BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33598929 scavenger receptor class F, member 1 isoform 1 precursor [Homo sapiens] (830 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 1832 0.0 gi|145309306 scavenger receptor class F, member 1 isoform 5 prec... 1166 0.0 gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 1164 0.0 gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 611 e-174 gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 608 e-174 gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 311 2e-84 gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 310 3e-84 gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 296 4e-80 gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 293 3e-79 gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 155 1e-37 gi|119703755 laminin, beta 2 precursor [Homo sapiens] 145 1e-34 gi|167614504 laminin, beta 1 precursor [Homo sapiens] 142 1e-33 gi|153946395 tenascin C precursor [Homo sapiens] 141 2e-33 gi|21264602 laminin alpha 5 [Homo sapiens] 139 1e-32 gi|148833508 notch1 preproprotein [Homo sapiens] 137 5e-32 gi|134244285 Notch homolog 3 [Homo sapiens] 135 2e-31 gi|143770880 laminin, beta 4 [Homo sapiens] 135 2e-31 gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 134 3e-31 gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 134 3e-31 gi|24041035 notch 2 preproprotein [Homo sapiens] 133 8e-31 gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 129 9e-30 gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] 129 1e-29 gi|55770876 notch4 preproprotein [Homo sapiens] 127 4e-29 gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] 127 4e-29 gi|9506545 delta-like 4 protein precursor [Homo sapiens] 122 1e-27 gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 122 1e-27 gi|4557679 jagged 1 precursor [Homo sapiens] 120 5e-27 gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] 119 1e-26 gi|110735443 delta-like 1 [Homo sapiens] 117 3e-26 gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like... 117 6e-26 >gi|33598929 scavenger receptor class F, member 1 isoform 1 precursor [Homo sapiens] Length = 830 Score = 1832 bits (4746), Expect = 0.0 Identities = 830/830 (100%), Positives = 830/830 (100%) Query: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP Sbjct: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60 Query: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC 120 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC Sbjct: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC 120 Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV Sbjct: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180 Query: 181 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP Sbjct: 181 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240 Query: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG 300 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG 300 Query: 301 TFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQ 360 TFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQ Sbjct: 301 TFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQ 360 Query: 361 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRD 420 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRD Sbjct: 361 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRD 420 Query: 421 TALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGTLTSLGST 480 TALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGTLTSLGST Sbjct: 421 TALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGTLTSLGST 480 Query: 481 LPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSAGWATDDSFSSDPESGEADEVPAYCV 540 LPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSAGWATDDSFSSDPESGEADEVPAYCV Sbjct: 481 LPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSAGWATDDSFSSDPESGEADEVPAYCV 540 Query: 541 PPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVSFAEGTKFAP 600 PPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVSFAEGTKFAP Sbjct: 541 PPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVSFAEGTKFAP 600 Query: 601 QSRRSSGELSSPLRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPAAASPGDSATGH 660 QSRRSSGELSSPLRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPAAASPGDSATGH Sbjct: 601 QSRRSSGELSSPLRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPAAASPGDSATGH 660 Query: 661 RRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLAGKPRGSEGPVRSVFRHFGSFQKGQA 720 RRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLAGKPRGSEGPVRSVFRHFGSFQKGQA Sbjct: 661 RRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLAGKPRGSEGPVRSVFRHFGSFQKGQA 720 Query: 721 EAKVKRAIPKPPRQALNRKKGSPGLASGSVGQSPNSAPKAGLPGATGPMAVRPEEAVRGL 780 EAKVKRAIPKPPRQALNRKKGSPGLASGSVGQSPNSAPKAGLPGATGPMAVRPEEAVRGL Sbjct: 721 EAKVKRAIPKPPRQALNRKKGSPGLASGSVGQSPNSAPKAGLPGATGPMAVRPEEAVRGL 780 Query: 781 GAGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEEPEYENVVPISRPPEP 830 GAGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEEPEYENVVPISRPPEP Sbjct: 781 GAGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEEPEYENVVPISRPPEP 830 >gi|145309306 scavenger receptor class F, member 1 isoform 5 precursor [Homo sapiens] Length = 744 Score = 1166 bits (3016), Expect = 0.0 Identities = 597/839 (71%), Positives = 622/839 (74%), Gaps = 104/839 (12%) Query: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP Sbjct: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60 Query: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC 120 DACQKDEVCVKP G C+C Sbjct: 61 DACQKDEVCVKP-------------------------------------------GLCRC 77 Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPG-WWSSTCRRPCQCNTAAARCEQATGAC 179 + +GA C C PG +W CR C C+ +CE ATGAC Sbjct: 78 KPGFFGAHCSSRC------------------PGQYWGPDCRESCPCHPHG-QCEPATGAC 118 Query: 180 VCKPGWWGRRCSFRCNC--HGSPCEQDSGRCACRPGWWGPECQQQCEC--VRGRCSAASG 235 C+ WG RC F C C HG C+ +G C C PGWW C++ C+C RC A+G Sbjct: 119 QCQADRWGARCEFPCACGPHGR-CDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATG 177 Query: 236 ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ 295 C C PG+ G RC C +C H PC D+G C +C PGW G +CQQ Sbjct: 178 ACVCKPGWWGRRCSFRC-----------NC----HGSPCEQDSGRC-ACRPGWWGPECQQ 221 Query: 296 PCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTC 355 C C G C +G C C PG+ G RCE PCP G+ G C +C Sbjct: 222 QC--------------ECVRGR-CSAASGECT-CPPGFRGARCELPCPAGSHGVQCAHSC 265 Query: 356 PTCVQGS-CDTVTGDCV-CSAGYWGPSCNASCPAGFHGNNCSVPC-ECPEG-LCHPVSGS 411 C C TG C C G+ G C C G G +C C C G C P +G Sbjct: 266 GRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGH 325 Query: 412 CQPGSGSRDTALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVW 471 CQ SGSRDTALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVW Sbjct: 326 CQRCSGSRDTALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVW 385 Query: 472 GTLTSLGSTLPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSAGWATDDSFSSDPESGE 531 GTLTSLGSTLPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSAGWATDDSFSSDPESGE Sbjct: 386 GTLTSLGSTLPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSAGWATDDSFSSDPESGE 445 Query: 532 ADEVPAYCVPPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVS 591 ADEVPAYCVPPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVS Sbjct: 446 ADEVPAYCVPPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVS 505 Query: 592 FAEGTKFAPQSRRSSGELSSPLRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPAAA 651 FAEGTKFAPQSRRSSGELSSPLRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPAAA Sbjct: 506 FAEGTKFAPQSRRSSGELSSPLRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPAAA 565 Query: 652 SPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLAGKPRGSEGPVRSVFRH 711 SPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLAGKPRGSEGPVRSVFRH Sbjct: 566 SPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLAGKPRGSEGPVRSVFRH 625 Query: 712 FGSFQKGQAEAKVKRAIPKPPRQALNRKKGSPGLASGSVGQSPNSAPKAGLPGATGPMAV 771 FGSFQKGQAEAKVKRAIPKPPRQALNRKKGSPGLASGSVGQSPNSAPKAGLPGATGPMAV Sbjct: 626 FGSFQKGQAEAKVKRAIPKPPRQALNRKKGSPGLASGSVGQSPNSAPKAGLPGATGPMAV 685 Query: 772 RPEEAVRGLGAGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEEPEYENVVPISRPPEP 830 RPEEAVRGLGAGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEEPEYENVVPISRPPEP Sbjct: 686 RPEEAVRGLGAGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEEPEYENVVPISRPPEP 744 >gi|33598931 scavenger receptor class F, member 1 isoform 3 precursor [Homo sapiens] Length = 569 Score = 1164 bits (3012), Expect = 0.0 Identities = 497/501 (99%), Positives = 497/501 (99%) Query: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP Sbjct: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60 Query: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC 120 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC Sbjct: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC 120 Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV Sbjct: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180 Query: 181 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP Sbjct: 181 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240 Query: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG 300 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG 300 Query: 301 TFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQ 360 TFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQ Sbjct: 301 TFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQ 360 Query: 361 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRD 420 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRD Sbjct: 361 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRD 420 Query: 421 TALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGTLTSLGST 480 TALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGTLTSLGST Sbjct: 421 TALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGTLTSLGST 480 Query: 481 LPCRSLSSHKLPWVTVSHHDP 501 LPCRSLSSHKLPWVT S P Sbjct: 481 LPCRSLSSHKLPWVTASSSRP 501 >gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo sapiens] Length = 870 Score = 611 bits (1575), Expect = e-174 Identities = 334/857 (38%), Positives = 432/857 (50%), Gaps = 67/857 (7%) Query: 6 LLPLLLLWTRG--TQGSELDPKGQHVCVASSPSAEL-QCCAGWRQKDQECTIPICEGPDA 62 LL LLLLW EL+P+G++VC A P +++ CCAGWRQ+ EC I +CEG Sbjct: 28 LLLLLLLWMLPDTVAPQELNPRGRNVCRA--PGSQVPTCCAGWRQQGDECGIAVCEGNST 85 Query: 63 CQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQA 122 C ++EVCV+PG CRC+ G+FGA+C ++CP Q+WGPDC+E C CHPHGQCE TG C C A Sbjct: 86 CSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHA 145 Query: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCK 182 RWGARCE C C HG C P +G C CEPGWW + C C C +A +RC+ TGAC+C Sbjct: 146 RRWGARCEHACQC-QHGTCHPRSGACRCEPGWWGAQCASACYC-SATSRCDPQTGACLCH 203 Query: 183 PGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPG 242 GWWGR C+ +C C+ SPCEQ SGRC CR +G C + C+C RGRC G C C PG Sbjct: 204 AGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPG 263 Query: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302 +RG C PCPAG +G+ C CG+CK +PC+ G C +CEPGWNGT+C QPC G + Sbjct: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323 Query: 303 GESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS 362 GE C +CP CR G AC TG C RC+ GW+G RCE C GT+GEDC C C G Sbjct: 324 GEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH 383 Query: 363 CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRDTA 422 CD +G C+CS G GP CN +CP G HG +C+ C C E C PV+G+C + R Sbjct: 384 CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACHLETNQRKGV 443 Query: 423 LIAGSLVPLLL-LFLGLACCACCCWAPRSDLKDRPARDGATVSRMKL--QVWGTLTSLGS 479 + AG+L+ LL+ L L L C C C + RP R+ ++ R K ++ G + + Sbjct: 444 MGAGALLVLLVCLLLSLLGCCCACRGKDPTRRPRPRRE-LSLGRKKAPHRLCGRFSRISM 502 Query: 480 TLPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSA------GWATDDSFSSDPESGEAD 533 LP L KLP V V+HHD + N SF+EPPS W++ SFSS D Sbjct: 503 KLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSS---FDTTD 559 Query: 534 EVPAYCVPPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVSFA 593 E P YCVP +E A A S + PE + P P S + S A Sbjct: 560 EGPVYCVPHEE-----APAESRD----------PEVPTVPAEAPAPSPVPLTTPASAEEA 604 Query: 594 EGTKFAPQSRRSSGELSSP-----LRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFP 648 + S RS+ + P R +R +R A++ E S PE + P P Sbjct: 605 IPLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDP 664 Query: 649 AAASPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLA-----GKPRGSEG 703 A G GR + E + S T A G PR + Sbjct: 665 ATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDP 724 Query: 704 PVRSVFRHFGSFQKGQAEAKVKRAIPKPPR---QALNRKKGSPG-LASGSVGQSPNSAPK 759 R G E A P PPR +A R G+ G S + S Sbjct: 725 TPR---------PPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLA 775 Query: 760 AGLPGATGPMAVRPEEAVRGLG-----AGTESSRRAQEPVSGCGSPEQDPQKQAEEERQE 814 A + G T + R E A+ G A + ++R+ P S +P E+ + Sbjct: 776 ADVRGKTRSLG-RAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATD 834 Query: 815 EPEYE---NVVPISRPP 828 P E PI +PP Sbjct: 835 LPAPETPRKKTPIQKPP 851 >gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo sapiens] Length = 865 Score = 608 bits (1568), Expect = e-174 Identities = 333/856 (38%), Positives = 430/856 (50%), Gaps = 70/856 (8%) Query: 6 LLPLLLLWTRG--TQGSELDPKGQHVCVASSPSAEL-QCCAGWRQKDQECTIPICEGPDA 62 LL LLLLW EL+P+G++VC A P +++ CCAGWRQ+ EC I +CEG Sbjct: 28 LLLLLLLWMLPDTVAPQELNPRGRNVCRA--PGSQVPTCCAGWRQQGDECGIAVCEGNST 85 Query: 63 CQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQA 122 C ++EVCV+PG CRC+ G+FGA+C ++CP Q+WGPDC+E C CHPHGQCE TG C C A Sbjct: 86 CSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHA 145 Query: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCK 182 RWGARCE C C HG C P +G C CEPGWW + C C C +A +RC+ TGAC+C Sbjct: 146 RRWGARCEHACQC-QHGTCHPRSGACRCEPGWWGAQCASACYC-SATSRCDPQTGACLCH 203 Query: 183 PGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPG 242 GWWGR C+ +C C+ SPCEQ SGRC CR +G C + C+C RGRC G C C PG Sbjct: 204 AGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPG 263 Query: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302 +RG C PCPAG +G+ C CG+CK +PC+ G C +CEPGWNGT+C QPC G + Sbjct: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323 Query: 303 GESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS 362 GE C +CP CR G AC TG C RC+ GW+G RCE C GT+GEDC C C G Sbjct: 324 GEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH 383 Query: 363 CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRDTA 422 CD +G C+CS G GP CN +CP G HG +C+ C C E C PV+G+C + R Sbjct: 384 CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACHLETNQRKGV 443 Query: 423 LIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKL--QVWGTLTSLGST 480 + AG+L+ LL+ L L+ CCC D P R ++ R K ++ G + + Sbjct: 444 MGAGALLVLLVCLL-LSLLGCCCACRGKD----PTRRELSLGRKKAPHRLCGRFSRISMK 498 Query: 481 LPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSA------GWATDDSFSSDPESGEADE 534 LP L KLP V V+HHD + N SF+EPPS W++ SFSS DE Sbjct: 499 LPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSS---FDTTDE 555 Query: 535 VPAYCVPPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVSFAE 594 P YCVP +E A A S + PE + P P S + S A Sbjct: 556 GPVYCVPHEE-----APAESRD----------PEVPTVPAEAPAPSPVPLTTPASAEEAI 600 Query: 595 GTKFAPQSRRSSGELSSP-----LRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPA 649 + S RS+ + P R +R +R A++ E S PE + P PA Sbjct: 601 PLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPA 660 Query: 650 AASPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLA-----GKPRGSEGP 704 G GR + E + S T A G PR + Sbjct: 661 TKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPT 720 Query: 705 VRSVFRHFGSFQKGQAEAKVKRAIPKPPR---QALNRKKGSPG-LASGSVGQSPNSAPKA 760 R G E A P PPR +A R G+ G S + S A Sbjct: 721 PR---------PPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAA 771 Query: 761 GLPGATGPMAVRPEEAVRGLG-----AGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEE 815 + G T + R E A+ G A + ++R+ P S +P E+ + Sbjct: 772 DVRGKTRSLG-RAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATDL 830 Query: 816 PEYE---NVVPISRPP 828 P E PI +PP Sbjct: 831 PAPETPRKKTPIQKPP 846 >gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] Length = 1140 Score = 311 bits (797), Expect = 2e-84 Identities = 158/436 (36%), Positives = 209/436 (47%), Gaps = 63/436 (14%) Query: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99 QCC G+ + + C +P C D C C+ P C+C+PG+ G +CSS C G +WGP C Sbjct: 93 QCCPGFYESGEMC-VPHCA--DKCVHGR-CIAPNTCQCEPGWGGTNCSSACDGDHWGPHC 148 Query: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-------------CDPATG 146 C C C P TGAC C A G RCE C G +G CD TG Sbjct: 149 TSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTG 208 Query: 147 VCHCEPGWWSSTCRRPCQCNTAAARCEQ------------ATGACVCKPGW--------- 185 C C PG+ + C C +CEQ TG C C GW Sbjct: 209 ECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPC 268 Query: 186 ----WGRRCSFRCNCH-GSPCEQDSGRCACRPGWWGPECQQQ-------------CECVR 227 +G+ CS C CH G C+ +G+C C PG+ G CQ + C+CV Sbjct: 269 PEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVN 328 Query: 228 -GRCSAASGECTCPPGFRGARCELP-CPAGSHGVQCAHSCG-RCKHNEPCSPDTGSCESC 284 G+C SG C C GF G RCE CP G +G++C C ++ C P +G C +C Sbjct: 329 GGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGEC-AC 387 Query: 285 EPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPT 344 +PGW+G C + C PG +GE+C+Q C C++G C+ TG C C PG+ G C PCP Sbjct: 388 KPGWSGLYCNETCSPGFYGEACQQIC-SCQNGADCDSVTGKC-TCAPGFKGIDCSTPCPL 445 Query: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE-G 403 GT+G +C S C C V G C C AG+ G C+ CP+G G C++ C+C G Sbjct: 446 GTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGG 505 Query: 404 LCHPVSGSCQPGSGSR 419 C+ + G+C G R Sbjct: 506 ACNTLDGTCTCAPGWR 521 Score = 309 bits (792), Expect = 6e-84 Identities = 162/439 (36%), Positives = 199/439 (45%), Gaps = 65/439 (14%) Query: 44 GWRQKD---QECTIPICEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDC 99 GWR +D Q C CQ C G CRC PG+ GA C CP GP C Sbjct: 175 GWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQC 234 Query: 100 RESCPCHPHGQCEPATGACQCQAD-------------RWGARCEFPCACGPHGRCDPATG 146 + CPC G C TG C C + R+G C C C G CD ATG Sbjct: 235 EQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATG 294 Query: 147 VCHCEPGWWSSTCRRPCQCNTAAA------------RCEQATGACVCKPGWWGRRCSFR- 193 CHC PG+ C+ C T +C +GAC+C+ G+ G RC R Sbjct: 295 QCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARL 354 Query: 194 -------------CNCH---GSPCEQDSGRCACRPGW-------------WGPECQQQCE 224 C CH C SG CAC+PGW +G CQQ C Sbjct: 355 CPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICS 414 Query: 225 CVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCES 283 C G C + +G+CTC PGF+G C PCP G++G+ C+ CG CK++ CSP GSC + Sbjct: 415 CQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCG-CKNDAVCSPVDGSC-T 472 Query: 284 CEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCP 343 C+ GW+G C C GT+G C C C +G AC G C C PGW G +CE PC Sbjct: 473 CKAGWHGVDCSIRCPSGTWGFGCNLTC-QCLNGGACNTLDGTCT-CAPGWRGEKCELPCQ 530 Query: 344 TGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEG 403 GT+G +C C C TG C C G+ G C++ C G G NCS+PC C G Sbjct: 531 DGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNG 590 Query: 404 L-CHPVSGSCQPGSGSRDT 421 C P G C+ G R T Sbjct: 591 ASCSPDDGICECAPGFRGT 609 Score = 283 bits (723), Expect = 6e-76 Identities = 151/445 (33%), Positives = 190/445 (42%), Gaps = 67/445 (15%) Query: 36 SAELQCCAGWRQK--DQECTIPI----CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSS 88 S E C GW ++ C+ C+ +CQ C G C C PGF G CS+ Sbjct: 382 SGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCST 441 Query: 89 RCPGQYWGPDCRESCPCHPHGQCEPATGACQCQAD-------------RWGARCEFPCAC 135 CP +G +C C C C P G+C C+A WG C C C Sbjct: 442 PCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQC 501 Query: 136 GPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ------------ATGACVCKP 183 G C+ G C C PGW C PCQ T C + TG C C P Sbjct: 502 LNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLP 561 Query: 184 GW-------------WGRRCSFRCNC-HGSPCEQDSGRCACRPGWWGPECQQQC------ 223 GW WG CS C C +G+ C D G C C PG+ G CQ+ C Sbjct: 562 GWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYG 621 Query: 224 --------ECVR--GRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEP 273 +CV G C +G C C PGF GA C CP+G G CA C C +N Sbjct: 622 HRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGIC-TCTNNGT 680 Query: 274 CSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGW 333 C+P SC+ C PGW G+ C QPC P +G +C C +C +G C G C +C PGW Sbjct: 681 CNPIDRSCQ-CYPGWIGSDCSQPCPPAHWGPNCIHTC-NCHNGAFCSAYDGEC-KCTPGW 737 Query: 334 LGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNN 393 G C CP G +G+DC C CD ++G C C G+ G C CP+G +G Sbjct: 738 TGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYG 797 Query: 394 CSVPCEC-PEGLCHPVSGSCQPGSG 417 C C+C C ++G+C G Sbjct: 798 CRQICDCLNNSTCDHITGTCYCSPG 822 Score = 250 bits (639), Expect = 3e-66 Identities = 139/412 (33%), Positives = 176/412 (42%), Gaps = 68/412 (16%) Query: 34 SPSAELQCCAGWRQKDQECTIPI------CEGPDACQKDEVCVK-PGLCRCKPGFFGAHC 86 S + + C G++ D P+ C C+ D VC G C CK G+ G C Sbjct: 423 SVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC 482 Query: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHG-----RC 141 S RCP WG C +C C G C G C C G +CE PC G +G RC Sbjct: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERC 542 Query: 142 D--------PATGVCHCEPGW-------------WSSTCRRPCQCNTAAARCEQATGAC- 179 D P TG C C PGW W C PC C A+ C G C Sbjct: 543 DCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGAS-CSPDDGICE 601 Query: 180 ------------VCKPGWWGRRCSFRC-NC-HGS-PCEQDSGRCACRPGWWGPECQQQCE 224 +C PG++G RCS C C H S PC +G C C PG+ G C + C Sbjct: 602 CAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCP 661 Query: 225 CVR--------------GRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKH 270 R G C+ C C PG+ G+ C PCP G C H+C C + Sbjct: 662 SGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCN-CHN 720 Query: 271 NEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCD 330 CS G C+ C PGW G C Q C G +G+ C C C++G C+ +G C C Sbjct: 721 GAFCSAYDGECK-CTPGWTGLYCTQRCPLGFYGKDCALIC-QCQNGADCDHISGQCT-CR 777 Query: 331 PGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCN 382 G++G CE CP+GT+G C C +CD +TG C CS G+ G C+ Sbjct: 778 TGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCD 829 Score = 186 bits (471), Expect = 1e-46 Identities = 103/319 (32%), Positives = 127/319 (39%), Gaps = 68/319 (21%) Query: 41 CCAGWRQKDQECTIPICEGP---------DACQKDEVCVKPGLCRCKPGFFGAHCSSRCP 91 C GWR ++C +P +G D D G CRC PG+ G HC S C Sbjct: 516 CAPGWR--GEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCA 573 Query: 92 GQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR----------- 140 WGP+C C C C P G C+C G C+ C+ G +G Sbjct: 574 EGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVH 633 Query: 141 ----CDPATGVCHCEPGWWSSTCRRPCQCN------------TAAARCEQATGACVCKPG 184 C TG+C C PG+ + C C T C +C C PG Sbjct: 634 SSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPG 693 Query: 185 W-------------WGRRCSFRCNCH-GSPCEQDSGRCACRPGWWGPECQQQC------- 223 W WG C CNCH G+ C G C C PGW G C Q+C Sbjct: 694 WIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGK 753 Query: 224 ------ECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSP 276 +C G C SG+CTC GF G CE CP+G++G C C C +N C Sbjct: 754 DCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICD-CLNNSTCDH 812 Query: 277 DTGSCESCEPGWNGTQCQQ 295 TG+C C PGW G +C Q Sbjct: 813 ITGTCY-CSPGWKGARCDQ 830 Score = 119 bits (299), Expect = 9e-27 Identities = 64/209 (30%), Positives = 82/209 (39%), Gaps = 41/209 (19%) Query: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQAD--------- 123 GLC C PGF GA C+ CP +G +C C C +G C P +CQC Sbjct: 643 GLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQP 702 Query: 124 ----RWGARCEFPCACGPHGRCDPATGVCHCEPGW-------------WSSTCRRPCQCN 166 WG C C C C G C C PGW + C CQC Sbjct: 703 CPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQ 762 Query: 167 TAAARCEQATGACVCKPGWWGRRCSFRC-------------NC-HGSPCEQDSGRCACRP 212 A C+ +G C C+ G+ GR C +C +C + S C+ +G C C P Sbjct: 763 NGAD-CDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSP 821 Query: 213 GWWGPECQQQCECVRGRCSAASGECTCPP 241 GW G C Q + G ++ S T P Sbjct: 822 GWKGARCDQAGVIIVGNLNSLSRTSTALP 850 >gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] Length = 1044 Score = 310 bits (795), Expect = 3e-84 Identities = 164/439 (37%), Positives = 205/439 (46%), Gaps = 57/439 (12%) Query: 18 QGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPI------CEGPDACQKDEVCVK 71 +G +L + +H + E C G+ E P CE CQ C Sbjct: 183 KGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHH 242 Query: 72 -PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCE 130 G C C PG+ GA C+ CP +G +C + CPCH GQC+ TG C C A G RC+ Sbjct: 243 ITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQ 302 Query: 131 FPCA-------CGPH------GRCDPATGVCHCEPGWWSSTCRR--------------PC 163 C C H G+C P TG C CEPG+ C+ PC Sbjct: 303 EECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPC 362 Query: 164 QCNTA-AARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222 C+ C TGAC C+PGW G C+ +C G++G CQ Sbjct: 363 PCDADNTISCHPVTGACTCQPGWSGHHCNE----------------SCPVGYYGDGCQLP 406 Query: 223 CECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSC 281 C C G C + +G CTC PGF G C + C AG++G C+ C C + CSP GSC Sbjct: 407 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICS-CNNGGTCSPVDGSC 465 Query: 282 ESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDP 341 +C+ GW G C PC GT+G +C + C C +G AC P G C C PGWLG CE P Sbjct: 466 -TCKEGWQGLDCTLPCPSGTWGLNCNESCT-CANGAACSPIDGSCS-CTPGWLGDTCELP 522 Query: 342 CPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECP 401 CP GTFG +C C CD VTG C C AG+ G C+++CP G G NCSV C C Sbjct: 523 CPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE 582 Query: 402 E-GLCHPVSGSCQPGSGSR 419 G C P GSC+ G R Sbjct: 583 NGGSCSPEDGSCECAPGFR 601 Score = 304 bits (779), Expect = 2e-82 Identities = 158/429 (36%), Positives = 201/429 (46%), Gaps = 63/429 (14%) Query: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99 QCC G+ + C IP+C + C CV P C C+PG+ G CSS C +WGP C Sbjct: 87 QCCPGYYESGDFC-IPLCT--EECVHGR-CVSPDTCHCEPGWGGPDCSSGCDSDHWGPHC 142 Query: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-------------CDPATG 146 C C C P TGAC C A G RCE CA G HG+ CDP G Sbjct: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAG 202 Query: 147 VCHCEPGWWSSTCRRPCQCNTAAARCE------------QATGACVCKPGW--------- 185 C C PG+ C C + A CE TG C C PGW Sbjct: 203 ECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPC 262 Query: 186 ----WGRRCSFRCNC-HGSPCEQDSGRCACRPGWWGPECQQQC-------ECVR------ 227 +G+ CS C C HG C+ +G+C C G+ G CQ++C +C + Sbjct: 263 PPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHN 322 Query: 228 -GRCSAASGECTCPPGFRGARC-ELPCPAGSHGVQCAHSCGRCKHNE-PCSPDTGSCESC 284 G+CS +G C C PG++G RC E CP G HG C C N C P TG+C +C Sbjct: 323 GGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGAC-TC 381 Query: 285 EPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPT 344 +PGW+G C + C G +G+ C+ C C++G C TG C C PG++G C C Sbjct: 382 QPGWSGHHCNESCPVGYYGDGCQLPCT-CQNGADCHSITGGC-TCAPGFMGEVCAVSCAA 439 Query: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEG- 403 GT+G +C S C G+C V G C C G+ G C CP+G G NC+ C C G Sbjct: 440 GTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGA 499 Query: 404 LCHPVSGSC 412 C P+ GSC Sbjct: 500 ACSPIDGSC 508 Score = 288 bits (738), Expect = 1e-77 Identities = 152/440 (34%), Positives = 181/440 (41%), Gaps = 67/440 (15%) Query: 41 CCAGWRQKDQECTIPI------CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQ 93 C GW + P+ C+ P CQ C G C C PGF G C+ C Sbjct: 381 CQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAG 440 Query: 94 YWGPDCRESCPCHPHGQCEPATGACQCQ-------------ADRWGARCEFPCACGPHGR 140 +GP+C C C+ G C P G+C C+ + WG C C C Sbjct: 441 TYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAA 500 Query: 141 CDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ------------ATGACVCKPGW--- 185 C P G C C PGW TC PC T C + TG C C GW Sbjct: 501 CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGI 560 Query: 186 ----------WGRRCSFRCNC-HGSPCEQDSGRCACRPGWWGPECQQQCE---------- 224 WG CS C+C +G C + G C C PG+ GP CQ+ C Sbjct: 561 RCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQ 620 Query: 225 ----CVRGR--CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDT 278 CV C SG C C PGF GA C C G G CA C C +N CSP Sbjct: 621 PCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCS-CANNGTCSPID 679 Query: 279 GSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRC 338 GSC+ C PGW G C Q C PG +G +C C C +G +C + G C C PGW G C Sbjct: 680 GSCQ-CFPGWIGKDCSQACPPGFWGPACFHACS-CHNGASCSAEDGACH-CTPGWTGLFC 736 Query: 339 EDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPC 398 CP FG+DCG C SCD ++G C C G+ G C C G G C C Sbjct: 737 TQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLC 796 Query: 399 EC-PEGLCHPVSGSCQPGSG 417 EC C V+G+C G Sbjct: 797 ECMNNSTCDHVTGTCYCSPG 816 Score = 286 bits (733), Expect = 4e-77 Identities = 149/422 (35%), Positives = 179/422 (42%), Gaps = 63/422 (14%) Query: 55 PICEGPDACQKDE-VCVKP--GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQC 111 P C P C D + P G C C+PG+ G HC+ CP Y+G C+ C C C Sbjct: 356 PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADC 415 Query: 112 EPATGAC-------------QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGW---- 154 TG C C A +G C C+C G C P G C C+ GW Sbjct: 416 HSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLD 475 Query: 155 ---------WSSTCRRPCQCNTAAARCEQATGACVCKPGW-------------WGRRCSF 192 W C C C AA C G+C C PGW +G CS Sbjct: 476 CTLPCPSGTWGLNCNESCTCANGAA-CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSE 534 Query: 193 RCNC-HGSPCEQDSGRCACRPGW-------------WGPECQQQCECVRG-RCSAASGEC 237 C+C H C+ +G C C GW WGP C C C G CS G C Sbjct: 535 HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSC 594 Query: 238 TCPPGFRGARCELPCPAGSHGVQCAHSCGRCKH-NEPCSPDTGSCESCEPGWNGTQCQQP 296 C PGFRG C+ CP G +G CA C C H + PC +G CE C PG++G C Q Sbjct: 595 ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICE-CLPGFSGALCNQV 653 Query: 297 CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCP 356 C G FG+ C Q C C + C P G CQ C PGW+G C CP G +G C C Sbjct: 654 CAGGYFGQDCAQLC-SCANNGTCSPIDGSCQ-CFPGWIGKDCSQACPPGFWGPACFHACS 711 Query: 357 TCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL-CHPVSGSCQPG 415 SC G C C+ G+ G C CPA F G +C C+C G C +SG C Sbjct: 712 CHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCR 771 Query: 416 SG 417 +G Sbjct: 772 TG 773 Score = 224 bits (570), Expect = 3e-58 Identities = 110/268 (41%), Positives = 136/268 (50%), Gaps = 25/268 (9%) Query: 150 CEPGWWSST--CRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGR 207 C PG++ S C C RC + C C+PGW G CS S C+ D Sbjct: 88 CCPGYYESGDFCIPLCTEECVHGRCV-SPDTCHCEPGWGGPDCS-------SGCDSDH-- 137 Query: 208 CACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG 266 WGP C +C+C G C+ +G C C GFRG RCE C G+HG C C Sbjct: 138 -------WGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPC- 189 Query: 267 RCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326 +C+H C P G C C PG+ G C++ C PG+ G CE +CP C++G C TG C Sbjct: 190 QCRHGASCDPRAGEC-LCAPGYTGVYCEELCPPGSHGAHCELRCP-CQNGGTCHHITGEC 247 Query: 327 QRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCP 386 C PGW G C PCP GTFG++C CP G CD VTG C C+AGY G C CP Sbjct: 248 A-CPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECP 306 Query: 387 AGFHGNNCSVPCECPE-GLCHPVSGSCQ 413 G G CS C+C G C P +G+C+ Sbjct: 307 FGSFGFQCSQHCDCHNGGQCSPTTGACE 334 Score = 175 bits (444), Expect = 1e-43 Identities = 103/332 (31%), Positives = 131/332 (39%), Gaps = 69/332 (20%) Query: 32 ASSP-SAELQCCAGWRQKDQECTIPICEGPDACQKDEVC---------VKPGLCRCKPGF 81 A SP C GW C +P +G E C G C C G+ Sbjct: 500 ACSPIDGSCSCTPGWL--GDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGW 557 Query: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR- 140 G C S CP WGP+C SC C G C P G+C+C G C+ C G +G Sbjct: 558 TGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHG 617 Query: 141 --------------CDPATGVCHCEPGWWSSTCRRPCQ-----------CNTAA-ARCEQ 174 C +G+C C PG+ + C + C C+ A C Sbjct: 618 CAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSP 677 Query: 175 ATGACVCKPGW-------------WGRRCSFRCNCH-GSPCEQDSGRCACRPGW------ 214 G+C C PGW WG C C+CH G+ C + G C C PGW Sbjct: 678 IDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCT 737 Query: 215 -------WGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG 266 +G +C + C+C G C SG+CTC GF G CE C G+ G C C Sbjct: 738 QRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLC- 796 Query: 267 RCKHNEPCSPDTGSCESCEPGWNGTQCQQPCL 298 C +N C TG+C C PG+ G +C Q L Sbjct: 797 ECMNNSTCDHVTGTCY-CSPGFKGIRCDQAAL 827 Score = 60.1 bits (144), Expect = 8e-09 Identities = 36/125 (28%), Positives = 46/125 (36%), Gaps = 11/125 (8%) Query: 33 SSPSAELQCCAGWRQK--DQECTIPI----CEGPDACQKDEVCVK-PGLCRCKPGFFGAH 85 S+ C GW Q C C CQ C G C C+ GF G H Sbjct: 719 SAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQH 778 Query: 86 CSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPC----ACGPHGRC 141 C RC +G C++ C C + C+ TG C C G RC+ P+ + Sbjct: 779 CEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNPYTKI 838 Query: 142 DPATG 146 PA G Sbjct: 839 SPALG 843 Score = 56.6 bits (135), Expect = 9e-08 Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 5/75 (6%) Query: 348 GEDCGSTCPT-CVQGSCDTVTGD-CVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEG-L 404 G+ C C CV G C V+ D C C G+ GP C++ C + G +CS C+C G L Sbjct: 96 GDFCIPLCTEECVHGRC--VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGAL 153 Query: 405 CHPVSGSCQPGSGSR 419 C+P++G+C +G R Sbjct: 154 CNPITGACVCAAGFR 168 >gi|122937343 platelet endothelial aggregation receptor 1 [Homo sapiens] Length = 1037 Score = 296 bits (759), Expect = 4e-80 Identities = 173/497 (34%), Positives = 209/497 (42%), Gaps = 115/497 (23%) Query: 30 CVASSPSAELQCCAGWRQKD--QECTI----PICEGPDACQKDEVC-VKPGLCRCKPGFF 82 CVA + + QC GWR D EC P C+ P +C + C K G+C C G Sbjct: 114 CVAPN---QCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQ 170 Query: 83 GAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCD 142 +C C Y+GP C+ C CH C+P TGAC C A+R G C+ C+ G G Sbjct: 171 PPNCLQPCTPGYYGPACQFRCQCHG-APCDPQTGACFCPAERTGPSCDVSCSQGTSGFFC 229 Query: 143 PAT-------------GVCHCEPGWWSSTCRRPC-------------------------- 163 P+T G C C PGW + C PC Sbjct: 230 PSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTG 289 Query: 164 QCNTAA-----------------------------ARCEQATGACVCKPGWWGRRCSFR- 193 QC A ARC A GAC+C+ G+ G RC+ R Sbjct: 290 QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRL 349 Query: 194 -------------CNC---HGSPCEQDSGRCACRPGW-------------WGPECQQQCE 224 C C H C +G C+C PGW GP CQ+ C Sbjct: 350 CPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCL 409 Query: 225 CVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCES 283 C+ G C A SG C C PG+ G C CP ++GV C+ C C++ CSP G C Sbjct: 410 CLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCS-CENAIACSPIDGECV- 467 Query: 284 CEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCP 343 C+ GW C PC PGT+G SC C C H C P TG C C PGW G C+ PCP Sbjct: 468 CKEGWQRGNCSVPCPPGTWGFSCNASC-QCAHEAVCSPQTGACT-CTPGWHGAHCQLPCP 525 Query: 344 TGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE- 402 G FGE C S C CD V G C C AG+ G C+ SCP G G NCS C C Sbjct: 526 KGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNG 585 Query: 403 GLCHPVSGSCQPGSGSR 419 G C P +G+C G R Sbjct: 586 GTCLPENGNCVCAPGFR 602 Score = 293 bits (749), Expect = 6e-79 Identities = 160/489 (32%), Positives = 206/489 (42%), Gaps = 112/489 (22%) Query: 31 VASSPSAELQCCAGWRQKDQECTIPICEG---PDA-----CQKDEVCVK-PGLCRCKPGF 81 V +P C GW C++P EG P+ C +C + G CRC PG+ Sbjct: 240 VFQTPQGSCSCPPGWM--GTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGY 297 Query: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQ--------ADR------WGA 127 G C CP +G DC E+C C P +C PA GAC C+ DR +G Sbjct: 298 TGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGL 357 Query: 128 RCEFPCACGPHGR--CDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ----------- 174 C+ PC C C P G C C PGW C C +T C++ Sbjct: 358 SCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQ 417 Query: 175 -ATGACVCKPGW-------------WGRRCSFRCNCHGS-PCEQDSGRCACRPGW----- 214 +G C C PG+ +G CS RC+C + C G C C+ GW Sbjct: 418 ATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNC 477 Query: 215 --------WGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSC 265 WG C C+C CS +G CTC PG+ GA C+LPCP G G CA C Sbjct: 478 SVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRC 537 Query: 266 GRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGH 325 C H++ C P G C+ C+ GW G +C C G +G +C C C++G C P+ G+ Sbjct: 538 D-CDHSDGCDPVHGRCQ-CQAGWMGARCHLSCPEGLWGVNCSNTCT-CKNGGTCLPENGN 594 Query: 326 C---------------------QRCDP--------------------GWLGPRCEDPCPT 344 C +RC P GW GP C PCP Sbjct: 595 CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPP 654 Query: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC-PEG 403 G +GE+C TC G+C G C+C G+ G C CP G G NCS PC+C P Sbjct: 655 GHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGE 714 Query: 404 LCHPVSGSC 412 CHP +G+C Sbjct: 715 KCHPETGAC 723 Score = 266 bits (679), Expect = 8e-71 Identities = 135/382 (35%), Positives = 166/382 (43%), Gaps = 63/382 (16%) Query: 57 CEGPDACQKDE-VCVKP--GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEP 113 C+ P C ++ + P G C C PG+ G HC+ CP GP C+E C C G C+ Sbjct: 359 CQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQA 418 Query: 114 ATGACQCQA-------------DRWGARCEFPCACGPHGRCDPATGVCHCEPGW------ 154 +G CQC D +G C C+C C P G C C+ GW Sbjct: 419 TSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCS 478 Query: 155 -------WSSTCRRPCQCNTAAARCEQATGACVCKPGW-------------WGRRCSFRC 194 W +C CQC A C TGAC C PGW +G C+ RC Sbjct: 479 VPCPPGTWGFSCNASCQCAHEAV-CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRC 537 Query: 195 NC-HGSPCEQDSGRCACRPGW-------------WGPECQQQCECVRG-RCSAASGECTC 239 +C H C+ GRC C+ GW WG C C C G C +G C C Sbjct: 538 DCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVC 597 Query: 240 PPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLP 299 PGFRG C+ C G +G +C +C ++ C P G+C C GW G C QPC P Sbjct: 598 APGFRGPSCQRSCQPGRYGKRCVPC--KCANHSFCHPSNGTCY-CLAGWTGPDCSQPCPP 654 Query: 300 GTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCV 359 G +GE+C Q C C HG C P G C C GW G C + CP GTFG +C C Sbjct: 655 GHWGENCAQTC-QCHHGGTCHPQDGSCI-CPLGWTGHHCLEGCPLGTFGANCSQPCQCGP 712 Query: 360 QGSCDTVTGDCVCSAGYWGPSC 381 C TG CVC G+ G C Sbjct: 713 GEKCHPETGACVCPPGHSGAPC 734 Score = 160 bits (405), Expect = 5e-39 Identities = 89/282 (31%), Positives = 110/282 (39%), Gaps = 64/282 (22%) Query: 31 VASSP-SAELQCCAGWRQKDQECTIPI--------CEGPDACQKDEVCV-KPGLCRCKPG 80 +A SP E C GW++ + C++P C C + VC + G C C PG Sbjct: 457 IACSPIDGECVCKEGWQRGN--CSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPG 514 Query: 81 FFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQAD-------------RWGA 127 + GAHC CP +G C C C C+P G CQCQA WG Sbjct: 515 WHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGV 574 Query: 128 RCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARC-----------EQAT 176 C C C G C P G C C PG+ +C+R CQ RC + Sbjct: 575 NCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSN 634 Query: 177 GACVCKPGW-------------WGRRCSFRCNCH-GSPCEQDSGRCACRPGW-------- 214 G C C GW WG C+ C CH G C G C C GW Sbjct: 635 GTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEG 694 Query: 215 -----WGPECQQQCECVRG-RCSAASGECTCPPGFRGARCEL 250 +G C Q C+C G +C +G C CPPG GA C + Sbjct: 695 CPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRI 736 Score = 96.7 bits (239), Expect = 8e-20 Identities = 51/157 (32%), Positives = 64/157 (40%), Gaps = 22/157 (14%) Query: 19 GSELDPKGQHVCVAS--SPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCR 76 G+ L G VC PS + C G + + C C C G C Sbjct: 586 GTCLPENGNCVCAPGFRGPSCQRSCQPG--RYGKRCVPCKCANHSFCHPSN-----GTCY 638 Query: 77 CKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGAC-------------QCQAD 123 C G+ G CS CP +WG +C ++C CH G C P G+C C Sbjct: 639 CLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLG 698 Query: 124 RWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCR 160 +GA C PC CGP +C P TG C C PG + CR Sbjct: 699 TFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCR 735 >gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] Length = 1541 Score = 293 bits (751), Expect = 3e-79 Identities = 158/420 (37%), Positives = 186/420 (44%), Gaps = 62/420 (14%) Query: 55 PICEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEP 113 P CE CQ C G C C G+ G C CP ++G DCR +C C C+ Sbjct: 911 PGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDA 970 Query: 114 ATGACQCQADRWGARC-------------EFPCACGPHGRCDPATGVCHCEPGW------ 154 G+C C A R G RC CAC CDP G CHC PGW Sbjct: 971 VNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCL 1030 Query: 155 -------WSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRC------------- 194 + CR C C C+ +G C C GW G C C Sbjct: 1031 QACPAGLYGDNCRHSCLCQNGGT-CDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSG 1089 Query: 195 NC-HGSPCEQDSGRCACRPGWWGPECQ-------------QQCECVRGR-CSAASGECTC 239 C +G C+ +GRC C GW G +CQ Q+C C G C +G C C Sbjct: 1090 GCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRC 1149 Query: 240 PPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLP 299 PPGF G+ CE CP GS G CA C N C P TG+C SC G++G CQQ C P Sbjct: 1150 PPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC-SCAAGYHGPSCQQRCPP 1208 Query: 300 GTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCV 359 G +G CEQ C C +G +C+ TG C RC G+LG C CP G FG +C C C Sbjct: 1209 GRYGPGCEQLCG-CLNGGSCDAATGAC-RCPTGFLGTDCNLTCPQGRFGPNCTHVCG-CG 1265 Query: 360 QGS-CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEG-LCHPVSGSCQPGSG 417 QG+ CD VTG C+C G G C CP G C C C G LCH +GSC G G Sbjct: 1266 QGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLG 1325 Score = 290 bits (743), Expect = 3e-78 Identities = 171/493 (34%), Positives = 206/493 (41%), Gaps = 114/493 (23%) Query: 23 DPK-GQHVCVASSPSAELQ--CCAGWRQKDQECTIPICEGPDACQKDEVC-VKPGLCRCK 78 DP+ G +C+ + Q C AGW P C+ +C D C G C C Sbjct: 796 DPETGACLCLPGFVGSRCQDVCPAGWYG-------PSCQTRCSCANDGHCHPATGHCSCA 848 Query: 79 PGFFGAHCSSRCPGQYWGPDCRESCPCHP-HGQCEPATGACQCQADRWGARCEFPCACGP 137 PG+ G C C +WGPDC C C HG C+ +G C C+A G RCE C G Sbjct: 849 PGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGH 908 Query: 138 HG-------------RCDPATGVCHCEPGWWSSTCRRPCQ-----------CN-TAAARC 172 G CD +G C C GW + C C CN TA A C Sbjct: 909 FGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC 968 Query: 173 EQATGACVCKPGWWGRRCSFRCNCH--------------GSPCEQDSGRCACRPGWWGPE 218 + G+C+C G G RC+ C H G+ C+ G+C C PGW GP Sbjct: 969 DAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPS 1028 Query: 219 CQQQC-----------ECV---RGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHS 264 C Q C C+ G C SG C CP G+ G CE C C HS Sbjct: 1029 CLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHS 1088 Query: 265 CGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTG 324 G C + C P TG C C GW G +CQ PCL G FGE+C Q+C C G AC TG Sbjct: 1089 -GGCLNGGLCDPHTGRC-LCPAGWTGDKCQSPCLRGWFGEACAQRCS-CPPGAACHHVTG 1145 Query: 325 HCQRCDPGWLGPRCEDPCPTGTFGEDCGSTC------------------------PTCVQ 360 C RC PG+ G CE CP G+FGEDC C P+C Q Sbjct: 1146 AC-RCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQ 1204 Query: 361 --------------------GSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC 400 GSCD TG C C G+ G CN +CP G G NC+ C C Sbjct: 1205 RCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGC 1264 Query: 401 PEG-LCHPVSGSC 412 +G C PV+G+C Sbjct: 1265 GQGAACDPVTGTC 1277 Score = 290 bits (742), Expect = 4e-78 Identities = 152/425 (35%), Positives = 190/425 (44%), Gaps = 73/425 (17%) Query: 55 PICEGPDACQKDEVCVKP---------GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPC 105 P GP C ++ CV+P G C CK GF G C + C Y+GP C ++C C Sbjct: 643 PWAFGP-GCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTC 701 Query: 106 HPHGQCEPATGAC---------------QCQADRWGARCEFPCACGPHGRCDPATGVCHC 150 C+ +G C +C +G C C+CG C TG C C Sbjct: 702 PVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGG-APCHGVTGQCRC 760 Query: 151 EPGW-------------WSSTCRRPCQCNTAAARCEQATGACVCKPG------------- 184 PG W C+ C AARC+ TGAC+C PG Sbjct: 761 PPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAG 820 Query: 185 WWGRRCSFRCNC-HGSPCEQDSGRCACRPGW-------------WGPECQQQCECVRGR- 229 W+G C RC+C + C +G C+C PGW WGP+C C C G Sbjct: 821 WYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHG 880 Query: 230 -CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGW 288 C A SG C C G+ G RCE CP G G C C +C+H C +G+C +C GW Sbjct: 881 SCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRC-QCQHGAACDHVSGAC-TCPAGW 938 Query: 289 NGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFG 348 GT C+ C G FG C C +C G AC+ G C C G GPRC + CP T+G Sbjct: 939 RGTFCEHACPAGFFGLDCRSAC-NCTAGAACDAVNGSCL-CPAGRRGPRCAETCPAHTYG 996 Query: 349 EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE-GLCHP 407 +C C SCD V G C C+ G+ GPSC +CPAG +G+NC C C G C P Sbjct: 997 HNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDP 1056 Query: 408 VSGSC 412 VSG C Sbjct: 1057 VSGHC 1061 Score = 283 bits (725), Expect = 4e-76 Identities = 146/396 (36%), Positives = 172/396 (43%), Gaps = 61/396 (15%) Query: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132 G C C PG+ G C CP +G +CR SC C G C+P +G C C G CE Sbjct: 1016 GQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKE 1075 Query: 133 C-------------ACGPHGRCDPATGVCHCEPGWWSSTCRRPC-------------QCN 166 C C G CDP TG C C GW C+ PC C Sbjct: 1076 CLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCP 1135 Query: 167 TAAARCEQATGACVCKPGW-------------WGRRCSFRCNCHGS--PCEQDSGRCACR 211 AA C TGAC C PG+ +G C+ C C G C +G C+C Sbjct: 1136 PGAA-CHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCA 1194 Query: 212 PGWWGPECQQQCECVR--------------GRCSAASGECTCPPGFRGARCELPCPAGSH 257 G+ GP CQQ+C R G C AA+G C CP GF G C L CP G Sbjct: 1195 AGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRF 1254 Query: 258 GVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGE 317 G C H CG C C P TG+C C PG G +C++ C FG CE C CR+G Sbjct: 1255 GPNCTHVCG-CGQGAACDPVTGTC-LCPPGRAGVRCERGCPQNRFGVGCEHTCS-CRNGG 1311 Query: 318 ACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYW 377 C G C C GW G CE CP G +G C C +C+ TG C C G++ Sbjct: 1312 LCHASNGSCS-CGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY 1370 Query: 378 GPSCNASCPAGFHGNNCSVPCECPEGL-CHPVSGSC 412 G +C CP GFHG C C C G C P+SG C Sbjct: 1371 GQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRC 1406 Score = 277 bits (709), Expect = 3e-74 Identities = 157/452 (34%), Positives = 196/452 (43%), Gaps = 77/452 (17%) Query: 61 DACQKDEVCVKPGL--CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGAC 118 D C+ C+ GL C C G+ G C+ CP +G +C SC C G C+ TGAC Sbjct: 525 DDCRNGGTCLL-GLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGAC 583 Query: 119 Q-------------CQADRWGARCEFPCACGPHGRCDPATGVCHCEPG------------ 153 + C +G C C C GRC G C C+PG Sbjct: 584 RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPP 643 Query: 154 W-WSSTCRRPCQC-NTAAARCEQATGACVCKPGWWGRRCSFRCNCH-------------- 197 W + C CQC C++ G+C CK G+ G RC C Sbjct: 644 WAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPV 703 Query: 198 GSPCEQDSGRCA---------------CRPGWWGPECQQQCECVRGRCSAASGECTCPPG 242 G C+ SG C C G +G C C C C +G+C CPPG Sbjct: 704 GVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPG 763 Query: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302 G CE CP G G+ C C C+H C P+TG+C C PG+ G++CQ C G + Sbjct: 764 RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGAC-LCLPGFVGSRCQDVCPAGWY 822 Query: 303 GESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCP-TCVQG 361 G SC+ +C C + C P TGHC C PGW G C+ C TG +G DC C + G Sbjct: 823 GPSCQTRC-SCANDGHCHPATGHCS-CAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHG 880 Query: 362 SCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEG-LCHPVSGSCQPGSGSRD 420 SCD ++G C+C AGY GP C CP G G C C+C G C VSG+C +G R Sbjct: 881 SCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRG 940 Query: 421 T----ALIAGSLVPLLLLFLGLAC-CACCCWA 447 T A AG F GL C AC C A Sbjct: 941 TFCEHACPAG--------FFGLDCRSACNCTA 964 Score = 268 bits (684), Expect = 2e-71 Identities = 152/411 (36%), Positives = 185/411 (45%), Gaps = 63/411 (15%) Query: 41 CCAGWRQKDQECTIPICEG--PDACQKDEVCVK-------PGLCRCKPGFFGAHCSSRCP 91 C AGW +C P G +AC + C G CRC PGF G+ C CP Sbjct: 1106 CPAGWT--GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACP 1163 Query: 92 GQYWGPDCRESCPCHPHGQ-CEPATGACQCQAD-------------RWGARCEFPCACGP 137 +G DC + C C C PATG C C A R+G CE C C Sbjct: 1164 PGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLN 1223 Query: 138 HGRCDPATGVCHCEPGW-------------WSSTCRRPCQCNTAAARCEQATGACVCKPG 184 G CD ATG C C G+ + C C C AA C+ TG C+C PG Sbjct: 1224 GGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAA-CDPVTGTCLCPPG 1282 Query: 185 WWGRRCSFRC--NCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPG 242 G RC C N G CE C+CR G G C A++G C+C G Sbjct: 1283 RAGVRCERGCPQNRFGVGCEHT---CSCRNG--------------GLCHASNGSCSCGLG 1325 Query: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302 + G CEL CP G +G C C C +N C P TG+C C PG+ G C+ PC PG Sbjct: 1326 WTGRHCELACPPGRYGAACHLECS-CHNNSTCEPATGTCR-CGPGFYGQACEHPCPPGFH 1383 Query: 303 GESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS 362 G C+ C C+HG C+P +G C C G+ G CE C G+FGE C C Sbjct: 1384 GAGCQGLC-WCQHGAPCDPISGRCL-CPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAP 1441 Query: 363 CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL-CHPVSGSC 412 CD VTG C+C G G +CN C G G +C++ C+C G C PVSG C Sbjct: 1442 CDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQC 1492 Score = 186 bits (471), Expect = 1e-46 Identities = 108/334 (32%), Positives = 140/334 (41%), Gaps = 80/334 (23%) Query: 159 CRRPCQCNTAAARCEQATGACVCKPGW-------------WGRRCSFRCNC-HGSPCEQD 204 C C C C C GW +G+ CSF C+C +G C+ Sbjct: 520 CSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSV 579 Query: 205 SGRCACRP-------------GWWGPECQQQCECV-RGRCSAASGECTCPPGFRGARCEL 250 +G C C P G++G C+++C C RGRC G C C PG G C L Sbjct: 580 TGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHL 639 Query: 251 PCPAGSHGVQCAHSCGRC--KHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQ 308 CP + G C+ C +C H + C GSC SC+ G+ G +CQ C G FG C Q Sbjct: 640 TCPPWAFGPGCSEEC-QCVQPHTQSCDKRDGSC-SCKAGFRGERCQAECELGYFGPGCWQ 697 Query: 309 QCPHCRHGEACEPDTGHC-QRCDPGWLGPRCEDPCPTGTFGEDCGST------------- 354 C C G AC+ +G C +RC G+ G C CP GTFG +C S+ Sbjct: 698 ACT-CPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG 756 Query: 355 -----------------------------CPTCVQGS-CDTVTGDCVCSAGYWGPSCNAS 384 CP C + CD TG C+C G+ G C Sbjct: 757 QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV 816 Query: 385 CPAGFHGNNCSVPCECP-EGLCHPVSG--SCQPG 415 CPAG++G +C C C +G CHP +G SC PG Sbjct: 817 CPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPG 850 Score = 145 bits (365), Expect = 2e-34 Identities = 136/510 (26%), Positives = 175/510 (34%), Gaps = 121/510 (23%) Query: 27 QHVCVASSPSAELQCCAGWRQKDQECT---IPICE-GPDACQKD--EVCVKPGLCRCKPG 80 QH CV + S +C G+R T I C G CQ ++ + C+C+PG Sbjct: 173 QHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPG 232 Query: 81 FF----GAHCSSRCPGQYWGPDCRESCP---------CHPHGQ-------CEP----ATG 116 F G HC R P C C CH Q CE A G Sbjct: 233 FQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAG 292 Query: 117 ACQCQADRWGARCEFPCAC------GPHGR------------CDPATG------------ 146 QC + F C C G GR C+ G Sbjct: 293 LAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAG 352 Query: 147 -VCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRC--SFRCNCHGSPCEQ 203 +C C G+ T +R C A C PG + C +R + G CE Sbjct: 353 PLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE- 411 Query: 204 DSGRCACRPGWWGPECQQ-----QCECVRGR--------CSAAS-------GECTCP--- 240 D CA G C QC C G CS GE Sbjct: 412 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL 471 Query: 241 PGFRGARCELP----------------------------CPAGSHGVQCAHSCGRCKHNE 272 P + ELP C S G C+ +C C++ Sbjct: 472 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG 531 Query: 273 PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPG 332 C C+ C GW G C + C P TFG++C C C++G C+ TG C RC PG Sbjct: 532 TCLLGLDGCD-CPEGWTGLICNETCPPDTFGKNCSFSCS-CQNGGTCDSVTGAC-RCPPG 588 Query: 333 WLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGN 392 G CED CP G +G+ C C +G C + G C+C G +G C+ +CP G Sbjct: 589 VSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGP 648 Query: 393 NCSVPCECPE---GLCHPVSGSCQPGSGSR 419 CS C+C + C GSC +G R Sbjct: 649 GCSEECQCVQPHTQSCDKRDGSCSCKAGFR 678 Score = 80.1 bits (196), Expect = 8e-15 Identities = 101/424 (23%), Positives = 134/424 (31%), Gaps = 110/424 (25%) Query: 13 WTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQE--CTIPICEGPDACQKDEVCV 70 W G + + G + L+CC GW Q+ E C C +C Sbjct: 82 WCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSA-------SLCF 134 Query: 71 KPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCE 130 G RC PG + CP + GP C+ + +C G CQ Sbjct: 135 HGG--RCVPG---SAQPCHCPPGFQGPRCQ-----YDVDECRTHNGGCQ----------- 173 Query: 131 FPCACGPHGRC--DPATGVCHCEPGWWSSTCRRPCQCNTAAA--------RCEQAT---G 177 RC P + +C C+PG+ T R C + A C Q T Sbjct: 174 --------HRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH 225 Query: 178 ACVCKPGWW----GRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAA 233 C C+PG+ GR C R SPC +G C +C+ VRG Sbjct: 226 RCQCRPGFQLQEDGRHCVRR-----SPCANRNG-----------SCMHRCQVVRGLA--- 266 Query: 234 SGECTCPPGFR----GARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWN 289 C C G++ G CE + QCAH C + + C G E G + Sbjct: 267 --RCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGY----ELGAD 320 Query: 290 GTQCQQ-------PCLPGTFGESCEQQCPHCRHGEACEPDTGH--------CQRCDPGWL 334 G QC + C G C C H G C G+ C D Sbjct: 321 GRQCYRIEMEIVNSCEANNGG--CSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD 378 Query: 335 GPRCEDPCPTGTFGEDCG---------STCPTCVQGSCDTVTGDCVCSAGYWGPSCNASC 385 P C+ C G +CG C C + G C S SC Sbjct: 379 SPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSC 438 Query: 386 PAGF 389 AG+ Sbjct: 439 EAGY 442 Score = 70.9 bits (172), Expect = 5e-12 Identities = 71/255 (27%), Positives = 89/255 (34%), Gaps = 51/255 (20%) Query: 184 GWWGRRCSFRCNCHGSPCEQDSGR-CACRPGWWGPECQ---QQCECVRGRC------SAA 233 G CS HG C S + C C PG+ GP CQ +C G C + Sbjct: 122 GCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPG 181 Query: 234 SGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGW----N 289 S C C PGFR C A + CA G C+H+ T C PG+ + Sbjct: 182 SYLCECKPGFRLHTDSRTCLAIN---SCALGNGGCQHHCVQLTITRHRCQCRPGFQLQED 238 Query: 290 GTQC--QQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTF 347 G C + PC SC +C R CE G+ D G CED Sbjct: 239 GRHCVRRSPC--ANRNGSCMHRCQVVRGLARCECHVGYQLAAD----GKACEDV------ 286 Query: 348 GEDCGSTCPTCVQGSCDTV-TGDCVCSAGYW----GPSC--------------NASCPAG 388 ++C + C G +T + CVC AGY G C N C G Sbjct: 287 -DECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG 345 Query: 389 FHGNNCSVPCECPEG 403 + C CP G Sbjct: 346 CSHTSAGPLCTCPRG 360 Score = 53.5 bits (127), Expect = 8e-07 Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 5/73 (6%) Query: 57 CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATG 116 C+G C D V GLC C PG GA C+ C +GP C C C C+P +G Sbjct: 1436 CDGGAPC--DPVT---GLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSG 1490 Query: 117 ACQCQADRWGARC 129 C C G C Sbjct: 1491 QCHCVDGYMGPTC 1503 Score = 40.4 bits (93), Expect = 0.007 Identities = 37/133 (27%), Positives = 43/133 (32%), Gaps = 31/133 (23%) Query: 284 CEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCE---D 340 C GW QQP G C C HG C P + C PG+ GPRC+ D Sbjct: 110 CCRGW----MQQPDEEGCLSAECSASL--CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVD 163 Query: 341 PCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC 400 C T G Q C G +C C GF + S C Sbjct: 164 ECRTHNGG----------CQHRCVNTPGSYLC-----------ECKPGFRLHTDSRTCLA 202 Query: 401 PEGLCHPVSGSCQ 413 C +G CQ Sbjct: 203 INS-CALGNGGCQ 214 >gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] Length = 4242 Score = 155 bits (393), Expect = 1e-37 Identities = 148/468 (31%), Positives = 176/468 (37%), Gaps = 122/468 (26%) Query: 23 DPKGQHVCVASSPSAELQC---------CAGWR------QKDQECTIPICEGPDACQKDE 67 DP + +S PSA C C R C P C G CQ Sbjct: 169 DPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGD--CQGRG 226 Query: 68 VCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCP--CHPHGQCEPATGACQCQADRW 125 CV+ G+C C+ GF G CS R SCP C G+CE G C C Sbjct: 227 RCVQ-GVCVCRAGFSGPDCSQR------------SCPRGCSQRGRCE--GGRCVCDPGYT 271 Query: 126 GARC---EFPCACGPHGRCDPATGVCHCEPGWWSSTCR-RPCQCN-TAAARCEQATGACV 180 G C P C GRC+ G C C PG+ C R C + RC+ G CV Sbjct: 272 GDDCGMRSCPRGCSQRGRCE--NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKD--GRCV 327 Query: 181 CKPGWWGRRCSFRC---NC-HGSPCEQDSGRCACRPGWWGPECQQQC---ECVRGRCSAA 233 C PG+ G C R +C G C GRC C PG+ G +C + +C RGR Sbjct: 328 CDPGYTGEDCGTRSCPWDCGEGGRCV--DGRCVCWPGYTGEDCSTRTCPRDC-RGRGRCE 384 Query: 234 SGECTCPPGFRGARCEL-PCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQ 292 GEC C G+ G C + CP G C C + G C C PG+ GT Sbjct: 385 DGECICDTGYSGDDCGVRSCP------------GDCNQRGRC--EDGRC-VCWPGYTGTD 429 Query: 293 CQQPCLP------------------GTFGESC-EQQCP-HCRHGEACEPDTGHCQRCDPG 332 C P G GE C + CP CR CE +G C C PG Sbjct: 430 CGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCE--SGRCM-CWPG 486 Query: 333 WLG---------------PRCED---PCPTGTFGEDCGS-TCPTCVQGSCDTVTGDCVCS 373 + G RC D C G GEDCGS CP +G G CVC Sbjct: 487 YTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCD 546 Query: 374 AGYWGPSCNA-SCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRD 420 AGY G C+ SCP G G +C +G C C+ G D Sbjct: 547 AGYSGEDCSTRSCPGGCRGRG-----QCLDGRC-----VCEDGYSGED 584 Score = 137 bits (344), Expect = 5e-32 Identities = 120/389 (30%), Positives = 144/389 (37%), Gaps = 67/389 (17%) Query: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99 +C +C + C G C + C + G C C PG+ G C SR Sbjct: 387 ECICDTGYSGDDCGVRSCPGD--CNQRGRC-EDGRCVCWPGYTGTDCGSR---------- 433 Query: 100 RESCP--CHPHGQCEPATGACQCQADRWGARC---EFPCACGPHGRCDPATGVCHCEPGW 154 +CP C G+CE G C C A G C P C GRC+ +G C C PG+ Sbjct: 434 --ACPRDCRGRGRCE--NGVCVCNAGYSGEDCGVRSCPGDCRGRGRCE--SGRCMCWPGY 487 Query: 155 WSSTCRRPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCHGSPCEQDSGRCA 209 C R G CVC PG+ G RRC C HG CE G C Sbjct: 488 TGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGL-CE--DGVCV 544 Query: 210 CRPGWWGPECQQQCEC---VRGRCSAASGECTCPPGFRGARC---ELPCPAGSHGVQCAH 263 C G+ G +C + C RGR G C C G+ G C + P HGV C Sbjct: 545 CDAGYSGEDCSTR-SCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGV-CQD 602 Query: 264 S---CGRCKHNEPCSPDT--------GSCES----CEPGWNGTQCQQPCLPGTF--GESC 306 C +E CS T G CE C+PG+ G C P C Sbjct: 603 GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662 Query: 307 EQQCPHCR---HGEACEPDTGHCQRCDPGWLGPR--C---EDPCPTGTFGEDCG-STCPT 357 Q C GE C + C PG GPR C + C G G DC TCP Sbjct: 663 VQGVCLCHVGYGGEDCGQEEPPASAC-PGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPG 721 Query: 358 CVQGSCDTVTGDCVCSAGYWGPSCNASCP 386 +G + G CVC GY G C P Sbjct: 722 DCRGRGECHDGSCVCKDGYAGEDCGEEVP 750 Score = 79.3 bits (194), Expect = 1e-14 Identities = 82/308 (26%), Positives = 102/308 (33%), Gaps = 110/308 (35%) Query: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLC 75 G + D +G+ C S C G+ +D C C G C+ CV G C Sbjct: 462 GVRSCPGDCRGRGRC----ESGRCMCWPGYTGRD--CGTRACPGD--CRGRGRCVD-GRC 512 Query: 76 RCKPGFFGAHCSSR-CPGQ-----------------YWGPDCR-ESCP--CHPHGQCEPA 114 C PGF G C SR CPG Y G DC SCP C GQC Sbjct: 513 VCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQC--L 570 Query: 115 TGACQCQADRWGARC---EFPCACGPHGRCDPATGVCHCEPGWWSSTCR-RPCQCNT-AA 169 G C C+ G C + P C HG C GVC C G+ S C R C N Sbjct: 571 DGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD--GVCICWEGYVSEDCSIRTCPSNCHGR 628 Query: 170 ARCEQATGACVCKPGWWGRRCSFR----------------CNCH----GSPCEQDS---- 205 RCE+ G C+C PG+ G C+ R C CH G C Q+ Sbjct: 629 GRCEE--GRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPAS 686 Query: 206 ---------------------------------------------GRCACRPGWWGPECQ 220 G C C+ G+ G +C Sbjct: 687 ACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCG 746 Query: 221 QQCECVRG 228 ++ + G Sbjct: 747 EEVPTIEG 754 >gi|119703755 laminin, beta 2 precursor [Homo sapiens] Length = 1798 Score = 145 bits (367), Expect = 1e-34 Identities = 124/419 (29%), Positives = 156/419 (37%), Gaps = 80/419 (19%) Query: 54 IPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQY-WGPDCRESCPCHPHGQ-- 110 +P P E G C CKPG G C PG Y +GP ++C C G Sbjct: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALS 840 Query: 111 --CEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTA 168 CE +G C C+ +G RC+ C+ G W RPC CN Sbjct: 841 SLCEKTSGQCLCRTGAFGLRCD------------------RCQRGQWGFPSCRPCVCNGH 882 Query: 169 AARCEQATGACV-CKPGWWGRRCSFRC--NCHGSPCEQDSGRCACRPGWWGPECQQQ--C 223 A C TGAC+ C+ G C RC HG P G+C P GP Q+ Sbjct: 883 ADECNTHTGACLGCRDHTGGEHCE-RCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFAT 941 Query: 224 ECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK-----------HNE 272 C + S C C G+ G RCE P H + GRC+ + Sbjct: 942 SCHQDEYSQQI-VCHCRAGYTGLRCEACAP--GHFGDPSRPGGRCQLCECSGNIDPMDPD 998 Query: 273 PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA-------------- 318 C P TG C C G C C PG G++ Q C C Sbjct: 999 ACDPHTGQCLRCLHHTEGPHCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCH 1057 Query: 319 CEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCV-------QGSCDTVTGDCV 371 C+P +G C C P GP C D C + G C C +C+ TG C Sbjct: 1058 CDPSSGQCP-CLPNVQGPSC-DRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCH 1115 Query: 372 CSAGYWGPSCNASCPA---GFHGNNCSVPCEC-PEGL----CHPVSG--SCQPG-SGSR 419 C AG+ G +C + C G G C C+C G+ CH +G SC+PG SG R Sbjct: 1116 CRAGFGGRTC-SECQELHWGDPGLQCHA-CDCDSRGIDTPQCHRFTGHCSCRPGVSGVR 1172 Score = 105 bits (263), Expect = 1e-22 Identities = 118/420 (28%), Positives = 146/420 (34%), Gaps = 123/420 (29%) Query: 15 RGTQGSELDPKG-QHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKP- 72 +G+ SE +P G Q +C CA C+ +C K Sbjct: 788 QGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTS 847 Query: 73 GLCRCKPGFFGAHCSSRCPGQYWG-PDCRESCPCHPHG-QCEPATGACQ-CQADRWGARC 129 G C C+ G FG C RC WG P CR C C+ H +C TGAC C+ G C Sbjct: 848 GQCLCRTGAFGLRCD-RCQRGQWGFPSCRP-CVCNGHADECNTHTGACLGCRDHTGGEHC 905 Query: 130 EF------------------PCAC--GPHGRCDPATG----------VCHCEPGWWSSTC 159 E PC C GP + AT VCHC G+ C Sbjct: 906 ERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRC 965 Query: 160 R-----------RP------CQCN-----TAAARCEQATGACV-------------CKPG 184 RP C+C+ C+ TG C+ CKPG Sbjct: 966 EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPG 1025 Query: 185 WWG---RRCSFRCNCH---------GSP----CEQDSGRCACRPGWWGPECQ-------- 220 + G R+ RC C+ SP C+ SG+C C P GP C Sbjct: 1026 FHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWN 1085 Query: 221 -------QQCECVRGR-----CSAASGECTCPPGFRGARCELPCPA---GSHGVQCAHSC 265 Q C C R C+ +G+C C GF G C C G G+QC H+C Sbjct: 1086 LTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-ECQELHWGDPGLQC-HAC 1143 Query: 266 ---GRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPD 322 R C TG C SC PG +G +C Q C G G P C AC D Sbjct: 1144 DCDSRGIDTPQCHRFTGHC-SCRPGVSGVRCDQ-CARGFSG-----IFPACHPCHACFGD 1196 Score = 58.5 bits (140), Expect = 2e-08 Identities = 53/185 (28%), Positives = 71/185 (38%), Gaps = 65/185 (35%) Query: 70 VKPGLCR-CKPGFFGAHCSSRCPGQYWGP--DCRE-----SCPCHPHG-----QCE---- 112 V G+C C+ G HC P Y P D R+ SC C P G +C+ Sbjct: 369 VSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDD 428 Query: 113 PA----TGACQCQADRWGARCEF-----------------PCACGPHGR------CDPAT 145 PA +G C+C+ G RC+ C C G CDP + Sbjct: 429 PALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNS 488 Query: 146 GVCHCE------------PGWWSST-----CRRPCQCNTAAA---RCEQATGACVCKPGW 185 G C+C+ PG W + CR PC C+ A +C++ TG C C+ Sbjct: 489 GSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCR-PCDCDVGGALDPQCDEGTGQCHCRQHM 547 Query: 186 WGRRC 190 GRRC Sbjct: 548 VGRRC 552 Score = 51.2 bits (121), Expect = 4e-06 Identities = 73/286 (25%), Positives = 92/286 (32%), Gaps = 61/286 (21%) Query: 160 RRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGP-- 217 R C C A+ C A GA G C + N G CEQ P W P Sbjct: 280 RGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLP--WRPAE 337 Query: 218 ----ECQQQCECVRGRCSA--------ASGECT------CPPGFRGARCELPCP----AG 255 ++CEC S ASG + C G CEL P Sbjct: 338 DGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDP 397 Query: 256 SHGVQCAHSCGRCKHNEPCSPDTGSCES--------------CEPGWNGTQCQQPCLPGT 301 + ++ C C + S D G C+S C+ GT+CQQ C G Sbjct: 398 TKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGF 456 Query: 302 FGESCEQQ--CPHCR--------HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFG--- 348 FG S + C C+ C+P++G C C G C D C G +G Sbjct: 457 FGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCY-CKRLVTGRGC-DRCLPGHWGLSH 514 Query: 349 -----EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGF 389 C + CD TG C C G C P F Sbjct: 515 DLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560 Score = 47.8 bits (112), Expect = 4e-05 Identities = 51/205 (24%), Positives = 66/205 (32%), Gaps = 43/205 (20%) Query: 235 GECTCPPGFRGARCE--------LPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286 G C C RG CE LP G +H+C +C+ C T SC Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGH--SHACRKCE----CHGHTHSCHFDMA 361 Query: 287 GWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCED------ 340 + + G C C+H A HC+ C P + +D Sbjct: 362 VYLAS-----------GNVSGGVCDGCQHNTAGR----HCELCRPFFYRDPTKDLRDPAV 406 Query: 341 --PCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPC 398 C G G C + + V+G C C G C C GF G + S Sbjct: 407 CRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQ-QCRDGFFGLSISDRL 465 Query: 399 ECPEGLCH-----PVSGSCQPGSGS 418 C C+ P S C P SGS Sbjct: 466 GCRRCQCNARGTVPGSTPCDPNSGS 490 Score = 47.0 bits (110), Expect = 7e-05 Identities = 35/121 (28%), Positives = 46/121 (38%), Gaps = 34/121 (28%) Query: 73 GLCRCKPGFFGAHCSSRCPGQYWGPD------CRESCPCHPHGQ------CEPATGACQC 120 G CRCK G C +C ++G CR C C+ G C+P +G+C C Sbjct: 436 GQCRCKEHVVGTRCQ-QCRDGFFGLSISDRLGCRR-CQCNARGTVPGSTPCDPNSGSCYC 493 Query: 121 Q-------ADR-----WGARCEF----PCACGPHG----RCDPATGVCHCEPGWWSSTCR 160 + DR WG + PC C G +CD TG CHC C Sbjct: 494 KRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCE 553 Query: 161 R 161 + Sbjct: 554 Q 554 >gi|167614504 laminin, beta 1 precursor [Homo sapiens] Length = 1786 Score = 142 bits (358), Expect = 1e-33 Identities = 113/388 (29%), Positives = 155/388 (39%), Gaps = 74/388 (19%) Query: 73 GLCRCKPGFFGAHCSSRCPGQY-WGPDCRESCPCHPHGQ----CEPATGACQCQADRWGA 127 G C+C+P G C+ PG + +GP + C CH G C P TG C C + Sbjct: 790 GQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYAR 849 Query: 128 RCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV-CKPGWW 186 +C+ C PG W +PCQCN A C+ TG C+ C+ Sbjct: 850 QCD------------------RCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTM 891 Query: 187 GRRCSFRC--NCHGSPCEQDSGRCACRPGWWGPECQQQC--ECVRGRCSAASGECTCPPG 242 G C RC +G P C P GP+ +Q C + + C C PG Sbjct: 892 GHNCE-RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLA-CVCDPG 949 Query: 243 FRGARCELPCPAGSHG--VQCAHSCGRCK-HN-------EPCSPDTGSCESCEPGWNGTQ 292 + G+RC+ C +G G + SC C+ HN E C +TG C C G Sbjct: 950 YIGSRCD-DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008 Query: 293 CQQPCLPGTFGESCEQQC------------PHCRHGEA-CEPDTGHCQRCDPGWLGPRCE 339 CQ C G +G++ +Q C HC + C+ TG C C P +G C Sbjct: 1009 CQF-CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQC-LCLPNVIGQNC- 1065 Query: 340 DPCPTGTFGEDCGSTCPTC-------VQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGN 392 D C T+ G+ C C SC+ TG C C G+ G +C + C F G+ Sbjct: 1066 DRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTC-SECQELFWGD 1124 Query: 393 ---NCSVPCEC-PEGL----CHPVSGSC 412 C C+C P G+ C +G C Sbjct: 1125 PDVECRA-CDCDPRGIETPQCDQSTGQC 1151 Score = 115 bits (287), Expect = 2e-25 Identities = 116/440 (26%), Positives = 156/440 (35%), Gaps = 111/440 (25%) Query: 21 ELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIP--ICEGPDACQKDEVCVK------- 71 E DP+G V + QC + P GP C+ E ++ Sbjct: 774 ECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFC 833 Query: 72 ---PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG-QCEPATGAC-QCQADRWG 126 G C C G + C PG + P C + C C+ H C+P TG C CQ G Sbjct: 834 NPVTGQCHCFQGVYARQCDRCLPGHWGFPSC-QPCQCNGHADDCDPVTGECLNCQDYTMG 892 Query: 127 ARCE--------------------FPCACGP-HGR-----C--DPAT--GVCHCEPGWWS 156 CE PC GP GR C DP T C C+PG+ Sbjct: 893 HNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIG 952 Query: 157 STCR-----------------RPCQCN-----TAAARCEQATGACV-CKPGWWGRRCSF- 192 S C +PCQC+ T C++ TG C+ C G C F Sbjct: 953 SRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFC 1012 Query: 193 RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCELPC 252 R +G +QD +C C + Q+ C +C A+G+C C P G C+ Sbjct: 1013 RFGYYGDALQQDCRKCVCN---YLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCD--- 1066 Query: 253 PAGSHGVQCAHSCGRCKHNEPCSP-DTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCP 311 +CA + + C P + + S P N Q C+PG G +C + Sbjct: 1067 -------RCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE--- 1116 Query: 312 HCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCV 371 C+ +PD C+ CD PR G P C D TG CV Sbjct: 1117 -CQELFWGDPDV-ECRACD---CDPR--------------GIETPQC-----DQSTGQCV 1152 Query: 372 CSAGYWGPSCNASCPAGFHG 391 C G GP C+ C G+ G Sbjct: 1153 CVEGVEGPRCD-KCTRGYSG 1171 Score = 88.2 bits (217), Expect = 3e-17 Identities = 77/252 (30%), Positives = 98/252 (38%), Gaps = 54/252 (21%) Query: 194 CNCH-----GSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARC 248 C C S C+ + G+C CRP G C + C PG G Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-----------------CAPGTFGFG- 814 Query: 249 ELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQ 308 P+G +C H G N C+P TG C C G QC + CLPG +G Q Sbjct: 815 ----PSGCKPCEC-HLQGSV--NAFCNPVTGQCH-CFQGVYARQCDR-CLPGHWGFPSCQ 865 Query: 309 QCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGE------DCGSTCPTCVQG- 361 C H + C+P TG C C +G CE C G +G+ D CP C G Sbjct: 866 PCQCNGHADDCDPVTGECLNCQDYTMGHNCE-RCLAGYYGDPIIGSGDHCRPCP-CPDGP 923 Query: 362 --------SC--DTVTGD--CVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVS 409 SC D VT CVC GY G C+ C +G+ GN V C CH Sbjct: 924 DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD-DCASGYFGNPSEVGGSCQPCQCHNNI 982 Query: 410 GSCQPGSGSRDT 421 + P + ++T Sbjct: 983 DTTDPEACDKET 994 Score = 50.8 bits (120), Expect = 5e-06 Identities = 78/321 (24%), Positives = 105/321 (32%), Gaps = 85/321 (26%) Query: 100 RESCPCHPHG-QCEPATGA-----------CQCQADRWGARCEFPCACGPH--------G 139 R +C C+ H +C P G C C+ + G CE C H G Sbjct: 268 RGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCEL-CMDFYHDLPWRPAEG 326 Query: 140 RCDPATGVCHCEP---------------GWWSSTCRRPCQCNTAAARCEQATGACVCKPG 184 R A C+C G S CQ NT CEQ CKP Sbjct: 327 RNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQ------CKPF 380 Query: 185 WWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAA-SGECTCPPGF 243 ++ R + CE RC C P G + + C+ + +G+C C Sbjct: 381 YYQH--PERDIRDPNFCE----RCTCDPA--GSQNEGICDSYTDFSTGLIAGQCRCKLNV 432 Query: 244 RGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFG 303 G C++ C G + + S D C+SC GT +PG G Sbjct: 433 EGEHCDV-CKEGFYDLS--------------SEDPFGCKSCACNPLGT------IPG--G 469 Query: 304 ESCEQQCPHCRHGEACEPDTG-HCQRCDPGWLGPRCE-DPCPTGTFGEDCGSTCPTCVQG 361 C+ + HC TG HC +C P G + D C C + Sbjct: 470 NPCDSETGHCYCKRLV---TGQHCDQCLPEHWGLSNDLDGC------RPCDCDLGGALNN 520 Query: 362 SCDTVTGDCVCSAGYWGPSCN 382 SC +G C C G CN Sbjct: 521 SCFAESGQCSCRPHMIGRQCN 541 Score = 50.4 bits (119), Expect = 7e-06 Identities = 50/221 (22%), Positives = 73/221 (33%), Gaps = 79/221 (35%) Query: 70 VKPGLCR-CKPGFFGAHCSSRCPGQYWGP--DCR-----ESCPCHPHGQ-----CEPAT- 115 V G+C C+ G +C P Y P D R E C C P G C+ T Sbjct: 357 VSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTD 416 Query: 116 -------GACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTA 168 G C+C+ + G C+ C+ G++ + P C + Sbjct: 417 FSTGLIAGQCRCKLNVEGEHCDV------------------CKEGFYDLSSEDPFGCKS- 457 Query: 169 AARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQ------- 221 C C P G+PC+ ++G C C+ G C Q Sbjct: 458 ----------CACNP--------LGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWG 499 Query: 222 ---------QCEC-----VRGRCSAASGECTCPPGFRGARC 248 C+C + C A SG+C+C P G +C Sbjct: 500 LSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540 Score = 48.9 bits (115), Expect = 2e-05 Identities = 57/237 (24%), Positives = 73/237 (30%), Gaps = 62/237 (26%) Query: 235 GECTCPPGFRGARCELPC---------PAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCE 285 G C C +G CEL PA C +H+ C D + Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDM-AVYLAT 354 Query: 286 PGWNGTQCQQPCLPGTFGESCEQQCP-HCRHGEACEPDTGHCQRCDPGWLGPRCEDPCP- 343 +G C C T G +CEQ P + +H E D C+RC G + E C Sbjct: 355 GNVSGGVCDD-CQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDS 413 Query: 344 -----TGTFGEDC-------GSTCPTCVQG---------------------------SCD 364 TG C G C C +G CD Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473 Query: 365 TVTGDCVCSAGYWGPSCNASCPAGFHGNN----CSVPCECPEG-----LCHPVSGSC 412 + TG C C G C+ P + +N C PC+C G C SG C Sbjct: 474 SETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCR-PCDCDLGGALNNSCFAESGQC 529 >gi|153946395 tenascin C precursor [Homo sapiens] Length = 2201 Score = 141 bits (356), Expect = 2e-33 Identities = 115/355 (32%), Positives = 148/355 (41%), Gaps = 86/355 (24%) Query: 50 QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSS-RCPGQYWGPDCRESCPCHPH 108 ++C P C P AC C + G C C GF G CS RCP CH Sbjct: 339 EDCGKPTC--PHACHTQGRC-EEGQCVCDEGFAGVDCSEKRCPAD-----------CHNR 384 Query: 109 GQCEPATGACQCQADRWGARC---EFPCACGPHGRCDPATGVCHCEPGWWSSTC---RRP 162 G+C G C+C GA C + P C HGRC G C C+ G+ C R P Sbjct: 385 GRC--VDGRCECDDGFTGADCGELKCPNGCSGHGRC--VNGQCVCDEGYTGEDCSQLRCP 440 Query: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFR-----CNCHGSPCEQDSGRCACRPGWWGP 217 C++ RC + G CVC+ G+ G CS C+ HG +G C C G+ G Sbjct: 441 NDCHSRG-RCVE--GKCVCEQGFKGYDCSDMSCPNDCHQHGRCV---NGMCVCDDGYTGE 494 Query: 218 ECQ-QQC--ECV-RGRCSAASGECTCPPGFRGARC-ELPCPAGSHGVQCAHSCGRCKHNE 272 +C+ +QC +C RG C G+C C GF G C EL CP HG GRC + Sbjct: 495 DCRDRQCPRDCSNRGLC--VDGQCVCEDGFTGPDCAELSCPNDCHGQ------GRCVN-- 544 Query: 273 PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPG 332 G C C G+ G C+ EQ+CP HG+ RC G Sbjct: 545 ------GQC-VCHEGFMGKDCK------------EQRCPSDCHGQG---------RCVDG 576 Query: 333 WLGPRCEDPCPTGTFGEDCGS-TCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCP 386 + C G G DCG +CP+ V+G C+C+ GY G C+ P Sbjct: 577 ------QCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSP 625 Score = 138 bits (347), Expect = 2e-32 Identities = 129/421 (30%), Positives = 152/421 (36%), Gaps = 102/421 (24%) Query: 41 CCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSS-RCPGQYWGPDC 99 C GW K C+ P C P C C+ G C C GF G CS CP Sbjct: 176 CEPGW--KGPNCSEPEC--PGNCHLRGRCID-GQCICDDGFTGEDCSQLACPSD------ 224 Query: 100 RESCPCHPHGQCEPATGACQCQADRWGARCE-----FPCACGPHGRCDPATGVCHCEPGW 154 C+ G+C G C C GA C PC+ HG C G+C C G+ Sbjct: 225 -----CNDQGKC--VNGVCICFEGYAGADCSREICPVPCS-EEHGTC--VDGLCVCHDGF 274 Query: 155 WSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQD---SGRCACR 211 C +P N R CVC G+ G CS C ++ +G C C Sbjct: 275 AGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCS-ELICPNDCFDRGRCINGTCYCE 333 Query: 212 PGWWG-----PECQQQCECVRGRCSAASGECTCPPGFRGARC-ELPCPAGSHGVQCAHSC 265 G+ G P C C +GRC G+C C GF G C E CPA H+ Sbjct: 334 EGFTGEDCGKPTCPHACH-TQGRCE--EGQCVCDEGFAGVDCSEKRCPAD------CHNR 384 Query: 266 GRCKHNEPCSPDTGSCESCEPGWNGTQC------------------QQPCLPGTFGESCE 307 GRC G CE C+ G+ G C Q C G GE C Sbjct: 385 GRCV--------DGRCE-CDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS 435 Query: 308 Q-QCPHCRH--GEACEPDTGHCQRCDPGWLGPRCED------------------PCPTGT 346 Q +CP+ H G E G C C+ G+ G C D C G Sbjct: 436 QLRCPNDCHSRGRCVE---GKCV-CEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGY 491 Query: 347 FGEDC-GSTCPTCVQGSCDTVTGDCVCSAGYWGPSC-NASCPAGFHGNNCSV--PCECPE 402 GEDC CP V G CVC G+ GP C SCP HG V C C E Sbjct: 492 TGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHE 551 Query: 403 G 403 G Sbjct: 552 G 552 Score = 114 bits (286), Expect = 3e-25 Identities = 105/344 (30%), Positives = 121/344 (35%), Gaps = 76/344 (22%) Query: 110 QCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAA 169 QC G C A R + C G C CEPGW C P Sbjct: 139 QCTAGAGCCLQPAT---GRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCH 195 Query: 170 ARCEQATGACVCKPGWWGRRCS-----FRCNCHGSPCEQDSGRCACRPGWWGPECQQQ-- 222 R G C+C G+ G CS CN G +G C C G+ G +C ++ Sbjct: 196 LRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCV---NGVCICFEGYAGADCSREIC 252 Query: 223 ---CECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSC---GRCKHN----- 271 C G C G C C GF G C P C ++C GRC N Sbjct: 253 PVPCSEEHGTC--VDGLCVCHDGFAGDDCNKPL--------CLNNCYNRGRCVENECVCD 302 Query: 272 -----EPCSP--------DTGSCES----CEPGWNGTQCQQPCLP---GTFGESCEQQCP 311 E CS D G C + CE G+ G C +P P T G E QC Sbjct: 303 EGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCV 362 Query: 312 HCRHGEA--------CEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGS-TCPTCVQGS 362 C G A C D + RC G RCE C G G DCG CP G Sbjct: 363 -CDEGFAGVDCSEKRCPADCHNRGRCVDG----RCE--CDDGFTGADCGELKCPNGCSGH 415 Query: 363 CDTVTGDCVCSAGYWGPSCN-ASCPAGFHGNNCSVPCECPEGLC 405 V G CVC GY G C+ CP N+C C EG C Sbjct: 416 GRCVNGQCVCDEGYTGEDCSQLRCP-----NDCHSRGRCVEGKC 454 >gi|21264602 laminin alpha 5 [Homo sapiens] Length = 3695 Score = 139 bits (350), Expect = 1e-32 Identities = 121/412 (29%), Positives = 165/412 (40%), Gaps = 105/412 (25%) Query: 51 ECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG- 109 +C+ +G +AC+KD + G C CKP F G HC PG ++GP C + C C G Sbjct: 495 DCSAAGTQG-NACRKDP---RVGRCLCKPNFQGTHCELCAPG-FYGPGC-QPCQCSSPGV 548 Query: 110 ---QCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCN 166 +C+P TG C+C+ GA C+ C P P +C C P Sbjct: 549 ADDRCDPDTGQCRCRVGFEGATCD---RCAPGYFHFPLCQLCGCSP------------AG 593 Query: 167 TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG-PECQQQCEC 225 T C++A G C+C+P + G C CRPG+ G P C Q C C Sbjct: 594 TLPEGCDEA-GRCLCQPEFAGPHCD-----------------RCRPGYHGFPNC-QACTC 634 Query: 226 -VRG---RCSAASGECTCPPGFRGARCELPCPAGSHG----VQCAHSCGRCKHNEPCSPD 277 RG + A G C C PG+ G C+ C G HG V C H + C P Sbjct: 635 DPRGALDQLCGAGGLCRCRPGYTGTACQ-ECSPGFHGFPSCVPC-HCSAEGSLHAACDPR 692 Query: 278 TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEP---------------- 321 +G C SC P G +C C+PG + P+C G +C P Sbjct: 693 SGQC-SCRPRVTGLRC-DTCVPGAY------NFPYCEAG-SCHPAGLAPVDPALPEAQVP 743 Query: 322 -------DTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS------CDTVTG 368 + C RC PG+ G +P E C + C ++G+ C TG Sbjct: 744 CMCRAHVEGPSCDRCKPGFWGLSPSNP-------EGC-TRCSCDLRGTLGGVAECQPGTG 795 Query: 369 DCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCH---PVSGSCQPGSG 417 C C G +C ASC GF G + + C C + SC+P +G Sbjct: 796 QCFCKPHVCGQAC-ASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTG 846 Score = 132 bits (331), Expect = 2e-30 Identities = 130/428 (30%), Positives = 161/428 (37%), Gaps = 106/428 (24%) Query: 73 GLC-RCKPGFFGAHCSSRCPGQYWGPD--------CRESCPCHPH---GQCEPATGACQC 120 G+C C+ G +C PG Y P+ CR C C G CE TG C C Sbjct: 391 GVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRR-CNCESDFTDGTCEDLTGRCYC 449 Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRP----------CQCNTA-- 168 + + G RC+ CA G TG C P SS R C C+ A Sbjct: 450 RPNFSGERCDV-CAEG-------FTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGT 501 Query: 169 ---AARCEQATGACVCKPGWWGRRCSF-----------RCNCHGSP------CEQDSGRC 208 A R + G C+CKP + G C C C SP C+ D+G+C Sbjct: 502 QGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQPCQC-SSPGVADDRCDPDTGQC 560 Query: 209 ACRPGWWGPECQQQCE-------CVRGRCSAA---------SGECTCPPGFRGARCELPC 252 CR G+ G C + C CS A +G C C P F G C+ C Sbjct: 561 RCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDR-C 619 Query: 253 PAGSHGVQCAHSCG---RCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQ 309 G HG +C R ++ C G C C PG+ GT CQ+ C PG G Sbjct: 620 RPGYHGFPNCQACTCDPRGALDQLCGAG-GLCR-CRPGYTGTACQE-CSPGFHGFPSCVP 676 Query: 310 CPHCRHGE---ACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTV 366 C G AC+P +G C C P G RC D C G + P C GSC Sbjct: 677 CHCSAEGSLHAACDPRSGQCS-CRPRVTGLRC-DTCVPGAYN------FPYCEAGSCHPA 728 Query: 367 ------------TGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCH---PVSG- 410 C+C A GPSC+ C GF G + S P C C + G Sbjct: 729 GLAPVDPALPEAQVPCMCRAHVEGPSCD-RCKPGFWGLSPSNPEGCTRCSCDLRGTLGGV 787 Query: 411 -SCQPGSG 417 CQPG+G Sbjct: 788 AECQPGTG 795 Score = 127 bits (320), Expect = 3e-29 Identities = 118/421 (28%), Positives = 151/421 (35%), Gaps = 116/421 (27%) Query: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDC----------RE---------SCPCHPHG---- 109 G C C+P F G C G P C RE +C C G Sbjct: 445 GRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGN 504 Query: 110 --QCEPATGACQCQADRWGARCEF-----------PCACGPHG----RCDPATGVCHCEP 152 + +P G C C+ + G CE PC C G RCDP TG C C Sbjct: 505 ACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRV 564 Query: 153 GWWSSTCRRP------------CQCNTAAAR---CEQATGACVCKPGWWGRRCSFRC--- 194 G+ +TC R C C+ A C++A G C+C+P + G C RC Sbjct: 565 GFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCDEA-GRCLCQPEFAGPHCD-RCRPG 622 Query: 195 -----NCHGSPCEQDS---------GRCACRPGWWGPECQQ------------QCEC--- 225 NC C+ G C CRPG+ G CQ+ C C Sbjct: 623 YHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAE 682 Query: 226 --VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQC-AHSC--GRCKHNEPCSPDTGS 280 + C SG+C+C P G RC+ P + C A SC +P P+ Sbjct: 683 GSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQV 742 Query: 281 CESCEPGWNGTQCQQPCLPGTFG--ESCEQQCPHCR-------HGEA-CEPDTGHCQRCD 330 C G C + C PG +G S + C C G A C+P TG C C Sbjct: 743 PCMCRAHVEGPSCDR-CKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF-CK 800 Query: 331 PGWLGPRCEDPCPTGTFGEDCGST--CPTC-------VQGSCDTVTGDCVCSAGYWGPSC 381 P G C C G FG D C +C + SC+ TG C C GP+C Sbjct: 801 PHVCGQACAS-CKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859 Query: 382 N 382 + Sbjct: 860 S 860 Score = 124 bits (312), Expect = 3e-28 Identities = 113/358 (31%), Positives = 137/358 (38%), Gaps = 77/358 (21%) Query: 90 CPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHG-RCDPATGVC 148 CP Y G C+E P G + + RC PC C H RC P +GVC Sbjct: 1833 CPASYRGDSCQECAP-----------GFYRDVKGLFLGRC-VPCQCHGHSDRCLPGSGVC 1880 Query: 149 HCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRC 208 CQ NT A CE+ C+ G+ R C PC Sbjct: 1881 V------------DCQHNTEGAHCER------CQAGFVSSRDDPSAPCVSCPCPLSVPSN 1922 Query: 209 ACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHG--VQCAHSCG 266 G C GR +C C PG+ GA CE C G G + SC Sbjct: 1923 NFAEG---------CVLRGGRT-----QCLCKPGYAGASCER-CAPGFFGNPLVLGSSCQ 1967 Query: 267 RCK---HNEP------CSPDTGSCESCEPGWNGTQCQQPCLPGTFGESC-EQQCPHCR-- 314 C + +P C P TG+C C G +C+ C PG +G + C C Sbjct: 1968 PCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTRCDCT 2026 Query: 315 --HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGED-CGS----TCPTCVQGS-CDTV 366 EAC+P +GHC C G G RC D C G FG D CG C +GS C Sbjct: 2027 PCGTEACDPHSGHCL-CKAGVTGRRC-DRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQ 2084 Query: 367 TGDCVCSAGYWGPSCNASCPA--GFHGNNCSVPCECPEGLCHPVSG--SCQPG-SGSR 419 +G C C G GP C P G C C+CP G C P +G +C PG SG R Sbjct: 2085 SGQCHCRPGTMGPQCRECAPGYWGLPEQGCR-RCQCPGGRCDPHTGRCNCPPGLSGER 2141 Score = 122 bits (306), Expect = 1e-27 Identities = 97/312 (31%), Positives = 124/312 (39%), Gaps = 86/312 (27%) Query: 26 GQHVCVASSPSAE----LQCCAGWRQKDQECTIPI--CEGPDACQKD---EVCVKPG--- 73 G VCV + E +C AG+ + + P C P + + E CV G Sbjct: 1876 GSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRT 1935 Query: 74 LCRCKPGFFGAHCSSRCPGQYWGP-----DCRESCPCHPHGQ-------CEPATGACQ-C 120 C CKPG+ GA C PG + P C + C C +G C+P TGAC+ C Sbjct: 1936 QCLCKPGYAGASCERCAPGFFGNPLVLGSSC-QPCDCSGNGDPNLLFSDCDPLTGACRGC 1994 Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAAR-CEQATGAC 179 G RCE CA G +G PG C R C C C+ +G C Sbjct: 1995 LRHTTGPRCEI-CAPGFYGNA--------LLPG----NCTR-CDCTPCGTEACDPHSGHC 2040 Query: 180 VCKPGWWGRRCSFRCN--------------------CHGSPCEQDSGRCACRPGWWGPEC 219 +CK G GRRC RC GS C SG+C CRPG GP+C Sbjct: 2041 LCKAGVTGRRCD-RCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQC 2099 Query: 220 QQ--------------QCECVRGRCSAASGECTCPPGFRGARC-------ELPCPAG--S 256 ++ +C+C GRC +G C CPPG G RC ++P P G Sbjct: 2100 RECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVG 2159 Query: 257 HGVQCAHSCGRC 268 H + C C C Sbjct: 2160 HSIHC-EVCDHC 2170 Score = 116 bits (291), Expect = 7e-26 Identities = 102/343 (29%), Positives = 127/343 (37%), Gaps = 63/343 (18%) Query: 74 LCRCKPGFFGAHCSSRCPGQYW---GPDCRESCPCHPHG---QCEPATGAC-QCQADRWG 126 LC C + G C PG Y G PC HG +C P +G C CQ + G Sbjct: 1830 LCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEG 1889 Query: 127 ARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGA--CVCKPG 184 A CE A R DP+ C C N A C G C+CKPG Sbjct: 1890 AHCERCQAGFVSSRDDPSAPCVSCP-------CPLSVPSNNFAEGCVLRGGRTQCLCKPG 1942 Query: 185 WWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG------PECQQQCEC--------VRGRC 230 + G C C PG++G CQ C+C + C Sbjct: 1943 YAGASCE-----------------RCAPGFFGNPLVLGSSCQP-CDCSGNGDPNLLFSDC 1984 Query: 231 SAASGECT-CPPGFRGARCELPCPAGSHGVQCAHSCGRCK----HNEPCSPDTGSCESCE 285 +G C C G RCE+ P +C RC E C P +G C C+ Sbjct: 1985 DPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHC-LCK 2043 Query: 286 PGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA-----CEPDTGHCQRCDPGWLGPRCED 340 G G +C + C G FG C C G A C P +G C C PG +GP+C + Sbjct: 2044 AGVTGRRCDR-CQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCH-CRPGTMGPQCRE 2101 Query: 341 PCPTGTFG-EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCN 382 C G +G + G C G CD TG C C G G C+ Sbjct: 2102 -CAPGYWGLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCD 2143 Score = 106 bits (264), Expect = 1e-22 Identities = 95/329 (28%), Positives = 121/329 (36%), Gaps = 61/329 (18%) Query: 16 GTQGSELDPK-GQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGL 74 G DP GQ C A CA C + C A E C + G Sbjct: 547 GVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQL--CGCSPAGTLPEGCDEAGR 604 Query: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGA---CQCQADRWGARCE- 130 C C+P F G HC PG + P+C ++C C P G + GA C+C+ G C+ Sbjct: 605 CLCQPEFAGPHCDRCRPGYHGFPNC-QACTCDPRGALDQLCGAGGLCRCRPGYTGTACQE 663 Query: 131 -----------FPCACGP----HGRCDPATGVCHCEP---GWWSSTCRRPCQCN---TAA 169 PC C H CDP +G C C P G TC P N A Sbjct: 664 CSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTC-VPGAYNFPYCEA 722 Query: 170 ARCEQATGACVCKPGWWGRRCSFRCNCH--GSPCEQDSGRCACRPGWWG-----PECQQQ 222 C A G P + C H G C++ C+PG+WG PE + Sbjct: 723 GSCHPA-GLAPVDPALPEAQVPCMCRAHVEGPSCDR------CKPGFWGLSPSNPEGCTR 775 Query: 223 CEC-VRG------RCSAASGECTCPPGFRGARCELPCPAGSHGVQCA--HSCGRCKHN-- 271 C C +RG C +G+C C P G C C G G+ A C C+ + Sbjct: 776 CSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC-ASCKDGFFGLDQADYFGCRSCRCDIG 834 Query: 272 ----EPCSPDTGSCESCEPGWNGTQCQQP 296 + C P TG C C P G C +P Sbjct: 835 GALGQSCEPRTGVCR-CRPNTQGPTCSEP 862 Score = 90.5 bits (223), Expect = 6e-18 Identities = 79/265 (29%), Positives = 102/265 (38%), Gaps = 62/265 (23%) Query: 161 RPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG-PEC 219 RPC C+ A TG C+P +C CH +D RCA G+WG P C Sbjct: 1436 RPCGCHEVGA-----TGP-TCEP------FGGQCPCHAHVIGRDCSRCAT--GYWGFPNC 1481 Query: 220 QQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTG 279 + C+C C +G+C CPP C L C + G C P G Sbjct: 1482 RP-CDCGARLCDELTGQCICPPRTIPPDCLL-CQPQTFG---------------CHPLVG 1524 Query: 280 SCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPD-TGH-CQRCDPGWLG-P 336 CE C C P + +C+ C+ C P+ TG C C PG+ G P Sbjct: 1525 -CEECN-------CSGPGIQELTDPTCDTDSGQCK----CRPNVTGRRCDTCSPGFHGYP 1572 Query: 337 RCEDPCPTGTFGEDC--GSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNC 394 RC PC DC T P G CD +TG C C GP C+ C G + Sbjct: 1573 RCR-PC-------DCHEAGTAP----GVCDPLTGQCYCKENVQGPKCD-QCSLGTFSLDA 1619 Query: 395 SVPCECPEGLCHPVSGSCQPGSGSR 419 + P C C + C+ S +R Sbjct: 1620 ANPKGCTRCFCFGATERCRSSSYTR 1644 Score = 88.6 bits (218), Expect = 2e-17 Identities = 105/404 (25%), Positives = 137/404 (33%), Gaps = 102/404 (25%) Query: 103 CPCHPHGQC-------EPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWW 155 C CH H +P C CQ + G C+ RC P +P Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCD---------RCCPGFNQQPWKPATA 350 Query: 156 SSTCR-RPCQCNTAAARC------EQATGACVCKPGWWGRRCSFRCNCH--GSPCEQDSG 206 +S + C C A C ++ + + G C H G CE+ Sbjct: 351 NSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCER--- 407 Query: 207 RCACRPGWW--------GPECQQQCEC----VRGRCSAASGECTCPPGFRGARCELPCPA 254 C PG++ P ++C C G C +G C C P F G RC++ C Sbjct: 408 ---CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDV-CAE 463 Query: 255 GSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCR 314 G G C S DT E P C GT G +C + R Sbjct: 464 GFTGFPS------CYPTPSSSNDTR--EQVLPAGQIVNCDCSAA-GTQGNACRKDP---R 511 Query: 315 HGEA-CEPDTG--HCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCV 371 G C+P+ HC+ C PG+ GP C+ PC C S P CD TG C Sbjct: 512 VGRCLCKPNFQGTHCELCAPGFYGPGCQ-PC-------QCSS--PGVADDRCDPDTGQCR 561 Query: 372 CSAGYWGPSCNASCPAGFHGNNCSVPCEC------PEG-------LCHPVSGS-----CQ 413 C G+ G +C+ P FH C + C C PEG LC P C+ Sbjct: 562 CRVGFEGATCDRCAPGYFHFPLCQL-CGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCR 620 Query: 414 PG--------------SGSRDTALIAGSLVPLLLLFLGLACCAC 443 PG G+ D AG L + G AC C Sbjct: 621 PGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQEC 664 Score = 76.3 bits (186), Expect = 1e-13 Identities = 59/205 (28%), Positives = 75/205 (36%), Gaps = 40/205 (19%) Query: 73 GLCRCKPGFFGAHCSSRCPGQYW-GPDCRESCPCHPHGQCEPATGACQCQADRWGARCEF 131 G C C G CS RC YW P+CR C C C+ TG C C C Sbjct: 1455 GQCPCHAHVIGRDCS-RCATGYWGFPNCR-PCDCGAR-LCDELTGQCICPPRTIPPDCLL 1511 Query: 132 PCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191 C P T CH G C P C+ +G C C+P GRRC Sbjct: 1512 ---------CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCD 1562 Query: 192 FRCNCHGSPCEQDSGRCACRPGWWG-PECQQQCEC-----VRGRCSAASGECTCPPGFRG 245 C PG+ G P C + C+C G C +G+C C +G Sbjct: 1563 -----------------TCSPGFHGYPRC-RPCDCHEAGTAPGVCDPLTGQCYCKENVQG 1604 Query: 246 ARCELPCPAGSHGVQCAH--SCGRC 268 +C+ C G+ + A+ C RC Sbjct: 1605 PKCD-QCSLGTFSLDAANPKGCTRC 1628 Score = 66.6 bits (161), Expect = 9e-11 Identities = 68/279 (24%), Positives = 85/279 (30%), Gaps = 96/279 (34%) Query: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLC 75 GT D G+ +C C C C+ A D++C GLC Sbjct: 593 GTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGAL--DQLCGAGGLC 650 Query: 76 RCKPGFFGAHCSSRCPGQYWGPDC------------------RESCPCHPH--------- 108 RC+PG+ G C PG + P C C C P Sbjct: 651 RCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTC 710 Query: 109 ------------GQCEPATGA------------CQCQA-------DR-----WGARCEFP 132 G C PA A C C+A DR WG P Sbjct: 711 VPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNP 770 Query: 133 -----CACGPHG------RCDPATGVCHCEP---GWWSSTCR--------------RPCQ 164 C+C G C P TG C C+P G ++C+ R C+ Sbjct: 771 EGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCR 830 Query: 165 CNTAAA---RCEQATGACVCKPGWWGRRCSFRCNCHGSP 200 C+ A CE TG C C+P G CS H P Sbjct: 831 CDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLP 869 Score = 56.2 bits (134), Expect = 1e-07 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 11/93 (11%) Query: 50 QECTIPICEGPDACQ-KDEVC-VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHP 107 +EC C GP + D C G C+C+P G C + PG + P CR C CH Sbjct: 1526 EECN---CSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCR-PCDCHE 1581 Query: 108 HGQ----CEPATGACQCQADRWGARCEFPCACG 136 G C+P TG C C+ + G +C+ C+ G Sbjct: 1582 AGTAPGVCDPLTGQCYCKENVQGPKCD-QCSLG 1613 >gi|148833508 notch1 preproprotein [Homo sapiens] Length = 2555 Score = 137 bits (344), Expect = 5e-32 Identities = 130/509 (25%), Positives = 172/509 (33%), Gaps = 135/509 (26%) Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC---VKPGLCRCKPGFFGAHC 86 C+ + S E QC G+ E + C + CQ D C + C C PG+ G HC Sbjct: 429 CINTLGSFECQCLQGYTGPRCEIDVNECVS-NPCQNDATCLDQIGEFQCICMPGYEGVHC 487 Query: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCEF--------PCACG 136 +C S PC +G+C C+C G C++ PC G Sbjct: 488 EVNTD------ECASS-PCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNG 540 Query: 137 PHGRCDPATGVCHCEPGWWSSTCR------RPCQCNTAAARCEQATGACVCKPGWWGRRC 190 P T C C G+ + C P C+ + + AT C+C+PG+ G C Sbjct: 541 AKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHC 600 Query: 191 SFRCN-CHGSPCE-----QDSGR---CACRPGWWGPECQQQC-ECVRGRCSAAS------ 234 N C PC QD C C G GP C+ +C C + + Sbjct: 601 ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID 660 Query: 235 -GECTCPPGFRGARCEL-------------------------PCPAGSHGVQCAHSCGRC 268 EC C PG+ G+ C + CP G H C C Sbjct: 661 GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC 720 Query: 269 KHNEPCSPDTGSCE--------SCEPGWNGTQC--------QQPCL-------------- 298 N PC G+C C+PGW+GT C PC+ Sbjct: 721 NSN-PCV--HGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVC 777 Query: 299 ---PGTFGESCEQQCPHC------RHGEACEPDTGHCQRCDPGWLGPRCE--------DP 341 G G +C+ C G + G+ C + G CE P Sbjct: 778 TCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSP 837 Query: 342 CPTG---TFGEDCGS---TCPTCVQG-SCDTVTGDCVCSAGYWGPSC-------NASCPA 387 C G ED S CPT QG +C+ +CV S G SC C A Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQA 897 Query: 388 GFHGNNCSVPC-ECPEGLCHPVSGSCQPG 415 G+ G NC +C CH GSC G Sbjct: 898 GYSGRNCETDIDDCRPNPCHN-GGSCTDG 925 Score = 124 bits (312), Expect = 3e-28 Identities = 115/411 (27%), Positives = 150/411 (36%), Gaps = 111/411 (27%) Query: 96 GPDCRESCP-CHPHGQCEPATG--ACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEP 152 GP C + C G+CE A G AC C G RC+ P C Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPC----------------- 63 Query: 153 GWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCN--CHGSPCEQDSG---- 206 S+ C+ C+ R A AC C G+ G C + C +PC Sbjct: 64 --LSTPCKNAGTCHVVDRR-GVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLL 120 Query: 207 -----RCACRPGWWGPECQQQCECVRGRCS--------AASGECTCPPGFRGARCELPCP 253 +C C PGW G CQQ C C+ AS C CPP F G C Sbjct: 121 TLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVN 180 Query: 254 AGSHGVQCAHSCGRCKHNEPCSPDTGSCES-CEPGWNGTQCQQP---------------- 296 +C G C+H C + GS C G C++P Sbjct: 181 ------ECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCR 234 Query: 297 ----------CLPGTFGESCEQ---QCP--HCRHGEACEP--DTGHCQRCDPGWLGPRCE 339 CLPG G++CE+ CP +C++G AC +T +C RC P W G C Sbjct: 235 PTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNC-RCPPEWTGQYCT 293 Query: 340 DPCPTGTFGEDCGSTCPTCVQ-GSCDTVTG--DCVCSAGYWGPSC-----NASCPAGFHG 391 + ++C C G+C G +CVC G+ G C + + A FHG Sbjct: 294 EDV------DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHG 347 Query: 392 NNC-----SVPCECPEG----LCH----PVSGSCQPGSGSRDTALIAGSLV 429 C S CECP G LCH +S C GS DT + G + Sbjct: 348 ATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNC-DTNPVNGKAI 397 Score = 122 bits (305), Expect = 2e-27 Identities = 129/465 (27%), Positives = 162/465 (34%), Gaps = 133/465 (28%) Query: 59 GPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRE-----SCPCHPHGQCE- 112 GP Q E C+ G C G C G + GP C++ S PC G C Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCG----GAFVGPRCQDPNPCLSTPCKNAGTCHV 76 Query: 113 -----PATGACQCQADRWGARCEFPC-------ACGPHGRCDPATGV---CHCEPGWWSS 157 A AC C G C P C G CD T C C PGW Sbjct: 77 VDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136 Query: 158 TCRR--PCQCNTAA--ARC--EQATGACVCKPGWWGRRCSFRCN-C--------HGSPCE 202 +C++ PC N A +C +A+ C C P + G C N C HG C Sbjct: 137 SCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCH 196 Query: 203 QDSG--RCACRPGWWGPECQQ------QCECVRGRCSAASG----ECTCPPGFRGARCEL 250 + G RC CR GP C++ C G +G EC C PGF G CE Sbjct: 197 NEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEE 256 Query: 251 ---PCPAGSHGVQCAHSCGRCKHNEPC--SPDTGSCESCEPGWNGTQCQQPCLPGTFGES 305 CP + CK+ C +T +C C P W G C + + Sbjct: 257 NIDDCPGNN-----------CKNGGACVDGVNTYNCR-CPPEWTGQYCTEDV------DE 298 Query: 306 CEQQCPHCRHGEACEPDTG--HCQRCDPGWLGPRCED----------------------- 340 C+ C++G C G +C C GW G C + Sbjct: 299 CQLMPNACQNGGTCHNTHGGYNCV-CVNGWTGEDCSENIDDCASAACFHGATCHDRVASF 357 Query: 341 --PCPTGTFGEDC--GSTCPT--CVQGS-CDT--VTGD--CVCSAGYWGPSCNA---SCP 386 CP G G C C + C +GS CDT V G C C +GY GP+C+ C Sbjct: 358 YCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECS 417 Query: 387 AGF----HGNNC-----SVPCECPEGLCHP---------VSGSCQ 413 G H C S C+C +G P VS CQ Sbjct: 418 LGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQ 462 Score = 121 bits (303), Expect = 3e-27 Identities = 129/478 (26%), Positives = 167/478 (34%), Gaps = 148/478 (30%) Query: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCEF- 131 C C PG+ G +C +C ES PC G C+ T C C+ G C+ Sbjct: 739 CDCDPGWSGTNCDIN------NNEC-ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTN 791 Query: 132 --PCACGP---HGRC--DPATGVCHCEPGWWSSTCR------RPCQCNTAAARCEQATG- 177 CA P G C D A C+C + +TC P C C Q+ Sbjct: 792 INECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGG-ECRQSEDY 850 Query: 178 ---ACVCKPGWWGRRCSFRCN------C-HGSPCEQDSG--RCACRPGWWGPECQQQCEC 225 +CVC GW G+ C N C HG+ C+ G RC C+ G+ G C+ + Sbjct: 851 ESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDD 910 Query: 226 VRGRCSAASGECT---------CPPGFRGARCE-------------------------LP 251 R G CT C PGFRG CE Sbjct: 911 CRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCT 970 Query: 252 CPAGSHGVQCAHSCGRCKHNEPCSPDTGSCES--------CEPGWNGTQCQ--------Q 295 CPAG G+ C ++ C E + G+C C PG+ G+ CQ Q Sbjct: 971 CPAGFSGIHCENNTPDC--TESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQ 1028 Query: 296 PCL-PGTFGESCEQ---QCPH------------------CRHGEAC-EPDTGHCQRCDPG 332 PCL GT + C CP C++G C + T + C G Sbjct: 1029 PCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSG 1088 Query: 333 WLGPRCEDP------------------CPTGTFGEDCGST----CPTCVQGS-CDTVTGD 369 W G C+ P C G D G+T C GS C+ + + Sbjct: 1089 WTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDE 1148 Query: 370 CVCSAGYWGPSC-------NASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRD 420 C S G +C + C AG+HG NCS E E L HP CQ G D Sbjct: 1149 CSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSE--EIDECLSHP----CQNGGTCLD 1200 Score = 111 bits (277), Expect = 3e-24 Identities = 116/442 (26%), Positives = 146/442 (33%), Gaps = 112/442 (25%) Query: 49 DQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSS-------------------- 88 D C C C D + + CRC PG+ G C Sbjct: 103 DNACLTNPCRNGGTC--DLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEA 160 Query: 89 ----RCPGQYWGPDCRESCP--------CHPHGQCEPATGA--CQCQADRWGARCE---F 131 CP + GP CR+ C G C G+ C C+A G CE Sbjct: 161 SYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYV 220 Query: 132 PCA---CGPHGRCDP---ATGVCHCEPGWWSSTCRRPC------QCNTAAARCEQA-TGA 178 PC+ C G C P T C C PG+ C C A + T Sbjct: 221 PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280 Query: 179 CVCKPGWWGRRCS---FRCNC------HGSPCEQDSG--RCACRPGWWGPECQQQC-ECV 226 C C P W G+ C+ C +G C G C C GW G +C + +C Sbjct: 281 CRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCA 340 Query: 227 RGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCE---- 282 C + TC CE CP G G+ C H C N PC+ + +C+ Sbjct: 341 SAACFHGA---TCHDRVASFYCE--CPHGRTGLLC-HLNDACISN-PCN-EGSNCDTNPV 392 Query: 283 ------SCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTG--HCQRCDPGWL 334 +C G+ G C Q + C C H C G CQ C G+ Sbjct: 393 NGKAICTCPSGYTGPACSQDV------DECSLGANPCEHAGKCINTLGSFECQ-CLQGYT 445 Query: 335 GPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGD--CVCSAGYWGPSCN------ASCP 386 GPRCE +C S P +C G+ C+C GY G C AS P Sbjct: 446 GPRCEIDV------NECVSN-PCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSP 498 Query: 387 AGFHGNNC-----SVPCECPEG 403 H C CECP G Sbjct: 499 C-LHNGRCLDKINEFQCECPTG 519 Score = 109 bits (272), Expect = 1e-23 Identities = 126/473 (26%), Positives = 152/473 (32%), Gaps = 114/473 (24%) Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDA-----CQKD--EVCVKPGLCRCKPGFF 82 C + P A C G + E + IC P + C++D E KPGLCR Sbjct: 138 CQQADPCASNPCANGGQCLPFEASY-ICHCPPSFHGPTCRQDVNECGQKPGLCR-----H 191 Query: 83 GAHCSSR-------CPGQYWGPDC-RESCPCHPH-----GQCEPA---TGACQCQADRWG 126 G C + C + GP+C R PC P G C P T C C G Sbjct: 192 GGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTG 251 Query: 127 ARCEFPCACGPHGRCDPA--------TGVCHCEPGWWSSTCRRP---CQCNTAAAR---- 171 CE P C T C C P W C CQ A + Sbjct: 252 QNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGT 311 Query: 172 CEQATGA--CVCKPGWWGRRCSFRCN-------CHGSPCEQD--SGRCACRPGWWGPECQ 220 C G CVC GW G CS + HG+ C S C C G G C Sbjct: 312 CHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCH 371 Query: 221 QQCECVRGRCSAASG----------ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKH 270 C+ C+ S CTCP G+ G C +C+ C+H Sbjct: 372 LNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVD------ECSLGANPCEH 425 Query: 271 NEPCSPDTGSCE-SCEPGWNGTQCQ---QPCL--PGTFGESCEQQ-------CPHCRHGE 317 C GS E C G+ G +C+ C+ P +C Q C G Sbjct: 426 AGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGV 485 Query: 318 ACEPDTGHCQRCDPGWLGPRCED-------PCPTGTFGEDCGSTCPTCVQGSCDT----- 365 CE +T C P RC D CPTG G C C C Sbjct: 486 HCEVNTDEC-ASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCL 544 Query: 366 ---VTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPG 415 T CVC+ GY G C EC CH GSC+ G Sbjct: 545 DGPNTYTCVCTEGYTGTHCEVDID------------ECDPDPCH--YGSCKDG 583 Score = 108 bits (269), Expect = 3e-23 Identities = 117/464 (25%), Positives = 154/464 (33%), Gaps = 120/464 (25%) Query: 41 CCAGWRQKDQECTIPICEGPDACQKDEVC---VKPGLCRCKPGFFGAHCSSRCPGQYWGP 97 C AG+ ++ E I C P+ C C + C C PGF G C Sbjct: 895 CQAGYSGRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEE--------- 944 Query: 98 DCRE--SCPCHPHGQCEPATGA--CQCQADRWGARCE------FPCACGPHGRCDPATG- 146 D E S PC C + C C A G CE +C G C Sbjct: 945 DINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINS 1004 Query: 147 -VCHCEPGWWSSTCRRPC-QCNTA----AARCEQATGA--CVCKPGWWGRRCSFRCN-CH 197 C C PG+ S C+ +C++ C+ G+ C C G+ G C + C Sbjct: 1005 FTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCD 1064 Query: 198 GSPCEQDSG--------RCACRPGWWGPEC---QQQCE-------------CVRGRCSAA 233 SPC+ RC C GW G C CE C G Sbjct: 1065 SSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVD 1124 Query: 234 SG---ECTCPPGFRGARCE-------------------------LPCPAGSHGVQCAHSC 265 +G C C G+ G+ CE C AG HGV C+ Sbjct: 1125 AGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1184 Query: 266 GRCKHNEPCS--------PDTGSCESCEPGWNGTQCQ---QPCLPGTFGESCEQQCPHCR 314 C + PC P+T C SC G G C+ C P S +C Sbjct: 1185 DECL-SHPCQNGGTCLDLPNTYKC-SCPRGTQGVHCEINVDDCNPPVDPVSRSPKC--FN 1240 Query: 315 HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGD--CVC 372 +G + G+ C PG++G RCE G E + C +C D C C Sbjct: 1241 NGTCVDQVGGYSCTCPPGFVGERCE-----GDVNECLSNPCDARGTQNCVQRVNDFHCEC 1295 Query: 373 SAGYWGPSCNA---SCPAG--FHGNNCSVP--------CECPEG 403 AG+ G C + C +G C+V C+CP G Sbjct: 1296 RAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAG 1339 Score = 107 bits (266), Expect = 6e-23 Identities = 122/478 (25%), Positives = 160/478 (33%), Gaps = 124/478 (25%) Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCV---KPGLCRCKPGFFGAHC 86 C S C AG+ E P C +C CV C C PGF G++C Sbjct: 960 CTDCVDSYTCTCPAGFSGIHCENNTPDCT-ESSCFNGGTCVDGINSFTCLCPPGFTGSYC 1018 Query: 87 SS-------------------------RCPGQYWGPDCR------ESCPCHPHGQC--EP 113 CP Y GP+C+ +S PC G+C Sbjct: 1019 QHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTH 1078 Query: 114 ATGACQCQADRWGARCEFPCA----------------CGPHGRCDPA--TGVCHCEPGWW 155 C+C + G C+ P C G C A T C C+ G+ Sbjct: 1079 TQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT 1138 Query: 156 SSTCR------RPCQCNTAAARCEQATG-ACVCKPGWWGRRCSFRCN-CHGSPCEQ---- 203 S C P C A + G +C C G+ G CS + C PC+ Sbjct: 1139 GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC 1198 Query: 204 ----DSGRCACRPGWWGPECQ--------------QQCECVR-GRCSAASG--ECTCPPG 242 ++ +C+C G G C+ + +C G C G CTCPPG Sbjct: 1199 LDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPG 1258 Query: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302 F G RCE C N PC D ++C N C+ C G Sbjct: 1259 FVGERCE-------------GDVNECLSN-PC--DARGTQNCVQRVNDFHCE--CRAGHT 1300 Query: 303 GESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS 362 G CE C+ G+ C+ + G C G C+ CP G G C + TC GS Sbjct: 1301 GRRCESVINGCK-GKPCK-NGGTCAVASNTARGFICK--CPAGFEGATCENDARTC--GS 1354 Query: 363 CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECP---------EGLCHPVSGS 411 + G C +G P+C C F G C P P +G C P S S Sbjct: 1355 LRCLNGG-TCISGPRSPTC--LCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSES 1409 Score = 62.4 bits (150), Expect = 2e-09 Identities = 77/308 (25%), Positives = 103/308 (33%), Gaps = 56/308 (18%) Query: 23 DPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC------VKPGLCR 76 D +G CV +C AG + E I C+G C+ C + +C+ Sbjct: 1277 DARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKG-KPCKNGGTCAVASNTARGFICK 1335 Query: 77 CKPGFFGAHCSSRCPGQYWGPDCRE--SCPCHPHGQC--EPATGACQCQADRWGARCEFP 132 C GF GA C + D R S C G C P + C C G C+FP Sbjct: 1336 CPAGFEGATCEN---------DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFP 1386 Query: 133 CA--------CGPHGRCDPATGV----CHCEPGWWSSTCR-RPCQCNTAAAR------CE 173 + C G C+P + C C + C A R E Sbjct: 1387 ASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIE 1446 Query: 174 QATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVR----GR 229 +A C+ + CS +CN H C D G C+ C Q +C + G Sbjct: 1447 EACELPECQEDAGNKVCSLQCNNHA--CGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGH 1504 Query: 230 CSAASGECTCP-PGFRGARCELPC-PAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPG 287 C + C GF R E C P + S G C D G C S E Sbjct: 1505 CDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHC--------DQG-CNSAECE 1555 Query: 288 WNGTQCQQ 295 W+G C + Sbjct: 1556 WDGLDCAE 1563 >gi|134244285 Notch homolog 3 [Homo sapiens] Length = 2321 Score = 135 bits (340), Expect = 2e-31 Identities = 140/497 (28%), Positives = 171/497 (34%), Gaps = 135/497 (27%) Query: 23 DPKGQHVCVASSPSAELQCCAGWR--QKDQECTIPICEGPDACQKDEVCVKPGL---CRC 77 +P +C + C GW + Q CE C+ C G+ C C Sbjct: 702 EPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACES-QPCRAGGTCSSDGMGFHCTC 760 Query: 78 KPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATG---ACQCQADRWGARCEF--- 131 PG G C P C + PC G+CE A G C C G RC+ Sbjct: 761 PPGVQGRQCELLSP-------CTPN-PCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVD 812 Query: 132 ----PCACGPHGRCDPATG--VCHCEPGWWSSTCRR---PCQCNTA--AARCEQATG--A 178 P CGPHG C G C C G+ +C + C N C+ G + Sbjct: 813 ECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFS 872 Query: 179 CVCKPGWWGRRC----------------------SFRCNC----HGSPCEQD-------- 204 C C PG+ G RC SF C C G CEQD Sbjct: 873 CSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSS 932 Query: 205 ------------SGRCACRPGWWGPECQQQCE------CVRGR-CSAA--SGECTCPPGF 243 S C CRPG+ G CQ + + C+ G CSAA CTC F Sbjct: 933 CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESF 992 Query: 244 RGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLP---- 299 G +C+ S Q + GRC TG+ C PGW+G C LP Sbjct: 993 TGPQCQTLVDWCSR--QPCQNGGRC-------VQTGAYCLCPPGWSGRLCDIRSLPCREA 1043 Query: 300 -GTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCE---DPCPTGTFGEDC--GS 353 G EQ C G+ + D+ H C G G CE DPC + C G Sbjct: 1044 AAQIGVRLEQLCQ--AGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPC----LAQPCQHGG 1097 Query: 354 TCPTCVQGSCDTVTGDCVCSAGYWGPSCN------ASCPAGFHGNNC-----SVPCECPE 402 TC + G C C GY G +C AS P HG +C C CP Sbjct: 1098 TCRGYMGGYM------CECLPGYNGDNCEDDVDECASQPCQ-HGGSCIDLVARYLCSCPP 1150 Query: 403 G----LCHPVSGSCQPG 415 G LC C PG Sbjct: 1151 GTLGVLCEINEDDCGPG 1167 Score = 129 bits (325), Expect = 9e-30 Identities = 150/548 (27%), Positives = 180/548 (32%), Gaps = 151/548 (27%) Query: 19 GSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCK 78 GS D G C A +C R D EC C GP C V C C Sbjct: 862 GSCQDGVGSFSCSCLPGFAGPRCA---RDVD-ECLSNPC-GPGTCTDH---VASFTCTCP 913 Query: 79 PGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCEF---PC 133 PG+ G HC P DC S C G C + C C+ GA C+ PC Sbjct: 914 PGYGGFHCEQDLP------DCSPSS-CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPC 966 Query: 134 ACGP--HGRCDPATGVCHCEPGWWSSTC-----------------RRPCQCNTAAARCEQ 174 P HG GVC + TC R+PCQ RC Q Sbjct: 967 LSRPCLHG------GVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQ---NGGRCVQ 1017 Query: 175 ATGACVCKPGWWGRRCSFR------------------CNCHGSPCEQDSGR-CACRPGWW 215 C+C PGW GR C R C G ++DS C C G Sbjct: 1018 TGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRT 1077 Query: 216 GPECQQQCE-CVR------GRCSAASG--ECTCPPGFRGARCE----------------- 249 G C+Q+ + C+ G C G C C PG+ G CE Sbjct: 1078 GSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSC 1137 Query: 250 --------LPCPAGSHGVQC---AHSCG---------RCKHNEPCSPDTGSCE-SCEPGW 288 CP G+ GV C CG RC HN C G +C PG+ Sbjct: 1138 IDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY 1197 Query: 289 NGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQR--CDPGWLGPRCE---DPCP 343 G +C+ C H H C D G R C G+ GPRC+ PC Sbjct: 1198 TGLRCEADI------NECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCE 1251 Query: 344 TGTFGEDC--GSTCPTCVQGSCDTVTGDCVCSAGYWGPSC--------NASCPAGFHGNN 393 + + C G C G +T C C+ +WGP C CP G Sbjct: 1252 S----QPCQHGGQCRPS-PGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQ 1306 Query: 394 C--SVPCECPEGL----CHPVSGSCQPGSGSRDTA----LIAGSLVPLLLLFLGLACCAC 443 C CP GL C GS PG+ + A L GS P L CA Sbjct: 1307 TPRGPRCACPPGLSGPSCRSFPGS-PPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQ 1365 Query: 444 CCWAPRSD 451 PR + Sbjct: 1366 GWTGPRCE 1373 Score = 128 bits (321), Expect = 2e-29 Identities = 134/535 (25%), Positives = 178/535 (33%), Gaps = 144/535 (26%) Query: 13 WTRGTQGSELDPKGQHVCVASSPS----AELQCCAGWRQKDQECTIPICEGPDACQKDEV 68 WT + +D VC + A C + C + + C +D + Sbjct: 306 WTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAI 365 Query: 69 C-VKP----GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQ 121 C P +C C PGF G C G + PC G+C G+ CQC Sbjct: 366 CDTNPVNGRAICTCPPGFTGGACDQDVDECSIGAN-----PCEHLGRCVNTQGSFLCQCG 420 Query: 122 ADRWGARCEFP---CACGP---HGRCDPATG--VCHCEPGWWSSTCR---RPCQ---CNT 167 G RCE C GP C G C C G+ + C CQ C Sbjct: 421 RGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVN 480 Query: 168 AAARCEQATG-ACVCKPGWWGRRCSFRCN-CHGSPC--------EQDSGRCACRPGWWGP 217 ++ G +C C G+ G C + C +PC + D C C G+ G Sbjct: 481 GGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGT 540 Query: 218 ECQQQCE------CVRGRC--SAASGECTCPPGFRGARCELP------------------ 251 C + + C GRC AS C C PG+ G RCE Sbjct: 541 LCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL 600 Query: 252 -------CPAGSHGVQCAHSCGRCKHNEPCSPDTGSCES--------CEPGWNGTQCQQP 296 CP+G+ GV C + C N PC+ G C C+PG+ G C Sbjct: 601 VDKYLCRCPSGTTGVNCEVNIDDCASN-PCT--FGVCRDGINRYDCVCQPGFTGPLCNVE 657 Query: 297 -------------------------CLPGTFGESC---EQQCPH--CRHGEACEPDTGHC 326 C PG+ C C H C HG + G Sbjct: 658 INECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFR 717 Query: 327 QRCDPGWLGPRC----------EDPCPTG----TFGEDCGSTCPTCVQGSCDTVTGDCVC 372 C+PGW GPRC PC G + G TCP VQG + C Sbjct: 718 CVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTP 777 Query: 373 SAGYWGPSCNA--------SCPAGFHG-------NNCSVPCEC-PEGLCHPVSGS 411 + G C + SCP G+ G + C+ P C P G+C ++GS Sbjct: 778 NPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGS 832 Score = 127 bits (318), Expect = 6e-29 Identities = 135/503 (26%), Positives = 164/503 (32%), Gaps = 143/503 (28%) Query: 29 VCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGL-CRCKPGFFGAHCS 87 VC A+ P C + + + C CQ CV+ G C C PG+ G C Sbjct: 976 VCSAAHPGFRCTCLESFTGPQCQTLVDWCSR-QPCQNGGRCVQTGAYCLCPPGWSGRLCD 1034 Query: 88 SRCPGQYWGPDCRESCP---------CHPHGQC--EPATGACQCQADRWGARCEF---PC 133 R CRE+ C GQC E ++ C C R G+ CE PC Sbjct: 1035 IR------SLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPC 1088 Query: 134 ACGP---HGRCDPATG--VCHCEPGWWSSTCR--------RPCQ----CNTAAARCEQAT 176 P G C G +C C PG+ C +PCQ C AR Sbjct: 1089 LAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARY---- 1144 Query: 177 GACVCKPGWWGRRCSFRCNCHGSPCEQDSG----------------RCACRPGWWGPECQ 220 C C PG G C + G DSG RC C PG+ G C+ Sbjct: 1145 -LCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203 Query: 221 QQC-ECVRGRCSAASGE-----------CTCPPGFRGARCEL---PCPAG--SHGVQCAH 263 EC G C AA C C GF G RC+ PC + HG QC Sbjct: 1204 ADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRP 1263 Query: 264 SCGRCKHNEPCSPDTGSCESCEPGWN-----------------GTQCQQP-------CLP 299 S G P T +C +P W G CQQ C P Sbjct: 1264 SPG------PGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPP 1317 Query: 300 GTFGESCEQ-------------QCPHCRHGEACEPDT----GHCQRCDPGWLGPRCEDPC 342 G G SC C HG +C P C C GW GPRCE P Sbjct: 1318 GLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCA-CAQGWTGPRCEAPA 1376 Query: 343 PTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE 402 E+ P C + +C GD C P C G+ G +CS+ P Sbjct: 1377 AAPEVSEE-----PRCPRAACQAKRGDQRCDRECNSPGC------GWDGGDCSLSVGDPW 1425 Query: 403 GLCHPV-------SGSCQPGSGS 418 C + + C P S Sbjct: 1426 RQCEALQCWRLFNNSRCDPACSS 1448 Score = 126 bits (317), Expect = 7e-29 Identities = 146/579 (25%), Positives = 186/579 (32%), Gaps = 201/579 (34%) Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCR----------CKP 79 C+ + S QC AG+ T P+CE P C G CR C P Sbjct: 174 CLNTPGSFRCQCPAGY-------TGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLP 226 Query: 80 GFFGAHC-------------------------SSRCPGQYWGPDCRESCP--------CH 106 GF G +C + +CP ++ G C E CH Sbjct: 227 GFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACH 286 Query: 107 PHGQCEPATGACQCQA-DRW-------------------GARCE-----FPCACGPHGRC 141 G C G C + W GA C F CAC P G+ Sbjct: 287 NGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCAC-PMGK- 344 Query: 142 DPATGV-CHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF---RCNCH 197 TG+ CH + S+ C C+T C C PG+ G C C+ Sbjct: 345 ---TGLLCHLDDACVSNPCHEDAICDTNPVN---GRAICTCPPGFTGGACDQDVDECSIG 398 Query: 198 GSPCE--------QDSGRCACRPGWWGPECQQQC-ECVRGRCSAASG--------ECTCP 240 +PCE Q S C C G+ GP C+ EC+ G C + C C Sbjct: 399 ANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICM 458 Query: 241 PGFRGARCEL--------PCPAGS------HGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286 GF G CE+ PC G +G C +C C D C S P Sbjct: 459 AGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSC--TCPSGFSGSTCQLDVDECAST-P 515 Query: 287 GWNGTQC-QQP------CLPGTFGESCEQQCPHC-----RHGEACEPDTGHCQRCDPGWL 334 NG +C QP C G G C++ C HG + C PG+ Sbjct: 516 CRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYT 575 Query: 335 GPRCEDP-------------------------CPTGTFGEDCGSTCPTCVQGSC------ 363 G RCE CP+GT G +C C C Sbjct: 576 GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR 635 Query: 364 DTVTG-DCVCSAGYWGPSCNA--------------SCPAGFHGNNC-------------- 394 D + DCVC G+ GP CN SC G +G C Sbjct: 636 DGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPP 695 Query: 395 SVPC---ECPEGLCHPVSGS----CQPG-SGSRDTALIA 425 S PC C G+C+ G C+PG SG R + +A Sbjct: 696 SHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLA 734 Score = 117 bits (292), Expect = 6e-26 Identities = 139/545 (25%), Positives = 163/545 (29%), Gaps = 198/545 (36%) Query: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESC------PCHPHGQCEPA 114 D C+ E C G C PG F +CP Y GP C PC G C + Sbjct: 160 DECRVGEPCRHGGTCLNTPGSFRC----QCPAGYTGPLCENPAVPCAPSPCRNGGTCRQS 215 Query: 115 ---TGACQCQADRWGARCEFPCACGPHGRC--------DPATGVCHCEPGWWSSTCRRP- 162 T C C G CE P RC T C C P W C Sbjct: 216 GDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDV 275 Query: 163 --CQCNTAAAR----CEQATG--ACVCKPGWWGRRCSFRCN-------CHGSPCEQD--S 205 CQ A C G +CVC GW G CS + HG+ C S Sbjct: 276 DECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVAS 335 Query: 206 GRCACRPGWWGPECQQQCECVRGRC--------SAASGE--CTCPPGFRGARCELPCPAG 255 CAC G G C CV C + +G CTCPPGF G C+ Sbjct: 336 FYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDEC 395 Query: 256 SHGVQ-CAH-------------SCGRCKHNEPCSPDTGSCES------------------ 283 S G C H CGR C D C S Sbjct: 396 SIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 455 Query: 284 -CEPGWNGTQCQ--------QPCL-----------------PGTFGESCE---QQCPH-- 312 C G+ GT C+ PC+ G G +C+ +C Sbjct: 456 ICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTP 515 Query: 313 CRHGEAC--EPDTGHCQ------------------------------------RCDPGWL 334 CR+G C +PD C+ C PG+ Sbjct: 516 CRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYT 575 Query: 335 GPRCEDP-------------------------CPTGTFGEDCGSTCPTCVQGSC------ 363 G RCE CP+GT G +C C C Sbjct: 576 GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR 635 Query: 364 DTVTG-DCVCSAGYWGPSCN------ASCPAGFHGNNC-----SVPCECPEG----LCHP 407 D + DCVC G+ GP CN AS P G G +C C CP G LC P Sbjct: 636 DGINRYDCVCQPGFTGPLCNVEINECASSPCG-EGGSCVDGENGFRCLCPPGSLPPLCLP 694 Query: 408 VSGSC 412 S C Sbjct: 695 PSHPC 699 Score = 116 bits (291), Expect = 7e-26 Identities = 136/515 (26%), Positives = 172/515 (33%), Gaps = 141/515 (27%) Query: 7 LPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPI------CEGP 60 LPLLLL G+ P C+ SP A C ++ C P C+ Sbjct: 27 LPLLLLLAG--PGAAAPP-----CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE 79 Query: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPC-------------HP 107 D C C G+C+ A S RCP + GPDC PC P Sbjct: 80 DPCHSGP-CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGP 138 Query: 108 HGQ----CEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPC 163 G+ C P C++D R PC G P + C C G+ C P Sbjct: 139 DGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPA 198 Query: 164 -QCNTAAAR----CEQA---TGACVCKPGWWGRRCSFRC-NCHGSPCEQ--------DSG 206 C + R C Q+ T C C PG+ G+ C +C G C ++ Sbjct: 199 VPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTY 258 Query: 207 RCACRPGWWG-------PECQQQ------------------CECVRG----RCSAASGEC 237 C C P W G ECQ Q C CV G CS +C Sbjct: 259 NCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDC 318 Query: 238 TCPPGFRGARCE-------LPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCE-------- 282 F GA C CP G G+ C H C N PC D C+ Sbjct: 319 ATAVCFHGATCHDRVASFYCACPMGKTGLLC-HLDDACVSN-PCHED-AICDTNPVNGRA 375 Query: 283 --SCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGH--CQRCDPGWLGPRC 338 +C PG+ G C Q + C C H C G CQ C G+ GPRC Sbjct: 376 ICTCPPGFTGGACDQDV------DECSIGANPCEHLGRCVNTQGSFLCQ-CGRGYTGPRC 428 Query: 339 EDPCPTGTFGEDCGSTCPTCVQGSCDTVTGD--CVCSAGYWGPSC--------------- 381 E T +C S P Q +C G C+C AG+ G C Sbjct: 429 E------TDVNECLSG-PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNG 481 Query: 382 ----------NASCPAGFHGNNCSVPC-ECPEGLC 405 + +CP+GF G+ C + EC C Sbjct: 482 GVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPC 516 Score = 113 bits (282), Expect = 8e-25 Identities = 92/315 (29%), Positives = 113/315 (35%), Gaps = 82/315 (26%) Query: 162 PCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQ 221 PC + AC+C PGW G RC CH PC +GR C+ + Sbjct: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPC---AGRGVCQSSVVAGTARF 104 Query: 222 QCECVRG----RCSAASGECTCPPGFRGARCEL--------PCPAGSHGVQCAHSCGRCK 269 C C RG CS C P GARC + CP G G C C+ Sbjct: 105 SCRCPRGFRGPDCSLPD-PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECR 163 Query: 270 HNEPC--------SPDTGSCESCEPGWNGTQCQQP------------------------- 296 EPC +P + C+ C G+ G C+ P Sbjct: 164 VGEPCRHGGTCLNTPGSFRCQ-CPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDC 222 Query: 297 -CLPGTFGESCE---QQCP--HCRHGEACEP--DTGHCQRCDPGWLGPRCE---DPCPTG 345 CLPG G++CE CP C +G C +T +CQ C P W G C D C Sbjct: 223 ACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQ-CPPEWTGQFCTEDVDECQLQ 281 Query: 346 TFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNAS---CPAG--FHGNNC-----S 395 G TC + G CVC G+ G SC+ + C FHG C S Sbjct: 282 PNACHNGGTCFNTLGGH------SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVAS 335 Query: 396 VPCECPEG----LCH 406 C CP G LCH Sbjct: 336 FYCACPMGKTGLLCH 350 >gi|143770880 laminin, beta 4 [Homo sapiens] Length = 1761 Score = 135 bits (340), Expect = 2e-31 Identities = 109/400 (27%), Positives = 145/400 (36%), Gaps = 88/400 (22%) Query: 73 GLCRCKPGFFGAHCSSRCPGQY-WGPDCRESCPCHPHGQ----CEPATGACQCQADRWGA 127 G C+CKP G C G Y G C CHP G C+ TG C C + G Sbjct: 786 GQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGR 845 Query: 128 RCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV------- 180 RC+ C G++ PC CN A C+ TG+C Sbjct: 846 RCD------------------RCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTT 887 Query: 181 ------CKPGWWGRRCSFR----CNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRC 230 C G++G S + C C P +C W + C C++G Sbjct: 888 GRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDV--ICNCLQGYT 945 Query: 231 SAASGECTC----PPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286 GEC+ P GA C+ PC A ++ + E CS TG C C Sbjct: 946 GTQCGECSTGFYGNPRISGAPCQ-PC-ACNNNIDVTDP-------ESCSRVTGECLRCLH 996 Query: 287 GWNGTQCQQPCLPGTFGESCEQQCPHCR-HGEA--------------CEPDTGHCQRCDP 331 G CQ C PG +G + Q C C H C+P TG C C P Sbjct: 997 NTQGANCQL-CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP-CLP 1054 Query: 332 GWLGPRCEDPCPTGTFGEDCGSTCPTC-------VQGSCDTVTGDCVCSAGYWGPSCNAS 384 G C D C G + G C +C CD +TG C C GY G C + Sbjct: 1055 NVTGLAC-DRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRC-SE 1112 Query: 385 CPAGFHGN--NCSVPCEC-----PEGLCHPVSGSCQPGSG 417 C ++G+ +PC+C + +C P +G C+ G Sbjct: 1113 CQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREG 1152 Score = 82.4 bits (202), Expect = 2e-15 Identities = 70/229 (30%), Positives = 87/229 (37%), Gaps = 45/229 (19%) Query: 223 CEC-----VRGRCSAASGECTCPPGFRGARCELPCPAGS-----HGVQCAHSCGRCKHNE 272 C+C V CS G+C C P G C+ C GS HG H + + Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGCHPCHCHPQGSKDT 827 Query: 273 PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPG 332 C TG C C +G +C + CL G FG CP R E C+P+TG C C Sbjct: 828 VCDQVTGQCP-CHGEVSGRRCDR-CLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGF 885 Query: 333 WLGPRCEDPCPTGTFGE-DCGSTCPTCV-----------QGSC--DTVTGD--CVCSAGY 376 G CE C G +G G C C+ SC + + D C C GY Sbjct: 886 TTGRNCE-RCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGY 944 Query: 377 WGPSCNASCPAGFHGN------NCSVPCECPEGL-------CHPVSGSC 412 G C C GF+GN C PC C + C V+G C Sbjct: 945 TGTQC-GECSTGFYGNPRISGAPCQ-PCACNNNIDVTDPESCSRVTGEC 991 Score = 81.3 bits (199), Expect = 3e-15 Identities = 64/233 (27%), Positives = 81/233 (34%), Gaps = 83/233 (35%) Query: 74 LCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG-----------QCEPATGAC-QCQ 121 +C C G+ G C G Y P PC P C TG C +C Sbjct: 937 ICNCLQGYTGTQCGECSTGFYGNPRI-SGAPCQPCACNNNIDVTDPESCSRVTGECLRCL 995 Query: 122 ADRWGARCEF-------------------------PCACGPHGR---CDPATGVCHCEP- 152 + GA C+ P C P G CDP TG C C P Sbjct: 996 HNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPN 1055 Query: 153 -----------GWWSSTCRRPCQC------NTAAARCEQATGACVCKPGWWGRRCSFRC- 194 G+W+ R CQ + ++ C+Q TG C CK G+ G+RCS C Sbjct: 1056 VTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS-ECQ 1114 Query: 195 -NCHGSP------------------CEQDSGRCACRPGWWGPECQQQCECVRG 228 N +G P C+ D+G C CR G G C + C RG Sbjct: 1115 ENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDR---CARG 1164 Score = 64.3 bits (155), Expect = 4e-10 Identities = 73/285 (25%), Positives = 98/285 (34%), Gaps = 88/285 (30%) Query: 73 GLCRCKPGFFGAHCSSRCPGQY----WGPD-------CRESCPCHPHG-QCE-------- 112 G C C+ G +C RC + W P CR SC C+ H +C Sbjct: 293 GQCVCQHNTDGPNCE-RCKDFFQDAPWRPAADLQDNACR-SCSCNSHSSRCHFDMTTYLA 350 Query: 113 ---PATGACQ-CQADRWGARCE--------------------FPCACGPHGRCDPATGVC 148 + G C+ CQ + G C+ PC C P G V Sbjct: 351 SGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVS 410 Query: 149 HCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS-------FRCNCHGS-- 199 H +P S + C+ N A+C+Q CKP +G + CN GS Sbjct: 411 HSDPALGSVAGQCLCKENVEGAKCDQ------CKPNHYGLSATDPLGCQPCDCNPLGSLP 464 Query: 200 --PCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSH 257 C+ D+G+C C G C+ EC G + C P C+ C G Sbjct: 465 FLTCDVDTGQCLCLSYVTGAHCE---ECTVGYWGLGNHLHGCSP------CD--CDIGG- 512 Query: 258 GVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302 ++ CSP G CE C P G C +P PG F Sbjct: 513 -----------AYSNVCSPKNGQCE-CRPHVTGRSCSEPA-PGYF 544 Score = 60.5 bits (145), Expect = 6e-09 Identities = 73/281 (25%), Positives = 101/281 (35%), Gaps = 43/281 (15%) Query: 160 RRPCQCNTAAARC---EQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG 216 R C CN A+ C ++ G PG +C + N G CE+ P W Sbjct: 262 RGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAP--WR 319 Query: 217 PECQQQCECVRG-RCSAASGEC-------TCPPGFRGARCELPCPAGSHGVQCAHSCGRC 268 P Q R C++ S C G G CE C + G C C Sbjct: 320 PAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCE-DCQHNTEGQHCDR-CRPL 377 Query: 269 KHNEPCSP--DTGSCESCEPGWNGTQCQQPCLPGTFGE--SCEQQCPHCRHGEACEPDTG 324 + +P D +C CE +GT C+ + S QC + E + Sbjct: 378 FYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAK---- 433 Query: 325 HCQRCDPGWLGPRCEDPCPTGTFGEDCG--STCPTCVQGSCDTVTGDCVCSAGYWGPSCN 382 C +C P G DP G DC + P +CD TG C+C + G C Sbjct: 434 -CDQCKPNHYGLSATDPL--GCQPCDCNPLGSLPFL---TCDVDTGQCLCLSYVTGAHCE 487 Query: 383 ASCPAGF-----HGNNCSVPCECPEG-----LCHPVSGSCQ 413 C G+ H + CS PC+C G +C P +G C+ Sbjct: 488 -ECTVGYWGLGNHLHGCS-PCDCDIGGAYSNVCSPKNGQCE 526 Score = 53.9 bits (128), Expect = 6e-07 Identities = 77/326 (23%), Positives = 102/326 (31%), Gaps = 79/326 (24%) Query: 100 RESCPCHPHG-QCEPAT--------------GACQCQADRWGARCEFPCACGPHGRCDPA 144 R SC C+ H +C P G C CQ + G CE RC Sbjct: 262 RGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCE---------RCKDF 312 Query: 145 TGVCHCEPG--WWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS-FRCNCHGSPC 201 P + CR C CN+ ++RC + G G C + N G C Sbjct: 313 FQDAPWRPAADLQDNACRS-CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHC 371 Query: 202 EQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQC 261 ++ CRP ++ R S C +PC G Sbjct: 372 DR------CRPLFY-----------RDPLKTISDPYAC----------IPCECDPDGTIS 404 Query: 262 AHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQ--CPHCRHGE-- 317 C H++P C+ G +C Q C P +G S C C Sbjct: 405 GGIC--VSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGCQPCDCNPLG 461 Query: 318 -----ACEPDTGHCQRCDPGWLGPRCEDPCPTGTFG-----EDCGSTCPTCVQGS----C 363 C+ DTG C C G CE+ C G +G C S C + G+ C Sbjct: 462 SLPFLTCDVDTGQCL-CLSYVTGAHCEE-CTVGYWGLGNHLHGC-SPCDCDIGGAYSNVC 518 Query: 364 DTVTGDCVCSAGYWGPSCNASCPAGF 389 G C C G SC+ P F Sbjct: 519 SPKNGQCECRPHVTGRSCSEPAPGYF 544 Score = 50.8 bits (120), Expect = 5e-06 Identities = 53/210 (25%), Positives = 74/210 (35%), Gaps = 37/210 (17%) Query: 226 VRGRCSAASGECTCPPGFRGARCELPCPAGS-HG-VQCAHS-----CGRCK---HNEPCS 275 VRG C C P + R ++ P G HG C H+ C RCK + P Sbjct: 261 VRGSCFCNGHASECRP-MQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWR 319 Query: 276 P----DTGSCESCEPGWNGTQCQQPCLP-----GTFGESCEQQCPHCRHGEACEPDTGHC 326 P +C SC + ++C G G CE C H G+ HC Sbjct: 320 PAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCED-CQHNTEGQ-------HC 371 Query: 327 QRCDPGWL--------GPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWG 378 RC P + P PC G G C + + +V G C+C G Sbjct: 372 DRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEG 431 Query: 379 PSCNASCPAGFHGNNCSVPCECPEGLCHPV 408 C+ C +G + + P C C+P+ Sbjct: 432 AKCD-QCKPNHYGLSATDPLGCQPCDCNPL 460 Score = 48.1 bits (113), Expect = 3e-05 Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 9/92 (9%) Query: 73 GLCRCKPGFFGAHCSSRCPGQYWG--PDCRESCPCHPHGQ----CEPATGACQCQADRWG 126 G C CK G+ G C S C Y+G P C C+ G C+P TG C+C+ G Sbjct: 1097 GQCPCKLGYGGKRC-SECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSG 1155 Query: 127 ARCEFPCACGPHGRCDPATGVCHCEPGWWSST 158 RC+ CA G H + P CH W T Sbjct: 1156 QRCD-RCARG-HSQEFPTCLQCHLCFDQWDHT 1185 Score = 37.7 bits (86), Expect = 0.044 Identities = 29/93 (31%), Positives = 30/93 (32%), Gaps = 23/93 (24%) Query: 70 VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARC 129 V G C C GAHC C YWG H HG C P C D GA Sbjct: 470 VDTGQCLCLSYVTGAHC-EECTVGYWG------LGNHLHG-CSP------CDCDIGGAYS 515 Query: 130 EFPCACGPHGRCDPATGVCHCEPGWWSSTCRRP 162 C P G C C P +C P Sbjct: 516 NV---------CSPKNGQCECRPHVTGRSCSEP 539 Score = 30.4 bits (67), Expect = 7.0 Identities = 11/27 (40%), Positives = 14/27 (51%) Query: 71 KPGLCRCKPGFFGAHCSSRCPGQYWGP 97 K G C C+P G CS PG ++ P Sbjct: 521 KNGQCECRPHVTGRSCSEPAPGYFFAP 547 >gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo sapiens] Length = 3118 Score = 134 bits (338), Expect = 3e-31 Identities = 124/467 (26%), Positives = 163/467 (34%), Gaps = 132/467 (28%) Query: 74 LCRCKPGFFGAHCSS------RCPGQYWGPDCRESCPCHPHGQ-CEPATGAC-QCQADRW 125 +C+C PG+ G+ C S R G +G C E C C H + C+ TG C C+ Sbjct: 723 VCQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKDHTG 781 Query: 126 GARCE------------------FPCACGPHGRCDPATGVCH-----------CEPGWWS 156 G C+ PCAC + + + CH C G+ Sbjct: 782 GPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTG 841 Query: 157 STCRR-----------------PCQCN-----TAAARCEQATGAC-VCKPGWWGRRCSF- 192 C R PCQCN + C+ +G+C +CKPG GR C Sbjct: 842 PRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELC 901 Query: 193 -----------------RCNCHGS---PCEQDSGRCACRPGWWGPEC----------QQQ 222 RCN GS C +G+C CR G C Q Sbjct: 902 ADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSA 961 Query: 223 CECVRGRCSA---------ASGECTCPPGFRGARCELPCPAGSHGVQ----CAHSCGRCK 269 CV C++ SG+C C PG G +C+ C G Q A C Sbjct: 962 RGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCD-RCAHGYFNFQEGGCTACECSHLG 1020 Query: 270 HNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA------CEPDT 323 +N C P TG C C P G +C + C P T+G S C C C +T Sbjct: 1021 NN--CDPKTGRC-ICPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVGSLDFQCNVNT 1076 Query: 324 GHCQRCDPGWLGPRCEDPCPTGTFGE------DC---GSTCPTC----VQGSCDTVTGDC 370 G C C P + G +C + C G + DC G+ TC + SC TG C Sbjct: 1077 GQC-NCHPKFSGAKCTE-CSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQC 1134 Query: 371 VCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSG 417 C G C+ C G G + P C C + C G Sbjct: 1135 TCKVNVEGIHCD-RCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKG 1180 Score = 111 bits (278), Expect = 2e-24 Identities = 106/351 (30%), Positives = 132/351 (37%), Gaps = 65/351 (18%) Query: 101 ESCPCHP-HGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPAT---GVCHCEPGWWS 156 ES +P G A CQC G+ CE +C P R T G+C Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCE---SCWPRHRRVNGTIFGGIC-------- 754 Query: 157 STCRRPCQCNTAAARCEQATGACV-CKPGWWGRRCSFRC--NCHGSPCE---QDSGRCAC 210 PCQC A C+ TG C+ CK G C +C +G P + +D CAC Sbjct: 755 ----EPCQCFGHAESCDDVTGECLNCKDHTGGPYCD-KCLPGFYGEPTKGTSEDCQPCAC 809 Query: 211 RPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQC--AHSCGRC 268 C R G CP G+ G RCE C G G SC C Sbjct: 810 PLNIPSNNFSPTCHLDRSLGLICDG---CPVGYTGPRCE-RCAEGYFGQPSVPGGSCQPC 865 Query: 269 KHNE--------PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCE-QQCPHCR----- 314 + N+ C +GSC C+PG G C+ C G FG++ + + C CR Sbjct: 866 QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL-CADGYFGDAVDAKNCQPCRCNAGG 924 Query: 315 -HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS-------CDTV 366 E C TG C+ C G RC D C GTFG C C S C+ Sbjct: 925 SFSEVCHSQTGQCE-CRANVQGQRC-DKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEE- 981 Query: 367 TGDCVCSAGYWGPSCNASCPAG---FHGNNCSVPCECPE--GLCHPVSGSC 412 +G C C G G C+ C G F C+ CEC C P +G C Sbjct: 982 SGQCWCQPGVTGKKCD-RCAHGYFNFQEGGCTA-CECSHLGNNCDPKTGRC 1030 Score = 101 bits (252), Expect = 2e-21 Identities = 72/228 (31%), Positives = 95/228 (41%), Gaps = 46/228 (20%) Query: 228 GRCSAASGECTCPPGFRGARCELPCPAGS--HGVQCAHSCGRCK---HNEPCSPDTGSCE 282 G +AA C CPPG+ G+ CE P +G C C+ H E C TG C Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECL 774 Query: 283 SCEPGWNGTQCQQPCLPGTFGE------------SCEQQCPHCRHGEACEPDTG---HCQ 327 +C+ G C + CLPG +GE +C P C D C Sbjct: 775 NCKDHTGGPYCDK-CLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICD 833 Query: 328 RCDPGWLGPRCEDPCPTGTFGEDC--GSTCPTC---------VQGSCDTVTGDC-VCSAG 375 C G+ GPRCE C G FG+ G +C C + GSCD+++G C +C G Sbjct: 834 GCPVGYTGPRCE-RCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPG 892 Query: 376 YWGPSCNASCPAGFHGN-----NCSVPCECPEG-----LCHPVSGSCQ 413 G C C G+ G+ NC PC C G +CH +G C+ Sbjct: 893 TTGRYCEL-CADGYFGDAVDAKNCQ-PCRCNAGGSFSEVCHSQTGQCE 938 Score = 85.9 bits (211), Expect = 1e-16 Identities = 82/321 (25%), Positives = 110/321 (34%), Gaps = 90/321 (28%) Query: 67 EVC-VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG------QCEPATGACQ 119 EVC + G C C+ G C G + R PC+ + CE +G C Sbjct: 928 EVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW 986 Query: 120 CQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGAC 179 CQ G +C+ CA HG + G C C+C+ C+ TG C Sbjct: 987 CQPGVTGKKCD-RCA---HGYFNFQEGGC------------TACECSHLGNNCDPKTGRC 1030 Query: 180 VCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC--------VRGRCS 231 +C P G +CS C P WG C+ + +C+ Sbjct: 1031 ICPPNTIGEKCS-----------------KCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073 Query: 232 AASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGT 291 +G+C C P F GA+C C R N P C C+ Sbjct: 1074 VNTGQCNCHPKFSGAKCT--------------ECSRGHWNYP------RCNLCD------ 1107 Query: 292 QCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDC 351 C LPGT +C+ + C +C TG C C G C D C G FG D Sbjct: 1108 -C---FLPGTDATTCDSETKKC----SCSDQTGQC-TCKVNVEGIHC-DRCRPGKFGLDA 1157 Query: 352 GST--CPTCVQGSCDTVTGDC 370 + C +C C T C Sbjct: 1158 KNPLGCSSCY---CFGTTTQC 1175 Score = 75.9 bits (185), Expect = 1e-13 Identities = 64/238 (26%), Positives = 87/238 (36%), Gaps = 50/238 (21%) Query: 69 CVKPGLCRCKPGFFGAHCSSRCPGQYWG---PDCRESCPC-HPHGQCEPATGACQCQADR 124 C + G C C+PG G C RC Y+ C +C C H C+P TG C C + Sbjct: 979 CEESGQCWCQPGVTGKKC-DRCAHGYFNFQEGGC-TACECSHLGNNCDPKTGRCICPPNT 1036 Query: 125 WGARCEFPCACGPHGRCDPATGVCHCEPGWWS---STCRRPCQCNTAAA---RCEQATGA 178 G +C C P W +T + C C+T + +C TG Sbjct: 1037 IGEKCS------------------KCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ 1078 Query: 179 CVCKPGWWGRRCSFRCNCHGSPCEQDSGRCAC-RPGWWGPECQQQCECVRGRCSAASGEC 237 C C P + G +C+ C+ G C C PG C E + CS +G+C Sbjct: 1079 CNCHPKFSGAKCT-ECS-RGHWNYPRCNLCDCFLPGTDATTCDS--ETKKCSCSDQTGQC 1134 Query: 238 TCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ 295 TC G C+ C G G+ + G C SC TQC + Sbjct: 1135 TCKVNVEGIHCD-RCRPGKFGLDAKNPLG--------------CSSCYCFGTTTQCSE 1177 Score = 70.1 bits (170), Expect = 8e-12 Identities = 53/165 (32%), Positives = 67/165 (40%), Gaps = 35/165 (21%) Query: 284 CEPGWNGTQCQQPCLP------GT-FGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGP 336 C PG+ G+ C+ C P GT FG CE C H E+C+ TG C C GP Sbjct: 726 CPPGYTGSSCES-CWPRHRRVNGTIFGGICEP-CQCFGHAESCDDVTGECLNCKDHTGGP 783 Query: 337 RCEDPCPTGTFGEDCGSTCPTCVQGSC------DTVTGDCV-----------CSAGYWGP 379 C D C G +GE T C +C + + C C GY GP Sbjct: 784 YC-DKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGP 842 Query: 380 SCNASCPAGFHGN------NCSVPCECPEGLCHPVSGSCQPGSGS 418 C C G+ G +C PC+C + L + GSC SGS Sbjct: 843 RCER-CAEGYFGQPSVPGGSCQ-PCQCNDNLDFSIPGSCDSLSGS 885 Score = 64.3 bits (155), Expect = 4e-10 Identities = 55/181 (30%), Positives = 71/181 (39%), Gaps = 35/181 (19%) Query: 236 ECTCPPGFRGARCE--LPC-------PAGSHGVQCAHSCGRCK---HNEPCSPDTGSCES 283 +C CP G+ G CE LP P G +C C+ H+ C P+T C++ Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438 Query: 284 CEPGWNGTQCQQPCLPGTFG------ESCEQ-QCPHCRHGEACEP-------DTGHCQRC 329 C+ G C++ C G +G C+Q CP P D C C Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497 Query: 330 DPGWLGPRCEDPCP--TGTFGEDCGST--CPTCVQGS----CDTVTGDCVCSAGYWGPSC 381 G+ G CE P TG+ G GS C GS CD VTG C C G G C Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557 Query: 382 N 382 + Sbjct: 1558 D 1558 Score = 57.8 bits (138), Expect = 4e-08 Identities = 56/196 (28%), Positives = 75/196 (38%), Gaps = 38/196 (19%) Query: 75 CRCKPGFFGAHCSSRCPGQYW----------GPDCRESCPCHPHGQ---CEPATGACQ-C 120 C C G+ G C + PG Y GP PC +G C+P T CQ C Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439 Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180 Q G CE CA G +G C + C C ++ + +CV Sbjct: 1440 QHHTAGDFCE-RCALGYYGIVKGLPNDC------------QQCACPLISSS-NNFSPSCV 1485 Query: 181 CKPGWWGRRCSFRC--NCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRGRCSAA 233 + G RC+ C G CE+ + PG G CQ+ CEC + C Sbjct: 1486 AE-GLDDYRCT-ACPRGYEGQYCERCAPGYTGSPGNPGGSCQE-CECDPYGSLPVPCDPV 1542 Query: 234 SGECTCPPGFRGARCE 249 +G CTC PG G +C+ Sbjct: 1543 TGFCTCRPGATGRKCD 1558 Score = 57.4 bits (137), Expect = 5e-08 Identities = 54/171 (31%), Positives = 68/171 (39%), Gaps = 36/171 (21%) Query: 280 SCESCEPGWNGTQCQQPC-LPG-TFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPR 337 SCE+C PG+ + Q PG T G QC H C+P+T CQ C G Sbjct: 1390 SCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNG--HSSLCDPETSICQNCQHHTAGDF 1447 Query: 338 CEDPCPTGTFG------EDCGSTCPTCVQGSCDTVTGDCV-----------CSAGYWGPS 380 CE C G +G DC C + S + + CV C GY G Sbjct: 1448 CE-RCALGYYGIVKGLPNDC-QQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQY 1505 Query: 381 CNASCPA-----GFHGNNCSVPCEC-PEGL----CHPVSG--SCQPGSGSR 419 C P G G +C CEC P G C PV+G +C+PG+ R Sbjct: 1506 CERCAPGYTGSPGNPGGSCQ-ECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555 Score = 51.2 bits (121), Expect = 4e-06 Identities = 59/223 (26%), Positives = 79/223 (35%), Gaps = 41/223 (18%) Query: 40 QCCAGWRQKD---------QECTIPICEGP-DACQKDEVCVKPGLC-RCKPGFFGAHCSS 88 QCC G+ QK EC C G + C DE + L + + G Sbjct: 320 QCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCI 379 Query: 89 RCPGQYWGPDCRESCP---CHPHGQCEPATGACQ-CQADRWGARCEFPCACGPHGRCDPA 144 C G +C E+C P G CQ C D G+ E H R A Sbjct: 380 NCTQNTAGINC-ETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLA 438 Query: 145 TGVCHCEPGWWSSTCRR------------PCQCNTAAARCEQ-ATGACVCKPGWWGRRCS 191 G CHC+ G+ +C R C C+ ++ E G C+CK G CS Sbjct: 439 PGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCS 498 Query: 192 FRCNCHGSPCEQDSGRCACRPGWWG-PECQQQCECVRGRCSAA 233 RC ++D+ W G EC C V RC ++ Sbjct: 499 -RCKSGFFNLQEDN--------WKGCDEC--FCSGVSNRCQSS 530 Score = 46.6 bits (109), Expect = 1e-04 Identities = 58/224 (25%), Positives = 74/224 (33%), Gaps = 70/224 (31%) Query: 56 ICEG-PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGP----------DCRESCP 104 IC G AC D K C C+ G C CPG + P +C E+C Sbjct: 288 ICYGHARACPLDPATNK-SRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC-EACN 345 Query: 105 CHPHGQCEP---------------------ATGAC-QCQADRWGARCEFPCACG---PHG 139 C HG+ E G C C + G CE C G P G Sbjct: 346 C--HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE-TCTDGFFRPKG 402 Query: 140 -------RCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS- 191 C P CHC+P + C + AR A G+C CK G+ G C Sbjct: 403 VSPNYPRPCQP----CHCDP---IGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDR 455 Query: 192 -----------FRCNCHGSPCEQDS---GRCACRPGWWGPECQQ 221 CNC G + + G C C+ G +C + Sbjct: 456 CARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSR 499 Score = 46.2 bits (108), Expect = 1e-04 Identities = 49/179 (27%), Positives = 65/179 (36%), Gaps = 38/179 (21%) Query: 19 GSELDPK-GQHVCVASSPSAELQCCAG--WRQKDQECTIPICEGPDACQKDEV------C 69 G+ DPK G+ +C ++ + CA W I G AC V C Sbjct: 1020 GNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS-------ITTGCKACNCSTVGSLDFQC 1072 Query: 70 -VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADR 124 V G C C P F GA C+ G + P C C C G C+ T C C +D+ Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRC-NLCDCFLPGTDATTCDSETKKCSC-SDQ 1130 Query: 125 WGARCEFPCACGPHG-RCDPATGVCHCEPGWWSSTCRRP-----CQCNTAAARCEQATG 177 G + C G CD C PG + + P C C +C +A G Sbjct: 1131 TG---QCTCKVNVEGIHCD------RCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKG 1180 Score = 42.4 bits (98), Expect = 0.002 Identities = 51/215 (23%), Positives = 72/215 (33%), Gaps = 76/215 (35%) Query: 230 CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWN 289 C + C P +RCE C+HN C SC+ C PG++ Sbjct: 289 CYGHARACPLDPATNKSRCE------------------CEHNT-CGD---SCDQCCPGFH 326 Query: 290 GTQCQQPCLPGTFGESCEQQCPHCRHGEA------------------------------C 319 Q+P GTF E + +C HG+A C Sbjct: 327 ----QKPWRAGTFLTKTECEACNC-HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINC 381 Query: 320 EPDTG--HCQRCDPGWLGPR---------CEDPC---PTGTFGEDCGSTCPTCVQGSCDT 365 +T +C+ C G+ P+ C+ PC P G+ E C +G Sbjct: 382 TQNTAGINCETCTDGFFRPKGVSPNYPRPCQ-PCHCDPIGSLNEVCVKDEKHARRG---L 437 Query: 366 VTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC 400 G C C G+ G SC+ C G+ G C C Sbjct: 438 APGSCHCKTGFGGVSCD-RCARGYTGYPDCKACNC 471 Score = 30.0 bits (66), Expect = 9.2 Identities = 18/58 (31%), Positives = 22/58 (37%), Gaps = 14/58 (24%) Query: 370 CVCSAGYWGPSCNASCPAGFHGNN------------CSVPCEC--PEGLCHPVSGSCQ 413 C C GY G SC A P + + VPC+C LC P + CQ Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ 1437 >gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sapiens] Length = 3122 Score = 134 bits (338), Expect = 3e-31 Identities = 124/467 (26%), Positives = 163/467 (34%), Gaps = 132/467 (28%) Query: 74 LCRCKPGFFGAHCSS------RCPGQYWGPDCRESCPCHPHGQ-CEPATGAC-QCQADRW 125 +C+C PG+ G+ C S R G +G C E C C H + C+ TG C C+ Sbjct: 723 VCQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKDHTG 781 Query: 126 GARCE------------------FPCACGPHGRCDPATGVCH-----------CEPGWWS 156 G C+ PCAC + + + CH C G+ Sbjct: 782 GPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTG 841 Query: 157 STCRR-----------------PCQCN-----TAAARCEQATGAC-VCKPGWWGRRCSF- 192 C R PCQCN + C+ +G+C +CKPG GR C Sbjct: 842 PRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELC 901 Query: 193 -----------------RCNCHGS---PCEQDSGRCACRPGWWGPEC----------QQQ 222 RCN GS C +G+C CR G C Q Sbjct: 902 ADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSA 961 Query: 223 CECVRGRCSA---------ASGECTCPPGFRGARCELPCPAGSHGVQ----CAHSCGRCK 269 CV C++ SG+C C PG G +C+ C G Q A C Sbjct: 962 RGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCD-RCAHGYFNFQEGGCTACECSHLG 1020 Query: 270 HNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA------CEPDT 323 +N C P TG C C P G +C + C P T+G S C C C +T Sbjct: 1021 NN--CDPKTGRC-ICPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVGSLDFQCNVNT 1076 Query: 324 GHCQRCDPGWLGPRCEDPCPTGTFGE------DC---GSTCPTC----VQGSCDTVTGDC 370 G C C P + G +C + C G + DC G+ TC + SC TG C Sbjct: 1077 GQC-NCHPKFSGAKCTE-CSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQC 1134 Query: 371 VCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSG 417 C G C+ C G G + P C C + C G Sbjct: 1135 TCKVNVEGIHCD-RCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKG 1180 Score = 111 bits (278), Expect = 2e-24 Identities = 106/351 (30%), Positives = 132/351 (37%), Gaps = 65/351 (18%) Query: 101 ESCPCHP-HGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPAT---GVCHCEPGWWS 156 ES +P G A CQC G+ CE +C P R T G+C Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCE---SCWPRHRRVNGTIFGGIC-------- 754 Query: 157 STCRRPCQCNTAAARCEQATGACV-CKPGWWGRRCSFRC--NCHGSPCE---QDSGRCAC 210 PCQC A C+ TG C+ CK G C +C +G P + +D CAC Sbjct: 755 ----EPCQCFGHAESCDDVTGECLNCKDHTGGPYCD-KCLPGFYGEPTKGTSEDCQPCAC 809 Query: 211 RPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQC--AHSCGRC 268 C R G CP G+ G RCE C G G SC C Sbjct: 810 PLNIPSNNFSPTCHLDRSLGLICDG---CPVGYTGPRCE-RCAEGYFGQPSVPGGSCQPC 865 Query: 269 KHNE--------PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCE-QQCPHCR----- 314 + N+ C +GSC C+PG G C+ C G FG++ + + C CR Sbjct: 866 QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL-CADGYFGDAVDAKNCQPCRCNAGG 924 Query: 315 -HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS-------CDTV 366 E C TG C+ C G RC D C GTFG C C S C+ Sbjct: 925 SFSEVCHSQTGQCE-CRANVQGQRC-DKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEE- 981 Query: 367 TGDCVCSAGYWGPSCNASCPAG---FHGNNCSVPCECPE--GLCHPVSGSC 412 +G C C G G C+ C G F C+ CEC C P +G C Sbjct: 982 SGQCWCQPGVTGKKCD-RCAHGYFNFQEGGCTA-CECSHLGNNCDPKTGRC 1030 Score = 101 bits (252), Expect = 2e-21 Identities = 72/228 (31%), Positives = 95/228 (41%), Gaps = 46/228 (20%) Query: 228 GRCSAASGECTCPPGFRGARCELPCPAGS--HGVQCAHSCGRCK---HNEPCSPDTGSCE 282 G +AA C CPPG+ G+ CE P +G C C+ H E C TG C Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECL 774 Query: 283 SCEPGWNGTQCQQPCLPGTFGE------------SCEQQCPHCRHGEACEPDTG---HCQ 327 +C+ G C + CLPG +GE +C P C D C Sbjct: 775 NCKDHTGGPYCDK-CLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICD 833 Query: 328 RCDPGWLGPRCEDPCPTGTFGEDC--GSTCPTC---------VQGSCDTVTGDC-VCSAG 375 C G+ GPRCE C G FG+ G +C C + GSCD+++G C +C G Sbjct: 834 GCPVGYTGPRCE-RCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPG 892 Query: 376 YWGPSCNASCPAGFHGN-----NCSVPCECPEG-----LCHPVSGSCQ 413 G C C G+ G+ NC PC C G +CH +G C+ Sbjct: 893 TTGRYCEL-CADGYFGDAVDAKNCQ-PCRCNAGGSFSEVCHSQTGQCE 938 Score = 85.9 bits (211), Expect = 1e-16 Identities = 82/321 (25%), Positives = 110/321 (34%), Gaps = 90/321 (28%) Query: 67 EVC-VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG------QCEPATGACQ 119 EVC + G C C+ G C G + R PC+ + CE +G C Sbjct: 928 EVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW 986 Query: 120 CQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGAC 179 CQ G +C+ CA HG + G C C+C+ C+ TG C Sbjct: 987 CQPGVTGKKCD-RCA---HGYFNFQEGGC------------TACECSHLGNNCDPKTGRC 1030 Query: 180 VCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC--------VRGRCS 231 +C P G +CS C P WG C+ + +C+ Sbjct: 1031 ICPPNTIGEKCS-----------------KCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073 Query: 232 AASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGT 291 +G+C C P F GA+C C R N P C C+ Sbjct: 1074 VNTGQCNCHPKFSGAKCT--------------ECSRGHWNYP------RCNLCD------ 1107 Query: 292 QCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDC 351 C LPGT +C+ + C +C TG C C G C D C G FG D Sbjct: 1108 -C---FLPGTDATTCDSETKKC----SCSDQTGQC-TCKVNVEGIHC-DRCRPGKFGLDA 1157 Query: 352 GST--CPTCVQGSCDTVTGDC 370 + C +C C T C Sbjct: 1158 KNPLGCSSCY---CFGTTTQC 1175 Score = 75.9 bits (185), Expect = 1e-13 Identities = 64/238 (26%), Positives = 87/238 (36%), Gaps = 50/238 (21%) Query: 69 CVKPGLCRCKPGFFGAHCSSRCPGQYWG---PDCRESCPC-HPHGQCEPATGACQCQADR 124 C + G C C+PG G C RC Y+ C +C C H C+P TG C C + Sbjct: 979 CEESGQCWCQPGVTGKKC-DRCAHGYFNFQEGGC-TACECSHLGNNCDPKTGRCICPPNT 1036 Query: 125 WGARCEFPCACGPHGRCDPATGVCHCEPGWWS---STCRRPCQCNTAAA---RCEQATGA 178 G +C C P W +T + C C+T + +C TG Sbjct: 1037 IGEKCS------------------KCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ 1078 Query: 179 CVCKPGWWGRRCSFRCNCHGSPCEQDSGRCAC-RPGWWGPECQQQCECVRGRCSAASGEC 237 C C P + G +C+ C+ G C C PG C E + CS +G+C Sbjct: 1079 CNCHPKFSGAKCT-ECS-RGHWNYPRCNLCDCFLPGTDATTCDS--ETKKCSCSDQTGQC 1134 Query: 238 TCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ 295 TC G C+ C G G+ + G C SC TQC + Sbjct: 1135 TCKVNVEGIHCD-RCRPGKFGLDAKNPLG--------------CSSCYCFGTTTQCSE 1177 Score = 70.1 bits (170), Expect = 8e-12 Identities = 53/165 (32%), Positives = 67/165 (40%), Gaps = 35/165 (21%) Query: 284 CEPGWNGTQCQQPCLP------GT-FGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGP 336 C PG+ G+ C+ C P GT FG CE C H E+C+ TG C C GP Sbjct: 726 CPPGYTGSSCES-CWPRHRRVNGTIFGGICEP-CQCFGHAESCDDVTGECLNCKDHTGGP 783 Query: 337 RCEDPCPTGTFGEDCGSTCPTCVQGSC------DTVTGDCV-----------CSAGYWGP 379 C D C G +GE T C +C + + C C GY GP Sbjct: 784 YC-DKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGP 842 Query: 380 SCNASCPAGFHGN------NCSVPCECPEGLCHPVSGSCQPGSGS 418 C C G+ G +C PC+C + L + GSC SGS Sbjct: 843 RCER-CAEGYFGQPSVPGGSCQ-PCQCNDNLDFSIPGSCDSLSGS 885 Score = 64.3 bits (155), Expect = 4e-10 Identities = 55/181 (30%), Positives = 71/181 (39%), Gaps = 35/181 (19%) Query: 236 ECTCPPGFRGARCE--LPC-------PAGSHGVQCAHSCGRCK---HNEPCSPDTGSCES 283 +C CP G+ G CE LP P G +C C+ H+ C P+T C++ Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438 Query: 284 CEPGWNGTQCQQPCLPGTFG------ESCEQ-QCPHCRHGEACEP-------DTGHCQRC 329 C+ G C++ C G +G C+Q CP P D C C Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497 Query: 330 DPGWLGPRCEDPCP--TGTFGEDCGST--CPTCVQGS----CDTVTGDCVCSAGYWGPSC 381 G+ G CE P TG+ G GS C GS CD VTG C C G G C Sbjct: 1498 PRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557 Query: 382 N 382 + Sbjct: 1558 D 1558 Score = 57.8 bits (138), Expect = 4e-08 Identities = 56/196 (28%), Positives = 75/196 (38%), Gaps = 38/196 (19%) Query: 75 CRCKPGFFGAHCSSRCPGQYW----------GPDCRESCPCHPHGQ---CEPATGACQ-C 120 C C G+ G C + PG Y GP PC +G C+P T CQ C Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439 Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180 Q G CE CA G +G C + C C ++ + +CV Sbjct: 1440 QHHTAGDFCE-RCALGYYGIVKGLPNDC------------QQCACPLISSS-NNFSPSCV 1485 Query: 181 CKPGWWGRRCSFRC--NCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRGRCSAA 233 + G RC+ C G CE+ + PG G CQ+ CEC + C Sbjct: 1486 AE-GLDDYRCT-ACPRGYEGQYCERCAPGYTGSPGNPGGSCQE-CECDPYGSLPVPCDPV 1542 Query: 234 SGECTCPPGFRGARCE 249 +G CTC PG G +C+ Sbjct: 1543 TGFCTCRPGATGRKCD 1558 Score = 57.4 bits (137), Expect = 5e-08 Identities = 54/171 (31%), Positives = 68/171 (39%), Gaps = 36/171 (21%) Query: 280 SCESCEPGWNGTQCQQPC-LPG-TFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPR 337 SCE+C PG+ + Q PG T G QC H C+P+T CQ C G Sbjct: 1390 SCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNG--HSSLCDPETSICQNCQHHTAGDF 1447 Query: 338 CEDPCPTGTFG------EDCGSTCPTCVQGSCDTVTGDCV-----------CSAGYWGPS 380 CE C G +G DC C + S + + CV C GY G Sbjct: 1448 CE-RCALGYYGIVKGLPNDC-QQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQY 1505 Query: 381 CNASCPA-----GFHGNNCSVPCEC-PEGL----CHPVSG--SCQPGSGSR 419 C P G G +C CEC P G C PV+G +C+PG+ R Sbjct: 1506 CERCAPGYTGSPGNPGGSCQ-ECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555 Score = 51.2 bits (121), Expect = 4e-06 Identities = 59/223 (26%), Positives = 79/223 (35%), Gaps = 41/223 (18%) Query: 40 QCCAGWRQKD---------QECTIPICEGP-DACQKDEVCVKPGLC-RCKPGFFGAHCSS 88 QCC G+ QK EC C G + C DE + L + + G Sbjct: 320 QCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCI 379 Query: 89 RCPGQYWGPDCRESCP---CHPHGQCEPATGACQ-CQADRWGARCEFPCACGPHGRCDPA 144 C G +C E+C P G CQ C D G+ E H R A Sbjct: 380 NCTQNTAGINC-ETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLA 438 Query: 145 TGVCHCEPGWWSSTCRR------------PCQCNTAAARCEQ-ATGACVCKPGWWGRRCS 191 G CHC+ G+ +C R C C+ ++ E G C+CK G CS Sbjct: 439 PGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCS 498 Query: 192 FRCNCHGSPCEQDSGRCACRPGWWG-PECQQQCECVRGRCSAA 233 RC ++D+ W G EC C V RC ++ Sbjct: 499 -RCKSGFFNLQEDN--------WKGCDEC--FCSGVSNRCQSS 530 Score = 46.6 bits (109), Expect = 1e-04 Identities = 58/224 (25%), Positives = 74/224 (33%), Gaps = 70/224 (31%) Query: 56 ICEG-PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGP----------DCRESCP 104 IC G AC D K C C+ G C CPG + P +C E+C Sbjct: 288 ICYGHARACPLDPATNK-SRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC-EACN 345 Query: 105 CHPHGQCEP---------------------ATGAC-QCQADRWGARCEFPCACG---PHG 139 C HG+ E G C C + G CE C G P G Sbjct: 346 C--HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE-TCTDGFFRPKG 402 Query: 140 -------RCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS- 191 C P CHC+P + C + AR A G+C CK G+ G C Sbjct: 403 VSPNYPRPCQP----CHCDP---IGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDR 455 Query: 192 -----------FRCNCHGSPCEQDS---GRCACRPGWWGPECQQ 221 CNC G + + G C C+ G +C + Sbjct: 456 CARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSR 499 Score = 46.2 bits (108), Expect = 1e-04 Identities = 49/179 (27%), Positives = 65/179 (36%), Gaps = 38/179 (21%) Query: 19 GSELDPK-GQHVCVASSPSAELQCCAG--WRQKDQECTIPICEGPDACQKDEV------C 69 G+ DPK G+ +C ++ + CA W I G AC V C Sbjct: 1020 GNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS-------ITTGCKACNCSTVGSLDFQC 1072 Query: 70 -VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADR 124 V G C C P F GA C+ G + P C C C G C+ T C C +D+ Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRC-NLCDCFLPGTDATTCDSETKKCSC-SDQ 1130 Query: 125 WGARCEFPCACGPHG-RCDPATGVCHCEPGWWSSTCRRP-----CQCNTAAARCEQATG 177 G + C G CD C PG + + P C C +C +A G Sbjct: 1131 TG---QCTCKVNVEGIHCD------RCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKG 1180 Score = 42.4 bits (98), Expect = 0.002 Identities = 51/215 (23%), Positives = 72/215 (33%), Gaps = 76/215 (35%) Query: 230 CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWN 289 C + C P +RCE C+HN C SC+ C PG++ Sbjct: 289 CYGHARACPLDPATNKSRCE------------------CEHNT-CGD---SCDQCCPGFH 326 Query: 290 GTQCQQPCLPGTFGESCEQQCPHCRHGEA------------------------------C 319 Q+P GTF E + +C HG+A C Sbjct: 327 ----QKPWRAGTFLTKTECEACNC-HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINC 381 Query: 320 EPDTG--HCQRCDPGWLGPR---------CEDPC---PTGTFGEDCGSTCPTCVQGSCDT 365 +T +C+ C G+ P+ C+ PC P G+ E C +G Sbjct: 382 TQNTAGINCETCTDGFFRPKGVSPNYPRPCQ-PCHCDPIGSLNEVCVKDEKHARRG---L 437 Query: 366 VTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC 400 G C C G+ G SC+ C G+ G C C Sbjct: 438 APGSCHCKTGFGGVSCD-RCARGYTGYPDCKACNC 471 Score = 30.0 bits (66), Expect = 9.2 Identities = 18/58 (31%), Positives = 22/58 (37%), Gaps = 14/58 (24%) Query: 370 CVCSAGYWGPSCNASCPAGFHGNN------------CSVPCEC--PEGLCHPVSGSCQ 413 C C GY G SC A P + + VPC+C LC P + CQ Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ 1437 >gi|24041035 notch 2 preproprotein [Homo sapiens] Length = 2471 Score = 133 bits (334), Expect = 8e-31 Identities = 131/465 (28%), Positives = 173/465 (37%), Gaps = 109/465 (23%) Query: 29 VCVASSPSAELQCCAGWRQKDQECTIPICE---GPDACQKDEVCVKPGL---CRCKPGFF 82 VCV + +C W Q CT + E P+ACQ C C C G+ Sbjct: 274 VCVDGVNTYNCRCPPQWT--GQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS 331 Query: 83 GAHCSSRCPGQYWGPDCRESCPCHPHGQC--EPATGACQCQADRWGARCEF-------PC 133 G CS DC + C P C A+ +C C + G C PC Sbjct: 332 GDDCSENID------DCAFAS-CTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPC 384 Query: 134 ACGPHGRCDPATG--VCHCEPGWWSSTCRRPC-QCNTA-------AARCEQATGA--CVC 181 G +P G +C C G+ + C +C A A +C GA C C Sbjct: 385 HKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC 444 Query: 182 KPGWWGRRCSFRCN-CHGSPCEQDSG--------RCACRPGWWGPECQ---QQCE---CV 226 G+ G RC N CH PC+ D+ C C PG+ G C+ +C+ CV Sbjct: 445 LKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCV 504 Query: 227 R-GRC--SAASGECTCPPGFRGARCEL--------PCPAGS------HGVQCAHSCG--- 266 G+C +C CPPGF G C++ PC G+ +G +C + G Sbjct: 505 NNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTG 564 Query: 267 -RCKHN-EPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHC------RHGEA 318 C+ N + C PD C+ G + C C PG G C Q C G Sbjct: 565 VLCEENIDNCDPDPCHHGQCQDGIDSYTCI--CNPGYMGAICSDQIDECYSSPCLNDGRC 622 Query: 319 CEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSC-DTVTG-DCVCSAGY 376 + G+ C PG G CE +DC S C+ G C D + CVCS G+ Sbjct: 623 IDLVNGYQCNCQPGTSGVNCEINF------DDCASN--PCIHGICMDGINRYSCVCSPGF 674 Query: 377 WGPSCN--------------ASCPAGFHGNNCSVPCECPEGLCHP 407 G CN A+C G +G C CPEG HP Sbjct: 675 TGQRCNIDIDECASNPCRKGATCINGVNGFRCI----CPEGPHHP 715 Score = 123 bits (308), Expect = 8e-28 Identities = 133/503 (26%), Positives = 175/503 (34%), Gaps = 146/503 (29%) Query: 41 CCAGWRQKDQECTIPICEG-PDACQKDEVCVKPG---LCRCKPGFFGAHCSSRCPGQYWG 96 C GW+ Q CTI I E C +C +C C PGF G C Sbjct: 861 CAPGWQ--GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDI------ 912 Query: 97 PDCRESCPCHPHGQCEPA--TGACQCQADRWGARCEF--------PCACGPHGRCDPATG 146 DC + PC G C T +C C G +C+ PC G G C Sbjct: 913 DDCLAN-PCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNG--GTCSDYVN 969 Query: 147 --VCHCEPGWWSSTCRRPC-QCNTAA----ARCEQATG--ACVCKPGWWGRRCSFRCN-C 196 C C+ G+ C +C ++ C +C+C G+ G C N C Sbjct: 970 SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINEC 1029 Query: 197 HGSPCEQD--------SGRCACRPGWWGPECQQQCE-CVRGRC--------SAASGECTC 239 PC + + RC+C G+ G CQ C R C A +C C Sbjct: 1030 SSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLC 1089 Query: 240 PPGFRGARCELP-----------------------------------CPAGSHGVQCAH- 263 P G+ GA C++P CP G G C Sbjct: 1090 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQ 1149 Query: 264 ----SCGRCKHNEPCSPDTGS--CESCEPGWNGTQCQ--------QPCL----------- 298 + C+H CS G CE C PG+ G C+ QPC Sbjct: 1150 LDECASNPCQHGATCSDFIGGYRCE-CVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNH 1208 Query: 299 ------PGTFGESCEQQC------PHCRHGEAC-EPDTGHCQRCDPGWLGPRCEDPCPTG 345 PGT G CE+ PHC +G C + G+ RC PG+ G RCE G Sbjct: 1209 FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE-----G 1263 Query: 346 TFGEDCGSTCPTCVQGSCDTVTGD--CVCSAGYWGPSCNA---SCP--AGFHGNNCSVPC 398 E + C + C +T D CVC + + G C CP +G C+V Sbjct: 1264 DINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVAS 1323 Query: 399 ECPEG-LCHPVSGSCQPG-SGSR 419 P+G +C C PG SG+R Sbjct: 1324 NMPDGFICR-----CPPGFSGAR 1341 Score = 118 bits (295), Expect = 3e-26 Identities = 123/482 (25%), Positives = 170/482 (35%), Gaps = 120/482 (24%) Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCV-KPG--LCRCKPGFFGAHC 86 CV + + +C G+ E I C D CQ D C+ K G C C PGF G HC Sbjct: 433 CVNTDGAFHCECLKGYAGPRCEMDINECHS-DPCQNDATCLDKIGGFTCLCMPGFKGVHC 491 Query: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCEF--------PCACG 136 +C +S PC +GQC C C G C+ PC G Sbjct: 492 ELEIN------EC-QSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNG 544 Query: 137 PHGRCDPATGVCHCEPGWWSSTCRR------PCQCNTAAARCEQATGACVCKPGWWGRRC 190 P C C G+ C P C+ + + C+C PG+ G C Sbjct: 545 AKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAIC 604 Query: 191 SFRCN-CHGSPCEQDSG--------RCACRPGWWGPECQQQCE------CVRGRCSAASG 235 S + + C+ SPC D +C C+PG G C+ + C+ G C Sbjct: 605 SDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGIN 664 Query: 236 E--CTCPPGFRGARCEL--------PCPAGS------HGVQCAHSCGRCKHNEPCSPDTG 279 C C PGF G RC + PC G+ +G +C C H+ C Sbjct: 665 RYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCI--CPEGPHHPSCYSQVN 722 Query: 280 SCES-------CEPGWNGTQCQQPCLPGTFGESCE---QQCPH--CRHGEACEP-DTGHC 326 C S C G +G +C C G G +CE +C C++G C+ G+ Sbjct: 723 ECLSNPCIHGNCTGGLSGYKCL--CDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780 Query: 327 QRCDPGWLGPRCE--------DPCPT-GTF----------------GEDCGSTCPTCVQG 361 C G+ G C+ +PC GT G++C + C Sbjct: 781 CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN 840 Query: 362 SCDTV----------TGDCVCSAGYWGPSCNA------SCPAGFHG----NNCSVPCECP 401 C+ + C+C+ G+ G C S P HG S CECP Sbjct: 841 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP 900 Query: 402 EG 403 G Sbjct: 901 PG 902 Score = 115 bits (287), Expect = 2e-25 Identities = 128/502 (25%), Positives = 165/502 (32%), Gaps = 123/502 (24%) Query: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPI------CEGPDACQKDEVC 69 G G + H C S P C + ECT + C+ DAC C Sbjct: 95 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDAC-LSHPC 153 Query: 70 VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCE--------PATGACQCQ 121 C F C + GQ D E C G C+ P + CQC Sbjct: 154 ANGSTCTTVANQFSCKCLTGFTGQKCETDVNE---CDIPGHCQHGGTCLNLPGSYQCQCP 210 Query: 122 ADRWGARCE---FPCA---CGPHGRCDPA---TGVCHCEPGWWSSTCRRPCQCNTAAARC 172 G C+ PCA C G C T C+C PG+ STC R + RC Sbjct: 211 QGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNID-DCPNHRC 269 Query: 173 EQA--------TGACVCKPGWWGRRCS---FRCNCHGSPCEQDSGRCA---------CRP 212 + T C C P W G+ C+ C + C Q+ G CA C Sbjct: 270 QNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC-QNGGTCANRNGGYGCVCVN 328 Query: 213 GWWGPECQQQC-ECVRGRCS--------AASGECTCPPGFRGARCEL------------- 250 GW G +C + +C C+ AS C CP G G C L Sbjct: 329 GWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388 Query: 251 -------------PCPAGSHGVQCAHSCGRC--KHNEPCSPDTGSCESCEPGWNGTQCQQ 295 CP G G C C ++ PC G C + + ++ C+ Sbjct: 389 LCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCE-HAGKCVNTDGAFH---CE- 443 Query: 296 PCLPGTFGESCEQQCPHCRHGEACEPDT-------GHCQRCDPGWLGPRCEDPCPTGTFG 348 CL G G CE C H + C+ D G C PG+ G CE Sbjct: 444 -CLKGYAGPRCEMDINEC-HSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI------ 495 Query: 349 EDCGSTCPTCVQGSC-DTVTG-DCVCSAGYWGPSC-----NASCPAGFHGNNC-----SV 396 +C S P G C D V C+C G+ GP C + S +G C Sbjct: 496 NECQSN-PCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGY 554 Query: 397 PCECPEG----LCHPVSGSCQP 414 C+C G LC +C P Sbjct: 555 ECQCATGFTGVLCEENIDNCDP 576 Score = 112 bits (279), Expect = 2e-24 Identities = 121/469 (25%), Positives = 161/469 (34%), Gaps = 112/469 (23%) Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVK-PGL--CRCKPGFFGAHC 86 C + +C G+ + E + C+ P CQ C+ PG C+C GF G +C Sbjct: 159 CTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYC 218 Query: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPA---TGACQCQADRWGARCEFPCACGPHGRCDP 143 S + P C S PC G C T C C G+ CE P+ RC Sbjct: 219 DS-----LYVP-CAPS-PCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQN 271 Query: 144 A--------TGVCHCEPGWWSSTCR--------RPCQCNTAAARCEQATG-ACVCKPGWW 186 T C C P W C +P C + G CVC GW Sbjct: 272 GGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS 331 Query: 187 GRRCS-------FRCNCHGSPC--EQDSGRCACRPGWWGPECQQQCECVRGRC------- 230 G CS F GS C S C C G G C C+ C Sbjct: 332 GDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCD 391 Query: 231 -SAASGE--CTCPPGFRGARC----------------------------ELPCPAGSHGV 259 + +G+ CTCP G++GA C C G G Sbjct: 392 TNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGP 451 Query: 260 QCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCR----- 314 +C C H++PC D +C G C C+PG G CE + C+ Sbjct: 452 RCEMDINEC-HSDPCQNDA----TCLDKIGGFTCL--CMPGFKGVHCELEINECQSNPCV 504 Query: 315 -HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS--CDTVTG-DC 370 +G+ + C PG+ GP C+ +DC ST C+ G+ D G +C Sbjct: 505 NNGQCVDKVNRFQCLCPPGFTGPVCQIDI------DDCSST--PCLNGAKCIDHPNGYEC 556 Query: 371 VCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGS----CQPG 415 C+ G+ G C + +NC P C G C S C PG Sbjct: 557 QCATGFTGVLCEENI------DNCD-PDPCHHGQCQDGIDSYTCICNPG 598 Score = 112 bits (279), Expect = 2e-24 Identities = 120/486 (24%), Positives = 168/486 (34%), Gaps = 122/486 (25%) Query: 25 KGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDA-----------CQKDEVCVKPG 73 K + CV ++ C +GW C +P A CQ VC+ G Sbjct: 1073 KNKGTCVQKKAESQCLCPSGWA--GAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130 Query: 74 ---LCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGAR 128 C+C G+ G++C + +C + PC C G C+C G Sbjct: 1131 NTHYCQCPLGYTGSYCEEQLD------ECASN-PCQHGATCSDFIGGYRCECVPGYQGVN 1183 Query: 129 CEF--------PCACGPHGRCDPATG--VCHCEPGWWS-------STCRRPCQCNTAAAR 171 CE+ PC G G C C C PG C R C Sbjct: 1184 CEYEVDECQNQPCQNG--GTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQC 1241 Query: 172 CEQATG-ACVCKPGWWGRRCSFRCN-CHGSPCEQDSGR----------CACRPGWWGPEC 219 ++ G +C C PG+ G RC N C +PC + C CR + G C Sbjct: 1242 MDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC 1301 Query: 220 QQ------QCECVRG-RCSAASGE-----CTCPPGFRGARCELPCPAGS--HGVQCAHSC 265 + Q C+ G C+ AS C CPPGF GARC+ C G QC H+ Sbjct: 1302 ETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTA 1361 Query: 266 -------------------GRCKHNEPCSPDTG----SCESCEPGWNGTQCQ-QPCLPGT 301 C+H C P SC+ C P ++G++C+ P T Sbjct: 1362 SGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQ-CAPPFSGSRCELYTAPPST 1420 Query: 302 FGESCEQQ----------CPHCRHGEACEPDTGHCQ-RCDPGWLGPRCEDPCPTGTF-GE 349 +C Q C + AC+ D G C + W C P P + Sbjct: 1421 PPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPW--ANCSSPLPCWDYINN 1478 Query: 350 DCGSTCPT--CV------QGSCDTVTGDCVCSAGYWGPSCNASC---PAGFHGNNCSVPC 398 C C T C+ QG+ T D C+ + C+ C G+ G +C+ Sbjct: 1479 QCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCA--A 1536 Query: 399 ECPEGL 404 + PE L Sbjct: 1537 DQPENL 1542 Score = 108 bits (269), Expect = 3e-23 Identities = 118/413 (28%), Positives = 161/413 (38%), Gaps = 108/413 (26%) Query: 58 EGPDACQKDEVCVK----PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEP 113 +G + C + +CV G C+C GF G +C R P C ++ +C+ Sbjct: 30 DGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDP-------CEKN-------RCQN 75 Query: 114 ATGACQCQADRWGARCEFPCACGPHGR-CDPATGVCHCEPGWWSSTCRRPCQCNTAAARC 172 G C QA A C CA G G C +T P + S RPC Sbjct: 76 G-GTCVAQAMLGKATCR--CASGFTGEDCQYSTS----HPCFVS----RPCLNGGTCHML 124 Query: 173 EQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSG--------RCACRPGWWGPECQQQC- 223 + T C C+ G+ G+ C + C PC S C C G+ G +C+ Sbjct: 125 SRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVN 184 Query: 224 EC-VRGRCS--------AASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPC 274 EC + G C S +C CP GF G C+ S V CA S PC Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCD------SLYVPCAPS--------PC 230 Query: 275 SPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQ---QCPH--CRHGEACEP--DTGHCQ 327 + G+C + G +C CLPG G +CE+ CP+ C++G C +T +C Sbjct: 231 -VNGGTCR--QTGDFTFECN--CLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNC- 284 Query: 328 RCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQ-GSCDTVTG--DCVCSAGYWGPSCN-- 382 RC P W G C + ++C C G+C G CVC G+ G C+ Sbjct: 285 RCPPQWTGQFCTEDV------DECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSEN 338 Query: 383 ------ASCPAGFHGNNC-----SVPCECPEG----LCH----PVSGSCQPGS 416 ASC G+ C S C CPEG LCH +S C G+ Sbjct: 339 IDDCAFASCTP---GSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388 Score = 104 bits (260), Expect = 3e-22 Identities = 101/385 (26%), Positives = 138/385 (35%), Gaps = 88/385 (22%) Query: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRE--SCPCHPHGQCEPATGA--CQCQADRWGARCE 130 C C G+ G +C D E S PC G C+ C C+ G C+ Sbjct: 743 CLCDAGWVGINCEV---------DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ 793 Query: 131 F---PCACGP---HGRC-DPATG-VCHCEPGWWSSTCRR---PCQCNTA--AARCEQATG 177 CA P G C D +G CHC + C+ PC N AA C+++ Sbjct: 794 VNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPN 853 Query: 178 ----ACVCKPGWWGRRCSFRCN-CHGSPC--------EQDSGRCACRPGWWGPECQQQC- 223 C+C PGW G+RC+ + C PC Q S C C PG+ G +C++ Sbjct: 854 FESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDID 913 Query: 224 ECVRGRCSAASG--------ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCS 275 +C+ C C C PGF G +C+ +C CK+ CS Sbjct: 914 DCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMN------ECLSE--PCKNGGTCS 965 Query: 276 PDTGSCE-SCEPGWNGTQCQQ--------------PCLPGTFGESCEQQCPHCRHGEACE 320 S C+ G++G C+ C+ G SC CP G C Sbjct: 966 DYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSC--LCPVGFTGSFCL 1023 Query: 321 PDTGHCQ--------RCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVC 372 + C C G RC CP G G++C + C + C G CV Sbjct: 1024 HEINECSSHPCLNEGTCVDGLGTYRCS--CPLGYTGKNCQTLVNLCSRSPCKN-KGTCVQ 1080 Query: 373 SAGYWGPSCNASCPAGFHGNNCSVP 397 CP+G+ G C VP Sbjct: 1081 KKA----ESQCLCPSGWAGAYCDVP 1101 >gi|38788416 laminin, alpha 1 precursor [Homo sapiens] Length = 3075 Score = 129 bits (325), Expect = 9e-30 Identities = 113/409 (27%), Positives = 154/409 (37%), Gaps = 108/409 (26%) Query: 75 CRCKPGFFGAHCSSRCPGQY------WGPDCRESCPCHPHGQCEPATGAC-QCQADRWGA 127 C C G+ G C S G Y +G C + C CH H G C C + G Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGIC-QPCECHGHAAECNVHGVCIACAHNTTGV 767 Query: 128 RCEF------------------PCACGPHGRCDPATGVCH-----------CEPGWWSST 158 CE PCAC + + CH C PG+ + Sbjct: 768 HCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAW 827 Query: 159 CRR-----------------PCQCN-----TAAARCEQATGACVCKPGWWGRRCSFRCNC 196 C R PC C+ + A C+ TG C+ G N Sbjct: 828 CERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLG----------NT 877 Query: 197 HGSPCEQDSGRCACRPGWWGPECQQQ----CEC-VRGR----CSAASGECTCPPGFRGAR 247 G+ CE+ C G++G + CEC V+G C +G C C P G + Sbjct: 878 DGAHCER------CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQ 931 Query: 248 CELPCPAGSHGVQCAHSCGRCKHNEPCS-----PDTGSCESCEPGWNGTQCQQPCLPGTF 302 C+ C G +G+ H C C + S D G C C PG G +C + C G + Sbjct: 932 CD-QCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCH-CVPGVAGKRCDR-CAHGFY 988 Query: 303 ----GESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTC 358 G CPH ++ C+P+TG C C P G +CE+ C G +G D C C Sbjct: 989 AYQDGSCTPCDCPHTQN--TCDPETGECV-CPPHTQGVKCEE-CEDGHWGYDAEVGCQAC 1044 Query: 359 ---VQGS----CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC 400 + GS CD VTG C C + + G +C+ C G+ VPC+C Sbjct: 1045 NCSLVGSTHHRCDVVTGHCQCKSKFGGRACD-QCSLGYRDFPDCVPCDC 1092 Score = 115 bits (288), Expect = 2e-25 Identities = 102/342 (29%), Positives = 128/342 (37%), Gaps = 94/342 (27%) Query: 77 CKPGFFGAHCSSRCPGQYWGPDCR-ESC-PCH--------PHGQCEPATGAC-QCQADRW 125 C PG+ GA C G Y P ESC PC G C+ TG C +C + Sbjct: 819 CAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTD 878 Query: 126 GARCEF----------------PCAC---GPHGR-CDPATGVCHCEPGWWSSTCR----- 160 GA CE C C G H C TG+C C+P C Sbjct: 879 GAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHG 938 Query: 161 ----------RPCQCNTAAARCEQAT--GACVCKPGWWGRRCSFRCNCHGSPCEQDSGRC 208 RPC C+ A + + T G C C PG G+RC RC HG QD Sbjct: 939 YYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCD-RC-AHGFYAYQDG--- 993 Query: 209 ACRPGWWGPECQQQCEC--VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG 266 +C P C+C + C +GEC CPP +G +CE C G G C Sbjct: 994 SCTP----------CDCPHTQNTCDPETGECVCPPHTQGVKCE-ECEDGHWGYDAEVGCQ 1042 Query: 267 RC------KHNEPCSPDTGSCESCEPGWNGTQCQQ------------PC---LPGTFGES 305 C + C TG C+ C+ + G C Q PC L GT G++ Sbjct: 1043 ACNCSLVGSTHHRCDVVTGHCQ-CKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDA 1101 Query: 306 CEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTF 347 C + C C +TG C C GP+C + C GTF Sbjct: 1102 CNLEQGLC----GCVEETGACP-CKENVFGPQCNE-CREGTF 1137 Score = 80.9 bits (198), Expect = 5e-15 Identities = 87/315 (27%), Positives = 113/315 (35%), Gaps = 92/315 (29%) Query: 30 CVASSPSAELQCCAGWRQKD----QECTIPICEGPDACQKDEVC-VKPGLCRCKPGFFGA 84 C+ ++ A + CA D + C CE VC ++ GLC CKP G Sbjct: 873 CLGNTDGAHCERCADGFYGDAVTAKNCRA--CECHVKGSHSAVCHLETGLCDCKPNVTGQ 930 Query: 85 HCSSRCPGQYWGPDCRESC-PCHPHGQCEPA---------TGACQCQADRWGARCE---- 130 C +C Y+G D C PC+ C A G C C G RC+ Sbjct: 931 QC-DQCLHGYYGLDSGHGCRPCN----CSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAH 985 Query: 131 ----------FPCACGPH--GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGA 178 PC C PH CDP TG C C P +T +CE+ Sbjct: 986 GFYAYQDGSCTPCDC-PHTQNTCDPETGECVCPP-------------HTQGVKCEE---- 1027 Query: 179 CVCKPGWWGRRCSF---RCNCH--GSP---CEQDSGRCACRPGWWGPECQQQCECVRGRC 230 C+ G WG CNC GS C+ +G C C+ + G C Q Sbjct: 1028 --CEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQ--------- 1076 Query: 231 SAASGECTCPPGFRGARCELPCPA---GSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPG 287 C G+R +PC G+ G C G C C +TG+C C+ Sbjct: 1077 --------CSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLC----GCVEETGAC-PCKEN 1123 Query: 288 WNGTQCQQPCLPGTF 302 G QC + C GTF Sbjct: 1124 VFGPQCNE-CREGTF 1137 Score = 79.0 bits (193), Expect = 2e-14 Identities = 63/240 (26%), Positives = 82/240 (34%), Gaps = 58/240 (24%) Query: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99 QC G+ D C A + C G C C PG G C RC ++ Sbjct: 934 QCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRC-DRCAHGFYAYQD 992 Query: 100 RESCPC---HPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWS 156 PC H C+P TG C C G +CE CE G W Sbjct: 993 GSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCE------------------ECEDGHWG 1034 Query: 157 STCRRPCQ-CNTAAA-----RCEQATGACVCKPGWWGRRC-----SFR---------CNC 196 CQ CN + RC+ TG C CK + GR C +R C+ Sbjct: 1035 YDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDCDL 1094 Query: 197 HGSP------------CEQDSGRCACRPGWWGPECQQQCECVRGRCS-AASGECTCPPGF 243 G+ C +++G C C+ +GP+C EC G + A C P F Sbjct: 1095 RGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCN---ECREGTFALRADNPLGCSPCF 1151 Score = 77.0 bits (188), Expect = 7e-14 Identities = 65/219 (29%), Positives = 84/219 (38%), Gaps = 49/219 (22%) Query: 237 CTCPPGFRGARCELPCPAGSH---GVQCAHSCGRCK---HNEPCSPDTGSCESCEPGWNG 290 C CP G+ G CE C +G + G+ C C+ H C+ G C +C G Sbjct: 709 CECPQGYTGTSCE-SCLSGYYRVDGILFGGICQPCECHGHAAECNVH-GVCIACAHNTTG 766 Query: 291 TQCQQPCLPGTFGESCEQ---QCPHC---------RHGEACEPDTGH---CQRCDPGWLG 335 C+Q CLPG +GE C C C + G C C PG+ G Sbjct: 767 VHCEQ-CLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSG 825 Query: 336 PRCEDPCPTGTFGE-----------DCGSTCPTCVQGSCDTVTGDCV-CSAGYWGPSCNA 383 CE C G +G DC G CD+VTG+C+ C G C Sbjct: 826 AWCER-CADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCE- 883 Query: 384 SCPAGFHGN-----NCSVPCEC-----PEGLCHPVSGSC 412 C GF+G+ NC CEC +CH +G C Sbjct: 884 RCADGFYGDAVTAKNCRA-CECHVKGSHSAVCHLETGLC 921 Score = 70.1 bits (170), Expect = 8e-12 Identities = 55/198 (27%), Positives = 71/198 (35%), Gaps = 37/198 (18%) Query: 237 CTCPPGFRGARCELPCPAGSHGVQCAHS-------------CGRCKHNEPCSPDTGSCES 283 C CPPG G C+ P G A S C H++ C P+TG C + Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421 Query: 284 CEPGWNGTQCQQPCLPGTFGESCEQQ-------CPH---CRHGEACEPDTGHCQRCDP-- 331 C G C C G +G+ CPH C + H RCD Sbjct: 1422 CGDNTAGDHCDV-CTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACL 1480 Query: 332 -GWLGPRCEDPCPTGTFG--EDCGSTCPTC-------VQGSCDTVTGDCVCSAGYWGPSC 381 G+ G CE C + +G + G +C C V G CD +G CVC G G C Sbjct: 1481 LGYEGKHCER-CSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRC 1539 Query: 382 NASCPAGFHGNNCSVPCE 399 + P V C+ Sbjct: 1540 DECEPRHILMETDCVSCD 1557 Score = 62.4 bits (150), Expect = 2e-09 Identities = 56/203 (27%), Positives = 77/203 (37%), Gaps = 52/203 (25%) Query: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRES-------------CPCHPHGQ-CEPATGAC-Q 119 C C PG G C PG + G S C C+ H C+P TG C Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421 Query: 120 CQADRWGARCEFPCACGPHGRCDPATGVC------HCEPGWWSSTCRRPCQCNTAAARCE 173 C + G C+ C G +G+ + C H P +S TC + RC+ Sbjct: 1422 CGDNTAGDHCDV-CTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDF---RCD 1477 Query: 174 QATGACVCKPGWWGRRCSFRCNC--HGSPCEQDSGRCACRPGWWGPECQQQCEC-----V 226 C G+ G+ C RC+ +G+P + G C Q+C+C V Sbjct: 1478 ------ACLLGYEGKHCE-RCSSSYYGNP-QTPGGSC------------QKCDCNPHGSV 1517 Query: 227 RGRCSAASGECTCPPGFRGARCE 249 G C SG+C C G G RC+ Sbjct: 1518 HGDCDRTSGQCVCRLGASGLRCD 1540 Score = 55.1 bits (131), Expect = 3e-07 Identities = 65/240 (27%), Positives = 78/240 (32%), Gaps = 65/240 (27%) Query: 222 QCECVRGRCSAASGECTCP--------PGF--RGARCELPCPAGSHGVQCAHSCGRCKHN 271 QC+C C + C CP PG G CE C + C ++ Sbjct: 289 QCQCEHNTCGESCNRC-CPGYHQQPWRPGTVSSGNTCE--------ACNCHNKAKDCYYD 339 Query: 272 EPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQC-----PHC---RHGEACEPDT 323 E + S + G C CL T G +CE PH E C P Sbjct: 340 ESVAKQKKSLNTAGQFRGGGVCIN-CLQNTMGINCETCIDGYYRPHKVSPYEDEPCRP-- 396 Query: 324 GHCQRCDP-GWLGPRC----------------EDPCPTGTFGEDCG------STCPTCVQ 360 C CDP G L C + PC G GE C PTCV Sbjct: 397 --CN-CDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVS 453 Query: 361 GSCDTV--------TGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSC 412 C+ V TG CVC G +C+ C GF+ P C E C VS C Sbjct: 454 CGCNPVGSASDEPCTGPCVCKENVEGKACD-RCKPGFYNLKEKNPRGCSECFCFGVSDVC 512 Score = 47.4 bits (111), Expect = 6e-05 Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 21/98 (21%) Query: 71 KPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQC--EPATGACQCQADRWGAR 128 +PG C CK G+ G C RC Y SC C+P G EP TG C C+ + G Sbjct: 423 QPGQCPCKEGYTGEKC-DRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKA 481 Query: 129 CEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCN 166 C+ C+PG+++ + P C+ Sbjct: 482 CD------------------RCKPGFYNLKEKNPRGCS 501 Score = 46.6 bits (109), Expect = 1e-04 Identities = 59/261 (22%), Positives = 77/261 (29%), Gaps = 96/261 (36%) Query: 56 ICEG-PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPG---QYWGP------DCRESCPC 105 IC G +C DE K C+C+ G C+ CPG Q W P + E+C C Sbjct: 271 ICYGHASSCPWDET-TKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329 Query: 106 H--------------------PHGQCEPATGACQCQADRWGARCEF-------------- 131 H GQ C + G CE Sbjct: 330 HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPY 389 Query: 132 ------PCACGPHGRCDPA---------------TGVCHCEPGWWSSTCRR--------- 161 PC C P G G C C+ G+ C R Sbjct: 390 EDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYP 449 Query: 162 ---PCQCN-TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGP 217 C CN +A E TG CVCK N G C++ C+PG++ Sbjct: 450 TCVSCGCNPVGSASDEPCTGPCVCKE-----------NVEGKACDR------CKPGFYNL 492 Query: 218 ECQQQCECVRGRCSAASGECT 238 + + C C S C+ Sbjct: 493 KEKNPRGCSECFCFGVSDVCS 513 Score = 45.8 bits (107), Expect = 2e-04 Identities = 55/235 (23%), Positives = 79/235 (33%), Gaps = 57/235 (24%) Query: 226 VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRC---KHNEPCSPDTGS-- 280 V G C +CP + + C + C SC RC H +P P T S Sbjct: 266 VGGMCICYGHASSCPWDETTKKLQCQCEHNT----CGESCNRCCPGYHQQPWRPGTVSSG 321 Query: 281 --CESCEPGWNGTQCQQPCLPGTFGESCEQQ------CPHCRHGEAC----EPDTG-HCQ 327 CE+C C + ES +Q R G C + G +C+ Sbjct: 322 NTCEACN-------CHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCE 374 Query: 328 RCDPGW-----LGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDT------VTGDCVCSAGY 376 C G+ + P ++PC + GS C++ + G C C GY Sbjct: 375 TCIDGYYRPHKVSPYEDEPCRPCNC-DPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGY 433 Query: 377 WGPSCN------------ASC---PAGFHGNN-CSVPCECPEGLCHPVSGSCQPG 415 G C+ SC P G + C+ PC C E + C+PG Sbjct: 434 TGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRCKPG 488 >gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] Length = 2765 Score = 129 bits (324), Expect = 1e-29 Identities = 107/393 (27%), Positives = 146/393 (37%), Gaps = 101/393 (25%) Query: 60 PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ 119 P C + CV G+C C PGF GA C+ + +CP G + + G CQ Sbjct: 577 PRNCHGNGECVS-GVCHCFPGFLGADCA------------KAACPVLCSGNGQYSKGTCQ 623 Query: 120 CQADRWGARCEFPC------ACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAARC 172 C + GA C+ P +CG HG C G C C G+ C C T ++ Sbjct: 624 CYSGWKGAECDVPMNQCIDPSCGGHGSC--IDGNCVCSAGYKGEHCEEVDCLDPTCSSHG 681 Query: 173 EQATGACVCKPGWWGRRCSF-------RCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC 225 G C+C PGW G C +C+ HG+ D+G C+C P W GP+C + Sbjct: 682 VCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYL-PDTGLCSCDPNWMGPDCSVEV-- 738 Query: 226 VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCE 285 C + C G+HGV +C CE Sbjct: 739 ----------------------CSVDC--GTHGVCIGGAC-----------------RCE 757 Query: 286 PGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCE-DPCPT 344 GW G C Q C +C HG C+ G C+ C GW G C D CP Sbjct: 758 EGWTGAACDQ--------RVCHPRC--IEHG-TCK--DGKCE-CREGWNGEHCTIDGCP- 802 Query: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL 404 D + C G + CVC G+ GP CN + N + +GL Sbjct: 803 -----DLCNGNGRCTLGQ---NSWQCVCQTGWRGPGCNVAMETSCADNKDNE----GDGL 850 Query: 405 CHPVSGSCQPGSGSRDTALIAGSLVPLLLLFLG 437 + C S +++ L GS PL ++ G Sbjct: 851 VDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQG 883 Score = 108 bits (269), Expect = 3e-23 Identities = 81/250 (32%), Positives = 99/250 (39%), Gaps = 43/250 (17%) Query: 40 QCCAGWRQKDQECTIPICEGPD-ACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPD 98 QC +GW K EC +P+ + D +C C+ G C C G+ G HC D Sbjct: 623 QCYSGW--KGAECDVPMNQCIDPSCGGHGSCID-GNCVCSAGYKGEHCEE--------VD 671 Query: 99 CRESCPCHPHGQCEPATGACQCQADRWGARCEF-----PCACGPHGRCDPATGVCHCEPG 153 C + C HG C G C C G CE P C HG P TG+C C+P Sbjct: 672 CLDPT-CSSHGVC--VNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPN 728 Query: 154 WWSSTCRRPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCHGSPCEQDSGRC 208 W C GAC C+ GW G R C RC HG+ C+ G+C Sbjct: 729 WMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGT-CK--DGKC 785 Query: 209 ACRPGWWGPECQ-QQCECV---RGRCSAA--SGECTCPPGFRGARCELPCPAGSHGVQCA 262 CR GW G C C + GRC+ S +C C G+RG C V Sbjct: 786 ECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGC---------NVAME 836 Query: 263 HSCGRCKHNE 272 SC K NE Sbjct: 837 TSCADNKDNE 846 >gi|55770876 notch4 preproprotein [Homo sapiens] Length = 2003 Score = 127 bits (319), Expect = 4e-29 Identities = 126/448 (28%), Positives = 163/448 (36%), Gaps = 99/448 (22%) Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVK---PGLCRCKPGFFGAHC 86 C S+ S C +GW E + C C C+ C C PG G C Sbjct: 332 CQNSAGSFHCVCVSGWGGTSCEENLDDCIAA-TCAPGSTCIDRVGSFSCLCPPGRTGLLC 390 Query: 87 SSRCPGQYWGPDCRESCPCHPHGQCE--PATGA--CQCQADRWGARC-----------EF 131 D S PCH QC P TG+ C CQ G C + Sbjct: 391 HLE--------DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQG 442 Query: 132 PCACGPHGRC--DPATGVCHCEPGWWSSTCR--------RPCQCNTAAARCEQATGACVC 181 P C G C P + C C PG+ S C +PC + AT C+C Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDL-LATFHCLC 501 Query: 182 KPGWWGRRCSFRCN-CHGSPCEQDSG--------RCACRPGWWGPECQQQCECVRGRCSA 232 PG G+ C N C +PC + +C C PG+ G C++ + R A Sbjct: 502 PPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCA 561 Query: 233 ASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCES--------C 284 G+C PG +C LP G G +C C ++PC P SC C Sbjct: 562 NGGQCQDQPGAFHCKC-LP---GFEGPRCQTEVDECL-SDPC-PVGASCLDLPGAFFCLC 615 Query: 285 EPGWNGTQCQQP-CLPGTF--GESCEQQ-------CPHCRHG-----EACEPDTGHCQR- 328 G+ G C+ P C P + C+ Q CP G + C GHCQR Sbjct: 616 PSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS 675 Query: 329 ---CDPGWLGPRCEDPCPTGTFGEDC--GSTCPTCVQGSCDTVTGDCVCSAGYWGPSCN- 382 CD GW GP CE G C G TC G +C C GY GP+C+ Sbjct: 676 SCVCDVGWTGPECEAEL-GGCISAPCAHGGTCYPQPSGY------NCTCPTGYTGPTCSE 728 Query: 383 --ASCPAG--FHGNNCSVP-----CECP 401 +C +G +G +C+ C CP Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCP 756 Score = 126 bits (316), Expect = 9e-29 Identities = 133/461 (28%), Positives = 161/461 (34%), Gaps = 120/461 (26%) Query: 52 CTIPICEGPDACQKDE------VCVKPGLCRCKPGFFGAHCSS-----RCPGQYWGPDCR 100 CT P CQ C G C +PG F C+ RC G+ P C Sbjct: 753 CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL-RPSCA 811 Query: 101 ESCPCHPHGQCE--PATGACQCQADRWGARCEF--------PCACGPHGRCDPATGVCHC 150 +S PC C+ P C C G C+ PC H + C C Sbjct: 812 DS-PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLC 870 Query: 151 EPGWWSSTCRRPCQ-CNTAA--------ARCEQATGACV---------CKPGWWGRRCSF 192 GW C P C AA + C G CV C PG+ G C Sbjct: 871 LQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNG-GLCVDSGPSYFCHCPPGFQGSLCQD 929 Query: 193 RCN-CHGSPCE-------QDSGR-CACRPGWWGPECQQQCECVR-------GRCSAASG- 235 N C PC+ Q SG C C PG+ G C ++ + + G C+ G Sbjct: 930 HVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGG 989 Query: 236 -ECTCPPGFRGARCE--------LPC-PAGS---HGV------QC--AHSCGRCK----- 269 C CPPGF G RCE PC P G+ H + QC H+ C+ Sbjct: 990 FHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP 1049 Query: 270 -HNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCP-----HCRHGEAC--EP 321 H++PC G+CE+ G C C G G +C + P HC HG C P Sbjct: 1050 CHSQPCFHG-GTCEATAGSPLGFICH--CPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP 1106 Query: 322 DTGHCQRCD--PGWLGPRC-EDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWG 378 G RC G+ GP C P P G CG P GSC TG G Sbjct: 1107 KPGFPPRCACLSGYGGPDCLTPPAPKG-----CGPPSPCLYNGSCSETTG-------LGG 1154 Query: 379 PSCNASCPAGFHGNNCSVP----CECPEGLCHPVSGSCQPG 415 P SCP G C P CE G G+C G Sbjct: 1155 PGFRCSCPHSSPGPRCQKPGAKGCEGRSG-----DGACDAG 1190 Score = 120 bits (302), Expect = 4e-27 Identities = 123/442 (27%), Positives = 152/442 (34%), Gaps = 111/442 (25%) Query: 57 CEGPDACQKDEVCVKPG-----------------------LCRCKPGFFGAHCSSR---- 89 C+ PD CQ ++C G LC C PGF G C ++ Sbjct: 62 CQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDP 121 Query: 90 CPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEF-------PCACGPHGRCD 142 CP + C + CH P C C G +C+ PC G Sbjct: 122 CPPSF----CSKRGRCHIQASGRP---QCSCMPGWTGEQCQLRDFCSANPCVNGGVCLAT 174 Query: 143 PATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCE 202 CHC PG+ C R C Q G C SF+C C P Sbjct: 175 YPQIQCHCPPGFEGHACERDVN------ECFQDPGPCPKGTSCHNTLGSFQCLC---PVG 225 Query: 203 QDSGRCACRPGWWGPE-CQQQCEC-VRGRCSAASGECTCPPGFRGARCEL-PCPAGSHGV 259 Q+ RC R G P C C + + C CPPGF G CE+ P SH Sbjct: 226 QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH-- 283 Query: 260 QCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQ-CPHCRHGEA 318 QC + G C+ DT +C C W G C + + CE Q PHCR+G Sbjct: 284 QCQNG-GTCQD----GLDTYTC-LCPETWTGWDCSEDV------DECETQGPPHCRNGGT 331 Query: 319 CEPDTG--HCQRCDPGWLGPRCEDP-------------------------CPTGTFGEDC 351 C+ G HC C GW G CE+ CP G G C Sbjct: 332 CQNSAGSFHCV-CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390 Query: 352 -------GSTCPTCVQGSCDTVTGD--CVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE 402 C Q S + +TG C+C GY GP+C+ PCE Sbjct: 391 HLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCE-HG 449 Query: 403 GLCHPVSGS----CQPG-SGSR 419 G C GS C PG +GSR Sbjct: 450 GSCLNTPGSFNCLCPPGYTGSR 471 Score = 116 bits (290), Expect = 1e-25 Identities = 146/540 (27%), Positives = 179/540 (33%), Gaps = 145/540 (26%) Query: 58 EGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRE------SCPCHPHGQC 111 E D C+ C G C+ +PG F HC +C + GP C+ S PC C Sbjct: 550 EDIDECRSSP-CANGGQCQDQPGAF--HC--KCLPGFEGPRCQTEVDECLSDPCPVGASC 604 Query: 112 EPATGA--CQCQADRWGARCEFP-CA---CGPHGRC----DPATGVCH-----CEPGWWS 156 GA C C + G CE P CA C P C D A +C C P + Sbjct: 605 LDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDN 664 Query: 157 STC------RRPCQCNTA--AARCEQATGACV--------------------CKPGWWGR 188 TC R C C+ CE G C+ C G+ G Sbjct: 665 CTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGP 724 Query: 189 RCSFRCN-CHGSPCEQDSG--------RCACRPGWWGPECQQQCE-CVRGRC-------- 230 CS CH PC C C P GP+CQ + CV C Sbjct: 725 TCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVN 784 Query: 231 SAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPC--SPDTGSCESCEPGW 288 + C C GF+G RCE G CA S C++ C SP C C G+ Sbjct: 785 RPGTFSCLCAMGFQGPRCE-----GKLRPSCADS--PCRNRATCQDSPQGPRC-LCPTGY 836 Query: 289 NGTQCQQPCLPGTFGESCEQQ-CPHCRHGEACEPDTGHCQRCDPGWLGPRCEDP------ 341 G CQ T + C Q+ CP H P + HC C GW GP C P Sbjct: 837 TGGSCQ------TLMDLCAQKPCPRNSHCLQTGP-SFHC-LCLQGWTGPLCNLPLSSCQK 888 Query: 342 ------------CPTGTFGEDCGST----CPTCVQGS-CDTVTGDCVCSAGYWGPSCNA- 383 C G D G + CP QGS C C G +C A Sbjct: 889 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQ 948 Query: 384 ------SCPAGFHGNNCSVPCE-CPEGLCHPVSGSCQPGSGSRDTALIAGSLVPLLLLFL 436 C G+ G NCS + C CH G+C P G A G F+ Sbjct: 949 PSGYLCQCAPGYDGQNCSKELDACQSQPCHN-HGTCTPKPGGFHCACPPG--------FV 999 Query: 437 GLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGTLTSLGSTLPCRSLSSHKLPWVTV 496 GL C + D+P T + SL + C+ L H W V Sbjct: 1000 GLR-----CEGDVDECLDQPCHPTGTAA---------CHSLANAFYCQCLPGHTGQWCEV 1045 Score = 111 bits (277), Expect = 3e-24 Identities = 115/415 (27%), Positives = 140/415 (33%), Gaps = 87/415 (20%) Query: 29 VCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCV-KPG--LCRCKPGFFGAH 85 +CV S PS C G++ + + CE CQ C+ +P LC+C PG+ G + Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRP-CQNGATCMAQPSGYLCQCAPGYDGQN 964 Query: 86 CSSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCE--------FPCAC 135 CS D +S PCH HG C P G C C G RCE PC Sbjct: 965 CSKEL-------DACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHP 1017 Query: 136 GPHGRCDPATGV--CHCEPGWWSSTCR---RPCQCNTA--AARCEQATGA-----CVCKP 183 C C C PG C PC CE G+ C C Sbjct: 1018 TGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPK 1077 Query: 184 GWWGRRCSFRC------NCH------GSPCEQDSGRCACRPGWWGPEC-----QQQC--- 223 G+ G CS R +CH SP RCAC G+ GP+C + C Sbjct: 1078 GFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1137 Query: 224 -ECV-RGRCSAASG------ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCS 275 C+ G CS +G C+CP G RC+ P G G +C + Sbjct: 1138 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1197 Query: 276 PDTGSCESCEPG-WNGTQCQQPCLPGTFGESCEQQCP---------HCRHGEACEPDTGH 325 D G C P W G C C QC C AC P + Sbjct: 1198 WDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTP--AY 1255 Query: 326 CQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPS 380 Q C + CE C T G D G C GD WGPS Sbjct: 1256 DQYCHDHFHNGHCEKGCNTAECGWD---------GGDCRPEDGD-----PEWGPS 1296 >gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] Length = 2769 Score = 127 bits (319), Expect = 4e-29 Identities = 99/332 (29%), Positives = 125/332 (37%), Gaps = 62/332 (18%) Query: 60 PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC-RESCPCHPHGQCEPATGAC 118 P C + C+ G C C GF G PDC R SCP G + G C Sbjct: 567 PSNCYGNGDCIS-GTCHCFLGFLG-------------PDCGRASCPVLCSGNGQYMKGRC 612 Query: 119 QCQADRWGARCEFP------CACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171 C + GA C+ P AC HG C TG C C PG+ +C C T + R Sbjct: 613 LCHSGWKGAECDVPTNQCIDVACSNHGTC--ITGTCICNPGYKGESCEEVDCMDPTCSGR 670 Query: 172 CEQATGACVCKPGWWGRRCSF-------RCNCHGSPCEQDSGRCACRPGWWGPECQQQ-- 222 G C C GW G C +C+ HG+ D+G C+C P W G +C + Sbjct: 671 GVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGT-FLPDTGLCSCDPSWTGHDCSIEIC 729 Query: 223 -CECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSC 281 +C G G C C G+ GA C+ + H RC + C G C Sbjct: 730 AADC-GGHGVCVGGTCRCEDGWMGAACD---------QRACHP--RCAEHGTCR--DGKC 775 Query: 282 ESCEPGWNGTQCQQPCLPGTFGESCEQQCPH-CRHGEACEPDTG--HCQRCDPGWLGPRC 338 E C PGWNG C + ++ CP C C D HC C GW G C Sbjct: 776 E-CSPGWNGEHC---TIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCV-CQLGWRGAGC 830 Query: 339 EDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDC 370 + T CG + G D + DC Sbjct: 831 DTSMETA-----CGDSKDNDGDGLVDCMDPDC 857 Score = 115 bits (287), Expect = 2e-25 Identities = 85/311 (27%), Positives = 112/311 (36%), Gaps = 49/311 (15%) Query: 133 CACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF 192 C +G D +G CHC G+ C R + + G C+C GW G C Sbjct: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625 Query: 193 RCN-CHGSPCEQD----SGRCACRPGWWGPECQQQCECVRGRCS----AASGECTCPPGF 243 N C C +G C C PG+ G C ++ +C+ CS GEC C G+ Sbjct: 626 PTNQCIDVACSNHGTCITGTCICNPGYKGESC-EEVDCMDPTCSGRGVCVRGECHCSVGW 684 Query: 244 RGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP------- 296 G CE P A +C + PDTG C SC+P W G C Sbjct: 685 GGTNCETP---------RATCLDQCSGHGTFLPDTGLC-SCDPSWTGHDCSIEICAADCG 734 Query: 297 -----------CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCE-DPCPT 344 C G G +C+Q+ H R E G C+ C PGW G C Sbjct: 735 GHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCE-CSPGWNGEHCTIAHYLD 793 Query: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGN---------NCS 395 E C C + + D CVC G+ G C+ S + +C Sbjct: 794 RVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCM 853 Query: 396 VPCECPEGLCH 406 P C + LCH Sbjct: 854 DPDCCLQPLCH 864 Score = 105 bits (263), Expect = 1e-22 Identities = 78/258 (30%), Positives = 97/258 (37%), Gaps = 52/258 (20%) Query: 41 CCAGWRQKDQECTIPICEGPD-ACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99 C +GW K EC +P + D AC C+ G C C PG+ G C DC Sbjct: 614 CHSGW--KGAECDVPTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEE--------VDC 662 Query: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCA-----CGPHGRCDPATGVCHCEPGW 154 + C G C G C C G CE P A C HG P TG+C C+P W Sbjct: 663 MDP-TCSGRGVC--VRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSW 719 Query: 155 WSSTCRRPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCHGSPCEQDSGRCA 209 C G C C+ GW G R C RC HG+ C G+C Sbjct: 720 TGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGT-CR--DGKCE 776 Query: 210 CRPGWWGPEC----------QQQCECV---RGRCS--AASGECTCPPGFRGARCELPCPA 254 C PGW G C ++ C + GRC+ C C G+RGA C+ Sbjct: 777 CSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCD----- 831 Query: 255 GSHGVQCAHSCGRCKHNE 272 +CG K N+ Sbjct: 832 ----TSMETACGDSKDND 845 >gi|9506545 delta-like 4 protein precursor [Homo sapiens] Length = 685 Score = 122 bits (307), Expect = 1e-27 Identities = 108/403 (26%), Positives = 148/403 (36%), Gaps = 95/403 (23%) Query: 23 DPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDAC-QKDEVCVKPGLCRCKPGF 81 D G +VC P L C GW + C PIC C +++ C KP C C+PG+ Sbjct: 193 DHFGHYVC---QPDGNLSCLPGWT--GEYCQQPICLS--GCHEQNGYCSKPAECLCRPGW 245 Query: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRC 141 G C+ C PH C T C P C C Sbjct: 246 QGRLCNE----------------CIPHNGCRHGT-------------CSTPWQC----TC 272 Query: 142 DPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCN-CHGSP 200 D G C+ T PC+ + Q + C C+PG+ G C + C +P Sbjct: 273 DEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNP 332 Query: 201 C--------EQDSGRCACRPGWWGPECQQ------QCECVRG-----RCSAASGECTCPP 241 C ++D C C PG++G C+ C G R A+ C CPP Sbjct: 333 CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPP 392 Query: 242 GFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGT 301 F G+ CE + CA+ G+C + P + C C PG+ GT C+ Sbjct: 393 NFTGSNCEKKVDRCTSN-PCANG-GQCLNRGP----SRMCR-CRPGFTGTYCE------L 439 Query: 302 FGESCEQQCPHCRHGEAC-EPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQ 360 C + C HG C + + G C G+ G RCE T + C S+ P + Sbjct: 440 HVSDCARN--PCAHGGTCHDLENGLMCTCPAGFSGRRCE----VRTSIDACASS-PCFNR 492 Query: 361 GSC--DTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECP 401 +C D T VC +CP GF G+ C P P Sbjct: 493 ATCYTDLSTDTFVC-----------NCPYGFVGSRCEFPVGLP 524 Score = 90.5 bits (223), Expect = 6e-18 Identities = 86/308 (27%), Positives = 109/308 (35%), Gaps = 76/308 (24%) Query: 180 VCKPGWWGRRCSFRC---NCH-GSPCEQDSGRCACRPGWWGPECQQQ-----CECVRGRC 230 +C ++G CS C N H G Q G +C PGW G CQQ C G C Sbjct: 174 ICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYC 233 Query: 231 SAASGECTCPPGFRGARC------------------ELPCPAGSHGVQCAHSCGRCKHNE 272 S + EC C PG++G C + C G G+ C C H+ Sbjct: 234 SKPA-ECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHS 292 Query: 273 PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPH-----CRHGEAC--EPDTGH 325 PC S + + T C PG G CE + CR+G +C + D H Sbjct: 293 PCKNGATCSNSGQRSYTCT-----CRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYH 347 Query: 326 CQRCDPGWLGPRCE--------DPCPTG------TFGEDCGSTCPTCVQGS-CDTVTGDC 370 C C PG+ G CE PC G G + CP GS C+ C Sbjct: 348 C-LCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRC 406 Query: 371 V---CSAG----YWGPSCNASCPAGFHGNNCSV--------PCECPEGLCHPVSG----S 411 C+ G GPS C GF G C + PC G CH + + Sbjct: 407 TSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPC-AHGGTCHDLENGLMCT 465 Query: 412 CQPGSGSR 419 C G R Sbjct: 466 CPAGFSGR 473 Score = 63.5 bits (153), Expect = 8e-10 Identities = 50/178 (28%), Positives = 63/178 (35%), Gaps = 35/178 (19%) Query: 252 CPAGSHGVQCAHSCGRCKHNEP-----CSPDTGSCESCEPGWNGTQCQQP-CLPGTFGES 305 C +G C+ C K N+ C PD SC PGW G CQQP CL G Sbjct: 175 CSDNYYGDNCSRLCK--KRNDHFGHYVCQPDGNL--SCLPGWTGEYCQQPICLSG----- 225 Query: 306 CEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDT 365 C +Q +C C C PGW G C + P C G+C T Sbjct: 226 CHEQNGYCSKPAEC--------LCRPGWQGRLCNECIPHNG-----------CRHGTCST 266 Query: 366 VTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRDTAL 423 C C G+ G C+ H + C C + +C+PG D L Sbjct: 267 -PWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCEL 323 Score = 40.4 bits (93), Expect = 0.007 Identities = 33/115 (28%), Positives = 41/115 (35%), Gaps = 13/115 (11%) Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC--VKPGL-CRCKPGFFGAHC 86 C+ PS +C G+ E + C + C C ++ GL C C GF G C Sbjct: 417 CLNRGPSRMCRCRPGFTGTYCELHVSDC-ARNPCAHGGTCHDLENGLMCTCPAGFSGRRC 475 Query: 87 SSRCPGQYWGPDCRESCPCHPHGQC----EPATGACQCQADRWGARCEFPCACGP 137 R D S PC C T C C G+RCEFP P Sbjct: 476 EVRT-----SIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLPP 525 >gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] Length = 1590 Score = 122 bits (306), Expect = 1e-27 Identities = 104/352 (29%), Positives = 129/352 (36%), Gaps = 93/352 (26%) Query: 56 ICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPAT 115 IC+ P C K CV P +C+CKPG+ G++C + PDC+ HG+C Sbjct: 1297 ICKYP--CGKSRECVAPNICKCKPGYIGSNCQT----ALCDPDCKN------HGKC-IKP 1343 Query: 116 GACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQA 175 CQC GA C+ HC P PCQ A Sbjct: 1344 NICQCLPGHGGATCDEE----------------HCNP---------PCQHGGTCL----A 1374 Query: 176 TGACVCKPGWWGRRC-SFRCNCH---GSPCEQDSGRCACRPGWWGPECQQQ-CE--CVRG 228 C C G+ G RC + CN H G C C C+PGW+GP C C+ C+ G Sbjct: 1375 GNLCTCPYGFVGPRCETMVCNRHCENGGQC-LTPDICQCKPGWYGPTCSTALCDPVCLNG 1433 Query: 229 RCSAASGECTCPPGFRG-----ARCELPCPAGSHGVQ-----CAHS-CGRCKHNEPCSP- 276 C CP GF G A C PC G H ++ C GR C P Sbjct: 1434 GSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPT 1493 Query: 277 --DTGSCE-----SCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRC 329 + G C SC GW+G +C P C Q+C + GE P H C Sbjct: 1494 CMNGGKCVGPSTCSCPSGWSGKRCNTPI--------CLQKCKN--GGECIAPSICH---C 1540 Query: 330 DPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSC 381 W G RC+ P C P C+ G C C Y G C Sbjct: 1541 PSSWEGVRCQIPI--------CN---PKCLYGGRCIFPNVCSCRTEYSGVKC 1581 Score = 96.7 bits (239), Expect = 8e-20 Identities = 117/421 (27%), Positives = 149/421 (35%), Gaps = 124/421 (29%) Query: 51 ECTIPICEGPDACQKDEVCVK-----PG----LCRCKPGFFGAHCS---SRCP------G 92 E T+ C+ C CV PG LC C PGF G+ C S C G Sbjct: 1175 EVTVKSCD----CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLG 1230 Query: 93 QYWGPDCRESCPCHPHGQCEP-------ATGACQCQADRWGARCEFPC-ACGPHGRCDPA 144 Y SC C P + E ++D+ + E A G P Sbjct: 1231 SYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPT 1290 Query: 145 TGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFR-----CNCHGS 199 +G + C+ PC +R A C CKPG+ G C C HG Sbjct: 1291 SGNAF-------TICKYPC----GKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGK 1339 Query: 200 PCEQDSGRCACRPGWWGPECQQQ-CE--CVRGRCSAASGECTCPPGFRGARCELPCPAGS 256 + + C C PG G C ++ C C G A CTCP GF G RCE Sbjct: 1340 CIKPNI--CQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMV---- 1393 Query: 257 HGVQCAHSCGR-CKHNEPC-SPDTGSCESCEPGW---------------NGTQCQQP--- 296 C R C++ C +PD C+ C+PGW NG C +P Sbjct: 1394 --------CNRHCENGGQCLTPDI--CQ-CKPGWYGPTCSTALCDPVCLNGGSCNKPNTC 1442 Query: 297 -CLPGTFGESCEQQCPH--CRHGEACEPDTGHCQR-----CDPGWLGPRCEDPCPTGTFG 348 C G FGE C+ H C++G GHC R C G+ G R + Sbjct: 1443 LCPNGFFGEHCQNAFCHPPCKNG-------GHCMRNNVCVCREGYTGRRFQK-------- 1487 Query: 349 EDCGSTC-PTCVQGSCDTVTGDCVCSAGYWGPSCNA-----SCPAGFHGNNCSVP--CEC 400 S C PTC+ G C C +G+ G CN C +G C P C C Sbjct: 1488 ----SICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCK---NGGECIAPSICHC 1540 Query: 401 P 401 P Sbjct: 1541 P 1541 Score = 77.4 bits (189), Expect = 5e-14 Identities = 77/287 (26%), Positives = 108/287 (37%), Gaps = 88/287 (30%) Query: 179 CVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPEC----QQQCEC--------- 225 CVC PG+ HGS CE D C P G C+C Sbjct: 1204 CVCLPGF-----------HGSLCEVDISGCQSNPCGLGSYISGFHSYSCDCPPELKVETQ 1252 Query: 226 ----------VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCS 275 V R + + +G + + +G+ C + CG K E + Sbjct: 1253 FVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCG--KSRECVA 1310 Query: 276 PDTGSCESCEPGWNGTQCQQ-------------------PCLPGTFGESC-EQQC-PHCR 314 P+ C+ C+PG+ G+ CQ CLPG G +C E+ C P C+ Sbjct: 1311 PNI--CK-CKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQ 1367 Query: 315 HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGD-CVCS 373 HG C G+ C G++GPRCE C C G C +T D C C Sbjct: 1368 HGGTCL--AGNLCTCPYGFVGPRCETMV--------CNRHCEN--GGQC--LTPDICQCK 1413 Query: 374 AGYWGPSCNASC--PAGFHGNNCSVP--CECPEG---------LCHP 407 G++GP+C+ + P +G +C+ P C CP G CHP Sbjct: 1414 PGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHP 1460 Score = 64.3 bits (155), Expect = 4e-10 Identities = 57/205 (27%), Positives = 77/205 (37%), Gaps = 43/205 (20%) Query: 40 QCCAGWRQKDQECTI--PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGP 97 QC GW + P+C +C KP C C GFFG HC + + P Sbjct: 1411 QCKPGWYGPTCSTALCDPVCLNGGSCN------KPNTCLCPNGFFGEHCQN----AFCHP 1460 Query: 98 DCRESCPCHPHGQCEPATGACQCQADRWGAR-----CEFPCACGPHGRC-DPATGVCHCE 151 PC G C C C+ G R C+ C G G+C P+T C C Sbjct: 1461 ------PCKNGGHC-MRNNVCVCREGYTGRRFQKSICDPTCMNG--GKCVGPST--CSCP 1509 Query: 152 PGWWSSTCRRPCQCNTAAARCEQ-----ATGACVCKPGWWGRRCSFR-CN---CHGSPCE 202 GW C P +C+ A C C W G RC CN +G C Sbjct: 1510 SGWSGKRCNTP----ICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCI 1565 Query: 203 QDSGRCACRPGWWGPECQQQCECVR 227 + C+CR + G +C+++ + R Sbjct: 1566 FPN-VCSCRTEYSGVKCEKKIQIRR 1589 >gi|4557679 jagged 1 precursor [Homo sapiens] Length = 1218 Score = 120 bits (301), Expect = 5e-27 Identities = 140/531 (26%), Positives = 176/531 (33%), Gaps = 170/531 (32%) Query: 41 CCAGWRQKDQECTIPICEGPDACQKD-------EVCVKPGLCRCKPGFFGAHCSSRCPGQ 93 C G + +C G C KD + C+ G C G CS CP Sbjct: 271 CVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCS-NTGPDKYQCS--CPEG 327 Query: 94 YWGPDCR---ESC---PCHPHGQC-EPATG-ACQCQADRWGARCEF------PCACGPHG 139 Y GP+C +C PCH G C E + G C+C G C P C G Sbjct: 328 YSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387 Query: 140 RC-DPATGV-CHCEPGWWSSTCR--------RPCQCNTAAARCEQATGACVCKPGWWGRR 189 C D G C C P W TC+ +PC N + + A+ C C PGW G+ Sbjct: 388 TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPC-VNAKSCKNLIASYYCDCLPGWMGQN 446 Query: 190 CSFRCNCHGSPCEQDSG--------RCACRPGWWGPECQQQC-ECVRGRCSAASG----- 235 C N C+ D+ RC C PG+ G C++ EC C Sbjct: 447 CDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEI 506 Query: 236 ---ECTCPPGFRGARCEL-------------------------PCPAGSHGVQCAHSCGR 267 +C CP GF G C+L CP G C+H Sbjct: 507 NRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDH 566 Query: 268 CKHNEPC-----------SPDT---------------GSCES---------CEPGWNGTQ 292 C+ PC S DT G C+S C G+ GT Sbjct: 567 CR-TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTY 625 Query: 293 CQQPCLPGTFGESCEQQCPHCRHGEAC-EPDTGHCQRCDPGWLGPRCE--------DPCP 343 C + CE CR+G C + + C GW G CE +PC Sbjct: 626 CHENI------NDCESN--PCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCH 677 Query: 344 TG--------TFGEDC-----GSTC---------PTCVQGSCDTVTGD---CVCSAGYWG 378 G F DC G TC TC G GD C+C G+ G Sbjct: 678 NGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEG 737 Query: 379 PSC----NASC-PAGFH-GNNC-----SVPCECPEG----LCHPVSGSCQP 414 +C N+SC P H G C S C C EG +C + C P Sbjct: 738 TTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSP 788 Score = 113 bits (282), Expect = 8e-25 Identities = 118/426 (27%), Positives = 149/426 (34%), Gaps = 103/426 (24%) Query: 41 CCAGWRQKDQECTIPICEGPDACQ-KDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99 C GW EC IC C K C PG CRC+ G+ G +C P P C Sbjct: 220 CMEGWM--GPECNRAICR--QGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIP----HPGC 271 Query: 100 RESCPCHPHGQC-EPATGACQCQADRWGARCEFPC-ACGPHGRC---------DPATGVC 148 HG C EP C C+ + G C+ CG H C P C Sbjct: 272 -------VHGICNEP--WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQC 322 Query: 149 HCEPGWWSSTC---RRPC---QCNTAAARCEQATG-ACVCKPGWWGRRCSFRC------N 195 C G+ C C C+ + E + G C C PGW G CS N Sbjct: 323 SCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 382 Query: 196 C-HGSPCEQ--DSGRCACRPGWWGPECQ---QQCE---CVRGRCS---AASGECTCPPGF 243 C HG C+ + +C C P W G CQ +CE CV + AS C C PG+ Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGW 442 Query: 244 RGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFG 303 G C+ + G+C+++ SC NG +C C PG G Sbjct: 443 MGQNCD---------ININDCLGQCQND----------ASCRDLVNGYRC--ICPPGYAG 481 Query: 304 ESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSC 363 + CE+ C + GHCQ R + CPTG G C C C Sbjct: 482 DHCERDIDECASNPCL--NGGHCQN-----EINRFQCLCPTGFSGNLCQLDIDYCEPNPC 534 Query: 364 DTVTGDCVCSAGYWGPSCNASCPAGFHGNNCS--------VPCECPEGLCHPVSGSCQPG 415 ++ Y+ CP + G NCS PCE V SC Sbjct: 535 QNGAQCYNRASDYF-----CKCPEDYEGKNCSHLKDHCRTTPCE--------VIDSCTVA 581 Query: 416 SGSRDT 421 S DT Sbjct: 582 MASNDT 587 Score = 107 bits (266), Expect = 6e-23 Identities = 113/449 (25%), Positives = 146/449 (32%), Gaps = 139/449 (30%) Query: 41 CCAGWRQKDQECTIPICEGPDACQKDEVC---VKPGLCRCKPGFFGAHCSSR-------- 89 C GW Q C I I + CQ D C V C C PG+ G HC Sbjct: 438 CLPGWM--GQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNP 495 Query: 90 -----------------CPGQYWGPDCR------ESCPCHPHGQC--EPATGACQCQADR 124 CP + G C+ E PC QC + C+C D Sbjct: 496 CLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 555 Query: 125 WGARCEF--------PC-------------------------ACGPHGRCDPATG---VC 148 G C PC CGPHG+C +G C Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615 Query: 149 HCEPGWWSSTCRR---PCQCNTA--AARCEQATGA--CVCKPGWWGRRCSFRCN-CHGSP 200 C G+ + C C+ N C + C+C GW G C N C +P Sbjct: 616 DCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP 675 Query: 201 CEQ--------DSGRCACRPGWWGPECQQ---QCE---CVRGRCSAASGE---CTCPPGF 243 C + C C+ GW G C QC+ C G G+ C CP G+ Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW 735 Query: 244 RGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFG 303 G C + + C H+ G C N ++ +C C+ GW G C Q Sbjct: 736 EGTTCNIARNSSCLPNPC-HNGGTCVVNG----ESFTCV-CKEGWEGPICAQ-------- 781 Query: 304 ESCEQQCPH-CRHGEAC-EPDTGHCQRCDPGWLGPRC--------EDPCPTGTFGEDCGS 353 + PH C + C + D + C PG+ GP C PC G Sbjct: 782 -NTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGA------- 833 Query: 354 TCPTCVQGSCDTVTG-DCVCSAGYWGPSC 381 TCV D + G CVC G+ G C Sbjct: 834 ---TCV----DEINGYRCVCPPGHSGAKC 855 Score = 84.7 bits (208), Expect = 3e-16 Identities = 87/319 (27%), Positives = 115/319 (36%), Gaps = 86/319 (26%) Query: 57 CEGPDACQKDEVC---VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEP 113 CE + C+ C V C C G+ GA+C + DC ++ PCH G C Sbjct: 633 CES-NPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIN------DCSQN-PCHNGGTCRD 684 Query: 114 ATGA--CQCQADRWGARCEFPCACGPHGRCDPAT----GVCH---------CEPGWWSST 158 C C+ G C +CD AT G C+ C GW +T Sbjct: 685 LVNDFYCDCKNGWKGKTCH-----SRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTT 739 Query: 159 CR---------RPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCN-CHGSPCEQDSG-- 206 C PC N + CVCK GW G C+ N C PC +SG Sbjct: 740 CNIARNSSCLPNPCH-NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPC-YNSGTC 797 Query: 207 -------RCACRPGWWGPECQQQC-ECVRGRCSAASG--------ECTCPPGFRGARCE- 249 RC C PG+ GP+C+ EC C+ + C CPPG GA+C+ Sbjct: 798 VDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQE 857 Query: 250 ---LPC-PAGS---HGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302 PC GS G + C C+ C +C W G +PCL Sbjct: 858 VSGRPCITMGSVIPDGAKWDDDCNTCQ----C---LNGRIACSKVWCG---PRPCL---- 903 Query: 303 GESCEQQCPHCRHGEACEP 321 + C G++C P Sbjct: 904 ---LHKGHSECPSGQSCIP 919 Score = 80.9 bits (198), Expect = 5e-15 Identities = 82/314 (26%), Positives = 104/314 (33%), Gaps = 79/314 (25%) Query: 166 NTAAARCEQATGACVCKPGWWGRRCSFRCNCHGS-----PCEQDSGRCACRPGWWGPE-- 218 NT A E C ++G C+ C C+Q+ G C GW GPE Sbjct: 173 NTGVAHFEYQIRV-TCDDYYYGFGCNKFCRPRDDFFGHYACDQN-GNKTCMEGWMGPECN 230 Query: 219 ---CQQQCECVRGRCSAASGECTCPPGFRGARCE--LPCPAGSHGV-----QCAHSCGRC 268 C+Q C G C G+C C G++G C+ +P P HG+ QC C Sbjct: 231 RAICRQGCSPKHGSCK-LPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCL--CETN 287 Query: 269 KHNEPCSPDTGSCESCEPGWNGTQC--------QQPCLPGTFGESC---EQQC---PHCR 314 + C D C + +P NG C Q C G G +C E C P Sbjct: 288 WGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHN 347 Query: 315 HGEACEPDTGHCQRCDPGWLGPRCE---DPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCV 371 G E G C PGW GP C D C G TC V G CV Sbjct: 348 RGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSH--GGTCQDLVNGF------KCV 399 Query: 372 CSAGYWGPSCN-------------------------ASCPAGFHGNNCSVPCECPEGLCH 406 C + G +C C G+ G NC + + Sbjct: 400 CPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDIN-------IN 452 Query: 407 PVSGSCQPGSGSRD 420 G CQ + RD Sbjct: 453 DCLGQCQNDASCRD 466 >gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] Length = 2699 Score = 119 bits (298), Expect = 1e-26 Identities = 99/337 (29%), Positives = 119/337 (35%), Gaps = 74/337 (21%) Query: 56 ICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPAT 115 + E P C + CV G C C PGF G CS R +CP G + + Sbjct: 515 VVECPRNCHGNGECVS-GTCHCFPGFLGPDCS------------RAACPVLCSGNGQYSK 561 Query: 116 GACQCQADRWGARCEFPCA------CGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTA 168 G C C + G C+ P CG G C G C C G+ +C C Sbjct: 562 GRCLCFSGWKGTECDVPTTQCIDPQCGGRGIC--IMGSCACNSGYKGESCEEADCIDPGC 619 Query: 169 AARCEQATGACVCKPGWWGRRCSF-------RCNCHGSPCEQDSGRCACRPGWWGPECQQ 221 + G C C PGW G C +C+ HG+ Q+SG C C P W GP+C Sbjct: 620 SNHGVCIHGECHCSPGWGGSNCEILKTMCPDQCSGHGTYL-QESGSCTCDPNWTGPDCSN 678 Query: 222 QCECV----RGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPD 277 + V G C G C C G+ G C + H RC + C Sbjct: 679 EICSVDCGSHGVC--MGGTCRCEEGWTGPAC---------NQRACHP--RCAEHGTCK-- 723 Query: 278 TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTG--HCQRCDPGWLG 335 G CE C GWNG C PG C C D HC C PGW G Sbjct: 724 DGKCE-CSQGWNGEHCTIEGCPGL-----------CNSNGRCTLDQNGWHCV-CQPGWRG 770 Query: 336 PRC----EDPCPTGTFGE-----DCGSTCPTCVQGSC 363 C E C E DC C+Q SC Sbjct: 771 AGCDVAMETLCTDSKDNEGDGLIDCMDP-DCCLQSSC 806 Score = 110 bits (275), Expect = 5e-24 Identities = 86/299 (28%), Positives = 112/299 (37%), Gaps = 61/299 (20%) Query: 130 EFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRR 189 E P C +G C +G CHC PG+ C R + + + G C+C GW G Sbjct: 517 ECPRNCHGNGEC--VSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTE 574 Query: 190 CSF-RCNCHGSPCEQDS----GRCACRPGWWGPECQQQCECVRGRCS----AASGECTCP 240 C C C G CAC G+ G C ++ +C+ CS GEC C Sbjct: 575 CDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESC-EEADCIDPGCSNHGVCIHGECHCS 633 Query: 241 PGFRGARCEL---PCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPC 297 PG+ G+ CE+ CP +C + ++GSC +C+P W G C Sbjct: 634 PGWGGSNCEILKTMCP------------DQCSGHGTYLQESGSC-TCDPNWTGPDCS--- 677 Query: 298 LPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPT 357 E C C HG G RC+ GW GP C C C Sbjct: 678 -----NEICSVDCG--SHGVC----MGGTCRCEEGWTGPACNQ--------RACHPRC-- 716 Query: 358 CVQGSCDTVTGDCVCSAGYWGPSCN-ASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPG 415 G+C G C CS G+ G C CP + N C + H V CQPG Sbjct: 717 AEHGTCK--DGKCECSQGWNGEHCTIEGCPGLCNSNG---RCTLDQNGWHCV---CQPG 767 Score = 97.4 bits (241), Expect = 5e-20 Identities = 69/236 (29%), Positives = 92/236 (38%), Gaps = 41/236 (17%) Query: 22 LDPK--GQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKP 79 +DP+ G+ +C+ S C K + C C P C VC+ G C C P Sbjct: 583 IDPQCGGRGICIMGS------CACNSGYKGESCEEADCIDP-GCSNHGVCIH-GECHCSP 634 Query: 80 GFFGAHCS---SRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCA-- 134 G+ G++C + CP Q C HG +G+C C + G C Sbjct: 635 GWGGSNCEILKTMCPDQ-----------CSGHGTYLQESGSCTCDPNWTGPDCSNEICSV 683 Query: 135 -CGPHGRCDPATGVCHCEPGWWSSTC-RRPCQCNTAA-ARCEQATGACVCKPGWWGRRCS 191 CG HG C G C CE GW C +R C A C+ G C C GW G C+ Sbjct: 684 DCGSHGVC--MGGTCRCEEGWTGPACNQRACHPRCAEHGTCKD--GKCECSQGWNGEHCT 739 Query: 192 FR-----CNCHGS-PCEQDSGRCACRPGWWGPECQQQCE--CVRGRCSAASGECTC 239 CN +G +Q+ C C+PGW G C E C + + G C Sbjct: 740 IEGCPGLCNSNGRCTLDQNGWHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDC 795 >gi|110735443 delta-like 1 [Homo sapiens] Length = 723 Score = 117 bits (294), Expect = 3e-26 Identities = 106/377 (28%), Positives = 144/377 (38%), Gaps = 95/377 (25%) Query: 52 CTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQC 111 C++ C D C + G C PG+ G +C+ P C C HG C Sbjct: 188 CSV-FCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTE--------PICLPGCD-EQHGFC 237 Query: 112 EPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAAR 171 + G C+C+ G C+ C PG TC++P QCN Sbjct: 238 DKP-GECKCRVGWQGRYCD----------------ECIRYPGCLHGTCQQPWQCN----- 275 Query: 172 CEQATGACVCKPGWWGRRCSFRCN--CHGSPCE---------QDSGRCACRPGWWGPECQ 220 C+ GW G C+ N H PC+ Q S C+CRPG+ G C+ Sbjct: 276 ---------CQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCE 326 Query: 221 ---QQCE---CVRG-RCSAA--SGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHN 271 +C+ C G C+ S CTCPPGF G CEL + G C + GRC Sbjct: 327 LGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADG-PCFNG-GRCSD- 383 Query: 272 EPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEAC-EPDTGHCQRCD 330 SPD G C G++G C++ + C C +G C + + RC Sbjct: 384 ---SPDGGYSCRCPVGYSGFNCEKKI------DYCSSS--PCSNGAKCVDLGDAYLCRCQ 432 Query: 331 PGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFH 390 G+ G C+D +DC S+ P G+C D C +CP G+ Sbjct: 433 AGFSGRHCDDNV------DDCASS-PCANGGTCRDGVNDFSC-----------TCPPGYT 474 Query: 391 GNNCSVP-CECPEGLCH 406 G NCS P C CH Sbjct: 475 GRNCSAPVSRCEHAPCH 491 >gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [Homo sapiens] Length = 1138 Score = 117 bits (292), Expect = 6e-26 Identities = 58/135 (42%), Positives = 68/135 (50%), Gaps = 9/135 (6%) Query: 210 CRPGWWGPECQQQCE-CVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSC-- 265 C G WGP C ++C C+ G C GEC CPPGF G RCE C G G C C Sbjct: 215 CGAGRWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPG 274 Query: 266 -GRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTG 324 C+ C PD C SC GW G+QCQ+ C PG FG C QC C++G C+ +G Sbjct: 275 ISGCRGLTFCLPDPYGC-SCGSGWRGSQCQEACAPGHFGADCRLQC-QCQNGGTCDRFSG 332 Query: 325 HCQRCDPGWLGPRCE 339 C GW G CE Sbjct: 333 CV--CPSGWHGVHCE 345 Score = 114 bits (286), Expect = 3e-25 Identities = 56/136 (41%), Positives = 69/136 (50%), Gaps = 6/136 (4%) Query: 252 CPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCP 311 C AG G C C C H C G C C PG+ GT+C+Q C G FG+SC++QCP Sbjct: 215 CGAGRWGPGCTKECPGCLHGGVCHDHDGECV-CPPGFTGTRCEQACREGRFGQSCQEQCP 273 Query: 312 H---CRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTG 368 CR C PD C C GW G +C++ C G FG DC C G+CD +G Sbjct: 274 GISGCRGLTFCLPDPYGCS-CGSGWRGSQCQEACAPGHFGADCRLQCQCQNGGTCDRFSG 332 Query: 369 DCVCSAGYWGPSCNAS 384 CVC +G+ G C S Sbjct: 333 -CVCPSGWHGVHCEKS 347 Score = 89.4 bits (220), Expect = 1e-17 Identities = 44/125 (35%), Positives = 56/125 (44%), Gaps = 10/125 (8%) Query: 297 CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCP 356 C G +G C ++CP C HG C G C C PG+ G RCE C G FG+ C CP Sbjct: 215 CGAGRWGPGCTKECPGCLHGGVCHDHDGECV-CPPGFTGTRCEQACREGRFGQSCQEQCP 273 Query: 357 TCVQGSCDTVTG------DCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE-GLCHPVS 409 C +T C C +G+ G C +C G G +C + C+C G C S Sbjct: 274 GI--SGCRGLTFCLPDPYGCSCGSGWRGSQCQEACAPGHFGADCRLQCQCQNGGTCDRFS 331 Query: 410 GSCQP 414 G P Sbjct: 332 GCVCP 336 Score = 82.0 bits (201), Expect = 2e-15 Identities = 47/139 (33%), Positives = 61/139 (43%), Gaps = 17/139 (12%) Query: 120 CQADRWGARCEFPC-ACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ---- 174 C A RWG C C C G C G C C PG+ + C + C+ C++ Sbjct: 215 CGAGRWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPG 274 Query: 175 ---ATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG-RC 230 G C P +G CS GS C++ AC PG +G +C+ QC+C G C Sbjct: 275 ISGCRGLTFCLPDPYG--CSCGSGWRGSQCQE-----ACAPGHFGADCRLQCQCQNGGTC 327 Query: 231 SAASGECTCPPGFRGARCE 249 SG C CP G+ G CE Sbjct: 328 DRFSG-CVCPSGWHGVHCE 345 Score = 75.9 bits (185), Expect = 1e-13 Identities = 43/138 (31%), Positives = 60/138 (43%), Gaps = 12/138 (8%) Query: 90 CPGQYWGPDCRESCP-CHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRC--DPATG 146 C WGP C + CP C G C G C C G RCE C G G+ + G Sbjct: 215 CGAGRWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPG 274 Query: 147 VCHCEPGWWSSTCRRPCQCNTA--AARCEQATGACVCKPGWWGRRCSFRCNC-HGSPCEQ 203 + C + C C + ++C++A C PG +G C +C C +G C++ Sbjct: 275 ISGCRGLTFCLPDPYGCSCGSGWRGSQCQEA-----CAPGHFGADCRLQCQCQNGGTCDR 329 Query: 204 DSGRCACRPGWWGPECQQ 221 SG C C GW G C++ Sbjct: 330 FSG-CVCPSGWHGVHCEK 346 Score = 72.0 bits (175), Expect = 2e-12 Identities = 42/143 (29%), Positives = 57/143 (39%), Gaps = 30/143 (20%) Query: 59 GPDACQKDEVCVKPGLCR-------CKPGFFGAHCSSRCPGQYWGPDCRESCP----CHP 107 GP ++ C+ G+C C PGF G C C +G C+E CP C Sbjct: 221 GPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGISGCRG 280 Query: 108 HGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNT 167 C P C C + G++C+ CA PG + + CR CQC Sbjct: 281 LTFCLPDPYGCSCGSGWRGSQCQEACA-----------------PGHFGADCRLQCQCQN 323 Query: 168 AAARCEQATGACVCKPGWWGRRC 190 C++ +G CVC GW G C Sbjct: 324 GGT-CDRFSG-CVCPSGWHGVHC 344 Score = 56.6 bits (135), Expect = 9e-08 Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 6/84 (7%) Query: 342 CPTGTFGEDCGSTCPTCVQGS-CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC 400 C G +G C CP C+ G C G+CVC G+ G C +C G G +C C Sbjct: 215 CGAGRWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPG 274 Query: 401 PEG-----LCHPVSGSCQPGSGSR 419 G C P C GSG R Sbjct: 275 ISGCRGLTFCLPDPYGCSCGSGWR 298 Score = 51.6 bits (122), Expect = 3e-06 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Query: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPAT 115 C G C+ C+ P C C G+ G+ C C ++G DCR C C G C+ + Sbjct: 272 CPGISGCRGLTFCLPDPYGCSCGSGWRGSQCQEACAPGHFGADCRLQCQCQNGGTCDRFS 331 Query: 116 GACQCQADRWGARCE 130 G C C + G CE Sbjct: 332 G-CVCPSGWHGVHCE 345 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.467 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,321,477 Number of Sequences: 37866 Number of extensions: 2870066 Number of successful extensions: 24614 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 188 Number of HSP's successfully gapped in prelim test: 992 Number of HSP's that attempted gapping in prelim test: 12659 Number of HSP's gapped (non-prelim): 5275 length of query: 830 length of database: 18,247,518 effective HSP length: 111 effective length of query: 719 effective length of database: 14,044,392 effective search space: 10097917848 effective search space used: 10097917848 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.