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Search of human proteins with 40353729
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40353729 Ras and Rab interactor 3 [Homo sapiens]
(985 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40353729 Ras and Rab interactor 3 [Homo sapiens] 1988 0.0
gi|18466802 Ras and Rab interactor 2 [Homo sapiens] 323 4e-88
gi|68989256 ras inhibitor RIN1 [Homo sapiens] 164 4e-40
gi|38348206 Ras and Rab interactor-like [Homo sapiens] 130 5e-30
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 87 8e-17
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 84 5e-16
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 83 1e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 79 3e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 78 5e-14
gi|150170670 piccolo isoform 2 [Homo sapiens] 76 1e-13
gi|150378539 piccolo isoform 1 [Homo sapiens] 76 1e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni... 75 2e-13
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 75 3e-13
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 75 3e-13
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 75 3e-13
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 75 3e-13
gi|47132519 Ras association and pleckstrin homology domains 1 is... 74 7e-13
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 73 1e-12
gi|146134388 YLP motif containing 1 [Homo sapiens] 71 4e-12
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 70 1e-11
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 69 2e-11
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 69 2e-11
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 69 3e-11
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 68 4e-11
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 68 4e-11
gi|116284392 mucin 2 precursor [Homo sapiens] 68 5e-11
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 67 8e-11
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 66 1e-10
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 66 1e-10
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 66 2e-10
>gi|40353729 Ras and Rab interactor 3 [Homo sapiens]
Length = 985
Score = 1988 bits (5151), Expect = 0.0
Identities = 985/985 (100%), Positives = 985/985 (100%)
Query: 1 MIRHAGAPARGDPTGPVPVVGKGEEEEEEDGMRLCLPANPKNCLPHRRGISILEKLIKTC 60
MIRHAGAPARGDPTGPVPVVGKGEEEEEEDGMRLCLPANPKNCLPHRRGISILEKLIKTC
Sbjct: 1 MIRHAGAPARGDPTGPVPVVGKGEEEEEEDGMRLCLPANPKNCLPHRRGISILEKLIKTC 60
Query: 61 PVWLQLSLGQAEVARILHRVVAGMFLVRRDSSSKQLVLCVHFPSLNESSAEVLEYTIKEE 120
PVWLQLSLGQAEVARILHRVVAGMFLVRRDSSSKQLVLCVHFPSLNESSAEVLEYTIKEE
Sbjct: 61 PVWLQLSLGQAEVARILHRVVAGMFLVRRDSSSKQLVLCVHFPSLNESSAEVLEYTIKEE 120
Query: 121 KSILYLEGSALVFEDIFRLIAFYCVSRDLLPFTLRLPQAILEASSFTDLETIANLGLGFW 180
KSILYLEGSALVFEDIFRLIAFYCVSRDLLPFTLRLPQAILEASSFTDLETIANLGLGFW
Sbjct: 121 KSILYLEGSALVFEDIFRLIAFYCVSRDLLPFTLRLPQAILEASSFTDLETIANLGLGFW 180
Query: 181 DSSLNPPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFI 240
DSSLNPPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFI
Sbjct: 181 DSSLNPPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFI 240
Query: 241 EDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVL 300
EDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVL
Sbjct: 241 EDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVL 300
Query: 301 PALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMK 360
PALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMK
Sbjct: 301 PALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMK 360
Query: 361 PGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSD 420
PGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSD
Sbjct: 361 PGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSD 420
Query: 421 GPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLEN 480
GPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLEN
Sbjct: 421 GPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLEN 480
Query: 481 AELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLGV 540
AELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLGV
Sbjct: 481 AELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLGV 540
Query: 541 SVMATDQDSYSTSSTEEELEQFSSPSVKKKPSMILGKARHRLSFASFSSMFHAFLSNNRK 600
SVMATDQDSYSTSSTEEELEQFSSPSVKKKPSMILGKARHRLSFASFSSMFHAFLSNNRK
Sbjct: 541 SVMATDQDSYSTSSTEEELEQFSSPSVKKKPSMILGKARHRLSFASFSSMFHAFLSNNRK 600
Query: 601 LYKKVVELAQDKGSYFGSLVQDYKVYSLEMMARQTSSTEMLQEIRTMMTQLKSYLLQSTE 660
LYKKVVELAQDKGSYFGSLVQDYKVYSLEMMARQTSSTEMLQEIRTMMTQLKSYLLQSTE
Sbjct: 601 LYKKVVELAQDKGSYFGSLVQDYKVYSLEMMARQTSSTEMLQEIRTMMTQLKSYLLQSTE 660
Query: 661 LKALVDPALHSEEELEAIVESALYKCVLKPLKEAINSCLHQIHSKDGSLQQLKENQLVIL 720
LKALVDPALHSEEELEAIVESALYKCVLKPLKEAINSCLHQIHSKDGSLQQLKENQLVIL
Sbjct: 661 LKALVDPALHSEEELEAIVESALYKCVLKPLKEAINSCLHQIHSKDGSLQQLKENQLVIL 720
Query: 721 ATTTTDLGVTTSVPEVPMMEKILQKFTSMHKAYSPEKKISILLKTCKLIYDSMALGNPGK 780
ATTTTDLGVTTSVPEVPMMEKILQKFTSMHKAYSPEKKISILLKTCKLIYDSMALGNPGK
Sbjct: 721 ATTTTDLGVTTSVPEVPMMEKILQKFTSMHKAYSPEKKISILLKTCKLIYDSMALGNPGK 780
Query: 781 PYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPALQLGEGSYYLTTTYGALEHIKSY 840
PYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPALQLGEGSYYLTTTYGALEHIKSY
Sbjct: 781 PYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPALQLGEGSYYLTTTYGALEHIKSY 840
Query: 841 DKITVTRQLSVEVQDSIHRWERRRTLNKARASRSSVQDFICVSYLEPEQQARTLASRADT 900
DKITVTRQLSVEVQDSIHRWERRRTLNKARASRSSVQDFICVSYLEPEQQARTLASRADT
Sbjct: 841 DKITVTRQLSVEVQDSIHRWERRRTLNKARASRSSVQDFICVSYLEPEQQARTLASRADT 900
Query: 901 QAQALCAQCAEKFAVERPQAHRLFVLVDGRCFQLADDALPHCIKGYLLRSEPKRDFHFVY 960
QAQALCAQCAEKFAVERPQAHRLFVLVDGRCFQLADDALPHCIKGYLLRSEPKRDFHFVY
Sbjct: 901 QAQALCAQCAEKFAVERPQAHRLFVLVDGRCFQLADDALPHCIKGYLLRSEPKRDFHFVY 960
Query: 961 RPLDGGGGGGGGSPPCLVVREPNFL 985
RPLDGGGGGGGGSPPCLVVREPNFL
Sbjct: 961 RPLDGGGGGGGGSPPCLVVREPNFL 985
>gi|18466802 Ras and Rab interactor 2 [Homo sapiens]
Length = 895
Score = 323 bits (829), Expect = 4e-88
Identities = 207/573 (36%), Positives = 304/573 (53%), Gaps = 34/573 (5%)
Query: 414 PPQGTSDGPEDTPRESTEQGQDT--EVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLA 471
PP + +PR + + Q + E + H LP T K P+PPPR K+ + L
Sbjct: 311 PPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGT-KPTPIPPPRLKKQASFLE 369
Query: 472 STLPAPLENAELCTQAMALETPTPGPPREGQSPASQAG--TQHPPAQATAHSQSSPEFKG 529
+ A + LE T G P G P + G T+ PP S+S P G
Sbjct: 370 AEGGAKTLSGGRPGAGPELELGTAGSPG-GAPPEAAPGDCTRAPPPS----SESRPPCHG 424
Query: 530 SLASLSDSLGVSVMATDQDSYSTS--------STEEELEQFSSPS-----------VKKK 570
LSD + +S ++D + S T LE + S KK+
Sbjct: 425 GRQRLSD-MSISTSSSDSLEFDRSMPLFGYEADTNSSLEDYEGESDQETMAPPIKSKKKR 483
Query: 571 PSMILGKARHRLSFASFSSMFHAFLSNNRKLYKKVVELAQDKGSYFGSLVQDYKVYSLEM 630
S + + S +F +F++ +++ +++ EL++DK +YFG LVQDY + E
Sbjct: 484 SSSFVLPKLVKSQLQKVSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLQEN 543
Query: 631 MARQTSSTEMLQEIRTMMTQLKSYLLQSTELKALVDPALHSEEELEAIVESALYKCVLKP 690
SST+MLQ IR MTQ+K+YL QS+EL ++ +L E++++ ++E A++KC+LKP
Sbjct: 544 KECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIE-SLIPEDQIDVVLEKAMHKCILKP 602
Query: 691 LKEAINSCLHQIHSKDGSLQQLKENQLVILATTTTDLGVTTSVPEVPMMEKILQKFTSMH 750
LK + + L H DGS +QLKEN ++ +LGV P+ +EKI KF +M
Sbjct: 603 LKGHVEAMLKDFHMADGSWKQLKENLQLVRQRNPQELGVFAPTPDFVDVEKIKVKFMTMQ 662
Query: 751 KAYSPEKKISILLKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYM 810
K YSPEKK+ +LL+ CKLIY M N G+ YGADDFLPVL YV+A+ ++ E+ +EYM
Sbjct: 663 KMYSPEKKVMLLLRVCKLIYTVME-NNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYM 721
Query: 811 MELMDPALQLGEGSYYLTTTYGALEHIKSYDKITVTRQLSVEVQDSIHRWERRRTLNKAR 870
MEL+DP+L GEG YYLT+ YGAL IK++ + R LS E +D++ +W +RRT N+
Sbjct: 722 MELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSETRDTLRQWHKRRTTNRTI 781
Query: 871 ASRSSVQDFICVSYLEPEQ--QARTLASRADTQAQALCAQCAEKFAVERPQAHRLFVLVD 928
S Q+++ V++ E +TL R + +C CAEKF V P+ + LF+ VD
Sbjct: 782 PSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQICAEKFKVGDPEEYSLFLFVD 841
Query: 929 GRCFQLADDALPHCIKGYLLRSEPKRDFHFVYR 961
QLA+D P IK L FHFVY+
Sbjct: 842 ETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYK 874
Score = 154 bits (389), Expect = 4e-37
Identities = 147/467 (31%), Positives = 210/467 (44%), Gaps = 71/467 (15%)
Query: 28 EEDGMRLCLPANPKNCLPHRRGISILEKLIKTCPVWLQLSLGQAEVARILHRVVAGMFLV 87
EE+ ++ C + + L +R +SIL++L+ T P+WLQLSL + E A +L G+FLV
Sbjct: 64 EEEDVKTCARDSGYDSLSNR--LSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFLV 121
Query: 88 RRDSSSKQLVLCVHFPSLNESSAEVLEYTIKEEKSILYLEGSALVFEDIFRLIAFYCVSR 147
+ + ++ VL + P E A + E+ IKE LEGS + F D+FRLIAFYC+SR
Sbjct: 122 HKSTKMQKKVLSLRLPC--EFGAPLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISR 179
Query: 148 DLLPFTLRLPQAILEASSFTDLETIANLGLGFWDSSLNPPQERGKPAEPPRDRAPGFPLV 207
D+LPFTL+LP AI A S LE +A +GL FW S P + P PP R V
Sbjct: 180 DVLPFTLKLPYAISTAKSEAQLEELAQMGLNFWSS----PADSKPPNLPPPHRPLSSDGV 235
Query: 208 --SSLRPT-------AHDANCACEIELSVGNDRLWFVNPIFI----EDCSSAL--PTDQP 252
+SLR + E+E S N L F+NP+F+ +D S L P+ +
Sbjct: 236 CPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSGGLKRPSTRT 295
Query: 253 PLGNCPARPLPPTSDATSPTSRWAPRRPPPP-------PPVLPLQPCSPAQPPVLPALAP 305
P N R P P RPPPP P L + P +
Sbjct: 296 PNANGTERTRSP------------PPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKH 343
Query: 306 APACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCE----RLPCPTAGLGPLRE--EAM 359
LP + P P P PP Q + E L G GP E A
Sbjct: 344 GNVA-LPGTKPTPIP--------PPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAG 394
Query: 360 KPGAA---SSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQ 416
PG A ++P APP ++ P R+R+S+ +S+ S + E D+ S+P
Sbjct: 395 SPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLSD-MSISTSSSD-SLEFDR-SMPLF 451
Query: 417 G----TSDGPEDTPRESTEQGQDTEVKASDPHS----MPELPRTAKQ 455
G T+ ED ES ++ +K+ S +P+L ++ Q
Sbjct: 452 GYEADTNSSLEDYEGESDQETMAPPIKSKKKRSSSFVLPKLVKSQLQ 498
>gi|68989256 ras inhibitor RIN1 [Homo sapiens]
Length = 783
Score = 164 bits (415), Expect = 4e-40
Identities = 143/491 (29%), Positives = 225/491 (45%), Gaps = 41/491 (8%)
Query: 463 KKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQ 522
K R+S + +S L P P P P G P+ T+ P +
Sbjct: 246 KVRVSTETSSPLSPPAV------------PPPPVPVLPGAVPSQ---TERLPPCQLLRRE 290
Query: 523 SSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKKPSMILGKARHRL 582
SS ++ S SL + D S SS+EEE P + P+ R R
Sbjct: 291 SSVGYRVPAGS-GPSLPPMPSLQEVDCGSPSSSEEE----GVPGSRGSPATSPHLGRRRP 345
Query: 583 SFASFSSMFHAFLSNNRKLYKKVVELAQDKGSYFGSLVQDYKVYSLEMMARQTSSTEMLQ 642
S S+ F + L+ R++ + L QD+ + G LVQD L R + LQ
Sbjct: 346 LLRSMSAAFCSLLAPERQVGRAAAALMQDRHTAAGQLVQD-----LLTQVRAGPEPQELQ 400
Query: 643 EIRTMMTQLKSYLLQSTELKALVDPALHSEEELEAIVESALYKCVLKPLKEAINSCLHQI 702
IR +++ ++ L + L+ P + LE ++E +L+ VLKPL+ + + L +
Sbjct: 401 GIRQALSRARAMLSAELGPEKLLSP-----KRLEHVLEKSLHCSVLKPLRPILAARLRRR 455
Query: 703 HSKDGSLQQLKENQLVILATTTTDLGVTTSVPEVPMMEKILQKFTSMHKAYSPEKKISIL 762
+ DGSL +L E + A G S+P +E++ QK + + YSP ++ L
Sbjct: 456 LAADGSLGRLAEGLRLARAQGPGAFGSHLSLPSPVELEQVRQKLLQLLRTYSPSAQVKRL 515
Query: 763 LKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPALQLGE 822
L+ CKL+Y ++ G+ GAD+FLP+L VLA +L E+LL EYM EL++P+L GE
Sbjct: 516 LQACKLLYMALRT-QEGEGAGADEFLPLLSLVLAHCDLPELLLEAEYMSELLEPSLLTGE 574
Query: 823 GSYYLTTTYGALEHIKSYDKI-TVTRQLSVEVQDSIHRWERRRTLNKARASRSSVQDFIC 881
G YYLT+ +L + + T+ E++ S+ WE+RR + Q +
Sbjct: 575 GGYYLTSLSASLALLSGLGQAHTLPLSPVQELRRSLSLWEQRRL-----PATHCFQHLLR 629
Query: 882 VSYLEPEQ--QARTLASRADTQAQALCAQCAEKFAVERPQAHRLFVLVDGRCFQLADDAL 939
V+Y +P ++TLA + L CA KF V +P LF+ + +L AL
Sbjct: 630 VAYQDPSSGCTSKTLAVPPEASIATLNQLCATKFRVTQPNTFGLFLYKEQGYHRLPPGAL 689
Query: 940 PHCI--KGYLL 948
H + GYL+
Sbjct: 690 AHRLPTTGYLV 700
Score = 124 bits (310), Expect = 6e-28
Identities = 104/327 (31%), Positives = 147/327 (44%), Gaps = 45/327 (13%)
Query: 45 PHRRG--ISILEKLIKTCPVWLQLSLGQAEVARILHRVVAGMFLVRRDSSSKQLVLCVHF 102
P R G +S+ E+L+ T PVWLQL A +L G FLVR+ ++ + LC+
Sbjct: 49 PQRPGRVVSLRERLLLTRPVWLQLQANAAAALHMLRTEPPGTFLVRKSNTRQCQALCMRL 108
Query: 103 PSLNESSAEVLEYTIKEEKSILYLEGSALVFEDIFRLIAFYCVSRDLLPFTLRLPQAILE 162
P + S V + I E + LEGS L+F D+ +LI YC +RD+L L+LP+AI
Sbjct: 109 PEASGPSF-VSSHYILESPGGVSLEGSELMFPDLVQLICAYCHTRDILLLPLQLPRAIHH 167
Query: 163 ASSFTDLETIANLGLGFWDSSLNPPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACE 222
A++ +LE I++LG+ FW SSLN +RG PA G P++ L+ A E
Sbjct: 168 AATHKELEAISHLGIEFWSSSLNIKAQRG-PA--------GGPVLPQLK-----ARSPQE 213
Query: 223 IELSVGNDRLWFVNPIFIEDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPP- 281
++ G L F NP+F D LG + T +P PP
Sbjct: 214 LDQGTG-AALCFFNPLFPGD-----------LGPTKREKFKRSFKVRVSTETSSPLSPPA 261
Query: 282 -PPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMT 340
PPPPV PVLP P+ LP + + P+ PPM +
Sbjct: 262 VPPPPV-----------PVLPGAVPSQTERLPPCQLLRRESSVGYRVPAGSGPSLPPMPS 310
Query: 341 CERLPCPTAGLGPLREEAMKPGAASSP 367
+ + C G EE PG+ SP
Sbjct: 311 LQEVDC---GSPSSSEEEGVPGSRGSP 334
>gi|38348206 Ras and Rab interactor-like [Homo sapiens]
Length = 452
Score = 130 bits (328), Expect = 5e-30
Identities = 82/243 (33%), Positives = 137/243 (56%), Gaps = 13/243 (5%)
Query: 637 STEMLQEIRTMMTQLKSYLLQSTELKALVD---PAL-HSEEELEAIVESALYKCVLKPLK 692
+TE+LQ++R ++T L+ +L + + ++A+ P L +E+ +E+A+ + VL PLK
Sbjct: 185 ATELLQDVRHLLTDLQDHLAKDSYIRAVFGSRGPGLPKKDEDPGPALETAVCQAVLAPLK 244
Query: 693 EAINSCLHQIHSKDGSLQQLKENQLVILATT----TTDLGVTTSVPEVPMMEKILQKFTS 748
A+ + L + + + L++L+ Q + A G P + +I ++
Sbjct: 245 PALWTRLRTLRAPE--LRRLRRRQTALRAGAGPPGAQGPGPEGQSPAPALRSRIHERLAH 302
Query: 749 MHKAYSPEKKISILLKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARS-NLTEMLLNV 807
+H A +P +K+++LL+ C+ +Y +A G P GAD FLP L L S ++ + L+V
Sbjct: 303 LHAACAPRRKVALLLEVCRDVYAGLARGENQDPLGADAFLPALTEELIWSPDIGDTQLDV 362
Query: 808 EYMMELMDPALQLGEGSYYLTTTYGALEHIKSYDKIT--VTRQLSVEVQDSIHRWERRRT 865
E++MEL+DP GE YYLTT +GAL HI Y T R LS E + S+H+W RRRT
Sbjct: 363 EFLMELLDPDELRGEAGYYLTTWFGALHHIAHYQPETDRAPRGLSSEARASLHQWHRRRT 422
Query: 866 LNK 868
L++
Sbjct: 423 LHR 425
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 87.0 bits (214), Expect = 8e-17
Identities = 126/447 (28%), Positives = 154/447 (34%), Gaps = 69/447 (15%)
Query: 157 PQAILEASSFTDLETIANLGLGFWDSSLNPPQERGKPAE---PPRDRAPGF---PLVSSL 210
PQA L + LET SSL PP + PA PP + P PL ++
Sbjct: 500 PQAPLSSLIMPPLET---------QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550
Query: 211 RP--TAHDANCACEIELSVGNDRLWFVNPIFIEDCSSALPTDQPPLGNCPARPLPPTSDA 268
P T H C + P S A P Q P PA PP
Sbjct: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP----PALASPPLQGL 606
Query: 269 TSPTSRWAPRRPPPPPPVLPLQPC-SPAQPPVLPALAPAPACPLPTSPPVPAPHV--TPH 325
SP PP PP L L P +P PP P L+P A P P +P A H+ P
Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPF 665
Query: 326 APGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTA 385
+P PP P Q P P + P P A+ PLQ P+PP +
Sbjct: 666 SP-PPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Query: 386 PPRRRVSERVSLEDQSPGMAAEGDQL-SLPPQGTSDGPEDTPRESTE---QGQDTEVKAS 441
PP P +AA Q+ PP P TP +V S
Sbjct: 722 PP----------PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771
Query: 442 DPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCTQAMA-----LETPTPG 496
P S+P P AK PP PP Q + PA + + + L TP P
Sbjct: 772 PPASLPMSP-LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830
Query: 497 ------------PPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLA-------SLSDS 537
PP SP QA + PP S S P +LA S S S
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQA-PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 889
Query: 538 LGVSVMATDQDSYSTSSTEEELEQFSS 564
+S S S +ST EEL + S
Sbjct: 890 STLSGPDLAGHSSSATSTPEELRGYDS 916
Score = 82.0 bits (201), Expect = 2e-15
Identities = 87/289 (30%), Positives = 114/289 (39%), Gaps = 41/289 (14%)
Query: 248 PTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQ--PCSPAQPPVLPALAP 305
P PP A PP S SP++ P + PP PLQ P PA PP+ P+ P
Sbjct: 664 PFSPPPSPPVQAPFSPPASPPVSPSAT-PPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722
Query: 306 APACP---------LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERL---PCPTAGL-- 351
P P +P SPP +P ++P A P P PP++ L P P A L
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPA-SPPMSPSATPP---PRVPPLLAAPPLQVPPSPPASLPM 778
Query: 352 GPLREEAMK--PGAASSPLQQVPAPPLPAKKNLPTAPPRR-RVSERVSLEDQSPGMAAEG 408
PL + + P A+ PLQ +P+PP P +P +S + Q+P + A
Sbjct: 779 SPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA-A 837
Query: 409 DQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISR 468
L +PP + PR G DT V S P L P PPP SR
Sbjct: 838 PLLQVPPSPPASPTLQAPRRPPTPGPDTSV------SGPRLTLALAPGPPPPP-----SR 886
Query: 469 QLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQA 517
+STL P +L + + T TP R S PP A
Sbjct: 887 SPSSTLSGP----DLAGHSSS-ATSTPEELRGYDSGPEGGAAASPPPDA 930
Score = 81.6 bits (200), Expect = 3e-15
Identities = 98/342 (28%), Positives = 127/342 (37%), Gaps = 75/342 (21%)
Query: 244 SSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVL--PLQ--PCSPAQPPV 299
S+ P+ PP P +PP+ A+ P S A P PPP+ PLQ P PA PP+
Sbjct: 688 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM 747
Query: 300 LPALAPAPACP---------LPTSPPVPAPHVTPHAPGPPDHPNQ---PPMMTCERLPCP 347
P+ P P P +P SPP P ++P A PP P PP+ P
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASLP-MSPLAKPPPQAPPALATPPLQALPSPPAS 806
Query: 348 TAGLGPLREEA------------MKPGAASSPLQQVP-----APPLPAKKNLPTAPPRRR 390
G P A P ++PL QVP +P L A + PT P
Sbjct: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866
Query: 391 VS-ERVSLE---------DQSPGMAAEGDQLSLPPQGTSDGPEDTPRE--STEQGQDTEV 438
VS R++L +SP G L+ G S TP E + G +
Sbjct: 867 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA----GHSSSATSTPEELRGYDSGPEGGA 922
Query: 439 KASDPHSMPELPRTAKQP------PVPPPRKKRISRQLASTLPAPLENAE-------LCT 485
AS P P+ A P P PP ++ + A P P A LCT
Sbjct: 923 AASPP---PDAELAACHPAAWSRGPAPP-----LAFRGAPGAPLPWPPATGPGSADGLCT 974
Query: 486 ----QAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQS 523
+ TP PG G SP + G A A A S+S
Sbjct: 975 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 1016
Score = 80.1 bits (196), Expect = 9e-15
Identities = 107/406 (26%), Positives = 145/406 (35%), Gaps = 65/406 (16%)
Query: 154 LRLPQAILEASSFTDLETIANLGLGFWDSSLNPPQERGKPAEPPRDRAPGFPLVSSLRPT 213
L+ P + +SS T L + A G P RG P P P + +LRP
Sbjct: 234 LQRPASRSLSSSATPLSSPARSG----------PSARGTPRAPAHPSQPKPKGLQALRPP 283
Query: 214 AHDANCACEIELSVGNDRLWFVNPIFIEDCSSALPTDQPPLGNCPARPLPPTSDATSPTS 273
D + P+ S+ P P ARP+PP +A +P
Sbjct: 284 Q---------VTPPRKDAAPALGPL------SSSPLATPSPSGTKARPVPPPDNAATPL- 327
Query: 274 RWAPRRPPPPPPV---LPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPP 330
P PP PP+ LPL P SP+ PP L L PA P +PP TP PP
Sbjct: 328 ---PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP---SMTTPPMQAPP 381
Query: 331 DHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASS--PLQQVPAPPLPAKKNLPTAPPR 388
PP+ L P+ P P A SS + +P L A + T PR
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPP------SPLALSSLQATTSLGSPTLQATHSFLTMSPR 435
Query: 389 R------RVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASD 442
+ S S SP + A + PP TS P +P S + +S
Sbjct: 436 QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSL 495
Query: 443 PHSMPELPRTA-------KQPPVPPPRKKRIS--------RQLASTLPAPLENAELCTQA 487
P+ P ++ Q + PP + L S P PL+ A
Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT 555
Query: 488 MALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLAS 533
LETP P Q+P S T PP ++ + P+ +LAS
Sbjct: 556 PHLETPPCPAPCPLQAPPSPL-TTPPPETPSSIATPPPQAPPALAS 600
Score = 40.0 bits (92), Expect = 0.011
Identities = 66/281 (23%), Positives = 94/281 (33%), Gaps = 47/281 (16%)
Query: 302 ALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKP 361
A AP P P P P P VTP A G PL E A
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLG-------------AAGAVGRKPLAERAGGI 65
Query: 362 GAASSPLQQVPAPPL----PAKKNLPTAPPRRRVSERV-SLEDQSPGMAAEGDQLS---L 413
G A+ P A P + +N + PP ER ++ SPG + + S
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
Query: 414 PPQGTSDGPEDTPRESTEQGQDTEV-KASDPHSMPELPRTAKQPPVPPPRKKRISRQLAS 472
P G + E+ +G+ TE K S + + P P P R SR +
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
Query: 473 T--LPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGS 530
LP P +A P PP EG + + ++H + + ++ P
Sbjct: 186 EVGLPRPAPSAR------------PRPPTEGPRKSVSSASEHSTTEPSPAARRRP----- 228
Query: 531 LASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKKP 571
S G + S S+S+T S PS + P
Sbjct: 229 ------SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
Score = 38.1 bits (87), Expect = 0.041
Identities = 69/299 (23%), Positives = 100/299 (33%), Gaps = 44/299 (14%)
Query: 277 PRRPPPPPPVLP--LQPCSPA----QPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPP 330
P P PPPPV P L+ A + P+ +P S P P +
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
Query: 331 DHPNQPPMMTCERL-PCPTAGLGPLREE-----AMKPGAASSPLQQVPAPPLPAKKNLPT 384
P ER P GP+ +PG ++ A A+
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
Query: 385 APPR-------RRVSERVSLEDQSPGMA----AEGDQLSLPPQGTSDGPEDTPRESTEQG 433
AP R RR + + SP MA A G ++ LP P PR TE
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP----RPAPSARPRPPTEGP 205
Query: 434 QDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCTQAMALETP 493
+ + AS+ + P ++P ++ SR L+S+ A L +P
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS-------------ATPLSSP 252
Query: 494 TPGPPREGQSPASQAGTQHPP---AQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDS 549
P +P + A P QA Q +P K + +L L S +AT S
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG-PLSSSPLATPSPS 310
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 84.3 bits (207), Expect = 5e-16
Identities = 81/306 (26%), Positives = 112/306 (36%), Gaps = 36/306 (11%)
Query: 240 IEDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQ--- 296
++ + +P PP P P PP P PPPPPP +P Q +PA
Sbjct: 746 MQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPP--------PPPPPPSMP-QQAAPAMKSS 796
Query: 297 -PPVLPALAPAPACPLP----------TSP--PVPAPHVTPHAPGPPDHPNQPPMMTCER 343
PP + P LP T P +P P + PH P PP+H + PP +
Sbjct: 797 PPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEH-STPPHLNQHA 855
Query: 344 LPCPTAGLGPLREEAMKPGAASSPLQQVPAPP---LPAKKNLPTAP-PRRRVSERVSLED 399
+ P A L ++ +P ++ L PA P PA P P P +V LED
Sbjct: 856 VVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLED 915
Query: 400 Q---SPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQP 456
+ +P + + QL L P Q Q PH + + P
Sbjct: 916 EEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPP 975
Query: 457 PVPPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQ 516
P PPP+ + +Q P P+ L + P PP+ Q P G Q PP Q
Sbjct: 976 PPPPPQPQPPPQQQHQPPPRPV---HLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQ 1032
Query: 517 ATAHSQ 522
Q
Sbjct: 1033 PAKPQQ 1038
Score = 55.1 bits (131), Expect = 3e-07
Identities = 43/145 (29%), Positives = 59/145 (40%), Gaps = 16/145 (11%)
Query: 262 LPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVL----PALAPAPACPLPTSPPV 317
+P T+ A++P P+ P PPPV PA P L P + P PL T PPV
Sbjct: 196 VPNTTQASTPPQTQTPQ--PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPV 253
Query: 318 PAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPA-PPL 376
P P AP P + PP++ P T G R+ P+ + P+ PP
Sbjct: 254 PPQPQPPPAPAPQPVQSHPPIIAATPQPVKTK-KGVKRKADTTTPTTIDPIHEPPSLPPE 312
Query: 377 PAKKNL--------PTAPPRRRVSE 393
P L P PP++ V +
Sbjct: 313 PKTTKLGQRRESSRPVKPPKKDVPD 337
Score = 49.3 bits (116), Expect = 2e-05
Identities = 85/358 (23%), Positives = 114/358 (31%), Gaps = 45/358 (12%)
Query: 248 PTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPV-----LPLQPCSPAQPP--VL 300
P P L P P PP A P PP PP L LQ QPP +L
Sbjct: 888 PAVSPALTQTPLLPQPPM--AQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLL 945
Query: 301 PALA----PAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLR- 355
P++ P P P P P V P PP P PP + P P L P++
Sbjct: 946 PSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRP-VHLQPMQF 1004
Query: 356 ----EEAMKPGAASSPLQ---QVPAPPLPAKKNLPTA---PPRRRVSERVS---LEDQSP 402
++ P P Q P PP PAK PR S+ S L +
Sbjct: 1005 STHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPS 1064
Query: 403 GMAAEGDQLSL---------PPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTA 453
+ Q+S P Q ++ S Q Q V + P +
Sbjct: 1065 PLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEP 1124
Query: 454 KQPPV-PPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQH 512
P + P P K S + LP E + + P P G +P Q
Sbjct: 1125 FSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPG-APDKDKQKQE 1183
Query: 513 PPAQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKK 570
P + GS ASL + +T S+ + EQF + +K+
Sbjct: 1184 PKTPVAPKKDLKIKNMGSWASLVQKHPTTPSST------AKSSSDSFEQFRRAAREKE 1235
Score = 30.4 bits (67), Expect = 8.5
Identities = 48/200 (24%), Positives = 67/200 (33%), Gaps = 27/200 (13%)
Query: 334 NQPPMMTCERLPCPTAGLGPLREEA--MKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRV 391
N+ P E + G G R+E KPG ++ P + P + P PP +
Sbjct: 162 NELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQAT 221
Query: 392 SERV-----SLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSM 446
L Q+P M +PPQ P TP Q Q A P +
Sbjct: 222 PHPFPAVTPDLIVQTPVMTV------VPPQ-----PLQTPPPVPPQPQPPPAPAPQP--V 268
Query: 447 PELPRTAKQPPVPPPRKKRISRQLASTLPAPLENA-ELCTQAMALETPTPGPPREGQSPA 505
P P P KK + R+ +T P ++ E + +T G RE P
Sbjct: 269 QSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPV 328
Query: 506 SQAGTQHPPAQATAHSQSSP 525
PP + SQ P
Sbjct: 329 K------PPKKDVPDSQQHP 342
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 83.2 bits (204), Expect = 1e-15
Identities = 102/367 (27%), Positives = 136/367 (37%), Gaps = 56/367 (15%)
Query: 184 LNPPQERGKPAEPPRDRAPGFPL--VSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIE 241
L PP+E P PP + +P P S L P E+ S + L P+ E
Sbjct: 441 LPPPEE--SPLSPPPEESPTSPPPEASRLSPPPE------ELPASPLPEALHLSRPL--E 490
Query: 242 DCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPP---PPPPVL--PLQP---CS 293
+ + P ++ PL PP S SP +P PP PP P L PL P S
Sbjct: 491 ESPLSPPPEESPLSP------PPESSPFSPLEE-SPLSPPEESPPSPALETPLSPPPEAS 543
Query: 294 PAQPPVLPALAPAPACPLPTSPP------VPAPHVTPHAPGPPDHPNQPPMMTCERLPCP 347
P PP + P LPTSPP P P +P +P P + P PP P
Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFP-- 601
Query: 348 TAGLGPLREEAMKPGAASSPLQQVPAPP--LPAKKNLPTAPPRRRVSERVSLEDQSPGMA 405
P E + P SPL P P ++ P +PP E
Sbjct: 602 -----PFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL 656
Query: 406 AEGDQLSLPPQGT--SDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRK 463
+LS PP+ + S PE++P T + + P P P P PPP
Sbjct: 657 PVVSRLSPPPEESPLSPPPEESP---TSPPPEASRLSPPPEDSPTSPPPEDSPASPPPED 713
Query: 464 KRISRQLAST--LPAPLENAELCTQAMALETP--TPGPPREGQSPASQAGTQHPPAQATA 519
+S L + LP P E +LC ++ E P +P P SP + P A+
Sbjct: 714 SLMSLPLEESPLLPLP-EEPQLCPRS---EGPHLSPRPEEPHLSPRPEEPHLSPQAE-EP 768
Query: 520 HSQSSPE 526
H PE
Sbjct: 769 HLSPQPE 775
Score = 65.5 bits (158), Expect = 2e-10
Identities = 98/367 (26%), Positives = 138/367 (37%), Gaps = 61/367 (16%)
Query: 179 FWDSSLNPPQERGKPAEPPR-DRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNP 237
F +S L+PP E + PP R P S + P ++ + E S RL+ P
Sbjct: 549 FEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEAS----RLF---P 601
Query: 238 IFIEDCSSALPTDQPPLGNCP--ARPLPPTSDAT-SPTSRWAPRRPPP------------ 282
F E+ + P ++ PL P +R PP D+ SP +P PPP
Sbjct: 602 PF-EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660
Query: 283 ----PPPVLPLQPC---SPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQ 335
PP PL P SP PP + P PTSPP P +P +P P D
Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPP---PEDSPASPPPEDSLMS 717
Query: 336 PPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPP-LPAKKNLPTAPPRRRVSER 394
P+ LP P E + P + L P P L + P P+
Sbjct: 718 LPLEESPLLPLP-------EEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAE-EPH 769
Query: 395 VSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAK 454
+S + + P + A ++ L PQ ++GP +P Q E+ S P L +
Sbjct: 770 LSPQPEEPCLCAVPEEPHLSPQ--AEGPHLSP-------QPEELHLSPQTEEPHLSPVPE 820
Query: 455 QPPV-PPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPRE------GQSPASQ 507
+P + P P + +S Q S P E + LE P P E GQ PA +
Sbjct: 821 EPCLSPQPEESHLSPQ--SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPE 878
Query: 508 AGTQHPP 514
PP
Sbjct: 879 ELPLFPP 885
Score = 60.8 bits (146), Expect = 6e-09
Identities = 93/371 (25%), Positives = 134/371 (36%), Gaps = 45/371 (12%)
Query: 162 EASSFTDLETIANLGLGFWDSSLNPPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCAC 221
E S + L ++ L +S L+PP E P PP P S L P D+ +
Sbjct: 649 EVSRLSPLPVVSRLSPPPEESPLSPPPEE-SPTSPP-------PEASRLSPPPEDSPTSP 700
Query: 222 EIELSVGNDRLWFVNPIFIEDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPP 281
E S + ED +LP ++ PL P P P S P
Sbjct: 701 PPEDSPASPP--------PEDSLMSLPLEESPLLPLPEEP------QLCPRSEGPHLSPR 746
Query: 282 PPPPVLPLQPCSPAQPPVL--PALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMM 339
P P L +P P P P L+P P P + P PH++P A GP P +
Sbjct: 747 PEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP-EEPHLSPQAEGPHLSPQPEELH 805
Query: 340 TCERLPCPTAGLGPLREE-AMKPGAAS---SPLQQVPA-PPLPAKKNLPTAPPRRRVSER 394
+ P L P+ EE + P SP + P P P + +L + +S R
Sbjct: 806 LSPQTEEP--HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPR 863
Query: 395 VSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAK 454
+ PG ++L L P P P S G+ + +P P LP +
Sbjct: 864 PEKPPEEPGQCPAPEELPLFP------PPGEPSLSPLLGEPALSEPGEPPLSP-LP---E 913
Query: 455 QPPVPPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPP 514
+ P+ P + +S QL P P + + T A P P E + P G P
Sbjct: 914 ELPLSPSGEPSLSPQLMPPDPLPPPLSPIIT---AAAPPALSPLGELEYPFGAKGDSDPE 970
Query: 515 AQATAHSQSSP 525
+ A +P
Sbjct: 971 SPLAAPILETP 981
Score = 56.6 bits (135), Expect = 1e-07
Identities = 89/350 (25%), Positives = 118/350 (33%), Gaps = 78/350 (22%)
Query: 247 LPTDQPPLGNCPARPLP------PTSDATSPTSRWAPRRPP---------PPPPVLPLQP 291
+P LG+ P P PT+ A TS +PP P L L P
Sbjct: 2106 IPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPP 2165
Query: 292 CSPAQPPVLPALAPAPACPL----PTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLP-- 345
PAQ P APA PL PT+PP P+ P P P QPPM+ P
Sbjct: 2166 QVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPY-----PSPTGAPAQPPMLGASSRPGA 2220
Query: 346 -----CPTAGLGPLREEAMKPGAASSP----LQQVPAPPLP----AKKNLPTAPPRRRVS 392
T G R + P P L + P P K + P P
Sbjct: 2221 GQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE 2280
Query: 393 ERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRT 452
R +LE + + A P G D+P T G E+K D P PR
Sbjct: 2281 SRKALEVKKEELGASSPSYGPPNLGF----VDSPSSGTHLG-GLELKTPDVFKAPLTPRA 2335
Query: 453 AKQPPVPP-----PRKKRISRQLASTLPA------PLENAELCTQAMALETPTPGPP--- 498
++ P P P++ ++ LA + P+ P + Q P P PP
Sbjct: 2336 SQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESC 2395
Query: 499 --------------REGQSPASQAGTQHP------PAQATAHSQSSPEFK 528
R SP SQ+ +Q P A+A S +P F+
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ 2445
Score = 56.2 bits (134), Expect = 1e-07
Identities = 70/285 (24%), Positives = 100/285 (35%), Gaps = 28/285 (9%)
Query: 248 PTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPV-LPLQPCSPAQPPVLPALAPA 306
PTD+P + P TS +P P P+ +P A + P L
Sbjct: 381 PTDEPDALYVACQGQPKGGHVTS-------MQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433
Query: 307 PACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASS 366
+P PP P +P +P P + P PP P P EA+ S
Sbjct: 434 LNEEMPLLPP---PEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALH---LSR 487
Query: 367 PLQQVPAPPLPAKKNL---PTAPPRRRVSER-VSLEDQSPGMAAEGDQLSLPPQGT---- 418
PL++ P P P + L P + P + E +S ++SP A LS PP+ +
Sbjct: 488 PLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP 547
Query: 419 --SDGPEDTPRESTEQGQDTEVK--ASDPHSMPELPRTAKQPPVPPPRKKRISRQL-AST 473
+ P P E E + P P P + P PPP R+ S
Sbjct: 548 PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP 607
Query: 474 LPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQAT 518
L P E + L A +P P SP + PP + +
Sbjct: 608 LSPPPEESPLSPPPEASRL-SPPPEDSPMSPPPEESPMSPPPEVS 651
Score = 51.6 bits (122), Expect = 4e-06
Identities = 57/194 (29%), Positives = 70/194 (36%), Gaps = 30/194 (15%)
Query: 251 QPPLGNCPARPLPPTSD-ATSPTSRWAPRRPPPPP---------PVLPLQPCSPAQPPVL 300
QP LG P P + P + PR P PP PV P P S Q P
Sbjct: 4260 QPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKR 4319
Query: 301 PALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTA------GLGPL 354
P+ P+P+ LPT +P H P P P +PP A GLGP
Sbjct: 4320 PSQLPSPSSQLPTEAQLPPTH--PGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPW 4377
Query: 355 -----REEAMKPGAAS---SPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAA 406
E KP +S L QV +P L R E +L QS A
Sbjct: 4378 DPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPR--EEPCALGAQSVKREA 4435
Query: 407 EGDQLSLPPQGTSD 420
G+ + P GTS+
Sbjct: 4436 NGEPIGAP--GTSN 4447
Score = 48.5 bits (114), Expect = 3e-05
Identities = 85/364 (23%), Positives = 126/364 (34%), Gaps = 67/364 (18%)
Query: 248 PTDQPPLGNCPAR---PL--PPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPA 302
P ++P G CPA PL PP + SP P PP+ PL P P P+
Sbjct: 867 PPEEP--GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPS 924
Query: 303 LAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLG---------- 352
L+P P P PP+ +P +T AP P + L P G
Sbjct: 925 LSPQLMPPDPLPPPL-SPIITAAAP--------PALSPLGELEYPFGAKGDSDPESPLAA 975
Query: 353 PLREEAMKPGAASSPLQQVPAPP--LPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQ 410
P+ E + P ++ P PP LP P P + E + P + Q
Sbjct: 976 PILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPL------PPQCSPLLQ 1029
Query: 411 LSLPPQGTSDG-------PEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRK 463
SL PQ + P P + G+ V SD + E+ + V P
Sbjct: 1030 HSLVPQNSPPSQCSPPALPLSVPSPLSPIGK--VVGVSDEAELHEM----ETEKVSEPEC 1083
Query: 464 KRISRQLASTLPAPLENAELCTQAMALETPTPGPPRE-----GQSPASQAGTQHP---PA 515
+ S LP+P+ + ++ P+P P + G+ A G P P
Sbjct: 1084 PALEPSATSPLPSPMGD-------LSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPE 1136
Query: 516 QATAHSQSSPEFKGSLA-----SLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKK 570
+ E KGS L+ + V + + S EE E+ +P
Sbjct: 1137 PGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTP 1196
Query: 571 PSMI 574
P++I
Sbjct: 1197 PTLI 1200
Score = 47.0 bits (110), Expect = 9e-05
Identities = 66/289 (22%), Positives = 98/289 (33%), Gaps = 29/289 (10%)
Query: 261 PLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAP 320
PL P + P S RP PPP L P P+ P + P + P P
Sbjct: 2330 PLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFR--------PGSYTDPYAQP 2381
Query: 321 HVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKK 380
+TP P PP +C LP + P P + SS + PL A+
Sbjct: 2382 PLTP-------RPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEA 2434
Query: 381 NLPT-APPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVK 439
P+ PR + + S P L PP+ P + ++ +
Sbjct: 2435 FCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPR---PQPPEVAFKAGSLAHTSLGA 2491
Query: 440 ASDPHSMPELPR---TAKQPPVPPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPG 496
P ++P P AK P PP R S + + P QA+ + P
Sbjct: 2492 GGFPAALPAGPAGELHAKVPSGQPPNFVR-SPGTGAFVGTPSPMRFTFPQAVGEPSLKPP 2550
Query: 497 PPREGQSPASQAGTQHPPA------QATAHSQSSPEFKGSLASLSDSLG 539
P+ G P + P Q+T ++ ++ F S + L S G
Sbjct: 2551 VPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSG 2599
Score = 44.7 bits (104), Expect = 4e-04
Identities = 72/316 (22%), Positives = 105/316 (33%), Gaps = 30/316 (9%)
Query: 187 PQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSSA 246
P +P EP P P +S H + E+ LS + ++P+ E C S
Sbjct: 768 PHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP-HLSPVPEEPCLSP 826
Query: 247 LPTDQ--PPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALA 304
P + P P P SP P P P P P +P PA
Sbjct: 827 QPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP--------PEEPGQCPAPE 878
Query: 305 PAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAA 364
P P P P + +P + A P P P+ E LP +G L + M P
Sbjct: 879 ELPLFPPPGEPSL-SPLLGEPALSEPGEPPLSPLP--EELPLSPSGEPSLSPQLMPPDPL 935
Query: 365 SSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAE--GDQLSLPPQGTSDGP 422
PL + P + P + + +SP +AA +S PP+ P
Sbjct: 936 PPPLSPIITAAAPPALS-PLGELEYPFGAKGDSDPESP-LAAPILETPISPPPEANCTDP 993
Query: 423 EDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAE 482
E P + V + P M P+PP + L +P ++
Sbjct: 994 EPVPPMILPPSPGSPVGPASPILM---------EPLPPQCSPLLQHSL---VPQNSPPSQ 1041
Query: 483 LCTQAMALETPTPGPP 498
A+ L P+P P
Sbjct: 1042 CSPPALPLSVPSPLSP 1057
Score = 37.4 bits (85), Expect = 0.070
Identities = 77/300 (25%), Positives = 103/300 (34%), Gaps = 43/300 (14%)
Query: 248 PTDQPPLGNCPARPL-PPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPA 306
P PP + P PP A+S P PP P S P + P
Sbjct: 2193 PPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSL 2252
Query: 307 PACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTC--ERLPCPTAGLGPLREEAMKPGAA 364
+P SP V + PP + E L + GP G
Sbjct: 2253 DNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGP-----PNLGFV 2307
Query: 365 SSPLQQVPAPPLPAK-KNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPE 423
SP L K ++ AP R S+ +E QSPG+ Q P Q + P
Sbjct: 2308 DSPSSGTHLGGLELKTPDVFKAPLTPRASQ---VEPQSPGLGLR-PQEPPPAQALAPSPP 2363
Query: 424 DTPRESTEQGQDTEVKASDPHSMPEL-PRTAKQPPVP------PPR--------KKRISR 468
P + G T DP++ P L PR QPP P PPR + S
Sbjct: 2364 SHP-DIFRPGSYT-----DPYAQPPLTPR--PQPPPPESCCALPPRSLPSDPFSRVPASP 2415
Query: 469 QLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFK 528
Q S+ +PL L +A P+P PR QSP + PP++ + +P K
Sbjct: 2416 QSQSSSQSPLTPRPLSAEAFC---PSPVTPR-FQSPDPYS---RPPSRPQSRDPFAPLHK 2468
Score = 35.0 bits (79), Expect = 0.35
Identities = 32/99 (32%), Positives = 39/99 (39%), Gaps = 19/99 (19%)
Query: 248 PTDQPP--------LGNCPARPL--PPTSDATSPTSRWAPRRPPPPPPVLPLQPCSP-AQ 296
P +PP + N R L PP + + P S AP PP L P P A+
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE 4943
Query: 297 PPVLPALAPAPACPLPTSPPV--PAPHVTPHAPGPPDHP 333
PPV P+P PL +SP P P P G P
Sbjct: 4944 PPV-----PSP-LPLASSPESARPKPRARPPEEGEDSRP 4976
Score = 33.9 bits (76), Expect = 0.77
Identities = 30/81 (37%), Positives = 34/81 (41%), Gaps = 8/81 (9%)
Query: 261 PLPPTSDA-TSPTSRWAPRRPPPPPPVLPLQPCSPAQP-PVLPALAP---APACPLPTSP 315
P PPT + T S R+ PPP P P SP P P P P P PL P
Sbjct: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPL-AEP 4944
Query: 316 PVPAPHVTPHAPGPPDHPNQP 336
PVP+P P A P +P
Sbjct: 4945 PVPSP--LPLASSPESARPKP 4963
Score = 30.8 bits (68), Expect = 6.5
Identities = 54/248 (21%), Positives = 90/248 (36%), Gaps = 15/248 (6%)
Query: 278 RRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQP- 336
R+P P P++P QP + A + LAP+ A + H A P +QP
Sbjct: 3321 RQPGLPQPLMPTQPPAHA---LQQRLAPSMAMVSNQGHMLSGQH-GGQAGLVPQQSSQPV 3376
Query: 337 ----PMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLP---AKKNLPTAPPRR 389
PM T C ++++ + L + A + AK + +
Sbjct: 3377 LSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIK 3436
Query: 390 RVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPEL 449
+V + S+ +PGM + Q+SL Q S GP + G E A DP
Sbjct: 3437 KVMAQGSI-GVAPGMNRQ--QVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPN 3493
Query: 450 PRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAG 509
P T Q + +++ L T ++ + + + + Q A +AG
Sbjct: 3494 PPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAG 3553
Query: 510 TQHPPAQA 517
+ P A A
Sbjct: 3554 REFPEADA 3561
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 78.6 bits (192), Expect = 3e-14
Identities = 125/460 (27%), Positives = 162/460 (35%), Gaps = 95/460 (20%)
Query: 154 LRLPQAILEASSFTDLETIANLGLGFWDSSLNPPQERGKPAEPPRDRAPGFPLVSSLRPT 213
L+ P + +SS T L + A G P RG P P P + +LRP
Sbjct: 234 LQRPASRSLSSSATPLSSPARSG----------PSARGTPRAPAHPSQPKPKGLQALRPP 283
Query: 214 A-----HDANCACEIELSVGNDRLWFVNPIFIEDCSSALPTDQPPLGNCPARPLPPTSDA 268
DA A S +P+ S+AL + PP LP T +
Sbjct: 284 QVTPPRKDAAPALGPLSS---------SPLATPSPSAALQSQAPPT-------LPATPHS 327
Query: 269 TSPTSRWA---PRRPPPP--PPVLPLQPCSPAQPP----------VLPA----LAPAPAC 309
+S T + A P PP P PP L P PA PP L A L P
Sbjct: 328 SSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 387
Query: 310 PLPTSPPVPAPHVT-PHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPL 368
PL T PP P + P PP P PP+ P A P A+ +P
Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPASPPL-------SPLATPSPQAPNALAVHLLQAPF 440
Query: 369 QQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRE 428
P+PP+ A + P +PP VS + Q+P L+ PP P +P
Sbjct: 441 SPPPSPPVQAPFSPPASPP---VSPSATPPSQAP------PSLAAPPLQVPPSPPASPPM 491
Query: 429 STEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCTQAM 488
S + A P + P L + AK PP PP Q + PA + +
Sbjct: 492 SPSATPPPQ--APPPLAAPPL-QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548
Query: 489 A-----LETPTPG------------PPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSL 531
+ L TP P PP SP QA + PP S S P +L
Sbjct: 549 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA-PRRPPTPGPDTSVSGPRLTLAL 607
Query: 532 A-------SLSDSLGVSVMATDQDSYSTSSTEEELEQFSS 564
A S S S +S S S +ST EEL + S
Sbjct: 608 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 647
Score = 73.2 bits (178), Expect = 1e-12
Identities = 93/326 (28%), Positives = 117/326 (35%), Gaps = 67/326 (20%)
Query: 248 PTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQ--PCSPAQPPVLPALAP 305
P PP A PP S SP++ P + PP PLQ P PA PP+ P+ P
Sbjct: 439 PFSPPPSPPVQAPFSPPASPPVSPSAT-PPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497
Query: 306 APACPLP-TSPPV----PAPHVTPHAPGPP---------DHPNQPPMMTCERLPCPTAGL 351
P P P +PP+ P P P PP P Q P LP
Sbjct: 498 PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 557
Query: 352 GPLREEAMKPGAASSPLQQVP-----APPLPAKKNLPTAPPRRRVS-ERVSLE------- 398
P P ++PL QVP +P L A + PT P VS R++L
Sbjct: 558 PP----PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613
Query: 399 --DQSPGMAAEGDQLSLPPQGTSDGPEDTPRE--STEQGQDTEVKASDPHSMPELPRTAK 454
+SP G L+ G S TP E + G + AS P P+ A
Sbjct: 614 PPSRSPSSTLSGPDLA----GHSSSATSTPEELRGYDSGPEGGAAASPP---PDAELAAC 666
Query: 455 QP------PVPPPRKKRISRQLASTLPAPLENAE-------LCT----QAMALETPTPGP 497
P P PP ++ + A P P A LCT + TP PG
Sbjct: 667 HPAAWSRGPAPP-----LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 721
Query: 498 PREGQSPASQAGTQHPPAQATAHSQS 523
G SP + G A A A S+S
Sbjct: 722 LDPGPSPGTSGGKAAAGAGAGASSRS 747
Score = 40.0 bits (92), Expect = 0.011
Identities = 66/281 (23%), Positives = 94/281 (33%), Gaps = 47/281 (16%)
Query: 302 ALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKP 361
A AP P P P P P VTP A G PL E A
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLG-------------AAGAVGRKPLAERAGGI 65
Query: 362 GAASSPLQQVPAPPL----PAKKNLPTAPPRRRVSERV-SLEDQSPGMAAEGDQLS---L 413
G A+ P A P + +N + PP ER ++ SPG + + S
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
Query: 414 PPQGTSDGPEDTPRESTEQGQDTEV-KASDPHSMPELPRTAKQPPVPPPRKKRISRQLAS 472
P G + E+ +G+ TE K S + + P P P R SR +
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
Query: 473 T--LPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGS 530
LP P +A P PP EG + + ++H + + ++ P
Sbjct: 186 EVGLPRPAPSAR------------PRPPTEGPRKSVSSASEHSTTEPSPAARRRP----- 228
Query: 531 LASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKKP 571
S G + S S+S+T S PS + P
Sbjct: 229 ------SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
Score = 39.7 bits (91), Expect = 0.014
Identities = 68/294 (23%), Positives = 99/294 (33%), Gaps = 49/294 (16%)
Query: 277 PRRPPPPPPVLP--LQPCSPA----QPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPP 330
P P PPPPV P L+ A + P+ +P S P P +
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
Query: 331 DHPNQPPMMTCERL-PCPTAGLGPLREE-----AMKPGAASSPLQQVPAPPLPAKKNLPT 384
P ER P GP+ +PG ++ A A+
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
Query: 385 APPR-------RRVSERVSLEDQSPGMA----AEGDQLSLPPQGTSDGPEDTPRESTEQG 433
AP R RR + + SP MA A G ++ LP P PR TE
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP----RPAPSARPRPPTEGP 205
Query: 434 QDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLAS-----------------TLPA 476
+ + AS+ + P ++P ++ SR L+S T A
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265
Query: 477 PLENAELCTQAM-ALETPTPGPPREGQSPA----SQAGTQHPPAQATAHSQSSP 525
P ++ + + AL P PPR+ +PA S + P A SQ+ P
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP 319
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 77.8 bits (190), Expect = 5e-14
Identities = 104/371 (28%), Positives = 132/371 (35%), Gaps = 72/371 (19%)
Query: 246 ALPTDQPPLGNCPARP---LPPTSDA--------TSPTSRWAPRRPPPP--PPVLPLQPC 292
A P+ P G RP PP DA +SP + +P PP P PP L P
Sbjct: 258 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS 317
Query: 293 SPAQPP----------VLPA----LAPAPACPLPTSPPVPAPHVT-PHAPGPPDHPNQPP 337
PA PP L A L P PL T PP P + P PP P PP
Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 377
Query: 338 MMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSL 397
+ P A P A+ +P P+PP+ A + P +PP VS +
Sbjct: 378 L-------SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP---VSPSATP 427
Query: 398 EDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPP 457
Q+P L+ PP P +P S + A P + P L + AK PP
Sbjct: 428 PSQAP------PSLAAPPLQVPPSPPASPPMSPSATPPPQ--APPPLAAPPL-QLAKPPP 478
Query: 458 VPPPRKKRISRQLASTLPAPLENAELCTQAMA-----LETPTPG------------PPRE 500
PP Q + PA + + + L TP P PP
Sbjct: 479 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538
Query: 501 GQSPASQAGTQHPPAQATAHSQSSPEFKGSLA-------SLSDSLGVSVMATDQDSYSTS 553
SP QA + PP S S P +LA S S S +S S S +
Sbjct: 539 PASPTLQA-PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597
Query: 554 STEEELEQFSS 564
ST EEL + S
Sbjct: 598 STPEELRGYDS 608
Score = 68.9 bits (167), Expect = 2e-11
Identities = 102/373 (27%), Positives = 128/373 (34%), Gaps = 53/373 (14%)
Query: 186 PPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSS 245
PPQ A PP P P L P A + A L+V + F P +
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA-LAVHLLQAPFSPPPSPPVQAP 412
Query: 246 ALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAP 305
P PP+ P +P + P PP PP+ P P PP L A
Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLAAPPLQ-VPPSPPASPPMSPSATPPPQAPPPLAAPPL 471
Query: 306 APACPLPTSPPVPAPHVTPHAPGPP-DHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAA 364
A P P +PP A P PP P Q P LP P P
Sbjct: 472 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP----PQAPPVL 527
Query: 365 SSPLQQVP-----APPLPAKKNLPTAPPRRRVS-ERVSL---------EDQSPGMAAEGD 409
++PL QVP +P L A + PT P VS R++L +SP G
Sbjct: 528 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 587
Query: 410 QLSLPPQGTSDGPEDTPRE--STEQGQDTEVKASDPHSMPELPRTAKQP------PVPPP 461
L+ G S TP E + G + AS P P+ A P P PP
Sbjct: 588 DLA----GHSSSATSTPEELRGYDSGPEGGAAASPP---PDAELAACHPAAWSRGPAPP- 639
Query: 462 RKKRISRQLASTLPAPLENAE-------LC----TQAMALETPTPGPPREGQSPASQAGT 510
++ + A P P A LC T+ TP PG G SP + G
Sbjct: 640 ----LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGK 695
Query: 511 QHPPAQATAHSQS 523
A A A S+S
Sbjct: 696 AAAGAGAGASSRS 708
Score = 48.1 bits (113), Expect = 4e-05
Identities = 69/293 (23%), Positives = 101/293 (34%), Gaps = 42/293 (14%)
Query: 277 PRRPPPPPPVLP--LQPCSPA----QPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPP 330
P P PPPPV P L+ A + P+ +P S P P T P
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASG 89
Query: 331 DHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPR-- 388
PP P + G +PG ++ A A+ AP R
Sbjct: 90 RGERAPPAKNTSPGPVSSPGRA---SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSA 146
Query: 389 -----RRVSERVSLEDQSPGMA----AEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVK 439
RR + + SP MA A G ++ LP P PR TE + +
Sbjct: 147 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP----RPAPSARPRPPTEGPRKSVSS 202
Query: 440 ASDPHSMPELPRTAKQPPVPPPRKKRISRQLAS-----------------TLPAPLENAE 482
AS+ + P ++P ++ SR L+S T AP ++
Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 262
Query: 483 LCTQAM-ALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASL 534
+ + AL P PPR+ +PA + P A + + SP SL +L
Sbjct: 263 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315
Score = 39.7 bits (91), Expect = 0.014
Identities = 68/279 (24%), Positives = 92/279 (32%), Gaps = 52/279 (18%)
Query: 302 ALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKP 361
A AP P P P P P VTP A G PL E A
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLG-------------AAGAVGRKPLAERAGGI 65
Query: 362 GAASSPLQQVPAPPL-----PAKKNLPTAPPRRRVSE-RVSLEDQSPGMAAEGDQLSLPP 415
G A+ P A P PA APP + S VS ++ G G P
Sbjct: 66 GGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG------P 119
Query: 416 QGTSDGPEDTPRESTEQGQDTEV-KASDPHSMPELPRTAKQPPVPPPRKKRISRQLAST- 473
G G + E+ +G+ TE K S + + P P P R SR +
Sbjct: 120 LG-QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 178
Query: 474 -LPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLA 532
LP P +A P PP EG + + ++H + + ++ P
Sbjct: 179 GLPRPAPSAR------------PRPPTEGPRKSVSSASEHSTTEPSPAARRRP------- 219
Query: 533 SLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKKP 571
S G + S S+S+T S PS + P
Sbjct: 220 ----SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 254
Score = 33.1 bits (74), Expect = 1.3
Identities = 38/160 (23%), Positives = 60/160 (37%), Gaps = 12/160 (7%)
Query: 424 DTPRESTEQGQDTEVKASDPHSM--PELPRTAKQPPVPPPRKKRISRQLASTLPAPL-EN 480
D R+ + G A+ + P P + + PP P R+ + PL E
Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
Query: 481 AELCTQAMALET-PTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLG 539
A A E+ P GP R + PAS G + PPA+ T+ S + S + LG
Sbjct: 62 AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 121
Query: 540 VSVMATDQDSYSTSSTEEELEQFSSPSVKKKPSMILGKAR 579
+ S EE + + + K+ ++ G R
Sbjct: 122 QKGLRI--------SAEETVARGKATEAPKRSALSAGARR 153
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 76.3 bits (186), Expect = 1e-13
Identities = 94/358 (26%), Positives = 132/358 (36%), Gaps = 60/358 (16%)
Query: 248 PTDQPPLGNCPARPLPPTSDATSPTSRWAPR-RPPPPPPVLPLQPCSPAQPPVLPALAPA 306
PT P + LP DA+ P ++ A R P LP SP++PP+
Sbjct: 261 PTQTPQTDHAK---LPLQRDASRPQTKQADIVRGESVKPSLP----SPSKPPIQQ----- 308
Query: 307 PACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASS 366
P P PP P PGP P QP +T + A +PG
Sbjct: 309 ---PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT--------------KPLAQQPGTVKP 351
Query: 367 PLQQVPAPPLPAKKNLPTAPPRRRV-SERVSLEDQSPGMAAEGDQLSLPPQ---GTSDGP 422
P+Q PA+ P PP ++ SE+ S E P A+ + P G + P
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 423 ED---TPRESTEQ-GQDTEVKASDPHSMP-ELPRTAKQPPVPPPRKKRISRQLAST---- 473
TP+ +Q G + KA P P + P K P K ++Q T
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Query: 474 -LPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLA 532
LP P A+ Q P P P + P+ Q G+ PP Q ++ SP+ GS
Sbjct: 472 QLPGP---AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528
Query: 533 SLSDSLGVSVMATDQDSYSTSSTEEELEQFS-------------SPSVKKKPSMILGK 577
S G + + Q S + S ++ + S SPS K+ PS L K
Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Score = 70.1 bits (170), Expect = 1e-11
Identities = 76/314 (24%), Positives = 110/314 (35%), Gaps = 51/314 (16%)
Query: 258 PARPLPPTSDATSPTSRWAPR-RPPPPPPVL---PLQPCSPAQPPVLPALAPAPACPLPT 313
PA+P S T P ++ +PP PP P QP PA+PP + P+ P
Sbjct: 328 PAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG 387
Query: 314 SPPVPAP----HVTPHAPGPPDHPNQ-----PPMMTCERLPCPTAGLGPLREEAMKPGAA 364
+ P PGP P Q P+ L P GP + +PG
Sbjct: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447
Query: 365 SSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPED 424
P QQ A++ PT PP Q PG A PPQ GP
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPP-----------SQLPGPAKP------PPQ--QPGPAK 488
Query: 425 TPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELC 484
P + + + P+ P AK P P K S+Q S P
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP--------- 539
Query: 485 TQAMALETPTPGPPREGQS--PASQAGT----QHPPAQATAHSQSSPEFKGSLASLSDSL 538
+ + P+P P QS P SQ G+ Q P +A S ++ L ++
Sbjct: 540 ----SAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595
Query: 539 GVSVMATDQDSYST 552
+ + ++ +++T
Sbjct: 596 ELLLHVPEKANFNT 609
Score = 57.0 bits (136), Expect = 9e-08
Identities = 93/363 (25%), Positives = 128/363 (35%), Gaps = 91/363 (25%)
Query: 244 SSALPTDQP-PLGNCPARPLPPTSDATSPTSRWAPRRPPP--PPPVLPLQPCSPA-QPPV 299
+SA+ P P P + P D + P++PPP P L P + A QPP
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE---PKKPPPLVKQPTLHGSPSAKAKQPPE 725
Query: 300 LPALA-PAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEA 358
+L+ PAP P P VP+ AP D P QP M+ PT L
Sbjct: 726 ADSLSKPAP----PKEPSVPSEQ--DKAPVADDKPKQPKMVK------PTTDLVSSSSAT 773
Query: 359 MKPGAASSPLQ----QVPAPPLPAKKNLPTA--PPRRRVSERVSLEDQS--PGMAAEGDQ 410
KP SS +Q + PPL P+ PP E+VS D P A++
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP---TGEKVSPFDSKAIPRPASDSKI 830
Query: 411 LSLP-PQGTSDGPEDT-PRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPP------- 461
+S P P S G + P + E+ + + K S +P+ + PP P P
Sbjct: 831 ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP 890
Query: 462 ----------RKKRISRQLASTLPAPLEN----------------AELCTQAMAL----- 490
+ +R S L S AP A + +QA L
Sbjct: 891 TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAG 950
Query: 491 ---------------ETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLS 535
+ P P P Q P G Q PPA A +S P K + A +
Sbjct: 951 QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTG-QAPPAPA----KSIPVKKETKAPAA 1005
Query: 536 DSL 538
+ L
Sbjct: 1006 EKL 1008
Score = 54.7 bits (130), Expect = 4e-07
Identities = 98/406 (24%), Positives = 140/406 (34%), Gaps = 53/406 (13%)
Query: 186 PPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSS 245
PPQ+ G PA+PP + PG S +P + G + P + S+
Sbjct: 480 PPQQPG-PAKPPPQQ-PG-----SAKPPSQQPGSTKPPPQQPGPAK-----PSPQQPGST 527
Query: 246 ALPTDQP----PLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLP 301
P+ QP P P+ P +T P S+ +P PP V P S QPP
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP----SAKQPP--S 581
Query: 302 ALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGP-------- 353
P CPL + + HV P+ N C+ C G P
Sbjct: 582 QGLPKTICPLCNTTEL-LLHV-------PEKANFNTCTECQTTVCSLCGFNPNPHLTEVK 633
Query: 354 --LREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGM-AAEGDQ 410
L A L VP+ P P K P + SP AA
Sbjct: 634 EWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
Query: 411 LSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPEL--PRTAKQPPVPPPRKKRISR 468
LS P+ P ++ T G + KA P L P K+P VP + K
Sbjct: 694 LSKAPEPKK--PPPLVKQPTLHGSPS-AKAKQPPEADSLSKPAPPKEPSVPSEQDK---A 747
Query: 469 QLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEF- 527
+A P + + T ++ + T P SQA + P T ++ S F
Sbjct: 748 PVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 528 -KGSLASLSDSLGVSVMATDQD--SYSTSSTEEELEQFSSPSVKKK 570
G S DS + A+D S+ S+E + ++ P KK+
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Score = 53.9 bits (128), Expect = 7e-07
Identities = 41/156 (26%), Positives = 60/156 (38%), Gaps = 15/156 (9%)
Query: 241 EDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVL 300
E +S LP+ P + + PA+P P ++ S P PPPPPP P P P PP+
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP-PPPPPPPPPPPLP 2428
Query: 301 PALAPAP----------ACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAG 350
P +P P A P+ T+ P+ T P C P P
Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV-- 2486
Query: 351 LGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAP 386
P + ++ G + + PP+ K +P P
Sbjct: 2487 --PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520
Score = 51.6 bits (122), Expect = 4e-06
Identities = 53/219 (24%), Positives = 78/219 (35%), Gaps = 18/219 (8%)
Query: 355 REEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSP-GMAAEGDQLSL 413
+E+ G PLQQ P P+P K+ P P ++ S+ Q P + ++
Sbjct: 198 KEQGKPEGIIKPPLQQQPPKPIP-KQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK 256
Query: 414 PPQGTSDGPE----------DTPRESTEQ-----GQDTEVKASDPHSMPELPRTAKQPPV 458
P QG + P+ D R T+Q G+ + P P T +PP
Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPA 316
Query: 459 PPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQAT 518
P ++ A P + Q P PP + PA G PPAQ T
Sbjct: 317 QQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQT 376
Query: 519 AHSQSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEE 557
+ S E G A L+ GV Q + T++
Sbjct: 377 GSEKPSSEQPGPKA-LAQPPGVGKTPAQQPGPAKPPTQQ 414
Score = 39.7 bits (91), Expect = 0.014
Identities = 65/273 (23%), Positives = 87/273 (31%), Gaps = 49/273 (17%)
Query: 244 SSALPTDQPPLGNCPARP---LPPTSDATSP-TSRWAPR---------RPPPPPPVLPLQ 290
S A PPL A+P PPT + SP S+ PR P P +
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 291 PCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAG 350
P Q P A P P + P+P TP PGP PTAG
Sbjct: 845 QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTP--PGPR----------------PTAG 886
Query: 351 -LGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSE----RVSLEDQSPGMA 405
P +++ KP S A K+ PT P + S+ Q+ +
Sbjct: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI 946
Query: 406 AEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPP---PR 462
+ Q P + GP +++ Q P S T + PP P P
Sbjct: 947 STAGQ---PGPHSQSGPGAPMKQAPAPSQ-------PPTSQGPPKSTGQAPPAPAKSIPV 996
Query: 463 KKRISRQLASTLPAPLENAELCTQAMALETPTP 495
KK A L E A + + P P
Sbjct: 997 KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Score = 35.0 bits (79), Expect = 0.35
Identities = 53/203 (26%), Positives = 75/203 (36%), Gaps = 22/203 (10%)
Query: 186 PPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSS 245
PP P PP P P +S +PT +L+V + + P+F D +
Sbjct: 2409 PPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKK-----KLTVASP-VTTATPLF--DAVT 2460
Query: 246 ALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQP-PVLPALA 304
L T N LP T T+ AP PP P +P +P P P +A
Sbjct: 2461 TLETTAVLRSN----GLPVTRICTT-----APPPVPPKPSSIPSGLVFTHRPEPSKPPIA 2511
Query: 305 PAPACP-LPTSPPVPAP-HVTPHAPGPPDHPNQPPMMTCE-RLPCPTAGLGPLREEAMKP 361
P P P LPT+ P H P + + + +LP PT+ L P P
Sbjct: 2512 PKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSP-HSNKSSP 2570
Query: 362 GAASSPLQQVPAPPLPAKKNLPT 384
+ S + LP++ PT
Sbjct: 2571 RFSKSLTETYVVITLPSEPGTPT 2593
Score = 34.3 bits (77), Expect = 0.59
Identities = 44/184 (23%), Positives = 64/184 (34%), Gaps = 39/184 (21%)
Query: 245 SALPTDQPPLGNCPARPLP-PTSDATSPTSRWAPRRP----------------PPPPPVL 287
S P +P P P P PT+ T PT + +P+ P P
Sbjct: 863 SPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTT 922
Query: 288 PLQPC------------SPAQPPVLPALAPAPACPLPTSPPV---PAPHVTPHAPGPPDH 332
P + S A + A P P P+ PAP P + GPP
Sbjct: 923 PQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS 982
Query: 333 PNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPL-----QQVPAPPLPAKKNLPTAPP 387
Q P + +P P E+ ++P A +P + PP+ K+L TA P
Sbjct: 983 TGQAPPAPAKSIPVKKETKAPAAEK-LEPKAEQAPTVKRTETEKKPPPIKDSKSL-TAEP 1040
Query: 388 RRRV 391
++ V
Sbjct: 1041 QKAV 1044
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 76.3 bits (186), Expect = 1e-13
Identities = 94/358 (26%), Positives = 132/358 (36%), Gaps = 60/358 (16%)
Query: 248 PTDQPPLGNCPARPLPPTSDATSPTSRWAPR-RPPPPPPVLPLQPCSPAQPPVLPALAPA 306
PT P + LP DA+ P ++ A R P LP SP++PP+
Sbjct: 261 PTQTPQTDHAK---LPLQRDASRPQTKQADIVRGESVKPSLP----SPSKPPIQQ----- 308
Query: 307 PACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASS 366
P P PP P PGP P QP +T + A +PG
Sbjct: 309 ---PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT--------------KPLAQQPGTVKP 351
Query: 367 PLQQVPAPPLPAKKNLPTAPPRRRV-SERVSLEDQSPGMAAEGDQLSLPPQ---GTSDGP 422
P+Q PA+ P PP ++ SE+ S E P A+ + P G + P
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 423 ED---TPRESTEQ-GQDTEVKASDPHSMP-ELPRTAKQPPVPPPRKKRISRQLAST---- 473
TP+ +Q G + KA P P + P K P K ++Q T
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Query: 474 -LPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLA 532
LP P A+ Q P P P + P+ Q G+ PP Q ++ SP+ GS
Sbjct: 472 QLPGP---AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528
Query: 533 SLSDSLGVSVMATDQDSYSTSSTEEELEQFS-------------SPSVKKKPSMILGK 577
S G + + Q S + S ++ + S SPS K+ PS L K
Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Score = 70.1 bits (170), Expect = 1e-11
Identities = 76/314 (24%), Positives = 110/314 (35%), Gaps = 51/314 (16%)
Query: 258 PARPLPPTSDATSPTSRWAPR-RPPPPPPVL---PLQPCSPAQPPVLPALAPAPACPLPT 313
PA+P S T P ++ +PP PP P QP PA+PP + P+ P
Sbjct: 328 PAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG 387
Query: 314 SPPVPAP----HVTPHAPGPPDHPNQ-----PPMMTCERLPCPTAGLGPLREEAMKPGAA 364
+ P PGP P Q P+ L P GP + +PG
Sbjct: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447
Query: 365 SSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPED 424
P QQ A++ PT PP Q PG A PPQ GP
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPP-----------SQLPGPAKP------PPQ--QPGPAK 488
Query: 425 TPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELC 484
P + + + P+ P AK P P K S+Q S P
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP--------- 539
Query: 485 TQAMALETPTPGPPREGQS--PASQAGT----QHPPAQATAHSQSSPEFKGSLASLSDSL 538
+ + P+P P QS P SQ G+ Q P +A S ++ L ++
Sbjct: 540 ----SAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595
Query: 539 GVSVMATDQDSYST 552
+ + ++ +++T
Sbjct: 596 ELLLHVPEKANFNT 609
Score = 57.0 bits (136), Expect = 9e-08
Identities = 93/363 (25%), Positives = 128/363 (35%), Gaps = 91/363 (25%)
Query: 244 SSALPTDQP-PLGNCPARPLPPTSDATSPTSRWAPRRPPP--PPPVLPLQPCSPA-QPPV 299
+SA+ P P P + P D + P++PPP P L P + A QPP
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE---PKKPPPLVKQPTLHGSPSAKAKQPPE 725
Query: 300 LPALA-PAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEA 358
+L+ PAP P P VP+ AP D P QP M+ PT L
Sbjct: 726 ADSLSKPAP----PKEPSVPSEQ--DKAPVADDKPKQPKMVK------PTTDLVSSSSAT 773
Query: 359 MKPGAASSPLQ----QVPAPPLPAKKNLPTA--PPRRRVSERVSLEDQS--PGMAAEGDQ 410
KP SS +Q + PPL P+ PP E+VS D P A++
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP---TGEKVSPFDSKAIPRPASDSKI 830
Query: 411 LSLP-PQGTSDGPEDT-PRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPP------- 461
+S P P S G + P + E+ + + K S +P+ + PP P P
Sbjct: 831 ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP 890
Query: 462 ----------RKKRISRQLASTLPAPLEN----------------AELCTQAMAL----- 490
+ +R S L S AP A + +QA L
Sbjct: 891 TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAG 950
Query: 491 ---------------ETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLS 535
+ P P P Q P G Q PPA A +S P K + A +
Sbjct: 951 QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTG-QAPPAPA----KSIPVKKETKAPAA 1005
Query: 536 DSL 538
+ L
Sbjct: 1006 EKL 1008
Score = 54.7 bits (130), Expect = 4e-07
Identities = 98/406 (24%), Positives = 140/406 (34%), Gaps = 53/406 (13%)
Query: 186 PPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSS 245
PPQ+ G PA+PP + PG S +P + G + P + S+
Sbjct: 480 PPQQPG-PAKPPPQQ-PG-----SAKPPSQQPGSTKPPPQQPGPAK-----PSPQQPGST 527
Query: 246 ALPTDQP----PLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLP 301
P+ QP P P+ P +T P S+ +P PP V P S QPP
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP----SAKQPP--S 581
Query: 302 ALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGP-------- 353
P CPL + + HV P+ N C+ C G P
Sbjct: 582 QGLPKTICPLCNTTEL-LLHV-------PEKANFNTCTECQTTVCSLCGFNPNPHLTEVK 633
Query: 354 --LREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGM-AAEGDQ 410
L A L VP+ P P K P + SP AA
Sbjct: 634 EWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
Query: 411 LSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPEL--PRTAKQPPVPPPRKKRISR 468
LS P+ P ++ T G + KA P L P K+P VP + K
Sbjct: 694 LSKAPEPKK--PPPLVKQPTLHGSPS-AKAKQPPEADSLSKPAPPKEPSVPSEQDK---A 747
Query: 469 QLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEF- 527
+A P + + T ++ + T P SQA + P T ++ S F
Sbjct: 748 PVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 528 -KGSLASLSDSLGVSVMATDQD--SYSTSSTEEELEQFSSPSVKKK 570
G S DS + A+D S+ S+E + ++ P KK+
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Score = 53.9 bits (128), Expect = 7e-07
Identities = 41/156 (26%), Positives = 60/156 (38%), Gaps = 15/156 (9%)
Query: 241 EDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVL 300
E +S LP+ P + + PA+P P ++ S P PPPPPP P P P PP+
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP-PPPPPPPPPPPLP 2428
Query: 301 PALAPAP----------ACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAG 350
P +P P A P+ T+ P+ T P C P P
Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV-- 2486
Query: 351 LGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAP 386
P + ++ G + + PP+ K +P P
Sbjct: 2487 --PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520
Score = 51.6 bits (122), Expect = 4e-06
Identities = 53/219 (24%), Positives = 78/219 (35%), Gaps = 18/219 (8%)
Query: 355 REEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSP-GMAAEGDQLSL 413
+E+ G PLQQ P P+P K+ P P ++ S+ Q P + ++
Sbjct: 198 KEQGKPEGIIKPPLQQQPPKPIP-KQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK 256
Query: 414 PPQGTSDGPE----------DTPRESTEQ-----GQDTEVKASDPHSMPELPRTAKQPPV 458
P QG + P+ D R T+Q G+ + P P T +PP
Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPA 316
Query: 459 PPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQAT 518
P ++ A P + Q P PP + PA G PPAQ T
Sbjct: 317 QQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQT 376
Query: 519 AHSQSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEE 557
+ S E G A L+ GV Q + T++
Sbjct: 377 GSEKPSSEQPGPKA-LAQPPGVGKTPAQQPGPAKPPTQQ 414
Score = 39.7 bits (91), Expect = 0.014
Identities = 65/273 (23%), Positives = 87/273 (31%), Gaps = 49/273 (17%)
Query: 244 SSALPTDQPPLGNCPARP---LPPTSDATSP-TSRWAPR---------RPPPPPPVLPLQ 290
S A PPL A+P PPT + SP S+ PR P P +
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 291 PCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAG 350
P Q P A P P + P+P TP PGP PTAG
Sbjct: 845 QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTP--PGPR----------------PTAG 886
Query: 351 -LGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSE----RVSLEDQSPGMA 405
P +++ KP S A K+ PT P + S+ Q+ +
Sbjct: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI 946
Query: 406 AEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPP---PR 462
+ Q P + GP +++ Q P S T + PP P P
Sbjct: 947 STAGQ---PGPHSQSGPGAPMKQAPAPSQ-------PPTSQGPPKSTGQAPPAPAKSIPV 996
Query: 463 KKRISRQLASTLPAPLENAELCTQAMALETPTP 495
KK A L E A + + P P
Sbjct: 997 KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Score = 35.0 bits (79), Expect = 0.35
Identities = 53/203 (26%), Positives = 75/203 (36%), Gaps = 22/203 (10%)
Query: 186 PPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSS 245
PP P PP P P +S +PT +L+V + + P+F D +
Sbjct: 2409 PPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKK-----KLTVASP-VTTATPLF--DAVT 2460
Query: 246 ALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQP-PVLPALA 304
L T N LP T T+ AP PP P +P +P P P +A
Sbjct: 2461 TLETTAVLRSN----GLPVTRICTT-----APPPVPPKPSSIPSGLVFTHRPEPSKPPIA 2511
Query: 305 PAPACP-LPTSPPVPAP-HVTPHAPGPPDHPNQPPMMTCE-RLPCPTAGLGPLREEAMKP 361
P P P LPT+ P H P + + + +LP PT+ L P P
Sbjct: 2512 PKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSP-HSNKSSP 2570
Query: 362 GAASSPLQQVPAPPLPAKKNLPT 384
+ S + LP++ PT
Sbjct: 2571 RFSKSLTETYVVITLPSEPGTPT 2593
Score = 34.3 bits (77), Expect = 0.59
Identities = 44/184 (23%), Positives = 64/184 (34%), Gaps = 39/184 (21%)
Query: 245 SALPTDQPPLGNCPARPLP-PTSDATSPTSRWAPRRP----------------PPPPPVL 287
S P +P P P P PT+ T PT + +P+ P P
Sbjct: 863 SPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTT 922
Query: 288 PLQPC------------SPAQPPVLPALAPAPACPLPTSPPV---PAPHVTPHAPGPPDH 332
P + S A + A P P P+ PAP P + GPP
Sbjct: 923 PQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS 982
Query: 333 PNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPL-----QQVPAPPLPAKKNLPTAPP 387
Q P + +P P E+ ++P A +P + PP+ K+L TA P
Sbjct: 983 TGQAPPAPAKSIPVKKETKAPAAEK-LEPKAEQAPTVKRTETEKKPPPIKDSKSL-TAEP 1040
Query: 388 RRRV 391
++ V
Sbjct: 1041 QKAV 1044
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 75.5 bits (184), Expect = 2e-13
Identities = 99/377 (26%), Positives = 137/377 (36%), Gaps = 61/377 (16%)
Query: 186 PPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSS 245
PP +G PA PP AP P + P + A N + V P
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAAT---PPSLKGGLATPPHKGAPNPAV--VTP----PSPK 1298
Query: 246 ALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLP--LQPCSPAQPPVLPAL 303
P PP G P PP AT P+ + +P PPP P + P SP P LPA
Sbjct: 1299 GGPATSPPKG----APTPPA--ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPAT 1352
Query: 304 APA----PACPL----PTSPPV------------PAPHVTPHAPGPPDHPNQPPMMTCER 343
P+ P P PT P P+P P P P P P ++
Sbjct: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
Query: 344 LPCPTAGLGPLREEAMKPG------AASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSL 397
P + RE A P A +P+ AP A K P P + ++
Sbjct: 1413 KKAPATPV--TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470
Query: 398 EDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDT--EVKASDPHSMPELPRTAKQ 455
SP Q++ TS P+ P G T V S P +P P + +
Sbjct: 1471 TPPSPKEPPAPKQVA-----TSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
Query: 456 PPVPPPRKKRISRQLASTLPAPLENAELCTQAMALETP--TPGPPREGQSPASQAGTQ-- 511
P P +S++ +TL AP E L AM + +P TP P ++PA+ + +
Sbjct: 1526 PIA--PTATLLSKKTPATL-APKE--ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS 1580
Query: 512 HPPAQATAHSQSSPEFK 528
PPA + + +P K
Sbjct: 1581 SPPAVTPSTYKGAPSPK 1597
Score = 74.7 bits (182), Expect = 4e-13
Identities = 92/325 (28%), Positives = 112/325 (34%), Gaps = 54/325 (16%)
Query: 247 LPTDQPPLGNCPARPLPPTSDATS-------PTSRWAPRRP---PPPPPVLPLQPCSPAQ 296
+P P G P PP + S P+ +WAP P PP P P P SP
Sbjct: 930 IPASPSPKG----APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP-SPKG 984
Query: 297 PPVLPALAP-----APACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGL 351
P PA P PA P P P P P VTP P P P P P
Sbjct: 985 APTPPAATPPSPKGGPATPSPKGAPTP-PAVTP--PSPKGSPAATPFPKGASTPPAATPP 1041
Query: 352 GPLREEAMKP---GAASSPLQQVPA----PPLPAKKNLPTAPPRRRVSERVSLEDQSPGM 404
P A P GA ++P +P+ P P+ K PT P S + SP
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101
Query: 405 AAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPEL--------PRT-AKQ 455
A +PP T P+ +G T A+ P L P T A
Sbjct: 1102 A------PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1155
Query: 456 PPVP-----PPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGT 510
PP P P K A+T P+P + A TP PP SP T
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP----SPKGGLAT 1211
Query: 511 QHPPAQATAHSQSSPEFKGSLASLS 535
P T + + P KG LA+ S
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPS 1236
Score = 72.0 bits (175), Expect = 3e-12
Identities = 95/362 (26%), Positives = 123/362 (33%), Gaps = 42/362 (11%)
Query: 186 PPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSS 245
PP +G PA P AP P + P A + + P
Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATPPSPKGGPA---------TPSPKGAPTPPAATPPSPK 997
Query: 246 ALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQP-CSPAQPPVLPALA 304
P P G + P S SP + P+ PP P P SPA P+
Sbjct: 998 GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP 1057
Query: 305 PAPACPLPTSPPVPA-PHV----TPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAM 359
PA LP+ PA P + TP A PP P + + P P A P +
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP----SP 1113
Query: 360 KPGAASSPLQQVPAPPL---PAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQ 416
K G A+ P + P P P+ K PP + + SP +G + PP+
Sbjct: 1114 KGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP----KGGLATPPPK 1169
Query: 417 GTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVP-----PPRKKRISRQLA 471
G P TP S + G T P P P A PP P P K A
Sbjct: 1170 GAPTTPAATP-PSPKGGLAT----PSPKGAPTTP--AATPPSPKGGLATPSPKGAPTTPA 1222
Query: 472 STLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSL 531
+T P+P + A TP PP SP T P T + + P KG L
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPP----SPKGGPATPPPKGAPTPPAATPPSLKGGL 1278
Query: 532 AS 533
A+
Sbjct: 1279 AT 1280
Score = 68.6 bits (166), Expect = 3e-11
Identities = 85/310 (27%), Positives = 107/310 (34%), Gaps = 33/310 (10%)
Query: 245 SALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPP-PVLPLQPCSPAQPPVLPAL 303
SA+ P P + P S P + P P P P L + SP + PA
Sbjct: 868 SAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAP 927
Query: 304 APAPACPLPTSPPVPAPHVTPHAP--GP-PDHPNQPPMMTCERLPCPTAG-LGPLREEAM 359
PA P P P P P TP +P GP P P P P G P + A
Sbjct: 928 KGIPASPSPKGAPTP-PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986
Query: 360 KPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTS 419
P AA+ P + P P+ K PT P S + SP S PP T
Sbjct: 987 TPPAATPPSPK-GGPATPSPKGAPTPPAVTPPSPK-----GSPAATPFPKGASTPPAATP 1040
Query: 420 DGPEDTPRES-TEQGQDTEVKAS--DPHSMPELPRTAKQPPVPP-------------PRK 463
P+ +P + +G T A+ P P P + K P PP P
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP-SLKGAPTPPAATPPSPKGGPATPSP 1099
Query: 464 KRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQS 523
K A+T P+P A TP PP SP T P T + +
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP----SPKGGLATPPPKGAPTTPAAT 1155
Query: 524 SPEFKGSLAS 533
P KG LA+
Sbjct: 1156 PPSPKGGLAT 1165
Score = 66.6 bits (161), Expect = 1e-10
Identities = 94/392 (23%), Positives = 122/392 (31%), Gaps = 61/392 (15%)
Query: 186 PPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSS 245
PP +G A PP AP P + P L+ + P
Sbjct: 1110 PPSPKGGLATPPHKGAPTTPAATPPSPKGG---------LATPPPKGAPTTPAATPPSPK 1160
Query: 246 ALPTDQPPLG---NCPARPLPPTSDATSPTSRWAPRRPP--PPPPVLPLQPCSPAQPPVL 300
PP G A P P +P+ + AP P PP P L SP P
Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220
Query: 301 PALAP--------------APACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPC 346
PA P AP P T P TP G P P P L
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280
Query: 347 PTAGLGP----LREEAMKPGAASSPLQQVPAPPL---PAKKNLPTAPPRRRVSERVSLED 399
P P + + K G A+SP + P PP P+ K P PP + ++
Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340
Query: 400 QSP----------------GMAAEGDQLSLPPQGT---SDGPEDTPRESTEQGQDTEVKA 440
SP + PP T GP TP S ++G
Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP-PSPKRGPAIPSPK 1399
Query: 441 SDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGP--P 498
DP S +P + K+ P P ++ + L P +A A P GP P
Sbjct: 1400 GDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP 1459
Query: 499 REGQSPASQAGT----QHPPAQATAHSQSSPE 526
P A T + PPA + SSP+
Sbjct: 1460 SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491
Score = 60.5 bits (145), Expect = 8e-09
Identities = 103/405 (25%), Positives = 139/405 (34%), Gaps = 74/405 (18%)
Query: 187 PQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCA-----CEIELSVGNDRLWFVNPI-FI 240
P+ P+ PP PG V + T+ A A C E S + + ++
Sbjct: 731 PKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYL 790
Query: 241 EDCSSAL------PTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSP 294
D S L T +PP A P P + +SP S P LP S
Sbjct: 791 ADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVS-------PVEASFLPENSLSF 843
Query: 295 AQPPVLPALAPAPACPLPTSPPVPAPHVTPHAP-GPPDHPNQPPMMTCERLPCPTAG-LG 352
PA +P P P P P+ VTP +P G P + P + LP P G
Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPSA-VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT 902
Query: 353 PLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSP--GMAAEGDQ 410
P ++A SS ++ A P P K +P +P + + SP G A +
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAP--KGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960
Query: 411 LS-LPPQGTSDGPEDTPRESTEQGQDTEVKASDPH----SMPELPRTAKQPP-VPPPRKK 464
+ PP T P+ P + +G T A+ P P+ A PP V PP K
Sbjct: 961 WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020
Query: 465 RISRQL-----ASTLPA-------------PLENAELCTQAMALETPTPGP--------- 497
AST PA PL T A L +P GP
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080
Query: 498 ---------PREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLAS 533
P+ G + S G PPA + P KG LA+
Sbjct: 1081 TPPAATPPSPKGGPATPSPKGAPMPPA------ATPPSPKGGLAT 1119
Score = 59.7 bits (143), Expect = 1e-08
Identities = 86/376 (22%), Positives = 139/376 (36%), Gaps = 51/376 (13%)
Query: 190 RGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVN-PIFIEDCSSALP 248
+G PA P P P V+ P+ + ++ S + P+ + +P
Sbjct: 1453 KGGPATPSSKGDPTLPAVTP--PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP 1510
Query: 249 TDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLP--LQPCSPAQPPVLPALAPA 306
+ + P+ P + + S+ P P ++P + SP + P +P A
Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570
Query: 307 PACPLP---TSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGA 363
PA P +SPP P AP P + L P A P +EA P A
Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSP------------KELLIPPAVTSPSPKEAPTPPA 1618
Query: 364 ASSPLQQVPAPPLPAKKNLPTAPPRRRVSER--------------VSLEDQSPGMAAEGD 409
+ P + P PA K PT+PP S + ++ S G+ A+
Sbjct: 1619 VTPPSPE-KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKG 1677
Query: 410 QLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPV-PPPRKKRISR 468
+L + PE TP + + + K S +A PP+ P P K S+
Sbjct: 1678 PTALKEVLVAPAPESTPIITAPTRKGPQTKKS----------SATSPPICPDPSAKNGSK 1727
Query: 469 -QLASTLPAPLENAELCTQAMALETPTPGPPREGQS-PASQAGTQHPPAQATAHSQSSPE 526
L++ PAPL + + A P+ + P S+A T P A A + P+
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST---PLTAAAFEKVLPK 1784
Query: 527 FKGSLASLSDSLGVSV 542
+ + S + S VS+
Sbjct: 1785 PESASVSAAPSPPVSL 1800
Score = 49.7 bits (117), Expect = 1e-05
Identities = 66/274 (24%), Positives = 104/274 (37%), Gaps = 57/274 (20%)
Query: 262 LPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPH 321
+PP + S P+ P PP V P P+ PA P P P +P
Sbjct: 1601 IPPAVTSPS------PKEAPTPPAVTP------------PSPEKGPATPAPKGTPT-SPP 1641
Query: 322 VTPHAPGPPDHPNQPPMMTCE---RLPCPTAGL----GP--LREEAMKPGAASSPLQQVP 372
VTP + D P P +TC+ +P + GL GP L+E + P S+P+ P
Sbjct: 1642 VTPSS--LKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP 1699
Query: 373 APPLP-AKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTE 431
P KK+ T+PP D S ++G ++ P +D+ + T
Sbjct: 1700 TRKGPQTKKSSATSPP--------ICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK--TA 1749
Query: 432 QGQDTEVKASDPHSMPE------LPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCT 485
+G+D P + PE L A + +P P +S + + PL + + T
Sbjct: 1750 KGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPT 1809
Query: 486 QAMALETPTPGPPREGQSPASQAGTQHPPAQATA 519
PP++ P+S P++ A
Sbjct: 1810 L----------PPKQQFLPSSPGLVLESPSKPLA 1833
Score = 43.5 bits (101), Expect = 0.001
Identities = 80/360 (22%), Positives = 122/360 (33%), Gaps = 41/360 (11%)
Query: 246 ALPTDQPPLGNCPARPLPPTSDA--TSPTSRWAPRRPPPPPPVLPLQPCSPAQPPV-LPA 302
A+ + P P PP+ + +P + P PP P L P SPA + A
Sbjct: 1604 AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGA 1663
Query: 303 LAPAPACPLPTSPPVPAPHVTPHAPGPPDHP-NQPPMMTCERLPCPTAGLGPLREEAMKP 361
P + LP A AP P P P + +A P+ +
Sbjct: 1664 TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK 1723
Query: 362 GAASSPLQQV-PAPPLPAKKNL---------------PTAPPRRRVSERVSLEDQSPGMA 405
+ PL V PAP LP +K+ P APP + S +P A
Sbjct: 1724 NGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAS--------TPLTA 1775
Query: 406 AEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHS--MPELPRTAKQPPVPPPRK 463
A +++ P+ S +P S + V P +P P + P P
Sbjct: 1776 AAFEKVLPKPESASVSAAPSPPVSLPLA-PSPVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834
Query: 464 KRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQS 523
L P P+ + Q++ + PT P+ P + P + S +
Sbjct: 1835 ADEDELLPLIPPEPISGG-VPFQSVLVNMPT---PKSAGIPVPTPSAKQPVTKNNKGSGT 1890
Query: 524 SPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKKPSMILGKARHRLS 583
+ S+ L + S AT Q + ++ E + E P K K S KAR +S
Sbjct: 1891 ESDSDESVPELEEQ--DSTQATTQQAQLAAAAEIDEE----PVSKAKQSRSEKKARKAMS 1944
Score = 42.7 bits (99), Expect = 0.002
Identities = 76/301 (25%), Positives = 107/301 (35%), Gaps = 51/301 (16%)
Query: 264 PTSDATSPTSRWAPRRPPPPPPVLPL-QPC------------SPAQPPVLPALAPAP--- 307
P S A S T+ P PPP P Q C SP+ P P P
Sbjct: 27 PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS 86
Query: 308 ---ACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAA 364
A PL T+P AP P+ GPP P + + PT P ++
Sbjct: 87 SGTALPLGTAP--EAPTFLPNLIGPPISP--AALALASPMIAPTLKGTP---------SS 133
Query: 365 SSPLQQVPAPPLPAKK------NLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSL--PPQ 416
S+PL V P +K NL T+PP V+E S+ S +A + +L P
Sbjct: 134 SAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPS 193
Query: 417 GTSDGPEDTPRE----STEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLAS 472
P+ TP ST AS + LP+T + + ++S
Sbjct: 194 EVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISS 253
Query: 473 TLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLA 532
L +P L + P P S ++Q+ +Q TA + P+F SL
Sbjct: 254 VLISPQNPGSLSLKG-------PVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLG 306
Query: 533 S 533
S
Sbjct: 307 S 307
Score = 35.0 bits (79), Expect = 0.35
Identities = 98/414 (23%), Positives = 133/414 (32%), Gaps = 104/414 (25%)
Query: 206 LVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSSALPTD--------QPPLGNC 257
L SS T H A SVG L NP I +A PT PP+ +
Sbjct: 415 LKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTI----AAAPTTTFEVATCVSPPMSSG 470
Query: 258 PARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPV 317
P + PTS P L + P +P + P+ A +P SPP+
Sbjct: 471 PISNIEPTS-----------------PAALVMAPVAPKE----PSTQVATTLRIPVSPPL 509
Query: 318 PAPHVTPHAPG------PPDHPNQPPMMTCERLPCPTAGLG----------PLREEAMKP 361
P P + P P Q + E P A G PL + A K
Sbjct: 510 PDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKN 569
Query: 362 GAASSPLQQVPAPPLP-----AKKNL------------PTAPPRRRVSERVSLEDQSPGM 404
+ P PL AKK+L T+P S V D G
Sbjct: 570 SPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGP 629
Query: 405 AAEGDQLSLP---------PQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQ 455
+ G L P ++D P +T +G T + P + K
Sbjct: 630 DSAGPLLKSSLITPTVAAFPLESADPAGVAP--TTAKGTSTYTTTASPFLEGTVSLAPKN 687
Query: 456 PPVPPPRKKRI-----SRQLASTLPAPLEN-AELCTQAMALE----TPTPGPPREGQSPA 505
PV + + + P+P A L T +A E P+P P G P
Sbjct: 688 HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPG 747
Query: 506 SQA--GTQHPPAQATAHS------------QSSPEFKGSLASLSDS---LGVSV 542
++ G H A A S ++ KG+L L+DS LGVSV
Sbjct: 748 TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSV 801
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 75.1 bits (183), Expect = 3e-13
Identities = 79/301 (26%), Positives = 105/301 (34%), Gaps = 25/301 (8%)
Query: 246 ALPTDQPPLGNCPARPLPPTSDATSPTS-RWAPRRPPPPPPVLPLQ-PCSPAQPPVLPAL 303
AL T + P P P T +PT+ + AP P P P P +P +P
Sbjct: 209 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 268
Query: 304 APAPACP---LPTSPPVPAPHVTPHAPGPPDHP----NQPPMMTCERLPCPTAGLGPLRE 356
PAP P PT+ PAP T AP P P + P T + P PT P
Sbjct: 269 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 328
Query: 357 EAMKPG-AASSPLQQVPAPPLPA--KKNLPT-----APPRRRVSERVSLEDQSPGMAAEG 408
+P P P P P KK PT AP + + ++ SP E
Sbjct: 329 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 388
Query: 409 DQLSLPPQGTSDGPEDT--PRESTEQGQDTEVKASDPHSMPE-LPRTAKQPPVPPPRKKR 465
P T P T P +T + T K P + E P T K+P P+K
Sbjct: 389 -----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 443
Query: 466 ISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSP 525
+ P E A T+ A TP P + A + P + ++P
Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 503
Query: 526 E 526
E
Sbjct: 504 E 504
Score = 73.2 bits (178), Expect = 1e-12
Identities = 75/293 (25%), Positives = 104/293 (35%), Gaps = 20/293 (6%)
Query: 245 SALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALA 304
SA T + P P +P P T +PT+ P+ P P P P P A
Sbjct: 293 SAPTTPKEPAPTTPKKPAPTTPKEPAPTT---PKEPTPTTPKEPAPTTKEPAPTTPKEPA 349
Query: 305 P-APACPLPTSPPVPAPHVTPHAPGP-------PDHPNQPPMMTCERLPCPTAGLGP--L 354
P AP P PT+P PAP TP P P P P +P T + P T P
Sbjct: 350 PTAPKKPAPTTPKEPAP-TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408
Query: 355 REEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLP 414
+ P S + PAP P K+ PT P + + +P A
Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 467
Query: 415 PQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVP-PPRKKRISRQLAST 473
P + TP+E+ T K P + +L T + P P P + + T
Sbjct: 468 PTTPKEPAPTTPKETA----PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523
Query: 474 LPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPE 526
P E A +A A TP P + PA + P + ++P+
Sbjct: 524 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 576
Score = 70.9 bits (172), Expect = 6e-12
Identities = 77/329 (23%), Positives = 119/329 (36%), Gaps = 22/329 (6%)
Query: 258 PARPLPPTSDATSPTS--RWAPRRPPPPPPVLPLQPC--SPAQPPVLPALAPAPACPLPT 313
P P P T + +PT+ AP P P P P +P +P +P AP P T
Sbjct: 519 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 578
Query: 314 SPPV---PAPHVTPHAPGP----PDHPNQPPMMTCERLPCPTA--GLGPLREEAMKPGAA 364
+P PAP TP P P P +P TC++ P PT G P + P
Sbjct: 579 APTTLKEPAP-TTPKKPAPKELAPTTTKEPTSTTCDK-PAPTTPKGTAPTTPKEPAPTTP 636
Query: 365 SSPLQQVP--APPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGP 422
P P P K+ PT P + E + P P+ T+
Sbjct: 637 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 696
Query: 423 EDTPRESTEQGQDTEVKASDPHSMPEL--PRTAKQPPVPPPRKKRISRQL-ASTLPAPLE 479
P +T + + P + E+ P T K+P + +L A P LE
Sbjct: 697 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 756
Query: 480 NAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLG 539
N+ +TP P E + A T+ + ++P+ A+ ++
Sbjct: 757 NSPKEPGVPTTKTPAATKP-EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 815
Query: 540 VSVMATDQDSYSTSSTEEELEQFSSPSVK 568
S + T + TS+T ++ F ++K
Sbjct: 816 ESKI-TATTTQVTSTTTQDTTPFKITTLK 843
Score = 67.0 bits (162), Expect = 8e-11
Identities = 81/350 (23%), Positives = 122/350 (34%), Gaps = 42/350 (12%)
Query: 249 TDQPPLGNCPARPLPPTS--------DATSPTSRWAPRRPPPPPPVLPLQPC--SPAQPP 298
T + P P P P T+ + T++ AP P P P +P +P +P
Sbjct: 376 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 435
Query: 299 VLPALAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLR 355
PAP P PT+P PAP T P P P E P L P
Sbjct: 436 PTTPKKPAPTTPKEPAPTTPKEPAP-TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 494
Query: 356 EEAMKPGAASSPLQQVP---APPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLS 412
E + P P P AP P ++ PT P + + +P A
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTP-EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 553
Query: 413 LPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQ-LA 471
P + TP+E+ T K + P ++ E T + P P +++ +
Sbjct: 554 PAPTTPKEPAPTTPKETA----PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 609
Query: 472 STLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQ----HPPAQATAHSQSSPEF 527
+T P T + P P P+E +P + GT PA T + E
Sbjct: 610 TTCDKPAPTTPKGTAPTTPKEPAPTTPKE-PAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 668
Query: 528 -----KGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKKPS 572
KG ++ SD T +++ T+ E +P+ KKP+
Sbjct: 669 APTTTKGPTSTTSDK---PAPTTPKETAPTTPKE------PAPTTPKKPA 709
Score = 64.7 bits (156), Expect = 4e-10
Identities = 75/292 (25%), Positives = 110/292 (37%), Gaps = 34/292 (11%)
Query: 245 SALPTDQPPLGNCPARPLPPTSDATSPTS--RWAPRRPPPPPPVLPLQPCSPAQPPVLPA 302
+A T + P P P P T T+PT+ AP P P P L P + P +
Sbjct: 623 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTS 681
Query: 303 LAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAM 359
PAP P PT+P PAP TP P P P PP T E + PT P
Sbjct: 682 DKPAPTTPKETAPTTPKEPAP-TTPKKPAPTT-PETPPPTTSE-VSTPTTTKEPTTIH-K 737
Query: 360 KPGAASSPLQQVPAPPLPAKKNLPTAP----PRRRVSERVSLEDQSPGMAAEGDQLSLPP 415
P ++ L P P A +N P P + + + + + E D L P
Sbjct: 738 SPDESTPELSAEPTP--KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD-LRTTP 794
Query: 416 QGTSDGPEDTPRESTEQGQDTEVKA--------------SDPHSMPELPRTAKQPPVPPP 461
+ T+ P+ T +T + TE K + P + L T P V
Sbjct: 795 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 854
Query: 462 RKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHP 513
+K + ++ + P E A+ +A + TP P + ++P T+ P
Sbjct: 855 KKTITTTEI---MNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP 903
Score = 55.8 bits (133), Expect = 2e-07
Identities = 87/368 (23%), Positives = 126/368 (34%), Gaps = 55/368 (14%)
Query: 244 SSALPTDQPPLGNCPARPLPPTSDATSPTS--RWAP-----------RRPPPPPPVLP-- 288
++A T + P P P P T +PT+ AP + P P P P
Sbjct: 537 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596
Query: 289 --LQPCSPAQPPVLPALAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCER 343
L P + +P PAP P PT+P PAP TP P P P T +
Sbjct: 597 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP-TTPKEPAPTTPKGTAP--TTLK 653
Query: 344 LPCPTAGLGPLREEAMKPGAASSPLQQV---PAPPLPAKKNLPTAPPRRRVSERVSLEDQ 400
P PT P +E + P P PAP P K+ PT P E +
Sbjct: 654 EPAPTTPKKPAPKE-LAPTTTKGPTSTTSDKPAPTTP-KETAPTTP-----KEPAPTTPK 706
Query: 401 SPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPE---------LPR 451
P PP TS+ TP T + T + S S PE L
Sbjct: 707 KPAPTTP----ETPPPTTSE--VSTP---TTTKEPTTIHKSPDESTPELSAEPTPKALEN 757
Query: 452 TAKQPPVPPPRKKRISR-QLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGT 510
+ K+P VP + ++ ++ +T +L T ET T P ++ + T
Sbjct: 758 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP---ETTTAAPKMTKETATTTEKT 814
Query: 511 QHPPAQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKK 570
AT +S + + +L + +A + + T E+ + K K
Sbjct: 815 TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK 874
Query: 571 PSMILGKA 578
KA
Sbjct: 875 DRATNSKA 882
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/287 (21%), Positives = 98/287 (34%), Gaps = 48/287 (16%)
Query: 249 TDQPPLGNCPARPLPPTSDATSPTSRWAP----RRPPPPPPVLPLQPCSPAQPPVLPALA 304
T + P P P P TS+ ++PT+ P + P P L +P P L
Sbjct: 704 TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP----TPKALENSP 759
Query: 305 PAPACPLPTSPPVPAPHVTPHAPG---------PPDHPNQPPMMTCERLPCPTAGLGPLR 355
P P +P P +T A P+ P MT E T +
Sbjct: 760 KEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKE-TATTTEKTTESK 818
Query: 356 EEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPP 415
A S+ Q + K AP + ++ +
Sbjct: 819 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE---------------- 862
Query: 416 QGTSDGPEDT--PRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPP----PRKKRISRQ 469
+ PE+T P++ + T K P P+ P + K+P P P+ R+
Sbjct: 863 --IMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 920
Query: 470 LASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQ 516
+ ST+P L +AM L+T T R Q+P S+ +P ++
Sbjct: 921 MTSTMP-ELNPTSRIAEAM-LQTTT----RPNQTPNSKLVEVNPKSE 961
Score = 30.4 bits (67), Expect = 8.5
Identities = 27/144 (18%), Positives = 46/144 (31%), Gaps = 7/144 (4%)
Query: 378 AKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTE 437
AK PT+ + + + + P + + P+ + P +T + T
Sbjct: 184 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 243
Query: 438 VKASDPHSMPELPRTAKQP-------PVPPPRKKRISRQLASTLPAPLENAELCTQAMAL 490
K P + P T K+P P P K+ P ++A + A
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303
Query: 491 ETPTPGPPREGQSPASQAGTQHPP 514
TP P + PA + P
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTP 327
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 75.1 bits (183), Expect = 3e-13
Identities = 79/301 (26%), Positives = 105/301 (34%), Gaps = 25/301 (8%)
Query: 246 ALPTDQPPLGNCPARPLPPTSDATSPTS-RWAPRRPPPPPPVLPLQ-PCSPAQPPVLPAL 303
AL T + P P P T +PT+ + AP P P P P +P +P
Sbjct: 250 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 309
Query: 304 APAPACP---LPTSPPVPAPHVTPHAPGPPDHP----NQPPMMTCERLPCPTAGLGPLRE 356
PAP P PT+ PAP T AP P P + P T + P PT P
Sbjct: 310 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 369
Query: 357 EAMKPG-AASSPLQQVPAPPLPA--KKNLPT-----APPRRRVSERVSLEDQSPGMAAEG 408
+P P P P P KK PT AP + + ++ SP E
Sbjct: 370 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 429
Query: 409 DQLSLPPQGTSDGPEDT--PRESTEQGQDTEVKASDPHSMPE-LPRTAKQPPVPPPRKKR 465
P T P T P +T + T K P + E P T K+P P+K
Sbjct: 430 -----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 484
Query: 466 ISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSP 525
+ P E A T+ A TP P + A + P + ++P
Sbjct: 485 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 544
Query: 526 E 526
E
Sbjct: 545 E 545
Score = 73.2 bits (178), Expect = 1e-12
Identities = 75/293 (25%), Positives = 104/293 (35%), Gaps = 20/293 (6%)
Query: 245 SALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALA 304
SA T + P P +P P T +PT+ P+ P P P P P A
Sbjct: 334 SAPTTPKEPAPTTPKKPAPTTPKEPAPTT---PKEPTPTTPKEPAPTTKEPAPTTPKEPA 390
Query: 305 P-APACPLPTSPPVPAPHVTPHAPGP-------PDHPNQPPMMTCERLPCPTAGLGP--L 354
P AP P PT+P PAP TP P P P P +P T + P T P
Sbjct: 391 PTAPKKPAPTTPKEPAP-TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449
Query: 355 REEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLP 414
+ P S + PAP P K+ PT P + + +P A
Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 508
Query: 415 PQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVP-PPRKKRISRQLAST 473
P + TP+E+ T K P + +L T + P P P + + T
Sbjct: 509 PTTPKEPAPTTPKETA----PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564
Query: 474 LPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPE 526
P E A +A A TP P + PA + P + ++P+
Sbjct: 565 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 617
Score = 70.9 bits (172), Expect = 6e-12
Identities = 77/329 (23%), Positives = 119/329 (36%), Gaps = 22/329 (6%)
Query: 258 PARPLPPTSDATSPTS--RWAPRRPPPPPPVLPLQPC--SPAQPPVLPALAPAPACPLPT 313
P P P T + +PT+ AP P P P P +P +P +P AP P T
Sbjct: 560 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 619
Query: 314 SPPV---PAPHVTPHAPGP----PDHPNQPPMMTCERLPCPTA--GLGPLREEAMKPGAA 364
+P PAP TP P P P +P TC++ P PT G P + P
Sbjct: 620 APTTLKEPAP-TTPKKPAPKELAPTTTKEPTSTTCDK-PAPTTPKGTAPTTPKEPAPTTP 677
Query: 365 SSPLQQVP--APPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGP 422
P P P K+ PT P + E + P P+ T+
Sbjct: 678 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 737
Query: 423 EDTPRESTEQGQDTEVKASDPHSMPEL--PRTAKQPPVPPPRKKRISRQL-ASTLPAPLE 479
P +T + + P + E+ P T K+P + +L A P LE
Sbjct: 738 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 797
Query: 480 NAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLG 539
N+ +TP P E + A T+ + ++P+ A+ ++
Sbjct: 798 NSPKEPGVPTTKTPAATKP-EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 856
Query: 540 VSVMATDQDSYSTSSTEEELEQFSSPSVK 568
S + T + TS+T ++ F ++K
Sbjct: 857 ESKI-TATTTQVTSTTTQDTTPFKITTLK 884
Score = 67.0 bits (162), Expect = 8e-11
Identities = 81/350 (23%), Positives = 122/350 (34%), Gaps = 42/350 (12%)
Query: 249 TDQPPLGNCPARPLPPTS--------DATSPTSRWAPRRPPPPPPVLPLQPC--SPAQPP 298
T + P P P P T+ + T++ AP P P P +P +P +P
Sbjct: 417 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 476
Query: 299 VLPALAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLR 355
PAP P PT+P PAP T P P P E P L P
Sbjct: 477 PTTPKKPAPTTPKEPAPTTPKEPAP-TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 535
Query: 356 EEAMKPGAASSPLQQVP---APPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLS 412
E + P P P AP P ++ PT P + + +P A
Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTP-EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 594
Query: 413 LPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQ-LA 471
P + TP+E+ T K + P ++ E T + P P +++ +
Sbjct: 595 PAPTTPKEPAPTTPKETA----PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 650
Query: 472 STLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQ----HPPAQATAHSQSSPEF 527
+T P T + P P P+E +P + GT PA T + E
Sbjct: 651 TTCDKPAPTTPKGTAPTTPKEPAPTTPKE-PAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 709
Query: 528 -----KGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKKPS 572
KG ++ SD T +++ T+ E +P+ KKP+
Sbjct: 710 APTTTKGPTSTTSDK---PAPTTPKETAPTTPKE------PAPTTPKKPA 750
Score = 64.7 bits (156), Expect = 4e-10
Identities = 75/292 (25%), Positives = 110/292 (37%), Gaps = 34/292 (11%)
Query: 245 SALPTDQPPLGNCPARPLPPTSDATSPTS--RWAPRRPPPPPPVLPLQPCSPAQPPVLPA 302
+A T + P P P P T T+PT+ AP P P P L P + P +
Sbjct: 664 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTS 722
Query: 303 LAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAM 359
PAP P PT+P PAP TP P P P PP T E + PT P
Sbjct: 723 DKPAPTTPKETAPTTPKEPAP-TTPKKPAPTT-PETPPPTTSE-VSTPTTTKEPTTIH-K 778
Query: 360 KPGAASSPLQQVPAPPLPAKKNLPTAP----PRRRVSERVSLEDQSPGMAAEGDQLSLPP 415
P ++ L P P A +N P P + + + + + E D L P
Sbjct: 779 SPDESTPELSAEPTP--KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD-LRTTP 835
Query: 416 QGTSDGPEDTPRESTEQGQDTEVKA--------------SDPHSMPELPRTAKQPPVPPP 461
+ T+ P+ T +T + TE K + P + L T P V
Sbjct: 836 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 895
Query: 462 RKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHP 513
+K + ++ + P E A+ +A + TP P + ++P T+ P
Sbjct: 896 KKTITTTEI---MNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP 944
Score = 55.8 bits (133), Expect = 2e-07
Identities = 87/368 (23%), Positives = 126/368 (34%), Gaps = 55/368 (14%)
Query: 244 SSALPTDQPPLGNCPARPLPPTSDATSPTS--RWAP-----------RRPPPPPPVLP-- 288
++A T + P P P P T +PT+ AP + P P P P
Sbjct: 578 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637
Query: 289 --LQPCSPAQPPVLPALAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCER 343
L P + +P PAP P PT+P PAP TP P P P T +
Sbjct: 638 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP-TTPKEPAPTTPKGTAP--TTLK 694
Query: 344 LPCPTAGLGPLREEAMKPGAASSPLQQV---PAPPLPAKKNLPTAPPRRRVSERVSLEDQ 400
P PT P +E + P P PAP P K+ PT P E +
Sbjct: 695 EPAPTTPKKPAPKE-LAPTTTKGPTSTTSDKPAPTTP-KETAPTTP-----KEPAPTTPK 747
Query: 401 SPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPE---------LPR 451
P PP TS+ TP T + T + S S PE L
Sbjct: 748 KPAPTTP----ETPPPTTSE--VSTP---TTTKEPTTIHKSPDESTPELSAEPTPKALEN 798
Query: 452 TAKQPPVPPPRKKRISR-QLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGT 510
+ K+P VP + ++ ++ +T +L T ET T P ++ + T
Sbjct: 799 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP---ETTTAAPKMTKETATTTEKT 855
Query: 511 QHPPAQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKK 570
AT +S + + +L + +A + + T E+ + K K
Sbjct: 856 TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK 915
Query: 571 PSMILGKA 578
KA
Sbjct: 916 DRATNSKA 923
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/287 (21%), Positives = 98/287 (34%), Gaps = 48/287 (16%)
Query: 249 TDQPPLGNCPARPLPPTSDATSPTSRWAP----RRPPPPPPVLPLQPCSPAQPPVLPALA 304
T + P P P P TS+ ++PT+ P + P P L +P P L
Sbjct: 745 TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP----TPKALENSP 800
Query: 305 PAPACPLPTSPPVPAPHVTPHAPG---------PPDHPNQPPMMTCERLPCPTAGLGPLR 355
P P +P P +T A P+ P MT E T +
Sbjct: 801 KEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKE-TATTTEKTTESK 859
Query: 356 EEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPP 415
A S+ Q + K AP + ++ +
Sbjct: 860 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE---------------- 903
Query: 416 QGTSDGPEDT--PRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPP----PRKKRISRQ 469
+ PE+T P++ + T K P P+ P + K+P P P+ R+
Sbjct: 904 --IMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 961
Query: 470 LASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQ 516
+ ST+P L +AM L+T T R Q+P S+ +P ++
Sbjct: 962 MTSTMP-ELNPTSRIAEAM-LQTTT----RPNQTPNSKLVEVNPKSE 1002
Score = 30.4 bits (67), Expect = 8.5
Identities = 27/144 (18%), Positives = 46/144 (31%), Gaps = 7/144 (4%)
Query: 378 AKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTE 437
AK PT+ + + + + P + + P+ + P +T + T
Sbjct: 225 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 284
Query: 438 VKASDPHSMPELPRTAKQP-------PVPPPRKKRISRQLASTLPAPLENAELCTQAMAL 490
K P + P T K+P P P K+ P ++A + A
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344
Query: 491 ETPTPGPPREGQSPASQAGTQHPP 514
TP P + PA + P
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTP 368
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 75.1 bits (183), Expect = 3e-13
Identities = 79/301 (26%), Positives = 105/301 (34%), Gaps = 25/301 (8%)
Query: 246 ALPTDQPPLGNCPARPLPPTSDATSPTS-RWAPRRPPPPPPVLPLQ-PCSPAQPPVLPAL 303
AL T + P P P T +PT+ + AP P P P P +P +P
Sbjct: 302 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 361
Query: 304 APAPACP---LPTSPPVPAPHVTPHAPGPPDHP----NQPPMMTCERLPCPTAGLGPLRE 356
PAP P PT+ PAP T AP P P + P T + P PT P
Sbjct: 362 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 421
Query: 357 EAMKPG-AASSPLQQVPAPPLPA--KKNLPT-----APPRRRVSERVSLEDQSPGMAAEG 408
+P P P P P KK PT AP + + ++ SP E
Sbjct: 422 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 481
Query: 409 DQLSLPPQGTSDGPEDT--PRESTEQGQDTEVKASDPHSMPE-LPRTAKQPPVPPPRKKR 465
P T P T P +T + T K P + E P T K+P P+K
Sbjct: 482 -----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 536
Query: 466 ISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSP 525
+ P E A T+ A TP P + A + P + ++P
Sbjct: 537 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 596
Query: 526 E 526
E
Sbjct: 597 E 597
Score = 73.2 bits (178), Expect = 1e-12
Identities = 75/293 (25%), Positives = 104/293 (35%), Gaps = 20/293 (6%)
Query: 245 SALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALA 304
SA T + P P +P P T +PT+ P+ P P P P P A
Sbjct: 386 SAPTTPKEPAPTTPKKPAPTTPKEPAPTT---PKEPTPTTPKEPAPTTKEPAPTTPKEPA 442
Query: 305 P-APACPLPTSPPVPAPHVTPHAPGP-------PDHPNQPPMMTCERLPCPTAGLGP--L 354
P AP P PT+P PAP TP P P P P +P T + P T P
Sbjct: 443 PTAPKKPAPTTPKEPAP-TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501
Query: 355 REEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLP 414
+ P S + PAP P K+ PT P + + +P A
Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 560
Query: 415 PQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVP-PPRKKRISRQLAST 473
P + TP+E+ T K P + +L T + P P P + + T
Sbjct: 561 PTTPKEPAPTTPKETA----PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616
Query: 474 LPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPE 526
P E A +A A TP P + PA + P + ++P+
Sbjct: 617 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 669
Score = 70.9 bits (172), Expect = 6e-12
Identities = 77/329 (23%), Positives = 119/329 (36%), Gaps = 22/329 (6%)
Query: 258 PARPLPPTSDATSPTS--RWAPRRPPPPPPVLPLQPC--SPAQPPVLPALAPAPACPLPT 313
P P P T + +PT+ AP P P P P +P +P +P AP P T
Sbjct: 612 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 671
Query: 314 SPPV---PAPHVTPHAPGP----PDHPNQPPMMTCERLPCPTA--GLGPLREEAMKPGAA 364
+P PAP TP P P P +P TC++ P PT G P + P
Sbjct: 672 APTTLKEPAP-TTPKKPAPKELAPTTTKEPTSTTCDK-PAPTTPKGTAPTTPKEPAPTTP 729
Query: 365 SSPLQQVP--APPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGP 422
P P P K+ PT P + E + P P+ T+
Sbjct: 730 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 789
Query: 423 EDTPRESTEQGQDTEVKASDPHSMPEL--PRTAKQPPVPPPRKKRISRQL-ASTLPAPLE 479
P +T + + P + E+ P T K+P + +L A P LE
Sbjct: 790 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 849
Query: 480 NAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLG 539
N+ +TP P E + A T+ + ++P+ A+ ++
Sbjct: 850 NSPKEPGVPTTKTPAATKP-EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 908
Query: 540 VSVMATDQDSYSTSSTEEELEQFSSPSVK 568
S + T + TS+T ++ F ++K
Sbjct: 909 ESKI-TATTTQVTSTTTQDTTPFKITTLK 936
Score = 67.0 bits (162), Expect = 8e-11
Identities = 81/350 (23%), Positives = 122/350 (34%), Gaps = 42/350 (12%)
Query: 249 TDQPPLGNCPARPLPPTS--------DATSPTSRWAPRRPPPPPPVLPLQPC--SPAQPP 298
T + P P P P T+ + T++ AP P P P +P +P +P
Sbjct: 469 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 528
Query: 299 VLPALAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLR 355
PAP P PT+P PAP T P P P E P L P
Sbjct: 529 PTTPKKPAPTTPKEPAPTTPKEPAP-TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587
Query: 356 EEAMKPGAASSPLQQVP---APPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLS 412
E + P P P AP P ++ PT P + + +P A
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTP-EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 646
Query: 413 LPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQ-LA 471
P + TP+E+ T K + P ++ E T + P P +++ +
Sbjct: 647 PAPTTPKEPAPTTPKETA----PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 702
Query: 472 STLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQ----HPPAQATAHSQSSPEF 527
+T P T + P P P+E +P + GT PA T + E
Sbjct: 703 TTCDKPAPTTPKGTAPTTPKEPAPTTPKE-PAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 761
Query: 528 -----KGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKKPS 572
KG ++ SD T +++ T+ E +P+ KKP+
Sbjct: 762 APTTTKGPTSTTSDK---PAPTTPKETAPTTPKE------PAPTTPKKPA 802
Score = 64.7 bits (156), Expect = 4e-10
Identities = 75/292 (25%), Positives = 110/292 (37%), Gaps = 34/292 (11%)
Query: 245 SALPTDQPPLGNCPARPLPPTSDATSPTS--RWAPRRPPPPPPVLPLQPCSPAQPPVLPA 302
+A T + P P P P T T+PT+ AP P P P L P + P +
Sbjct: 716 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTS 774
Query: 303 LAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAM 359
PAP P PT+P PAP TP P P P PP T E + PT P
Sbjct: 775 DKPAPTTPKETAPTTPKEPAP-TTPKKPAPTT-PETPPPTTSE-VSTPTTTKEPTTIH-K 830
Query: 360 KPGAASSPLQQVPAPPLPAKKNLPTAP----PRRRVSERVSLEDQSPGMAAEGDQLSLPP 415
P ++ L P P A +N P P + + + + + E D L P
Sbjct: 831 SPDESTPELSAEPTP--KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD-LRTTP 887
Query: 416 QGTSDGPEDTPRESTEQGQDTEVKA--------------SDPHSMPELPRTAKQPPVPPP 461
+ T+ P+ T +T + TE K + P + L T P V
Sbjct: 888 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 947
Query: 462 RKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHP 513
+K + ++ + P E A+ +A + TP P + ++P T+ P
Sbjct: 948 KKTITTTEI---MNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP 996
Score = 55.8 bits (133), Expect = 2e-07
Identities = 87/368 (23%), Positives = 126/368 (34%), Gaps = 55/368 (14%)
Query: 244 SSALPTDQPPLGNCPARPLPPTSDATSPTS--RWAP-----------RRPPPPPPVLP-- 288
++A T + P P P P T +PT+ AP + P P P P
Sbjct: 630 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689
Query: 289 --LQPCSPAQPPVLPALAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCER 343
L P + +P PAP P PT+P PAP TP P P P T +
Sbjct: 690 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP-TTPKEPAPTTPKGTAP--TTLK 746
Query: 344 LPCPTAGLGPLREEAMKPGAASSPLQQV---PAPPLPAKKNLPTAPPRRRVSERVSLEDQ 400
P PT P +E + P P PAP P K+ PT P E +
Sbjct: 747 EPAPTTPKKPAPKE-LAPTTTKGPTSTTSDKPAPTTP-KETAPTTP-----KEPAPTTPK 799
Query: 401 SPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPE---------LPR 451
P PP TS+ TP T + T + S S PE L
Sbjct: 800 KPAPTTP----ETPPPTTSE--VSTP---TTTKEPTTIHKSPDESTPELSAEPTPKALEN 850
Query: 452 TAKQPPVPPPRKKRISR-QLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGT 510
+ K+P VP + ++ ++ +T +L T ET T P ++ + T
Sbjct: 851 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP---ETTTAAPKMTKETATTTEKT 907
Query: 511 QHPPAQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKK 570
AT +S + + +L + +A + + T E+ + K K
Sbjct: 908 TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK 967
Query: 571 PSMILGKA 578
KA
Sbjct: 968 DRATNSKA 975
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/287 (21%), Positives = 98/287 (34%), Gaps = 48/287 (16%)
Query: 249 TDQPPLGNCPARPLPPTSDATSPTSRWAP----RRPPPPPPVLPLQPCSPAQPPVLPALA 304
T + P P P P TS+ ++PT+ P + P P L +P P L
Sbjct: 797 TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP----TPKALENSP 852
Query: 305 PAPACPLPTSPPVPAPHVTPHAPG---------PPDHPNQPPMMTCERLPCPTAGLGPLR 355
P P +P P +T A P+ P MT E T +
Sbjct: 853 KEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKE-TATTTEKTTESK 911
Query: 356 EEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPP 415
A S+ Q + K AP + ++ +
Sbjct: 912 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE---------------- 955
Query: 416 QGTSDGPEDT--PRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPP----PRKKRISRQ 469
+ PE+T P++ + T K P P+ P + K+P P P+ R+
Sbjct: 956 --IMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1013
Query: 470 LASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQ 516
+ ST+P L +AM L+T T R Q+P S+ +P ++
Sbjct: 1014 MTSTMP-ELNPTSRIAEAM-LQTTT----RPNQTPNSKLVEVNPKSE 1054
Score = 30.4 bits (67), Expect = 8.5
Identities = 27/144 (18%), Positives = 46/144 (31%), Gaps = 7/144 (4%)
Query: 378 AKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTE 437
AK PT+ + + + + P + + P+ + P +T + T
Sbjct: 277 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 336
Query: 438 VKASDPHSMPELPRTAKQP-------PVPPPRKKRISRQLASTLPAPLENAELCTQAMAL 490
K P + P T K+P P P K+ P ++A + A
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396
Query: 491 ETPTPGPPREGQSPASQAGTQHPP 514
TP P + PA + P
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTP 420
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 75.1 bits (183), Expect = 3e-13
Identities = 79/301 (26%), Positives = 105/301 (34%), Gaps = 25/301 (8%)
Query: 246 ALPTDQPPLGNCPARPLPPTSDATSPTS-RWAPRRPPPPPPVLPLQ-PCSPAQPPVLPAL 303
AL T + P P P T +PT+ + AP P P P P +P +P
Sbjct: 343 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 402
Query: 304 APAPACP---LPTSPPVPAPHVTPHAPGPPDHP----NQPPMMTCERLPCPTAGLGPLRE 356
PAP P PT+ PAP T AP P P + P T + P PT P
Sbjct: 403 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 462
Query: 357 EAMKPG-AASSPLQQVPAPPLPA--KKNLPT-----APPRRRVSERVSLEDQSPGMAAEG 408
+P P P P P KK PT AP + + ++ SP E
Sbjct: 463 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 522
Query: 409 DQLSLPPQGTSDGPEDT--PRESTEQGQDTEVKASDPHSMPE-LPRTAKQPPVPPPRKKR 465
P T P T P +T + T K P + E P T K+P P+K
Sbjct: 523 -----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 577
Query: 466 ISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSP 525
+ P E A T+ A TP P + A + P + ++P
Sbjct: 578 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 637
Query: 526 E 526
E
Sbjct: 638 E 638
Score = 73.2 bits (178), Expect = 1e-12
Identities = 75/293 (25%), Positives = 104/293 (35%), Gaps = 20/293 (6%)
Query: 245 SALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALA 304
SA T + P P +P P T +PT+ P+ P P P P P A
Sbjct: 427 SAPTTPKEPAPTTPKKPAPTTPKEPAPTT---PKEPTPTTPKEPAPTTKEPAPTTPKEPA 483
Query: 305 P-APACPLPTSPPVPAPHVTPHAPGP-------PDHPNQPPMMTCERLPCPTAGLGP--L 354
P AP P PT+P PAP TP P P P P +P T + P T P
Sbjct: 484 PTAPKKPAPTTPKEPAP-TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542
Query: 355 REEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLP 414
+ P S + PAP P K+ PT P + + +P A
Sbjct: 543 KSAPTTPKEPSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 601
Query: 415 PQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVP-PPRKKRISRQLAST 473
P + TP+E+ T K P + +L T + P P P + + T
Sbjct: 602 PTTPKEPAPTTPKETA----PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657
Query: 474 LPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPE 526
P E A +A A TP P + PA + P + ++P+
Sbjct: 658 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 710
Score = 70.9 bits (172), Expect = 6e-12
Identities = 77/329 (23%), Positives = 119/329 (36%), Gaps = 22/329 (6%)
Query: 258 PARPLPPTSDATSPTS--RWAPRRPPPPPPVLPLQPC--SPAQPPVLPALAPAPACPLPT 313
P P P T + +PT+ AP P P P P +P +P +P AP P T
Sbjct: 653 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 712
Query: 314 SPPV---PAPHVTPHAPGP----PDHPNQPPMMTCERLPCPTA--GLGPLREEAMKPGAA 364
+P PAP TP P P P +P TC++ P PT G P + P
Sbjct: 713 APTTLKEPAP-TTPKKPAPKELAPTTTKEPTSTTCDK-PAPTTPKGTAPTTPKEPAPTTP 770
Query: 365 SSPLQQVP--APPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGP 422
P P P K+ PT P + E + P P+ T+
Sbjct: 771 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 830
Query: 423 EDTPRESTEQGQDTEVKASDPHSMPEL--PRTAKQPPVPPPRKKRISRQL-ASTLPAPLE 479
P +T + + P + E+ P T K+P + +L A P LE
Sbjct: 831 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 890
Query: 480 NAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLG 539
N+ +TP P E + A T+ + ++P+ A+ ++
Sbjct: 891 NSPKEPGVPTTKTPAATKP-EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 949
Query: 540 VSVMATDQDSYSTSSTEEELEQFSSPSVK 568
S + T + TS+T ++ F ++K
Sbjct: 950 ESKI-TATTTQVTSTTTQDTTPFKITTLK 977
Score = 67.0 bits (162), Expect = 8e-11
Identities = 81/350 (23%), Positives = 122/350 (34%), Gaps = 42/350 (12%)
Query: 249 TDQPPLGNCPARPLPPTS--------DATSPTSRWAPRRPPPPPPVLPLQPC--SPAQPP 298
T + P P P P T+ + T++ AP P P P +P +P +P
Sbjct: 510 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 569
Query: 299 VLPALAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLR 355
PAP P PT+P PAP T P P P E P L P
Sbjct: 570 PTTPKKPAPTTPKEPAPTTPKEPAP-TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628
Query: 356 EEAMKPGAASSPLQQVP---APPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLS 412
E + P P P AP P ++ PT P + + +P A
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTP-EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 687
Query: 413 LPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQ-LA 471
P + TP+E+ T K + P ++ E T + P P +++ +
Sbjct: 688 PAPTTPKEPAPTTPKETA----PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 743
Query: 472 STLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQ----HPPAQATAHSQSSPEF 527
+T P T + P P P+E +P + GT PA T + E
Sbjct: 744 TTCDKPAPTTPKGTAPTTPKEPAPTTPKE-PAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 802
Query: 528 -----KGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKKPS 572
KG ++ SD T +++ T+ E +P+ KKP+
Sbjct: 803 APTTTKGPTSTTSDK---PAPTTPKETAPTTPKE------PAPTTPKKPA 843
Score = 64.7 bits (156), Expect = 4e-10
Identities = 75/292 (25%), Positives = 110/292 (37%), Gaps = 34/292 (11%)
Query: 245 SALPTDQPPLGNCPARPLPPTSDATSPTS--RWAPRRPPPPPPVLPLQPCSPAQPPVLPA 302
+A T + P P P P T T+PT+ AP P P P L P + P +
Sbjct: 757 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTS 815
Query: 303 LAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAM 359
PAP P PT+P PAP TP P P P PP T E + PT P
Sbjct: 816 DKPAPTTPKETAPTTPKEPAP-TTPKKPAPTT-PETPPPTTSE-VSTPTTTKEPTTIH-K 871
Query: 360 KPGAASSPLQQVPAPPLPAKKNLPTAP----PRRRVSERVSLEDQSPGMAAEGDQLSLPP 415
P ++ L P P A +N P P + + + + + E D L P
Sbjct: 872 SPDESTPELSAEPTP--KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD-LRTTP 928
Query: 416 QGTSDGPEDTPRESTEQGQDTEVKA--------------SDPHSMPELPRTAKQPPVPPP 461
+ T+ P+ T +T + TE K + P + L T P V
Sbjct: 929 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 988
Query: 462 RKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHP 513
+K + ++ + P E A+ +A + TP P + ++P T+ P
Sbjct: 989 KKTITTTEI---MNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP 1037
Score = 55.8 bits (133), Expect = 2e-07
Identities = 87/368 (23%), Positives = 126/368 (34%), Gaps = 55/368 (14%)
Query: 244 SSALPTDQPPLGNCPARPLPPTSDATSPTS--RWAP-----------RRPPPPPPVLP-- 288
++A T + P P P P T +PT+ AP + P P P P
Sbjct: 671 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730
Query: 289 --LQPCSPAQPPVLPALAPAPACP---LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCER 343
L P + +P PAP P PT+P PAP TP P P P T +
Sbjct: 731 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP-TTPKEPAPTTPKGTAP--TTLK 787
Query: 344 LPCPTAGLGPLREEAMKPGAASSPLQQV---PAPPLPAKKNLPTAPPRRRVSERVSLEDQ 400
P PT P +E + P P PAP P K+ PT P E +
Sbjct: 788 EPAPTTPKKPAPKE-LAPTTTKGPTSTTSDKPAPTTP-KETAPTTP-----KEPAPTTPK 840
Query: 401 SPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPE---------LPR 451
P PP TS+ TP T + T + S S PE L
Sbjct: 841 KPAPTTP----ETPPPTTSE--VSTP---TTTKEPTTIHKSPDESTPELSAEPTPKALEN 891
Query: 452 TAKQPPVPPPRKKRISR-QLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGT 510
+ K+P VP + ++ ++ +T +L T ET T P ++ + T
Sbjct: 892 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP---ETTTAAPKMTKETATTTEKT 948
Query: 511 QHPPAQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKK 570
AT +S + + +L + +A + + T E+ + K K
Sbjct: 949 TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK 1008
Query: 571 PSMILGKA 578
KA
Sbjct: 1009 DRATNSKA 1016
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/287 (21%), Positives = 98/287 (34%), Gaps = 48/287 (16%)
Query: 249 TDQPPLGNCPARPLPPTSDATSPTSRWAP----RRPPPPPPVLPLQPCSPAQPPVLPALA 304
T + P P P P TS+ ++PT+ P + P P L +P P L
Sbjct: 838 TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP----TPKALENSP 893
Query: 305 PAPACPLPTSPPVPAPHVTPHAPG---------PPDHPNQPPMMTCERLPCPTAGLGPLR 355
P P +P P +T A P+ P MT E T +
Sbjct: 894 KEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKE-TATTTEKTTESK 952
Query: 356 EEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPP 415
A S+ Q + K AP + ++ +
Sbjct: 953 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE---------------- 996
Query: 416 QGTSDGPEDT--PRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPP----PRKKRISRQ 469
+ PE+T P++ + T K P P+ P + K+P P P+ R+
Sbjct: 997 --IMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1054
Query: 470 LASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQ 516
+ ST+P L +AM L+T T R Q+P S+ +P ++
Sbjct: 1055 MTSTMP-ELNPTSRIAEAM-LQTTT----RPNQTPNSKLVEVNPKSE 1095
Score = 30.4 bits (67), Expect = 8.5
Identities = 27/144 (18%), Positives = 46/144 (31%), Gaps = 7/144 (4%)
Query: 378 AKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTE 437
AK PT+ + + + + P + + P+ + P +T + T
Sbjct: 318 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 377
Query: 438 VKASDPHSMPELPRTAKQP-------PVPPPRKKRISRQLASTLPAPLENAELCTQAMAL 490
K P + P T K+P P P K+ P ++A + A
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437
Query: 491 ETPTPGPPREGQSPASQAGTQHPP 514
TP P + PA + P
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTP 461
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 73.9 bits (180), Expect = 7e-13
Identities = 106/442 (23%), Positives = 153/442 (34%), Gaps = 93/442 (21%)
Query: 186 PPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIE-DCS 244
PP P PP P PL S P+A A P+F++
Sbjct: 629 PPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA------------------APMFVKYSTI 670
Query: 245 SALPTDQPPLGNCPARPLPPTSDATS-------PTSRWAPRRPPPPPPVLPLQPCSPAQP 297
+ L G P PP + S P + P PPPPPP P + +P
Sbjct: 671 TRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKP 730
Query: 298 -PVLPALAPAPACPLP-----------TSPPVPAPHVTPHAPGPPDHPNQP--------- 336
P P+L A P P +PP P P AP PP P +P
Sbjct: 731 APCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTS 790
Query: 337 -----PMMTCERLPCPTAGLGPLREEAMKPGA---ASSPLQQVPAPP--LPAKKNLPTAP 386
P++T P PT + P +++ P + S P VP PP LP +++ P
Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKP 850
Query: 387 PRRRVS------ERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPR-ESTEQGQDTEVK 439
P +S ++++ + P + L P + P+ P ++ + Q + +
Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910
Query: 440 ASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCTQAMALETPTP---G 496
P P P ++ P PPP S +PAP +PTP G
Sbjct: 911 VPSPDFPPPPPESSLVFPPPPP----------SPVPAP------PPPPPPTASPTPDKSG 954
Query: 497 PPREGQSPASQAGTQHPP----AQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSYST 552
P + S S G + PP ++ S S E DSL VS +S S
Sbjct: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL-VSKFTPPAESGSP 1013
Query: 553 SSTEEELEQFSSPSVKKKPSMI 574
S E P+ KP +
Sbjct: 1014 SK-----ETLPPPAAPPKPGKL 1030
Score = 69.3 bits (168), Expect = 2e-11
Identities = 78/298 (26%), Positives = 109/298 (36%), Gaps = 41/298 (13%)
Query: 252 PPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPL 311
PPL P P T+ SP P PPPPPP P P P PP+ AP+
Sbjct: 607 PPLSPQPKIVTPYTASQPSP-----PLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAA 661
Query: 312 PT----SPPVPAPHVTPHAPGPPDHPNQPPMMTCE----RLPCPTAGLGPLREEAMKPGA 363
P S + + H+ G P PP+M + ++ P G+ P P
Sbjct: 662 PMFVKYSTITRLQNASQHS-GALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 364 ASSPLQQV-PAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQL--SLPPQGTSD 420
S + Q+ PAP P+ PP ++ + + +P + LPPQ
Sbjct: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK 780
Query: 421 GPEDTPR-ESTEQGQDTEVKASDPHSMPELPRTAKQP----------------PVPPPRK 463
P ST+ +A+ P P +P KQP PVPPP
Sbjct: 781 PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL 840
Query: 464 KRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQS------PASQAGTQHPPA 515
+ A P+PL + +A + P P P +S PA+ A Q PPA
Sbjct: 841 PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVA-PQSPPA 897
Score = 60.5 bits (145), Expect = 8e-09
Identities = 75/252 (29%), Positives = 93/252 (36%), Gaps = 53/252 (21%)
Query: 291 PCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQ--------PPMM--- 339
P SP V P A P+ PLP PP P P P P PP P+Q PM
Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667
Query: 340 -TCERLPCPTAGLGPL---------REEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRR 389
T RL + G L + +++KP P VP PP P PP
Sbjct: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP-------PPPPPPT 720
Query: 390 RVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPEL 449
S L+ A Q S PP P + + T+V P P +
Sbjct: 721 PGSAMAQLKPAP--CAPSLPQFSAPP---------PPLKIHQVQHITQVAPPTPPPPPPI 769
Query: 450 PRTAKQPPVPPPRKKRISRQLASTLPAPLEN---AELCTQAMALETPTPGPPREGQSPAS 506
P A PP PP+ T+PAP A + TQA A TPTP P + PA
Sbjct: 770 P--APLPPQAPPKP-------LVTIPAPTSTKTVAPVVTQA-APPTPTPPVPPAKKQPAF 819
Query: 507 QAGTQHPPAQAT 518
A + PP+ T
Sbjct: 820 PA-SYIPPSPPT 830
Score = 60.1 bits (144), Expect = 1e-08
Identities = 67/326 (20%), Positives = 102/326 (31%), Gaps = 45/326 (13%)
Query: 247 LPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSP------------ 294
LP Q P PL P + P PPP PP + QP P
Sbjct: 840 LPKQQSFCAKPPPSPLSPVPSVVKQIASQFP--PPPTPPAMESQPLKPVPANVAPQSPPA 897
Query: 295 --AQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLG 352
A+P P+ P P+ P PP + P P P P PP T P + G
Sbjct: 898 VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPG 957
Query: 353 PLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLS 412
+ PG P + + P+R + + + P + + +
Sbjct: 958 KKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKET 1017
Query: 413 LPPQGTSDGPEDTPRESTE-------------------QGQDTEVKASDPHSMPELPRTA 453
LPP P +G+D+ V+ P S + P
Sbjct: 1018 LPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPP 1077
Query: 454 KQPPVPPPR-------KKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPAS 506
+ +P P S ++A P P + +++ ++ P P R + +
Sbjct: 1078 PETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKM---SVKKAPPPTRPKRNDSTRLT 1134
Query: 507 QAGTQHPPAQATAHSQSSPEFKGSLA 532
QA P AT Q K SL+
Sbjct: 1135 QAEISEQPTMATVVPQVPTSPKSSLS 1160
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 73.2 bits (178), Expect = 1e-12
Identities = 95/351 (27%), Positives = 127/351 (36%), Gaps = 60/351 (17%)
Query: 187 PQERGKP---AEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDC 243
PQER + AE P P +VS+ P A D A + G + P +
Sbjct: 701 PQERSQQPLSAEGPHLSVPASVIVSA-PPPAQDPAPATPVAKGAG------LGPQAPDSQ 753
Query: 244 SSALPTDQPPLGNCPARPLPPTSDATSPTSRW---APRRPPP----PPPVLPLQPCSPAQ 296
+S P Q P P + P+S + P +P P P PP P +P S ++
Sbjct: 754 ASPAPAPQIPAA-APLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSR 812
Query: 297 PPVLPALAPAPACPLPTSPP-VPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLR 355
PP P L P CP P +PP +P V + G P PP P PTA GP
Sbjct: 813 PPSEPPLHP---CPPPQAPPTLPGIFVIQNQLGVP-----PPASN----PAPTAP-GP-- 857
Query: 356 EEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPP 415
P P Q P PLP +LP + V+ + P QL PP
Sbjct: 858 -----PQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPP 912
Query: 416 QGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLP 475
S GP +P + P ++ +P A PP PPPR ++ LP
Sbjct: 913 ---SQGPHKSP--------------TPPPTLHLVPEPAAPPP-PPPRTFQMVTTPFPALP 954
Query: 476 AP---LENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQS 523
P LE + L+ G P Q+ S P A Q+
Sbjct: 955 QPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQA 1005
Score = 63.5 bits (153), Expect = 9e-10
Identities = 105/420 (25%), Positives = 143/420 (34%), Gaps = 132/420 (31%)
Query: 244 SSALPTDQPPLGNCPARPLP-PTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQ-PPVLP 301
S +LP Q PLG+ P P P PT + P SR P+ PP PL PC P Q PP LP
Sbjct: 776 SPSLP-HQAPLGDSPHLPSPHPTRPPSRPPSR--PQSVSRPPSEPPLHPCPPPQAPPTLP 832
Query: 302 ALA--------------PAPACPLPTSPPV------------PAPHVTPHAP-------- 327
+ PAP P P PP+ PAPH+ P +
Sbjct: 833 GIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSS 892
Query: 328 ----------------------GPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAAS 365
GP P PP T +P P A P +
Sbjct: 893 ETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPP--TLHLVPEPAA--------PPPPPPRT 942
Query: 366 SPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDT 425
+ P P LP K L +V + L++++ G A P TS GP +
Sbjct: 943 FQMVTTPFPALPQPKAL--LERFHQVPSGIILQNKAGGAPA------APQTSTSLGPLTS 994
Query: 426 PRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCT 485
P S V P P P A P P P +A+T PL AE
Sbjct: 995 PAAS------VLVSGQAPSGTPTAPSHA---PAPAP--------MAATGLPPLLPAE--N 1035
Query: 486 QAMALETPT----------PGPPREGQSPASQAGTQHPPAQATAH-------------SQ 522
+A A PT PG P Q + +G + PP + S
Sbjct: 1036 KAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSV 1095
Query: 523 SSPEFKGSLASLSDSLG--------VSVMATDQDSYSTSSTEEELEQFSSPSVKKKPSMI 574
P++K + S D+L + + D + +EE E S+ +K+ +M+
Sbjct: 1096 LHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYH---KVDEEFETVSTQLLKRTQAML 1152
Score = 60.8 bits (146), Expect = 6e-09
Identities = 97/377 (25%), Positives = 137/377 (36%), Gaps = 69/377 (18%)
Query: 214 AHDANCACEIELSVGNDRLWFVNPIFIEDCSSALPTDQPPLGNCPARPLPPT--SDATSP 271
AH A+ + VG L F P+ + + +LPT P PA P T T P
Sbjct: 536 AHSAHILSAAPIQVGQPAL-FQMPVSL--AAGSLPTQSQP---APAGPAATTVLQGVTLP 589
Query: 272 TSRWAPRRPPPPPPVLPLQPCSPAQP-----PVLPALAPAPACPLPTSPPVPAPHVTPHA 326
S A P +QP +PA PVL + PAP P S P+P P A
Sbjct: 590 PSAVAMLNTPDGL----VQPATPAAATGEAAPVL-TVQPAPQAPPAVSTPLPLGLQQPQA 644
Query: 327 PGPPDHPN----QPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNL 382
PP P PP T P P+ PG ASSP + V P
Sbjct: 645 QQPPQAPTPQAAAPPQAT---TPQPS------------PGLASSPEKIVLGQP------- 682
Query: 383 PTAPPRRRVSER-----VSLEDQSPGMAAEGDQLSLPPQ--GTSDGPEDTPRESTEQGQD 435
P+A P +++ + E ++AEG LS+P ++ P P +T +
Sbjct: 683 PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKG 742
Query: 436 TEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCTQAMALET--- 492
+ P S P A Q P P K P P + L QA ++
Sbjct: 743 AGLGPQAPDSQAS-PAPAPQIPAAAPLKG----------PGPSSSPSLPHQAPLGDSPHL 791
Query: 493 PTPGPPREGQSPASQ-AGTQHPPAQATAHSQSSPEFKGSLAS---LSDSLGVSVMATDQD 548
P+P P R P S+ PP++ H P+ +L + + LGV A++
Sbjct: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851
Query: 549 SYSTSSTEEELEQFSSP 565
+ + L S P
Sbjct: 852 PTAPGPPQPPLRPQSQP 868
Score = 43.1 bits (100), Expect = 0.001
Identities = 58/217 (26%), Positives = 72/217 (33%), Gaps = 25/217 (11%)
Query: 263 PPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAP---APACP-LPTSPPV- 317
PP AT + PR PPPPPP + PP P P AP CP LP
Sbjct: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYR 1392
Query: 318 ------PAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMK-------PGAA 364
AP TP P P E L + +E + P A
Sbjct: 1393 ENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPA 1452
Query: 365 SSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQS-PGMAAEGDQLSLPPQGTSD--- 420
+S Q P A LP P +RR SE ++ S + + D L+ Q D
Sbjct: 1453 ASAAQGTGDPDWEA-PGLP--PAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSIL 1509
Query: 421 GPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPP 457
+ P + A P S P L R PP
Sbjct: 1510 NLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPP 1546
Score = 39.7 bits (91), Expect = 0.014
Identities = 74/248 (29%), Positives = 91/248 (36%), Gaps = 56/248 (22%)
Query: 279 RPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPM 338
+PPPPP L + A+PP P P PP + T P PP P + P+
Sbjct: 1332 QPPPPPATLKV-----AEPPPRPP---------PPPPPTGQMNGTVDHP-PPAAPERKPL 1376
Query: 339 MT---CERLPCPTAGLGPLREEAMKPGA-----ASSPLQQVPAPPLPAKKNLPTAPPRRR 390
T C RLP RE PGA A PA PLPAK + T+ R
Sbjct: 1377 GTAPHCPRLPLRKT----YRENVGGPGAPEGTPAGRARGGSPA-PLPAKVDEATSGLIRE 1431
Query: 391 VSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQ-DTEVKASDPHSMPEL 449
+AA D+L Q GP P S QG D + +A P P
Sbjct: 1432 -------------LAAVEDELY---QRMLKGPPPEPAASAAQGTGDPDWEA--PGLPPAK 1473
Query: 450 PRTAKQPPVPPPRKKRISRQLASTLPAPLENA---ELCTQAMALETPTPGPPREGQSPAS 506
R ++ P V S Q TL L++A L Q TP P P A+
Sbjct: 1474 RRKSESPDVDQASFSSDSPQ-DDTLTEHLQSAIDSILNLQQAPGRTPAPSYPH-----AA 1527
Query: 507 QAGTQHPP 514
AGT P
Sbjct: 1528 SAGTPASP 1535
Score = 30.4 bits (67), Expect = 8.5
Identities = 40/137 (29%), Positives = 51/137 (37%), Gaps = 15/137 (10%)
Query: 293 SPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQP---PMMTCERLPCPTA 349
+P P LA AP L +SP VPAP+V H P P P + P P A
Sbjct: 315 APTGTPSGQPLAVAPG--LGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFA 372
Query: 350 GLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGD 409
G +PGA L Q P P +NL T + + V L P A + +
Sbjct: 373 PAGATLTIQGEPGA----LPQQPKAP----QNL-TFMAAGKAGQNVVLSG-FPAPALQAN 422
Query: 410 QLSLPPQGTSDGPEDTP 426
PP T+ P
Sbjct: 423 VFKQPPATTTGAAPPQP 439
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 71.2 bits (173), Expect = 4e-12
Identities = 97/368 (26%), Positives = 132/368 (35%), Gaps = 64/368 (17%)
Query: 246 ALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPP-----PPPVLPLQPCSPA-QPPV 299
ALP PP P P PP + PTS P PP PPPVLP S A PPV
Sbjct: 550 ALPATVPP----PGMP-PPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPV 604
Query: 300 LP-----ALAPAPACPL-PTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGP 353
LP + AP P PL P S P P + P PG P PP +T +P ++
Sbjct: 605 LPPPSLSSTAPPPVMPLPPLSSATPPPGIPP--PGVPQ--GIPPQLTAAPVPPASSSQSS 660
Query: 354 LREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLE---------DQSPGM 404
E +P +P+ APP L +A P +V+ + L G+
Sbjct: 661 QVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL 720
Query: 405 AAEGDQLSLPPQGTSDGP-------EDTPRESTEQGQ-----DTEVKASDPHSMPELPR- 451
S P D P D PR S + D + D S E PR
Sbjct: 721 GESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRP 780
Query: 452 -----TAKQPPVPPPRKK----RISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQ 502
+P P PR + ++ +P + T + +L GP +G
Sbjct: 781 KGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGP 840
Query: 503 SPA-SQAGTQHPPAQ-----------ATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSY 550
PA Q Q P +Q A S FK A+ S + V + Q +
Sbjct: 841 KPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNE 900
Query: 551 STSSTEEE 558
+ S +++E
Sbjct: 901 NLSDSQQE 908
Score = 70.5 bits (171), Expect = 7e-12
Identities = 77/271 (28%), Positives = 96/271 (35%), Gaps = 40/271 (14%)
Query: 271 PTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPP 330
P S+ P P PPPVLP P PP LPA P P P P PP V P
Sbjct: 522 PYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPP------ 575
Query: 331 DHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRR 390
P PP ++ +AG P+ + P + SS P P LP TAPP
Sbjct: 576 --PGMPPSLS-------SAGPPPV----LPPPSLSS---AGPPPVLPPPSLSSTAPPPVM 619
Query: 391 VSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELP 450
+S PG+ G +PPQ T+ P S+ Q K P +P
Sbjct: 620 PLPPLSSATPPPGIPPPGVPQGIPPQLTA---APVPPASSSQSSQVPEKPR-PALLPTPV 675
Query: 451 RTAKQPPV---PPPRKKRISRQLASTLPAPLENAEL------CTQAMALETPTPGPPREG 501
PP PP + S Q+ S APL + L Q + + P P
Sbjct: 676 SFGSAPPTTYHPPLQSAGPSEQVNS--KAPLSKSALPYSSFSSDQGLGESSAAPSQPITA 733
Query: 502 --QSPASQAG-TQHPPAQATAHSQSSPEFKG 529
P G PP + S P F G
Sbjct: 734 VKDMPVRSGGLLPDPPRSSYLESPRGPRFDG 764
Score = 65.5 bits (158), Expect = 2e-10
Identities = 79/277 (28%), Positives = 107/277 (38%), Gaps = 35/277 (12%)
Query: 247 LPTDQPPL--GNCPARPLPPTSDATSPTSRWAPRRPPPP-PPVLPLQPCSPAQPPVLPAL 303
LPT PP+ + P +PP AT P P PPP PP LP P PP L +
Sbjct: 530 LPTMPPPVLPPSLPPPVMPPALPATVPP----PGMPPPVMPPSLPTSVPPPGMPPSLSSA 585
Query: 304 APAPACPLPT-----SPPV-PAPHVTPHAPGPPDHPNQPPMMTC---ERLPCP--TAGLG 352
P P P P+ PPV P P ++ AP PP P PP+ + +P P G+
Sbjct: 586 GPPPVLPPPSLSSAGPPPVLPPPSLSSTAP-PPVMP-LPPLSSATPPPGIPPPGVPQGIP 643
Query: 353 PLREEAMKPGAASSPLQQVPAPPLPAKKNLP----TAPPRRRVSERVSLEDQSPGMAAEG 408
P A P A+SS QVP P PA P +APP + L+ P
Sbjct: 644 PQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPP---TTYHPPLQSAGPSEQVN- 699
Query: 409 DQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISR 468
S P S P + G+ + + ++ ++P + PPR +
Sbjct: 700 ---SKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLES 756
Query: 469 QLASTLPAPLENAELCTQAMALETPTP-GPPREGQSP 504
P +L ++ E P P GP EG P
Sbjct: 757 PRGPRFDGPRRFEDLGSRC---EGPRPKGPRFEGNRP 790
Score = 55.8 bits (133), Expect = 2e-07
Identities = 65/265 (24%), Positives = 96/265 (36%), Gaps = 31/265 (11%)
Query: 263 PPTSDATSPTSRWAPRR---PPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPA 319
PP S P S P + PPP PP P S P LP PA P P+ P
Sbjct: 146 PPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTS--SQPYLP-----PAQPSPSQSPPSQ 198
Query: 320 PHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAK 379
++ P + ++ + P++ P R P S Q + PP
Sbjct: 199 SYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSR-----PSQGHSKSQLLAPPP---- 249
Query: 380 KNLPTAPPRRRVS-ERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEV 438
P+APP + + ++ LE + + E Q + P D TP+E + +
Sbjct: 250 ---PSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEP----DPSTMTPQEQQQYWYRQHL 302
Query: 439 KASDPHSMPELPRTAKQPPV----PPPRKKRISRQLASTLPAPLENAELCTQAMALETPT 494
+ + LP K P V P P K+ ++ S +P + E E P
Sbjct: 303 LSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPP 362
Query: 495 PGPPREGQSPASQAGTQHPPAQATA 519
P PP E QS + + QA A
Sbjct: 363 PLPPEEPQSEDPEEDARLKQLQAAA 387
Score = 43.9 bits (102), Expect = 7e-04
Identities = 41/138 (29%), Positives = 51/138 (36%), Gaps = 16/138 (11%)
Query: 262 LPPTSDATSPTSRWAPRRPPP----PPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPV 317
LPP TS PPP PPP + P S +P PA + P T PPV
Sbjct: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPV----TRPPV 1544
Query: 318 PAPHVTPHAPGPPDHPNQPPMMTC---ERLPCPT-AGLGPLREEAMKPGAASSPLQQVPA 373
P P P P PP P P + ER + GL +E S +P+
Sbjct: 1545 PIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPS 1604
Query: 374 ----PPLPAKKNLPTAPP 387
PP P ++P P
Sbjct: 1605 APVLPPPPVHSSIPPPGP 1622
Score = 42.0 bits (97), Expect = 0.003
Identities = 78/351 (22%), Positives = 111/351 (31%), Gaps = 83/351 (23%)
Query: 282 PPPPVLPLQPCSPAQPPV-LPALAPAPACPLPTSPPVPA--------------------- 319
PPPPV P PPV LP +P P T+P P+
Sbjct: 15 PPPPV-------PPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQM 67
Query: 320 ----------PHVTPHAPGPPD-----------HPNQPPMMTCERLPCPTAGLGPLREEA 358
PH P P PP P PPM P P L +++
Sbjct: 68 HQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMP-----PPPGPALSYQKQQQ 122
Query: 359 MK-----------PGAASSPLQQVP-APPLPAKKNLPTA-----PPRRRVSERVSLEDQS 401
K PG L+ P +PP+P +P + PP+ S Q
Sbjct: 123 YKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQP 182
Query: 402 PGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPP 461
A+ PP + P TP S+ + HS LP + P P
Sbjct: 183 YLPPAQPSPSQSPPSQSYLAP--TPSYSSSSSSSQSYLS---HSQSYLPSSQASPSRPSQ 237
Query: 462 RKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHS 521
+ S+ LA P+ + Q LE+ E Q QA + P+ T
Sbjct: 238 GHSK-SQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQ----QAAPEPDPSTMTPQE 292
Query: 522 QSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEEL-EQFSSPSVKKKP 571
Q ++ L SL V + + T E + E+ + P+ + P
Sbjct: 293 QQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVP 343
Score = 37.7 bits (86), Expect = 0.053
Identities = 33/117 (28%), Positives = 44/117 (37%), Gaps = 32/117 (27%)
Query: 252 PPLGNCPA---RPLPPTSDATSPTSRW-APRRPPPPPPVLPLQPCSPAQPPVLPALA--- 304
PP+G P RP P + ++ P +R P PPPPPP PL P P P A+
Sbjct: 1516 PPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP--PLPPPPPVIKPQTSAVEQER 1573
Query: 305 ----------------------PAPACPLPTSPPVPAPHVTPHAPGPPDHP-NQPPM 338
+ +P++P +P P V P P P PPM
Sbjct: 1574 WDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPM 1630
Score = 32.3 bits (72), Expect = 2.2
Identities = 27/80 (33%), Positives = 32/80 (40%), Gaps = 11/80 (13%)
Query: 244 SSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPAL 303
+S+ P PP G+ RP PP P S P PP V +P P PP P
Sbjct: 1499 TSSRPGMYPPPGSY--RPPPPMGKP--PGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP- 1553
Query: 304 APAPACPLPTSPPVPAPHVT 323
PLP PPV P +
Sbjct: 1554 ------PLPPPPPVIKPQTS 1567
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 70.1 bits (170), Expect = 1e-11
Identities = 76/287 (26%), Positives = 101/287 (35%), Gaps = 32/287 (11%)
Query: 241 EDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVL 300
ED + P L N +P S +S + R PP P SP P +
Sbjct: 508 EDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPI 567
Query: 301 PALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMK 360
P P P P P P AP PP P +P P LRE +
Sbjct: 568 TTSPPVPQEPAPVPSP-------PRAPTPPSTP----------VPLPEKRRSILREPTFR 610
Query: 361 PGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSL------- 413
+ + L P PP P P+ PP S R L ++P L +
Sbjct: 611 WTSLTRELP--PPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTP 668
Query: 414 PPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLAST 473
PP G + PE P + + + E +A + LPR A P V P K +S A
Sbjct: 669 PPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFA--PVVTTPVKAEVSPHGAPA 726
Query: 474 LP-APLENAELCTQAMALET---PTPGPPREGQSPASQAGTQHPPAQ 516
L P A+L AL+T P PP + Q + Q PP +
Sbjct: 727 LSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLE 773
Score = 67.8 bits (164), Expect = 5e-11
Identities = 76/289 (26%), Positives = 109/289 (37%), Gaps = 46/289 (15%)
Query: 271 PTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPP 330
P + + PPP PL P +P+ PP LP P+ + P P PP P P P P PP
Sbjct: 392 PAAEKEEAKLPPP----PLTPPAPSPPPPLP--PPSTSPPPPLCPPPPPPVSPPPLPSPP 445
Query: 331 DHPNQ-------PPMM--TCERLPCPTAGLGPL--REEAMKPGAASSPLQQVPAPPLPA- 378
P Q PP++ TC R G PL + A + A + P P P P+
Sbjct: 446 PPPAQEEQEESPPPVVPATCSR----KRGRPPLTPSQRAEREAARAGPEGTSPPTPTPST 501
Query: 379 -----KKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQ-LSLPPQGTSDGPEDTPRESTEQ 432
++ PT P+ + + P ++A + + P + + P P+
Sbjct: 502 ATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSP 561
Query: 433 GQDTEVKAS-----DPHSMPELPRTAKQP--PVPPPRKKRISRQLASTLPAPLENAELCT 485
+ S +P +P PR P PVP P K+R S L P T
Sbjct: 562 VLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRR------SILREPTFRWTSLT 615
Query: 486 QAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASL 534
+ + P P PP P + A + P A P+F S A L
Sbjct: 616 RELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRA-----PQFTPSEAHL 659
Score = 53.5 bits (127), Expect = 9e-07
Identities = 75/298 (25%), Positives = 103/298 (34%), Gaps = 65/298 (21%)
Query: 193 PAEPPRDRA--PGFP--LVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSSALP 248
PA+P R A PG P V SL P A + V + +F++ P
Sbjct: 2156 PADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNK-----LGQVFVKMAGEGEP 2210
Query: 249 TDQPPLGNCPARPLPPTSDATSPTSRWA-----------------PRRPPPPPPVLPLQP 291
PP P PLPPT T+PTS W P PPPPPP+ +
Sbjct: 2211 V--PPPVKQP--PLPPTISPTAPTS-WTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLS 2265
Query: 292 CSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGL 351
PA PP + SPP P P+ P + P + P G
Sbjct: 2266 SGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQV-------PGLGS 2318
Query: 352 GPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQL 411
G MK L + P PA + P L+++SP + D
Sbjct: 2319 GGFSRVRMKTPTVRGVL-DLDRPGEPAGEESPG-----------PLQERSPLLPLPEDG- 2365
Query: 412 SLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQ 469
PPQ DGP D ES E +S+ ++PP P ++ + ++
Sbjct: 2366 --PPQ-VPDGPPDLLLESQWHHYSGEASSSE-----------EEPPSPDDKENQAPKR 2409
Score = 53.1 bits (126), Expect = 1e-06
Identities = 59/235 (25%), Positives = 82/235 (34%), Gaps = 46/235 (19%)
Query: 286 VLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLP 345
++P A+ P P PAP+ P PP+P P +P PP P PP ++ LP
Sbjct: 390 MMPAAEKEEAKLPPPPLTPPAPSPP----PPLPPPST---SPPPPLCPPPPPPVSPPPLP 442
Query: 346 CPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMA 405
P P A ++ P P +PA + P S+R E G
Sbjct: 443 SP------------PPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPE 490
Query: 406 AEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMP----------ELPRTAKQ 455
P T PED+P + + T +K MP + PR
Sbjct: 491 GTSPPTPTPSTATGGPPEDSPTVAPK--STTFLKNIRQFIMPVVSARSSRVIKTPRRFMD 548
Query: 456 PPVPPPRKKRISRQL----ASTLPAPLENAELCTQAMALETPTPGPPREGQSPAS 506
P P K +S L ++ P P E A P P PPR P++
Sbjct: 549 EDPPKPPKVEVSPVLRPPITTSPPVPQEPA-----------PVPSPPRAPTPPST 592
Score = 48.1 bits (113), Expect = 4e-05
Identities = 62/259 (23%), Positives = 100/259 (38%), Gaps = 32/259 (12%)
Query: 234 FVNPIFIEDCSSALPTDQPPLGNCPARP----LPPTSDATSPTSRWAPRRPPPPPPVLPL 289
F+ P+ S + T + + P +P + P TS P+ P P P P
Sbjct: 527 FIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSP-PR 585
Query: 290 QPCSPAQPPVLP----ALAPAPAC-------PLPTSPPVPAPHVTPHAPGPPDHPNQPPM 338
P P+ P LP ++ P LP PP P P P P P ++ P+
Sbjct: 586 APTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPL 645
Query: 339 MTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRV--SERVS 396
+ P+ + E + P +P + P P P + P P R V + +S
Sbjct: 646 LLRAPQFTPSEAHLKIYESVLTPPPLGAP--EAPEPEPPPADDSPAEPEPRAVGRTNHLS 703
Query: 397 LEDQSPGMAAEGDQLSLPPQGT---SDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTA 453
L +P + + + P G S+GP+ T + + Q + + P ++P P+
Sbjct: 704 LPRFAP-VVTTPVKAEVSPHGAPALSNGPQ-TQAQLLQPLQALQTQLL-PQALPP-PQPQ 759
Query: 454 KQPP-----VPPPRKKRIS 467
QPP +PP K RI+
Sbjct: 760 LQPPPSPQQMPPLEKARIA 778
Score = 41.6 bits (96), Expect = 0.004
Identities = 48/186 (25%), Positives = 66/186 (35%), Gaps = 35/186 (18%)
Query: 325 HAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAAS--SPLQQVPAPPLPAKKNL 382
H+P P P P PL + + PGA SP+Q + P P +
Sbjct: 1806 HSPAPSSEP-------------PGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSA 1852
Query: 383 PTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASD 442
P PR R+ + + SP P G S GP +P + D
Sbjct: 1853 PPPAPRSFSGARIKVPNYSPSRR--------PLGGVSFGPLPSPGSPSSLTHHIPT-VGD 1903
Query: 443 PHSMPELPRTAKQP----PVPPPRK-----KRISRQLASTLPAPLENAELCTQA-MALET 492
P P PR +++P P PPP + + S QL P + A T +A
Sbjct: 1904 P-DFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPG 1962
Query: 493 PTPGPP 498
P P PP
Sbjct: 1963 PAPSPP 1968
Score = 40.0 bits (92), Expect = 0.011
Identities = 73/285 (25%), Positives = 96/285 (33%), Gaps = 48/285 (16%)
Query: 261 PLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPP--VP 318
P P S A P++ PRR PP P PC Q V+ A A A P P PP VP
Sbjct: 203 PQAPRSRACEPST---PRRSRGRPPGRPAGPCRRKQQAVVVAEA-AVTIPKPEPPPPVVP 258
Query: 319 APHVT-----PHAPGP-PDHPNQPPMMTCERLPCPTAGLG---------PLREEAMKPGA 363
H T PGP P P + + G G R + +K G
Sbjct: 259 VKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQ 318
Query: 364 ASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPE 423
S L+ + P+RRV S + SP + +L D E
Sbjct: 319 LSLGLESGQGQGQHEESWQDV--PQRRVG---SGQGGSPCWKKQEQKL--------DDEE 365
Query: 424 DTPRESTE---QGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLEN 480
+ +E E +G++ E +A MP + + P PP T PAP
Sbjct: 366 EEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPP-----------LTPPAPSPP 414
Query: 481 AELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSP 525
L + + P PP SP PPAQ P
Sbjct: 415 PPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPP 459
Score = 39.3 bits (90), Expect = 0.018
Identities = 75/317 (23%), Positives = 105/317 (33%), Gaps = 49/317 (15%)
Query: 245 SALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPP-----PVLPLQPCSPAQPP- 298
S+L P +G+ P P PP + R +P P PPP P L P PP
Sbjct: 1892 SSLTHHIPTVGD-PDFPAPPRR-----SRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPT 1945
Query: 299 -VLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTA----GLGP 353
V+ AL P +PP PAP P PD + + A G P
Sbjct: 1946 SVVTALTPTSG---ELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEP 2002
Query: 354 LREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSL 413
+EE + GA S + P + + P R +PG+A
Sbjct: 2003 FQEEIVAAGAMGS------SHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLA-------- 2048
Query: 414 PPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLAST 473
P T P + + G D+E +A + PR PP P + A
Sbjct: 2049 -PSATPGAPRIEQLDGVDDGTDSEAEA------VQQPRGQGTPPSGPGVVRAGVLGAAGD 2101
Query: 474 LPAPLENAELCTQAMALET------PTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEF 527
P E+ L+ GP E PA P+Q S + P
Sbjct: 2102 RARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADP-- 2159
Query: 528 KGSLASLSDSLGVSVMA 544
+ A L + GV V++
Sbjct: 2160 TRTFAWLPGAPGVRVLS 2176
Score = 37.7 bits (86), Expect = 0.053
Identities = 67/285 (23%), Positives = 98/285 (34%), Gaps = 33/285 (11%)
Query: 193 PAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSSALPTDQP 252
P PP P P SS RP A E + P A + P
Sbjct: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPL--GAPEAPEPEPP 682
Query: 253 PLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLP 312
P + PA P P T+ S P PV+ + P PAL+ P
Sbjct: 683 PADDSPAEPEPRAVGRTNHLSL------PRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQ 736
Query: 313 TSPPVPA--PHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQ 370
P+ A + P A PP QPP P+ P E+A G S PL
Sbjct: 737 LLQPLQALQTQLLPQALPPPQPQLQPP---------PSPQQMPPLEKARIAGVGSLPLSG 787
Query: 371 VPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPREST 430
V ++ + + R +V + Q +AA + L P G + ++ +
Sbjct: 788 V-------EEKMFSLLKRAKVQLFKIDQQQQQKVAA---SMPLSPGGQMEEVAGAVKQIS 837
Query: 431 EQGQDTEVKASDPHSMPELPR-TAKQPPVPPPRKKRISRQLASTL 474
++G V++ D + R + + PV PR K + R A L
Sbjct: 838 DRG---PVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVAL 879
Score = 37.0 bits (84), Expect = 0.091
Identities = 40/127 (31%), Positives = 50/127 (39%), Gaps = 9/127 (7%)
Query: 248 PTDQPPLGNCPARPLPPTSDATSPTSRWAP-RRPPPPPPVLPLQPCSPAQPPVLPALAPA 306
P +P G+ P S A ++P RRP PL SP P L P
Sbjct: 1843 PPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLP--SPGSPSSLTHHIPT 1900
Query: 307 PACPLPTSPPVPAPHVTPHAP-GPPDHPNQPPMMTCE--RLPCPTA---GLGPLREEAMK 360
P +PP + +P AP PP PP+ T R+P PT+ L P E
Sbjct: 1901 VGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAP 1960
Query: 361 PGAASSP 367
PG A SP
Sbjct: 1961 PGPAPSP 1967
Score = 30.4 bits (67), Expect = 8.5
Identities = 65/287 (22%), Positives = 94/287 (32%), Gaps = 47/287 (16%)
Query: 254 LGNCPARPLPPTSDATSPTSRW-------------APRRPPPPPPVLPLQPCSPAQPPVL 300
+G+ P + + +SPTSR+ AP P P + L
Sbjct: 2013 MGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEA 2072
Query: 301 PALA-PAPACPLPTSPPVPAPHVT----PHAPGPPDHPNQPPMMTCERLPCPTAGLGPLR 355
A+ P P+ P V V A P D P++ + L P G R
Sbjct: 2073 EAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPR 2132
Query: 356 EEAMKPGA----ASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQL 411
EE++ P S P Q + A P + P +PG+ L
Sbjct: 2133 EESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPG-------------APGVRV----L 2175
Query: 412 SLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLA 471
SL P P + + VK + +P KQPP+PP + +
Sbjct: 2176 SLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGE--PVPPPVKQPPLPPTISP--TAPTS 2231
Query: 472 STLP-APLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQA 517
TLP PL + + P P PP + +G PP QA
Sbjct: 2232 WTLPPGPLLGV---LPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQA 2275
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 68.9 bits (167), Expect = 2e-11
Identities = 79/292 (27%), Positives = 106/292 (36%), Gaps = 40/292 (13%)
Query: 248 PTDQPPLGNCPARPLPPTSDATSPTSRWAPR-----RPPPPPPVLPLQPCSPAQP----P 298
P+ LG P+ P TS SPT P RP P P P + + P P
Sbjct: 1071 PSSSSGLGTSPSSS-PRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
Query: 299 VLPALAPAPACPL-PTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPT----AGLGP 353
P PA PL P PP P P P P PP P P + R P PT G+G
Sbjct: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP---SGARSPAPTRKEFGGIGA 1186
Query: 354 LREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSL 413
PG A ++ +P K N+ + P S + L P +
Sbjct: 1187 ----PPSPGVARREMEAPKSPGTTRKDNIGRSQP----SPQAGLAGPGPAGYSTARPTIP 1238
Query: 414 PPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPP-VPPPRKKRISRQLAS 472
P G P+ R S G+ T P S + T+K +P P K + + S
Sbjct: 1239 PRAGVISAPQSHARASA--GRLT------PESQSKTSETSKGSTFLPEPLKPQAAFPPQS 1290
Query: 473 TLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSS 524
+LP P + + +A P GP P + Q PP ++HS S
Sbjct: 1291 SLPPPAQRLQEPLVPVAAPMPQSGP-----QPNLETPPQPPPRSRSSHSLPS 1337
Score = 55.5 bits (132), Expect = 2e-07
Identities = 89/392 (22%), Positives = 140/392 (35%), Gaps = 82/392 (20%)
Query: 253 PLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPA---- 308
P+ PA PLP P P+RPPPP PV P +P Q P P+ A +PA
Sbjct: 1124 PIDAQPATPLPQKD----PAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRK 1179
Query: 309 ----CPLPTSPPV-----------------------PAPHVTPHAPGPPDH----PNQPP 337
P SP V P+P PGP + P PP
Sbjct: 1180 EFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPP 1239
Query: 338 MM------------------------TCERLPCPTAGLGPLREEAMKPGAAS--SPLQQV 371
T E T PL+ +A P +S P Q++
Sbjct: 1240 RAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL 1299
Query: 372 PAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTE 431
P +P +P + P+ + +S + + S PQ ++G D RES
Sbjct: 1300 QEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPL 1359
Query: 432 QGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCTQAMALE 491
+ E + + ++ + + + PVP P KR+ QL S + + ++ C M
Sbjct: 1360 KIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLI-QLPSATQSNVLSSVSCMPTM--- 1415
Query: 492 TPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSYS 551
PP +S + + P T ++++P + + + G A ++S +
Sbjct: 1416 -----PPIPARSQSQENMRSSPNPFITGLTRTNP-----FSDRTAAPGNPFRAKSEESEA 1465
Query: 552 TSSTEEELEQFSSPSVKKKPSMILGKARHRLS 583
TS +E SP +P LG + R S
Sbjct: 1466 TSWFSKEEPVTISPFPSLQP---LGHNKSRAS 1494
Score = 53.1 bits (126), Expect = 1e-06
Identities = 90/393 (22%), Positives = 123/393 (31%), Gaps = 102/393 (25%)
Query: 244 SSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPC--------SPA 295
++ LP P P RP PP A PT P+RPPPP P +P
Sbjct: 1130 ATPLPQKDPAQPLEPKRPPPPRPVA-PPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPP 1188
Query: 296 QPPVLPALAPAPACPLPT-----SPPVPAPHVTPHAPGPPDH----PNQPPMMTCERLP- 345
P V AP P T P+P PGP + P PP P
Sbjct: 1189 SPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQ 1248
Query: 346 -CPTAGLGPLREEA-----------------MKPGAASSPLQQVPAP------------- 374
A G L E+ +KP AA P +P P
Sbjct: 1249 SHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAA 1308
Query: 375 ------PLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTP-- 426
P P + P PPR R S + E S Q + G SDG ++P
Sbjct: 1309 PMPQSGPQPNLETPPQPPPRSRSSHSLPSEASS--------QPQVKTNGISDGKRESPLK 1360
Query: 427 --------------RESTEQGQDTEVKASDPHSMPELPRTAK---------QPPVPPPRK 463
++ Q + V DP + +LP + P +PP
Sbjct: 1361 IDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPA 1420
Query: 464 KRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAG-----------TQH 512
+ S++ + P P T + T PG P +S S+A +
Sbjct: 1421 RSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPF 1480
Query: 513 PPAQATAHSQSSPEFKGSLASLSDSLGVSVMAT 545
P Q H++S SL DS + +T
Sbjct: 1481 PSLQPLGHNKS--RASSSLDGFKDSFDLQGQST 1511
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 68.9 bits (167), Expect = 2e-11
Identities = 79/292 (27%), Positives = 106/292 (36%), Gaps = 40/292 (13%)
Query: 248 PTDQPPLGNCPARPLPPTSDATSPTSRWAPR-----RPPPPPPVLPLQPCSPAQP----P 298
P+ LG P+ P TS SPT P RP P P P + + P P
Sbjct: 1071 PSSSSGLGTSPSSS-PRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
Query: 299 VLPALAPAPACPL-PTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPT----AGLGP 353
P PA PL P PP P P P P PP P P + R P PT G+G
Sbjct: 1130 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP---SGARSPAPTRKEFGGIGA 1186
Query: 354 LREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSL 413
PG A ++ +P K N+ + P S + L P +
Sbjct: 1187 ----PPSPGVARREMEAPKSPGTTRKDNIGRSQP----SPQAGLAGPGPAGYSTARPTIP 1238
Query: 414 PPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPP-VPPPRKKRISRQLAS 472
P G P+ R S G+ T P S + T+K +P P K + + S
Sbjct: 1239 PRAGVISAPQSHARASA--GRLT------PESQSKTSETSKGSTFLPEPLKPQAAFPPQS 1290
Query: 473 TLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSS 524
+LP P + + +A P GP P + Q PP ++HS S
Sbjct: 1291 SLPPPAQRLQEPLVPVAAPMPQSGP-----QPNLETPPQPPPRSRSSHSLPS 1337
Score = 44.3 bits (103), Expect = 6e-04
Identities = 61/234 (26%), Positives = 80/234 (34%), Gaps = 46/234 (19%)
Query: 244 SSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPAL 303
++ LP P P RP PP A PT P+RPPPP S A+ P P
Sbjct: 1130 ATPLPQKDPAQPLEPKRPPPPRPVA-PPTRPAPPQRPPPP---------SGARSPA-PTR 1178
Query: 304 APAPACPLPTSPPVPAPHV-TPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPG 362
P SP V + P +PG N P P AGL PG
Sbjct: 1179 KEFGGIGAPPSPGVARREMEAPKSPGTTRKDN-----IGRSQPSPQAGLA-------GPG 1226
Query: 363 AASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGD------------Q 410
A P +P + + +AP + L +S +E Q
Sbjct: 1227 PAG---YSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQ 1283
Query: 411 LSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKK 464
+ PPQ + P +E V A P S P+ + PP PPPR +
Sbjct: 1284 AAFPPQSSLPPPAQRLQEPL-----VPVAAPMPQSGPQ--PNLETPPQPPPRSR 1330
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 68.6 bits (166), Expect = 3e-11
Identities = 60/199 (30%), Positives = 69/199 (34%), Gaps = 18/199 (9%)
Query: 277 PRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQP 336
P PP PP P P P QPP LP L P P P S P PH HA GP P
Sbjct: 1277 PAPPPYLPPQQPSLPPPPQQPPPLPQLGSIP--PPPASAPPVGPHRHFHAHGPVPGPQHY 1334
Query: 337 PMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVS 396
+ R P AG P PL Q P PLP P PP + +
Sbjct: 1335 TLGRPGRAPRRGAGGHP-----QFAPHGRHPLHQ-PTSPLPLYSPAPQHPPAHKQGPKHF 1388
Query: 397 LEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQP 456
+ P M +P G + GP P + PHS +P P
Sbjct: 1389 IFSHHPQM--------MPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHS--PIPPHPSYP 1438
Query: 457 PVPPPRKKRISRQLASTLP 475
P+PPP L T P
Sbjct: 1439 PLPPPSPHTPHSPLPPTSP 1457
Score = 40.8 bits (94), Expect = 0.006
Identities = 33/83 (39%), Positives = 36/83 (43%), Gaps = 14/83 (16%)
Query: 262 LPPTSDATSPTSRWAPRRPP------PPPPVLPLQPCSPAQP-PVLPALAPAPACPLPTS 314
+P A P SR PP P P PL P SP P P P L P P+ P S
Sbjct: 1397 MPAAGAAGGPGSR-----PPGGSYSHPHHPQSPLSPHSPIPPHPSYPPL-PPPSPHTPHS 1450
Query: 315 P-PVPAPHVTPHAPGPPDHPNQP 336
P P +PH HA GPP N P
Sbjct: 1451 PLPPTSPHGPLHASGPPGTANPP 1473
Score = 32.0 bits (71), Expect = 2.9
Identities = 37/135 (27%), Positives = 49/135 (36%), Gaps = 17/135 (12%)
Query: 386 PPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHS 445
P ++ +R S E Q A L L T P++S E+ TE P
Sbjct: 491 PGSAQLEKRESKEQQEDSSATSFSDLPLYLDDT------VPQQSPERLPSTE---PPPQG 541
Query: 446 MPELPRTAKQPPVPPP-----RKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPRE 500
PE A PPVPPP R+ + P LE + +A L T PP +
Sbjct: 542 RPEFWAPAPLPPVPPPVPSGTREDGSREEGTRRGPGCLECRDFRLRAAHLPLLTIEPPSD 601
Query: 501 GQ---SPASQAGTQH 512
S S G+ H
Sbjct: 602 SSVDLSDRSDRGSVH 616
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 68.2 bits (165), Expect = 4e-11
Identities = 107/419 (25%), Positives = 147/419 (35%), Gaps = 58/419 (13%)
Query: 191 GKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSSALPTD 250
G PA PP P S RP + + E E VG+ L + SAL
Sbjct: 701 GPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGST-LGSYATLTRRPGRSALVRT 759
Query: 251 QPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACP 310
P + PAR P + R P PPPP + + SP PP+ + P
Sbjct: 760 SPSVTPTPARGTPRSQSFALRARRKGPP-PPPPKRLSSVSGPSPEPPPLDESPGPKEGAT 818
Query: 311 LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCP--------TAGLG-PLREEA--- 358
P + P PGPP P P T E P P ++G G P EE
Sbjct: 819 GPRRRTLSEPAGPSEPPGPP-APAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLT 877
Query: 359 --MKPGAASSPLQQVPAPP-----LPAKKNLPTAPP-RRRVSERVSLEDQSPGMAAEGDQ 410
+P A P ++ P PP L + P R R + +L A G
Sbjct: 878 IKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPA 937
Query: 411 LSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQL 470
LP + P P S Q + + + A + P P A QPPVPP +
Sbjct: 938 APLPSPTPGESP---PASSLPQPEPSSLPAQGVPT-PLAPSPAMQPPVPPCPGPGLESSA 993
Query: 471 AS----------------------TLPAPLENAELCTQAMALETPTPGP---PREGQSPA 505
AS T P P+ A CTQ +A P P PR P
Sbjct: 994 ASRWNGETEPPAAPAALLKVPGAGTAPKPVSVA--CTQ-LAFSGPKLAPRLGPRPVPPPR 1050
Query: 506 SQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSS 564
++ P QA Q + SLA+ + S+ +Q+ ++ST+ L+ S+
Sbjct: 1051 PESTGTVGPGQA---QQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDIST 1106
Score = 54.7 bits (130), Expect = 4e-07
Identities = 79/341 (23%), Positives = 107/341 (31%), Gaps = 81/341 (23%)
Query: 261 PLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAP 320
P P D + P R P PP + P P V +P+ P P PP AP
Sbjct: 635 PQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAP-GPPPGAP 693
Query: 321 HVTPHAPGPPDHPNQPPMMTCE----RLPCPTAG-------------LGPLREEAMKPG- 362
+ GPP P PP P PT G LG +PG
Sbjct: 694 WAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGR 753
Query: 363 --------------AASSPLQQV---------PAPPLPAKKNLPTAP------------- 386
A +P Q P PP P + + + P
Sbjct: 754 SALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGP 813
Query: 387 ------PRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKA 440
PRRR + + PG A S + GPE TP G+
Sbjct: 814 KEGATGPRRRTLSEPAGPSEPPGPPAPAGPAS-DTEEEEPGPEGTPPSRGSSGEGLPFAE 872
Query: 441 SDPHSMPELPRTAKQP----PVPP------PRKKRISRQLASTLPAPLENAELCTQAMAL 490
++ + P+ A P PVPP + R+ PL+ A L A +
Sbjct: 873 EGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALL---AFGV 929
Query: 491 ETPTPGP------PREGQSPASQAGTQHPPAQATAHSQSSP 525
+ TPGP P G+SP + + Q P+ A +P
Sbjct: 930 ASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTP 970
Score = 51.2 bits (121), Expect = 5e-06
Identities = 78/275 (28%), Positives = 97/275 (35%), Gaps = 54/275 (19%)
Query: 284 PPVLPLQPC-SPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQP-----P 337
P LPL P SP+Q + A + S PAP + P PP N P P
Sbjct: 603 PEPLPLPPARSPSQESI-----GARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERP 657
Query: 338 MMTCERLPCPTAGLGPLREEAMKP-GAASSPLQQVPAPPLPAK------KNLPTAPPRRR 390
C LP G GP M P G+ SSP P PP A P PP
Sbjct: 658 PKLCSSLP----GQGPPPYVFMYPQGSPSSP---APGPPPGAPWAFSYLAGPPATPPDPP 710
Query: 391 VSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRES-----TEQGQDTEVKAS---- 441
+R S PG EGD +G ++GP + S G+ V+ S
Sbjct: 711 RPKRRSHSLSRPG-PTEGD-----AEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVT 764
Query: 442 ------DPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENA----ELCTQAMALE 491
P S R ++ P PPP K+ S S P PL+ + E T
Sbjct: 765 PTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRT 824
Query: 492 TPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPE 526
P P E P + AG PA T + PE
Sbjct: 825 LSEPAGPSEPPGPPAPAG----PASDTEEEEPGPE 855
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 68.2 bits (165), Expect = 4e-11
Identities = 107/419 (25%), Positives = 147/419 (35%), Gaps = 58/419 (13%)
Query: 191 GKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSSALPTD 250
G PA PP P S RP + + E E VG+ L + SAL
Sbjct: 783 GPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGST-LGSYATLTRRPGRSALVRT 841
Query: 251 QPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACP 310
P + PAR P + R P PPPP + + SP PP+ + P
Sbjct: 842 SPSVTPTPARGTPRSQSFALRARRKGPP-PPPPKRLSSVSGPSPEPPPLDESPGPKEGAT 900
Query: 311 LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCP--------TAGLG-PLREEA--- 358
P + P PGPP P P T E P P ++G G P EE
Sbjct: 901 GPRRRTLSEPAGPSEPPGPP-APAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLT 959
Query: 359 --MKPGAASSPLQQVPAPP-----LPAKKNLPTAPP-RRRVSERVSLEDQSPGMAAEGDQ 410
+P A P ++ P PP L + P R R + +L A G
Sbjct: 960 IKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPA 1019
Query: 411 LSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQL 470
LP + P P S Q + + + A + P P A QPPVPP +
Sbjct: 1020 APLPSPTPGESP---PASSLPQPEPSSLPAQGVPT-PLAPSPAMQPPVPPCPGPGLESSA 1075
Query: 471 AS----------------------TLPAPLENAELCTQAMALETPTPGP---PREGQSPA 505
AS T P P+ A CTQ +A P P PR P
Sbjct: 1076 ASRWNGETEPPAAPAALLKVPGAGTAPKPVSVA--CTQ-LAFSGPKLAPRLGPRPVPPPR 1132
Query: 506 SQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSS 564
++ P QA Q + SLA+ + S+ +Q+ ++ST+ L+ S+
Sbjct: 1133 PESTGTVGPGQA---QQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDIST 1188
Score = 54.7 bits (130), Expect = 4e-07
Identities = 79/341 (23%), Positives = 107/341 (31%), Gaps = 81/341 (23%)
Query: 261 PLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAP 320
P P D + P R P PP + P P V +P+ P P PP AP
Sbjct: 717 PQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAP-GPPPGAP 775
Query: 321 HVTPHAPGPPDHPNQPPMMTCE----RLPCPTAG-------------LGPLREEAMKPG- 362
+ GPP P PP P PT G LG +PG
Sbjct: 776 WAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGR 835
Query: 363 --------------AASSPLQQV---------PAPPLPAKKNLPTAP------------- 386
A +P Q P PP P + + + P
Sbjct: 836 SALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGP 895
Query: 387 ------PRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKA 440
PRRR + + PG A S + GPE TP G+
Sbjct: 896 KEGATGPRRRTLSEPAGPSEPPGPPAPAGPAS-DTEEEEPGPEGTPPSRGSSGEGLPFAE 954
Query: 441 SDPHSMPELPRTAKQP----PVPP------PRKKRISRQLASTLPAPLENAELCTQAMAL 490
++ + P+ A P PVPP + R+ PL+ A L A +
Sbjct: 955 EGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALL---AFGV 1011
Query: 491 ETPTPGP------PREGQSPASQAGTQHPPAQATAHSQSSP 525
+ TPGP P G+SP + + Q P+ A +P
Sbjct: 1012 ASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTP 1052
Score = 51.2 bits (121), Expect = 5e-06
Identities = 78/275 (28%), Positives = 97/275 (35%), Gaps = 54/275 (19%)
Query: 284 PPVLPLQPC-SPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQP-----P 337
P LPL P SP+Q + A + S PAP + P PP N P P
Sbjct: 685 PEPLPLPPARSPSQESI-----GARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERP 739
Query: 338 MMTCERLPCPTAGLGPLREEAMKP-GAASSPLQQVPAPPLPAK------KNLPTAPPRRR 390
C LP G GP M P G+ SSP P PP A P PP
Sbjct: 740 PKLCSSLP----GQGPPPYVFMYPQGSPSSP---APGPPPGAPWAFSYLAGPPATPPDPP 792
Query: 391 VSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRES-----TEQGQDTEVKAS---- 441
+R S PG EGD +G ++GP + S G+ V+ S
Sbjct: 793 RPKRRSHSLSRPG-PTEGD-----AEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVT 846
Query: 442 ------DPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENA----ELCTQAMALE 491
P S R ++ P PPP K+ S S P PL+ + E T
Sbjct: 847 PTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRT 906
Query: 492 TPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPE 526
P P E P + AG PA T + PE
Sbjct: 907 LSEPAGPSEPPGPPAPAG----PASDTEEEEPGPE 937
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 67.8 bits (164), Expect = 5e-11
Identities = 70/302 (23%), Positives = 96/302 (31%), Gaps = 42/302 (13%)
Query: 249 TDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPA 308
T PP P+ P+ T+ T+ P P PP P P + P P P+P
Sbjct: 1445 TTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP-PTTTPSPP 1503
Query: 309 CPLPTSPP----------VPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEA 358
P +PP P+P T PP PP T P T L P +
Sbjct: 1504 TTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1563
Query: 359 MKPGAASS-PLQQVPAPPLPAKKNLPT------------APPRRRVSERVSLEDQSP--- 402
P ++ P P+PP + PT +PP + SP
Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTT 1623
Query: 403 -GMAAEGDQLSLPPQGTSDGP---EDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPV 458
+ +LPP T P TP +T T S P + P P
Sbjct: 1624 TPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSS 1683
Query: 459 P------PPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQH 512
P PP + + + P ++ + T T TP PP + S T
Sbjct: 1684 PITTTPSPP-----TTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS 1738
Query: 513 PP 514
PP
Sbjct: 1739 PP 1740
Score = 67.4 bits (163), Expect = 6e-11
Identities = 86/357 (24%), Positives = 115/357 (32%), Gaps = 46/357 (12%)
Query: 253 PLGNCPARPLPPTSDATSP---TSRWAPRRPP---------PPPPVLPLQPCSPAQPPVL 300
P+ C P PPT+ + P T+ P P PPP P P + P
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP- 1449
Query: 301 PALAPAPACPLPTSPP---VPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREE 357
P P+P T+PP P+P T P PP PP T P PT P
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTT--TPSPPTTTPSPP-TTTTTTPPPTTTPSPPTTT 1506
Query: 358 AMKPGAASS--PLQQVPAPP-----LPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQ 410
+ P A+++ P P+PP P P+ P ++ S P
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP---- 1562
Query: 411 LSLPPQGTSDGPEDT----PRESTEQGQDTEVKASDPHSMPELPRTAKQPPVP-----PP 461
S PP T+ P T P +T P + P P T P P PP
Sbjct: 1563 -SPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPP 1621
Query: 462 RKKRISRQLASTL--PAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATA 519
I+ ++T P + T T TP PP T PP T
Sbjct: 1622 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP 1681
Query: 520 HS----QSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKKPS 572
S SP + S + T ST++ ++PS PS
Sbjct: 1682 SSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS 1738
Score = 56.6 bits (135), Expect = 1e-07
Identities = 62/259 (23%), Positives = 82/259 (31%), Gaps = 32/259 (12%)
Query: 237 PIFIEDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPP-----PPPPVLPLQP 291
PI ++ LP P PP + SP + P P PPP P P
Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPP 1605
Query: 292 CSPAQPPVLPALAPAPACPLPTSPPVPA---PHVTPHAPGPPDHPNQPPMMTCERLPCPT 348
+ P P P+P P +PP P T +P PP PP T P T
Sbjct: 1606 TTTTTTPP-PTTTPSPPTTTPITPPTSTTTLPPTTTPSP-PPTTTTTPPPTTTPSPPTTT 1663
Query: 349 AGLGPLREEAMKPGAA--SSPLQQVPAPP-----LPAKKNLPTAPPRRRVSERVSLEDQS 401
P+ P SSP+ P+PP P+ P++P + +
Sbjct: 1664 TPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP 1723
Query: 402 PGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPP 461
P P T+ P TP T T + L T P + PP
Sbjct: 1724 P-----------PTTMTTPSPTTTPSPPT----TTMTTLPPTTTSSPLTTTPLPPSITPP 1768
Query: 462 RKKRISRQLASTLPAPLEN 480
S +T PL N
Sbjct: 1769 TFSPFSTTTPTTPCVPLCN 1787
Score = 46.2 bits (108), Expect = 2e-04
Identities = 70/319 (21%), Positives = 94/319 (29%), Gaps = 63/319 (19%)
Query: 248 PTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAP 307
PT P P P + +PT+ P P +P P+ P
Sbjct: 4104 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4163
Query: 308 A-----CPLPTSPPV-------PAPHVTPHAPGPPDHPNQPPMMTCERL-PCPTAGLGPL 354
PT+ P+ P P T GPP H + P+ P P +
Sbjct: 4164 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQT 4223
Query: 355 REEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLP 414
P S+ L P + P + P +P + G LS P
Sbjct: 4224 SRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPT------------APTTTSGGHTLS-P 4270
Query: 415 PQGTSDGPEDTPRESTEQG----------QDTEVKA----SDPHSMPELPRTAKQPPVPP 460
P T+ P TP T G Q T A P S P + RT P
Sbjct: 4271 PPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPY-- 4328
Query: 461 PRKKRISRQLASTLPAPLENA-----------ELCTQAMALE----------TPTPGPPR 499
P I L T AP E C+ + LE +PTP P +
Sbjct: 4329 PSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSK 4388
Query: 500 EGQSPASQAGTQHPPAQAT 518
+P+ + T P T
Sbjct: 4389 STPTPSKPSSTPSKPTPGT 4407
Score = 42.4 bits (98), Expect = 0.002
Identities = 65/302 (21%), Positives = 86/302 (28%), Gaps = 28/302 (9%)
Query: 248 PTDQPPLGNCPARPLP-PTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPA 306
PT P P P PT T T+ P P P P P
Sbjct: 4012 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQTPTTTPITTTT 4067
Query: 307 PACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCP---TAGLGPLREEAMKPGA 363
P PT P TP P P T P T + P
Sbjct: 4068 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4127
Query: 364 ASSPLQQ---VPAPPLPAKKNLPTAPPRRRVSERVSLED----QSPGMAAEGDQLSLPPQ 416
++P+ V P P PT P + Q+P ++ P
Sbjct: 4128 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4187
Query: 417 GTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVP-----------PPRKKR 465
T G + P T E+ S+P P+T++ P PP +
Sbjct: 4188 PTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 4247
Query: 466 ISRQLASTLPAPLENAELCTQAMALETPT--PGPPREGQSPASQAGTQHPPAQATAHSQS 523
S ST AP + T + T T PG P G + S + Q T S
Sbjct: 4248 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAW 4307
Query: 524 SP 525
+P
Sbjct: 4308 TP 4309
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 67.0 bits (162), Expect = 8e-11
Identities = 83/292 (28%), Positives = 108/292 (36%), Gaps = 64/292 (21%)
Query: 247 LPTDQPPLGNCP-----ARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLP 301
+P P LGN AR PP + AP P PPPP PL P P+ P+
Sbjct: 145 IPPASPRLGNTSEAHGAARTAPPRPNVP------APPPPTPPPPPPPLPPPLPSSSPIKT 198
Query: 302 ALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKP 361
L P + PV AP V P AP PP P P P P L ++A+KP
Sbjct: 199 PLVSPPGPLTKGNLPVVAPPV-PCAPPPPPPPPPP-------TPPPLPPASVLSDKAVKP 250
Query: 362 GAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDG 421
A PL P PP LP PP PG+ AE + P Q +
Sbjct: 251 QLA--PLHLPPIPP-----PLPLLPP-----------CGYPGLKAEP---ASPAQDAQEP 289
Query: 422 PEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENA 481
P P P +P + +++ PP PP+ + + AP + A
Sbjct: 290 PAPPPPLPPYASCSPRASLPAP-PLPGVNSSSETPPPLPPK--------SPSFQAPPQKA 340
Query: 482 ELCTQAMALETPTPGPP---------REGQSPASQAGTQHPPAQATAHSQSS 524
A AL P P PP R G+ P + G +PP A S ++
Sbjct: 341 ----GAQALPAP-PAPPGSQPFLQKKRHGR-PGAGGGKLNPPPAPPARSPTT 386
Score = 63.9 bits (154), Expect = 7e-10
Identities = 97/360 (26%), Positives = 130/360 (36%), Gaps = 56/360 (15%)
Query: 186 PPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGND--RLWFVNPIFIEDC 243
PP G P PP P SSLR A ++ G ++ +N
Sbjct: 14 PPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQI 73
Query: 244 SSALPTDQPPLGNCPAR--PLPPTSD----ATSPTSRWAPRRPPP------------PPP 285
S+ T++ G+ R PPT P R A +R P P
Sbjct: 74 ESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSP 133
Query: 286 VLPLQPCS-PAQPPVLPAL-----APAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMM 339
LP + S P PP P L A A P P VPAP P P PP P PP+
Sbjct: 134 RLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAP--PPPTPPPPPPPLPPPLP 191
Query: 340 TCERLPCP-TAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLE 398
+ + P + GPL + + A P P PP P P PP +S++
Sbjct: 192 SSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPP-PPPPTPPPLPPASVLSDKAVKP 250
Query: 399 DQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPV 458
+P L LPP P P + + + P + A++PP
Sbjct: 251 QLAP--------LHLPPI-----PPPLPLLPPCGYPGLKAEPASP------AQDAQEPPA 291
Query: 459 -PPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREG--QSPASQAGTQHPPA 515
PPP S ++LPAP L + ETP P PP+ Q+P +AG Q PA
Sbjct: 292 PPPPLPPYASCSPRASLPAP----PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPA 347
Score = 46.2 bits (108), Expect = 2e-04
Identities = 64/266 (24%), Positives = 84/266 (31%), Gaps = 37/266 (13%)
Query: 280 PPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGP-------PDH 332
PPPPPP LP PP P AP P P P++PPV + P D
Sbjct: 4 PPPPPPPLP--------PPPPPLGAPPP--PPPSAPPVSTDTSSLRRADPKGRSALLADI 53
Query: 333 PNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPA---KKNLPTAPPRR 389
+ ++ +A + K G S+ + PP P P
Sbjct: 54 QQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAG 113
Query: 390 RVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPEL 449
+ Q PG A +L P T GP P S G +E + + P
Sbjct: 114 QRDVAGGKTGQGPGSRAPSPRL---PNKTISGPL-IPPASPRLGNTSEAHGAARTAPPRP 169
Query: 450 PRTAKQPPVPPPRKKRISRQLASTL---------PAPLENAELCTQAMALETPTPGPPRE 500
A PP PPP + L S+ P PL L A + P PP
Sbjct: 170 NVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPP-- 227
Query: 501 GQSPASQAGTQHPPAQATAHSQSSPE 526
P PPA + P+
Sbjct: 228 --PPPPPTPPPLPPASVLSDKAVKPQ 251
Score = 37.4 bits (85), Expect = 0.070
Identities = 39/142 (27%), Positives = 48/142 (33%), Gaps = 28/142 (19%)
Query: 246 ALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAP 305
A P PP +C +PR P PP LP S PP LP +P
Sbjct: 291 APPPPLPPYASC------------------SPRASLPAPP-LPGVNSSSETPPPLPPKSP 331
Query: 306 APACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAAS 365
+ P P P PP P P + +R P AG G L P A
Sbjct: 332 SFQAP-------PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPP--AR 382
Query: 366 SPLQQVPAPPLPAKKNLPTAPP 387
SP ++ + A PT P
Sbjct: 383 SPTTELSSKSQQATAWTPTQQP 404
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 66.2 bits (160), Expect = 1e-10
Identities = 80/288 (27%), Positives = 104/288 (36%), Gaps = 31/288 (10%)
Query: 244 SSALPTDQPPLGNCPARPLPPTSDATSPTSRW-APRRPPPPPPVLPL--QPCSPAQPPVL 300
++A+PT + P PA +PP + TSP + P P P +P +P SPA
Sbjct: 1017 AAAVPTPEEPTS--PAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1074
Query: 301 P--ALAPAPACPLPTSPPVPAPHV-TPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREE 357
P +PA A P P P PA V TP P P P P A P EE
Sbjct: 1075 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP-----EEPASPAAAVPTPEE 1129
Query: 358 AMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQG 417
P AA+ P + PA P PA +PT + V ++S AA + P +
Sbjct: 1130 PASP-AAAVPTPEEPAFPAPA---VPTPEESASAAVAVPTPEESASPAA---AVPTPAES 1182
Query: 418 TS-DGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPA 476
S T E T A+ ++ E A P LA+ +
Sbjct: 1183 ASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPT-----SEEPASLAAAVSN 1237
Query: 477 PLENAELCTQAMALETPTPG-----PPREGQSPASQAGTQHPPAQATA 519
P E LE PT P E SPA+ T PA A
Sbjct: 1238 PEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAA 1285
Score = 60.1 bits (144), Expect = 1e-08
Identities = 83/332 (25%), Positives = 122/332 (36%), Gaps = 36/332 (10%)
Query: 262 LPPTSDATSPTSRWAPR---RPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVP 318
+P T + +P P P P ++ +P +P A P P P + VP
Sbjct: 962 VPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP 1021
Query: 319 APHVTPHAPG----PPDHPNQP--PMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVP 372
P P +P PP+ P P + T E P A + P EE P AA+ P + P
Sbjct: 1022 TPE-EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAV-PTPEEPTSP-AAAVPTPEEP 1078
Query: 373 APPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQ 432
P A P P + E SP A + P PE+ P
Sbjct: 1079 TSPAAAVPT-PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEE-PASPAAA 1136
Query: 433 GQDTEVKASDPHSMPELPRTAKQP-PVPPPRKKRISRQLASTLPAPLENAELCTQAMALE 491
E A ++P +A VP P + S A+ +P P E+A LE
Sbjct: 1137 VPTPEEPAFPAPAVPTPEESASAAVAVPTPEE---SASPAAAVPTPAESASFAAVVATLE 1193
Query: 492 TPT------PGPP------REGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSL- 538
PT P P E SPA+ T PA A + S+PE S A+ +L
Sbjct: 1194 EPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAA-AVSNPEEPTSPAAAVPTLE 1252
Query: 539 ----GVSVMATDQDSYSTSSTEEELEQFSSPS 566
+ + T ++ S +++ E+ +SP+
Sbjct: 1253 EPTSSAAAVLTPEELSSPAASVPTPEEPASPA 1284
Score = 50.1 bits (118), Expect = 1e-05
Identities = 74/280 (26%), Positives = 102/280 (36%), Gaps = 36/280 (12%)
Query: 244 SSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPAL 303
++A+PT + P PA +P + TSP + P P P P + P PA
Sbjct: 1069 AAAVPTPEEPTS--PAAAVPTPEEPTSPAA-------AVPTPEEPTSPAAAVPTPEEPA- 1118
Query: 304 APAPACPLPTSPPVPAPHV-TPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPG 362
+PA A P P P PA V TP P P P + T E + P EE+ P
Sbjct: 1119 SPAAAVPTPEEPASPAAAVPTPEEPAFP----APAVPTPEESASAAVAV-PTPEESASPA 1173
Query: 363 AASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQG--TSD 420
AA VP P A A S S+ + M A ++ + P TS+
Sbjct: 1174 AA------VPTPAESASFAAVVATLEEPTSPAASVPTPA-AMVATLEEFTSPAASVPTSE 1226
Query: 421 GPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLEN 480
P + + T A+ P E P ++ + P + +S AS +P P E
Sbjct: 1227 EPASLAAAVSNPEEPTSPAAAVP--TLEEPTSSAAAVLTP---EELSSPAAS-VPTPEEP 1280
Query: 481 AELCTQAMALETPTP-----GPPREGQSPASQAGTQHPPA 515
A LE P P PA+ T PA
Sbjct: 1281 ASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPA 1320
Score = 35.0 bits (79), Expect = 0.35
Identities = 32/106 (30%), Positives = 37/106 (34%), Gaps = 18/106 (16%)
Query: 237 PIFIEDCSSALPTDQPPLGNCPARPLP----PTSDATS-----PTSRWAPRRPPPPPPVL 287
P E S A P PA +P PTS A + S A P P P
Sbjct: 1223 PTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPAS 1282
Query: 288 PLQPCSPAQPPVLPALA---------PAPACPLPTSPPVPAPHVTP 324
P S + P PA A PA + P P P +PA V P
Sbjct: 1283 PAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPP 1328
Score = 32.0 bits (71), Expect = 2.9
Identities = 26/111 (23%), Positives = 40/111 (36%), Gaps = 8/111 (7%)
Query: 237 PIFIEDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPP------PVLPLQ 290
P E SSA P + PA +P + SP + + P P P +
Sbjct: 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAI 1308
Query: 291 PCSPAQPPVLPALAPAPACPLPTSPPVPAPH--VTPHAPGPPDHPNQPPMM 339
P + P +PA+ A P+ P+ P V+ H P P++
Sbjct: 1309 PAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVL 1359
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 66.2 bits (160), Expect = 1e-10
Identities = 76/294 (25%), Positives = 104/294 (35%), Gaps = 37/294 (12%)
Query: 281 PPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMT 340
P PP+ P+ P P PV P AP+P P PP P P V P P+ PM +
Sbjct: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSV-GSMPSAGPMPSAGPMPS 691
Query: 341 CERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQ 400
P P+A GP A G + L VP LP +N ++
Sbjct: 692 AG--PVPSARPGP-PTTANHLGLSVPGLVSVPPRLLPGPENHRAG------------SNE 736
Query: 401 SPGMAAEG-DQLSLPPQGTSDGPEDTP---RESTEQGQDTEVKASD---------PHSMP 447
P +A G ++PP T G P E+ D E+ P +P
Sbjct: 737 DPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLP 796
Query: 448 ELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQ 507
LP PPP + +PA E EL L P P PP P
Sbjct: 797 PLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPP-----PVPG 851
Query: 508 AGTQHPPAQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQ 561
T PP + +P G A D +++ ++D++ EEE E+
Sbjct: 852 PVTLPPPQLV---PEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEE 902
Score = 47.4 bits (111), Expect = 7e-05
Identities = 47/139 (33%), Positives = 59/139 (42%), Gaps = 35/139 (25%)
Query: 215 HDANCACEIELSVGNDRLWFVNPIFIEDCSSALPTDQPPLGNCPARPLPPTSDATSPTSR 274
+D A ++E+S+ +D +D +P PPL P PP S AT P
Sbjct: 768 YDKEEASDVEISLESDS---------DDSVVIVPEGLPPL------PPPPPSGATPPPI- 811
Query: 275 WAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPN 334
AP PP P +P + +P LPA AP PLP PP P P PGP P
Sbjct: 812 -APTGPPTASPPVP----AKEEPEELPA-APG---PLPPPPPPPPP-----VPGPVTLP- 856
Query: 335 QPPMMTCERLPCPTAGLGP 353
PP + E P G GP
Sbjct: 857 -PPQLVPEGTP---GGGGP 871
Score = 41.2 bits (95), Expect = 0.005
Identities = 60/228 (26%), Positives = 79/228 (34%), Gaps = 45/228 (19%)
Query: 252 PPLGNCP-ARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACP 310
P G P ARP PPT+ S P PP +LP A P LAP+ P
Sbjct: 690 PSAGPVPSARPGPPTTANHLGLS--VPGLVSVPPRLLPGPENHRAGSNEDPILAPS-GTP 746
Query: 311 LPTSPP------------------------------------VPAPHVTPHAPGPPDHPN 334
PT PP V P P P PP
Sbjct: 747 PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGA 806
Query: 335 QPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSER 394
PP + P + + P +EE + AA PL P PP P + T PP + V E
Sbjct: 807 TPPPIAPTGPPTASPPV-PAKEEPEELPAAPGPLPPPPPPPPPVPGPV-TLPPPQLVPEG 864
Query: 395 VSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASD 442
G A + L++ +SD E+ E E+ ++ E + D
Sbjct: 865 T---PGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEED 909
Score = 36.6 bits (83), Expect = 0.12
Identities = 48/185 (25%), Positives = 63/185 (34%), Gaps = 37/185 (20%)
Query: 281 PPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMT 340
PPPP + P P + P V P P P L P T G P P
Sbjct: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEP-----GTEEERGADTAPTLAP--- 1028
Query: 341 CERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQ 400
E LP G + E P A PP + P+APP E ED
Sbjct: 1029 -EALP----SQGEVEREGESPAAG--------PPPQELVEEEPSAPPTLLEEE---TEDG 1072
Query: 401 SPGMAAEGDQLSLPPQGTSDGPEDTPRES----TEQGQDTEVKASDPHSMPELPRTAKQP 456
S D++ PP+ ++ +T E+ ++ DT +D P P K P
Sbjct: 1073 S-------DKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCP--PDDEKPP 1123
Query: 457 PVPPP 461
P P
Sbjct: 1124 PPTEP 1128
Score = 32.0 bits (71), Expect = 2.9
Identities = 45/178 (25%), Positives = 60/178 (33%), Gaps = 38/178 (21%)
Query: 261 PLPPTSDATSPTSRWAPR--RPPPPPPVLPLQPCSPAQ-----PPVLPALAPAPACPLPT 313
P PPT P P+ P P P L L+ P P LAP LP+
Sbjct: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPE---ALPS 1033
Query: 314 SPPVPAPHVTPHAPGPP-----DHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPL 368
V +P A PP + P+ PP L EE + G S +
Sbjct: 1034 QGEVEREGESPAAGPPPQELVEEEPSAPP---------------TLLEEETEDG--SDKV 1076
Query: 369 QQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTP 426
Q P P PA++ + T + E+ +Q A D + PP P P
Sbjct: 1077 Q--PPPETPAEEEMETETEAEALQEK----EQDDTAAMLADFIDCPPDDEKPPPPTEP 1128
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 65.9 bits (159), Expect = 2e-10
Identities = 62/257 (24%), Positives = 88/257 (34%), Gaps = 44/257 (17%)
Query: 247 LPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPA---- 302
+P +P +G+ P PP P R PP P P QP PP P
Sbjct: 169 MPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGT 228
Query: 303 ------------LAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERL-PCPTA 349
+ +P P PP P+ + P PP P + E + P P
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQ 288
Query: 350 GLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPR--------RRVSERVSLEDQS 401
P +P A+S Q P PP P++ P PP R +SL +
Sbjct: 289 NNKPPVPSTPRPSASS---QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345
Query: 402 PGMAAEGDQLSLPPQGTS------------DGPEDTPRESTEQGQDTEVKASDP----HS 445
P + + G LPP + GP P + G + + P S
Sbjct: 346 PPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRS 405
Query: 446 MPELPRTAKQPPVPPPR 462
+ PR+ +PP+PP R
Sbjct: 406 GVDSPRSGPRPPLPPDR 422
Score = 62.8 bits (151), Expect = 2e-09
Identities = 61/214 (28%), Positives = 80/214 (37%), Gaps = 31/214 (14%)
Query: 253 PLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPC--SPAQPPVLPALAPAPACP 310
P N P PLPPT SR +PPPPPP + +P A PP P P
Sbjct: 245 PFSNRP--PLPPTP------SRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP--- 293
Query: 311 LPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQ 370
+P++P A P P PP P PP LP ++G + + SS
Sbjct: 294 VPSTPRPSASSQAPPPPPPPSRPGPPP------LPPSSSGNDETPRLPQRNLSLSSSTPP 347
Query: 371 VPAP----PLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTP 426
+P+P PLP + PP R R P ++ G TS TP
Sbjct: 348 LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS--------TSRALPATP 399
Query: 427 RESTEQGQDTEVKASDPHSMPELPRTAKQPPVPP 460
+ + G D+ P P+ P PP PP
Sbjct: 400 QLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433
Score = 59.3 bits (142), Expect = 2e-08
Identities = 84/314 (26%), Positives = 112/314 (35%), Gaps = 57/314 (18%)
Query: 187 PQERGKPAEP--PRDRAPGF--PLVSSLRPTAHDANCACEIELSVGNDRLWFVN-PIFIE 241
P RG P P PR +PG P R TA + LS + F N P
Sbjct: 198 PHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP---FSNRPPLPP 254
Query: 242 DCSSAL----PTDQPPLGNCP-----ARPLPPTSD-----ATSPTSRWAPRRPPPPPPVL 287
S AL P PP+GN P A P PP + ++P + + PPPPPP
Sbjct: 255 TPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP-- 312
Query: 288 PLQPCSPAQPPVLPALAPAPACPL------PTSPPVPAPHVTPHAPGPPDHPNQPPMM-- 339
P +P P PP P P ++PP+P+P + P PP PP+
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372
Query: 340 --TCERLPCP--------TAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRR 389
LP P T+ P + SP + P PPLP + APP
Sbjct: 373 PGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP-RSGPRPPLPPDRPSAGAPPPP 431
Query: 390 RVSERVSLEDQSPGMAAEGDQ-------LSLPP-----QGTSDGPEDTPRESTEQGQDTE 437
S + Q E + LPP Q T P R + G +
Sbjct: 432 PPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRR 491
Query: 438 VKASDPHSMPELPR 451
+ + P +P +PR
Sbjct: 492 ERGAPP--LPPIPR 503
Score = 52.8 bits (125), Expect = 2e-06
Identities = 79/340 (23%), Positives = 112/340 (32%), Gaps = 72/340 (21%)
Query: 252 PPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPL 311
P LG +P + + RPP PP P PP P P P+
Sbjct: 98 PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH 157
Query: 312 PTSPPVP------------------APHVTPHAPGP----PDHPNQPPMMTCERLPCP-- 347
+ PP P P P P P P + PP+ R P P
Sbjct: 158 RSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGP 217
Query: 348 -----------TAGLGPLREEAMKPGAASSPL-QQVPAPPLPAK----KNLPTAPPRRRV 391
G G +R+ P ++SSP + P PP P++ K P PP V
Sbjct: 218 TPPPFPGNRGTALGGGSIRQ---SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP---V 271
Query: 392 SERVSLEDQ----------------SPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQD 435
R S+ + +P +A PP + GP P S+ +
Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET 331
Query: 436 TEV---KASDPHSMPELPRTAKQPPVPPPRKKRISRQL------ASTLPAPLENAELCTQ 486
+ S S P LP + P+PPP +R + + LP P + +
Sbjct: 332 PRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGST 391
Query: 487 AMALETPTPGPPREG-QSPASQAGTQHPPAQATAHSQSSP 525
+ AL P R G SP S PP + +A + P
Sbjct: 392 SRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPP 431
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,778,418
Number of Sequences: 37866
Number of extensions: 2918538
Number of successful extensions: 51665
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 521
Number of HSP's successfully gapped in prelim test: 1844
Number of HSP's that attempted gapping in prelim test: 21502
Number of HSP's gapped (non-prelim): 14181
length of query: 985
length of database: 18,247,518
effective HSP length: 112
effective length of query: 873
effective length of database: 14,006,526
effective search space: 12227697198
effective search space used: 12227697198
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.