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Search of human proteins with 4502337
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
(298 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 624 e-179
gi|17986001 major histocompatibility complex, class I, B precurs... 207 9e-54
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 198 5e-51
gi|24797067 major histocompatibility complex, class I, A precurs... 197 7e-51
gi|149158702 major histocompatibility complex, class I, F isofor... 191 5e-49
gi|149158698 major histocompatibility complex, class I, F isofor... 191 5e-49
gi|4504415 major histocompatibility complex, class I, G precurso... 191 9e-49
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 185 5e-47
gi|52630342 major histocompatibility complex, class I, C precurs... 183 1e-46
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 183 1e-46
gi|4504417 major histocompatibility complex, class I-related [Ho... 182 4e-46
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 178 4e-45
gi|62912479 major histocompatibility complex, class I, E precurs... 178 4e-45
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 157 1e-38
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 142 4e-34
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 122 3e-28
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 122 3e-28
gi|149158700 major histocompatibility complex, class I, F isofor... 113 2e-25
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 104 8e-23
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 98 1e-20
gi|110618224 CD1A antigen precursor [Homo sapiens] 88 1e-17
gi|150418002 major histocompatibility complex, class II, DQ beta... 86 5e-17
gi|239740920 PREDICTED: similar to major histocompatibility comp... 82 6e-16
gi|239740918 PREDICTED: similar to major histocompatibility comp... 82 6e-16
gi|169168591 PREDICTED: similar to major histocompatibility comp... 82 7e-16
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 79 5e-15
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 79 6e-15
gi|4502649 CD1D antigen precursor [Homo sapiens] 78 8e-15
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 73 3e-13
gi|110618227 CD1C antigen precursor [Homo sapiens] 73 3e-13
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 624 bits (1608), Expect = e-179
Identities = 298/298 (100%), Positives = 298/298 (100%)
Query: 1 MVRMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFR 60
MVRMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFR
Sbjct: 1 MVRMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFR 60
Query: 61 YNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGR 120
YNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGR
Sbjct: 61 YNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGR 120
Query: 121 FGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKA 180
FGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKA
Sbjct: 121 FGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKA 180
Query: 181 YLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWT 240
YLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWT
Sbjct: 181 YLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWT 240
Query: 241 RAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298
RAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS
Sbjct: 241 RAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 207 bits (527), Expect = 9e-54
Identities = 116/294 (39%), Positives = 166/294 (56%), Gaps = 8/294 (2%)
Query: 11 LLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSK--DRKS 68
LLLL E G +S+ Y YT +S+ P F ++G ++D QF R++S +
Sbjct: 10 LLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRE 69
Query: 69 QPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVLQGRFGCEI-E 126
+P W + EG E W +++Q+ KA+ E+L+++ YYN S GSH LQ +GC++
Sbjct: 70 EPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGP 129
Query: 127 NNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEEC 186
+ R +Y YDGKDYI N+++ +W D AAQIT++KWEA QR +AYLE EC
Sbjct: 130 DGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR-RAYLEGEC 188
Query: 187 PATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGE-- 244
LR+YL+ K+ L+R DPP VT H + L+C A FYP +I + W R GE
Sbjct: 189 VEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ 248
Query: 245 VQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298
Q+ EL + G+ T+Q W V VP + Y+CHVQH L +PL + WE S
Sbjct: 249 TQDTEL-VETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPS 301
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 198 bits (503), Expect = 5e-51
Identities = 113/302 (37%), Positives = 167/302 (55%), Gaps = 11/302 (3%)
Query: 3 RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62
R P LL LL+LL AV Q +SL Y++ G S+ + F+ALG ++D F Y+
Sbjct: 4 RARPALL-LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYD 62
Query: 63 SKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRF 121
+ R+ +P W + W Q SQ K + +F I+E +N S SH LQ
Sbjct: 63 HESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVIL 122
Query: 122 GCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAY 181
GCE++ + S+ +WKY YDG+D++EF + W +P A TK +WE + ++ +AY
Sbjct: 123 GCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
Query: 182 LEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTR 241
LE +CPA L++ L+ + +LD+Q PP V VT H L+C A ++YP I + W +
Sbjct: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLK 241
Query: 242 AGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWE 296
+ EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+H L QPL+V WE
Sbjct: 242 DKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE 298
Query: 297 AS 298
S
Sbjct: 299 PS 300
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 197 bits (502), Expect = 7e-51
Identities = 117/307 (38%), Positives = 166/307 (54%), Gaps = 15/307 (4%)
Query: 1 MVRMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFR 60
M M P L LLLL G + G +S+ Y +T +S+ P F A+G ++D QF R
Sbjct: 1 MAVMAPRTL-LLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVR 59
Query: 61 YNSK--DRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVL 117
++S ++ +P W + EG E W Q+++ KA+ L + YYN S GSH +
Sbjct: 60 FDSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTI 119
Query: 118 QGRFGCEIENNRSSGAFWKYY----YDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPV 173
Q +GC++ S G F + Y YDGKDYI N+++ +W D AAQITK+KWEA
Sbjct: 120 QIMYGCDVG---SDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHE 176
Query: 174 YVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPG 233
++ +AYL+ C LR+YL+ K L R DPP +T H + L+C A FYP
Sbjct: 177 -AEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPA 235
Query: 234 KIDVHWTRAGE--VQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPL 291
+I + W R GE Q+ EL + G+GT+Q W V VP + Y+CHVQH L +PL
Sbjct: 236 EITLTWQRDGEDQTQDTEL-VETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPL 294
Query: 292 VVPWEAS 298
+ WE S
Sbjct: 295 TLRWELS 301
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 191 bits (486), Expect = 5e-49
Identities = 109/294 (37%), Positives = 158/294 (53%), Gaps = 8/294 (2%)
Query: 11 LLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDR--KS 68
LLLL G + G +SL Y T +S+ P + A+ ++D QF R++S +
Sbjct: 7 LLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRM 66
Query: 69 QPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVLQGRFGCEI-E 126
+P W + EG + W+ + KA L++++ YN S GSH LQG GC++
Sbjct: 67 EPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGP 126
Query: 127 NNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEEC 186
+ R + ++ YDGKDYI N+++ +W D AQIT++ +EAE Y + + YLE EC
Sbjct: 127 DGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE-YAEEFRTYLEGEC 185
Query: 187 PATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGE-- 244
LR+YL+ K L R DPP V H + L+C A FYP +I + W R GE
Sbjct: 186 LELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ 245
Query: 245 VQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298
Q+ EL + G+GT+Q W V VPP + Y+CHVQH L QPL++ WE S
Sbjct: 246 TQDTEL-VETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQS 298
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 191 bits (486), Expect = 5e-49
Identities = 109/294 (37%), Positives = 158/294 (53%), Gaps = 8/294 (2%)
Query: 11 LLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDR--KS 68
LLLL G + G +SL Y T +S+ P + A+ ++D QF R++S +
Sbjct: 7 LLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRM 66
Query: 69 QPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVLQGRFGCEI-E 126
+P W + EG + W+ + KA L++++ YN S GSH LQG GC++
Sbjct: 67 EPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGP 126
Query: 127 NNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEEC 186
+ R + ++ YDGKDYI N+++ +W D AQIT++ +EAE Y + + YLE EC
Sbjct: 127 DGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE-YAEEFRTYLEGEC 185
Query: 187 PATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGE-- 244
LR+YL+ K L R DPP V H + L+C A FYP +I + W R GE
Sbjct: 186 LELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ 245
Query: 245 VQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298
Q+ EL + G+GT+Q W V VPP + Y+CHVQH L QPL++ WE S
Sbjct: 246 TQDTEL-VETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQS 298
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 191 bits (484), Expect = 9e-49
Identities = 112/303 (36%), Positives = 162/303 (53%), Gaps = 7/303 (2%)
Query: 1 MVRMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFR 60
MV M P L LLL G E G +S+ Y +S+ P F A+G ++D QF R
Sbjct: 1 MVVMAPRTL-FLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVR 59
Query: 61 YNSKDR--KSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGS-HVL 117
++S + +P W + EG E W+++++ KA L+ + YYN S S H L
Sbjct: 60 FDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTL 119
Query: 118 QGRFGCEI-ENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQ 176
Q GC++ + R + +Y YDGKDY+ N+++ +W D AAQI+K+K EA V Q
Sbjct: 120 QWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQ 179
Query: 177 RAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKID 236
R +AYLE C L +YL+ K +L R DPP VT H + L+C A FYP +I
Sbjct: 180 R-RAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEII 238
Query: 237 VHWTRAGEVQEPELR-GDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPW 295
+ W R GE Q ++ + G+GT+Q W V VP + Y+CHVQH L +PL++ W
Sbjct: 239 LTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRW 298
Query: 296 EAS 298
+ S
Sbjct: 299 KQS 301
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 185 bits (469), Expect = 5e-47
Identities = 102/276 (36%), Positives = 150/276 (54%), Gaps = 6/276 (2%)
Query: 26 GRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDR--KSQPMGLWRQVEGMEDW 83
G +SL Y YT +S+ P F ++G ++D QF R++S + +P W + EG E W
Sbjct: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
Query: 84 KQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVLQGRFGCEI-ENNRSSGAFWKYYYDG 141
+ +++ K F L + YYN S GSH LQ +GC++ + R F + YDG
Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
Query: 142 KDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNIL 201
+DYI N+++ +W D AAQITK+K EA +R + YLE C LR+YL+ K+ L
Sbjct: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGA-AERQRNYLEGRCVEGLRRYLETGKDAL 216
Query: 202 DRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQEPELR-GDVLHNGNG 260
R DPP VT H + L+C A FYP +I + W R GE Q ++ + +G+G
Sbjct: 217 LRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDG 276
Query: 261 TYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWE 296
T+Q W + VP + Y+C VQH L +PL + WE
Sbjct: 277 TFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWE 312
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 183 bits (465), Expect = 1e-46
Identities = 107/294 (36%), Positives = 158/294 (53%), Gaps = 8/294 (2%)
Query: 11 LLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSK--DRKS 68
LLLL G E +S+ Y T +S+ P F ++G ++D QF R++S +
Sbjct: 10 LLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRG 69
Query: 69 QPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDS-NGSHVLQGRFGCEI-E 126
+P W + EG E W +++Q K + +L+++ YYN S +GSH LQ GC++
Sbjct: 70 EPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGCDLGP 129
Query: 127 NNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEEC 186
+ R + + YDGKDYI N+++ +W D AAQIT++K EA ++ +AYLE C
Sbjct: 130 DGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARA-AEQLRAYLEGTC 188
Query: 187 PATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGE-- 244
LR+YL+ K L R +PP VT H + L+C A FYP +I + W R GE
Sbjct: 189 VEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQ 248
Query: 245 VQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298
Q+ EL + G+GT+Q W V VP Y+CH+QH L +PL + WE S
Sbjct: 249 TQDTEL-VETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPS 301
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 183 bits (465), Expect = 1e-46
Identities = 109/302 (36%), Positives = 164/302 (54%), Gaps = 25/302 (8%)
Query: 3 RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62
R P LL LL+LL AV Q +SL Y++ G S+ + F+ALG ++D F Y+
Sbjct: 4 RARPALL-LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYD 62
Query: 63 SKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRF 121
+ R+ +P W + W Q SQ K + +F I+E +N S SH LQ
Sbjct: 63 HESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVIL 122
Query: 122 GCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAY 181
GCE++ + S+ +WKY YDG+D++EF + W +P A TK +WE + ++ +AY
Sbjct: 123 GCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
Query: 182 LEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTR 241
LE +CPA L++ L+ + +LD+Q VT+ L+C A ++YP I + W +
Sbjct: 183 LERDCPAQLQQLLELGRGVLDQQ------VTT---------LRCRALNYYPQNITMKWLK 227
Query: 242 AGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWE 296
+ EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+H L QPL+V WE
Sbjct: 228 DKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE 284
Query: 297 AS 298
S
Sbjct: 285 PS 286
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 182 bits (461), Expect = 4e-46
Identities = 106/294 (36%), Positives = 163/294 (55%), Gaps = 6/294 (2%)
Query: 8 LLSLLLLLGPAVPQENQDGR-YSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDR 66
L++ LL L + ++ D R +SL Y G+S + VP F ++G ++ Y+S R
Sbjct: 4 LMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTR 63
Query: 67 KSQPMGLWRQVEGMED-WKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEI 125
+ +P W D W++ +QL + + +F LK + +YN S GSH Q GCE+
Sbjct: 64 QKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS-GSHTYQRMIGCEL 122
Query: 126 ENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEE 185
+ S+ F +Y YDG+D++ FNK+ +W+ D A KQ WEA + K +LEEE
Sbjct: 123 LEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEE 182
Query: 186 CPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGE- 244
C A L+++L+Y K+ L R +PP V V + L C A+ FYP +I + W + GE
Sbjct: 183 CIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEE 242
Query: 245 -VQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEA 297
VQE + GD+L +G+GTYQ+W + + PQ + YSCHV+H + L VP E+
Sbjct: 243 IVQEIDY-GDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQES 295
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 178 bits (452), Expect = 4e-45
Identities = 95/255 (37%), Positives = 142/255 (55%), Gaps = 10/255 (3%)
Query: 50 LGSLNDLQFFRYNSKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYY 108
LG ++D F Y+ + R+ +P W + W Q SQ K + +F I+E +
Sbjct: 27 LGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENH 86
Query: 109 NDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKW 168
N S SH LQ GCE++ + S+ +WKY YDG+D++EF + W +P A TK +W
Sbjct: 87 NHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEW 146
Query: 169 EAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAY 228
E + ++ +AYLE +CPA L++ L+ + +LD+Q PP V VT H L+C A
Sbjct: 147 ERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVT-HHVTSSVTTLRCRAL 205
Query: 229 DFYPGKIDVHWTRAGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQ 283
++YP I + W + + EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+
Sbjct: 206 NYYPQNITMKWLKDKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVE 262
Query: 284 HSSLAQPLVVPWEAS 298
H L QPL+V WE S
Sbjct: 263 HPGLDQPLIVIWEPS 277
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 178 bits (452), Expect = 4e-45
Identities = 102/294 (34%), Positives = 158/294 (53%), Gaps = 9/294 (3%)
Query: 10 SLLLLLGPAVP-QENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKS 68
+LLLLL A+ + G +SL Y +T +S+ P F ++G ++D QF R+++
Sbjct: 5 TLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASP 64
Query: 69 Q--PMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVLQGRFGCEI 125
+ P W + EG E W ++++ + IF L+ + YYN S GSH LQ GCE+
Sbjct: 65 RMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCEL 124
Query: 126 -ENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEE 184
+ R + ++ YDGKDY+ N+++ +W D AAQI++QK + + +AYLE+
Sbjct: 125 GPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDASEAEHQRAYLED 183
Query: 185 ECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGE 244
C L KYL+ K L +PP VT H + L+C A FYP +I + W + GE
Sbjct: 184 TCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGE 243
Query: 245 --VQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWE 296
Q+ EL + G+GT+Q W V VP + Y+CHVQH L +P+ + W+
Sbjct: 244 GHTQDTEL-VETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWK 296
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 157 bits (396), Expect = 1e-38
Identities = 77/190 (40%), Positives = 113/190 (59%), Gaps = 9/190 (4%)
Query: 114 SHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPV 173
SH LQ GCE++ + S+ +WKY YDG+D++EF + W +P A TK +WE +
Sbjct: 27 SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKI 86
Query: 174 YVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPG 233
++ +AYLE +CPA L++ L+ + +LD+Q PP V VT H L+C A ++YP
Sbjct: 87 RARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVT-HHVTSSVTTLRCRALNYYPQ 145
Query: 234 KIDVHWTRAGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLA 288
I + W + + EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+H L
Sbjct: 146 NITMKWLKDKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLD 202
Query: 289 QPLVVPWEAS 298
QPL+V WE S
Sbjct: 203 QPLIVIWEPS 212
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 142 bits (358), Expect = 4e-34
Identities = 73/190 (38%), Positives = 110/190 (57%), Gaps = 23/190 (12%)
Query: 114 SHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPV 173
SH LQ GCE++ + S+ +WKY YDG+D++EF + W +P A TK +WE +
Sbjct: 27 SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKI 86
Query: 174 YVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPG 233
++ +AYLE +CPA L++ L+ + +LD+Q VT+ L+C A ++YP
Sbjct: 87 RARQNRAYLERDCPAQLQQLLELGRGVLDQQ------VTT---------LRCRALNYYPQ 131
Query: 234 KIDVHWTRAGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLA 288
I + W + + EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+H L
Sbjct: 132 NITMKWLKDKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLD 188
Query: 289 QPLVVPWEAS 298
QPL+V WE S
Sbjct: 189 QPLIVIWEPS 198
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 122 bits (307), Expect = 3e-28
Identities = 84/298 (28%), Positives = 141/298 (47%), Gaps = 13/298 (4%)
Query: 3 RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62
R P L LLL L P + SL Y T +S PAF G L Q+ YN
Sbjct: 5 RPQPWALGLLLFLLPG--SLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYN 62
Query: 63 SKDRKSQPMGLW---RQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQG 119
S +++P G W QV W++++ + +E +F+E K + G + LQG
Sbjct: 63 SLRGEAEPCGAWVWENQVSWY--WEKETTDLRIKEKLFLEAFKAL-----GGKGPYTLQG 115
Query: 120 RFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAK 179
GCE+ + +S K+ +G++++ F+ + W P A Q+W+ + +
Sbjct: 116 LLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKEL 175
Query: 180 AYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHW 239
+L CP LR++L+ + L+ ++PPS+ + + + L C A+ FYP ++ + +
Sbjct: 176 TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRF 235
Query: 240 TRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEA 297
R G + +GD N +G++ + + V D Y C VQH+ LAQPL V E+
Sbjct: 236 LRNG-LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELES 292
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 122 bits (307), Expect = 3e-28
Identities = 84/298 (28%), Positives = 141/298 (47%), Gaps = 13/298 (4%)
Query: 3 RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62
R P L LLL L P + SL Y T +S PAF G L Q+ YN
Sbjct: 5 RPQPWALGLLLFLLPG--SLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYN 62
Query: 63 SKDRKSQPMGLW---RQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQG 119
S +++P G W QV W++++ + +E +F+E K + G + LQG
Sbjct: 63 SLRGEAEPCGAWVWENQVSWY--WEKETTDLRIKEKLFLEAFKAL-----GGKGPYTLQG 115
Query: 120 RFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAK 179
GCE+ + +S K+ +G++++ F+ + W P A Q+W+ + +
Sbjct: 116 LLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKEL 175
Query: 180 AYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHW 239
+L CP LR++L+ + L+ ++PPS+ + + + L C A+ FYP ++ + +
Sbjct: 176 TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRF 235
Query: 240 TRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEA 297
R G + +GD N +G++ + + V D Y C VQH+ LAQPL V E+
Sbjct: 236 LRNG-LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELES 292
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 113 bits (283), Expect = 2e-25
Identities = 68/199 (34%), Positives = 106/199 (53%), Gaps = 5/199 (2%)
Query: 11 LLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDR--KS 68
LLLL G + G +SL Y T +S+ P + A+ ++D QF R++S +
Sbjct: 7 LLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRM 66
Query: 69 QPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVLQGRFGCEI-E 126
+P W + EG + W+ + KA L++++ YN S GSH LQG GC++
Sbjct: 67 EPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGP 126
Query: 127 NNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEEC 186
+ R + ++ YDGKDYI N+++ +W D AQIT++ +EAE Y + + YLE EC
Sbjct: 127 DGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE-YAEEFRTYLEGEC 185
Query: 187 PATLRKYLKYSKNILDRQD 205
LR+YL+ K L R +
Sbjct: 186 LELLRRYLENGKETLQRAE 204
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 104 bits (260), Expect = 8e-23
Identities = 80/286 (27%), Positives = 127/286 (44%), Gaps = 12/286 (4%)
Query: 8 LLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRK 67
+L L + P P +SL Y LS+ F A G L+ F RY+ + R+
Sbjct: 6 VLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRR 65
Query: 68 SQPMGLWRQ-VEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIE 126
++P G W + V G + W +++ TL I + G H LQ CEI
Sbjct: 66 AKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKD---QKGGLHSLQEIRVCEIH 122
Query: 127 NNRSSGAFWKYYYDGKDYIEFNKEIP-AWVPFDPAAQITKQK----WEAEPVYVQRAKAY 181
+ S+ +YYDG+ ++ N E + VP AQ W+ + + +
Sbjct: 123 EDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRA 182
Query: 182 LEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTR 241
++ +C L++YLK S + R PP V VT + + C A FYP I + W +
Sbjct: 183 MQADCLQKLQRYLK-SGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQ 241
Query: 242 AGEVQEPELR--GDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHS 285
G + GDVL +GNGTYQ+WV + + ++C+++HS
Sbjct: 242 DGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHS 287
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 97.8 bits (242), Expect = 1e-20
Identities = 82/288 (28%), Positives = 129/288 (44%), Gaps = 13/288 (4%)
Query: 6 PVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKD 65
PV L LL + P P +SL Y T LS F L+ F R + +
Sbjct: 5 PVFL-LLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQK 63
Query: 66 RKSQPMGLWRQ-VEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCE 124
+++P G W + V G + W ++++ TL I + G H LQ CE
Sbjct: 64 CRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKD---QKEGLHSLQEIRVCE 120
Query: 125 IENNRSSGAFWKYYYDGKDYIEFNKEIPAW-VPFDPAAQI----TKQKWEAEPVYVQRAK 179
I + S+ + +YYDG+ ++ N E W +P AQ + + + + +
Sbjct: 121 IHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHY 180
Query: 180 AYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHW 239
+ +C LR+YLK S +L R PP V VT +A + C A FYP I + W
Sbjct: 181 HAMHADCLQELRRYLK-SGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSW 239
Query: 240 TRAGEVQEPELR--GDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHS 285
+ G + + GDVL +GNGTYQ+WV + + ++C+++HS
Sbjct: 240 RQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHS 287
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 87.8 bits (216), Expect = 1e-17
Identities = 82/306 (26%), Positives = 133/306 (43%), Gaps = 28/306 (9%)
Query: 8 LLSLLLLLGPAVPQE-NQDGRYSLTYIYTGLSKHVEDVPAFQ--------ALGSLNDLQF 58
+L LLL L +P + N DG + LS HV + +F G L+DLQ
Sbjct: 1 MLFLLLPLLAVLPGDGNADG------LKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQT 54
Query: 59 FRYNSKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHV- 116
++S + W + E+WK+ L + R + + + I Y ++ +
Sbjct: 55 HTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRT---IRSFEGIRRYAHELQFEYPF 111
Query: 117 -LQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYV 175
+Q GCE+ + + SG+F + Y G D++ F +W+P+ A + K +
Sbjct: 112 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNMAKHFCKVLNQNQ 169
Query: 176 QR---AKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKK-KLKCLAYDFY 231
L + CP + L K L RQ P ++ +PG +L C FY
Sbjct: 170 HENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFY 229
Query: 232 PGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSL-AQP 290
P + V W R + Q+ RGD+L + +GT+ + V + A SC V+HSSL Q
Sbjct: 230 PKPVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQD 289
Query: 291 LVVPWE 296
+V+ WE
Sbjct: 290 IVLYWE 295
>gi|150418002 major histocompatibility complex, class II, DQ beta 1
precursor [Homo sapiens]
Length = 261
Score = 85.5 bits (210), Expect = 5e-17
Identities = 61/228 (26%), Positives = 100/228 (43%), Gaps = 21/228 (9%)
Query: 83 WKQ----DSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSSGAF-WKY 137
WK+ L+ A + + L ++ DS V Q + C N +Y
Sbjct: 3 WKKALRIPGDLRVATVTLMLAMLSSLLAEGRDSPEDFVFQFKGMCYFTNGTERVRLVTRY 62
Query: 138 YYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYS 197
Y+ ++Y F+ ++ + P + + W ++ ++ +A L+ C Y
Sbjct: 63 IYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCR---HNYEVAF 119
Query: 198 KNILDRQDPPSVVVTSH--QAPGEKKKLKCLAYDFYPGKIDVHWTR------AGEVQEPE 249
+ IL R+ P+V ++ +A L C DFYPG+I V W R AG V P
Sbjct: 120 RGILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPL 179
Query: 250 LRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEA 297
+R NG+ T+Q V++ + PQ Y+CHV+H SL P+ V W A
Sbjct: 180 IR-----NGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 222
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 82.0 bits (201), Expect = 6e-16
Identities = 58/218 (26%), Positives = 94/218 (43%), Gaps = 17/218 (7%)
Query: 89 LQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSS-GAFWKYYYDGKDYIEF 147
L+ A + + L V DS V Q + C N +Y Y+ ++Y F
Sbjct: 13 LRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNREEYARF 72
Query: 148 NKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPP 207
+ ++ + P + W ++ ++R +A L+ C Y + L R+ P
Sbjct: 73 DSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCR---HNYQLELRTTLQRRVEP 129
Query: 208 SVVVTSH--QAPGEKKKLKCLAYDFYPGKIDVHWTR------AGEVQEPELRGDVLHNGN 259
+V ++ +A L C DFYP +I V W R G V P +R NG+
Sbjct: 130 TVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIR-----NGD 184
Query: 260 GTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEA 297
T+Q V++ + PQ Y+CHV+H SL P++V W A
Sbjct: 185 WTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRA 222
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 82.0 bits (201), Expect = 6e-16
Identities = 58/218 (26%), Positives = 94/218 (43%), Gaps = 17/218 (7%)
Query: 89 LQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSS-GAFWKYYYDGKDYIEF 147
L+ A + + L V DS V Q + C N +Y Y+ ++Y F
Sbjct: 13 LRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNREEYARF 72
Query: 148 NKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPP 207
+ ++ + P + W ++ ++R +A L+ C Y + L R+ P
Sbjct: 73 DSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCR---HNYQLELRTTLQRRVEP 129
Query: 208 SVVVTSH--QAPGEKKKLKCLAYDFYPGKIDVHWTR------AGEVQEPELRGDVLHNGN 259
+V ++ +A L C DFYP +I V W R G V P +R NG+
Sbjct: 130 TVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIR-----NGD 184
Query: 260 GTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEA 297
T+Q V++ + PQ Y+CHV+H SL P++V W A
Sbjct: 185 WTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRA 222
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 81.6 bits (200), Expect = 7e-16
Identities = 58/218 (26%), Positives = 94/218 (43%), Gaps = 17/218 (7%)
Query: 89 LQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSS-GAFWKYYYDGKDYIEF 147
L+ A + + L V DS V Q + C N +Y Y+ ++Y F
Sbjct: 13 LRVATVTLMLAMLSTPVAEGRDSPEDFVFQFKGMCYFTNGTERVRGVTRYIYNREEYARF 72
Query: 148 NKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPP 207
+ ++ + P + W ++ ++R +A ++ C Y + L R+ P
Sbjct: 73 DSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCR---HNYQLELRTTLQRRVEP 129
Query: 208 SVVVTSH--QAPGEKKKLKCLAYDFYPGKIDVHWTR------AGEVQEPELRGDVLHNGN 259
+V ++ +A L C DFYP +I V W R AG V P +R NG+
Sbjct: 130 TVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIR-----NGD 184
Query: 260 GTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEA 297
T+Q V++ + PQ Y+CHV+H SL P+ V W A
Sbjct: 185 WTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 222
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 79.0 bits (193), Expect = 5e-15
Identities = 43/117 (36%), Positives = 61/117 (52%), Gaps = 8/117 (6%)
Query: 187 PATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQ 246
PA L L + + R P +V +H L+C A ++YP I + W + +
Sbjct: 7 PALLLLMLLQTAVLQGRLLLPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPM 66
Query: 247 -----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298
EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+H L QPL+V WE S
Sbjct: 67 DAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 120
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 78.6 bits (192), Expect = 6e-15
Identities = 41/98 (41%), Positives = 55/98 (56%), Gaps = 9/98 (9%)
Query: 206 PPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQ-----EPELRGDVLHNGNG 260
PP V VT H L+C A ++YP I + W + + EP+ DVL NG+G
Sbjct: 115 PPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPK---DVLPNGDG 170
Query: 261 TYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298
TYQ W+ +AVPP + Y+C V+H L QPL+V WE S
Sbjct: 171 TYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 208
Score = 46.6 bits (109), Expect = 3e-05
Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Query: 3 RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62
R P LL LL+LL AV Q +SL Y++ G S+ + F+ALG ++D F Y+
Sbjct: 4 RARPALL-LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYD 62
Query: 63 SKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYYNDS 111
+ R+ +P W + W Q SQ K + +F I+E +N S
Sbjct: 63 HESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS 112
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 78.2 bits (191), Expect = 8e-15
Identities = 69/260 (26%), Positives = 109/260 (41%), Gaps = 19/260 (7%)
Query: 50 LGSLNDLQFFRYNSKDRKSQPMGLWRQ-VEGMEDWKQDSQLQKAREDIFMETLKDIVEYY 108
L L +LQ +++ + + W Q + W+ + + F +K+ +
Sbjct: 47 LAWLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKML 106
Query: 109 NDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFN-------KEIPAWVPFDPAA 161
S LQ GCE+ +S F+ + GKD + F +E P WV A
Sbjct: 107 RLSYPLE-LQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNL--AI 163
Query: 162 QITKQ-KWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEK 220
Q+ Q KW E V + L CP + L+ K+ L +Q P ++ +PG
Sbjct: 164 QVLNQDKWTRETV-----QWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPG 218
Query: 221 KKLK-CLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYS 279
+ L C FYP + V W R + Q+ GD+L N + T+ + V + A S
Sbjct: 219 RLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLS 278
Query: 280 CHVQHSSL-AQPLVVPWEAS 298
C V+HSSL Q +V+ W S
Sbjct: 279 CRVKHSSLEGQDIVLYWGGS 298
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 73.2 bits (178), Expect = 3e-13
Identities = 35/81 (43%), Positives = 49/81 (60%), Gaps = 8/81 (9%)
Query: 223 LKCLAYDFYPGKIDVHWTRAGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAP 277
L+C A ++YP I + W + + EP+ DVL NG+GTYQ W+ +AVPP +
Sbjct: 117 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQR 173
Query: 278 YSCHVQHSSLAQPLVVPWEAS 298
Y+C V+H L QPL+V WE S
Sbjct: 174 YTCQVEHPGLDQPLIVIWEPS 194
Score = 46.6 bits (109), Expect = 3e-05
Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Query: 3 RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62
R P LL LL+LL AV Q +SL Y++ G S+ + F+ALG ++D F Y+
Sbjct: 4 RARPALL-LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYD 62
Query: 63 SKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYYNDS 111
+ R+ +P W + W Q SQ K + +F I+E +N S
Sbjct: 63 HESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS 112
>gi|110618227 CD1C antigen precursor [Homo sapiens]
Length = 333
Score = 72.8 bits (177), Expect = 3e-13
Identities = 53/190 (27%), Positives = 85/190 (44%), Gaps = 18/190 (9%)
Query: 117 LQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQ---------K 167
+Q + GCE+ + +S F++ ++G D + F WVP + + +
Sbjct: 114 VQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQYE 171
Query: 168 WEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLK-CL 226
E VY + CP L L K + RQ P ++S + G + L C
Sbjct: 172 GVTETVY-----NLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCH 226
Query: 227 AYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSS 286
A FYP + V W R + Q GD+L N +GT+ V++ V ++ A SC V+HSS
Sbjct: 227 ASGFYPKPVWVTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSS 286
Query: 287 L-AQPLVVPW 295
L Q +++ W
Sbjct: 287 LGGQDIILYW 296
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,129,258
Number of Sequences: 37866
Number of extensions: 634760
Number of successful extensions: 1662
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 1455
Number of HSP's gapped (non-prelim): 124
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.