Search of human proteins with 44889963

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|44889963 CD163 antigen isoform b [Homo sapiens]
         (1121 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|44889963 CD163 antigen isoform b [Homo sapiens]                   2403   0.0  
gi|44662834 CD163 antigen isoform a [Homo sapiens]                   2387   0.0  
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H...  1321   0.0  
gi|148539844 deleted in malignant brain tumors 1 isoform c precu...   902   0.0  
gi|148539842 deleted in malignant brain tumors 1 isoform b precu...   901   0.0  
gi|148539840 deleted in malignant brain tumors 1 isoform a precu...   788   0.0  
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]     783   0.0  
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]     721   0.0  
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]            352   1e-96
gi|18152779 scavenger receptor cysteine rich domain containing, ...   338   2e-92
gi|4506143 neurotrypsin precursor [Homo sapiens]                      329   1e-89
gi|5174411 CD5 molecule-like [Homo sapiens]                           260   4e-69
gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]           255   2e-67
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]              213   8e-55
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]             213   8e-55
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]             212   2e-54
gi|194018748 CD6 molecule [Homo sapiens]                              201   2e-51
gi|5031863 galectin 3 binding protein [Homo sapiens]                  135   3e-31
gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo...   123   1e-27
gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]       119   2e-26
gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]             113   1e-24
gi|5803080 macrophage receptor with collagenous structure [Homo ...   110   1e-23
gi|166197668 CD5 molecule [Homo sapiens]                               71   7e-12
gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo...    63   1e-09
gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]                42   0.002
gi|119392081 complement factor I preproprotein [Homo sapiens]          42   0.003
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...    38   0.062
gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo sap...    38   0.062
gi|223942069 enterokinase precursor [Homo sapiens]                     37   0.10 
gi|56711322 ring finger protein 43 [Homo sapiens]                      35   0.52 

>gi|44889963 CD163 antigen isoform b [Homo sapiens]
          Length = 1121

 Score = 2403 bits (6228), Expect = 0.0
 Identities = 1121/1121 (100%), Positives = 1121/1121 (100%)

Query: 1    MSKLRMVLLEDSGSADFRRHFVNLSPFTITVVLLLSACFVTSSLGGTDKELRLVDGENKC 60
            MSKLRMVLLEDSGSADFRRHFVNLSPFTITVVLLLSACFVTSSLGGTDKELRLVDGENKC
Sbjct: 1    MSKLRMVLLEDSGSADFRRHFVNLSPFTITVVLLLSACFVTSSLGGTDKELRLVDGENKC 60

Query: 61   SGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSC 120
            SGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSC
Sbjct: 61   SGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSC 120

Query: 121  RGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMCSGRIEIKFQGRW 180
            RGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMCSGRIEIKFQGRW
Sbjct: 121  RGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMCSGRIEIKFQGRW 180

Query: 181  GTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKH 240
            GTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKH
Sbjct: 181  GTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKH 240

Query: 241  QGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDA 300
            QGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDA
Sbjct: 241  QGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDA 300

Query: 301  AVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNED 360
            AVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNED
Sbjct: 301  AVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNED 360

Query: 361  AGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSAL 420
            AGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSAL
Sbjct: 361  AGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSAL 420

Query: 421  KTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRL 480
            KTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRL
Sbjct: 421  KTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRL 480

Query: 481  VGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQI 540
            VGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQI
Sbjct: 481  VGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQI 540

Query: 541  WAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKT 600
            WAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKT
Sbjct: 541  WAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKT 600

Query: 601  LGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMG 660
            LGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMG
Sbjct: 601  LGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMG 660

Query: 661  DCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLR 720
            DCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLR
Sbjct: 661  DCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLR 720

Query: 721  LVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGP 780
            LVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGP
Sbjct: 721  LVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGP 780

Query: 781  IWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRLE 840
            IWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRLE
Sbjct: 781  IWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRLE 840

Query: 841  VFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPD 900
            VFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPD
Sbjct: 841  VFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPD 900

Query: 901  TLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDL 960
            TLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDL
Sbjct: 901  TLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDL 960

Query: 961  DDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGH 1020
            DDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGH
Sbjct: 961  DDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGH 1020

Query: 1021 KEDAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQR 1080
            KEDAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQR
Sbjct: 1021 KEDAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQR 1080

Query: 1081 LAVSSRGENLVHQIQYREMNSCLNADDLDLMNSSGGHSEPH 1121
            LAVSSRGENLVHQIQYREMNSCLNADDLDLMNSSGGHSEPH
Sbjct: 1081 LAVSSRGENLVHQIQYREMNSCLNADDLDLMNSSGGHSEPH 1121


>gi|44662834 CD163 antigen isoform a [Homo sapiens]
          Length = 1156

 Score = 2387 bits (6185), Expect = 0.0
 Identities = 1115/1119 (99%), Positives = 1115/1119 (99%)

Query: 1    MSKLRMVLLEDSGSADFRRHFVNLSPFTITVVLLLSACFVTSSLGGTDKELRLVDGENKC 60
            MSKLRMVLLEDSGSADFRRHFVNLSPFTITVVLLLSACFVTSSLGGTDKELRLVDGENKC
Sbjct: 1    MSKLRMVLLEDSGSADFRRHFVNLSPFTITVVLLLSACFVTSSLGGTDKELRLVDGENKC 60

Query: 61   SGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSC 120
            SGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSC
Sbjct: 61   SGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSC 120

Query: 121  RGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMCSGRIEIKFQGRW 180
            RGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMCSGRIEIKFQGRW
Sbjct: 121  RGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMCSGRIEIKFQGRW 180

Query: 181  GTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKH 240
            GTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKH
Sbjct: 181  GTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKH 240

Query: 241  QGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDA 300
            QGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDA
Sbjct: 241  QGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDA 300

Query: 301  AVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNED 360
            AVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNED
Sbjct: 301  AVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNED 360

Query: 361  AGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSAL 420
            AGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSAL
Sbjct: 361  AGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSAL 420

Query: 421  KTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRL 480
            KTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRL
Sbjct: 421  KTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRL 480

Query: 481  VGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQI 540
            VGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQI
Sbjct: 481  VGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQI 540

Query: 541  WAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKT 600
            WAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKT
Sbjct: 541  WAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKT 600

Query: 601  LGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMG 660
            LGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMG
Sbjct: 601  LGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMG 660

Query: 661  DCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLR 720
            DCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLR
Sbjct: 661  DCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLR 720

Query: 721  LVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGP 780
            LVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGP
Sbjct: 721  LVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGP 780

Query: 781  IWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRLE 840
            IWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRLE
Sbjct: 781  IWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRLE 840

Query: 841  VFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPD 900
            VFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPD
Sbjct: 841  VFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPD 900

Query: 901  TLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDL 960
            TLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDL
Sbjct: 901  TLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDL 960

Query: 961  DDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGH 1020
            DDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGH
Sbjct: 961  DDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGH 1020

Query: 1021 KEDAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQR 1080
            KEDAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQR
Sbjct: 1021 KEDAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQR 1080

Query: 1081 LAVSSRGENLVHQIQYREMNSCLNADDLDLMNSSGGHSE 1119
            LAVSSRGENLVHQIQYREMNSCLNADDLDLMNSS    E
Sbjct: 1081 LAVSSRGENLVHQIQYREMNSCLNADDLDLMNSSENSHE 1119


>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
            sapiens]
          Length = 1453

 Score = 1321 bits (3419), Expect = 0.0
 Identities = 598/1065 (56%), Positives = 759/1065 (71%), Gaps = 12/1065 (1%)

Query: 46   GTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWAN 105
            G D ELRL DG N CSGRVEV++ E+W T+C+  W  E   V+C QLGCP ++     A 
Sbjct: 364  GADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAK 423

Query: 106  SSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGG 165
             S  +  IW++ +SC GNESALWDC +DG  K + C  + DAGV CSD ++L++RL    
Sbjct: 424  PSNEARDIWINSISCTGNESALWDCTYDGKAKRT-CFRRSDAGVICSDKADLDLRLVGAH 482

Query: 166  NMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDD 225
            + C GR+E+K+QG WGTVC D ++  +A+V+C+QL CG  +   G + F E SGPIW DD
Sbjct: 483  SPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDD 542

Query: 226  LICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQG 285
            + C GNES +W+C+H GWGKHNC H ED  V CS  A   LRLV G   CSGRLEV FQG
Sbjct: 543  VSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVYFQG 602

Query: 286  EWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQC 345
             WGT+CDDGW+S  AAV C QL CP+++  +G  NAS G+G IWLD VSC G E  +W C
Sbjct: 603  RWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSC 662

Query: 346  KHHEWGKHYCNHNEDAGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLK 405
            ++  WG + C+H+ED GV CSD SD+ELRL GG SRCAG VEV +Q  +G +C  GWG+ 
Sbjct: 663  RNSGWGNNDCSHSEDVGVICSDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMN 722

Query: 406  EADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHY 465
             A+VVCRQL CGSA++ S + +   +  +  +  S C G E SLWDC  W+W    C   
Sbjct: 723  IAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLN 782

Query: 466  EEAKITCSAHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVV 525
             EA + CSAHR+PRLVG D+PCSGRVEVKH DTW S+CDSDFSL AA+VLCREL CG  +
Sbjct: 783  MEASLICSAHRQPRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAI 842

Query: 526  SILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRL 585
            S+  G HFG+GNG  WAE+FQCEG E+HL+LCP+   PE TC HSR+VGVVCSRYT++RL
Sbjct: 843  SLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDVRL 902

Query: 586  VNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQI 645
            VNGK+ C+G+VE+  LG WGSLC++HWD EDA VLC+QL CG ALST GG   G+ + ++
Sbjct: 903  VNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRV 962

Query: 646  WRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTI 705
            W H FHC G E  + +C +T LGA  C      SVIC+G+ +Q L  C ++   P    +
Sbjct: 963  WGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAV 1022

Query: 706  PEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEA 765
            PE SA+ C+E  +LRLV+G  RCAGRVEIYH+G WGTICDD WDLSDAHVVC++LGCG A
Sbjct: 1023 PEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVA 1082

Query: 766  INATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLR 825
             NAT SAHFGEG+GPIWLD++ C G ES +WQC S GWGQ +CRHKEDAGVICSEF +LR
Sbjct: 1083 FNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTALR 1142

Query: 826  LTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMS 885
            L SE   E+CAGRLEVFYNG WG+VG+ +++    G+VCRQLGC + G ++ A L K  S
Sbjct: 1143 LYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGS 1202

Query: 886  IPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIW 945
              MWVD++QCPK   ++WQC S+PWE+R++SP+EETWITC+++IR++ G T CSGRVEIW
Sbjct: 1203 GFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDRIRVRGGDTECSGRVEIW 1262

Query: 946  HGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSL 1005
            H GSWGTVCDDSWDL +A+VVCQQLGCG AL A ++A FGQGTG IWL++++CKGNES L
Sbjct: 1263 HAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFL 1322

Query: 1006 WDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIF 1065
            WDC A+ WG S+CGHKEDA V C+  S++      +   SS   + I   I G++LL +F
Sbjct: 1323 WDCHAKPWGQSDCGHKEDAGVRCSGQSLK------SLNASSGHLALILSSIFGLLLLVLF 1376

Query: 1066 VALFFLTKKRRQRQR---LAVSSRGENLVHQIQYREMNSCLNADD 1107
            +   FLT  R Q+Q+   L VS+R    + +  + EM +CL  +D
Sbjct: 1377 I--LFLTWCRVQKQKHLPLRVSTRRRGSLEENLFHEMETCLKRED 1419



 Score =  785 bits (2026), Expect = 0.0
 Identities = 404/1032 (39%), Positives = 556/1032 (53%), Gaps = 40/1032 (3%)

Query: 6    MVLLEDSGSADFRRHFV--NLSPFTITVVLLLSACFVTSSLGGTDKELRLVDGENKCSGR 63
            M+L ++S   DF R     NL    +T +LLL++CF+ SS  GTD ELRLV+G+  CSG 
Sbjct: 1    MMLPQNSWHIDFGRCCCHQNLFSAVVTCILLLNSCFLISSFNGTDLELRLVNGDGPCSGT 60

Query: 64   VEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGN 123
            VEVK Q +WGTVC++GW+  A +V+C QLGCP +     +  +    G+IW+D VSC GN
Sbjct: 61   VEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCYGN 120

Query: 124  ESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTV 183
            ESALW+C+H  WG H NC H +D GV C   +NL +RL  G N CSGR+E+KFQ RWGT+
Sbjct: 121  ESALWECQHREWGSH-NCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERWGTI 179

Query: 184  CDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGW 243
            CDD +N++ A+V+CRQL C S+   SG  N      PIW DD++C GNE ALWNC+H+GW
Sbjct: 180  CDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGW 239

Query: 244  GKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303
            G H+C H ED  + C   +DL LRLV G   C GR+E++ QG WGT+C   W++  A V 
Sbjct: 240  GNHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVV 299

Query: 304  CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363
            CKQLGC TA+   G  +   G   +WLD VSC G+E  +W C+H       C H  D  V
Sbjct: 300  CKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSV 359

Query: 364  TCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTS 423
             CSDG+DLELRL  G + C+G VEV I      +CD+ W  ++A VVC+QLGC  ++  S
Sbjct: 360  ICSDGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGS 419

Query: 424  YQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS--AHREPRLV 481
             +     +A + W+   SC GNE++LWDC        TC    +A + CS  A  + RLV
Sbjct: 420  RRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLDLRLV 479

Query: 482  GGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIW 541
            G   PC GR+EVK+   WG++C   +S   A+V+C++L CG  + + G  +F E +G IW
Sbjct: 480  GAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIW 539

Query: 542  AEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE--IRLVNGKTPCEGRVELK 599
             ++  C G+ES++  C  +   +  C H  DV V CS      +RLV G   C GR+E+ 
Sbjct: 540  LDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVY 599

Query: 600  TLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHM 659
              G WG++C+  W+ + A V+C QL C  ++   G      G G+IW     C G E  +
Sbjct: 600  FQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDL 659

Query: 660  GDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQL 719
              C  +  G + C   +   VICS                                  +L
Sbjct: 660  WSCRNSGWGNNDCSHSEDVGVICSDASDM-----------------------------EL 690

Query: 720  RLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTG 779
            RLV G  RCAG+VE+  +G+ G +C + W ++ A VVCRQL CG AI  +   HF E T 
Sbjct: 691  RLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTL 750

Query: 780  PIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRL 839
             I +    C G E+ +W C    W Q  C    +A +ICS     RL    +   C+GR+
Sbjct: 751  HILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRLV--GADMPCSGRV 808

Query: 840  EVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGP 899
            EV +   W +V  S  S     V+CR+L C D   ++        +   W +  QC    
Sbjct: 809  EVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSE 868

Query: 900  DTLWQCPSSPWEKRLASPSEETWITCD--NKIRLQEGPTSCSGRVEIWHGGSWGTVCDDS 957
              L  CP     +     S E  + C     +RL  G + C G+VEI   G WG++CD  
Sbjct: 869  THLALCPIVQHPEDTCIHSREVGVVCSRYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTH 928

Query: 958  WDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSE 1017
            WD +DA+V+C+QL CG AL        G+ +  +W +   C GNES L +C     G   
Sbjct: 929  WDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPP 988

Query: 1018 CGHKEDAAVNCT 1029
            C H    +V CT
Sbjct: 989  CIHGNTVSVICT 1000



 Score =  255 bits (652), Expect = 1e-67
 Identities = 127/320 (39%), Positives = 171/320 (53%), Gaps = 10/320 (3%)

Query: 718  QLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEG 777
            +LRLVNG G C+G VE+  +G WGT+CDD W+ + + VVC+QLGC  +        FG+ 
Sbjct: 47   ELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSF---AMFRFGQA 103

Query: 778  T---GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREA 834
                G IWLD++ C G ES +W+C    WG  NC H ED GV C    +L L       +
Sbjct: 104  VTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNS 163

Query: 835  CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQ 894
            C+GR+EV +   WGT+     +  T  VVCRQLGC      +      A+  P+W+D++ 
Sbjct: 164  CSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDIL 223

Query: 895  CPKGPDTLWQCPSSPWEKRLASPSEETWITC----DNKIRLQEGPTSCSGRVEIWHGGSW 950
            C      LW C    W     S +E+  +TC    D ++RL  G   C GRVE+   G W
Sbjct: 224  CQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVELKIQGRW 283

Query: 951  GTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPA 1010
            GTVC   W+   A VVC+QLGCG AL          G+  +WL+ V C GNES LWDC  
Sbjct: 284  GTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRH 343

Query: 1011 RRWGHSECGHKEDAAVNCTD 1030
                + +C H+ D +V C+D
Sbjct: 344  SGTVNFDCLHQNDVSVICSD 363



 Score =  156 bits (394), Expect = 1e-37
 Identities = 74/202 (36%), Positives = 105/202 (51%), Gaps = 4/202 (1%)

Query: 835  CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQ 894
            C+G +EV + G WGTV     + T   VVC+QLGC     +            +W+D+V 
Sbjct: 57   CSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVS 116

Query: 895  CPKGPDTLWQCPSSPWEKRLASPSEETWITCDNK----IRLQEGPTSCSGRVEIWHGGSW 950
            C      LW+C    W        E+  + C  +    +RL +G  SCSGRVE+     W
Sbjct: 117  CYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERW 176

Query: 951  GTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPA 1010
            GT+CDD W+L+ A VVC+QLGC  +  +           PIWL+++ C+GNE +LW+C  
Sbjct: 177  GTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRH 236

Query: 1011 RRWGHSECGHKEDAAVNCTDIS 1032
            R WG+ +C H ED  + C D S
Sbjct: 237  RGWGNHDCSHNEDVTLTCYDSS 258


>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
            [Homo sapiens]
          Length = 2403

 Score =  902 bits (2331), Expect = 0.0
 Identities = 478/1133 (42%), Positives = 615/1133 (54%), Gaps = 152/1133 (13%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G+ +C GRVE+  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 102  LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 162  GPIALDDVRCSGHESYLWSCPHNGWLSH-NCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220

Query: 155  ---------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSA 205
                     S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A
Sbjct: 221  PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280

Query: 206  VSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------ 259
            +S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H+EDAGVICS      
Sbjct: 281  MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340

Query: 260  ----------------KGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303
                              + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V 
Sbjct: 341  TPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400

Query: 304  CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363
            C+QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV
Sbjct: 401  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460

Query: 364  TCSD--------------GSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADV 409
             CSD               S L LRL  GG RC G VEV  +   G VCD  W   +A+V
Sbjct: 461  ICSDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANV 520

Query: 410  VCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAK 469
            VCRQLGCG A+           +    L    C+GNE+ LW C +  W    C H E+A 
Sbjct: 521  VCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAG 580

Query: 470  ITCSAHREP---RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVS 526
            + CS        RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG   S
Sbjct: 581  VICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 640

Query: 527  ILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC----SRYT- 581
              G A FG+G+G I  ++ +C GHES+L  CP        C H  D GV+C    SR T 
Sbjct: 641  APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTP 700

Query: 582  ---------------------EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVL 620
                                  +RLVNG   C+GRVE+   G+WG++C+  WD  DA+V+
Sbjct: 701  RPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV 760

Query: 621  CQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASV 680
            C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     +  C   + A V
Sbjct: 761  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGV 820

Query: 681  ICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSW 740
            ICS +QS+   S ++          PE S         LRLVNGG RC GRVE+ + GSW
Sbjct: 821  ICSVSQSRPTPSPDTWPTSHASTAGPESSLA-------LRLVNGGDRCQGRVEVLYRGSW 873

Query: 741  GTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHS 800
            GT+CDDSWD SDA+VVCRQLGCG A +A G+A FG+G+GPI LD+++C+G ES +W C  
Sbjct: 874  GTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPH 933

Query: 801  HGWGQQNCRHKEDAGVICS--------------------------EFMSLRLTSEASREA 834
            +GW   NC+H EDAGVICS                            ++LRL +   R  
Sbjct: 934  NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDR-- 991

Query: 835  CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQ 894
            C GR+EV Y G+WGTV   S       VVCRQLGC         +     S P+ +D+V+
Sbjct: 992  CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR 1051

Query: 895  CPKGPDTLWQCPSSPW-----------------EKRLASPSEETWITCDNK--------- 928
            C      LW CP + W                  +   +PS +TW T             
Sbjct: 1052 CSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLA 1111

Query: 929  IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGT 988
            +RL  G   C GRVE+ + GSWGTVCDD WD +DA VVC+QLGCG A+ A   A FGQG+
Sbjct: 1112 LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1171

Query: 989  GPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKAT 1041
            GPI L++V+C G+ES LW CP   W    CGH EDA V C+    Q TP   T
Sbjct: 1172 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1224



 Score =  900 bits (2325), Expect = 0.0
 Identities = 488/1163 (41%), Positives = 629/1163 (54%), Gaps = 170/1163 (14%)

Query: 30   TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVIC 89
            T+ L  S     SSL      LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C
Sbjct: 468  TITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 522

Query: 90   NQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGV 149
             QLGC  A+ APG A    GSG I +D V C GNES LW C H+GW  H NC H +DAGV
Sbjct: 523  RQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSH-NCGHSEDAGV 581

Query: 150  TCSDG-SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208
             CS   S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++ + A+V+CRQL CG A S 
Sbjct: 582  ICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSA 641

Query: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261
             G++ FG+GSGPI  DD+ C+G+ES LW+C + GW  HNC H EDAGVICS         
Sbjct: 642  PGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPR 701

Query: 262  -----------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVAC 304
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C
Sbjct: 702  PDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 761

Query: 305  KQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVT 364
            +QLGC  A +A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAGV 
Sbjct: 762  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 821

Query: 365  CSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGW 402
            CS                        S L LRL  GG RC G VEV  +   G VCD  W
Sbjct: 822  CSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW 881

Query: 403  GLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS--CNGNETSLWDCKNWQWGGL 460
               +A+VVCRQLGCG A  TS    ++    +  + L    C+G E+ LW C +  W   
Sbjct: 882  DTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH 939

Query: 461  TCDHYEEAKITCSAHRE--------------------------PRLVGGDIPCSGRVEVK 494
             C H E+A + CSA                              RLV G   C GRVEV 
Sbjct: 940  NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVL 999

Query: 495  HGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHL 554
            +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES+L
Sbjct: 1000 YQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYL 1059

Query: 555  SLCPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IRLVNGKT 590
              CP        C HS D GV+CS                            +RLVNG  
Sbjct: 1060 WSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGD 1119

Query: 591  PCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMF 650
             C+GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A+S PG ARFG+G+G I     
Sbjct: 1120 RCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV 1179

Query: 651  HCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR--PTIPEE 708
             C+G E ++  CP     +  C   + A VICS +QSQ   S ++    PT    T   E
Sbjct: 1180 RCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT---WPTSHASTAGSE 1236

Query: 709  SAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINA 768
            S++A      LRLVNGG RC GRVE+ + GSWGT+CDD WD +DA+VVCRQLGCG A +A
Sbjct: 1237 SSLA------LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1290

Query: 769  TGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS----- 823
             G+A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS   S     
Sbjct: 1291 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1350

Query: 824  -------------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVC 864
                               LRL +   R  C GR+EV Y G+WGTV           VVC
Sbjct: 1351 PDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDYWDTNDANVVC 1408

Query: 865  RQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-------------- 910
            RQLGC         +     S P+ +D+V+C      LW CP + W              
Sbjct: 1409 RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 1468

Query: 911  ---EKRLASPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSW 958
                +   +PS +TW T             +RL  G   C GRVE+ + GSWGTVCDD W
Sbjct: 1469 CSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYW 1528

Query: 959  DLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSEC 1018
            D +DA VVC+QLGCG A+ A   A+FGQG+GPI L++V+C G+ES LW CP   W    C
Sbjct: 1529 DTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1588

Query: 1019 GHKEDAAVNCTDISVQKTPQKAT 1041
            GH EDA V C+    Q TP+  T
Sbjct: 1589 GHHEDAGVICSAAQSQSTPRPDT 1611



 Score =  899 bits (2324), Expect = 0.0
 Identities = 479/1131 (42%), Positives = 618/1131 (54%), Gaps = 151/1131 (13%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 234  LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS------------------ 152
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 294  GPIVLDDVRCSGHESYLWSCPHNGWLTH-NCGHSEDAGVICSAPQSRPTPSPDTWPTSHA 352

Query: 153  ----DGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++   A+V+CRQL CG A S 
Sbjct: 353  STAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 412

Query: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS--------- 259
             G++ FG+GSGPI  DD+ C+G ES LW+C H GW  HNC H+EDAGVICS         
Sbjct: 413  PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSDTLPTITLP 472

Query: 260  -----KGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVT 314
                   + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C+QLGC  A+ 
Sbjct: 473  ASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAML 532

Query: 315  AIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDG-SDLEL 373
            A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV CS   S L L
Sbjct: 533  APGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLAL 592

Query: 374  RLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQAT 433
            RL  GG RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS    ++    
Sbjct: 593  RLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA--TSAPGNARFGQG 650

Query: 434  NTWLFLSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP------------- 478
            +  + L    C+G+E+ LW C N  W    C H+E+A + CSA +               
Sbjct: 651  SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 710

Query: 479  -------------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVV 525
                         RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG   
Sbjct: 711  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 770

Query: 526  SILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS------- 578
            S  G A FG+G+G I  ++ +C GHES+L  CP        C H  D GV+CS       
Sbjct: 771  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 830

Query: 579  -----------------RYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLC 621
                                 +RLVNG   C+GRVE+   G+WG++C+  WD  DA+V+C
Sbjct: 831  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 890

Query: 622  QQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVI 681
            +QL CG A S PG ARFG+G+G I      C+G E ++  CP     +  C   + A VI
Sbjct: 891  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 950

Query: 682  CSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG-QLRLVNGGGRCAGRVEIYHEGSW 740
            CS   S +  S +      T PTI   ++    ES   LRLVNGG RC GRVE+ ++GSW
Sbjct: 951  CSAAHSWSTPSPD------TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSW 1004

Query: 741  GTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHS 800
            GT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G ES +W C  
Sbjct: 1005 GTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPH 1064

Query: 801  HGWGQQNCRHKEDAGVICS------------------------EFMSLRLTSEASREACA 836
            +GW   NC H EDAGVICS                          ++LRL +   R  C 
Sbjct: 1065 NGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQ 1122

Query: 837  GRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCP 896
            GR+EV Y G+WGTV           VVCRQLGC         +     S P+ +D+V+C 
Sbjct: 1123 GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 1182

Query: 897  KGPDTLWQCPSSPW-----------------EKRLASPSEETWITCDNK---------IR 930
                 LW CP + W                  +   +PS +TW T             +R
Sbjct: 1183 GHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALR 1242

Query: 931  LQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGP 990
            L  G   C GRVE+ + GSWGTVCDD WD +DA VVC+QLGCG A  A   A FGQG+GP
Sbjct: 1243 LVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGP 1302

Query: 991  IWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKAT 1041
            I L++V+C G+ES LW CP   W    CGH EDA V C+    Q TP   T
Sbjct: 1303 IVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1353



 Score =  886 bits (2290), Expect = 0.0
 Identities = 480/1174 (40%), Positives = 621/1174 (52%), Gaps = 190/1174 (16%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A  APG A    GS
Sbjct: 592  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 651

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154
            G I +D V C G+ES LW C ++GW  H NC H +DAGV CS                  
Sbjct: 652  GPIVLDDVRCSGHESYLWSCPNNGWLSH-NCGHHEDAGVICSAAQSRSTPRPDTLSTITL 710

Query: 155  --------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAV 206
                    S+L +RL  G + C GR+E+ ++G WGTVCDD+++ + A+V+CRQL CG A 
Sbjct: 711  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 770

Query: 207  SFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG----- 261
            S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS       
Sbjct: 771  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 830

Query: 262  -----------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVAC 304
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C
Sbjct: 831  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 890

Query: 305  KQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVT 364
            +QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV 
Sbjct: 891  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 950

Query: 365  CSDG------------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400
            CS                          S L LRL  GG RC G VEV  Q   G VCD 
Sbjct: 951  CSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD 1010

Query: 401  GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGL 460
             W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  W   
Sbjct: 1011 SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 1070

Query: 461  TCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVEVKHG 496
             C H E+A + CSA +                          RLV G   C GRVEV + 
Sbjct: 1071 NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYR 1130

Query: 497  DTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSL 556
             +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES+L  
Sbjct: 1131 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1190

Query: 557  CPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IRLVNGKTPC 592
            CP        C H  D GV+CS                            +RLVNG   C
Sbjct: 1191 CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1250

Query: 593  EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHC 652
            +GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A S PG ARFG+G+G I      C
Sbjct: 1251 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1310

Query: 653  TGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR--PTIPEESA 710
            +G E ++  CP     +  C   + A VICS +QSQ   S ++    PT    T   ES+
Sbjct: 1311 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT---WPTSHASTAGSESS 1367

Query: 711  VACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATG 770
            +A      LRLVNGG RC GRVE+ + GSWGT+CDD WD +DA+VVCRQLGCG A +A G
Sbjct: 1368 LA------LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPG 1421

Query: 771  SAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS------- 823
            +A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS   S       
Sbjct: 1422 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPD 1481

Query: 824  -----------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQ 866
                             LRL +   R  C GR+EV Y G+WGTV           VVCRQ
Sbjct: 1482 TWPTSRASTAGSESTLALRLVNGGDR--CRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 1539

Query: 867  LGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW---------------- 910
            LGC         +     S P+ +D+V+C      LW CP + W                
Sbjct: 1540 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1599

Query: 911  -EKRLASPSEETWITCDNK-----------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSW 958
              +  ++P  +TW+T +             +RL  G   C GRVE+ + GSWGTVCDDSW
Sbjct: 1600 AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 1659

Query: 959  DLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSEC 1018
            D +DA VVC+QLGCG A+ A   A FGQG+GPI L++V+C GNES LW CP + W    C
Sbjct: 1660 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1719

Query: 1019 GHKEDAAVNCTDISVQKT------PQKATTGRSS 1046
            GH EDA V C+   +  T      P   TT R S
Sbjct: 1720 GHHEDAGVICSATQINSTTTDWWHPTTTTTARPS 1753



 Score =  788 bits (2034), Expect = 0.0
 Identities = 422/1015 (41%), Positives = 554/1015 (54%), Gaps = 133/1015 (13%)

Query: 150  TCSDGSN--LEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVS 207
            T ++GS+  L +RL  G   C GR+EI ++G WGTVCDD+++ + A+V+CRQL CG A+S
Sbjct: 91   TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 150

Query: 208  FSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------ 261
              G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS        
Sbjct: 151  APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTL 210

Query: 262  -------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAV 302
                               + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V
Sbjct: 211  RPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV 270

Query: 303  ACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAG 362
             C+QLGC  A++A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAG
Sbjct: 271  VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAG 330

Query: 363  VTCS----------------------DGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400
            V CS                        S L LRL  GG RC G VEV  +   G VCD 
Sbjct: 331  VICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD 390

Query: 401  GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS--CNGNETSLWDCKNWQWG 458
             W   +A+VVCRQLGCG A  TS    ++    +  + L    C+G E+ LW C +  W 
Sbjct: 391  SWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448

Query: 459  GLTCDHYEEAKITCS----------------AHREPRLVGGDIPCSGRVEVKHGDTWGSI 502
               C H E+A + CS                +    RLV G   C GRVEV +  +WG++
Sbjct: 449  SHNCQHSEDAGVICSDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTV 508

Query: 503  CDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPR 562
            CD  +    A+V+CR+L CG  +   G A FG+G+G I  ++ +C G+ES+L  CP    
Sbjct: 509  CDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGW 568

Query: 563  PEGTCSHSRDVGVVCS---RYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHV 619
                C HS D GV+CS       +RLVNG   C+GRVE+   G+WG++C+  WD  DA+V
Sbjct: 569  LSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANV 628

Query: 620  LCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVAS 679
            +C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     +  C   + A 
Sbjct: 629  VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAG 688

Query: 680  VICSGNQSQTLSSCNSSSLGPTRP-TIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEG 738
            VICS  QS++    ++ S     P T+  ES++       LRLVNG  RC GRVE+ + G
Sbjct: 689  VICSAAQSRSTPRPDTLSTITLPPSTVGSESSLT------LRLVNGSDRCQGRVEVLYRG 742

Query: 739  SWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQC 798
            SWGT+CDDSWD +DA+VVCRQLGCG A +A G+A FG+G+GPI LD+++C+G ES +W C
Sbjct: 743  SWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSC 802

Query: 799  HSHGWGQQNCRHKEDAGVICS------------------------EFMSLRLTSEASREA 834
              +GW   NC H EDAGVICS                          ++LRL +   R  
Sbjct: 803  PHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDR-- 860

Query: 835  CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQ 894
            C GR+EV Y G+WGTV   S   +   VVCRQLGC         +     S P+ +D+V+
Sbjct: 861  CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVR 920

Query: 895  CPKGPDTLWQCPSSPWEKRLASPSEETWITCDN--------------------------- 927
            C      LW CP + W       SE+  + C                             
Sbjct: 921  CSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESS 980

Query: 928  -KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQ 986
              +RL  G   C GRVE+ + GSWGTVCDDSWD +DA VVC+QLGCG A+ A   A FGQ
Sbjct: 981  LALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQ 1040

Query: 987  GTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKAT 1041
            G+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    + TP   T
Sbjct: 1041 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT 1095



 Score =  622 bits (1604), Expect = e-178
 Identities = 349/885 (39%), Positives = 453/885 (51%), Gaps = 136/885 (15%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 1112 LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1171

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 1172 GPIVLDDVRCSGHESYLWSCPHNGWLSH-NCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1230

Query: 155  ------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A S 
Sbjct: 1231 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1290

Query: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261
             G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS         
Sbjct: 1291 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1350

Query: 262  ---------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQ 306
                           + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C+Q
Sbjct: 1351 PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 1410

Query: 307  LGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS 366
            LGC  A +A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAGV CS
Sbjct: 1411 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1470

Query: 367  DG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGL 404
                                    S L LRL  GG RC G VEV  Q   G VCD  W  
Sbjct: 1471 ASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT 1530

Query: 405  KEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDH 464
             +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  W    C H
Sbjct: 1531 NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1590

Query: 465  YEEAKITCSAHREP--------------------------RLVGGDIPCSGRVEVKHGDT 498
            +E+A + CSA +                            RLV G   C GRVEV +  +
Sbjct: 1591 HEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGS 1650

Query: 499  WGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCP 558
            WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C G+ES+L  CP
Sbjct: 1651 WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP 1710

Query: 559  VAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAH 618
                    C H  D GV+CS       +N  T         T     S C          
Sbjct: 1711 HKGWLTHNCGHHEDAGVICSATQ----INSTTTDWWHPTTTTTARPSSNCGGFLFYASGT 1766

Query: 619  VLC--------QQLKCGVALSTPGGARFGKGNGQIWRHMFH-CTGTEQHMGDCPVTALGA 669
                          KC   +    G R   G   +     H C+     + D    +L +
Sbjct: 1767 FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFD---GSLNS 1823

Query: 670  SLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG------------ 717
            SL     +   IC+  +    SS N       R TI   S ++   +G            
Sbjct: 1824 SL-----LLGKICNDTRQIFTSSYN-------RMTIHFRSDISFQNTGFLAWYNSFPSDA 1871

Query: 718  QLRLVN---GGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHF 774
             LRLVN     G CAGRVEIYH G+WGT+CDDSW + +A VVCRQLGCG A++A G+A+F
Sbjct: 1872 TLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF 1931

Query: 775  GEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
            G G+GPI LD+++C+G ES +WQC + GW   NC H+EDAGVICS
Sbjct: 1932 GSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1976



 Score =  621 bits (1602), Expect = e-177
 Identities = 376/1048 (35%), Positives = 512/1048 (48%), Gaps = 180/1048 (17%)

Query: 25   SPFTI-TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSME 83
            SP T+ T+ L  S     SSL      LRLV+G ++C GRVEV  Q  WGTVC++ W   
Sbjct: 961  SPDTLPTITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 1015

Query: 84   AVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143
              +V+C QLGC  A+ APG A    GSG I +D V C G+ES LW C H+GW  H NC H
Sbjct: 1016 DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH-NCGH 1074

Query: 144  QQDAGVTCSDG----------------------SNLEMRLTRGGNMCSGRIEIKFQGRWG 181
             +DAGV CS                        S+L +RL  GG+ C GR+E+ ++G WG
Sbjct: 1075 SEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWG 1134

Query: 182  TVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQ 241
            TVCDD ++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H 
Sbjct: 1135 TVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHN 1194

Query: 242  GWGKHNCDHAEDAGVICSKG----------------------ADLSLRLVDGVTECSGRL 279
            GW  HNC H EDAGVICS                        + L+LRLV+G   C GR+
Sbjct: 1195 GWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRV 1254

Query: 280  EVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHE 339
            EV ++G WGT+CDD WD+ DA V C+QLGC  A +A G     +G G I LD V C GHE
Sbjct: 1255 EVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 1314

Query: 340  PAVWQCKHHEWGKHYCNHNEDAGVTCSDG----------------------SDLELRLRG 377
              +W C H+ W  H C H+EDAGV CS                        S L LRL  
Sbjct: 1315 SYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVN 1374

Query: 378  GGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWL 437
            GG RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS    ++    +  +
Sbjct: 1375 GGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA--TSAPGNARFGQGSGPI 1432

Query: 438  FLSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP----------------- 478
             L    C+G+E+ LW C +  W    C H+E+A + CSA +                   
Sbjct: 1433 VLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAG 1492

Query: 479  -------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGA 531
                   RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG  +S  G A
Sbjct: 1493 SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA 1552

Query: 532  HFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE--------- 582
             FG+G+G I  ++ +C GHES+L  CP        C H  D GV+CS             
Sbjct: 1553 QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW 1612

Query: 583  -----------------IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLK 625
                             +RLVNG   C GRVE+   G+WG++C+  WD  DA+V+C+QL 
Sbjct: 1613 LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 1672

Query: 626  CGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGN 685
            CG A+S PG ARFG+G+G I      C+G E ++  CP        C   + A VICS  
Sbjct: 1673 CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT 1732

Query: 686  QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICD 745
            Q   ++S  +    PT  T    S+                 C G +  Y  G++ +   
Sbjct: 1733 Q---INSTTTDWWHPTTTTTARPSS----------------NCGGFL-FYASGTFSSPSY 1772

Query: 746  DSWDLSDAHVVCR-QLGCGEAINATGS-----AHF-----------GEGTGPIWLDEMKC 788
             ++  ++A  V   ++  G  IN   S     AH            G     + L ++ C
Sbjct: 1773 PAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI-C 1831

Query: 789  NGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS----------LRLTS-EASREACAG 837
            N       Q  +  + +     + D     + F++          LRL +  +S   CAG
Sbjct: 1832 NDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAG 1887

Query: 838  RLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPK 897
            R+E+++ G WGTV   S +     VVCRQLGC         +   + S P+ +D+V+C  
Sbjct: 1888 RVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSG 1947

Query: 898  GPDTLWQCPSSPWEKRLASPSEETWITC 925
               TLWQC +  W     +  E+  + C
Sbjct: 1948 TESTLWQCRNRGWFSHNCNHREDAGVIC 1975



 Score =  322 bits (826), Expect = 1e-87
 Identities = 180/441 (40%), Positives = 227/441 (51%), Gaps = 59/441 (13%)

Query: 663  PVTALGASLCPSEQVASVICSGN----QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQ 718
            P  A G+       + S +  G+    +S   S+    SL P+  T+    A        
Sbjct: 42   PTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLA 101

Query: 719  LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGT 778
            LRLVNG GRC GRVEI + GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+
Sbjct: 102  LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161

Query: 779  GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS------------------- 819
            GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS                   
Sbjct: 162  GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221

Query: 820  --------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCAD 871
                      ++LRL +   R  C GR+EV Y G+WGTV           VVCRQLGC  
Sbjct: 222  PVPTEGSESSLALRLVNGGDR--CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279

Query: 872  KGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRL 914
                   +     S P+ +D+V+C      LW CP + W                  +  
Sbjct: 280  AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339

Query: 915  ASPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQV 965
             +PS +TW T             +RL  G   C GRVE+ + GSWGTVCDDSWD  DA V
Sbjct: 340  PTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANV 399

Query: 966  VCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAA 1025
            VC+QLGCG A  A   A FGQG+GPI L++V+C G ES LW CP   W    C H EDA 
Sbjct: 400  VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAG 459

Query: 1026 VNCTDISVQKTPQKATTGRSS 1046
            V C+D     T   +T G  S
Sbjct: 460  VICSDTLPTITLPASTVGSES 480



 Score =  130 bits (328), Expect = 5e-30
 Identities = 54/92 (58%), Positives = 69/92 (75%)

Query: 938  CSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVK 997
            C+GRVEI+HGG+WGTVCDDSW + +A+VVC+QLGCG A+ A   A FG G+GPI L++V+
Sbjct: 1885 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1944

Query: 998  CKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029
            C G ES+LW C  R W    C H+EDA V C+
Sbjct: 1945 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1976



 Score =  108 bits (271), Expect = 2e-23
 Identities = 51/109 (46%), Positives = 69/109 (63%), Gaps = 4/109 (3%)

Query: 47   TDKELRLVDGENK---CSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGW 103
            +D  LRLV+  +    C+GRVE+     WGTVC++ W+++   V+C QLGC  A+ A G 
Sbjct: 1869 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1928

Query: 104  ANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152
            A   +GSG I +D V C G ES LW C++ GW  H NC H++DAGV CS
Sbjct: 1929 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSH-NCNHREDAGVICS 1976



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%)

Query: 583  IRLVNGKTP---CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
            +RLVN  +    C GRVE+   G WG++C+  W I++A V+C+QL CG A+S  G A FG
Sbjct: 1873 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1932

Query: 640  KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
             G+G I      C+GTE  +  C      +  C   + A VICSGN   T
Sbjct: 1933 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1982



 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 44/110 (40%), Positives = 58/110 (52%), Gaps = 3/110 (2%)

Query: 369  SDLELRLRGGGSR---CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQ 425
            SD  LRL    S    CAG VE+      G VCD  W ++EA+VVCRQLGCG A+     
Sbjct: 1869 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1928

Query: 426  VYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAH 475
             Y    +    L    C+G E++LW C+N  W    C+H E+A + CS +
Sbjct: 1929 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1978


>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
            [Homo sapiens]
          Length = 2413

 Score =  901 bits (2328), Expect = 0.0
 Identities = 491/1169 (42%), Positives = 633/1169 (54%), Gaps = 171/1169 (14%)

Query: 25   SPFTI-TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSME 83
            SP T+ T+ L  S     SSL      LRLV+G ++C GRVEV  +  WGTVC++ W   
Sbjct: 472  SPDTLPTITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 526

Query: 84   AVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143
              +V+C QLGC  A+ APG A    GSG I +D V C GNES LW C H+GW  H NC H
Sbjct: 527  DANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSH-NCGH 585

Query: 144  QQDAGVTCSDG-SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLEC 202
             +DAGV CS   S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++ + A+V+CRQL C
Sbjct: 586  SEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 645

Query: 203  GSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG- 261
            G A S  G++ FG+GSGPI  DD+ C+G+ES LW+C + GW  HNC H EDAGVICS   
Sbjct: 646  GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQ 705

Query: 262  -----------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSY 298
                                   + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ 
Sbjct: 706  SRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTN 765

Query: 299  DAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHN 358
            DA V C+QLGC  A +A G     +G G I LD V C GHE  +W C H+ W  H C H+
Sbjct: 766  DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHH 825

Query: 359  EDAGVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGK 396
            EDAGV CS                        S L LRL  GG RC G VEV  +   G 
Sbjct: 826  EDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGT 885

Query: 397  VCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS--CNGNETSLWDCKN 454
            VCD  W   +A+VVCRQLGCG A  TS    ++    +  + L    C+G E+ LW C +
Sbjct: 886  VCDDSWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPH 943

Query: 455  WQWGGLTCDHYEEAKITCSAHRE--------------------------PRLVGGDIPCS 488
              W    C H E+A + CSA                              RLV G   C 
Sbjct: 944  NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ 1003

Query: 489  GRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCE 548
            GRVEV +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C 
Sbjct: 1004 GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 1063

Query: 549  GHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IR 584
            GHES+L  CP        C HS D GV+CS                            +R
Sbjct: 1064 GHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALR 1123

Query: 585  LVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQ 644
            LVNG   C+GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A+S PG ARFG+G+G 
Sbjct: 1124 LVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGP 1183

Query: 645  IWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR-- 702
            I      C+G E ++  CP     +  C   + A VICS +QSQ   S ++    PT   
Sbjct: 1184 IVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT---WPTSHA 1240

Query: 703  PTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGC 762
             T   ES++A      LRLVNGG RC GRVE+ + GSWGT+CDD WD +DA+VVCRQLGC
Sbjct: 1241 STAGSESSLA------LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1294

Query: 763  GEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFM 822
            G A +A G+A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS   
Sbjct: 1295 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1354

Query: 823  S------------------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSET 858
            S                        LRL +   R  C GR+EV Y G+WGTV        
Sbjct: 1355 SQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDYWDTN 1412

Query: 859  TVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-------- 910
               VVCRQLGC         +     S P+ +D+V+C      LW CP + W        
Sbjct: 1413 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHH 1472

Query: 911  ---------EKRLASPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGT 952
                      +   +PS +TW T             +RL  G   C GRVE+ + GSWGT
Sbjct: 1473 EDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGT 1532

Query: 953  VCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARR 1012
            VCDD WD +DA VVC+QLGCG A+ A   A+FGQG+GPI L++V+C G+ES LW CP   
Sbjct: 1533 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNG 1592

Query: 1013 WGHSECGHKEDAAVNCTDISVQKTPQKAT 1041
            W    CGH EDA V C+    Q TP+  T
Sbjct: 1593 WLSHNCGHHEDAGVICSAAQSQSTPRPDT 1621



 Score =  896 bits (2315), Expect = 0.0
 Identities = 477/1143 (41%), Positives = 614/1143 (53%), Gaps = 162/1143 (14%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G+ +C GRVE+  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 102  LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 162  GPIALDDVRCSGHESYLWSCPHNGWLSH-NCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220

Query: 155  ---------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSA 205
                     S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A
Sbjct: 221  PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280

Query: 206  VSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------ 259
            +S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H+EDAGVICS      
Sbjct: 281  MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340

Query: 260  ----------------KGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303
                              + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V 
Sbjct: 341  TPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400

Query: 304  CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363
            C+QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV
Sbjct: 401  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460

Query: 364  TCS------------------------DGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCD 399
             CS                          S L LRL  GG RC G VEV  +   G VCD
Sbjct: 461  ICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 520

Query: 400  RGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGG 459
              W   +A+VVCRQLGCG A+           +    L    C+GNE+ LW C +  W  
Sbjct: 521  DSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLS 580

Query: 460  LTCDHYEEAKITCSAHREP---RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLC 516
              C H E+A + CS        RLV G   C GRVEV +  +WG++CD  +    A+V+C
Sbjct: 581  HNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 640

Query: 517  RELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVV 576
            R+L CG   S  G A FG+G+G I  ++ +C GHES+L  CP        C H  D GV+
Sbjct: 641  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVI 700

Query: 577  C----SRYT----------------------EIRLVNGKTPCEGRVELKTLGAWGSLCNS 610
            C    SR T                       +RLVNG   C+GRVE+   G+WG++C+ 
Sbjct: 701  CSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDD 760

Query: 611  HWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGAS 670
             WD  DA+V+C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     + 
Sbjct: 761  SWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 820

Query: 671  LCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAG 730
             C   + A VICS +QS+   S ++          PE S         LRLVNGG RC G
Sbjct: 821  NCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLA-------LRLVNGGDRCQG 873

Query: 731  RVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790
            RVE+ + GSWGT+CDDSWD SDA+VVCRQLGCG A +A G+A FG+G+GPI LD+++C+G
Sbjct: 874  RVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSG 933

Query: 791  KESRIWQCHSHGWGQQNCRHKEDAGVICS--------------------------EFMSL 824
             ES +W C  +GW   NC+H EDAGVICS                            ++L
Sbjct: 934  YESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLAL 993

Query: 825  RLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAM 884
            RL +   R  C GR+EV Y G+WGTV   S       VVCRQLGC         +     
Sbjct: 994  RLVNGGDR--CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1051

Query: 885  SIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRLASPSEETWITCDN 927
            S P+ +D+V+C      LW CP + W                  +   +PS +TW T   
Sbjct: 1052 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHA 1111

Query: 928  K---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKA 978
                      +RL  G   C GRVE+ + GSWGTVCDD WD +DA VVC+QLGCG A+ A
Sbjct: 1112 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1171

Query: 979  FKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQ 1038
               A FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    Q TP 
Sbjct: 1172 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1231

Query: 1039 KAT 1041
              T
Sbjct: 1232 PDT 1234



 Score =  896 bits (2315), Expect = 0.0
 Identities = 479/1141 (41%), Positives = 618/1141 (54%), Gaps = 161/1141 (14%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 234  LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS------------------ 152
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 294  GPIVLDDVRCSGHESYLWSCPHNGWLTH-NCGHSEDAGVICSAPQSRPTPSPDTWPTSHA 352

Query: 153  ----DGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++   A+V+CRQL CG A S 
Sbjct: 353  STAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 412

Query: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261
             G++ FG+GSGPI  DD+ C+G ES LW+C H GW  HNC H+EDAGVICS         
Sbjct: 413  PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPS 472

Query: 262  -----------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVAC 304
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C
Sbjct: 473  PDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 532

Query: 305  KQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVT 364
            +QLGC  A+ A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV 
Sbjct: 533  RQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVI 592

Query: 365  CSDG-SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTS 423
            CS   S L LRL  GG RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS
Sbjct: 593  CSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA--TS 650

Query: 424  YQVYSKIQATNTWLFLSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP--- 478
                ++    +  + L    C+G+E+ LW C N  W    C H+E+A + CSA +     
Sbjct: 651  APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTP 710

Query: 479  -----------------------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVL 515
                                   RLV G   C GRVEV +  +WG++CD  +    A+V+
Sbjct: 711  RPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV 770

Query: 516  CRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGV 575
            CR+L CG   S  G A FG+G+G I  ++ +C GHES+L  CP        C H  D GV
Sbjct: 771  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGV 830

Query: 576  VCS------------------------RYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSH 611
            +CS                            +RLVNG   C+GRVE+   G+WG++C+  
Sbjct: 831  ICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 890

Query: 612  WDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASL 671
            WD  DA+V+C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     +  
Sbjct: 891  WDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN 950

Query: 672  CPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG-QLRLVNGGGRCAG 730
            C   + A VICS   S +  S +      T PTI   ++    ES   LRLVNGG RC G
Sbjct: 951  CQHSEDAGVICSAAHSWSTPSPD------TLPTITLPASTVGSESSLALRLVNGGDRCQG 1004

Query: 731  RVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790
            RVE+ ++GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G
Sbjct: 1005 RVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1064

Query: 791  KESRIWQCHSHGWGQQNCRHKEDAGVICS------------------------EFMSLRL 826
             ES +W C  +GW   NC H EDAGVICS                          ++LRL
Sbjct: 1065 HESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRL 1124

Query: 827  TSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSI 886
             +   R  C GR+EV Y G+WGTV           VVCRQLGC         +     S 
Sbjct: 1125 VNGGDR--CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSG 1182

Query: 887  PMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRLASPSEETWITCDNK- 928
            P+ +D+V+C      LW CP + W                  +   +PS +TW T     
Sbjct: 1183 PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHAST 1242

Query: 929  --------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFK 980
                    +RL  G   C GRVE+ + GSWGTVCDD WD +DA VVC+QLGCG A  A  
Sbjct: 1243 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPG 1302

Query: 981  EAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKA 1040
             A FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    Q TP   
Sbjct: 1303 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPD 1362

Query: 1041 T 1041
            T
Sbjct: 1363 T 1363



 Score =  886 bits (2290), Expect = 0.0
 Identities = 480/1174 (40%), Positives = 621/1174 (52%), Gaps = 190/1174 (16%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A  APG A    GS
Sbjct: 602  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 661

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154
            G I +D V C G+ES LW C ++GW  H NC H +DAGV CS                  
Sbjct: 662  GPIVLDDVRCSGHESYLWSCPNNGWLSH-NCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720

Query: 155  --------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAV 206
                    S+L +RL  G + C GR+E+ ++G WGTVCDD+++ + A+V+CRQL CG A 
Sbjct: 721  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780

Query: 207  SFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG----- 261
            S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS       
Sbjct: 781  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 840

Query: 262  -----------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVAC 304
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C
Sbjct: 841  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 900

Query: 305  KQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVT 364
            +QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV 
Sbjct: 901  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 960

Query: 365  CSDG------------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400
            CS                          S L LRL  GG RC G VEV  Q   G VCD 
Sbjct: 961  CSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD 1020

Query: 401  GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGL 460
             W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  W   
Sbjct: 1021 SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 1080

Query: 461  TCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVEVKHG 496
             C H E+A + CSA +                          RLV G   C GRVEV + 
Sbjct: 1081 NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYR 1140

Query: 497  DTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSL 556
             +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES+L  
Sbjct: 1141 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1200

Query: 557  CPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IRLVNGKTPC 592
            CP        C H  D GV+CS                            +RLVNG   C
Sbjct: 1201 CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1260

Query: 593  EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHC 652
            +GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A S PG ARFG+G+G I      C
Sbjct: 1261 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1320

Query: 653  TGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR--PTIPEESA 710
            +G E ++  CP     +  C   + A VICS +QSQ   S ++    PT    T   ES+
Sbjct: 1321 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT---WPTSHASTAGSESS 1377

Query: 711  VACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATG 770
            +A      LRLVNGG RC GRVE+ + GSWGT+CDD WD +DA+VVCRQLGCG A +A G
Sbjct: 1378 LA------LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPG 1431

Query: 771  SAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS------- 823
            +A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS   S       
Sbjct: 1432 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPD 1491

Query: 824  -----------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQ 866
                             LRL +   R  C GR+EV Y G+WGTV           VVCRQ
Sbjct: 1492 TWPTSRASTAGSESTLALRLVNGGDR--CRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 1549

Query: 867  LGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW---------------- 910
            LGC         +     S P+ +D+V+C      LW CP + W                
Sbjct: 1550 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1609

Query: 911  -EKRLASPSEETWITCDNK-----------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSW 958
              +  ++P  +TW+T +             +RL  G   C GRVE+ + GSWGTVCDDSW
Sbjct: 1610 AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 1669

Query: 959  DLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSEC 1018
            D +DA VVC+QLGCG A+ A   A FGQG+GPI L++V+C GNES LW CP + W    C
Sbjct: 1670 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1729

Query: 1019 GHKEDAAVNCTDISVQKT------PQKATTGRSS 1046
            GH EDA V C+   +  T      P   TT R S
Sbjct: 1730 GHHEDAGVICSATQINSTTTDWWHPTTTTTARPS 1763



 Score =  786 bits (2029), Expect = 0.0
 Identities = 423/1025 (41%), Positives = 554/1025 (54%), Gaps = 143/1025 (13%)

Query: 150  TCSDGSN--LEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVS 207
            T ++GS+  L +RL  G   C GR+EI ++G WGTVCDD+++ + A+V+CRQL CG A+S
Sbjct: 91   TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 150

Query: 208  FSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------ 261
              G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS        
Sbjct: 151  APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTL 210

Query: 262  -------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAV 302
                               + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V
Sbjct: 211  RPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV 270

Query: 303  ACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAG 362
             C+QLGC  A++A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAG
Sbjct: 271  VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAG 330

Query: 363  VTCS----------------------DGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400
            V CS                        S L LRL  GG RC G VEV  +   G VCD 
Sbjct: 331  VICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD 390

Query: 401  GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS--CNGNETSLWDCKNWQWG 458
             W   +A+VVCRQLGCG A  TS    ++    +  + L    C+G E+ LW C +  W 
Sbjct: 391  SWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448

Query: 459  GLTCDHYEEAKITCSAHRE--------------------------PRLVGGDIPCSGRVE 492
               C H E+A + CSA                              RLV G   C GRVE
Sbjct: 449  SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508

Query: 493  VKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHES 552
            V +  +WG++CD  +    A+V+CR+L CG  +   G A FG+G+G I  ++ +C G+ES
Sbjct: 509  VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNES 568

Query: 553  HLSLCPVAPRPEGTCSHSRDVGVVCS---RYTEIRLVNGKTPCEGRVELKTLGAWGSLCN 609
            +L  CP        C HS D GV+CS       +RLVNG   C+GRVE+   G+WG++C+
Sbjct: 569  YLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 628

Query: 610  SHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGA 669
              WD  DA+V+C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     +
Sbjct: 629  DSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLS 688

Query: 670  SLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRP-TIPEESAVACIESGQLRLVNGGGRC 728
              C   + A VICS  QS++    ++ S     P T+  ES++       LRLVNG  RC
Sbjct: 689  HNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLT------LRLVNGSDRC 742

Query: 729  AGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKC 788
             GRVE+ + GSWGT+CDDSWD +DA+VVCRQLGCG A +A G+A FG+G+GPI LD+++C
Sbjct: 743  QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 802

Query: 789  NGKESRIWQCHSHGWGQQNCRHKEDAGVICS------------------------EFMSL 824
            +G ES +W C  +GW   NC H EDAGVICS                          ++L
Sbjct: 803  SGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLAL 862

Query: 825  RLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAM 884
            RL +   R  C GR+EV Y G+WGTV   S   +   VVCRQLGC         +     
Sbjct: 863  RLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 920

Query: 885  SIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN----------------- 927
            S P+ +D+V+C      LW CP + W       SE+  + C                   
Sbjct: 921  SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 980

Query: 928  -----------KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPAL 976
                        +RL  G   C GRVE+ + GSWGTVCDDSWD +DA VVC+QLGCG A+
Sbjct: 981  PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1040

Query: 977  KAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKT 1036
             A   A FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    + T
Sbjct: 1041 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1100

Query: 1037 PQKAT 1041
            P   T
Sbjct: 1101 PSPDT 1105



 Score =  622 bits (1604), Expect = e-178
 Identities = 349/885 (39%), Positives = 453/885 (51%), Gaps = 136/885 (15%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 1122 LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1181

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 1182 GPIVLDDVRCSGHESYLWSCPHNGWLSH-NCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1240

Query: 155  ------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A S 
Sbjct: 1241 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1300

Query: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261
             G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS         
Sbjct: 1301 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1360

Query: 262  ---------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQ 306
                           + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C+Q
Sbjct: 1361 PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 1420

Query: 307  LGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS 366
            LGC  A +A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAGV CS
Sbjct: 1421 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1480

Query: 367  DG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGL 404
                                    S L LRL  GG RC G VEV  Q   G VCD  W  
Sbjct: 1481 ASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT 1540

Query: 405  KEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDH 464
             +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  W    C H
Sbjct: 1541 NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1600

Query: 465  YEEAKITCSAHREP--------------------------RLVGGDIPCSGRVEVKHGDT 498
            +E+A + CSA +                            RLV G   C GRVEV +  +
Sbjct: 1601 HEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGS 1660

Query: 499  WGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCP 558
            WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C G+ES+L  CP
Sbjct: 1661 WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP 1720

Query: 559  VAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAH 618
                    C H  D GV+CS       +N  T         T     S C          
Sbjct: 1721 HKGWLTHNCGHHEDAGVICSATQ----INSTTTDWWHPTTTTTARPSSNCGGFLFYASGT 1776

Query: 619  VLC--------QQLKCGVALSTPGGARFGKGNGQIWRHMFH-CTGTEQHMGDCPVTALGA 669
                          KC   +    G R   G   +     H C+     + D    +L +
Sbjct: 1777 FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFD---GSLNS 1833

Query: 670  SLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG------------ 717
            SL     +   IC+  +    SS N       R TI   S ++   +G            
Sbjct: 1834 SL-----LLGKICNDTRQIFTSSYN-------RMTIHFRSDISFQNTGFLAWYNSFPSDA 1881

Query: 718  QLRLVN---GGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHF 774
             LRLVN     G CAGRVEIYH G+WGT+CDDSW + +A VVCRQLGCG A++A G+A+F
Sbjct: 1882 TLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF 1941

Query: 775  GEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
            G G+GPI LD+++C+G ES +WQC + GW   NC H+EDAGVICS
Sbjct: 1942 GSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986



 Score =  621 bits (1602), Expect = e-177
 Identities = 376/1048 (35%), Positives = 512/1048 (48%), Gaps = 180/1048 (17%)

Query: 25   SPFTI-TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSME 83
            SP T+ T+ L  S     SSL      LRLV+G ++C GRVEV  Q  WGTVC++ W   
Sbjct: 971  SPDTLPTITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 1025

Query: 84   AVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143
              +V+C QLGC  A+ APG A    GSG I +D V C G+ES LW C H+GW  H NC H
Sbjct: 1026 DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH-NCGH 1084

Query: 144  QQDAGVTCSDG----------------------SNLEMRLTRGGNMCSGRIEIKFQGRWG 181
             +DAGV CS                        S+L +RL  GG+ C GR+E+ ++G WG
Sbjct: 1085 SEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWG 1144

Query: 182  TVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQ 241
            TVCDD ++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H 
Sbjct: 1145 TVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHN 1204

Query: 242  GWGKHNCDHAEDAGVICSKG----------------------ADLSLRLVDGVTECSGRL 279
            GW  HNC H EDAGVICS                        + L+LRLV+G   C GR+
Sbjct: 1205 GWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRV 1264

Query: 280  EVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHE 339
            EV ++G WGT+CDD WD+ DA V C+QLGC  A +A G     +G G I LD V C GHE
Sbjct: 1265 EVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 1324

Query: 340  PAVWQCKHHEWGKHYCNHNEDAGVTCSDG----------------------SDLELRLRG 377
              +W C H+ W  H C H+EDAGV CS                        S L LRL  
Sbjct: 1325 SYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVN 1384

Query: 378  GGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWL 437
            GG RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS    ++    +  +
Sbjct: 1385 GGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA--TSAPGNARFGQGSGPI 1442

Query: 438  FLSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP----------------- 478
             L    C+G+E+ LW C +  W    C H+E+A + CSA +                   
Sbjct: 1443 VLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAG 1502

Query: 479  -------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGA 531
                   RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG  +S  G A
Sbjct: 1503 SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA 1562

Query: 532  HFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE--------- 582
             FG+G+G I  ++ +C GHES+L  CP        C H  D GV+CS             
Sbjct: 1563 QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW 1622

Query: 583  -----------------IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLK 625
                             +RLVNG   C GRVE+   G+WG++C+  WD  DA+V+C+QL 
Sbjct: 1623 LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 1682

Query: 626  CGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGN 685
            CG A+S PG ARFG+G+G I      C+G E ++  CP        C   + A VICS  
Sbjct: 1683 CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT 1742

Query: 686  QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICD 745
            Q   ++S  +    PT  T    S+                 C G +  Y  G++ +   
Sbjct: 1743 Q---INSTTTDWWHPTTTTTARPSS----------------NCGGFL-FYASGTFSSPSY 1782

Query: 746  DSWDLSDAHVVCR-QLGCGEAINATGS-----AHF-----------GEGTGPIWLDEMKC 788
             ++  ++A  V   ++  G  IN   S     AH            G     + L ++ C
Sbjct: 1783 PAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI-C 1841

Query: 789  NGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS----------LRLTS-EASREACAG 837
            N       Q  +  + +     + D     + F++          LRL +  +S   CAG
Sbjct: 1842 NDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAG 1897

Query: 838  RLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPK 897
            R+E+++ G WGTV   S +     VVCRQLGC         +   + S P+ +D+V+C  
Sbjct: 1898 RVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSG 1957

Query: 898  GPDTLWQCPSSPWEKRLASPSEETWITC 925
               TLWQC +  W     +  E+  + C
Sbjct: 1958 TESTLWQCRNRGWFSHNCNHREDAGVIC 1985



 Score =  414 bits (1064), Expect = e-115
 Identities = 223/529 (42%), Positives = 288/529 (54%), Gaps = 68/529 (12%)

Query: 555  SLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDI 614
            SL P     E T +   D G+       +RLVNG   C+GRVE+   G+WG++C+  WD 
Sbjct: 80   SLIPSESTLESTVAEGSDSGLA------LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDT 133

Query: 615  EDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPS 674
             DA+V+C+QL CG A+S PG A FG+G+G I      C+G E ++  CP     +  C  
Sbjct: 134  NDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGH 193

Query: 675  EQVASVICSGNQSQTLSSCNS--SSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRV 732
             + A VICS  Q Q+     S    + P  PT   ES++A      LRLVNGG RC GRV
Sbjct: 194  GEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLA------LRLVNGGDRCRGRV 247

Query: 733  EIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKE 792
            E+ + GSWGT+CDD WD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G E
Sbjct: 248  EVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHE 307

Query: 793  SRIWQCHSHGWGQQNCRHKEDAGVICS------------------------EFMSLRLTS 828
            S +W C  +GW   NC H EDAGVICS                          ++LRL +
Sbjct: 308  SYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVN 367

Query: 829  EASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPM 888
               R  C GR+EV Y G+WGTV   S   +   VVCRQLGC         +     S P+
Sbjct: 368  GGDR--CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPI 425

Query: 889  WVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN--------------------- 927
             +D+V+C      LW CP + W       SE+  + C                       
Sbjct: 426  VLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPAST 485

Query: 928  -------KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFK 980
                    +RL  G   C GRVE+ + GSWGTVCDDSWD +DA VVC+QLGCG A+ A  
Sbjct: 486  VGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPG 545

Query: 981  EAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029
             A FGQG+GPI L++V+C GNES LW CP   W    CGH EDA V C+
Sbjct: 546  NARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594



 Score =  320 bits (820), Expect = 5e-87
 Identities = 178/436 (40%), Positives = 224/436 (51%), Gaps = 59/436 (13%)

Query: 663  PVTALGASLCPSEQVASVICSGN----QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQ 718
            P  A G+       + S +  G+    +S   S+    SL P+  T+    A        
Sbjct: 42   PTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLA 101

Query: 719  LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGT 778
            LRLVNG GRC GRVEI + GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+
Sbjct: 102  LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161

Query: 779  GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS------------------- 819
            GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS                   
Sbjct: 162  GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221

Query: 820  --------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCAD 871
                      ++LRL +   R  C GR+EV Y G+WGTV           VVCRQLGC  
Sbjct: 222  PVPTEGSESSLALRLVNGGDR--CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279

Query: 872  KGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRL 914
                   +     S P+ +D+V+C      LW CP + W                  +  
Sbjct: 280  AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339

Query: 915  ASPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQV 965
             +PS +TW T             +RL  G   C GRVE+ + GSWGTVCDDSWD  DA V
Sbjct: 340  PTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANV 399

Query: 966  VCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAA 1025
            VC+QLGCG A  A   A FGQG+GPI L++V+C G ES LW CP   W    C H EDA 
Sbjct: 400  VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAG 459

Query: 1026 VNCTDISVQKTPQKAT 1041
            V C+      TP   T
Sbjct: 460  VICSAAHSWSTPSPDT 475



 Score =  130 bits (328), Expect = 5e-30
 Identities = 54/92 (58%), Positives = 69/92 (75%)

Query: 938  CSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVK 997
            C+GRVEI+HGG+WGTVCDDSW + +A+VVC+QLGCG A+ A   A FG G+GPI L++V+
Sbjct: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1954

Query: 998  CKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029
            C G ES+LW C  R W    C H+EDA V C+
Sbjct: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986



 Score =  108 bits (271), Expect = 2e-23
 Identities = 51/109 (46%), Positives = 69/109 (63%), Gaps = 4/109 (3%)

Query: 47   TDKELRLVDGENK---CSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGW 103
            +D  LRLV+  +    C+GRVE+     WGTVC++ W+++   V+C QLGC  A+ A G 
Sbjct: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1938

Query: 104  ANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152
            A   +GSG I +D V C G ES LW C++ GW  H NC H++DAGV CS
Sbjct: 1939 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSH-NCNHREDAGVICS 1986



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%)

Query: 583  IRLVNGKTP---CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
            +RLVN  +    C GRVE+   G WG++C+  W I++A V+C+QL CG A+S  G A FG
Sbjct: 1883 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1942

Query: 640  KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
             G+G I      C+GTE  +  C      +  C   + A VICSGN   T
Sbjct: 1943 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1992



 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 44/110 (40%), Positives = 58/110 (52%), Gaps = 3/110 (2%)

Query: 369  SDLELRLRGGGSR---CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQ 425
            SD  LRL    S    CAG VE+      G VCD  W ++EA+VVCRQLGCG A+     
Sbjct: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1938

Query: 426  VYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAH 475
             Y    +    L    C+G E++LW C+N  W    C+H E+A + CS +
Sbjct: 1939 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1988


>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
            [Homo sapiens]
          Length = 1785

 Score =  788 bits (2036), Expect = 0.0
 Identities = 433/1058 (40%), Positives = 564/1058 (53%), Gaps = 174/1058 (16%)

Query: 150  TCSDGSN--LEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVS 207
            T ++GS+  L +RL  G   C GR+EI ++G WGTVCDD+++ + A+V+CRQL CG A+S
Sbjct: 91   TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 150

Query: 208  FSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------ 261
              G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS        
Sbjct: 151  APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTL 210

Query: 262  -------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAV 302
                               + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V
Sbjct: 211  RPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV 270

Query: 303  ACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAG 362
             C+QLGC  A++A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAG
Sbjct: 271  VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAG 330

Query: 363  VTCS----------------------DGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400
            V CS                        S L LRL  GG RC G VEV  +   G VCD 
Sbjct: 331  VICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD 390

Query: 401  GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS--CNGNETSLWDCKNWQWG 458
             W   +A+VVCRQLGCG A  TS    ++    +  + L    C+G E+ LW C +  W 
Sbjct: 391  SWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448

Query: 459  GLTCDHYEEAKITCSAHRE--------------------------PRLVGGDIPCSGRVE 492
               C H E+A + CSA                              RLV G   C GRVE
Sbjct: 449  SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508

Query: 493  VKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHES 552
            V +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES
Sbjct: 509  VLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHES 568

Query: 553  HLSLCPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IRLVNG 588
            +L  CP        C HS D GV+CS                            +RLVNG
Sbjct: 569  YLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 628

Query: 589  KTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRH 648
               C+GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A+S PG ARFG+G+G I   
Sbjct: 629  GDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 688

Query: 649  MFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR--PTIP 706
               C+G E ++  CP     +  C   + A VICS +QSQ   S ++    PT    T  
Sbjct: 689  DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT---WPTSHASTAG 745

Query: 707  EESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAI 766
             ES++A      LRLVNGG RC GRVE+ + GSWGT+CDD WD +DA+VVCRQLGCG A 
Sbjct: 746  SESSLA------LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAT 799

Query: 767  NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS--- 823
            +A G+A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS   S   
Sbjct: 800  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 859

Query: 824  ---------------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGV 862
                                 LRL +   R  C GR+EV Y G+WGTV           V
Sbjct: 860  PSPDTWPTSRASTAGSESTLALRLVNGGDR--CRGRVEVLYQGSWGTVCDDYWDTNDANV 917

Query: 863  VCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW------------ 910
            VCRQLGC         +     S P+ +D+V+C      LW CP + W            
Sbjct: 918  VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAG 977

Query: 911  -----EKRLASPSEETWITCDNK-----------IRLQEGPTSCSGRVEIWHGGSWGTVC 954
                  +  ++P  +TW+T +             +RL  G   C GRVE+ + GSWGTVC
Sbjct: 978  VICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVC 1037

Query: 955  DDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWG 1014
            DDSWD +DA VVC+QLGCG A+ A   A FGQG+GPI L++V+C GNES LW CP + W 
Sbjct: 1038 DDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWL 1097

Query: 1015 HSECGHKEDAAVNCTDISVQKT------PQKATTGRSS 1046
               CGH EDA V C+   +  T      P   TT R S
Sbjct: 1098 THNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPS 1135



 Score =  770 bits (1988), Expect = 0.0
 Identities = 414/1020 (40%), Positives = 542/1020 (53%), Gaps = 155/1020 (15%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G+ +C GRVE+  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 102  LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 162  GPIALDDVRCSGHESYLWSCPHNGWLSH-NCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220

Query: 155  ---------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSA 205
                     S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A
Sbjct: 221  PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280

Query: 206  VSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG---- 261
            +S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H+EDAGVICS      
Sbjct: 281  MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340

Query: 262  ------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303
                              + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V 
Sbjct: 341  TPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400

Query: 304  CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363
            C+QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV
Sbjct: 401  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460

Query: 364  TCSDG------------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCD 399
             CS                          S L LRL  GG RC G VEV  Q   G VCD
Sbjct: 461  ICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCD 520

Query: 400  RGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGG 459
              W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  W  
Sbjct: 521  DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 580

Query: 460  LTCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVEVKH 495
              C H E+A + CSA +                          RLV G   C GRVEV +
Sbjct: 581  HNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY 640

Query: 496  GDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLS 555
              +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES+L 
Sbjct: 641  RGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLW 700

Query: 556  LCPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IRLVNGKTP 591
             CP        C H  D GV+CS                            +RLVNG   
Sbjct: 701  SCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR 760

Query: 592  CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFH 651
            C+GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A S PG ARFG+G+G I      
Sbjct: 761  CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVR 820

Query: 652  CTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR--PTIPEES 709
            C+G E ++  CP     +  C   + A VICS +QSQ   S ++    PT    T   ES
Sbjct: 821  CSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT---WPTSRASTAGSES 877

Query: 710  AVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINAT 769
             +A      LRLVNGG RC GRVE+ ++GSWGT+CDD WD +DA+VVCRQLGCG A++A 
Sbjct: 878  TLA------LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAP 931

Query: 770  GSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS------ 823
            G+A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS   S      
Sbjct: 932  GNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRP 991

Query: 824  ----------LRLTSEAS--------REACAGRLEVFYNGAWGTVGKSSMSETTVGVVCR 865
                      L + SE+S         + C GR+EV Y G+WGTV   S       VVCR
Sbjct: 992  DTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCR 1051

Query: 866  QLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC 925
            QLGC         +     S P+ +D+V+C      LW CP   W        E+  + C
Sbjct: 1052 QLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 1111



 Score =  726 bits (1873), Expect = 0.0
 Identities = 379/891 (42%), Positives = 492/891 (55%), Gaps = 134/891 (15%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 234  LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS------------------ 152
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 294  GPIVLDDVRCSGHESYLWSCPHNGWLTH-NCGHSEDAGVICSAPQSRPTPSPDTWPTSHA 352

Query: 153  ----DGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++   A+V+CRQL CG A S 
Sbjct: 353  STAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 412

Query: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261
             G++ FG+GSGPI  DD+ C+G ES LW+C H GW  HNC H+EDAGVICS         
Sbjct: 413  PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPS 472

Query: 262  -----------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVAC 304
                             + L+LRLV+G   C GR+EV +QG WGT+CDD WD+ DA V C
Sbjct: 473  PDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVC 532

Query: 305  KQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVT 364
            +QLGC  A++A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAGV 
Sbjct: 533  RQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVI 592

Query: 365  CSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGW 402
            CS                        S L LRL  GG RC G VEV  +   G VCD  W
Sbjct: 593  CSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYW 652

Query: 403  GLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTC 462
               +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  W    C
Sbjct: 653  DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 712

Query: 463  DHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVEVKHGDT 498
             H+E+A + CSA +                          RLV G   C GRVEV +  +
Sbjct: 713  GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGS 772

Query: 499  WGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCP 558
            WG++CD  +    A+V+CR+L CG   S  G A FG+G+G I  ++ +C GHES+L  CP
Sbjct: 773  WGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP 832

Query: 559  VAPRPEGTCSHSRDVGVVCSRYTE------------------------IRLVNGKTPCEG 594
                    C H  D GV+CS                            +RLVNG   C G
Sbjct: 833  HNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRG 892

Query: 595  RVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTG 654
            RVE+   G+WG++C+ +WD  DA+V+C+QL CG A+S PG A+FG+G+G I      C+G
Sbjct: 893  RVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSG 952

Query: 655  TEQHMGDCPVTALGASLCPSEQVASVICSGNQSQ------TLSSCNSSSLGPTRPTIPEE 708
             E ++  CP     +  C   + A VICS  QSQ      T  + N  +L     T+  E
Sbjct: 953  HESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPAL-----TVGSE 1007

Query: 709  SAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINA 768
            S++A      LRLVNGG RC GRVE+ + GSWGT+CDDSWD +DA+VVCRQLGCG A++A
Sbjct: 1008 SSLA------LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 1061

Query: 769  TGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
             G+A FG+G+GPI LD+++C+G ES +W C   GW   NC H EDAGVICS
Sbjct: 1062 PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1112



 Score =  627 bits (1616), Expect = e-179
 Identities = 359/912 (39%), Positives = 465/912 (50%), Gaps = 142/912 (15%)

Query: 25   SPFTI-TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSME 83
            SP T+ T+ L  S     SSL      LRLV+G ++C GRVEV  Q  WGTVC++ W   
Sbjct: 472  SPDTLPTITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 526

Query: 84   AVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143
              +V+C QLGC  A+ APG A    GSG I +D V C G+ES LW C H+GW  H NC H
Sbjct: 527  DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH-NCGH 585

Query: 144  QQDAGVTCSDG----------------------SNLEMRLTRGGNMCSGRIEIKFQGRWG 181
             +DAGV CS                        S+L +RL  GG+ C GR+E+ ++G WG
Sbjct: 586  SEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWG 645

Query: 182  TVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQ 241
            TVCDD ++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H 
Sbjct: 646  TVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHN 705

Query: 242  GWGKHNCDHAEDAGVICSKG----------------------ADLSLRLVDGVTECSGRL 279
            GW  HNC H EDAGVICS                        + L+LRLV+G   C GR+
Sbjct: 706  GWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRV 765

Query: 280  EVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHE 339
            EV ++G WGT+CDD WD+ DA V C+QLGC  A +A G     +G G I LD V C GHE
Sbjct: 766  EVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 825

Query: 340  PAVWQCKHHEWGKHYCNHNEDAGVTCSDG----------------------SDLELRLRG 377
              +W C H+ W  H C H+EDAGV CS                        S L LRL  
Sbjct: 826  SYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVN 885

Query: 378  GGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWL 437
            GG RC G VEV  Q   G VCD  W   +A+VVCRQLGCG A+           +    L
Sbjct: 886  GGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVL 945

Query: 438  FLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP------------------- 478
                C+G+E+ LW C +  W    C H+E+A + CSA +                     
Sbjct: 946  DDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVG 1005

Query: 479  -------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGA 531
                   RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG  +S  G A
Sbjct: 1006 SESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNA 1065

Query: 532  HFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTP 591
             FG+G+G I  ++ +C G+ES+L  CP        C H  D GV+CS       +N  T 
Sbjct: 1066 RFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ----INSTTT 1121

Query: 592  CEGRVELKTLGAWGSLCNSHWDIEDAHVLC--------QQLKCGVALSTPGGARFGKGNG 643
                    T     S C                        KC   +    G R   G  
Sbjct: 1122 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFS 1181

Query: 644  QIWRHMFH-CTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR 702
             +     H C+     + D    +L +SL     +   IC+  +    SS N       R
Sbjct: 1182 NLKLEAHHNCSFDYVEIFD---GSLNSSL-----LLGKICNDTRQIFTSSYN-------R 1226

Query: 703  PTIPEESAVACIESG------------QLRLVN---GGGRCAGRVEIYHEGSWGTICDDS 747
             TI   S ++   +G             LRLVN     G CAGRVEIYH G+WGT+CDDS
Sbjct: 1227 MTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDS 1286

Query: 748  WDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQN 807
            W + +A VVCRQLGCG A++A G+A+FG G+GPI LD+++C+G ES +WQC + GW   N
Sbjct: 1287 WTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHN 1346

Query: 808  CRHKEDAGVICS 819
            C H+EDAGVICS
Sbjct: 1347 CNHREDAGVICS 1358



 Score =  620 bits (1599), Expect = e-177
 Identities = 367/1023 (35%), Positives = 502/1023 (49%), Gaps = 176/1023 (17%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A  APG A    GS
Sbjct: 363  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154
            G I +D V C G ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 423  GPIVLDDVRCSGYESYLWSCPHNGWLSH-NCQHSEDAGVICSAAHSWSTPSPDTLPTITL 481

Query: 155  --------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAV 206
                    S+L +RL  GG+ C GR+E+ +QG WGTVCDD+++ + A+V+CRQL CG A+
Sbjct: 482  PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541

Query: 207  SFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG----- 261
            S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H+EDAGVICS       
Sbjct: 542  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 601

Query: 262  -----------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVAC 304
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C
Sbjct: 602  PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVC 661

Query: 305  KQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVT 364
            +QLGC  A++A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAGV 
Sbjct: 662  RQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 721

Query: 365  CSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGW 402
            CS                        S L LRL  GG RC G VEV  +   G VCD  W
Sbjct: 722  CSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYW 781

Query: 403  GLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS--CNGNETSLWDCKNWQWGGL 460
               +A+VVCRQLGCG A  TS    ++    +  + L    C+G+E+ LW C +  W   
Sbjct: 782  DTNDANVVCRQLGCGWA--TSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 839

Query: 461  TCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVEVKHG 496
             C H+E+A + CSA +                          RLV G   C GRVEV + 
Sbjct: 840  NCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQ 899

Query: 497  DTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSL 556
             +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES+L  
Sbjct: 900  GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWS 959

Query: 557  CPVAPRPEGTCSHSRDVGVVCSRYTE--------------------------IRLVNGKT 590
            CP        C H  D GV+CS                              +RLVNG  
Sbjct: 960  CPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGD 1019

Query: 591  PCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMF 650
             C GRVE+   G+WG++C+  WD  DA+V+C+QL CG A+S PG ARFG+G+G I     
Sbjct: 1020 RCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV 1079

Query: 651  HCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESA 710
             C+G E ++  CP        C   + A VICS  Q   ++S  +    PT  T    S+
Sbjct: 1080 RCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ---INSTTTDWWHPTTTTTARPSS 1136

Query: 711  VACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR-QLGCGEAINAT 769
                             C G +  Y  G++ +    ++  ++A  V   ++  G  IN  
Sbjct: 1137 ----------------NCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLG 1179

Query: 770  GS-----AHF-----------GEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKED 813
             S     AH            G     + L ++ CN       Q  +  + +     + D
Sbjct: 1180 FSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRSD 1234

Query: 814  AGVICSEFMS----------LRLTS-EASREACAGRLEVFYNGAWGTVGKSSMSETTVGV 862
                 + F++          LRL +  +S   CAGR+E+++ G WGTV   S +     V
Sbjct: 1235 ISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEV 1294

Query: 863  VCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETW 922
            VCRQLGC         +   + S P+ +D+V+C     TLWQC +  W     +  E+  
Sbjct: 1295 VCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG 1354

Query: 923  ITC 925
            + C
Sbjct: 1355 VIC 1357



 Score =  554 bits (1428), Expect = e-157
 Identities = 314/793 (39%), Positives = 410/793 (51%), Gaps = 114/793 (14%)

Query: 364  TCSDGSD--LELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALK 421
            T ++GSD  L LRL  G  RC G VE+  +   G VCD  W   +A+VVCRQLGCG A+ 
Sbjct: 91   TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 150

Query: 422  TSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP--- 478
                 +    +    L    C+G+E+ LW C +  W    C H E+A + CSA +     
Sbjct: 151  APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTL 210

Query: 479  ------------------------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASV 514
                                    RLV G   C GRVEV +  +WG++CD  +    A+V
Sbjct: 211  RPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV 270

Query: 515  LCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVG 574
            +CR+L CG  +S  G A FG+G+G I  ++ +C GHES+L  CP        C HS D G
Sbjct: 271  VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAG 330

Query: 575  VVCSRYTE------------------------IRLVNGKTPCEGRVELKTLGAWGSLCNS 610
            V+CS                            +RLVNG   C+GRVE+   G+WG++C+ 
Sbjct: 331  VICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD 390

Query: 611  HWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGAS 670
             WD  DA+V+C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     + 
Sbjct: 391  SWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH 450

Query: 671  LCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG-QLRLVNGGGRCA 729
             C   + A VICS   S +  S +      T PTI   ++    ES   LRLVNGG RC 
Sbjct: 451  NCQHSEDAGVICSAAHSWSTPSPD------TLPTITLPASTVGSESSLALRLVNGGDRCQ 504

Query: 730  GRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCN 789
            GRVE+ ++GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+
Sbjct: 505  GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 564

Query: 790  GKESRIWQCHSHGWGQQNCRHKEDAGVICS------------------------EFMSLR 825
            G ES +W C  +GW   NC H EDAGVICS                          ++LR
Sbjct: 565  GHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALR 624

Query: 826  LTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMS 885
            L +   R  C GR+EV Y G+WGTV           VVCRQLGC         +     S
Sbjct: 625  LVNGGDR--CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 682

Query: 886  IPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRLASPSEETWITCDNK 928
             P+ +D+V+C      LW CP + W                  +   +PS +TW T    
Sbjct: 683  GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHAS 742

Query: 929  ---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAF 979
                     +RL  G   C GRVE+ + GSWGTVCDD WD +DA VVC+QLGCG A  A 
Sbjct: 743  TAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAP 802

Query: 980  KEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQK 1039
              A FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    Q TP  
Sbjct: 803  GNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSP 862

Query: 1040 AT--TGRSSRQSS 1050
             T  T R+S   S
Sbjct: 863  DTWPTSRASTAGS 875



 Score =  320 bits (820), Expect = 5e-87
 Identities = 178/436 (40%), Positives = 224/436 (51%), Gaps = 59/436 (13%)

Query: 663  PVTALGASLCPSEQVASVICSGN----QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQ 718
            P  A G+       + S +  G+    +S   S+    SL P+  T+    A        
Sbjct: 42   PTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLA 101

Query: 719  LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGT 778
            LRLVNG GRC GRVEI + GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+
Sbjct: 102  LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161

Query: 779  GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS------------------- 819
            GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS                   
Sbjct: 162  GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221

Query: 820  --------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCAD 871
                      ++LRL +   R  C GR+EV Y G+WGTV           VVCRQLGC  
Sbjct: 222  PVPTEGSESSLALRLVNGGDR--CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279

Query: 872  KGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRL 914
                   +     S P+ +D+V+C      LW CP + W                  +  
Sbjct: 280  AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339

Query: 915  ASPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQV 965
             +PS +TW T             +RL  G   C GRVE+ + GSWGTVCDDSWD  DA V
Sbjct: 340  PTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANV 399

Query: 966  VCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAA 1025
            VC+QLGCG A  A   A FGQG+GPI L++V+C G ES LW CP   W    C H EDA 
Sbjct: 400  VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAG 459

Query: 1026 VNCTDISVQKTPQKAT 1041
            V C+      TP   T
Sbjct: 460  VICSAAHSWSTPSPDT 475



 Score =  130 bits (328), Expect = 5e-30
 Identities = 54/92 (58%), Positives = 69/92 (75%)

Query: 938  CSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVK 997
            C+GRVEI+HGG+WGTVCDDSW + +A+VVC+QLGCG A+ A   A FG G+GPI L++V+
Sbjct: 1267 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1326

Query: 998  CKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029
            C G ES+LW C  R W    C H+EDA V C+
Sbjct: 1327 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1358



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%)

Query: 583  IRLVNGKTP---CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
            +RLVN  +    C GRVE+   G WG++C+  W I++A V+C+QL CG A+S  G A FG
Sbjct: 1255 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1314

Query: 640  KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
             G+G I      C+GTE  +  C      +  C   + A VICSGN   T
Sbjct: 1315 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1364



 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 44/110 (40%), Positives = 58/110 (52%), Gaps = 3/110 (2%)

Query: 369  SDLELRLRGGGSR---CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQ 425
            SD  LRL    S    CAG VE+      G VCD  W ++EA+VVCRQLGCG A+     
Sbjct: 1251 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1310

Query: 426  VYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAH 475
             Y    +    L    C+G E++LW C+N  W    C+H E+A + CS +
Sbjct: 1311 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1360


>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
          Length = 1788

 Score =  783 bits (2023), Expect = 0.0
 Identities = 442/1141 (38%), Positives = 588/1141 (51%), Gaps = 182/1141 (15%)

Query: 72   WGTVCNNG-W---SMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESAL 127
            WG V + G W   + +  S+I +++   T +     A  S     + ++     G+  +L
Sbjct: 14   WGQVLSTGGWIPRTTDYASLIPSEVPLDTTV-----AEGSPFPSELTLESTVAEGSPISL 68

Query: 128  WDCKHDGWGKHSNCTHQQDAGVTCSDGSN--LEMRLTRGGNMCSGRIEIKFQGRWGTVCD 185
                     + S    +     T ++GS+  L +RL  G   C GR+EI ++G WGTVCD
Sbjct: 69   ESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCD 128

Query: 186  DNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGK 245
            D+++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  
Sbjct: 129  DSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLS 188

Query: 246  HNCDHAEDAGVICSKG-------------------------ADLSLRLVDGVTECSGRLE 280
            HNC H EDAGVICS                           + L+LRLV+G   C GR+E
Sbjct: 189  HNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVE 248

Query: 281  VRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEP 340
            V ++G WGT+CDD WD+ DA V C+QLGC  A++A G     +G G I LD V C GHE 
Sbjct: 249  VLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 308

Query: 341  AVWQCKHHEWGKHYCNHNEDAGVTCS----------------------DGSDLELRLRGG 378
             +W C H+ W  H C H+EDAGV CS                        S L LRL  G
Sbjct: 309  YLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 368

Query: 379  GSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLF 438
            G RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS    ++    +  + 
Sbjct: 369  GDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIV 426

Query: 439  LSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHRE------------------- 477
            L    C+G E+ LW C +  W    C H E+A + CSA                      
Sbjct: 427  LDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTV 486

Query: 478  -------PRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGG 530
                    RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG  +   G 
Sbjct: 487  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 546

Query: 531  AHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYT--------- 581
            A FG+G+G I  ++ +C G+ES+L  CP        C HS D GV+CS            
Sbjct: 547  ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPR 606

Query: 582  ------------------EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQ 623
                               +RLVNG   C+GRVE+   G+WG++C+  WD  DA+V+C+Q
Sbjct: 607  SWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 666

Query: 624  LKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICS 683
            L CG A S PG ARFG+G+G I      C+G E ++  CP     +  C   + A VICS
Sbjct: 667  LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 726

Query: 684  GNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTI 743
              QS+      S+    T PT    S      S  LRLVNGG RC GRVE+ ++GSWGT+
Sbjct: 727  AAQSR------STPRPDTWPT-SHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTV 779

Query: 744  CDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGW 803
            CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G ES +W C  +GW
Sbjct: 780  CDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGW 839

Query: 804  GQQNCRHKEDAGVICS------------------------EFMSLRLTSEASREACAGRL 839
               NC H EDAGVICS                          ++LRL +   R  C GR+
Sbjct: 840  LSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDR--CRGRV 897

Query: 840  EVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGP 899
            EV Y G+WGTV           VVCRQLGC         +     S P+ +D+V+C    
Sbjct: 898  EVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHE 957

Query: 900  DTLWQCPSSPW-----------------EKRLASPSEETWITCD-----------NKIRL 931
              LW CP + W                  +  ++P  +TW+T +             +RL
Sbjct: 958  SYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRL 1017

Query: 932  QEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPI 991
              G   C GRVE+ + GSWGTVCDDSWD +DA VVC+QLGCG A+ A   A FGQG+GPI
Sbjct: 1018 VNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI 1077

Query: 992  WLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKT------PQKATTGRS 1045
             L++V+C GNES LW CP + W    CGH EDA V C+   +  T      P   TT R 
Sbjct: 1078 VLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARP 1137

Query: 1046 S 1046
            S
Sbjct: 1138 S 1138



 Score =  766 bits (1979), Expect = 0.0
 Identities = 415/1023 (40%), Positives = 543/1023 (53%), Gaps = 158/1023 (15%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G+ +C GRVE+  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 102  LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS------------------ 152
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 162  GPIALDDVRCSGHESYLWSCPHNGWLSH-NCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220

Query: 153  -------DGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSA 205
                     S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A
Sbjct: 221  PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280

Query: 206  VSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------ 259
            +S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H+EDAGVICS      
Sbjct: 281  MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340

Query: 260  ----------------KGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303
                              + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V 
Sbjct: 341  TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400

Query: 304  CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363
            C+QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV
Sbjct: 401  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460

Query: 364  TCS------------------------DGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCD 399
             CS                          S L LRL  GG RC G VEV  +   G VCD
Sbjct: 461  ICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 520

Query: 400  RGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGG 459
              W   +A+VVCRQLGCG A+           +    L    C+GNE+ LW C +  W  
Sbjct: 521  DSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLS 580

Query: 460  LTCDHYEEAKITCSAHR---------------------------EPRLVGGDIPCSGRVE 492
              C H E+A + CSA +                             RLV G   C GRVE
Sbjct: 581  HNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVE 640

Query: 493  VKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHES 552
            V +  +WG++CD  +    A+V+CR+L CG   S  G A FG+G+G I  ++ +C GHES
Sbjct: 641  VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHES 700

Query: 553  HLSLCPVAPRPEGTCSHSRDVGVVC----SRYT--------------------EIRLVNG 588
            +L  CP        C H  D GV+C    SR T                     +RLVNG
Sbjct: 701  YLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNG 760

Query: 589  KTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRH 648
               C+GRVE+   G+WG++C+  WD  DA+V+C+QL CG A+S PG ARFG+G+G I   
Sbjct: 761  GDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 820

Query: 649  MFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPT--RPTIP 706
               C+G E ++  CP     +  C   + A VICS +QS+   S ++    PT    T  
Sbjct: 821  DVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT---WPTSRASTAG 877

Query: 707  EESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAI 766
             ES +A      LRLVNGG RC GRVE+ ++GSWGT+CDD WD +DA+VVCRQLGCG A+
Sbjct: 878  SESTLA------LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAM 931

Query: 767  NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS--- 823
            +A G+A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS   S   
Sbjct: 932  SAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQST 991

Query: 824  -------------LRLTSEAS--------REACAGRLEVFYNGAWGTVGKSSMSETTVGV 862
                         L + SE+S         + C GR+EV Y G+WGTV   S       V
Sbjct: 992  PRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANV 1051

Query: 863  VCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETW 922
            VCRQLGC         +     S P+ +D+V+C      LW CP   W        E+  
Sbjct: 1052 VCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAG 1111

Query: 923  ITC 925
            + C
Sbjct: 1112 VIC 1114



 Score =  626 bits (1614), Expect = e-179
 Identities = 359/915 (39%), Positives = 466/915 (50%), Gaps = 145/915 (15%)

Query: 25   SPFTI-TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSME 83
            SP T+ T+ L  S     SSL      LRLV+G ++C GRVEV  +  WGTVC++ W   
Sbjct: 472  SPDTLPTITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 526

Query: 84   AVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143
              +V+C QLGC  A+ APG A    GSG I +D V C GNES LW C H+GW  H NC H
Sbjct: 527  DANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSH-NCGH 585

Query: 144  QQDAGVTCS-------------------------DGSNLEMRLTRGGNMCSGRIEIKFQG 178
             +DAGV CS                           S+L +RL  GG+ C GR+E+ ++G
Sbjct: 586  SEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRG 645

Query: 179  RWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNC 238
             WGTVCDD+++ + A+V+CRQL CG A S  G++ FG+GSGPI  DD+ C+G+ES LW+C
Sbjct: 646  SWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSC 705

Query: 239  KHQGWGKHNCDHAEDAGVICSKG----------------------ADLSLRLVDGVTECS 276
             + GW  HNC H EDAGVICS                        + L+LRLV+G   C 
Sbjct: 706  PNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQ 765

Query: 277  GRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQ 336
            GR+EV +QG WGT+CDD WD+ DA V C+QLGC  A++A G     +G G I LD V C 
Sbjct: 766  GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 825

Query: 337  GHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDG----------------------SDLELR 374
            GHE  +W C H+ W  H C H+EDAGV CS                        S L LR
Sbjct: 826  GHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALR 885

Query: 375  LRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATN 434
            L  GG RC G VEV  Q   G VCD  W   +A+VVCRQLGCG A+           +  
Sbjct: 886  LVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGP 945

Query: 435  TWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP---------------- 478
              L    C+G+E+ LW C +  W    C H+E+A + CSA +                  
Sbjct: 946  IVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPAL 1005

Query: 479  ----------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSIL 528
                      RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG  +S  
Sbjct: 1006 TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 1065

Query: 529  GGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNG 588
            G A FG+G+G I  ++ +C G+ES+L  CP        C H  D GV+CS       +N 
Sbjct: 1066 GNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ----INS 1121

Query: 589  KTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLC--------QQLKCGVALSTPGGARFGK 640
             T         T     S C                        KC   +    G R   
Sbjct: 1122 TTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINL 1181

Query: 641  GNGQIWRHMFH-CTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLG 699
            G   +     H C+     + D    +L +SL     +   IC+  +    SS N     
Sbjct: 1182 GFSNLKLEAHHNCSFDYVEIFD---GSLNSSL-----LLGKICNDTRQIFTSSYN----- 1228

Query: 700  PTRPTIPEESAVACIESG------------QLRLVN---GGGRCAGRVEIYHEGSWGTIC 744
              R TI   S ++   +G             LRLVN     G CAGRVEIYH G+WGT+C
Sbjct: 1229 --RMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVC 1286

Query: 745  DDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWG 804
            DDSW + +A VVCRQLGCG A++A G+A+FG G+GPI LD+++C+G ES +WQC + GW 
Sbjct: 1287 DDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWF 1346

Query: 805  QQNCRHKEDAGVICS 819
              NC H+EDAGVICS
Sbjct: 1347 SHNCNHREDAGVICS 1361



 Score =  617 bits (1590), Expect = e-176
 Identities = 366/1024 (35%), Positives = 497/1024 (48%), Gaps = 175/1024 (17%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A  APG A    GS
Sbjct: 363  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154
            G I +D V C G ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 423  GPIVLDDVRCSGYESYLWSCPHNGWLSH-NCQHSEDAGVICSAAHSWSTPSPDTLPTITL 481

Query: 155  --------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAV 206
                    S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++ + A+V+CRQL CG A+
Sbjct: 482  PASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541

Query: 207  SFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------- 259
               G++ FG+GSGPI  DD+ C+GNES LW+C H GW  HNC H+EDAGVICS       
Sbjct: 542  LAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPT 601

Query: 260  ----------------KGAD--LSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAA 301
                            KG +  L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA 
Sbjct: 602  PIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 661

Query: 302  VACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDA 361
            V C+QLGC  A +A G     +G G I LD V C GHE  +W C ++ W  H C H+EDA
Sbjct: 662  VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDA 721

Query: 362  GVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCD 399
            GV CS                        S L LRL  GG RC G VEV  Q   G VCD
Sbjct: 722  GVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCD 781

Query: 400  RGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGG 459
              W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  W  
Sbjct: 782  DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 841

Query: 460  LTCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVEVKH 495
              C H E+A + CSA +                          RLV G   C GRVEV +
Sbjct: 842  HNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLY 901

Query: 496  GDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLS 555
              +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES+L 
Sbjct: 902  QGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLW 961

Query: 556  LCPVAPRPEGTCSHSRDVGVVCSRYTE--------------------------IRLVNGK 589
             CP        C H  D GV+CS                              +RLVNG 
Sbjct: 962  SCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGG 1021

Query: 590  TPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHM 649
              C GRVE+   G+WG++C+  WD  DA+V+C+QL CG A+S PG ARFG+G+G I    
Sbjct: 1022 DRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD 1081

Query: 650  FHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEES 709
              C+G E ++  CP        C   + A VICS  Q   ++S  +    PT  T    S
Sbjct: 1082 VRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ---INSTTTDWWHPTTTTTARPS 1138

Query: 710  AVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR-QLGCGEAINA 768
            +                 C G +  Y  G++ +    ++  ++A  V   ++  G  IN 
Sbjct: 1139 S----------------NCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINL 1181

Query: 769  TGS-----AHF-----------GEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKE 812
              S     AH            G     + L ++ CN       Q  +  + +     + 
Sbjct: 1182 GFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRS 1236

Query: 813  DAGVICSEFMS----------LRLTS-EASREACAGRLEVFYNGAWGTVGKSSMSETTVG 861
            D     + F++          LRL +  +S   CAGR+E+++ G WGTV   S +     
Sbjct: 1237 DISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAE 1296

Query: 862  VVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEET 921
            VVCRQLGC         +   + S P+ +D+V+C     TLWQC +  W     +  E+ 
Sbjct: 1297 VVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDA 1356

Query: 922  WITC 925
             + C
Sbjct: 1357 GVIC 1360



 Score =  130 bits (328), Expect = 5e-30
 Identities = 54/92 (58%), Positives = 69/92 (75%)

Query: 938  CSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVK 997
            C+GRVEI+HGG+WGTVCDDSW + +A+VVC+QLGCG A+ A   A FG G+GPI L++V+
Sbjct: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1329

Query: 998  CKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029
            C G ES+LW C  R W    C H+EDA V C+
Sbjct: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%)

Query: 583  IRLVNGKTP---CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
            +RLVN  +    C GRVE+   G WG++C+  W I++A V+C+QL CG A+S  G A FG
Sbjct: 1258 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1317

Query: 640  KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
             G+G I      C+GTE  +  C      +  C   + A VICSGN   T
Sbjct: 1318 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1367



 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 44/110 (40%), Positives = 58/110 (52%), Gaps = 3/110 (2%)

Query: 369  SDLELRLRGGGSR---CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQ 425
            SD  LRL    S    CAG VE+      G VCD  W ++EA+VVCRQLGCG A+     
Sbjct: 1254 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1313

Query: 426  VYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAH 475
             Y    +    L    C+G E++LW C+N  W    C+H E+A + CS +
Sbjct: 1314 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1363


>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
          Length = 1662

 Score =  721 bits (1862), Expect = 0.0
 Identities = 378/900 (42%), Positives = 494/900 (54%), Gaps = 143/900 (15%)

Query: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
           LRLV+G+ +C GRVE+  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161

Query: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154
           G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 162 GPIALDDVRCSGHESYLWSCPHNGWLSH-NCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220

Query: 155 ---------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSA 205
                    S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A
Sbjct: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280

Query: 206 VSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------ 259
           +S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H+EDAGVICS      
Sbjct: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340

Query: 260 ----------------KGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V 
Sbjct: 341 TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400

Query: 304 CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363
           C+QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV
Sbjct: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460

Query: 364 TCS------------------------------DGSDLELRLRGGGSRCAGTVEVEIQRL 393
            CS                                S L LRL  GG RC G VEV  +  
Sbjct: 461 ICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGS 520

Query: 394 LGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCK 453
            G VCD  W   +A+VVCRQLGCG A+           +    L    C+GNE+ LW C 
Sbjct: 521 WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP 580

Query: 454 NWQWGGLTCDHYEEAKITCSAHREP------------------------RLVGGDIPCSG 489
           +  W    C H E+A + CSA +                          RLV G   C G
Sbjct: 581 HNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQG 640

Query: 490 RVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEG 549
           RVEV +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C G
Sbjct: 641 RVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 700

Query: 550 HESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IRL 585
           HES+L  CP        C HS D GV+CS                            +RL
Sbjct: 701 HESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRL 760

Query: 586 VNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQI 645
           VNG   C GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A+S PG A+FG+G+G I
Sbjct: 761 VNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPI 820

Query: 646 WRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQ------TLSSCNSSSLG 699
                 C+G E ++  CP     +  C   + A VICS  QSQ      T  + N  +L 
Sbjct: 821 VLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPAL- 879

Query: 700 PTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQ 759
               T+  ES++A      LRLVNGG RC GRVE+ + GSWGT+CDDSWD +DA+VVCRQ
Sbjct: 880 ----TVGSESSLA------LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 929

Query: 760 LGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
           LGCG A++A G+A FG+G+GPI LD+++C+G ES +W C   GW   NC H EDAGVICS
Sbjct: 930 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 989



 Score =  661 bits (1705), Expect = 0.0
 Identities = 378/991 (38%), Positives = 510/991 (51%), Gaps = 153/991 (15%)

Query: 72  WGTVCNNG-W---SMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESAL 127
           WG V + G W   + +  S+I +++   T +     A  S     + ++     G+  +L
Sbjct: 14  WGQVLSTGGWIPRTTDYASLIPSEVPLDTTV-----AEGSPFPSELTLESTVAEGSPISL 68

Query: 128 WDCKHDGWGKHSNCTHQQDAGVTCSDGSN--LEMRLTRGGNMCSGRIEIKFQGRWGTVCD 185
                    + S    +     T ++GS+  L +RL  G   C GR+EI ++G WGTVCD
Sbjct: 69  ESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCD 128

Query: 186 DNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGK 245
           D+++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  
Sbjct: 129 DSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLS 188

Query: 246 HNCDHAEDAGVICSKG-------------------------ADLSLRLVDGVTECSGRLE 280
           HNC H EDAGVICS                           + L+LRLV+G   C GR+E
Sbjct: 189 HNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVE 248

Query: 281 VRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEP 340
           V ++G WGT+CDD WD+ DA V C+QLGC  A++A G     +G G I LD V C GHE 
Sbjct: 249 VLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 308

Query: 341 AVWQCKHHEWGKHYCNHNEDAGVTCS----------------------DGSDLELRLRGG 378
            +W C H+ W  H C H+EDAGV CS                        S L LRL  G
Sbjct: 309 YLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 368

Query: 379 GSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLF 438
           G RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS    ++    +  + 
Sbjct: 369 GDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIV 426

Query: 439 LSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHRE------------------- 477
           L    C+G E+ LW C +  W    C H E+A + CSA                      
Sbjct: 427 LDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTIT 486

Query: 478 -------------PRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTV 524
                         RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG  
Sbjct: 487 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 546

Query: 525 VSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC----SRY 580
           +   G A FG+G+G I  ++ +C G+ES+L  CP        C HS D GV+C    SR 
Sbjct: 547 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRS 606

Query: 581 T--------------------EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVL 620
           T                     +RLVNG   C+GRVE+   G+WG++C+  WD  DA+V+
Sbjct: 607 TPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVV 666

Query: 621 CQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASV 680
           C+QL CG A+S PG ARFG+G+G I      C+G E ++  CP     +  C   + A V
Sbjct: 667 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGV 726

Query: 681 ICSGNQSQTLSSCNSSSLGPT--RPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEG 738
           ICS +QS+   S ++    PT    T   ES +A      LRLVNGG RC GRVE+ ++G
Sbjct: 727 ICSASQSRPTPSPDT---WPTSRASTAGSESTLA------LRLVNGGDRCRGRVEVLYQG 777

Query: 739 SWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQC 798
           SWGT+CDD WD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G ES +W C
Sbjct: 778 SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSC 837

Query: 799 HSHGWGQQNCRHKEDAGVICSEFMS----------------LRLTSEAS--------REA 834
             +GW   NC H EDAGVICS   S                L + SE+S         + 
Sbjct: 838 PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDR 897

Query: 835 CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQ 894
           C GR+EV Y G+WGTV   S       VVCRQLGC         +     S P+ +D+V+
Sbjct: 898 CRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR 957

Query: 895 CPKGPDTLWQCPSSPWEKRLASPSEETWITC 925
           C      LW CP   W        E+  + C
Sbjct: 958 CSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 988



 Score =  659 bits (1700), Expect = 0.0
 Identities = 367/929 (39%), Positives = 481/929 (51%), Gaps = 150/929 (16%)

Query: 259  SKGAD--LSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAI 316
            ++G+D  L+LRLV+G   C GR+E+ ++G WGT+CDD WD+ DA V C+QLGC  A++A 
Sbjct: 93   AEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 152

Query: 317  GRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS---------- 366
            G     +G G I LD V C GHE  +W C H+ W  H C H EDAGV CS          
Sbjct: 153  GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRP 212

Query: 367  -------------DGSD--LELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVC 411
                         +GS+  L LRL  GG RC G VEV  +   G VCD  W   +A+VVC
Sbjct: 213  ESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVC 272

Query: 412  RQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKIT 471
            RQLGCG A+           +    L    C+G+E+ LW C +  W    C H E+A + 
Sbjct: 273  RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVI 332

Query: 472  CSAHREP------------------------RLVGGDIPCSGRVEVKHGDTWGSICDSDF 507
            CSA +                          RLV G   C GRVEV +  +WG++CD  +
Sbjct: 333  CSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW 392

Query: 508  SLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTC 567
                A+V+CR+L CG   S  G A FG+G+G I  ++ +C G+ES+L  CP        C
Sbjct: 393  DTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNC 452

Query: 568  SHSRDVGVVCSRYTE--------------------------------IRLVNGKTPCEGR 595
             HS D GV+CS                                    +RLVNG   C+GR
Sbjct: 453  QHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGR 512

Query: 596  VELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGT 655
            VE+   G+WG++C+  WD  DA+V+C+QL CG A+  PG ARFG+G+G I      C+G 
Sbjct: 513  VEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGN 572

Query: 656  EQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIE 715
            E ++  CP     +  C   + A VICS  QS+      S+    T PT    S      
Sbjct: 573  ESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSR------STPRPDTWPT-SHASTAGSES 625

Query: 716  SGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFG 775
            S  LRLVNGG RC GRVE+ ++GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG
Sbjct: 626  SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 685

Query: 776  EGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS---------------- 819
            +G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS                
Sbjct: 686  QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 745

Query: 820  --------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCAD 871
                      ++LRL +   R  C GR+EV Y G+WGTV           VVCRQLGC  
Sbjct: 746  RASTAGSESTLALRLVNGGDR--CRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGW 803

Query: 872  KGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRL 914
                   +     S P+ +D+V+C      LW CP + W                  +  
Sbjct: 804  AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQ 863

Query: 915  ASPSEETWITCD-----------NKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDA 963
            ++P  +TW+T +             +RL  G   C GRVE+ + GSWGTVCDDSWD +DA
Sbjct: 864  STPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDA 923

Query: 964  QVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKED 1023
             VVC+QLGCG A+ A   A FGQG+GPI L++V+C GNES LW CP + W    CGH ED
Sbjct: 924  NVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHED 983

Query: 1024 AAVNCTDISVQKT------PQKATTGRSS 1046
            A V C+   +  T      P   TT R S
Sbjct: 984  AGVICSATQINSTTTDWWHPTTTTTARPS 1012



 Score =  624 bits (1609), Expect = e-178
 Identities = 350/893 (39%), Positives = 454/893 (50%), Gaps = 144/893 (16%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A  APG A    GS
Sbjct: 363  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154
            G I +D V C G ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 423  GPIVLDDVRCSGYESYLWSCPHNGWLSH-NCQHSEDAGVICSAAHSWSTPSPGERDRTDT 481

Query: 155  --------------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQL 200
                          S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++ + A+V+CRQL
Sbjct: 482  LPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 541

Query: 201  ECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSK 260
             CG A+   G++ FG+GSGPI  DD+ C+GNES LW+C H GW  HNC H+EDAGVICS 
Sbjct: 542  GCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSA 601

Query: 261  G----------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSY 298
                                   + L+LRLV+G   C GR+EV +QG WGT+CDD WD+ 
Sbjct: 602  AQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 661

Query: 299  DAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHN 358
            DA V C+QLGC  A++A G     +G G I LD V C GHE  +W C H+ W  H C H+
Sbjct: 662  DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHS 721

Query: 359  EDAGVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGK 396
            EDAGV CS                        S L LRL  GG RC G VEV  Q   G 
Sbjct: 722  EDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGT 781

Query: 397  VCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQ 456
            VCD  W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  
Sbjct: 782  VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNG 841

Query: 457  WGGLTCDHYEEAKITCSAHREP--------------------------RLVGGDIPCSGR 490
            W    C H+E+A + CSA +                            RLV G   C GR
Sbjct: 842  WLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGR 901

Query: 491  VEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGH 550
            VEV +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C G+
Sbjct: 902  VEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGN 961

Query: 551  ESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNS 610
            ES+L  CP        C H  D GV+CS       +N  T         T     S C  
Sbjct: 962  ESYLWSCPHKGWLTHNCGHHEDAGVICS----ATQINSTTTDWWHPTTTTTARPSSNCGG 1017

Query: 611  HWDIEDAHVLC--------QQLKCGVALSTPGGARFGKGNGQIWRHMFH-CTGTEQHMGD 661
                                  KC   +    G R   G   +     H C+     + D
Sbjct: 1018 FLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFD 1077

Query: 662  CPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG---- 717
                +L +SL     +   IC+  +    SS N       R TI   S ++   +G    
Sbjct: 1078 ---GSLNSSL-----LLGKICNDTRQIFTSSYN-------RMTIHFRSDISFQNTGFLAW 1122

Query: 718  --------QLRLVN---GGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAI 766
                     LRLVN     G CAGRVEIYH G+WGT+CDDSW + +A VVCRQLGCG A+
Sbjct: 1123 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1182

Query: 767  NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
            +A G+A+FG G+GPI LD+++C+G ES +WQC + GW   NC H+EDAGVICS
Sbjct: 1183 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235



 Score =  613 bits (1581), Expect = e-175
 Identities = 364/1027 (35%), Positives = 495/1027 (48%), Gaps = 178/1027 (17%)

Query: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 234  LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293

Query: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS------------------ 152
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 294  GPIVLDDVRCSGHESYLWSCPHNGWLTH-NCGHSEDAGVICSAPQSRPTPSPDTWPTSHA 352

Query: 153  ----DGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++   A+V+CRQL CG A S 
Sbjct: 353  STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 412

Query: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261
             G++ FG+GSGPI  DD+ C+G ES LW+C H GW  HNC H+EDAGVICS         
Sbjct: 413  PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPS 472

Query: 262  -----------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSY 298
                                   + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ 
Sbjct: 473  PGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 532

Query: 299  DAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHN 358
            DA V C+QLGC  A+ A G     +G G I LD V C G+E  +W C H+ W  H C H+
Sbjct: 533  DANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHS 592

Query: 359  EDAGVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGK 396
            EDAGV CS                        S L LRL  GG RC G VEV  Q   G 
Sbjct: 593  EDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGT 652

Query: 397  VCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQ 456
            VCD  W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  
Sbjct: 653  VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 712

Query: 457  WGGLTCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVE 492
            W    C H E+A + CSA +                          RLV G   C GRVE
Sbjct: 713  WLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVE 772

Query: 493  VKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHES 552
            V +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES
Sbjct: 773  VLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 832

Query: 553  HLSLCPVAPRPEGTCSHSRDVGVVCSRYTE--------------------------IRLV 586
            +L  CP        C H  D GV+CS                              +RLV
Sbjct: 833  YLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLV 892

Query: 587  NGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIW 646
            NG   C GRVE+   G+WG++C+  WD  DA+V+C+QL CG A+S PG ARFG+G+G I 
Sbjct: 893  NGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 952

Query: 647  RHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIP 706
                 C+G E ++  CP        C   + A VICS  Q   ++S  +    PT  T  
Sbjct: 953  LDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ---INSTTTDWWHPTTTTTA 1009

Query: 707  EESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR-QLGCGEA 765
              S+                 C G +  Y  G++ +    ++  ++A  V   ++  G  
Sbjct: 1010 RPSS----------------NCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYR 1052

Query: 766  INATGS-----AHF-----------GEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCR 809
            IN   S     AH            G     + L ++ CN       Q  +  + +    
Sbjct: 1053 INLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIH 1107

Query: 810  HKEDAGVICSEFMS----------LRLTS-EASREACAGRLEVFYNGAWGTVGKSSMSET 858
             + D     + F++          LRL +  +S   CAGR+E+++ G WGTV   S +  
Sbjct: 1108 FRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQ 1167

Query: 859  TVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPS 918
               VVCRQLGC         +   + S P+ +D+V+C     TLWQC +  W     +  
Sbjct: 1168 EAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHR 1227

Query: 919  EETWITC 925
            E+  + C
Sbjct: 1228 EDAGVIC 1234



 Score =  559 bits (1441), Expect = e-159
 Identities = 312/780 (40%), Positives = 405/780 (51%), Gaps = 102/780 (13%)

Query: 364  TCSDGSD--LELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALK 421
            T ++GSD  L LRL  G  RC G VE+  +   G VCD  W   +A+VVCRQLGCG A+ 
Sbjct: 91   TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 150

Query: 422  TSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP--- 478
                 +    +    L    C+G+E+ LW C +  W    C H E+A + CSA +     
Sbjct: 151  APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTL 210

Query: 479  ------------------------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASV 514
                                    RLV G   C GRVEV +  +WG++CD  +    A+V
Sbjct: 211  RPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV 270

Query: 515  LCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVG 574
            +CR+L CG  +S  G A FG+G+G I  ++ +C GHES+L  CP        C HS D G
Sbjct: 271  VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAG 330

Query: 575  VVCSRYTE------------------------IRLVNGKTPCEGRVELKTLGAWGSLCNS 610
            V+CS                            +RLVNG   C+GRVE+   G+WG++C+ 
Sbjct: 331  VICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD 390

Query: 611  HWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGAS 670
             WD  DA+V+C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     + 
Sbjct: 391  SWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH 450

Query: 671  LCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG-QLRLVNGGGRCA 729
             C   + A VICS   S +  S        T PTI   ++    ES   LRLVNGG RC 
Sbjct: 451  NCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQ 510

Query: 730  GRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCN 789
            GRVE+ + GSWGT+CDDSWD +DA+VVCRQLGCG A+ A G+A FG+G+GPI LD+++C+
Sbjct: 511  GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCS 570

Query: 790  GKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRL-------TSEASR---------- 832
            G ES +W C  +GW   NC H EDAGVICS   S          TS AS           
Sbjct: 571  GNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALR 630

Query: 833  -----EACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIP 887
                 + C GR+EV Y G+WGTV   S       VVCRQLGC         +     S P
Sbjct: 631  LVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGP 690

Query: 888  MWVDNVQCPKGPDTLWQCPSSPW-----------------EKRLASPSEETWITCDNK-- 928
            + +D+V+C      LW CP + W                  +   +PS +TW T      
Sbjct: 691  IVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTA 750

Query: 929  -------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKE 981
                   +RL  G   C GRVE+ + GSWGTVCDD WD +DA VVC+QLGCG A+ A   
Sbjct: 751  GSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 810

Query: 982  AEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKAT 1041
            A+FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    Q TP+  T
Sbjct: 811  AQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDT 870



 Score =  427 bits (1098), Expect = e-119
 Identities = 223/513 (43%), Positives = 282/513 (54%), Gaps = 74/513 (14%)

Query: 30  TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVIC 89
           T+ L  S     SSL      LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C
Sbjct: 484 TITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 538

Query: 90  NQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGV 149
            QLGC  A+ APG A    GSG I +D V C GNES LW C H+GW  H NC H +DAGV
Sbjct: 539 RQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSH-NCGHSEDAGV 597

Query: 150 TCSDG----------------------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDN 187
            CS                        S+L +RL  GG+ C GR+E+ +QG WGTVCDD+
Sbjct: 598 ICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDS 657

Query: 188 FNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHN 247
           ++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HN
Sbjct: 658 WDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 717

Query: 248 CDHAEDAGVICSKG----------------------ADLSLRLVDGVTECSGRLEVRFQG 285
           C H+EDAGVICS                        + L+LRLV+G   C GR+EV +QG
Sbjct: 718 CGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG 777

Query: 286 EWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQC 345
            WGT+CDD WD+ DA V C+QLGC  A++A G     +G G I LD V C GHE  +W C
Sbjct: 778 SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSC 837

Query: 346 KHHEWGKHYCNHNEDAGVTCS------------------------DGSDLELRLRGGGSR 381
            H+ W  H C H+EDAGV CS                          S L LRL  GG R
Sbjct: 838 PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDR 897

Query: 382 CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS 441
           C G VEV  +   G VCD  W   +A+VVCRQLGCG A+           +    L    
Sbjct: 898 CRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR 957

Query: 442 CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSA 474
           C+GNE+ LW C +  W    C H+E+A + CSA
Sbjct: 958 CSGNESYLWSCPHKGWLTHNCGHHEDAGVICSA 990



 Score =  318 bits (815), Expect = 2e-86
 Identities = 180/439 (41%), Positives = 226/439 (51%), Gaps = 60/439 (13%)

Query: 665  TALGASLCPSE-QVASVICSGN----QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQL 719
            T    S  PSE  + S +  G+    +S   S+    SL P+  T+    A        L
Sbjct: 43   TVAEGSPFPSELTLESTVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLAL 102

Query: 720  RLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTG 779
            RLVNG GRC GRVEI + GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+G
Sbjct: 103  RLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSG 162

Query: 780  PIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS-------------------- 819
            PI LD+++C+G ES +W C  +GW   NC H EDAGVICS                    
Sbjct: 163  PIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPP 222

Query: 820  -------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADK 872
                     ++LRL +   R  C GR+EV Y G+WGTV           VVCRQLGC   
Sbjct: 223  VPTEGSESSLALRLVNGGDR--CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280

Query: 873  GKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRLA 915
                  +     S P+ +D+V+C      LW CP + W                  +   
Sbjct: 281  MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340

Query: 916  SPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVV 966
            +PS +TW T             +RL  G   C GRVE+ + GSWGTVCDDSWD  DA VV
Sbjct: 341  TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400

Query: 967  CQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAV 1026
            C+QLGCG A  A   A FGQG+GPI L++V+C G ES LW CP   W    C H EDA V
Sbjct: 401  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460

Query: 1027 NCTDISVQKTPQKATTGRS 1045
             C+      TP      R+
Sbjct: 461  ICSAAHSWSTPSPGERDRT 479



 Score =  130 bits (328), Expect = 5e-30
 Identities = 54/92 (58%), Positives = 69/92 (75%)

Query: 938  CSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVK 997
            C+GRVEI+HGG+WGTVCDDSW + +A+VVC+QLGCG A+ A   A FG G+GPI L++V+
Sbjct: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1203

Query: 998  CKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029
            C G ES+LW C  R W    C H+EDA V C+
Sbjct: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235



 Score =  108 bits (271), Expect = 2e-23
 Identities = 51/109 (46%), Positives = 69/109 (63%), Gaps = 4/109 (3%)

Query: 47   TDKELRLVDGENK---CSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGW 103
            +D  LRLV+  +    C+GRVE+     WGTVC++ W+++   V+C QLGC  A+ A G 
Sbjct: 1128 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1187

Query: 104  ANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152
            A   +GSG I +D V C G ES LW C++ GW  H NC H++DAGV CS
Sbjct: 1188 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSH-NCNHREDAGVICS 1235



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%)

Query: 583  IRLVNGKTP---CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
            +RLVN  +    C GRVE+   G WG++C+  W I++A V+C+QL CG A+S  G A FG
Sbjct: 1132 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1191

Query: 640  KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
             G+G I      C+GTE  +  C      +  C   + A VICSGN   T
Sbjct: 1192 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1241



 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 44/110 (40%), Positives = 58/110 (52%), Gaps = 3/110 (2%)

Query: 369  SDLELRLRGGGSR---CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQ 425
            SD  LRL    S    CAG VE+      G VCD  W ++EA+VVCRQLGCG A+     
Sbjct: 1128 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1187

Query: 426  VYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAH 475
             Y    +    L    C+G E++LW C+N  W    C+H E+A + CS +
Sbjct: 1188 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1237


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score =  352 bits (903), Expect = 1e-96
 Identities = 210/583 (36%), Positives = 284/583 (48%), Gaps = 63/583 (10%)

Query: 266 LRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGF 325
           LRL DG   C+GRLEV   G WGT+CDDGWD  DAAVAC+QLGC  A+ A G     +G 
Sbjct: 20  LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 326 GHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLELRLRGGGSRCAGT 385
           G +WL  ++C+G+          E     C+H       CS   D        G  CAG 
Sbjct: 80  GPVWLSELACRGN----------EGQLGLCHHRGWKAHICSHEED-------AGVVCAG- 121

Query: 386 VEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGN 445
                QR+     D    L  A      L    + +     ++   A N     ++    
Sbjct: 122 -----QRVANSRDDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQ---NASRKK 173

Query: 446 ETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRLVGGDIPCSGRVEVKHGDTWGSICDS 505
                  K+ +   LT     + ++        RLV G   C+GR+EV HG  WG++CD 
Sbjct: 174 SPRPKQAKSTRAPLLTTGAPRQERL--------RLVSGPHRCAGRLEVWHGGRWGTVCDD 225

Query: 506 DFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEG 565
            + L  A+V CREL CG  ++  GGA FG G G +W ++  C G E  L  CP +P    
Sbjct: 226 GWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRS 285

Query: 566 TCSHSRDVGVVCSRYT-EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQL 624
            C HS D G+VC+     +RL +G   C GR+E+   G WGS+C+  WD+ DA V C++L
Sbjct: 286 NCDHSEDAGLVCTGPAPRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACREL 345

Query: 625 KCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSG 684
            CG AL+ PGGA FG+G+G I      C G E  +  CP    G   C   + A  +C G
Sbjct: 346 GCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDG 405

Query: 685 ---------------------NQSQTLSSCNSSSLGPTRPTIPEESAVACIESG------ 717
                                  S+  S+  S + G    + P  S     E G      
Sbjct: 406 MPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSP 465

Query: 718 QLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSA-HFGE 776
           QLRLV G  +C+GR+E++H+  WGT+CDDSWD+ D+ VVCR+LGCG       +A  FG 
Sbjct: 466 QLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGW 525

Query: 777 GTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
           G GPIWLD++ C G E+ +  C +  WG+ NC H ED GV C+
Sbjct: 526 GAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568



 Score =  336 bits (862), Expect = 6e-92
 Identities = 188/550 (34%), Positives = 258/550 (46%), Gaps = 104/550 (18%)

Query: 583  IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642
            +RL +G   C GR+E+   G WG++C+  WD+ DA V C+QL CG AL+ PGGA FG+G 
Sbjct: 20   LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 643  GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSS------ 696
            G +W     C G E  +G C      A +C  E+ A V+C+G +       ++S      
Sbjct: 80   GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDGAP 139

Query: 697  ------SLGPT-------------------------RPTIPEESAVACIESG-----QLR 720
                   L P+                         RP   + +    + +G     +LR
Sbjct: 140  WPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERLR 199

Query: 721  LVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGP 780
            LV+G  RCAGR+E++H G WGT+CDD WDL DA V CR+LGCG A+ A G A FG G GP
Sbjct: 200  LVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGP 259

Query: 781  IWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRLE 840
            +W+D++ C G E  +  C    WG+ NC H EDAG++C+   + RL        CAGRLE
Sbjct: 260  VWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG-PAPRLRLADGPHGCAGRLE 318

Query: 841  VFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPD 900
            V++ G WG+V   +       V CR+LGC         +     S P+ +D+++C     
Sbjct: 319  VWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNET 378

Query: 901  TLWQCPSSPWEKRLASPSEETWITCDN--------------------------------- 927
             L  CP+ PW +      E+    CD                                  
Sbjct: 379  ALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQ 438

Query: 928  --------------KIRLQEGPTSCSGRVEIWHGGS-------------WGTVCDDSWDL 960
                           +  + GP + S ++ +  G S             WGTVCDDSWD+
Sbjct: 439  APGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDM 498

Query: 961  DDAQVVCQQLGC-GPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECG 1019
             D+ VVC++LGC GP         FG G GPIWL++V C G E+SL DCPA  WG   C 
Sbjct: 499  RDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCA 558

Query: 1020 HKEDAAVNCT 1029
            H ED  V CT
Sbjct: 559  HNEDVGVTCT 568



 Score =  259 bits (661), Expect = 1e-68
 Identities = 131/312 (41%), Positives = 168/312 (53%), Gaps = 32/312 (10%)

Query: 718  QLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEG 777
            +LRL +G   CAGR+E++H G WGT+CDD WDL DA V CRQLGCG A+ A G A FGEG
Sbjct: 19   RLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEG 78

Query: 778  TGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAG 837
             GP+WL E+ C G E ++  CH  GW    C H+EDAGV+C+     R+ +  SR+    
Sbjct: 79   AGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCA---GQRVAN--SRDDSTS 133

Query: 838  RLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPK 897
             L+      W  +       T   +V      A +   NP +  +  S            
Sbjct: 134  PLD---GAPWPGLLLELSPSTEEPLVTH----APRPAGNPQNASRKKS------------ 174

Query: 898  GPDTLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDS 957
                    P     K   +P   T      ++RL  GP  C+GR+E+WHGG WGTVCDD 
Sbjct: 175  --------PRPKQAKSTRAPLLTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDG 226

Query: 958  WDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSE 1017
            WDL DA V C++LGCG AL A   A FG G GP+W+++V C G E +L DCP   WG S 
Sbjct: 227  WDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSN 286

Query: 1018 CGHKEDAAVNCT 1029
            C H EDA + CT
Sbjct: 287  CDHSEDAGLVCT 298



 Score =  230 bits (586), Expect = 6e-60
 Identities = 105/213 (49%), Positives = 140/213 (65%), Gaps = 2/213 (0%)

Query: 159 MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGS 218
           +RL  G + C+GR+E+   GRWGTVCDD +++  A+V CR+L CG A++  G + FG G+
Sbjct: 198 LRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGA 257

Query: 219 GPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGR 278
           GP+W DD+ C G E AL +C    WG+ NCDH+EDAG++C+ G    LRL DG   C+GR
Sbjct: 258 GPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCT-GPAPRLRLADGPHGCAGR 316

Query: 279 LEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGH 338
           LEV   G WG++CDD WD  DAAVAC++LGC  A+ A G     +G G I LD + C+G+
Sbjct: 317 LEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGN 376

Query: 339 EPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDL 371
           E A+  C    WG+H C+H EDAG  C DG  L
Sbjct: 377 ETALRFCPARPWGQHDCHHREDAGAVC-DGMPL 408



 Score =  226 bits (576), Expect = 9e-59
 Identities = 103/210 (49%), Positives = 139/210 (66%), Gaps = 2/210 (0%)

Query: 49  KELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSA 108
           + LRLV G ++C+GR+EV     WGTVC++GW +   +V C +LGC  A+ APG A    
Sbjct: 196 ERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGP 255

Query: 109 GSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMC 168
           G+G +WMD V C G E AL DC    WG+ SNC H +DAG+ C+ G    +RL  G + C
Sbjct: 256 GAGPVWMDDVGCGGGEQALRDCPRSPWGR-SNCDHSEDAGLVCT-GPAPRLRLADGPHGC 313

Query: 169 SGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLIC 228
           +GR+E+   GRWG+VCDD +++  A+V CR+L CG A++  G + FGEGSGPI  DDL C
Sbjct: 314 AGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRC 373

Query: 229 NGNESALWNCKHQGWGKHNCDHAEDAGVIC 258
            GNE+AL  C  + WG+H+C H EDAG +C
Sbjct: 374 RGNETALRFCPARPWGQHDCHHREDAGAVC 403



 Score =  203 bits (516), Expect = 8e-52
 Identities = 98/222 (44%), Positives = 132/222 (59%), Gaps = 5/222 (2%)

Query: 824  LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKA 883
            LRL S   R  CAGRLEV++ G WGTV           V CR+LGC         +    
Sbjct: 198  LRLVSGPHR--CAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGP 255

Query: 884  MSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN---KIRLQEGPTSCSG 940
             + P+W+D+V C  G   L  CP SPW +     SE+  + C     ++RL +GP  C+G
Sbjct: 256  GAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPRLRLADGPHGCAG 315

Query: 941  RVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKG 1000
            R+E+WHGG WG+VCDD+WDL DA V C++LGCG AL A   A FG+G+GPI L++++C+G
Sbjct: 316  RLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRG 375

Query: 1001 NESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATT 1042
            NE++L  CPAR WG  +C H+EDA   C  + +   P  A T
Sbjct: 376  NETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPT 417



 Score =  201 bits (510), Expect = 4e-51
 Identities = 138/426 (32%), Positives = 189/426 (44%), Gaps = 49/426 (11%)

Query: 159 MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGS 218
           +RL  G + C+GR+E+   GRWGTVCDD +++  A+V CRQL CG A++  G + FGEG+
Sbjct: 20  LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 219 GPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVIC-----SKGADLSLRLVDGVT 273
           GP+W  +L C GNE  L  C H+GW  H C H EDAGV+C     +   D S   +DG  
Sbjct: 80  GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDGAP 139

Query: 274 ECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVT--AIGRVNASKGFGHIWLD 331
                LE+    E   +            A +  G P   +     R   +K      L 
Sbjct: 140 WPGLLLELSPSTEEPLVTH----------APRPAGNPQNASRKKSPRPKQAKSTRAPLLT 189

Query: 332 SVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLELRLRGGGSRCAGTVEVEIQ 391
           + + +     +    H   G+    H    G  C DG D    LR     C    E+   
Sbjct: 190 TGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWD----LRDAAVACR---ELGCG 242

Query: 392 RLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWD 451
             L       +G     V    +GCG   +                 L  C  +     +
Sbjct: 243 GALAAPGGARFGPGAGPVWMDDVGCGGGEQA----------------LRDCPRSPWGRSN 286

Query: 452 CKNWQWGGLTCDHYEEAKITCSAHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEA 511
           C + +  GL C        T  A R  RL  G   C+GR+EV HG  WGS+CD  + L  
Sbjct: 287 CDHSEDAGLVC--------TGPAPR-LRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRD 337

Query: 512 ASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSR 571
           A+V CREL CG  ++  GGA FGEG+G I  ++ +C G+E+ L  CP  P  +  C H  
Sbjct: 338 AAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHRE 397

Query: 572 DVGVVC 577
           D G VC
Sbjct: 398 DAGAVC 403



 Score =  200 bits (508), Expect = 7e-51
 Identities = 124/372 (33%), Positives = 165/372 (44%), Gaps = 60/372 (16%)

Query: 373 LRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQA 432
           LRL  G  RCAG +EV      G VCD GW L++A V CR+LGCG AL           A
Sbjct: 198 LRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGA 257

Query: 433 TNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP-RLVGGDIPCSGRV 491
              W+    C G E +L DC    WG   CDH E+A + C+      RL  G   C+GR+
Sbjct: 258 GPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPRLRLADGPHGCAGRL 317

Query: 492 EVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQ----- 546
           EV HG  WGS+CD  + L  A+V CREL CG  ++  GGA FGEG+G I  ++ +     
Sbjct: 318 EVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNE 377

Query: 547 ---------------CEGHESHLSLC---------PVAPRPEGTCSH----SRDVGVVCS 578
                          C   E   ++C         P AP      +     SR    + S
Sbjct: 378 TALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTS 437

Query: 579 RYT-------------------------EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWD 613
           +                           ++RLV G + C GR+E+     WG++C+  WD
Sbjct: 438 QAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWD 497

Query: 614 IEDAHVLCQQLKCGVALST-PGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLC 672
           + D+ V+C++L CG      P   RFG G G IW     C GTE  + DCP    G   C
Sbjct: 498 MRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNC 557

Query: 673 PSEQVASVICSG 684
              +   V C+G
Sbjct: 558 AHNEDVGVTCTG 569



 Score =  166 bits (419), Expect = 1e-40
 Identities = 98/270 (36%), Positives = 136/270 (50%), Gaps = 56/270 (20%)

Query: 46  GTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWAN 105
           G    LRL DG + C+GR+EV     WG+VC++ W +   +V C +LGC  A+ APG A 
Sbjct: 299 GPAPRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAF 358

Query: 106 SSAGSGRIWMDHVSCRGNESAL-------W---DCKH--------DGWG----------K 137
              GSG I +D + CRGNE+AL       W   DC H        DG             
Sbjct: 359 FGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTD 418

Query: 138 HSNCTHQQ---------------DAGVTCSDGS------------NLEMRLTRGGNMCSG 170
            +N T ++                AGV+    S            + ++RL  G + CSG
Sbjct: 419 SNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSG 478

Query: 171 RIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFS-GSSNFGEGSGPIWFDDLICN 229
           R+E+    RWGTVCDD++++  ++V+CR+L CG        +  FG G+GPIW DD+ C 
Sbjct: 479 RLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCV 538

Query: 230 GNESALWNCKHQGWGKHNCDHAEDAGVICS 259
           G E++L +C    WGKHNC H ED GV C+
Sbjct: 539 GTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568



 Score =  141 bits (355), Expect = 4e-33
 Identities = 67/160 (41%), Positives = 89/160 (55%), Gaps = 3/160 (1%)

Query: 664 VTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG--QLRL 721
           +T  G     SE     I   +   +      S   P  P  P  S     ESG  ++RL
Sbjct: 716 LTTQGPQEMTSESTIKSIPQASLEPSAEIPEGSPESPKDPA-PSPSVSTTGESGLFRVRL 774

Query: 722 VNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPI 781
            +G  RCAGR+E++H G WGT+CDD+WDL DA V C +LGCG+     G  H+G GTGPI
Sbjct: 775 ADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGTGPI 834

Query: 782 WLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEF 821
           WLD+M C G E+ +  C S  WG+ NC H+ED G+ C+ +
Sbjct: 835 WLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGY 874



 Score =  140 bits (353), Expect = 7e-33
 Identities = 59/125 (47%), Positives = 81/125 (64%), Gaps = 3/125 (2%)

Query: 908  SPWEKRLASPSEETWITCDN---KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQ 964
            SP   +  +PS     T ++   ++RL +GP  C+GR+E+WH G WGTVCDD+WDL DA 
Sbjct: 748  SPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDAT 807

Query: 965  VVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDA 1024
            V C +LGCG       +  +G GTGPIWL+++ CKG+E+SL DCP+  WG   C H+ED 
Sbjct: 808  VACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDV 867

Query: 1025 AVNCT 1029
             + CT
Sbjct: 868  GLTCT 872



 Score =  137 bits (346), Expect = 4e-32
 Identities = 60/115 (52%), Positives = 76/115 (66%)

Query: 928  KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQG 987
            ++RL +GP  C+GR+E+WHGG WGTVCDD WDL DA V C+QLGCG AL A   A FG+G
Sbjct: 19   RLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEG 78

Query: 988  TGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATT 1042
             GP+WL+E+ C+GNE  L  C  R W    C H+EDA V C    V  +   +T+
Sbjct: 79   AGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTS 133



 Score =  124 bits (312), Expect = 4e-28
 Identities = 52/114 (45%), Positives = 73/114 (64%)

Query: 150 TCSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFS 209
           T  +     +RL  G N C+GR+E+   GRWGTVCDDN+++  A+V C +L CG      
Sbjct: 763 TTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV 822

Query: 210 GSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGAD 263
           G +++G G+GPIW DD+ C G+E++L +C    WGKHNCDH ED G+ C+   D
Sbjct: 823 GKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTD 876



 Score =  119 bits (299), Expect = 1e-26
 Identities = 50/107 (46%), Positives = 66/107 (61%)

Query: 266 LRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGF 325
           +RL DG   C+GRLEV   G WGT+CDD WD  DA VAC +LGC      +G+ +   G 
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831

Query: 326 GHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLE 372
           G IWLD + C+G E ++  C    WGKH C+H ED G+TC+  +D +
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYD 878



 Score =  114 bits (284), Expect = 7e-25
 Identities = 53/117 (45%), Positives = 73/117 (62%), Gaps = 2/117 (1%)

Query: 37  ACFVTSSLGGTDKE-LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCP 95
           AC + + +G    E LRL DG + C+GR+EV     WGTVC++GW +   +V C QLGC 
Sbjct: 5   ACLLAALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCG 64

Query: 96  TAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152
            A+ APG A    G+G +W+  ++CRGNE  L  C H GW  H  C+H++DAGV C+
Sbjct: 65  GALAAPGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHI-CSHEEDAGVVCA 120



 Score =  110 bits (275), Expect = 7e-24
 Identities = 55/110 (50%), Positives = 65/110 (59%), Gaps = 5/110 (4%)

Query: 266 LRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGC---PTAVTAIGRVNAS 322
           LRLV G ++CSGRLEV     WGT+CDD WD  D+AV C++LGC        A GR    
Sbjct: 467 LRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRF--G 524

Query: 323 KGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLE 372
            G G IWLD V C G E ++  C    WGKH C HNED GVTC+    L+
Sbjct: 525 WGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLD 574



 Score =  106 bits (265), Expect = 1e-22
 Identities = 50/110 (45%), Positives = 67/110 (60%), Gaps = 2/110 (1%)

Query: 50  ELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKA-PGWANSSA 108
           +LRLV G +KCSGR+EV   + WGTVC++ W M   +V+C +LGC    +  P       
Sbjct: 466 QLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGW 525

Query: 109 GSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLE 158
           G+G IW+D V C G E++L DC    WGKH NC H +D GVTC+    L+
Sbjct: 526 GAGPIWLDDVGCVGTEASLSDCPAAPWGKH-NCAHNEDVGVTCTGPPGLD 574



 Score =  106 bits (264), Expect = 1e-22
 Identities = 44/102 (43%), Positives = 65/102 (63%), Gaps = 1/102 (0%)

Query: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
           +RL DG N+C+GR+EV     WGTVC++ W +   +V C +LGC       G  +   G+
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831

Query: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152
           G IW+D + C+G+E++L DC    WGKH NC H++D G+TC+
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKH-NCDHEEDVGLTCT 872



 Score =  100 bits (249), Expect = 8e-21
 Identities = 44/104 (42%), Positives = 61/104 (58%)

Query: 479 RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNG 538
           RL  G   C+GR+EV H   WG++CD ++ L  A+V C EL CG V   +G  H+G G G
Sbjct: 773 RLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGTG 832

Query: 539 QIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE 582
            IW ++  C+G E+ LS CP     +  C H  DVG+ C+ YT+
Sbjct: 833 PIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTD 876



 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 48/137 (35%), Positives = 66/137 (48%), Gaps = 7/137 (5%)

Query: 555 SLCPVAPRPEGTCSHSRDVGVVCSRYT-------EIRLVNGKTPCEGRVELKTLGAWGSL 607
           SL P A  PEG+    +D     S  T        +RL +G   C GR+E+   G WG++
Sbjct: 737 SLEPSAEIPEGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTV 796

Query: 608 CNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTAL 667
           C+ +WD+ DA V C +L CG      G   +G G G IW     C G+E  + DCP  A 
Sbjct: 797 CDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAW 856

Query: 668 GASLCPSEQVASVICSG 684
           G   C  E+   + C+G
Sbjct: 857 GKHNCDHEEDVGLTCTG 873



 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 40/114 (35%), Positives = 56/114 (49%)

Query: 364 TCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTS 423
           T  +     +RL  G +RCAG +EV      G VCD  W L++A V C +LGCG      
Sbjct: 763 TTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV 822

Query: 424 YQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHRE 477
            + +        WL    C G+E SL DC +  WG   CDH E+  +TC+ + +
Sbjct: 823 GKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTD 876



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 10/111 (9%)

Query: 819 SEFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPA 878
           S    +RL    +R  CAGRLEV++ G WGTV   +       V C +LGC   GK+ P 
Sbjct: 767 SGLFRVRLADGPNR--CAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGC---GKVRP- 820

Query: 879 SLDKAM----SIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC 925
            + K      + P+W+D++ C     +L  CPS  W K      E+  +TC
Sbjct: 821 RVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTC 871


>gi|18152779 scavenger receptor cysteine rich domain containing,
           group B (4 domains) [Homo sapiens]
          Length = 575

 Score =  338 bits (866), Expect = 2e-92
 Identities = 192/541 (35%), Positives = 258/541 (47%), Gaps = 95/541 (17%)

Query: 26  PFTITVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAV 85
           P  ++ +LLL             +ELRLV G ++C GR+EV     WG+VC++ W +   
Sbjct: 33  PQALSFLLLLPLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDA 92

Query: 86  SVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQ 145
           +V+C QLGC  A+  P       G G I +D+V CRG E+AL +C   GWG H NC H +
Sbjct: 93  NVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVH-NCFHYE 151

Query: 146 DAGVTCSD------------------------GSNLEMRLTRGGNMCSGRIEIKFQGRWG 181
           D  V C +                         S   +RL  G N+C GR+EI   G WG
Sbjct: 152 DVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWG 211

Query: 182 TVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQ 241
           TVCDD++ +  A+V+CRQL CG+A++ + ++ FG G+G I  D++ C G E  L  C+  
Sbjct: 212 TVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSL 271

Query: 242 GWGKHNCDHAEDAGVICSKGADLSL----------------------------------- 266
           GWG HNC H EDAG +C+     +L                                   
Sbjct: 272 GWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLT 331

Query: 267 -------------RLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAV 313
                        RLV G   C GR+EV   G WGT+CDD WD  DA VAC++ GC  A+
Sbjct: 332 TAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPAL 391

Query: 314 TAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS------- 366
            A G  +   G G + LD+V C G E  +  C H  WG+H C H+EDAG  C+       
Sbjct: 392 GATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGL 451

Query: 367 ----DGS-----------DLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVC 411
               DGS           D  LRL  G  RC G VE+ + +  G VCD  W L+ A V+C
Sbjct: 452 QVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLC 511

Query: 412 RQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKIT 471
           RQLGCG AL    + +         L    C G E++L  C + +W    CDH E+A + 
Sbjct: 512 RQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVL 571

Query: 472 C 472
           C
Sbjct: 572 C 572



 Score =  332 bits (851), Expect = 1e-90
 Identities = 193/523 (36%), Positives = 238/523 (45%), Gaps = 83/523 (15%)

Query: 372 ELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQ 431
           ELRL GG SRC G +EV      G VCD  W + +A+VVCRQLGCG AL     +     
Sbjct: 57  ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116

Query: 432 ATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS-------------AHREP 478
                L    C G E +L +C +  WG   C HYE+  + C                R P
Sbjct: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176

Query: 479 -------------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVV 525
                        RLVGG   C GRVE+ H   WG++CD D+ L  A+V+CR+L CG  +
Sbjct: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236

Query: 526 SILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC-------- 577
           +    A FG G G I  +   CEG E  L+ C         C H  D G +C        
Sbjct: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296

Query: 578 ---------------------------SRYT---------------EIRLVNGKTPCEGR 595
                                      SR T                +RLV G  PC GR
Sbjct: 297 TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356

Query: 596 VELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGT 655
           VE+   G WG++C+  WD  DA V C++  CG AL   G   FG G G +      C GT
Sbjct: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416

Query: 656 EQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIE 715
           E  + DC     G   C   + A  +C+G +   L      S   TR   P         
Sbjct: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGS-ETTRVPTPRP------R 469

Query: 716 SGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFG 775
            G LRLVNG  RC GRVE+Y    WGT+CDD+WDL  A V+CRQLGCG+A+ A G AHFG
Sbjct: 470 DGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFG 529

Query: 776 EGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVIC 818
            G GPI LD +KC G+ES +  C    W   NC H EDA V+C
Sbjct: 530 PGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  327 bits (839), Expect = 3e-89
 Identities = 195/526 (37%), Positives = 241/526 (45%), Gaps = 85/526 (16%)

Query: 580  YTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
            + E+RLV G + C GR+E+   G+WGS+C+  WD+ DA+V+C+QL CG+AL  P    FG
Sbjct: 55   FQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFG 114

Query: 640  KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICS---GNQSQTLSSCNSS 696
            +G G I      C G E  + +C     G   C   +  +V+C      Q  T     S 
Sbjct: 115  QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSR 174

Query: 697  SLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVV 756
            +   T P    E        G +RLV G   C GRVEI H G WGT+CDD W L DA VV
Sbjct: 175  APPTTLPNGKSE--------GSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVV 226

Query: 757  CRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGV 816
            CRQLGCG A+ AT +A FG GTG I LD + C G E R+  C S GWG  NC H EDAG 
Sbjct: 227  CRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGA 286

Query: 817  ICSEFMSLRLT---SEASRE---------------------------------------- 833
            +C+      LT   S A+RE                                        
Sbjct: 287  LCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRL 346

Query: 834  -----ACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPM 888
                  C GR+EV + G WGTV           V CR+ GC                 P+
Sbjct: 347  VGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPV 406

Query: 889  WVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC----------------------- 925
             +DNV C      L  C    W +      E+    C                       
Sbjct: 407  LLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTP 466

Query: 926  ---DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEA 982
               D  +RL  G   C GRVE++ G  WGTVCDD+WDL  A V+C+QLGCG AL A  EA
Sbjct: 467  RPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEA 526

Query: 983  EFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
             FG G GPI L+ VKC+G ES+L  C   RW    C H EDA+V C
Sbjct: 527  HFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  326 bits (836), Expect = 7e-89
 Identities = 181/517 (35%), Positives = 247/517 (47%), Gaps = 67/517 (12%)

Query: 476 REPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGE 535
           +E RLVGG   C GR+EV HG +WGS+CD D+ +  A+V+CR+L CG  + +     FG+
Sbjct: 56  QELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQ 115

Query: 536 GNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYT-------------- 581
           G G I  +  +C G E+ LS C         C H  DV V+C  +               
Sbjct: 116 GRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRA 175

Query: 582 ------------EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVA 629
                        +RLV G   C+GRVE+   G WG++C+  W + DA V+C+QL CG A
Sbjct: 176 PPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAA 235

Query: 630 LSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
           ++    A FG G G I     HC G E  +  C     G   C   + A  +C+G    T
Sbjct: 236 MAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPT 295

Query: 690 LSSCNSSSLG-----------------PTRPTIPEESAV--ACIESGQLRLVNGGGRCAG 730
           L++  SS+                   P+R T    +A   A  +SG+LRLV G G C G
Sbjct: 296 LTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRG 355

Query: 731 RVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790
           RVE+ H G WGT+CDD WD +DA V CR+ GCG A+ ATG  HFG G GP+ LD + C G
Sbjct: 356 RVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAG 415

Query: 791 KESRIWQCHSHGWGQQNCRHKEDAGVICS--EFMSLRLTSEASR---------------- 832
            E+R+  C   GWGQ NC H EDAG +C+  E + L++  + S                 
Sbjct: 416 TEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRL 475

Query: 833 ----EACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPM 888
                 C GR+E++    WGTV   +      GV+CRQLGC         +       P+
Sbjct: 476 VNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPI 535

Query: 889 WVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC 925
            +DNV+C      L  C    W+      SE+  + C
Sbjct: 536 LLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  314 bits (805), Expect = 3e-85
 Identities = 183/516 (35%), Positives = 234/516 (45%), Gaps = 96/516 (18%)

Query: 158 EMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEG 217
           E+RL  G + C GR+E+   G WG+VCDD++++  A+V+CRQL CG A+       FG+G
Sbjct: 57  ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116

Query: 218 SGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSK----------------- 260
            GPI  D++ C G E+AL  C  +GWG HNC H ED  V+C +                 
Sbjct: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176

Query: 261 -------GADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAV 313
                   ++ S+RLV G   C GR+E+   G WGT+CDD W   DAAV C+QLGC  A+
Sbjct: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236

Query: 314 TAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLEL 373
            A        G GHI LD+V C+G EP +  C+   WG H C H+EDAG  C+      L
Sbjct: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296

Query: 374 ----------------------------------------------RLR--GGGSRCAGT 385
                                                         RLR  GG   C G 
Sbjct: 297 TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356

Query: 386 VEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGN 445
           VEV      G VCD  W   +A V CR+ GCG AL  +   +         L    C G 
Sbjct: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416

Query: 446 ETSLWDCKNWQWGGLTCDHYEEAKITCSAHRE------------------------PRLV 481
           E  L DC +  WG   C H+E+A   C+   E                         RLV
Sbjct: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLV 476

Query: 482 GGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIW 541
            G   C GRVE+  G  WG++CD  + L AA VLCR+L CG  ++  G AHFG G G I 
Sbjct: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536

Query: 542 AEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC 577
            +  +C G ES L LC         C HS D  V+C
Sbjct: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  159 bits (401), Expect = 2e-38
 Identities = 98/268 (36%), Positives = 122/268 (45%), Gaps = 35/268 (13%)

Query: 821  FMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKI-NPAS 879
            F  LRL    SR  C GRLEV + G+WG+V           VVCRQLGC     +  P +
Sbjct: 55   FQELRLVGGPSR--CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLA 112

Query: 880  LDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN------------ 927
              +    P+ +DNV+C      L +C S  W        E+  + CD             
Sbjct: 113  FGQGRG-PILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKML 171

Query: 928  ----------------KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLG 971
                             +RL  G   C GRVEI H G WGTVCDD W L DA VVC+QLG
Sbjct: 172  TSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLG 231

Query: 972  CGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDI 1031
            CG A+ A   A FG GTG I L+ V C+G E  L  C +  WG   CGH EDA   C  +
Sbjct: 232  CGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGL 291

Query: 1032 ---SVQKTPQKATTGRSSRQSSFIAVGI 1056
               ++   P  AT    + Q+   A G+
Sbjct: 292  GPPTLTALPSSATREDWAWQTDPSATGV 319


>gi|4506143 neurotrypsin precursor [Homo sapiens]
          Length = 875

 Score =  329 bits (843), Expect = 1e-89
 Identities = 190/499 (38%), Positives = 247/499 (49%), Gaps = 50/499 (10%)

Query: 572  DVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCG---V 628
            D G    R+  +RL  GK   EG VE+   G WG++C+SHWD  DA V+C QL+ G   +
Sbjct: 159  DWGYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGI 218

Query: 629  ALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQ 688
            A  TP     G G   I+     C G E+++  C        +CP +  A+V CS     
Sbjct: 219  AKQTPFS---GLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCS----- 270

Query: 689  TLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSW 748
                    S GPT P I              RL  G     GRVE+YH G WGT+CDD W
Sbjct: 271  -------FSHGPTFPII--------------RLAGGSSVHEGRVELYHAGQWGTVCDDQW 309

Query: 749  DLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNC 808
            D +DA V+CRQLG      A   A+FGEG+GP+ LDE++C G E  I QC    WG+ NC
Sbjct: 310  DDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNC 369

Query: 809  RHKEDAGVICSEFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLG 868
             HKEDAGV C+      +     + +  GRLEV+Y G WGTV     +E    VVCRQLG
Sbjct: 370  GHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLG 429

Query: 869  CADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC--- 925
                GK   A+  +  + P+W+D+V C        QC    W +   S  E+  I C   
Sbjct: 430  -FKYGKQASANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPG 488

Query: 926  --------DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALK 977
                       +RL +G     GRVE++  G WGT+CDD W   DA V+C+QLG     +
Sbjct: 489  GEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPAR 548

Query: 978  AFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTP 1037
            A   A FG+G GPI ++ VKC GNE SL DC  +  G   C H EDA V C         
Sbjct: 549  ARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFG----- 603

Query: 1038 QKATTGRSSRQSSFIAVGI 1056
             K  +G S+++S     G+
Sbjct: 604  -KKASGNSNKESLSSVCGL 621



 Score =  299 bits (765), Expect = 1e-80
 Identities = 165/432 (38%), Positives = 218/432 (50%), Gaps = 12/432 (2%)

Query: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
           +RL  G+N+  G VEV     WGTVC++ W     SVIC+QL       A     S  G 
Sbjct: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229

Query: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLE---MRLTRGGNM 167
             I+  +V CRG+E  +  C+ D W +   C  +  A VTCS         +RL  G ++
Sbjct: 230 IPIYWSNVRCRGDEENILLCEKDIW-QGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSV 288

Query: 168 CSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLI 227
             GR+E+   G+WGTVCDD ++   A VICRQL           + FGEGSGP+  D++ 
Sbjct: 289 HEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVR 348

Query: 228 CNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEW 287
           C GNE ++  C    WG+HNC H EDAGV C+   D  +RL  G     GRLEV ++G+W
Sbjct: 349 CTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQW 408

Query: 288 GTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKH 347
           GT+CDDGW   +  V C+QLG      A    +  +  G IWLD VSC G E    QC  
Sbjct: 409 GTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSR 467

Query: 348 HEWGKHYCNHNEDAGVTCSDGSD-------LELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400
            +WG+H C+H ED  + C  G +         +RL  G ++  G VEV I    G +CD 
Sbjct: 468 RQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDD 527

Query: 401 GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGL 460
           GW  K+A V+CRQLG     +     Y         +    C GNE SL DC     G  
Sbjct: 528 GWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRH 587

Query: 461 TCDHYEEAKITC 472
            C H E+A + C
Sbjct: 588 NCRHSEDAGVIC 599



 Score =  274 bits (700), Expect = 4e-73
 Identities = 168/483 (34%), Positives = 226/483 (46%), Gaps = 49/483 (10%)

Query: 349 EWGKHYCNHNEDAGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEAD 408
           +WG  YC+        C  GS   +RLRGG +   GTVEV    + G VC   W   +A 
Sbjct: 159 DWG--YCD--------CRHGS---VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDAS 205

Query: 409 VVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEA 468
           V+C QL  G         +S +     +     C G+E ++  C+   W G  C     A
Sbjct: 206 VICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAA 265

Query: 469 KITCSAHREP-----RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGT 523
            +TCS    P     RL GG     GRVE+ H   WG++CD  +    A V+CR+L    
Sbjct: 266 AVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG 325

Query: 524 VVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE- 582
           +      A+FGEG+G +  +E +C G+E  +  CP +   E  C H  D GV C+  T+ 
Sbjct: 326 IAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDG 385

Query: 583 -IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQL--KCGVALSTPGGARFG 639
            IRL  GK   EGR+E+   G WG++C+  W   + +V+C+QL  K G   S      F 
Sbjct: 386 VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQAS---ANHFE 442

Query: 640 KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVIC-SGNQSQTLSSCNSSSL 698
           +  G IW     C+G E     C     G   C   +  S+ C  G +   L      SL
Sbjct: 443 ESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRL------SL 496

Query: 699 GPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR 758
           G                   +RL++G  +  GRVE++  G WGTICDD W   DA V+CR
Sbjct: 497 G-----------------FPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICR 539

Query: 759 QLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVIC 818
           QLG      A   A+FGEG GPI +D +KC G E  +  C     G+ NCRH EDAGVIC
Sbjct: 540 QLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599

Query: 819 SEF 821
             F
Sbjct: 600 DYF 602



 Score =  266 bits (680), Expect = 8e-71
 Identities = 139/340 (40%), Positives = 192/340 (56%), Gaps = 11/340 (3%)

Query: 34  LLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLG 93
           + +A   + S G T   +RL  G +   GRVE+    +WGTVC++ W      VIC QLG
Sbjct: 263 MAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLG 322

Query: 94  CPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSD 153
                KA   A    GSG + +D V C GNE ++  C    WG+H NC H++DAGV+C+ 
Sbjct: 323 LSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEH-NCGHKEDAGVSCTP 381

Query: 154 GSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSN 213
            ++  +RL  G     GR+E+ ++G+WGTVCDD +   +  V+CRQL  G       S+N
Sbjct: 382 LTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQL--GFKYGKQASAN 439

Query: 214 -FGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGAD---LSL--- 266
            F E +GPIW DD+ C+G E+    C  + WG+H+C H ED  + C  G +   LSL   
Sbjct: 440 HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFP 499

Query: 267 -RLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGF 325
            RL+DG  +  GR+EV   G+WGTICDDGW   DAAV C+QLG      A       +G 
Sbjct: 500 VRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGK 559

Query: 326 GHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTC 365
           G I +D+V C G+E ++  C   + G+H C H+EDAGV C
Sbjct: 560 GPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599



 Score =  232 bits (591), Expect = 2e-60
 Identities = 164/540 (30%), Positives = 228/540 (42%), Gaps = 51/540 (9%)

Query: 243 WGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAV 302
           WG  +C H              S+RL  G  E  G +EV   G WGT+C   WD  DA+V
Sbjct: 160 WGYCDCRHG-------------SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASV 206

Query: 303 ACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAG 362
            C QL       A     +  G   I+  +V C+G E  +  C+   W    C     A 
Sbjct: 207 ICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAA 266

Query: 363 VTCSDGSDLE---LRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSA 419
           VTCS         +RL GG S   G VE+      G VCD  W   +A+V+CRQLG    
Sbjct: 267 VTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326

Query: 420 LKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP- 478
            K  +Q Y    +    L    C GNE S+  C    WG   C H E+A ++C+   +  
Sbjct: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGV 386

Query: 479 -RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCREL--QCGTVVSILGGAHFGE 535
            RL GG     GR+EV +   WG++CD  ++     V+CR+L  + G   S     HF E
Sbjct: 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQAS---ANHFEE 443

Query: 536 GNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC---------SRYTEIRLV 586
             G IW ++  C G E+    C         CSH  DV + C         S    +RL+
Sbjct: 444 STGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLM 503

Query: 587 NGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIW 646
           +G+   EGRVE+   G WG++C+  W  +DA V+C+QL           A FG+G G I 
Sbjct: 504 DGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIH 563

Query: 647 RHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIP 706
                CTG E+ + DC    +G   C   + A VIC     +   + N  SL        
Sbjct: 564 VDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSV----- 618

Query: 707 EESAVACIESGQLRLVNGGGRCAG----RVEIYHEGSWG--------TICDDSWDLSDAH 754
               +  +   Q R++ G     G    +V +  + S G        T+    W L+ AH
Sbjct: 619 --CGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAH 676


>gi|5174411 CD5 molecule-like [Homo sapiens]
          Length = 347

 Score =  260 bits (665), Expect = 4e-69
 Identities = 137/350 (39%), Positives = 192/350 (54%), Gaps = 26/350 (7%)

Query: 33  LLLSAC----FVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVI 88
           L+L+ C    F+ S  G     +RLV G ++C GRVEV+ + +WGTVC++GW ++ V+V+
Sbjct: 7   LILAICTRPGFLASPSG-----VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVL 61

Query: 89  CNQLGCPTAIKAPG---WANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQ 145
           C +LGC  A   P    +   +    ++ +  VSC G E  L  C+ +   +  +C+H +
Sbjct: 62  CRELGCGAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQE---EVYDCSHDE 118

Query: 146 DAGVTCSDGSNL------EMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQ 199
           DAG +C +  +        +RL  G   C GR+E+K Q +W TVC   +++  A V+CRQ
Sbjct: 119 DAGASCENPESSFSPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQ 178

Query: 200 LECGSAVSFSGSSN-FGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVIC 258
           L CG AV      N    G  PIW   + C+G E+ L +C    WGK+ C+H ED  V C
Sbjct: 179 LGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC 238

Query: 259 SKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGR 318
               D  LRLV G   CSGRLEV  +G WG++CDD W   +  V CKQLGC  +++   R
Sbjct: 239 EDPFD--LRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFR 296

Query: 319 VNA--SKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS 366
                  G G IWLD+V C G E ++ QC+H  WG H C H ED  V CS
Sbjct: 297 DRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346



 Score =  244 bits (622), Expect = 4e-64
 Identities = 129/328 (39%), Positives = 177/328 (53%), Gaps = 22/328 (6%)

Query: 719  LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHF---G 775
            +RLV G  RC GRVE+  +G WGT+CDD WD+ D  V+CR+LGCG A        +    
Sbjct: 24   VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83

Query: 776  EGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVIC-SEFMSLRLTSEASREA 834
            E    + +  + C G E  + QC        +C H EDAG  C +   S     E  R A
Sbjct: 84   EKEQKVLIQSVSCTGTEDTLAQCEQE--EVYDCSHDEDAGASCENPESSFSPVPEGVRLA 141

Query: 835  -----CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCA----DKGKINPASLDKAMS 885
                 C GR+EV +   W TV ++  S     VVCRQLGC      + + N  +  +   
Sbjct: 142  DGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRK-- 199

Query: 886  IPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN--KIRLQEGPTSCSGRVE 943
             P+W+  + C     TL  CPS PW K   +  E+TW+ C++   +RL  G   CSGR+E
Sbjct: 200  -PIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSGRLE 258

Query: 944  IWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALK-AFKEAE-FGQGTGPIWLNEVKCKGN 1001
            + H G WG+VCDD+W   + QVVC+QLGCG +L  +F++ + +G G G IWL+ V+C G 
Sbjct: 259  VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGE 318

Query: 1002 ESSLWDCPARRWGHSECGHKEDAAVNCT 1029
            E SL  C  R WG  +C H+ED AV C+
Sbjct: 319  EQSLEQCQHRFWGFHDCTHQEDVAVICS 346



 Score =  236 bits (602), Expect = 9e-62
 Identities = 130/338 (38%), Positives = 180/338 (53%), Gaps = 18/338 (5%)

Query: 257 ICSKGADLS----LRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTA 312
           IC++   L+    +RLV G+  C GR+EV  +G+WGT+CDDGWD  D AV C++LGC  A
Sbjct: 11  ICTRPGFLASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAA 70

Query: 313 V---TAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGS 369
               + I     ++    + + SVSC G E  + QC+  E   + C+H+EDAG +C +  
Sbjct: 71  SGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPE 128

Query: 370 DL------ELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTS 423
                    +RL  G   C G VEV+ Q     VC  GW L+ A VVCRQLGCG A+ T 
Sbjct: 129 SSFSPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQ 188

Query: 424 YQVYSKIQATNT-WLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRLVG 482
            +           WL   SC+G E +L DC +  WG  TC+H E+  + C    + RLVG
Sbjct: 189 KRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVG 248

Query: 483 GDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVV--SILGGAHFGEGNGQI 540
           GD  CSGR+EV H   WGS+CD ++  +   V+C++L CG  +  S      +G G G+I
Sbjct: 249 GDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRI 308

Query: 541 WAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS 578
           W +  +C G E  L  C         C+H  DV V+CS
Sbjct: 309 WLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346



 Score =  217 bits (552), Expect = 6e-56
 Identities = 119/355 (33%), Positives = 173/355 (48%), Gaps = 47/355 (13%)

Query: 479 RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHF---GE 535
           RLVGG   C GRVEV+    WG++CD  + ++  +VLCREL CG       G  +    E
Sbjct: 25  RLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAE 84

Query: 536 GNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE--------IRLVN 587
              ++  +   C G E  L+ C      +  CSH  D G  C             +RL +
Sbjct: 85  KEQKVLIQSVSCTGTEDTLAQCEQEEVYD--CSHDEDAGASCENPESSFSPVPEGVRLAD 142

Query: 588 GKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGA-RFGKGNGQIW 646
           G   C+GRVE+K    W ++C + W +  A V+C+QL CG A+ T     +   G   IW
Sbjct: 143 GPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPIW 202

Query: 647 RHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIP 706
                C+G E  + DCP    G +                     +CN            
Sbjct: 203 LSQMSCSGREATLQDCPSGPWGKN---------------------TCNHD---------- 231

Query: 707 EESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAI 766
           E++ V C +   LRLV G   C+GR+E+ H+G WG++CDD+W   +  VVC+QLGCG+++
Sbjct: 232 EDTWVECEDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL 291

Query: 767 NAT--GSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
           + +      +G G G IWLD ++C+G+E  + QC    WG  +C H+ED  VICS
Sbjct: 292 SPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346



 Score =  210 bits (534), Expect = 7e-54
 Identities = 121/326 (37%), Positives = 165/326 (50%), Gaps = 16/326 (4%)

Query: 373 LRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQA 432
           +RL GG  RC G VEVE +   G VCD GW +K+  V+CR+LGCG+A  T   +  +  A
Sbjct: 24  VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83

Query: 433 TNTWLFLS---SCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP--------RLV 481
                 L    SC G E +L  C+  Q     C H E+A  +C              RL 
Sbjct: 84  EKEQKVLIQSVSCTGTEDTLAQCE--QEEVYDCSHDEDAGASCENPESSFSPVPEGVRLA 141

Query: 482 GGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAH-FGEGNGQI 540
            G   C GRVEVKH + W ++C + +SL AA V+CR+L CG  V      +    G   I
Sbjct: 142 DGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPI 201

Query: 541 WAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKT 600
           W  +  C G E+ L  CP  P  + TC+H  D  V C    ++RLV G   C GR+E+  
Sbjct: 202 WLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSGRLEVLH 261

Query: 601 LGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGAR--FGKGNGQIWRHMFHCTGTEQH 658
            G WGS+C+ +W  ++  V+C+QL CG +LS     R  +G G G+IW     C+G EQ 
Sbjct: 262 KGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQS 321

Query: 659 MGDCPVTALGASLCPSEQVASVICSG 684
           +  C     G   C  ++  +VICSG
Sbjct: 322 LEQCQHRFWGFHDCTHQEDVAVICSG 347



 Score =  142 bits (359), Expect = 1e-33
 Identities = 79/212 (37%), Positives = 104/212 (49%), Gaps = 20/212 (9%)

Query: 835  CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCA-----DKGKINPASLDKAMSIPMW 889
            C GR+EV   G WGTV         V V+CR+LGC        G +     +K   +   
Sbjct: 33   CEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKV--L 90

Query: 890  VDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDNK----------IRLQEGPTSCS 939
            + +V C    DTL QC     E    S  E+   +C+N           +RL +GP  C 
Sbjct: 91   IQSVSCTGTEDTLAQCEQE--EVYDCSHDEDAGASCENPESSFSPVPEGVRLADGPGHCK 148

Query: 940  GRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEA-EFGQGTGPIWLNEVKC 998
            GRVE+ H   W TVC   W L  A+VVC+QLGCG A+   K   +   G  PIWL+++ C
Sbjct: 149  GRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSC 208

Query: 999  KGNESSLWDCPARRWGHSECGHKEDAAVNCTD 1030
             G E++L DCP+  WG + C H ED  V C D
Sbjct: 209  SGREATLQDCPSGPWGKNTCNHDEDTWVECED 240



 Score = 77.0 bits (188), Expect = 9e-14
 Identities = 43/118 (36%), Positives = 56/118 (47%), Gaps = 14/118 (11%)

Query: 914  LASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCG 973
            LASPS          +RL  G   C GRVE+   G WGTVCDD WD+ D  V+C++LGCG
Sbjct: 18   LASPSG---------VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCG 68

Query: 974  PALKAFKEAEF---GQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
             A        +    +    + +  V C G E +L  C        +C H EDA  +C
Sbjct: 69   AASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASC 124


>gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 343

 Score =  255 bits (651), Expect = 2e-67
 Identities = 115/235 (48%), Positives = 151/235 (64%), Gaps = 23/235 (9%)

Query: 155 SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNF 214
           S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++ + A+V+CRQL CG A+   G++ F
Sbjct: 14  SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF 73

Query: 215 GEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------------- 261
           G+GSGPI  DD+ C+GNES LW+C H GW  HNC H+EDAGVICS G             
Sbjct: 74  GQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPS 133

Query: 262 ----------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPT 311
                     + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C+QLGC  
Sbjct: 134 RFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGW 193

Query: 312 AVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS 366
           A +A G     +G G I LD V C GHE  +W C ++ W  H C H+EDAGV CS
Sbjct: 194 ATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248



 Score =  246 bits (629), Expect = 7e-65
 Identities = 118/245 (48%), Positives = 153/245 (62%), Gaps = 25/245 (10%)

Query: 39  FVTSSLGGTDK-ELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTA 97
           F+ S +G      LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A
Sbjct: 5   FLFSPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 64

Query: 98  IKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG--- 154
           + APG A    GSG I +D V C GNES LW C H+GW  H NC H +DAGV CS G   
Sbjct: 65  MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSH-NCGHSEDAGVICSGGPPR 123

Query: 155 --------------------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHAS 194
                               S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++ + A+
Sbjct: 124 TPIRPRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 183

Query: 195 VICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDA 254
           V+CRQL CG A S  G++ FG+GSGPI  DD+ C+G+ES LW+C + GW  HNC H EDA
Sbjct: 184 VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDA 243

Query: 255 GVICS 259
           GVICS
Sbjct: 244 GVICS 248



 Score =  246 bits (627), Expect = 1e-64
 Identities = 118/237 (49%), Positives = 155/237 (65%), Gaps = 6/237 (2%)

Query: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642
           +RLVNG   C+GRVE+   G+WG++C+  WD  DA+V+C+QL CG A+  PG ARFG+G+
Sbjct: 18  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 77

Query: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR 702
           G I      C+G E ++  CP     +  C   + A VICSG   +T     S       
Sbjct: 78  GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLC 137

Query: 703 PTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGC 762
             I  ES++A      LRLVNGG RC GRVE+ + GSWGT+CDDSWD +DA+VVCRQLGC
Sbjct: 138 SPIGPESSLA------LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 191

Query: 763 GEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
           G A +A G+A FG+G+GPI LD+++C+G ES +W C ++GW   NC H EDAGVICS
Sbjct: 192 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248



 Score =  204 bits (520), Expect = 3e-52
 Identities = 105/242 (43%), Positives = 134/242 (55%), Gaps = 27/242 (11%)

Query: 709 SAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINA 768
           S V    S  LRLVNGG RC GRVE+ + GSWGT+CDDSWD +DA+VVCRQLGCG A+ A
Sbjct: 8   SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 769 TGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS--------- 819
            G+A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS         
Sbjct: 68  PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 820 ----------------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVV 863
                             ++LRL +   R  C GR+EV Y G+WGTV   S       VV
Sbjct: 128 PRSWPSRFLCSPIGPESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTNDANVV 185

Query: 864 CRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWI 923
           CRQLGC         +     S P+ +D+V+C      LW CP++ W        E+  +
Sbjct: 186 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGV 245

Query: 924 TC 925
            C
Sbjct: 246 IC 247



 Score =  193 bits (490), Expect = 9e-49
 Identities = 101/237 (42%), Positives = 129/237 (54%), Gaps = 27/237 (11%)

Query: 262 ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNA 321
           + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C+QLGC  A+ A G    
Sbjct: 14  SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF 73

Query: 322 SKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDG------------- 368
            +G G I LD V C G+E  +W C H+ W  H C H+EDAGV CS G             
Sbjct: 74  GQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPS 133

Query: 369 ----------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGS 418
                     S L LRL  GG RC G VEV  +   G VCD  W   +A+VVCRQLGCG 
Sbjct: 134 RFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGW 193

Query: 419 ALKTSYQVYSKIQATNTWLFLSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCS 473
           A  TS    ++    +  + L    C+G+E+ LW C N  W    C H+E+A + CS
Sbjct: 194 A--TSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248



 Score =  181 bits (459), Expect = 3e-45
 Identities = 97/236 (41%), Positives = 122/236 (51%), Gaps = 31/236 (13%)

Query: 822  MSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLD 881
            ++LRL +   R  C GR+EV Y G+WGTV   S       VVCRQLGC     + P +  
Sbjct: 16   LALRLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG-WAMLAPGNAR 72

Query: 882  KAM-SIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN------------- 927
                S P+ +D+V+C      LW CP + W       SE+  + C               
Sbjct: 73   FGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWP 132

Query: 928  --------------KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCG 973
                           +RL  G   C GRVE+ + GSWGTVCDDSWD +DA VVC+QLGCG
Sbjct: 133  SRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG 192

Query: 974  PALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029
             A  A   A FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+
Sbjct: 193  WATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248



 Score =  177 bits (448), Expect = 6e-44
 Identities = 94/250 (37%), Positives = 130/250 (52%), Gaps = 34/250 (13%)

Query: 479 RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNG 538
           RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG  +   G A FG+G+G
Sbjct: 19  RLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSG 78

Query: 539 QIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS-------------------- 578
            I  ++ +C G+ES+L  CP        C HS D GV+CS                    
Sbjct: 79  PIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLCS 138

Query: 579 -----RYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTP 633
                    +RLVNG   C+GRVE+   G+WG++C+  WD  DA+V+C+QL CG A S P
Sbjct: 139 PIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAP 198

Query: 634 GGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSC 693
           G ARFG+G+G I      C+G E ++  CP     +  C   + A VICSG+ +      
Sbjct: 199 GNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGSWAVA---- 254

Query: 694 NSSSLGPTRP 703
                GP RP
Sbjct: 255 -----GPRRP 259


>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
          Length = 774

 Score =  213 bits (542), Expect = 8e-55
 Identities = 146/478 (30%), Positives = 221/478 (46%), Gaps = 84/478 (17%)

Query: 50  ELRLVDGENKCS-GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSA 108
           +LRL   + K S GRVEV    +WGTVC++ +S+ A  V+C +LG    ++A  W  SS+
Sbjct: 57  QLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGY---VEAKSWTASSS 113

Query: 109 ---GSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG----------- 154
              G G IW+D++ C GNE+ L  C  +GWG  ++C H +D GV CSD            
Sbjct: 114 YGKGEGPIWLDNLHCTGNEATLAACTSNGWGV-TDCKHTEDVGVVCSDKRIPGFKFDNSL 172

Query: 155 ----SNLEMRL------------TRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICR 198
                NL +++             +   +  G +E+K    W  +CD ++   ++ V+C 
Sbjct: 173 INQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVC- 231

Query: 199 QLECGSAVSFSGSSNF---------GEGSGPIWFDDLICNGNESALWNCK------HQGW 243
                    F G   +                W   + C G E+ + +CK          
Sbjct: 232 -----GMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPM 286

Query: 244 GKHNCDHAEDAGVICSKGADLS-----------------LRLVDGVTECSGRLEVRFQGE 286
               C++   A V C  G   S                 +RL  G     GR+EV   GE
Sbjct: 287 KNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGE 346

Query: 287 WGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCK 346
           WGT+CDD WD   A+V C++LG  +A  A+      +G G I L+ + C G+E ++  CK
Sbjct: 347 WGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCK 406

Query: 347 HHEWGKHYCNHNEDAGVTCSD---GSDLELRLRGGGSRCAGTVEVEIQR----LLGKVCD 399
            +   +  CNH EDAGV C+    G   +LRL GG +   G VEV ++R    + G VC 
Sbjct: 407 FNAESQG-CNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCG 465

Query: 400 RGWGLKEADVVCRQLGCG---SALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKN 454
           + WG+ EA VVCRQLG G   +A + ++  +  + +    +    C+G E SL  C++
Sbjct: 466 QNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRH 523



 Score =  207 bits (526), Expect = 6e-53
 Identities = 139/425 (32%), Positives = 190/425 (44%), Gaps = 58/425 (13%)

Query: 489 GRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCE 548
           GRVEV +   WG++CD DFS+ AA V+CREL      S    + +G+G G IW +   C 
Sbjct: 70  GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129

Query: 549 GHESHLSLCPVAPRPEGTCSHSRDVGVVCS----------------------RYTEIRL- 585
           G+E+ L+ C         C H+ DVGVVCS                      +  +IR+ 
Sbjct: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIR 189

Query: 586 -----VNGKTPC-EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
                   +TP  EG VE+K    W  +C+ HW  +++ V+C           PG   + 
Sbjct: 190 AILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMF------GFPGERTYN 243

Query: 640 ---------KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTL 690
                    +   + W     CTGTE H+  C +     SL P + V    C       +
Sbjct: 244 TKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQ-VSLDPMKNVT---CENGLPAVV 299

Query: 691 SSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDL 750
           S        P  P+   ++     E   +RL  G     GRVE+   G WGT+CDD WDL
Sbjct: 300 SCVPGQVFSPDGPSRFRKAYKP--EQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDL 357

Query: 751 SDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRH 810
             A VVCR+LG G A  A   +  G+G GPI L+E++C G E  I  C  +    Q C H
Sbjct: 358 VSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNH 416

Query: 811 KEDAGVICSE---FMSLRLTSEASREACAGRLEVFY--NGA--WGTVGKSSMSETTVGVV 863
           +EDAGV C+     +  +L     R    GR+EV    NG+  WG V   +       VV
Sbjct: 417 EEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVV 476

Query: 864 CRQLG 868
           CRQLG
Sbjct: 477 CRQLG 481



 Score =  204 bits (519), Expect = 4e-52
 Identities = 130/390 (33%), Positives = 173/390 (44%), Gaps = 71/390 (18%)

Query: 703  PTIPEESAVACIESGQLRLVNGGGRCA-GRVEIYHEGSWGTICDDSWDLSDAHVVCRQLG 761
            P   +  A A +   QLRL     + + GRVE+Y++G WGT+CDD + +  AHVVCR+LG
Sbjct: 42   PEYHQPQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELG 101

Query: 762  CGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSE- 820
              EA + T S+ +G+G GPIWLD + C G E+ +  C S+GWG  +C+H ED GV+CS+ 
Sbjct: 102  YVEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDK 161

Query: 821  --------------------------FMSLRLTSEASREACAGRLEVFYNGAWGTVGKSS 854
                                        ++  T         G +EV     W  +    
Sbjct: 162  RIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKH 221

Query: 855  MSETTVGVVCRQLGCADKGKINP------ASLDKAMSIPMWVD----------------- 891
             +     VVC   G   +   N       AS  K    P  +D                 
Sbjct: 222  WTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQV 281

Query: 892  ------NVQCPKGPDTLWQC-------PSSPWEKRLASPSEETWITCDNKIRLQEGPTSC 938
                  NV C  G   +  C       P  P   R A   E+        +RL+ G    
Sbjct: 282  SLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQP------LVRLRGGAYIG 335

Query: 939  SGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKC 998
             GRVE+   G WGTVCDD WDL  A VVC++LG G A +A   +  GQG GPI LNE++C
Sbjct: 336  EGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQC 395

Query: 999  KGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
             GNE S+ DC         C H+EDA V C
Sbjct: 396  TGNEKSIIDCKFNAESQG-CNHEEDAGVRC 424



 Score =  203 bits (517), Expect = 6e-52
 Identities = 153/492 (31%), Positives = 221/492 (44%), Gaps = 78/492 (15%)

Query: 170 GRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICN 229
           GR+E+ + G+WGTVCDD+F+I  A V+CR+L    A S++ SS++G+G GPIW D+L C 
Sbjct: 70  GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129

Query: 230 GNESALWNCKHQGWGKHNCDHAEDAGVICS----------------------KGADLSLR 267
           GNE+ L  C   GWG  +C H ED GV+CS                      +  D+ +R
Sbjct: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIR 189

Query: 268 LV-----DGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCP---TAVTAIGRV 319
            +            G +EV+    W  ICD  W + ++ V C   G P   T  T + ++
Sbjct: 190 AILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKM 249

Query: 320 NASKGFGHIWLDSVSCQGHEPAVWQCK------HHEWGKHYCNHNEDAGVTCSDGSDLE- 372
            AS+     W  S+ C G E  +  CK              C +   A V+C  G     
Sbjct: 250 FASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSP 309

Query: 373 ----------------LRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGC 416
                           +RLRGG     G VEV      G VCD  W L  A VVCR+LG 
Sbjct: 310 DGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGF 369

Query: 417 GSALK--TSYQVYSKIQATNTWLFLSSCNGNETSLWDCK-NWQWGGLTCDHYEEAKITCS 473
           GSA +  T  ++   I   +  L    C GNE S+ DCK N +  G  C+H E+A + C+
Sbjct: 370 GSAKEAVTGSRLGQGIGPIH--LNEIQCTGNEKSIIDCKFNAESQG--CNHEEDAGVRCN 425

Query: 474 A-----HREPRLVGGDIPCSGRVEV---KHGD-TWGSICDSDFSLEAASVLCRELQCGTV 524
                  ++ RL GG  P  GRVEV   ++G   WG +C  ++ +  A V+CR+L  G  
Sbjct: 426 TPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFA 485

Query: 525 VSILGGAHFGEG---NGQIWAEEFQCEGHESHLSLC----PVAPRPEGTCSHSRDVGVVC 577
            +      +  G   + ++     +C G E  L+ C         P+G   +    GV C
Sbjct: 486 SNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYG--AGVAC 543

Query: 578 SRYTEIRLVNGK 589
           S      ++N +
Sbjct: 544 SETAPDLVLNAE 555



 Score =  202 bits (514), Expect = 1e-51
 Identities = 149/493 (30%), Positives = 214/493 (43%), Gaps = 73/493 (14%)

Query: 262 ADLSLRLVDGVTECS-GRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVN 320
           A + LRL     + S GR+EV + G+WGT+CDD +  + A V C++LG   A +     +
Sbjct: 54  AKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSS 113

Query: 321 ASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDG------------ 368
             KG G IWLD++ C G+E  +  C  + WG   C H ED GV CSD             
Sbjct: 114 YGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLI 173

Query: 369 ----------SDLELRL-----RGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQ 413
                      D+ +R      R       G VEV+  +   ++CD+ W  K + VVC  
Sbjct: 174 NQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGM 233

Query: 414 LGCGSALKTSYQVYSKIQATNT---WLFLSSCNGNETSLWDCKNWQWGGL------TCDH 464
            G       + +VY    +      W F   C G E  +  CK      L      TC++
Sbjct: 234 FGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCEN 293

Query: 465 YEEAKITC-----------SAHREP--------RLVGGDIPCSGRVEVKHGDTWGSICDS 505
              A ++C           S  R+         RL GG     GRVEV     WG++CD 
Sbjct: 294 GLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDD 353

Query: 506 DFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEG 565
            + L +ASV+CREL  G+    + G+  G+G G I   E QC G+E  +  C      +G
Sbjct: 354 KWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQG 413

Query: 566 TCSHSRDVGVVCSR-----YTEIRLVNGKTPCEGRVELKTLG----AWGSLCNSHWDIED 616
            C+H  D GV C+        ++RL  G+ P EGRVE+         WG +C  +W I +
Sbjct: 414 -CNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVE 472

Query: 617 AHVLCQQLKCGVALSTPGGARFGKG---NGQIWRHMFHCTGTEQHMGDCPVTALGASLCP 673
           A V+C+QL  G A +      +  G   + ++      C+GTE  +  C       + CP
Sbjct: 473 AMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVA-CP 531

Query: 674 SEQV---ASVICS 683
              V   A V CS
Sbjct: 532 QGGVQYGAGVACS 544



 Score =  171 bits (434), Expect = 3e-42
 Identities = 151/522 (28%), Positives = 215/522 (41%), Gaps = 104/522 (19%)

Query: 371 LELRLRGGGSRCA-GTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALK-TSYQVYS 428
           ++LRL G   + + G VEV      G VCD  + +  A VVCR+LG   A   T+   Y 
Sbjct: 56  IQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYG 115

Query: 429 KIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP---------- 478
           K +    WL    C GNE +L  C +  WG   C H E+  + CS  R P          
Sbjct: 116 KGEGP-IWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLIN 174

Query: 479 -----RLVGGDIPC--------------SGRVEVKHGDTWGSICDSDFSLEAASVLCR-- 517
                 +   DI                 G VEVK G TW  ICD  ++ + + V+C   
Sbjct: 175 QIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMF 234

Query: 518 ----ELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPR------PEGTC 567
               E    T V  +  +   +   + W     C G E+H+S C + P+         TC
Sbjct: 235 GFPGERTYNTKVYKMFASRRKQ---RYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTC 291

Query: 568 SHSRDVGVVC-----------SRYTE--------IRLVNGKTPCEGRVELKTLGAWGSLC 608
            +     V C           SR+ +        +RL  G    EGRVE+   G WG++C
Sbjct: 292 ENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVC 351

Query: 609 NSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALG 668
           +  WD+  A V+C++L  G A     G+R G+G G I  +   CTG E+ + DC   A  
Sbjct: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAES 411

Query: 669 ASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRC 728
              C  E+ A V            CN+ ++G  +               +LRL  G    
Sbjct: 412 QG-CNHEEDAGV-----------RCNTPAMGLQK---------------KLRLNGGRNPY 444

Query: 729 AGRVEIYHEGS----WGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEG---TGPI 781
            GRVE+  E +    WG +C  +W + +A VVCRQLG G A NA     +  G   +  +
Sbjct: 445 EGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKV 504

Query: 782 WLDEMKCNGKESRIWQCHSHGWGQQNCRH---KEDAGVICSE 820
            +  +KC+G E  +  C  H      C     +  AGV CSE
Sbjct: 505 VMSGVKCSGTELSLAHCR-HDGEDVACPQGGVQYGAGVACSE 545



 Score =  155 bits (392), Expect = 2e-37
 Identities = 137/479 (28%), Positives = 197/479 (41%), Gaps = 66/479 (13%)

Query: 582  EIRLVNGKTP-CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGK 640
            ++RL   K    EGRVE+   G WG++C+  + I  AHV+C++L    A S    + +GK
Sbjct: 57   QLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGK 116

Query: 641  GNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGP 700
            G G IW    HCTG E  +  C     G + C   +   V+CS  +       NS     
Sbjct: 117  GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSL---- 172

Query: 701  TRPTIPEESAVACIESGQLRLVNGGGR-----CAGRVEIYHEGSWGTICDDSWDLSDAHV 755
                   E+    +E  ++R +    R       G VE+    +W  ICD  W   ++ V
Sbjct: 173  ---INQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRV 229

Query: 756  VCRQLGC-GEAINATG--SAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQ------ 806
            VC   G  GE    T              W   M C G E+ I  C     G Q      
Sbjct: 230  VCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKL---GPQVSLDPM 286

Query: 807  ---NCRHKEDAGVIC-----------SEFMS--------LRLTSEASREACAGRLEVFYN 844
                C +   A V C           S F          +RL   A      GR+EV  N
Sbjct: 287  KNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAY--IGEGRVEVLKN 344

Query: 845  GAWGTVGKSSMSETTVGVVCRQLGCAD-KGKINPASLDKAMSIPMWVDNVQCPKGPDTLW 903
            G WGTV        +  VVCR+LG    K  +  + L + +  P+ ++ +QC     ++ 
Sbjct: 345  GEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIG-PIHLNEIQCTGNEKSII 403

Query: 904  QCPSSPWEKRLASPSEETWITCDN-------KIRLQEGPTSCSGRVEIW--HGGS--WGT 952
             C  +  E +  +  E+  + C+        K+RL  G     GRVE+     GS  WG 
Sbjct: 404  DCKFNA-ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGM 462

Query: 953  VCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQG---TGPIWLNEVKCKGNESSLWDC 1008
            VC  +W + +A VVC+QLG G A  AF+E  +  G   +  + ++ VKC G E SL  C
Sbjct: 463  VCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHC 521



 Score =  149 bits (377), Expect = 1e-35
 Identities = 108/352 (30%), Positives = 153/352 (43%), Gaps = 56/352 (15%)

Query: 62  GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCP---TAIKAPGWANSSAGSGRIWMDHV 118
           G VEVK  + W  +C+  W+ +   V+C   G P   T         +S    R W   +
Sbjct: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263

Query: 119 SCRGNESALWDCKHDGWG-----KHSNCTHQQDAGVTCSDGSNLE--------------- 158
            C G E+ +  CK          K+  C +   A V+C  G                   
Sbjct: 264 DCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQ 323

Query: 159 --MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGE 216
             +RL  G  +  GR+E+   G WGTVCDD +++  ASV+CR+L  GSA      S  G+
Sbjct: 324 PLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQ 383

Query: 217 GSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVIC---SKGADLSLRLVDGVT 273
           G GPI  +++ C GNE ++ +CK        C+H EDAGV C   + G    LRL  G  
Sbjct: 384 GIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRN 442

Query: 274 ECSGRLEVRFQGE----WGTICDDGWDSYDAAVACKQLGCPTAVTAI-------GRVNAS 322
              GR+EV  +      WG +C   W   +A V C+QLG   A  A        G VN++
Sbjct: 443 PYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSN 502

Query: 323 KGFGHIWLDSVSCQGHEPAVWQCKHH-------EWGKHYCNHNEDAGVTCSD 367
           K    + +  V C G E ++  C+H        + G  Y      AGV CS+
Sbjct: 503 K----VVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQY-----GAGVACSE 545



 Score =  123 bits (309), Expect = 9e-28
 Identities = 70/202 (34%), Positives = 106/202 (52%), Gaps = 12/202 (5%)

Query: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
           +RL  G     GRVEV    EWGTVC++ W + + SV+C +LG  +A +A   +    G 
Sbjct: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385

Query: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSD---GSNLEMRLTRGGNM 167
           G I ++ + C GNE ++ DCK +   +   C H++DAGV C+    G   ++RL  G N 
Sbjct: 386 GPIHLNEIQCTGNEKSIIDCKFN--AESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNP 443

Query: 168 CSGRIEIKFQGR----WGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEG---SGP 220
             GR+E+  +      WG VC  N+ I  A V+CRQL  G A +    + +  G   S  
Sbjct: 444 YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503

Query: 221 IWFDDLICNGNESALWNCKHQG 242
           +    + C+G E +L +C+H G
Sbjct: 504 VVMSGVKCSGTELSLAHCRHDG 525



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 41/91 (45%), Positives = 59/91 (64%)

Query: 940  GRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCK 999
            GRVE+++ G WGTVCDD + +  A VVC++LG   A      + +G+G GPIWL+ + C 
Sbjct: 70   GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129

Query: 1000 GNESSLWDCPARRWGHSECGHKEDAAVNCTD 1030
            GNE++L  C +  WG ++C H ED  V C+D
Sbjct: 130  GNEATLAACTSNGWGVTDCKHTEDVGVVCSD 160



 Score = 70.9 bits (172), Expect = 7e-12
 Identities = 76/282 (26%), Positives = 110/282 (39%), Gaps = 37/282 (13%)

Query: 46  GTDKELRLVDGENKCSGRVEVKVQEE----WGTVCNNGWSMEAVSVICNQLG---CPTAI 98
           G  K+LRL  G N   GRVEV V+      WG VC   W +    V+C QLG      A 
Sbjct: 430 GLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAF 489

Query: 99  KAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH---QQDAGVTCSDGS 155
           +   + +    S ++ M  V C G E +L  C+HD  G+   C     Q  AGV CS+ +
Sbjct: 490 QETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHD--GEDVACPQGGVQYGAGVACSETA 547

Query: 156 N---LEMRLTRGGNMCSGRIEIKFQGRWGTVC--DDNFNIDHASVICRQLECGSAVSFSG 210
               L   + +       R     Q      C        D  +   R L   S +  +G
Sbjct: 548 PDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTGYRRLLRFSSQIHNNG 607

Query: 211 SSNFGEGSGP---IWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLR 267
            S+F   +G    IW D   C+ +  ++    H        D     G   ++G   S  
Sbjct: 608 QSDFRPKNGRHAWIWHD---CHRHYHSMEVFTHY-------DLLNLNGTKVAEGHKASFC 657

Query: 268 LVDGVTECSGRLEVRFQ----GEWGTICDDGWDSYDAAVACK 305
           L D  TEC G ++  ++    G+ G I    WD Y   + C+
Sbjct: 658 LED--TECEGDIQKNYECANFGDQG-ITMGCWDMYRHDIDCQ 696


>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
          Length = 756

 Score =  213 bits (542), Expect = 8e-55
 Identities = 147/466 (31%), Positives = 200/466 (42%), Gaps = 80/466 (17%)

Query: 170 GRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICN 229
           GR+E+  QG+WGTVCDDNF I  A+V CRQL   +A++++ S+ +G+G GPIW D++ C 
Sbjct: 44  GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103

Query: 230 GNESALWNCKHQGWGKHNCDHAEDAGVICS----------------------------KG 261
           G ES+L  C   GWG  +C H+ED GVIC                             K 
Sbjct: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKP 163

Query: 262 ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG---- 317
              S +    VTE  G +EV+++G W  +CD GW   ++ V C  LG P+ V        
Sbjct: 164 ILASAKQHSPVTE--GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYR 221

Query: 318 ------------RVNASKGFGHIWLDSVSCQGHEPAVWQCKHH---EWGK--HYCNHNED 360
                       R+ +       W+  V+C G EP +  C+       GK    C     
Sbjct: 222 KVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMH 281

Query: 361 AGVTCSDG-----------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWG 403
           A V+C  G                  +  +RLR G     G VEV + R  G VCD  W 
Sbjct: 282 AVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWN 341

Query: 404 LKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCD 463
           L  A VVCRQLG GSA +  +            L    C G E +L DC   +     C 
Sbjct: 342 LISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQ 401

Query: 464 HYEEAKITCSA-----HREPRLVGGDIPCSG----RVEVKHGDTWGSICDSDFSLEAASV 514
           H  +A + C+        + RL GG IP  G    +VEV     WGS+C  ++ L  A V
Sbjct: 402 HENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMV 461

Query: 515 LCRELQCGTVVSILGGAHFGEGN---GQIWAEEFQCEGHESHLSLC 557
            CR+L  G  +       F  G     ++     +C G E  L  C
Sbjct: 462 ACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQC 507



 Score =  207 bits (527), Expect = 4e-53
 Identities = 130/392 (33%), Positives = 177/392 (45%), Gaps = 69/392 (17%)

Query: 706  PEESAVACIESGQLRLVNGGGRCA-GRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGE 764
            P  S    + + +LRLV    +   GR+E+ H+G WGT+CDD++ + +A V CRQLG   
Sbjct: 19   PPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEA 78

Query: 765  AINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVIC------ 818
            A+    SA +G+G GPIWLD ++C G ES + QC S+GWG  +C H ED GVIC      
Sbjct: 79   ALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHR 138

Query: 819  ---SEFMSLRLTSEASR-----------------EACAGRLEVFYNGAWGTVGKSSMSET 858
               SE +S  L  +  R                     G +EV Y G W  V     +  
Sbjct: 139  GYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMN 198

Query: 859  TVGVVCRQLGCADKGKINPASLDKAMSIPM----------------WVDNV--------- 893
               VVC  LG   +  ++     K   + M                W+  V         
Sbjct: 199  NSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHM 258

Query: 894  ----------------QCPKGPDTLWQCPSSP-WEKRLASPSEETWITCDNKIRLQEGPT 936
                             CP G   +  C + P +      P  +     + ++RL+ G  
Sbjct: 259  ANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQ 318

Query: 937  SCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEV 996
               GRVE+     WGTVCD  W+L  A VVC+QLG G A +A   A  GQG GPI L+EV
Sbjct: 319  VGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEV 378

Query: 997  KCKGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
            +C+G E +L DCPA     + C H+ DAAV C
Sbjct: 379  RCRGYERTLSDCPALEGSQNGCQHENDAAVRC 410



 Score =  205 bits (521), Expect = 2e-52
 Identities = 152/497 (30%), Positives = 221/497 (44%), Gaps = 80/497 (16%)

Query: 43  SLGGTDKELRLVDGENKCS-GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAP 101
           SLG T  +LRLV  E+K   GR+EV  Q +WGTVC++ ++++  +V C QLG   A+   
Sbjct: 26  SLGTT--KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWA 83

Query: 102 GWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTC---------- 151
             A    G G IW+D+V C G ES+L  C  +GWG  S+C+H +D GV C          
Sbjct: 84  HSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGV-SDCSHSEDVGVICHPRRHRGYLS 142

Query: 152 --------SDGSNL-EMRL-------TRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASV 195
                     G  L E+RL        +   +  G +E+K++G W  VCD  + ++++ V
Sbjct: 143 ETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRV 202

Query: 196 ICRQLECGSAVSFSG--------------SSNFGE--GSGPIWFDDLICNGNESALWNCK 239
           +C  L   S V                   S           W   + C G E  + NC+
Sbjct: 203 VCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQ 262

Query: 240 HQ-----GWGKHNCDHAEDAGVICSKG-----------------ADLSLRLVDGVTECSG 277
            Q     G  +  C     A V C  G                  +  +RL  G     G
Sbjct: 263 VQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEG 322

Query: 278 RLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQG 337
           R+EV    +WGT+CD  W+   A+V C+QLG  +A  A+      +G G I L  V C+G
Sbjct: 323 RVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRG 382

Query: 338 HEPAVWQCKHHEWGKHYCNHNEDAGVTC---SDGSDLELRLRGGGSRCAGTVEVEIQ--- 391
           +E  +  C   E  ++ C H  DA V C   + G   ++RL GG     G +EV+++   
Sbjct: 383 YERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNG 442

Query: 392 -RLLGKVCDRGWGLKEADVVCRQLGCGSAL---KTSYQVYSKIQATNTWLFLSSCNGNET 447
               G VC   WGL EA V CRQLG G A+   K ++      +A    +    C+G E 
Sbjct: 443 VPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTEL 502

Query: 448 SLWDCKNWQWGGLTCDH 464
           +L  C+  + G + C H
Sbjct: 503 ALQQCQ--RHGPVHCSH 517



 Score =  202 bits (513), Expect = 2e-51
 Identities = 139/444 (31%), Positives = 195/444 (43%), Gaps = 63/444 (14%)

Query: 479 RLVGGDI-PCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGN 537
           RLVG +  P  GR+EV H   WG++CD +F+++ A+V CR+L     ++    A +G+G 
Sbjct: 33  RLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGE 92

Query: 538 GQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS------------------- 578
           G IW +  +C G ES L  C         CSHS DVGV+C                    
Sbjct: 93  GPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQ 152

Query: 579 --RYTEIRL------VNGKTPC-EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVA 629
             R  E+RL          +P  EG VE+K  G W  +C+  W + ++ V+C  L  G  
Sbjct: 153 GRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGML--GFP 210

Query: 630 LSTPGGARFGK------------------GNGQIWRHMFHCTGTEQHMGDCPVTALGASL 671
              P  + + +                       W H   C GTE HM +C V      +
Sbjct: 211 SEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQV-----QV 265

Query: 672 CPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGR 731
            P+       C G     +S        P + T P+    +  E  ++RL +G     GR
Sbjct: 266 APARGKLRPACPGGMHAVVSCVAGPHFRPPK-TKPQRKG-SWAEEPRVRLRSGAQVGEGR 323

Query: 732 VEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGK 791
           VE+     WGT+CD  W+L  A VVCRQLG G A  A   A  G+G GPI L E++C G 
Sbjct: 324 VEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGY 383

Query: 792 ESRIWQCHSHGWGQQNCRHKEDAGVICS----EFMS-LRLTSEASREACAGRLEVFYNGA 846
           E  +  C +    Q  C+H+ DA V C+     F + +RL      E     ++V  NG 
Sbjct: 384 ERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGV 443

Query: 847 --WGTVGKSSMSETTVGVVCRQLG 868
             WG+V   +   T   V CRQLG
Sbjct: 444 PRWGSVCSENWGLTEAMVACRQLG 467



 Score =  179 bits (455), Expect = 1e-44
 Identities = 143/512 (27%), Positives = 223/512 (43%), Gaps = 73/512 (14%)

Query: 581  TEIRLVNGKT-PCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
            T++RLV  ++ P EGR+E+   G WG++C+ ++ I++A V C+QL    AL+    A++G
Sbjct: 30   TKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYG 89

Query: 640  KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT-LSSCNSSSL 698
            +G G IW     C GTE  +  C     G S C   +   VIC   + +  LS   S++L
Sbjct: 90   QGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNAL 149

Query: 699  GPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR 758
            GP    + E      + S +           G VE+ +EG W  +CD  W ++++ VVC 
Sbjct: 150  GPQGRRLEEVRLKPILASAKQH----SPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCG 205

Query: 759  QLGCGEAINATGSAHFGE------------------GTGPIWLDEMKCNGKESRIWQCH- 799
             LG    +     +H+                         W+ ++ C G E  +  C  
Sbjct: 206  MLGFPSEVPV--DSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQV 263

Query: 800  ----SHGWGQQNCRHKEDAGVIC-------------------SEFMSLRLTSEASREACA 836
                + G  +  C     A V C                   +E   +RL S A  +   
Sbjct: 264  QVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGA--QVGE 321

Query: 837  GRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCAD-KGKINPASLDKAMSIPMWVDNVQC 895
            GR+EV  N  WGTV     +  +  VVCRQLG    +  +  A L + +  P+ +  V+C
Sbjct: 322  GRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLG-PIHLSEVRC 380

Query: 896  PKGPDTLWQCPSSPWEKRLASPSEETWITCD-------NKIRLQEGPTSCSG----RVEI 944
                 TL  CP+    +       +  + C+       N++RL  G     G    +VE+
Sbjct: 381  RGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEV 440

Query: 945  WHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGT---GPIWLNEVKCKGN 1001
                 WG+VC ++W L +A V C+QLG G A+ A+KE  F  GT     + ++ V+C G 
Sbjct: 441  NGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGT 500

Query: 1002 ESSLWDCPARRWGHSECGH---KEDAAVNCTD 1030
            E +L  C  +R G   C H   +  A V+C D
Sbjct: 501  ELALQQC--QRHGPVHCSHGGGRFLAGVSCMD 530



 Score =  164 bits (415), Expect = 4e-40
 Identities = 141/526 (26%), Positives = 206/526 (39%), Gaps = 103/526 (19%)

Query: 372 ELRLRGGGSRCA-GTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKI 430
           +LRL G  S+   G +EV  Q   G VCD  + ++EA V CRQLG  +AL  ++      
Sbjct: 31  KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQ 90

Query: 431 QATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRLVGGDIP---- 486
                WL    C G E+SL  C +  WG   C H E+  + C   R    +   +     
Sbjct: 91  GEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALG 150

Query: 487 ------------------------CSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCG 522
                                     G VEVK+   W  +CD  +++  + V+C  L   
Sbjct: 151 PQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFP 210

Query: 523 TVVSILGGAHFGE------------------GNGQIWAEEFQCEGHESHLSLCPVAPRP- 563
           + V +   +H+                         W  +  C G E H++ C V   P 
Sbjct: 211 SEVPV--DSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPA 268

Query: 564 ----EGTCSHSRDVGVVC-------------------SRYTEIRLVNGKTPCEGRVELKT 600
                  C       V C                   +    +RL +G    EGRVE+  
Sbjct: 269 RGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLM 328

Query: 601 LGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMG 660
              WG++C+  W++  A V+C+QL  G A     GAR G+G G I      C G E+ + 
Sbjct: 329 NRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLS 388

Query: 661 DCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLR 720
           DCP      + C  E  A+V C+      +   N   L   R  IPEE            
Sbjct: 389 DCPALEGSQNGCQHENDAAVRCN---VPNMGFQNQVRLAGGR--IPEE------------ 431

Query: 721 LVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGT-- 778
                G    +VE+     WG++C ++W L++A V CRQLG G AI+A     F  GT  
Sbjct: 432 -----GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPR 486

Query: 779 -GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRH---KEDAGVICSE 820
              + +  ++C+G E  + QC  H  G  +C H   +  AGV C +
Sbjct: 487 AQEVVMSGVRCSGTELALQQCQRH--GPVHCSHGGGRFLAGVSCMD 530



 Score =  157 bits (397), Expect = 5e-38
 Identities = 107/358 (29%), Positives = 155/358 (43%), Gaps = 52/358 (14%)

Query: 62  GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPG------W----------AN 105
           G VEVK +  W  VC+ GW+M    V+C  LG P+ +          W            
Sbjct: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236

Query: 106 SSAGSGRIWMDHVSCRGNESALWDCKHD---GWGK-HSNCTHQQDAGVTCSDGSNLE--- 158
           S       W+  V+C G E  + +C+       GK    C     A V+C  G +     
Sbjct: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK 296

Query: 159 --------------MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGS 204
                         +RL  G  +  GR+E+    +WGTVCD  +N+  ASV+CRQL  GS
Sbjct: 297 TKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGS 356

Query: 205 AVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVIC---SKG 261
           A      +  G+G GPI   ++ C G E  L +C      ++ C H  DA V C   + G
Sbjct: 357 AREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMG 416

Query: 262 ADLSLRLVDGVTECSGRLEVRFQ----GEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG 317
               +RL  G     G LEV+ +      WG++C + W   +A VAC+QLG   A+ A  
Sbjct: 417 FQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYK 476

Query: 318 RV---NASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNED---AGVTCSDGS 369
                + +     + +  V C G E A+ QC+ H  G  +C+H      AGV+C D +
Sbjct: 477 ETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRH--GPVHCSHGGGRFLAGVSCMDSA 532



 Score =  116 bits (291), Expect = 1e-25
 Identities = 78/228 (34%), Positives = 111/228 (48%), Gaps = 16/228 (7%)

Query: 48  DKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSS 107
           +  +RL  G     GRVEV +  +WGTVC++ W++ + SV+C QLG  +A +A   A   
Sbjct: 308 EPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLG 367

Query: 108 AGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTC---SDGSNLEMRLTRG 164
            G G I +  V CRG E  L DC     G  + C H+ DA V C   + G   ++RL  G
Sbjct: 368 QGLGPIHLSEVRCRGYERTLSDCPALE-GSQNGCQHENDAAVRCNVPNMGFQNQVRLAGG 426

Query: 165 GNMCSGRIEIKFQ----GRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEG--- 217
                G +E++ +     RWG+VC +N+ +  A V CRQL  G A+     + F  G   
Sbjct: 427 RIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPR 486

Query: 218 SGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAED---AGVICSKGA 262
           +  +    + C+G E AL  C  Q  G  +C H      AGV C   A
Sbjct: 487 AQEVVMSGVRCSGTELALQQC--QRHGPVHCSHGGGRFLAGVSCMDSA 532


>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
          Length = 753

 Score =  212 bits (539), Expect = 2e-54
 Identities = 151/504 (29%), Positives = 230/504 (45%), Gaps = 87/504 (17%)

Query: 25  SPFTITVVLLLSACFVTSS--------LGGTDKELRLVDGENK-CSGRVEVKVQEEWGTV 75
           SP+ + + LL S+C  + S         G      RL     K   GRVE++   EWGT+
Sbjct: 10  SPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTI 69

Query: 76  CNNGWSMEAVSVICNQLGCPTAIKAPGWANSSA---GSGRIWMDHVSCRGNESALWDCKH 132
           C++ ++++A  ++C +LG     +A GW +S+    G+GRIW+D++SC G E ++ +C  
Sbjct: 70  CDDDFTLQAAHILCRELGFT---EATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECAS 126

Query: 133 DGWGKHSNCTHQQDAGVTCSD-------GSNL----------EMRL-------TRGGNMC 168
            GWG +S+CTH +DAGV C D        SN+          E+R+        R   + 
Sbjct: 127 RGWG-NSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVT 185

Query: 169 SGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGS----------SNFGEGS 218
            G +E++    W  VCD  ++  ++ V+C  L   S    + +           +FG   
Sbjct: 186 EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFG--- 242

Query: 219 GPIWFDDLICNGNESALWNCKHQGWGKHN---CDHAEDAGVICSKG-------------- 261
                  + C G E+ L  C  + +  ++   C     A V C  G              
Sbjct: 243 ----LHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQ 298

Query: 262 ----ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG 317
                +  +RL  G     GR+EV     WGT+CD  WD + A+V C++LG  +A  A+ 
Sbjct: 299 SKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALS 358

Query: 318 RVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS---DGSDLELR 374
                +G G I L  V C G E ++W+C H       C+H++DAGV C+    G++  +R
Sbjct: 359 GARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIR 418

Query: 375 LRGGGSRCAGTVEVEI----QRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKI 430
           L GG S+  G VEV+I        G +C   WG  EA V CRQLG G A     + +   
Sbjct: 419 LSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWD 478

Query: 431 QATNTWLFLSS--CNGNETSLWDC 452
               T + +S   C G E SL  C
Sbjct: 479 SGNITEVVMSGVRCTGTELSLDQC 502



 Score =  206 bits (523), Expect = 1e-52
 Identities = 136/416 (32%), Positives = 188/416 (45%), Gaps = 68/416 (16%)

Query: 693  CNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGR-CAGRVEIYHEGSWGTICDDSWDLS 751
            C+S    P+  T PE+ A +  +  + RL     +   GRVEI   G WGTICDD + L 
Sbjct: 20   CSSCLGSPSPSTGPEKKAGS--QGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQ 77

Query: 752  DAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHK 811
             AH++CR+LG  EA   T SA +G GTG IWLD + C+G E  + +C S GWG  +C H 
Sbjct: 78   AAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHD 137

Query: 812  EDAGVICSEFM--------------SLRLTSEASREACA----------GRLEVFYNGAW 847
            EDAGVIC +                 L++     R A            G +EV     W
Sbjct: 138  EDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGW 197

Query: 848  GTVGKSSMSETTVGVVCRQLGCADKGKINPA---------------------SLDKAMSI 886
              V     S     VVC  LG   + ++N A                       +  +S+
Sbjct: 198  SQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSL 257

Query: 887  PMWV-----DNVQCPKG--------PDTLWQCPSSPWEKRLASPSEETWITCDNKIRLQE 933
                     D  +CP G        P  ++   S   +++ + P  E       ++RL+ 
Sbjct: 258  CSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEA------RVRLKG 311

Query: 934  GPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWL 993
            G     GRVE+    +WGTVCD  WDL  A VVC++LG G A +A   A  GQG G I L
Sbjct: 312  GAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHL 371

Query: 994  NEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCT-DISVQKTPQKATTGRSSRQ 1048
            +EV+C G E SLW CP +     +C H +DA V C    +  +T  + + GRS  +
Sbjct: 372  SEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHE 427



 Score =  203 bits (516), Expect = 8e-52
 Identities = 140/463 (30%), Positives = 197/463 (42%), Gaps = 56/463 (12%)

Query: 486 PCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEF 545
           P  GRVE++    WG+ICD DF+L+AA +LCREL           A +G G G+IW +  
Sbjct: 53  PYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNL 112

Query: 546 QCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS-------------------RYTEIRLV 586
            C G E  ++ C         C+H  D GV+C                    +  E+R+ 
Sbjct: 113 SCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIR 172

Query: 587 N----GKTPC---EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
                G+ P    EG VE++    W  +C+  W   ++HV+C  L  G        A F 
Sbjct: 173 PAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFY 230

Query: 640 KGNGQIWRHMFH-----CTGTEQHMGDCPVT---ALGASLCPSEQVASVICSGNQSQTLS 691
           +   Q  +H F      C GTE H+  C +    A   + CP    A V C        S
Sbjct: 231 RLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAAS 290

Query: 692 SCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLS 751
           S         + + P+  A       ++RL  G     GRVE+    +WGT+CD  WDL 
Sbjct: 291 SGQKKQ----QQSKPQGEA-------RVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLH 339

Query: 752 DAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHK 811
            A VVCR+LG G A  A   A  G+G G I L E++C+G+E  +W+C       ++C H 
Sbjct: 340 AASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHS 399

Query: 812 EDAGVICS---EFMSLRLTSEASREACAGRLEVFYNG----AWGTVGKSSMSETTVGVVC 864
           +DAGV C+        R+     R    GR+EV   G     WG +           V C
Sbjct: 400 QDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVAC 459

Query: 865 RQLGC--ADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQC 905
           RQLG   A+ G       D      + +  V+C     +L QC
Sbjct: 460 RQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQC 502



 Score =  198 bits (503), Expect = 3e-50
 Identities = 147/473 (31%), Positives = 205/473 (43%), Gaps = 67/473 (14%)

Query: 170 GRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICN 229
           GR+EI+  G WGT+CDD+F +  A ++CR+L    A  ++ S+ +G G+G IW D+L C+
Sbjct: 56  GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115

Query: 230 GNESALWNCKHQGWGKHNCDHAEDAGVICS-------------------KGADLSLRLVD 270
           G E ++  C  +GWG  +C H EDAGVIC                    +  ++ +R   
Sbjct: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175

Query: 271 G-------VTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPT---AVTAIGRVN 320
           G       VTE  G +EVR    W  +CD GW ++++ V C  LG P+      A  R+ 
Sbjct: 176 GWGRRPLPVTE--GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLL 233

Query: 321 ASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKH---YCNHNEDAGVTCSDG--------- 368
           A +      L  V+C G E  +  C    +  +    C     A V+C  G         
Sbjct: 234 AQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQ 293

Query: 369 ---------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSA 419
                     +  +RL+GG     G VEV      G VCDR W L  A VVCR+LG GSA
Sbjct: 294 KKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSA 353

Query: 420 LKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS-----A 474
            +               L    C+G E SLW C +       C H ++A + C+     A
Sbjct: 354 REALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGA 413

Query: 475 HREPRLVGGDIPCSGRVEVKHGD----TWGSICDSDFSLEAASVLCRELQCGTVVSILGG 530
               RL GG     GRVEV+ G      WG IC  D+    A V CR+L  G     L  
Sbjct: 414 ETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQE 473

Query: 531 A-HFGEGN-GQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSR---DVGVVCS 578
             ++  GN  ++     +C G E  L  C        TC  +      GV+CS
Sbjct: 474 TWYWDSGNITEVVMSGVRCTGTELSLDQC-AHHGTHITCKRTGTRFTAGVICS 525



 Score =  166 bits (421), Expect = 9e-41
 Identities = 134/488 (27%), Positives = 204/488 (41%), Gaps = 58/488 (11%)

Query: 589  KTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRH 648
            + P EGRVE++  G WG++C+  + ++ AH+LC++L    A      A++G G G+IW  
Sbjct: 51   RKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLD 110

Query: 649  MFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEE 708
               C+GTEQ + +C     G S C  ++ A VIC   +    S  N          + E 
Sbjct: 111  NLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSN----------VIEV 160

Query: 709  SAVACIESGQLRLVNGGGR-----CAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLG-- 761
                 +E  ++R   G GR       G VE+     W  +CD  W   ++HVVC  LG  
Sbjct: 161  EHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFP 220

Query: 762  CGEAINATGSAHFGE-GTGPIWLDEMKCNGKESRIWQCHSHGWGQQN---CRHKEDAGVI 817
              + +NA       +       L  + C G E+ +  C    +   +   C     A V 
Sbjct: 221  SEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVS 280

Query: 818  C--------SEFMSLRLTSEASREACA----------GRLEVFYNGAWGTVGKSSMSETT 859
            C        S     +  S+   EA            GR+EV     WGTV         
Sbjct: 281  CVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHA 340

Query: 860  VGVVCRQLGCAD-KGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPS 918
              VVCR+LG    +  ++ A + + M   + +  V+C     +LW+CP         S S
Sbjct: 341  ASVVCRELGFGSAREALSGARMGQGMG-AIHLSEVRCSGQELSLWKCPHKNITAEDCSHS 399

Query: 919  EETWITC-------DNKIRLQEGPTSCSGRVEIWHGG----SWGTVCDDSWDLDDAQVVC 967
            ++  + C       + +IRL  G +   GRVE+  GG     WG +C D W   +A V C
Sbjct: 400  QDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVAC 459

Query: 968  QQLGCGPALKAFKEAEFGQGTG--PIWLNEVKCKGNESSLWDCPARRWGHSEC---GHKE 1022
            +QLG G A    +E  +        + ++ V+C G E SL  C A    H  C   G + 
Sbjct: 460  RQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQC-AHHGTHITCKRTGTRF 518

Query: 1023 DAAVNCTD 1030
             A V C++
Sbjct: 519  TAGVICSE 526



 Score =  164 bits (415), Expect = 4e-40
 Identities = 136/503 (27%), Positives = 193/503 (38%), Gaps = 92/503 (18%)

Query: 384 GTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCN 443
           G VE++     G +CD  + L+ A ++CR+LG   A   ++           WL   SC+
Sbjct: 56  GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115

Query: 444 GNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRLVGGDI------------------ 485
           G E S+ +C +  WG   C H E+A + C   R P     ++                  
Sbjct: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175

Query: 486 --------PCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGN 537
                      G VEV+  D W  +CD  +S   + V+C  L   +   +   A F    
Sbjct: 176 GWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRV--NAAFYRLL 233

Query: 538 GQIWAEEF-----QCEGHESHLSLCPVA---PRPEGTCSHSRDVGVVC------------ 577
            Q     F      C G E+HLSLC +          C       V C            
Sbjct: 234 AQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQ 293

Query: 578 --------SRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVA 629
                        +RL  G  P EGRVE+     WG++C+  WD+  A V+C++L  G A
Sbjct: 294 KKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSA 353

Query: 630 LSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
                GAR G+G G I      C+G E  +  CP   + A  C   Q A V C+      
Sbjct: 354 REALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN------ 407

Query: 690 LSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGS----WGTICD 745
                          +P   A       ++RL  G  +  GRVE+   G     WG IC 
Sbjct: 408 ---------------LPYTGAET-----RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICG 447

Query: 746 DSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTG--PIWLDEMKCNGKESRIWQCHSHGW 803
           D W   +A V CRQLG G A +      + +      + +  ++C G E  + QC  HG 
Sbjct: 448 DDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG- 506

Query: 804 GQQNCRH---KEDAGVICSEFMS 823
               C+    +  AGVICSE  S
Sbjct: 507 THITCKRTGTRFTAGVICSETAS 529



 Score =  160 bits (406), Expect = 5e-39
 Identities = 112/349 (32%), Positives = 164/349 (46%), Gaps = 39/349 (11%)

Query: 62  GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTA--IKAPGWANSSAGSGRIWMDH-V 118
           G VEV++ + W  VC+ GWS     V+C  LG P+   + A  +   +      +  H V
Sbjct: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246

Query: 119 SCRGNESALWDCKHDGWGKH--SNCTHQQDAGVTCSDG------------------SNLE 158
           +C G E+ L  C  + +  +  + C     A V+C  G                      
Sbjct: 247 ACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEAR 306

Query: 159 MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGS 218
           +RL  G +   GR+E+     WGTVCD  +++  ASV+CR+L  GSA      +  G+G 
Sbjct: 307 VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGM 366

Query: 219 GPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS---KGADLSLRLVDGVTEC 275
           G I   ++ C+G E +LW C H+     +C H++DAGV C+    GA+  +RL  G ++ 
Sbjct: 367 GAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQH 426

Query: 276 SGRLEVRFQG----EWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRV--NASKGFGHIW 329
            GR+EV+  G     WG IC D W + +A VAC+QLG   A   +       S     + 
Sbjct: 427 EGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVV 486

Query: 330 LDSVSCQGHEPAVWQCKHHEWGKHY-CNHNE---DAGVTCSD-GSDLEL 373
           +  V C G E ++ QC HH  G H  C        AGV CS+  SDL L
Sbjct: 487 MSGVRCTGTELSLDQCAHH--GTHITCKRTGTRFTAGVICSETASDLLL 533



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 60/254 (23%), Positives = 100/254 (39%), Gaps = 40/254 (15%)

Query: 832  REACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVD 891
            R+   GR+E+   G WGT+     +     ++CR+LG  +      ++     +  +W+D
Sbjct: 51   RKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLD 110

Query: 892  NVQCPKGPDTLWQCPSSPW----------------EKRLASPSEETWITCDNKIRLQE-- 933
            N+ C     ++ +C S  W                ++RL   S+   I  ++ ++++E  
Sbjct: 111  NLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVR 170

Query: 934  -GPTSCSGR---------VEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALK----AF 979
              P    GR         VE+     W  VCD  W   ++ VVC  LG  P+ K    AF
Sbjct: 171  IRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGF-PSEKRVNAAF 229

Query: 980  KEAEFGQGTGPIWLNEVKCKGNESSLWDCPA---RRWGHSECGHKEDAAVNCTDISVQKT 1036
                  +      L+ V C G E+ L  C     R    + C     A V+C    V   
Sbjct: 230  YRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC----VPGP 285

Query: 1037 PQKATTGRSSRQSS 1050
               A++G+  +Q S
Sbjct: 286  VYAASSGQKKQQQS 299


>gi|194018748 CD6 molecule [Homo sapiens]
          Length = 668

 Score =  201 bits (512), Expect = 2e-51
 Identities = 122/358 (34%), Positives = 174/358 (48%), Gaps = 24/358 (6%)

Query: 368 GSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSY--- 424
           G  L +RL  G S C+GTVEV ++      C   W  + A+ VCR LGCG A   S    
Sbjct: 40  GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99

Query: 425 ---QVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEA--------KITCS 473
              ++     A NT +  ++      +L  C   +W    C+  E A        ++TC+
Sbjct: 100 PTPELPPPPAAGNTSVAANATLAGAPALL-CSGAEWR--LCEVVEHACRSDGRRARVTCA 156

Query: 474 AHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHF 533
            +R  RLV G   C+GRVE+     WGS+CD  + LE A V+CR+L CG  V  L G HF
Sbjct: 157 ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF 216

Query: 534 GEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCE 593
             G G I  ++  C G E++L  CP  P  +  C H  D G VCS +   RL  G   CE
Sbjct: 217 TPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGADRCE 275

Query: 594 GRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCT 653
           G+VE+   G W ++C+S W   +A VLCQ L CG A+  P G           R  + C 
Sbjct: 276 GQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSG----RMYYSCN 331

Query: 654 GTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAV 711
           G E  + +C      ++LC     A V+CS   S++L + ++  +  +  T+  ES+V
Sbjct: 332 GEELTLSNCSWRFNNSNLCSQSLAARVLCSA--SRSLHNLSTPEVPASVQTVTIESSV 387



 Score =  200 bits (509), Expect = 5e-51
 Identities = 114/308 (37%), Positives = 157/308 (50%), Gaps = 32/308 (10%)

Query: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642
           +RL NG + C G VE++   +W   C + WD   A  +C+ L CG A      ++     
Sbjct: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGA---EAASQLAPPT 101

Query: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVA---SVICSGNQSQTLSSCNSSSLG 699
            ++                 P  A   S+  +  +A   +++CSG + +       +   
Sbjct: 102 PEL---------------PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRS 146

Query: 700 PTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQ 759
             R      + V C E+  LRLV+GGG CAGRVE+   G WG++CDD+WDL DAHVVCRQ
Sbjct: 147 DGR-----RARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQ 201

Query: 760 LGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
           LGCG A+ A    HF  G GPI  D++ C+G E+ +W C     GQ  C HKEDAG +CS
Sbjct: 202 LGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS 260

Query: 820 EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGC---ADKGKIN 876
           E  S RLT  A R  C G++EV + G W TV  S    +   V+C+ LGC    ++ K  
Sbjct: 261 EHQSWRLTGGADR--CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGL 318

Query: 877 PASLDKAM 884
           P SL   M
Sbjct: 319 PHSLSGRM 326



 Score =  198 bits (503), Expect = 3e-50
 Identities = 119/340 (35%), Positives = 170/340 (50%), Gaps = 32/340 (9%)

Query: 154 GSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFS---- 209
           G  L +RLT G + CSG +E++ +  W   C   ++   A  +CR L CG A + S    
Sbjct: 40  GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99

Query: 210 -----------GSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNC-DHAEDAGVI 257
                      G+++    +       L+C+G E  L         +H C      A V 
Sbjct: 100 PTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVV-----EHACRSDGRRARVT 154

Query: 258 CSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG 317
           C++    +LRLVDG   C+GR+E+   GEWG++CDD WD  DA V C+QLGC  AV A+ 
Sbjct: 155 CAENR--ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212

Query: 318 RVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLELRLRG 377
            ++ + G G I  D V+C G E  +W C     G+HYC H EDAG  CS+      RL G
Sbjct: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQ--SWRLTG 269

Query: 378 GGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWL 437
           G  RC G VEV  + +   VCD  W   EA V+C+ LGCG+A++    +   +     + 
Sbjct: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY- 328

Query: 438 FLSSCNGNETSLWDCKNWQWGGLT-CDHYEEAKITCSAHR 476
              SCNG E +L +C +W++     C     A++ CSA R
Sbjct: 329 ---SCNGEELTLSNC-SWRFNNSNLCSQSLAARVLCSASR 364



 Score =  194 bits (493), Expect = 4e-49
 Identities = 119/343 (34%), Positives = 163/343 (47%), Gaps = 43/343 (12%)

Query: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGC-------------PTA 97
           +RL +G + CSG VEV+++  W   C   W   A   +C  LGC             P  
Sbjct: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104

Query: 98  IKAPGWANSS--AGSGRIWMDHVSCRGNESALWD-----CKHDGWGKHSNCTHQQDAGVT 150
              P   N+S  A +       + C G E  L +     C+ DG          + A VT
Sbjct: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDG----------RRARVT 154

Query: 151 CSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSG 210
           C++  N  +RL  GG  C+GR+E+   G WG+VCDD ++++ A V+CRQL CG AV    
Sbjct: 155 CAE--NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212

Query: 211 SSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVD 270
             +F  G GPI  D + C+G E+ LW+C     G+H C H EDAG +CS+    S RL  
Sbjct: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSE--HQSWRLTG 269

Query: 271 GVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWL 330
           G   C G++EV F+G W T+CD  W   +A V C+ LGC TA      V   KG  H   
Sbjct: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTA------VERPKGLPHSLS 323

Query: 331 DSV--SCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDL 371
             +  SC G E  +  C       + C+ +  A V CS    L
Sbjct: 324 GRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366



 Score =  171 bits (432), Expect = 5e-42
 Identities = 116/363 (31%), Positives = 151/363 (41%), Gaps = 59/363 (16%)

Query: 479 RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSI----------- 527
           RL  G   CSG VEV+   +W   C + +   AA  +CR L CG   +            
Sbjct: 46  RLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELP 105

Query: 528 ----LGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTC-SHSRDVGVVCSRYTE 582
                G            A    C G E  L  C V    E  C S  R   V C+    
Sbjct: 106 PPPAAGNTSVAANATLAGAPALLCSGAEWRL--CEVV---EHACRSDGRRARVTCAENRA 160

Query: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642
           +RLV+G   C GRVE+   G WGS+C+  WD+EDAHV+C+QL CG A+    G  F  G 
Sbjct: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220

Query: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR 702
           G I R   +C+G E ++ DCP    G   C  ++ A  +CS +QS               
Sbjct: 221 GPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQS--------------- 264

Query: 703 PTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGC 762
                            RL  G  RC G+VE++  G W T+CD  W  S+A V+C+ LGC
Sbjct: 265 ----------------WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC 308

Query: 763 GEAI-NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEF 821
           G A+    G  H   G          CNG+E  +  C         C     A V+CS  
Sbjct: 309 GTAVERPKGLPHSLSGR-----MYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSAS 363

Query: 822 MSL 824
            SL
Sbjct: 364 RSL 366



 Score =  154 bits (390), Expect = 3e-37
 Identities = 83/217 (38%), Positives = 118/217 (54%), Gaps = 8/217 (3%)

Query: 48  DKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSS 107
           ++ LRLVDG   C+GRVE+    EWG+VC++ W +E   V+C QLGC  A++A    + +
Sbjct: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217

Query: 108 AGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNM 167
            G G I  D V+C G E+ LWDC   G      C H++DAG  CS+  +   RLT G + 
Sbjct: 218 PGRGPIHRDQVNCSGAEAYLWDC--PGLPGQHYCGHKEDAGAVCSE--HQSWRLTGGADR 273

Query: 168 CSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLI 227
           C G++E+ F+G W TVCD  +    A V+C+ L CG+AV           SG +++    
Sbjct: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS--- 329

Query: 228 CNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADL 264
           CNG E  L NC  +    + C  +  A V+CS    L
Sbjct: 330 CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366



 Score =  150 bits (380), Expect = 5e-36
 Identities = 118/408 (28%), Positives = 169/408 (41%), Gaps = 47/408 (11%)

Query: 719  LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCG--EAIN--------- 767
            +RL NG   C+G VE+  E SW   C   WD   A  VCR LGCG  EA +         
Sbjct: 45   VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104

Query: 768  ----ATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS 823
                A G+              + C+G E R+ +   H       R    A V C+E  +
Sbjct: 105  PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR----ARVTCAENRA 160

Query: 824  LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKA 883
            LRL       ACAGR+E+  +G WG+V   +       VVCRQLGC    +  P      
Sbjct: 161  LRLVDGGG--ACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218

Query: 884  MSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCD--NKIRLQEGPTSCSGR 941
               P+  D V C      LW CP  P +       E+    C      RL  G   C G+
Sbjct: 219  GRGPIHRDQVNCSGAEAYLWDCPGLPGQ-HYCGHKEDAGAVCSEHQSWRLTGGADRCEGQ 277

Query: 942  VEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGN 1001
            VE+   G W TVCD  W   +A+V+CQ LGCG A++  K       +G ++ +   C G 
Sbjct: 278  VEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGE 333

Query: 1002 ESSLWDCPARRWGHSECGHKEDAAVNCT------DISVQKTPQKATT------------G 1043
            E +L +C  R    + C     A V C+      ++S  + P    T             
Sbjct: 334  ELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSVTVKIEN 393

Query: 1044 RSSRQSSFIAVGI-LGVVLLAIFVALFFLTKKRRQRQRLAVSSRGENL 1090
            + SR+   +   I LG++LL   + + F+  + + +  L V    ++L
Sbjct: 394  KESRELMLLIPSIVLGILLLGSLIFIAFILLRIKGKYALPVMVNHQHL 441



 Score =  135 bits (339), Expect = 3e-31
 Identities = 99/313 (31%), Positives = 146/313 (46%), Gaps = 30/313 (9%)

Query: 820  EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADK---GKIN 876
            E + +RLT+ +S  +C+G +EV    +W     +         VCR LGC       ++ 
Sbjct: 41   ERLPVRLTNGSS--SCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLA 98

Query: 877  PASLD----KAMSIPMWVDNVQCPKGPDTLWQCPSSPW------EKRLASPSEETWITC- 925
            P + +     A        N      P  L  C  + W      E    S      +TC 
Sbjct: 99   PPTPELPPPPAAGNTSVAANATLAGAPALL--CSGAEWRLCEVVEHACRSDGRRARVTCA 156

Query: 926  -DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEF 984
             +  +RL +G  +C+GRVE+   G WG+VCDD+WDL+DA VVC+QLGCG A++A     F
Sbjct: 157  ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF 216

Query: 985  GQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATTGR 1044
              G GPI  ++V C G E+ LWDCP    G   CGHKEDA   C++    +      TG 
Sbjct: 217  TPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWR-----LTGG 270

Query: 1045 SSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQRLAVSS---RGENLVHQIQYREMNS 1101
            + R    + V   G V   +  + ++ ++ +   Q L   +   R + L H +  R   S
Sbjct: 271  ADRCEGQVEVHFRG-VWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYS 329

Query: 1102 CLNADDLDLMNSS 1114
            C N ++L L N S
Sbjct: 330  C-NGEELTLSNCS 341


>gi|5031863 galectin 3 binding protein [Homo sapiens]
          Length = 585

 Score =  135 bits (339), Expect = 3e-31
 Identities = 61/129 (47%), Positives = 82/129 (63%)

Query: 714 IESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAH 773
           +  G +RL +GG    GRVEI++ G WGT+CD+ WDL+DA VVCR LG   A  A G A 
Sbjct: 19  VNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAA 78

Query: 774 FGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASRE 833
           FG+G+GPI LDE++C G E+ +  C S GW + NCRH+ DAGV+C+       T + SRE
Sbjct: 79  FGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRE 138

Query: 834 ACAGRLEVF 842
                 ++F
Sbjct: 139 LSEALGQIF 147



 Score =  117 bits (292), Expect = 8e-26
 Identities = 55/105 (52%), Positives = 70/105 (66%)

Query: 926  DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFG 985
            D  +RL +G  +  GRVEI++ G WGTVCD+ WDL DA VVC+ LG   A +A   A FG
Sbjct: 21   DGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFG 80

Query: 986  QGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTD 1030
            QG+GPI L+EV+C G E+SL DC +  W  S C H+ DA V CT+
Sbjct: 81   QGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTN 125



 Score =  112 bits (279), Expect = 3e-24
 Identities = 58/142 (40%), Positives = 82/142 (57%), Gaps = 13/142 (9%)

Query: 158 EMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEG 217
           +MRL  GG    GR+EI ++G+WGTVCD+ +++  ASV+CR L   +A    G + FG+G
Sbjct: 23  DMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQG 82

Query: 218 SGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGA------DLSLRLVDG 271
           SGPI  D++ C G E++L +CK  GW K NC H  DAGV+C+         DLS  L + 
Sbjct: 83  SGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELSEA 142

Query: 272 VTE-------CSGRLEVRFQGE 286
           + +       C   + V  QGE
Sbjct: 143 LGQIFDSQRGCDLSISVNVQGE 164



 Score =  104 bits (260), Expect = 4e-22
 Identities = 52/114 (45%), Positives = 69/114 (60%), Gaps = 1/114 (0%)

Query: 40  VTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIK 99
           V  + G  D ++RL DG     GRVE+  + +WGTVC+N W +   SV+C  LG   A +
Sbjct: 13  VAGTQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQ 72

Query: 100 APGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSD 153
           A G A    GSG I +D V C G E++L DCK  GW K SNC H++DAGV C++
Sbjct: 73  ALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLK-SNCRHERDAGVVCTN 125



 Score =  101 bits (251), Expect = 5e-21
 Identities = 46/105 (43%), Positives = 62/105 (59%)

Query: 263 DLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNAS 322
           D  +RL DG     GR+E+ ++G+WGT+CD+ WD  DA+V C+ LG   A  A+GR    
Sbjct: 21  DGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFG 80

Query: 323 KGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSD 367
           +G G I LD V C G E ++  CK   W K  C H  DAGV C++
Sbjct: 81  QGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTN 125



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 42/103 (40%), Positives = 56/103 (54%)

Query: 479 RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNG 538
           RL  G     GRVE+ +   WG++CD+ + L  ASV+CR L        LG A FG+G+G
Sbjct: 25  RLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSG 84

Query: 539 QIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYT 581
            I  +E QC G E+ L+ C      +  C H RD GVVC+  T
Sbjct: 85  PIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNET 127



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 40/108 (37%), Positives = 58/108 (53%)

Query: 582 EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKG 641
           ++RL +G    +GRVE+   G WG++C++ WD+ DA V+C+ L    A    G A FG+G
Sbjct: 23  DMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQG 82

Query: 642 NGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
           +G I      CTGTE  + DC       S C  E+ A V+C+     T
Sbjct: 83  SGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRST 130



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 36/105 (34%), Positives = 51/105 (48%)

Query: 369 SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYS 428
           +D ++RL  GG+   G VE+  +   G VCD  W L +A VVCR LG  +A +   +   
Sbjct: 20  NDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAF 79

Query: 429 KIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS 473
              +    L    C G E SL DCK+  W    C H  +A + C+
Sbjct: 80  GQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 31/94 (32%), Positives = 43/94 (45%)

Query: 837 GRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCP 896
           GR+E+FY G WGTV  +    T   VVCR LG  +  +    +     S P+ +D VQC 
Sbjct: 35  GRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCT 94

Query: 897 KGPDTLWQCPSSPWEKRLASPSEETWITCDNKIR 930
               +L  C S  W K       +  + C N+ R
Sbjct: 95  GTEASLADCKSLGWLKSNCRHERDAGVVCTNETR 128


>gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo
            sapiens]
          Length = 451

 Score =  123 bits (308), Expect = 1e-27
 Identities = 57/107 (53%), Positives = 66/107 (61%)

Query: 923  ITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEA 982
            +T   K+RL  G     GRVEI H G WGT+CDD W++   QVVC+ LG        K A
Sbjct: 344  LTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAA 403

Query: 983  EFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029
             FGQGTGPIWLNEV C G ESS+ +C  R+WG   C H EDA V CT
Sbjct: 404  HFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  119 bits (299), Expect = 1e-26
 Identities = 54/102 (52%), Positives = 66/102 (64%)

Query: 718 QLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEG 777
           ++RLV G G   GRVEI H G WGTICDD W++    VVCR LG         +AHFG+G
Sbjct: 349 KVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQG 408

Query: 778 TGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
           TGPIWL+E+ C G+ES I +C    WG + C H EDAGV C+
Sbjct: 409 TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  100 bits (249), Expect = 8e-21
 Identities = 41/102 (40%), Positives = 63/102 (61%)

Query: 158 EMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEG 217
           ++RL  G     GR+EI   G+WGT+CDD + +    V+CR L      +   +++FG+G
Sbjct: 349 KVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQG 408

Query: 218 SGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS 259
           +GPIW +++ C G ES++  CK + WG   C H+EDAGV C+
Sbjct: 409 TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 97.4 bits (241), Expect = 7e-20
 Identities = 43/101 (42%), Positives = 59/101 (58%)

Query: 266 LRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGF 325
           +RLV G     GR+E+   G+WGTICDD W+     V C+ LG P         +  +G 
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 326 GHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS 366
           G IWL+ V C G E ++ +CK  +WG   C+H+EDAGVTC+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 44/108 (40%), Positives = 57/108 (52%)

Query: 471 TCSAHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGG 530
           T +   + RLVGG  P  GRVE+ H   WG+ICD  + +    V+CR L    V ++   
Sbjct: 343 TLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKA 402

Query: 531 AHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS 578
           AHFG+G G IW  E  C G ES +  C +       CSHS D GV C+
Sbjct: 403 AHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 40/103 (38%), Positives = 60/103 (58%), Gaps = 1/103 (0%)

Query: 50  ELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAG 109
           ++RLV G     GRVE+    +WGT+C++ W +    V+C  LG P        A+   G
Sbjct: 349 KVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQG 408

Query: 110 SGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152
           +G IW++ V C G ES++ +CK   WG  + C+H +DAGVTC+
Sbjct: 409 TGPIWLNEVFCFGRESSIEECKIRQWGTRA-CSHSEDAGVTCT 450



 Score = 80.5 bits (197), Expect = 8e-15
 Identities = 36/110 (32%), Positives = 56/110 (50%)

Query: 574 GVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTP 633
           G   + +T++RLV G  P EGRVE+   G WG++C+  W++    V+C+ L      +  
Sbjct: 341 GNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVH 400

Query: 634 GGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICS 683
             A FG+G G IW +   C G E  + +C +   G   C   + A V C+
Sbjct: 401 KAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 34/102 (33%), Positives = 47/102 (46%)

Query: 372 ELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQ 431
           ++RL GG     G VE+      G +CD  W ++   VVCR LG           +    
Sbjct: 349 KVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQG 408

Query: 432 ATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS 473
               WL    C G E+S+ +CK  QWG   C H E+A +TC+
Sbjct: 409 TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 2/122 (1%)

Query: 804 GQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVV 863
           G +  + ++ +G   + F  +RL   +      GR+E+ ++G WGT+           VV
Sbjct: 330 GPKGQKGEKGSGNTLTPFTKVRLVGGSGPHE--GRVEILHSGQWGTICDDRWEVRVGQVV 387

Query: 864 CRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWI 923
           CR LG      ++ A+     + P+W++ V C     ++ +C    W  R  S SE+  +
Sbjct: 388 CRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGV 447

Query: 924 TC 925
           TC
Sbjct: 448 TC 449


>gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]
          Length = 495

 Score =  119 bits (297), Expect = 2e-26
 Identities = 51/101 (50%), Positives = 63/101 (62%)

Query: 719 LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGT 778
           +RLVNG G   GRVE+YH+  WGT+CDD WD  D  VVCR LG         +A FG+GT
Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452

Query: 779 GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
           G IW+D++ C G E  I++C    WG  NC H EDA V C+
Sbjct: 453 GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  115 bits (289), Expect = 2e-25
 Identities = 49/100 (49%), Positives = 64/100 (64%)

Query: 929  IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGT 988
            IRL  G     GRVE++H   WGTVCDD WD  D  VVC+ LG     + ++ A FGQGT
Sbjct: 393  IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452

Query: 989  GPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
            G IW+++V CKG E +++ C   +WG + CGH EDA+V C
Sbjct: 453  GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTC 492



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 47/118 (39%), Positives = 63/118 (53%), Gaps = 3/118 (2%)

Query: 249 DHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLG 308
           D A DA  +    A + +RLV+G     GR+EV     WGT+CDDGWD  D  V C+ LG
Sbjct: 379 DRAGDASGV---EAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLG 435

Query: 309 CPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS 366
                         +G G IW+D V+C+G E  +++C   +WG   C H EDA VTC+
Sbjct: 436 FRGVEEVYRTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 45/119 (37%), Positives = 62/119 (52%), Gaps = 4/119 (3%)

Query: 146 DAGVTCSDGSNLE----MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLE 201
           + G    D S +E    +RL  G     GR+E+    RWGTVCDD ++     V+CR L 
Sbjct: 376 EKGDRAGDASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLG 435

Query: 202 CGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSK 260
                    ++ FG+G+G IW DD+ C G E  ++ C    WG  NC HAEDA V C++
Sbjct: 436 FRGVEEVYRTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCNR 494



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 43/102 (42%), Positives = 58/102 (56%), Gaps = 1/102 (0%)

Query: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110
           +RLV+G     GRVEV     WGTVC++GW  +   V+C  LG     +    A    G+
Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452

Query: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152
           GRIWMD V+C+G E  ++ C    WG  +NC H +DA VTC+
Sbjct: 453 GRIWMDDVACKGTEETIFRCSFSKWGV-TNCGHAEDASVTCN 493



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 37/102 (36%), Positives = 53/102 (51%)

Query: 479 RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNG 538
           RLV G  P  GRVEV H   WG++CD  +  +   V+CR L    V  +   A FG+G G
Sbjct: 394 RLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGTG 453

Query: 539 QIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRY 580
           +IW ++  C+G E  +  C  +      C H+ D  V C+R+
Sbjct: 454 RIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCNRH 495



 Score = 77.4 bits (189), Expect = 7e-14
 Identities = 40/101 (39%), Positives = 55/101 (54%)

Query: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642
           IRLVNG  P EGRVE+     WG++C+  WD +D  V+C+ L           ARFG+G 
Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452

Query: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICS 683
           G+IW     C GTE+ +  C  +  G + C   + ASV C+
Sbjct: 453 GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 43/121 (35%), Positives = 59/121 (48%), Gaps = 6/121 (4%)

Query: 360 DAGVTCSDGSDLE----LRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLG 415
           + G    D S +E    +RL  G     G VEV   R  G VCD GW  K+ DVVCR LG
Sbjct: 376 EKGDRAGDASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLG 435

Query: 416 CGSALKTSYQVYSKIQAT-NTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSA 474
               ++  Y+     Q T   W+   +C G E +++ C   +WG   C H E+A +TC+ 
Sbjct: 436 F-RGVEEVYRTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCNR 494

Query: 475 H 475
           H
Sbjct: 495 H 495



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 25/90 (27%), Positives = 45/90 (50%)

Query: 837 GRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCP 896
           GR+EV+++  WGTV      +    VVCR LG     ++   +     +  +W+D+V C 
Sbjct: 404 GRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGTGRIWMDDVACK 463

Query: 897 KGPDTLWQCPSSPWEKRLASPSEETWITCD 926
              +T+++C  S W       +E+  +TC+
Sbjct: 464 GTEETIFRCSFSKWGVTNCGHAEDASVTCN 493


>gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]
          Length = 782

 Score =  113 bits (282), Expect = 1e-24
 Identities = 55/114 (48%), Positives = 72/114 (63%), Gaps = 3/114 (2%)

Query: 709 SAVACIESGQLRLVNGGGRCAG--RVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAI 766
           SA      G++RLV   G  +G  RVE++  G WGT+CDDSW++S A VVCRQLG   A+
Sbjct: 663 SASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAV 722

Query: 767 NATGSAHFGEGTG-PIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
            A   A FG+G   PI LD+++C G E  + +C  +G G  NC H EDAGV+CS
Sbjct: 723 RAVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  105 bits (262), Expect = 2e-22
 Identities = 54/105 (51%), Positives = 68/105 (64%), Gaps = 3/105 (2%)

Query: 158 EMRLTRGGNMCSG--RIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFG 215
           E+RL R   + SG  R+E+   GRWGTVCDD++NI  A+V+CRQL    AV     + FG
Sbjct: 672 EVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFG 731

Query: 216 E-GSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS 259
           + GS PI  DD+ C G E  L  C+H G G HNC+H EDAGV+CS
Sbjct: 732 QGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  103 bits (258), Expect = 7e-22
 Identities = 54/107 (50%), Positives = 70/107 (65%), Gaps = 3/107 (2%)

Query: 926  DNKIRLQE--GPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAE 983
            D ++RL    G +S SGRVE++ GG WGTVCDDSW++  A VVC+QLG   A++A K AE
Sbjct: 670  DGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAE 729

Query: 984  FGQGTG-PIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029
            FGQG   PI L++V+C G E +L +C     G   C H EDA V C+
Sbjct: 730  FGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 94.0 bits (232), Expect = 7e-19
 Identities = 50/107 (46%), Positives = 64/107 (59%), Gaps = 3/107 (2%)

Query: 263 DLSLRLVD--GVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVN 320
           D  +RLV   G++  SGR+EV   G WGT+CDD W+   AAV C+QLG   AV A+ R  
Sbjct: 670 DGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAE 729

Query: 321 ASKGFG-HIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS 366
             +G    I LD V C G E  + +C+H+  G H C H+EDAGV CS
Sbjct: 730 FGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 50/108 (46%), Positives = 65/108 (60%), Gaps = 4/108 (3%)

Query: 48  DKELRLVD--GENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWAN 105
           D E+RLV   G +  SGRVEV V   WGTVC++ W++   +V+C QLG   A++A   A 
Sbjct: 670 DGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAE 729

Query: 106 -SSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152
               GS  I +D V C G E  L +C+H+G G H NC H +DAGV CS
Sbjct: 730 FGQGGSLPILLDDVRCAGWERNLLECQHNGVGTH-NCEHDEDAGVVCS 776



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 1/92 (1%)

Query: 488 SGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNG-QIWAEEFQ 546
           SGRVEV  G  WG++CD  +++  A+V+CR+L     V  +  A FG+G    I  ++ +
Sbjct: 685 SGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVR 744

Query: 547 CEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS 578
           C G E +L  C         C H  D GVVCS
Sbjct: 745 CAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 36/105 (34%), Positives = 55/105 (52%), Gaps = 3/105 (2%)

Query: 582 EIRLVN--GKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
           E+RLV   G +   GRVE+   G WG++C+  W+I  A V+C+QL    A+     A FG
Sbjct: 672 EVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFG 731

Query: 640 KGNG-QIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICS 683
           +G    I      C G E+++ +C    +G   C  ++ A V+CS
Sbjct: 732 QGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 4/114 (3%)

Query: 370 DLELRL--RGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQV- 426
           D E+RL    G S  +G VEV +    G VCD  W +  A VVCRQLG   A++   +  
Sbjct: 670 DGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAE 729

Query: 427 YSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRL 480
           + +  +    L    C G E +L +C++   G   C+H E+A + CS H+ P L
Sbjct: 730 FGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS-HQNPDL 782



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 1/106 (0%)

Query: 824 LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGK-INPASLDK 882
           +RL   A   + +GR+EVF  G WGTV   S + +   VVCRQLG A   + +  A   +
Sbjct: 673 VRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQ 732

Query: 883 AMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDNK 928
             S+P+ +D+V+C      L +C  +          E+  + C ++
Sbjct: 733 GGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCSHQ 778


>gi|5803080 macrophage receptor with collagenous structure [Homo
           sapiens]
          Length = 520

 Score =  110 bits (274), Expect = 1e-23
 Identities = 52/106 (49%), Positives = 65/106 (61%), Gaps = 9/106 (8%)

Query: 716 SGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGC--GEAINATGSAH 773
           S  +R+V    R  GR E+Y+ G+WGTICDD W  SDA V CR LG   G A+   G+  
Sbjct: 421 SVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGA-- 476

Query: 774 FGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
              GTG IWLD ++C G ES +W C  + WG  +C H+EDAGV CS
Sbjct: 477 ---GTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  109 bits (272), Expect = 2e-23
 Identities = 45/104 (43%), Positives = 64/104 (61%), Gaps = 3/104 (2%)

Query: 926  DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFG 985
            +N + ++   +S  GR E+++ G+WGT+CDD W   DA V C+ LG       +K    G
Sbjct: 419  ENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYK---VG 475

Query: 986  QGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029
             GTG IWL+ V+C+G ES+LW C    WGH +C H+EDA V C+
Sbjct: 476  AGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  100 bits (250), Expect = 6e-21
 Identities = 49/103 (47%), Positives = 62/103 (60%), Gaps = 5/103 (4%)

Query: 264 LSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASK 323
           +S+R+V       GR EV + G WGTICDD W + DA V C+ LG      A+ +V A  
Sbjct: 422 VSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKG-RALYKVGA-- 476

Query: 324 GFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS 366
           G G IWLD+V C+G E  +W C  + WG H C+H EDAGV CS
Sbjct: 477 GTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 41/95 (43%), Positives = 52/95 (54%), Gaps = 3/95 (3%)

Query: 165 GNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFD 224
           G+   GR E+ + G WGT+CDD +    A V CR L      +       G G+G IW D
Sbjct: 428 GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALY---KVGAGTGQIWLD 484

Query: 225 DLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS 259
           ++ C G ES LW+C    WG H+C H EDAGV CS
Sbjct: 485 NVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 44/108 (40%), Positives = 59/108 (54%), Gaps = 6/108 (5%)

Query: 45  GGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWA 104
           G     +R+V   N+  GR EV     WGT+C++ W      V C  LG     K     
Sbjct: 418 GENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYS---KGRALY 472

Query: 105 NSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152
              AG+G+IW+D+V CRG ES LW C  + WG H +C+H++DAGV CS
Sbjct: 473 KVGAGTGQIWLDNVQCRGTESTLWSCTKNSWG-HHDCSHEEDAGVECS 519



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 36/90 (40%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 489 GRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCE 548
           GR EV +  TWG+ICD ++    A V CR L      ++      G G GQIW +  QC 
Sbjct: 433 GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALY---KVGAGTGQIWLDNVQCR 489

Query: 549 GHESHLSLCPVAPRPEGTCSHSRDVGVVCS 578
           G ES L  C         CSH  D GV CS
Sbjct: 490 GTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 36/106 (33%), Positives = 54/106 (50%), Gaps = 11/106 (10%)

Query: 822 MSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLD 881
           +S+R+   ++R    GR EV+Y+G WGT+       +   V CR LG + KG+    +L 
Sbjct: 422 VSVRIVGSSNR----GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYS-KGR----ALY 472

Query: 882 K--AMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC 925
           K  A +  +W+DNVQC     TLW C  + W     S  E+  + C
Sbjct: 473 KVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVEC 518



 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 36/103 (34%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQL--KCGVALSTPGGARFGK 640
           +R+V       GR E+   G WG++C+  W   DA V C+ L    G AL      + G 
Sbjct: 424 VRIVGSSN--RGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALY-----KVGA 476

Query: 641 GNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICS 683
           G GQIW     C GTE  +  C   + G   C  E+ A V CS
Sbjct: 477 GTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 34/105 (32%), Positives = 48/105 (45%), Gaps = 5/105 (4%)

Query: 369 SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYS 428
           + + +R+ G  +R  G  EV      G +CD  W   +A V CR LG     +  Y+V +
Sbjct: 420 NSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKG-RALYKVGA 476

Query: 429 KIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS 473
                  WL    C G E++LW C    WG   C H E+A + CS
Sbjct: 477 G--TGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519


>gi|166197668 CD5 molecule [Homo sapiens]
          Length = 495

 Score = 70.9 bits (172), Expect = 7e-12
 Identities = 80/321 (24%), Positives = 118/321 (36%), Gaps = 83/321 (25%)

Query: 263 DLSLRLVDGVTECSGRLEVRFQGEWGTICDDGW--------DSYDAAVACKQLGCPTAVT 314
           D   RL    ++C G+LEV  +  W  +C   W        D   A+  C++L C   ++
Sbjct: 32  DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91

Query: 315 AIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSD---- 370
            +G    +    +    S+ C G   +   C H       C+     G+TC +       
Sbjct: 92  -LGPFLVT----YTPQSSIICYGQLGSFSNCSHSR--NDMCH---SLGLTCLEPQKTTPP 141

Query: 371 -----------------LELRLRGGGSRCAGTVEVEIQRLLGKVC----DRGWGLKEADV 409
                            L+L  + GG  CAG VE     L G +     D+   L+  + 
Sbjct: 142 TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLE--NF 199

Query: 410 VCRQLGCGSALK-------------------TSYQVYSKIQATNTWLFLSSCNGNETSLW 450
           +C  L CGS LK                       +  KIQ        SSC   E    
Sbjct: 200 LCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQN-------SSCTSLEHCFR 252

Query: 451 DCKNWQWGGLTCDHYEEAKITCSAHR---EPRLVGGDIPCSGRVEVKHGDTWGSICDSDF 507
             K  + G +         + CS  +   + RLVGG   C G VEV+ G  W ++CDS  
Sbjct: 253 KIKPQKSGRVLA-------LLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSS 305

Query: 508 SLEAA--SVLCRELQCGTVVS 526
           +  +     +CRE QCG+V S
Sbjct: 306 ARSSLRWEEVCREQQCGSVNS 326



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 78/306 (25%), Positives = 120/306 (39%), Gaps = 63/306 (20%)

Query: 370 DLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLK--------EADVVCRQLGCGSALK 421
           D + RL    S+C G +EV ++     VC + WG          +A  VC++L CG  L 
Sbjct: 32  DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91

Query: 422 -----TSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHR 476
                 +Y   S I         S+C+ +   +  C +    GLTC   E  K T    R
Sbjct: 92  LGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDM--CHSL---GLTC--LEPQKTTPPTTR 144

Query: 477 EP-------------RLVG--GDIPCSGRVEVKHGDTWGSIC--DSDFSLEAASVLCREL 519
            P             +LV   G   C+G VE   G   G+I     D + +  + LC  L
Sbjct: 145 PPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNL 204

Query: 520 QCGTVVSILGGAHFGEGNGQIWAEEFQC--------EGHESHLSLCPVAPRPEGTCSHSR 571
           QCG+ +  L     G         E Q             + L  C    +P+ +    R
Sbjct: 205 QCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKS---GR 261

Query: 572 DVGVVCSRY---TEIRLVNGKTPCEGRVELKTLGAWGSLCNS-------HWDIEDAHVLC 621
            + ++CS +    + RLV G + CEG VE++    W +LC+S        W+      +C
Sbjct: 262 VLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWE-----EVC 316

Query: 622 QQLKCG 627
           ++ +CG
Sbjct: 317 REQQCG 322



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 66/305 (21%), Positives = 109/305 (35%), Gaps = 64/305 (20%)

Query: 33  LLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEA-------- 84
           +L+++C    S    D + RL    +KC G++EV +++ W  VC+  W   +        
Sbjct: 17  MLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQ 76

Query: 85  VSVICNQLGCPTAIK-APGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143
            S +C +L C   +   P     +  S       + C G   +  +C H    ++  C  
Sbjct: 77  ASKVCQRLNCGVPLSLGPFLVTYTPQSS------IICYGQLGSFSNCSH---SRNDMC-- 125

Query: 144 QQDAGVTCSDGSNLEMRLTR---------------------GGNMCSGRIEIKFQGRWGT 182
               G+TC +        TR                     GG  C+G +E       GT
Sbjct: 126 -HSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGT 184

Query: 183 VCDD--NFNIDHASVICRQLECGSAVSFSGSSNFGEGSGP-----------IW-FDDLIC 228
           +  +  +   D  + +C  L+CGS +     +  G    P            W   +  C
Sbjct: 185 ISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSC 244

Query: 229 NGNESALWNCKHQGWGKHNCDHAEDAGVICSK-GADLSLRLVDGVTECSGRLEVRFQGEW 287
              E      K Q  G+          ++CS     +  RLV G + C G +EVR   +W
Sbjct: 245 TSLEHCFRKIKPQKSGR-------VLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQW 297

Query: 288 GTICD 292
             +CD
Sbjct: 298 AALCD 302



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 92/430 (21%), Positives = 155/430 (36%), Gaps = 97/430 (22%)

Query: 718  QLRLVNGGGRCAGRVEIYHEGSWGTICDDSW--------DLSDAHVVCRQLGCGEAINAT 769
            Q RL     +C G++E+Y +  W  +C  SW        D S A  VC++L CG  ++  
Sbjct: 34   QARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL- 92

Query: 770  GSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKED-----AGVICSEFMS- 823
                     GP  +        +S I  C+       NC H  +      G+ C E    
Sbjct: 93   ---------GPFLVTYTP----QSSII-CYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKT 138

Query: 824  --------------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETT--VG 861
                                L+L +++  + CAG +E +     GT+   +  +T     
Sbjct: 139  TPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLEN 198

Query: 862  VVCRQLGCA---------DKGKI-NPASLDKAMSIPM-W-VDNVQCPKGPDTLWQCPSSP 909
             +C  L C          + G+  +P    +   +P+ W + N  C        +     
Sbjct: 199  FLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQK 258

Query: 910  WEKRLASPSEETWITCDN-----KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDA- 963
              + LA       + C       + RL  G + C G VE+  G  W  +CD S       
Sbjct: 259  SGRVLA-------LLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLR 311

Query: 964  -QVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKE 1022
             + VC++  CG ++ +++  + G  T              S    CP ++   S+C    
Sbjct: 312  WEEVCREQQCG-SVNSYRVLDAGDPT--------------SRGLFCPHQKL--SQCHELW 354

Query: 1023 DAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFF--LTKK-RRQRQ 1079
            +    C  + V           +   +S I   +L VVLL +   L +  L KK R+++Q
Sbjct: 355  ERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQ 414

Query: 1080 RLAVSSRGEN 1089
            R  +   G N
Sbjct: 415  RQWIGPTGMN 424



 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 108/465 (23%), Positives = 161/465 (34%), Gaps = 124/465 (26%)

Query: 582 EIRLVNGKTPCEGRVELKTLGAWGSLCNSHW--------DIEDAHVLCQQLKCGVALSTP 633
           + RL    + C+G++E+     W  +C+  W        D   A  +CQ+L CGV LS  
Sbjct: 34  QARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS-- 91

Query: 634 GGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSC 693
                                            LG  L      +S+IC G Q  + S+C
Sbjct: 92  ---------------------------------LGPFLVTYTPQSSIICYG-QLGSFSNC 117

Query: 694 NSS------SLG------------PTRP---TIPEESAVACIESGQLRLVNGGGRCAGRV 732
           + S      SLG             TRP   T PE +A   +   QL   +GG  CAG V
Sbjct: 118 SHSRNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRL---QLVAQSGGQHCAGVV 174

Query: 733 EIYHEGSWGTICDDSWDLSD--AHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790
           E Y     GTI  ++ D +    + +C  L CG  +        G    P          
Sbjct: 175 EFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---------- 224

Query: 791 KESRIWQCHSHGWGQQN--CRHKEDA-------------GVICSEF---MSLRLTSEASR 832
            E R  Q     W  QN  C   E                ++CS F   +  RL   +S 
Sbjct: 225 GEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSS- 283

Query: 833 EACAGRLEVFYNGAWGTVGKSSMSETTV--GVVCRQLGCADKGKINPASLDKAMSIPMWV 890
             C G +EV     W  +  SS + +++    VCR+  C               S  ++ 
Sbjct: 284 -ICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLF- 341

Query: 891 DNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSW 950
               CP     L QC    WE+   S  ++ ++TC +       P   +        G+ 
Sbjct: 342 ----CPH--QKLSQC-HELWERN--SYCKKVFVTCQD-----PNPAGLA-------AGTV 380

Query: 951 GTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNE 995
            ++      L    VVC  L     +K F++ +  Q  GP  +N+
Sbjct: 381 ASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGPTGMNQ 425



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 8/64 (12%)

Query: 921 TWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSW--------DLDDAQVVCQQLGC 972
           +W   D + RL    + C G++E++    W  VC  SW        D   A  VCQ+L C
Sbjct: 27  SWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNC 86

Query: 973 GPAL 976
           G  L
Sbjct: 87  GVPL 90



 Score = 37.7 bits (86), Expect = 0.062
 Identities = 15/54 (27%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 157 LEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHA--SVICRQLECGSAVSF 208
           ++ RL  G ++C G +E++   +W  +CD +          +CR+ +CGS  S+
Sbjct: 274 VQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSY 327



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 13/104 (12%)

Query: 52  RLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAV--SVICNQLGCPTAIKAPGWANSSAG 109
           RLV G + C G VEV+   +W  +C++  +  ++    +C +  C +             
Sbjct: 277 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPT 336

Query: 110 SGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSD 153
           S  ++  H         L  C H+ W ++S C   +   VTC D
Sbjct: 337 SRGLFCPH-------QKLSQC-HELWERNSYC---KKVFVTCQD 369


>gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo
            sapiens]
          Length = 388

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 29/54 (53%), Positives = 34/54 (62%), Gaps = 4/54 (7%)

Query: 980  KEAEFGQG----TGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029
            ++ E G G    TGPIWLNEV C G ESS+ +C  R+WG   C H EDA V CT
Sbjct: 334  QKGEKGSGNTLSTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 23/42 (54%), Positives = 29/42 (69%)

Query: 778 TGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819
           TGPIWL+E+ C G+ES I +C    WG + C H EDAGV C+
Sbjct: 346 TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 21/41 (51%), Positives = 29/41 (70%)

Query: 326 GHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS 366
           G IWL+ V C G E ++ +CK  +WG   C+H+EDAGVTC+
Sbjct: 347 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 20/42 (47%), Positives = 29/42 (69%)

Query: 218 SGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS 259
           +GPIW +++ C G ES++  CK + WG   C H+EDAGV C+
Sbjct: 346 TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 1/58 (1%)

Query: 95  PTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152
           P   K    + ++  +G IW++ V C G ES++ +CK   WG  + C+H +DAGVTC+
Sbjct: 331 PKGQKGEKGSGNTLSTGPIWLNEVFCFGRESSIEECKIRQWGTRA-CSHSEDAGVTCT 387



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 17/38 (44%), Positives = 23/38 (60%)

Query: 436 WLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS 473
           WL    C G E+S+ +CK  QWG   C H E+A +TC+
Sbjct: 350 WLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 20/49 (40%), Positives = 23/49 (46%), Gaps = 4/49 (8%)

Query: 534 GEGN----GQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS 578
           G GN    G IW  E  C G ES +  C +       CSHS D GV C+
Sbjct: 339 GSGNTLSTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 6/59 (10%)

Query: 631 STPGGARFGKGNGQ------IWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICS 683
           S P G +  KG+G       IW +   C G E  + +C +   G   C   + A V C+
Sbjct: 329 SGPKGQKGEKGSGNTLSTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 30.8 bits (68), Expect = 7.5
 Identities = 12/39 (30%), Positives = 20/39 (51%)

Query: 887 PMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC 925
           P+W++ V C     ++ +C    W  R  S SE+  +TC
Sbjct: 348 PIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 386


>gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]
          Length = 2699

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 59/240 (24%), Positives = 84/240 (35%), Gaps = 31/240 (12%)

Query: 75  VCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSC----RGNESALWDC 130
           +C +GW      V   Q   P             G G   M   +C    +G      DC
Sbjct: 565 LCFSGWKGTECDVPTTQCIDPQC----------GGRGICIMGSCACNSGYKGESCEEADC 614

Query: 131 KHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFN- 189
              G   H  C H +        GSN E+  T   + CSG      Q      CD N+  
Sbjct: 615 IDPGCSNHGVCIHGECHCSPGWGGSNCEILKTMCPDQCSGH-GTYLQESGSCTCDPNWTG 673

Query: 190 IDHASVICRQLECGS-AVSFSGSSNFGEG-SGPIWFDDLICNGNESALWNCKHQGWGKHN 247
            D ++ IC  ++CGS  V   G+    EG +GP   +   C+   +    CK    GK  
Sbjct: 674 PDCSNEIC-SVDCGSHGVCMGGTCRCEEGWTGPAC-NQRACHPRCAEHGTCKD---GKCE 728

Query: 248 CDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQL 307
           C    +       G   ++    G+   +GR  +   G W  +C  GW      VA + L
Sbjct: 729 CSQGWN-------GEHCTIEGCPGLCNSNGRCTLDQNG-WHCVCQPGWRGAGCDVAMETL 780


>gi|119392081 complement factor I preproprotein [Homo sapiens]
          Length = 583

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 364 TCSDGSDLELRLRGGGSRCAGTVEVEI--QRLLGKVCDRGWGLKEADVVCRQLGCGSALK 421
           TC+      + L+ G +   G VEV++  Q     +C   W ++EA+V C  LG      
Sbjct: 105 TCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGAD 164

Query: 422 TSYQV-YSKIQATNTWLFLSSCNGNETSLWDC 452
           T  +   S +   +T      C G ETSL +C
Sbjct: 165 TQRRFKLSDLSINSTECLHVHCRGLETSLAEC 196



 Score = 37.7 bits (86), Expect = 0.062
 Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 6/102 (5%)

Query: 53  LVDGENKCSGRVEVKVQEEWGT--VCNNGWSMEAVSVICNQLGCPT-AIKAPGWANSSAG 109
           L  G     G VEVK+ ++  T  +C + WSM   +V C  LG    A     +  S   
Sbjct: 116 LKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLS 175

Query: 110 SGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTC 151
                  HV CRG E++L +C    + K     +Q  A V C
Sbjct: 176 INSTECLHVHCRGLETSLAECT---FTKRRTMGYQDFADVVC 214



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 25/94 (26%), Positives = 38/94 (40%), Gaps = 6/94 (6%)

Query: 672 CPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQ--LRLVNGGGRCA 729
           CP    A  +C+ N+    + C   SL    P     +   C   G+  + L +G     
Sbjct: 67  CPKNGTA--VCATNRRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSE 124

Query: 730 GRVEI--YHEGSWGTICDDSWDLSDAHVVCRQLG 761
           G VE+    +     IC  SW + +A+V C  LG
Sbjct: 125 GIVEVKLVDQDKTMFICKSSWSMREANVACLDLG 158



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 9/89 (10%)

Query: 583 IRLVNGKTPCEGRVELKTLGAWGSL--CNSHWDIEDAHVLCQQLKCGVALSTPGGARFGK 640
           + L +G T  EG VE+K +    ++  C S W + +A+V C  L  G         RF  
Sbjct: 114 VSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVAC--LDLGFQQGADTQRRFKL 171

Query: 641 G----NGQIWRHMFHCTGTEQHMGDCPVT 665
                N     H+ HC G E  + +C  T
Sbjct: 172 SDLSINSTECLHV-HCRGLETSLAECTFT 199



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 3/91 (3%)

Query: 258 CSKGADLSLRLVDGVTECSGRLEVRFQGEWGT--ICDDGWDSYDAAVACKQLGCPTAVTA 315
           C+     S+ L  G T+  G +EV+   +  T  IC   W   +A VAC  LG       
Sbjct: 106 CTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADT 165

Query: 316 IGRVNASK-GFGHIWLDSVSCQGHEPAVWQC 345
             R   S           V C+G E ++ +C
Sbjct: 166 QRRFKLSDLSINSTECLHVHCRGLETSLAEC 196



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 9/105 (8%)

Query: 929  IRLQEGPTSCSGRVEIWHGGSWGT--VCDDSWDLDDAQVVCQQLGC---GPALKAFKEAE 983
            + L+ G T   G VE+       T  +C  SW + +A V C  LG        + FK ++
Sbjct: 114  VSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSD 173

Query: 984  FGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
                +       V C+G E+SL +C   +      G+++ A V C
Sbjct: 174  LSINSTECL--HVHCRGLETSLAECTFTK--RRTMGYQDFADVVC 214


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score = 37.7 bits (86), Expect = 0.062
 Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 1/47 (2%)

Query: 279 LEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG-RVNASKG 324
           L+V     W T+C D W  + A VAC QLG P+ V++   RV++ +G
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSSDNLRVSSLEG 163



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)

Query: 718 QLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLG 761
           + R V  GG+ A  ++++   SW T+C D W    A+V C QLG
Sbjct: 104 EYRCVRVGGQNAV-LQVFTAASWKTMCSDDWKGHYANVACAQLG 146



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 34  LLSACFVTSSLGGTDKELRLV--DGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQ 91
           L++ C   S     + E R V   G+N     ++V     W T+C++ W     +V C Q
Sbjct: 88  LIARCDGVSDCKDGEDEYRCVRVGGQNAV---LQVFTAASWKTMCSDDWKGHYANVACAQ 144

Query: 92  LGCPTAIKAPGWANSS 107
           LG P+ + +     SS
Sbjct: 145 LGFPSYVSSDNLRVSS 160



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 12/30 (40%), Positives = 17/30 (56%)

Query: 942 VEIWHGGSWGTVCDDSWDLDDAQVVCQQLG 971
           ++++   SW T+C D W    A V C QLG
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLG 146



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 2/57 (3%)

Query: 151 CSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVS 207
           C DG + E R  R G   +  +++     W T+C D++   +A+V C QL   S VS
Sbjct: 98  CKDGED-EYRCVRVGGQ-NAVLQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVS 152


>gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo
           sapiens]
          Length = 344

 Score = 37.7 bits (86), Expect = 0.062
 Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 1/47 (2%)

Query: 279 LEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG-RVNASKG 324
           L+V     W T+C D W  + A VAC QLG P+ V++   RV++ +G
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSSDNLRVSSLEG 163



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)

Query: 718 QLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLG 761
           + R V  GG+ A  ++++   SW T+C D W    A+V C QLG
Sbjct: 104 EYRCVRVGGQNAV-LQVFTAASWKTMCSDDWKGHYANVACAQLG 146



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 34  LLSACFVTSSLGGTDKELRLV--DGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQ 91
           L++ C   S     + E R V   G+N     ++V     W T+C++ W     +V C Q
Sbjct: 88  LIARCDGVSDCKDGEDEYRCVRVGGQNAV---LQVFTAASWKTMCSDDWKGHYANVACAQ 144

Query: 92  LGCPTAIKAPGWANSS 107
           LG P+ + +     SS
Sbjct: 145 LGFPSYVSSDNLRVSS 160



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 12/30 (40%), Positives = 17/30 (56%)

Query: 942 VEIWHGGSWGTVCDDSWDLDDAQVVCQQLG 971
           ++++   SW T+C D W    A V C QLG
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLG 146



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 2/57 (3%)

Query: 151 CSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVS 207
           C DG + E R  R G   +  +++     W T+C D++   +A+V C QL   S VS
Sbjct: 98  CKDGED-EYRCVRVGGQ-NAVLQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVS 152


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 48/185 (25%), Positives = 72/185 (38%), Gaps = 20/185 (10%)

Query: 360 DAGVTCSDGSDLE--LRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCG 417
           D  + C DGSD    +R   G +   G V   IQ +    C   W  + ++ VC+ LG G
Sbjct: 663 DGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLG 722

Query: 418 SALKTSYQVYSKIQATNTWLFLSSCNGNE-----TSLWDCKNWQWGGLTCDHYEEAKITC 472
           S   +S  ++S    T+   F+      +     T    C       L C+H    K   
Sbjct: 723 SG-NSSKPIFS----TDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLA 777

Query: 473 SAHREPRLVGGDIPCSGRVEVKHGDTWG-------SICDSDFSLEAA-SVLCRELQCGTV 524
           +    P++VGG     G      G  +G       S+  SD+ + AA  V  R L+    
Sbjct: 778 AQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKW 837

Query: 525 VSILG 529
            +ILG
Sbjct: 838 TAILG 842



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 26/119 (21%)

Query: 253 DAGVICSKGADLS--LRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCP 310
           D  + C  G+D +  +R  +G T  +G +  R Q  W T C + W +  +   C+ LG  
Sbjct: 663 DGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLG-- 720

Query: 311 TAVTAIGRVNASKGF----------------GHIWL-DSVSCQGHEPAVWQCKHHEWGK 352
                +G  N+SK                  GH+ L  S  C        QC H   GK
Sbjct: 721 -----LGSGNSSKPIFSTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGK 774



 Score = 33.9 bits (76), Expect = 0.89
 Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 12/82 (14%)

Query: 146 DAGVTCSDGSNLE--MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECG 203
           D  + C DGS+    +R   G    +G +  + Q  W T C +N+    ++ +C+ L  G
Sbjct: 663 DGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLG 722

Query: 204 SAVSFSGSSNFGEGSGPIWFDD 225
           S          G  S PI+  D
Sbjct: 723 S----------GNSSKPIFSTD 734



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 12/43 (27%), Positives = 21/43 (48%)

Query: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLG 93
           +R  +G    +G V  ++Q  W T C   W+ +  + +C  LG
Sbjct: 678 VRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLG 720



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 15/45 (33%), Positives = 21/45 (46%)

Query: 929 IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCG 973
           +R   G T+ +G V       W T C ++W    +  VCQ LG G
Sbjct: 678 VRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLG 722



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 6/59 (10%)

Query: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVA------LSTPGG 635
           +R  NG T   G V  +    W + C  +W  + ++ +CQ L  G         ST GG
Sbjct: 678 VRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFSTDGG 736



 Score = 30.8 bits (68), Expect = 7.5
 Identities = 15/49 (30%), Positives = 23/49 (46%)

Query: 715 ESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCG 763
           E+  +R  NG     G V    +  W T C ++W    ++ VC+ LG G
Sbjct: 674 EADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLG 722


>gi|56711322 ring finger protein 43 [Homo sapiens]
          Length = 783

 Score = 34.7 bits (78), Expect = 0.52
 Identities = 29/95 (30%), Positives = 34/95 (35%), Gaps = 6/95 (6%)

Query: 958  WDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSE 1017
            W L   Q   Q     P            G+G     E  C      L D PA       
Sbjct: 416  WGLSHLQSTSQHPAACPVPLRRARPPDSSGSG-----ESYCTERSGYLADGPASDSSSGP 470

Query: 1018 C-GHKEDAAVNCTDISVQKTPQKATTGRSSRQSSF 1051
            C G   D+ VNCTDIS+Q     ++T  SS  S F
Sbjct: 471  CHGSSSDSVVNCTDISLQGVHGSSSTFCSSLSSDF 505


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,852,601
Number of Sequences: 37866
Number of extensions: 2487986
Number of successful extensions: 6800
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 5182
Number of HSP's gapped (non-prelim): 397
length of query: 1121
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1008
effective length of database: 13,968,660
effective search space: 14080409280
effective search space used: 14080409280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.