sbjct: 1250 PSDATLRLVNLNSSYGLCAGRVEIY---HGG-TWGTVCDDSWTIQEAEVVCRQLGCGRAV 1305
Query: 487 NAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525
+A ++ G S + + V+CSGTE +L CR+ G
Sbjct: 1306 SALGNAYFGSG---SGPITLDDVECSGTESTLWQCRNRG 1341
Score = 39.7 bits (91), Expect = 0.011
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 9/76 (11%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G VE+ G TW +CD WT + + VVC G R + F S P ++
Sbjct: 1269 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC--GRAVSALGNAYFGSGS----GPITL 1322
Query: 264 D---CTGTEAHISSCK 276
D C+GTE+ + C+
Sbjct: 1323 DDVECSGTESTLWQCR 1338
>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
Length = 1788
Score = 256 bits (654), Expect = 6e-68
Identities = 190/578 (32%), Positives = 266/578 (46%), Gaps = 81/578 (14%)
Query: 6 CSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKR 65
C H + + P S + +SWP P P + + + LRL
Sbjct: 191 CGHGEDAGVICSAAQPQSTLRPESWP---VRISPPVP------TEGSESSLALRLVNGGD 241
Query: 66 KHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDN 125
+ GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD+
Sbjct: 242 R-CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
Query: 126 LHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVED 185
+ C+G+E+ L +C NGW +C H+ED GV+CS + ++ +
Sbjct: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360
Query: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGE 239
+ +R + R +G VEV +W +CD W ++ VVC G PG
Sbjct: 361 LALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGN 415
Query: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296
+R Q P +D C+G E+++ SC +S + C++
Sbjct: 416 ------------ARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN------CQHSED 457
Query: 297 AVVSCVPGQVFSPDGPSRFRKAYKPEQPL-------VRLRGGAYIGEGRVEVLKNGEWGT 349
A V C +S P P + +RL G +GRVEVL G WGT
Sbjct: 458 AGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 517
Query: 350 VCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA 409
VCDD WD A+VVCR+LG G A A +R GQG GPI L++++C+GNE + C N
Sbjct: 518 VCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNG 577
Query: 410 -ESQGCNHEEDAGVRCN------TP--------AMGLQK--------KLRLNGGRNPYEG 446
S C H EDAGV C+ TP + LQ LRL G + +G
Sbjct: 578 WLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQG 637
Query: 447 RVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVM 506
RVEVL + WG VC +W +A VVCRQLG G+A++A + G S +V+
Sbjct: 638 RVEVLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIVL 690
Query: 507 SGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
V+CSG E L C ++G G AGV CS
Sbjct: 691 DDVRCSGHESYLWSCPNNG--WLSHNCGHHEDAGVICS 726
Score = 255 bits (652), Expect = 1e-67
Identities = 181/514 (35%), Positives = 245/514 (47%), Gaps = 68/514 (13%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 636 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 695
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188
+G+E+ L +C +NGW +C H ED GV+CS + ++ + + +
Sbjct: 696 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLAL 755
Query: 189 RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGERTY 242
R + R +G VEV +W +CD W ++ VVC G PG
Sbjct: 756 RLVNGGDR-----CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN--- 807
Query: 243 NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299
+R Q P +D C+G E+++ SC +S + C + A V
Sbjct: 808 ---------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHSEDAGV 852
Query: 300 SCVPGQ---VFSPD--GPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354
C Q SPD SR A +RL G GRVEVL G WGTVCDD
Sbjct: 853 ICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDY 912
Query: 355 WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQG 413
WD A+VVCR+LG G A A ++ GQG GPI L++++C+G+E + C N S
Sbjct: 913 WDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 972
Query: 414 CNHEEDAGVRC-----------------NTPAMGLQKK----LRLNGGRNPYEGRVEVLV 452
C H EDAGV C N PA+ + + LRL G + GRVEVL
Sbjct: 973 CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLY 1032
Query: 453 ERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCS 512
+ WG VC +W +A VVCRQLG G+A +A + G S +V+ V+CS
Sbjct: 1033 RGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCS 1085
Query: 513 GTELSLAHCRHDGEDVACPQGGVQYGAGVACSET 546
G E L C H G G AGV CS T
Sbjct: 1086 GNESYLWSCPHKG--WLTHNCGHHEDAGVICSAT 1117
Score = 254 bits (649), Expect = 2e-67
Identities = 180/519 (34%), Positives = 248/519 (47%), Gaps = 79/519 (15%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 373 QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 432
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVC---------SDKRIPGFKFDNSLINQIENL 179
+G E+ L +C NGW +C+H+ED GV+C S +P S + +L
Sbjct: 433 SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSL 492
Query: 180 NIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGE 239
+++ + R +G VEV +W +CD W ++ VVC G
Sbjct: 493 ALRLVNGGDRC------------QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG-- 538
Query: 240 RTYNTKVYKMFA---SRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCEN 293
+ M A +R Q P +D C+G E+++ SC +S + C +
Sbjct: 539 -------WAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN------CGH 585
Query: 294 GLPAVVSC-----VPGQVFSPDGPS--RFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNG 345
A V C +P + PS + PE L +RL G +GRVEVL G
Sbjct: 586 SEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRG 645
Query: 346 EWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDC 405
WGTVCDD WD A+VVCR+LG G A A +R GQG GPI L++++C+G+E + C
Sbjct: 646 SWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSC 705
Query: 406 KFNA-ESQGCNHEEDAGVRC-------------------NTPAMGLQKKLRLNGGRNPYE 445
N S C H EDAGV C +T LRL G + +
Sbjct: 706 PNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQ 765
Query: 446 GRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVV 505
GRVEVL + + WG VC +W +A VVCRQLG G+A +A + G S +V
Sbjct: 766 GRVEVLYQGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIV 818
Query: 506 MSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
+ V+CSG E L C H+G G AGV CS
Sbjct: 819 LDDVRCSGHESYLWSCPHNG--WLSHNCGHSEDAGVICS 855
Score = 248 bits (632), Expect = 2e-65
Identities = 181/515 (35%), Positives = 246/515 (47%), Gaps = 71/515 (13%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVE+ Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C
Sbjct: 112 QGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRC 171
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIEN---LNIQVED 185
+G+E+ L +C NGW +C H ED GV+CS + S +I
Sbjct: 172 SGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESS 231
Query: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGE 239
+ +R + R R G VEV +W +CD +W ++ VVC G PG
Sbjct: 232 LALRLVNGGDRCR-----GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
Query: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296
+ Q P +D C+G E+++ SC ++ + C +
Sbjct: 287 AQFG------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHN------CGHSED 328
Query: 297 AVVSCVPGQ---VFSPDG-PSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVC 351
A V C Q SPD P+ E L +RL G +GRVEVL G WGTVC
Sbjct: 329 AGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388
Query: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-E 410
DD WD A+VVCR+LG G A A +R GQG GPI L++++C+G E + C N
Sbjct: 389 DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448
Query: 411 SQGCNHEEDAGVRC------NTPA-------------MGLQKK--LRLNGGRNPYEGRVE 449
S C H EDAGV C +TP+ +G + LRL G + +GRVE
Sbjct: 449 SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508
Query: 450 VLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGV 509
VL + WG VC +W +A VVCRQLG G+A A + G S +V+ V
Sbjct: 509 VLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG---SGPIVLDDV 561
Query: 510 KCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
+CSG E L C H+G G AGV CS
Sbjct: 562 RCSGNESYLWSCPHNG--WLSHNCGHSEDAGVICS 594
Score = 145 bits (366), Expect = 1e-34
Identities = 95/242 (39%), Positives = 120/242 (49%), Gaps = 32/242 (13%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
+RL G +GRVE+L G WGTVCDD WD A+VVCR+LG G A A + GQG
Sbjct: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
Query: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN------------------- 425
GPI L++++C+G+E + C N S C H EDAGV C+
Sbjct: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221
Query: 426 -TPAMGLQKK--LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGL 482
P G + LRL G + GRVEVL + WG VC W +A VVCRQLG
Sbjct: 222 PVPTEGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCDDYWDTNDANVVCRQLGC 277
Query: 483 GFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVA 542
G+A +A + G S +V+ V+CSG E L C H+G G AGV
Sbjct: 278 GWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLTHNCGHSEDAGVI 332
Query: 543 CS 544
CS
Sbjct: 333 CS 334
Score = 107 bits (266), Expect = 5e-23
Identities = 46/94 (48%), Positives = 62/94 (65%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVE+Y+ G WGTVCDD ++I A VVCR+LG A S ++ +G G GPI LD++ C+
Sbjct: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1331
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163
G E+TL C + GW +C H ED GV+CS +
Sbjct: 1332 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1365
Score = 103 bits (256), Expect = 8e-22
Identities = 47/94 (50%), Positives = 63/94 (67%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C+
Sbjct: 1026 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 1085
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163
GNE+ L +C GW +C H ED GV+CS +I
Sbjct: 1086 GNESYLWSCPHKGWLTHNCGHHEDAGVICSATQI 1119
Score = 98.2 bits (243), Expect = 3e-20
Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
Query: 325 LVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQG 384
LV L + GRVE+ G WGTVCDD W + A VVCR+LG G A A+ + G G
Sbjct: 1260 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG 1319
Query: 385 IGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN 425
GPI L++++C+G E ++ C+ S CNH EDAGV C+
Sbjct: 1320 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361
Score = 63.5 bits (153), Expect = 7e-10
Identities = 38/99 (38%), Positives = 52/99 (52%), Gaps = 7/99 (7%)
Query: 427 PAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFAS 486
P+ + + LN GRVE+ +G WG VC +W I EA VVCRQLG G A
Sbjct: 1253 PSDATLRLVNLNSSYGLCAGRVEIY---HGG-TWGTVCDDSWTIQEAEVVCRQLGCGRAV 1308
Query: 487 NAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525
+A ++ G S + + V+CSGTE +L CR+ G
Sbjct: 1309 SALGNAYFGSG---SGPITLDDVECSGTESTLWQCRNRG 1344
Score = 39.7 bits (91), Expect = 0.011
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 9/76 (11%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G VE+ G TW +CD WT + + VVC G R + F S P ++
Sbjct: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC--GRAVSALGNAYFGSGS----GPITL 1325
Query: 264 D---CTGTEAHISSCK 276
D C+GTE+ + C+
Sbjct: 1326 DDVECSGTESTLWQCR 1341
>gi|18152779 scavenger receptor cysteine rich domain containing,
group B (4 domains) [Homo sapiens]
Length = 575
Score = 225 bits (574), Expect = 1e-58
Identities = 168/515 (32%), Positives = 227/515 (44%), Gaps = 65/515 (12%)
Query: 57 QLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGK 116
+LRL G + GR+EV + G WG+VCDDD+ + A+VVCR+LG A ++G+
Sbjct: 57 ELRLVGGPSR-CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQ 115
Query: 117 GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSD---KRIPGFKFDNSLI 173
G GPI LDN+ C G EA L+ C S GWGV +C H EDV V+C + + P K S
Sbjct: 116 GRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRA 175
Query: 174 NQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGM 233
N + E +R + + +G VE+ W +CD W ++ VVC
Sbjct: 176 PPTTLPNGKSEG-SVRLVGGAN-----LCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQ 229
Query: 234 FGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCK-LGPQV---SLDPMKNV 289
G T + + + ++ C G E +++C+ LG V
Sbjct: 230 LGCGAAMAATTNAFFGYGTGH---ILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGA 286
Query: 290 TCENGLPAVVSCVPGQVFSPD------------GPSRFRK---------AYKPEQPLVRL 328
C P ++ +P D GP R+ A + +RL
Sbjct: 287 LCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRL 346
Query: 329 RGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPI 388
GG GRVEVL G WGTVCDD WD A V CRE G G A A G G GP+
Sbjct: 347 VGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPV 406
Query: 389 HLNEIQCTGNEKSIIDCKFNAESQ-GCNHEEDAGVRCNTP-AMGLQKK------------ 434
L+ + C G E + DC Q C H EDAG C P +GLQ +
Sbjct: 407 LLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTP 466
Query: 435 ------LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNA 488
LRL G + EGRVE+ + + WG VC W + A V+CRQLG G A A
Sbjct: 467 RPRDGHLRLVNGAHRCEGRVELYLGQR----WGTVCDDAWDLRAAGVLCRQLGCGQALAA 522
Query: 489 FQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRH 523
E + G +++ VKC G E +L C H
Sbjct: 523 PGEAHFGPG---RGPILLDNVKCRGEESALLLCSH 554
Score = 191 bits (484), Expect = 3e-48
Identities = 134/387 (34%), Positives = 181/387 (46%), Gaps = 44/387 (11%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVE+ + G WGTVCDDD+ + A VVCR+LG A + T ++ +G G G I LDN+HC
Sbjct: 199 QGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHC 258
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGF--------KFDNSLINQIENLN 180
G E LAAC S GWGV +C H ED G +C+ P + D +
Sbjct: 259 EGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATG 318
Query: 181 IQVEDIRIRAILSTYR----KRTPVME---------GYVEVKEGKTWKQICDKHWTAKNS 227
+ + R A+L+T K++ + G VEV W +CD W ++
Sbjct: 319 VGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADA 378
Query: 228 RVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSC-KLGPQVSL 283
RV C G G T + R P +D C GTEA +S C LG
Sbjct: 379 RVACREAGC-GPALGATGLGHFGYGRG-----PVLLDNVGCAGTEARLSDCFHLG----- 427
Query: 284 DPMKNVTCENGLPAVVSCVP----GQVFSPDGPSRFR-KAYKPEQPLVRLRGGAYIGEGR 338
C + A C G DG R +P +RL GA+ EGR
Sbjct: 428 --WGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGR 485
Query: 339 VEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGN 398
VE+ WGTVCDD WDL +A V+CR+LG G A A + G G GPI L+ ++C G
Sbjct: 486 VELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGE 545
Query: 399 EKSIIDCK-FNAESQGCNHEEDAGVRC 424
E +++ C ++ C+H EDA V C
Sbjct: 546 ESALLLCSHIRWDAHNCDHSEDASVLC 572
Score = 144 bits (364), Expect = 2e-34
Identities = 120/383 (31%), Positives = 153/383 (39%), Gaps = 85/383 (22%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG----FPGERTYNTKVYKMFASRRKQRYW 259
G +EV G +W +CD W ++ VVC G P R F R
Sbjct: 69 GRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPL------AFGQGRGPILL 122
Query: 260 PFSMDCTGTEAHISSCKLGPQVSLDPMKN----VTCENGLPA-------VVSCVPGQVFS 308
+++C G EA +S C + V C+ LP + S P
Sbjct: 123 D-NVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTL- 180
Query: 309 PDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELG 368
P+G S + VRL GGA + +GRVE+L +G WGTVCDD W L A+VVCR+LG
Sbjct: 181 PNGKS---------EGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLG 231
Query: 369 FGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCK-FNAESQGCNHEEDAGVRC--- 424
G+A A T + G G G I L+ + C G E + C+ C H EDAG C
Sbjct: 232 CGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGL 291
Query: 425 ---------------------------------------NTPAMGLQKK---LRLNGGRN 442
T A KK LRL GG
Sbjct: 292 GPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPG 351
Query: 443 PYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSN 502
P GRVEVL WG VC +W +A V CR+ G G A A T H
Sbjct: 352 PCRGRVEVLHAGG----WGTVCDDDWDFADARVACREAGCGPALGA---TGLGHFGYGRG 404
Query: 503 KVVMSGVKCSGTELSLAHCRHDG 525
V++ V C+GTE L+ C H G
Sbjct: 405 PVLLDNVGCAGTEARLSDCFHLG 427
Score = 139 bits (351), Expect = 8e-33
Identities = 88/245 (35%), Positives = 119/245 (48%), Gaps = 31/245 (12%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
+RL GG GR+EV+ G WG+VCDD WD+V A+VVCR+LG G A GQG
Sbjct: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
Query: 386 GPIHLNEIQCTGNEKSIIDCKFNAES-QGCNHEEDAGVRCN------------------- 425
GPI L+ ++C G E ++ +C C H ED V C+
Sbjct: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
Query: 426 --TPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLG 483
P + +RL GG N +GRVE+L S +WG VC +WG+ +A VVCRQLG G
Sbjct: 178 TTLPNGKSEGSVRLVGGANLCQGRVEIL----HSGLWGTVCDDDWGLPDAAVVCRQLGCG 233
Query: 484 FASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVAC 543
A A ++ +G + +++ V C G E LA C+ G V G AG C
Sbjct: 234 AAMAATTNAFFGYG---TGHILLDNVHCEGGEPRLAACQSLGWGV--HNCGHHEDAGALC 288
Query: 544 SETAP 548
+ P
Sbjct: 289 AGLGP 293
Score = 60.5 bits (145), Expect = 6e-09
Identities = 35/93 (37%), Positives = 51/93 (54%), Gaps = 7/93 (7%)
Query: 433 KKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQET 492
++LRL GG + GR+EV+ GS WG VC +W +V+A VVCRQLG G A +
Sbjct: 56 QELRLVGGPSRCRGRLEVM--HGGS--WGSVCDDDWDVVDANVVCRQLGCGLALPVPRPL 111
Query: 493 WYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525
+ G +++ V+C G E +L+ C G
Sbjct: 112 AFGQG---RGPILLDNVECRGQEAALSECGSRG 141
>gi|20149540 lysyl oxidase preproprotein [Homo sapiens]
Length = 417
Score = 221 bits (562), Expect = 3e-57
Identities = 100/203 (49%), Positives = 139/203 (68%), Gaps = 3/203 (1%)
Query: 548 PDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTT-GYRRLLRFSSQIHNN 606
PDLV + +Q +TY++ M+ L+CA EENCL+++A + D +R LLRF ++ N
Sbjct: 213 PDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQ 272
Query: 607 GQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTK-VAEGHKASFCLEDTECEG 665
G SDF P R++W WH CH+HYHSM+ F+HYDLL+ N + VAEGHKASFCLEDT C+
Sbjct: 273 GTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDY 332
Query: 666 DIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDY 725
+ + C QG++ GC+D Y DIDCQW+DITDV PG+Y+ +V +NP++ V ESDY
Sbjct: 333 GYHRRFACTAH-TQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDY 391
Query: 726 SNNIMKCRSRYDGHRIWMYNCHI 748
+NN+++C RY GH + C I
Sbjct: 392 TNNVVRCDIRYTGHHAYASGCTI 414
>gi|67782346 lysyl oxidase-like 1 preproprotein [Homo sapiens]
Length = 574
Score = 216 bits (550), Expect = 6e-56
Identities = 107/230 (46%), Positives = 143/230 (62%), Gaps = 8/230 (3%)
Query: 525 GEDVACPQGGVQYGAGVACSETA---PDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLS 581
GE QG + G+ ++ PDLV + VQ +TY++ ++ L+CA EE CL
Sbjct: 344 GERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCL- 402
Query: 582 ASAAQTDPTTGY--RRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYD 639
AS A T Y R LLRF ++ N G +DF P RH W WH CH+HYHSM+ F+HYD
Sbjct: 403 ASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYD 462
Query: 640 LLNL-NGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWV 698
LL+ G KVAEGHKASFCLED+ C+ K Y C + QG++ GC+D Y DIDCQW+
Sbjct: 463 LLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSH-TQGLSPGCYDTYNADIDCQWI 521
Query: 699 DITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHI 748
DITDV PG+Y+ +V +NP + V ESD++NN+++C Y G + NC I
Sbjct: 522 DITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKI 571
>gi|44889963 CD163 antigen isoform b [Homo sapiens]
Length = 1121
Score = 213 bits (542), Expect = 5e-55
Identities = 146/478 (30%), Positives = 221/478 (46%), Gaps = 84/478 (17%)
Query: 57 QLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGY---VEAKSWTASSS 113
+LRL + K S GRVEV +WGTVC++ +S+ A V+C +LG ++A W SS+
Sbjct: 50 ELRLVDGENKCS-GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSA 108
Query: 114 YGKGEGPIWLDNLHCTGNEATLAACTSNGWGV-TDCKHTEDVGVVCSDKRIPGFKFDNSL 172
G G IW+D++ C GNE+ L C +GWG ++C H +D GV CSD
Sbjct: 109 ---GSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG----------- 154
Query: 173 INQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVC- 231
NL +++ + + G +E+K W +CD ++ ++ V+C
Sbjct: 155 ----SNLEMRL------------TRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICR 198
Query: 232 -----GMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPM 286
F G + W + C G E+ + +CK
Sbjct: 199 QLECGSAVSFSGSSNF---------GEGSGPIWFDDLICNGNESALWNCK------HQGW 243
Query: 287 KNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGE 346
C++ A V C G S +RL G GR+EV GE
Sbjct: 244 GKHNCDHAEDAGVICSKGADLS-----------------LRLVDGVTECSGRLEVRFQGE 286
Query: 347 WGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCK 406
WGT+CDD WD A+V C++LG +A A+ +G G I L+ + C G+E ++ CK
Sbjct: 287 WGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCK 346
Query: 407 FNAESQG-CNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCG 465
+ + CNH EDAGV C+ G +LRL GG + G VEV ++R + G VC
Sbjct: 347 HHEWGKHYCNHNEDAGVTCSD---GSDLELRLRGGGSRCAGTVEVEIQR----LLGKVCD 399
Query: 466 QNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRH 523
+ WG+ EA VVCRQLG G +A + ++ + + + + C+G E SL C++
Sbjct: 400 RGWGLKEADVVCRQLGCG---SALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKN 454
Score = 207 bits (526), Expect = 4e-53
Identities = 139/425 (32%), Positives = 190/425 (44%), Gaps = 58/425 (13%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVEV + WG++CD DFS+ AA V+CREL S + +G+G G IW + C
Sbjct: 489 GRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCE 548
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIR 189
G+E+ L+ C C H+ DVGVVCS + +IR+
Sbjct: 549 GHESHLSLCPVAPRPEGTCSHSRDVGVVCS----------------------RYTEIRL- 585
Query: 190 AILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMF------GFPGERTYN 243
+TP EG VE+K W +C+ HW +++ V+C PG +
Sbjct: 586 -----VNGKTPC-EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
Query: 244 TKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQ-VSLDPMKNVT---CENGLPAVV 299
+ + W CTGTE H+ C + SL P + V C +
Sbjct: 640 ---------KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTL 690
Query: 300 SCVPGQVFSPDGPSRFRKAYKP--EQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDL 357
S P P+ ++ E +RL G GRVE+ G WGT+CDD WDL
Sbjct: 691 SSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDL 750
Query: 358 VSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNH 416
A VVCR+LG G A A + G+G GPI L+E++C G E I C + Q C H
Sbjct: 751 SDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRH 810
Query: 417 EEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVV 476
+EDAGV C+ + +L R GR+EV NG+ WG V + VV
Sbjct: 811 KEDAGVICSE---FMSLRLTSEASREACAGRLEVFY--NGA--WGTVGKSSMSETTVGVV 863
Query: 477 CRQLG 481
CRQLG
Sbjct: 864 CRQLG 868
Score = 204 bits (519), Expect = 3e-52
Identities = 130/390 (33%), Positives = 173/390 (44%), Gaps = 71/390 (18%)
Query: 42 PEYHQPQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELG 101
P + A A + QLRL + + GRVE+Y++G WGT+CDD + + AHVVCR+LG
Sbjct: 703 PTIPEESAVACIESGQLRLVNGGGRCA-GRVEIYHEGSWGTICDDSWDLSDAHVVCRQLG 761
Query: 102 YVEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDK 161
EA + T S+ +G+G GPIWLD + C G E+ + C S+GWG +C+H ED GV+CS+
Sbjct: 762 CGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSE- 820
Query: 162 RIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKH 221
++ T G +EV W +
Sbjct: 821 --------------------------FMSLRLTSEASREACAGRLEVFYNGAWGTVGKSS 854
Query: 222 WTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQV 281
+ VVC G + N AS K P +D
Sbjct: 855 MSETTVGVVCRQLGCADKGKINP------ASLDKAMSIPMWVD----------------- 891
Query: 282 SLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQP------LVRLRGGAYIG 335
NV C G + C P P R A E+ +RL+ G
Sbjct: 892 ------NVQCPKGPDTLWQC-------PSSPWEKRLASPSEETWITCDNKIRLQEGPTSC 938
Query: 336 EGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQC 395
GRVE+ G WGTVCDD WDL A VVC++LG G A +A + GQG GPI LNE++C
Sbjct: 939 SGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKC 998
Query: 396 TGNEKSIIDCKFNAESQG-CNHEEDAGVRC 424
GNE S+ DC C H+EDA V C
Sbjct: 999 KGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
Score = 203 bits (517), Expect = 4e-52
Identities = 153/492 (31%), Positives = 221/492 (44%), Gaps = 78/492 (15%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GR+E+ + G+WGTVCDD+F+I A V+CR+L A S++ SS++G+G GPIW D+L C
Sbjct: 170 GRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICN 229
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIR 189
GNE+ L C GWG +C H ED GV+CS + D+ +R
Sbjct: 230 GNESALWNCKHQGWGKHNCDHAEDAGVICS----------------------KGADLSLR 267
Query: 190 AILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKM 249
+ G +EV+ W ICD W + ++ V C G P T T + ++
Sbjct: 268 LV-----DGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCP---TAVTAIGRV 319
Query: 250 FASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSP 309
AS+ W S+ C G E + CK C + A V+C G
Sbjct: 320 NASKGFGHIWLDSVSCQGHEPAVWQCK------HHEWGKHYCNHNEDAGVTCSDGSDLE- 372
Query: 310 DGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGF 369
+RLRGG G VEV G VCD W L A VVCR+LG
Sbjct: 373 ----------------LRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGC 416
Query: 370 GSAKEAVTGSRLGQGIGPIH--LNEIQCTGNEKSIIDCKFNAESQG--CNHEEDAGVRCN 425
GSA + T ++ I + L C GNE S+ DCK N + G C+H E+A + C+
Sbjct: 417 GSALK--TSYQVYSKIQATNTWLFLSSCNGNETSLWDCK-NWQWGGLTCDHYEEAKITCS 473
Query: 426 TPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFA 485
++ RL GG P GRVEV ++G WG +C ++ + A V+CR+L G
Sbjct: 474 A-----HREPRLVGGDIPCSGRVEV---KHGD-TWGSICDSDFSLEAASVLCRELQCGTV 524
Query: 486 SNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYG--AGVAC 543
+ + G + ++ +C G E L+ C P+G + GV C
Sbjct: 525 VSILGGAHFGEG---NGQIWAEEFQCEGHESHLSLC----PVAPRPEGTCSHSRDVGVVC 577
Query: 544 SETAPDLVLNAE 555
S ++N +
Sbjct: 578 SRYTEIRLVNGK 589
Score = 202 bits (514), Expect = 1e-51
Identities = 149/493 (30%), Positives = 214/493 (43%), Gaps = 73/493 (14%)
Query: 54 AKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSS 113
A + LRL + S GR+EV + G+WGT+CDD + + A V C++LG A + +
Sbjct: 262 ADLSLRLVDGVTECS-GRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVN 320
Query: 114 YGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLI 173
KG G IWLD++ C G+E + C + WG C H ED GV CSD
Sbjct: 321 ASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDG------------ 368
Query: 174 NQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGM 233
D+ +R R G VEV+ + ++CD+ W K + VVC
Sbjct: 369 ----------SDLELRL-----RGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQ 413
Query: 234 FGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCEN 293
G + +VY + W F C G E + CK L TC++
Sbjct: 414 LGCGSALKTSYQVYSKIQATNT---WLFLSSCNGNETSLWDCKNWQWGGL------TCDH 464
Query: 294 GLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDD 353
A ++C S R+ RL GG GRVEV WG++CD
Sbjct: 465 YEEAKITC-----------SAHREP--------RLVGGDIPCSGRVEVKHGDTWGSICDS 505
Query: 354 KWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQG 413
+ L +ASV+CREL G+ + G+ G+G G I E QC G+E + C +G
Sbjct: 506 DFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEG 565
Query: 414 -CNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVE 472
C+H D GV C+ ++RL G+ P EGRVE+ WG +C +W I +
Sbjct: 566 TCSHSRDVGVVCSR-----YTEIRLVNGKTPCEGRVELKTLG----AWGSLCNSHWDIED 616
Query: 473 AMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVA-CP 531
A V+C+QL G A + + G + ++ C+GTE + C + CP
Sbjct: 617 AHVLCQQLKCGVALSTPGGARFGKG---NGQIWRHMFHCTGTEQHMGDCPVTALGASLCP 673
Query: 532 QGGVQYGAGVACS 544
V A V CS
Sbjct: 674 SEQV---ASVICS 683
Score = 171 bits (434), Expect = 2e-42
Identities = 151/522 (28%), Positives = 215/522 (41%), Gaps = 104/522 (19%)
Query: 56 IQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYG 115
++LRL G + + G VEV G VCD + + A VVCR+LG A T+ Y
Sbjct: 371 LELRLRGGGSRCA-GTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALK-TSYQVYS 428
Query: 116 KGEGP-IWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLIN 174
K + WL C GNE +L C + WG C H E+ + CS R P
Sbjct: 429 KIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP---------- 478
Query: 175 QIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMF 234
+ DI G VEVK G TW ICD ++ + + V+C
Sbjct: 479 -----RLVGGDIPC--------------SGRVEVKHGDTWGSICDSDFSLEAASVLCR-- 517
Query: 235 GFPGERTYNTKVYKMFASRRKQ---RYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTC 291
E T V + + + + W C G E+H+S C + P+ TC
Sbjct: 518 ----ELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPR------PEGTC 567
Query: 292 ENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVC 351
+ V C SR+ + +RL G EGRVE+ G WG++C
Sbjct: 568 SHSRDVGVVC-----------SRYTE--------IRLVNGKTPCEGRVELKTLGAWGSLC 608
Query: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAES 411
+ WD+ A V+C++L G A G+R G+G G I + CTG E+ + DC A
Sbjct: 609 NSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALG 668
Query: 412 QG-CNHEEDAGV-----------RCNTPAMGLQK---------------KLRLNGGRNPY 444
C E+ A V CN+ ++G + +LRL G
Sbjct: 669 ASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRC 728
Query: 445 EGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKV 504
GRVE+ E + WG +C +W + +A VVCRQLG G A NA + G + +
Sbjct: 729 AGRVEIYHEGS----WGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEG---TGPI 781
Query: 505 VMSGVKCSGTELSLAHCR-HDGEDVACPQGGVQYGAGVACSE 545
+ +KC+G E + C H C + AGV CSE
Sbjct: 782 WLDEMKCNGKESRIWQCHSHGWGQQNCRH---KEDAGVICSE 820
Score = 155 bits (392), Expect = 1e-37
Identities = 137/479 (28%), Positives = 197/479 (41%), Gaps = 66/479 (13%)
Query: 57 QLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGK 116
++RL K EGRVE+ G WG++C+ + I AHV+C++L A S + +GK
Sbjct: 582 EIRLVNGKTP-CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGK 640
Query: 117 GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSL---- 172
G G IW HCTG E + C G + C + V+CS + NS
Sbjct: 641 GNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGP 700
Query: 173 ---INQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRV 229
E+ +E ++R + R G VE+ +W ICD W ++ V
Sbjct: 701 TRPTIPEESAVACIESGQLRLVNGGGR-----CAGRVEIYHEGSWGTICDDSWDLSDAHV 755
Query: 230 VCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKL---GPQVSLDPM 286
VC G GE T W M C G E+ I C G Q
Sbjct: 756 VCRQLGC-GEAINATG--SAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQ------ 806
Query: 287 KNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAY--IGEGRVEVLKN 344
C + A V C S F +RL A GR+EV N
Sbjct: 807 ---NCRHKEDAGVIC-----------SEFMS--------LRLTSEASREACAGRLEVFYN 844
Query: 345 GEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIG-PIHLNEIQCTGNEKSII 403
G WGTV + VVCR+LG K + + L + + P+ ++ +QC ++
Sbjct: 845 GAWGTVGKSSMSETTVGVVCRQLGCAD-KGKINPASLDKAMSIPMWVDNVQCPKGPDTLW 903
Query: 404 DCKFNA-ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGM 462
C + E + + E+ + C+ K+RL G GRVE+ GS WG
Sbjct: 904 QCPSSPWEKRLASPSEETWITCDN-------KIRLQEGPTSCSGRVEIW--HGGS--WGT 952
Query: 463 VCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHC 521
VC +W + +A VVC+QLG G A AF+E + G + + ++ VKC G E SL C
Sbjct: 953 VCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQG---TGPIWLNEVKCKGNESSLWDC 1008
Score = 149 bits (377), Expect = 7e-36
Identities = 108/352 (30%), Positives = 153/352 (43%), Gaps = 56/352 (15%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G VEVK + W +C+ W+ + V+C G P T +S R W +
Sbjct: 62 GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCP---TAIKAPGWANSSAGSGRIWMDHV 118
Query: 264 DCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQ 323
C G E+ + CK K+ C + A V+C G
Sbjct: 119 SCRGNESALWDCKHDGWG-----KHSNCTHQQDAGVTCSDGSNLE--------------- 158
Query: 324 PLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQ 383
+RL G + GR+E+ G WGTVCDD +++ ASV+CR+L GSA S G+
Sbjct: 159 --MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGE 216
Query: 384 GIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRN 442
G GPI +++ C GNE ++ +CK C+H EDAGV C + G LRL G
Sbjct: 217 GSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVIC---SKGADLSLRLVDGVT 273
Query: 443 PYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSN 502
GR+EV + WG +C W +A V C+QLG A A G VN++
Sbjct: 274 ECSGRLEVRFQGE----WGTICDDGWDSYDAAVACKQLGCPTAVTAI-------GRVNAS 322
Query: 503 K----VVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQY-----GAGVACSE 545
K + + V C G E ++ C+H + G Y AGV CS+
Sbjct: 323 KGFGHIWLDSVSCQGHEPAVWQCKHH-------EWGKHYCNHNEDAGVTCSD 367
Score = 123 bits (309), Expect = 6e-28
Identities = 70/202 (34%), Positives = 106/202 (52%), Gaps = 12/202 (5%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
+RL G GRVEV EWGTVC++ W + + SV+C +LG +A +A + G
Sbjct: 51 LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
Query: 386 GPIHLNEIQCTGNEKSIIDCKFN--AESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNP 443
G I ++ + C GNE ++ DCK + + C H++DAGV C+ G ++RL G N
Sbjct: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSD---GSNLEMRLTRGGNM 167
Query: 444 YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503
GR+E+ + WG VC N+ I A V+CRQL G A + + + G S
Sbjct: 168 CSGRIEIKFQGR----WGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEG---SGP 220
Query: 504 VVMSGVKCSGTELSLAHCRHDG 525
+ + C+G E +L +C+H G
Sbjct: 221 IWFDDLICNGNESALWNCKHQG 242
Score = 98.6 bits (244), Expect = 2e-20
Identities = 41/91 (45%), Positives = 59/91 (64%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVE+++ G WGTVCDD + + A VVC++LG A + +G+G GPIWL+ + C
Sbjct: 940 GRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCK 999
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSD 160
GNE++L C + WG ++C H ED V C+D
Sbjct: 1000 GNESSLWDCPARRWGHSECGHKEDAAVNCTD 1030
Score = 70.9 bits (172), Expect = 4e-12
Identities = 76/282 (26%), Positives = 110/282 (39%), Gaps = 37/282 (13%)
Query: 430 GLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAF 489
G K+LRL G N GRVEV V+ WG VC W + V+C QLG A
Sbjct: 46 GTDKELRLVDGENKCSGRVEVKVQEE----WGTVCNNGWSMEAVSVICNQLG---CPTAI 98
Query: 490 QETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHD--GEDVACPQGGVQYGAGVACSETA 547
+ + + S ++ M V C G E +L C+HD G+ C Q AGV CS+ +
Sbjct: 99 KAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH---QQDAGVTCSDGS 155
Query: 548 PDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTGYRRLLRFSSQIHNNG 607
L + + R Q C D + R L S + +G
Sbjct: 156 N---LEMRLTRGGNMCSGRIEIKFQGRWGTVC--DDNFNIDHASVICRQLECGSAVSFSG 210
Query: 608 QSDFRPKNGRHAWIWHD---CHRHYHSMEVFTHY-------DLLNLNGTKVAEGHKASFC 657
S+F +G IW D C+ + ++ H D G ++G S
Sbjct: 211 SSNFGEGSGP---IWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLR 267
Query: 658 LED--TECEGDIQKNYECANFGDQG-ITMGCWDMYRHDIDCQ 696
L D TEC G ++ ++ G+ G I WD Y + C+
Sbjct: 268 LVDGVTECSGRLEVRFQ----GEWGTICDDGWDSYDAAVACK 305
>gi|44662834 CD163 antigen isoform a [Homo sapiens]
Length = 1156
Score = 213 bits (542), Expect = 5e-55
Identities = 146/478 (30%), Positives = 221/478 (46%), Gaps = 84/478 (17%)
Query: 57 QLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGY---VEAKSWTASSS 113
+LRL + K S GRVEV +WGTVC++ +S+ A V+C +LG ++A W SS+
Sbjct: 50 ELRLVDGENKCS-GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSA 108
Query: 114 YGKGEGPIWLDNLHCTGNEATLAACTSNGWGV-TDCKHTEDVGVVCSDKRIPGFKFDNSL 172
G G IW+D++ C GNE+ L C +GWG ++C H +D GV CSD
Sbjct: 109 ---GSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG----------- 154
Query: 173 INQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVC- 231
NL +++ + + G +E+K W +CD ++ ++ V+C
Sbjct: 155 ----SNLEMRL------------TRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICR 198
Query: 232 -----GMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPM 286
F G + W + C G E+ + +CK
Sbjct: 199 QLECGSAVSFSGSSNF---------GEGSGPIWFDDLICNGNESALWNCK------HQGW 243
Query: 287 KNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGE 346
C++ A V C G S +RL G GR+EV GE
Sbjct: 244 GKHNCDHAEDAGVICSKGADLS-----------------LRLVDGVTECSGRLEVRFQGE 286
Query: 347 WGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCK 406
WGT+CDD WD A+V C++LG +A A+ +G G I L+ + C G+E ++ CK
Sbjct: 287 WGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCK 346
Query: 407 FNAESQG-CNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCG 465
+ + CNH EDAGV C+ G +LRL GG + G VEV ++R + G VC
Sbjct: 347 HHEWGKHYCNHNEDAGVTCSD---GSDLELRLRGGGSRCAGTVEVEIQR----LLGKVCD 399
Query: 466 QNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRH 523
+ WG+ EA VVCRQLG G +A + ++ + + + + C+G E SL C++
Sbjct: 400 RGWGLKEADVVCRQLGCG---SALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKN 454
Score = 207 bits (526), Expect = 4e-53
Identities = 139/425 (32%), Positives = 190/425 (44%), Gaps = 58/425 (13%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVEV + WG++CD DFS+ AA V+CREL S + +G+G G IW + C
Sbjct: 489 GRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCE 548
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIR 189
G+E+ L+ C C H+ DVGVVCS + +IR+
Sbjct: 549 GHESHLSLCPVAPRPEGTCSHSRDVGVVCS----------------------RYTEIRL- 585
Query: 190 AILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMF------GFPGERTYN 243
+TP EG VE+K W +C+ HW +++ V+C PG +
Sbjct: 586 -----VNGKTPC-EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
Query: 244 TKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQ-VSLDPMKNVT---CENGLPAVV 299
+ + W CTGTE H+ C + SL P + V C +
Sbjct: 640 ---------KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTL 690
Query: 300 SCVPGQVFSPDGPSRFRKAYKP--EQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDL 357
S P P+ ++ E +RL G GRVE+ G WGT+CDD WDL
Sbjct: 691 SSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDL 750
Query: 358 VSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNH 416
A VVCR+LG G A A + G+G GPI L+E++C G E I C + Q C H
Sbjct: 751 SDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRH 810
Query: 417 EEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVV 476
+EDAGV C+ + +L R GR+EV NG+ WG V + VV
Sbjct: 811 KEDAGVICSE---FMSLRLTSEASREACAGRLEVFY--NGA--WGTVGKSSMSETTVGVV 863
Query: 477 CRQLG 481
CRQLG
Sbjct: 864 CRQLG 868
Score = 204 bits (519), Expect = 3e-52
Identities = 130/390 (33%), Positives = 173/390 (44%), Gaps = 71/390 (18%)
Query: 42 PEYHQPQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELG 101
P + A A + QLRL + + GRVE+Y++G WGT+CDD + + AHVVCR+LG
Sbjct: 703 PTIPEESAVACIESGQLRLVNGGGRCA-GRVEIYHEGSWGTICDDSWDLSDAHVVCRQLG 761
Query: 102 YVEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDK 161
EA + T S+ +G+G GPIWLD + C G E+ + C S+GWG +C+H ED GV+CS+
Sbjct: 762 CGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSE- 820
Query: 162 RIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKH 221
++ T G +EV W +
Sbjct: 821 --------------------------FMSLRLTSEASREACAGRLEVFYNGAWGTVGKSS 854
Query: 222 WTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQV 281
+ VVC G + N AS K P +D
Sbjct: 855 MSETTVGVVCRQLGCADKGKINP------ASLDKAMSIPMWVD----------------- 891
Query: 282 SLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQP------LVRLRGGAYIG 335
NV C G + C P P R A E+ +RL+ G
Sbjct: 892 ------NVQCPKGPDTLWQC-------PSSPWEKRLASPSEETWITCDNKIRLQEGPTSC 938
Query: 336 EGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQC 395
GRVE+ G WGTVCDD WDL A VVC++LG G A +A + GQG GPI LNE++C
Sbjct: 939 SGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKC 998
Query: 396 TGNEKSIIDCKFNAESQG-CNHEEDAGVRC 424
GNE S+ DC C H+EDA V C
Sbjct: 999 KGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
Score = 203 bits (517), Expect = 4e-52
Identities = 153/492 (31%), Positives = 221/492 (44%), Gaps = 78/492 (15%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GR+E+ + G+WGTVCDD+F+I A V+CR+L A S++ SS++G+G GPIW D+L C
Sbjct: 170 GRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICN 229
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIR 189
GNE+ L C GWG +C H ED GV+CS + D+ +R
Sbjct: 230 GNESALWNCKHQGWGKHNCDHAEDAGVICS----------------------KGADLSLR 267
Query: 190 AILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKM 249
+ G +EV+ W ICD W + ++ V C G P T T + ++
Sbjct: 268 LV-----DGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCP---TAVTAIGRV 319
Query: 250 FASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSP 309
AS+ W S+ C G E + CK C + A V+C G
Sbjct: 320 NASKGFGHIWLDSVSCQGHEPAVWQCK------HHEWGKHYCNHNEDAGVTCSDGSDLE- 372
Query: 310 DGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGF 369
+RLRGG G VEV G VCD W L A VVCR+LG
Sbjct: 373 ----------------LRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGC 416
Query: 370 GSAKEAVTGSRLGQGIGPIH--LNEIQCTGNEKSIIDCKFNAESQG--CNHEEDAGVRCN 425
GSA + T ++ I + L C GNE S+ DCK N + G C+H E+A + C+
Sbjct: 417 GSALK--TSYQVYSKIQATNTWLFLSSCNGNETSLWDCK-NWQWGGLTCDHYEEAKITCS 473
Query: 426 TPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFA 485
++ RL GG P GRVEV ++G WG +C ++ + A V+CR+L G
Sbjct: 474 A-----HREPRLVGGDIPCSGRVEV---KHGD-TWGSICDSDFSLEAASVLCRELQCGTV 524
Query: 486 SNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYG--AGVAC 543
+ + G + ++ +C G E L+ C P+G + GV C
Sbjct: 525 VSILGGAHFGEG---NGQIWAEEFQCEGHESHLSLC----PVAPRPEGTCSHSRDVGVVC 577
Query: 544 SETAPDLVLNAE 555
S ++N +
Sbjct: 578 SRYTEIRLVNGK 589
Score = 202 bits (514), Expect = 1e-51
Identities = 149/493 (30%), Positives = 214/493 (43%), Gaps = 73/493 (14%)
Query: 54 AKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSS 113
A + LRL + S GR+EV + G+WGT+CDD + + A V C++LG A + +
Sbjct: 262 ADLSLRLVDGVTECS-GRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVN 320
Query: 114 YGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLI 173
KG G IWLD++ C G+E + C + WG C H ED GV CSD
Sbjct: 321 ASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDG------------ 368
Query: 174 NQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGM 233
D+ +R R G VEV+ + ++CD+ W K + VVC
Sbjct: 369 ----------SDLELRL-----RGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQ 413
Query: 234 FGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCEN 293
G + +VY + W F C G E + CK L TC++
Sbjct: 414 LGCGSALKTSYQVYSKIQATNT---WLFLSSCNGNETSLWDCKNWQWGGL------TCDH 464
Query: 294 GLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDD 353
A ++C S R+ RL GG GRVEV WG++CD
Sbjct: 465 YEEAKITC-----------SAHREP--------RLVGGDIPCSGRVEVKHGDTWGSICDS 505
Query: 354 KWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQG 413
+ L +ASV+CREL G+ + G+ G+G G I E QC G+E + C +G
Sbjct: 506 DFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEG 565
Query: 414 -CNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVE 472
C+H D GV C+ ++RL G+ P EGRVE+ WG +C +W I +
Sbjct: 566 TCSHSRDVGVVCSR-----YTEIRLVNGKTPCEGRVELKTLG----AWGSLCNSHWDIED 616
Query: 473 AMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVA-CP 531
A V+C+QL G A + + G + ++ C+GTE + C + CP
Sbjct: 617 AHVLCQQLKCGVALSTPGGARFGKG---NGQIWRHMFHCTGTEQHMGDCPVTALGASLCP 673
Query: 532 QGGVQYGAGVACS 544
V A V CS
Sbjct: 674 SEQV---ASVICS 683
Score = 171 bits (434), Expect = 2e-42
Identities = 151/522 (28%), Positives = 215/522 (41%), Gaps = 104/522 (19%)
Query: 56 IQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYG 115
++LRL G + + G VEV G VCD + + A VVCR+LG A T+ Y
Sbjct: 371 LELRLRGGGSRCA-GTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALK-TSYQVYS 428
Query: 116 KGEGP-IWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLIN 174
K + WL C GNE +L C + WG C H E+ + CS R P
Sbjct: 429 KIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP---------- 478
Query: 175 QIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMF 234
+ DI G VEVK G TW ICD ++ + + V+C
Sbjct: 479 -----RLVGGDIPC--------------SGRVEVKHGDTWGSICDSDFSLEAASVLCR-- 517
Query: 235 GFPGERTYNTKVYKMFASRRKQ---RYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTC 291
E T V + + + + W C G E+H+S C + P+ TC
Sbjct: 518 ----ELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPR------PEGTC 567
Query: 292 ENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVC 351
+ V C SR+ + +RL G EGRVE+ G WG++C
Sbjct: 568 SHSRDVGVVC-----------SRYTE--------IRLVNGKTPCEGRVELKTLGAWGSLC 608
Query: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAES 411
+ WD+ A V+C++L G A G+R G+G G I + CTG E+ + DC A
Sbjct: 609 NSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALG 668
Query: 412 QG-CNHEEDAGV-----------RCNTPAMGLQK---------------KLRLNGGRNPY 444
C E+ A V CN+ ++G + +LRL G
Sbjct: 669 ASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRC 728
Query: 445 EGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKV 504
GRVE+ E + WG +C +W + +A VVCRQLG G A NA + G + +
Sbjct: 729 AGRVEIYHEGS----WGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEG---TGPI 781
Query: 505 VMSGVKCSGTELSLAHCR-HDGEDVACPQGGVQYGAGVACSE 545
+ +KC+G E + C H C + AGV CSE
Sbjct: 782 WLDEMKCNGKESRIWQCHSHGWGQQNCRH---KEDAGVICSE 820
Score = 155 bits (392), Expect = 1e-37
Identities = 137/479 (28%), Positives = 197/479 (41%), Gaps = 66/479 (13%)
Query: 57 QLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGK 116
++RL K EGRVE+ G WG++C+ + I AHV+C++L A S + +GK
Sbjct: 582 EIRLVNGKTP-CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGK 640
Query: 117 GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSL---- 172
G G IW HCTG E + C G + C + V+CS + NS
Sbjct: 641 GNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGP 700
Query: 173 ---INQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRV 229
E+ +E ++R + R G VE+ +W ICD W ++ V
Sbjct: 701 TRPTIPEESAVACIESGQLRLVNGGGR-----CAGRVEIYHEGSWGTICDDSWDLSDAHV 755
Query: 230 VCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKL---GPQVSLDPM 286
VC G GE T W M C G E+ I C G Q
Sbjct: 756 VCRQLGC-GEAINATG--SAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQ------ 806
Query: 287 KNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAY--IGEGRVEVLKN 344
C + A V C S F +RL A GR+EV N
Sbjct: 807 ---NCRHKEDAGVIC-----------SEFMS--------LRLTSEASREACAGRLEVFYN 844
Query: 345 GEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIG-PIHLNEIQCTGNEKSII 403
G WGTV + VVCR+LG K + + L + + P+ ++ +QC ++
Sbjct: 845 GAWGTVGKSSMSETTVGVVCRQLGCAD-KGKINPASLDKAMSIPMWVDNVQCPKGPDTLW 903
Query: 404 DCKFNA-ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGM 462
C + E + + E+ + C+ K+RL G GRVE+ GS WG
Sbjct: 904 QCPSSPWEKRLASPSEETWITCDN-------KIRLQEGPTSCSGRVEIW--HGGS--WGT 952
Query: 463 VCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHC 521
VC +W + +A VVC+QLG G A AF+E + G + + ++ VKC G E SL C
Sbjct: 953 VCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQG---TGPIWLNEVKCKGNESSLWDC 1008
Score = 149 bits (377), Expect = 7e-36
Identities = 108/352 (30%), Positives = 153/352 (43%), Gaps = 56/352 (15%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G VEVK + W +C+ W+ + V+C G P T +S R W +
Sbjct: 62 GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCP---TAIKAPGWANSSAGSGRIWMDHV 118
Query: 264 DCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQ 323
C G E+ + CK K+ C + A V+C G
Sbjct: 119 SCRGNESALWDCKHDGWG-----KHSNCTHQQDAGVTCSDGSNLE--------------- 158
Query: 324 PLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQ 383
+RL G + GR+E+ G WGTVCDD +++ ASV+CR+L GSA S G+
Sbjct: 159 --MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGE 216
Query: 384 GIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRN 442
G GPI +++ C GNE ++ +CK C+H EDAGV C + G LRL G
Sbjct: 217 GSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVIC---SKGADLSLRLVDGVT 273
Query: 443 PYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSN 502
GR+EV + WG +C W +A V C+QLG A A G VN++
Sbjct: 274 ECSGRLEVRFQGE----WGTICDDGWDSYDAAVACKQLGCPTAVTAI-------GRVNAS 322
Query: 503 K----VVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQY-----GAGVACSE 545
K + + V C G E ++ C+H + G Y AGV CS+
Sbjct: 323 KGFGHIWLDSVSCQGHEPAVWQCKHH-------EWGKHYCNHNEDAGVTCSD 367
Score = 123 bits (309), Expect = 6e-28
Identities = 70/202 (34%), Positives = 106/202 (52%), Gaps = 12/202 (5%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
+RL G GRVEV EWGTVC++ W + + SV+C +LG +A +A + G
Sbjct: 51 LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
Query: 386 GPIHLNEIQCTGNEKSIIDCKFN--AESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNP 443
G I ++ + C GNE ++ DCK + + C H++DAGV C+ G ++RL G N
Sbjct: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSD---GSNLEMRLTRGGNM 167
Query: 444 YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503
GR+E+ + WG VC N+ I A V+CRQL G A + + + G S
Sbjct: 168 CSGRIEIKFQGR----WGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEG---SGP 220
Query: 504 VVMSGVKCSGTELSLAHCRHDG 525
+ + C+G E +L +C+H G
Sbjct: 221 IWFDDLICNGNESALWNCKHQG 242
Score = 98.6 bits (244), Expect = 2e-20
Identities = 41/91 (45%), Positives = 59/91 (64%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVE+++ G WGTVCDD + + A VVC++LG A + +G+G GPIWL+ + C
Sbjct: 940 GRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCK 999
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSD 160
GNE++L C + WG ++C H ED V C+D
Sbjct: 1000 GNESSLWDCPARRWGHSECGHKEDAAVNCTD 1030
Score = 70.9 bits (172), Expect = 4e-12
Identities = 76/282 (26%), Positives = 110/282 (39%), Gaps = 37/282 (13%)
Query: 430 GLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAF 489
G K+LRL G N GRVEV V+ WG VC W + V+C QLG A
Sbjct: 46 GTDKELRLVDGENKCSGRVEVKVQEE----WGTVCNNGWSMEAVSVICNQLG---CPTAI 98
Query: 490 QETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHD--GEDVACPQGGVQYGAGVACSETA 547
+ + + S ++ M V C G E +L C+HD G+ C Q AGV CS+ +
Sbjct: 99 KAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH---QQDAGVTCSDGS 155
Query: 548 PDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTGYRRLLRFSSQIHNNG 607
L + + R Q C D + R L S + +G
Sbjct: 156 N---LEMRLTRGGNMCSGRIEIKFQGRWGTVC--DDNFNIDHASVICRQLECGSAVSFSG 210
Query: 608 QSDFRPKNGRHAWIWHD---CHRHYHSMEVFTHY-------DLLNLNGTKVAEGHKASFC 657
S+F +G IW D C+ + ++ H D G ++G S
Sbjct: 211 SSNFGEGSGP---IWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLR 267
Query: 658 LED--TECEGDIQKNYECANFGDQG-ITMGCWDMYRHDIDCQ 696
L D TEC G ++ ++ G+ G I WD Y + C+
Sbjct: 268 LVDGVTECSGRLEVRFQ----GEWGTICDDGWDSYDAAVACK 305
>gi|4506143 neurotrypsin precursor [Homo sapiens]
Length = 875
Score = 211 bits (537), Expect = 2e-54
Identities = 131/370 (35%), Positives = 178/370 (48%), Gaps = 51/370 (13%)
Query: 58 LRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVE-AKSWTASSSYGK 116
+RLAG H EGRVE+Y+ GQWGTVCDD + A V+CR+LG AK+W + +G+
Sbjct: 280 IRLAGGSSVH-EGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWH-QAYFGE 337
Query: 117 GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQI 176
G GP+ LD + CTGNE ++ C + WG +C H ED GV C+ L + +
Sbjct: 338 GSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTP-----------LTDGV 386
Query: 177 ENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF 236
IR+ ++ EG +EV W +CD WT N+ VVC GF
Sbjct: 387 ---------IRLAGGKGSH-------EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGF 430
Query: 237 PGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296
Y + W + C+G E C D C +
Sbjct: 431 K----YGKQASANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHD------CSHRED 480
Query: 297 AVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWD 356
++C PG G P VRL G EGRVEV NG+WGT+CDD W
Sbjct: 481 VSIACYPG------GEGHRLSLGFP----VRLMDGENKKEGRVEVFINGQWGTICDDGWT 530
Query: 357 LVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDC-KFNAESQGCN 415
A+V+CR+LG+ A T + G+G GPIH++ ++CTGNE+S+ DC K + C
Sbjct: 531 DKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCR 590
Query: 416 HEEDAGVRCN 425
H EDAGV C+
Sbjct: 591 HSEDAGVICD 600
Score = 194 bits (492), Expect = 3e-49
Identities = 148/477 (31%), Positives = 200/477 (41%), Gaps = 80/477 (16%)
Query: 58 LRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKG 117
+RL G K + EG VEVY G WGTVC + A V+C +L + G G
Sbjct: 170 VRLRGGKNEF-EGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
Query: 118 EGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIE 177
PI+ N+ C G+E + C + W C V CS P F
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPI--------- 279
Query: 178 NLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFP 237
IR+ + V EG VE+ W +CD W ++ V+C G
Sbjct: 280 --------IRLAG-------GSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLS 324
Query: 238 GERTYNTKVYKMFASRRKQRYW-----PFSMD---CTGTEAHISSCKLGPQVSLDPMKNV 289
G A Q Y+ P +D CTG E I C P+ S
Sbjct: 325 G-----------IAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQC---PKSS---WGEH 367
Query: 290 TCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGT 349
C + A VSC P DG ++RL GG EGR+EV G+WGT
Sbjct: 368 NCGHKEDAGVSCTP----LTDG-------------VIRLAGGKGSHEGRLEVYYRGQWGT 410
Query: 350 VCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA 409
VCDD W ++ VVCR+LGF K+A + + + GPI L+++ C+G E + C
Sbjct: 411 VCDDGWTELNTYVVCRQLGFKYGKQA-SANHFEESTGPIWLDDVSCSGKETRFLQCSRRQ 469
Query: 410 ESQ-GCNHEEDAGVRCNTPAMGLQKKL----RLNGGRNPYEGRVEVLVERNGSLVWGMVC 464
+ C+H ED + C G + L RL G N EGRVEV + NG WG +C
Sbjct: 470 WGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFI--NGQ--WGTIC 525
Query: 465 GQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHC 521
W +A V+CRQLG + A ++ G + + VKC+G E SLA C
Sbjct: 526 DDGWTDKDAAVICRQLGYKGPARARTMAYFGEG---KGPIHVDNVKCTGNERSLADC 579
Score = 179 bits (454), Expect = 9e-45
Identities = 117/344 (34%), Positives = 161/344 (46%), Gaps = 46/344 (13%)
Query: 203 EGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFS 262
EG VEV W +C HW ++ V+C G+ + YW +
Sbjct: 180 EGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLI--PIYWS-N 236
Query: 263 MDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPE 322
+ C G E +I C+ D + C + A V+C FS + P
Sbjct: 237 VRCRGDEENILLCEK------DIWQGGVCPQKMAAAVTCS----FS----------HGPT 276
Query: 323 QPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLG 382
P++RL GG+ + EGRVE+ G+WGTVCDD+WD A V+CR+LG +A + G
Sbjct: 277 FPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFG 336
Query: 383 QGIGPIHLNEIQCTGNEKSIIDC-KFNAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGR 441
+G GP+ L+E++CTGNE SI C K + C H+EDAGV C G+ +RL GG+
Sbjct: 337 EGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGV---IRLAGGK 393
Query: 442 NPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNS 501
+EGR+EV WG VC W + VVCRQLG + A H + ++
Sbjct: 394 GSHEGRLEVYYRGQ----WGTVCDDGWTELNTYVVCRQLGFKYGKQASAN----HFEEST 445
Query: 502 NKVVMSGVKCSGTELSLAHC------RHD---GEDV--ACPQGG 534
+ + V CSG E C RHD EDV AC GG
Sbjct: 446 GPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGG 489
Score = 127 bits (319), Expect = 4e-29
Identities = 79/221 (35%), Positives = 116/221 (52%), Gaps = 12/221 (5%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
VRLRGG EG VEV +G WGTVC WD ASV+C +L G A G G+
Sbjct: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229
Query: 386 GPIHLNEIQCTGNEKSIIDCKFNAESQG-CNHEEDAGVRCNTPAMGLQKKLRLNGGRNPY 444
PI+ + ++C G+E++I+ C+ + G C + A V C+ +RL GG + +
Sbjct: 230 IPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVH 289
Query: 445 EGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKV 504
EGRVE+ WG VC W +A V+CRQLGL + A+ + ++ G S V
Sbjct: 290 EGRVELYHAGQ----WGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEG---SGPV 342
Query: 505 VMSGVKCSGTELSLAHC-RHDGEDVACPQGGVQYGAGVACS 544
++ V+C+G ELS+ C + + C G + AGV+C+
Sbjct: 343 MLDEVRCTGNELSIEQCPKSSWGEHNC---GHKEDAGVSCT 380
Score = 103 bits (258), Expect = 5e-22
Identities = 57/173 (32%), Positives = 93/173 (53%), Gaps = 17/173 (9%)
Query: 62 GQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPI 121
G+ +K EGRVEV+ +GQWGT+CDD ++ A V+CR+LGY + +G+G+GPI
Sbjct: 505 GENKK--EGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPI 562
Query: 122 WLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCS--DKRIPGFKFDNSLINQIENL 179
+DN+ CTGNE +LA C G +C+H+ED GV+C K+ G SL +
Sbjct: 563 HVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSS----- 617
Query: 180 NIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCG 232
+ + +R++ ++ G ++ G W+ + + R++CG
Sbjct: 618 --------VCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCG 662
>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
sapiens]
Length = 1453
Score = 206 bits (525), Expect = 5e-53
Identities = 154/486 (31%), Positives = 209/486 (43%), Gaps = 95/486 (19%)
Query: 56 IQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYG 115
++LRL G + GRVE+ G+WGTVC ++ AA VVC++LG A +
Sbjct: 260 LELRLVGGTNR-CMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQ 318
Query: 116 KGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQ 175
G +WLD + C+GNE+ L C +G DC H DV V+CSD G + L +
Sbjct: 319 SGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSD----GADLELRLADG 374
Query: 176 IENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG 235
N + G VEV+ + W ICD++W + + VVC G
Sbjct: 375 SNNCS-----------------------GRVEVRIHEQWWTICDQNWKNEQALVVCKQLG 411
Query: 236 FPGERTYNTKVYKMFASRR------KQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNV 289
P + +F SRR + W S+ CTG E+ + C + D
Sbjct: 412 CP---------FSVFGSRRAKPSNEARDIWINSISCTGNESALWDC------TYDGKAKR 456
Query: 290 TCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGT 349
TC A V C + K + L RL G GR+EV GEWGT
Sbjct: 457 TCFRRSDAGVIC----------------SDKADLDL-RLVGAHSPCYGRLEVKYQGEWGT 499
Query: 350 VCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA 409
VC D+W +A+VVC++LG G + + GPI L+++ C GNE +I DC+ +
Sbjct: 500 VCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSG 559
Query: 410 -ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNW 468
C H ED V C+ A LRL GG N GR+EV + WG VC W
Sbjct: 560 WGKHNCVHREDVIVTCSGDATW---GLRLVGGSNRCSGRLEVYFQGR----WGTVCDDGW 612
Query: 469 GIVEAMVVCRQL---------GLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLA 519
A VVC QL GLG AS + + W + V C G E L
Sbjct: 613 NSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIW------------LDDVSCDGDESDLW 660
Query: 520 HCRHDG 525
CR+ G
Sbjct: 661 SCRNSG 666
Score = 206 bits (525), Expect = 5e-53
Identities = 131/377 (34%), Positives = 180/377 (47%), Gaps = 71/377 (18%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVE+Y+DG WGT+CDD + + AHVVC++LG A + T S+ +G+G GPIWLD+L+CT
Sbjct: 1047 GRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCT 1106
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIR 189
G E+ L C S GWG DC+H ED GV+CS+
Sbjct: 1107 GMESHLWQCPSRGWGQHDCRHKEDAGVICSE---------------------------FT 1139
Query: 190 AILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKM 249
A+ T G +EV TW + ++ T + +VC G GE N V
Sbjct: 1140 ALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGC-GE---NGVVSLA 1195
Query: 250 FASRRKQRY-WPFSMDCTGTEAHISSCKLGP---QVSLDPMKN-VTCENGLPAVVSCVPG 304
S+ + W + C T I C P ++S + +TCE+
Sbjct: 1196 PLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDR---------- 1245
Query: 305 QVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVC 364
+R+RGG GRVE+ G WGTVCDD WDL A VVC
Sbjct: 1246 ---------------------IRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVC 1284
Query: 365 RELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQG-CNHEEDAGVR 423
++LG GSA A+ + GQG G I L++++C GNE + DC Q C H+EDAGVR
Sbjct: 1285 QQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVR 1344
Query: 424 CNTPAMGLQKKLRLNGG 440
C+ ++ K L + G
Sbjct: 1345 CSGQSL---KSLNASSG 1358
Score = 203 bits (517), Expect = 4e-52
Identities = 153/506 (30%), Positives = 216/506 (42%), Gaps = 85/506 (16%)
Query: 52 NVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTAS 111
N ++LRL S G VEV + GQWGTVCDD ++ A+ VVC++LG + +
Sbjct: 42 NGTDLELRLVNGDGPCS-GTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRF 100
Query: 112 SSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNS 171
G IWLD++ C GNE+ L C WG +C H EDVGV C +
Sbjct: 101 GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEA--------- 151
Query: 172 LINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVC 231
NL +++ D G VEVK + W ICD W + VVC
Sbjct: 152 ------NLGLRLVD------------GNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVC 193
Query: 232 GMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTC 291
G P + V R W + C G E + +C+ + D C
Sbjct: 194 RQLGCPSSFISSGVVNSPAVLRP---IWLDDILCQGNELALWNCRHRGWGNHD------C 244
Query: 292 ENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVC 351
+ ++C Y +RL GG GRVE+ G WGTVC
Sbjct: 245 SHNEDVTLTC-----------------YDSSDLELRLVGGTNRCMGRVELKIQGRWGTVC 287
Query: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAES 411
KW+ +A VVC++LG G+A L G + L+ + C+GNE + DC+ +
Sbjct: 288 HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347
Query: 412 Q-GCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGI 470
C H+ D V C+ G +LRL G N GRVEV + W +C QNW
Sbjct: 348 NFDCLHQNDVSVICSD---GADLELRLADGSNNCSGRVEVRIHEQ----WWTICDQNWKN 400
Query: 471 VEAMVVCRQLGLGFA---------SNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHC 521
+A+VVC+QLG F+ SN ++ W ++ + C+G E +L C
Sbjct: 401 EQALVVCKQLGCPFSVFGSRRAKPSNEARDIW------------INSISCTGNESALWDC 448
Query: 522 RHDGEDVACPQGGVQYGAGVACSETA 547
+DG+ A + AGV CS+ A
Sbjct: 449 TYDGK--AKRTCFRRSDAGVICSDKA 472
Score = 196 bits (498), Expect = 7e-50
Identities = 147/489 (30%), Positives = 206/489 (42%), Gaps = 74/489 (15%)
Query: 44 YHQPQAPANV---AKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCREL 100
YH N A + LRL S GRVEV + +WGT+CDD ++++ A VVCR+L
Sbjct: 138 YHGEDVGVNCYGEANLGLRLVDGNNSCS-GRVEVKFQERWGTICDDGWNLNTAAVVCRQL 196
Query: 101 GYVEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSD 160
G + + + PIWLD++ C GNE L C GWG DC H EDV + C D
Sbjct: 197 GCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYD 256
Query: 161 KRIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDK 220
D+ +R + T R G VE+K W +C
Sbjct: 257 S----------------------SDLELRLVGGTNR-----CMGRVELKIQGRWGTVCHH 289
Query: 221 HWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQ 280
W + VVC G + + S W + C+G E+ + C+
Sbjct: 290 KWNNAAADVVCKQLGCGTALHFAGLPHLQSGS---DVVWLDGVSCSGNESFLWDCRHSGT 346
Query: 281 VSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVE 340
V+ D C + V C G +RL G+ GRVE
Sbjct: 347 VNFD------CLHQNDVSVICSDGADLE-----------------LRLADGSNNCSGRVE 383
Query: 341 VLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIG---PIHLNEIQCTG 397
V + +W T+CD W A VVC++LG +V GSR + I +N I CTG
Sbjct: 384 VRIHEQWWTICDQNWKNEQALVVCKQLG---CPFSVFGSRRAKPSNEARDIWINSISCTG 440
Query: 398 NEKSIIDCKFNAES-QGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNG 456
NE ++ DC ++ ++ + C DAGV C+ A LRL G +P GR+EV +
Sbjct: 441 NESALWDCTYDGKAKRTCFRRSDAGVICSDKA---DLDLRLVGAHSPCYGRLEVKYQGE- 496
Query: 457 SLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTEL 516
WG VC W A VVC+QLG G + F T++ S + + V C G E
Sbjct: 497 ---WGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEA---SGPIWLDDVSCIGNES 550
Query: 517 SLAHCRHDG 525
++ C H G
Sbjct: 551 NIWDCEHSG 559
Score = 195 bits (495), Expect = 2e-49
Identities = 141/435 (32%), Positives = 192/435 (44%), Gaps = 49/435 (11%)
Query: 57 QLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGK 116
Q RL G S GRVEV + W +VCD DFS+HAA+V+CREL +A S + +GK
Sbjct: 794 QPRLVGADMPCS-GRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGK 852
Query: 117 GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQI 176
G G W + C G+E LA C C H+ +VGVVCS
Sbjct: 853 GNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCS----------------- 895
Query: 177 ENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF 236
+ D+R+ S +G VE+ W +CD HW +++RV+C
Sbjct: 896 -----RYTDVRLVNGKSQ-------CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSC 943
Query: 237 PGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKL----GPQVSLDPMKNVTCE 292
T + + R R W C G E+ + +C++ P +V C
Sbjct: 944 G---TALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICT 1000
Query: 293 NGLPAVVSCVPGQVFSP--DGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTV 350
L + V P E +RL G GRVE+ +G WGT+
Sbjct: 1001 GSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTI 1060
Query: 351 CDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAE 410
CDD WDL A VVC++LG G A A + G+G GPI L+++ CTG E + C
Sbjct: 1061 CDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGW 1120
Query: 411 SQ-GCNHEEDAGVRCNT-PAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNW 468
Q C H+EDAGV C+ A+ L + GR+EV NG+ WG V +N
Sbjct: 1121 GQHDCRHKEDAGVICSEFTALRLYSETETES----CAGRLEVFY--NGT--WGSVGRRNI 1172
Query: 469 GIVEAMVVCRQLGLG 483
A +VCRQLG G
Sbjct: 1173 TTAIAGIVCRQLGCG 1187
Score = 173 bits (438), Expect = 6e-43
Identities = 137/466 (29%), Positives = 198/466 (42%), Gaps = 69/466 (14%)
Query: 58 LRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKG 117
LRL G + S GR+EVY+ G+WGTVCDD ++ AA VVC +L + + G
Sbjct: 583 LRLVGGSNRCS-GRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTG 641
Query: 118 EGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIE 177
G IWLD++ C G+E+ L +C ++GWG DC H+EDVGV+CSD
Sbjct: 642 YGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSD----------------- 684
Query: 178 NLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFP 237
D+ +R + + R G VEV +C W + VVC
Sbjct: 685 -----ASDMELRLVGGSSR-----CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECG 734
Query: 238 GERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPA 297
+ + + + R + CTG EA + C K C + A
Sbjct: 735 SAIRVSREPH---FTERTLHILMSNSGCTGGEASLWDCIRW------EWKQTACHLNMEA 785
Query: 298 VVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDL 357
+ C A++ QP RL G GRVEV W +VCD + L
Sbjct: 786 SLIC---------------SAHR--QP--RLVGADMPCSGRVEVKHADTWRSVCDSDFSL 826
Query: 358 VSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQG-CNH 416
+A+V+CREL G A G G+G G + QC G+E + C + C H
Sbjct: 827 HAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIH 886
Query: 417 EEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVV 476
+ GV C+ +RL G++ +G+VE+ V + WG +C +W +A V+
Sbjct: 887 SREVGVVCSR-----YTDVRLVNGKSQCDGQVEINVLGH----WGSLCDTHWDPEDARVL 937
Query: 477 CRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCR 522
CRQL G A T + S +V C G E L +C+
Sbjct: 938 CRQLSCG---TALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQ 980
Score = 160 bits (405), Expect = 4e-39
Identities = 134/474 (28%), Positives = 196/474 (41%), Gaps = 77/474 (16%)
Query: 54 AKIQLRLAGQKRKHSE--GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTAS 111
A + LRL G HS GR+EV Y G+WGTVC D +S A VVC++LG +
Sbjct: 472 ADLDLRLVGA---HSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGM 528
Query: 112 SSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNS 171
+ + + GPIWLD++ C GNE+ + C +GWG +C H EDV V CS G
Sbjct: 529 TYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWG------ 582
Query: 172 LINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVC 231
+R + + R G +EV W +CD W +K + VVC
Sbjct: 583 ----------------LRLVGGSNR-----CSGRLEVYFQGRWGTVCDDGWNSKAAAVVC 621
Query: 232 GMFGFPGERTYNTKVYKM---FASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKN 288
P + + M AS + W + C G E+ + SC+ N
Sbjct: 622 SQLDCP------SSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCR------NSGWGN 669
Query: 289 VTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWG 348
C + V C +RL GG+ G+VEV G G
Sbjct: 670 NDCSHSEDVGVICSDASDME-----------------LRLVGGSSRCAGKVEVNVQGAVG 712
Query: 349 TVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDC-KF 407
+C + W + A VVCR+L GSA + I ++ CTG E S+ DC ++
Sbjct: 713 ILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRW 772
Query: 408 NAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQN 467
+ C+ +A + C+ ++ RL G P GRVEV + W VC +
Sbjct: 773 EWKQTACHLNMEASLICSA-----HRQPRLVGADMPCSGRVEV----KHADTWRSVCDSD 823
Query: 468 WGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHC 521
+ + A V+CR+L G A + + G + +C G+E LA C
Sbjct: 824 FSLHAANVLCRELNCGDAISLSVGDHFGKG---NGLTWAEKFQCEGSETHLALC 874
Score = 147 bits (372), Expect = 3e-35
Identities = 136/494 (27%), Positives = 197/494 (39%), Gaps = 67/494 (13%)
Query: 65 RKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLD 124
+ +G+VE+ G WG++CD + A V+CR+L A S T G+ +W
Sbjct: 906 KSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGH 965
Query: 125 NLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI-PGF----KFDNSLINQIENL 179
HC GNE+ L C G C H V V+C+ P F + ++ +
Sbjct: 966 RFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEG 1025
Query: 180 N--IQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFP 237
+ I +ED R+R + R G VE+ W ICD W ++ VVC G
Sbjct: 1026 SALICLEDKRLRLVDGDSR-----CAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG 1080
Query: 238 GERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPA 297
+N V F W ++CTG E+H+ C D C + A
Sbjct: 1081 V--AFNATVSAHFGEGSGP-IWLDDLNCTGMESHLWQCPSRGWGQHD------CRHKEDA 1131
Query: 298 VVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGE--GRVEVLKNGEWGTVCDDKW 355
V C E +RL GR+EV NG WG+V
Sbjct: 1132 GVIC-------------------SEFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNI 1172
Query: 356 DLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGC 414
A +VCR+LG G G G + +++IQC SI C E +
Sbjct: 1173 TTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRIS 1232
Query: 415 NHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAM 474
+ E+ + C + ++R+ GG GRVE+ GS WG VC +W + EA
Sbjct: 1233 SPAEETWITC-------EDRIRVRGGDTECSGRVEIW--HAGS--WGTVCDDSWDLAEAE 1281
Query: 475 VVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQG- 533
VVC+QLG G A A ++ + G + + + ++C G E L C A P G
Sbjct: 1282 VVCQQLGCGSALAALRDASFGQG---TGTIWLDDMRCKGNESFLWDCH------AKPWGQ 1332
Query: 534 ---GVQYGAGVACS 544
G + AGV CS
Sbjct: 1333 SDCGHKEDAGVRCS 1346
Score = 139 bits (349), Expect = 1e-32
Identities = 129/528 (24%), Positives = 203/528 (38%), Gaps = 106/528 (20%)
Query: 51 ANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTA 110
++ + ++LRL G + + G+VEV G G +C + + ++ A VVCR+L A +
Sbjct: 683 SDASDMELRLVGGSSRCA-GKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSR 741
Query: 111 SSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDN 170
+ + I + N CTG EA+L C W T C + ++CS R P
Sbjct: 742 EPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRL---- 797
Query: 171 SLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVV 230
+ A + G VEVK TW+ +CD ++ + V+
Sbjct: 798 -----------------VGADMPC--------SGRVEVKHADTWRSVCDSDFSLHAANVL 832
Query: 231 CGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVT 290
C + + + + W C G+E H++ C + T
Sbjct: 833 CRELNCGDAISLSVGDH---FGKGNGLTWAEKFQCEGSETHLALCPIVQH------PEDT 883
Query: 291 CENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTV 350
C + V C SR+ VRL G +G+VE+ G WG++
Sbjct: 884 CIHSREVGVVC-----------SRYTD--------VRLVNGKSQCDGQVEINVLGHWGSL 924
Query: 351 CDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA- 409
CD WD A V+CR+L G+A G +G+ + + C GNE + +C+
Sbjct: 925 CDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVL 984
Query: 410 ESQGCNHEEDAGVRC---------------NTPAMGL-----------QKKLRLNGGRNP 443
+ C H V C + P + K+LRL G +
Sbjct: 985 GAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR 1044
Query: 444 YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503
GRVE+ + WG +C W + +A VVC++LG G A NA + G S
Sbjct: 1045 CAGRVEIYHDG----FWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEG---SGP 1097
Query: 504 VVMSGVKCSGTELSLAHC------RHDGEDVACPQGGVQYGAGVACSE 545
+ + + C+G E L C +HD + AGV CSE
Sbjct: 1098 IWLDDLNCTGMESHLWQCPSRGWGQHDCRH--------KEDAGVICSE 1137
Score = 67.4 bits (163), Expect = 5e-11
Identities = 52/223 (23%), Positives = 81/223 (36%), Gaps = 35/223 (15%)
Query: 58 LRLAGQKRKHS-EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGK 116
LRL + S GR+EV+Y+G WG+V + + A +VCR+LG E + +
Sbjct: 1141 LRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKT 1200
Query: 117 GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQI 176
G G +W+D++ C ++ C S W E+ + C D+
Sbjct: 1201 GSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDR--------------- 1245
Query: 177 ENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF 236
IR+R G VE+ +W +CD W + VVC G
Sbjct: 1246 ---------IRVRG-------GDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGC 1289
Query: 237 PGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGP 279
+ + W M C G E+ + C P
Sbjct: 1290 GSAL---AALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKP 1329
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 173 bits (439), Expect = 5e-43
Identities = 115/390 (29%), Positives = 160/390 (41%), Gaps = 60/390 (15%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GR+EV++ G+WGTVCDD + + A V CRELG A + + +G G GP+W+D++ C
Sbjct: 209 GRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVGCG 268
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIR 189
G E L C + WG ++C H+ED G+VC+ R+R
Sbjct: 269 GGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAP-----------------------RLR 305
Query: 190 AILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVC-------------GMFGF 236
+ G +EV G W +CD W +++ V C G F
Sbjct: 306 LADGPHG-----CAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFG 360
Query: 237 PGERTYNTKVYKMFASRRKQRYWPF----SMDCTGTEAHISSCKLGPQVSLDPMKNVTCE 292
G + + R+ P DC E + C P + P
Sbjct: 361 EGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDSN 420
Query: 293 NGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLV-------------RLRGGAYIGEGRV 339
N P + P + P + P P V RL G GR+
Sbjct: 421 NSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGRL 480
Query: 340 EVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEA-VTGSRLGQGIGPIHLNEIQCTGN 398
EV + WGTVCDD WD+ ++VVCRELG G ++ R G G GPI L+++ C G
Sbjct: 481 EVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGT 540
Query: 399 EKSIIDCKFNA-ESQGCNHEEDAGVRCNTP 427
E S+ DC C H ED GV C P
Sbjct: 541 EASLSDCPAAPWGKHNCAHNEDVGVTCTGP 570
Score = 149 bits (376), Expect = 1e-35
Identities = 110/368 (29%), Positives = 160/368 (43%), Gaps = 65/368 (17%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G +EV G W +CD W +++ V C G G F W +
Sbjct: 31 GRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGA---FFGEGAGPVWLSEL 87
Query: 264 DCTGTEAHISSCK-------------------LGPQVSLDPMKNVTCENGLP-------- 296
C G E + C G +V+ + + +G P
Sbjct: 88 ACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDGAPWPGLLLEL 147
Query: 297 ------AVVSCVPGQVFSPDGPSRFRKAYKPEQ------PLV----------RLRGGAYI 334
+V+ P +P SR +K+ +P+Q PL+ RL G +
Sbjct: 148 SPSTEEPLVTHAPRPAGNPQNASR-KKSPRPKQAKSTRAPLLTTGAPRQERLRLVSGPHR 206
Query: 335 GEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQ 394
GR+EV G WGTVCDD WDL A+V CRELG G A A G+R G G GP+ ++++
Sbjct: 207 CAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVG 266
Query: 395 CTGNEKSIIDCKFNAESQ-GCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVE 453
C G E+++ DC + + C+H EDAG+ C PA +LRL G + GR+EV
Sbjct: 267 CGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPA----PRLRLADGPHGCAGRLEVW-- 320
Query: 454 RNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSG 513
G WG VC W + +A V CR+LG G A A ++ G S +++ ++C G
Sbjct: 321 HGGR--WGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEG---SGPIILDDLRCRG 375
Query: 514 TELSLAHC 521
E +L C
Sbjct: 376 NETALRFC 383
Score = 119 bits (298), Expect = 1e-26
Identities = 103/378 (27%), Positives = 146/378 (38%), Gaps = 99/378 (26%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVC------GMFGFPGERTYNTKVYKMFASRRKQR 257
G +EV G W +CD W +++ V C G PG + +
Sbjct: 209 GRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGPV-------- 260
Query: 258 YWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRK 317
W + C G E + C P C++ A + C GP+
Sbjct: 261 -WMDDVGCGGGEQALRDC------PRSPWGRSNCDHSEDAGLVCT--------GPA---- 301
Query: 318 AYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVT 377
P +RL G + GR+EV G WG+VCDD WDL A+V CRELG G A A
Sbjct: 302 ------PRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPG 355
Query: 378 GSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQ-GCNHEEDAGVRCNTPAMG------ 430
G+ G+G GPI L++++C GNE ++ C Q C+H EDAG C+ +G
Sbjct: 356 GAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTA 415
Query: 431 -------------------LQKKLRLNGGRNPYEGRVEVLVER----------------- 454
+ + G +P VL E
Sbjct: 416 PTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSK 475
Query: 455 -NGSL-VW-----GMVCGQNWGIVEAMVVCRQLGLGFASN----AFQETWYWHGDVNSNK 503
+G L VW G VC +W + ++ VVCR+LG G A + W +
Sbjct: 476 CSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGW------GAGP 529
Query: 504 VVMSGVKCSGTELSLAHC 521
+ + V C GTE SL+ C
Sbjct: 530 IWLDDVGCVGTEASLSDC 547
Score = 107 bits (266), Expect = 5e-23
Identities = 56/161 (34%), Positives = 88/161 (54%), Gaps = 15/161 (9%)
Query: 13 LAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQ--PQAPANVAK------------IQL 58
+AML P + + P+ +P+ E + P++P + A ++
Sbjct: 713 MAMLTTQGPQEMTSESTIKSIPQASLEPSAEIPEGSPESPKDPAPSPSVSTTGESGLFRV 772
Query: 59 RLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGE 118
RLA + + GR+EV++ G+WGTVCDD++ + A V C ELG + + + YG G
Sbjct: 773 RLADGPNRCA-GRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831
Query: 119 GPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCS 159
GPIWLD++ C G+EA+L+ C S WG +C H EDVG+ C+
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCT 872
Score = 103 bits (258), Expect = 5e-22
Identities = 56/130 (43%), Positives = 74/130 (56%), Gaps = 11/130 (8%)
Query: 31 PHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSI 90
P P +P PE PQ LRL K S GR+EV++D +WGTVCDD + +
Sbjct: 449 PASPTVLWEPGPEAGSPQ---------LRLVAGPSKCS-GRLEVWHDQRWGTVCDDSWDM 498
Query: 91 HAAHVVCRELGYVEAKSWT-ASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCK 149
+ VVCRELG + A+ +G G GPIWLD++ C G EA+L+ C + WG +C
Sbjct: 499 RDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCA 558
Query: 150 HTEDVGVVCS 159
H EDVGV C+
Sbjct: 559 HNEDVGVTCT 568
Score = 102 bits (255), Expect = 1e-21
Identities = 44/102 (43%), Positives = 62/102 (60%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GR+EV++ G+WGTVCDD + + A V CR+LG A + + +G+G GP+WL L C
Sbjct: 31 GRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGAGPVWLSELACR 90
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNS 171
GNE L C GW C H ED GVVC+ +R+ + D++
Sbjct: 91 GNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDST 132
Score = 97.1 bits (240), Expect = 6e-20
Identities = 48/100 (48%), Positives = 62/100 (62%), Gaps = 1/100 (1%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
+RL G + GR+EV G WGTVCDD WDL A+V CR+LG G A A G+ G+G
Sbjct: 20 LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79
Query: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRC 424
GP+ L+E+ C GNE + C ++ C+HEEDAGV C
Sbjct: 80 GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVC 119
Score = 97.1 bits (240), Expect = 6e-20
Identities = 59/153 (38%), Positives = 75/153 (49%), Gaps = 10/153 (6%)
Query: 273 SSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGA 332
S+ K PQ SL+P + E + P S G S + VRL G
Sbjct: 728 STIKSIPQASLEPSAEIP-EGSPESPKDPAPSPSVSTTGESGLFR--------VRLADGP 778
Query: 333 YIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNE 392
GR+EV G WGTVCDD WDL A+V C ELG G + V + G G GPI L++
Sbjct: 779 NRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGTGPIWLDD 838
Query: 393 IQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRC 424
+ C G+E S+ DC A C+HEED G+ C
Sbjct: 839 MGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTC 871
Score = 51.2 bits (121), Expect = 4e-06
Identities = 36/99 (36%), Positives = 50/99 (50%), Gaps = 9/99 (9%)
Query: 429 MGLQ--KKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFAS 486
+G+Q ++LRL G + GR+EV +G WG VC W + +A V CRQLG G A
Sbjct: 12 VGIQAVERLRLADGPHGCAGRLEVW---HGGR-WGTVCDDGWDLRDAAVACRQLGCGGAL 67
Query: 487 NAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525
A ++ G + V +S + C G E L C H G
Sbjct: 68 AAPGGAFFGEG---AGPVWLSELACRGNEGQLGLCHHRG 103
Score = 48.1 bits (113), Expect = 3e-05
Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 434 KLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETW 493
++RL G N GR+EV WG VC NW + +A V C +LG G +T
Sbjct: 771 RVRLADGPNRCAGRLEVWHAGR----WGTVCDDNWDLRDATVACWELGCGKVRPRVGKTH 826
Query: 494 YWHGDVNSNKVVMSGVKCSGTELSLAHC 521
Y G + + + + C G+E SL+ C
Sbjct: 827 YGPG---TGPIWLDDMGCKGSEASLSDC 851
Score = 38.1 bits (87), Expect = 0.031
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 3/75 (4%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G +EV W +CD +W +++ V C G R +V K W M
Sbjct: 783 GRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVR---PRVGKTHYGPGTGPIWLDDM 839
Query: 264 DCTGTEAHISSCKLG 278
C G+EA +S C G
Sbjct: 840 GCKGSEASLSDCPSG 854
>gi|5174411 CD5 molecule-like [Homo sapiens]
Length = 347
Score = 161 bits (408), Expect = 2e-39
Identities = 121/375 (32%), Positives = 161/375 (42%), Gaps = 59/375 (15%)
Query: 58 LRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSY--- 114
+RL G + EGRVEV GQWGTVCDD + I V+CRELG A + Y
Sbjct: 24 VRLVGGLHR-CEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPP 82
Query: 115 GKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLIN 174
+ E + + ++ CTG E TLA C V DC H ED G C N
Sbjct: 83 AEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCE--------------N 126
Query: 175 QIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMF 234
+ + E +R+ +G VEVK W +C W+ + ++VVC
Sbjct: 127 PESSFSPVPEGVRLA-------DGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQL 179
Query: 235 GFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENG 294
G G K A RK W M C+G EA + C GP KN TC +
Sbjct: 180 GC-GRAVLTQKRCNKHAYGRKP-IWLSQMSCSGREATLQDCPSGPWG-----KN-TCNHD 231
Query: 295 LPAVVSCVPGQVFSPDGPSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVCDD 353
V C E P +RL GG + GR+EVL G WG+VCDD
Sbjct: 232 EDTWVEC--------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDD 271
Query: 354 KWDLVSASVVCRELGFGSAKEAVTGSR--LGQGIGPIHLNEIQCTGNEKSIIDCKFNAES 411
W VVC++LG G + R G G+G I L+ ++C+G E+S+ C+
Sbjct: 272 NWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWG 331
Query: 412 -QGCNHEEDAGVRCN 425
C H+ED V C+
Sbjct: 332 FHDCTHQEDVAVICS 346
Score = 155 bits (393), Expect = 1e-37
Identities = 114/328 (34%), Positives = 157/328 (47%), Gaps = 41/328 (12%)
Query: 203 EGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFS 262
EG VEV++ W +CD W K+ V+C G + + + ++Q+ S
Sbjct: 34 EGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQS 93
Query: 263 MDCTGTEAHISSCKLGP--QVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYK 320
+ CTGTE ++ C+ S D +CEN P FSP
Sbjct: 94 VSCTGTEDTLAQCEQEEVYDCSHDEDAGASCEN---------PESSFSP----------V 134
Query: 321 PEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSR 380
PE VRL G +GRVEV +W TVC W L +A VVCR+LG G A +T R
Sbjct: 135 PEG--VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRA--VLTQKR 190
Query: 381 LGQ---GIGPIHLNEIQCTGNEKSIIDCKFNAESQG-CNHEEDAGVRCNTPAMGLQKKLR 436
+ G PI L+++ C+G E ++ DC + CNH+ED V C P LR
Sbjct: 191 CNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPF-----DLR 245
Query: 437 LNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFA-SNAFQETWYW 495
L GG N GR+EVL + VWG VC NWG E VVC+QLG G + S +F++ +
Sbjct: 246 LVGGDNLCSGRLEVLHKG----VWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCY 301
Query: 496 HGDVNSNKVVMSGVKCSGTELSLAHCRH 523
V ++ + V+CSG E SL C+H
Sbjct: 302 GPGV--GRIWLDNVRCSGEEQSLEQCQH 327
Score = 121 bits (304), Expect = 2e-27
Identities = 80/225 (35%), Positives = 109/225 (48%), Gaps = 27/225 (12%)
Query: 303 PGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASV 362
PG + SP G VRL GG + EGRVEV + G+WGTVCDD WD+ +V
Sbjct: 15 PGFLASPSG--------------VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAV 60
Query: 363 VCRELGFGSAKEAVTG---SRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEED 419
+CRELG G+A +G + + + + CTG E ++ C+ E C+H+ED
Sbjct: 61 LCRELGCGAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCE-QEEVYDCSHDED 119
Query: 420 AGVRCNTPAMG---LQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVV 476
AG C P + + +RL G +GRVEV + W VC W + A VV
Sbjct: 120 AGASCENPESSFSPVPEGVRLADGPGHCKGRVEVKHQNQ----WYTVCQTGWSLRAAKVV 175
Query: 477 CRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHC 521
CRQLG G A Q+ H + +S + CSG E +L C
Sbjct: 176 CRQLGCGRAV-LTQKRCNKHA-YGRKPIWLSQMSCSGREATLQDC 218
Score = 64.7 bits (156), Expect = 3e-10
Identities = 37/90 (41%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
Query: 435 LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWY 494
+RL GG + EGRVEV E+ G WG VC W I + V+CR+LG G AS Y
Sbjct: 24 VRLVGGLHRCEGRVEV--EQKGQ--WGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79
Query: 495 WHGDVNSNKVVMSGVKCSGTELSLAHCRHD 524
KV++ V C+GTE +LA C +
Sbjct: 80 EPPAEKEQKVLIQSVSCTGTEDTLAQCEQE 109
>gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]
Length = 343
Score = 156 bits (394), Expect = 8e-38
Identities = 113/310 (36%), Positives = 154/310 (49%), Gaps = 38/310 (12%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
+RL G +GRVEVL G WGTVCDD WD A+VVCR+LG G A A +R GQG
Sbjct: 18 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 77
Query: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN--TPAMGLQKK-------- 434
GPI L++++C+GNE + C N S C H EDAGV C+ P ++ +
Sbjct: 78 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLC 137
Query: 435 ----------LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGF 484
LRL G + +GRVEVL + WG VC +W +A VVCRQLG G+
Sbjct: 138 SPIGPESSLALRLVNGGDRCQGRVEVLYRGS----WGTVCDDSWDTNDANVVCRQLGCGW 193
Query: 485 ASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544
A++A + G S +V+ V+CSG E L C ++G G AGV CS
Sbjct: 194 ATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPNNG--WLSHNCGHHEDAGVICS 248
Query: 545 ETAPDLVLNAEMVQQTTYL--EDRPMFMLQCAMEENCLSASAAQT---DPTT-GYRRLLR 598
+ V Q+ L P+F + CA ++ + AA T PTT ++L
Sbjct: 249 GSW--AVAGPRRPQEMPGLARAQDPLFWMMCAAQDTSPTCGAAPTMAGSPTTVAIMKMLV 306
Query: 599 FSSQIHNNGQ 608
S+Q + G+
Sbjct: 307 SSAQFPSPGR 316
Score = 128 bits (321), Expect = 2e-29
Identities = 97/278 (34%), Positives = 129/278 (46%), Gaps = 37/278 (13%)
Query: 203 EGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFA---SRRKQRYW 259
+G VEV +W +CD W ++ VVC G + M A +R Q
Sbjct: 28 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG---------WAMLAPGNARFGQGSG 78
Query: 260 PFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSP----DGP 312
P +D C+G E+++ SC +S + C + A V C G +P P
Sbjct: 79 PIVLDDVRCSGNESYLWSCPHNGWLSHN------CGHSEDAGVICSGGPPRTPIRPRSWP 132
Query: 313 SRFR-KAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFG 370
SRF PE L +RL G +GRVEVL G WGTVCDD WD A+VVCR+LG G
Sbjct: 133 SRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG 192
Query: 371 SAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCNTPAM 429
A A +R GQG GPI L++++C+G+E + C N S C H EDAGV C+
Sbjct: 193 WATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS---- 248
Query: 430 GLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQN 467
+ G R P E + L L W M Q+
Sbjct: 249 ---GSWAVAGPRRPQE--MPGLARAQDPLFWMMCAAQD 281
Score = 114 bits (286), Expect = 3e-25
Identities = 76/224 (33%), Positives = 110/224 (49%), Gaps = 41/224 (18%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
+GRVEV Y G WGTVCDD + + A+VVCR+LG A ++ +G+G GPI LD++ C
Sbjct: 28 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRC 87
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCS--DKRIP------GFKFDNSLINQIENLN 180
+GNE+ L +C NGW +C H+ED GV+CS R P +F S I +L
Sbjct: 88 SGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLCSPIGPESSLA 147
Query: 181 IQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG----- 235
+++ + R +G VEV +W +CD W ++ VVC G
Sbjct: 148 LRLVNGGDRC------------QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 195
Query: 236 -FPGERTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSC 275
PG +R Q P +D C+G E+++ SC
Sbjct: 196 SAPGN------------ARFGQGSGPIVLDDVRCSGHESYLWSC 227
Score = 103 bits (258), Expect = 5e-22
Identities = 50/113 (44%), Positives = 72/113 (63%), Gaps = 3/113 (2%)
Query: 47 PQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAK 106
P P + ++L G + +GRVEV Y G WGTVCDD + + A+VVCR+LG A
Sbjct: 139 PIGPESSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 195
Query: 107 SWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCS 159
S ++ +G+G GPI LD++ C+G+E+ L +C +NGW +C H ED GV+CS
Sbjct: 196 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248
>gi|194018748 CD6 molecule [Homo sapiens]
Length = 668
Score = 130 bits (328), Expect = 4e-30
Identities = 102/321 (31%), Positives = 143/321 (44%), Gaps = 39/321 (12%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G VEV+ +W+ C W ++ + VC G G + A + P +
Sbjct: 56 GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGG-----AEAASQLAPPTPELPPPPAA 110
Query: 264 DCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQ 323
T A+ + P + + CE V DG R + E
Sbjct: 111 GNTSVAANATLAG-APALLCSGAEWRLCE---------VVEHACRSDG--RRARVTCAEN 158
Query: 324 PLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQ 383
+RL G GRVE+L++GEWG+VCDD WDL A VVCR+LG G A +A+ G
Sbjct: 159 RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218
Query: 384 GIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNP 443
G GPIH +++ C+G E + DC C H+EDAG C+ + RL GG +
Sbjct: 219 GRGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGHKEDAGAVCSE-----HQSWRLTGGADR 273
Query: 444 YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503
EG+VEV VW VC W EA V+C+ LG G A + G +S
Sbjct: 274 CEGQVEVHFRG----VWNTVCDSEWYPSEAKVLCQSLGCGTAVERPK------GLPHS-- 321
Query: 504 VVMSG---VKCSGTELSLAHC 521
+SG C+G EL+L++C
Sbjct: 322 --LSGRMYYSCNGEELTLSNC 340
Score = 84.0 bits (206), Expect = 5e-16
Identities = 63/209 (30%), Positives = 81/209 (38%), Gaps = 43/209 (20%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129
GRVE+ G+WG+VCDD + + AHVVCR+LG A + G GPI D ++C+
Sbjct: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231
Query: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDK---RIPGFKFDNSLINQIENLNIQVEDI 186
G EA L C G C H ED G VCS+ R+ G
Sbjct: 232 GAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTG--------------------- 269
Query: 187 RIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKV 246
EG VEV W +CD W ++V+C G G K
Sbjct: 270 -----------GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC-GTAVERPKG 317
Query: 247 YKMFASRRKQRYWPFSMDCTGTEAHISSC 275
S R C G E +S+C
Sbjct: 318 LPHSLSGR------MYYSCNGEELTLSNC 340
Score = 71.6 bits (174), Expect = 3e-12
Identities = 73/233 (31%), Positives = 87/233 (37%), Gaps = 29/233 (12%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
VRL G+ G VEV W C WD +A VCR LG G A+ A S+L
Sbjct: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA---SQLAPPT 101
Query: 386 GPIHLNEIQCTGNEKSIIDCKF---------NAESQGCNHEEDA----GVRCNTPAMGLQ 432
L GN + AE + C E A G R
Sbjct: 102 P--ELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARV-TCAEN 158
Query: 433 KKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQET 492
+ LRL G GRVE+L WG VC W + +A VVCRQLG G+A A
Sbjct: 159 RALRLVDGGGACAGRVEMLEHGE----WGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGL 214
Query: 493 WYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSE 545
+ G + V CSG E L C C G + AG CSE
Sbjct: 215 HFTPG---RGPIHRDQVNCSGAEAYLWDCPGLPGQHYC---GHKEDAGAVCSE 261
Score = 71.6 bits (174), Expect = 3e-12
Identities = 97/368 (26%), Positives = 135/368 (36%), Gaps = 74/368 (20%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGY--VEAKSWTASSSYGKGEGPIWLDNLH 127
G VEV + W C + AA VCR LG EA S A + P N
Sbjct: 56 GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPA-AGNTS 114
Query: 128 CTGNEATLAACTSNGWGVTDCKHTEDVGVVC-SDKRIPGFKFDNSLINQIENLNIQVEDI 186
N ATLA + + + E V C SD R + + EN +++ D
Sbjct: 115 VAAN-ATLAGAPALLCSGAEWRLCEVVEHACRSDGR-------RARVTCAENRALRLVD- 165
Query: 187 RIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG-------FPGE 239
G VE+ E W +CD W +++ VVC G PG
Sbjct: 166 -----------GGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPG- 213
Query: 240 RTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299
+ + + ++C+G EA++ C GLP
Sbjct: 214 ---------LHFTPGRGPIHRDQVNCSGAEAYLWDCP-----------------GLPGQH 247
Query: 300 SCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVS 359
C G A E RL GGA EG+VEV G W TVCD +W
Sbjct: 248 YC---------GHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSE 298
Query: 360 ASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDC--KFNAESQGCNHE 417
A V+C+ LG G+A E G G ++ + C G E ++ +C +FN S C+
Sbjct: 299 AKVLCQSLGCGTAVERPKGLPHSLS-GRMYYS---CNGEELTLSNCSWRFN-NSNLCSQS 353
Query: 418 EDAGVRCN 425
A V C+
Sbjct: 354 LAARVLCS 361
Score = 45.1 bits (105), Expect = 3e-04
Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 10/97 (10%)
Query: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELG---YVEAKSWTASSSYGKGEGPIWLDN 125
EG+VEV++ G W TVCD ++ A V+C+ LG VE S G+
Sbjct: 275 EGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGR-------MY 327
Query: 126 LHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKR 162
C G E TL+ C+ C + V+CS R
Sbjct: 328 YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364
Score = 36.6 bits (83), Expect = 0.091
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 430 GLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAF 489
G + +RL G + G VEV +E + W CG W A VCR LG G A A
Sbjct: 40 GERLPVRLTNGSSSCSGTVEVRLEAS----WEPACGALWDSRAAEAVCRALGCGGAEAAS 95
Query: 490 Q 490
Q
Sbjct: 96 Q 96
>gi|5031863 galectin 3 binding protein [Homo sapiens]
Length = 585
Score = 112 bits (280), Expect = 1e-24
Identities = 53/100 (53%), Positives = 65/100 (65%), Gaps = 1/100 (1%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
+RL G +GRVE+ G+WGTVCD+ WDL ASVVCR LGF +A +A+ + GQG
Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83
Query: 386 GPIHLNEIQCTGNEKSIIDCK-FNAESQGCNHEEDAGVRC 424
GPI L+E+QCTG E S+ DCK C HE DAGV C
Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVC 123
Score = 107 bits (268), Expect = 3e-23
Identities = 46/94 (48%), Positives = 66/94 (70%)
Query: 68 SEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLH 127
++GRVE++Y GQWGTVCD+ + + A VVCR LG+ A +++G+G GPI LD +
Sbjct: 33 NQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQ 92
Query: 128 CTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDK 161
CTG EA+LA C S GW ++C+H D GVVC+++
Sbjct: 93 CTGTEASLADCKSLGWLKSNCRHERDAGVVCTNE 126
Score = 58.2 bits (139), Expect = 3e-08
Identities = 33/91 (36%), Positives = 46/91 (50%), Gaps = 7/91 (7%)
Query: 435 LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWY 494
+RL G +GRVE+ WG VC W + +A VVCR LG A+ A +
Sbjct: 24 MRLADGGATNQGRVEIFYRGQ----WGTVCDNLWDLTDASVVCRALGFENATQALGRAAF 79
Query: 495 WHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525
G S +++ V+C+GTE SLA C+ G
Sbjct: 80 GQG---SGPIMLDEVQCTGTEASLADCKSLG 107
Score = 38.5 bits (88), Expect = 0.024
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 9/77 (11%)
Query: 203 EGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFS 262
+G VE+ W +CD W ++ VVC GF + + Q P
Sbjct: 34 QGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGF------ENATQALGRAAFGQGSGPIM 87
Query: 263 MD---CTGTEAHISSCK 276
+D CTGTEA ++ CK
Sbjct: 88 LDEVQCTGTEASLADCK 104
>gi|5803080 macrophage receptor with collagenous structure [Homo
sapiens]
Length = 520
Score = 107 bits (266), Expect = 5e-23
Identities = 50/104 (48%), Positives = 62/104 (59%), Gaps = 6/104 (5%)
Query: 56 IQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYG 115
+ +R+ G + GR EVYY G WGT+CDD++ A V CR LGY + + A G
Sbjct: 422 VSVRIVGSSNR---GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGR---ALYKVG 475
Query: 116 KGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCS 159
G G IWLDN+ C G E+TL +CT N WG DC H ED GV CS
Sbjct: 476 AGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519
Score = 81.3 bits (199), Expect = 3e-15
Identities = 41/101 (40%), Positives = 57/101 (56%), Gaps = 6/101 (5%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
VR+ G + GR EV +G WGT+CDD+W A V CR LG+ + ++G G
Sbjct: 424 VRIVGSS--NRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALY---KVGAGT 478
Query: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN 425
G I L+ +QC G E ++ C N+ C+HEEDAGV C+
Sbjct: 479 GQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519
Score = 41.2 bits (95), Expect = 0.004
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 6/72 (8%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G EV TW ICD W ++ V C M G+ R +YK+ A + W ++
Sbjct: 433 GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRA----LYKVGAG--TGQIWLDNV 486
Query: 264 DCTGTEAHISSC 275
C GTE+ + SC
Sbjct: 487 QCRGTESTLWSC 498
Score = 38.5 bits (88), Expect = 0.024
Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 12/87 (13%)
Query: 435 LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWY 494
+R+ G N GR EV S WG +C W +A+V CR LG ++
Sbjct: 424 VRIVGSSN--RGRAEVYY----SGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKV--- 474
Query: 495 WHGDVNSNKVVMSGVKCSGTELSLAHC 521
+ ++ + V+C GTE +L C
Sbjct: 475 ---GAGTGQIWLDNVQCRGTESTLWSC 498
>gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo
sapiens]
Length = 451
Score = 106 bits (265), Expect = 7e-23
Identities = 49/100 (49%), Positives = 65/100 (65%), Gaps = 1/100 (1%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
VRL GG+ EGRVE+L +G+WGT+CDD+W++ VVCR LG+ + + GQG
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409
Query: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRC 424
GPI LNE+ C G E SI +CK ++ C+H EDAGV C
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 449
Score = 105 bits (263), Expect = 1e-22
Identities = 44/103 (42%), Positives = 64/103 (62%), Gaps = 1/103 (0%)
Query: 57 QLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGK 116
++RL G H EGRVE+ + GQWGT+CDD + + VVCR LGY ++ ++ +G+
Sbjct: 349 KVRLVGGSGPH-EGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQ 407
Query: 117 GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCS 159
G GPIWL+ + C G E+++ C WG C H+ED GV C+
Sbjct: 408 GTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450
Score = 53.1 bits (126), Expect = 9e-07
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
Query: 434 KLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETW 493
K+RL GG P+EGRVE+L S WG +C W + VVCR LG +
Sbjct: 349 KVRLVGGSGPHEGRVEIL----HSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAH 404
Query: 494 YWHGDVNSNKVVMSGVKCSGTELSLAHCR 522
+ G + + ++ V C G E S+ C+
Sbjct: 405 FGQG---TGPIWLNEVFCFGRESSIEECK 430
Score = 44.7 bits (104), Expect = 3e-04
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 3/75 (4%)
Query: 203 EGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFS 262
EG VE+ W ICD W + +VVC G+PG + + + + W
Sbjct: 360 EGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAH---FGQGTGPIWLNE 416
Query: 263 MDCTGTEAHISSCKL 277
+ C G E+ I CK+
Sbjct: 417 VFCFGRESSIEECKI 431
>gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]
Length = 495
Score = 101 bits (251), Expect = 3e-21
Identities = 46/106 (43%), Positives = 65/106 (61%), Gaps = 1/106 (0%)
Query: 54 AKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSS 113
A + +RL H EGRVEVY+D +WGTVCDD + VVCR LG+ + ++
Sbjct: 389 APMMIRLVNGSGPH-EGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTAR 447
Query: 114 YGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCS 159
+G+G G IW+D++ C G E T+ C+ + WGVT+C H ED V C+
Sbjct: 448 FGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493
Score = 95.5 bits (236), Expect = 2e-19
Identities = 46/102 (45%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Query: 325 LVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQG 384
++RL G+ EGRVEV + WGTVCDD WD VVCR LGF +E +R GQG
Sbjct: 392 MIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQG 451
Query: 385 IGPIHLNEIQCTGNEKSIIDCKFNAES-QGCNHEEDAGVRCN 425
G I ++++ C G E++I C F+ C H EDA V CN
Sbjct: 452 TGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493
Score = 55.8 bits (133), Expect = 1e-07
Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 7/87 (8%)
Query: 435 LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWY 494
+RL G P+EGRVEV +R WG VC W + VVCR LG ++ +
Sbjct: 393 IRLVNGSGPHEGRVEVYHDRR----WGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARF 448
Query: 495 WHGDVNSNKVVMSGVKCSGTELSLAHC 521
G + ++ M V C GTE ++ C
Sbjct: 449 GQG---TGRIWMDDVACKGTEETIFRC 472
Score = 49.7 bits (117), Expect = 1e-05
Identities = 28/74 (37%), Positives = 34/74 (45%), Gaps = 5/74 (6%)
Query: 203 EGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPG-ERTYNTKVYKMFASRRKQRYWPF 261
EG VEV + W +CD W K+ VVC M GF G E Y T + + R W
Sbjct: 403 EGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARF----GQGTGRIWMD 458
Query: 262 SMDCTGTEAHISSC 275
+ C GTE I C
Sbjct: 459 DVACKGTEETIFRC 472
>gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]
Length = 782
Score = 98.2 bits (243), Expect = 3e-20
Identities = 46/97 (47%), Positives = 64/97 (65%), Gaps = 2/97 (2%)
Query: 331 GAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIG-PIH 389
G G GRVEV G WGTVCDD W++ A+VVCR+LGF A AV + GQG PI
Sbjct: 680 GLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPIL 739
Query: 390 LNEIQCTGNEKSIIDCKFN-AESQGCNHEEDAGVRCN 425
L++++C G E+++++C+ N + C H+EDAGV C+
Sbjct: 740 LDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776
Score = 94.7 bits (234), Expect = 3e-19
Identities = 45/91 (49%), Positives = 58/91 (63%), Gaps = 1/91 (1%)
Query: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEG-PIWLDNLHC 128
GRVEV+ G+WGTVCDD ++I A VVCR+LG+ A + +G+G PI LD++ C
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745
Query: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCS 159
G E L C NG G +C+H ED GVVCS
Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776
Score = 68.2 bits (165), Expect = 3e-11
Identities = 42/111 (37%), Positives = 55/111 (49%), Gaps = 8/111 (7%)
Query: 440 GRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDV 499
G + GRVEV V WG VC +W I A VVCRQLG +A A + + G
Sbjct: 680 GLSSGSGRVEVFVGGR----WGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQG-- 733
Query: 500 NSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPDL 550
S +++ V+C+G E +L C+H+G V AGV CS PDL
Sbjct: 734 GSLPILLDDVRCAGWERNLLECQHNG--VGTHNCEHDEDAGVVCSHQNPDL 782
Score = 34.7 bits (78), Expect = 0.35
Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 8/76 (10%)
Query: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263
G VEV G W +CD W + VVC GF Y + K A + P +
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGF----AYAVRAVKR-AEFGQGGSLPILL 740
Query: 264 D---CTGTEAHISSCK 276
D C G E ++ C+
Sbjct: 741 DDVRCAGWERNLLECQ 756
>gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo
sapiens]
Length = 388
Score = 50.8 bits (120), Expect = 5e-06
Identities = 18/41 (43%), Positives = 25/41 (60%)
Query: 119 GPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCS 159
GPIWL+ + C G E+++ C WG C H+ED GV C+
Sbjct: 347 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387
Score = 46.2 bits (108), Expect = 1e-04
Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 370 GSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRC 424
G E +G+ L G PI LNE+ C G E SI +CK ++ C+H EDAGV C
Sbjct: 333 GQKGEKGSGNTLSTG--PIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 386
>gi|119392081 complement factor I preproprotein [Homo sapiens]
Length = 583
Score = 42.7 bits (99), Expect = 0.001
Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 437 LNGGRNPYEGRVEV-LVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYW 495
L G EG VEV LV+++ ++ +C +W + EA V C L LGF A + +
Sbjct: 116 LKHGNTDSEGIVEVKLVDQDKTM---FICKSSWSMREANVAC--LDLGFQQGADTQRRFK 170
Query: 496 HGDVNSNKVVMSGVKCSGTELSLAHC 521
D++ N V C G E SLA C
Sbjct: 171 LSDLSINSTECLHVHCRGLETSLAEC 196
Score = 39.3 bits (90), Expect = 0.014
Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 4/104 (3%)
Query: 326 VRLRGGAYIGEGRVEVLKNGEWGT--VCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQ 383
V L+ G EG VEV + T +C W + A+V C +LGF + +L
Sbjct: 114 VSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSD 173
Query: 384 -GIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDAGVRCNT 426
I + C G E S+ +C F + + +++ A V C T
Sbjct: 174 LSINSTECLHVHCRGLETSLAECTF-TKRRTMGYQDFADVVCYT 216
Score = 31.6 bits (70), Expect = 2.9
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 68 SEGRVEVYYDGQWGT--VCDDDFSIHAAHVVCRELGYVE-AKSWTASSSYGKGEGPIWLD 124
SEG VEV Q T +C +S+ A+V C +LG+ + A +
Sbjct: 123 SEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECL 182
Query: 125 NLHCTGNEATLAACT 139
++HC G E +LA CT
Sbjct: 183 HVHCRGLETSLAECT 197
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 35.4 bits (80), Expect = 0.20
Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 72 VEVYYDGQWGTVCDDDFSIHAAHVVCRELG---YVEAKSWTASSSYGK 116
++V+ W T+C DD+ H A+V C +LG YV + + SS G+
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSSDNLRVSSLEGQ 164
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/79 (26%), Positives = 32/79 (40%), Gaps = 14/79 (17%)
Query: 307 FSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGR--------------VEVLKNGEWGTVCD 352
F G R R ++K + + R G + +G ++V W T+C
Sbjct: 71 FDCSGKYRCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAVLQVFTAASWKTMCS 130
Query: 353 DKWDLVSASVVCRELGFGS 371
D W A+V C +LGF S
Sbjct: 131 DDWKGHYANVACAQLGFPS 149
Score = 30.0 bits (66), Expect = 8.5
Identities = 10/32 (31%), Positives = 15/32 (46%)
Query: 206 VEVKEGKTWKQICDKHWTAKNSRVVCGMFGFP 237
++V +WK +C W + V C GFP
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLGFP 148
>gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo
sapiens]
Length = 344
Score = 35.4 bits (80), Expect = 0.20
Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 72 VEVYYDGQWGTVCDDDFSIHAAHVVCRELG---YVEAKSWTASSSYGK 116
++V+ W T+C DD+ H A+V C +LG YV + + SS G+
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSSDNLRVSSLEGQ 164
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/79 (26%), Positives = 32/79 (40%), Gaps = 14/79 (17%)
Query: 307 FSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGR--------------VEVLKNGEWGTVCD 352
F G R R ++K + + R G + +G ++V W T+C
Sbjct: 71 FDCSGKYRCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAVLQVFTAASWKTMCS 130
Query: 353 DKWDLVSASVVCRELGFGS 371
D W A+V C +LGF S
Sbjct: 131 DDWKGHYANVACAQLGFPS 149
Score = 30.0 bits (66), Expect = 8.5
Identities = 10/32 (31%), Positives = 15/32 (46%)
Query: 206 VEVKEGKTWKQICDKHWTAKNSRVVCGMFGFP 237
++V +WK +C W + V C GFP
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLGFP 148
>gi|166197668 CD5 molecule [Homo sapiens]
Length = 495
Score = 33.9 bits (76), Expect = 0.59
Identities = 23/53 (43%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
Query: 323 QPLV--RLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSA--SVVCRELGFGS 371
QP V RL GG+ I EG VEV + +W +CD S VCRE GS
Sbjct: 271 QPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGS 323
Score = 32.0 bits (71), Expect = 2.2
Identities = 28/118 (23%), Positives = 45/118 (38%), Gaps = 27/118 (22%)
Query: 436 RLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWG--------IVEAMVVCRQLGLGFASN 487
RL + +G++EV ++ W MVC Q+WG +A VC++L G +
Sbjct: 36 RLTRSNSKCQGQLEVYLKDG----WHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91
Query: 488 AFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSE 545
G S + C G S ++C H D+ + G+ C E
Sbjct: 92 L--------GPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMC-------HSLGLTCLE 134
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 33.1 bits (74), Expect = 1.0
Identities = 25/87 (28%), Positives = 33/87 (37%), Gaps = 11/87 (12%)
Query: 291 CENG--LPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWG 348
C+NG +P V C G + DG E VR G G V W
Sbjct: 650 CKNGECVPLVNLC-DGHLHCEDGSD--------EADCVRFFNGTTNNNGLVRFRIQSIWH 700
Query: 349 TVCDDKWDLVSASVVCRELGFGSAKEA 375
T C + W ++ VC+ LG GS +
Sbjct: 701 TACAENWTTQISNDVCQLLGLGSGNSS 727
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,206,042
Number of Sequences: 37866
Number of extensions: 1590541
Number of successful extensions: 3781
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2925
Number of HSP's gapped (non-prelim): 254
length of query: 774
length of database: 18,247,518
effective HSP length: 110
effective length of query: 664
effective length of database: 14,082,258
effective search space: 9350619312
effective search space used: 9350619312
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.