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Search of human proteins with 4504415
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504415 major histocompatibility complex, class I, G
precursor [Homo sapiens]
(338 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504415 major histocompatibility complex, class I, G precurso... 701 0.0
gi|24797067 major histocompatibility complex, class I, A precurs... 594 e-170
gi|17986001 major histocompatibility complex, class I, B precurs... 572 e-163
gi|52630342 major histocompatibility complex, class I, C precurs... 559 e-159
gi|149158702 major histocompatibility complex, class I, F isofor... 553 e-158
gi|149158698 major histocompatibility complex, class I, F isofor... 553 e-158
gi|62912479 major histocompatibility complex, class I, E precurs... 549 e-156
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 474 e-134
gi|149158700 major histocompatibility complex, class I, F isofor... 311 5e-85
gi|4504417 major histocompatibility complex, class I-related [Ho... 226 2e-59
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 203 2e-52
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 191 8e-49
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 191 1e-48
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 186 3e-47
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 159 3e-39
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 142 6e-34
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 134 2e-31
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 131 1e-30
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 130 2e-30
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 130 2e-30
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 102 5e-22
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 102 5e-22
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 94 2e-19
gi|110618224 CD1A antigen precursor [Homo sapiens] 87 2e-17
gi|110618227 CD1C antigen precursor [Homo sapiens] 69 5e-12
gi|239740920 PREDICTED: similar to major histocompatibility comp... 69 6e-12
gi|239740918 PREDICTED: similar to major histocompatibility comp... 69 6e-12
gi|169168591 PREDICTED: similar to major histocompatibility comp... 67 2e-11
gi|24797076 major histocompatibility complex, class II, DP beta ... 66 5e-11
gi|4502645 CD1B antigen precursor [Homo sapiens] 65 1e-10
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 701 bits (1810), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 1 MVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRF 60
MVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRF
Sbjct: 1 MVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRF 60
Query: 61 DSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQ 120
DSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQ
Sbjct: 61 DSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQ 120
Query: 121 WMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQR 180
WMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQR
Sbjct: 121 WMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQR 180
Query: 181 RAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILT 240
RAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILT
Sbjct: 181 RAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILT 240
Query: 241 WQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQ 300
WQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQ
Sbjct: 241 WQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQ 300
Query: 301 SSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD 338
SSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
Sbjct: 301 SSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD 338
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 594 bits (1532), Expect = e-170
Identities = 280/338 (82%), Positives = 307/338 (90%)
Query: 1 MVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRF 60
M VMAPRTL LLLSGAL LT+TWAGSHSMRYF +VSRPGRGEPRFIA+GYVDDTQFVRF
Sbjct: 1 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF 60
Query: 61 DSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQ 120
DSD+A RMEPRAPW+EQEGPEYW++ETRN KA +QTDR++L TLRGYYNQSEA SHT+Q
Sbjct: 61 DSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQ 120
Query: 121 WMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQR 180
M GCD+GSDGR LRGY Q AYDGKDY+ALNEDLRSWTAAD AAQI+KRK EAA+ AEQ
Sbjct: 121 IMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQL 180
Query: 181 RAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILT 240
RAYL+GTCVEWL RYLENGKE LQR DPPKTH+THHP+ D+EATLRCWALGFYPAEI LT
Sbjct: 181 RAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLT 240
Query: 241 WQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQ 300
WQRDGEDQTQD ELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLP+PL LRW+
Sbjct: 241 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL 300
Query: 301 SSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD 338
SS PTIPI+GI+AGLV+L AV+TGA VAAV+WR+KSSD
Sbjct: 301 SSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSD 338
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 572 bits (1475), Expect = e-163
Identities = 273/337 (81%), Positives = 300/337 (89%)
Query: 1 MVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRF 60
M+VMAPRT+ LLLS AL LTETWAGSHSMRYF +VSRPGRGEPRFI++GYVDDTQFVRF
Sbjct: 1 MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRF 60
Query: 61 DSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQ 120
DSD+A PR EPRAPW+EQEGPEYW+ T+ KA AQTDR +L+ LRGYYNQSEA SHTLQ
Sbjct: 61 DSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQ 120
Query: 121 WMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQR 180
M GCD+G DGRLLRG++QYAYDGKDY+ALNEDLRSWTAADTAAQI++RK EAA AEQR
Sbjct: 121 SMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR 180
Query: 181 RAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILT 240
RAYLEG CVEWL RYLENGK+ L+RADPPKTHVTHHP+ D+EATLRCWALGFYPAEI LT
Sbjct: 181 RAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLT 240
Query: 241 WQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQ 300
WQRDGEDQTQD ELVETRPAGD TFQKWAAVVVPSGEEQRYTCHVQHEGLP+PL LRW+
Sbjct: 241 WQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 300
Query: 301 SSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
SS T+PI+GIVAGL VLA VV GA VAAV+ R+KSS
Sbjct: 301 SSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSS 337
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 559 bits (1441), Expect = e-159
Identities = 271/338 (80%), Positives = 293/338 (86%), Gaps = 1/338 (0%)
Query: 1 MVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRF 60
M VMAPR L LLLSG L LTETWA SHSMRYF AVSRPGRGEPRFI++GYVDDTQFVRF
Sbjct: 1 MRVMAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRF 60
Query: 61 DSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQ 120
DSD+A PR EPRAPWVEQEGPEYW+ ET+ K AQ DR++L+ LRGYYNQSE SHTLQ
Sbjct: 61 DSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQ 120
Query: 121 WMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQR 180
M GCDLG DGRLLRGY+Q AYDGKDY+ALNEDLRSWTAADTAAQI++RK EAA AEQ
Sbjct: 121 RMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQL 180
Query: 181 RAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILT 240
RAYLEGTCVEWL RYLENGKE LQRA+PPKTHVTHHP+ D+EATLRCWALGFYPAEI LT
Sbjct: 181 RAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLT 240
Query: 241 WQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQ 300
WQRDGEDQTQD ELVETRPAGDGTFQKWAAVVVPSG+EQRYTCH+QHEGL EPL L W+
Sbjct: 241 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEP 300
Query: 301 SSLPTIPIMGIVAGLVVLAAV-VTGAAVAAVLWRKKSS 337
SS PTIPIMGIVAGL VL + V GA V A++ R+KSS
Sbjct: 301 SSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSS 338
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 553 bits (1426), Expect = e-158
Identities = 265/335 (79%), Positives = 292/335 (87%)
Query: 4 MAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSD 63
MAPR+L LLLSGAL LT+TWAGSHS+RYFS AVSRPGRGEPR+IA+ YVDDTQF+RFDSD
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 64 SACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMI 123
+A PRMEPR PWVEQEGP+YWE T KA+AQTDR+ L+ L YNQSEA SHTLQ M
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 124 GCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQRRAY 183
GCD+G DGRLLRGY Q+AYDGKDY++LNEDLRSWTAADT AQI++R EA AE+ R Y
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
LEG C+E L RYLENGKE LQRADPPK HV HHP+ D+EATLRCWALGFYPAEI LTWQR
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 244 DGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSL 303
DGE+QTQD ELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+PL+LRW+QS
Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
Query: 304 PTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD 338
PTIPI+GIVAGLVVL AVVTGA VAAV+WRKKSSD
Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSD 335
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 553 bits (1426), Expect = e-158
Identities = 265/335 (79%), Positives = 292/335 (87%)
Query: 4 MAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSD 63
MAPR+L LLLSGAL LT+TWAGSHS+RYFS AVSRPGRGEPR+IA+ YVDDTQF+RFDSD
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 64 SACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMI 123
+A PRMEPR PWVEQEGP+YWE T KA+AQTDR+ L+ L YNQSEA SHTLQ M
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 124 GCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQRRAY 183
GCD+G DGRLLRGY Q+AYDGKDY++LNEDLRSWTAADT AQI++R EA AE+ R Y
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
LEG C+E L RYLENGKE LQRADPPK HV HHP+ D+EATLRCWALGFYPAEI LTWQR
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 244 DGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSL 303
DGE+QTQD ELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+PL+LRW+QS
Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
Query: 304 PTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD 338
PTIPI+GIVAGLVVL AVVTGA VAAV+WRKKSSD
Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSD 335
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 549 bits (1415), Expect = e-156
Identities = 257/334 (76%), Positives = 290/334 (86%)
Query: 4 MAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSD 63
M TL LLLS AL LT+TWAGSHS++YF +VSRPGRGEPRFI++GYVDDTQFVRFD+D
Sbjct: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
Query: 64 SACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMI 123
+A PRM PRAPW+EQEG EYW+ ETR+ + AQ R+NL+TLRGYYNQSEA SHTLQWM
Sbjct: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
Query: 124 GCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQRRAY 183
GC+LG DGR LRGYEQ+AYDGKDYL LNEDLRSWTA DTAAQIS++K A+ AE +RAY
Sbjct: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
Query: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
LE TCVEWLH+YLE GKE L +PPKTHVTHHP+ D+EATLRCWALGFYPAEI LTWQ+
Sbjct: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
Query: 244 DGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSL 303
DGE TQD ELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEP+ LRWK +S
Sbjct: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
Query: 304 PTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
PTIPI+GI+AGLV+L +VV+GA VAAV+WRKKSS
Sbjct: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSS 334
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 474 bits (1219), Expect = e-134
Identities = 230/313 (73%), Positives = 257/313 (82%), Gaps = 4/313 (1%)
Query: 25 GSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSACPRMEPRAPWVEQEGPEYW 84
GSHS+RYF AVSRPG GEPRFI++GYVDDTQFVRFDSDSA PR EPRAPW+EQEGPEYW
Sbjct: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
Query: 85 EEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGCDLGSDGRLLRGYEQYAYDG 144
+E+TR K AQ+ R+ L TLRGYYNQSEA SHTLQ M GCD+G DGR LRG+ Q AYDG
Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
Query: 145 KDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQRRAYLEGTCVEWLHRYLENGKEMLQ 204
+DY+ALNEDLRSWTAADTAAQI+KRK EAA AE++R YLEG CVE L RYLE GK+ L
Sbjct: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217
Query: 205 RADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQTQDVELVETRPAGDGT 264
RADPPK HVTHHP+ + E TLRCWALGFYP EI LTWQR+GEDQTQD+ELVETRP+GDGT
Sbjct: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277
Query: 265 FQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTG 324
FQKWAA+VVPSGEEQRYTC VQHEGL EPL LRW+ + IMGI+ GLV+L V
Sbjct: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFL-IMGIIVGLVLL---VVA 333
Query: 325 AAVAAVLWRKKSS 337
AV+WRKK S
Sbjct: 334 LVAGAVIWRKKRS 346
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 311 bits (797), Expect = 5e-85
Identities = 151/204 (74%), Positives = 171/204 (83%)
Query: 4 MAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSD 63
MAPR+L LLLSGAL LT+TWAGSHS+RYFS AVSRPGRGEPR+IA+ YVDDTQF+RFDSD
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 64 SACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMI 123
+A PRMEPR PWVEQEGP+YWE T KA+AQTDR+ L+ L YNQSEA SHTLQ M
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 124 GCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQRRAY 183
GCD+G DGRLLRGY Q+AYDGKDY++LNEDLRSWTAADT AQI++R EA AE+ R Y
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 184 LEGTCVEWLHRYLENGKEMLQRAD 207
LEG C+E L RYLENGKE LQRA+
Sbjct: 181 LEGECLELLRRYLENGKETLQRAE 204
Score = 67.0 bits (162), Expect = 2e-11
Identities = 34/42 (80%), Positives = 37/42 (88%)
Query: 297 RWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD 338
R +QS PTIPI+GIVAGLVVL AVVTGA VAAV+WRKKSSD
Sbjct: 202 RAEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSD 243
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 226 bits (577), Expect = 2e-59
Identities = 124/313 (39%), Positives = 182/313 (58%), Gaps = 13/313 (4%)
Query: 26 SHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSACPRMEPRAPWV-EQEGPEYW 84
+HS+RYF VS P G P FI++GYVD +DS + + EPRAPW+ E P++W
Sbjct: 24 THSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTR--QKEPRAPWMAENLAPDHW 81
Query: 85 EEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGCDLGSDGRLLRGYEQYAYDG 144
E T+ + Q ++ L+ L+ +YN S SHT Q MIGC+L DG G+ QYAYDG
Sbjct: 82 ERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCELLEDGSTT-GFLQYAYDG 138
Query: 145 KDYLALNEDLRSWTAADTAAQISKRKCEAANVAE--QRRAYLEGTCVEWLHRYLENGKEM 202
+D+L N+D SW A D A K+ EA N E ++ +LE C+ WL R+LE GK+
Sbjct: 139 QDFLIFNKDTLSWLAVDNVAHTIKQAWEA-NQHELLYQKNWLEEECIAWLKRFLEYGKDT 197
Query: 203 LQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQTQDVELVETRPAGD 262
LQR +PP V F L C A GFYP EI +TW ++GE+ Q+++ + P+GD
Sbjct: 198 LQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGD 257
Query: 263 GTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVV 322
GT+Q WA++ + Y+CHV+H G+ L + + ++P +M V+G +VL V+
Sbjct: 258 GTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPL--VMKAVSGSIVLVIVL 315
Query: 323 TGAAVAAVLWRKK 335
G V ++WR++
Sbjct: 316 AG--VGVLVWRRR 326
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 203 bits (517), Expect = 2e-52
Identities = 120/335 (35%), Positives = 179/335 (53%), Gaps = 9/335 (2%)
Query: 6 PRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSA 65
P L L+L L SHS+ Y S G F A+GYVDD FV +D +S
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 66 CPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIG 124
R+EPR PWV + W + +++ K ++ T+ +N S+ SHTLQ ++G
Sbjct: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK-ESHTLQVILG 123
Query: 125 CDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANV-AEQRRAY 183
C++ D GY +Y YDG+D+L D W AA+ A +K + E + A Q RAY
Sbjct: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
Query: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
LE C L + LE G+ +L + PP VTHH V TLRC AL +YP I + W +
Sbjct: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLK 241
Query: 244 DGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSS 302
D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +PL++ W+ S
Sbjct: 242 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 301
Query: 303 LPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
T+ ++G+++G+ V ++ + +L +++ S
Sbjct: 302 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 335
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 191 bits (485), Expect = 8e-49
Identities = 108/296 (36%), Positives = 166/296 (56%), Gaps = 9/296 (3%)
Query: 45 RFIAMGYVDDTQFVRFDSDSACPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQ 103
R + +GYVDD FV +D +S R+EPR PWV + W + +++ K ++
Sbjct: 23 RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
Query: 104 TLRGYYNQSEASSHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTA 163
T+ +N S+ SHTLQ ++GC++ D GY +Y YDG+D+L D W AA+
Sbjct: 81 TIMENHNHSK-ESHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
Query: 164 AQISKRKCEAANV-AEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYE 222
A +K + E + A Q RAYLE C L + LE G+ +L + PP VTHH V
Sbjct: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
Query: 223 ATLRCWALGFYPAEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRY 281
TLRC AL +YP I + W +D + ++ E + P GDGT+Q W + VP GEEQRY
Sbjct: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
Query: 282 TCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
TC V+H GL +PL++ W+ S T+ ++G+++G+ V ++ + +L +++ S
Sbjct: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 312
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 191 bits (484), Expect = 1e-48
Identities = 112/303 (36%), Positives = 162/303 (53%), Gaps = 7/303 (2%)
Query: 1 MVVMAPRTL-FLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVR 59
MV M P L LLL G E G +S+ Y +S+ P F A+G ++D QF R
Sbjct: 1 MVRMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFR 60
Query: 60 FDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTL 119
++S + +P W + EG E W+++++ KA L+ + YYN S S H L
Sbjct: 61 YNSKDR--KSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGS-HVL 117
Query: 120 QWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQ 179
Q GC++ + R + +Y YDGKDY+ N+++ +W D AAQI+K+K EA V Q
Sbjct: 118 QGRFGCEI-ENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQ 176
Query: 180 R-RAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEII 238
R +AYLE C L +YL+ K +L R DPP VT H + L+C A FYP +I
Sbjct: 177 RAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKID 236
Query: 239 LTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRW 298
+ W R GE Q ++ + G+GT+Q W V VP + Y+CHVQH L +PL++ W
Sbjct: 237 VHWTRAGEVQEPELR-GDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPW 295
Query: 299 KQS 301
+ S
Sbjct: 296 EAS 298
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 186 bits (471), Expect = 3e-47
Identities = 115/335 (34%), Positives = 174/335 (51%), Gaps = 23/335 (6%)
Query: 6 PRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSA 65
P L L+L L SHS+ Y S G F A+GYVDD FV +D +S
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 66 CPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIG 124
R+EPR PWV + W + +++ K ++ T+ +N S+ SHTLQ ++G
Sbjct: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK-ESHTLQVILG 123
Query: 125 CDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANV-AEQRRAY 183
C++ D GY +Y YDG+D+L D W AA+ A +K + E + A Q RAY
Sbjct: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
Query: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
LE C L + LE G+ +L + VT TLRC AL +YP I + W +
Sbjct: 183 LERDCPAQLQQLLELGRGVLDQ------QVT---------TLRCRALNYYPQNITMKWLK 227
Query: 244 DGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSS 302
D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +PL++ W+ S
Sbjct: 228 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 287
Query: 303 LPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
T+ ++G+++G+ V ++ + +L +++ S
Sbjct: 288 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 321
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 159 bits (403), Expect = 3e-39
Identities = 86/224 (38%), Positives = 129/224 (57%), Gaps = 5/224 (2%)
Query: 116 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN 175
SHTLQ ++GC++ D GY +Y YDG+D+L D W AA+ A +K + E
Sbjct: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 176 V-AEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYP 234
+ A Q RAYLE C L + LE G+ +L + PP VTHH V TLRC AL +YP
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
Query: 235 AEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEP 293
I + W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
Query: 294 LMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
L++ W+ S T+ ++G+++G+ V ++ + +L +++ S
Sbjct: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 247
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 142 bits (357), Expect = 6e-34
Identities = 81/224 (36%), Positives = 124/224 (55%), Gaps = 19/224 (8%)
Query: 116 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN 175
SHTLQ ++GC++ D GY +Y YDG+D+L D W AA+ A +K + E
Sbjct: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 176 V-AEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYP 234
+ A Q RAYLE C L + LE G+ +L + VT TLRC AL +YP
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQ------QVT---------TLRCRALNYYP 130
Query: 235 AEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEP 293
I + W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
Query: 294 LMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
L++ W+ S T+ ++G+++G+ V ++ + +L +++ S
Sbjct: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 233
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 134 bits (336), Expect = 2e-31
Identities = 87/291 (29%), Positives = 143/291 (49%), Gaps = 18/291 (6%)
Query: 9 LFLLLSGALTLTETWAGS--HSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSAC 66
+FLLL+G A + HS+RY +S G + F+ ++D F+R D
Sbjct: 6 VFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKC- 64
Query: 67 PRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGC 125
R +P+ W E G + W+ ETR+ + + RM L ++ + H+LQ + C
Sbjct: 65 -RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK----DQKEGLHSLQEIRVC 119
Query: 126 DLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWT------AADTAAQISKRKCEAANVAEQ 179
++ D R + + YDG+ +L+ N + + WT A A + E A +
Sbjct: 120 EIHEDNST-RSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKT 178
Query: 180 RRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIIL 239
+ C++ L RYL++G +L+R PP +VT + T+ C A GFYP I L
Sbjct: 179 HYHAMHADCLQELRRYLKSGV-VLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITL 237
Query: 240 TWQRDGEDQTQDVELV-ETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEG 289
+W++DG + D + + P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 238 SWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSG 288
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 131 bits (329), Expect = 1e-30
Identities = 87/293 (29%), Positives = 143/293 (48%), Gaps = 24/293 (8%)
Query: 9 LFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSACPR 68
LFL ++ A HS+RY +S+ G + F+A G++D F+R+D R
Sbjct: 8 LFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR--R 65
Query: 69 MEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGCDL 127
+P+ W E G + W+ ET + + Q R L ++ + H+LQ + C++
Sbjct: 66 AKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIK----DQKGGLHSLQEIRVCEI 121
Query: 128 GSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVA---------- 177
D RG + YDG+ +L+ N + T T Q S+ + A NV
Sbjct: 122 HEDSST-RGSRHFYYDGELFLSQNLE----TQESTVPQSSRAQTLAMNVTNFWKEDAMKT 176
Query: 178 EQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEI 237
+ ++ C++ L RYL++G ++R PP +VT V + T+ C A FYP I
Sbjct: 177 KTHYRAMQADCLQKLQRYLKSGVA-IRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNI 235
Query: 238 ILTWQRDGEDQTQDVELV-ETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEG 289
LTW++DG + + + + P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 236 TLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 130 bits (327), Expect = 2e-30
Identities = 100/334 (29%), Positives = 160/334 (47%), Gaps = 26/334 (7%)
Query: 9 LFLLLSGALTLTETWAGSH-SMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSACP 67
L LL G+L A SH S+ Y AVS P G P F G++ Q++ ++S
Sbjct: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG-- 66
Query: 68 RMEPRAPWV-EQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGCD 126
EP WV E + YWE+ET + + + + L G +TLQ ++GC+
Sbjct: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCE 120
Query: 127 LGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADT---AAQISKRKCEAANVAEQRRAY 183
LG D + ++A +G++++ N DL+ T A IS+R + A + +
Sbjct: 121 LGPDNTSVPT-AKFALNGEEFM--NFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF 177
Query: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
L +C L +LE G+ L+ +PP + P + L C A FYP E+ L + R
Sbjct: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237
Query: 244 DGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSL 303
+G + P DG+F +++ V SG+E Y C VQH GL +PL + + +
Sbjct: 238 NG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAK 295
Query: 304 PTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
++ ++GIV G+++L A G A+LWR+ S
Sbjct: 296 SSVLVVGIVIGVLLLTAAAVG---GALLWRRMRS 326
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 130 bits (327), Expect = 2e-30
Identities = 100/334 (29%), Positives = 160/334 (47%), Gaps = 26/334 (7%)
Query: 9 LFLLLSGALTLTETWAGSH-SMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSACP 67
L LL G+L A SH S+ Y AVS P G P F G++ Q++ ++S
Sbjct: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG-- 66
Query: 68 RMEPRAPWV-EQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGCD 126
EP WV E + YWE+ET + + + + L G +TLQ ++GC+
Sbjct: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCE 120
Query: 127 LGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADT---AAQISKRKCEAANVAEQRRAY 183
LG D + ++A +G++++ N DL+ T A IS+R + A + +
Sbjct: 121 LGPDNTSVPT-AKFALNGEEFM--NFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF 177
Query: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
L +C L +LE G+ L+ +PP + P + L C A FYP E+ L + R
Sbjct: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237
Query: 244 DGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSL 303
+G + P DG+F +++ V SG+E Y C VQH GL +PL + + +
Sbjct: 238 NG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAK 295
Query: 304 PTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
++ ++GIV G+++L A G A+LWR+ S
Sbjct: 296 SSVLVVGIVIGVLLLTAAAVG---GALLWRRMRS 326
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 102 bits (254), Expect = 5e-22
Identities = 50/131 (38%), Positives = 78/131 (59%), Gaps = 3/131 (2%)
Query: 208 PPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQ 266
PP VTHH V TLRC AL +YP I + W +D + ++ E + P GDGT+Q
Sbjct: 27 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
Query: 267 KWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAA 326
W + VP GEEQRYTC V+H GL +PL++ W+ S T+ ++G+++G+ V ++
Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 144
Query: 327 VAAVLWRKKSS 337
+ +L +++ S
Sbjct: 145 LFIILRKRQGS 155
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 102 bits (254), Expect = 5e-22
Identities = 50/131 (38%), Positives = 78/131 (59%), Gaps = 3/131 (2%)
Query: 208 PPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQ 266
PP VTHH V TLRC AL +YP I + W +D + ++ E + P GDGT+Q
Sbjct: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
Query: 267 KWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAA 326
W + VP GEEQRYTC V+H GL +PL++ W+ S T+ ++G+++G+ V ++
Sbjct: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232
Query: 327 VAAVLWRKKSS 337
+ +L +++ S
Sbjct: 233 LFIILRKRQGS 243
Score = 53.1 bits (126), Expect = 3e-07
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 3/109 (2%)
Query: 6 PRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSA 65
P L L+L L SHS+ Y S G F A+GYVDD FV +D +S
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 66 CPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSE 113
R+EPR PWV + W + +++ K ++ T+ +N S+
Sbjct: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 94.0 bits (232), Expect = 2e-19
Identities = 43/115 (37%), Positives = 71/115 (61%), Gaps = 2/115 (1%)
Query: 224 TLRCWALGFYPAEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYT 282
TLRC AL +YP I + W +D + ++ E + P GDGT+Q W + VP GEEQRYT
Sbjct: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
Query: 283 CHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
C V+H GL +PL++ W+ S T+ ++G+++G+ V ++ + +L +++ S
Sbjct: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 229
Score = 53.9 bits (128), Expect = 2e-07
Identities = 34/112 (30%), Positives = 52/112 (46%), Gaps = 3/112 (2%)
Query: 6 PRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSA 65
P L L+L L SHS+ Y S G F A+GYVDD FV +D +S
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
Query: 66 CPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASS 116
R+EPR PWV + W + +++ K ++ T+ +N S+ ++
Sbjct: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTT 116
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 87.0 bits (214), Expect = 2e-17
Identities = 77/297 (25%), Positives = 133/297 (44%), Gaps = 25/297 (8%)
Query: 47 IAMGYVDDTQFVRFDSDSACPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTL 105
+ G++ D Q +DS+S+ + PW E W+E T +T R + + +
Sbjct: 44 LVSGWLSDLQTHTWDSNSST--IVFLCPWSRGNFSNEEWKE--LETLFRIRTIR-SFEGI 98
Query: 106 RGYYNQSEAS-SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAA 164
R Y ++ + +Q GC+L S G++ + Q AY G D+++ + SW A
Sbjct: 99 RRYAHELQFEYPFEIQVTGGCELHS-GKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAG 155
Query: 165 QISKRKCEAANVAEQRRAY----LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPV-F 219
++K C+ N + L TC ++ L+ GK LQR P+ ++H P
Sbjct: 156 NMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPG 215
Query: 220 DYEATLRCWALGFYPAEIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQ 279
L C GFYP + + W R GE + Q + + P+ DGT+ A + V +GE
Sbjct: 216 PGHLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAA 274
Query: 280 RYTCHVQHEGLP-EPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKK 335
+C V+H L + ++L W+ S I+ ++ L++L + LW +K
Sbjct: 275 DLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLL--------IGLALWFRK 323
>gi|110618227 CD1C antigen precursor [Homo sapiens]
Length = 333
Score = 69.3 bits (168), Expect = 5e-12
Identities = 58/224 (25%), Positives = 97/224 (43%), Gaps = 19/224 (8%)
Query: 119 LQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN--- 175
+Q GC+L S G+ G+ Q A++G D L+ +W + +++ C N
Sbjct: 114 VQVKAGCELHS-GKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQY 170
Query: 176 --VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDY-EATLRCWALGF 232
V E + TC +L L+ GK + R P+ ++ P + L C A GF
Sbjct: 171 EGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGF 230
Query: 233 YPAEIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL-P 291
YP + +TW R+ ++Q + + P DGT+ + V S E +C V+H L
Sbjct: 231 YPKPVWVTWMRNEQEQL-GTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGG 289
Query: 292 EPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKK 335
+ ++L W + ++ LV+L + VLW KK
Sbjct: 290 QDIILYWGHHFSMNWIALVVIVPLVIL--------IVLVLWFKK 325
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 68.9 bits (167), Expect = 6e-12
Identities = 51/193 (26%), Positives = 82/193 (42%), Gaps = 11/193 (5%)
Query: 134 LRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN-VAEQRRAYLEGTCVEWL 192
+RG +Y Y+ ++Y + D+ + A + + V E+ RA L+ C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVC---R 112
Query: 193 HRYLENGKEMLQRADPPKTHVT--HHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQTQ 250
H Y + LQR P ++ ++ L C FYPA+I + W R+ +++T
Sbjct: 113 HNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETT 172
Query: 251 DVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIM- 309
V GD TFQ + + YTCHV+H L P+++ W+ S M
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKML 232
Query: 310 ----GIVAGLVVL 318
G V GL+ L
Sbjct: 233 SGIGGFVLGLIFL 245
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 68.9 bits (167), Expect = 6e-12
Identities = 51/193 (26%), Positives = 82/193 (42%), Gaps = 11/193 (5%)
Query: 134 LRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN-VAEQRRAYLEGTCVEWL 192
+RG +Y Y+ ++Y + D+ + A + + V E+ RA L+ C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVC---R 112
Query: 193 HRYLENGKEMLQRADPPKTHVT--HHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQTQ 250
H Y + LQR P ++ ++ L C FYPA+I + W R+ +++T
Sbjct: 113 HNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETT 172
Query: 251 DVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIM- 309
V GD TFQ + + YTCHV+H L P+++ W+ S M
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKML 232
Query: 310 ----GIVAGLVVL 318
G V GL+ L
Sbjct: 233 SGIGGFVLGLIFL 245
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 67.0 bits (162), Expect = 2e-11
Identities = 50/193 (25%), Positives = 81/193 (41%), Gaps = 11/193 (5%)
Query: 134 LRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN-VAEQRRAYLEGTCVEWL 192
+RG +Y Y+ ++Y + D+ + A + + V E+ RA ++ C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVC---R 112
Query: 193 HRYLENGKEMLQRADPPKTHVT--HHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQTQ 250
H Y + LQR P ++ ++ L C FYPA+I + W R+ +++T
Sbjct: 113 HNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETA 172
Query: 251 DVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIM- 309
V GD TFQ + + YTCHV+H L P+ + W+ S M
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKML 232
Query: 310 ----GIVAGLVVL 318
G V GL+ L
Sbjct: 233 SGIGGFVLGLIFL 245
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 65.9 bits (159), Expect = 5e-11
Identities = 48/196 (24%), Positives = 82/196 (41%), Gaps = 6/196 (3%)
Query: 135 RGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAA-NVAEQRRAYLEGTCVEWLH 193
R E+Y Y+ +++ + D+ + A + + + ++ E++RA + C H
Sbjct: 52 RFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMC---RH 108
Query: 194 RYLENGKEMLQRADPPKTHVTHHPV--FDYEATLRCWALGFYPAEIILTWQRDGEDQTQD 251
Y G LQR P+ +V+ + L C FYP I + W +G+++T
Sbjct: 109 NYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAG 168
Query: 252 VELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIMGI 311
V GD TFQ + + + YTC V+H L P+ + WK S
Sbjct: 169 VVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLT 228
Query: 312 VAGLVVLAAVVTGAAV 327
AG VL ++ G +
Sbjct: 229 GAGGFVLGLIICGVGI 244
>gi|4502645 CD1B antigen precursor [Homo sapiens]
Length = 333
Score = 64.7 bits (156), Expect = 1e-10
Identities = 69/283 (24%), Positives = 122/283 (43%), Gaps = 28/283 (9%)
Query: 50 GYVDDTQFVRFDSDSACPR-MEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGY 108
G++DD Q +DSDS ++P W + + K A+ + + + G+
Sbjct: 48 GWLDDLQIHGWDSDSGTAIFLKP------------WSKGNFSDKEVAELEEIFRVYIFGF 95
Query: 109 YNQSEASS--------HTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNED--LRSWT 158
+ + + +Q + GC+L S G ++ + + A G D+L++ + S
Sbjct: 96 AREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIV-SFLRGALGGLDFLSVKNASCVPSPE 154
Query: 159 AADTAAQISKRKCEAANVAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPV 218
A + + + E R L TC +L L GK LQR P+ ++ P
Sbjct: 155 GGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPS 214
Query: 219 -FDYEATLRCWALGFYPAEIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGE 277
L C GFYP + + W R GE + Q +L + P + T+ A + V GE
Sbjct: 215 PGPGRLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQLGDILPNANWTWYLRATLDVADGE 273
Query: 278 EQRYTCHVQHEGLP-EPLMLRWKQ-SSLPTIPIMGIVAGLVVL 318
+C V+H L + ++L W+ +S+ +I + IV L++L
Sbjct: 274 AAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLL 316
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,028,579
Number of Sequences: 37866
Number of extensions: 656808
Number of successful extensions: 1784
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1594
Number of HSP's gapped (non-prelim): 149
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.