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Search of human proteins with 33286436
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33286436 gametogenetin [Homo sapiens]
(652 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33286436 gametogenetin [Homo sapiens] 1358 0.0
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 114 2e-25
gi|160707881 formin 2 [Homo sapiens] 114 4e-25
gi|163965366 nascent polypeptide-associated complex alpha subuni... 111 2e-24
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 102 1e-21
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 100 7e-21
gi|18079216 CASK interacting protein 1 [Homo sapiens] 98 2e-20
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 98 3e-20
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 93 7e-19
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 88 2e-17
gi|47132519 Ras association and pleckstrin homology domains 1 is... 87 6e-17
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 85 2e-16
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 84 4e-16
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 84 4e-16
gi|110832843 TBP-associated factor 4 [Homo sapiens] 84 4e-16
gi|153792074 proline rich 12 [Homo sapiens] 84 5e-16
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 83 9e-16
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 82 1e-15
gi|112421108 capicua homolog [Homo sapiens] 82 1e-15
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 82 2e-15
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 81 3e-15
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 81 3e-15
gi|18959210 WIRE protein [Homo sapiens] 81 3e-15
gi|55750053 atrophin-1 [Homo sapiens] 80 5e-15
gi|55750041 atrophin-1 [Homo sapiens] 80 5e-15
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 79 1e-14
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 78 2e-14
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 78 3e-14
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 78 3e-14
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 78 3e-14
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 1358 bits (3514), Expect = 0.0
Identities = 652/652 (100%), Positives = 652/652 (100%)
Query: 1 MGNLQSEPSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGL 60
MGNLQSEPSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGL
Sbjct: 1 MGNLQSEPSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGL 60
Query: 61 MVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVP 120
MVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVP
Sbjct: 61 MVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVP 120
Query: 121 RIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSE 180
RIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSE
Sbjct: 121 RIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSE 180
Query: 181 RQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLS 240
RQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLS
Sbjct: 181 RQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLS 240
Query: 241 LLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAAR 300
LLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAAR
Sbjct: 241 LLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAAR 300
Query: 301 PLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGP 360
PLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGP
Sbjct: 301 PLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGP 360
Query: 361 ERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPA 420
ERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPA
Sbjct: 361 ERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPA 420
Query: 421 PTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTA 480
PTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTA
Sbjct: 421 PTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTA 480
Query: 481 APALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRK 540
APALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRK
Sbjct: 481 APALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRK 540
Query: 541 DGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAARHWLPFQVLNSCPCKCYCHH 600
DGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAARHWLPFQVLNSCPCKCYCHH
Sbjct: 541 DGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAARHWLPFQVLNSCPCKCYCHH 600
Query: 601 QPRHRRLPRNVSAWLSTSTNHLGEPPWVATIKLSGSLVAKLEHYDLQATHSN 652
QPRHRRLPRNVSAWLSTSTNHLGEPPWVATIKLSGSLVAKLEHYDLQATHSN
Sbjct: 601 QPRHRRLPRNVSAWLSTSTNHLGEPPWVATIKLSGSLVAKLEHYDLQATHSN 652
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 114 bits (286), Expect = 2e-25
Identities = 156/601 (25%), Positives = 216/601 (35%), Gaps = 126/601 (20%)
Query: 8 PSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQ 67
PSAGGG ++ P+ R+ S T L P + + R T P P GL R PQ
Sbjct: 228 PSAGGGLQR--PASRSLSSSATPLSSPARSGPSARGTPRAPA-HPSQPKPKGLQALRPPQ 284
Query: 68 -------ASPSTLPLTLERPSPVMPP-PEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPV 119
A+P+ PL+ SP+ P P A PPP A T LP P TP+
Sbjct: 285 VTPPRKDAAPALGPLS---SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341
Query: 120 PRIRRLLEASHRGQGDPPSLRPLKPPP--PPRQLSVKDTVPRAPSQFPPPLET------- 170
P + PPSL+ L PP PP Q T P P Q PP L+T
Sbjct: 342 P-------LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP--PMQAPPSLQTIPPIQVP 392
Query: 171 --------WKPPPPL---------------------------------------PSERQP 183
PP PL P+ P
Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452
Query: 184 ADRRITPALATPASPPTESQAGPRNQGQTAG------RARGGAPPHAGEGEMAQ----PA 233
+ L+ PASPP ++ P ++ +A H+ + ++ P
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512
Query: 234 DSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGP 293
+++S L+ PSL P AS + +L L AS ++ L+ P
Sbjct: 513 ETQSSLA---------PPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH-LETPP 562
Query: 294 LPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQA----RALPPPPYTTFPGSKP 349
P A PL + + + PP AP + A + LP PP + P
Sbjct: 563 CP--APCPL-QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619
Query: 350 K------FDWVSAPDGPERHFRFNG-AGGGIGAPRRRAA-ALSGPWGSPPPPPEQIHSAP 401
+ + AP P + A AP A L P+ PP PP Q +P
Sbjct: 620 QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 679
Query: 402 GPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPP-TPPPTLQPP-ALQPTPL 459
P PP+ P+ P PP PP+ P TPPP PP A P +
Sbjct: 680 PASPPVSPSATPPSQA--PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQV 737
Query: 460 PVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAA 519
P +PP +P + + + T P +PP LAA P P+P + P P++ P P A
Sbjct: 738 PPSPPASPPM-----SPSATPPPRVPPLLAAPPLQVP---PSPPASLPMSPLAKPPPQAP 789
Query: 520 P 520
P
Sbjct: 790 P 790
Score = 104 bits (259), Expect = 3e-22
Identities = 150/596 (25%), Positives = 195/596 (32%), Gaps = 116/596 (19%)
Query: 1 MGNLQSEPSAGGGSRKVQPS--DRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPP 58
+ +LQ+ S G + + S +P + SL P + + L A+PP
Sbjct: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468
Query: 59 GLMVPREPQASPSTLPLTLER----PSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKP 114
L P SP + PLT+ S P+ + PP + L PS P
Sbjct: 469 -LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527
Query: 115 AGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPP-PLETWKP 173
A P + L + PP L+ P L P Q PP PL T P
Sbjct: 528 ASLTTPPLENLPSLA------PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT--P 579
Query: 174 PPPLPSERQPADRRITPALATPA-----SPPTESQAGPRNQGQTAGRARGGAPPHAGEGE 228
PP PS + PALA+P SPP A P Q APP
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ----------APPXLALPP 629
Query: 229 MAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEV 288
+ P + P L+P A S A A A
Sbjct: 630 LQAPPSPPAS------------PPLSPLATPSPQAPNA------------------LAVH 659
Query: 289 LKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSK 348
L Q P P + P+ + PP +P++ + PP P
Sbjct: 660 LLQAPFSPPPSPPV-------------QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 706
Query: 349 PKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAP 408
P S P P + P A L P P PP + P PR P P
Sbjct: 707 PPSPPASPPMSP------SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP-P 759
Query: 409 ALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVA-----P 463
L APP + P+P PM P PPP PP L P LQ P P A
Sbjct: 760 LLAAPPLQVPPSPPASLPMSP--------LAKPPPQAPPALATPPLQALPSPPASFPGQA 811
Query: 464 PLTPGLGHKESALA---PTAAPAL----------PPALAADQAPAPSPAPAPTVAEPSP- 509
P +P S LA P A P L PPA QAP P P P + P
Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 871
Query: 510 ------PVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHG--DGPRERATATVP 557
P P P+ +P T + + ++ + + L G GP A A+ P
Sbjct: 872 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 927
Score = 90.5 bits (223), Expect = 4e-18
Identities = 132/546 (24%), Positives = 173/546 (31%), Gaps = 94/546 (17%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW 111
P PP L P Q PS L P P PP + APP PA L
Sbjct: 590 PPPQAPPALASP-PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL------ 642
Query: 112 QKPAGTPVPRIRR-----LLEASHRGQGDPPSLRPLKPPP-PPRQLSVKDTVPRAPSQFP 165
P TP P+ LL+A PP P PP PP S PS
Sbjct: 643 -SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 701
Query: 166 PPLETWKPPP---PLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPP 222
PPL+ PP P+ P + P A P P A P R PP
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR--VPP 759
Query: 223 HAGEGEMAQPADSESGLSL--LCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAAS 280
+ P + L + L K ++ P+LA P + + AS G F+ S
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP---FSPS 816
Query: 281 GAISYAEVLKQGP-LPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPP 339
++ + + P PP A PL +V PP++P QA PP
Sbjct: 817 ASLPMSPLATPPPQAPPVLAAPLLQVP----------------PSPPASPTLQAPRRPPT 860
Query: 340 PYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHS 399
P GP+ + PR A GP PPPP +
Sbjct: 861 P------------------GPDT---------SVSGPRLTLALAPGP----PPPPSR--- 886
Query: 400 APGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPT------------PPP 447
+P P L + P GP G P P P P
Sbjct: 887 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 946
Query: 448 TLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEP 507
L PLP P PG + T P A A A P P+P + +
Sbjct: 947 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP--ESATPAPGALDPGPSPGTSGGKA 1004
Query: 508 SPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGS 567
+ A A + +P + R GA + + R A ++GG GGG
Sbjct: 1005 AAGAGAGASSRSPKQARL-----GELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGP 1059
Query: 568 GASQTG 573
G ++ G
Sbjct: 1060 GGAEGG 1065
Score = 87.8 bits (216), Expect = 3e-17
Identities = 148/539 (27%), Positives = 194/539 (35%), Gaps = 94/539 (17%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW 111
PG+ +P + R +A+ + + L PS PP E S + T P P+
Sbjct: 169 PGTPSPA---MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 225
Query: 112 QKPA---GTPVPRIRRLLEA---------------------SHRGQGDPPSLRPLKPP-- 145
++P+ G P R L + +H Q P L+ L+PP
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 146 PPPRQLSVKDTVP------RAPSQFPPPLETWK---PPPPLPSERQPADRRITPALAT-- 194
PPR KD P +P P P T PPP + PA +P LAT
Sbjct: 286 TPPR----KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341
Query: 195 PASPPTESQAGPRNQGQTAGRAR--GGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPS 252
P +PP+ S A P Q + A APP M P ++ + + S
Sbjct: 342 PLAPPSPS-APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL 400
Query: 253 LAPPA--ASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQ 310
APP+ A SSL A SL G L A ++ + P L SR A
Sbjct: 401 QAPPSPLALSSLQATTSL---GSPTLQATHSFLTMS--------PRQTQASLTSPSRPAS 449
Query: 311 EAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAG 370
D P S PAS P + S + A H
Sbjct: 450 TPP----DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505
Query: 371 GGIGAPRRRAAALSGP-WGSPP-----PPPEQIHS-APGPRRPAPALLAPPTFIFPAPTN 423
I P ++L+ P +PP PP E + S AP P + A A L P P
Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565
Query: 424 GEPMRPGPPGLQELPP-------LPPPTPPPTLQPPALQPTPLPVAPPLT--PGLGHKES 474
P++ P L PP PPP PP L P LQ P P PL P
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625
Query: 475 ALAPTAAPALPPALAADQAPAPSPAP------------APTVAEPSPPVSAP-APAAAP 520
AL P AP PPA + +P +P+P AP PSPPV AP +P A+P
Sbjct: 626 ALPPLQAPPSPPA-SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Score = 73.9 bits (180), Expect = 4e-13
Identities = 134/525 (25%), Positives = 177/525 (33%), Gaps = 126/525 (24%)
Query: 54 SATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQK 113
+A PGL+ PR P SP PPP AA+ A A P +
Sbjct: 18 AARAPGLLTPRPP-------------GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64
Query: 114 PAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPP----PRQLSVKDTVPRAPSQFPPPLE 169
G +P A S P PP R K+T P P P
Sbjct: 65 IGGATIP--ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP-GPVSSPGRAS 121
Query: 170 TWKPPPPLPSE--RQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEG 227
P PL + R A+ + AT A + AG R T+G G P
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR--DTSGPTPG--TPSPAMA 177
Query: 228 EMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASL----------GGGGGGGLF 277
++ A +E GL + + RP P S S A++ S GGG
Sbjct: 178 RRSRAAGTEVGLPRPAP-SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
Query: 278 AASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALP 337
AS ++S +A PL +R G G P APA
Sbjct: 237 PASRSLS------------SSATPLSSPAR----------SGPSARGTPRAPAHP----- 269
Query: 338 PPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPP---PPP 394
S+PK + A P+ + PR+ AA GP S P P P
Sbjct: 270 ---------SQPKPKGLQALRPPQ-----------VTPPRKDAAPALGPLSSSPLATPSP 309
Query: 395 EQIHSAPGP-----RRPAPALLAP-PTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPT 448
+ P P P PA L P P P P P PP LQ LP PP PP+
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPL-APPSPSAPPSLQTLP--SPPATPPS 366
Query: 449 LQPPALQPTPLPVAPPL--TPGLGHKESALAPT-AAPALPPALAA--------------- 490
PP++ P+ P L P + S +P+ AP P AL++
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
Query: 491 ----------DQAPAPSPAPAPTVAEPSPPVSAP--APAAAPIKT 523
QA SP+ + SPP+ AP PA+ P++T
Sbjct: 427 HSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT 471
Score = 45.4 bits (106), Expect = 2e-04
Identities = 64/251 (25%), Positives = 81/251 (32%), Gaps = 29/251 (11%)
Query: 325 PPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGI-------GAPR 377
PP +P PPPP T P + A R G GG P
Sbjct: 29 PPGSPR------PPPPVT--PAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80
Query: 378 RRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQEL 437
R A S S PP S G R P +P P +G RPGP G + L
Sbjct: 81 RSAGTSSRNPASRPPA-----SGRGERAPPAKNTSPGPVSSPGRASGTT-RPGPLGQKGL 134
Query: 438 PPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAP-TAAPALPPALAADQAPAP 496
T + T P L+ G S P T +PA+ A
Sbjct: 135 RISAEETVARG------KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 497 SPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATV 556
P PAP+ A P PP P + + + A R + GL R +++
Sbjct: 189 LPRPAPS-ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 557 PDSSGGGGGGS 567
P SS G S
Sbjct: 248 PLSSPARSGPS 258
Score = 43.1 bits (100), Expect = 8e-04
Identities = 49/164 (29%), Positives = 62/164 (37%), Gaps = 17/164 (10%)
Query: 432 PGLQELPPLPP--PTPPPTLQPPALQPTPLPVA---PPLTPGLGHKESALAPTAAPALPP 486
PGL L P PP P PPP + P AL+ A PL G A P +AP P
Sbjct: 22 PGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGP 79
Query: 487 ALAADQA---PAPSPAP------APTVAEPSP-PVSAPAPAAAPIKTRTRRNKGSRAARG 536
+A + PA P AP SP PVS+P A+ + KG R +
Sbjct: 80 TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
Query: 537 ATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAA 580
T G + P+ A + G S A +RAA
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 114 bits (284), Expect = 4e-25
Identities = 137/472 (29%), Positives = 158/472 (33%), Gaps = 88/472 (18%)
Query: 46 GLGVWFPGSATPPGLMVPREPQ-ASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTL 104
GLG+ P PG+ VP P A P PL P PPP A + PPP P +
Sbjct: 872 GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI 931
Query: 105 LPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQF 164
LP P AG P P PP PPPPP +P A
Sbjct: 932 LPLPPL--PGAGIPPP---------------PPLPGAAIPPPPP--------LPGAGIPL 966
Query: 165 PPPLETW--KPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPP 222
PPPL PPPPLP P + P P PP AG G PP
Sbjct: 967 PPPLPGAGIPPPPPLPGAGIPPPPPL-PGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPP 1024
Query: 223 HAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGA 282
G G P +G+ + P PP + + L G G
Sbjct: 1025 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAG---------- 1073
Query: 283 ISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYT 342
+ P PGA P GA G G PP P + +PPPP
Sbjct: 1074 ------IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA---GIPPPPPL 1124
Query: 343 TFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPG 402
G P P P G GI P G PPPPP P
Sbjct: 1125 PGAGIPPP------PPLP---------GAGIPPPPPLPRV-----GIPPPPPLPGAGIPP 1164
Query: 403 PRRPAPALLAPPTFIFPAPTNGEPMRPGPP----GLQELPPLPPP--TPPPTLQPPALQP 456
P P P PP P P G + P PP G+ PPLP PPP L + P
Sbjct: 1165 PP-PLPGAGIPP----PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPP 1219
Query: 457 TPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPS-----PAPAPT 503
P P PP PG G L P + P L P + + P P P P P+
Sbjct: 1220 APAPPLPP--PGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPS 1269
Score = 99.4 bits (246), Expect = 9e-21
Identities = 146/534 (27%), Positives = 170/534 (31%), Gaps = 133/534 (24%)
Query: 9 SAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFP-------GSATPPGL- 60
SAG G QP + P S T S + + P S++ PGL
Sbjct: 819 SAGQG----QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLG 874
Query: 61 MVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVP 120
MVP P P TL + PPP + + PPP P LPG P P+P
Sbjct: 875 MVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP----LPGAGI---PPPPPLP 927
Query: 121 RIRRLLEASHRGQGDPPSLRPLK----PPPPPRQLSVKDTVPRAPSQFPPPLETW--KPP 174
L G G PP PL PPPPP +P A PPPL PP
Sbjct: 928 GAGILPLPPLPGAGIPPP-PPLPGAAIPPPPP--------LPGAGIPLPPPLPGAGIPPP 978
Query: 175 PPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPAD 234
PPLP P + P P PP P PP G G P
Sbjct: 979 PPLPGAGIPPPPPL-PGAGIPPPPPLPGAGIPP------------PPPLPGAGIPPPPPL 1025
Query: 235 SESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPL 294
+G+ PP + + L G G +
Sbjct: 1026 PGAGIPP------------PPPLPGAGIPPPPPLPGAG---------------------I 1052
Query: 295 PPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWV 354
PP P G G PP P + +PPPP G P
Sbjct: 1053 PPPPPLP-----------------GAGIPPPPPLPGA---GIPPPPPLPGAGIPPP---- 1088
Query: 355 SAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPP 414
P P G GI P L G G PPPPP P P P P PP
Sbjct: 1089 --PPLP---------GAGIPPP----PPLPGV-GIPPPPPLPGAGIPPPP-PLPGAGIPP 1131
Query: 415 TFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQP-TPLPVAPPLTPGLGHKE 473
P P G + P PP + P PPP P + PP P +P PPL PG+G
Sbjct: 1132 ----PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-PGVGIPP 1186
Query: 474 SALAPTAAPALPPALAADQAPAPSP------APAPTVAEPSPPVSAPAPAAAPI 521
P PP L P P P PAP P P P P P+
Sbjct: 1187 PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPV 1240
Score = 63.9 bits (154), Expect = 4e-10
Identities = 62/211 (29%), Positives = 75/211 (35%), Gaps = 42/211 (19%)
Query: 331 SQARALPPPPYTTF-------PGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAAL 383
+Q+ + PPPP + PGS+P + H + P
Sbjct: 804 TQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIP------- 856
Query: 384 SGPWGSPPPPP--EQIHSAPG------PRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQ 435
SPPP P E S PG P P P + P P+ P P G +
Sbjct: 857 -----SPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTL-----PSTAIPQPPPLQGTE 906
Query: 436 ELPPLPPPTPPPTLQPPALQPTPLPVA-----PPLTPGLGHKESALAPTAAPALPPALAA 490
LPP PPP P + P P PLP A PPL PG G P AA PP L
Sbjct: 907 MLPPPPPPLPGAGIPP----PPPLPGAGILPLPPL-PGAGIPPPPPLPGAAIPPPPPLPG 961
Query: 491 DQAPAPSPAPAPTVAEPSPPVSAPAPAAAPI 521
P P P P + P P A P P+
Sbjct: 962 AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPL 992
Score = 36.6 bits (83), Expect = 0.075
Identities = 49/217 (22%), Positives = 73/217 (33%), Gaps = 39/217 (17%)
Query: 390 PPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPP-------GLQELPPLPP 442
P PP + PG A L F+ P+ G PG P L +LP
Sbjct: 232 PAAPPTAVSPQPG------AFLGLDRFLL-GPSGGAGEAPGSPDTEQALSALSDLPESLA 284
Query: 443 PTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPAL-AADQAPAPSPAPA 501
P QPP+ P LPV + AP+LP A AA +P+ + P
Sbjct: 285 AEPREPQQPPS--PGGLPV-----------------SEAPSLPAAQPAAKDSPSSTAFPF 325
Query: 502 PTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKD---GLHGDGPRERATATVPD 558
P AP A + A RG+ ++ + D P+ P+
Sbjct: 326 PEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQR--LGEEPE 383
Query: 559 SSGGGGGGSGASQTGAANTRAARHWLPFQVLNSCPCK 595
G A+ + + R + P+ ++ C K
Sbjct: 384 EEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIK 420
Score = 35.8 bits (81), Expect = 0.13
Identities = 84/336 (25%), Positives = 112/336 (33%), Gaps = 47/336 (13%)
Query: 251 PSLAPPAASSSLAAKASLGG---GGGGGLFAASGAISYAEVLKQ-GPLPPGAARPLGEVS 306
P+ P A S A L G GG A G+ + L LP A E
Sbjct: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLA---AEPR 288
Query: 307 RGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRF 366
Q G G S PS PA+Q A P T FP + A G E
Sbjct: 289 EPQQPPSPG---GLPVSEAPSLPAAQPAAKDSPSSTAFP-------FPEAGPGEEAAGAP 338
Query: 367 NGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEP 426
G A P GSP AP AP L E
Sbjct: 339 VRGAGDTDEEGEEDAFEDAPRGSPGE-----EWAPEVGEDAPQRLG-------EEPEEEA 386
Query: 427 MRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPP 486
P P LP P P+ +P PL +TP + ++ ++P P
Sbjct: 387 QGPDAPAAASLPGSPAPS------QRCFKPYPL-----ITP--CYIKTTTRQLSSPNHSP 433
Query: 487 ALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRA--ARGATRKDGLH 544
+ + +Q+P P P+++ S +A A AAP K + R + G A +R A + L
Sbjct: 434 SQSPNQSPRIKRRPEPSLSRGSR--TALASVAAPAK-KHRADGGLAAGLSRSADWTEELG 490
Query: 545 GDGPRERATATVPDSSGGGGGGSGASQTGAANTRAA 580
PR +A + + G G S AA A
Sbjct: 491 ARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGA 526
Score = 30.4 bits (67), Expect = 5.3
Identities = 28/87 (32%), Positives = 34/87 (39%), Gaps = 13/87 (14%)
Query: 66 PQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPA----GTLLPGPSK---WQKPAGTP 118
P SP+ P RP P + A S PA G L G S+ W + G
Sbjct: 433 PSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGAR 492
Query: 119 VPRI---RRLLE---ASHRGQGDPPSL 139
PR+ LLE AS G G P+L
Sbjct: 493 TPRVGGSAHLLERGVASDSGGGVSPAL 519
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 111 bits (277), Expect = 2e-24
Identities = 139/556 (25%), Positives = 196/556 (35%), Gaps = 99/556 (17%)
Query: 56 TPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPA 115
+P G+ +P + +PS + L + P P P++A A+S +P +K
Sbjct: 874 SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP-----------KKAR 922
Query: 116 GTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPP-PLETWKPP 174
TP P+ G P S P P PP P +P P P W P
Sbjct: 923 ATPAPK------------GIPASPSPKGAPTPPA------ATPPSPKGGPATPSPKWAPT 964
Query: 175 PPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPAD 234
PP + P TP+ +PP + P+ T PP + P+
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP-----AVTPPSP 1019
Query: 235 SESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGG---GGGLFAASGAISYAEVLKQ 291
S + + P+ PP+ S AA G L + G + LK
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPS-LKG 1078
Query: 292 GPLPPGAARPLGEVSRGAQEAEGGDG--DGEGCSGPPSA-PASQARALPPPPYTTFPGSK 348
P PP A P +GG +G PP+A P S L PP+ P +
Sbjct: 1079 APTPPAATPP---------SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129
Query: 349 PKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPP--------PPPEQIHSA 400
+ P P+ GG+ P + A + P +PP PPP+ +
Sbjct: 1130 -----AATPPSPK---------GGLATPPPKGAPTT-PAATPPSPKGGLATPPPKGAPTT 1174
Query: 401 PGPRRPAP--ALLAP--------PTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQ 450
P P+P L P P P+P G P P G P PP+P L
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT-PSPKGAPTTPAATPPSPKGGLA 1233
Query: 451 PPALQPTPL-PVAPPLTP--GLGHKESALAPTAAPALPPALAADQAPAPSP-APAPTVAE 506
P+ + P P A P +P G APT A PP+L A P AP P V
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293
Query: 507 P---------SPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVP 557
P SPP AP P AA + + + G+ +GA + P+ T
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPS-PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPAT 1352
Query: 558 DSSGGGGGGSGASQTG 573
S GG + +S+ G
Sbjct: 1353 TPSSKGGPTTPSSKEG 1368
Score = 103 bits (258), Expect = 4e-22
Identities = 147/544 (27%), Positives = 194/544 (35%), Gaps = 75/544 (13%)
Query: 53 GSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQ 112
G+ TPP + P P+ SP+ P P PP AA +P +PA T LP +
Sbjct: 1007 GAPTPPAV-TPPSPKGSPAATPF----PKGASTPP--AATPPSPKGSPAATPLPKGAPTT 1059
Query: 113 KPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPP-PLETW 171
A P P+ S +G PP+ P P P S K P P+ PP P
Sbjct: 1060 PAATLPSPK-GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA-PMPPAATPPSPKGGL 1117
Query: 172 KPPPPLPSERQPADRRITP--ALATP---ASPPTESQAGPRNQGQTAGRARGGAPPHAGE 226
PP + PA +P LATP +P T + P +G A GAP
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA- 1176
Query: 227 GEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYA 286
A P + GL+ + P+ PP+ LA + G S A
Sbjct: 1177 ---ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233
Query: 287 EVLKQG-PLPPGAARPLGEVSRGAQEAEGGDGDG--EGCSGPPSA-PASQARALPPPPYT 342
+G P P A P +GG +G PP+A P S L PP+
Sbjct: 1234 TPSPKGAPTTPAATPP---------SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Query: 343 TFPGSKPKFDWVSAPDGPERHFRFNGAGGGI-----GAPRRRAAALSGPWGSP-PPPPEQ 396
P V P P+ GG GAP AA P GSP PPP+
Sbjct: 1285 GAPNPA-----VVTPPSPK--------GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG 1331
Query: 397 IHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPP----PTLQPP 452
+ P P+P PT PA T P P +E P P TP P + PP
Sbjct: 1332 APTPPAVTPPSPK--GTPTL--PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387
Query: 453 ALQ---PTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPS----PAPAPTVA 505
+ + P P P +P + L+P APA P P+ PA P
Sbjct: 1388 SPKRGPAIPSPKGDPTSPAV----IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443
Query: 506 EPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGG 565
+ +P SAP A T +KG T P++ AT++ P +
Sbjct: 1444 KKAPATSAPKGGPA-----TPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA 1498
Query: 566 GSGA 569
GA
Sbjct: 1499 PMGA 1502
Score = 101 bits (251), Expect = 2e-21
Identities = 144/568 (25%), Positives = 189/568 (33%), Gaps = 85/568 (14%)
Query: 53 GSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTL-LPGP-SK 110
G ATPP P P A+P + L PSP P AA PP+P G L P P
Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT----PPSPKGGLATPSPKGA 1217
Query: 111 WQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKP-----PPPPRQLSVKDTVPRAPSQFP 165
PA TP L S +G P+ P P PPP+ P P+ P
Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK------GAPTPPAATP 1271
Query: 166 PPLETWKPPP-----PLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGR--ARG 218
P L+ P P P+ P + PA + P PT A P + + G +G
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG 1331
Query: 219 GAPPHA------------------GEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASS 260
P A +G P+ E + K P++ PP+
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR 1391
Query: 261 SLAAKASLGGGGGGGLFAASGAISYAEVL--------KQGPLPPGAARPLGEVSRGAQEA 312
A + G + S + A + +G L P A P+ A A
Sbjct: 1392 GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA 1451
Query: 313 EGGDGDGEGCSGPPSAPA--SQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAG 370
G G P+ PA + PP P S PK AP P
Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK----KAPATP---------- 1497
Query: 371 GGIGAPRRRAAALSGPWGSPPPPPEQ---------IHSAPGPRRPAP-ALLAPPTFIFPA 420
+GAP A S P P P + + S P AP L PP P+
Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 421 PTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLP---VAPPLTPGLGHKESALA 477
P P P P P + PP + P + P P + PP KE+
Sbjct: 1558 PKK-TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616
Query: 478 PTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIK---TRTRRNKGSRAA 534
P P P A AP +P +P V S S +PA+ K T + +KG A
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPT-SPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675
Query: 535 RGATR-KDGLHGDGPRERATATVPDSSG 561
+G T K+ L P T P G
Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKG 1703
Score = 100 bits (248), Expect = 5e-21
Identities = 141/547 (25%), Positives = 189/547 (34%), Gaps = 92/547 (16%)
Query: 53 GSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW- 111
G+ TPP P P+ P+T PSP P AA PP+P G L P K
Sbjct: 1078 GAPTPPA-ATPPSPKGGPAT-------PSPKGAPMPPAAT----PPSPKGGLATPPHKGA 1125
Query: 112 -QKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKP-----PPPPRQLSVKDTVPRAPSQFP 165
PA TP L +G P+ P P PPP+ P P+ P
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK------GAPTTPAATP 1179
Query: 166 P-PLETWKPPPPLPSERQPADRRITP--ALATPA---SPPTESQAGPRNQGQTAGRARGG 219
P P P P + PA +P LATP+ +P T + P +G A + G
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239
Query: 220 APPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAA 279
AP A P + G + + P+ PP+ LA G +
Sbjct: 1240 APTTPA----ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295
Query: 280 SGAISYAEVLKQG-PLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPP 338
S A +G P PP A P + + G +G PP+ + P
Sbjct: 1296 SPKGGPATSPPKGAPTPPAATPP-------SPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348
Query: 339 PPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGG---IGAPRRRAAALSGPWGSPPPP-- 393
P TT P SK S+ +GP GG +R A+ P G P P
Sbjct: 1349 LPATT-PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407
Query: 394 ----PEQIHSAP----GPRRPAPALLAPPTF----IFPAPTNGEPM-RPGPPGLQELPPL 440
P++ + P G P+ L PP + AP P P P + P L
Sbjct: 1408 IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 441 PPPTPPPTLQPPA------------LQPTPLPVAPPLTPGL------------GHKESAL 476
P TPP +PPA TP P+ P P + + +
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 477 APTA---APALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRA 533
APTA + P LA +A P PA TV P + P P AP ++ A
Sbjct: 1528 APTATLLSKKTPATLAPKEALIP---PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584
Query: 534 ARGATRK 540
+T K
Sbjct: 1585 VTPSTYK 1591
Score = 96.7 bits (239), Expect = 6e-20
Identities = 138/531 (25%), Positives = 182/531 (34%), Gaps = 96/531 (18%)
Query: 69 SPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLL-- 126
SPS L +++ P PP ++ SA P P G L +PV +
Sbjct: 793 SPSPLGVSVS-PQTKRPPTKKG---SAGPDTPIGNL-----------SSPVSPVEASFLP 837
Query: 127 --EASHRGQGDPPSLRPLKPPPPPRQLSVKDTV-PRAPSQFP-PPLETWKP-----PPPL 177
S +G D P+ PP P+ V P +P PP ET P P P
Sbjct: 838 ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK 897
Query: 178 PSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSES 237
PA ++ PAL+ +S P +++A P +G A + GAP A P +
Sbjct: 898 EGPATPAPKQ-APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA----ATPPSPKG 952
Query: 238 GLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPG 297
G + + P+ PP+ A + G P PP
Sbjct: 953 GPATPSPKWAPTPPAATPPSPKGGPATPSPKGA----------------------PTPPA 990
Query: 298 AARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAP 357
A P + +G PPS S A P +T P + P S
Sbjct: 991 ATPPSPKGGPATPSPKGAPTPP--AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 358 DGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFI 417
P GAP AA L P G P P + AP P P
Sbjct: 1049 ATPLPK----------GAPTTPAATLPSPKGGPATP--SLKGAPTPPAATP--------- 1087
Query: 418 FPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPL-PVAPPLTP--GLGHKES 474
P+P G P P P G P PP+P L P + P P A P +P GL
Sbjct: 1088 -PSPKGG-PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP 1145
Query: 475 ALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPP-----VSAPAPAAAPIKTRTRRNK 529
APT A PP+ A P P APT +PP ++ P+P AP
Sbjct: 1146 KGAPTTPAATPPSPKGGLA-TPPPKGAPTTPAATPPSPKGGLATPSPKGAPT-------- 1196
Query: 530 GSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAA 580
+ AA + K GL P+ T GG + S GA T AA
Sbjct: 1197 -TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246
Score = 84.0 bits (206), Expect = 4e-16
Identities = 144/595 (24%), Positives = 196/595 (32%), Gaps = 61/595 (10%)
Query: 16 KVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSA--TPPGL-----MVPREPQA 68
K PS ++ S + PE T L L + P S+ +P G+ ++ + A
Sbjct: 568 KNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA 627
Query: 69 SPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEA 128
P + L + S + P SA P A T G S + A + L
Sbjct: 628 GPDSAGPLL-KSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPK 686
Query: 129 SHRGQGDPPSLRPLKPPPP---PRQLSVKDT-VPRAPSQFPPPLETWKPPPPLP-SERQP 183
+H + + PL P P S ++T P A P + P P LP + P
Sbjct: 687 NHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPP 746
Query: 184 ADRRI-----TPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESG 238
+++ T ALA AS P E TA + +G + ADS S
Sbjct: 747 GTKKVDGISHTSALAPVASSPKECPTEDSGASATA----------SSKGTLTYLADSPSP 796
Query: 239 LSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISY-----AEVLKQGP 293
L + K P+ A + S F ++S+ + P
Sbjct: 797 LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSP 856
Query: 294 LPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPS-APASQARALPPP---PYTTFPGSKP 349
PP P G + A +G + PP P LP P P T P P
Sbjct: 857 TPPS---PKGAPTPSAVTPLSP----KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909
Query: 350 KFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPA 409
S+ + R A GI A A + P +PP P GP P+P
Sbjct: 910 ALSMTSSSP---KKARATPAPKGIPASPSPKGAPTPPAATPPSPKG------GPATPSPK 960
Query: 410 LLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPP--PTLQPPALQPTPLPVAPPLTP 467
P P G P P P G P PP+P P P PTP V PP
Sbjct: 961 WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020
Query: 468 GLGHKESALAPTAAPALPPALAADQAPAPSPA--PAPTVAEPSPPVSAPAPAAAPIKTRT 525
G A P A P A +P SPA P P A +P + P+P P
Sbjct: 1021 G----SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076
Query: 526 RRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAA 580
+ AA + K G P+ GG + GA T AA
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131
Score = 73.6 bits (179), Expect = 6e-13
Identities = 126/525 (24%), Positives = 170/525 (32%), Gaps = 81/525 (15%)
Query: 53 GSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPA---GTLLPG-- 107
G+ TPP P P+ SP T P P + PP + P P+ G P
Sbjct: 1308 GAPTPPAA-TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366
Query: 108 ---------PSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKD--T 156
PS PA TP R S +G P++ PL P P ++
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA 1426
Query: 157 VPRAPSQFPP---PLETWKPPPPLPSERQPA--DRRITPALATPASPPTESQAGPRNQGQ 211
P PP P+ K P + PA + P L P + P+
Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486
Query: 212 TAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGG 271
++ + A P A G PA S + R +AP A S A+L
Sbjct: 1487 SSSPKKAPATP-APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAP- 1544
Query: 272 GGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGA---QEAEGGDGDGEGCSGPPSA 328
K+ +PP P + + +EA E S P
Sbjct: 1545 ------------------KEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586
Query: 329 PASQARALPP-----PPYTTFPGSK--PKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAA 381
P++ A P PP T P K P V+ P PE+ G +P +
Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS-PEKGPATPAPKGTPTSPPVTPS 1645
Query: 382 ALSGPWGSP-----------PPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPG 430
+L SP P + + + GP L+AP P T P R G
Sbjct: 1646 SLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT--APTRKG 1703
Query: 431 PPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTP----------GLGHKESALAPTA 480
P + PP P P+ + + P PL P G S P A
Sbjct: 1704 PQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLA 1763
Query: 481 AP----ALPPALAADQAPAPSPAPAPTVAEPSPPVSAP-APAAAP 520
P + P AA + P P A A PSPPVS P AP+ P
Sbjct: 1764 PPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVP 1808
Score = 73.2 bits (178), Expect = 7e-13
Identities = 138/606 (22%), Positives = 208/606 (34%), Gaps = 112/606 (18%)
Query: 8 PSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQ 67
P+A S K P P T P +T + + T L P S P +E
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTP---PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369
Query: 68 ASPSTLPLTLERPSPVMPPPEEAAAVSAP---PPAPA-----------------GTLLPG 107
P+ P P+ P P+ A+ +P P +PA G P
Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS 1429
Query: 108 PSKWQKPAGTPVPRIRRLLEASHRG-------QGDP--PSLRPLKP--PPPPRQLSVKDT 156
PA TPV + ++ +G +GDP P++ P P PP P+Q++ +
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489
Query: 157 VPRAPSQFPPPL----------ETWKPPPPLPSERQ-------------------PADRR 187
+AP+ P P+ + K P PS R+ P +
Sbjct: 1490 PKKAPAT-PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548
Query: 188 ITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITF 247
I PA+ P+ T + P+ T +PP A + A S L + +T
Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP-AVTPSTYKGAPSPKELLIPPAVTS 1607
Query: 248 KS------RPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPP----- 296
S P++ PP+ A A G + +S LK P P
Sbjct: 1608 PSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS--------LKDSPTSPASVTC 1659
Query: 297 --GAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWV 354
GA P + S+G +G E APA ++ + P P +K K
Sbjct: 1660 KMGATVP--QASKGLPAKKGPTALKEVL----VAPAPESTPIITAPTRKGPQTK-KSSAT 1712
Query: 355 SAPDGPERHFRFNGAGGGIGA-------PRRRAAALSGPWGSPPPPPEQIHSAPGPRRPA 407
S P P+ + NG+ G + P ++ ++ + P+ + P +
Sbjct: 1713 SPPICPDPSAK-NGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST 1771
Query: 408 PALLAPPTFIFPAPTNGE-PMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLT 466
P A + P P + P PP L P P PT PP Q LP +P L
Sbjct: 1772 PLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQ-------FLPSSPGLV 1824
Query: 467 PGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSP-PVSAPAPAAAPIKTRT 525
L LAP L P + + P + V P+P P P + + T
Sbjct: 1825 --LESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVT 1882
Query: 526 RRNKGS 531
+ NKGS
Sbjct: 1883 KNNKGS 1888
Score = 33.9 bits (76), Expect = 0.48
Identities = 112/523 (21%), Positives = 170/523 (32%), Gaps = 91/523 (17%)
Query: 52 PGSATPPGLMVPRE---PQASPSTLPLT--------LERPSPVMPPPEEAAAVSAP-PPA 99
PG AT +E PQA + LP++ L +P P +PPP A P A
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 100 PAGTLLPGPSK-WQKPAGTPVPRIRRLLEASHRGQGDPPSLRP--LKPPPPPRQLS---- 152
+ P PS P P P+ + P+ P + PP P L+
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121
Query: 153 -VKDTVPRAPSQ-------------------FPPPLETWKPPPPLPSERQPADRRITPAL 192
+ T+ PS FPP L T PP + + A
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLT---SPPSVAVAESGSVITLSAP 178
Query: 193 ATPASPPTE-----SQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITF 247
P+ P T S+ P +G + P+ M A +SG++ L + T
Sbjct: 179 IAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPM---ASIQSGVASLPQTTP 235
Query: 248 KSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSR 307
+ ++A P + + + G L +GP+ P AA L S
Sbjct: 236 TTTLAIASPQVKDTTISSVLISPQNPGSLSL------------KGPVSPPAALSLSTQSL 283
Query: 308 GAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWV---SAPDGPERHF 364
+ G + PP P S L P ++F GS + D +
Sbjct: 284 PVVTSSQKTA---GPNTPPDFPISLGSHLAPLHQSSF-GSVQLLGQTGPSALSDPTVKTI 339
Query: 365 RFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNG 424
+ + G P +R+ PP P + P P ++AP + P+
Sbjct: 340 SVDHSSTGASYPSQRSVI--------PPLPSRNEVVPATVAAFP-VVAPS--VDKGPSTI 388
Query: 425 EPMRPGPPGLQELPPLPPPTPPPTL----QPPALQPTPLPVAPPL-----TPGLGHKESA 475
+ P G + +P +L P A PL P+ TP +
Sbjct: 389 SSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCT 448
Query: 476 LAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAA 518
+A AAP +A +P S P + SP AP A
Sbjct: 449 IA--AAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVA 489
Score = 32.7 bits (73), Expect = 1.1
Identities = 35/136 (25%), Positives = 51/136 (37%), Gaps = 7/136 (5%)
Query: 386 PWGSPPPPPEQIHSAPGPR-RPAPALLAPPTFIFPAPT-NGEPMRPGPPGLQELPPLPPP 443
P G+ P P + + GP PA LA P APT G P P L L P
Sbjct: 92 PLGTAPEAPTFLPNLIGPPISPAALALASPMI---APTLKGTPSSSAPLALVALAP--HS 146
Query: 444 TPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPT 503
+ PP L +P VA + + + +AP+ + ++ P P P+P
Sbjct: 147 VQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPP 206
Query: 504 VAEPSPPVSAPAPAAA 519
+ P P A+
Sbjct: 207 CIVSTVPYHCVTPMAS 222
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 102 bits (253), Expect = 1e-21
Identities = 165/616 (26%), Positives = 217/616 (35%), Gaps = 119/616 (19%)
Query: 8 PSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQ 67
PSAGGG ++ P+ R+ S T L P + + R T P P GL R PQ
Sbjct: 219 PSAGGGLQR--PASRSLSSSATPLSSPARSGPSARGTPRAPA-HPSQPKPKGLQALRPPQ 275
Query: 68 -------ASPSTLPLT---LERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGT 117
A+P+ PL+ L PSP PP A P+P T PS+ G+
Sbjct: 276 VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT---PPSQATTSLGS 332
Query: 118 PVPRIRRLLEASHRGQGDPPSLRPLKPPPP--PRQLSVKDT-VPRAPSQFPP--PLETWK 172
P L+A+H PP L PL PPP P L++ P +P PP PL T
Sbjct: 333 PT------LQATHSFLPSPP-LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385
Query: 173 P----------------PPPLPSERQPADRRITPALATPASPPTE---SQAGPRNQGQTA 213
P PPP P + P +P ++ A+PP++ S A P Q +
Sbjct: 386 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445
Query: 214 GRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGG 273
A P A A P + L L K ++ P+LA P + + AS G
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQL-AKPPPQAPPALATPPLQALPSPPASFPGQAP 504
Query: 274 GGLFAASGAISYAEVLKQGP-LPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQ 332
F+ S ++ + + P PP A PL +V PP++P Q
Sbjct: 505 ---FSPSASLPMSPLATPPPQAPPVLAAPLLQVP----------------PSPPASPTLQ 545
Query: 333 ARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPP 392
A PP P GP+ + PR A GP PP
Sbjct: 546 APRRPPTP------------------GPDT---------SVSGPRLTLALAPGP----PP 574
Query: 393 PPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPP 452
PP + +P P L + P GP G P PP P
Sbjct: 575 PPSR---SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP-PPDAELAACHPA 630
Query: 453 ALQPTPLPVAPPLT----PGLGHK-ESALAPTAAPALPPALAADQAPAPSPAPAPTVAEP 507
A P APPL PG A P +A L + + +PAP P
Sbjct: 631 AWSRGP---APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 687
Query: 508 SPPVSA-PAPAAAPIKTRTRRNKGSRAAR---GATRKDGLHGDGPRE----RATATVPDS 559
SP S A A A +R K +R GA + + R A S
Sbjct: 688 SPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGS 747
Query: 560 SGGGGGGSGASQTGAA 575
GG GG G TG A
Sbjct: 748 GGGPGGAEGGGVTGGA 763
Score = 99.4 bits (246), Expect = 9e-21
Identities = 167/625 (26%), Positives = 213/625 (34%), Gaps = 144/625 (23%)
Query: 54 SATPPGLMVPREPQASPSTLPLTLERPSPVMPPPE-----EAAAVSAPPPAP-----AGT 103
+A PGL+ PR P SP RP P + P A AV P A G
Sbjct: 18 AARAPGLLTPR-PPGSP--------RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 104 LLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPP----SLRPLKPP--------PPP--- 148
+P + P T P AS RG+ PP S P+ P P P
Sbjct: 69 TIPESAPRAGPTRTSRP------PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 122
Query: 149 --RQLSVKDTVPRAPSQFPPP---------LETWKPPPPLPSERQPADRRIT-------- 189
++S ++TV R + P +T P P PS R
Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182
Query: 190 PALATPASPPTESQAGPRNQGQTAGRARGGAP-------PHAGEGEMAQPADSESGLSLL 242
PA + PPTE GPR +A P P AG G + +PA SL
Sbjct: 183 PAPSARPRPPTE---GPRKSVSSASEHSTTEPSPAARRRPSAG-GGLQRPASR----SLS 234
Query: 243 CKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGP-LPPGAARP 301
T S P+ + P+A + A A GL A P L P ++ P
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294
Query: 302 LGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARA-------------LPPPPYTTFPGSK 348
L S A + + PP+ P SQA LP PP +
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 354
Query: 349 PK------FDWVSAPDGPERHFRFNG-AGGGIGAPRRRAA-ALSGPWGSPPPPPEQI--- 397
P+ + AP P + A AP A L P+ PP PP Q
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 398 --------HSAPGPRRPAPALLAPPTFIFPAPTNGEPMRP-GPPGLQELPPL-------- 440
SA P + P+L APP + P+P PM P P Q PPL
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 474
Query: 441 -PPPTPPPTLQPPALQPTPLPVA-----PPLTPGLGHKESALA---PTAAPAL------- 484
PPP PP L P LQ P P A P +P S LA P A P L
Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534
Query: 485 ---PPALAADQAPAPSPAPAPTVAEPSP-------PVSAPAPAAAPIKTRTRRNKGSRAA 534
PPA QAP P P P + P P P P+ +P T + + ++
Sbjct: 535 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 594
Query: 535 RGATRKDGLHG--DGPRERATATVP 557
+ + L G GP A A+ P
Sbjct: 595 SATSTPEELRGYDSGPEGGAAASPP 619
Score = 47.8 bits (112), Expect = 3e-05
Identities = 63/244 (25%), Positives = 83/244 (34%), Gaps = 24/244 (9%)
Query: 325 PPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALS 384
PP +P PPPP T + A R AGG GA +A +
Sbjct: 29 PPGSPR------PPPPVTP-----AALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 385 GPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPT 444
GP + PP S G R P +P P +G RPGP G + L T
Sbjct: 78 GPTRTSRPPA----SGRGERAPPAKNTSPGPVSSPGRASGTT-RPGPLGQKGLRISAEET 132
Query: 445 PPPTLQPPALQPTPLPVAPPLTPGLGHKESALAP-TAAPALPPALAADQAPAPSPAPAPT 503
+ T P L+ G S P T +PA+ A P PAP+
Sbjct: 133 VARG------KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 186
Query: 504 VAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGG 563
A P PP P + + + A R + GL R +++ P SS
Sbjct: 187 -ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245
Query: 564 GGGS 567
G S
Sbjct: 246 SGPS 249
Score = 43.9 bits (102), Expect = 5e-04
Identities = 45/155 (29%), Positives = 58/155 (37%), Gaps = 8/155 (5%)
Query: 432 PGLQELPPLPP--PTPPPTLQPPALQPTPLPVA---PPLTPGLGHKESALAPTAAPALPP 486
PGL L P PP P PPP + P AL+ A PL G A P +AP P
Sbjct: 22 PGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGP 79
Query: 487 ALAADQAPAPSPAPAPTVAEPSP-PVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHG 545
+ + AP SP PVS+P A+ + KG R + T G
Sbjct: 80 TRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 139
Query: 546 DGPRERATATVPDSSGGGGGGSGASQTGAANTRAA 580
+ P+ A + G S A +RAA
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 174
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 99.8 bits (247), Expect = 7e-21
Identities = 159/625 (25%), Positives = 218/625 (34%), Gaps = 120/625 (19%)
Query: 8 PSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQ 67
P+ G+ P+ R P S R P + PG + PG +
Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAPPAKNTS------------PGPVSSPG-------R 119
Query: 68 ASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPA---GTPVPRIRR 124
AS +T P L + + EE A AP + L ++ GTP P + R
Sbjct: 120 ASGTTRPGPLGQKG-LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR 178
Query: 125 LLEASHRGQGDP---PSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSER 181
A+ G P PS RP P PR+ SV + ++ P P +P +R
Sbjct: 179 RSRAAGTEVGLPRPAPSARPRPPTEGPRK-SVSSASEHSTTE-PSPAARRRPSAGGGLQR 236
Query: 182 QPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSL 241
PA R ++ + ATP S P S GP +G A P G + P +
Sbjct: 237 -PASRSLSSS-ATPLSSPARS--GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
Query: 242 LCKITFKSRPSLAPPAASSSLAAKA-----------SLGGGGGGGLFAASGAISYAEVLK 290
+ S LA P+ S++L ++A SL L A + S L+
Sbjct: 293 APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ 352
Query: 291 QGPLPPGAARPLGEVSRGAQEAEGGDGDGEG------CSGPPSAPASQARALPPPPYTTF 344
P PP S G+ + + PP AP A ALPP
Sbjct: 353 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP--ALALPPLQAPPS 410
Query: 345 PGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAA-ALSGPWGSPPPPPEQIH----- 398
P + P ++ P P+ AP A L P+ PP PP Q
Sbjct: 411 PPASPPLSPLATPS-PQ-------------APNALAVHLLQAPFSPPPSPPVQAPFSPPA 456
Query: 399 ------SAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGP-PGLQELPPL---------PP 442
SA P + P+L APP + P+P PM P P Q PPL PP
Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516
Query: 443 PTPPPTLQPPALQPTPLPVA----------------------PPLTPGLGHKESALAPTA 480
P PP L P LQ P P A PP P + P +
Sbjct: 517 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 576
Query: 481 APALPPALAADQAPAPSP-----APAPTVA-EPSPPVSAPAPAAAPIKTRTRRNKGSRAA 534
PA P A + P P P P T+A P PP P P+ +P T + + ++
Sbjct: 577 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGPDLAGHSS 633
Query: 535 RGATRKDGLHG--DGPRERATATVP 557
+ + L G GP A A+ P
Sbjct: 634 SATSTPEELRGYDSGPEGGAAASPP 658
Score = 96.7 bits (239), Expect = 6e-20
Identities = 154/634 (24%), Positives = 215/634 (33%), Gaps = 133/634 (20%)
Query: 8 PSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQ 67
PSAGGG ++ P+ R+ S T L P + + R T P P GL R PQ
Sbjct: 228 PSAGGGLQR--PASRSLSSSATPLSSPARSGPSARGTPRAPA-HPSQPKPKGLQALRPPQ 284
Query: 68 ASP------------STLPLTLERPS--------PVMPPPEEAAAVSAPPPAPAGTLLPG 107
+P S+ PL PS P +P +++++ P P
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS 344
Query: 108 PSK------WQKPAGTPVPRIRR-----LLEASHRGQGDPPSLRPLKPPPP--PRQLSVK 154
PS P TP + L+A+H PP L PL PPP P L++
Sbjct: 345 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LSPLATPPPQAPPALALP 403
Query: 155 DT-VPRAPSQFPP--PLETWKP----------------PPPLPSERQPADRRITPALATP 195
P +P PP PL T P PPP P + P +P ++
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463
Query: 196 ASPPTE---SQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPS 252
A+PP++ S A P Q + A P A A P + L L K ++ P+
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL-AKPPPQAPPA 522
Query: 253 LAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGP-LPPGAARPLGEVSRGAQE 311
LA P + + AS G F+ S ++ + + P PP A PL +V
Sbjct: 523 LATPPLQALPSPPASFPGQAP---FSPSASLPMSPLATPPPQAPPVLAAPLLQVP----- 574
Query: 312 AEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGG 371
PP++P QA PP P GP+
Sbjct: 575 -----------PSPPASPTLQAPRRPPTP------------------GPDT--------- 596
Query: 372 GIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGP 431
+ PR A GP PPPP + +P P L + P GP
Sbjct: 597 SVSGPRLTLALAPGP----PPPPSR---SPSSTLSGPDLAGHSSSATSTPEELRGYDSGP 649
Query: 432 PGLQELPPLPPPT------------PPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPT 479
G P P P P L PLP P PG + T
Sbjct: 650 EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET 709
Query: 480 AAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATR 539
P A A A P P+P + + + A A + +P + R GA +
Sbjct: 710 EGP--ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL-----GELPLGALQ 762
Query: 540 KDGLHGDGPRERATATVPDSSGGGGGGSGASQTG 573
+ R A ++GG GGG G ++ G
Sbjct: 763 ASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGG 796
Score = 83.2 bits (204), Expect = 7e-16
Identities = 124/453 (27%), Positives = 159/453 (35%), Gaps = 97/453 (21%)
Query: 159 RAPSQFPP-PLETWKPPPPLPSE------------RQPADRRITPALATPASPPTESQAG 205
RAP P P + +PPPP+ R+P R + P + +AG
Sbjct: 20 RAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER-AGGIGGATIPESAPRAG 78
Query: 206 PRNQGQTAGRARGGAPPHAGEGEMAQPADSES----------------------GLSLLC 243
P T+ R PP +G GE A PA + S GL +
Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 244 KITF-KSRPSLAPPAASSSLAAKASLGG---GGGGGLFAASGAISYAEVLKQGPLPPGAA 299
+ T + + + AP ++ S A+ G G A + EV P P
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198
Query: 300 RPLGEVSR----GAQE---------AEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPG 346
RP E R A E A G G P S S + P + P
Sbjct: 199 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258
Query: 347 SKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGS----PPPPPEQIHSAPG 402
++ + P P+ + PR+ AA GP S P P + S
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318
Query: 403 PRRPA-------------PALLAPPTFIFPAPTNGEPMRP-----------GPPGLQEL- 437
P PA P LAPP+ P P P G P LQ
Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 378
Query: 438 -----PPLPPPTPPPTLQPPALQPTPL--PVAPPLTPGLGHKESALAPTAAPALPPALAA 490
PPL P PP PPAL PL P +PP +P L S LA T +P P ALA
Sbjct: 379 SFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL----SPLA-TPSPQAPNALAV 433
Query: 491 DQAPAP-SPAPAPTVAEP-SPPVSAP-APAAAP 520
AP SP P+P V P SPP S P +P+A P
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466
Score = 45.4 bits (106), Expect = 2e-04
Identities = 64/251 (25%), Positives = 81/251 (32%), Gaps = 29/251 (11%)
Query: 325 PPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGI-------GAPR 377
PP +P PPPP T P + A R G GG P
Sbjct: 29 PPGSPR------PPPPVT--PAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80
Query: 378 RRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQEL 437
R A S S PP S G R P +P P +G RPGP G + L
Sbjct: 81 RSAGTSSRNPASRPPA-----SGRGERAPPAKNTSPGPVSSPGRASGTT-RPGPLGQKGL 134
Query: 438 PPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAP-TAAPALPPALAADQAPAP 496
T + T P L+ G S P T +PA+ A
Sbjct: 135 RISAEETVARG------KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 497 SPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATV 556
P PAP+ A P PP P + + + A R + GL R +++
Sbjct: 189 LPRPAPS-ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 557 PDSSGGGGGGS 567
P SS G S
Sbjct: 248 PLSSPARSGPS 258
Score = 43.1 bits (100), Expect = 8e-04
Identities = 49/164 (29%), Positives = 62/164 (37%), Gaps = 17/164 (10%)
Query: 432 PGLQELPPLPP--PTPPPTLQPPALQPTPLPVA---PPLTPGLGHKESALAPTAAPALPP 486
PGL L P PP P PPP + P AL+ A PL G A P +AP P
Sbjct: 22 PGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGP 79
Query: 487 ALAADQA---PAPSPAP------APTVAEPSP-PVSAPAPAAAPIKTRTRRNKGSRAARG 536
+A + PA P AP SP PVS+P A+ + KG R +
Sbjct: 80 TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
Query: 537 ATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAA 580
T G + P+ A + G S A +RAA
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 98.2 bits (243), Expect = 2e-20
Identities = 158/655 (24%), Positives = 215/655 (32%), Gaps = 155/655 (23%)
Query: 5 QSEPSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPR 64
+ + S GG +R + S P SQ L G P TPP P
Sbjct: 691 RQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEG-----PAPGTPPREARPG 745
Query: 65 EPQAS--PSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRI 122
S +++P +P V+PP + PP P T P P G P P
Sbjct: 746 RHGHSIKRASVPPVPGKPRQVLPP---GTSHFTPPQTPTKTRPGSPQALGGPHG-PAPAT 801
Query: 123 RRLLEASHRGQGDPPSLRPLKPPPPPRQLSVK------------DTVPRAPSQFPPPLET 170
++ Q PP+ RP+ P P+ + + + P AP PPP+ T
Sbjct: 802 AKVKPTP---QLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPT 858
Query: 171 WKPPPPLP----------------------SERQPA-DRRITPALATPASPP------TE 201
P LP S+ +P D + PA A P + +
Sbjct: 859 AVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSH 918
Query: 202 SQAGPRNQGQTAGRARGGA-----------PPHAGEGEMA------------QPADSESG 238
S P + R++ A PP +A +P D G
Sbjct: 919 SVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLG 978
Query: 239 LSLLCKITFKSRPSLAPPAASS--SLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPP 296
+ C+ S+ +A S S+AA L GGGG A + P P
Sbjct: 979 VRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASPEPG 1038
Query: 297 GAARPLGEVSRGAQEAEGGD---------------------GDGEGCS-GP--------- 325
A L V GG+ G GE GP
Sbjct: 1039 RVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGRQ 1098
Query: 326 -PSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALS 384
P P+ + PP S + A + + +F +RR A
Sbjct: 1099 RPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESD--TVKRRPKAKE 1156
Query: 385 GPWGSPPPPPEQI-HSAPGP--RRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLP 441
G PPPP + H+ G RRPA PP P P P P P L LPPLP
Sbjct: 1157 REAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPP----PAEPPPTDLAHLPPLP 1212
Query: 442 PP------------TPPPTL-QP-PALQPTPLPVA--------------------PPLTP 467
PP +P P L QP P LQ +P P + PP++P
Sbjct: 1213 PPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSP 1272
Query: 468 GLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIK 522
+A P A A P+ +A +PAPSPA P A PP + P+ A+P K
Sbjct: 1273 KPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAK 1327
Score = 56.6 bits (135), Expect = 7e-08
Identities = 60/218 (27%), Positives = 79/218 (36%), Gaps = 26/218 (11%)
Query: 53 GSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGP---S 109
G PP L V + P + + P +PPP A PPP L P P
Sbjct: 1160 GPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPA---EPPPTDLAHLPPLPPPEG 1216
Query: 110 KWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLE 169
+ +KPA PV L + + QG P P P P VK RA PPP+
Sbjct: 1217 EARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVK----RAHGT-PPPVS 1271
Query: 170 TWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEM 229
PPPP + A + A P+ P+ P Q A G PP G
Sbjct: 1272 PKPPPPPTAPKPVKAVAGLPSGSAGPSPAPS-----PARQPPAALAKPPGTPPSLGASPA 1326
Query: 230 AQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKAS 267
P+ L + K PP A+++ AA A+
Sbjct: 1327 KPPSPGAPALHVPAK----------PPRAAAAAAAAAA 1354
Score = 55.5 bits (132), Expect = 2e-07
Identities = 61/205 (29%), Positives = 70/205 (34%), Gaps = 49/205 (23%)
Query: 63 PREPQASPSTLPLTLERPSP-------------VMPPPEEAAAVSAPPPAPAGTLLPGPS 109
P QA P LP P P +PPPE A A PP +L P
Sbjct: 1181 PASEQAGPPELP----PPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPV 1236
Query: 110 KWQKPAGTPVPRIRRL------LEASHRGQGDPPSLRPLKPPPPPRQLSVKDTV-----P 158
K G+P P +++ R G PP + P PPPP VK
Sbjct: 1237 --PKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGS 1294
Query: 159 RAPSQFP-----PPLETWKP---PPPLPSERQPADRRITPALATPASPPTESQAGPRNQG 210
PS P PP KP PP L + PAL PA PP +
Sbjct: 1295 AGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPP---------RA 1345
Query: 211 QTAGRARGGAPPHAGEGEMAQPADS 235
A A APP EG A P DS
Sbjct: 1346 AAAAAAAAAAPPAPPEG--ASPGDS 1368
Score = 42.4 bits (98), Expect = 0.001
Identities = 92/392 (23%), Positives = 135/392 (34%), Gaps = 67/392 (17%)
Query: 70 PSTLPLTLERPSPVMPPPEEAAAVS-------APPPAPAGTLL----PGPSKWQKPAGTP 118
P+ + T E+PS +PP A A + + LL PGPS +P
Sbjct: 668 PAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPS-------SP 720
Query: 119 VPRIRRLLEASHRGQGDPP-SLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPL 177
+ R + L G PP RP + ++ SV VP P Q PP + PP
Sbjct: 721 MSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPP-VPGKPRQVLPPGTSHFTPPQT 779
Query: 178 PSERQPADRRIT-----PALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEG-EMAQ 231
P++ +P + PA AT PT Q P + + R+ +P H G + Q
Sbjct: 780 PTKTRPGSPQALGGPHGPAPATAKVKPT-PQLLPPTERPMSPRSLPQSPTHRGFAYVLPQ 838
Query: 232 PADSESGLSLLCKITFKSRPSLAPPAASSSL-------AAKASLGGGGGGGLFAASGAIS 284
P + E G + P APP +++ A A G A S
Sbjct: 839 PVEGEVG---------PAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAAS 889
Query: 285 YAEVLKQGPLPPGAARPLGEVSR------GAQEAEGGDGDGEGCSGPPSAPASQARALPP 338
+E + L P AA P V R + G D + P + PP
Sbjct: 890 DSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPP 949
Query: 339 PPYTT------------FPGSKPKFDWVSAPDGPERHFRFNGA--GGGIGAPRRRAAALS 384
P ++ P ++P+ + R G+ G G+ + AA L
Sbjct: 950 PKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLE 1009
Query: 385 ----GPWGSPPPPPEQIHSAPGPRRPAPALLA 412
G G P + H P P P P +A
Sbjct: 1010 LSSIGGGGRAARRPPEGHPTPRPASPEPGRVA 1041
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/189 (28%), Positives = 66/189 (34%), Gaps = 27/189 (14%)
Query: 385 GPWGSPPP----PPEQIHSA------PGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGL 434
GP PP P HS P P +P +L P T F P RPG P
Sbjct: 732 GPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQ-VLPPGTSHFTPPQTPTKTRPGSPQA 790
Query: 435 QELPPLPPP-TPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQA 493
P P P T P L PT P++P P +S A LP + +
Sbjct: 791 LGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLP-----QSPTHRGFAYVLPQPVEGEVG 845
Query: 494 P-APSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERA 552
P AP PAP P P A P + + R + +R A D ER
Sbjct: 846 PAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAA---------SDSEPERD 896
Query: 553 TATVPDSSG 561
VP ++G
Sbjct: 897 ELLVPAAAG 905
Score = 36.6 bits (83), Expect = 0.075
Identities = 40/160 (25%), Positives = 52/160 (32%), Gaps = 43/160 (26%)
Query: 402 GPRRPAPALLAPPTFIFPAP------------------TNGEPMRPGPPG---------- 433
GP P P + + P P ++ E + GPPG
Sbjct: 667 GPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQE 726
Query: 434 --LQELPPLPPPTPPPTLQP---------PALQPTPLPVAPPLTPGLGHKESALAPTAA- 481
L E P P TPP +P ++ P P L PG H PT
Sbjct: 727 YLLDEGPA--PGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTR 784
Query: 482 PALPPALAADQAPAPSPAPAPTVAEPSPPVSAP-APAAAP 520
P P AL PAP+ A + PP P +P + P
Sbjct: 785 PGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLP 824
Score = 34.3 bits (77), Expect = 0.37
Identities = 39/144 (27%), Positives = 49/144 (34%), Gaps = 23/144 (15%)
Query: 24 PDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQASPSTLPLTLERPSPV 83
P S++ L P + + R G P S PP +P + + LP PSP
Sbjct: 1245 PTSKKVPLPGPG----SPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPA 1300
Query: 84 MPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLK 143
P + A A PP GT PS PA P P G P P K
Sbjct: 1301 PSPARQPPAALAKPP---GT---PPSLGASPAKPPSP-------------GAPALHVPAK 1341
Query: 144 PPPPPRQLSVKDTVPRAPSQFPPP 167
PP + P AP + P
Sbjct: 1342 PPRAAAAAAAAAAAPPAPPEGASP 1365
Score = 34.3 bits (77), Expect = 0.37
Identities = 36/122 (29%), Positives = 45/122 (36%), Gaps = 16/122 (13%)
Query: 8 PSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGL--GVWFPGSATPPGLMVP-- 63
P G GS +V+ + P P + ++ GL G P A P P
Sbjct: 1251 PLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAA 1310
Query: 64 --REPQASPSTLPLTLERPSPVMP-------PPEEAAAVSA---PPPAPAGTLLPGPSKW 111
+ P PS + PSP P PP AAA +A PPAP PG S
Sbjct: 1311 LAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSAR 1370
Query: 112 QK 113
QK
Sbjct: 1371 QK 1372
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 97.8 bits (242), Expect = 3e-20
Identities = 149/569 (26%), Positives = 195/569 (34%), Gaps = 94/569 (16%)
Query: 8 PSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQ 67
P A SR ++ S +P + L P +S L S P L P P
Sbjct: 480 PEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPP 539
Query: 68 ASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW------QKPAGTPVPR 121
S L E SP+ PPPEE + PP A L P P + ++ +P P
Sbjct: 540 PEASPLSPPFEE-SPLSPPPEE---LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE 595
Query: 122 IRRLLEASHRGQ-GDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSE 180
RL PP PL PPP +LS P PPP E+ PPP S
Sbjct: 596 ASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP---PEDSPMSPPPEESPMSPPPEVSR 652
Query: 181 RQP---ADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAG------EGEMAQ 231
P R P +P SPP E P + A R PP E A
Sbjct: 653 LSPLPVVSRLSPPPEESPLSPPPEES--PTSPPPEASRL--SPPPEDSPTSPPPEDSPAS 708
Query: 232 PADSESGLSLLCK----ITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAE 287
P +S +SL + + P L P + L+ +
Sbjct: 709 PPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP--------------------- 747
Query: 288 VLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGC-----SGPPSAPASQARALPPPP-- 340
++ L P P +S A+E E C P +P ++ L P P
Sbjct: 748 --EEPHLSPRPEEP--HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEE 803
Query: 341 -----YTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPP--PP 393
T P P + PE + +PR + LS PP P
Sbjct: 804 LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPR 863
Query: 394 PEQIHSAPGPRRPAPA---LLAPPTFIFPAPTNGEPM--RPGPPGLQELPPLPP--PTPP 446
PE+ PG + PAP L PP +P GEP PG P L LP P P+
Sbjct: 864 PEKPPEEPG-QCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGE 922
Query: 447 PTLQPPALQPTPLPVAPPLTPGL-GHKESALAPTAAPALPPALAADQAP----------- 494
P+L P + P PLP PPL+P + AL+P P D P
Sbjct: 923 PSLSPQLMPPDPLP--PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILET 980
Query: 495 --APSPAPAPTVAEPSPPVSAPAPAAAPI 521
+P P T EP PP+ P +P+
Sbjct: 981 PISPPPEANCTDPEPVPPMILPPSPGSPV 1009
Score = 85.1 bits (209), Expect = 2e-16
Identities = 143/530 (26%), Positives = 190/530 (35%), Gaps = 106/530 (20%)
Query: 62 VPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAP------PPAPAGTLLPGPSKWQKPA 115
V EPQ L L P++PPPEE+ P PP A L P P + PA
Sbjct: 424 VQLEPQ-----LEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPE--ELPA 476
Query: 116 GTPVPR---IRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPP---LE 169
+P+P + R LE S PP PL PPP S + P +P + PP LE
Sbjct: 477 -SPLPEALHLSRPLEESPLSP--PPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALE 533
Query: 170 TWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEM 229
T PPP S P P +P SPP E P + A R PP E M
Sbjct: 534 TPLSPPPEASPLSP------PFEESPLSPPPEEL--PTSPPPEASRL--SPPPE--ESPM 581
Query: 230 AQPADSESGLSLLCKIT-----FKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAIS 284
+ P + ES +S + + F+ P L+PP S L+ L
Sbjct: 582 SPPPE-ESPMSPPPEASRLFPPFEESP-LSPPPEESPLSPPPE-----ASRLSPPPEDSP 634
Query: 285 YAEVLKQGPL--PPGAAR--PLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPP-- 338
+ ++ P+ PP +R PL VSR + E P S P +R PP
Sbjct: 635 MSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPE 694
Query: 339 -----PPYTTFPGSKPKFDWVSA-----------PDGPERHFRFNGAGGGIGAPRRRAAA 382
PP P S P D + + P+ P+ R G +PR
Sbjct: 695 DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPH---LSPRPEEPH 751
Query: 383 LSGPWGSP--PPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPL 440
LS P P E+ H +P P P + + P G + P P L P
Sbjct: 752 LSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP-QAEGPHLSPQPEELHLSPQT 810
Query: 441 PPPTPPPTLQPPALQP-------TPLPVAPPLTPGLGHKESALAP-------TAAPALPP 486
P P + P L P +P P L+P +ES L+P + P PP
Sbjct: 811 EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSP--RPEESHLSPELEKPPLSPRPEKPP 868
Query: 487 ALAADQAPAPSPAP---------------APTVAEPSPPVSAPAPAAAPI 521
Q PAP P P ++EP P +P P P+
Sbjct: 869 E-EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPL 917
Score = 73.6 bits (179), Expect = 6e-13
Identities = 141/553 (25%), Positives = 178/553 (32%), Gaps = 130/553 (23%)
Query: 56 TPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPA 115
+PP P P S L E SP+ PPPEE+ +S PP A + P S P
Sbjct: 582 SPPPEESPMSPPPEASRLFPPFEE-SPLSPPPEESP-LSPPPEASRLSPPPEDSPMSPPP 639
Query: 116 G----TPVPRIRRLLEASHRGQ-GDPPSLRPLKPPP------PPRQLSVKDTVPRAPSQF 164
+P P + RL + PP PL PPP PP + S P
Sbjct: 640 EESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS 699
Query: 165 PPPLETWKPPPP----------------LPSERQPADRRITPALAT----------PASP 198
PPP ++ PPP LP E Q R P L+ P P
Sbjct: 700 PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEP 759
Query: 199 PTESQAG-PRNQGQTAGRARGGAP--PHAG---EGEMAQPADSESGLSLLCKITFKS--- 249
QA P Q P PH EG P E LS + S
Sbjct: 760 HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819
Query: 250 -RPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRG 308
P L+P S L+ ++ L + L++ PL P +P E +
Sbjct: 820 EEPCLSPQPEESHLSPQSE-----EPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQC 874
Query: 309 AQEAE------GGDGDGEGCSGPP--SAPASQARALPPPPYTTFPGSKPKFDWVSAPDGP 360
E G+ G P S P + P P +P P P
Sbjct: 875 PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDP 934
Query: 361 ---------------------ERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHS 399
E + F G A L P PPPE +
Sbjct: 935 LPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPIS---PPPEANCT 991
Query: 400 APGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQE-LPP----------LPPPTPPPT 448
P P PP + P+P G P+ P P L E LPP +P +PP
Sbjct: 992 DPEP--------VPPMILPPSP--GSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQ 1041
Query: 449 LQPPALQPTPLPVAPPLTP-----GLGHKES---------------ALAPTAAPALPPAL 488
PPAL PL V PL+P G+ + AL P+A LP +
Sbjct: 1042 CSPPAL---PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPM 1098
Query: 489 AADQAPAPSPAPA 501
PAPSPAPA
Sbjct: 1099 GDLSCPAPSPAPA 1111
Score = 63.9 bits (154), Expect = 4e-10
Identities = 121/483 (25%), Positives = 156/483 (32%), Gaps = 98/483 (20%)
Query: 78 ERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPP 137
+RP+ + P + A+ +PPPA A T+ G T + S G P
Sbjct: 2098 DRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPG 2157
Query: 138 SLRPLKPPPPPRQLSVKDTV------------PRAPSQFPP-PLETWKP--PPPL----- 177
L PP P Q+ +D P AP +PP P T P PP L
Sbjct: 2158 ELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSR 2217
Query: 178 PSERQPADRRITPA------------LATPASPPTESQAGPRNQGQTAGRARGG--APPH 223
P QP + TP P P ++ A P + G G+A +PP
Sbjct: 2218 PGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277
Query: 224 AGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAI 283
GE A E S PS PP + G GGL +
Sbjct: 2278 FGESRKALEVKKEE--------LGASSPSYGPPNLGF---VDSPSSGTHLGGL-----EL 2321
Query: 284 SYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYT- 342
+V K PL P R +Q G G P P +QA A PP +
Sbjct: 2322 KTPDVFK-APLTP----------RASQVEPQSPGLG---LRPQEPPPAQALAPSPPSHPD 2367
Query: 343 -------TFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPE 395
T P ++P P PE P R S P+ P P+
Sbjct: 2368 IFRPGSYTDPYAQPPLTPRPQPPPPE---------SCCALPPRSLP--SDPFSRVPASPQ 2416
Query: 396 QIHSAPGPRRPAPALL-------APPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPT 448
S+ P P P P F P P + P RP Q P P PP
Sbjct: 2417 SQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP-----QSRDPFAPLHKPPR 2471
Query: 449 LQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAP--APSPAPAPTVAE 506
QPP + +A + G G +AL A L + + Q P SP V
Sbjct: 2472 PQPPEVAFKAGSLA-HTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGT 2530
Query: 507 PSP 509
PSP
Sbjct: 2531 PSP 2533
Score = 53.5 bits (127), Expect = 6e-07
Identities = 65/261 (24%), Positives = 84/261 (32%), Gaps = 44/261 (16%)
Query: 293 PLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFD 352
P P P GA G GE + PP P Q P P P D
Sbjct: 2198 PYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQ----PSTPDPFLKPRCPSLD 2253
Query: 353 WVSAPDGPERHFRFNGAGGGIGAP-----------------RRRAAALSGPWGSPPPPPE 395
++ P+ P G GGG + ++ S P PP
Sbjct: 2254 NLAVPESP-------GVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGF 2306
Query: 396 QIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPP----TPPPTLQP 451
+ G L P F P + P PGL P PPP P P P
Sbjct: 2307 VDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHP 2366
Query: 452 PALQP---TPLPVAPPLTPGLGHKESALAPTAAPALPP-ALAADQAPAPSPAPAPTVAEP 507
+P T PPLTP + P + ALPP +L +D +P +
Sbjct: 2367 DIFRPGSYTDPYAQPPLTP----RPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQ 2422
Query: 508 SP----PVSAPAPAAAPIKTR 524
SP P+SA A +P+ R
Sbjct: 2423 SPLTPRPLSAEAFCPSPVTPR 2443
Score = 52.4 bits (124), Expect = 1e-06
Identities = 136/591 (23%), Positives = 183/591 (30%), Gaps = 113/591 (19%)
Query: 46 GLGVWFPGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLL 105
GL G PP VP SP L L L P P ++ ++ P
Sbjct: 2134 GLSTSADGFLKPPAGSVPGPD--SPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPT 2191
Query: 106 PGPSKWQKPAGTPVPRIRRLLEASHR-GQGDPPSLRPLKPPPPPRQLSVKDTV--PRAPS 162
P+ P+ T P +L AS R G G P P P Q S D PR PS
Sbjct: 2192 APPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPS 2251
Query: 163 ------QFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRA 216
P + K PL S + R + + GP N G +
Sbjct: 2252 LDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPS 2311
Query: 217 RGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLA-----PPAASSSLAAKASLGGG 271
G H G E+ P ++ L+ P L PP A + + S
Sbjct: 2312 SG---THLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPS---- 2364
Query: 272 GGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPAS 331
+F SY + Q PL P P E C+ PP
Sbjct: 2365 -HPDIFRPG---SYTDPYAQPPLTPRPQPPPPE---------------SCCALPP----- 2400
Query: 332 QARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPP 391
R+LP P++ P S +P P R A +P P+ PP
Sbjct: 2401 --RSLPSDPFSRVPASPQSQSSSQSPLTP----RPLSAEAFCPSPVTPRFQSPDPYSRPP 2454
Query: 392 PPPEQ------IHSAPGPRRPAPALLA--------------------------------- 412
P+ +H P P+ P A A
Sbjct: 2455 SRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQ 2514
Query: 413 PPTFIFPAPTNG-----EPMRPGPPGLQELPPLPPPTPPPTLQPP-----ALQPTPLPVA 462
PP F+ T PMR P P L PP P P L PP P P +
Sbjct: 2515 PPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGP-TLG 2573
Query: 463 PPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAP-AAAPI 521
P + P+ +P P + + ++ SP P+V P PAP + P
Sbjct: 2574 KPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPP------PAPDGSLPY 2627
Query: 522 KTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQT 572
+ + + R+D G G ATA +P + G SG SQT
Sbjct: 2628 LSHGASQRSGITSPVEKREDPGTGMG-SSLATAELPGTQ--DPGMSGLSQT 2675
Score = 50.8 bits (120), Expect = 4e-06
Identities = 148/630 (23%), Positives = 199/630 (31%), Gaps = 132/630 (20%)
Query: 11 GGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRG--LGVWFPGSATPPGLMVP---RE 65
GG K +AP + R S VEP+ +R P + P + P +
Sbjct: 2317 GGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTD 2376
Query: 66 PQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRL 125
P A P PLT P P PPPE A+ P P+ P+ Q + + P R
Sbjct: 2377 PYAQP---PLT---PRPQPPPPESCCALP-PRSLPSDPFSRVPASPQSQSSSQSPLTPRP 2429
Query: 126 LEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPAD 185
L A P + R P P R P P P KPP P P E
Sbjct: 2430 LSAEAFCPS-PVTPRFQSPDPYSRP-------PSRPQSRDPFAPLHKPPRPQPPEVAFKA 2481
Query: 186 RRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPH----AGEGEMAQPADSESGLSL 241
+ P AGP G+ + G PP+ G G G
Sbjct: 2482 GSLAHTSLGAGGFPAALPAGPA--GELHAKVPSGQPPNFVRSPGTGAFV-------GTPS 2532
Query: 242 LCKITFKS---RPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGA 298
+ TF PSL PP L + G G + V P G+
Sbjct: 2533 PMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGS 2592
Query: 299 ARPLGEVSRGAQEAEGGDGDGEGCSGPPSAP----------ASQARALPPP------PYT 342
PLG S E+ G PP AP ASQ + P P T
Sbjct: 2593 --PLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGT 2650
Query: 343 ---------TFPGSK-PKFDWVSAPDGPERHFRFN-----------------------GA 369
PG++ P +S + ++ R A
Sbjct: 2651 GMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAA 2710
Query: 370 GGGIGAPRRRAAALSGPWGSPPPPP--EQIHSAPGP---RRPAPALLAPPTFIFPAPTNG 424
G +G P G WG+ P P EQ+ P + +L+ P P+ +G
Sbjct: 2711 AGAVGPP--------GSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLP----PSKLSG 2758
Query: 425 EPMRPGP-PGLQELPPLPPPTPPPTLQPPA----------LQPTPLPVAPPLTPG---LG 470
+ PG P L PPP P ++ + Q P P + PL L
Sbjct: 2759 PILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLW 2818
Query: 471 HKESALAPTAA--------PALP-PALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPI 521
++ A A T+ P+ P P L +P + + P PV PA A I
Sbjct: 2819 QQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFI 2878
Query: 522 KTRTRRNKGSRAARGATRKDGLHGDGPRER 551
+ R KG G T G GP +R
Sbjct: 2879 ELRHNVQKG--LGPGGT---PFPGQGPPQR 2903
Score = 50.4 bits (119), Expect = 5e-06
Identities = 120/528 (22%), Positives = 162/528 (30%), Gaps = 143/528 (27%)
Query: 51 FPGSATPPGLMVPR---EPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPA---PAGTL 104
F G+ +P P+ EP P P P +PPP + P P P T
Sbjct: 2527 FVGTPSPMRFTFPQAVGEPSLKPPV-------PQPGLPPPHGINSHFGPGPTLGKPQSTN 2579
Query: 105 LPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQF 164
+ P+G+P L S G+ L PL+PP S
Sbjct: 2580 YTVATGNFHPSGSP-------LGPSSGSTGESYGLSPLRPP----------------SVL 2616
Query: 165 PPPLETWKPPPPLP------SERQ----PADRRITPALATPASPPTESQAGPRNQGQTAG 214
PPP P LP S+R P ++R P +S T G ++ G +
Sbjct: 2617 PPPA----PDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSG- 2671
Query: 215 RARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGG 274
+ E+ + + LL + + R +L +++ AA A +G G
Sbjct: 2672 ---------LSQTELEKQRQRQRLRELLIRQQIQ-RNTLRQEKETAAAAAGA-VGPPGSW 2720
Query: 275 GLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQAR 334
G +S A E L +G P + + G GP S P+
Sbjct: 2721 GAEPSSPAF---EQLSRGQTPFAGTQDKSSLVGLPPSKLSGP-----ILGPGSFPSDDRL 2772
Query: 335 ALPPPPYT----------------------TFPGSKP-------KFDWVSAPDGPERHFR 365
+ PPPP T +PGS P + A F
Sbjct: 2773 SRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFA 2832
Query: 366 FNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFI-------- 417
+ P AL P PGP P P P FI
Sbjct: 2833 MSARFPSTPGPELGRQALGSPLAGIST------RLPGPGEPVPGPAGPAQFIELRHNVQK 2886
Query: 418 ------FPAPTNGEPMRP------------GPPGLQ-----ELPPLPPPTPPPTLQPPAL 454
P P G P RP P GL+ LPP P PP +L
Sbjct: 2887 GLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSL 2946
Query: 455 QPTPLPVAPPLTPGLGHKESALAPTAAPAL----PPALAADQAPAPSP 498
PTP P L GL E P ++ L P AL A + P P
Sbjct: 2947 HPTPHTKGPTLPTGL---ELVNRPPSSTELGRPNPLALEAGKLPCEDP 2991
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/168 (30%), Positives = 60/168 (35%), Gaps = 18/168 (10%)
Query: 358 DGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFI 417
D P H R G +G+P AAA + GSP P SA G L PP
Sbjct: 2098 DRPALHLRIPPQPGALGSPPP-AAAPTIFIGSPTTPAGLSTSADG-------FLKPPAGS 2149
Query: 418 FPAPTN-GEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESAL 476
P P + GE PP ++P P P L P P APP P
Sbjct: 2150 VPGPDSPGELFLKLPP---QVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYP------ 2200
Query: 477 APTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTR 524
+PT APA PP L A P P P P+ +K R
Sbjct: 2201 SPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPR 2248
Score = 43.5 bits (101), Expect = 6e-04
Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 8/105 (7%)
Query: 383 LSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPP 442
L G G P +++ + P P+ P P L APP + P G PP + P P
Sbjct: 4263 LGGFPGPQTGPLQELGAGPRPQGP-PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPS 4321
Query: 443 PTPPPTLQ-------PPALQPTPLPVAPPLTPGLGHKESALAPTA 480
P P+ Q PP TP P P L P G A A A
Sbjct: 4322 QLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLA 4366
Score = 40.0 bits (92), Expect = 0.007
Identities = 47/150 (31%), Positives = 58/150 (38%), Gaps = 34/150 (22%)
Query: 376 PRRRAAALSGPWGSPPPPPEQIHSAPGPRR-PAPALLAPPTFIFPAPTNGEPMRPGPPG- 433
P + + L G G P Q+ PGP+ P L A P G P P PPG
Sbjct: 4246 PGTQTSPLQGLLGCQP----QLGGFPGPQTGPLQELGAGPR------PQGPPRLPAPPGA 4295
Query: 434 LQELPPLPP--PTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAAD 491
L P L P PTPPP+ +P+ LP S+ PT A LPP
Sbjct: 4296 LSTGPVLGPVHPTPPPSSPQEPKRPSQLP-----------SPSSQLPTEAQ-LPPT---- 4339
Query: 492 QAPAPSPAPAPTVAEPSPPVSAPAPAAAPI 521
P PT+ PP +PAAA +
Sbjct: 4340 -HPGTPKPQGPTL---EPPPGRVSPAAAQL 4365
Score = 38.5 bits (88), Expect = 0.020
Identities = 50/222 (22%), Positives = 71/222 (31%), Gaps = 48/222 (21%)
Query: 24 PDSRRTSLVEPEMTSQAM-----RLTRGLGVWFPGSATPPGLMVPREPQ--------ASP 70
P R S P T +M +L G ++ + P L + ++ Q +
Sbjct: 2767 PSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAA 2826
Query: 71 STLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPS--------------------K 110
+++ + P P PE P A T LPGP K
Sbjct: 2827 TSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQK 2886
Query: 111 WQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLET 170
P GTP P GQG P R P +L+ + A S PP +
Sbjct: 2887 GLGPGGTPFP-----------GQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPS 2935
Query: 171 WKPPPPLPSERQPADRRITPALATPAS----PPTESQAGPRN 208
P P L + P P L T PP+ ++ G N
Sbjct: 2936 APPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPN 2977
Score = 38.5 bits (88), Expect = 0.020
Identities = 49/174 (28%), Positives = 70/174 (40%), Gaps = 40/174 (22%)
Query: 295 PPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAP--ASQARALPPPPYTTFPGSKPKFD 352
P AR E +G E GG G P + P Q A+ P YT K + D
Sbjct: 4820 PESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPG-YTL----KSQLD 4874
Query: 353 WVS-------APDGPERH-FRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPR 404
+S AP+ P +H + +N + + R+ +A PPPE+ P P
Sbjct: 4875 ILSLLKQESPAPEPPTQHSYTYNVSNLDV----RQLSA---------PPPEEPSPPPSPL 4921
Query: 405 RPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTP 458
P+PA +PPT EP+ P PP+P P P + P + +P P
Sbjct: 4922 APSPA--SPPT---------EPLVELPTEPLAEPPVPSPLPLAS-SPESARPKP 4963
Score = 37.7 bits (86), Expect = 0.034
Identities = 37/137 (27%), Positives = 50/137 (36%), Gaps = 34/137 (24%)
Query: 419 PAPTNGEPMRPGPPGLQELPPL--------------------PPPTPPPTLQPP------ 452
P P E G G+Q P L PPP PT PP
Sbjct: 409 PGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLS 468
Query: 453 ----ALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAP-APSPAPAPTVAEP 507
L +PLP A L+ L + P +P PP ++ +P SP P + P
Sbjct: 469 PPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPP 528
Query: 508 SPPVS---APAPAAAPI 521
SP + +P P A+P+
Sbjct: 529 SPALETPLSPPPEASPL 545
Score = 36.6 bits (83), Expect = 0.075
Identities = 61/231 (26%), Positives = 74/231 (32%), Gaps = 56/231 (24%)
Query: 58 PGLMVPREPQAS--PSTLPLT----------LERPSPVMPPPEEAAAVSAPPP-APAGTL 104
P L P EP S P LPL+ L P P+ PP +APP +P G L
Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL 957
Query: 105 -----LPGPSKWQKPAGTPV--------------------PRIRRLLEASHRGQGDPPSL 139
G S + P P+ P I S G P +
Sbjct: 958 EYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILM 1017
Query: 140 RPLKPPPPPRQLSVKDTVPR--APSQFPPPLETWKPPPPLP--------SERQPADRRIT 189
PL PP L VP+ PSQ PP P PL S+ T
Sbjct: 1018 EPL--PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMET 1075
Query: 190 PALATPASPPTESQAG---PRNQGQTAGRARGGAP---PHAGEGEMAQPAD 234
++ P P E A P G + A AP +G GE P D
Sbjct: 1076 EKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLD 1126
Score = 35.0 bits (79), Expect = 0.22
Identities = 38/141 (26%), Positives = 49/141 (34%), Gaps = 24/141 (17%)
Query: 85 PPPEEAAAVSAPPPAPAGTL-----LPGPSKW--QKPAGTPVPRIRRLLEASHRGQGDPP 137
PP +E ++P G PGP Q+ P P+ L A P
Sbjct: 4241 PPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGP 4300
Query: 138 SLRPLKPPPPPRQLSVKDTVPRAPSQFP------------PPLETWKPPPPLPSERQPAD 185
L P+ P PPP P+ PSQ P PP P P P+ +P
Sbjct: 4301 VLGPVHPTPPPS----SPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPT-LEPPP 4355
Query: 186 RRITPALATPASPPTESQAGP 206
R++PA A A GP
Sbjct: 4356 GRVSPAAAQLADTLFSKGLGP 4376
Score = 35.0 bits (79), Expect = 0.22
Identities = 30/98 (30%), Positives = 35/98 (35%), Gaps = 20/98 (20%)
Query: 441 PPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAP 500
PPP P PP P P +PP P + E P A P P PSP P
Sbjct: 4909 PPPEEP---SPPPSPLAPSPASPPTEPLV---ELPTEPLAEP-----------PVPSPLP 4951
Query: 501 ---APTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAAR 535
+P A P P P R ++ KG R R
Sbjct: 4952 LASSPESARPKPRARPPEEGEDSRPPRLKKWKGVRWKR 4989
Score = 34.7 bits (78), Expect = 0.28
Identities = 26/87 (29%), Positives = 31/87 (35%), Gaps = 1/87 (1%)
Query: 435 QELPPLPPPTPPP-TLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQA 493
QE P PPT T L L PP P A +P + P P +
Sbjct: 4881 QESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEP 4940
Query: 494 PAPSPAPAPTVAEPSPPVSAPAPAAAP 520
A P P+P SP + P P A P
Sbjct: 4941 LAEPPVPSPLPLASSPESARPKPRARP 4967
Score = 33.9 bits (76), Expect = 0.48
Identities = 50/229 (21%), Positives = 74/229 (32%), Gaps = 50/229 (21%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW 111
PG+ + ++ P P PS+ P +RPS + P + + PP GT
Sbjct: 4293 PGALSTGPVLGPVHPTPPPSS-PQEPKRPSQLPSPSSQLPTEAQLPPTHPGT-------- 4343
Query: 112 QKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETW 171
KP G P+L P P + DT+ F L W
Sbjct: 4344 PKPQG--------------------PTLEPPPGRVSPAAAQLADTL------FSKGLGPW 4377
Query: 172 KPPPPLPSERQPADRRITP-------ALATPASPPTESQAGPRNQ-----GQTAGRARGG 219
PP L ++P + P P + + PR + Q+ R G
Sbjct: 4378 DPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANG 4437
Query: 220 AP---PHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAK 265
P P + SE+G LL K+ L+ S L A+
Sbjct: 4438 EPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAE 4486
Score = 31.2 bits (69), Expect = 3.1
Identities = 84/339 (24%), Positives = 116/339 (34%), Gaps = 89/339 (26%)
Query: 52 PGSATPPG---LMVPREPQASP----STLP------------LTLERPSPVMP------- 85
PGS P LM P PQ SP S +P L L PSP+ P
Sbjct: 1005 PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGV 1064
Query: 86 ---------PPEEAAAVSAPPPAPAGTL-LPGP-SKWQKPAGTPVPRIRRLLEASHRGQG 134
E+ + P P+ T LP P PA +P P L + S G+
Sbjct: 1065 SDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAP---ALDDFSGLGED 1121
Query: 135 -------DPPSLRPLKPPPPPRQLSVK---DTVPRAPSQFPP--PLETWKPPPPLPSERQ 182
D P +P +P P L+ + V P + P P+E + +
Sbjct: 1122 TAPLDGIDAPGSQP-EPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGS 1180
Query: 183 PADRRITPALATPASPPT------ESQAGPRNQGQTAGRARG-----GAPPHAGEGEMA- 230
P + + P +PPT ++ +QG + G G+P G G ++
Sbjct: 1181 PCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSM 1240
Query: 231 --------QPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGA 282
PA E L L ++ SL A ++ KA G G +S A
Sbjct: 1241 ELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAE----GEKGRRRSSPA 1296
Query: 283 ISYAEVLKQGPLP--PGAARPLGEVSRGAQEAEGGDGDG 319
S +KQG PG RP G A GG G G
Sbjct: 1297 RSR---IKQGRSSSFPGRRRPRG-------GAHGGRGRG 1325
Score = 31.2 bits (69), Expect = 3.1
Identities = 40/174 (22%), Positives = 60/174 (34%), Gaps = 11/174 (6%)
Query: 40 AMRLTRGLGVWFPGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPP--EEAAAVSAPP 97
+M++ V FP S G + P LE SP P ++ AV
Sbjct: 4808 SMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGY 4867
Query: 98 PAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTV 157
+ + K + PA P + S+ + P +P PPP
Sbjct: 4868 TLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS-------- 4919
Query: 158 PRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQ 211
P APS PP E P P P + P ++P S + +A P +G+
Sbjct: 4920 PLAPSPASPPTEPLVELPTEPLAEPPVPSPL-PLASSPESARPKPRARPPEEGE 4972
Score = 30.8 bits (68), Expect = 4.1
Identities = 27/89 (30%), Positives = 32/89 (35%), Gaps = 9/89 (10%)
Query: 145 PPPPRQLSVKDTVPRAPSQ---FPPPLETWKPPPPLPSERQPADRRITPALATP----AS 197
P PP Q S V + PPP E PPP P PA P + P A
Sbjct: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEP--SPPPSPLAPSPASPPTEPLVELPTEPLAE 4943
Query: 198 PPTESQAGPRNQGQTAGRARGGAPPHAGE 226
PP S + ++A PP GE
Sbjct: 4944 PPVPSPLPLASSPESARPKPRARPPEEGE 4972
Score = 30.4 bits (67), Expect = 5.3
Identities = 25/98 (25%), Positives = 31/98 (31%), Gaps = 20/98 (20%)
Query: 75 LTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQG 134
L+ P PPP A A PP LP + P +P+P
Sbjct: 4906 LSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPL-----------AS 4954
Query: 135 DPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWK 172
P S RP PP + PP L+ WK
Sbjct: 4955 SPESARPKPRARPPEE---------GEDSRPPRLKKWK 4983
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 93.2 bits (230), Expect = 7e-19
Identities = 115/460 (25%), Positives = 148/460 (32%), Gaps = 93/460 (20%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW 111
P A P G P+ P + P P PPP+ PPP P
Sbjct: 36 PQGAPPQGGNKPQGPPSPPG---------KPQGPPPQGGNQPQGPPPPPG---------- 76
Query: 112 QKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPS---QFPPPL 168
KP G P + ++ QG PP +P PPP K PR+P Q PPP
Sbjct: 77 -KPQGPPP-------QGGNKPQGPPPPGKPQGPPPQ----GDKSRSPRSPPGKPQGPPPQ 124
Query: 169 ETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGE 228
+P P P +P PP GP QG R+ +PP +G
Sbjct: 125 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRS-SRSPPGKPQGP 183
Query: 229 MAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEV 288
Q + G PP GG
Sbjct: 184 PPQGGNQPQG----------------PPPPPGKPQGPPPQGGNK---------------- 211
Query: 289 LKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSK 348
QGP PPG +P G +G +++ GPP +Q + PPPP G
Sbjct: 212 -PQGPPPPG--KPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKP-QGPP 267
Query: 349 PKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAP 408
P+ + P GP + G G+ R + + P G P PP Q + P P P
Sbjct: 268 PQGG--NKPQGPPPPGKPQGPPPQGGSKSRSSRS---PPGKPQGPPPQGGNQPQGPPPPP 322
Query: 409 ALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPP----------TPPPTLQPPALQPTP 458
P P +P P PPG P PPP +PP Q P Q
Sbjct: 323 GKPQGP----PPQGGNKPQGPPPPGK---PQGPPPQGGSKSRSARSPPGKPQGPPQQEGN 375
Query: 459 LPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSP 498
P PP G ++ P P PP P+ P
Sbjct: 376 NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 77.0 bits (188), Expect = 5e-14
Identities = 116/475 (24%), Positives = 146/475 (30%), Gaps = 131/475 (27%)
Query: 78 ERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPP 137
E PS + P+ A PP PS KP G P + ++ QG PP
Sbjct: 27 ESPSLIAGNPQGA------PPQGGNKPQGPPSPPGKPQGPPP-------QGGNQPQGPPP 73
Query: 138 SLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPAS 197
P KP PP Q K P+ P PPP + PPP R +P S
Sbjct: 74 P--PGKPQGPPPQGGNK---PQGP---PPPGKPQGPPPQGDKSR------------SPRS 113
Query: 198 PPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPA 257
PP + Q GP QG G G PP G +P PP
Sbjct: 114 PPGKPQ-GPPPQG---GNQPQGPPPPPG------------------------KPQGPPPQ 145
Query: 258 ASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDG 317
+ QGP PPG +P G +G ++
Sbjct: 146 GGNK----------------------------PQGPPPPG--KPQGPPPQGDNKSRSSRS 175
Query: 318 DGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPR 377
GPP +Q + PPPP P GP GG
Sbjct: 176 PPGKPQGPPPQGGNQPQGPPPPP--------------GKPQGPPPQ-------GG----- 209
Query: 378 RRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQEL 437
+ P G PPP Q G + A P P P G + PP
Sbjct: 210 ------NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP----- 258
Query: 438 PPLPPPTPPPT--LQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPA 495
PP P PPP +P P P PP G S+ +P P PP +Q
Sbjct: 259 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG-SKSRSSRSPPGKPQGPPPQGGNQPQG 317
Query: 496 PSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRE 550
P P P P + P P K + +G +R A G P++
Sbjct: 318 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQ 372
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 88.2 bits (217), Expect = 2e-17
Identities = 121/457 (26%), Positives = 167/457 (36%), Gaps = 52/457 (11%)
Query: 80 PSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLL--EASHRGQGDPP 137
P+PV P + + PAP G LP + P + +++ +A G P
Sbjct: 1269 PTPVSVLPSSTPSTT---PAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVP 1325
Query: 138 SLRPLKPPPP---PRQLSVKDTVPRAPSQFPPP-LETWKPPPPLPSERQPADRRI-TPAL 192
L P PP P L+ + T+ P + P P L T + P P P+ +P + + +P+
Sbjct: 1326 PLAPAPRPPSSGLPAVLNPRPTL--TPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSP 1383
Query: 193 ATPASPPTESQ---AGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKS 249
AS P + + P + + P +A P S + L +
Sbjct: 1384 EVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISV 1443
Query: 250 RPSL-APPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRG 308
+L AP +A ++ A L G S A V+ P PP A S
Sbjct: 1444 PTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSAS 1503
Query: 309 AQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSK--PKFDWVSAPDGPERHFRF 366
A G +AP+ + P P P S P + AP
Sbjct: 1504 ALTL-----------GLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAP--------- 1543
Query: 367 NGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGE- 425
A + P A+AL+ P+ S P P S P A LA P AP
Sbjct: 1544 --ACSPVLVP---ASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAIL 1598
Query: 426 PMRPGPPGLQELPPLPPPTPPPTLQPP-ALQPTPLPV-APPLTPGLGHKESALAPTAAPA 483
P PP L PLP P P P A TP+PV AP TPG ++ P P
Sbjct: 1599 APSPAPP----LAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPV 1654
Query: 484 LPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAP 520
L P+ PAP P+P P+ A S A APA AP
Sbjct: 1655 LAPSSTQTMLPAPVPSPLPSPA--STQTLALAPALAP 1689
Score = 82.4 bits (202), Expect = 1e-15
Identities = 135/537 (25%), Positives = 181/537 (33%), Gaps = 54/537 (10%)
Query: 19 PSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQASPSTLPLTLE 78
P+ R P S +++ P T LT PG P L R P +P TL
Sbjct: 1329 PAPRPPSSGLPAVLNPRPT-----LT-------PGRLPTPTLGTARAPMPTP-----TLV 1371
Query: 79 RPSPVM---PPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASH----- 130
RP + P PE +A+ P + L PS PA +P+P AS
Sbjct: 1372 RPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTV 1431
Query: 131 ---RGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPS-ERQPADR 186
P S+ P P L++ + P S P L T PP P P
Sbjct: 1432 SVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPP 1491
Query: 187 RITPALATPASPPTE---SQAGPRNQGQTAGRARGGAPPHA---GEGEMAQPADSESGLS 240
+ P+ A+P++ + A + QT G AP + G PA S +
Sbjct: 1492 SLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVP 1551
Query: 241 LLCKIT-FKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAA 299
+ F S P+ AP A +SL A AS A A A +L P PP A
Sbjct: 1552 ASALASPFPSAPNPAP--AQASLLAPASSASQALATPLAPMAAPQTA-ILAPSPAPPLAP 1608
Query: 300 RPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDG 359
P+ S GA P S P + + P P T P P P
Sbjct: 1609 LPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPT-PVLAPSSTQTMLPAP 1667
Query: 360 PERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPAL---LAPPTF 416
+ + A AL+ G P P+ P P L P +
Sbjct: 1668 VPSPLPSPASTQTLAL----APALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASS 1723
Query: 417 IFPAPTNGEPMRPGPP-------GLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGL 469
+ P P + PGPP L PPL P +P L P + L
Sbjct: 1724 LVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPA 1783
Query: 470 GHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTR 526
+ L+P P L PA A A AP+ +P S VSA A P+ +R
Sbjct: 1784 SVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSR 1840
Score = 76.6 bits (187), Expect = 7e-14
Identities = 129/508 (25%), Positives = 179/508 (35%), Gaps = 73/508 (14%)
Query: 60 LMVPREPQASPSTLPLTLERPSPVMPPPEE---AAAVSAPPPAPAGTLL----PGPSKWQ 112
L V P P P+ ++ + P P++ V P AP G + PGP
Sbjct: 975 LEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSA 1034
Query: 113 KPAGTPVPRI---RRLLEASHRGQGDPPSLRP----LKPPPPPRQLSVKDTVPR------ 159
+P PVP++ ++ AS G P+ RP L PP P S+ +P
Sbjct: 1035 QPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLS 1094
Query: 160 APSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGG 219
S+ P P + KP PP P PA + +L P + P P T+
Sbjct: 1095 GTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTT--- 1151
Query: 220 APPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAA 279
A A PA + + L+ ++R + LA+ A GG
Sbjct: 1152 ----ATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPL 1207
Query: 280 SGAISYAEVLKQG----PLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARA 335
+ I ++ G L G RPL R G S P QA A
Sbjct: 1208 TFQIQGNKLTLTGAQVRQLAVGQPRPL---QRNVVHLVSAGGQHHLISQPAHVALIQAVA 1264
Query: 336 LP--PPPYTTFPGSKPKFDWVSAPDGPERHFRFNGA------GGGIGAPRRRAAALSGPW 387
P P + P S P AP G N G+ R A G
Sbjct: 1265 PTPGPTPVSVLPSSTP--STTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGL- 1321
Query: 388 GSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPP 447
+P PP AP PR P+ L P + P PT + PG L P P P
Sbjct: 1322 -TPVPP-----LAPAPRPPSSGL---PAVLNPRPT----LTPGRLPTPTLGTARAPMPTP 1368
Query: 448 TLQPPALQ--PTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAP----- 500
TL P L+ +P P PG + +P P+ P A+ P P+ +P
Sbjct: 1369 TLVRPLLKLVHSPSPEVSASAPGAA-PLTISSPLHVPSSLPGPASSPMPIPNSSPLASPV 1427
Query: 501 APTVAEP-------SPPVSAPAPAAAPI 521
+ TV+ P S P + PAPA+AP+
Sbjct: 1428 SSTVSVPLSSSLPISVPTTLPAPASAPL 1455
Score = 58.9 bits (141), Expect = 1e-08
Identities = 144/564 (25%), Positives = 188/564 (33%), Gaps = 114/564 (20%)
Query: 57 PPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPP--PAPAGTLL-----PGPS 109
P LMV P A P +P + P PV+ PP + + S P P+P G L P P+
Sbjct: 1046 PASLMVSASP-AGPPLIPAS-RPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPT 1103
Query: 110 KWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPP----PPRQLSVKDTVPR------ 159
KP TP P RL A G L+PL PP PP + T
Sbjct: 1104 LSLKP--TP-PAPVRLSPAPPPGSSS--LLKPLTVPPGYTFPPAAATTTSTTTATATTTA 1158
Query: 160 --APSQFP------PPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQ 211
AP+ P P ++ P + S Q A P S P Q
Sbjct: 1159 VPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTL 1218
Query: 212 TAGRAR--------------------GGA------PPHAGEGEMAQPADSESGLSLLCKI 245
T + R GG P H + P + +S+L
Sbjct: 1219 TGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSS 1278
Query: 246 TFKSRPSLAPPAASSSLAAK----ASLGGGGGGGLF---AASGAISYAEVLKQGPLPPGA 298
T + P AP S LAA + G + A ++ L P PP +
Sbjct: 1279 TPSTTP--APTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSS 1336
Query: 299 ARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPD 358
P R P+ ARA P P +P V +P
Sbjct: 1337 GLPAVLNPRPTLTP----------GRLPTPTLGTARAPMPTPTLV----RPLLKLVHSPS 1382
Query: 359 GPERHFRFNGAGG-GIGAPRRRAAALSGPWGSPPPPPEQ------IHSAPGPRRPAPALL 411
PE GA I +P ++L GP SP P P + S + +
Sbjct: 1383 -PEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPI 1441
Query: 412 APPTFIFPAPTNGEPMRP----------GPPGLQELPPLPPPTPPPTLQPPALQPTPL-P 460
+ PT + PAP + P GP L + P P P PP+L P+ P
Sbjct: 1442 SVPTTL-PAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASP 1500
Query: 461 VAPPLTPGLGHKESA-----------LAPTAAPALPPALAADQAPAPSPAPAPTVAEPSP 509
A LT GL S LAPT++ P L + APA SP P A SP
Sbjct: 1501 SASALTLGLATAPSLSSSQTPGHPLLLAPTSSHV--PGLNSTVAPACSPVLVPASALASP 1558
Query: 510 PVSAPAPAAAPIKTRTRRNKGSRA 533
SAP PA A + S+A
Sbjct: 1559 FPSAPNPAPAQASLLAPASSASQA 1582
Score = 53.5 bits (127), Expect = 6e-07
Identities = 161/724 (22%), Positives = 232/724 (32%), Gaps = 211/724 (29%)
Query: 5 QSEPSAGGGSRKVQPSDRAPDSRRTSLVE---------------PEMTSQAMRLTRGLGV 49
+S GGG+ + +AP+ T + E P +++ R T
Sbjct: 2369 ESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTT--- 2425
Query: 50 WFPGSATPPGLMVPRE-----------PQASPSTLPLTLERPSPVMPP-PEEAAAV---- 93
P +P VPR P A P+ +P+ + P P+ P P V
Sbjct: 2426 --PPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILP 2483
Query: 94 SAPPPA-------PAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPS-------- 138
S PPP+ PA T P P+ PA TP P L+ S PPS
Sbjct: 2484 SPPPPSQIPPCSSPACT--PPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVT 2541
Query: 139 -----LRP--------LKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPAD 185
LRP L P SV + + S PP K P+ E P
Sbjct: 2542 NLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPP-----KDLLPVAVEILPVS 2596
Query: 186 RRITPALATPASPPTESQAG--PRNQGQTAGRARGGA----------------------- 220
+ TP++P +AG P Q Q A + G
Sbjct: 2597 EKNLSL--TPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLEL 2654
Query: 221 PPHAGEGE-MAQPADSESGLSLLCKI-TFKSRPS---------LAPPAASSSL------- 262
PP A E + +P +++ L + T S P +A P+ SSS
Sbjct: 2655 PPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGP 2714
Query: 263 ----------AAKASLGGGGGGGLFAASG-------------AISYAEVLKQGPLPPGAA 299
+A + G G G G + E++++ GAA
Sbjct: 2715 SPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAA 2774
Query: 300 RPLGEVSRGAQEAEGGDGDGE--GCSGPPSAP-------ASQARALPPPPYTTFPGSKPK 350
L G E G SGP S+P A+ + +LP PP F
Sbjct: 2775 STLVP---GVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIA---- 2827
Query: 351 FDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPA- 409
RH GGG +P AL PP ++ P + +PA
Sbjct: 2828 ----------RRHIELGVTGGG--SPENGDGALLA---ITPPAVKRRRGRPPKKNRSPAD 2872
Query: 410 ----LLAPPTFIFPAPTNGEPMRPGP---------------PGLQELPPLPPPTPPPTL- 449
+ P+ TNG PGP PG Q L P P P P L
Sbjct: 2873 AGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLS 2932
Query: 450 --------QPPALQPTPLPVAPPLTPGLGHKESALAPTAAPA----LPPALAADQAPAPS 497
+PP + P+P + G G+ ES P P+ LPP L A +
Sbjct: 2933 PVEKRRRGRPPKARDLPIP-GTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVAN 2991
Query: 498 PAPAPTVA-------EPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRE 550
T++ PP + P+P + + R + + G R+ G G E
Sbjct: 2992 TVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESE 3051
Query: 551 RATA 554
+++
Sbjct: 3052 GSSS 3055
Score = 42.7 bits (99), Expect = 0.001
Identities = 78/304 (25%), Positives = 104/304 (34%), Gaps = 74/304 (24%)
Query: 65 EPQASPSTLPL---TLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPR 121
EPQ P PL + RP+P++ P E+ PP +PG AG
Sbjct: 2909 EPQLIPGPQPLGPQPVHRPNPLLSPVEKRRR--GRPPKARDLPIPGTIS---SAGDG--- 2960
Query: 122 IRRLLEASHRGQGDPPSLRPLKPPPPPR---QLSVKDTVPRAPSQFPPPLETW-----KP 173
+ R Q PP PL P PP +V +TV PP P
Sbjct: 2961 -----NSESRTQ-PPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNP 3014
Query: 174 PPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAG------------------- 214
P P PS+ DR T L S + P+ QG++ G
Sbjct: 3015 PSPRPSQLPVLDRDSTSVLE---SCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLARLRL 3071
Query: 215 -------RARGGAPPHAGEGEMAQPADSESG--------LSLLCKI-TFKSRP-SLAPPA 257
R GG+ A + ADS G +SL K+ + + RP SL PP
Sbjct: 3072 EAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSLTPKLRSTRLRPGSLVPPL 3131
Query: 258 ASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDG 317
+ L K + GG A G + PP P G V EA G +
Sbjct: 3132 ETEKLPRKRAGAPVGGSPGLAKRGRLQ----------PPSPLGPEGSVEESEAEASGEEE 3181
Query: 318 DGEG 321
+G+G
Sbjct: 3182 EGDG 3185
Score = 41.2 bits (95), Expect = 0.003
Identities = 43/149 (28%), Positives = 55/149 (36%), Gaps = 32/149 (21%)
Query: 420 APTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPP-----------LTPG 468
AP P+RP PPG EL P P P P + P +L + P PP L P
Sbjct: 1017 APLGPVPVRP-PPG-PELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPP 1074
Query: 469 LGHKESA-----------LAPTAAPALPPALAADQAPAP---SPAPAPTVAEPSPPVSAP 514
L + L+ T+ P P PAP SPAP P + P++ P
Sbjct: 1075 LQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVP 1134
Query: 515 -----APAAAPIKTRTRRNKGSRAARGAT 538
PAAA + T + A T
Sbjct: 1135 PGYTFPPAAATTTSTTTATATTTAVPAPT 1163
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 86.7 bits (213), Expect = 6e-17
Identities = 128/543 (23%), Positives = 189/543 (34%), Gaps = 89/543 (16%)
Query: 19 PSDRAPD--SRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQASPSTLPLT 76
PS AP S V+ ++ ++ G F TPP + S S P
Sbjct: 650 PSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFK-PPTPPVMQ-------SQSVKPQI 701
Query: 77 LERPSPVMPPPEEAAAVSAPPPAPAGT---LLPGPSKWQKPAGTPVPRIRRLLEASHRGQ 133
L P+ V+PPP PPP P L P P P + P ++ + H Q
Sbjct: 702 LVPPNGVVPPPPPPP----PPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQ 757
Query: 134 GDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALA 193
PP+ PPPPP P PL PP PL + P + +
Sbjct: 758 VAPPT-----PPPPP--------------PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVV 798
Query: 194 TPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSL 253
T A+PPT + P + Q A A PP + P +L + +F ++P
Sbjct: 799 TQAAPPTPTPPVPPAKKQPAFPA-SYIPPSPPTPPVPVPPP-----TLPKQQSFCAKPPP 852
Query: 254 APPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAE 313
+P + S+ + + F E P+P A + + +
Sbjct: 853 SPLSPVPSVVKQIA-------SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ 905
Query: 314 GGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGI 373
PP P S + PPPP + P P ++P P++
Sbjct: 906 PSSIPVPSPDFPPPPPES-SLVFPPPPPSPVPAPPPPPPPTASPT-PDKS---------- 953
Query: 374 GAPRRRAAALSGPWGSPPPPPEQ----IHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRP 429
G+P ++ + S P G PPP Q I S+ G P P + + + P
Sbjct: 954 GSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFT---PPAES 1010
Query: 430 GPPGLQELPPLPPPTPPPTLQ------PPALQPTPLPVAPPLTPGLGHKESAL---APTA 480
G P + LPP P P L P LQ + P+ G G K+S + +P +
Sbjct: 1011 GSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG-KDSVVEFPSPPS 1069
Query: 481 APALPPALAADQAPAP----------SPAPAPTVAEPSPPV-SAPAPAAAPIKTRTRRNK 529
PP + P P + +P V P P S + AP TR +RN
Sbjct: 1070 DSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRND 1129
Query: 530 GSR 532
+R
Sbjct: 1130 STR 1132
Score = 80.5 bits (197), Expect = 5e-15
Identities = 106/444 (23%), Positives = 146/444 (32%), Gaps = 79/444 (17%)
Query: 140 RPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPP 199
RP PP K P SQ PPL PPPP P P P PP
Sbjct: 600 RPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP-----------PPPPP 648
Query: 200 TESQAGPRNQGQTAGRARGGAPPHAGEGEMA--QPADSESGLSLLCKITFKSRPSLAPPA 257
SQ+ P +AG A AP + Q A SG +P P
Sbjct: 649 LPSQSAP-----SAGSA---APMFVKYSTITRLQNASQHSGALF--------KPPTPPVM 692
Query: 258 ASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDG 317
S S+ + + G V+ P PP P G + A
Sbjct: 693 QSQSVKPQILVPPNG---------------VVPPPPPPPPPPTP-GSAMAQLKPAPCAPS 736
Query: 318 DGEGCSGPPSAPASQARAL------PPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGG 371
+ + PP Q + + PPP P P P P + A
Sbjct: 737 LPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP-------PQAPPKPLVTIPAPT 789
Query: 372 GIGAPRRRAAALSGPWGSPPPPPEQIH----------SAPGPRRPAPALLAPPTFIFPAP 421
+ P +PP PP + S P P P P P F A
Sbjct: 790 STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAK 849
Query: 422 TNGEPMRPGPPGLQEL-PPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHK---ESALA 477
P+ P P ++++ PPP PP ++ L+P P VAP P + K + +
Sbjct: 850 PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSI 909
Query: 478 PTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGA 537
P +P PP P P P+P A P PP P + P K+ + K S+ +
Sbjct: 910 PVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPP--PPTASPTPDKSGSPGKKTSKTSSPG 967
Query: 538 TRKDGLHGDGPRERATATVPDSSG 561
+K P + +++ SSG
Sbjct: 968 GKK-----PPPTPQRNSSIKSSSG 986
Score = 70.5 bits (171), Expect = 5e-12
Identities = 129/500 (25%), Positives = 172/500 (34%), Gaps = 103/500 (20%)
Query: 8 PSAGGGSRKVQPSDRAPDSRRTSLVEPEMT-SQAMRLTRGLGVWFPGSATPPGLMVPREP 66
P+ G +++P+ AP + S P + Q +T+ V P PP + P P
Sbjct: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQ---VAPPTPPPPPPIPAPLPP 775
Query: 67 QASPSTLPLTLERPSP---VMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIR 123
QA P L +T+ P+ V P +AA + PP P P P P P +
Sbjct: 776 QAPPKPL-VTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPV- 833
Query: 124 RLLEASHRGQGDPPSLRP-----LKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLP 178
PP+L KPPP P V V + SQFPPP P P
Sbjct: 834 ---------PVPPPTLPKQQSFCAKPPPSPLS-PVPSVVKQIASQFPPP--------PTP 875
Query: 179 SERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESG 238
+ + PA P SPP +A P+ Q + PP E + P S
Sbjct: 876 PAMESQPLKPVPANVAPQSPPA-VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP 934
Query: 239 LSLLCKITFKSRPSLAPPAA------SSSLAAKASLGGGGGGGLFAASGAISYAEVLKQG 292
+ + P PP A S S K S GG + + + G
Sbjct: 935 V--------PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG 986
Query: 293 PLPPGAARPLGE--VSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPK 350
P RP + VS+ AE SG PS LPPP PG K
Sbjct: 987 AEHPEPKRPSVDSLVSKFTPPAE---------SGSPS-----KETLPPPAAPPKPG-KLN 1031
Query: 351 FDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSG------------PWGS--PPPPPEQ 396
V+ P ++ G +A LSG P S PPPPPE
Sbjct: 1032 LSGVNLPGVLQQ-----------GCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPET 1080
Query: 397 IHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPAL-- 454
P P PA+ + T A N +P + +++ PPPT P L
Sbjct: 1081 --ELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKK---APPPTRPKRNDSTRLTQ 1135
Query: 455 -----QPTPLPVAP--PLTP 467
QPT V P P +P
Sbjct: 1136 AEISEQPTMATVVPQVPTSP 1155
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 84.7 bits (208), Expect = 2e-16
Identities = 153/586 (26%), Positives = 181/586 (30%), Gaps = 95/586 (16%)
Query: 51 FPGSATPPGLMVPREPQASPSTL--PLTLERPSPVMPPPEEAAAVSAPPPAPAGTL---- 104
+PG A PPG P P T P + P PP E A + PP P G +
Sbjct: 172 YPGPAGPPG------PPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSG 225
Query: 105 ------------------LPGPSKWQKPAGTP-VPRIRRLLEASHRGQGDPPSLRPLKPP 145
LPGP + PAG P P ++ HRG +
Sbjct: 226 PAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMK-----GHRGFDGRNGEKGETGA 280
Query: 146 PPPRQLSVKDTVPRAPSQFPP---PLETWKPPPP-----------LPSERQPADRRITPA 191
P + + AP P P E +P P S+ QP
Sbjct: 281 PGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGT 340
Query: 192 LATPASPPTESQAGPR----NQGQTAGRARGGAPPHAG-EGEMAQPA--DSESGLSLLCK 244
P SP + + GP + G R G HAG +G P S G +
Sbjct: 341 AGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGP 400
Query: 245 ITFKSRPSL----APPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLP--PGA 298
P L PP + + A GG G G A G + +P PGA
Sbjct: 401 AGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGA 460
Query: 299 ARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPD 358
GE + E G G +G AP + A P PG K AP
Sbjct: 461 K---GEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP----NGIPGEKGPAGERGAPG 513
Query: 359 --GPERHFRFNGAGGGIGAPRRRAAALS----GPWGSPPPPPEQIHSA-PGPRRPAPALL 411
GP G G G P R S G G P PP Q S PGP P+
Sbjct: 514 PAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRG 573
Query: 412 APPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGH 471
P FP P G PG G + P P P PP P PP G G
Sbjct: 574 QPGVMGFPGP-KGNDGAPGKNGERGGPGGPGPQ-----GPPGKNGETGPQGPPGPTGPGG 627
Query: 472 KESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGS 531
+ P L P + P EP P A AP A KG
Sbjct: 628 DKGDTGPPGPQGLQGLPGTGGPPGENGKP----GEPGPKGDAGAPGAP-------GGKGD 676
Query: 532 RAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANT 577
A G GL G P R A P GG G GAA T
Sbjct: 677 AGAPGERGPPGLAG-APGLRGGAGPPGPEGGKGAAGPPGPPGAAGT 721
Score = 82.0 bits (201), Expect = 2e-15
Identities = 140/550 (25%), Positives = 174/550 (31%), Gaps = 92/550 (16%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAP--------PPAPAGT 103
PG PG P P+ +P ER P +P A PP P GT
Sbjct: 290 PGENGAPG---PMGPRGAPG------ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGT 340
Query: 104 L----LPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQL--SVKDTV 157
PG PAG+P RG+ P + PP P + S
Sbjct: 341 AGFPGSPGAKGEVGPAGSPGSNGA----PGQRGEPGPQGHAGAQGPPGPPGINGSPGGKG 396
Query: 158 PRAPSQFP--PPLETWKPPPPLPSERQPADRRITPALATPASPPTESQA----GPRNQGQ 211
P+ P P L + PP PA P L A P ++ A GPR +
Sbjct: 397 EMGPAGIPGAPGLMGARGPPG------PAGANGAPGLRGGAGEPGKNGAKGEPGPRGERG 450
Query: 212 TAGRARGGAPPHAGE-GEMAQPAD-SESGLSLLCKITFKSRPSLAPPAASSSLAAKASLG 269
AG G P GE G+ P + +GL P A+ A G
Sbjct: 451 EAGIP--GVPGAKGEDGKDGSPGEPGANGL----------------PGAAGERGAPGFRG 492
Query: 270 GGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAP 329
G G+ G ++G PG A P G ++ G G G P P
Sbjct: 493 PAGPNGIPGEKGPAG-----ERGA--PGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGP 545
Query: 330 ASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGS 389
S + P PP + +P S P G F G G GAP + GP G
Sbjct: 546 GSDGK--PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGER-GGPGGP 602
Query: 390 PPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPT--NGEPMRPGPPGLQELPPLPPPTPPP 447
P P + GP+ P P PT G+ GPPG Q L LP PP
Sbjct: 603 GPQGPPGKNGETGPQGP------------PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650
Query: 448 TLQPPALQPTPL-PVAPPLTPGLGHKESALAPTAAPAL--PPALAADQAPAPSPAPAPTV 504
+P P P PG A P L P L P
Sbjct: 651 GENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAA 710
Query: 505 AEPSPPVSAPAPAAAPIKTR-----TRRNKGSRAARGATRKDGLHG-DGPRERATATVPD 558
P PP +A P + + KG + G DG+ G DGPR P
Sbjct: 711 GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770
Query: 559 SSGGGGGGSG 568
G G G
Sbjct: 771 GPAGQPGDKG 780
Score = 76.3 bits (186), Expect = 9e-14
Identities = 154/602 (25%), Positives = 186/602 (30%), Gaps = 117/602 (19%)
Query: 52 PGSATP---PGLMVPREPQASPSTLPLTLER-----PSPVMPPPEEAAAVSAPPPAPAGT 103
PG + P PG+M P+ + ER P P PP + PP P G
Sbjct: 566 PGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG- 624
Query: 104 LLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQ 163
PG K G P P+ + L G G PP P P+ + P
Sbjct: 625 --PGGDKGD--TGPPGPQGLQGLP----GTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676
Query: 164 FPPPLETWKP----PPPLPSERQPADRRITPALATPASPPTES----------------Q 203
P E P P L P A P PP +
Sbjct: 677 AGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS 736
Query: 204 AGPR-NQGQTAGRARGGAP----------PHAGEGEMAQPADS-ESGLSLLCKITFK--- 248
GP+ ++G+ G G P P G QP D E G L I
Sbjct: 737 PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGS 796
Query: 249 --SRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPL----PPGAARPL 302
R PP + A G GG G A G E + GP PPG + P
Sbjct: 797 PGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPG-----EKGEGGPPGVAGPPGGSGPA 851
Query: 303 GEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPER 362
G + E G G G +G P A R LP PP + P DGP
Sbjct: 852 GPPGPQGVKGERGSPGGPGAAGFPGA-----RGLPGPPGSNGNPGPPGPSGSPGKDGPP- 905
Query: 363 HFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQ-------IHSAPGPRRPA-------- 407
G G GAP + +SGP G P E+ APGP A
Sbjct: 906 -----GPAGNTGAP--GSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGL 958
Query: 408 ---PALLAPPTFIFPAPTNGEPMRPGPPGL--QELPPLPPPTP--PPTLQPPALQPTPLP 460
P + P P GE +PG GL + PP P P T P P
Sbjct: 959 AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS 1018
Query: 461 VAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAE-----PSPPVSAPA 515
P G + +P P A P P PA + P+ P AP
Sbjct: 1019 DGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGP-VGPAGKSGDRGESGPAGPAGAPG 1077
Query: 516 PA---AAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQT 572
PA AP R +KG RGA G G P + G G A Q
Sbjct: 1078 PAGSRGAPGPQGPRGDKGETGERGAAGIKGHRG----------FPGNPGAPGSPGPAGQQ 1127
Query: 573 GA 574
GA
Sbjct: 1128 GA 1129
Score = 70.9 bits (172), Expect = 4e-12
Identities = 145/542 (26%), Positives = 176/542 (32%), Gaps = 101/542 (18%)
Query: 77 LERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDP 136
L+ P+P +P E A PP AP T P Q P G P P G P
Sbjct: 72 LDCPNPEIPFGECCAVCPQPPTAP--TRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQP 129
Query: 137 PSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETW-----------------KPPPPLPS 179
S P P PP + ++ P P + P +++ PP P
Sbjct: 130 GS--PGSPGPP----GICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPG 183
Query: 180 ERQPADRRITPALATPASPPTE-SQAGPRNQGQTAGRARGGAPPHAGEGEMAQPA-DSES 237
+ +P PP E QAGP G A G + P +GE +P E
Sbjct: 184 PPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPG-AIGPSGPAGKDGESGRPGRPGER 242
Query: 238 GLSLLCKITFKSRPSLAPPAASSSL-AAKASLGGGGGGGLFAASGAISY-------AEVL 289
GL P + PA K G G G +GA E
Sbjct: 243 GL--------PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENG 294
Query: 290 KQGPLPPGAARPLGEVSR----GAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFP 345
GP+ P A GE R GA A G DG G G P P PP FP
Sbjct: 295 APGPMGPRGAP--GERGRPGLPGAAGARGNDG-ARGSDGQPGPPG-------PPGTAGFP 344
Query: 346 GSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRR 405
GS GP NGA G G P + A G G PP P I+ +PG +
Sbjct: 345 GS----PGAKGEVGPAGSPGSNGAPGQRGEPGPQGHA--GAQG--PPGPPGINGSPGGKG 396
Query: 406 PAPALLAPPTFIFPAP-TNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTP------ 458
P I AP G PGP G P L P +P P
Sbjct: 397 E-----MGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGE 451
Query: 459 --LPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPA----PSPAPAPTVAEPSPPVS 512
+P P G K+ + A LP A AP P P P+
Sbjct: 452 AGIPGVPG-AKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERG 510
Query: 513 APAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQT 572
AP PA G R A G +DG+ G GP R +P S GG G
Sbjct: 511 APGPA------------GPRGAAGEPGRDGVPG-GPGMRG---MPGSPGGPGSDGKPGPP 554
Query: 573 GA 574
G+
Sbjct: 555 GS 556
Score = 68.6 bits (166), Expect = 2e-11
Identities = 138/560 (24%), Positives = 177/560 (31%), Gaps = 74/560 (13%)
Query: 53 GSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQ 112
G+A PPG P +P + ER P P+ P A GP
Sbjct: 708 GAAGPPG---PPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPT 764
Query: 113 KPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPP---PPPRQLSVKDTVPRAPSQFP-PPL 168
P G P P + +G+G P L + P P R +T P P+ FP P
Sbjct: 765 GPIGPPGPAG----QPGDKGEGGAPGLPGIAGPRGSPGERG----ETGPPGPAGFPGAPG 816
Query: 169 ETWKP-------PPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAP 221
+ +P P E P P + PA PP GP QG R G P
Sbjct: 817 QNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP-----GP--QGVKGERGSPGGP 869
Query: 222 PHAG-EGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAAS 280
AG G P S + S PP + + A S G G G
Sbjct: 870 GAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQP 929
Query: 281 GAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPP 340
G QGP PGA PLG G G +GPP P R P P
Sbjct: 930 GEKGSPGA--QGP--PGAPGPLGIA---------GITGARGLAGPPGMPGP--RGSPGPQ 974
Query: 341 YTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRR----AAALSGPWGSPPPPPEQ 396
KP + +S GP G G G P R + L G GSP ++
Sbjct: 975 GVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDR 1034
Query: 397 IHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQP 456
+ AP PP + PA +G+ GP G P P +
Sbjct: 1035 GENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAG-----------PAGAPGPAGSRG 1083
Query: 457 TPLPVAPPLTPG----------LGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAE 506
P P P G GH+ P A + PA +P PA
Sbjct: 1084 APGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVG 1143
Query: 507 PSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGG 566
PS P + P +G+R RG+ G P + P + G GG
Sbjct: 1144 PSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPG----HPGQPGPPGPPGAPGPCCGG 1199
Query: 567 SGASQTGAANTRAARHWLPF 586
GA+ A + P+
Sbjct: 1200 VGAAAIAGIGGEKAGGFAPY 1219
Score = 57.0 bits (136), Expect = 5e-08
Identities = 109/442 (24%), Positives = 135/442 (30%), Gaps = 104/442 (23%)
Query: 198 PPTESQAGPRNQGQTAGRARGGAPPHAGE----GEMAQPADSES-GLSLLCKITFKSRPS 252
PPT P QG + G P G G QP S G +C+ +
Sbjct: 91 PPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQN 150
Query: 253 LAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEA 312
+P S + + ++GG G PG A P G
Sbjct: 151 YSPQYDSYDVKSGVAVGGLAGY---------------------PGPAGPPGPPGPPGTSG 189
Query: 313 EGGDGDGEGCSGPPSAPASQA-------------------------------RALPPPPY 341
G G GPP P R LP PP
Sbjct: 190 HPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPG 249
Query: 342 TTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAA-ALSGPWGSPPPPPEQIHSA 400
P P F + G + NG G GAP + L G G+P P + A
Sbjct: 250 IKGPAGIPGFPGMKGHRGFDGR---NGEKGETGAPGLKGENGLPGENGAPGPMGPR--GA 304
Query: 401 PGPR-RPA-PALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLP-------PPTPPPTLQP 451
PG R RP P ++G+P PGPPG P P P P +
Sbjct: 305 PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGA 364
Query: 452 PALQPTPLPVAPPLTPGLGHKESALAPTAAPAL--PPALAADQAPAPSPAPAPTVAEPSP 509
P + P P GH A P P + P + PA P + P
Sbjct: 365 PGQRGEPGP--------QGH-AGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGP 415
Query: 510 PVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGD-GPR-ERATATVP--------DS 559
P A A A G R G K+G G+ GPR ER A +P D
Sbjct: 416 PGPAGANGA----------PGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDG 465
Query: 560 SGGGGGGSGAS-QTGAANTRAA 580
G G GA+ GAA R A
Sbjct: 466 KDGSPGEPGANGLPGAAGERGA 487
Score = 43.1 bits (100), Expect = 8e-04
Identities = 96/401 (23%), Positives = 120/401 (29%), Gaps = 93/401 (23%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMP-----------PPEEAAAVSAPPPAP 100
PG A PPG P P P + ER SP P P + + PP P
Sbjct: 839 PGVAGPPGGSGPAGP---PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGP 895
Query: 101 AGTLLPGPSKWQKPAG-TPVPRIRRLL----EASHRGQGDPPSLRPLKPPPPPRQLSVKD 155
+G+ PG PAG T P + +A G+ P + PP P L +
Sbjct: 896 SGS--PGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQG--PPGAPGPLGIAG 951
Query: 156 TVPRAPSQFPPPL--------------ETWKPPPP-LPSERQPADRRITPALATPASPPT 200
PP + E+ KP L ER P + P LA A P
Sbjct: 952 ITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG 1011
Query: 201 E--------------SQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKIT 246
S G ++G+ GAP H G PA
Sbjct: 1012 RDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRG------ 1065
Query: 247 FKSRPS--LAPPAASSSLAAKASLGGGGGGGLFAASGA--ISYAEVLKQGPLPPGAARPL 302
+S P+ P + S A G G G GA I P PG+ P
Sbjct: 1066 -ESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPA 1124
Query: 303 GEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPER 362
G+ G G SGPP + P P GP
Sbjct: 1125 GQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGP-----------------IGPPGPRG 1167
Query: 363 HFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGP 403
+ G+ G G P G G P PP APGP
Sbjct: 1168 NRGERGSEGSPGHP--------GQPGPPGPP-----GAPGP 1195
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 84.0 bits (206), Expect = 4e-16
Identities = 160/665 (24%), Positives = 209/665 (31%), Gaps = 146/665 (21%)
Query: 4 LQSEPSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVP 63
L P G KV PS + R P+ G+ PG+M
Sbjct: 562 LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ-----------------GARGQPGVMGF 604
Query: 64 REPQASPSTLPLTLERPSPVMP-----PPEEAAAVSAPPPAPAGTL-------LPGPSKW 111
P+ + E+ P P P ++ +A PP PAG PGPS +
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664
Query: 112 QKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTV-PRAPSQFP----- 165
Q G P P G+G P + + P + V PR FP
Sbjct: 665 QGLPGPPGPP----------GEGGKPGDQGV-----PGEAGAPGLVGPRGERGFPGERGS 709
Query: 166 PPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGG-APPHA 224
P + + P LP + + PA PP +Q P QG R G A P
Sbjct: 710 PGAQGLQGPRGLPGTPGTDGPK---GASGPAGPPG-AQGPPGLQGMPGERGAAGIAGPKG 765
Query: 225 GEGEMAQPA-------DSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLF 277
G++ + D GL+ + PP + + K +G G G
Sbjct: 766 DRGDVGEKGPEGAPGKDGGRGLT----------GPIGPPGPAGANGEKGEVGPPGPAGSA 815
Query: 278 AASGAISY-AEVLKQGPL----PPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQ 332
A GA E GP PPGA G + + GD G GP AP Q
Sbjct: 816 GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 875
Query: 333 AR-----------ALPPPPYTTFPGSKPKFDWVSA--------PDGPERHFRFNGAGGGI 373
A PP T FPG+ + + P GP GA G
Sbjct: 876 GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS 935
Query: 374 GAPRRRAA-ALSGPWGSP----PPPPEQIHSAPGPRRPAPALLAPPTFIFPAP------- 421
G P R L GP G P P + A GP P P LA I P
Sbjct: 936 GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP--PGPQGLAGQRGIVGLPGQRGERG 993
Query: 422 ------TNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQP----TPLPVAPPLTPGLGH 471
+GEP + G PG P P PP L PA +P +P PP G
Sbjct: 994 FPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAG 1053
Query: 472 KESALAPTAAPALPPALAADQAPAPS----------------------PAPAPTVAEPSP 509
+ T A P A +P P+ PA A + P
Sbjct: 1054 VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG 1113
Query: 510 PVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGD----GPRERATATVPDSSGGGGG 565
P A P + + ++G +G G GD GP + P G G
Sbjct: 1114 PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1173
Query: 566 GSGAS 570
GA+
Sbjct: 1174 KDGAN 1178
Score = 63.9 bits (154), Expect = 4e-10
Identities = 151/570 (26%), Positives = 180/570 (31%), Gaps = 105/570 (18%)
Query: 52 PGSATPPGLMVPRE-PQASPSTLPLTLE-------RPSPVMPP-PEEAAAVSAPPPAPAG 102
PG PG M PR P T P +P P PP P A P AP
Sbjct: 314 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 373
Query: 103 TLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPS 162
GP+ + P G PR G P S P P D +P A
Sbjct: 374 KGEAGPTGARGPEGAQGPRGE---------PGTPGSPGPAGASGNPGT----DGIPGAKG 420
Query: 163 QFPPPLETWKPP---PPLPSERQPADRRITPALAT--PASPPTESQAGPRNQGQTAGRAR 217
P P P P Q A + P T P + + GP+ + AG
Sbjct: 421 SAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ- 479
Query: 218 GGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLF 277
GAP AGE E + A E G + P A + G G GL
Sbjct: 480 -GAPGPAGE-EGKRGARGEPG-------------GVGPIGPPGERGAPGNRGFPGQDGLA 524
Query: 278 AASGAISYAEVLKQGPL----PPGA----ARPLGEVSRGAQEAEGGDGDG--EGCSGPPS 327
GA ++GP P GA RP GA+ G GD +G GP
Sbjct: 525 GPKGAPG-----ERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG 579
Query: 328 APASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPW 387
AP R PP P G++ G F G G G P + +G
Sbjct: 580 APGEDGRPGPPGPQ----GAR----------GQPGVMGFPGPKGANGEPGK-----AGEK 620
Query: 388 GSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPP 447
G P P + PG A PP PA GE PGP G Q LP PP PP
Sbjct: 621 GLPGAPG--LRGLPGKDGETGAA-GPPGPAGPAGERGEQGAPGPSGFQGLP--GPPGPPG 675
Query: 448 TLQPPALQPTPLPV-APPLTPGLGHK-----------ESALAPTAAPALPPALAADQAPA 495
P Q P AP L G + + P P P A
Sbjct: 676 EGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 735
Query: 496 PSPAP---APTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHG-DGPRER 551
P+ P P + P A A P R + G + GA KDG G GP
Sbjct: 736 PAGPPGAQGPPGLQGMPGERGAAGIAGP--KGDRGDVGEKGPEGAPGKDGGRGLTGP--- 790
Query: 552 ATATVPDSSGGGGGGSGASQTGAANTRAAR 581
P +G G G A + AR
Sbjct: 791 --IGPPGPAGANGEKGEVGPPGPAGSAGAR 818
Score = 60.8 bits (146), Expect = 4e-09
Identities = 104/388 (26%), Positives = 127/388 (32%), Gaps = 68/388 (17%)
Query: 106 PGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFP 165
PGP Q P+G P P+ G P R + PP P A +
Sbjct: 863 PGP---QGPSGAPGPQ-------GPTGVTGPKGARGAQGPPGATGF------PGAAGRVG 906
Query: 166 PPLETWKPPPPLP-------------SERQPADRRITPALATPASPPTE----------- 201
PP P PP P + P R P L PA PP E
Sbjct: 907 PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG 966
Query: 202 SQAGPRNQGQTAGRARGGAPPHAGE-GEMAQPADS-ESGLSLLCKITFKSRPS--LAPPA 257
++ P QG R G P GE G P S E G + P + PP
Sbjct: 967 AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG 1026
Query: 258 ASSSLAAKASLGGGGGGGLFAASGAISY-AEVLKQGPL-PPGAARPLGEVSRGAQEAEGG 315
+ G G G GA + + G + PGA P G + G
Sbjct: 1027 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086
Query: 316 DGDGEGCSGP--PSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPER----HFRFNGA 369
D G GP PS PA AR + P P+ D A + ER H F G
Sbjct: 1087 DRGEAGAQGPMGPSGPAG-ARGIQGP-------QGPRGDKGEAGEPGERGLKGHRGFTGL 1138
Query: 370 GGGIGAPR----RRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGE 425
G G P + A+ +GP G PP S P + PP P +GE
Sbjct: 1139 QGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG---PRGRSGE 1195
Query: 426 PMRPGPPGLQELPPLPPPTPPPTLQPPA 453
GPPG PP PP P P + A
Sbjct: 1196 TGPAGPPG-NPGPPGPPGPPGPGIDMSA 1222
Score = 56.2 bits (134), Expect = 9e-08
Identities = 133/558 (23%), Positives = 172/558 (30%), Gaps = 128/558 (22%)
Query: 52 PGSATPPGLMVPREPQA------SPSTLPLTLERPSPVMPP---PEEAAAVSAPPPAPAG 102
PG A PGL+ PR + SP L R P P P+ A+ + PP A
Sbjct: 686 PGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 745
Query: 103 TLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPS------LRPLKPPPPPRQLSVKDT 156
L G + AG P+ R +G P P+ PP P K
Sbjct: 746 PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGE 805
Query: 157 VPRAPSQFPPPLETWKPPPPLPS---ERQPADRRIT--PALATPASPP-TESQAGPRN-Q 209
V PP P S P +R T P A A PP + Q G + Q
Sbjct: 806 VG--------------PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 851
Query: 210 GQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLG 269
G+ + GAP G P +G++ +R + PP A+ A +G
Sbjct: 852 GEAGQKGDAGAPGPQGPSGAPGP-QGPTGVTG----PKGARGAQGPPGATGFPGAAGRVG 906
Query: 270 GGGGGGLFAASGAISYAEVLKQGPL-------PPGAARP---LGEVSRGAQEAEGGDGDG 319
G G G + K GP PPG A G ++ E GD
Sbjct: 907 PPGSNGNPGPPGPPGPSG--KDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGP 964
Query: 320 EGCSGPPS------------------------------------APASQARALPP----P 339
G GPP AP + PP P
Sbjct: 965 SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP 1024
Query: 340 PYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHS 399
P T P +P + DGP +GA G + R A+ P G+P PP +
Sbjct: 1025 PGLTGPAGEPGREGSPGADGPPGR---DGAAG-VKGDRGETGAVGAP-GAPGPPGSPGPA 1079
Query: 400 AP----------------GPRRPAPA--LLAPPTFIFPAPTNGEPMRPGP---------P 432
P GP PA A + P P GE PG
Sbjct: 1080 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG---PRGDKGEAGEPGERGLKGHRGFT 1136
Query: 433 GLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQ 492
GLQ LP P P+ PA P P+ P + + P P + +
Sbjct: 1137 GLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGET 1196
Query: 493 APAPSPAPAPTVAEPSPP 510
PA P P PP
Sbjct: 1197 GPAGPPGNPGPPGPPGPP 1214
Score = 51.6 bits (122), Expect = 2e-06
Identities = 114/464 (24%), Positives = 147/464 (31%), Gaps = 85/464 (18%)
Query: 173 PPPPLPSERQPADRRITPALATPASPPTESQAG-PRNQGQTAGRARGGAPPHAGE--GEM 229
P P + DR P + + G P N G G P G +M
Sbjct: 124 PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQM 183
Query: 230 AQPADSESGLSLLCKITFKSRPS--LAPPAASSSLAAKASLGGGGGGGLFAASGAISYAE 287
A D ++G + L + P PP + + + G G G SG +
Sbjct: 184 AGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP-- 241
Query: 288 VLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGS 347
+ P PPG GE + + E G +G G P P PG
Sbjct: 242 --RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPG-------------LPGV 286
Query: 348 KPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAP----GP 403
K + DG + G G G+P + GP G P E+ + P G
Sbjct: 287 KGHRGYPGL-DGAKGEAGAPGVKGESGSPGENGS--PGPMGPRGLPGERGRTGPAGAAGA 343
Query: 404 R----RPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQP---PALQP 456
R +P PA PP + PA G P PG G E P P P P
Sbjct: 344 RGNDGQPGPA--GPPGPVGPAGGPGFPGAPGAKG--EAGPTGARGPEGAQGPRGEPGTPG 399
Query: 457 TPLPVAPPLTPGL----GHKESALAPTAAPALPPALAADQAPAPSPAPA----------- 501
+P P PG G K SA AP A A P + P P P A
Sbjct: 400 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGA--PGFPGPRGP-PGPQGATGPLGPKGQTG 456
Query: 502 -PTVA----------EPSP--PVSAPAPAAAPIKTRTR------------RNKGSRAARG 536
P +A EP P P AP PA K R +G+ RG
Sbjct: 457 EPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRG 516
Query: 537 ATRKDGLHG--DGPRERATATVPDSSGGGGGGSGASQTGAANTR 578
+DGL G P ER + + G G + G R
Sbjct: 517 FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560
Score = 48.5 bits (114), Expect = 2e-05
Identities = 75/299 (25%), Positives = 88/299 (29%), Gaps = 42/299 (14%)
Query: 295 PPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWV 354
PPG P GE + G+ G G P + PP P PG
Sbjct: 121 PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGP----PGP------- 169
Query: 355 SAPDGPERHFRFNGAGG-GIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAP 413
P G +F AGG A + + GP G GPR P AP
Sbjct: 170 PGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG-----------PMGPRGPPGPAGAP 218
Query: 414 PTFIFPAPTNGEPMRPGPPGLQ-ELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHK 472
P G P PG PG+ + P PP PP P PG
Sbjct: 219 G----PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG---P 271
Query: 473 ESALAPTAAPALP--------PALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTR 524
+ A P LP P L + A +P P +P P
Sbjct: 272 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN-GSPGPMGPRGLPG 330
Query: 525 TRRNKGSRAARGATRKDGLHGDG--PRERATATVPDSSGGGGGGSGASQTGAANTRAAR 581
R G A GA DG G P A P G G A TGA A+
Sbjct: 331 ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 389
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 84.0 bits (206), Expect = 4e-16
Identities = 160/665 (24%), Positives = 209/665 (31%), Gaps = 146/665 (21%)
Query: 4 LQSEPSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVP 63
L P G KV PS + R P+ G+ PG+M
Sbjct: 493 LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ-----------------GARGQPGVMGF 535
Query: 64 REPQASPSTLPLTLERPSPVMP-----PPEEAAAVSAPPPAPAGTL-------LPGPSKW 111
P+ + E+ P P P ++ +A PP PAG PGPS +
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595
Query: 112 QKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTV-PRAPSQFP----- 165
Q G P P G+G P + + P + V PR FP
Sbjct: 596 QGLPGPPGPP----------GEGGKPGDQGV-----PGEAGAPGLVGPRGERGFPGERGS 640
Query: 166 PPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGG-APPHA 224
P + + P LP + + PA PP +Q P QG R G A P
Sbjct: 641 PGAQGLQGPRGLPGTPGTDGPK---GASGPAGPPG-AQGPPGLQGMPGERGAAGIAGPKG 696
Query: 225 GEGEMAQPA-------DSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLF 277
G++ + D GL+ + PP + + K +G G G
Sbjct: 697 DRGDVGEKGPEGAPGKDGGRGLT----------GPIGPPGPAGANGEKGEVGPPGPAGSA 746
Query: 278 AASGAISY-AEVLKQGPL----PPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQ 332
A GA E GP PPGA G + + GD G GP AP Q
Sbjct: 747 GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 806
Query: 333 AR-----------ALPPPPYTTFPGSKPKFDWVSA--------PDGPERHFRFNGAGGGI 373
A PP T FPG+ + + P GP GA G
Sbjct: 807 GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS 866
Query: 374 GAPRRRAA-ALSGPWGSP----PPPPEQIHSAPGPRRPAPALLAPPTFIFPAP------- 421
G P R L GP G P P + A GP P P LA I P
Sbjct: 867 GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP--PGPQGLAGQRGIVGLPGQRGERG 924
Query: 422 ------TNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQP----TPLPVAPPLTPGLGH 471
+GEP + G PG P P PP L PA +P +P PP G
Sbjct: 925 FPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAG 984
Query: 472 KESALAPTAAPALPPALAADQAPAPS----------------------PAPAPTVAEPSP 509
+ T A P A +P P+ PA A + P
Sbjct: 985 VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG 1044
Query: 510 PVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGD----GPRERATATVPDSSGGGGG 565
P A P + + ++G +G G GD GP + P G G
Sbjct: 1045 PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1104
Query: 566 GSGAS 570
GA+
Sbjct: 1105 KDGAN 1109
Score = 63.9 bits (154), Expect = 4e-10
Identities = 151/570 (26%), Positives = 180/570 (31%), Gaps = 105/570 (18%)
Query: 52 PGSATPPGLMVPRE-PQASPSTLPLTLE-------RPSPVMPP-PEEAAAVSAPPPAPAG 102
PG PG M PR P T P +P P PP P A P AP
Sbjct: 245 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 304
Query: 103 TLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPS 162
GP+ + P G PR G P S P P D +P A
Sbjct: 305 KGEAGPTGARGPEGAQGPRGE---------PGTPGSPGPAGASGNPGT----DGIPGAKG 351
Query: 163 QFPPPLETWKPP---PPLPSERQPADRRITPALAT--PASPPTESQAGPRNQGQTAGRAR 217
P P P P Q A + P T P + + GP+ + AG
Sbjct: 352 SAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ- 410
Query: 218 GGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLF 277
GAP AGE E + A E G + P A + G G GL
Sbjct: 411 -GAPGPAGE-EGKRGARGEPG-------------GVGPIGPPGERGAPGNRGFPGQDGLA 455
Query: 278 AASGAISYAEVLKQGPL----PPGA----ARPLGEVSRGAQEAEGGDGDG--EGCSGPPS 327
GA ++GP P GA RP GA+ G GD +G GP
Sbjct: 456 GPKGAPG-----ERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG 510
Query: 328 APASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPW 387
AP R PP P G++ G F G G G P + +G
Sbjct: 511 APGEDGRPGPPGPQ----GAR----------GQPGVMGFPGPKGANGEPGK-----AGEK 551
Query: 388 GSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPP 447
G P P + PG A PP PA GE PGP G Q LP PP PP
Sbjct: 552 GLPGAPG--LRGLPGKDGETGAA-GPPGPAGPAGERGEQGAPGPSGFQGLP--GPPGPPG 606
Query: 448 TLQPPALQPTPLPV-APPLTPGLGHK-----------ESALAPTAAPALPPALAADQAPA 495
P Q P AP L G + + P P P A
Sbjct: 607 EGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 666
Query: 496 PSPAP---APTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHG-DGPRER 551
P+ P P + P A A P R + G + GA KDG G GP
Sbjct: 667 PAGPPGAQGPPGLQGMPGERGAAGIAGP--KGDRGDVGEKGPEGAPGKDGGRGLTGP--- 721
Query: 552 ATATVPDSSGGGGGGSGASQTGAANTRAAR 581
P +G G G A + AR
Sbjct: 722 --IGPPGPAGANGEKGEVGPPGPAGSAGAR 749
Score = 60.8 bits (146), Expect = 4e-09
Identities = 104/388 (26%), Positives = 127/388 (32%), Gaps = 68/388 (17%)
Query: 106 PGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFP 165
PGP Q P+G P P+ G P R + PP P A +
Sbjct: 794 PGP---QGPSGAPGPQ-------GPTGVTGPKGARGAQGPPGATGF------PGAAGRVG 837
Query: 166 PPLETWKPPPPLP-------------SERQPADRRITPALATPASPPTE----------- 201
PP P PP P + P R P L PA PP E
Sbjct: 838 PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG 897
Query: 202 SQAGPRNQGQTAGRARGGAPPHAGE-GEMAQPADS-ESGLSLLCKITFKSRPS--LAPPA 257
++ P QG R G P GE G P S E G + P + PP
Sbjct: 898 AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG 957
Query: 258 ASSSLAAKASLGGGGGGGLFAASGAISY-AEVLKQGPL-PPGAARPLGEVSRGAQEAEGG 315
+ G G G GA + + G + PGA P G + G
Sbjct: 958 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017
Query: 316 DGDGEGCSGP--PSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPER----HFRFNGA 369
D G GP PS PA AR + P P+ D A + ER H F G
Sbjct: 1018 DRGEAGAQGPMGPSGPAG-ARGIQGP-------QGPRGDKGEAGEPGERGLKGHRGFTGL 1069
Query: 370 GGGIGAPR----RRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGE 425
G G P + A+ +GP G PP S P + PP P +GE
Sbjct: 1070 QGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG---PRGRSGE 1126
Query: 426 PMRPGPPGLQELPPLPPPTPPPTLQPPA 453
GPPG PP PP P P + A
Sbjct: 1127 TGPAGPPG-NPGPPGPPGPPGPGIDMSA 1153
Score = 56.2 bits (134), Expect = 9e-08
Identities = 133/558 (23%), Positives = 172/558 (30%), Gaps = 128/558 (22%)
Query: 52 PGSATPPGLMVPREPQA------SPSTLPLTLERPSPVMPP---PEEAAAVSAPPPAPAG 102
PG A PGL+ PR + SP L R P P P+ A+ + PP A
Sbjct: 617 PGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 676
Query: 103 TLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPS------LRPLKPPPPPRQLSVKDT 156
L G + AG P+ R +G P P+ PP P K
Sbjct: 677 PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGE 736
Query: 157 VPRAPSQFPPPLETWKPPPPLPS---ERQPADRRIT--PALATPASPP-TESQAGPRN-Q 209
V PP P S P +R T P A A PP + Q G + Q
Sbjct: 737 VG--------------PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 782
Query: 210 GQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLG 269
G+ + GAP G P +G++ +R + PP A+ A +G
Sbjct: 783 GEAGQKGDAGAPGPQGPSGAPGP-QGPTGVTG----PKGARGAQGPPGATGFPGAAGRVG 837
Query: 270 GGGGGGLFAASGAISYAEVLKQGPL-------PPGAARP---LGEVSRGAQEAEGGDGDG 319
G G G + K GP PPG A G ++ E GD
Sbjct: 838 PPGSNGNPGPPGPPGPSG--KDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGP 895
Query: 320 EGCSGPPS------------------------------------APASQARALPP----P 339
G GPP AP + PP P
Sbjct: 896 SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP 955
Query: 340 PYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHS 399
P T P +P + DGP +GA G + R A+ P G+P PP +
Sbjct: 956 PGLTGPAGEPGREGSPGADGPPGR---DGAAG-VKGDRGETGAVGAP-GAPGPPGSPGPA 1010
Query: 400 AP----------------GPRRPAPA--LLAPPTFIFPAPTNGEPMRPGP---------P 432
P GP PA A + P P GE PG
Sbjct: 1011 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG---PRGDKGEAGEPGERGLKGHRGFT 1067
Query: 433 GLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQ 492
GLQ LP P P+ PA P P+ P + + P P + +
Sbjct: 1068 GLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGET 1127
Query: 493 APAPSPAPAPTVAEPSPP 510
PA P P PP
Sbjct: 1128 GPAGPPGNPGPPGPPGPP 1145
Score = 51.6 bits (122), Expect = 2e-06
Identities = 114/464 (24%), Positives = 147/464 (31%), Gaps = 85/464 (18%)
Query: 173 PPPPLPSERQPADRRITPALATPASPPTESQAG-PRNQGQTAGRARGGAPPHAGE--GEM 229
P P + DR P + + G P N G G P G +M
Sbjct: 55 PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQM 114
Query: 230 AQPADSESGLSLLCKITFKSRPS--LAPPAASSSLAAKASLGGGGGGGLFAASGAISYAE 287
A D ++G + L + P PP + + + G G G SG +
Sbjct: 115 AGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP-- 172
Query: 288 VLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGS 347
+ P PPG GE + + E G +G G P P PG
Sbjct: 173 --RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPG-------------LPGV 217
Query: 348 KPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAP----GP 403
K + DG + G G G+P + GP G P E+ + P G
Sbjct: 218 KGHRGYPGL-DGAKGEAGAPGVKGESGSPGENGS--PGPMGPRGLPGERGRTGPAGAAGA 274
Query: 404 R----RPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQP---PALQP 456
R +P PA PP + PA G P PG G E P P P P
Sbjct: 275 RGNDGQPGPA--GPPGPVGPAGGPGFPGAPGAKG--EAGPTGARGPEGAQGPRGEPGTPG 330
Query: 457 TPLPVAPPLTPGL----GHKESALAPTAAPALPPALAADQAPAPSPAPA----------- 501
+P P PG G K SA AP A A P + P P P A
Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGA--PGFPGPRGP-PGPQGATGPLGPKGQTG 387
Query: 502 -PTVA----------EPSP--PVSAPAPAAAPIKTRTR------------RNKGSRAARG 536
P +A EP P P AP PA K R +G+ RG
Sbjct: 388 EPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRG 447
Query: 537 ATRKDGLHG--DGPRERATATVPDSSGGGGGGSGASQTGAANTR 578
+DGL G P ER + + G G + G R
Sbjct: 448 FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 491
Score = 48.5 bits (114), Expect = 2e-05
Identities = 75/299 (25%), Positives = 88/299 (29%), Gaps = 42/299 (14%)
Query: 295 PPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWV 354
PPG P GE + G+ G G P + PP P PG
Sbjct: 52 PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGP----PGP------- 100
Query: 355 SAPDGPERHFRFNGAGG-GIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAP 413
P G +F AGG A + + GP G GPR P AP
Sbjct: 101 PGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG-----------PMGPRGPPGPAGAP 149
Query: 414 PTFIFPAPTNGEPMRPGPPGLQ-ELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHK 472
P G P PG PG+ + P PP PP P PG
Sbjct: 150 G----PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG---P 202
Query: 473 ESALAPTAAPALP--------PALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTR 524
+ A P LP P L + A +P P +P P
Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN-GSPGPMGPRGLPG 261
Query: 525 TRRNKGSRAARGATRKDGLHGDG--PRERATATVPDSSGGGGGGSGASQTGAANTRAAR 581
R G A GA DG G P A P G G A TGA A+
Sbjct: 262 ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 320
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 84.0 bits (206), Expect = 4e-16
Identities = 117/439 (26%), Positives = 143/439 (32%), Gaps = 78/439 (17%)
Query: 87 PEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPP 146
P E A +AP P PAG PG Q+P G P PR RPL P
Sbjct: 78 PAEGAPGAAPEPPPAGRARPGGGGPQRP-GPPSPR------------------RPLVPAG 118
Query: 147 PPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGP 206
P PP +PPP E PA A A+ P + AGP
Sbjct: 119 P-----------------APPAAKLRPPP----EGSAGSCAPVPAAAAVAAGPEPAPAGP 157
Query: 207 -RNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAK 265
+ G A AR G P G G P + A P A+ +L
Sbjct: 158 AKPAGPAALAARAGPGPGPGPGPGPGPGPGKP----------------AGPGAAQTLNGS 201
Query: 266 ASLGGGGGGGLFAASGAISYAEVLKQGPLP-PGAARPLGEVSRGAQEAEGGDGDGEGCSG 324
A+L AA+ A+S LP P A P G V +
Sbjct: 202 AALLNSH----HAAAPAVSLVNNGPAALLPLPKPAAP-GTVIQTPPFVGAAAPPAPAAPS 256
Query: 325 PPSAPASQARALPPPPYTTFPGS------KPKFDWVSAPDGPERHFRFNGAGGGIG-APR 377
PP+APA A A PPP P + P +AP P NG G AP
Sbjct: 257 PPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA 316
Query: 378 RRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALL---APP---TFIFPAPTNGEPMRPGP 431
A +G G P P APG + +P + APP T P +
Sbjct: 317 PAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG 376
Query: 432 PGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAAD 491
P +Q P P PPP P P A +T L +A L P + A
Sbjct: 377 PTMQGALPSPAAVPPPA--PGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAP 434
Query: 492 QAPAPSPAPAPTVAEPSPP 510
+ P P P PP
Sbjct: 435 RLPQPPQNPTNIQNFQLPP 453
Score = 82.0 bits (201), Expect = 2e-15
Identities = 119/424 (28%), Positives = 141/424 (33%), Gaps = 80/424 (18%)
Query: 189 TPALATPASP--PTESQAGPRNQGQTAGRAR--GGAPPHAGEGEMAQPADSESGLSLLCK 244
+PA A A P P E G + AGRAR GG P G +P
Sbjct: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGP------ 119
Query: 245 ITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGE 304
APPAA + S G A + A P P G A+P G
Sbjct: 120 ---------APPAAKLRPPPEGSAGS-------CAPVPAAAAVAAGPEPAPAGPAKPAGP 163
Query: 305 VSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHF 364
A A G G G G GP P PG P GP
Sbjct: 164 A---ALAARAGPGPGPG-PGPGPGPG--------------PGK---------PAGPGAAQ 196
Query: 365 RFNGAGGGIGAPRRRAAALS----GPWGSPPPPPEQIHSAPGPRRPAPALL---APPTFI 417
NG+ + + A A+S GP P P +APG P + APP
Sbjct: 197 TLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP---AAPGTVIQTPPFVGAAAPPAPA 253
Query: 418 FPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALA 477
P+P P P P PP PPP P TL P P P A P P ++ +
Sbjct: 254 APSP----PAAPAPAAPAAAPP-PPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGS 308
Query: 478 PTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAP----AAAPIKTRTRRNKG--S 531
AAPA PA + P P A P+P V A +P AAP +T G S
Sbjct: 309 AGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPAS 368
Query: 532 RAAR---GATRKDGLHGDG---PRERATATVPDSSGGGGGGSGASQTGAANTRAARHWLP 585
AA G T + L P T T G S+T A T R L
Sbjct: 369 TAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLT 428
Query: 586 FQVL 589
VL
Sbjct: 429 PTVL 432
Score = 67.4 bits (163), Expect = 4e-11
Identities = 139/558 (24%), Positives = 178/558 (31%), Gaps = 95/558 (17%)
Query: 1 MGN--LQSEPSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPP 58
+GN + P+ G+ P++ AP + PE G G PG +P
Sbjct: 58 LGNHVVSGSPAGAAGAGPAAPAEGAPGAA------PEPPPAGRARPGGGGPQRPGPPSPR 111
Query: 59 GLMVPREPQASPSTLPLTLERPSP------VMPPPEEAAAVSAPPPAPAGTLLP------ 106
+VP P + L RP P P P AA + P PAPAG P
Sbjct: 112 RPLVPAGPAPPAAKL-----RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL 166
Query: 107 ----GPSKWQKPAGTPVPRIRR---------------LLEASHRG-------QGDPPSLR 140
GP P P P + LL + H P +L
Sbjct: 167 AARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALL 226
Query: 141 PLKPPPPPRQLSVKDTVPRAPSQFPP-PLETWKPPPPLPSERQPADRRITPALAT----- 194
PL P P +V T P + PP P P P P+ A PA AT
Sbjct: 227 PLPKPAAPG--TVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP 284
Query: 195 --PASPPTESQAGPRNQGQTAGRARGGAP---PHAG--EGEMAQPADSESGLSLLCKITF 247
PA PPT + A P G + G AP P AG G QP + + +
Sbjct: 285 GHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKA 344
Query: 248 KS--RPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEV 305
+S R A P A+ +LAA A++ A QG LP AA P
Sbjct: 345 ESPKRVVQAAPPAAQTLAASGP----------ASTAASMVIGPTMQGALPSPAAVPPPAP 394
Query: 306 SRGAQEAEGGDGD-GEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHF 364
+G G + S P+A S RA P T P+ P P
Sbjct: 395 GTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTP--TVLAPRLPQ-----PPQNPTNIQ 447
Query: 365 RFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPR---RPAPALLAPPTFIFPAP 421
F G + L P + Q H+ P RPA APP I
Sbjct: 448 NFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQ 507
Query: 422 TNGEP-----MRPGPPGLQELPPLPPPTPPPTLQ-PPALQPTPLPVAPPLTPGLGHKESA 475
G P + P Q P TLQ P +QP + T LG +
Sbjct: 508 APGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAV 567
Query: 476 LAPTAAPALPPALAADQA 493
T +P A A
Sbjct: 568 QTGTPQRTVPGATTTSSA 585
Score = 42.0 bits (97), Expect = 0.002
Identities = 53/172 (30%), Positives = 64/172 (37%), Gaps = 40/172 (23%)
Query: 356 APDGPERHFRFNGAGGG---IGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLA 412
AP PE GA G G+P +G G+ P P + APG A
Sbjct: 44 APRTPEVRAAAAGALGNHVVSGSP-------AGAAGAGPAAPAE--GAPG------AAPE 88
Query: 413 PPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHK 472
PP P G P RPGPP + PL P P P PA + P P
Sbjct: 89 PPPAGRARPGGGGPQRPGPPSPRR--PLVPAGPAP----PAAKLRPPPEG---------S 133
Query: 473 ESALAPTAAPALPPALAADQAPAPS----PAPAPTVAEPSPPVSAPAPAAAP 520
+ AP A A A+AA PAP+ PA +A + P P P P
Sbjct: 134 AGSCAPVPAAA---AVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGP 182
Score = 38.5 bits (88), Expect = 0.020
Identities = 46/153 (30%), Positives = 49/153 (32%), Gaps = 30/153 (19%)
Query: 462 APPLTPGLGHKESALAPTAAPALPPALAA------DQAPA-PSP-------APAPTVAEP 507
A P P G AP AAP PPA A Q P PSP PAP A+
Sbjct: 73 AGPAAPAEG------APGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
Query: 508 SPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGS 567
PP A + AP+ G A K GP A P G G G
Sbjct: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPA----GPAALAARAGPGPGPGPGPGP 182
Query: 568 GASQTGAANTRAARHWLPFQVLNSCPCKCYCHH 600
G A AA Q LN HH
Sbjct: 183 GPGPGKPAGPGAA------QTLNGSAALLNSHH 209
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 83.6 bits (205), Expect = 5e-16
Identities = 151/585 (25%), Positives = 193/585 (32%), Gaps = 156/585 (26%)
Query: 48 GVWFPGSAT-----PPGL-MVPREPQASPSTL---PLTLERPSP--VMPPPEEAAAVSAP 96
G + PG A+ PGL + P +P PST+ PL L + P PPP P
Sbjct: 991 GPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPP---P 1047
Query: 97 PPAPAGTLLPG----------PSKWQKPAG--------TPVPRIRRLLEASHRGQGDPPS 138
PPAPA G P K K + P ++L + + D
Sbjct: 1048 PPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDK 1107
Query: 139 --------LRPLKPP---------PPPRQLSVKDTVPRAPSQFPP------PLETWKPPP 175
L P + P P L D P P P P + + P
Sbjct: 1108 ADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGP 1167
Query: 176 PLPSERQPADRRITPALATPASP--PTESQAGPRNQGQTAGRAR---GG----------- 219
P P R P A PAS PT+ PR +G+ GR GG
Sbjct: 1168 PRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKI 1227
Query: 220 --APPHAGEGEMAQPADSESGL---SLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGG 274
+ P AGEG D+ SG SL +T + + K+
Sbjct: 1228 KLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKS-------- 1279
Query: 275 GLFAASGAISYAEVLKQGPLPP-----GAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAP 329
G A S+ + LK G P G PL S PPS P
Sbjct: 1280 GFMA-----SFLDFLKSGKRHPPLYQAGLTPPLSPPK----------------SVPPSVP 1318
Query: 330 ASQARALPPP-PYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRR--------- 379
A + PP P P F A + E G G G +P +R
Sbjct: 1319 ARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESE----GLGLGCPSPCKRLDEELKRNL 1374
Query: 380 ------------------------AAALSGPWGSPPPPPEQIHSAPGPR-RPAPALLAPP 414
++A+S P P+ + GP PA A+ PP
Sbjct: 1375 ETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPP 1434
Query: 415 TF--IFPAPTNGEPMRPGPPGLQELPP-LPPPTPPPTLQPPALQPTPLPVAPPLTPGLGH 471
+ A +NG P PP L+E PP PPP P P QPP P P P P P +
Sbjct: 1435 PLPGLPSANSNGTPE---PPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAP 1491
Query: 472 KESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAP 516
S+ P P PP P P PA AP A P P +AP+P
Sbjct: 1492 TPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEP-AAPSP 1535
Score = 63.9 bits (154), Expect = 4e-10
Identities = 125/510 (24%), Positives = 165/510 (32%), Gaps = 114/510 (22%)
Query: 51 FPGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAA----VSAPPPAPAGTLLP 106
FP S+ P + P +P +L P PP V P+ A T+ P
Sbjct: 142 FPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTV-P 200
Query: 107 GPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRP--LKPPPPPRQLSVK-------DTV 157
+++ AG V L + G P RP PPPPPR L +
Sbjct: 201 SSLGFERLAGGGV------LGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAA 254
Query: 158 PRAPSQFPPPLETWK-----PPPP---LPSERQPADRRITPALATPASPPTESQAGPR-- 207
A Q P L + PPPP LP + PA A P PP + A
Sbjct: 255 AAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYL 314
Query: 208 -------NQGQTAGRA---RGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPA 257
+ G A A GG P G GE + K+ PS A
Sbjct: 315 SCGGSYPSMGHRANLACSPLGGGEPSPGAGEPS-----------------KAGPSGATAG 357
Query: 258 ASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDG 317
AS + GGGG GG G Y +++ S G + +GG G
Sbjct: 358 ASGRATGPEAAGGGGAGG-----GGGGYRPIIQ---------------SPGYKTGKGGYG 397
Query: 318 DGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPR 377
G PPPP +T + PK + P + +GAGG G
Sbjct: 398 AAAG-----------GATRPPPPRST---ATPKCQSLGGPAAAYATGKASGAGGAGG--- 440
Query: 378 RRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQEL 437
+A + P G P Q + A L P++ P P P PPGL
Sbjct: 441 -QAYSPGQPQGLLGP---QAYGQGFGGGQAQDLSKAPSYSGGPPQ--PPSGPPPPGLATC 494
Query: 438 PPLPPPTPPPTLQPPALQPTPLPVA---------PPLTPGLGHKESALAPTAAPALPPAL 488
P L +P P P A P L+ GH AL+ P +L
Sbjct: 495 QSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGH-SPALSGHGGGWGPSSL 553
Query: 489 AADQAPAPS----PAPAPTVAEPSPPVSAP 514
+PS P +P P V +P
Sbjct: 554 GGGGEASPSHIIRPLQSPPATGRPPGVGSP 583
Score = 61.6 bits (148), Expect = 2e-09
Identities = 116/473 (24%), Positives = 155/473 (32%), Gaps = 96/473 (20%)
Query: 64 REPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIR 123
R+ Q S S+ L+ P + P++ + PP APA + PGP P +
Sbjct: 1392 RDLQESISSAISALD--DPPLAGPKDTSTPDGPPLAPAAAV-PGP-----------PPLP 1437
Query: 124 RLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQP 183
L A+ G +PP L KPPP P P Q PPP PPPP P+ P
Sbjct: 1438 GLPSANSNGTPEPPLLE-EKPPPTP------PPAPTPQPQPPPP-----PPPPQPALPSP 1485
Query: 184 ADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLC 243
+ P ++P PP P AP A E A P+ + L
Sbjct: 1486 PP-LVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTR 1544
Query: 244 KITFKSRPSLAPPAASSSLAAKASLGGGGGGGLF--------AASGAISYAEVLKQGPLP 295
+ + A + A G GG G+F A S L+ G P
Sbjct: 1545 PLHLAKKQETAAVCGETDEEA----GESGGEGIFRERDEFVIRAEDIPSLKLALQTGREP 1600
Query: 296 PGAARPLGEVSRGAQE---AEGGDGDGEGC-SGPPSAPASQARALPPPPYTTFPGSKPKF 351
P P+ V + + E DG + C + A+ Y F + K
Sbjct: 1601 P----PIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKK 1656
Query: 352 DWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQI-----------HSA 400
D+V R A PW PP P + SA
Sbjct: 1657 DYV------------------------RVCARK-PWHRPPVPVRRSGQAKNPVSAGGSSA 1691
Query: 401 PGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPL- 459
P P+ PAP PP P T E PP ++ P P PP +P L+P
Sbjct: 1692 PPPKAPAP----PPKPETPEKTTSEK----PP--EQTPETAMPEPPAPEKPSLLRPVEKE 1741
Query: 460 PVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPS--PAPAPTVAEPSPP 510
+T G A + P A PA S P PT + PP
Sbjct: 1742 KEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPP 1794
Score = 59.3 bits (142), Expect = 1e-08
Identities = 109/432 (25%), Positives = 133/432 (30%), Gaps = 80/432 (18%)
Query: 134 GDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPP-PLPSERQPADRRITPAL 192
G PP +P PPPP + + +P Q L + P P P+ +P+L
Sbjct: 477 GGPP--QPPSGPPPPGLATCQSY---SPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSL 531
Query: 193 A--TPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPAD-------SESGLSLLC 243
+ T SP G G +P H + PA S
Sbjct: 532 SYSTGHSPALSGHGGGWGPSSLGGGGEA-SPSHIIRPLQSPPATGRPPGVGSPGAPGKYL 590
Query: 244 KITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEV----------LKQGP 293
S P LAPP A S A G G G A AE L Q P
Sbjct: 591 SSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAP 650
Query: 294 LPPGAARPLGEVSR-GAQEAEGGDGDGEGCSGPPSAPASQARALPPPPY--TTFPGSKPK 350
PP + G V GA +A G G G GPP P A+ P + + S
Sbjct: 651 SPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASL 710
Query: 351 FDWVSAP------------DGPERH------FRFNGAGGGIGAPRRRAAALSGPWGSPPP 392
+ +A GPER + G GA A P PPP
Sbjct: 711 DEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSP---PPP 767
Query: 393 PPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPP 452
PP + P P +G + G P L PL P PPP L P
Sbjct: 768 PPTAQSTQPTP-------------------HGLLLEAGGPDL----PLVLPPPPPQLLPS 804
Query: 453 ALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVS 512
L P P G+ E A A PP P P P P P E
Sbjct: 805 VLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPP-------PPPPPPPMPLQLEAHLRSH 857
Query: 513 APAPAAAPIKTR 524
PAA + R
Sbjct: 858 GLEPAAPSPRLR 869
Score = 55.5 bits (132), Expect = 2e-07
Identities = 90/340 (26%), Positives = 109/340 (32%), Gaps = 64/340 (18%)
Query: 139 LRPLKPPPPPRQLSVKDTV---------PRAPSQFPPPLETWKPPPPLPSERQPADRRIT 189
L+ PPPPP S + T P P PPP PP LPS A
Sbjct: 760 LQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPP-----PPQLLPSVLSHA----- 809
Query: 190 PALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKS 249
P+ P+ S+ G PP P E+ L
Sbjct: 810 -----PSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLR--------- 855
Query: 250 RPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGA 309
L P A S L + SL G + GA+ PLPP G+ G
Sbjct: 856 SHGLEPAAPSPRLRPEESLDPPGA--MQELLGALE--------PLPPAP----GDTGVGP 901
Query: 310 QEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGA 369
+EG D G S PS ++A P FP S + + S E F A
Sbjct: 902 PNSEGKDPAGAYRS--PSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAA 959
Query: 370 G--GGIGAPRRRAAALSGPWGSPPPPPEQIHSAP---------GPRRPAPALLAPPTFIF 418
G G P +G G PP PP P GP P L
Sbjct: 960 DDYGKAGPPEDEGDPKAGA-GPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPEL 1018
Query: 419 PAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTP 458
P+ N EP+ G + P PPP PPP PPA P
Sbjct: 1019 PSTVNAEPLGLIQSGPHQAAPPPPPPPPP---PPAPASEP 1055
Score = 52.8 bits (125), Expect = 1e-06
Identities = 45/170 (26%), Positives = 58/170 (34%), Gaps = 28/170 (16%)
Query: 52 PGSATPPGLMVPREPQASPSTLP---LTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGP 108
P +A P +P P A+ + P L E+P P PP PPP P LP P
Sbjct: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
Query: 109 SKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPL 168
P + P PP PL PPPPP +P P PP
Sbjct: 1486 PPLVAPTPSSPP---------------PP---PLPPPPPP-------AMPSPPPPPPPAA 1520
Query: 169 ETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARG 218
PP P+ P D + + E+ A + AG + G
Sbjct: 1521 APLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGG 1570
Score = 50.8 bits (120), Expect = 4e-06
Identities = 134/573 (23%), Positives = 170/573 (29%), Gaps = 163/573 (28%)
Query: 48 GVWFPGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPE-----------EAAAVSAP 96
G W P S G +ASPS + L+ P PP + SAP
Sbjct: 546 GGWGPSSLGGGG-------EASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAP 598
Query: 97 PPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDT 156
AP PG + AG ++G+GD L PP + ++
Sbjct: 599 FLAP-----PGAGSYAAGAG------------GYKGKGDGSELLAGPGGPPAERTEDEEF 641
Query: 157 VPRAPSQFPPPLETWKP------------------------PPPLPSE---RQPADRRIT 189
+ + Q P P T PP P E P +
Sbjct: 642 LIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQ 701
Query: 190 PALATPASPPTESQAG-----PRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCK 244
+ T AS + A R + + G RGG P EG +G L
Sbjct: 702 SVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETP---EGLATSVVHYGAGAKELGA 758
Query: 245 ITFKSRPSLAPPAASSSLAAKASLGGGGGGGL---FAASGAISYAEVLKQGPLPPGAARP 301
KS P P A S+ L GG L VL P P +A
Sbjct: 759 FLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASK 818
Query: 302 LGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPE 361
+G E DG PP P PPPP P E
Sbjct: 819 VG-----VHLLEPATRDGAPQPPPPPPP-------PPPPM---------------PLQLE 851
Query: 362 RHFRFNGAGGGIGAPRRRAAALSGPWGS--------PPPPPEQIHSAPGP---------- 403
H R +G +PR R P G+ P PP + GP
Sbjct: 852 AHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAG 911
Query: 404 --RRPAPALLAPPTFI------FPAPTNGEPMRPGPPGLQEL-------------PPLPP 442
R P+P P F+ FP + R P ++E+ PP
Sbjct: 912 AYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDE 971
Query: 443 PTPPPTLQPPALQPTPLPVAP----------PLTPGLGHKESALAPTAAPALPPALAAD- 491
P PP P P P P TPGLG L P P LP + A+
Sbjct: 972 GDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLG-----LDPNKPPELPSTVNAEP 1026
Query: 492 ----QAPAPSPAPAPTVAEPSPPVSAPAPAAAP 520
Q+ AP P P PP PAPA+ P
Sbjct: 1027 LGLIQSGPHQAAPPP----PPPPPPPPAPASEP 1055
Score = 42.7 bits (99), Expect = 0.001
Identities = 53/204 (25%), Positives = 70/204 (34%), Gaps = 40/204 (19%)
Query: 369 AGGGIGAPRRRAAALSGPWG----SPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNG 424
AGGG+ P A + P+ PPPPP + + + A A P N
Sbjct: 209 AGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNF 268
Query: 425 EPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPAL 484
PGPP + P +P + QP P PP L H S +
Sbjct: 269 SGAAPGPPPPERALPRQDTVIKHYQRPASAQPPP---PPPPAHALQHYLSCGGSYPSMGH 325
Query: 485 PPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLH 544
LA +P P+P EPS A P S A GA+ +
Sbjct: 326 RANLAC--SPLGGGEPSPGAGEPSK--------AGP----------SGATAGASGR---- 361
Query: 545 GDGPRERATATVPDSSGGGGGGSG 568
AT P+++GGGG G G
Sbjct: 362 ---------ATGPEAAGGGGAGGG 376
Score = 40.0 bits (92), Expect = 0.007
Identities = 85/389 (21%), Positives = 111/389 (28%), Gaps = 89/389 (22%)
Query: 279 ASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARAL-P 337
A+G +S +VL P + P S G + GG G GP P + P
Sbjct: 179 ANGLLSPHDVLHLKP----SQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDP 234
Query: 338 PPPYTTFPG-----SKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSG------- 385
PPP P + +A + + F+GA G P R
Sbjct: 235 PPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQR 294
Query: 386 -PWGSPPPPPEQIH----------SAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGL 434
PPPPP H S P A +P P+P GEP + GP G
Sbjct: 295 PASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGA 354
Query: 435 QELPPLPPPTPP---------------PTLQPPALQ----------------PTPLPVAP 463
P P +Q P + P P A
Sbjct: 355 TAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTAT 414
Query: 464 PLTPGLGHKESALAPTAA------------PALPPALAADQAPAP----------SPAPA 501
P LG +A A A P P L QA S AP+
Sbjct: 415 PKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPS 474
Query: 502 PTVAEPSPPVSAPAPAAAPIKTRTRRN--------KGSRAARGATRKDGLHGDGPRERAT 553
+ P PP P P A ++ + +G A GL P +
Sbjct: 475 YSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYS 534
Query: 554 ATVPDSSGGGGGGSGASQTGAANTRAARH 582
+ G GGG G S G + H
Sbjct: 535 TGHSPALSGHGGGWGPSSLGGGGEASPSH 563
Score = 38.9 bits (89), Expect = 0.015
Identities = 123/541 (22%), Positives = 162/541 (29%), Gaps = 113/541 (20%)
Query: 57 PPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAG 116
PP ++P +PS P + ++ P A PPP P
Sbjct: 797 PPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP---------------- 840
Query: 117 TPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPP 176
P P + LEA R G L P P P R D P L +P PP
Sbjct: 841 PPPPPMPLQLEAHLRSHG----LEPAAPSPRLRPEESLD----PPGAMQELLGALEPLPP 892
Query: 177 LPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSE 236
P + T PP P AG R +P A
Sbjct: 893 APGD-------------TGVGPPNSEGKDP------AGAYRSPSP-------QGTKAPRF 926
Query: 237 SGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQG---P 293
L+ +C SL S + GGG + +G K G P
Sbjct: 927 VPLTSIC-----FPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPP 981
Query: 294 LPPGAARPLGEVSRGAQEAEGGDGDGEGC--SGPPSAPAS-QARAL-------------- 336
P A P G G G + G G + PP P++ A L
Sbjct: 982 PGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPP 1041
Query: 337 -PPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPE 395
PPPP P S+PK GG+ +P + P
Sbjct: 1042 PPPPPPPPAPASEPK--------------------GGLTSP---IFCSTKPKKLLKTSSF 1078
Query: 396 QIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQ 455
+ P P L + F A E P ++ P P PAL
Sbjct: 1079 HLLRRRDPPFQTPKKLYAQEYEFEA---DEDKADVPADIRLNPRRLPDLVSSCRSRPALS 1135
Query: 456 PT-PLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAP 514
P + PP G + PT A P + P P PT A P+ SA
Sbjct: 1136 PLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGR-PRIRPLEVPTTAGPA---SAS 1191
Query: 515 APAAAPIKTRTR-RNKGSRAAR-GATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQT 572
P K R R R +G +A G TR + L + +VP + G G SG + +
Sbjct: 1192 TPTDGAKKPRGRGRGRGRKAEEAGGTRLEPL----KPLKIKLSVPKAGEGLGTSSGDAIS 1247
Query: 573 G 573
G
Sbjct: 1248 G 1248
Score = 32.3 bits (72), Expect = 1.4
Identities = 42/154 (27%), Positives = 56/154 (36%), Gaps = 28/154 (18%)
Query: 53 GSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAP--AGTLLPGPSK 110
GS+ PP P+ P P P T E+ + PP + PPAP L P +
Sbjct: 1688 GSSAPP----PKAPAPPPK--PETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKE 1741
Query: 111 WQKPAGTPVPRIRRLLEASHRGQGDP--------------PSLRPLK----PPPPPRQLS 152
+K T R R A+ Q P P RP K PPP R+
Sbjct: 1742 KEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKW 1801
Query: 153 VKDTVPRAPSQFPPP--LETWKPPPPLPSERQPA 184
+K+ A + PP + P PSE + A
Sbjct: 1802 LKEAGGNATAGGGPPGSSSDSESSPGAPSEDERA 1835
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 82.8 bits (203), Expect = 9e-16
Identities = 144/534 (26%), Positives = 178/534 (33%), Gaps = 79/534 (14%)
Query: 80 PSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDP-PS 138
P V P ++ A + PP PAG G Q PAG+P QG P P+
Sbjct: 604 PGAVGPAGKDGEAGAQGPPGPAGPA--GERGEQGPAGSP------------GFQGLPGPA 649
Query: 139 LRPLKPPPPPRQLSVKDTVPRAPSQ------FPPPLETWKPPPPLP---SERQPADRRIT 189
P + P Q D PS FP PP P + P +
Sbjct: 650 GPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAK 709
Query: 190 PALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQP--ADSESGLSLLCKITF 247
P +P SQ P QG R G P G+ A P AD G + +T
Sbjct: 710 GDAGAPGAPG--SQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLT- 766
Query: 248 KSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPL-PPGAARPLGEVS 306
+ PP + + K G G G A GA + + GP P G A P G
Sbjct: 767 ---GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPG--DRGEPGPPGPAGFAGPPGADG 821
Query: 307 RGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRF 366
+ + E GD +G +GPP PA A P PG+K GP F
Sbjct: 822 QPGAKGEPGDAGAKGDAGPP-GPAGPAGPPGPIGNVGAPGAK----GARGSAGPPGATGF 876
Query: 367 NGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAP-GPRRPA--PALLAPPTFIFPAPTN 423
GA G +G P A GP G P P ++ P G PA P + PP PA
Sbjct: 877 PGAAGRVGPPGPSGNA--GPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEK 934
Query: 424 GEP------MRPGPPGLQEL------------------PPLPPPTPPPTLQPPA----LQ 455
G P PG PG Q + P LP P+ P Q P+ +
Sbjct: 935 GSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGER 994
Query: 456 PTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPA 515
P P+ P PGL AP + D +P T P+ P AP
Sbjct: 995 GPPGPMGP---PGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET--GPAGPPGAPG 1049
Query: 516 PAAAPIKTRTRRNKGSRAARGATRKDGLHGD-GPRERATATVPDSSGGGGGGSG 568
AP G R G G G G R A P G G G
Sbjct: 1050 APGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQG 1103
Score = 80.1 bits (196), Expect = 6e-15
Identities = 145/567 (25%), Positives = 176/567 (31%), Gaps = 107/567 (18%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPP-----EEAAAVSAPPPAPAGTL-- 104
PG PG M PR L ER P P P + A +A PP P G
Sbjct: 292 PGENGAPGQMGPRG---------LPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGP 342
Query: 105 --LPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPS 162
PG + AG PR G P +R PP P + P A
Sbjct: 343 PGFPGAVGAKGEAGPQGPR----------GSEGPQGVRGEPGPPGPAGAAGPAGNPGADG 392
Query: 163 QFPPPLETWKP----PPPLPSERQPADRRITPALATPASPP-----TESQAGPRNQGQTA 213
Q P P P R P+ + P PP + P ++G T
Sbjct: 393 QPGAKGANGAPGIAGAPGFPGARGPSGPQ------GPGGPPGPKGNSGEPGAPGSKGDTG 446
Query: 214 GRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGG 273
+ G P G PA E R + P + GG G
Sbjct: 447 AK---GEPGPVGVQGPPGPAGEEG-----------KRGARGEPGPTGLPGPPGERGGPGS 492
Query: 274 GGLFAASGAISYAEVLKQGPL----PPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAP 329
G A G +GP PG A P G + E G +G +G P +P
Sbjct: 493 RGFPGADGVAG-----PKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSP 547
Query: 330 ASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAA----LSG 385
+ PP P D P GP G G +G P + AA +G
Sbjct: 548 GPDGKTGPPGPAGQ--------DGRPGPPGPP---GARGQAGVMGFPGPKGAAGEPGKAG 596
Query: 386 PWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTP 445
G P PP P + PP PA GE G PG Q LP P P
Sbjct: 597 ERGVPGPPGA---VGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLP--GPAGP 651
Query: 446 PPTLQPPALQPTPLPVAPPLTPGLGHK-----ESALAPTAAPALPPALAADQAPAPSPAP 500
P P Q P + P G + E + PA P A+ AP A
Sbjct: 652 PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP--RGANGAPGNDGAK 709
Query: 501 APTVAEPSPPVSAPAP-----------AAAPIKTRTRRNKGSRAARGATRKDGLHG-DGP 548
A P P S AP A P R + G + A G+ KDG+ G GP
Sbjct: 710 GDAGA-PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGP 768
Query: 549 -RERATATVPDSSGGGGGGSGASQTGA 574
A P G G A TGA
Sbjct: 769 IGPPGPAGAPGDKGESGPSGPAGPTGA 795
Score = 79.7 bits (195), Expect = 8e-15
Identities = 155/610 (25%), Positives = 189/610 (30%), Gaps = 123/610 (20%)
Query: 52 PGSATPPGLMVPREPQAS-----PSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLP 106
PG PPGL PQ S ST +++ P P+ P S P P P
Sbjct: 147 PGPPGPPGLGGNFAPQLSYGYDEKSTGGISV--PGPMGP--------SGPRGLPGPPGAP 196
Query: 107 GPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKP--PPPPRQLSVKD---TVPRAP 161
GP +Q P G P G+P + P+ P PP P + D P P
Sbjct: 197 GPQGFQGPPGEP---------------GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRP 241
Query: 162 SQFPPP-------LETWKPPPPLPSERQPADRRITPALATPASPPTE----------SQA 204
+ PP L P + R + A PA P E Q
Sbjct: 242 GERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQM 301
Query: 205 GPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAA 264
GPR G R R GAP AG A+ D +G + T + PP ++ A
Sbjct: 302 GPR--GLPGERGRPGAPGPAG----ARGNDGATGAAGPPGPTGPA----GPPGFPGAVGA 351
Query: 265 KASLGGGGGGGLFAASGAISYAEVLKQGPL-PPGAARPLGEVSRGAQEAEGGDGDGEGCS 323
K G G G G + GP P GAA P G Q G G +
Sbjct: 352 KGEAGPQGPRGSEGPQGVRG-----EPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIA 406
Query: 324 GPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAP------- 376
G P P ++ + P P PG K AP G + G G +G
Sbjct: 407 GAPGFPGARGPSGPQGPGGP-PGPKGNSGEPGAP-GSKGDTGAKGEPGPVGVQGPPGPAG 464
Query: 377 ---RRRAAALSGPWGSPPPPPEQ----------IHSAPGPRRPA-----PALLAPPTFIF 418
+R A GP G P PP E+ GP+ PA P P
Sbjct: 465 EEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG 524
Query: 419 PAPTNGEPMRPGPPGLQELPPLP-------------------PPTPPPTLQPPALQPTPL 459
A GE PG GL P P PP PP + P
Sbjct: 525 EAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPG 584
Query: 460 PVAPPLTPGLGHKESALAPTAA--PALPPALAADQAPAPSPAPAPTVAEPSPPVS----- 512
P PG + P A PA A Q P PA E P S
Sbjct: 585 PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQG 644
Query: 513 APAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDG--PRERATATVPDSSGGGGGGSGAS 570
P PA P + +G GA G G+ P ER P +G G
Sbjct: 645 LPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPG 704
Query: 571 QTGAANTRAA 580
GA A
Sbjct: 705 NDGAKGDAGA 714
Score = 73.2 bits (178), Expect = 7e-13
Identities = 128/453 (28%), Positives = 144/453 (31%), Gaps = 106/453 (23%)
Query: 97 PPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPS-LRPLKPPPPPRQLSVKD 155
PP PAG P P +P P +A +G PP P PP P +
Sbjct: 807 PPGPAGFAGP-PGADGQPGAKGEPG-----DAGAKGDAGPPGPAGPAGPPGPIGNVGAPG 860
Query: 156 TVPRAPSQFPP-----PLETWKPPPPLPSERQPADRRITPALATPASPP----TESQAGP 206
S PP P + PP PS A P PP E GP
Sbjct: 861 AKGARGSAGPPGATGFPGAAGRVGPPGPSGN-----------AGPPGPPGPAGKEGGKGP 909
Query: 207 RNQGQTAGRARGGAPPH--AGEGEMAQP-ADSESGLSLLCKITFKSRPSLAPPAASSSLA 263
R + AGR PP GE P AD +G P P +
Sbjct: 910 RGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGA-----------PGTPGPQGIAGQR 958
Query: 264 AKASLGGGGGGGLFAASGAISYAEVLKQGPL-------------PPGAARPLGEVSR-GA 309
L G G F S E KQGP PPG A P GE R GA
Sbjct: 959 GVVGLPGQRGERGFPGLPGPS-GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGA 1017
Query: 310 QEAEGGDG-DGE----------GCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPD 358
AEG G DG G +GPP AP + P P P K + P
Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA-----PGAPGPVGPAGKSGDRGETGPA 1072
Query: 359 GPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQ-------------IHSAPGPRR 405
GP G G +GA R A GP G EQ + PGP
Sbjct: 1073 GPA------GPVGPVGA--RGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124
Query: 406 PAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPL 465
+P P PA G P G PG L LP P PP P PV PP
Sbjct: 1125 -SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPP--GPRGRTGDAGPVGPPG 1181
Query: 466 TPGLGHKESALAPTAAPALPPALAADQAPAPSP 498
PG P P PP+ D + P P
Sbjct: 1182 PPG---------PPGPPG-PPSAGFDFSFLPQP 1204
Score = 57.0 bits (136), Expect = 5e-08
Identities = 79/307 (25%), Positives = 100/307 (32%), Gaps = 41/307 (13%)
Query: 297 GAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSA 356
G P G+ G +G G P P PP P PG F
Sbjct: 109 GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGP----PGLGGNF----- 159
Query: 357 PDGPERHFRFN-GAGGGIGAPRRRAAALSGPWGSPPPP----PEQIHSAPG-PRRP-APA 409
P+ + ++ + GGI P SGP G P PP P+ PG P P A
Sbjct: 160 --APQLSYGYDEKSTGGISVPGPMGP--SGPRGLPGPPGAPGPQGFQGPPGEPGEPGASG 215
Query: 410 LLAPPTFIFPAPTNGE------PMRP---GPPGLQELPPLPPPTPPPTLQP-------PA 453
+ P P NG+ P RP GPPG Q LP P ++
Sbjct: 216 PMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDG 275
Query: 454 LQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPA----PAPTVAEPSP 509
+ P P PG + A LP AP P+ A A A P
Sbjct: 276 AKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPG 335
Query: 510 PVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGD-GPRERATATVPDSSGGGGGGSG 568
P P P + G + RG+ G+ G+ GP A A P + G G G
Sbjct: 336 PTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPG 395
Query: 569 ASQTGAA 575
A A
Sbjct: 396 AKGANGA 402
Score = 40.8 bits (94), Expect = 0.004
Identities = 55/214 (25%), Positives = 66/214 (30%), Gaps = 42/214 (19%)
Query: 386 PWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTP 445
P GS P ++ GP+ P PA G PG PGL PP P
Sbjct: 96 PDGSESPTDQETTGVEGPKGDT----GPRGPRGPAGPPGRDGIPGQPGLP-----GPPGP 146
Query: 446 PPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAP----- 500
P PP L AP L+ G K + P P P +P P
Sbjct: 147 PGPPGPPGLGGN---FAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQG 203
Query: 501 ------APTVAEPSPPVSAPAP---------AAAPIKTRTRRNKGSRAARGATRKDGLHG 545
P + P P P P A P + R G + ARG GL G
Sbjct: 204 PPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPG 263
Query: 546 ----------DGPRERATATVPDSSGGGGGGSGA 569
DG + A P G G +GA
Sbjct: 264 MKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA 297
Score = 30.4 bits (67), Expect = 5.3
Identities = 48/177 (27%), Positives = 58/177 (32%), Gaps = 23/177 (12%)
Query: 52 PGSATPPGLMVPREPQ--ASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPS 109
PG PG R A P P P PV P + P PAG + GP
Sbjct: 1024 PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPV--GPV 1081
Query: 110 KWQKPAGTPVPRIRR--LLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPP 167
+ PAG PR + E RG L+ PP P P +P + P
Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGP---------PGSPGEQGPS 1132
Query: 168 LETWKPPP--PLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPP 222
+ P P S P + L P PP GPR + AG PP
Sbjct: 1133 GASGPAGPRGPPGSAGAPGKDGLN-GLPGPIGPP-----GPRGRTGDAGPVGPPGPP 1183
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 82.4 bits (202), Expect = 1e-15
Identities = 110/413 (26%), Positives = 135/413 (32%), Gaps = 97/413 (23%)
Query: 141 PLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPP-----------------------L 177
P+ PPPPP P P PPPL PPPP L
Sbjct: 2 PVPPPPPP---------PLPPP--PPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALL 50
Query: 178 PSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGA-PPHAGEGEMAQPADSE 236
+Q R + ++P ES G +G + RG + PP G+
Sbjct: 51 ADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGD---------- 100
Query: 237 SGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPP 296
F + PA +A GG G G + + + GPL P
Sbjct: 101 ---------LFAGGFPVLRPAGQRDVA-----GGKTGQGPGSRAPSPRLPNKTISGPLIP 146
Query: 297 GAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSA 356
A+ LG S A + PP P LPPP P S P + +
Sbjct: 147 PASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPP----LPSSSPIKTPLVS 202
Query: 357 PDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTF 416
P GP + AP A PPPPP P P PA L
Sbjct: 203 PPGP-----LTKGNLPVVAPPVPCA--------PPPPPPPPPPTPPPLPPASVLSDKAVK 249
Query: 417 IFPAPTNGEPMRP--------GPPGLQELPPLP------PPTPPPTLQPPA-LQPTPLPV 461
AP + P+ P G PGL+ P P PP PPP L P A P
Sbjct: 250 PQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLP 309
Query: 462 APPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAP 514
APPL PG+ P LPP + QAP A P+PP S P
Sbjct: 310 APPL-PGVNSSSE-----TPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQP 356
Score = 75.9 bits (185), Expect = 1e-13
Identities = 99/370 (26%), Positives = 123/370 (33%), Gaps = 80/370 (21%)
Query: 165 PPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHA 224
PPP PPPPLP P P P++PP + + GR+
Sbjct: 4 PPP-----PPPPLPPPPPPLG---APPPPPPSAPPVSTDTSSLRRADPKGRS-------- 47
Query: 225 GEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAIS 284
A AD + G L R AP SS K GGG AS +
Sbjct: 48 -----ALLADIQQGTRLRKVTQINDRS--APQIESSKGTNKE---GGGSANTRGASTPPT 97
Query: 285 YAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTF 344
++ G P RP G+ A G G G G P +P + + P
Sbjct: 98 LGDLFAGG-FP--VLRPAGQ----RDVAGGKTGQGPGSRAP--SPRLPNKTISGP---LI 145
Query: 345 PGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPR 404
P + P+ S G R PR A P PPPPP P
Sbjct: 146 PPASPRLGNTSEAHGAAR----------TAPPRPNVPAPPPPTPPPPPPPLP------PP 189
Query: 405 RPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPT------- 457
P+ + + P P P + P + PP PP PPP PP L P
Sbjct: 190 LPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP--PPPPPPPPTPPPLPPASVLSDKA 247
Query: 458 -----------PLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAE 506
P+P PL P G+ P + PA A + PAP P P P A
Sbjct: 248 VKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPAS-----PAQDAQEPPAP-PPPLPPYAS 301
Query: 507 PSPPVSAPAP 516
SP S PAP
Sbjct: 302 CSPRASLPAP 311
Score = 56.6 bits (135), Expect = 7e-08
Identities = 84/326 (25%), Positives = 106/326 (32%), Gaps = 74/326 (22%)
Query: 12 GGSRKVQPSDRAPDSR--RTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQAS 69
GG P RAP R ++ P + + RL PP VP P +
Sbjct: 119 GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT 178
Query: 70 PSTLPLTLERP--------SPVMPPPEEAAAVSAP---PPAPAGTLLPGPSKWQKPAGTP 118
P P L P +P++ PP + P PP P P P P P
Sbjct: 179 PPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP--PPPPPPPPPTPPP 236
Query: 119 VPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQ------LSVKDTVPRAPSQFPPPLETWK 172
+P L + + + Q P L P+ PP P L + P +Q PP
Sbjct: 237 LPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPP-----A 291
Query: 173 PPPPLPSERQPADRRITPALATPA------SPPTESQAGPRNQGQTAGRARGGAPPHAGE 226
PPPPLP + R PA P +PP P Q APP
Sbjct: 292 PPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQ----------APPQKA- 340
Query: 227 GEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYA 286
G A PA APP + L K G GGG
Sbjct: 341 GAQALPAPP------------------APPGSQPFLQKKRHGRPGAGGG----------- 371
Query: 287 EVLKQGPLPPGAARPLGEVSRGAQEA 312
L P PP A P E+S +Q+A
Sbjct: 372 -KLNPPPAPP-ARSPTTELSSKSQQA 395
Score = 50.8 bits (120), Expect = 4e-06
Identities = 108/491 (21%), Positives = 147/491 (29%), Gaps = 126/491 (25%)
Query: 68 ASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPV-----PRI 122
++P TL PV+ P + G+ P P K P+ PR+
Sbjct: 93 STPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRL 152
Query: 123 RRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQ 182
EA + PP PPPP P PPPL PPPLPS
Sbjct: 153 GNTSEAHGAARTAPPRPNVPAPPPP------------TPPPPPPPL-----PPPLPS--- 192
Query: 183 PADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLL 242
++P P S GP T G APP P
Sbjct: 193 ----------SSPIKTPLVSPPGP----LTKGNLPVVAPPVPCAPPPPPPPPP------- 231
Query: 243 CKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPL 302
+ P L P + S A K L + + PL P P
Sbjct: 232 -----PTPPPLPPASVLSDKAVKPQL------------APLHLPPIPPPLPLLPPCGYP- 273
Query: 303 GEVSRGAQEAEGGDGDGEGCSGPPSAPASQAR--ALPPPPYTTFPGSKPKFDWVSAPDGP 360
G P++PA A+ PPPP + P+ S P P
Sbjct: 274 ------------------GLKAEPASPAQDAQEPPAPPPPLPPYASCSPR---ASLPAPP 312
Query: 361 ERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPA 420
P +++ + P P P Q AP + A AL AP PA
Sbjct: 313 --------------LPGVNSSSETPPPLPPKSPSFQ---APPQKAGAQALPAP-----PA 350
Query: 421 PTNGEPM-------RPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPG----- 468
P +P RPG G + PP PP PT + + P PG
Sbjct: 351 PPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRN 410
Query: 469 -----LGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKT 523
+ ES + PP P+ P P P + A A +
Sbjct: 411 GSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPGPWLQAEAVGQSSDDI 470
Query: 524 RTRRNKGSRAA 534
+ R ++ ++A+
Sbjct: 471 KGRNSQVTQAS 481
Score = 40.0 bits (92), Expect = 0.007
Identities = 42/165 (25%), Positives = 56/165 (33%), Gaps = 21/165 (12%)
Query: 65 EPQASPSTLPLTLERPSPVMPP---------PEEAAAVSAPPPAPAGTLLPGPSKWQKPA 115
+PQ +P LP + P P++PP P A + PPAP L P S + A
Sbjct: 249 KPQLAPLHLP-PIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPR-A 306
Query: 116 GTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFP---------P 166
P P + + +S PP + PP P P P P
Sbjct: 307 SLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRP 366
Query: 167 PLETWK-PPPPLPSERQPADRRITPALATPASPPTESQAGPRNQG 210
K PPP P R P + + A PT+ G G
Sbjct: 367 GAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNG 411
Score = 36.6 bits (83), Expect = 0.075
Identities = 39/138 (28%), Positives = 50/138 (36%), Gaps = 18/138 (13%)
Query: 439 PLPPPTPPPTLQPP---ALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPA 495
P+PPP PPP PP P P P APP++ +++ A P AL AD
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVS-----TDTSSLRRADPKGRSALLADIQQG 56
Query: 496 PSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGA----TRKDGLHGDGPRER 551
+ + S AP K + GS RGA T D G P R
Sbjct: 57 TRLRKVTQINDRS------APQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLR 110
Query: 552 ATATVPDSSGGGGGGSGA 569
+ G G G G+
Sbjct: 111 PAGQRDVAGGKTGQGPGS 128
Score = 35.4 bits (80), Expect = 0.17
Identities = 37/158 (23%), Positives = 56/158 (35%), Gaps = 21/158 (13%)
Query: 8 PSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQ 67
P G K +P+ A D++ P + A R A+ P +P
Sbjct: 268 PPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPR---------ASLPAPPLPGVNS 318
Query: 68 ASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLE 127
+S + PL + PS PP + A PPAP G+ P +K G P
Sbjct: 319 SSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGS---QPFLQKKRHGRP--------- 366
Query: 128 ASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFP 165
+ G+ +PP P + P + P+Q P
Sbjct: 367 GAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQP 404
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 82.4 bits (202), Expect = 1e-15
Identities = 131/534 (24%), Positives = 180/534 (33%), Gaps = 107/534 (20%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW 111
PG++T ++ P +P+ PS P + + V APPP + LLPG K
Sbjct: 868 PGTSTNGKVLAATAPTPG---IPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPG--KV 922
Query: 112 QKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPP----------PPPRQLSVKDTVPRAP 161
P P S RG G L + PP PP + + + P
Sbjct: 923 LVPLAAP--------SMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTP 974
Query: 162 SQFPPPLETWKPPPPLPSERQ---PADRRIT-------PALATPASPPTESQAGPRNQGQ 211
S PPL P P ++ P+ RIT AL SP + + G
Sbjct: 975 SGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGP 1034
Query: 212 TAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGG 271
T+ A G QP S LL + ++P + A A+ GG
Sbjct: 1035 TSSVALGFTSLGPSGPAFVQPLLSAGQAPLLA----PGQVGVSPVPSPQLPPACAAPGGP 1090
Query: 272 GGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPAS 331
++ S A P ++ PL + S+ PPS +
Sbjct: 1091 VITAFYSGSPA-------------PTSSAPLAQPSQ----------------APPSLVYT 1121
Query: 332 QARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPP 391
A + PP T P P +A P F AG +L P P
Sbjct: 1122 VATSTTPPAATILPKGPPA--PATATPAPTSPFPSATAGS-------MTYSLVAPKAQRP 1172
Query: 392 PPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLP---------- 441
P P++ A+ + P F A +G RPGP Q L P P
Sbjct: 1173 SP-------KAPQKVKAAIASIPVGSFEAGASG---RPGPAPRQPLEPGPVREPTAPESE 1222
Query: 442 ---PPTPPPTLQPPALQPTPLPVA---PPLTPGLGHKESALAPTAAPALPPALAADQAPA 495
PTPP PP L T P A PPL P + SA P + P+ ++D
Sbjct: 1223 LEGQPTPP---APPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWR-V 1278
Query: 496 PSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPR 549
P P+PP APAPA AP + + RAA + G G +
Sbjct: 1279 PGQGLENRGEPPTPPSPAPAPAVAP--GGSSESSSGRAAGDTPERKEAAGTGKK 1330
Score = 75.5 bits (184), Expect = 1e-13
Identities = 149/578 (25%), Positives = 205/578 (35%), Gaps = 120/578 (20%)
Query: 47 LGVWFPGSATPPGLMVPREPQASPSTLPLTLE-RPSPVMPPPEEAAAVSAPPPAPA--GT 103
LG+ PG+ G + + Q TLP L+ P+P P +AAA S P P + T
Sbjct: 808 LGILQPGALGKAGGIT--QVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFT 865
Query: 104 LLPGPSKWQK--PAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAP 161
L PG S K A P P I P L+ + PPP+ SV +P
Sbjct: 866 LPPGTSTNGKVLAATAPTPGI--------------PILQSVPSAPPPKAQSV------SP 905
Query: 162 SQFPPPLETWKPPP---------PLPSERQPADRRITPALATPASPPTESQAGPRNQGQT 212
Q PPP + + P P S R + P ++ P S P ++
Sbjct: 906 VQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQN---------- 955
Query: 213 AGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGG 272
G PP S + L + + L PP + ++L S
Sbjct: 956 -----GAQPP--------------SKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKV 996
Query: 273 GGGLFAASGAISYAEVLKQGPLPPG---AARPLGEV-SRGAQEAEGGDGDGEGCSGP--- 325
L +S I+Y + LP G A+ G V S G + G SGP
Sbjct: 997 ---LLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFV 1053
Query: 326 -PSAPASQARALPPPPYTTFPGSKPKFDWV-SAPDGPERHFRFNGAGGGIGAPRRRAAAL 383
P A QA L P P P+ +AP GP ++G+ AP +A L
Sbjct: 1054 QPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSP----APTS-SAPL 1108
Query: 384 SGPWGSPPP----------PPEQIHSAPGPRRPAPALLAP-PTFIFPAPTNG-------- 424
+ P +PP PP GP PAPA P PT FP+ T G
Sbjct: 1109 AQPSQAPPSLVYTVATSTTPPAATILPKGP--PAPATATPAPTSPFPSATAGSMTYSLVA 1166
Query: 425 -EPMRPGPPGLQELPPLPPPTPPPTLQPPAL-QPTPLPVAPPLTPGLGHKESALAPTAAP 482
+ RP P Q++ P + + A +P P P PL PG P P
Sbjct: 1167 PKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAP-RQPLEPG---------PVREP 1216
Query: 483 ALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKD- 541
P + Q P+P P P P+ S P P A +T + + + ++ D
Sbjct: 1217 TAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDW 1276
Query: 542 GLHGDGPRERATATVPDSSGG----GGGGSGASQTGAA 575
+ G G R P S GGS S +G A
Sbjct: 1277 RVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRA 1314
Score = 63.5 bits (153), Expect = 6e-10
Identities = 123/508 (24%), Positives = 159/508 (31%), Gaps = 124/508 (24%)
Query: 74 PLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQ 133
PL E P P PP + P + A + P+ A T +A GQ
Sbjct: 509 PLDPEPPGPPDPPVAFGKGYGSAPSSSASS----PASSSASAATSFSLGSGTFKAQESGQ 564
Query: 134 GDPPSLRPLKPPP-----PPRQLSVKDTVPRAPSQF-------------PPPLETWKPP- 174
G PL+PPP P +P P+ F P P PP
Sbjct: 565 GSTAG--PLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPS 622
Query: 175 -----------PPLPSERQPADRRI----TPALA--TPASP--------------PTESQ 203
PP E++ R+ P+LA PA+P P S
Sbjct: 623 GGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSST 682
Query: 204 AGP--RNQGQTAGRARGGAPPHAG-EGEMAQPADSESGLSLLCKITFKSRPSLAPPAASS 260
P T+GRA AG EM + G L + + + S A + +
Sbjct: 683 PVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAP 742
Query: 261 SLAAKASLGGGGGGGLFAAS---GAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDG 317
L A LG G + G Y P PP G A G G
Sbjct: 743 HLVAGPLLGTVGKAPATVTNLLVGTPGYG-----APAPPAVQFIAQGAPGGGTTAGSGAG 797
Query: 318 DGEGCSGP------------------------PSAPASQARALPPPPYTTFPGSKPKFDW 353
G G +GP P+ P A P P PG+K
Sbjct: 798 AGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAP---APGTK----- 849
Query: 354 VSAPDG--PERHFRF--------NGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGP 403
+AP G P RF NG AP L +PPP + + P
Sbjct: 850 AAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAP 909
Query: 404 RRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPT---LQPPA--LQPTP 458
A L P + P +R G G Q LP + PP P QPP+ +Q TP
Sbjct: 910 PPGGSAQLLPGKVLVPLAAPSMSVRGGGAG-QPLPLVSPPFSVPVQNGAQPPSKIIQLTP 968
Query: 459 LPVAPPLTPGLGHKESALAPTAAPALPP 486
+PV+ P S L P +PA P
Sbjct: 969 VPVSTP---------SGLVPPLSPATLP 987
Score = 53.5 bits (127), Expect = 6e-07
Identities = 105/442 (23%), Positives = 142/442 (32%), Gaps = 81/442 (18%)
Query: 166 PPLETWKPPPPLPSER-------QPADRRITPALATPASPPTES------QAGPRNQGQT 212
PPL+ P PP P P+ +PA ++ ++ + S +A QG T
Sbjct: 508 PPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGST 567
Query: 213 AGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPS----LAPPAASSSLAAKASL 268
AG R PP G G A P+ + L + + RP L PP S +AA S
Sbjct: 568 AGPLR---PPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSV-IAAPPSG 623
Query: 269 GGG---------------GGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQE-- 311
GG GGG ++ A S A PL AA + V R
Sbjct: 624 GGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTP 683
Query: 312 -------------AEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPD 358
AE D G + P + K +A
Sbjct: 684 VPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKS-----AAAT 738
Query: 359 GPERHFRFNGAGGGIG-APRRRAAALSGP--WGSPPPPPEQI--HSAPG----------- 402
P H G +G AP L G +G+P PP Q APG
Sbjct: 739 SPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGA 798
Query: 403 ---PRRPAPALLAPPTFIFPAP--TNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPT 457
P P P + P + A T + + P P ++ P P P P P+
Sbjct: 799 GSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAP 858
Query: 458 PLPVAPPLTPGLGHKESALAPTA-APALPPALAADQAPAPSPAPAPTVAEPSPPVSA--- 513
+ L PG LA TA P +P + AP P V P P SA
Sbjct: 859 TTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLL 918
Query: 514 PAPAAAPIKTRTRRNKGSRAAR 535
P P+ + +G A +
Sbjct: 919 PGKVLVPLAAPSMSVRGGGAGQ 940
Score = 46.6 bits (109), Expect = 7e-05
Identities = 77/307 (25%), Positives = 99/307 (32%), Gaps = 43/307 (14%)
Query: 252 SLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQE 311
S A ASSS +A S G G SG S A L+ P PPGA
Sbjct: 534 SSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLR--PPPPGA------------- 578
Query: 312 AEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGG 371
G P+ P+ R LP P TF +P+ P GP GG
Sbjct: 579 ------------GGPATPSKATRFLPMDP-ATFRRKRPESVGGLEPPGPSVIAAPPSGGG 625
Query: 372 GIGA-----PRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEP 426
I P + G P P + AP PA + P + P
Sbjct: 626 NILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVP 685
Query: 427 MRPGP---PGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPA 483
+ P G E P + + P P+ L K+SA A + AP
Sbjct: 686 IASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLV--YSDKKSAAATSPAPH 743
Query: 484 LP--PALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKD 541
L P L +PA + +P APAP A + G+ A GA
Sbjct: 744 LVAGPLLGT---VGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGS 800
Query: 542 GLHGDGP 548
G +G P
Sbjct: 801 GPNGPVP 807
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/88 (37%), Positives = 38/88 (43%), Gaps = 10/88 (11%)
Query: 431 PPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAA 490
PPG + PLP P P T PA PTP P P P +S A A P PP +
Sbjct: 1528 PPGAEA--PLPVPPPTGTAAAPA--PTPSPAGGP-DPTSPSSDSGTAQAAPPLPPPPESG 1582
Query: 491 DQAPAPSPAPAPTVAEPSPPVSAPAPAA 518
P AP +PSPP P+ AA
Sbjct: 1583 PGQPGWEGAP-----QPSPPPPGPSTAA 1605
Score = 40.4 bits (93), Expect = 0.005
Identities = 34/100 (34%), Positives = 40/100 (40%), Gaps = 23/100 (23%)
Query: 68 ASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLE 127
A+P+ P E P PV PP AAA AP P+PAG P P+ +GT
Sbjct: 1522 ATPTEQPPGAEAPLPVPPPTGTAAA-PAPTPSPAGG--PDPTSPSSDSGT---------- 1568
Query: 128 ASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPP 167
Q PP PPPP + AP PPP
Sbjct: 1569 ----AQAAPPL------PPPPESGPGQPGWEGAPQPSPPP 1598
Score = 37.0 bits (84), Expect = 0.057
Identities = 39/135 (28%), Positives = 55/135 (40%), Gaps = 12/135 (8%)
Query: 397 IHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGP-PGLQELPPLPPPTPPPTLQPP-AL 454
++SA P PA + + +F TN EP P +P L P P P++QP A
Sbjct: 1 MYSAHRPLMPASSAASRGLGMF-VWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQ 59
Query: 455 QPTPLPVA------PPLTPGLGHKESALAPTAA-PALPPALAADQAPAPSPAPAPTVAE- 506
QP PVA P + + H+ +A P PP ++P P P V E
Sbjct: 60 QPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVES 119
Query: 507 -PSPPVSAPAPAAAP 520
PP + A+ P
Sbjct: 120 GKGPPPTTEEEASGP 134
Score = 37.0 bits (84), Expect = 0.057
Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 3/69 (4%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW 111
PG+ P + P A+P+ P P P P + A +APP P PG W
Sbjct: 1529 PGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGW 1588
Query: 112 QKPAGTPVP 120
+ G P P
Sbjct: 1589 E---GAPQP 1594
Score = 36.2 bits (82), Expect = 0.097
Identities = 29/77 (37%), Positives = 34/77 (44%), Gaps = 14/77 (18%)
Query: 390 PPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTL 449
P PPP +AP P P+PA PT P+ +G Q PPLPPP
Sbjct: 1536 PVPPPTGTAAAPAPT-PSPAGGPDPT--SPSSDSGT--------AQAAPPLPPPPESGPG 1584
Query: 450 QP---PALQPTPLPVAP 463
QP A QP+P P P
Sbjct: 1585 QPGWEGAPQPSPPPPGP 1601
Score = 33.1 bits (74), Expect = 0.83
Identities = 32/93 (34%), Positives = 36/93 (38%), Gaps = 27/93 (29%)
Query: 447 PTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPA--PTV 504
PT QPP + PLPV PP TAA APAP+P+PA P
Sbjct: 1524 PTEQPPGAE-APLPVPPP------------TGTAA-----------APAPTPSPAGGPDP 1559
Query: 505 AEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGA 537
PS S A AA P+ G GA
Sbjct: 1560 TSPSSD-SGTAQAAPPLPPPPESGPGQPGWEGA 1591
Score = 30.8 bits (68), Expect = 4.1
Identities = 23/69 (33%), Positives = 24/69 (34%), Gaps = 8/69 (11%)
Query: 160 APSQFPPPLETWKPPPPLPS------ERQPADRRITPALATPASPPTESQAGPRNQGQTA 213
AP PPP T P P PS P+ T A P PP ES GP G
Sbjct: 1533 APLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPES--GPGQPGWEG 1590
Query: 214 GRARGGAPP 222
PP
Sbjct: 1591 APQPSPPPP 1599
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 81.6 bits (200), Expect = 2e-15
Identities = 74/216 (34%), Positives = 86/216 (39%), Gaps = 28/216 (12%)
Query: 313 EGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKP---KFDWVSAPDGPERHFRFNGA 369
+ G GEG +GPP + A FPG+ P +F + P GP F A
Sbjct: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFP---A 232
Query: 370 GGGIGAPRRRAAALSGPWGSP-PPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMR 428
G P R GP G P PPPP Q+ P P PP +FP G+P
Sbjct: 233 GQ---TPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP----GQPF- 284
Query: 429 PGPPGLQELPPLPPPT-----PPPTLQPPALQPTPLP-VAPPLTPGLGHKESALAPTAAP 482
G P L LPP PPP PPP PP P P P PP PG L P
Sbjct: 285 -GQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPG------PLGPPLTL 337
Query: 483 ALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAA 518
A PP L AP PAP A PP ++ P +
Sbjct: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTS 373
Score = 58.2 bits (139), Expect = 2e-08
Identities = 70/255 (27%), Positives = 86/255 (33%), Gaps = 59/255 (23%)
Query: 51 FPGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPP----------AP 100
FPG A P G P +P P L P P PP PPP P
Sbjct: 217 FPGPAGPGGPPPPFPAGQTPPRPP--LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPP 274
Query: 101 AGTLLPGPSKWQKPAG-------TPVPRIRRLLEASHRGQGDPPSLRPLK--PPPPPRQL 151
L PG Q P G PVP G G PP P + PPPPP
Sbjct: 275 PPVLFPGQPFGQPPLGPLPPGPPPPVP-----------GYGPPPGPPPPQQGPPPPPGPF 323
Query: 152 SVKDTVPRAPSQFPPPLETWKPPPPLPSE---RQPADRRITPALATPASPPTESQAGPRN 208
PR P PPL T PPP LP P + PA P P N
Sbjct: 324 P-----PRPPGPLGPPL-TLAPPPHLPGPPPGAPPPAPHVNPAFFPP----------PTN 367
Query: 209 QGQTAGRARG-------GAPPHAGEGEMAQPA-DSESGLSLLCKITFKSRPSLAPPAASS 260
G +RG G PP G+ P + ++ + L + F+ + +SS
Sbjct: 368 SGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSS 427
Query: 261 SLAAKASLGGGGGGG 275
+++ S G G
Sbjct: 428 AISRAVSDASAGDYG 442
Score = 36.2 bits (82), Expect = 0.097
Identities = 46/160 (28%), Positives = 48/160 (30%), Gaps = 50/160 (31%)
Query: 293 PLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFD 352
P P PLG + G G G PP P Q PPPP FP P
Sbjct: 280 PGQPFGQPPLGPLPPGPPPPVPGYGP------PPGPPPPQQG--PPPPPGPFPPRPP--- 328
Query: 353 WVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLA 412
G +G P A PPP P P P PA
Sbjct: 329 ------------------GPLGPPLTLA-----------PPPHL--PGPPPGAPPPAPHV 357
Query: 413 PPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPP 452
P F FP PTN G PPPT P PP
Sbjct: 358 NPAF-FPPPTNSGMPTSDSRG-------PPPTDPYGRPPP 389
Score = 33.9 bits (76), Expect = 0.48
Identities = 39/150 (26%), Positives = 45/150 (30%), Gaps = 22/150 (14%)
Query: 103 TLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSL--------RPLKPPPPPRQLSVK 154
T G + AG P R RG+G P P P PP
Sbjct: 174 TTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAG 233
Query: 155 DTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPAS------PPTESQAGPRN 208
T PR P P P PPPP + + P LA P + PP P
Sbjct: 234 QTPPRPPLGPPGPPGPPGPPPP--------GQVLPPPLAGPPNRGDRPPPPVLFPGQPFG 285
Query: 209 QGQTAGRARGGAPPHAGEGEMAQPADSESG 238
Q G PP G G P + G
Sbjct: 286 QPPLGPLPPGPPPPVPGYGPPPGPPPPQQG 315
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 81.3 bits (199), Expect = 3e-15
Identities = 126/518 (24%), Positives = 179/518 (34%), Gaps = 89/518 (17%)
Query: 140 RPLKPPPPPRQLSVKDTVPR-----APSQFPPPLETWKPPPPLPSERQPADRRI---TPA 191
R LK PPPR + K +PR A PP E PP + + + D + TP
Sbjct: 710 RELKKKPPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPL 769
Query: 192 LATPASPPTESQAGPRNQGQTAGRARGGAPP--HAGEGEMAQP-ADSESGLSLLCKITFK 248
P+ P+ + GP G PP ++G ++ QP A + +
Sbjct: 770 HFPPSPFPSSTGPGPHYLS-------GPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALY 822
Query: 249 SRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRG 308
P+ P L ++S G + G L P PP + P E++
Sbjct: 823 PAPAYTPELG---LVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAP-PPQFSGP--ELAMA 876
Query: 309 AQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDG-----PERH 363
+ A + +AP PPPP P +P + P G P +H
Sbjct: 877 VRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQH 936
Query: 364 FRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPAL-----------LA 412
+G G APR P P P P Q P++P P L
Sbjct: 937 HFSSGIPAGFPAPRIGPQ----PQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLL 992
Query: 413 PPTFIFP-APTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTP---G 468
PP +P AP G +P PP +L P P P P P+P P PP P G
Sbjct: 993 PPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYG 1052
Query: 469 LGHKESALAPTAAPAL--PPALAADQ------APAPSPAPAPTVAEPSPPVSAPAPAAAP 520
+ P AAP P+ A P+P+P+P P P PP + P P
Sbjct: 1053 PAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPC--- 1109
Query: 521 IKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGG----GGGSGASQTGAAN 576
RGA D L ++ P+S GG GGG Q +
Sbjct: 1110 ------------LRRGAAAADLL----------SSSPESQHGGTQSPGGGQPLLQPTKVD 1147
Query: 577 TRAARHWLPFQVLNSCPCKCYCHHQPRHRRLPRNVSAW 614
R +++ P + H R R+L + + A+
Sbjct: 1148 AAEGRRPQALRLIERDPYE----HPERLRQLQQELEAF 1181
Score = 56.6 bits (135), Expect = 7e-08
Identities = 76/288 (26%), Positives = 98/288 (34%), Gaps = 40/288 (13%)
Query: 76 TLERPSPVMPPPEEAAAVSAPPPA------PAGTLLPGPSKWQ----KPAGTPVPRIRRL 125
T RP+P PP V P P PAG P P++ PAG P PRI
Sbjct: 895 TAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRI--- 951
Query: 126 LEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPP-PPLPSERQPA 184
+ P + P PP + L ++ P FPP PP P P QP
Sbjct: 952 -GPQPQPHPQPHPSQAFGPQPPQQPLPLQH-----PHLFPPQAPGLLPPQSPYPYAPQPG 1005
Query: 185 DRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCK 244
L P PP +Q P G A+ P H+G P + L
Sbjct: 1006 ------VLGQP-PPPLHTQLYP-------GPAQDPLPAHSGALPFPSPGPPQPPHPPLAY 1051
Query: 245 ITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLP--PGAARPL 302
S + P AA ++ +S G S A S GP+P P AA P
Sbjct: 1052 GPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPG----PGPVPPRPPAAEPP 1107
Query: 303 GEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPK 350
+ RGA A+ E G +P L P G +P+
Sbjct: 1108 PCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQ 1155
Score = 35.8 bits (81), Expect = 0.13
Identities = 28/87 (32%), Positives = 33/87 (37%), Gaps = 4/87 (4%)
Query: 408 PALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAP-PLT 466
P L P P P EP P L E P+P +PPP P P P P P
Sbjct: 1510 PGGLESPVASLPGPA--EPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEA 1567
Query: 467 PGLGHKESALAPTAAPALPPALAADQA 493
P G S+L A P A + D +
Sbjct: 1568 PSSGPPSSSL-ELLASLTPEAFSLDSS 1593
Score = 35.8 bits (81), Expect = 0.13
Identities = 31/114 (27%), Positives = 40/114 (35%), Gaps = 22/114 (19%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW 111
PG A PPGL P + P + P+ P P+ P EA PP P PS
Sbjct: 1521 PGPAEPPGL----PPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSS 1576
Query: 112 QKPAGTPVPRIRRLLEA--------------SHRGQGDPPSLRPLKPPPPPRQL 151
+ + P L + +H GQG LR +P P L
Sbjct: 1577 LELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNGQG----LRATRPSDDPLSL 1626
Score = 33.9 bits (76), Expect = 0.48
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 17/64 (26%)
Query: 459 LPVAPPLTPGLGHKESALA----PTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAP 514
L + PP G ES +A P P LPPA + P PS +P PP+S+P
Sbjct: 1505 LSIRPP-----GGLESPVASLPGPAEPPGLPPASLPESTPIPSSSP--------PPLSSP 1551
Query: 515 APAA 518
P A
Sbjct: 1552 LPEA 1555
Score = 33.5 bits (75), Expect = 0.63
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 9/77 (11%)
Query: 431 PPGLQELP--PLPPPTPPPTLQPPAL-------QPTPLPVAPPLTPGLGHKESALAPTAA 481
PPG E P LP P PP L P +L +P P++ PL KE P A
Sbjct: 1509 PPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAP 1568
Query: 482 PALPPALAADQAPAPSP 498
+ PP+ + + + +P
Sbjct: 1569 SSGPPSSSLELLASLTP 1585
Score = 33.1 bits (74), Expect = 0.83
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 16/75 (21%)
Query: 128 ASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRR 187
AS G +PP L P P ++ P PS PPPL + P P P E P
Sbjct: 1518 ASLPGPAEPPGLPPASLP---------ESTP-IPSSSPPPLSSPLPEAPQPKEEPPVPE- 1566
Query: 188 ITPALATPASPPTES 202
A + PP+ S
Sbjct: 1567 -----APSSGPPSSS 1576
Score = 30.8 bits (68), Expect = 4.1
Identities = 27/103 (26%), Positives = 33/103 (32%), Gaps = 19/103 (18%)
Query: 51 FPGSATPP------GLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTL 104
+PG A P L P P PL P +AA ++ P+ AG
Sbjct: 1019 YPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQS 1078
Query: 105 LPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPP 147
P P PA +P G G P P PPP
Sbjct: 1079 TPSPHLVPSPAPSP-------------GPGPVPPRPPAAEPPP 1108
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 80.9 bits (198), Expect = 3e-15
Identities = 144/562 (25%), Positives = 189/562 (33%), Gaps = 92/562 (16%)
Query: 5 QSEPS-AGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVP 63
QS+P+ AG + V P S L P+ Q G P P P
Sbjct: 569 QSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPA---P 625
Query: 64 REPQASPSTLPLTLERPSPVMPP----PEEAAAVSAPPPAPAGTLLPGPSK---WQKPAG 116
+ P A + LPL L++P PP P+ AA A P P+ L P K Q P+
Sbjct: 626 QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSA 685
Query: 117 TPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPP 176
TP + + ++ S +PL P LSV +V + PPP + P P
Sbjct: 686 TPTAILTQ--DSLQMFLPQERSQQPLSAEGP--HLSVPASVIVSA---PPPAQDPAPATP 738
Query: 177 LPSER----QPADRRITPALA--TPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMA 230
+ Q D + +PA A PA+ P + GP + +A G PH
Sbjct: 739 VAKGAGLGPQAPDSQASPAPAPQIPAAAPLKG-PGPSSSPSLPHQAPLGDSPHLPSPHPT 797
Query: 231 QPADSESGLSLLCKITFKSRPSLAPPA-ASSSLAAKASLGGGGGGGLFAASGAISYAEVL 289
+P + SRP PP A +L G+F +
Sbjct: 798 RPPSRPPS-----RPQSVSRPPSEPPLHPCPPPQAPPTL-----PGIFV---------IQ 838
Query: 290 KQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKP 349
Q +PP A+ P G PP P SQ P PP P S
Sbjct: 839 NQLGVPPPASNPA--------------PTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSST 884
Query: 350 KFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAAL-----SGPWGSPPPPPEQIHSAPGPR 404
S+ + R + AP L GP SP PPP +H P P
Sbjct: 885 SSAVASSSETSSR----------LPAPTPSDFQLQFPPSQGPHKSPTPPP-TLHLVPEPA 933
Query: 405 RPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPP---TPPPTLQPPALQPTPLPV 461
P P PP F T P P P L E P PA T +
Sbjct: 934 APPP----PPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSL 989
Query: 462 APPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPI 521
P +P S AP+ P AP+ +PAPAP A PP+ PA A
Sbjct: 990 GPLTSPAASVLVSGQAPSGTPT---------APSHAPAPAPMAATGLPPL-LPAENKAFA 1039
Query: 522 KTRTRRNKGSRAARGATRKDGL 543
N A+ G + GL
Sbjct: 1040 SNLPTLNVAKAASSGPGKPSGL 1061
Score = 78.6 bits (192), Expect = 2e-14
Identities = 129/470 (27%), Positives = 161/470 (34%), Gaps = 98/470 (20%)
Query: 71 STLPLTLERPSPVMPPPEEAAAVSAPP---PAPAGTLLPGPSKWQKPAGTPVPRIRRLLE 127
S P+ + +P+ + P AA S P PAPAG PA T V +
Sbjct: 543 SAAPIQVGQPA-LFQMPVSLAAGSLPTQSQPAPAG-----------PAATTVLQ------ 584
Query: 128 ASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRR 187
G PPS + P V+ P A + P+ T +P P P
Sbjct: 585 ----GVTLPPSAVAMLNTPDGL---VQPATPAAATGEAAPVLTVQPAPQAP--------- 628
Query: 188 ITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITF 247
PA++TP P Q Q A + APP A P S S KI
Sbjct: 629 --PAVSTPL--PLGLQQPQAQQPPQAPTPQAAAPPQA-----TTPQPSPGLASSPEKIVL 679
Query: 248 KSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGA-ISY-AEVLKQGPLPPGAARPLGEV 305
PS P A + + + L +A G +S A V+ P P P V
Sbjct: 680 GQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV 739
Query: 306 SRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTF-------PGSKPKFDWVSAPD 358
++GA G G P AP SQA P P P S P AP
Sbjct: 740 AKGA---------GLG----PQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH-QAPL 785
Query: 359 GPERHFRFNGAGGGIGAPRRRAAALSGPWGSPP----PPPEQIHSAPGPRRPAPALLAPP 414
G H P R ++S P PP PPP+ + PG L PP
Sbjct: 786 GDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP 845
Query: 415 TFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKES 474
PAPT PGPP PPL P + PP PLP AP L P
Sbjct: 846 PASNPAPT-----APGPPQ----PPLRPQSQPPE--------GPLPPAPHLPPSSTSSAV 888
Query: 475 ALAPTAAPALPPALAAD--------QAPAPSPAPAPTVAEPSPPVSAPAP 516
A + + LP +D Q P SP P PT+ P + P P
Sbjct: 889 ASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPP 938
Score = 51.2 bits (121), Expect = 3e-06
Identities = 70/283 (24%), Positives = 93/283 (32%), Gaps = 38/283 (13%)
Query: 306 SRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTF-------PGSKPKFDWVSAPD 358
S G A +G GP S+ A A PPP T G P W A
Sbjct: 1207 SLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASS 1266
Query: 359 GPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPG--------PRRPAPAL 410
+ A + A GP S PP + + A + +
Sbjct: 1267 SLSSSSSSSSAASSLDADE------DGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSK 1320
Query: 411 LAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAP------- 463
+ T + P + P P + E PP PPP PPPT Q P P AP
Sbjct: 1321 VVHNTAL--DPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGT 1378
Query: 464 -PLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIK 522
P P L +++ P P A +A SPAP P + + AA +
Sbjct: 1379 APHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDE 1438
Query: 523 TRTRRNKG------SRAARGATRKD-GLHGDGPRERATATVPD 558
R KG + AA+G D G P +R + PD
Sbjct: 1439 LYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPD 1481
Score = 47.4 bits (111), Expect = 4e-05
Identities = 69/275 (25%), Positives = 88/275 (32%), Gaps = 63/275 (22%)
Query: 143 KPPPPPRQLSVKDTVPRAPSQFPPPLE---TWKPPPPLPSERQPADRRITPALATPASPP 199
+PPPPP L V + PR P PP + T PPP ER+P
Sbjct: 1332 QPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTY 1391
Query: 200 TESQAGP-RNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAA 258
E+ GP +G AGRARGG+P
Sbjct: 1392 RENVGGPGAPEGTPAGRARGGSP------------------------------------- 1414
Query: 259 SSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGD 318
+ L AK G AA Y +LK P P A+ G GD D
Sbjct: 1415 -APLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGT----------GDPD 1463
Query: 319 GEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVS--APDGPERHFRFNGAGGGIGAP 376
E PP+ + P +F P+ D ++ + A G AP
Sbjct: 1464 WEAPGLPPA--KRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAP 1521
Query: 377 RRRAAALSGPWGSPPP-------PPEQIHSAPGPR 404
AA +G SPPP PP + G R
Sbjct: 1522 SYPHAASAGTPASPPPLHRPEAYPPSSHNGGLGAR 1556
Score = 43.1 bits (100), Expect = 8e-04
Identities = 60/226 (26%), Positives = 74/226 (32%), Gaps = 27/226 (11%)
Query: 325 PPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERH-FRFNGAGGGI--GAPRRRAA 381
PP P Q P P KP P P R +R N G G G P RA
Sbjct: 1351 PPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRAR 1410
Query: 382 ALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQ------ 435
GSP P P ++ A L A ++ G P P Q
Sbjct: 1411 G-----GSPAPLPAKVDEATSGL--IRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPD 1463
Query: 436 -ELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAP 494
E P LPP + P Q + +P ++ L A+ L QAP
Sbjct: 1464 WEAPGLPPAKRRKSESPDVDQASFSSDSP--------QDDTLTEHLQSAIDSILNLQQAP 1515
Query: 495 APSPAPA-PTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATR 539
+PAP+ P A P S P P P + G AR TR
Sbjct: 1516 GRTPAPSYPHAASAGTPAS-PPPLHRPEAYPPSSHNGGLGARTLTR 1560
Score = 37.4 bits (85), Expect = 0.044
Identities = 53/199 (26%), Positives = 72/199 (36%), Gaps = 17/199 (8%)
Query: 385 GPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPP- 443
GP+ P P + P A A+ A P +FP T+ ++ GPP + L PP
Sbjct: 127 GPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQ-GPPTVLTHQALVPPQ 185
Query: 444 -------TPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAP 496
+ P LQP L L P L GL + A A L P Q
Sbjct: 186 DVVNKALSVQPFLQPVGLGNVTLQPIPGL-QGLPNGSPGGATAATLGLAPIQVVGQPVMA 244
Query: 497 SPAPAPTVAEPSPPVSA-PAPAAAPIKTRTRRNKG-SRAARGATRKDGLHGDGPRERATA 554
P + PVS A AA P + T + G S G + L
Sbjct: 245 LNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSA-----AVAT 299
Query: 555 TVPDSSGGGGGGSGASQTG 573
T+ +S GG G+ ++ TG
Sbjct: 300 TLNGNSVFGGAGAASAPTG 318
Score = 35.4 bits (80), Expect = 0.17
Identities = 48/157 (30%), Positives = 58/157 (36%), Gaps = 23/157 (14%)
Query: 366 FNGAGGG---IGAPRRRAAALSGPWGSPP--PPPEQI-HSAPGPRRPAPALLAPPTFIFP 419
F GAG G P + A++ GS P P P I H P P +P PA + PP
Sbjct: 307 FGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQL 366
Query: 420 APTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPT 479
P +P P L P P QP A Q A G + L+
Sbjct: 367 TP------KPFAPAGATLTIQGEPGALPQ-QPKAPQNLTFMAA-----GKAGQNVVLSGF 414
Query: 480 AAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAP 516
APAL A Q PA + AP P PP + P
Sbjct: 415 PAPAL-QANVFKQPPATTTGAAP----PQPPGALSKP 446
Score = 30.8 bits (68), Expect = 4.1
Identities = 50/214 (23%), Positives = 73/214 (34%), Gaps = 56/214 (26%)
Query: 65 EPQASPSTLPLTLERPSPVMPPP---EEAAAVSAPPPA-----PAGTL-----LPGPSKW 111
+P P+TL + P P PPP + V PPPA P GT LP +
Sbjct: 1332 QPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTY 1391
Query: 112 QK-------PAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQL-----SVKDTVPR 159
++ P GTP R R G P+ P K L +V+D + +
Sbjct: 1392 RENVGGPGAPEGTPAGRAR----------GGSPAPLPAKVDEATSGLIRELAAVEDELYQ 1441
Query: 160 APSQFPPPLET-----------WKPPPPLPSERQPADRRITPALATPASPPTESQAGPR- 207
+ PPP W+ P P++R+ ++ + + P +
Sbjct: 1442 RMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHL 1501
Query: 208 --------NQGQTAGRARGGAPPHAGE-GEMAQP 232
N Q GR + PHA G A P
Sbjct: 1502 QSAIDSILNLQQAPGRTPAPSYPHAASAGTPASP 1535
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 80.9 bits (198), Expect = 3e-15
Identities = 107/419 (25%), Positives = 138/419 (32%), Gaps = 82/419 (19%)
Query: 173 PPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQP 232
PPPP P P PPT QA + RG G + Q
Sbjct: 6 PPPPPPG---------------PPPPPTFHQANTEQPKLSRDEQRG-------RGALLQD 43
Query: 233 ADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQG 292
+ L + I +S P L P SS G G GG G + VLK
Sbjct: 44 ICKGTKLKKVTNINDRSAPILEKPKGSSG-------GYGSGGAALQPKGGLFQGGVLKLR 96
Query: 293 PLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFD 352
P+ G E +G P+ +RA P P + +P+ D
Sbjct: 97 PV-------------------GAKDGSENLAGKPALQIPSSRAAAPRPPVSAASGRPQDD 137
Query: 353 WVSAPDG-PERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALL 411
S+ PE + + P ++ S PPPP A P P P
Sbjct: 138 TDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHS 197
Query: 412 APPTFIFPAPTNGEPMRPGP-----PGLQELPPLPPPTPPPTL--------QPPALQPTP 458
+ PA +P+ P P PG +E PP PPP PP +L P P
Sbjct: 198 SKA----PAYNREKPLPPTPGQRLHPG-REGPPAPPPVKPPPSPVNIRTGPSGQSLAPPP 252
Query: 459 LPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPA-----PAPTVAEPS----- 508
P P PG+ + S+ +AP LP + P P P PT A PS
Sbjct: 253 PPYRQP--PGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNR 310
Query: 509 PPVSA---PAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGG 564
PP A P+ AAP G+R A +HG P R P S G
Sbjct: 311 PPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAG 369
Score = 59.3 bits (142), Expect = 1e-08
Identities = 90/312 (28%), Positives = 117/312 (37%), Gaps = 59/312 (18%)
Query: 196 ASPPTESQAGPRNQGQTAGRARGGAPP-HAGEGEMAQPADSE-SGLSLLCKITFKSRPSL 253
A +E+ AG + RA PP A G DS + L L ++ S P L
Sbjct: 100 AKDGSENLAGKPALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDL 159
Query: 254 APPAASSSLAAKASLGG------GGGGGL------FAASGAISYAEVLKQGPLPPGAARP 301
+ P +SS K S G +S A +Y ++ PLPP +
Sbjct: 160 SRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYN---REKPLPPTPGQR 216
Query: 302 LGEVSRGAQEAEGGDGDGEGCSGPPS------APASQARALPPPPYTTFPG-----SKPK 350
L G PPS P+ Q+ A PPPPY PG S P
Sbjct: 217 L-------HPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPT 269
Query: 351 FDWVSAPDGPERHFRFN----GAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRP 406
+ SAP+ P+RH + G G+ P +A+ S PPPP P R
Sbjct: 270 NE--SAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARD----PPSRGA 323
Query: 407 APALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPT----PPPTLQPPALQPTPLPVA 462
AP PP P NG P PP + PP+ PPP + PA P P P
Sbjct: 324 APP---PPP---PVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPP-- 375
Query: 463 PPLTPGLGHKES 474
PPL GH++S
Sbjct: 376 PPLRN--GHRDS 385
Score = 58.9 bits (141), Expect = 1e-08
Identities = 92/353 (26%), Positives = 116/353 (32%), Gaps = 73/353 (20%)
Query: 57 PPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAG 116
P G E A L + R + PP A+ + LP + Q+P+
Sbjct: 97 PVGAKDGSENLAGKPALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPS- 155
Query: 117 TPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPP 176
+P + R S G S P PPPP R+ + T S P KP PP
Sbjct: 156 --LPDLSRPNTTSSTGMKHSSSAPP--PPPPGRRANAPPTPLPMHSSKAPAYNREKPLPP 211
Query: 177 LPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSE 236
P +R R PA PP + P N +T + APP QP
Sbjct: 212 TPGQRLHPGRE-----GPPAPPPVKPPPSPVNI-RTGPSGQSLAPP---PPPYRQPPGVP 262
Query: 237 SGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPP 296
+G S T +S P L P +SL K G GL + +L P PP
Sbjct: 263 NGPS---SPTNESAPEL--PQRHNSLHRKTP---GPVRGLAPPPPTSASPSLLSNRPPPP 314
Query: 297 GAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQAR-ALPPPPYTTFPGSKPKFDWVS 355
P SRGA PP + AR A PPPP GS+P
Sbjct: 315 ARDPP----SRGAAPPP-----------PPPVIRNGARDAPPPPPPYRMHGSEP------ 353
Query: 356 APDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAP 408
P R G PPPPP + + P P P P
Sbjct: 354 ----PSR-------------------------GKPPPPPSRTPAGPPPPPPPP 377
Score = 41.6 bits (96), Expect = 0.002
Identities = 57/193 (29%), Positives = 72/193 (37%), Gaps = 45/193 (23%)
Query: 53 GSATPPGLMVPREPQASPSTLPLTLERPSPVM---PPPEEAAA---VSAPPPAPAGTLLP 106
G ++P P PQ S L + P PV PPP +A+ +S PP PA
Sbjct: 264 GPSSPTNESAPELPQRHNS---LHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPA---RD 317
Query: 107 GPSKWQKPAGTPVPRIRRLLEAS------HRGQGDPPSLRPLKPPPPPRQLSVKDTVPRA 160
PS+ P P P IR + +R G P R KPPPPP R
Sbjct: 318 PPSRGAAPP-PPPPVIRNGARDAPPPPPPYRMHGSEPPSRG-KPPPPP---------SRT 366
Query: 161 PSQFPPPLETWKPPPPLPSERQPADRRITPALATPAS-----------PPTESQAGPRNQ 209
P+ PPP PPPPL + + + + L S P E + R
Sbjct: 367 PAGPPPP-----PPPPLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHFQRIY 421
Query: 210 GQTAGRARGGAPP 222
RA GAPP
Sbjct: 422 PSKTNRAARGAPP 434
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 80.5 bits (197), Expect = 5e-15
Identities = 130/517 (25%), Positives = 165/517 (31%), Gaps = 103/517 (19%)
Query: 54 SATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPP---APAGTLLPGPSK 110
SA+PPGL P PS P + + +PP E AP P PA + P P
Sbjct: 314 SASPPGLGAQPLPGHLPS--PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPM 371
Query: 111 ---WQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPP---PPPRQLSVKDTVPRAPSQF 164
+ + + +S P S P PPP LSV + P+
Sbjct: 372 RFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPS 431
Query: 165 PPPLETWK--PPPPLPSERQPADRRITPALATP-------ASPPT-------------ES 202
P W PPPP P R A+ P P A PP +
Sbjct: 432 LPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQ 491
Query: 203 QAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSL 262
Q + Q Q G PP A P E G S A P A S
Sbjct: 492 QQQQQQQQQQQHHGNSGPPPPG-----AFPHPLEGGSS-----------HHAHPYAMSPS 535
Query: 263 AAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGC 322
G L +SY++ GP ++ S+G+ C
Sbjct: 536 LGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP----------C 585
Query: 323 SGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAA 382
S P + Q P PP T S V A
Sbjct: 586 SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIA------------------------TV 621
Query: 383 LSGPWG----SPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPG-PPGLQEL 437
S P G SPP PP AP P A PP + P + R G PPG +
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTA--TPPGY---KPGSPPSFRTGTPPGYRGT 676
Query: 438 PPLPPPTPPPTLQP--PALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPA 495
P P P T +P P + P PLP A P GL S P AAPA P L+A Q
Sbjct: 677 SP---PAGPGTFKPGSPTVGPGPLPPAGP--SGL---PSLPPPPAAPASGPPLSATQIKQ 728
Query: 496 PSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSR 532
T P PP +P+P + + ++ +R
Sbjct: 729 EPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSAR 765
Score = 77.0 bits (188), Expect = 5e-14
Identities = 144/594 (24%), Positives = 179/594 (30%), Gaps = 142/594 (23%)
Query: 51 FPGSATPPGLMVPREPQAS----PSTLPLTLERPSPVMPPPEEA---AAVSAPPPAP--- 100
FP S PP PR+P+AS PS P P M PP A APPP P
Sbjct: 165 FPPSPQPPD-STPRQPEASFEPHPSVTPTGYHAP---MEPPTSRMFQAPPGAPPPHPQLY 220
Query: 101 ---AGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLK----------PPPP 147
G +L GP K G + + G+ PP P+ P P
Sbjct: 221 PGGTGGVLSGPPMGPKGGGAASS-----VGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275
Query: 148 PRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPR 207
P +P AP P T PPP PA R + A A+P + G
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLPPP------PALRPLNNASASPPGLGAQPLPGHL 329
Query: 208 NQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKAS 267
G+ GG PP +G P+ P PPA+SS+ A
Sbjct: 330 PSPHAMGQGMGGLPPGPEKGPTLAPS-----------------PHSLPPASSSAPAPPMR 372
Query: 268 LGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPS 327
AA+ + S + P P A P S PP
Sbjct: 373 FPYSSSSSSSAAASSSSSSSSSSASPFPASQALP-----------------SYPHSFPP- 414
Query: 328 APASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRF---NGAGGGIGAPRRRAAALS 384
P S + + PP YT P + W P P + R + A G P A + +
Sbjct: 415 -PTSLSVSNQPPKYTQ-PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472
Query: 385 GPWGS------------------PPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNG-- 424
P S +Q H GP PP FP P G
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP---------PPPGAFPHPLEGGS 523
Query: 425 ------EPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPG---------- 468
M P L+ PP P PPP Q Q P PP++
Sbjct: 524 SHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAG--PNGPPVSSSSNSSSSTSQG 581
Query: 469 ---LGHKESALAPTAAP-ALPPALAADQAP----------APSPAPAPTVAEPSPP---V 511
H + P AP PP + A SPA T + P PP
Sbjct: 582 SYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK 641
Query: 512 SAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGG 565
AP+P A T GS + G G P P S G G
Sbjct: 642 RAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPG 695
Score = 58.5 bits (140), Expect = 2e-08
Identities = 92/353 (26%), Positives = 119/353 (33%), Gaps = 73/353 (20%)
Query: 165 PPPLETWKPPPPLPSERQP-----ADRRITPA--------------LATPASPPTESQAG 205
PPPL P PP + RQP +TP A P +PP Q
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLY 220
Query: 206 PRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAA- 264
P G T G G G G + G K P P + SS A
Sbjct: 221 P---GGTGGVLSGPPMGPKGGGAASSVGGPNGG---------KQHPPPTTPISVSSSGAS 268
Query: 265 -----KASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSR-----GAQEAEG 314
K GGG L +A ++ V P PP A RPL S GAQ G
Sbjct: 269 GAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLP-PPPALRPLNNASASPPGLGAQPLPG 327
Query: 315 ----GDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAG 370
G+G G P P + L P P++ P S SAP P R F ++ +
Sbjct: 328 HLPSPHAMGQGMGGLPPGP-EKGPTLAPSPHSLPPASS------SAPAPPMR-FPYSSSS 379
Query: 371 GGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLA---PPTFIFPAPTNGEPM 427
A +++ S SP P + + S P P +L PP + P+ +
Sbjct: 380 SSSAAASSSSSSSSSS-ASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVW 438
Query: 428 RPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTA 480
GPP PPP L P P P P G + +A P +
Sbjct: 439 SQGPP--------PPPPYGRLLANSNAHPGPFP------PSTGAQSTAHPPVS 477
Score = 51.6 bits (122), Expect = 2e-06
Identities = 71/244 (29%), Positives = 88/244 (36%), Gaps = 57/244 (23%)
Query: 316 DGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGA--GGGI 373
+ D + SG PA R PPP FP S D S P PE F + + G
Sbjct: 142 ENDSDSSSGLSQGPA---RPYHPPPL--FPPSPQPPD--STPRQPEASFEPHPSVTPTGY 194
Query: 374 GAPRRRAAA--LSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGP 431
AP + P G+PPP P+ G L PP + P GP
Sbjct: 195 HAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGG-----VLSGPP--MGPKGGGAASSVGGP 247
Query: 432 PGLQELPPLPPPTPPPTLQ-------PPALQPTP------LPVAPP------LTPGLGHK 472
G ++ PP PT P ++ PP PT LP APP +TP L
Sbjct: 248 NGGKQHPP---PTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPP 304
Query: 473 ESALAPTAAPALPPALAADQAPA----------------PSPAPAPTVAEPSPPVSAPAP 516
+ A A PP L A P P P PT+A PSP PA
Sbjct: 305 PALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA-PSPHSLPPAS 363
Query: 517 AAAP 520
++AP
Sbjct: 364 SSAP 367
Score = 32.3 bits (72), Expect = 1.4
Identities = 25/88 (28%), Positives = 34/88 (38%), Gaps = 19/88 (21%)
Query: 391 PPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGE-PMRPGPPGLQELPPLPPPTPPPTL 449
P E +H PGP + P P +G ++PGPPGL P P+L
Sbjct: 954 PSELEPLHGVPGPG------------LDPFPRHGGLALQPGPPGLHPFP------FHPSL 995
Query: 450 QPPALQPTPLPVAPPLTPGLGHKESALA 477
P + L P L P + + E A
Sbjct: 996 GPLERERLALAAGPALRPDMSYAERLAA 1023
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 80.5 bits (197), Expect = 5e-15
Identities = 130/517 (25%), Positives = 165/517 (31%), Gaps = 103/517 (19%)
Query: 54 SATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPP---APAGTLLPGPSK 110
SA+PPGL P PS P + + +PP E AP P PA + P P
Sbjct: 314 SASPPGLGAQPLPGHLPS--PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPM 371
Query: 111 ---WQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPP---PPPRQLSVKDTVPRAPSQF 164
+ + + +S P S P PPP LSV + P+
Sbjct: 372 RFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPS 431
Query: 165 PPPLETWK--PPPPLPSERQPADRRITPALATP-------ASPPT-------------ES 202
P W PPPP P R A+ P P A PP +
Sbjct: 432 LPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQ 491
Query: 203 QAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSL 262
Q + Q Q G PP A P E G S A P A S
Sbjct: 492 QQQQQQQQQQQHHGNSGPPPPG-----AFPHPLEGGSS-----------HHAHPYAMSPS 535
Query: 263 AAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGC 322
G L +SY++ GP ++ S+G+ C
Sbjct: 536 LGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP----------C 585
Query: 323 SGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAA 382
S P + Q P PP T S V A
Sbjct: 586 SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIA------------------------TV 621
Query: 383 LSGPWG----SPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPG-PPGLQEL 437
S P G SPP PP AP P A PP + P + R G PPG +
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTA--TPPGY---KPGSPPSFRTGTPPGYRGT 676
Query: 438 PPLPPPTPPPTLQP--PALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPA 495
P P P T +P P + P PLP A P GL S P AAPA P L+A Q
Sbjct: 677 SP---PAGPGTFKPGSPTVGPGPLPPAGP--SGL---PSLPPPPAAPASGPPLSATQIKQ 728
Query: 496 PSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSR 532
T P PP +P+P + + ++ +R
Sbjct: 729 EPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSAR 765
Score = 77.0 bits (188), Expect = 5e-14
Identities = 144/594 (24%), Positives = 179/594 (30%), Gaps = 142/594 (23%)
Query: 51 FPGSATPPGLMVPREPQAS----PSTLPLTLERPSPVMPPPEEA---AAVSAPPPAP--- 100
FP S PP PR+P+AS PS P P M PP A APPP P
Sbjct: 165 FPPSPQPPD-STPRQPEASFEPHPSVTPTGYHAP---MEPPTSRMFQAPPGAPPPHPQLY 220
Query: 101 ---AGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLK----------PPPP 147
G +L GP K G + + G+ PP P+ P P
Sbjct: 221 PGGTGGVLSGPPMGPKGGGAASS-----VGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275
Query: 148 PRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPR 207
P +P AP P T PPP PA R + A A+P + G
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLPPP------PALRPLNNASASPPGLGAQPLPGHL 329
Query: 208 NQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKAS 267
G+ GG PP +G P+ P PPA+SS+ A
Sbjct: 330 PSPHAMGQGMGGLPPGPEKGPTLAPS-----------------PHSLPPASSSAPAPPMR 372
Query: 268 LGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPS 327
AA+ + S + P P A P S PP
Sbjct: 373 FPYSSSSSSSAAASSSSSSSSSSASPFPASQALP-----------------SYPHSFPP- 414
Query: 328 APASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRF---NGAGGGIGAPRRRAAALS 384
P S + + PP YT P + W P P + R + A G P A + +
Sbjct: 415 -PTSLSVSNQPPKYTQ-PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472
Query: 385 GPWGS------------------PPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNG-- 424
P S +Q H GP PP FP P G
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP---------PPPGAFPHPLEGGS 523
Query: 425 ------EPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPG---------- 468
M P L+ PP P PPP Q Q P PP++
Sbjct: 524 SHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAG--PNGPPVSSSSNSSSSTSQG 581
Query: 469 ---LGHKESALAPTAAP-ALPPALAADQAP----------APSPAPAPTVAEPSPP---V 511
H + P AP PP + A SPA T + P PP
Sbjct: 582 SYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK 641
Query: 512 SAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGG 565
AP+P A T GS + G G P P S G G
Sbjct: 642 RAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPG 695
Score = 58.5 bits (140), Expect = 2e-08
Identities = 92/353 (26%), Positives = 119/353 (33%), Gaps = 73/353 (20%)
Query: 165 PPPLETWKPPPPLPSERQP-----ADRRITPA--------------LATPASPPTESQAG 205
PPPL P PP + RQP +TP A P +PP Q
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLY 220
Query: 206 PRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAA- 264
P G T G G G G + G K P P + SS A
Sbjct: 221 P---GGTGGVLSGPPMGPKGGGAASSVGGPNGG---------KQHPPPTTPISVSSSGAS 268
Query: 265 -----KASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSR-----GAQEAEG 314
K GGG L +A ++ V P PP A RPL S GAQ G
Sbjct: 269 GAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLP-PPPALRPLNNASASPPGLGAQPLPG 327
Query: 315 ----GDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAG 370
G+G G P P + L P P++ P S SAP P R F ++ +
Sbjct: 328 HLPSPHAMGQGMGGLPPGP-EKGPTLAPSPHSLPPASS------SAPAPPMR-FPYSSSS 379
Query: 371 GGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLA---PPTFIFPAPTNGEPM 427
A +++ S SP P + + S P P +L PP + P+ +
Sbjct: 380 SSSAAASSSSSSSSSS-ASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVW 438
Query: 428 RPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTA 480
GPP PPP L P P P P G + +A P +
Sbjct: 439 SQGPP--------PPPPYGRLLANSNAHPGPFP------PSTGAQSTAHPPVS 477
Score = 51.6 bits (122), Expect = 2e-06
Identities = 71/244 (29%), Positives = 88/244 (36%), Gaps = 57/244 (23%)
Query: 316 DGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGA--GGGI 373
+ D + SG PA R PPP FP S D S P PE F + + G
Sbjct: 142 ENDSDSSSGLSQGPA---RPYHPPPL--FPPSPQPPD--STPRQPEASFEPHPSVTPTGY 194
Query: 374 GAPRRRAAA--LSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGP 431
AP + P G+PPP P+ G L PP + P GP
Sbjct: 195 HAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGG-----VLSGPP--MGPKGGGAASSVGGP 247
Query: 432 PGLQELPPLPPPTPPPTLQ-------PPALQPTP------LPVAPP------LTPGLGHK 472
G ++ PP PT P ++ PP PT LP APP +TP L
Sbjct: 248 NGGKQHPP---PTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPP 304
Query: 473 ESALAPTAAPALPPALAADQAPA----------------PSPAPAPTVAEPSPPVSAPAP 516
+ A A PP L A P P P PT+A PSP PA
Sbjct: 305 PALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA-PSPHSLPPAS 363
Query: 517 AAAP 520
++AP
Sbjct: 364 SSAP 367
Score = 32.3 bits (72), Expect = 1.4
Identities = 25/88 (28%), Positives = 34/88 (38%), Gaps = 19/88 (21%)
Query: 391 PPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGE-PMRPGPPGLQELPPLPPPTPPPTL 449
P E +H PGP + P P +G ++PGPPGL P P+L
Sbjct: 954 PSELEPLHGVPGPG------------LDPFPRHGGLALQPGPPGLHPFP------FHPSL 995
Query: 450 QPPALQPTPLPVAPPLTPGLGHKESALA 477
P + L P L P + + E A
Sbjct: 996 GPLERERLALAAGPALRPDMSYAERLAA 1023
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 79.3 bits (194), Expect = 1e-14
Identities = 128/509 (25%), Positives = 165/509 (32%), Gaps = 73/509 (14%)
Query: 80 PSPVMPPPEEAAAVSAPP------PAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQ 133
P P P E A +A P P P G PGP+ + G P+ A G
Sbjct: 1083 PGPAGSPGERGPAGAAGPIGIPGRPGPQGP--PGPAGEKGAPGEKGPQG----PAGRDGL 1136
Query: 134 GDPPSLR-PLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPAL 192
P L P P PP + K + P Q + + PP P+ Q +
Sbjct: 1137 QGPVGLPGPAGPVGPPGEDGDKGEIGE-PGQKGSKGDKGEQGPPGPTGPQGP-------I 1188
Query: 193 ATPASPPTESQAGPRNQ-------GQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKI 245
P + + GPR Q G R G P G + P + + ++
Sbjct: 1189 GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM 1248
Query: 246 TFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQG-PLPPGAARPLGE 304
P P S + A G GG G A G E + G P PG P G
Sbjct: 1249 GPPGPPG--PRGPSGAPGADGPQGPPGGIGNPGAVG--EKGEPGEAGEPGLPGEGGPPGP 1304
Query: 305 VSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSK--PKFDWVSAPDGPER 362
++ E G G GP P P P FPG P + DGP
Sbjct: 1305 KGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGP-VGFPGDPGPPGEPGPAGQDGPPG 1363
Query: 363 HFRFNGAGGGIGAPRRRAAALSGPWGSPPPP-PEQIHSAPGPRRPA-----------PAL 410
+G G G+P GP G P P P PGP P L
Sbjct: 1364 DKGDDGEPGQTGSP--------GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGL 1415
Query: 411 LAPPTFIFPAPTNGEPMRPGPPGLQELP-PLPPPTPPPTLQPPALQPTPLPVAPPLTPGL 469
PP P G P +PGP GL+ +P P+ P + P P P+ PP PGL
Sbjct: 1416 EGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS---PGPDGPPGPMGPPGLPGL 1472
Query: 470 GHKESALAPTAAPAL-----PPALAADQA----PAPSPAPAPT----VAEPSPPVSAPAP 516
P L PP ++ P P + P + PS P+ P P
Sbjct: 1473 KGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGP 1532
Query: 517 AAAPIKTRTRRNKGSRAARGATRKDGLHG 545
P + KGS G + G G
Sbjct: 1533 PGLPGPPGPKGAKGSSGPTGPKGEAGHPG 1561
Score = 68.6 bits (166), Expect = 2e-11
Identities = 120/477 (25%), Positives = 146/477 (30%), Gaps = 100/477 (20%)
Query: 130 HRGQGDPPSLRPLKPPPP---PRQLSVKDTVPRAPSQFPPPLETWKPPPPL--PSERQPA 184
+ G G P + K P P L P P+ P P T P + P ER P
Sbjct: 442 YEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPP 501
Query: 185 DRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCK 244
R P P + GP GG +G M +S++ L
Sbjct: 502 GR--------PGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQ-- 551
Query: 245 ITFKSRPSLAPPAASSSLAAKAS-LGGGGGGGLFAASGAISYAEVLKQGPL----PPGAA 299
++R +L PA L + +G G GGL G +V QGP PPG A
Sbjct: 552 ---QARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPG-----DVGPQGPRGVQGPPGPA 603
Query: 300 RPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDG 359
G R G DG AR +P T P FD ++ G
Sbjct: 604 GKPGRRGRA-----GSDG---------------ARGMPGQ---TGPKGDRGFDGLAGLPG 640
Query: 360 PERHFRFNGAGGGIGAP----RRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPT 415
+ H G G G P R GP G P PGPR LL P
Sbjct: 641 EKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLP--------GEPGPR----GLLGP-- 686
Query: 416 FIFPAPTNGEPMRPGPPGLQELPPLPPPT----PPPTLQPPALQPTPLPVAPPLTPGLGH 471
G P PGPPG+ + P P P PP Q P P G
Sbjct: 687 -------KGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIG 739
Query: 472 KESALAPTAAPALPPALAADQAPAPSPAPAPTVAE-------PSPPVSAPAPAAAPIKTR 524
P P LP AD P P + P P+ P P
Sbjct: 740 PPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADG 799
Query: 525 TRRNKGSRAARGATRKDGLHGD-------------GPRERATATVPDSSGGGGGGSG 568
R KG++ +G G GD GPR P GG G G
Sbjct: 800 IRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPG 856
Score = 68.6 bits (166), Expect = 2e-11
Identities = 132/533 (24%), Positives = 160/533 (30%), Gaps = 81/533 (15%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPP--PAPAGTL----L 105
PG + PPG P R P P P PP P P G
Sbjct: 648 PGPSGPPG---PPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQ 704
Query: 106 PGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFP 165
PGP P G P P + + + QG P + PP L K +P P
Sbjct: 705 PGPKGNVGPQGEPGPPGQ---QGNPGAQGLPGPQGAIGPPGEKGPLG-KPGLPGMPGADG 760
Query: 166 PPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAG-RARGGAPPHA 224
PP K PP Q P + P + G R T G + G P
Sbjct: 761 PPGHPGKEGPPGEKGGQGPPGPQGP-IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGF- 818
Query: 225 GEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAIS 284
+G+M D R + PP + G GG G G
Sbjct: 819 -KGDMGIKGD---------------RGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPG 862
Query: 285 YAEVLKQGPLP--PGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALP----- 337
L LP PG P G + G+ G G G P + P
Sbjct: 863 EKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERG 922
Query: 338 PPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQ- 396
P T PG K P GP NG G G P GP G P PP +
Sbjct: 923 PRGITGKPGPKGNSGG-DGPAGPPGERGPNGPQGPTGFP--------GPKGPPGPPGKDG 973
Query: 397 IHSAPGPR-------RPAPALLAPPTFIFPAPTNGE---------PMRPGPPGLQELPPL 440
+ PG R + P PP + P GE P PGPPG Q LP L
Sbjct: 974 LPGHPGQRGETGFQGKTGPP--GPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGL 1031
Query: 441 PPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAP 500
T P P PP G P A L ++ P P P
Sbjct: 1032 --AGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGA----LGLKGNEGPPGPPGP 1085
Query: 501 APTVAEPSPPVSA--------PAPAAAPIKTRTRRNKGSRAARGATRKDGLHG 545
A + E P +A P P P + G + +G +DGL G
Sbjct: 1086 AGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQG 1138
Score = 63.5 bits (153), Expect = 6e-10
Identities = 110/434 (25%), Positives = 139/434 (32%), Gaps = 103/434 (23%)
Query: 51 FPGSATPPGLM-VPREPQASPSTLPL-TLERPSPVMPP-PEEAAAVSAPPPAPAGTLLPG 107
FPG P GL +P P T + + P P P P A P P G PG
Sbjct: 1220 FPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPG 1279
Query: 108 -------PSKWQKPA-----GTPVPRIRRLLEASHRGQGDPPSLR-PLKPPPPPRQLSVK 154
P + +P G P P+ R +G+ P P P PP K
Sbjct: 1280 AVGEKGEPGEAGEPGLPGEGGPPGPKGER----GEKGESGPSGAAGPPGPKGPPGDDGPK 1335
Query: 155 DTVPRAPSQFP----PPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQG 210
+ P FP PP E P P + P D+ SP + GP
Sbjct: 1336 GSP--GPVGFPGDPGPPGE----PGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPP 1389
Query: 211 QTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGG 270
G G A P +GE A E+GL PP + + + + G
Sbjct: 1390 GKRGPP-GPAGPEGRQGEKG--AKGEAGLE-------------GPPGKTGPIGPQGAPGK 1433
Query: 271 GGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGE-------GCS 323
G GL G + + L P P G P+G + + G GE G
Sbjct: 1434 PGPDGLRGIPGPVG-EQGLPGSPGPDGPPGPMGPPGLPGLKGDSGP-KGEKGHPGLIGLI 1491
Query: 324 GPPSAPASQA-RALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAA 382
GPP + R LP P GP+ G G IG P
Sbjct: 1492 GPPGEQGEKGDRGLPGP---------------QGSSGPKGEQGITGPSGPIGPP------ 1530
Query: 383 LSGPWGSPPPP-PEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLP 441
GP G P PP P+ + GP P GE PGPPG P
Sbjct: 1531 --GPPGLPGPPGPKGAKGSSGPTGP----------------KGEAGHPGPPG-------P 1565
Query: 442 PPTPPPTLQPPALQ 455
P P +QP +Q
Sbjct: 1566 PGPPGEVIQPLPIQ 1579
Score = 48.1 bits (113), Expect = 2e-05
Identities = 69/240 (28%), Positives = 81/240 (33%), Gaps = 26/240 (10%)
Query: 349 PKFDWVSAPD--GPERHFRFNGAGGGIGAPRRRAAALSGPWGSPP--PPPEQIHSAPGPR 404
P +D S+P GP + GIG PR G G P P I PGP
Sbjct: 419 PYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGE----KGQKGEPAIIEPGMLIEGPPGPE 474
Query: 405 RPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPP-PTPPPTLQPPALQPTPLPVAP 463
PA L PP + P G+P GPPG LP P PP T+ + A
Sbjct: 475 GPA-GLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAG 533
Query: 464 PLTPGLGHKES--------ALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSP-----P 510
P + +ES A PA P L P P EP P
Sbjct: 534 SKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGP 593
Query: 511 VSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSG--GGGGGSG 568
P K R GS ARG + G GD + A +P G G G SG
Sbjct: 594 RGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFD-GLAGLPGEKGHRGDPGPSG 652
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 78.2 bits (191), Expect = 2e-14
Identities = 159/625 (25%), Positives = 183/625 (29%), Gaps = 123/625 (19%)
Query: 53 GSATPPGLMVPREPQASPSTLPLTLERPSPVMPP-----PEEAAAVSAP----------P 97
G PPGL VP P S P P P+ PP P +A A P P
Sbjct: 846 GDPGPPGLDVPGPPGERGS--PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903
Query: 98 PAPAGTL----------LPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPP 147
P P G L L G Q G P P +G P L P
Sbjct: 904 PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP-------TGEKGSKGEPGLPGPPGPMD 956
Query: 148 PRQLSVKDT-----VPRAPSQFPP------PLETWKP----PPPLPSERQPADRRITPAL 192
P L K +P P P P + +P P LP P P
Sbjct: 957 PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016
Query: 193 ATPASPP----TESQAG-PRNQGQTAGRARGGAPPHAG-------EGEMAQPADSESGLS 240
PP T G P QG G P G +G+ P S GL
Sbjct: 1017 PGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP 1076
Query: 241 LLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEV--LKQGPLPPGA 298
L K P L P + K S+G G GL GA + P PPG
Sbjct: 1077 GLPGP--KGEPGL--PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGP 1132
Query: 299 ARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQAR----ALP----------------- 337
G E G G G G P P + + +P
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP 1192
Query: 338 -PPPYTTFPGSK--------PKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWG 388
PP G K P + P G F G G G P AL GP G
Sbjct: 1193 GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKG 1252
Query: 389 SPPP--PPEQIHSAPGPR--RPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPT 444
+P P PP PGP + P PP GE PG PGL LP L
Sbjct: 1253 NPGPQGPP----GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1308
Query: 445 PPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAP-APSPAPAPT 503
PP LQ P PGL + P P P + P P
Sbjct: 1309 GPPGLQ-----------GNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPG 1357
Query: 504 VAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHG-DGPRERATATVPDSSGG 562
+ P P P P+ I KG G + GL G GP+ P G
Sbjct: 1358 LIGPPGPPGLPGPSGQSIII-----KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1412
Query: 563 GGGGSGASQTGAANTRAARHWLPFQ 587
G +G A R LP Q
Sbjct: 1413 DPGRNGLPGFDGAGGRKGDPGLPGQ 1437
Score = 77.4 bits (189), Expect = 4e-14
Identities = 153/592 (25%), Positives = 193/592 (32%), Gaps = 100/592 (16%)
Query: 51 FPGSATPPGLMVPREPQASP-------STLPLTLERP--SPVMPPPEEAAAVSAPPPAPA 101
FPGS PGL P P P S + +L P +P P P + P P
Sbjct: 133 FPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192
Query: 102 GTLLPGPSKWQKPAGTP-VPRIRRLLEASHRG-QGDPPSLRPLKPPPPPRQLSVKDTVPR 159
PGP P G P +P + + + +G +G+ PP PP Q+S
Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIS------- 245
Query: 160 APSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGG 219
+ P +E K LP +R P P + P PP + QG+ R + G
Sbjct: 246 -EQKRPIDVEFQKGDQGLPGDRGPPG---PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301
Query: 220 APPHAGE-------GEMAQPA----DSESGLSLLCKITFKSRPSLAPPAASSSLAAKASL 268
G+ G+ P D E G P L P + +
Sbjct: 302 KDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK--GDTGPPGPPGLVIPRPGTGITI-GEK 358
Query: 269 GGGGGGGLFAASGAISYAEVLKQGPL----PPGAA--RPLGEVSRGAQEAEGGDGDGEGC 322
G G GL G + + QGP PPGAA P G + + GD G
Sbjct: 359 GNIGLPGLPGEKGERGFPGI--QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI 416
Query: 323 S--GPPSAPASQ-ARALPPPPYTTFPGSKPKFDWVS-APDGP-----------ERHFR-- 365
S GPP A LP PP P P + P GP E+ +
Sbjct: 417 SIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGD 476
Query: 366 -----FNGAGGGIGAPRRRAA--ALSGPWGSPPPP-------------PEQIHSAPG-PR 404
FN G GI P + L GP GS P P+ + PG P
Sbjct: 477 KGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536
Query: 405 RPA-PALLAPPTFIFPAP----TNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPL 459
P P P I P GE PG PGL LP P P L P +P +
Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGI 596
Query: 460 PV----APPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPA 515
PP PGL + P P P P P P P
Sbjct: 597 TFKGERGPPGNPGLPGLPGNIGPMGPPGFGP-----PGPVGEKGIQGVAGNPGQP-GIPG 650
Query: 516 PAAAPIKTRTRRNK-GSRAARGATRKDGLHGDG--PRERATATVPDSSGGGG 564
P P +T T+ K G G GL GD P + +P S G G
Sbjct: 651 PKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPG 702
Score = 68.6 bits (166), Expect = 2e-11
Identities = 144/580 (24%), Positives = 179/580 (30%), Gaps = 96/580 (16%)
Query: 53 GSATPPGLMVPREP----QASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGP 108
G PPG+ +P P Q LP P +PP +E PP P G+ PG
Sbjct: 409 GDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG--PPGPPGS--PGD 464
Query: 109 SKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKP--PPPPRQLSV---KDTVPRAPSQ 163
Q G + G PP +P P P PP L K +A +
Sbjct: 465 KGLQGEQGVKGDKGDTCFNCIGTGISGPPG-QPGLPGLPGPPGSLGFPGQKGEKGQAGAT 523
Query: 164 FPPPLETWKPPPPLP----SERQPADRRITPA-------LATPASPPTESQAGPRNQGQT 212
P L P P S+ +P D P L +P +P G Q
Sbjct: 524 GPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583
Query: 213 AGRARGGAPPHA--GEGEMAQPADSESGL-SLLCKITFKSRPSLAPPAASSSLAAKASLG 269
G P +GE P + GL L I P PP + G
Sbjct: 584 PGLPGPKGEPGGITFKGERGPPGNP--GLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641
Query: 270 GGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAP 329
G G+ G P PG G+V G G G P
Sbjct: 642 NPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP 701
Query: 330 ASQARALPPPPYTT-FPG--------SKPKFDWVSAPDGP--------ERHFRFNGAGGG 372
LP PP FPG P + P GP E F G G
Sbjct: 702 GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGP 761
Query: 373 IGAPRRRAAALSGPWGS-----PPPPPEQ--IHSAPGPRRPA-----PALLAPPTF--IF 418
G P + A GP G PP PP + + PGP+ P + PP I
Sbjct: 762 PGLPGFKGAL--GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIG 819
Query: 419 PAPTNGEPMRPGP---PGLQELP-----PLPP----PTPPPTLQPPALQPTPLPVAPPLT 466
G P PGP PGL +P P PP P PP P + P P+ PP +
Sbjct: 820 VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879
Query: 467 PGLGHKESA------------LAPTAAP---ALP-----PALAADQAPAPSPA-PAPTVA 505
PGL K A + P P +P P L D P P PT
Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939
Query: 506 EPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHG 545
+ S P+ +KG + G G+ G
Sbjct: 940 KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSG 979
Score = 60.5 bits (145), Expect = 5e-09
Identities = 109/446 (24%), Positives = 140/446 (31%), Gaps = 83/446 (18%)
Query: 145 PPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQA 204
PP PR D +P PP + + PP LP TP L P P +
Sbjct: 70 PPGPRGQKGDDGIPG-----PPGPKGIRGPPGLPGFPG------TPGL--PGMPGHDGAP 116
Query: 205 GPRN----QGQTAGRARGGAPPHAG-EGEMAQPA----DSESGLSLLCKITF-KSRPSLA 254
GP+ G R G+P G +G P E G ++ + K P
Sbjct: 117 GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176
Query: 255 PPAASSSLAAKASLGGG----GGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQ 310
P L + G G GL G PPG P G + Q
Sbjct: 177 GPPGIQGLPGPTGIPGPIGPPGPPGLMGPPG-------------PPGLPGPKGNMGLNFQ 223
Query: 311 EAEGGDGDGEGCSGPPSAPASQARALPPPPYTT------FPGSK--PKFDWVSAPDGPER 362
+G G+ +G GPP P + P PG + P + P GP
Sbjct: 224 GPKGEKGE-QGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG 282
Query: 363 HFRFNGAGGGIGAPRRRAA----------ALSGPWGSPPPPPEQIHSAPGPRRPAPALLA 412
+ G G G P +R + G G P P E ++
Sbjct: 283 GEK--GEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340
Query: 413 PPTFIFPAPTNGEPMR-------PGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPL 465
PP + P P G + PG PG + P PP L P P PP
Sbjct: 341 PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG 400
Query: 466 TPG-LGHKESALAPTAAPALPPAL----AADQAPAPSPAPAPTVAEPSPPVSAPAPAAAP 520
PG G K P + PP L A P P P PA PS + P P P
Sbjct: 401 FPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP-PGPAGPHIPPSDEICEPGPPGPP 459
Query: 521 IKTRTRRNKGSRAARGATRKDGLHGD 546
GS +G + G+ GD
Sbjct: 460 ---------GSPGDKGLQGEQGVKGD 476
Score = 54.3 bits (129), Expect = 3e-07
Identities = 70/259 (27%), Positives = 89/259 (34%), Gaps = 41/259 (15%)
Query: 308 GAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSK--PKFDWVSAPDGPERHFR 365
G G GD +G GPP + PP FPG+ P GP+
Sbjct: 69 GPPGPRGQKGD-DGIPGPPGPKGIRG----PPGLPGFPGTPGLPGMPGHDGAPGPQGIPG 123
Query: 366 FNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGE 425
NG G G P + G G P PP PG + +++ P P G
Sbjct: 124 CNGTKGERGFPG--SPGFPGLQGPPGPP-----GIPGMKGEPGSIIMSS---LPGP-KGN 172
Query: 426 PMRPGPPGLQELP-------PLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHK----ES 474
P PGPPG+Q LP P+ PP PP + PP P LP P GL + E
Sbjct: 173 PGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPG--PPGLP-GPKGNMGLNFQGPKGEK 229
Query: 475 ALAPTAAPALPPALAADQ--------APAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTR 526
P PP ++Q P P PP P + +
Sbjct: 230 GEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDR-GPPGPPGIRGPPGPPGGEKGEK 288
Query: 527 RNKGSRAARGATRKDGLHG 545
+G RG KDG +G
Sbjct: 289 GEQGEPGKRGKPGKDGENG 307
Score = 51.6 bits (122), Expect = 2e-06
Identities = 108/436 (24%), Positives = 137/436 (31%), Gaps = 63/436 (14%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW 111
PG PGL + + P + L P +P P+ + P P G
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGL----PGLPGPKGEPGLPGYPGNPGIKGSVGDPGL 1105
Query: 112 QKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPL--- 168
GTP +GQ P PP P+ +S P P + P P+
Sbjct: 1106 PGLPGTP----------GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE-PGPVGGG 1154
Query: 169 -ETWKPPPPLPSERQPADRRITPA--LATPASPPTESQAGPRNQGQTAGRARGGAPPHAG 225
+P PP + D PA P P + P G + + GG P G
Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214
Query: 226 EGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISY 285
+ P E G F P S A + G G G G +
Sbjct: 1215 NPGLPGPK-GEPGFH-----GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGF 1268
Query: 286 AEVL-KQGPLP-PGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQAR--------- 334
+ +GP PG GE Q G +G GPP + R
Sbjct: 1269 QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1328
Query: 335 -ALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAAL-----SGPWG 388
LP P FPG K V GPE G G G P ++ +GP G
Sbjct: 1329 PGLPGVP--GFPGMKGP-SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPG 1385
Query: 389 SPPPP-------PEQIHSAPGPRRPA--PALLAPPTFIFPAPTNGEPMRPGPPGLQEL-- 437
P P P+ PGP P P P F G+P PG PG + L
Sbjct: 1386 IPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDG 1445
Query: 438 PPLP-----PPTPPPT 448
PP P PP PP T
Sbjct: 1446 PPGPDGLQGPPGPPGT 1461
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 77.8 bits (190), Expect = 3e-14
Identities = 114/456 (25%), Positives = 152/456 (33%), Gaps = 112/456 (24%)
Query: 190 PALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITF-K 248
P PA PP + A + T + G A +D G L +T +
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQA-------GRNALLSDISKGKKLKKTVTNDR 54
Query: 249 SRPSLAPPAASSSLAAKASLGGGGG---------GGLFAASGAISYAEVLKQGP------ 293
S P L P + + GGGGG GG F G + + G
Sbjct: 55 SAPILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRST 114
Query: 294 --------------LPPG----AARPLGEVSRGAQEAEGGDGDGEGCSG------PPSAP 329
LPPG +A+P S + G G PP P
Sbjct: 115 ANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRP 174
Query: 330 --ASQARALPPP-PYTTFP--------GSKPKFDWVSAPDGPER--------HFRFN-GA 369
S+ ++PPP P T P GS P P GP + F N G
Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPP------VPGGPRQPSPGPTPPPFPGNRGT 228
Query: 370 GGGIGAPRRRAAALSGPWGS---------------PPPPPEQIHSAPGPRRPAPALLAPP 414
G G+ R+ + S P+ + PPPPP + + P R A PP
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA----VPP 284
Query: 415 TFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPL-----TPGL 469
P P N +P P P PPP PPP+ +P P P+ P TP L
Sbjct: 285 ----PPPQNNKPPVPSTPRPSASSQAPPPPPPPS------RPGPPPLPPSSSGNDETPRL 334
Query: 470 GHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNK 529
+ +L+ + P P + P PS P P V +P P S P P P+ +R
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP-PGRSGPLPPPPPV---SRNGS 390
Query: 530 GSRAARGATRKDGLHG-DGPRERATATVPDSSGGGG 564
SRA + G D PR +P G
Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAG 426
Score = 75.9 bits (185), Expect = 1e-13
Identities = 100/398 (25%), Positives = 134/398 (33%), Gaps = 85/398 (21%)
Query: 126 LEASHRGQGDPPSLRPLKPPPPPRQLSVKD-TVPRAPSQFPPPLETWKPPPPLPSE-RQP 183
L ++ D RP PP R S K + P P +FP P + PP P R P
Sbjct: 111 LRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP 170
Query: 184 ADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLC 243
R + PP S P Q++ RG P G QP+
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPRPI---QSSPHNRGSPPVPGGP---RQPS---------- 214
Query: 244 KITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLG 303
P PP + G GGG S S + + PLPP +R L
Sbjct: 215 -------PGPTPPPFPGNR------GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALD 261
Query: 304 EVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERH 363
+ PP PPPP G++P + P P +
Sbjct: 262 D------------------KPPP----------PPPPV----GNRPSIHREAVPPPPPQ- 288
Query: 364 FRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLA-PPTFIFP--- 419
N PR A++ + P PPPPP S PGP P+ T P
Sbjct: 289 ---NNKPPVPSTPRPSASSQAPP---PPPPP----SRPGPPPLPPSSSGNDETPRLPQRN 338
Query: 420 -APTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAP 478
+ ++ P P P LPP P PPP ++ P + PLP PP++ +
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVS------RNGSTS 392
Query: 479 TAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAP 516
A PA P + +P P P + P AP P
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP 430
Score = 70.5 bits (171), Expect = 5e-12
Identities = 124/484 (25%), Positives = 161/484 (33%), Gaps = 128/484 (26%)
Query: 94 SAPPPAPAGTLLPGPSKWQKPAGT---PVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQ 150
S PP P G + P+G PVP HR G P R PPP P
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVP------SPGHRS-GPPEPQRNRMPPPRP-- 174
Query: 151 LSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQG 210
V P PPP+ P P P + P +R P P P + G
Sbjct: 175 -----DVGSKPDSIPPPV----PSTPRPIQSSPHNRGSPPVPGGPRQP---------SPG 216
Query: 211 QTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGG 270
T G G G + Q S S F +RP L PP S +L K
Sbjct: 217 PTPPPFPGNRGTALGGGSIRQSPLSSSS-------PFSNRPPL-PPTPSRALDDK----- 263
Query: 271 GGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPA 330
P PP RP + R A + P P+
Sbjct: 264 -------------------PPPPPPPVGNRP--SIHREAVPPPPPQNNKPPVPSTP-RPS 301
Query: 331 SQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSP 390
+ ++A PPPP + PG P S D R P+R + S S
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPR------------LPQRNLSLSS----ST 345
Query: 391 PPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQ 450
PP P +PG P P PP+ P P P R G PLPPP
Sbjct: 346 PPLP-----SPGRSGPLP---PPPSERPPPPVRDPPGRSG--------PLPPP------- 382
Query: 451 PPALQPTPLPVAPPLTPGLGHKESALAPTAA--PALPPALAADQAPAPSPAPAPTVA--- 505
PP + A P TP L + +P + P LPP + AP P P P+ ++
Sbjct: 383 PPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP-PPPPPSTSIRNGF 441
Query: 506 EPSP------------PVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERAT 553
+ SP P+S P + +T ++ S+ AR +R G RER
Sbjct: 442 QDSPCEDEWESRFYFHPISDLPPPEPYV--QTTKSYPSKLARNESRS----GSNRRERGA 495
Query: 554 ATVP 557
+P
Sbjct: 496 PPLP 499
Score = 63.9 bits (154), Expect = 4e-10
Identities = 103/364 (28%), Positives = 124/364 (34%), Gaps = 115/364 (31%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPP-PEEAAAVSAPPPAPA--GTLLPGP 108
P S PP PR Q+SP R SP +P P + + PPP P GT L G
Sbjct: 180 PDSIPPPVPSTPRPIQSSPHN------RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG 233
Query: 109 SKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPL 168
S Q P + P S RP PP P R L K P P P +
Sbjct: 234 SIRQSPLSS----------------SSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI 277
Query: 169 ETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAP--PHAGE 226
PPP P +P P +TP P SQA P +R G P P +
Sbjct: 278 HREAVPPPPPQNNKP------PVPSTP-RPSASSQAPP----PPPPPSRPGPPPLPPSSS 326
Query: 227 GEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYA 286
G P + LSL S P L P S
Sbjct: 327 GNDETPRLPQRNLSL-----SSSTPPLPSPGRS--------------------------- 354
Query: 287 EVLKQGPL-PPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFP 345
GPL PP + RP V D G SGP LPPPP +
Sbjct: 355 -----GPLPPPPSERPPPPVR-----------DPPGRSGP----------LPPPPPVSRN 388
Query: 346 GSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRR 405
GS + + P P+ R G+ +PR SGP PP PP++ SA P
Sbjct: 389 GSTSR----ALPATPQLPSR-----SGVDSPR------SGP--RPPLPPDR-PSAGAPPP 430
Query: 406 PAPA 409
P P+
Sbjct: 431 PPPS 434
Score = 53.9 bits (128), Expect = 5e-07
Identities = 66/228 (28%), Positives = 87/228 (38%), Gaps = 45/228 (19%)
Query: 11 GGGSRKVQP-SDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREP--- 66
GGGS + P S +P S R L P S+A+ PP V P
Sbjct: 231 GGGSIRQSPLSSSSPFSNRPPL--PPTPSRAL----------DDKPPPPPPPVGNRPSIH 278
Query: 67 -QASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAG----TP-VP 120
+A P P + P P P P ++ PPP P+ PGP + TP +P
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR---PGPPPLPPSSSGNDETPRLP 335
Query: 121 RIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSE 180
+ L +S P PL PPP R P P + PP PPPP
Sbjct: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSER--------PPPPVRDPPGRSGPLPPPP---- 383
Query: 181 RQPADRRITPALATPASPPTESQAG---PRNQGQ---TAGRARGGAPP 222
P R + + A PA+P S++G PR+ + R GAPP
Sbjct: 384 --PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPP 429
Score = 41.6 bits (96), Expect = 0.002
Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 34/179 (18%)
Query: 54 SATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQK 113
S+TPP +P ++ P P + P PV PP + + PPP G +
Sbjct: 343 SSTPP---LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRN----GSTSRAL 395
Query: 114 PAGTPVPRIRRLLEASHRGQGDP-PSLRPLK--PPPPPRQLSVKDTVPRAPSQ------- 163
PA +P R +++ G P P RP PPPPP S+++ +P +
Sbjct: 396 PATPQLPS-RSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRF 454
Query: 164 FPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPP 222
+ P+ PP P + T S P++ G + R GAPP
Sbjct: 455 YFHPISDLPPPEPY--------------VQTTKSYPSKLARNESRSG--SNRRERGAPP 497
Score = 30.4 bits (67), Expect = 5.3
Identities = 22/70 (31%), Positives = 27/70 (38%), Gaps = 8/70 (11%)
Query: 507 PSPPVSAPAPAAAPIKT-RTRRNKGSRAARGATRKDGLHGDGPRERAT-------ATVPD 558
P PP P P A T + NK +A R A D G ++ T P
Sbjct: 4 PPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPK 63
Query: 559 SSGGGGGGSG 568
+G GGGG G
Sbjct: 64 GAGAGGGGGG 73
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 77.8 bits (190), Expect = 3e-14
Identities = 114/456 (25%), Positives = 152/456 (33%), Gaps = 112/456 (24%)
Query: 190 PALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITF-K 248
P PA PP + A + T + G A +D G L +T +
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQA-------GRNALLSDISKGKKLKKTVTNDR 54
Query: 249 SRPSLAPPAASSSLAAKASLGGGGG---------GGLFAASGAISYAEVLKQGP------ 293
S P L P + + GGGGG GG F G + + G
Sbjct: 55 SAPILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRST 114
Query: 294 --------------LPPG----AARPLGEVSRGAQEAEGGDGDGEGCSG------PPSAP 329
LPPG +A+P S + G G PP P
Sbjct: 115 ANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRP 174
Query: 330 --ASQARALPPP-PYTTFP--------GSKPKFDWVSAPDGPER--------HFRFN-GA 369
S+ ++PPP P T P GS P P GP + F N G
Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPP------VPGGPRQPSPGPTPPPFPGNRGT 228
Query: 370 GGGIGAPRRRAAALSGPWGS---------------PPPPPEQIHSAPGPRRPAPALLAPP 414
G G+ R+ + S P+ + PPPPP + + P R A PP
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA----VPP 284
Query: 415 TFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPL-----TPGL 469
P P N +P P P PPP PPP+ +P P P+ P TP L
Sbjct: 285 ----PPPQNNKPPVPSTPRPSASSQAPPPPPPPS------RPGPPPLPPSSSGNDETPRL 334
Query: 470 GHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNK 529
+ +L+ + P P + P PS P P V +P P S P P P+ +R
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP-PGRSGPLPPPPPV---SRNGS 390
Query: 530 GSRAARGATRKDGLHG-DGPRERATATVPDSSGGGG 564
SRA + G D PR +P G
Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAG 426
Score = 75.9 bits (185), Expect = 1e-13
Identities = 100/398 (25%), Positives = 134/398 (33%), Gaps = 85/398 (21%)
Query: 126 LEASHRGQGDPPSLRPLKPPPPPRQLSVKD-TVPRAPSQFPPPLETWKPPPPLPSE-RQP 183
L ++ D RP PP R S K + P P +FP P + PP P R P
Sbjct: 111 LRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP 170
Query: 184 ADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLC 243
R + PP S P Q++ RG P G QP+
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPRPI---QSSPHNRGSPPVPGGP---RQPS---------- 214
Query: 244 KITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLG 303
P PP + G GGG S S + + PLPP +R L
Sbjct: 215 -------PGPTPPPFPGNR------GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALD 261
Query: 304 EVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERH 363
+ PP PPPP G++P + P P +
Sbjct: 262 D------------------KPPP----------PPPPV----GNRPSIHREAVPPPPPQ- 288
Query: 364 FRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLA-PPTFIFP--- 419
N PR A++ + P PPPPP S PGP P+ T P
Sbjct: 289 ---NNKPPVPSTPRPSASSQAPP---PPPPP----SRPGPPPLPPSSSGNDETPRLPQRN 338
Query: 420 -APTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAP 478
+ ++ P P P LPP P PPP ++ P + PLP PP++ +
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVS------RNGSTS 392
Query: 479 TAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAP 516
A PA P + +P P P + P AP P
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP 430
Score = 70.5 bits (171), Expect = 5e-12
Identities = 124/484 (25%), Positives = 161/484 (33%), Gaps = 128/484 (26%)
Query: 94 SAPPPAPAGTLLPGPSKWQKPAGT---PVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQ 150
S PP P G + P+G PVP HR G P R PPP P
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVP------SPGHRS-GPPEPQRNRMPPPRP-- 174
Query: 151 LSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQG 210
V P PPP+ P P P + P +R P P P + G
Sbjct: 175 -----DVGSKPDSIPPPV----PSTPRPIQSSPHNRGSPPVPGGPRQP---------SPG 216
Query: 211 QTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGG 270
T G G G + Q S S F +RP L PP S +L K
Sbjct: 217 PTPPPFPGNRGTALGGGSIRQSPLSSSS-------PFSNRPPL-PPTPSRALDDK----- 263
Query: 271 GGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPA 330
P PP RP + R A + P P+
Sbjct: 264 -------------------PPPPPPPVGNRP--SIHREAVPPPPPQNNKPPVPSTP-RPS 301
Query: 331 SQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSP 390
+ ++A PPPP + PG P S D R P+R + S S
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPR------------LPQRNLSLSS----ST 345
Query: 391 PPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQ 450
PP P +PG P P PP+ P P P R G PLPPP
Sbjct: 346 PPLP-----SPGRSGPLP---PPPSERPPPPVRDPPGRSG--------PLPPP------- 382
Query: 451 PPALQPTPLPVAPPLTPGLGHKESALAPTAA--PALPPALAADQAPAPSPAPAPTVA--- 505
PP + A P TP L + +P + P LPP + AP P P P+ ++
Sbjct: 383 PPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP-PPPPPSTSIRNGF 441
Query: 506 EPSP------------PVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERAT 553
+ SP P+S P + +T ++ S+ AR +R G RER
Sbjct: 442 QDSPCEDEWESRFYFHPISDLPPPEPYV--QTTKSYPSKLARNESRS----GSNRRERGA 495
Query: 554 ATVP 557
+P
Sbjct: 496 PPLP 499
Score = 63.9 bits (154), Expect = 4e-10
Identities = 103/364 (28%), Positives = 124/364 (34%), Gaps = 115/364 (31%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPP-PEEAAAVSAPPPAPA--GTLLPGP 108
P S PP PR Q+SP R SP +P P + + PPP P GT L G
Sbjct: 180 PDSIPPPVPSTPRPIQSSPHN------RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG 233
Query: 109 SKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPL 168
S Q P + P S RP PP P R L K P P P +
Sbjct: 234 SIRQSPLSS----------------SSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI 277
Query: 169 ETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAP--PHAGE 226
PPP P +P P +TP P SQA P +R G P P +
Sbjct: 278 HREAVPPPPPQNNKP------PVPSTP-RPSASSQAPP----PPPPPSRPGPPPLPPSSS 326
Query: 227 GEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYA 286
G P + LSL S P L P S
Sbjct: 327 GNDETPRLPQRNLSL-----SSSTPPLPSPGRS--------------------------- 354
Query: 287 EVLKQGPL-PPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFP 345
GPL PP + RP V D G SGP LPPPP +
Sbjct: 355 -----GPLPPPPSERPPPPVR-----------DPPGRSGP----------LPPPPPVSRN 388
Query: 346 GSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRR 405
GS + + P P+ R G+ +PR SGP PP PP++ SA P
Sbjct: 389 GSTSR----ALPATPQLPSR-----SGVDSPR------SGP--RPPLPPDR-PSAGAPPP 430
Query: 406 PAPA 409
P P+
Sbjct: 431 PPPS 434
Score = 53.9 bits (128), Expect = 5e-07
Identities = 66/228 (28%), Positives = 87/228 (38%), Gaps = 45/228 (19%)
Query: 11 GGGSRKVQP-SDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREP--- 66
GGGS + P S +P S R L P S+A+ PP V P
Sbjct: 231 GGGSIRQSPLSSSSPFSNRPPL--PPTPSRAL----------DDKPPPPPPPVGNRPSIH 278
Query: 67 -QASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAG----TP-VP 120
+A P P + P P P P ++ PPP P+ PGP + TP +P
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR---PGPPPLPPSSSGNDETPRLP 335
Query: 121 RIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSE 180
+ L +S P PL PPP R P P + PP PPPP
Sbjct: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSER--------PPPPVRDPPGRSGPLPPPP---- 383
Query: 181 RQPADRRITPALATPASPPTESQAG---PRNQGQ---TAGRARGGAPP 222
P R + + A PA+P S++G PR+ + R GAPP
Sbjct: 384 --PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPP 429
Score = 41.6 bits (96), Expect = 0.002
Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 34/179 (18%)
Query: 54 SATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQK 113
S+TPP +P ++ P P + P PV PP + + PPP G +
Sbjct: 343 SSTPP---LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRN----GSTSRAL 395
Query: 114 PAGTPVPRIRRLLEASHRGQGDP-PSLRPLK--PPPPPRQLSVKDTVPRAPSQ------- 163
PA +P R +++ G P P RP PPPPP S+++ +P +
Sbjct: 396 PATPQLPS-RSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRF 454
Query: 164 FPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPP 222
+ P+ PP P + T S P++ G + R GAPP
Sbjct: 455 YFHPISDLPPPEPY--------------VQTTKSYPSKLARNESRSG--SNRRERGAPP 497
Score = 30.4 bits (67), Expect = 5.3
Identities = 22/70 (31%), Positives = 27/70 (38%), Gaps = 8/70 (11%)
Query: 507 PSPPVSAPAPAAAPIKT-RTRRNKGSRAARGATRKDGLHGDGPRERAT-------ATVPD 558
P PP P P A T + NK +A R A D G ++ T P
Sbjct: 4 PPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPK 63
Query: 559 SSGGGGGGSG 568
+G GGGG G
Sbjct: 64 GAGAGGGGGG 73
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 77.8 bits (190), Expect = 3e-14
Identities = 108/456 (23%), Positives = 149/456 (32%), Gaps = 156/456 (34%)
Query: 65 EPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRR 124
E + +P + + + PPP A S PPP P + P P
Sbjct: 383 ERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPP---------------- 426
Query: 125 LLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPA 184
PL PPPPP P +P P P PPPP E++
Sbjct: 427 ----------------PLCPPPPP---------PVSPPPLPSP-----PPPPAQEEQEE- 455
Query: 185 DRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCK 244
+P PA+ + P Q A R A P P+ + G
Sbjct: 456 ----SPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGG------ 505
Query: 245 ITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGE 304
PP S ++A K++ ++ + ++Q +P +AR
Sbjct: 506 ----------PPEDSPTVAPKST----------------TFLKNIRQFIMPVVSARSSRV 539
Query: 305 VSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHF 364
+ + + PP P + + PP TT P P P
Sbjct: 540 IKTPRRFMD---------EDPPKPPKVEVSPVLRPPITTSP---------PVPQEP---- 577
Query: 365 RFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNG 424
A + P +P PP + P RR ++L PTF + + T
Sbjct: 578 ----------------APVPSPPRAPTPPSTPV-PLPEKRR---SILREPTFRWTSLT-- 615
Query: 425 EPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPV----------APPLTPGLGHKES 474
+ELPP PPP PPP PPA P P P AP TP H
Sbjct: 616 ----------RELPP-PPPAPPP---PPAPSPPPAPATSSRRPLLLRAPQFTPSEAH--- 658
Query: 475 ALAPTAAPALPPALAADQAPAPSPAPA-PTVAEPSP 509
L + PP L A +AP P P PA + AEP P
Sbjct: 659 -LKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEP 693
Score = 77.0 bits (188), Expect = 5e-14
Identities = 145/570 (25%), Positives = 188/570 (32%), Gaps = 120/570 (21%)
Query: 54 SATPPGLMVPREPQASPSTLPLTLERPSPV--MPPPEEAAAVSAPPPAP-----AGTLLP 106
S+ PPG P P + +P ER SP+ + PP + SAPPPAP A +P
Sbjct: 1811 SSEPPGGEDP--PLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVP 1868
Query: 107 GPSKWQKPAGT----PVPRIRRLLEASHR--GQGDPPSLRPLKPPPPPRQLSVKDTVPRA 160
S ++P G P+P +H GDP P PP R PR
Sbjct: 1869 NYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDF-----PAPPRRSRRPSPLAPR- 1922
Query: 161 PSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGA 220
PP W PP S P R P A PT + P +
Sbjct: 1923 -----PPPSRWASPPLKTS---PQLRVPPPTSVVTALTPTSGELAPPGPAPSP------- 1967
Query: 221 PPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKA---SLGGGGGGGLF 277
PP G + + SGLS + F + P +AA A S GG G
Sbjct: 1968 PPPEDLGPDFEDMEVVSGLSA-ADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEE 2026
Query: 278 AASGAISYAE----VLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGE------GCSGPPS 327
+S Y V+ L P A + + +G D + E G PPS
Sbjct: 2027 ESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPS 2086
Query: 328 AP---------ASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRR 378
P A+ RA PP + D+V G G G G PR
Sbjct: 2087 GPGVVRAGVLGAAGDRARPPEDLPS-----EIVDFVLKNLG--------GPGDGGAGPRE 2133
Query: 379 RAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELP 438
+ PP PP S +P+ L A P PT PG PG++ L
Sbjct: 2134 ESL--------PPAPPLANGS-----QPSQGLTASPA----DPTRTFAWLPGAPGVRVLS 2176
Query: 439 PLPPPTPPPTLQPPALQPTPL------------PVAPPLTPGLGHKESALAPTAAPALPP 486
P P PP + L PV PP+ K+ L PT +P P
Sbjct: 2177 LGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPV------KQPPLPPTISPTAPT 2230
Query: 487 ALAADQAPAPSPAPAPTVAEPSPPVSAP--------APAAAP-----IKTRTRRNKGSRA 533
+ P P V P+PP P PA+ P +K + + S
Sbjct: 2231 SWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPP 2290
Query: 534 ARGATRKDGLHGDGPRERATATVPDSSGGG 563
A + L DG T VP GG
Sbjct: 2291 APPPYKAPRLDEDGEASEDTPQVPGLGSGG 2320
Score = 74.7 bits (182), Expect = 2e-13
Identities = 98/396 (24%), Positives = 134/396 (33%), Gaps = 101/396 (25%)
Query: 136 PPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPA---DRRITPAL 192
PP L P P PPP L T P P PPP PPPLPS P ++ +P
Sbjct: 403 PPPLTPPAPSPPP-PLPPPSTSPPPPLCPPPPPPV--SPPPLPSPPPPPAQEEQEESPPP 459
Query: 193 ATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPS 252
PA+ + P Q A R A P P+ + G
Sbjct: 460 VVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGG-------------- 505
Query: 253 LAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEA 312
PP S ++A K++ ++ + ++Q +P +AR + +
Sbjct: 506 --PPEDSPTVAPKST----------------TFLKNIRQFIMPVVSARSSRVIKTPRRFM 547
Query: 313 EGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGG 372
+ PP P + + PP TT P P P
Sbjct: 548 D---------EDPPKPPKVEVSPVLRPPITTSP---------PVPQEP------------ 577
Query: 373 IGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPP 432
A + P +P PP + P RR ++L PTF + + T
Sbjct: 578 --------APVPSPPRAPTPPSTPV-PLPEKRR---SILREPTFRWTSLT---------- 615
Query: 433 GLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQ 492
+ELPP PPP PPP PPA P P P P L AP P+ +
Sbjct: 616 --RELPP-PPPAPPP---PPAPSPPPAPATSSRRPLL-----LRAPQFTPSEAHLKIYES 664
Query: 493 APAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRN 528
P P AP EP PP + +PA + R N
Sbjct: 665 VLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTN 700
Score = 70.9 bits (172), Expect = 4e-12
Identities = 103/400 (25%), Positives = 130/400 (32%), Gaps = 54/400 (13%)
Query: 131 RGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPS--ERQPADRRI 188
RG+G PL PPPR V T P+ P++ T + L R A +
Sbjct: 150 RGRGRKHKTTPL---PPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAP 206
Query: 189 TPALATPASP------PTESQAGPRNQGQTAGRARGGAP--PHAGEGEMAQPADSESGLS 240
P++P P AGP + Q A A P P ++G S
Sbjct: 207 RSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTG-S 265
Query: 241 LLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAAR 300
CK P SS + G G GGGL +S A+ +K G L G
Sbjct: 266 WKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLES 325
Query: 301 PLGEVSRGAQEAEGGDGD----GEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSA 356
G+ G E D G G G P + + K K
Sbjct: 326 GQGQ---GQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDK------ 376
Query: 357 PDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTF 416
+G E+ R A AA PPPP +P P P P+ PP
Sbjct: 377 -EGEEKEER-------AVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPP-- 426
Query: 417 IFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVA--------PPLTPG 468
P+ P PP PPLP P PPP + P P+ A PPLTP
Sbjct: 427 ---------PLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPS 477
Query: 469 LGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPS 508
+ A PP A P +PTVA S
Sbjct: 478 QRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKS 517
Score = 61.6 bits (148), Expect = 2e-09
Identities = 114/497 (22%), Positives = 153/497 (30%), Gaps = 100/497 (20%)
Query: 84 MPPPEEAAAVSAPPPAPA------GT--LLPGPSKWQKPAGTPVPRIRRLLEAS--HRGQ 133
+PPP A PP PA GT ++ ++ + A P R E S R +
Sbjct: 161 LPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSR 220
Query: 134 GDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPL-PSERQPADRRITPAL 192
G PP +P P R+ V A P P +PPPP+ P + Q +
Sbjct: 221 GRPPG----RPAGPCRRKQQAVVVAEAAVTIPKP----EPPPPVVPVKHQTGSWKCKEGP 272
Query: 193 ATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPS 252
P R GR RGG P + LSL +S
Sbjct: 273 GPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSL----GLESGQG 328
Query: 253 LAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEA 312
S + +G G GG P + L + +E
Sbjct: 329 QGQHEESWQDVPQRRVGSGQGGS-----------------PCWKKQEQKLDDEEEEKKEE 371
Query: 313 EGGDGDGEGCSGP-------PSAPASQARALPPPPYTT-FPGSKPKFDWVSAPDGPERHF 364
E D +GE P+A +A+ LPPPP T P P S P
Sbjct: 372 EEKDKEGEEKEERAVAEEMMPAAEKEEAK-LPPPPLTPPAPSPPPPLPPPSTSPPPPL-- 428
Query: 365 RFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAP----PTFIFPA 420
P P SPPPPP Q P PA + P
Sbjct: 429 ----------CPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQ 478
Query: 421 PTNGEPMRPGPPGLQELPPLP------PPTPPPTLQPPA------LQPTPLPVA------ 462
E R GP G P P PP PT+ P + ++ +PV
Sbjct: 479 RAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSR 538
Query: 463 ------------PPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPP 510
PP P + ++P P + + Q PAP P+P PS P
Sbjct: 539 VIKTPRRFMDEDPPKPPKV-----EVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTP 593
Query: 511 VSAPAPAAAPIKTRTRR 527
V P + ++ T R
Sbjct: 594 VPLPEKRRSILREPTFR 610
Score = 57.0 bits (136), Expect = 5e-08
Identities = 57/192 (29%), Positives = 73/192 (38%), Gaps = 37/192 (19%)
Query: 327 SAPASQARALPPPPYTTFPGSK-PKFDW-VSAPDGPERHFRFNGAGGGIGAPRRRAAALS 384
+A +Q P P + PG + P D V P PERH + P R +
Sbjct: 1797 AAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQN----LDPPLRPDSG-- 1850
Query: 385 GPWGSPPPPPEQIHSAP------GPRR---------PAPALLAPPTFIFPAPTNGEPMRP 429
+PPP P A P R P P+ +P + PT G+P P
Sbjct: 1851 ---SAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFP 1907
Query: 430 GPPGLQELP-PLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPAL 488
PP P PL P PP P L+ +P PP T + +AL PT+ PP
Sbjct: 1908 APPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVV----TALTPTSGELAPP-- 1961
Query: 489 AADQAPAPSPAP 500
PAPSP P
Sbjct: 1962 ----GPAPSPPP 1969
Score = 50.1 bits (118), Expect = 7e-06
Identities = 102/476 (21%), Positives = 135/476 (28%), Gaps = 125/476 (26%)
Query: 57 PPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAG 116
PP + P P P P + P P+ PPP +PPP P+ P P Q+
Sbjct: 402 PPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPV---SPPPLPS----PPPPPAQEEQE 454
Query: 117 TPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPP 176
P + + RG +PP P Q + ++ P E PP P
Sbjct: 455 ESPPPVVPATCSRKRG----------RPPLTPSQRAEREAARAGP-------EGTSPPTP 497
Query: 177 LPSERQPADRRITPALATPASP----------PTESQAGPRNQGQTAGRARGGAPPHAGE 226
PS +P +A ++ P S R +T R PP +
Sbjct: 498 TPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSR-VIKTPRRFMDEDPPKPPK 556
Query: 227 GEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYA 286
E++ P L PP +S + +
Sbjct: 557 VEVS--------------------PVLRPPITTSPPVPQEP----------------APV 580
Query: 287 EVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPG 346
+ P PP PL E R P S R LPPPP P
Sbjct: 581 PSPPRAPTPPSTPVPLPEKRRSILRE------------PTFRWTSLTRELPPPPPAPPPP 628
Query: 347 SKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRP 406
P S P P RR L P +P +I+
Sbjct: 629 PAP-----SPPPAP-------------ATSSRRPLLLRAPQFTPSEAHLKIYE------- 663
Query: 407 APALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPP--------PTLQPPALQPTP 458
++L PP P E P PP + P P P P P P
Sbjct: 664 --SVLTPPPLGAP-----EAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVK 716
Query: 459 LPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAP 514
V+P P L + A P AL P P P P + P P P
Sbjct: 717 AEVSPHGAPALSNGPQTQAQLLQPL--QALQTQLLPQALPPPQPQLQPPPSPQQMP 770
Score = 44.3 bits (103), Expect = 4e-04
Identities = 60/239 (25%), Positives = 84/239 (35%), Gaps = 34/239 (14%)
Query: 57 PPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAG 116
PP + V + +T P + P+PV PP P P T +P P K +
Sbjct: 554 PPKVEVSPVLRPPITTSPPVPQEPAPVPSPPR--------APTPPSTPVPLPEKRRSILR 605
Query: 117 TPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPP------LET 170
P R L PP PPP P S + + RAP QF P E+
Sbjct: 606 EPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAP-QFTPSEAHLKIYES 664
Query: 171 WKPPPPLPSERQPADRRITPALATPASPP------TESQAGPRNQGQTAGRARGGAPPHA 224
PPPL + P + PA +PA P T + PR + PH
Sbjct: 665 VLTPPPLGAPEAP-EPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG 723
Query: 225 G---------EGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSL--AAKASLGGGG 272
+ ++ QP + LL + +P L PP + + KA + G G
Sbjct: 724 APALSNGPQTQAQLLQPLQALQ-TQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVG 781
Score = 42.4 bits (98), Expect = 0.001
Identities = 103/459 (22%), Positives = 134/459 (29%), Gaps = 151/459 (32%)
Query: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKW 111
P ++ PP L P P SP LP SP PPP + +PPP T K
Sbjct: 420 PSTSPPPPLCPPPPPPVSPPPLP------SPP-PPPAQEEQEESPPPVVPATC---SRKR 469
Query: 112 QKPAGTPVPRIRRLLEASHRG--------------QGDPPSLRPLKPPPPP------RQL 151
+P TP R R EA+ G G PP P P RQ
Sbjct: 470 GRPPLTPSQRAER--EAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQF 527
Query: 152 SVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATP--ASPPTESQAGPRNQ 209
+ R+ P PP P + + ++P L P SPP + P
Sbjct: 528 IMPVVSARSSRVIKTPRRFMDEDPPKPPKVE-----VSPVLRPPITTSPPVPQEPAP--- 579
Query: 210 GQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLG 269
+PP A E S+L + TF+
Sbjct: 580 --------VPSPPRAPTPPSTPVPLPEKRRSILREPTFR--------------------- 610
Query: 270 GGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAP 329
+ + ++ P PP A P PP AP
Sbjct: 611 ---------------WTSLTRELPPPPPAPPP------------------PPAPSPPPAP 637
Query: 330 ASQAR---ALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGP 386
A+ +R L P +T ++ V P +GAP
Sbjct: 638 ATSSRRPLLLRAPQFTPSEAHLKIYESVLTPP-------------PLGAPEAPE------ 678
Query: 387 WGSPPPPPEQIHSAPGPRRPAPA-LLAPPTF--IFPAPTNGEPMRPGPPGLQELPP---- 439
PPP + + P PR L+ P F + P E G P L P
Sbjct: 679 --PEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQ 736
Query: 440 ------------LPPPTPPPTLQPPALQPTPLP-VAPPL 465
LP PPP P LQP P P PPL
Sbjct: 737 LLQPLQALQTQLLPQALPPP---QPQLQPPPSPQQMPPL 772
Score = 33.9 bits (76), Expect = 0.48
Identities = 45/160 (28%), Positives = 56/160 (35%), Gaps = 40/160 (25%)
Query: 431 PPGLQELPPLPPPTPPPTLQPPA-----------LQPTPLPVAP------PLTPGLGHKE 473
PP L ++ P PP TP L+ P AP P TP +
Sbjct: 163 PPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTP----RR 218
Query: 474 SALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRA 533
S P PA P QA + A A T+ +P PP P P+K +T GS
Sbjct: 219 SRGRPPGRPA-GPCRRKQQAVVVAEA-AVTIPKPEPP-----PPVVPVKHQT----GSWK 267
Query: 534 ARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTG 573
+ G GP SS GG GG G + G
Sbjct: 268 CK--------EGPGPGPGTPRRGGQSSRGGRGGRGRGRGG 299
Score = 33.1 bits (74), Expect = 0.83
Identities = 44/150 (29%), Positives = 58/150 (38%), Gaps = 31/150 (20%)
Query: 19 PSDRAPDSRRTSLVE-PEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQASP------- 70
P A SRR L+ P+ T L + TPP L P P+ P
Sbjct: 634 PPAPATSSRRPLLLRAPQFTPSEAHLKI-----YESVLTPPPLGAPEAPEPEPPPADDSP 688
Query: 71 ---------STLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPR 121
T L+L R +PV+ P +A +P APA L GP Q A P
Sbjct: 689 AEPEPRAVGRTNHLSLPRFAPVVTTPVKAEV--SPHGAPA--LSNGP---QTQAQLLQP- 740
Query: 122 IRRLLEASHRGQGDPPSLRPLKPPPPPRQL 151
+ L+ Q PP L+PPP P+Q+
Sbjct: 741 -LQALQTQLLPQALPPPQPQLQPPPSPQQM 769
Score = 29.6 bits (65), Expect = 9.1
Identities = 32/107 (29%), Positives = 40/107 (37%), Gaps = 24/107 (22%)
Query: 357 PDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTF 416
P GP R G G G PR A P PE+ S + + P++
Sbjct: 1042 PPGPRR-------GAGAGGPREEVVA--------HPGPEEQDSLLQRKSARRCVKQRPSY 1086
Query: 417 -IFPAPTNGEPMRPGPPGLQELPP----LPPPTPPPTLQP--PALQP 456
IF + EP GPP + P LP P P +P P LQP
Sbjct: 1087 DIFEDSDDSEP--GGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQP 1131
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,583,462
Number of Sequences: 37866
Number of extensions: 3666723
Number of successful extensions: 85288
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1107
Number of HSP's successfully gapped in prelim test: 2690
Number of HSP's that attempted gapping in prelim test: 21824
Number of HSP's gapped (non-prelim): 28835
length of query: 652
length of database: 18,247,518
effective HSP length: 109
effective length of query: 543
effective length of database: 14,120,124
effective search space: 7667227332
effective search space used: 7667227332
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.