Guide to the Human Genome
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Name: ERBB2 Sequence: fasta or formatted (1255aa) NCBI GI: 54792096
Description:

erbB-2 isoform a

Referenced in:

Common Drug Targets
Epidermal Growth Factor
Leucine-rich Repeat Family
PDZ Domain

Other entries for this name:
alt prot [1225aa] erbB-2 isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6         83           2
 C cysteine            4.7         59           2
 D aspartate           5.2         65           3
 E glutamate           6.1         77           3
 F phenylalanine       2.8         35           2
 G glycine             8.0        101           3
 H histidine           2.8         35           2
 I isoleucine          3.5         44           2
 K lysine              3.1         39           2
 L leucine            11.0        138           3
 M methionine          1.8         23           1
 N asparagine          3.3         41           2
 P proline             8.7        109           3
 Q glutamine           4.9         62           2
 R arginine            5.7         71           3
 S serine              5.8         73           3
 T threonine           5.3         67           2
 V valine              6.6         83           3
 W tryptophan          1.2         15           1
 Y tyrosine            2.8         35           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   erbB-2 isoform a 
ERBB2                 0.977   erbB-2 isoform b 
EGFR                  0.450   epidermal growth factor receptor isoform a precursor...
ERBB4                 0.428   v-erb-a erythroblastic leukemia viral oncogene homo...
ERBB4                 0.425   v-erb-a erythroblastic leukemia viral oncogene homolo...
ERBB3                 0.344   erbB-3 isoform 1 precursor 
EGFR                  0.213   epidermal growth factor receptor isoform d precursor...
EGFR                  0.213   epidermal growth factor receptor isoform b precursor...
EGFR                  0.130   epidermal growth factor receptor isoform c precursor...
EPHA2                 0.073   ephrin receptor EphA2 
EPHB4                 0.073   EPH receptor B4 precursor 
EPHB1                 0.071   ephrin receptor EphB1 precursor 
EPHA5                 0.070   ephrin receptor EphA5 isoform b precursor 
PTK2                  0.070   PTK2 protein tyrosine kinase 2 isoform b 
PTK2                  0.070   PTK2 protein tyrosine kinase 2 isoform a 
PTK2B                 0.069   PTK2B protein tyrosine kinase 2 beta isoform a [Homo...
PTK2B                 0.069   PTK2B protein tyrosine kinase 2 beta isoform b [Homo...
PTK2B                 0.069   PTK2B protein tyrosine kinase 2 beta isoform a [Homo...
PTK2B                 0.069   PTK2B protein tyrosine kinase 2 beta isoform a [Homo...
EPHA5                 0.069   ephrin receptor EphA5 isoform a precursor 
EPHB2                 0.068   ephrin receptor EphB2 isoform 2 precursor 
EPHA4                 0.068   ephrin receptor EphA4 
EPHB3                 0.068   ephrin receptor EphB3 precursor 
EPHB2                 0.068   ephrin receptor EphB2 isoform 1 precursor 
TNK2                  0.068   tyrosine kinase, non-receptor, 2 isoform 1 
TNK2                  0.068   tyrosine kinase, non-receptor, 2 isoform 2 
ABL2                  0.068   arg tyrosine kinase isoform c 
ABL2                  0.068   arg tyrosine kinase isoform b 
ABL2                  0.068   arg tyrosine kinase isoform d 
ABL2                  0.068   arg tyrosine kinase isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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