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Search of human proteins with 122937283
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937283 6720455I24Rik homolog [Homo sapiens]
(1413 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937283 6720455I24Rik homolog [Homo sapiens] 3047 0.0
gi|148833508 notch1 preproprotein [Homo sapiens] 470 e-132
gi|24041035 notch 2 preproprotein [Homo sapiens] 447 e-125
gi|134244285 Notch homolog 3 [Homo sapiens] 443 e-124
gi|55770876 notch4 preproprotein [Homo sapiens] 427 e-119
gi|4557679 jagged 1 precursor [Homo sapiens] 387 e-107
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 373 e-103
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 358 2e-98
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 341 3e-93
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 280 7e-75
gi|134268640 tectorin alpha precursor [Homo sapiens] 270 7e-72
gi|112420992 crumbs homolog 2 [Homo sapiens] 256 8e-68
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 234 3e-61
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 232 2e-60
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 231 5e-60
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 218 2e-56
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 209 1e-53
gi|153946395 tenascin C precursor [Homo sapiens] 207 8e-53
gi|66346695 fibrillin 2 precursor [Homo sapiens] 206 2e-52
gi|110735443 delta-like 1 [Homo sapiens] 205 3e-52
gi|110347437 latent transforming growth factor beta binding prot... 201 3e-51
gi|110347412 latent transforming growth factor beta binding prot... 201 3e-51
gi|110347431 latent transforming growth factor beta binding prot... 201 3e-51
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 201 5e-51
gi|56237021 fibrillin 3 precursor [Homo sapiens] 197 6e-50
gi|148886654 polydom [Homo sapiens] 197 8e-50
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 196 2e-49
gi|24430141 fibrillin 1 precursor [Homo sapiens] 192 2e-48
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 191 6e-48
gi|11321571 slit homolog 3 [Homo sapiens] 171 5e-42
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 3047 bits (7900), Expect = 0.0
Identities = 1413/1413 (100%), Positives = 1413/1413 (100%)
Query: 1 MRHGVAWALLVAAALGLGARGVRGAVALADFYPFGAERGDAVTPKQDDGGSGLRPLSVPF 60
MRHGVAWALLVAAALGLGARGVRGAVALADFYPFGAERGDAVTPKQDDGGSGLRPLSVPF
Sbjct: 1 MRHGVAWALLVAAALGLGARGVRGAVALADFYPFGAERGDAVTPKQDDGGSGLRPLSVPF 60
Query: 61 PFFGAEHSGLYVNNNGIISFLKEVSQFTPVAFPIAKDRCVVAAFWADVDNRRAGDVYYRE 120
PFFGAEHSGLYVNNNGIISFLKEVSQFTPVAFPIAKDRCVVAAFWADVDNRRAGDVYYRE
Sbjct: 61 PFFGAEHSGLYVNNNGIISFLKEVSQFTPVAFPIAKDRCVVAAFWADVDNRRAGDVYYRE 120
Query: 121 ATDPAMLRRATEDVRHYFPELLDFNATWVFVATWYRVTFFGGSSSSPVNTFQTVLITDGK 180
ATDPAMLRRATEDVRHYFPELLDFNATWVFVATWYRVTFFGGSSSSPVNTFQTVLITDGK
Sbjct: 121 ATDPAMLRRATEDVRHYFPELLDFNATWVFVATWYRVTFFGGSSSSPVNTFQTVLITDGK 180
Query: 181 LSFTIFNYESIVWTTGTHASSGGNATGLGGIAAQAGFNAGDGQRYFSIPGSRTADMAEVE 240
LSFTIFNYESIVWTTGTHASSGGNATGLGGIAAQAGFNAGDGQRYFSIPGSRTADMAEVE
Sbjct: 181 LSFTIFNYESIVWTTGTHASSGGNATGLGGIAAQAGFNAGDGQRYFSIPGSRTADMAEVE 240
Query: 241 TTTNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCL 300
TTTNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCL
Sbjct: 241 TTTNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCL 300
Query: 301 SGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQH 360
SGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQH
Sbjct: 301 SGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQH 360
Query: 361 GGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGL 420
GGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGL
Sbjct: 361 GGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGL 420
Query: 421 RCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRC 480
RCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRC
Sbjct: 421 RCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRC 480
Query: 481 LGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS 540
LGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS
Sbjct: 481 LGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS 540
Query: 541 LPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGG 600
LPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGG
Sbjct: 541 LPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGG 600
Query: 601 EYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSP 660
EYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSP
Sbjct: 601 EYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSP 660
Query: 661 CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA 720
CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA
Sbjct: 661 CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA 720
Query: 721 LYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCS 780
LYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCS
Sbjct: 721 LYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCS 780
Query: 781 TGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQH 840
TGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQH
Sbjct: 781 TGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQH 840
Query: 841 GGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGE 900
GGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGE
Sbjct: 841 GGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGE 900
Query: 901 DCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDR 960
DCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDR
Sbjct: 901 DCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDR 960
Query: 961 TRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTAST 1020
TRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTAST
Sbjct: 961 TRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTAST 1020
Query: 1021 ISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTL 1080
ISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTL
Sbjct: 1021 ISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTL 1080
Query: 1081 SGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVINV 1140
SGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVINV
Sbjct: 1081 SGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVINV 1140
Query: 1141 TTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLYIITSPRD 1200
TTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLYIITSPRD
Sbjct: 1141 TTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLYIITSPRD 1200
Query: 1201 GADRRWHQGGHHPRVLKNRPPPARLPELRLLNDHSAPETPTQPPRFSELVDGRGRVSARF 1260
GADRRWHQGGHHPRVLKNRPPPARLPELRLLNDHSAPETPTQPPRFSELVDGRGRVSARF
Sbjct: 1201 GADRRWHQGGHHPRVLKNRPPPARLPELRLLNDHSAPETPTQPPRFSELVDGRGRVSARF 1260
Query: 1261 GGSPSKAATVRSQPTASAQLENMEEAPKRVSLALQLPEHGSKDIGNVPGNCSENPCQNGG 1320
GGSPSKAATVRSQPTASAQLENMEEAPKRVSLALQLPEHGSKDIGNVPGNCSENPCQNGG
Sbjct: 1261 GGSPSKAATVRSQPTASAQLENMEEAPKRVSLALQLPEHGSKDIGNVPGNCSENPCQNGG 1320
Query: 1321 TCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCHHVYKRVYR 1380
TCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCHHVYKRVYR
Sbjct: 1321 TCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCHHVYKRVYR 1380
Query: 1381 VHQDICFKESCESTSLKKTPNRKQSKSQTLEKS 1413
VHQDICFKESCESTSLKKTPNRKQSKSQTLEKS
Sbjct: 1381 VHQDICFKESCESTSLKKTPNRKQSKSQTLEKS 1413
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 470 bits (1210), Expect = e-132
Identities = 245/675 (36%), Positives = 326/675 (48%), Gaps = 62/675 (9%)
Query: 274 ALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSF 333
A PC + G C+D Y C+C G+TG C+++++ECA PC NGGTC GIN F
Sbjct: 646 ASSPC-DSGTCLDKI----DGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGF 700
Query: 334 RCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSP 393
C+CP G+ PTC + + C++ C HG C+ C C G++G C+++ ++C
Sbjct: 701 TCRCPEGYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECES 759
Query: 394 DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVC 453
+PC+NGG+C D+ Y C C E F G C+T + C S PC N GTC+D GY C
Sbjct: 760 NPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINE----CASNPCLNQGTCIDDVAGYKC 815
Query: 454 ECPEGFMGLDCRERVPDDCE---CRNGGRCLGAN---TTLCQCPLGFFGLLCEFEITAMP 507
C + G C E V C CRNGG C + + C CP G+ G CE +I
Sbjct: 816 NCLLPYTGATC-EVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINEC- 873
Query: 508 CNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS--PCDSDPCFNGGSCDAHDDSYTC 565
+ + C G C G Y C C ++ + C +PC NGGSC ++ C
Sbjct: 874 --VLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFC 931
Query: 566 ECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCAS 625
+C GF G CE+ C+S PCRNG C + Y C+CP F+G HCE PD C
Sbjct: 932 DCLPGFRGTFCEEDINE-CASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPD-CTE 989
Query: 626 GPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQA 685
C NGGTC I + C CPPGF+G +C+ + C PC++GGTC+D + C C
Sbjct: 990 SSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQ 1049
Query: 686 GYMGRRCQAEV---DCGPPEEVKHATLRFNGTRL----GAVALY------ACDRGYSLSA 732
GY G CQ V D P + R G LY +C+
Sbjct: 1050 GYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQG 1109
Query: 733 PSRIRVCQPHGVWSEPPQ--------------CLE-IDECRSQPCLHGGSCQDRVAGYLC 777
R+CQ G+ + C + +DEC PC +G +C D + GY C
Sbjct: 1110 VDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSC 1169
Query: 778 LCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACD--- 834
C GY G +C E DEC +HPC+NGG+C +LP Y C CP G GVHCE VD C+
Sbjct: 1170 KCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPV 1229
Query: 835 -----SSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRG--YCLASNG 887
S C + G C G Y C CP F G CE + C S+PC RG C+
Sbjct: 1230 DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVN 1289
Query: 888 SHSCTCKVGYTGEDC 902
C C+ G+TG C
Sbjct: 1290 DFHCECRAGHTGRRC 1304
Score = 464 bits (1195), Expect = e-130
Identities = 248/657 (37%), Positives = 321/657 (48%), Gaps = 55/657 (8%)
Query: 274 ALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTC--THGIN 331
A PCLN G CIDD Y C+CL +TG C + + CA PC+NGG C +
Sbjct: 796 ASNPCLNQGTCIDDVA----GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYE 851
Query: 332 SFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDC 391
SF C CP G+ G TCE + C C+HG CQ +G C CQAGY+G CE D+DDC
Sbjct: 852 SFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDC 911
Query: 392 SPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGY 451
P+PC NGGSC D + C C F+G CE + C S PC NG C D Y
Sbjct: 912 RPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINE----CASDPCRNGANCTDCVDSY 967
Query: 452 VCECPEGFMGLDCRERVPDDCE--CRNGGRCL-GANTTLCQCPLGFFGLLCEFEITAMPC 508
C CP GF G+ C PD E C NGG C+ G N+ C CP GF G C+ ++ C
Sbjct: 968 TCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNE--C 1025
Query: 509 NMNTQCPDGGYCMEHGGSYLCVCHTDHNASH--SLPSPCDSDPCFNGGSCDAHDDSYTCE 566
+ + C GG C + GSY C C + + +L CDS PC NGG C Y CE
Sbjct: 1026 D-SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCE 1084
Query: 567 CPRGFHGKHCE---------KARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEI 617
CP G+ G +C+ R + + C++GG C +AG +HC C +TG +CE
Sbjct: 1085 CPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE- 1143
Query: 618 GKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDT 677
D C+ PC NG TC Y+G Y C C G+ G +C C PC NGGTC D
Sbjct: 1144 DLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPN 1203
Query: 678 DFFCHCQAGYMGRRCQAEVD-CGPP-EEVKHATLRFN-GTRLGAVALYACDRGYSLSAPS 734
+ C C G G C+ VD C PP + V + FN GT + V Y+C
Sbjct: 1204 TYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC---------- 1253
Query: 735 RIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGS--CQDRVAGYLCLCSTGYEGAHCELER 792
C P V +++EC S PC G+ C RV + C C G+ G CE
Sbjct: 1254 ---TCPPGFVGERCEG--DVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI 1308
Query: 793 DECRAHPCRNGGSCR---NLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 849
+ C+ PC+NGG+C N ++C+CPAGF G CE + C S C +GG C SG
Sbjct: 1309 NGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPR 1368
Query: 850 AYLCVCPESFFGYHCE-TVSDPCF-SSPCGGRGYCLASNGS--HSCTCKVGYTGEDC 902
+ C+C F G C+ S PC +PC +G C ++ S + C C + G C
Sbjct: 1369 SPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
Score = 461 bits (1187), Expect = e-129
Identities = 236/648 (36%), Positives = 324/648 (50%), Gaps = 50/648 (7%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C T C A PCL+ G+C+D + C C +GFTG C DV+ECAS PC+NG
Sbjct: 487 CEVNTDEC-ASSPCLHNGRCLDKI----NEFQCECPTGFTGHLCQYDVDECASTPCKNGA 541
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
C G N++ C C G+ G CE CD C H G C+ + C+C+ GYTG C
Sbjct: 542 KCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHC 600
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
E ++++CS PC +GG+C D Y C C + G CE D C S+PC + GTC
Sbjct: 601 ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEIN----LDDCASSPC-DSGTC 655
Query: 445 VDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCL-GANTTLCQCPLGFFGLLCE 500
+D GY C C G+ G C + D+C C NGG C G N C+CP G+ C
Sbjct: 656 LDKIDGYECACEPGYTGSMCNINI-DECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCL 714
Query: 501 FEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS--LPSPCDSDPCFNGGSCDA 558
E+ CN N C G C + Y C C + ++ + C+S+PC NGG+C
Sbjct: 715 SEVNE--CNSNP-CVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKD 770
Query: 559 HDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIG 618
Y C C GF G +C+ + C+S PC N GTC + Y C+C +TG CE+
Sbjct: 771 MTSGYVCTCREGFSGPNCQ-TNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVV 829
Query: 619 KPDSCASGPCHNGGTCFHY--IGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRD 676
CA PC NGG C + C CP G+ G+ CE+ + C SPC +G +C++
Sbjct: 830 LAP-CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTH 888
Query: 677 TDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRI 736
+ CHCQAGY GR C+ ++D P + G+ + CD
Sbjct: 889 GGYRCHCQAGYSGRNCETDIDDCRPNPCHNG-----GSCTDGINTAFCD----------- 932
Query: 737 RVCQP--HGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDE 794
C P G + E +I+EC S PC +G +C D V Y C C G+ G HCE +
Sbjct: 933 --CLPGFRGTFCEE----DINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPD 986
Query: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCV 854
C C NGG+C + ++ C CP GF G +C+ +V+ CDS PC HGG C+ G G+Y C
Sbjct: 987 CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCT 1046
Query: 855 CPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
CP+ + G +C+ + C SSPC G C ++ + C C G+TG C
Sbjct: 1047 CPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC 1094
Score = 449 bits (1156), Expect = e-126
Identities = 258/773 (33%), Positives = 350/773 (45%), Gaps = 170/773 (21%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQC 337
C NGG C + + Y C C++G+TG C ++++CAS C +G TC + SF C+C
Sbjct: 306 CQNGGTCHNT----HGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCEC 361
Query: 338 PAGFGGPTCETAQSPCDTKECQHGGQCQVE--NGSAVCVCQAGYTGAACEMDVDDCS--P 393
P G G C + C + C G C NG A+C C +GYTG AC DVD+CS
Sbjct: 362 PHGRTGLLCHLNDA-CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGA 420
Query: 394 DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVC 453
+PC + G C++ +G++ C C + + G RCE + C+S PC N TC+D + C
Sbjct: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCEID----VNECVSNPCQNDATCLDQIGEFQC 476
Query: 454 ECPEGFMGLDCRERVPDDCE---CRNGGRCLGA-NTTLCQCPLGFFGLLCEFEITAMPCN 509
C G+ G+ C D+C C + GRCL N C+CP GF G LC++++
Sbjct: 477 ICMPGYEGVHCEVNT-DECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECA-- 533
Query: 510 MNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS--PCDSDPCFNGGSCDAHDDSYTCEC 567
+T C +G C++ +Y CVC + +H CD DPC + GSC ++TC C
Sbjct: 534 -STPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLC 591
Query: 568 PRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPD------ 621
G+ G HCE + CSS PCR+GGTC++ Y C C TG +CEI D
Sbjct: 592 RPGYTGHHCE-TNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPC 650
Query: 622 ------------------------------SCASGPCHNGGTC--------------FH- 636
CA PCHNGGTC +H
Sbjct: 651 DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHD 710
Query: 637 ----------------------YIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCED 674
+ YKCDC PG+SG +C+I + C +PCVNGGTC+D
Sbjct: 711 PTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKD 770
Query: 675 RDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACD-----RGYS 729
+ + C C+ G+ G CQ ++ E GT + VA Y C+ G +
Sbjct: 771 MTSGYVCTCREGFSGPNCQTNIN-----ECASNPCLNQGTCIDDVAGYKCNCLLPYTGAT 825
Query: 730 LS------APSRIR----------------VCQPHGVWSEPPQCLEIDECRSQPCLHGGS 767
APS R VC P G W ++I+EC PC HG S
Sbjct: 826 CEVVLAPCAPSPCRNGGECRQSEDYESFSCVC-PTG-WQGQTCEVDINECVLSPCRHGAS 883
Query: 768 CQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRN---------LPG------- 811
CQ+ GY C C GY G +CE + D+CR +PC NGGSC + LPG
Sbjct: 884 CQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCE 943
Query: 812 ----------------------AYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 849
+Y C CPAGF G+HCE C S C +GG C G
Sbjct: 944 EDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGIN 1003
Query: 850 AYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
++ C+CP F G +C+ + C S PC G C GS+ CTC GYTG +C
Sbjct: 1004 SFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNC 1056
Score = 447 bits (1151), Expect = e-125
Identities = 235/697 (33%), Positives = 324/697 (46%), Gaps = 92/697 (13%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C + C A PC NG KC+D G +YTC C G+TG C +D++EC PC G
Sbjct: 525 CQYDVDEC-ASTPCKNGAKCLD----GPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG- 578
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
+C G+ +F C C G+ G CET + C ++ C+HGG CQ + + +C C G TG C
Sbjct: 579 SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
E+++DDC+ PC + G+C+D + Y C C + G C D C PCHNGGTC
Sbjct: 639 EINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINI----DECAGNPCHNGGTC 693
Query: 445 VDADQGYVCECPEGFMGLDCRERVPD--------------------DCE----------- 473
D G+ C CPEG+ C V + DC+
Sbjct: 694 EDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDIN 753
Query: 474 --------CRNGGRCLGANTT-LCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHG 524
C NGG C + +C C GF G C+ I N C + G C++
Sbjct: 754 NNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN---PCLNQGTCIDDV 810
Query: 525 GSYLCVCHTDHNAS--HSLPSPCDSDPCFNGGSCDAHDD--SYTCECPRGFHGKHCEKAR 580
Y C C + + + +PC PC NGG C +D S++C CP G+ G+ CE
Sbjct: 811 AGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCE-VD 869
Query: 581 PHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGK 640
+ C PCR+G +C+ G Y C C ++GR+CE D C PCHNGG+C I
Sbjct: 870 INECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDI-DDCRPNPCHNGGSCTDGINT 928
Query: 641 YKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEV-DCG 699
CDC PGF G CE + C PC NG C D + C C AG+ G C+ DC
Sbjct: 929 AFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDC- 987
Query: 700 PPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRS 759
++ GT + + + C +C P S +++EC S
Sbjct: 988 -----TESSCFNGGTCVDGINSFTC-------------LCPPGFTGSYCQH--DVNECDS 1027
Query: 760 QPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPA 819
QPCLHGG+CQD Y C C GY G +C+ C + PC+NGG C Y C CP+
Sbjct: 1028 QPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPS 1087
Query: 820 GFVGVHCETEVDACDSSP----------CQHGGRCESGGGAYLCVCPESFFGYHCETVSD 869
G+ G++C+ +C+ + CQHGG C G + C C + G +CE + D
Sbjct: 1088 GWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVD 1147
Query: 870 PCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
C SPC C G +SC C GY G +C++E+
Sbjct: 1148 ECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1184
Score = 436 bits (1122), Expect = e-122
Identities = 219/646 (33%), Positives = 319/646 (49%), Gaps = 53/646 (8%)
Query: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
PC NGG C TG+ ++ C+CL GFTG+ C ++++C C+NGG C G+N++ C+
Sbjct: 226 PCQNGGTCRP---TGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCR 282
Query: 337 CPAGFGGPTCETAQSPCDT--KECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPD 394
CP + G C C CQ+GG C +G CVC G+TG C ++DDC+
Sbjct: 283 CPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASA 342
Query: 395 PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVD--ADQGYV 452
C +G +C D V ++ C C GL C D AC+S PC+ G C + +
Sbjct: 343 ACFHGATCHDRVASFYCECPHGRTGLLCHLND-----ACISNPCNEGSNCDTNPVNGKAI 397
Query: 453 CECPEGFMGLDCRERVPDDCE-----CRNGGRCLGANTTL-CQCPLGFFGLLCEFEITAM 506
C CP G+ G C + V D+C C + G+C+ + CQC G+ G CE ++
Sbjct: 398 CTCPSGYTGPACSQDV-DECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC 456
Query: 507 PCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSP--CDSDPCFNGGSCDAHDDSYT 564
N C + C++ G + C+C + H + C S PC + G C + +
Sbjct: 457 VSN---PCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQ 513
Query: 565 CECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCA 624
CECP GF G C+ C+S PC+NG C + Y C C +TG HCE+ D C
Sbjct: 514 CECPTGFTGHLCQYDVDE-CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDI-DECD 571
Query: 625 SGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ 684
PCH G +C + + C C PG++G HCE + C PC +GGTC+DRD + C C
Sbjct: 572 PDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCL 630
Query: 685 AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALY--ACDRGYSLSAPSRIRVCQPH 742
G G C+ +D +GT L + Y AC+ GY+ S +C
Sbjct: 631 KGTTGPNCEINLDDCASSPCD------SGTCLDKIDGYECACEPGYTGS------MCN-- 676
Query: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRN 802
+ IDEC PC +GG+C+D + G+ C C GY C E +EC ++PC +
Sbjct: 677 ---------INIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVH 727
Query: 803 GGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGY 862
G +CR+ Y C C G+ G +C+ + C+S+PC +GG C+ Y+C C E F G
Sbjct: 728 G-ACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGP 786
Query: 863 HCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
+C+T + C S+PC +G C+ + C C + YTG C L P
Sbjct: 787 NCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAP 832
Score = 424 bits (1089), Expect = e-118
Identities = 243/707 (34%), Positives = 318/707 (44%), Gaps = 115/707 (16%)
Query: 271 VCLALRP---------------CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNEC 315
+CLAL P CLNGGKC N + C C F G RC D N C
Sbjct: 9 LCLALLPALAARGPRCSQPGETCLNGGKC----EAANGTEACVCGGAFVGPRCQ-DPNPC 63
Query: 316 ASQPCQNGGTC----THGINSFRCQCPAGFGGPTCET----------------------- 348
S PC+N GTC G+ + C C GF GP C T
Sbjct: 64 LSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLT 123
Query: 349 ----------------AQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCS 392
PC + C +GGQC S +C C + G C DV++C
Sbjct: 124 EYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECG 183
Query: 393 PDP--CLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC-VDADQ 449
P C +GG+C + VG+Y C+C G CE P C +PC NGGTC D
Sbjct: 184 QKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP----CSPSPCQNGGTCRPTGDV 239
Query: 450 GYVCECPEGFMGLDCRERVPDDC---ECRNGGRCL-GANTTLCQCPLGFFGLLCEFEITA 505
+ C C GF G +C E + DDC C+NGG C+ G NT C+CP + G C ++
Sbjct: 240 THECACLPGFTGQNCEENI-DDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDE 298
Query: 506 MPCNMNTQCPDGGYCMEHGGSYLCVC---HTDHNASHSLPSPCDSDPCFNGGSCDAHDDS 562
M C +GG C G Y CVC T + S ++ C S CF+G +C S
Sbjct: 299 CQL-MPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENI-DDCASAACFHGATCHDRVAS 356
Query: 563 YTCECPRGFHGKHCEKARPHL---CSSGPCRNGGTC--KEAGGEYHCSCPYRFTGRHCEI 617
+ CECP G G C HL C S PC G C G+ C+CP +TG C
Sbjct: 357 FYCECPHGRTGLLC-----HLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACS- 410
Query: 618 GKPDSCASG--PCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDR 675
D C+ G PC + G C + +G ++C C G++G CEI + C +PC N TC D+
Sbjct: 411 QDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQ 470
Query: 676 DTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSR 735
+F C C GY G C+ D E + NG L + + C+ +
Sbjct: 471 IGEFQCICMPGYEGVHCEVNTD-----ECASSPCLHNGRCLDKINEFQCECPTGFTG--- 522
Query: 736 IRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDEC 795
+CQ ++DEC S PC +G C D Y C+C+ GY G HCE++ DEC
Sbjct: 523 -HLCQ-----------YDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDEC 570
Query: 796 RAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVC 855
PC + GSC++ + C C G+ G HCET ++ C S PC+HGG C+ AYLC C
Sbjct: 571 DPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFC 629
Query: 856 PESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
+ G +CE D C SSPC G CL + C C+ GYTG C
Sbjct: 630 LKGTTGPNCEINLDDCASSPCDS-GTCLDKIDGYECACEPGYTGSMC 675
Score = 416 bits (1068), Expect = e-115
Identities = 239/668 (35%), Positives = 308/668 (46%), Gaps = 56/668 (8%)
Query: 270 SVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHG 329
+ CL PC NGG C D +T Y C C G++G+ C + CAS PC NGG C
Sbjct: 104 NACLT-NPCRNGGTC--DLLTLT-EYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPF 158
Query: 330 INSFRCQCPAGFGGPTCETAQSPCDTKE--CQHGGQCQVENGSAVCVCQAGYTGAACEMD 387
S+ C CP F GPTC + C K C+HGG C E GS CVC+A +TG CE
Sbjct: 159 EASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERP 218
Query: 388 VDDCSPDPCLNGGSCVDLVGNYT--CLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCV 445
CSP PC NGG+C G+ T C C F G CE D C C NGG CV
Sbjct: 219 YVPCSPSPCQNGGTCRP-TGDVTHECACLPGFTGQNCEEN----IDDCPGNNCKNGGACV 273
Query: 446 DADQGYVCECPEGFMGLDCRERVPDDCE-----CRNGGRCLGANTTL-CQCPLGFFGLLC 499
D Y C CP + G C E V D+C+ C+NGG C + C C G+ G C
Sbjct: 274 DGVNTYNCRCPPEWTGQYCTEDV-DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDC 332
Query: 500 EFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC-HTDHNASHSLPSPCDSDPCFNGGSCDA 558
I + C G C + S+ C C H L C S+PC G +CD
Sbjct: 333 SENIDDC---ASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDT 389
Query: 559 H--DDSYTCECPRGFHGKHCEKARPHLCSSG--PCRNGGTCKEAGGEYHCSCPYRFTGRH 614
+ + C CP G+ G C + CS G PC + G C G + C C +TG
Sbjct: 390 NPVNGKAICTCPSGYTGPACSQDVDE-CSLGANPCEHAGKCINTLGSFECQCLQGYTGPR 448
Query: 615 CEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCED 674
CEI + C S PC N TC IG+++C C PG+ G HCE+ C SPC++ G C D
Sbjct: 449 CEI-DVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLD 507
Query: 675 RDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYS-LSAP 733
+ +F C C G+ G CQ +VD K+ +G C GY+
Sbjct: 508 KINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN---TYTCVCTEGYTGTHCE 564
Query: 734 SRIRVCQP---------HGVWSEPPQC----------LEIDECRSQPCLHGGSCQDRVAG 774
I C P GV + C I+EC SQPC HGG+CQDR
Sbjct: 565 VDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNA 624
Query: 775 YLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACD 834
YLC C G G +CE+ D+C + PC + G+C + Y C C G+ G C +D C
Sbjct: 625 YLCFCLKGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECA 683
Query: 835 SSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCK 894
+PC +GG CE G + C CPE + C + + C S+PC G C S + C C
Sbjct: 684 GNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPC-VHGACRDSLNGYKCDCD 742
Query: 895 VGYTGEDC 902
G++G +C
Sbjct: 743 PGWSGTNC 750
Score = 294 bits (753), Expect = 4e-79
Identities = 206/645 (31%), Positives = 268/645 (41%), Gaps = 95/645 (14%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C + C A PC NG C D CV SYTC+C +GF+G C + +C C NGG
Sbjct: 942 CEEDINEC-ASDPCRNGANCTD-CVD---SYTCTCPAGFSGIHCENNTPDCTESSCFNGG 996
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
TC GINSF C CP GF G C+ + CD++ C HGG CQ GS C C GYTG C
Sbjct: 997 TCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNC 1056
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDAC------LSAPC 438
+ V C PC NGG C Y C C + GL C+ A ++ C
Sbjct: 1057 QNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLC 1116
Query: 439 HNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRC---LGANTTLCQCPL 492
+GG CVDA + C C G+ G C + V D+C C+NG C LG + C+C
Sbjct: 1117 QHGGLCVDAGNTHHCRCQAGYTGSYCEDLV-DECSPSPCQNGATCTDYLGGYS--CKCVA 1173
Query: 493 GFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC-------HTDHNASHSLPSPC 545
G+ G+ C EI ++ C +GG C++ +Y C C H + N P P
Sbjct: 1174 GYHGVNCSEEIDEC---LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNP-PV 1229
Query: 546 D----SDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGT--CKEAG 599
D S CFN G+C Y+C CP GF G+ CE + C S PC GT C +
Sbjct: 1230 DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-GDVNECLSNPCDARGTQNCVQRV 1288
Query: 600 GEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTC---FHYIGKYKCDCPPGFSGRHCEI 656
++HC C TGR CE + C PC NGGTC + + C CP GF G CE
Sbjct: 1289 NDFHCECRAGHTGRRCE-SVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN 1347
Query: 657 APSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD--------------CGPPE 702
C C+NGGTC C C + G CQ C P
Sbjct: 1348 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTS 1407
Query: 703 EVKH----ATLRFNGTRLGAVALYACDRGYSLSAPSRI--RVCQPHGVWSEPPQCLEID- 755
E +FNG L + Y+ G P + C E P+C E
Sbjct: 1408 ESPFYRCLCPAKFNGL-LCHILDYSFGGGAGRDIPPPLIEEAC-------ELPECQEDAG 1459
Query: 756 ------ECRSQPC-LHGGSCQDRVAGYLCLCSTG------YEGAHCELERDECRAHPCR- 801
+C + C GG C C+ + HC+ +C + C
Sbjct: 1460 NKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCD---SQCNSAGCLF 1516
Query: 802 NGGSCRNLPG----AYVCRCPAGFVGVHCETEVDACDSSPCQHGG 842
+G C+ G Y C F HC+ C+S+ C+ G
Sbjct: 1517 DGFDCQRAEGQCNPLYDQYCKDHFSDGHCD---QGCNSAECEWDG 1558
Score = 247 bits (630), Expect = 7e-65
Identities = 141/407 (34%), Positives = 185/407 (45%), Gaps = 38/407 (9%)
Query: 514 CPDGGYCMEHGGSYLCVCHTDHNASHSL-PSPCDSDPCFNGGSCDAHDD----SYTCECP 568
C +GG C G+ CVC P+PC S PC N G+C D Y C C
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90
Query: 569 RGFHGKHCEKARPHLCSSGPCRNGGTCKEAG-GEYHCSCPYRFTGRHCEIGKPDSCASGP 627
GF G C + C + PCRNGGTC EY C CP ++G+ C+ + D CAS P
Sbjct: 91 LGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ--QADPCASNP 148
Query: 628 CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSP--CVNGGTCEDRDTDFFCHCQA 685
C NGG C + Y C CPP F G C + C + P C +GGTC + + C C+A
Sbjct: 149 CANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRA 208
Query: 686 GYMGRRCQAE-VDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGV 744
+ G C+ V C P T R G AC G++
Sbjct: 209 THTGPNCERPYVPCSPSPCQNGGTCRPTG---DVTHECACLPGFT--------------- 250
Query: 745 WSEPPQCLE-IDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP--CR 801
C E ID+C C +GG+C D V Y C C + G +C + DEC+ P C+
Sbjct: 251 ---GQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQ 307
Query: 802 NGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFG 861
NGG+C N G Y C C G+ G C +D C S+ C HG C ++ C CP G
Sbjct: 308 NGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTG 367
Query: 862 YHCETVSDPCFSSPCGGRGYCLAS--NGSHSCTCKVGYTGEDCAKEL 906
C ++D C S+PC C + NG CTC GYTG C++++
Sbjct: 368 LLCH-LNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDV 413
Score = 125 bits (314), Expect = 3e-28
Identities = 70/193 (36%), Positives = 95/193 (49%), Gaps = 10/193 (5%)
Query: 724 CDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQ--DR--VAGYLCLC 779
C G A + C G + P +C + + C S PC + G+C DR VA Y C C
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGP-RCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSC 89
Query: 780 STGYEGAHCELERDE-CRAHPCRNGGSCRNLP-GAYVCRCPAGFVGVHCETEVDACDSSP 837
+ G+ G C D C +PCRNGG+C L Y CRCP G+ G C+ + D C S+P
Sbjct: 90 ALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNP 148
Query: 838 CQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSP--CGGRGYCLASNGSHSCTCKV 895
C +GG+C +Y+C CP SF G C + C P C G C GS+ C C+
Sbjct: 149 CANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRA 208
Query: 896 GYTGEDCAKELFP 908
+TG +C + P
Sbjct: 209 THTGPNCERPYVP 221
Score = 51.2 bits (121), Expect = 7e-06
Identities = 21/34 (61%), Positives = 23/34 (67%), Gaps = 1/34 (2%)
Query: 1311 CSENPCQNGGTCVPGAD-AHSCDCGPGFKGRRCE 1343
CS +PCQNGGTC P D H C C PGF G+ CE
Sbjct: 222 CSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE 255
Score = 49.3 bits (116), Expect = 3e-05
Identities = 18/34 (52%), Positives = 22/34 (64%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
+C NPC NGG+C G + CDC PGF+G CE
Sbjct: 910 DCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCE 943
Score = 48.9 bits (115), Expect = 3e-05
Identities = 58/221 (26%), Positives = 78/221 (35%), Gaps = 60/221 (27%)
Query: 269 TSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTH 328
+S CL PC N G C + + +P Y C C + F G CH+
Sbjct: 1388 SSPCLGGNPCYNQGTC--EPTSESPFYRCLCPAKFNGLLCHI------------------ 1427
Query: 329 GINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDV 388
FGG P + C+ +CQ + G+ VC Q AC D
Sbjct: 1428 --------LDYSFGGGAGRDIPPPLIEEACEL-PECQEDAGNKVCSLQC--NNHACGWDG 1476
Query: 389 DDCS---PDPCLN------------GGSCVDLVGNYTCLCAEPFKGLRCETGD---HPVP 430
DCS DP N G C + CL F G C+ + +P+
Sbjct: 1477 GDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCL----FDGFDCQRAEGQCNPLY 1532
Query: 431 DACLSAPCHNGGTCVDADQGYVCECPE-GFMGLDCRERVPD 470
D C + + DQG C E + GLDC E VP+
Sbjct: 1533 DQY----CKDHFSDGHCDQG--CNSAECEWDGLDCAEHVPE 1567
Score = 46.6 bits (109), Expect = 2e-04
Identities = 19/38 (50%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Query: 1306 NVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
N P +C+E+ C NGGTCV G ++ +C C PGF G C+
Sbjct: 983 NTP-DCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQ 1019
Score = 45.4 bits (106), Expect = 4e-04
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 1311 CSENPCQNGGTC-VPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
C NPC+NGGTC + + C C PG+ G+ C+ A S PC + + P
Sbjct: 106 CLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCA---NGGQCLPFEASY 162
Query: 1370 VCH 1372
+CH
Sbjct: 163 ICH 165
Score = 43.5 bits (101), Expect = 0.001
Identities = 21/52 (40%), Positives = 24/52 (46%), Gaps = 3/52 (5%)
Query: 1303 DIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
DI N C NPC NGGTC + C C GF G C+ + S PC
Sbjct: 751 DINN--NECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPC 800
Score = 43.1 bits (100), Expect = 0.002
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 3/61 (4%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
C +PCQNGGTC+ + + C C G +G CE+ + P + K F G
Sbjct: 1187 CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCF---NNGT 1243
Query: 1371 C 1371
C
Sbjct: 1244 C 1244
Score = 42.7 bits (99), Expect = 0.002
Identities = 15/32 (46%), Positives = 19/32 (59%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
C+ NPC NGG C+P ++ C C P F G C
Sbjct: 144 CASNPCANGGQCLPFEASYICHCPPSFHGPTC 175
Score = 42.7 bits (99), Expect = 0.002
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 13/68 (19%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFP--VWE 1367
+C N C+NGG CV G + ++C C P + G+ CT E + P
Sbjct: 260 DCPGNNCKNGGACVDGVNTYNCRCPPEWTGQY-----------CTEDVDECQLMPNACQN 308
Query: 1368 GGVCHHVY 1375
GG CH+ +
Sbjct: 309 GGTCHNTH 316
Score = 42.4 bits (98), Expect = 0.003
Identities = 14/33 (42%), Positives = 20/33 (60%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C+ +PC+NG C D+++C C GF G CE
Sbjct: 949 CASDPCRNGANCTDCVDSYTCTCPAGFSGIHCE 981
Score = 41.6 bits (96), Expect = 0.005
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C NPCQN TC+ C C PG++G CE+ + S PC
Sbjct: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPC 499
Score = 41.6 bits (96), Expect = 0.005
Identities = 13/34 (38%), Positives = 21/34 (61%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C+ PC+NG C+ G + ++C C G+ G CE+
Sbjct: 532 CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV 565
Score = 41.6 bits (96), Expect = 0.005
Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 11/61 (18%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
CS +PCQNG TC +SC C G+ G C+ E + P GG
Sbjct: 1149 CSPSPCQNGATCTDYLGGYSCKCVAGYHGVN-----------CSEEIDECLSHPCQNGGT 1197
Query: 1371 C 1371
C
Sbjct: 1198 C 1198
Score = 41.2 bits (95), Expect = 0.007
Identities = 16/28 (57%), Positives = 17/28 (60%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C N GTCV +SC C PGF G RCE
Sbjct: 1238 CFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
Score = 39.7 bits (91), Expect = 0.021
Identities = 14/32 (43%), Positives = 18/32 (56%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
C+ NPC NGGTC G + +C C G+ C
Sbjct: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTC 713
Score = 39.7 bits (91), Expect = 0.021
Identities = 13/33 (39%), Positives = 18/33 (54%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C PC +GGTC G ++ C C G+ G C+
Sbjct: 1025 CDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 1057
Score = 38.9 bits (89), Expect = 0.035
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
NPC++ G C+ + C C G+ G RCE+ + VS PC
Sbjct: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPC 461
Score = 38.9 bits (89), Expect = 0.035
Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 11/61 (18%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
C+ NPC N GTC+ + C+C + G CE+ V PC P GG
Sbjct: 795 CASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEV----VLAPCA-------PSPCRNGGE 843
Query: 1371 C 1371
C
Sbjct: 844 C 844
Score = 38.9 bits (89), Expect = 0.035
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 3/48 (6%)
Query: 1299 HGSKDIGNVPGNCSENPCQNGGTCVPG---ADAHSCDCGPGFKGRRCE 1343
H + +V C PC+NGGTC A C C GF+G CE
Sbjct: 1299 HTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
Score = 38.5 bits (88), Expect = 0.046
Identities = 15/34 (44%), Positives = 20/34 (58%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
CS PC++GGTC +A+ C C G G CE+
Sbjct: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI 640
Score = 38.5 bits (88), Expect = 0.046
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 12/61 (19%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
C+ NPC +G C + + CDC PG+ G C++ +E ++ P GG
Sbjct: 720 CNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDIN-----------NNECESNPCVNGGT 767
Query: 1371 C 1371
C
Sbjct: 768 C 768
Score = 38.1 bits (87), Expect = 0.060
Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 12/62 (19%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
+C+ +PC +G TC+ D + C C PG+ G C + E P GG
Sbjct: 644 DCASSPCDSG-TCLDKIDGYECACEPGYTGSMCNIN-----------IDECAGNPCHNGG 691
Query: 1370 VC 1371
C
Sbjct: 692 TC 693
Score = 37.7 bits (86), Expect = 0.079
Identities = 15/36 (41%), Positives = 23/36 (63%), Gaps = 2/36 (5%)
Query: 1311 CSENPCQNGGTCVPGAD--AHSCDCGPGFKGRRCEL 1344
C+ +PC+NGG C D + SC C G++G+ CE+
Sbjct: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEV 868
Score = 37.0 bits (84), Expect = 0.13
Identities = 13/28 (46%), Positives = 16/28 (57%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
CQ+GG CV + H C C G+ G CE
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCE 1143
Score = 37.0 bits (84), Expect = 0.13
Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 14/74 (18%)
Query: 1300 GSKDIGNVPGNCSENPCQNGGT--CVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLF 1357
G + G+V C NPC GT CV + C+C G GRRCE +
Sbjct: 1261 GERCEGDV-NECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE-----------SVI 1308
Query: 1358 SETKAFPVWEGGVC 1371
+ K P GG C
Sbjct: 1309 NGCKGKPCKNGGTC 1322
Score = 36.2 bits (82), Expect = 0.23
Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 14/69 (20%)
Query: 1311 CSE--NPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEG 1368
CS+ C NGG C +C CG F G RC+ +S PC
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCK------------NA 71
Query: 1369 GVCHHVYKR 1377
G CH V +R
Sbjct: 72 GTCHVVDRR 80
Score = 36.2 bits (82), Expect = 0.23
Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 19/81 (23%)
Query: 1308 PGNCSENPCQNGGTC----VPGADAHSCDCGPGFKGRRC----ELACIKVSRPC------ 1353
P C PC+N GTC G ++C C GF G C + AC+ + PC
Sbjct: 60 PNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACL--TNPCRNGGTC 117
Query: 1354 ---TRLFSETKAFPVWEGGVC 1371
T + + P W G C
Sbjct: 118 DLLTLTEYKCRCPPGWSGKSC 138
Score = 36.2 bits (82), Expect = 0.23
Identities = 12/37 (32%), Positives = 20/37 (54%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACI 1347
C +PC+NGG C + C+C G+ G C++ +
Sbjct: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSV 1099
Score = 35.4 bits (80), Expect = 0.39
Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C+ +PC + G C+ + C+C GF G C+ + S PC
Sbjct: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPC 537
Score = 35.0 bits (79), Expect = 0.51
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C +PC++G +C + C C G+ GR CE
Sbjct: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCE 905
Score = 34.7 bits (78), Expect = 0.67
Identities = 16/43 (37%), Positives = 20/43 (46%), Gaps = 3/43 (6%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
C C NGGTC+ G + +C C F G C+ S PC
Sbjct: 1352 CGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQ---FPASSPC 1391
Score = 34.3 bits (77), Expect = 0.87
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
C +PC G +C G +C C PG+ G CE + S+PC
Sbjct: 570 CDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQPC 612
Score = 32.7 bits (73), Expect = 2.5
Identities = 13/29 (44%), Positives = 16/29 (55%)
Query: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
N CQNGGTC ++C C G+ G C
Sbjct: 304 NACQNGGTCHNTHGGYNCVCVNGWTGEDC 332
Score = 32.3 bits (72), Expect = 3.3
Identities = 14/44 (31%), Positives = 20/44 (45%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
+C+ C +G TC + C+C G G C L +S PC
Sbjct: 338 DCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPC 381
Score = 30.8 bits (68), Expect = 9.6
Identities = 13/33 (39%), Positives = 18/33 (54%), Gaps = 2/33 (6%)
Query: 1314 NPCQNGGTCVPGADA--HSCDCGPGFKGRRCEL 1344
NPC N GTC P +++ + C C F G C +
Sbjct: 1395 NPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1427
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 447 bits (1149), Expect = e-125
Identities = 227/637 (35%), Positives = 312/637 (48%), Gaps = 43/637 (6%)
Query: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
PC + GKC++ + ++ C CL G+ G RC +D+NEC S PCQN TC I F C
Sbjct: 426 PCEHAGKCVNT----DGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCL 481
Query: 337 CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPC 396
C GF G CE + C + C + GQC + C+C G+TG C++D+DDCS PC
Sbjct: 482 CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC 541
Query: 397 LNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECP 456
LNG C+D Y C CA F G+ CE D C PCH+G C D Y C C
Sbjct: 542 LNGAKCIDHPNGYECQCATGFTGVLCEENI----DNCDPDPCHHG-QCQDGIDSYTCICN 596
Query: 457 EGFMGLDCRERVPDDC---ECRNGGRCLG-ANTTLCQCPLGFFGLLCEFEITAMPCNMNT 512
G+MG C +++ D+C C N GRC+ N C C G G+ CE N
Sbjct: 597 PGYMGAICSDQI-DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCI 655
Query: 513 QCPDGGYCMEHGGSYLCVCH---TDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPR 569
G CM+ Y CVC T + + C S+PC G +C + + C CP
Sbjct: 656 H----GICMDGINRYSCVCSPGFTGQRCNIDIDE-CASNPCRKGATCINGVNGFRCICPE 710
Query: 570 GFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCH 629
G H C ++ + C S PC +G C Y C C + G +CE+ K + C S PC
Sbjct: 711 GPHHPSCY-SQVNECLSNPCIHGN-CTGGLSGYKCLCDAGWVGINCEVDK-NECLSNPCQ 767
Query: 630 NGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMG 689
NGGTC + + Y+C C GF G +C++ C +PC+N GTC D + + CHC Y G
Sbjct: 768 NGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTG 827
Query: 690 RRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPP 749
+ CQ + P ++A + + Y C +C P W
Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFES---YTC-------------LCAPG--WQGQR 869
Query: 750 QCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNL 809
++IDEC S+PC++ G C + Y+C C G+ G CE + D+C A+PC+NGGSC +
Sbjct: 870 CTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDG 929
Query: 810 PGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSD 869
+ C C GF G C+T+++ C S PC++GG C +Y C C F G HCE +
Sbjct: 930 VNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNIN 989
Query: 870 PCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
C S C G C+ S SC C VG+TG C E+
Sbjct: 990 ECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI 1026
Score = 444 bits (1142), Expect = e-124
Identities = 247/714 (34%), Positives = 340/714 (47%), Gaps = 96/714 (13%)
Query: 269 TSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNEC-ASQPCQNGGTCT 327
T CL+ PC NG C T ++C CL+GFTG++C DVNEC CQ+GGTC
Sbjct: 145 TDACLS-HPCANGSTC----TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL 199
Query: 328 HGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQC-QVENGSAVCVCQAGYTGAACEM 386
+ S++CQCP GF G C++ PC C +GG C Q + + C C G+ G+ CE
Sbjct: 200 NLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCER 259
Query: 387 DVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAP--CHNGGTC 444
++DDC C NGG CVD V Y C C + G C T D D CL P C NGGTC
Sbjct: 260 NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC-TED---VDECLLQPNACQNGGTC 315
Query: 445 VDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGANTTL-CQCPLGFFGLLCE 500
+ + GY C C G+ G DC E + DDC C G C+ + C CP G GLLC
Sbjct: 316 ANRNGGYGCVCVNGWSGDDCSENI-DDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCH 374
Query: 501 FEITAM--PCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLP-----SPCDSDPCFNG 553
+ + PC+ C G Y+C C + + + +S+PC +
Sbjct: 375 LDDACISNPCHKGALCDTNPL----NGQYICTCPQGYKGADCTEDVDECAMANSNPCEHA 430
Query: 554 GSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGR 613
G C D ++ CEC +G+ G CE + C S PC+N TC + G + C C F G
Sbjct: 431 GKCVNTDGAFHCECLKGYAGPRCE-MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGV 489
Query: 614 HCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCE 673
HCE+ + + C S PC N G C + +++C CPPGF+G C+I C +PC+NG C
Sbjct: 490 HCEL-EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCI 548
Query: 674 DRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHA---------TLRFNGTRLGAVALYAC 724
D + C C G+ G C+ +D P+ H T N +GA+
Sbjct: 549 DHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQI 608
Query: 725 DRGYSLSAPSRIRV----------CQP--HGVWSEPPQCLEIDECRSQPCLHGGSCQDRV 772
D YS + R CQP GV E + D+C S PC+H G C D +
Sbjct: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCE----INFDDCASNPCIH-GICMDGI 663
Query: 773 AGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRN------------------------ 808
Y C+CS G+ G C ++ DEC ++PCR G +C N
Sbjct: 664 NRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNE 723
Query: 809 --------------LPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCV 854
L G Y C C AG+VG++CE + + C S+PCQ+GG C++ Y C
Sbjct: 724 CLSNPCIHGNCTGGLSG-YKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCT 782
Query: 855 CPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
C + F GY+C+ D C S+PC +G C ++C C + YTG++C L P
Sbjct: 783 CKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAP 836
Score = 436 bits (1121), Expect = e-122
Identities = 241/664 (36%), Positives = 323/664 (48%), Gaps = 64/664 (9%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C + CL+ PC++G +C G Y C C +G+ G C +D NEC S PCQNGG
Sbjct: 717 CYSQVNECLS-NPCIHG-----NCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGG 770
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
TC + +N +RC C GF G C+ C + C + G C + C C YTG C
Sbjct: 771 TCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
Query: 385 EMDVDDCSPDPCLNGGSCVDLVG--NYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG 442
+ + CSP+PC N C + +YTCLCA ++G RC D C+S PC N G
Sbjct: 831 QTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTID----IDECISKPCMNHG 886
Query: 443 TCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCL-GANTTLCQCPLGFFGLL 498
C + Y+CECP GF G+DC E + DDC C+NGG C+ G NT C C GF G
Sbjct: 887 LCHNTQGSYMCECPPGFSGMDCEEDI-DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDK 945
Query: 499 CEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASH--SLPSPCDSDPCFNGGSC 556
C+ T M ++ C +GG C ++ SY C C + H + + C CFNGG+C
Sbjct: 946 CQ---TDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTC 1002
Query: 557 DAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCE 616
+S++C CP GF G C + CSS PC N GTC + G Y CSCP +TG++C+
Sbjct: 1003 VDGINSFSCLCPVGFTGSFC-LHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQ 1061
Query: 617 IGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPC----------FRSPC 666
+ C+ PC N GTC + +C CP G++G +C++ C C
Sbjct: 1062 T-LVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLC 1120
Query: 667 VNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDR 726
+ G C + +C C GY G C+ ++D E + T + Y C+
Sbjct: 1121 QHSGVCINAGNTHYCQCPLGYTGSYCEEQLD-----ECASNPCQHGATCSDFIGGYRCE- 1174
Query: 727 GYSLSAPSRIRVCQP--HGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE 784
C P GV E E+DEC++QPC +GG+C D V + C C G
Sbjct: 1175 ------------CVPGYQGVNCE----YEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR 1218
Query: 785 GAHCELERDECRAHP-CRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGR 843
G CE D+C P C NGG C + G Y CRC GF G CE +++ C S+PC G
Sbjct: 1219 GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGS 1278
Query: 844 --CESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYC-LASN--GSHSCTCKVGYT 898
C YLCVC +F G HCET D C PC G C +ASN C C G++
Sbjct: 1279 LDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFS 1338
Query: 899 GEDC 902
G C
Sbjct: 1339 GARC 1342
Score = 425 bits (1092), Expect = e-118
Identities = 251/801 (31%), Positives = 347/801 (43%), Gaps = 195/801 (24%)
Query: 274 ALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSF 333
A PC++G C+ G Y+C C GFTG+RC++D++ECAS PC+ G TC +G+N F
Sbjct: 650 ASNPCIHG-----ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGF 704
Query: 334 RCQCP-------------------------------------AGFGGPTCETAQSPCDTK 356
RC CP AG+ G CE ++ C +
Sbjct: 705 RCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN 764
Query: 357 ECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP 416
CQ+GG C C C+ G+ G C++++D+C+ +PCLN G+C D + YTC C P
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLP 824
Query: 417 FKGLRCETGDHPVP------------------------------------DACLSAPCHN 440
+ G C+T P D C+S PC N
Sbjct: 825 YTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMN 884
Query: 441 GGTCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCL-GANTTLCQCPLGFFG 496
G C + Y+CECP GF G+DC E + DDC C+NGG C+ G NT C C GF G
Sbjct: 885 HGLCHNTQGSYMCECPPGFSGMDCEEDI-DDCLANPCQNGGSCMDGVNTFSCLCLPGFTG 943
Query: 497 LLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASH--SLPSPCDSDPCFNGG 554
C+ ++ ++ C +GG C ++ SY C C + H + + C CFNGG
Sbjct: 944 DKCQTDMNEC---LSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGG 1000
Query: 555 SCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRH 614
+C +S++C CP GF G C + CSS PC N GTC + G Y CSCP +TG++
Sbjct: 1001 TCVDGINSFSCLCPVGFTGSFCLH-EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKN 1059
Query: 615 CEIGKPDSCASGPCHNGGTCFH------------YIGKY--------------------- 641
C+ + C+ PC N GTC + G Y
Sbjct: 1060 CQT-LVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEH 1118
Query: 642 ---------------KCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAG 686
C CP G++G +CE C +PC +G TC D + C C G
Sbjct: 1119 LCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPG 1178
Query: 687 YMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWS 746
Y G C+ EVD E ++ + GT + V + C S +R +C+ +
Sbjct: 1179 YQGVNCEYEVD-----ECQNQPCQNGGTCIDLVNHFKC----SCPPGTRGLLCEEN---- 1225
Query: 747 EPPQCLEIDECRSQP-CLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGS 805
ID+C P CL+GG C DR+ GY C C G+ G CE + +EC ++PC + GS
Sbjct: 1226 -------IDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGS 1278
Query: 806 --CRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG---AYLCVCPESFF 860
C L Y+C C + F G HCET VD C PC +GG C ++C CP F
Sbjct: 1279 LDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFS 1338
Query: 861 GYHCE----------------TVSDP-------------CFSSPCGGRGYCLASNGS--H 889
G C+ T S P C SSPC G C +
Sbjct: 1339 GARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYY 1398
Query: 890 SCTCKVGYTGEDCAKELFPPT 910
SC C ++G C PP+
Sbjct: 1399 SCQCAPPFSGSRCELYTAPPS 1419
Score = 412 bits (1058), Expect = e-114
Identities = 234/721 (32%), Positives = 307/721 (42%), Gaps = 125/721 (17%)
Query: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
PC+N G+C+D + C C GFTG C +D+++C+S PC NG C N + CQ
Sbjct: 502 PCVNNGQCVDKV----NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQ 557
Query: 337 CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPC 396
C GF G CE CD C HG QCQ S C+C GY GA C +D+C PC
Sbjct: 558 CATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC 616
Query: 397 LNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVP-------------------------- 430
LN G C+DLV Y C C G+ CE
Sbjct: 617 LNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG 676
Query: 431 -------DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRC 480
D C S PC G TC++ G+ C CPEG C +V ++C C +G
Sbjct: 677 QRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV-NECLSNPCIHGNCT 735
Query: 481 LGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTD---HNA 537
G + C C G+ G+ CE + ++ C +GG C Y C C +N
Sbjct: 736 GGLSGYKCLCDAGWVGINCEVDKNEC---LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNC 792
Query: 538 SHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKE 597
++ C S+PC N G+C YTC C + GK+C+ CS PC N CKE
Sbjct: 793 QVNIDE-CASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAP-CSPNPCENAAVCKE 850
Query: 598 AGG--EYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCE 655
+ Y C C + G+ C I D C S PC N G C + G Y C+CPPGFSG CE
Sbjct: 851 SPNFESYTCLCAPGWQGQRCTIDI-DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE 909
Query: 656 IAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTR 715
C +PC NGG+C D F C C G+ G +CQ +++ E K+ GT
Sbjct: 910 EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNG-----GTC 964
Query: 716 LGAVALYACDRGYSLSAPSRIRVCQP--HGVWSEPPQCLEIDECRSQPCLHGGSCQDRVA 773
V Y C CQ GV E I+EC C +GG+C D +
Sbjct: 965 SDYVNSYTCK-------------CQAGFDGVHCEN----NINECTESSCFNGGTCVDGIN 1007
Query: 774 GYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDAC 833
+ CLC G+ G+ C E +EC +HPC N G+C + G Y C CP G+ G +C+T V+ C
Sbjct: 1008 SFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLC 1067
Query: 834 DSSPC------------------------------------------------QHGGRCE 845
SPC QH G C
Sbjct: 1068 SRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCI 1127
Query: 846 SGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKE 905
+ G + C CP + G +CE D C S+PC C G + C C GY G +C E
Sbjct: 1128 NAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE 1187
Query: 906 L 906
+
Sbjct: 1188 V 1188
Score = 404 bits (1039), Expect = e-112
Identities = 225/653 (34%), Positives = 303/653 (46%), Gaps = 61/653 (9%)
Query: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
PCLN G+CID V G Y C+C G +G C ++ ++CAS PC +G C GIN + C
Sbjct: 615 PCLNDGRCID-LVNG---YQCNCQPGTSGVNCEINFDDCASNPCIHG-ICMDGINRYSCV 669
Query: 337 CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPC 396
C GF G C C + C+ G C C+C G +C V++C +PC
Sbjct: 670 CSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPC 729
Query: 397 LNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECP 456
++G +C + Y CLC + G+ CE + CLS PC NGGTC + GY C C
Sbjct: 730 IHG-NCTGGLSGYKCLCDAGWVGINCEVDKNE----CLSNPCQNGGTCDNLVNGYRCTCK 784
Query: 457 EGFMGLDCRERVPDDCE---CRNGGRCLG-ANTTLCQCPLGFFGLLCEFEITAMPCNMNT 512
+GF G +C+ + D+C C N G C + C C L + G C+ + PC+ N
Sbjct: 785 KGFKGYNCQVNI-DECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA--PCSPNP 841
Query: 513 QCPDGGYCMEHGG--SYLCVCHTDHNASHSLPS--PCDSDPCFNGGSCDAHDDSYTCECP 568
C + C E SY C+C C S PC N G C SY CECP
Sbjct: 842 -CENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP 900
Query: 569 RGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPC 628
GF G CE+ C + PC+NGG+C + + C C FTG C+ + C S PC
Sbjct: 901 PGFSGMDCEEDIDD-CLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM-NECLSEPC 958
Query: 629 HNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYM 688
NGGTC Y+ Y C C GF G HCE + C S C NGGTC D F C C G+
Sbjct: 959 KNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT 1018
Query: 689 GRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEP 748
G C E++ E H L GT + + Y C C P G +
Sbjct: 1019 GSFCLHEIN----ECSSHPCLN-EGTCVDGLGTYRCS-------------C-PLGYTGKN 1059
Query: 749 PQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRA----------H 798
Q L ++ C PC + G+C + A CLC +G+ GA+C++ C H
Sbjct: 1060 CQTL-VNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEH 1118
Query: 799 PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPES 858
C++ G C N + C+CP G+ G +CE ++D C S+PCQHG C G Y C C
Sbjct: 1119 LCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPG 1178
Query: 859 FFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTG-------EDCAK 904
+ G +CE D C + PC G C+ C+C G G +DCA+
Sbjct: 1179 YQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCAR 1231
Score = 362 bits (929), Expect = 1e-99
Identities = 226/686 (32%), Positives = 305/686 (44%), Gaps = 101/686 (14%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C CLA PC NGG C+D G +++C CL GFTG +C D+NEC S+PC+NGG
Sbjct: 908 CEEDIDDCLA-NPCQNGGSCMD----GVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGG 962
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
TC+ +NS+ C+C AGF G CE + C C +GG C S C+C G+TG+ C
Sbjct: 963 TCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC 1022
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
++++CS PCLN G+CVD +G Y C C + G C+T + + C +PC N GTC
Sbjct: 1023 LHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQT----LVNLCSRSPCKNKGTC 1078
Query: 445 VDADQGYVCECPEGFMGLDC------------RERVPDDCECRNGGRCLGA-NTTLCQCP 491
V C CP G+ G C R V + C++ G C+ A NT CQCP
Sbjct: 1079 VQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCP 1138
Query: 492 LGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC---HTDHNASHSLPSPCDSD 548
LG+ G CE ++ N C G C + G Y C C + N + + C +
Sbjct: 1139 LGYTGSYCEEQLDECASN---PCQHGATCSDFIGGYRCECVPGYQGVNCEYEV-DECQNQ 1194
Query: 549 PCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGP-CRNGGTCKEAGGEYHCSCP 607
PC NGG+C + + C CP G G CE+ C+ GP C NGG C + G Y C C
Sbjct: 1195 PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDD-CARGPHCLNGGQCMDRIGGYSCRCL 1253
Query: 608 YRFTGRHCEIGKPDSCASGPCHNGGT--CFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSP 665
F G CE G + C S PC + G+ C Y C C F+GRHCE C + P
Sbjct: 1254 PGFAGERCE-GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMP 1312
Query: 666 CVNGGTC---EDRDTDFFCHCQAGYMGRRCQA---EVDCGPPEEVKHATLRFNGTRLGAV 719
C+NGGTC + F C C G+ G RCQ+ +V C E+ H +G R
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTA---SGPRCFCP 1369
Query: 720 ALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSC--QDRVAGYLC 777
+ C+ G C S PC HGGSC Q + Y C
Sbjct: 1370 SPRDCESG-----------------------------CASSPCQHGGSCHPQRQPPYYSC 1400
Query: 778 LCSTGYEGAHCEL-------ERDECRAHPCRN---GGSCRNLPGAYVCRCPAGFVGVHCE 827
C+ + G+ CEL C + C + G C ++ C+ G + E
Sbjct: 1401 QCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTME 1460
Query: 828 TEVDACDSS-PCQH--GGRCESGGGAYLCVCPESFF-GYHCETVSDPC-FSSPCGGR--- 879
C S PC +C+ LC E F + C+ S C + C
Sbjct: 1461 NPWANCSSPLPCWDYINNQCDE-----LCNTVECLFDNFECQGNSKTCKYDKYCADHFKD 1515
Query: 880 GYCLASNGSHSCTCKVGYTGEDCAKE 905
+C S C G+ G DCA +
Sbjct: 1516 NHCDQGCNSEEC----GWDGLDCAAD 1537
Score = 339 bits (869), Expect = 1e-92
Identities = 200/588 (34%), Positives = 265/588 (45%), Gaps = 53/588 (9%)
Query: 337 CPAGFGGPTCETAQSPCDTKECQHGGQCQV-ENGSAVCVCQAGYTGAACEMDVDDCSPDP 395
C A C PC + G C NG+ C C G+ G C+ D C +
Sbjct: 19 CAAPAHALQCRDGYEPCVNE-----GMCVTYHNGTGYCKCPEGFLGEYCQHR-DPCEKNR 72
Query: 396 CLNGGSCVD--LVGNYTCLCAEPFKGLRCE-TGDHPVPDACLSAPCHNGGTC-VDADQGY 451
C NGG+CV ++G TC CA F G C+ + HP +S PC NGGTC + + Y
Sbjct: 73 CQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP---CFVSRPCLNGGTCHMLSRDTY 129
Query: 452 VCECPEGFMGLDCRERVPDDC---ECRNGGRCLG-ANTTLCQCPLGFFGLLCEFEITAMP 507
C C GF G +C+ D C C NG C AN C+C GF G CE ++
Sbjct: 130 ECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE-- 185
Query: 508 CNMNTQCPDGGYCMEHGGSYLCVCHTDHNASH--SLPSPCDSDPCFNGGSC-DAHDDSYT 564
C++ C GG C+ GSY C C + SL PC PC NGG+C D ++
Sbjct: 186 CDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFE 245
Query: 565 CECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCA 624
C C GF G CE+ C + C+NGG C + Y+C CP ++TG+ C D C
Sbjct: 246 CNCLPGFEGSTCERNIDD-CPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCT-EDVDECL 303
Query: 625 SGP--CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCH 682
P C NGGTC + G Y C C G+SG C C + C G TC DR F C
Sbjct: 304 LQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCM 363
Query: 683 CQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPH 742
C G G C + C K A N L + C +GY
Sbjct: 364 CPEGKAGLLCHLDDACISNPCHKGALCDTNP--LNGQYICTCPQGY-------------- 407
Query: 743 GVWSEPPQCLE-IDEC---RSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAH 798
+ C E +DEC S PC H G C + + C C GY G CE++ +EC +
Sbjct: 408 ----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSD 463
Query: 799 PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPES 858
PC+N +C + G + C C GF GVHCE E++ C S+PC + G+C + C+CP
Sbjct: 464 PCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPG 523
Query: 859 FFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
F G C+ D C S+PC C+ + C C G+TG C + +
Sbjct: 524 FTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI 571
Score = 53.5 bits (127), Expect = 1e-06
Identities = 32/96 (33%), Positives = 46/96 (47%), Gaps = 8/96 (8%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPCTRLFSETKAFPVWEGG 1369
C NPCQNGGTC + + C C GFKG C++ + S PC ++ F G
Sbjct: 761 CLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPC---LNQGTCFDDISGY 817
Query: 1370 VCHHVYKRVYRVHQDI---CFKESCESTSL-KKTPN 1401
CH V + Q + C CE+ ++ K++PN
Sbjct: 818 TCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPN 853
Score = 50.8 bits (120), Expect = 9e-06
Identities = 21/45 (46%), Positives = 29/45 (64%), Gaps = 1/45 (2%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
+C NPCQNGG+C+ G + SC C PGF G +C+ + +S PC
Sbjct: 914 DCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPC 958
Score = 47.4 bits (111), Expect = 1e-04
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 12/87 (13%)
Query: 1311 CSENPCQNGGTCVPGA--DAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEG 1368
C +N CQNGGTCV A +C C GF G C+ + S PC + P G
Sbjct: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYS---TSHPC------FVSRPCLNG 118
Query: 1369 GVCHHVYKRVYRVHQDICFK-ESCEST 1394
G CH + + Y + F + C+ T
Sbjct: 119 GTCHMLSRDTYECTCQVGFTGKECQWT 145
Score = 47.4 bits (111), Expect = 1e-04
Identities = 26/66 (39%), Positives = 32/66 (48%), Gaps = 9/66 (13%)
Query: 1311 CSENPCQNGGTCVPGADA--HSCDCGPGFKGRRCELACIKVSRP---CTRLFSETKAFPV 1365
C+ +PCQ+GG+C P +SC C P F G RCEL S P C + KA
Sbjct: 1378 CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKA--- 1434
Query: 1366 WEGGVC 1371
GVC
Sbjct: 1435 -RDGVC 1439
Score = 47.0 bits (110), Expect = 1e-04
Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 21/83 (25%)
Query: 1311 CSENPCQNGGTCVPGA---DAHSCDCGPGFKGRRCELACIKV----SRPCTRLFSETKAF 1363
C + PC NGGTC + D C C PGF G RC+ +C +V C S + F
Sbjct: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCF 1367
Query: 1364 --------------PVWEGGVCH 1372
P GG CH
Sbjct: 1368 CPSPRDCESGCASSPCQHGGSCH 1390
Score = 46.6 bits (109), Expect = 2e-04
Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Query: 1296 LPEHGSKDIGNVPGNCSENPCQNGGTCV--PGADAHSCDCGPGFKGRRCELACIK-VSRP 1352
LP G K+ V CS NPC+N C P ++++C C PG++G+RC + + +S+P
Sbjct: 823 LPYTG-KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP 881
Query: 1353 C 1353
C
Sbjct: 882 C 882
Score = 44.7 bits (104), Expect = 6e-04
Identities = 20/44 (45%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
C +PCQN TC+ +C C PGFKG CEL + S PC
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPC 503
Score = 44.7 bits (104), Expect = 6e-04
Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPCTR 1355
+C+ NPC +G C+ G + +SC C PGF G+RC + + S PC +
Sbjct: 648 DCASNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRK 693
Score = 44.7 bits (104), Expect = 6e-04
Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSR-PC 1353
CS +PC N GTCV G + C C G+ G+ C+ SR PC
Sbjct: 1029 CSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPC 1072
Score = 44.3 bits (103), Expect = 8e-04
Identities = 16/33 (48%), Positives = 19/33 (57%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C PCQNGGTC+ + C C PG +G CE
Sbjct: 1191 CQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCE 1223
Score = 43.9 bits (102), Expect = 0.001
Identities = 15/33 (45%), Positives = 21/33 (63%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C+ NPCQ+G TC + C+C PG++G CE
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCECVPGYQGVNCE 1185
Score = 42.4 bits (98), Expect = 0.003
Identities = 16/33 (48%), Positives = 20/33 (60%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C +PC NG TC A+ SC C GF G++CE
Sbjct: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE 180
Score = 42.4 bits (98), Expect = 0.003
Identities = 17/32 (53%), Positives = 21/32 (65%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
C+E+ C NGGTCV G ++ SC C GF G C
Sbjct: 991 CTESSCFNGGTCVDGINSFSCLCPVGFTGSFC 1022
Score = 42.0 bits (97), Expect = 0.004
Identities = 15/33 (45%), Positives = 20/33 (60%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C PC+NGGTC ++++C C GF G CE
Sbjct: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCE 985
Score = 42.0 bits (97), Expect = 0.004
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 1310 NCSENP-CQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPCT 1354
+C+ P C NGG C+ +SC C PGF G RCE + +S PC+
Sbjct: 1228 DCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCS 1274
Score = 41.6 bits (96), Expect = 0.005
Identities = 17/34 (50%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 1311 CSENPCQNGGTCVPGAD-AHSCDCGPGFKGRRCE 1343
C+ +PC NGGTC D C+C PGF+G CE
Sbjct: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE 258
Score = 40.8 bits (94), Expect = 0.009
Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 1315 PCQNGGTC-VPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
PC NGGTC + D + C C GF G+ C+ +S PC
Sbjct: 114 PCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPC 153
Score = 40.8 bits (94), Expect = 0.009
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
+C + CQNGG CV G + ++C C P + G+ C
Sbjct: 263 DCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
Score = 40.4 bits (93), Expect = 0.012
Identities = 15/34 (44%), Positives = 18/34 (52%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C NPC N G CV + C C PGF G C++
Sbjct: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Score = 40.4 bits (93), Expect = 0.012
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
+CS PC NG C+ + + C C GF G CE
Sbjct: 535 DCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE 568
Score = 38.9 bits (89), Expect = 0.035
Identities = 13/34 (38%), Positives = 19/34 (55%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C +PC N G C+ + + C+C PG G CE+
Sbjct: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEI 644
Score = 38.5 bits (88), Expect = 0.046
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C PC N G C ++ C+C PGF G CE
Sbjct: 877 CISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE 909
Score = 38.1 bits (87), Expect = 0.060
Identities = 14/33 (42%), Positives = 20/33 (60%)
Query: 1312 SENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
+ NPC++ G CV A C+C G+ G RCE+
Sbjct: 423 NSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEM 455
Score = 38.1 bits (87), Expect = 0.060
Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
NC +PC +G C G D+++C C PG+ G C
Sbjct: 573 NCDPDPCHHG-QCQDGIDSYTCICNPGYMGAIC 604
Score = 37.7 bits (86), Expect = 0.079
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 15/76 (19%)
Query: 1306 NVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVS-RPCTR--------- 1355
++PG+C Q+GGTC+ ++ C C GF G+ C+ + + PC
Sbjct: 187 DIPGHC-----QHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGD 241
Query: 1356 LFSETKAFPVWEGGVC 1371
E P +EG C
Sbjct: 242 FTFECNCLPGFEGSTC 257
Score = 36.6 bits (83), Expect = 0.18
Identities = 14/34 (41%), Positives = 19/34 (55%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
CS +PC+N GTCV C C G+ G C++
Sbjct: 1067 CSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDV 1100
Score = 35.4 bits (80), Expect = 0.39
Identities = 25/94 (26%), Positives = 34/94 (36%), Gaps = 16/94 (17%)
Query: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRCE--------LACIKVSRPCTRLFSETKAFPV 1365
N CQNGGTC + C C G+ G C +C S R+ S + P
Sbjct: 307 NACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPE 366
Query: 1366 WEGGVCHHVYKRVYRVHQDICFKESCESTSLKKT 1399
+ G+ H+ D C C +L T
Sbjct: 367 GKAGLLCHL--------DDACISNPCHKGALCDT 392
Score = 35.4 bits (80), Expect = 0.39
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 1313 ENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
E+ CQ+ G C+ + H C C G+ G CE + S PC
Sbjct: 1117 EHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPC 1158
Score = 34.3 bits (77), Expect = 0.87
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 1310 NCSEN-------PCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
+CSEN C G TC+ + SC C G G C L +S PC
Sbjct: 334 DCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPC 384
Score = 34.3 bits (77), Expect = 0.87
Identities = 11/26 (42%), Positives = 15/26 (57%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPG 1336
C+ NPC+ G TC+ G + C C G
Sbjct: 686 CASNPCRKGATCINGVNGFRCICPEG 711
Score = 32.7 bits (73), Expect = 2.5
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 6/46 (13%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL---ACIKVSRPC 1353
C NPC +G C G + C C G+ G CE+ C+ S PC
Sbjct: 724 CLSNPCIHGN-CTGGLSGYKCLCDAGWVGINCEVDKNECL--SNPC 766
Score = 31.6 bits (70), Expect = 5.6
Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 6/69 (8%)
Query: 1291 SLALQLPEHGSKDIGNVPGNCSENPCQNGGTC--VPGADAHSCDCGPGFKGRRC----EL 1344
S + PE + + ++ C NPC G C P + C C G+KG C +
Sbjct: 359 SFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDE 418
Query: 1345 ACIKVSRPC 1353
+ S PC
Sbjct: 419 CAMANSNPC 427
Score = 31.6 bits (70), Expect = 5.6
Identities = 13/35 (37%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 1311 CSENPCQNGGT--CVPGADAHSCDCGPGFKGRRCE 1343
C NPC + G+ C+ + + C C F GR CE
Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 443 bits (1139), Expect = e-124
Identities = 240/655 (36%), Positives = 318/655 (48%), Gaps = 64/655 (9%)
Query: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNEC-ASQPCQNGGTCTHGI 330
CL+ PC +G +C V + + CSC G+ GR C DV+EC +PC++GGTC +
Sbjct: 123 CLS-SPCAHGARC---SVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTP 178
Query: 331 NSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAV--CVCQAGYTGAACEMDV 388
SFRCQCPAG+ GP CE PC C++GG C+ ++G C C G+ G CE++V
Sbjct: 179 GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCR-QSGDLTYDCACLPGFEGQNCEVNV 237
Query: 389 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAP--CHNGGTCVD 446
DDC CLNGG+CVD V Y C C + G C T D D C P CHNGGTC +
Sbjct: 238 DDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC-TED---VDECQLQPNACHNGGTCFN 293
Query: 447 ADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGANTTL-CQCPLGFFGLLCEFE 502
G+ C C G+ G C + + DDC C +G C + C CP+G GLLC +
Sbjct: 294 TLGGHSCVCVNGWTGESCSQNI-DDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD 352
Query: 503 --ITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSD---------PCF 551
+ PC+ + C G +C C CD D PC
Sbjct: 353 DACVSNPCHEDAICDTNPV----NGRAICTCPPGFTG-----GACDQDVDECSIGANPCE 403
Query: 552 NGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFT 611
+ G C S+ C+C RG+ G CE + C SGPCRN TC + G++ C C FT
Sbjct: 404 HLGRCVNTQGSFLCQCGRGYTGPRCE-TDVNECLSGPCRNQATCLDRIGQFTCICMAGFT 462
Query: 612 GRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGT 671
G +CE+ D C S PC NGG C + + C CP GFSG C++ C +PC NG
Sbjct: 463 GTYCEV-DIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAK 521
Query: 672 CEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLS 731
C D+ + C C G+ G C VD P+ H G + +A ++C
Sbjct: 522 CVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHH------GRCVDGIASFSC------- 568
Query: 732 APSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE 791
C P + ++DECRSQPC HGG C D V YLC C +G G +CE+
Sbjct: 569 ------ACAPGYTGTRCES--QVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVN 620
Query: 792 RDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAY 851
D+C ++PC G CR+ Y C C GF G C E++ C SSPC GG C G +
Sbjct: 621 IDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGF 679
Query: 852 LCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
C+CP C S PC PC G C + G C C+ G++G C++ L
Sbjct: 680 RCLCPPGSLPPLCLPPSHPCAHEPC-SHGICYDAPGGFRCVCEPGWSGPRCSQSL 733
Score = 438 bits (1127), Expect = e-122
Identities = 234/653 (35%), Positives = 316/653 (48%), Gaps = 54/653 (8%)
Query: 263 GGCGHTTSVC-LALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQ 321
G C C + PC + G+C++ S+ C C G+TG RC DVNEC S PC+
Sbjct: 386 GACDQDVDECSIGANPCEHLGRCVNT----QGSFLCQCGRGYTGPRCETDVNECLSGPCR 441
Query: 322 NGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTG 381
N TC I F C C AGF G CE C + C +GG C+ C C +G++G
Sbjct: 442 NQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSG 501
Query: 382 AACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNG 441
+ C++DVD+C+ PC NG CVD Y C CAE F+G C+ D C PCH+
Sbjct: 502 STCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRN----VDDCSPDPCHH- 556
Query: 442 GTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLG-ANTTLCQCPLGFFGL 497
G CVD + C C G+ G C +V D+C CR+GG+CL + LC+CP G G+
Sbjct: 557 GRCVDGIASFSCACAPGYTGTRCESQV-DECRSQPCRHGGKCLDLVDKYLCRCPSGTTGV 615
Query: 498 LCEFEI---TAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNA--SHSLPSPCDSDPCFN 552
CE I + PC G C + Y CVC + + C S PC
Sbjct: 616 NCEVNIDDCASNPCTF-------GVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGE 668
Query: 553 GGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTG 612
GGSC ++ + C CP G C H C+ PC + G C +A G + C C ++G
Sbjct: 669 GGSCVDGENGFRCLCPPGSLPPLC-LPPSHPCAHEPCSH-GICYDAPGGFRCVCEPGWSG 726
Query: 613 RHCEIG-KPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGT 671
C D+C S PC GGTC + C CPPG GR CE+ SPC +PC +GG
Sbjct: 727 PRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELL-SPCTPNPCEHGGR 785
Query: 672 CEDRDTDF-FCHCQAGYMGRRCQAEVD-CGPPEEVKHATLRFNGTRLGAVALYACDRGYS 729
CE C C G+ G RCQ +VD C P A +G ++C
Sbjct: 786 CESAPGQLPVCSCPQGWQGPRCQQDVDECAGP-----APCGPHGICTNLAGSFSC----- 835
Query: 730 LSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE 789
C HG ++ P +I++C PCL+GGSCQD V + C C G+ G C
Sbjct: 836 --------TC--HGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCA 885
Query: 790 LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 849
+ DEC ++PC G+C + ++ C CP G+ G HCE ++ C S C +GG C G
Sbjct: 886 RDVDECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVN 944
Query: 850 AYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
++ C+C + G HC+ +DPC S PC G C A++ CTC +TG C
Sbjct: 945 SFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQC 997
Score = 429 bits (1102), Expect = e-119
Identities = 240/715 (33%), Positives = 311/715 (43%), Gaps = 102/715 (14%)
Query: 274 ALRPCLNGGKCIDD---------------------------------CVTGNPSYTCSCL 300
A PC NG KC+D CV G S++C+C
Sbjct: 512 ASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACA 571
Query: 301 SGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQH 360
G+TG RC V+EC SQPC++GG C ++ + C+CP+G G CE C + C
Sbjct: 572 PGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTF 631
Query: 361 GGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGL 420
G C+ CVCQ G+TG C +++++C+ PC GGSCVD + CLC
Sbjct: 632 G-VCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPP 690
Query: 421 RCETGDHPVP-----------------------------------DACLSAPCHNGGTCV 445
C HP DAC S PC GGTC
Sbjct: 691 LCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCS 750
Query: 446 DADQGYVCECPEGFMGLDCRERVP-DDCECRNGGRCLGANTTL--CQCPLGFFGLLCEFE 502
G+ C CP G G C P C +GGRC A L C CP G+ G C+ +
Sbjct: 751 SDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQD 810
Query: 503 ITAMPCNMNTQCPDGGYCMEHGGSYLCVCH---TDHNASHSLPSPCDSDPCFNGGSCDAH 559
+ C C G C GS+ C CH T + + + CD +PC NGGSC
Sbjct: 811 VDE--CAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDI-NDCDPNPCLNGGSCQDG 867
Query: 560 DDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGK 619
S++C C GF G C + C S PC GTC + + C+CP + G HCE
Sbjct: 868 VGSFSCSCLPGFAGPRCARDVDE-CLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDL 925
Query: 620 PDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 679
PD C+ C NGGTC + + C C PG++G HC+ PC PC++GG C F
Sbjct: 926 PD-CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGF 984
Query: 680 FCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYA-CDRGYSLSAPSRIRV 738
C C + G +CQ VD + + NG R Y C G+S R+
Sbjct: 985 RCTCLESFTGPQCQTLVDWCSRQPCQ------NGGRCVQTGAYCLCPPGWSG------RL 1032
Query: 739 CQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAH 798
C + +I Q C GG C D + + C+C G G+HCE E D C A
Sbjct: 1033 CDIRSLPCREAAA-QIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQ 1091
Query: 799 PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPES 858
PC++GG+CR G Y+C C G+ G +CE +VD C S PCQHGG C YLC CP
Sbjct: 1092 PCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPG 1151
Query: 859 FFGYHCETVSDPCFSSP-------CGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
G CE D C P C G C+ G CTC GYTG C ++
Sbjct: 1152 TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADI 1206
Score = 422 bits (1084), Expect = e-117
Identities = 236/699 (33%), Positives = 323/699 (46%), Gaps = 56/699 (8%)
Query: 243 TNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSG 302
T + PG +FR G +V A PC NGG C +G+ +Y C+CL G
Sbjct: 173 TCLNTPG--SFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQ---SGDLTYDCACLPG 227
Query: 303 FTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTK--ECQH 360
F G+ C ++V++C C NGGTC G+N++ CQCP + G C C + C +
Sbjct: 228 FEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHN 287
Query: 361 GGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGL 420
GG C G CVC G+TG +C ++DDC+ C +G +C D V ++ C C GL
Sbjct: 288 GGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGL 347
Query: 421 RCETGDHPVPDACLSAPCHNGGTC--VDADQGYVCECPEGFMGLDCRERVPDDCE----- 473
C + DAC+S PCH C + +C CP GF G C + V D+C
Sbjct: 348 LCH-----LDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDV-DECSIGANP 401
Query: 474 CRNGGRCLGA-NTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCH 532
C + GRC+ + LCQC G+ G CE ++ ++ C + C++ G + C+C
Sbjct: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNEC---LSGPCRNQATCLDRIGQFTCICM 458
Query: 533 TDHNASHSLP--SPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCR 590
++ C S PC NGG C + ++C CP GF G C+ C+S PCR
Sbjct: 459 AGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDE-CASTPCR 517
Query: 591 NGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFS 650
NG C + Y C C F G C+ D C+ PCH+ G C I + C C PG++
Sbjct: 518 NGAKCVDQPDGYECRCAEGFEGTLCD-RNVDDCSPDPCHH-GRCVDGIASFSCACAPGYT 575
Query: 651 GRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLR 710
G CE C PC +GG C D + C C +G G C+ +D R
Sbjct: 576 GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR 635
Query: 711 -------------FNG----TRLGAVALYACDRGYS-LSAPSRIRVCQPHGVWSEPPQCL 752
F G + A C G S + + R P G S PP CL
Sbjct: 636 DGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPG--SLPPLCL 693
Query: 753 EIDE-CRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHC--ELERDECRAHPCRNGGSCRNL 809
C +PC H G C D G+ C+C G+ G C L RD C + PCR GG+C +
Sbjct: 694 PPSHPCAHEPCSH-GICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSD 752
Query: 810 PGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAY-LCVCPESFFGYHCETVS 868
+ C CP G G CE + C +PC+HGGRCES G +C CP+ + G C+
Sbjct: 753 GMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDV 811
Query: 869 DPCFS-SPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
D C +PCG G C GS SCTC GYTG C +++
Sbjct: 812 DECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDI 850
Score = 420 bits (1079), Expect = e-117
Identities = 248/699 (35%), Positives = 318/699 (45%), Gaps = 109/699 (15%)
Query: 262 VGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPS--YTCSCLSGFTGRRCHLDVNECASQP 319
+ G G CL PC NGG+C T PS C C G+ G RC L+ + C S P
Sbjct: 33 LAGPGAAAPPCLDGSPCANGGRC-----TQLPSREAACLCPPGWVGERCQLE-DPCHSGP 86
Query: 320 CQNGGTC----THGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQV-ENGSAVCV 374
C G C G F C+CP GF GP C + PC + C HG +C V +G +C
Sbjct: 87 CAGRGVCQSSVVAGTARFSCRCPRGFRGPDC-SLPDPCLSSPCAHGARCSVGPDGRFLCS 145
Query: 375 CQAGYTGAACEMDVDDCS-PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDAC 433
C GY G +C DVD+C +PC +GG+C++ G++ C C + G CE P C
Sbjct: 146 CPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP----C 201
Query: 434 LSAPCHNGGTC-VDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCL-GANTTLC 488
+PC NGGTC D Y C C GF G +C V DDC C NGG C+ G NT C
Sbjct: 202 APSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNV-DDCPGHRCLNGGTCVDGVNTYNC 260
Query: 489 QCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC---HTDHNASHSLPSPC 545
QCP + G C ++ N C +GG C G + CVC T + S ++ C
Sbjct: 261 QCPPEWTGQFCTEDVDECQLQPNA-CHNGGTCFNTLGGHSCVCVNGWTGESCSQNI-DDC 318
Query: 546 DSDPCFNGGSC-----------------------------DAHDDSY----------TCE 566
+ CF+G +C H+D+ C
Sbjct: 319 ATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICT 378
Query: 567 CPRGFHGKHCEKARPHLCSSG--PCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCA 624
CP GF G C++ CS G PC + G C G + C C +TG CE + C
Sbjct: 379 CPPGFTGGACDQDVDE-CSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCET-DVNECL 436
Query: 625 SGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ 684
SGPC N TC IG++ C C GF+G +CE+ C SPCVNGG C+DR F C C
Sbjct: 437 SGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCP 496
Query: 685 AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGV 744
+G+ G CQ +VD E R NG + V QP G
Sbjct: 497 SGFSGSTCQLDVD-----ECASTPCR-NGAKC---------------------VDQPDGY 529
Query: 745 WSEPPQCLE-------IDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRA 797
+ E +D+C PC H G C D +A + C C+ GY G CE + DECR+
Sbjct: 530 ECRCAEGFEGTLCDRNVDDCSPDPC-HHGRCVDGIASFSCACAPGYTGTRCESQVDECRS 588
Query: 798 HPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPE 857
PCR+GG C +L Y+CRCP+G GV+CE +D C S+PC G C G Y CVC
Sbjct: 589 QPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTF-GVCRDGINRYDCVCQP 647
Query: 858 SFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVG 896
F G C + C SSPCG G C+ C C G
Sbjct: 648 GFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPG 686
Score = 409 bits (1052), Expect = e-114
Identities = 228/654 (34%), Positives = 303/654 (46%), Gaps = 50/654 (7%)
Query: 267 HTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECA--SQPCQNGG 324
H C++ PC C + V G C+C GFTG C DV+EC+ + PC++ G
Sbjct: 350 HLDDACVS-NPCHEDAICDTNPVNGRA--ICTCPPGFTGGACDQDVDECSIGANPCEHLG 406
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
C + SF CQC G+ GP CET + C + C++ C G C+C AG+TG C
Sbjct: 407 RCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYC 466
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
E+D+D+C PC+NGG C D V ++C C F G C+ D C S PC NG C
Sbjct: 467 EVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLD----VDECASTPCRNGAKC 522
Query: 445 VDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCL-GANTTLCQCPLGFFGLLCE 500
VD GY C C EGF G C V DDC C +G RC+ G + C C G+ G CE
Sbjct: 523 VDQPDGYECRCAEGFEGTLCDRNV-DDCSPDPCHHG-RCVDGIASFSCACAPGYTGTRCE 580
Query: 501 FEITAMPCNMNTQCPDGGYCMEHGGSYLCVCH---TDHNASHSLPSPCDSDPCFNGGSCD 557
++ + C GG C++ YLC C T N ++ C S+PC G C
Sbjct: 581 SQVDEC---RSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDD-CASNPC-TFGVCR 635
Query: 558 AHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEI 617
+ Y C C GF G C + C+S PC GG+C + + C CP C +
Sbjct: 636 DGINRYDCVCQPGFTGPLCN-VEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLC-L 693
Query: 618 GKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCE--IAPSPCFRSPCVNGGTCEDR 675
CA PC +G C+ G ++C C PG+SG C +A C PC GGTC
Sbjct: 694 PPSHPCAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSD 752
Query: 676 DTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSR 735
F C C G GR+C+ C P +H G SAP +
Sbjct: 753 GMGFHCTCPPGVQGRQCELLSPC-TPNPCEHG-------------------GRCESAPGQ 792
Query: 736 IRVCQPHGVWSEPPQCLEIDECRSQ-PCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDE 794
+ VC W P ++DEC PC G C + + C C GY G C+ + ++
Sbjct: 793 LPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDIND 852
Query: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCV 854
C +PC NGGSC++ G++ C C GF G C +VD C S+PC G C ++ C
Sbjct: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCT 911
Query: 855 CPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
CP + G+HCE C S C G C+ S SC C+ GYTG C E P
Sbjct: 912 CPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP 965
Score = 367 bits (941), Expect = e-101
Identities = 228/701 (32%), Positives = 302/701 (43%), Gaps = 84/701 (11%)
Query: 276 RPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFR- 334
+PC GG C D + + C+C G GR+C L ++ C PC++GG C
Sbjct: 741 QPCRAGGTCSSDGM----GFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPV 795
Query: 335 CQCPAGFGGPTCETAQSPC-DTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSP 393
C CP G+ GP C+ C C G C GS C C GYTG +C+ D++DC P
Sbjct: 796 CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP 855
Query: 394 DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVC 453
+PCLNGGSC D VG+++C C F G RC D CLS PC GTC D + C
Sbjct: 856 NPCLNGGSCQDGVGSFSCSCLPGFAGPRCARD----VDECLSNPC-GPGTCTDHVASFTC 910
Query: 454 ECPEGFMGLDCRERVPD--DCECRNGGRCL-GANTTLCQCPLGFFGLLCEFEITAMPCNM 510
CP G+ G C + +PD C NGG C+ G N+ C C G+ G C+ E A PC +
Sbjct: 911 TCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE--ADPC-L 967
Query: 511 NTQCPDGGYCMEHGGSYLCVCHTDHNASH--SLPSPCDSDPCFNGGSCDAHDDSYTCECP 568
+ C GG C + C C +L C PC NGG C +Y C CP
Sbjct: 968 SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC-VQTGAY-CLCP 1025
Query: 569 RGFHGKHCEKARPHLCSSGP----------CRNGGTCKEAGGEYHCSCPYRFTGRHCEIG 618
G+ G+ C+ R C C+ GG C + ++C CP TG HCE
Sbjct: 1026 PGWSGRLCD-IRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE-Q 1083
Query: 619 KPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTD 678
+ D C + PC +GGTC Y+G Y C+C PG++G +CE C PC +GG+C D
Sbjct: 1084 EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVAR 1143
Query: 679 FFCHCQAGYMGRRCQA-EVDCGP-PEEVKHATLRFNGTRLGAVALY--ACDRGYS----- 729
+ C C G +G C+ E DCGP P NGT + V + C GY+
Sbjct: 1144 YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203
Query: 730 -------------------LSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQD 770
L P C H +S P + C SQPC HGG C+
Sbjct: 1204 ADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRP 1263
Query: 771 RVAG-----YLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVH 825
+ C C+ + G CE CR C G C+ P C CP G G
Sbjct: 1264 SPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPS 1323
Query: 826 CET--------EVDACDSSPCQHGGRCESGGGA--YLCVCPESFFGYHCE--TVSDPCFS 873
C + +C ++PC HGG C A + C C + + G CE +
Sbjct: 1324 CRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSE 1383
Query: 874 SPCGGRGYCLASNGSHSCTCK-----VGYTGEDCAKELFPP 909
P R C A G C + G+ G DC+ + P
Sbjct: 1384 EPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDP 1424
Score = 345 bits (885), Expect = 2e-94
Identities = 228/714 (31%), Positives = 298/714 (41%), Gaps = 111/714 (15%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C C PC G C + + G S++C+C G+TG C D+N+C PC NGG
Sbjct: 807 CQQDVDECAGPAPCGPHGICTN--LAG--SFSCTCHGGYTGPSCDQDINDCDPNPCLNGG 862
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
+C G+ SF C C GF GP C C + C G C S C C GY G C
Sbjct: 863 SCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYGGFHC 921
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
E D+ DCSP C NGG+CVD V +++CLC + G C+ H D CLS PC +GG C
Sbjct: 922 EQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ---HEA-DPCLSRPCLHGGVC 977
Query: 445 VDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGANTTLCQCPLGFFGLLCEF 501
A G+ C C E F G C+ V D C C+NGGRC+ C CP G+ G LC+
Sbjct: 978 SAAHPGFRCTCLESFTGPQCQTLV-DWCSRQPCQNGGRCVQTGA-YCLCPPGWSGRLCD- 1034
Query: 502 EITAMPCN---------MNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS--PCDSDPC 550
I ++PC + C GG C++ S+ CVC SH PC + PC
Sbjct: 1035 -IRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPC 1093
Query: 551 FNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRF 610
+GG+C + Y CEC G++G +CE C+S PC++GG+C + Y CSCP
Sbjct: 1094 QHGGTCRGYMGGYMCECLPGYNGDNCEDDVDE-CASQPCQHGGSCIDLVARYLCSCPPGT 1152
Query: 611 TGRHCEIGKPDSCASGP-------CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFR 663
G CEI + D C GP C + GTC +G ++C CPPG++G CE + C
Sbjct: 1153 LGVLCEINE-DDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRS 1211
Query: 664 SPCVNGGT---CEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA 720
C T +D F C C AG+ G RCQ + + +H G
Sbjct: 1212 GACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGL 1271
Query: 721 LYACDRGYSLSAPSRIRV--------------CQ--PHGVWSEPPQCLEIDECRS----- 759
+ C P RV CQ P G P L CRS
Sbjct: 1272 TFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSP 1331
Query: 760 ----------QPCLHGGSCQDRVAG--YLCLCSTGYEGAHCEL--------ERDECRAHP 799
PCLHGGSC+ + C C+ G+ G CE E C
Sbjct: 1332 PGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAA 1391
Query: 800 CR-------------------NGGSCRNLPGAYVCRCPAG-----FVGVHCETEVD--AC 833
C+ +GG C G +C A F C+ AC
Sbjct: 1392 CQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPAC 1451
Query: 834 --DSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLAS 885
D+ C GGR + Y C + F C+ C + CG G AS
Sbjct: 1452 LYDNFDCHAGGRERTCNPVYEKYCADHFADGRCD---QGCNTEECGWDGLDCAS 1502
Score = 327 bits (838), Expect = 5e-89
Identities = 178/529 (33%), Positives = 241/529 (45%), Gaps = 47/529 (8%)
Query: 395 PCLNGGSCVDLVGNYT-CLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC----VDADQ 449
PC NGG C L CLC + G RC+ + D C S PC G C V
Sbjct: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQ-----LEDPCHSGPCAGRGVCQSSVVAGTA 102
Query: 450 GYVCECPEGFMGLDCRERVPDDC---ECRNGGRC-LGANTT-LCQCPLGFFGLLCEFEIT 504
+ C CP GF G DC +PD C C +G RC +G + LC CP G+ G C ++
Sbjct: 103 RFSCRCPRGFRGPDCS--LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVD 160
Query: 505 AMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNAS--HSLPSPCDSDPCFNGGSCDAHDD- 561
C + C GG C+ GS+ C C + + PC PC NGG+C D
Sbjct: 161 E--CRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDL 218
Query: 562 SYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPD 621
+Y C C GF G++CE C C NGGTC + Y+C CP +TG+ C D
Sbjct: 219 TYDCACLPGFEGQNCE-VNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCT-EDVD 276
Query: 622 SCASGP--CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 679
C P CHNGGTCF+ +G + C C G++G C C + C +G TC DR F
Sbjct: 277 ECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASF 336
Query: 680 FCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVC 739
+C C G G C + C H + + A+ C G++ A +
Sbjct: 337 YCACPMGKTGLLCHLDDAC--VSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQ---- 390
Query: 740 QPHGVWSEPPQCLEIDECR--SQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRA 797
++DEC + PC H G C + +LC C GY G CE + +EC +
Sbjct: 391 -------------DVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLS 437
Query: 798 HPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPE 857
PCRN +C + G + C C AGF G +CE ++D C SSPC +GG C+ + C CP
Sbjct: 438 GPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS 497
Query: 858 SFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
F G C+ D C S+PC C+ + C C G+ G C + +
Sbjct: 498 GFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNV 546
Score = 117 bits (294), Expect = 6e-26
Identities = 67/173 (38%), Positives = 81/173 (46%), Gaps = 14/173 (8%)
Query: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYL-CLCSTGYEGAHCELERDECRAHPCR 801
G + P CL+ PC +GG C + CLC G+ G C+LE D C + PC
Sbjct: 35 GPGAAAPPCLD-----GSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCA 88
Query: 802 NGGSCRNLPGA----YVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESG-GGAYLCVCP 856
G C++ A + CRCP GF G C D C SSPC HG RC G G +LC CP
Sbjct: 89 GRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCP 147
Query: 857 ESFFGYHCETVSDPC-FSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
+ G C + D C PC G CL + GS C C GYTG C P
Sbjct: 148 PGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP 200
Score = 48.9 bits (115), Expect = 3e-05
Identities = 26/63 (41%), Positives = 33/63 (52%), Gaps = 13/63 (20%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE-LACIKVSRPCTRLFSETKAFPVWEG 1368
+CS + C NGGTCV G ++ SC C PG+ G C+ A +SRPC G
Sbjct: 927 DCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCL------------HG 974
Query: 1369 GVC 1371
GVC
Sbjct: 975 GVC 977
Score = 48.5 bits (114), Expect = 4e-05
Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
+C NPC NGG+C G + SC C PGF G RC + +S PC
Sbjct: 852 DCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC 896
Score = 48.5 bits (114), Expect = 4e-05
Identities = 58/206 (28%), Positives = 78/206 (37%), Gaps = 35/206 (16%)
Query: 266 GHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGT 325
G + + C A PCL+GG C + P + C+C G+TG RC A+
Sbjct: 1333 GASNASCAAA-PCLHGGSCRPAPLA--PFFRCACAQGWTGPRCEA---PAAAPEVSEEPR 1386
Query: 326 CTHGINSFRCQCPAGFGGPTCETAQSPCDTKEC-QHGGQCQVENGSAVCVCQAGYTGAAC 384
C R C A G C+ C++ C GG C + G C+A C
Sbjct: 1387 CP------RAACQAKRGDQRCD---RECNSPGCGWDGGDCSLSVGDPWRQCEA----LQC 1433
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
++ DP + +C L N+ C G R T + C A G C
Sbjct: 1434 WRLFNNSRCDPACSSPAC--LYDNFDC-----HAGGRERTCNPVYEKYC--ADHFADGRC 1484
Query: 445 VDADQGYVCECPE-GFMGLDCRERVP 469
DQG C E G+ GLDC VP
Sbjct: 1485 ---DQG--CNTEECGWDGLDCASEVP 1505
Score = 46.2 bits (108), Expect = 2e-04
Identities = 25/70 (35%), Positives = 29/70 (41%), Gaps = 9/70 (12%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCT---RLFSETKAFPV-- 1365
C PC+ GGTC C C PG +GR+CEL PC R S PV
Sbjct: 738 CESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCS 797
Query: 1366 ----WEGGVC 1371
W+G C
Sbjct: 798 CPQGWQGPRC 807
Score = 45.1 bits (105), Expect = 5e-04
Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Query: 1311 CSENPCQNGGTCVPGAD-AHSCDCGPGFKGRRCEL 1344
C+ +PC+NGGTC D + C C PGF+G+ CE+
Sbjct: 201 CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEV 235
Score = 43.1 bits (100), Expect = 0.002
Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
+CS +PC +G CV G + SC C PG+ G RCE + S+PC
Sbjct: 548 DCSPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQVDECRSQPC 591
Score = 42.0 bits (97), Expect = 0.004
Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C +PC NGG C + SC C GF G C+L + S PC
Sbjct: 473 CQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPC 516
Score = 42.0 bits (97), Expect = 0.004
Identities = 14/33 (42%), Positives = 19/33 (57%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C+ PC+NG CV D + C C GF+G C+
Sbjct: 511 CASTPCRNGAKCVDQPDGYECRCAEGFEGTLCD 543
Score = 41.2 bits (95), Expect = 0.007
Identities = 20/43 (46%), Positives = 23/43 (53%), Gaps = 6/43 (13%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
CS PCQNGG CV C C PG+ GR C++ S PC
Sbjct: 1004 CSRQPCQNGGRCVQ--TGAYCLCPPGWSGRLCDIR----SLPC 1040
Score = 41.2 bits (95), Expect = 0.007
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C PCQ+GGTC + C+C PG+ G CE
Sbjct: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCE 1120
Score = 40.8 bits (94), Expect = 0.009
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 3/51 (5%)
Query: 1306 NVPGNCSENPCQNGGTCVPGADAHS-CDCGPGFKGRRC--ELACIKVSRPC 1353
++P C +PC +G C G D C C PG++GR C ++ +V PC
Sbjct: 118 SLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPC 168
Score = 40.8 bits (94), Expect = 0.009
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 1296 LPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
LP + + + C+ PCQ+GG+C+ + C C PG G CE+
Sbjct: 1111 LPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEI 1159
Score = 40.0 bits (92), Expect = 0.016
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
+C + C NGGTCV G + ++C C P + G+ C
Sbjct: 239 DCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 271
Score = 38.9 bits (89), Expect = 0.035
Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 9/51 (17%)
Query: 1311 CSENPCQNGGTCVP-----GADAHSCDCGPGFKGRRCELACIKVSRPCTRL 1356
C PCQ+GG C P G +C C F G RCE +V+R C L
Sbjct: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE----RVARSCREL 1296
Score = 38.1 bits (87), Expect = 0.060
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 1/45 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPCT 1354
C PC++GG C+ D + C C G G CE+ S PCT
Sbjct: 586 CRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCT 630
Score = 38.1 bits (87), Expect = 0.060
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 12/62 (19%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
+C+ NPC G C G + + C C PGF G C + +E + P EGG
Sbjct: 623 DCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVE-----------INECASSPCGEGG 670
Query: 1370 VC 1371
C
Sbjct: 671 SC 672
Score = 37.7 bits (86), Expect = 0.079
Identities = 19/42 (45%), Positives = 25/42 (59%), Gaps = 3/42 (7%)
Query: 1314 NPCQNGGTC--VPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
+PC NGG C +P +A +C C PG+ G RC+L S PC
Sbjct: 47 SPCANGGRCTQLPSREA-ACLCPPGWVGERCQLEDPCHSGPC 87
Score = 37.4 bits (85), Expect = 0.10
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
NPC++ G CV + C CG G+ G RCE + +S PC
Sbjct: 400 NPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPC 440
Score = 37.4 bits (85), Expect = 0.10
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 11/61 (18%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
C PC+N TC+ +C C GF G CE+ E ++ P GGV
Sbjct: 435 CLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVD-----------IDECQSSPCVNGGV 483
Query: 1371 C 1371
C
Sbjct: 484 C 484
Score = 37.4 bits (85), Expect = 0.10
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 4/43 (9%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
C+ +PC GG+CV G + C C PG C+ S PC
Sbjct: 661 CASSPCGEGGSCVDGENGFRCLCPPG----SLPPLCLPPSHPC 699
Score = 36.6 bits (83), Expect = 0.18
Identities = 25/94 (26%), Positives = 34/94 (36%), Gaps = 16/94 (17%)
Query: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRCE--------LACIKVSRPCTRLFSETKAFPV 1365
N C NGGTC HSC C G+ G C C + R+ S A P+
Sbjct: 283 NACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPM 342
Query: 1366 WEGGVCHHVYKRVYRVHQDICFKESCESTSLKKT 1399
+ G+ H+ D C C ++ T
Sbjct: 343 GKTGLLCHL--------DDACVSNPCHEDAICDT 368
Score = 36.2 bits (82), Expect = 0.23
Identities = 19/48 (39%), Positives = 21/48 (43%)
Query: 1296 LPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
L E D G P S C + GTCV C C PG+ G RCE
Sbjct: 1156 LCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203
Score = 36.2 bits (82), Expect = 0.23
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 6/45 (13%)
Query: 1305 GNVPG----NCSENPCQNGGTCVPG--ADAHSCDCGPGFKGRRCE 1343
G+ PG +C+ PC +GG+C P A C C G+ G RCE
Sbjct: 1329 GSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE 1373
Score = 35.8 bits (81), Expect = 0.30
Identities = 18/47 (38%), Positives = 20/47 (42%), Gaps = 4/47 (8%)
Query: 1311 CSENPCQNGGTC----VPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
C PC G C V G SC C GF+G C L +S PC
Sbjct: 82 CHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPC 128
Score = 35.4 bits (80), Expect = 0.39
Identities = 18/57 (31%), Positives = 24/57 (42%), Gaps = 11/57 (19%)
Query: 1315 PCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVC 1371
PC++GGTC+ + C C G+ G CE + PC P GG C
Sbjct: 167 PCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAV----PCA-------PSPCRNGGTC 212
Score = 35.4 bits (80), Expect = 0.39
Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 3/35 (8%)
Query: 1311 CSENPCQNGGTC--VPGADAHSCDCGPGFKGRRCE 1343
C+ NPC++GG C PG C C G++G RC+
Sbjct: 775 CTPNPCEHGGRCESAPG-QLPVCSCPQGWQGPRCQ 808
Score = 34.3 bits (77), Expect = 0.87
Identities = 14/33 (42%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C NPC GTC + +C C PG+ G CE
Sbjct: 891 CLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCE 922
Score = 34.3 bits (77), Expect = 0.87
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 7/68 (10%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSR-PCTR--LFSETKAF---- 1363
C PC +GG C C C F G +C+ SR PC +T A+
Sbjct: 966 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCP 1025
Query: 1364 PVWEGGVC 1371
P W G +C
Sbjct: 1026 PGWSGRLC 1033
Score = 33.9 bits (76), Expect = 1.1
Identities = 21/59 (35%), Positives = 23/59 (38%), Gaps = 11/59 (18%)
Query: 1313 ENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVC 1371
E CQ GG CV +H C C G G CE + PC A P GG C
Sbjct: 1052 EQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE----QEVDPCL-------AQPCQHGGTC 1099
Score = 32.3 bits (72), Expect = 3.3
Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 4/46 (8%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK---VSRPC 1353
C+ PC +G C C C PG+ G RC + + S+PC
Sbjct: 699 CAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPC 743
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 427 bits (1098), Expect = e-119
Identities = 240/674 (35%), Positives = 314/674 (46%), Gaps = 65/674 (9%)
Query: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQP--CQNGGTCTHGINSFR 334
PC+NGG C+ P C C GF G C DVNEC P C G +C + + SF+
Sbjct: 164 PCVNGGVCL----ATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ 219
Query: 335 CQCPAGFGGPTCETAQSPCDTKECQHGGQCQV----ENGSAVCVCQAGYTGAACEMDVDD 390
C CP G GP CE PC + C +GG CQ+ ++ +C+C G+ G CE++ D+
Sbjct: 220 CLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDN 279
Query: 391 CSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAP--CHNGGTCVDAD 448
C C NGG+C D + YTCLC E + G C V + P C NGGTC ++
Sbjct: 280 CVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS---EDVDECETQGPPHCRNGGTCQNSA 336
Query: 449 QGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLG-ANTTLCQCPLGFFGLLCEFE-- 502
+ C C G+ G C E + DDC C G C+ + C CP G GLLC E
Sbjct: 337 GSFHCVCVSGWGGTSCEENL-DDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDM 395
Query: 503 ITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNA-------SHSLPSPCDSDPCFNGGS 555
+ PC+ + QC GS LC+C ++ L + PC +GGS
Sbjct: 396 CLSQPCHGDAQCSTNPLT----GSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGS 451
Query: 556 CDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHC 615
C S+ C CP G+ G CE A + C S PC G TC + +HC CP G+ C
Sbjct: 452 CLNTPGSFNCLCPPGYTGSRCE-ADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLC 510
Query: 616 EIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDR 675
E+ + + CAS PC N C + ++C C PGFSG CE C SPC NGG C+D+
Sbjct: 511 EV-ETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 569
Query: 676 DTDFFCHCQAGYMGRRCQAEVD--CGPPEEVKHATLRFNGTRLGAVALYACDRGYS---- 729
F C C G+ G RCQ EVD P V + L G C G++
Sbjct: 570 PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA-----FFCLCPSGFTGQLC 624
Query: 730 ---LSAPSRIRVCQPHGVWSEPPQ---CLEIDEC------RSQPCLHGGSCQDRVAGYLC 777
L AP+ +CQP + + CL D H G CQ C
Sbjct: 625 EVPLCAPN---LCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS----C 677
Query: 778 LCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSP 837
+C G+ G CE E C + PC +GG+C P Y C CP G+ G C E+ AC S P
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
Query: 838 CQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 897
C +GG C G Y C CP S G C+T +D C S+PC G C+ G+ SC C +G+
Sbjct: 738 CLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGF 797
Query: 898 TGEDCAKELFPPTA 911
G C +L P A
Sbjct: 798 QGPRCEGKLRPSCA 811
Score = 413 bits (1062), Expect = e-115
Identities = 253/729 (34%), Positives = 308/729 (42%), Gaps = 118/729 (16%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQC 337
C G+C +G P CSC+ G+TG +C L + C++ PC NGG C +C C
Sbjct: 127 CSKRGRCHIQA-SGRPQ--CSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQCHC 182
Query: 338 PAGFGGPTCETAQSPC--DTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDP 395
P GF G CE + C D C G C GS C+C G G CE+ C P
Sbjct: 183 PPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRG 242
Query: 396 CLNGGSCVDLVGN----YTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGY 451
C NGG+C + + CLC F G CE PD C+S C NGGTC D Y
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----PDNCVSHQCQNGGTCQDGLDTY 298
Query: 452 VCECPEGFMGLDCRERVPDDCE------CRNGGRCL-GANTTLCQCPLGFFGLLCEFEIT 504
C CPE + G DC E V D+CE CRNGG C A + C C G+ G CE +
Sbjct: 299 TCLCPETWTGWDCSEDV-DECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLD 357
Query: 505 AMPCNMNTQCPDGGYCMEHGGSYLCVCHTD------HNASHSLPSPCDSD---------- 548
C T C G C++ GS+ C+C H L PC D
Sbjct: 358 --DCIAAT-CAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTG 414
Query: 549 ------------------------------PCFNGGSCDAHDDSYTCECPRGFHGKHCEK 578
PC +GGSC S+ C CP G+ G CE
Sbjct: 415 STLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCE- 473
Query: 579 ARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYI 638
A + C S PC G TC + +HC CP G+ CE+ + + CAS PC N C +
Sbjct: 474 ADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV-ETNECASAPCLNHADCHDLL 532
Query: 639 GKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD- 697
++C C PGFSG CE C SPC NGG C+D+ F C C G+ G RCQ EVD
Sbjct: 533 NGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDE 592
Query: 698 -CGPPEEVKHATLRFNGT-----------RLGAVALYA--------------------CD 725
P V + L G +L V L A C
Sbjct: 593 CLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCP 652
Query: 726 RGYSLSAPSRIRVCQPHG-----------VWSEPPQCLEIDECRSQPCLHGGSCQDRVAG 774
G AP HG W+ P E+ C S PC HGG+C + +G
Sbjct: 653 DGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG 712
Query: 775 YLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACD 834
Y C C TGY G C E C + PC NGGSC PG Y C CP G C+T D C
Sbjct: 713 YNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCV 772
Query: 835 SSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDP-CFSSPCGGRGYCLASNGSHSCTC 893
S+PC +GG C + G + C+C F G CE P C SPC R C S C C
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLC 832
Query: 894 KVGYTGEDC 902
GYTG C
Sbjct: 833 PTGYTGGSC 841
Score = 413 bits (1061), Expect = e-115
Identities = 233/699 (33%), Positives = 310/699 (44%), Gaps = 85/699 (12%)
Query: 261 RVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNEC----- 315
R G H +CL+ +PC +C + +TG S C C G++G CH D++EC
Sbjct: 385 RTGLLCHLEDMCLS-QPCHGDAQCSTNPLTG--STLCLCQPGYSGPTCHQDLDECLMAQQ 441
Query: 316 ASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVC 375
PC++GG+C + SF C CP G+ G CE + C ++ C G C + C+C
Sbjct: 442 GPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLC 501
Query: 376 QAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLS 435
G G CE++ ++C+ PCLN C DL+ + C+C F G RCE D C S
Sbjct: 502 PPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDI----DECRS 557
Query: 436 APCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGA-NTTLCQCP 491
+PC NGG C D + C+C GF G C+ V D+C C G CL C CP
Sbjct: 558 SPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV-DECLSDPCPVGASCLDLPGAFFCLCP 616
Query: 492 LGFFGLLCEFEITA------------MPCNMNTQCPDGGY-CMEHGGSYLCVCHTDHNAS 538
GF G LCE + A N CPDG C + C CH H
Sbjct: 617 SGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDN--CTCHHGHCQR 674
Query: 539 HSLPSP--------------CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLC 584
S C S PC +GG+C Y C CP G+ G C + C
Sbjct: 675 SSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMT-AC 733
Query: 585 SSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCD 644
SGPC NGG+C + G Y+C+CP TG C+ D C S PC NGGTC + G + C
Sbjct: 734 HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTST-DYCVSAPCFNGGTCVNRPGTFSCL 792
Query: 645 CPPGFSGRHCE--IAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD-CGPP 701
C GF G CE + PS C SPC N TC+D C C GY G CQ +D C
Sbjct: 793 CAMGFQGPRCEGKLRPS-CADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQK 851
Query: 702 EEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECR--- 758
+++ G + L W+ P L + C+
Sbjct: 852 PCPRNSHCLQTGPSFHCLCLQG---------------------WTGPLCNLPLSSCQKAA 890
Query: 759 -------SQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPG 811
S C +GG C D Y C C G++G+ C+ + C + PC+NG +C P
Sbjct: 891 LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPS 950
Query: 812 AYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPC 871
Y+C+C G+ G +C E+DAC S PC + G C G + C CP F G CE D C
Sbjct: 951 GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC 1010
Query: 872 FSSPC--GGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
PC G C + + C C G+TG+ C E+ P
Sbjct: 1011 LDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP 1049
Score = 348 bits (894), Expect = 2e-95
Identities = 211/635 (33%), Positives = 282/635 (44%), Gaps = 63/635 (9%)
Query: 318 QPCQNGGTCTH-GINSFRCQCPAGFGGPTCETAQSPCDTKE-CQHGGQCQVE-------- 367
+PC NGGTC + CQC GF G TC+ PC + CQ+GG CQ
Sbjct: 33 EPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD-PCQNAQLCQNGGSCQALLPAPLGLP 91
Query: 368 ------NGSAVCVCQAGYTGAACEMDVDD-CSPDPCLNGGSC-VDLVGNYTCLCAEPFKG 419
S +C C G+TG C+ ++D C P C G C + G C C + G
Sbjct: 92 SSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151
Query: 420 LRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC-----EC 474
+C+ + D C + PC NGG C+ C CP GF G C ER ++C C
Sbjct: 152 EQCQ-----LRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHAC-ERDVNECFQDPGPC 205
Query: 475 RNGGRCLGA-NTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCM----EHGGSYLC 529
G C + C CP+G G CE + A PC C +GG C + +LC
Sbjct: 206 PKGTSCHNTLGSFQCLCPVGQEGPRCE--LRAGPCPPRG-CSNGGTCQLMPEKDSTFHLC 262
Query: 530 VCHTDHNASHSLPSP--CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSG 587
+C +P C S C NGG+C D+YTC CP + G C + + G
Sbjct: 263 LCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQG 322
Query: 588 P--CRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDC 645
P CRNGGTC+ + G +HC C + G CE D C + C G TC +G + C C
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-DDCIAATCAPGSTCIDRVGSFSCLC 381
Query: 646 PPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDT--DFFCHCQAGYMGRRCQAEVDCGPPEE 703
PPG +G C + C PC C C CQ GY G C ++D
Sbjct: 382 PPGRTGLLCHLEDM-CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD------ 434
Query: 704 VKHATLRFNGTRLGAVALYACDRGYS-LSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPC 762
+ G C+ G S L+ P P G + + +EC SQPC
Sbjct: 435 --ECLMAQQGPS-------PCEHGGSCLNTPGSFNCLCPPGYTGSRCEA-DHNECLSQPC 484
Query: 763 LHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFV 822
G +C D +A + CLC G EG CE+E +EC + PC N C +L + C C GF
Sbjct: 485 HPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS 544
Query: 823 GVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYC 882
G CE ++D C SSPC +GG+C+ GA+ C C F G C+T D C S PC C
Sbjct: 545 GTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASC 604
Query: 883 LASNGSHSCTCKVGYTGEDCAKELFPPTALKMERV 917
L G+ C C G+TG+ C L P + +++
Sbjct: 605 LDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQI 639
Score = 338 bits (866), Expect = 3e-92
Identities = 229/760 (30%), Positives = 300/760 (39%), Gaps = 143/760 (18%)
Query: 266 GHTTSVCLA------LRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQP 319
G+T S C A +PC G C+D T + C C G G+ C ++ NECAS P
Sbjct: 466 GYTGSRCEADHNECLSQPCHPGSTCLDLLAT----FHCLCPPGLEGQLCEVETNECASAP 521
Query: 320 CQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379
C N C +N F+C C GF G CE C + C +GGQCQ + G+ C C G+
Sbjct: 522 CLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGF 581
Query: 380 TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCL--------------------------- 412
G C+ +VD+C DPC G SC+DL G + CL
Sbjct: 582 EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICK 641
Query: 413 ----------------CAEPFKGLRCETGD-------------HPVPDA----CLSAPCH 439
CA P C G P +A C+SAPC
Sbjct: 642 DQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCA 701
Query: 440 NGGTCVDADQGYVCECPEGFMGLDCRERVP--DDCECRNGGRCLGA-NTTLCQCPLGFFG 496
+GGTC GY C CP G+ G C E + C NGG C + C CP G
Sbjct: 702 HGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTG 761
Query: 497 LLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASH---SLPSPCDSDPCFNG 553
C+ T+ ++ C +GG C+ G++ C+C L C PC N
Sbjct: 762 PQCQ---TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNR 818
Query: 554 GSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGR 613
+C C CP G+ G C+ LC+ PC C + G +HC C +TG
Sbjct: 819 ATCQDSPQGPRCLCPTGYTGGSCQTLMD-LCAQKPCPRNSHCLQTGPSFHCLCLQGWTGP 877
Query: 614 HCEIGKPDSC----------ASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFR 663
C + SC S CHNGG C Y C CPPGF G C+ +PC
Sbjct: 878 LCNLPL-SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCES 936
Query: 664 SPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD------------CGPPEEVKHATLR- 710
PC NG TC + + + C C GY G+ C E+D C P H
Sbjct: 937 RPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 711 -FNGTRLGAVALYACDRG---------YSLSAPSRIRVCQPH-GVWSEPPQCLEIDECRS 759
F G R D+ +SL+ + H G W E +EID C S
Sbjct: 997 GFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCE----VEIDPCHS 1052
Query: 760 QPCLHGGSCQDRVA---GYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYV-- 814
QPC HGG+C+ G++C C G+EG C C H C +GG C P
Sbjct: 1053 QPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPP 1112
Query: 815 -CRCPAGFVGVHCETEV--DACDS-SPCQHGGRCES----GGGAYLCVCPESFFGYHCET 866
C C +G+ G C T C SPC + G C GG + C CP S G C+
Sbjct: 1113 RCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQK 1172
Query: 867 VSDPCFSSPCGGRGYCLASNGSHSCTCK---VGYTGEDCA 903
+ C GR + +G+ C + G DC+
Sbjct: 1173 PG----AKGCEGR----SGDGACDAGCSGPGGNWDGGDCS 1204
Score = 215 bits (548), Expect = 2e-55
Identities = 159/549 (28%), Positives = 207/549 (37%), Gaps = 134/549 (24%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPS---YTCSCLSGFTGRRCHLDVNECASQPCQ 321
C + C + PCLNGG C NPS Y C+C TG +C + C S PC
Sbjct: 726 CSEEMTACHS-GPCLNGGSC-------NPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCF 777
Query: 322 NGGTCTHGINSFRCQCPAGFGGPTCETAQSP-CDTKECQHGGQCQVENGSAVCVCQAGYT 380
NGGTC + +F C C GF GP CE P C C++ CQ C+C GYT
Sbjct: 778 NGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYT 837
Query: 381 GAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLS----- 435
G +C+ +D C+ PC C+ ++ CLC + + G C A LS
Sbjct: 838 GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDV 897
Query: 436 -APCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGANTT-LCQC 490
+ CHNGG CVD+ Y C CP GF G C++ V + CE C+NG C+ + LCQC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHV-NPCESRPCQNGATCMAQPSGYLCQC 956
Query: 491 PLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCH------------------ 532
G+ G C E+ A + C + G C G + C C
Sbjct: 957 APGYDGQNCSKELDAC---QSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ 1013
Query: 533 ----TDHNASHSLPS--------------------PCDSDPCFNGGSCDAHDDS---YTC 565
T A HSL + PC S PCF+GG+C+A S + C
Sbjct: 1014 PCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFIC 1073
Query: 566 ECPRGFHGKHCEKARP----HLCSSG---------------------------------- 587
CP+GF G C P H C G
Sbjct: 1074 HCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG 1133
Query: 588 -----PCRNGGTCKEAGG----EYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYI 638
PC G+C E G + CSCP+ G C+ KP + G C
Sbjct: 1134 CGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ--KPGAKGCEGRSGDGAC---- 1187
Query: 639 GKYKCDCPPG-FSGRHCEI-APSPCFRSPCVNGGTCEDRDTDFFCHCQAG-----YMGRR 691
C P G + G C + P P C + C D CH Q + G
Sbjct: 1188 -DAGCSGPGGNWDGGDCSLGVPDPW--KGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYD 1244
Query: 692 CQAEVDCGP 700
C+ C P
Sbjct: 1245 CETPPACTP 1253
Score = 165 bits (418), Expect = 3e-40
Identities = 119/412 (28%), Positives = 150/412 (36%), Gaps = 110/412 (26%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQC 337
C NGG C+D PSY C C GF G C VN C S+PCQNG TC + + CQC
Sbjct: 901 CHNGGLCVDS----GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC 956
Query: 338 PAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCL 397
G+ G C C ++ C + G C + G C C G+ G CE DVD+C PC
Sbjct: 957 APGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCH 1016
Query: 398 NGGS--CVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC---VDADQGYV 452
G+ C L + C C G CE P C S PC +GGTC + G++
Sbjct: 1017 PTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP----CHSQPCFHGGTCEATAGSPLGFI 1072
Query: 453 CECPEGFMGLDCRERVPD----------------------DCECRNG------------- 477
C CP+GF G C R P C C +G
Sbjct: 1073 CHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPK 1132
Query: 478 -----------GRC-----LGANTTLCQCPLGFFGLLC--------EFEITAMPCNMNTQ 513
G C LG C CP G C E C+
Sbjct: 1133 GCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCS 1192
Query: 514 CPDGGY---------------CMEHGGSYLCV----CHTDHNASHSLPSPCDSDPC-FNG 553
P G + C H +L CH CDS+ C F+G
Sbjct: 1193 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQ----------CDSEECLFDG 1242
Query: 554 GSCD---AHDDSYTCECPRGFHGKHCEKARPHLCSSGPCR-NGGTCKEAGGE 601
C+ A +Y C FH HCEK C++ C +GG C+ G+
Sbjct: 1243 YDCETPPACTPAYDQYCHDHFHNGHCEKG----CNTAECGWDGGDCRPEDGD 1290
Score = 131 bits (330), Expect = 4e-30
Identities = 94/333 (28%), Positives = 122/333 (36%), Gaps = 95/333 (28%)
Query: 662 FRSPCVNGGTCEDRDT-DFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAV- 719
F PC NGGTC C C G++G CQ P+ ++A L NG A+
Sbjct: 31 FPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF------PDPCQNAQLCQNGGSCQALL 84
Query: 720 -ALYACDRGYSLSAPSRIRVCQPHGVWSE----------PP------------------- 749
A S PS + C P G E PP
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLP-GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC 143
Query: 750 ---------QCLEIDECRSQPCLHGG---------------------------------- 766
QC D C + PC++GG
Sbjct: 144 SCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPG 203
Query: 767 ------SCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGA----YVCR 816
SC + + + CLC G EG CEL C C NGG+C+ +P ++C
Sbjct: 204 PCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263
Query: 817 CPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSS-- 874
CP GF+G CE D C S CQ+GG C+ G Y C+CPE++ G+ C D C +
Sbjct: 264 CPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGP 323
Query: 875 -PCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
C G C S GS C C G+ G C + L
Sbjct: 324 PHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL 356
Score = 46.2 bits (108), Expect = 2e-04
Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 3/48 (6%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL---ACIKVSRPCTR 1355
CS NPC NGG C+ C C PGF+G CE C + PC +
Sbjct: 160 CSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPK 207
Score = 45.4 bits (106), Expect = 4e-04
Identities = 50/190 (26%), Positives = 64/190 (33%), Gaps = 39/190 (20%)
Query: 264 GCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQ-- 321
GCG + PCL G C + G P + CSC G RC + ++ C+
Sbjct: 1133 GCGPPS-------PCLYNGSCSETTGLGGPGFRCSCPHSSPGPRC----QKPGAKGCEGR 1181
Query: 322 -NGGTCTHGINSFRCQCPAG-FGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379
G C G C P G + G C P K C +C + C Q
Sbjct: 1182 SGDGACDAG-----CSGPGGNWDGGDCSLG-VPDPWKGCPSHSRCWLLFRDGQCHPQC-- 1233
Query: 380 TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPC- 438
C D DC P +C Y C + F CE G C +A C
Sbjct: 1234 DSEECLFDGYDCETPP-----ACTPAYDQY---CHDHFHNGHCEKG-------CNTAECG 1278
Query: 439 HNGGTCVDAD 448
+GG C D
Sbjct: 1279 WDGGDCRPED 1288
Score = 45.1 bits (105), Expect = 5e-04
Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 5/46 (10%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL---ACIKVSRPC 1353
C PCQNG TC+ + C C PG+ G+ C AC S+PC
Sbjct: 934 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDAC--QSQPC 977
Score = 44.7 bits (104), Expect = 6e-04
Identities = 17/33 (51%), Positives = 17/33 (51%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C PC N GTC P C C PGF G RCE
Sbjct: 972 CQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCE 1004
Score = 43.9 bits (102), Expect = 0.001
Identities = 20/47 (42%), Positives = 21/47 (44%)
Query: 1297 PEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
P H C PC NGGTCV SC C GF+G RCE
Sbjct: 757 PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE 803
Score = 43.1 bits (100), Expect = 0.002
Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C +PC NGG C A C C PGF+G RC+ + +S PC
Sbjct: 555 CRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPC 598
Score = 42.0 bits (97), Expect = 0.004
Identities = 22/60 (36%), Positives = 26/60 (43%)
Query: 1283 MEEAPKRVSLALQLPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
M E L L P D P NC + CQNGGTC G D ++C C + G C
Sbjct: 252 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
Score = 40.8 bits (94), Expect = 0.009
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELAC-IKVSRPC 1353
C PC NGG+C P + C C P G +C+ + VS PC
Sbjct: 733 CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPC 776
Score = 40.4 bits (93), Expect = 0.012
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 1309 GNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
G C PC +GGTC P ++C C G+ G C
Sbjct: 693 GGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTC 726
Score = 40.0 bits (92), Expect = 0.016
Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 5/43 (11%)
Query: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRCEL---ACIKVSRPC 1353
+PC++GG+C+ + +C C PG+ G RCE C+ S+PC
Sbjct: 444 SPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECL--SQPC 484
Score = 38.5 bits (88), Expect = 0.046
Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Query: 1300 GSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE-LACIKVSRPCTR 1355
G + G + +C+++PC+N TC C C G+ G C+ L + +PC R
Sbjct: 799 GPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPR 855
Score = 38.5 bits (88), Expect = 0.046
Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 5/41 (12%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCE---LACIKVSRPC 1353
C NGG CV ++ C C PGF+G C+ C SRPC
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC--ESRPC 939
Score = 38.1 bits (87), Expect = 0.060
Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 4/40 (10%)
Query: 1309 GNCSENPCQNGGTC--VPGADA--HSCDCGPGFKGRRCEL 1344
G C C NGGTC +P D+ H C C PGF G CE+
Sbjct: 236 GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEV 275
Score = 37.4 bits (85), Expect = 0.10
Identities = 16/44 (36%), Positives = 22/44 (50%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
+C C G TC+ + SC C PG G C L + +S+PC
Sbjct: 358 DCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
Score = 36.2 bits (82), Expect = 0.23
Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Query: 1315 PCQNGGTCVP-GADAHSCDCGPGFKGRRCE 1343
PC NGGTC+ +C C PGF G C+
Sbjct: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQ 63
Score = 35.8 bits (81), Expect = 0.30
Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C PC G TC+ C C PG +G+ CE+ + S PC
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPC 522
Score = 35.4 bits (80), Expect = 0.39
Identities = 19/61 (31%), Positives = 23/61 (37%), Gaps = 11/61 (18%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
C+ PC N C + C C PGF G RCE E ++ P GG
Sbjct: 517 CASAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQ 565
Query: 1371 C 1371
C
Sbjct: 566 C 566
Score = 34.3 bits (77), Expect = 0.87
Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 13/69 (18%)
Query: 1311 CSENPCQNGGTC-VPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
C + C G C + + C C PG+ G +C+L + PC GG
Sbjct: 122 CPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCV------------NGG 169
Query: 1370 VCHHVYKRV 1378
VC Y ++
Sbjct: 170 VCLATYPQI 178
Score = 34.3 bits (77), Expect = 0.87
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 16/84 (19%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCE--------LACIKVSRPCTRLFSETKAFPVWE 1367
C+NGGTC A + C C G+ G CE C S R+ S + P
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGR 385
Query: 1368 GGVCHHVYKRVYRVHQDICFKESC 1391
G+ H+ +D+C + C
Sbjct: 386 TGLLCHL--------EDMCLSQPC 401
Score = 33.9 bits (76), Expect = 1.1
Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 24/71 (33%)
Query: 1316 CQNGGTCV--------------PGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETK 1361
CQNGG+C P + C C PGF G RC+ K+ PC F +
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQ---AKLEDPCPPSFCSKR 130
Query: 1362 AFPVWEGGVCH 1372
G CH
Sbjct: 131 -------GRCH 134
Score = 33.1 bits (74), Expect = 1.9
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 13/63 (20%)
Query: 1311 CSENPCQNGGT--CVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEG 1368
C + PC GT C A+A C C PG G+ CE+ PC + P + G
Sbjct: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI----DPC-------HSQPCFHG 1058
Query: 1369 GVC 1371
G C
Sbjct: 1059 GTC 1061
Score = 32.7 bits (73), Expect = 2.5
Identities = 13/34 (38%), Positives = 18/34 (52%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C +PC G +C+ A C C GF G+ CE+
Sbjct: 593 CLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEV 626
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 387 bits (994), Expect = e-107
Identities = 216/660 (32%), Positives = 300/660 (45%), Gaps = 80/660 (12%)
Query: 283 KCIDD--CVTG--NPSYTCSCLSGFTGRRCHLDVNECAS-QPCQNGGTCTH-GINSFRCQ 336
KCI CV G N + C C + + G+ C D+N C + QPC NGGTC++ G + ++C
Sbjct: 264 KCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCS 323
Query: 337 CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPC 396
CP G+ GP CE A+ C + C + G C+ + C C G+TG C ++DDCSP+ C
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNC 383
Query: 397 LNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECP 456
+GG+C DLV + C+C + G C+ + C + PC N +C + Y C+C
Sbjct: 384 SHGGTCQDLVNGFKCVCPPQWTGKTCQLD----ANECEAKPCVNAKSCKNLIASYYCDCL 439
Query: 457 EGFMGLDCRERVPDDC--ECRNGGRCLG-ANTTLCQCPLGFFGLLCEFEITAMPCNMNTQ 513
G+MG +C + +DC +C+N C N C CP G+ G CE +I N
Sbjct: 440 PGWMGQNCDINI-NDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASN---P 495
Query: 514 CPDGGYCMEHGGSYLCVCHT--DHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGF 571
C +GG+C + C+C T N C+ +PC NG C Y C+CP +
Sbjct: 496 CLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 572 HGKHCEKARPH--------------------------LCSSGPCRNGGTCK-EAGGEYHC 604
GK+C + H SS C G CK ++GG++ C
Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615
Query: 605 SCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRS 664
C FTG +C D C S PC NGGTC + YKC C G+ G +CE + C ++
Sbjct: 616 DCNKGFTGTYCHENIND-CESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN 674
Query: 665 PCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYAC 724
PC NGGTC D DF+C C+ G+ G+ C + + AT GT
Sbjct: 675 PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSR-----DSQCDEATCNNGGT--------CY 721
Query: 725 DRGYSLSAPSRIRVCQPHGVWSEPPQC--LEIDECRSQPCLHGGSCQDRVAGYLCLCSTG 782
D G + C G W E C C PC +GG+C + C+C G
Sbjct: 722 DEGDAFK-------CMCPGGW-EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEG 773
Query: 783 YEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGG 842
+EG C ++C HPC N G+C + Y C C GF G C ++ C SSPC G
Sbjct: 774 WEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGA 833
Query: 843 RCESGGGAYLCVCPESFFGYHCETVSD-PCFSS----PCGGR-----GYCLASNGSHSCT 892
C Y CVCP G C+ VS PC + P G + C NG +C+
Sbjct: 834 TCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
Score = 371 bits (953), Expect = e-102
Identities = 223/709 (31%), Positives = 296/709 (41%), Gaps = 104/709 (14%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C + C +PCLNGG C + TG Y CSC G++G C + + C S PC N G
Sbjct: 293 CDKDLNYCGTHQPCLNGGTCSN---TGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRG 349
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
+C F C+C G+ GPTC T C C HGG CQ CVC +TG C
Sbjct: 350 SCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTC 409
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
++D ++C PC+N SC +L+ +Y C C + G C+ + CL C N +C
Sbjct: 410 QLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININD----CL-GQCQNDASC 464
Query: 445 VDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLG-ANTTLCQCPLGFFGLLCE 500
D GY C CP G+ G C ER D+C C NGG C N C CP GF G LC+
Sbjct: 465 RDLVNGYRCICPPGYAGDHC-ERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ 523
Query: 501 FEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTD-------HNASHSLPSPCD------- 546
+I C N C +G C Y C C D H H +PC+
Sbjct: 524 LDIDY--CEPN-PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTV 580
Query: 547 ---------------SDPCFNGGSCDAHD-DSYTCECPRGFHGKHCEKARPHLCSSGPCR 590
S+ C G C + +TC+C +GF G +C + + C S PCR
Sbjct: 581 AMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE-NINDCESNPCR 639
Query: 591 NGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFS 650
NGGTC + Y C C + G +CE D C+ PCHNGGTC + + CDC G+
Sbjct: 640 NGGTCIDGVNSYKCICSDGWEGAYCETNIND-CSQNPCHNGGTCRDLVNDFYCDCKNGWK 698
Query: 651 GRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLR 710
G+ C S C + C NGGTC D F C C G+ G C
Sbjct: 699 GKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTC------------------ 740
Query: 711 FNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQD 770
N R + C G + C W P ++C PC + G+C D
Sbjct: 741 -NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVD 799
Query: 771 RVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEV 830
Y C C+ G+ G C + +EC++ PC G +C + Y C CP G G C+ EV
Sbjct: 800 GDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ-EV 858
Query: 831 -------------------DACDSSPCQHG--GRCESGGGAYLCV-------CPESFFGY 862
D C++ C +G + G C+ CP G
Sbjct: 859 SGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPS---GQ 915
Query: 863 HC-ETVSDPCFSSPCGGRGYCLASN---GSHSCTCKVGYTGEDCAKELF 907
C + D CF PC G G C +S+ CT Y ++CA F
Sbjct: 916 SCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSD-SYYQDNCANITF 963
Score = 267 bits (683), Expect = 5e-71
Identities = 154/498 (30%), Positives = 222/498 (44%), Gaps = 89/498 (17%)
Query: 451 YVCE------CPEGFMGLDCRERV-PDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEI 503
Y C+ C EG+MG +C + C ++G L + C+C G+ GL C+
Sbjct: 210 YACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGD---CRCQYGWQGLYCD--- 263
Query: 504 TAMP--------CNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGS 555
+P CN QC C + G LC ++ +H PC NGG+
Sbjct: 264 KCIPHPGCVHGICNEPWQC----LCETNWGGQLCDKDLNYCGTH--------QPCLNGGT 311
Query: 556 C-DAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRH 614
C + D Y C CP G+ G +CE A H C S PC N G+CKE + C C +TG
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAE-HACLSDPCHNRGSCKETSLGFECECSPGWTGPT 370
Query: 615 CEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCED 674
C D C+ C +GGTC + +KC CPP ++G+ C++ + C PCVN +C++
Sbjct: 371 CST-NIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKN 429
Query: 675 RDTDFFCHCQAGYMGRRCQAEV-DC-GPPEEVKHATLRFNGTRLGAVALYACDRGYSLSA 732
++C C G+MG+ C + DC G + NG R C GY+
Sbjct: 430 LIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRC------ICPPGYAGDH 483
Query: 733 PSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELER 792
R +IDEC S PCL+GG CQ+ + + CLC TG+ G C+L+
Sbjct: 484 CER-----------------DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDI 526
Query: 793 DECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQ------------- 839
D C +PC+NG C N Y C+CP + G +C D C ++PC+
Sbjct: 527 DYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASND 586
Query: 840 --------------HGGRCES-GGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLA 884
G+C+S GG + C C + F G +C + C S+PC G C+
Sbjct: 587 TPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCID 646
Query: 885 SNGSHSCTCKVGYTGEDC 902
S+ C C G+ G C
Sbjct: 647 GVNSYKCICSDGWEGAYC 664
Score = 49.7 bits (117), Expect = 2e-05
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 11/70 (15%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
+C NPC+NGGTC+ G +++ C C G++G CE ++ P GG
Sbjct: 632 DCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN-----------INDCSQNPCHNGG 680
Query: 1370 VCHHVYKRVY 1379
C + Y
Sbjct: 681 TCRDLVNDFY 690
Score = 48.1 bits (113), Expect = 6e-05
Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
+CS +PC N GTCV G + + C+C PGF G C + + S PC
Sbjct: 785 DCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPC 829
Score = 46.2 bits (108), Expect = 2e-04
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 14/72 (19%)
Query: 1312 SENPCQNGGTCV-PGADAHSCDCGPGFKGRRCEL---ACIKVSRPC--------TRLFSE 1359
+ PC NGGTC G D + C C G+ G CE+ AC+ S PC T L E
Sbjct: 302 THQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACL--SDPCHNRGSCKETSLGFE 359
Query: 1360 TKAFPVWEGGVC 1371
+ P W G C
Sbjct: 360 CECSPGWTGPTC 371
Score = 45.8 bits (107), Expect = 3e-04
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 13/74 (17%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC---ELACIKVSRPCTR---LFSETKAF 1363
+CS+NPC NGGTC + CDC G+KG+ C + C + + C + E AF
Sbjct: 670 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEAT--CNNGGTCYDEGDAF 727
Query: 1364 PV-----WEGGVCH 1372
WEG C+
Sbjct: 728 KCMCPGGWEGTTCN 741
Score = 41.6 bits (96), Expect = 0.005
Identities = 15/33 (45%), Positives = 21/33 (63%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
+C NPC NGGTCV ++ +C C G++G C
Sbjct: 747 SCLPNPCHNGGTCVVNGESFTCVCKEGWEGPIC 779
Score = 41.2 bits (95), Expect = 0.007
Identities = 16/35 (45%), Positives = 19/35 (54%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELA 1345
C E C NGGTC DA C C G++G C +A
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA 743
Score = 40.0 bits (92), Expect = 0.016
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 4/47 (8%)
Query: 1298 EHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
+H +DI C+ NPC NGG C + C C GF G C+L
Sbjct: 482 DHCERDIDE----CASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL 524
Score = 40.0 bits (92), Expect = 0.016
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWE 1367
C +PC G TCV + + C C PG G +C+ RPC + S W+
Sbjct: 824 CQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVS---GRPCITMGSVIPDGAKWD 877
Score = 38.9 bits (89), Expect = 0.035
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 11/72 (15%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL--------ACIKVSRPCTRLFSE-- 1359
+CS N C +GGTC + C C P + G+ C+L C+ ++ C L +
Sbjct: 377 DCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVN-AKSCKNLIASYY 435
Query: 1360 TKAFPVWEGGVC 1371
P W G C
Sbjct: 436 CDCLPGWMGQNC 447
Score = 37.7 bits (86), Expect = 0.079
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
C NPCQNG C A + C C ++G+ C
Sbjct: 529 CEPNPCQNGAQCYNRASDYFCKCPEDYEGKNC 560
Score = 35.4 bits (80), Expect = 0.39
Identities = 12/32 (37%), Positives = 17/32 (53%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
C +PC N G+C + C+C PG+ G C
Sbjct: 340 CLSDPCHNRGSCKETSLGFECECSPGWTGPTC 371
Score = 35.0 bits (79), Expect = 0.51
Identities = 12/34 (35%), Positives = 19/34 (55%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C PC N +C ++ CDC PG+ G+ C++
Sbjct: 416 CEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDI 449
Score = 33.1 bits (74), Expect = 1.9
Identities = 18/62 (29%), Positives = 24/62 (38%), Gaps = 11/62 (17%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCHHVY 1375
CQN +C + + C C PG+ G CE R E + P GG C +
Sbjct: 458 CQNDASCRDLVNGYRCICPPGYAGDHCE-----------RDIDECASNPCLNGGHCQNEI 506
Query: 1376 KR 1377
R
Sbjct: 507 NR 508
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 373 bits (957), Expect = e-103
Identities = 213/683 (31%), Positives = 295/683 (43%), Gaps = 87/683 (12%)
Query: 263 GGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECAS-QPCQ 321
G G C+ C++G C++ + C+C + + G C D+N C S PC
Sbjct: 267 GWQGRFCDECVPYPGCVHGS-CVEP-------WQCNCETNWGGLLCDKDLNYCGSHHPCT 318
Query: 322 NGGTCTHG-INSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYT 380
NGGTC + + +RC CP G+ G CE A+ C + C +GG C C C +G++
Sbjct: 319 NGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS 378
Query: 381 GAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHN 440
G C +D+D+C+ +PC GG+CVD V + C+C E + G C+ + C PC N
Sbjct: 379 GPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLD----ANECEGKPCLN 434
Query: 441 GGTCVDADQGYVCECPEGFMGLDCRERVPDDC--ECRNGGRCLG-ANTTLCQCPLGFFGL 497
+C + GY C+C G+ G++C V +DC +C++GG C N C CP GF G
Sbjct: 435 AFSCKNLIGGYYCDCIPGWKGINCHINV-NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGR 493
Query: 498 LCEF---EITAMPCNMNTQC---PDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCF 551
CE E + PC+ C DG +C G +C D + C+ PC
Sbjct: 494 HCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDL-------CEPSPCR 546
Query: 552 NGGSCDAHDDSYTCECPRGFHGKHCEKAR----------------------PHLCSSGPC 589
NG C + Y C CP F GK+C R P +SG C
Sbjct: 547 NGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVC 606
Query: 590 RNGGTC-KEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPG 648
G C + GG + C C FTG +C D C PC NGGTC + ++C CP G
Sbjct: 607 GPHGRCVSQPGGNFSCICDSGFTGTYCH-ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSG 665
Query: 649 FSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQA-EVDCGPPEEVKHA 707
+ G C+ P+ C PC + G C D DF+C C G+ G+ C + E C
Sbjct: 666 WEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCD-------- 717
Query: 708 TLRFNGTRLGAVALYACDRGYS-LSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGG 766
Y C G + + R P G + C PC++GG
Sbjct: 718 -------------AYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGG 764
Query: 767 SCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHC 826
+C A + C+C G+EG C ++C PC NGG C + + C C GF G C
Sbjct: 765 TCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDC 824
Query: 827 ETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASN 886
+D C SSPC +G C Y C CP G C+ V F C RG
Sbjct: 825 RINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIG--FGRSCWSRGTPFPHG 882
Query: 887 GS-----HSCTCKVGYTGEDCAK 904
S +SC C G DC+K
Sbjct: 883 SSWVEDCNSCRCLDG--RRDCSK 903
Score = 355 bits (912), Expect = 1e-97
Identities = 219/707 (30%), Positives = 296/707 (41%), Gaps = 105/707 (14%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C + C + PC NGG CI+ Y C+C G++GR C + C S PC NGG
Sbjct: 304 CDKDLNYCGSHHPCTNGGTCIN---AEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG 360
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
+C + F C CP+G+ GPTC C + C GG C + C+C + GA C
Sbjct: 361 SCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATC 420
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
++D ++C PCLN SC +L+G Y C C +KG+ C H + C C +GGTC
Sbjct: 421 QLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINC----HINVNDC-RGQCQHGGTC 475
Query: 445 VDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLG-ANTTLCQCPLGFFGLLCE 500
D GY C CP GF G C E D+C C +GG C A+ C CP GF G LCE
Sbjct: 476 KDLVNGYQCVCPRGFGGRHC-ELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE 534
Query: 501 FEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASH-SLP-SPC------------- 545
++ + C +G C G Y C C D + S+P PC
Sbjct: 535 VDVDLCE---PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGS 591
Query: 546 DSDPCFNG----GSCDAH-------DDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGT 594
D+ P G G C H +++C C GF G +C + C PCRNGGT
Sbjct: 592 DAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDD-CLGQPCRNGGT 650
Query: 595 CKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHC 654
C + + C CP + G C+ P+ C PCH+ G C+ + + C C G+ G+ C
Sbjct: 651 CIDEVDAFRCFCPSGWEGELCDT-NPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTC 709
Query: 655 EIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQA--EVDCGPPEEVKHATLRFN 712
C C NGGTC D F C C G+ G C C P V
Sbjct: 710 HSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVN------G 763
Query: 713 GTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRV 772
GT +G+ A ++C +C+ W ++C PC +GG C D V
Sbjct: 764 GTCVGSGASFSC-------------ICRDG--WEGRTCTHNTNDCNPLPCYNGGICVDGV 808
Query: 773 AGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCE----- 827
+ C C+ G+ G C + DEC++ PC G +C + Y C CP G G C+
Sbjct: 809 NWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGF 868
Query: 828 ---------------TEVDACDSSPCQHGGR-----------CESGG--GAYLCVCPESF 859
+ V+ C+S C G R C G A CP
Sbjct: 869 GRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCP--- 925
Query: 860 FGYHC-ETVSDPCFSSPCGGRGYCLASN-GSHSCTCKVGYTGEDCAK 904
G C E C PC G C A S C + G+ +CA+
Sbjct: 926 LGQRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNCAR 972
Score = 271 bits (692), Expect = 4e-72
Identities = 162/489 (33%), Positives = 218/489 (44%), Gaps = 75/489 (15%)
Query: 451 YVCE------CPEGFMGLDCRERVPDDCECRNGGRCLGANTTL---CQCPLGFFGLLCEF 501
Y C+ C +G+MG +C+E V C+ G L T+ C+C G+ G C+
Sbjct: 221 YTCDQYGNKACMDGWMGKECKEAV-----CKQGCNLLHGGCTVPGECRCSYGWQGRFCD- 274
Query: 502 EITAMPCNMNTQC--PDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSC-DA 558
E P ++ C P C + G LC ++ SH PC NGG+C +A
Sbjct: 275 ECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSH--------HPCTNGGTCINA 326
Query: 559 HDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIG 618
D Y C CP G+ G++CEKA H C+S PC NGG+C E + C CP ++G C +
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAE-HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCAL- 384
Query: 619 KPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTD 678
D CAS PC GGTC + ++C CP + G C++ + C PC+N +C++
Sbjct: 385 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGG 444
Query: 679 FFCHCQAGYMGRRCQAEV-DCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIR 737
++C C G+ G C V DC + GT V Y C
Sbjct: 445 YYCDCIPGWKGINCHINVNDC-------RGQCQHGGTCKDLVNGYQC------------- 484
Query: 738 VCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRA 797
VC P G + LE DEC S PC GG C+D G+ C C G+ G CE++ D C
Sbjct: 485 VC-PRGFGGRHCE-LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEP 542
Query: 798 HPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDAC-------------DSSP------- 837
PCRNG C NL G Y C CP F G +C + C D+ P
Sbjct: 543 SPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAA 602
Query: 838 ---CQHGGRCES-GGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTC 893
C GRC S GG + C+C F G +C D C PC G C+ + C C
Sbjct: 603 SGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFC 662
Query: 894 KVGYTGEDC 902
G+ GE C
Sbjct: 663 PSGWEGELC 671
Score = 48.1 bits (113), Expect = 6e-05
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 11/62 (17%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
+C NPC NGGTCV + SC C G++G R CT ++ P + GG
Sbjct: 754 SCLPNPCVNGGTCVGSGASFSCICRDGWEG-----------RTCTHNTNDCNPLPCYNGG 802
Query: 1370 VC 1371
+C
Sbjct: 803 IC 804
Score = 47.4 bits (111), Expect = 1e-04
Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 12/64 (18%)
Query: 1312 SENPCQNGGTCVPGA-DAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
S +PC NGGTC+ D + C C G+ GR CE K CT + P GG
Sbjct: 313 SHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE----KAEHACT-------SNPCANGGS 361
Query: 1371 CHHV 1374
CH V
Sbjct: 362 CHEV 365
Score = 45.8 bits (107), Expect = 3e-04
Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 9/71 (12%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPCTRLFS--------ETK 1361
C+ NPC GGTCV D C C + G C+L + +PC FS
Sbjct: 389 CASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCD 448
Query: 1362 AFPVWEGGVCH 1372
P W+G CH
Sbjct: 449 CIPGWKGINCH 459
Score = 45.1 bits (105), Expect = 5e-04
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
+C+ PC NGG CV G + C+C PGF G C + + S PC
Sbjct: 792 DCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPC 836
Score = 42.4 bits (98), Expect = 0.003
Identities = 15/34 (44%), Positives = 21/34 (61%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
+C PC+NGGTC+ DA C C G++G C+
Sbjct: 639 DCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCD 672
Score = 40.0 bits (92), Expect = 0.016
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C+ +PC +GG C AD C C GF G CE+
Sbjct: 502 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV 535
Score = 39.3 bits (90), Expect = 0.027
Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 11/62 (17%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
N CQ+GGTC + + C C GF GR CEL E + P GG
Sbjct: 463 NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDECASSPCHSGG 511
Query: 1370 VC 1371
+C
Sbjct: 512 LC 513
Score = 39.3 bits (90), Expect = 0.027
Identities = 14/33 (42%), Positives = 18/33 (54%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C +PC G TCV + + C C PG G RC+
Sbjct: 831 CQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQ 863
Score = 38.9 bits (89), Expect = 0.035
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C+ NPC NGG+C C C G+ G C L + S PC
Sbjct: 351 CTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPC 394
Score = 34.3 bits (77), Expect = 0.87
Identities = 13/34 (38%), Positives = 17/34 (50%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C PC N +C + CDC PG+KG C +
Sbjct: 427 CEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHI 460
Score = 34.3 bits (77), Expect = 0.87
Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 11/65 (16%)
Query: 1308 PGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWE 1367
P +C +PC + G C + C C G+KG+ C +R F + A+
Sbjct: 675 PNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCH----------SREF-QCDAYTCSN 723
Query: 1368 GGVCH 1372
GG C+
Sbjct: 724 GGTCY 728
Score = 31.2 bits (69), Expect = 7.4
Identities = 11/34 (32%), Positives = 16/34 (47%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C +PC+NG C + C C F G+ C +
Sbjct: 540 CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSV 573
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 358 bits (919), Expect = 2e-98
Identities = 217/676 (32%), Positives = 293/676 (43%), Gaps = 81/676 (11%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C + C + PC NGG CI+ Y C+C G++GR C + C S PC NGG
Sbjct: 304 CDKDLNYCGSHHPCTNGGTCIN---AEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG 360
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
+C + F C CP+G+ GPTC C + C GG C + C+C + GA C
Sbjct: 361 SCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATC 420
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
++DV+DC C +GG+C DLV Y C+C F G CE D C S+PCH+GG C
Sbjct: 421 QLDVNDCR-GQCQHGGTCKDLVNGYQCVCPRGFGGRHCEL----ERDECASSPCHSGGLC 475
Query: 445 VDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLG-ANTTLCQCPLGFFGLLCE 500
D G+ C CP+GF G C V D CE CRNG RC C CP F G C
Sbjct: 476 EDLADGFHCHCPQGFSGPLCEVDV-DLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCS 534
Query: 501 FEITAMP---CNMNTQC------------------PDGGYCMEHGGSYLCVCHTDHNAS- 538
P C + C P G + GG++ C+C + +
Sbjct: 535 VPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTY 594
Query: 539 -HSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKE 597
H C PC NGG+C D++ C CP G+ G+ C+ P+ C PC + G C +
Sbjct: 595 CHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCD-TNPNDCLPDPCHSRGRCYD 653
Query: 598 AGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIA 657
+++C+C + G+ C + C + C NGGTC+ ++C CPPG+ G C +A
Sbjct: 654 LVNDFYCACDDGWKGKTCH-SREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVA 712
Query: 658 P-SPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEV-DCGPPEEVKHATLRFNGTR 715
S C +PCVNGGTC F C C+ G+ GR C DC P G
Sbjct: 713 KNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNP------LPCYNGGIC 766
Query: 716 LGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGY 775
+ V + C+ C P ++ P + IDEC+S PC +G +C D + GY
Sbjct: 767 VDGVNWFRCE-------------CAPG--FAGPDCRINIDECQSSPCAYGATCVDEINGY 811
Query: 776 LCLCSTGYEGAHCEL-----ERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEV 830
C C G G C+ R P +G S + CRC G +
Sbjct: 812 RCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSW--VEDCNSCRCLDG----RRDCSK 865
Query: 831 DACDSSPCQHGGRCESGGGAYLCVCPESFFGYHC-ETVSDPCFSSPCGGRGYCLASN-GS 888
C PC G+ E A CP G C E C PC G C A S
Sbjct: 866 VWCGWKPCLLAGQPE----ALSAQCP---LGQRCLEKAPGQCLRPPCEAWGECGAEEPPS 918
Query: 889 HSCTCKVGYTGEDCAK 904
C + G+ +CA+
Sbjct: 919 TPCLPRSGHLDNNCAR 934
Score = 337 bits (863), Expect = 6e-92
Identities = 205/651 (31%), Positives = 271/651 (41%), Gaps = 90/651 (13%)
Query: 297 CSCLSGFTGRRCHLDVNECASQPCQNGGTCTHG--INSFRCQCPAGFGGPTCETAQSPCD 354
C C G+ GR C +EC P C HG + ++C C +GG C+ + C
Sbjct: 262 CRCSYGWQGRFC----DECVPYP-----GCVHGSCVEPWQCNCETNWGGLLCDKDLNYCG 312
Query: 355 TKE-CQHGGQC-QVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCL 412
+ C +GG C E C C GY+G CE C+ +PC NGGSC ++ + C
Sbjct: 313 SHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECH 372
Query: 413 CAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC 472
C + G C D C S PC GGTCVD G+ C CPE ++G C+ V +DC
Sbjct: 373 CPSGWSGPTCALDI----DECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDV-NDC 427
Query: 473 --ECRNGGRCLG-ANTTLCQCPLGFFGLLCEFE---ITAMPCNMNTQCPD---GGYCMEH 523
+C++GG C N C CP GF G CE E + PC+ C D G +C
Sbjct: 428 RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCP 487
Query: 524 GGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKAR--- 580
G +C D + C+ PC NG C + Y C CP F GK+C R
Sbjct: 488 QGFSGPLCEVDVDL-------CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPC 540
Query: 581 -------------------PHLCSSGPCRNGGTC-KEAGGEYHCSCPYRFTGRHCEIGKP 620
P +SG C G C + GG + C C FTG +C
Sbjct: 541 PGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCH-ENI 599
Query: 621 DSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFF 680
D C PC NGGTC + ++C CP G+ G C+ P+ C PC + G C D DF+
Sbjct: 600 DDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 659
Query: 681 CHCQAGYMGRRCQA-EVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSL-SAPSRIRV 738
C C G+ G+ C + E C Y C G + + R
Sbjct: 660 CACDDGWKGKTCHSREFQCDA---------------------YTCSNGGTCYDSGDTFRC 698
Query: 739 CQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAH 798
P G + C PC++GG+C A + C+C G+EG C ++C
Sbjct: 699 ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPL 758
Query: 799 PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPES 858
PC NGG C + + C C GF G C +D C SSPC +G C Y C CP
Sbjct: 759 PCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPG 818
Query: 859 FFGYHCETVSDPCFSSPCGGRGYCLASNGS-----HSCTCKVGYTGEDCAK 904
G C+ V F C RG S +SC C G DC+K
Sbjct: 819 RAGPRCQEVIG--FGRSCWSRGTPFPHGSSWVEDCNSCRCLDG--RRDCSK 865
Score = 273 bits (697), Expect = 1e-72
Identities = 168/547 (30%), Positives = 232/547 (42%), Gaps = 52/547 (9%)
Query: 375 CQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACL 434
C Y A C C P G D GN C+ + + G C+ +A
Sbjct: 198 CDENYYSATCNKF---CRPRNDFFGHYTCDQYGNKACM--DGWMGKECK-------EAVC 245
Query: 435 SAPCH--NGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPL 492
C+ +GG V + C C G+ G C E VP C +G C+ C C
Sbjct: 246 KQGCNLLHGGCTVPGE----CRCSYGWQGRFCDECVPYP-GCVHGS-CV--EPWQCNCET 297
Query: 493 GFFGLLCEFEITAMPCNMNTQCPDGGYCME-HGGSYLCVCHTDHNASH--SLPSPCDSDP 549
+ GLLC+ ++ C + C +GG C+ Y C C ++ + C S+P
Sbjct: 298 NWGGLLCDKDLNY--CGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNP 355
Query: 550 CFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYR 609
C NGGSC + C CP G+ G C C+S PC GGTC + + C CP +
Sbjct: 356 CANGGSCHEVPSGFECHCPSGWSGPTCALDIDE-CASNPCAAGGTCVDQVDGFECICPEQ 414
Query: 610 FTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNG 669
+ G C++ D G C +GGTC + Y+C CP GF GRHCE+ C SPC +G
Sbjct: 415 WVGATCQLDVND--CRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSG 472
Query: 670 GTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYS 729
G CED F CHC G+ G C+ +VD P ++ +N L AC +
Sbjct: 473 GLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYN---LEGDYYCACPDDFG 529
Query: 730 LSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP------------CLHGGSCQDRVAG-YL 776
S R P G C ID C S C G C + G +
Sbjct: 530 GKNCSVPREPCPGGA------CRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 583
Query: 777 CLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSS 836
C+C +G+ G +C D+C PCRNGG+C + A+ C CP+G+ G C+T + C
Sbjct: 584 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 643
Query: 837 PCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVG 896
PC GRC + C C + + G C + C + C G C S + C C G
Sbjct: 644 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPG 703
Query: 897 YTGEDCA 903
+ G CA
Sbjct: 704 WKGSTCA 710
Score = 242 bits (618), Expect = 2e-63
Identities = 126/367 (34%), Positives = 179/367 (48%), Gaps = 54/367 (14%)
Query: 565 CECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCA 624
C C G+ G+ C++ P+ P G+C E + C+C + G C+ +
Sbjct: 262 CRCSYGWQGRFCDECVPY-----PGCVHGSCVEP---WQCNCETNWGGLLCDKDLNYCGS 313
Query: 625 SGPCHNGGTCFHYI-GKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHC 683
PC NGGTC + +Y+C CP G+SGR+CE A C +PC NGG+C + + F CHC
Sbjct: 314 HHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHC 373
Query: 684 QAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHG 743
+G+ G C ++D E GT + V + C +C
Sbjct: 374 PSGWSGPTCALDID-----ECASNPCAAGGTCVDQVDGFEC-------------ICPEQ- 414
Query: 744 VWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNG 803
W L++++CR Q C HGG+C+D V GY C+C G+ G HCELERDEC + PC +G
Sbjct: 415 -WVGATCQLDVNDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSG 472
Query: 804 GSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYH 863
G C +L + C CP GF G CE +VD C+ SPC++G RC + G Y C CP+ F G +
Sbjct: 473 GLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKN 532
Query: 864 CETVSDPC-----------------------FSSPCGGRGYCLAS-NGSHSCTCKVGYTG 899
C +PC S CG G C++ G+ SC C G+TG
Sbjct: 533 CSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTG 592
Query: 900 EDCAKEL 906
C + +
Sbjct: 593 TYCHENI 599
Score = 221 bits (563), Expect = 4e-57
Identities = 150/530 (28%), Positives = 205/530 (38%), Gaps = 147/530 (27%)
Query: 451 YVCE------CPEGFMGLDCRERVPDDCECRNGGRCLGANTTL---CQCPLGFFGLLCEF 501
Y C+ C +G+MG +C+E V C+ G L T+ C+C G+ G C+
Sbjct: 221 YTCDQYGNKACMDGWMGKECKEAV-----CKQGCNLLHGGCTVPGECRCSYGWQGRFCD- 274
Query: 502 EITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDD 561
C+ + G CV GSC +
Sbjct: 275 -----------------ECVPYPG---CV----------------------HGSCV---E 289
Query: 562 SYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAG-GEYHCSCPYRFTGRHCEIGKP 620
+ C C + G C+K + S PC NGGTC A +Y C+CP ++GR+CE +
Sbjct: 290 PWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAE- 348
Query: 621 DSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFF 680
+C S PC NGG+C ++C CP G+SG C + C +PC GGTC D+ F
Sbjct: 349 HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFE 408
Query: 681 CHCQAGYMGRRCQAEV-DCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVC 739
C C ++G CQ +V DC + GT V Y C VC
Sbjct: 409 CICPEQWVGATCQLDVNDC-------RGQCQHGGTCKDLVNGYQC-------------VC 448
Query: 740 QPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP 799
P G + LE DEC S PC GG C+D G+ C C G+ G CE++ D C P
Sbjct: 449 -PRGFGGRHCE-LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSP 506
Query: 800 CRN--------------------------------GGSCRNLPGA--------------- 812
CRN GG+CR + G
Sbjct: 507 CRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASG 566
Query: 813 ---------------YVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPE 857
+ C C +GF G +C +D C PC++GG C A+ C CP
Sbjct: 567 VCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPS 626
Query: 858 SFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELF 907
+ G C+T + C PC RG C C C G+ G+ C F
Sbjct: 627 GWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREF 676
Score = 189 bits (480), Expect = 2e-47
Identities = 115/386 (29%), Positives = 161/386 (41%), Gaps = 35/386 (9%)
Query: 262 VGGCGHTTSVCL----ALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECAS 317
+ GCG + A C G+C+ +++C C SGFTG CH ++++C
Sbjct: 548 IDGCGSDAGPGMPGTAASGVCGPHGRCVSQ---PGGNFSCICDSGFTGTYCHENIDDCLG 604
Query: 318 QPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQA 377
QPC+NGGTC +++FRC CP+G+ G C+T + C C G+C C C
Sbjct: 605 QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDD 664
Query: 378 GYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAP 437
G+ G C C C NGG+C D + C C +KG C + +CL P
Sbjct: 665 GWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKN---SSCLPNP 721
Query: 438 CHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCL-GANTTLCQCPLG 493
C NGGTCV + + C C +G+ G C +DC C NGG C+ G N C+C G
Sbjct: 722 CVNGGTCVGSGASFSCICRDGWEGRTCTHNT-NDCNPLPCYNGGICVDGVNWFRCECAPG 780
Query: 494 FFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNG 553
F G C I ++ C G C++ Y C C C++
Sbjct: 781 FAGPDCRINIDEC---QSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSR 837
Query: 554 GSCDAH-----DDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPY 608
G+ H +D +C C G + C K C PC G + + CP
Sbjct: 838 GTPFPHGSSWVEDCNSCRCLDG--RRDCSKV---WCGWKPCLLAGQPEALSAQ----CP- 887
Query: 609 RFTGRHCEIGKPDSCASGPCHNGGTC 634
G+ C P C PC G C
Sbjct: 888 --LGQRCLEKAPGQCLRPPCEAWGEC 911
Score = 48.1 bits (113), Expect = 6e-05
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 11/62 (17%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
+C NPC NGGTCV + SC C G++G R CT ++ P + GG
Sbjct: 716 SCLPNPCVNGGTCVGSGASFSCICRDGWEG-----------RTCTHNTNDCNPLPCYNGG 764
Query: 1370 VC 1371
+C
Sbjct: 765 IC 766
Score = 47.4 bits (111), Expect = 1e-04
Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 12/64 (18%)
Query: 1312 SENPCQNGGTCVPGA-DAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
S +PC NGGTC+ D + C C G+ GR CE K CT + P GG
Sbjct: 313 SHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE----KAEHACT-------SNPCANGGS 361
Query: 1371 CHHV 1374
CH V
Sbjct: 362 CHEV 365
Score = 45.1 bits (105), Expect = 5e-04
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
+C+ PC NGG CV G + C+C PGF G C + + S PC
Sbjct: 754 DCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPC 798
Score = 42.4 bits (98), Expect = 0.003
Identities = 15/34 (44%), Positives = 21/34 (61%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
+C PC+NGGTC+ DA C C G++G C+
Sbjct: 601 DCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCD 634
Score = 40.0 bits (92), Expect = 0.016
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C+ +PC +GG C AD C C GF G CE+
Sbjct: 464 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV 497
Score = 39.3 bits (90), Expect = 0.027
Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 11/62 (17%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
N CQ+GGTC + + C C GF GR CEL E + P GG
Sbjct: 425 NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDECASSPCHSGG 473
Query: 1370 VC 1371
+C
Sbjct: 474 LC 475
Score = 39.3 bits (90), Expect = 0.027
Identities = 14/33 (42%), Positives = 18/33 (54%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C +PC G TCV + + C C PG G RC+
Sbjct: 793 CQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQ 825
Score = 38.9 bits (89), Expect = 0.035
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C+ NPC NGG+C C C G+ G C L + S PC
Sbjct: 351 CTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPC 394
Score = 38.9 bits (89), Expect = 0.035
Identities = 15/34 (44%), Positives = 18/34 (52%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C+ NPC GGTCV D C C + G C+L
Sbjct: 389 CASNPCAAGGTCVDQVDGFECICPEQWVGATCQL 422
Score = 34.3 bits (77), Expect = 0.87
Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 11/65 (16%)
Query: 1308 PGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWE 1367
P +C +PC + G C + C C G+KG+ C +R F + A+
Sbjct: 637 PNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCH----------SREF-QCDAYTCSN 685
Query: 1368 GGVCH 1372
GG C+
Sbjct: 686 GGTCY 690
Score = 31.2 bits (69), Expect = 7.4
Identities = 11/34 (32%), Positives = 16/34 (47%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C +PC+NG C + C C F G+ C +
Sbjct: 502 CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSV 535
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 341 bits (874), Expect = 3e-93
Identities = 199/651 (30%), Positives = 291/651 (44%), Gaps = 84/651 (12%)
Query: 288 CVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCE 347
C+ + + CS L + C +D +C S C+NG T TH F +C GF G CE
Sbjct: 620 CLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCE 679
Query: 348 TAQSPCDTKECQHGGQCQVENGSAVC--------------VCQAGYTGAACEMDVDDCSP 393
C + C++G C + G+ C +C GY G CE D+DDC
Sbjct: 680 IDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCIL 739
Query: 394 DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVC 453
+ C + +C DL +Y C+C ++G CE + C PC N TC D + Y C
Sbjct: 740 NACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNE----CKMNPCKNNSTCTDLYKSYRC 795
Query: 454 ECPEGFMGLDCRERVPDDCE---CRNGGRCLGANTT---LCQCPLGFFGLLCE-----FE 502
EC G+ G +C E + ++C+ C NGG C + +C CP + G C +
Sbjct: 796 ECTSGWTGQNCSEEI-NECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD 854
Query: 503 ITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSD-------PCFNGGS 555
+ PC N+ C +H C+C + + C+ D C + G
Sbjct: 855 LLHNPCRNNSTCLALVDANQH-----CICREEFEGKN-----CEIDVKDCLFLSCQDYGD 904
Query: 556 CDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHC 615
C+ +++ C C GF G CE + CSS PC+N GTC + + C+C + G C
Sbjct: 905 CEDMVNNFRCICRPGFSGSLCE-IEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC 963
Query: 616 EIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDR 675
E+ + C PC + C + Y C C PG++G +CEI C PC++ G C D
Sbjct: 964 ELDV-NKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDG 1022
Query: 676 DTDFFCHCQAGYMGRRCQAEV-DCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPS 734
+ C C++G+ G C+ DC + + L T L + Y C
Sbjct: 1023 INHYTCDCKSGFFGTHCETNANDC-----LSNPCLHGRCTEL--INEYPCS--------- 1066
Query: 735 RIRVCQPHGVWSEPPQC-LEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERD 793
C G + QC ++I++C S PC++ G CQ G+ C+C GY GA+CE D
Sbjct: 1067 ----CDADGTST---QCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSID 1119
Query: 794 ECRAHP------CRNGGSCRNLPG-AYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCES 846
C A P C NGG C + PG + CRC GF G CE ++ C SSPC HG CE
Sbjct: 1120 NC-AEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCED 1178
Query: 847 GGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 897
Y+C C + G+HCE + C + C C+ + +C C G+
Sbjct: 1179 HINGYVCKCQPGWSGHHCENELE-CIPNSC-VHELCMENEPGSTCLCTPGF 1227
Score = 325 bits (834), Expect = 1e-88
Identities = 200/639 (31%), Positives = 275/639 (43%), Gaps = 65/639 (10%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQC 337
C NG C+ + + Y C + G + + CQ+ C IN RC C
Sbjct: 535 CANGCSCLSE--EDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSC 592
Query: 338 PAGFGGPTCETAQSPC-DTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPC 396
+ G C C G C + + C Y CE+D +DC C
Sbjct: 593 SLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASC 652
Query: 397 LNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECP 456
NG + L G + C FKG +CE D C S PC NG TC+D Y C+C
Sbjct: 653 KNGTTSTHLRGYFFRKCVPGFKGTQCEIDI----DECASHPCKNGATCIDQPGNYFCQCV 708
Query: 457 EGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPD 516
F +D G CL C G+ G+ CE +I C +N C
Sbjct: 709 PPFKVVD-------------GFSCL--------CNPGYVGIRCEQDID--DCILNA-CEH 744
Query: 517 GGYCMEHGGSYLCVCHTDH--NASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGK 574
C + SY CVC +D N + C +PC N +C SY CEC G+ G+
Sbjct: 745 NSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQ 804
Query: 575 HCEKARPHLCSSGPCRNGGTCKEAG--GEYHCSCPYRFTGRHCEIGKPDSC--ASGPCHN 630
+C + + C S PC NGG C E+ G++ C CP +TG+ C + + C PC N
Sbjct: 805 NCSE-EINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCH-QRYNLCDLLHNPCRN 862
Query: 631 GGTCFHYI-GKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMG 689
TC + C C F G++CEI C C + G CED +F C C+ G+ G
Sbjct: 863 NSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSG 922
Query: 690 RRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQP--HGVWSE 747
C+ E++ E K+ NGT + + C+ C+P HG + E
Sbjct: 923 SLCEIEINECSSEPCKN-----NGTCVDLTNRFFCN-------------CEPEYHGPFCE 964
Query: 748 PPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCR 807
L++++C+ PCL +C R GY CLC+ GY G +CE+ DEC + PC + G C
Sbjct: 965 ----LDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCI 1020
Query: 808 NLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETV 867
+ Y C C +GF G HCET + C S+PC HG RC Y C C C+
Sbjct: 1021 DGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIK 1079
Query: 868 SDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
+ C S PC G+C S +C C GYTG C K +
Sbjct: 1080 INDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI 1118
Score = 303 bits (777), Expect = 6e-82
Identities = 187/584 (32%), Positives = 261/584 (44%), Gaps = 56/584 (9%)
Query: 274 ALRPCLNGGKCIDD-----CVTGNP-----SYTCSCLSGFTGRRCHLDVNECASQPCQNG 323
A PC NG CID C P ++C C G+ G RC D+++C C++
Sbjct: 686 ASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHN 745
Query: 324 GTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAA 383
TC S++C C + + G CE + C C++ C S C C +G+TG
Sbjct: 746 STCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQN 805
Query: 384 CEMDVDDCSPDPCLNGGSCVD--LVGNYTCLCAEPFKGLRCETGDHPVPDAC--LSAPCH 439
C ++++C DPC+NGG C + + G + CLC + G C H + C L PC
Sbjct: 806 CSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFC----HQRYNLCDLLHNPCR 861
Query: 440 NGGTC---VDADQGYVCECPEGFMGLDCRERVPD--DCECRNGGRCLG-ANTTLCQCPLG 493
N TC VDA+Q C C E F G +C V D C++ G C N C C G
Sbjct: 862 NNSTCLALVDANQH--CICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPG 919
Query: 494 FFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSL--PSPCDSDPCF 551
F G LCE EI C+ + C + G C++ + C C +++ + C PC
Sbjct: 920 FSGSLCEIEIN--ECS-SEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCL 976
Query: 552 NGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFT 611
+ +C D Y C C G+ G +CE C S PC + G C + Y C C F
Sbjct: 977 DEENCVYRTDGYNCLCAPGYTGINCE-INLDECLSEPCLHDGVCIDGINHYTCDCKSGFF 1035
Query: 612 GRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGT 671
G HCE D C S PC + G C I +Y C C + C+I + C PC+N G
Sbjct: 1036 GTHCETNAND-CLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGF 1093
Query: 672 CEDRDTDFFCHCQAGYMGRRCQAEVD-CGPPEEVKHATLRFNGTRLGAVALYACDRGYSL 730
C+ F C C GY G C+ +D C PE ++ + NG G +
Sbjct: 1094 CQKSAHGFTCICPRGYTGAYCEKSIDNCAEPE--LNSVICLNG-------------GICV 1138
Query: 731 SAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCEL 790
P C+ +S + I+EC S PCLHG C+D + GY+C C G+ G HCE
Sbjct: 1139 DGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCEN 1198
Query: 791 ERDECRAHPCRNGGSCRNLPGAYVCRCPAGF----VGVHCETEV 830
E EC + C + N PG+ C C GF +G+ C E+
Sbjct: 1199 EL-ECIPNSCVHELCMENEPGS-TCLCTPGFMTCSIGLLCGDEI 1240
Score = 263 bits (673), Expect = 7e-70
Identities = 189/741 (25%), Positives = 273/741 (36%), Gaps = 137/741 (18%)
Query: 274 ALRPCLNGGKCIDDCVTGNP-SYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINS 332
+ +PC N G CI+ + +Y C C FTG+ C + +C C +G NS
Sbjct: 218 SFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNS 277
Query: 333 FRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCS 392
F C+C F GP CE + PC + G C + + C G + E DV + S
Sbjct: 278 FICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS 337
Query: 393 PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYV 452
PC NG C+ + + C+C+ F L C++ + +C S P N TC ++ Y
Sbjct: 338 LVPCQNGTDCIKISNDVMCICSPIFTDLLCKS----IQTSCESFPLRNNATCKKCEKDYP 393
Query: 453 CECPEGFMGLDCRERVPDDCE-----CRNGGRCLG------------------------- 482
C C GF +C E+ D C+ C N C
Sbjct: 394 CSCISGFTEKNC-EKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVY 452
Query: 483 -ANTTLCQCPLGFFGLL-----CEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHT--- 533
+ LC C + F G+ +FE + +G C +Y +
Sbjct: 453 LIHQHLCYCGVTFHGICQDKGPAQFEYV---WQLGFAGSEGEKCQGVIDAYFFLAANCTE 509
Query: 534 ---------DHNASHSLPSPCDSDPCFNGGSCDAHDDSY--------------------- 563
D+N+S P + C NG SC + +DS
Sbjct: 510 DATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTD 569
Query: 564 -------------------TCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHC 604
C C + G+ C + + G C +C
Sbjct: 570 DQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNC 629
Query: 605 SCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRS 664
S R+ CEI D C S C NG T H G + C PGF G CEI C
Sbjct: 630 SGLQRYERNICEIDTED-CKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASH 688
Query: 665 PCVNGGTCEDRDTDFFCH--------------CQAGYMGRRCQAEVDCGPPEEVKHATLR 710
PC NG TC D+ ++FC C GY+G RC+ ++D
Sbjct: 689 PCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDID------------- 735
Query: 711 FNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQD 770
L AC+ + C W E +EC+ PC + +C D
Sbjct: 736 -------DCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTD 788
Query: 771 RVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCR--NLPGAYVCRCPAGFVGVHCET 828
Y C C++G+ G +C E +EC + PC NGG C +PG +VC CP + G C
Sbjct: 789 LYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQ 848
Query: 829 EVDACD--SSPCQHGGRCESGGGA-YLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLAS 885
+ CD +PC++ C + A C+C E F G +CE C C G C
Sbjct: 849 RYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDM 908
Query: 886 NGSHSCTCKVGYTGEDCAKEL 906
+ C C+ G++G C E+
Sbjct: 909 VNNFRCICRPGFSGSLCEIEI 929
Score = 219 bits (558), Expect = 1e-56
Identities = 130/406 (32%), Positives = 180/406 (44%), Gaps = 45/406 (11%)
Query: 265 CGHTTSVC-LALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNG 323
C ++C L PC N C+ + + C C F G+ C +DV +C CQ+
Sbjct: 846 CHQRYNLCDLLHNPCRNNSTCL---ALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDY 902
Query: 324 GTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAA 383
G C +N+FRC C GF G CE + C ++ C++ G C C C+ Y G
Sbjct: 903 GDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPF 962
Query: 384 CEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGT 443
CE+DV+ C PCL+ +CV Y CLCA + G+ CE D CLS PC + G
Sbjct: 963 CELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEIN----LDECLSEPCLHDGV 1018
Query: 444 CVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGANTTLCQCPLGFFGLLCE 500
C+D Y C+C GF G C E +DC C +G N C C C+
Sbjct: 1019 CIDGINHYTCDCKSGFFGTHC-ETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCK 1077
Query: 501 FEI---TAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS-------PCDSDPC 550
+I T++PC MN G+C + + C+C + ++ S +S C
Sbjct: 1078 IKINDCTSIPC-MNE-----GFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVIC 1131
Query: 551 FNGGSC-DAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYR 609
NGG C D ++ C C GF G+ CE + CSS PC +G C++ Y C C
Sbjct: 1132 LNGGICVDGPGHTFDCRCLPGFSGQFCE-ININECSSSPCLHGADCEDHINGYVCKCQPG 1190
Query: 610 FTGRHCEIGK---PDSCASGPC---HNGGTCFHYIGKYKCDCPPGF 649
++G HCE P+SC C G TC C PGF
Sbjct: 1191 WSGHHCENELECIPNSCVHELCMENEPGSTCL---------CTPGF 1227
Score = 206 bits (525), Expect = 1e-52
Identities = 118/348 (33%), Positives = 164/348 (47%), Gaps = 24/348 (6%)
Query: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGIN 331
CL L C + G C +D V ++ C C GF+G C +++NEC+S+PC+N GTC N
Sbjct: 894 CLFLS-CQDYGDC-EDMVN---NFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTN 948
Query: 332 SFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDC 391
F C C + GP CE + C C C C+C GYTG CE+++D+C
Sbjct: 949 RFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDEC 1008
Query: 392 SPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGY 451
+PCL+ G C+D + +YTC C F G CET + CLS PC + G C + Y
Sbjct: 1009 LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETN----ANDCLSNPCLH-GRCTELINEY 1063
Query: 452 VCECPEGFMGLDCRERVPD--DCECRNGGRC-LGANTTLCQCPLGFFGLLCEFEI--TAM 506
C C C+ ++ D C N G C A+ C CP G+ G CE I A
Sbjct: 1064 PCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAE 1123
Query: 507 PCNMNTQCPDGGYCME-HGGSYLCVCHTDHNAS--HSLPSPCDSDPCFNGGSCDAHDDSY 563
P + C +GG C++ G ++ C C + + C S PC +G C+ H + Y
Sbjct: 1124 PELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGY 1183
Query: 564 TCECPRGFHGKHCE---KARPHLCSSGPCRN---GGTCKEAGGEYHCS 605
C+C G+ G HCE + P+ C C G TC G CS
Sbjct: 1184 VCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCS 1231
Score = 164 bits (415), Expect = 6e-40
Identities = 148/648 (22%), Positives = 225/648 (34%), Gaps = 143/648 (22%)
Query: 350 QSPCDTKECQHGGQCQVENGSAV--CVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVG 407
Q ++ C G+C E S C CQ ++G C+ ++D CS PC N GSC++
Sbjct: 175 QESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRE 233
Query: 408 N-----YTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGL 462
N Y C+C PF G C + C C +G ++CEC E F G
Sbjct: 234 NWDEQAYECVCHPPFTGKNCS----EIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGP 289
Query: 463 DCRERVPDDCECRNGGRCLGANTTLC---QCPLGFFGLLCEFEITAMPCNMNTQCPDGGY 519
C R + N++ +CP G E +++ C +G
Sbjct: 290 FCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSL---VPCQNGTD 346
Query: 520 CMEHGGSYLCVC---HTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC 576
C++ +C+C TD S+ + C+S P N +C + Y C C GF K+C
Sbjct: 347 CIKISNDVMCICSPIFTD-LLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Query: 577 EKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFH 636
EKA H CK S C N CF+
Sbjct: 406 EKAIDH------------CK--------------------------LLSINCLNEEWCFN 427
Query: 637 YIGKYKCDCPPGFSGRHCEIAPSP--CFRSPCVNG----GTCEDRDTDFFCHCQ----AG 686
IG++K C PG + C + + C G G C+D+ F + AG
Sbjct: 428 IIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAG 487
Query: 687 YMGRRCQAEVDC----------------GPPEEVKHATLRFNGTRLGAVALYACDRGYSL 730
G +CQ +D P + GT+ + C
Sbjct: 488 SEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTK--EICANGCSCLSEE 545
Query: 731 SAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEG----- 785
+ +C W+ + + C H C+D + C CS Y G
Sbjct: 546 DSQEYRYLCFLR--WAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVV 603
Query: 786 --------------------AH--------------CELERDECRAHPCRNGGSCRNLPG 811
+H CE++ ++C++ C+NG + +L G
Sbjct: 604 NVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRG 663
Query: 812 AYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYL--------------CVCPE 857
+ +C GF G CE ++D C S PC++G C G Y C+C
Sbjct: 664 YFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNP 723
Query: 858 SFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKE 905
+ G CE D C + C C + S+ C C + G C +E
Sbjct: 724 GYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQE 771
Score = 94.7 bits (234), Expect = 5e-19
Identities = 63/244 (25%), Positives = 90/244 (36%), Gaps = 20/244 (8%)
Query: 666 CVNGGTC--EDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYA 723
C G C E + CHCQ + G+ CQ E+D + K+ N Y
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYE 241
Query: 724 CDRGYSLSAPSRIRVCQPHGVWSEPPQCLEI-DECRSQPCLHGGSCQDRVAGYLCLCSTG 782
C VC P C EI +C+ C HG ++C C
Sbjct: 242 C-------------VCHPPFTGKN---CSEIIGQCQPHVCFHGNCSNITSNSFICECDEQ 285
Query: 783 YEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGG 842
+ G CE+ C + G C N AY CP G + ET+V PCQ+G
Sbjct: 286 FSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGT 345
Query: 843 RCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
C +C+C F C+++ C S P C + C+C G+T ++C
Sbjct: 346 DCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Query: 903 AKEL 906
K +
Sbjct: 406 EKAI 409
Score = 63.9 bits (154), Expect = 1e-09
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 10/93 (10%)
Query: 754 IDECRSQPCL-----HGGSCQDRVAGYLCLCSTGYEGAHCELERDECRA-----HPCRNG 803
+ +C + PC +GG+C + C C+TG++G+ C C H C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 804 GSCRNLPGAYVCRCPAGFVGVHCETEVDACDSS 836
+C +LP Y C CP G G++CE + D S
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
Score = 62.8 bits (151), Expect = 2e-09
Identities = 32/84 (38%), Positives = 39/84 (46%), Gaps = 4/84 (4%)
Query: 572 HGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNG 631
HGK+ E C+ CRN GTC C CP ++G+ C+ SC + PC NG
Sbjct: 2327 HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA---SCENNPCGNG 2383
Query: 632 GTCFHYIG-KYKCDCPPGFSGRHC 654
TC G C CP G SG C
Sbjct: 2384 ATCVPKSGTDIVCLCPYGRSGPLC 2407
Score = 61.2 bits (147), Expect = 7e-09
Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 7/79 (8%)
Query: 351 SPCDTKECQHGGQCQVENGSAV-CVCQAGYTGAACEMDVDDCSP--DP---CLNGGSCVD 404
SPC +C +GG C +E+G++V C C G+ G+ C V C P DP C G +C+
Sbjct: 2612 SPCSLMKCGNGGTC-IESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCIS 2670
Query: 405 LVGNYTCLCAEPFKGLRCE 423
L YTC C G+ CE
Sbjct: 2671 LPHGYTCFCPLGTTGIYCE 2689
Score = 59.7 bits (143), Expect = 2e-08
Identities = 28/72 (38%), Positives = 40/72 (55%), Gaps = 4/72 (5%)
Query: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTC-KEAGGEYH 603
C C N G+C + +++ CECPR + GK C+ A C + PC NG TC ++G +
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS---CENNPCGNGATCVPKSGTDIV 2395
Query: 604 CSCPYRFTGRHC 615
C CPY +G C
Sbjct: 2396 CLCPYGRSGPLC 2407
Score = 58.2 bits (139), Expect = 6e-08
Identities = 33/93 (35%), Positives = 42/93 (45%), Gaps = 11/93 (11%)
Query: 623 CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRD-TDFFC 681
CA C N GTC C+CP +SG+ C+ A C +PC NG TC + TD C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTDIVC 2396
Query: 682 HCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGT 714
C G G C ++ P RF+GT
Sbjct: 2397 LCPYGRSGPLCTDAINITQP--------RFSGT 2421
Score = 57.4 bits (137), Expect = 1e-07
Identities = 33/88 (37%), Positives = 40/88 (45%), Gaps = 7/88 (7%)
Query: 584 CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHC----EIGKPDSCASGPCHNGGTCFHYIG 639
CS C NGGTC E+G +C+C + G C P+ C G TC
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 640 KYKCDCPPGFSGRHCEIAPS---PCFRS 664
Y C CP G +G +CE A S P FRS
Sbjct: 2674 GYTCFCPLGTTGIYCEQALSISDPSFRS 2701
Score = 55.8 bits (133), Expect = 3e-07
Identities = 34/120 (28%), Positives = 49/120 (40%), Gaps = 8/120 (6%)
Query: 800 CRNGGSCRNLPGA--YVCRCPAGFVGVHCETEVDACDSSPCQHGGRCES-----GGGAYL 852
C G C + + Y C C F G +C+ E+DAC PC++ G C + AY
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYE 241
Query: 853 CVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTAL 912
CVC F G +C + C C ++ S C C ++G C P +L
Sbjct: 242 CVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL 301
Score = 55.5 bits (132), Expect = 4e-07
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Query: 308 CHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVE 367
CH V CA C+N GTC + C+CP + G C+ A C+ C +G C +
Sbjct: 2334 CH--VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPK 2389
Query: 368 NGS-AVCVCQAGYTGAACEMDVDDCSP 393
+G+ VC+C G +G C ++ P
Sbjct: 2390 SGTDIVCLCPYGRSGPLCTDAINITQP 2416
Score = 55.1 bits (131), Expect = 5e-07
Identities = 29/92 (31%), Positives = 35/92 (38%), Gaps = 7/92 (7%)
Query: 307 RCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTK-----ECQHG 361
+CH + C+ C NGGTC S C C G+ G C S CD + C G
Sbjct: 2608 QCH--ASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 362 GQCQVENGSAVCVCQAGYTGAACEMDVDDCSP 393
C C C G TG CE + P
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDP 2697
Score = 53.9 bits (128), Expect = 1e-06
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 505 AMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDP-------CFNGGSCD 557
A PC++ +C +GG C+E G S C C T S + DP C G +C
Sbjct: 2611 ASPCSL-MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCI 2669
Query: 558 AHDDSYTCECPRGFHGKHCEKA 579
+ YTC CP G G +CE+A
Sbjct: 2670 SLPHGYTCFCPLGTTGIYCEQA 2691
Score = 53.1 bits (126), Expect = 2e-06
Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 391 CSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRC-ETGDHPVPDACLSAPCHNGGTCVDADQ 449
CS C NGG+C++ + C C +KG C ET P+ C G TC+
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 450 GYVCECPEGFMGLDCRE 466
GY C CP G G+ C +
Sbjct: 2674 GYTCFCPLGTTGIYCEQ 2690
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 14/83 (16%)
Query: 543 SPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC---------EKARPHLCSSGPCRNGG 593
SPC C NGG+C S C C G+ G C E PH CS G
Sbjct: 2612 SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS-----RGA 2666
Query: 594 TCKEAGGEYHCSCPYRFTGRHCE 616
TC Y C CP TG +CE
Sbjct: 2667 TCISLPHGYTCFCPLGTTGIYCE 2689
Score = 52.0 bits (123), Expect = 4e-06
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 433 CLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTT--LCQC 490
C C N GTC+ ++ CECP + G C+ ++ C NG C+ + T +C C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLC 2398
Query: 491 PLGFFGLLC 499
P G G LC
Sbjct: 2399 PYGRSGPLC 2407
Score = 50.8 bits (120), Expect = 9e-06
Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 311 DVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENG- 369
D C C+NGG CT +F C+C + G TC + S C C H C +
Sbjct: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSF 2933
Query: 370 SAVCVCQAGYTGAACE 385
S C+C G+ G CE
Sbjct: 2934 SYSCLCTLGWVGRYCE 2949
Score = 50.1 bits (118), Expect = 2e-05
Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 12/98 (12%)
Query: 262 VGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQ--- 318
VG C S C +L C NGG CI+ S C+C +G+ G C V+ C +
Sbjct: 2606 VGQCH--ASPC-SLMKCGNGGTCIES----GTSVYCNCTTGWKGSFCTETVSTCDPEHDP 2658
Query: 319 --PCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCD 354
C G TC + + C CP G G CE A S D
Sbjct: 2659 PHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISD 2696
Score = 50.1 bits (118), Expect = 2e-05
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 10/77 (12%)
Query: 433 CLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE--------CRNGGRCLG-A 483
C C NGGTC+++ C C G+ G C E V C+ C G C+
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETV-STCDPEHDPPHHCSRGATCISLP 2672
Query: 484 NTTLCQCPLGFFGLLCE 500
+ C CPLG G+ CE
Sbjct: 2673 HGYTCFCPLGTTGIYCE 2689
Score = 48.9 bits (115), Expect = 3e-05
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 7/73 (9%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCT-HGINSFRCQ 336
C N G CI D N + C C ++G+ C C + PC NG TC C
Sbjct: 2344 CRNNGTCISD----NENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTDIVCL 2397
Query: 337 CPAGFGGPTCETA 349
CP G GP C A
Sbjct: 2398 CPYGRSGPLCTDA 2410
Score = 48.1 bits (113), Expect = 6e-05
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRC-ESGGGAYLC 853
C H CRN G+C + C CP + G C + +C+++PC +G C G +C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVC 2396
Query: 854 VCPESFFGYHCE---TVSDPCFS 873
+CP G C ++ P FS
Sbjct: 2397 LCPYGRSGPLCTDAINITQPRFS 2419
Score = 47.8 bits (112), Expect = 8e-05
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 622 SCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTC-EDRDTDFF 680
+C C NGG C + C C P ++G C + S C + C++ C D+ +
Sbjct: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYS 2936
Query: 681 CHCQAGYMGRRCQ 693
C C G++GR C+
Sbjct: 2937 CLCTLGWVGRYCE 2949
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 7/105 (6%)
Query: 365 QVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCET 424
QV N + +A + V C+ C N G+C+ N C C + G C+
Sbjct: 2313 QVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF 2372
Query: 425 GDHPVPDACLSAPCHNGGTCV-DADQGYVCECPEGFMGLDCRERV 468
+C + PC NG TCV + VC CP G G C + +
Sbjct: 2373 A------SCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAI 2411
Score = 46.6 bits (109), Expect = 2e-04
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Query: 832 ACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNG-SHS 890
AC + C++GG C G + C C + G C S C ++ C + C+ S+S
Sbjct: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ-SVSCLNNLCLHQSLCIPDQSFSYS 2936
Query: 891 CTCKVGYTGEDCAKELFPPTA 911
C C +G+ G C + TA
Sbjct: 2937 CLCTLGWVGRYCENKTSFSTA 2957
Score = 46.2 bits (108), Expect = 2e-04
Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 353 CDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCV-DLVGNYTC 411
C C++GG+C V + C C + G C V C + CL+ C+ D +Y+C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 412 LCAEPFKGLRCE 423
LC + G CE
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 45.8 bits (107), Expect = 3e-04
Identities = 28/88 (31%), Positives = 37/88 (42%), Gaps = 13/88 (14%)
Query: 659 SPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD-CGPPEEVKHATLRFNG---- 713
SPC C NGGTC + T +C+C G+ G C V C P + H R
Sbjct: 2612 SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
Query: 714 -------TRLGAVALYACDRGYSLSAPS 734
LG +Y C++ S+S PS
Sbjct: 2672 PHGYTCFCPLGTTGIY-CEQALSISDPS 2698
Score = 45.4 bits (106), Expect = 4e-04
Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query: 584 CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCF-HYIGKYK 642
C CRNGG C G + C C + G C + SC + C + C Y
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC--NQSVSCLNNLCLHQSLCIPDQSFSYS 2936
Query: 643 CDCPPGFSGRHCE 655
C C G+ GR+CE
Sbjct: 2937 CLCTLGWVGRYCE 2949
Score = 45.1 bits (105), Expect = 5e-04
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 6/110 (5%)
Query: 757 CRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGA-YVC 815
C C + G+C C C Y G C+ C +PC NG +C G VC
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTDIVC 2396
Query: 816 RCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCE 865
CP G G C DA + + + G G ++L S +H E
Sbjct: 2397 LCPYGRSGPLC---TDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYE 2443
Score = 44.7 bits (104), Expect = 6e-04
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRC-ESGGGAYLC 853
C + CRNGG C + CRC + G C V +C ++ C H C +Y C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 854 VCPESFFGYHCE 865
+C + G +CE
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 44.3 bits (103), Expect = 8e-04
Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 5/44 (11%)
Query: 617 IGKPDSCASGPCHNGGTCFHY-----IGKYKCDCPPGFSGRHCE 655
+ P C CHNGGTC I ++CDCP F+GR CE
Sbjct: 2097 VAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 10/87 (11%)
Query: 830 VDACDSSPCQ-----HGGRCESGGGAYLCVCPESFFGYHC-ETVS--DPCFSSP--CGGR 879
V C +SPC +GG C G + C C + G C ETVS DP P C
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 880 GYCLASNGSHSCTCKVGYTGEDCAKEL 906
C++ ++C C +G TG C + L
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCEQAL 2692
Score = 43.5 bits (101), Expect = 0.001
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTC-KEAGGEYH 603
C + C NGG C + +++C C + G C ++ C + C + C + Y
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS--CLNNLCLHQSLCIPDQSFSYS 2936
Query: 604 CSCPYRFTGRHCE 616
C C + GR+CE
Sbjct: 2937 CLCTLGWVGRYCE 2949
Score = 42.7 bits (99), Expect = 0.002
Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
Query: 533 TDHNASHSLPSPCDSDPCFNGGSCDA-----HDDSYTCECPRGFHGKHCEK 578
T + S + PS C D C NGG+C A S+ C+CP F G+ CEK
Sbjct: 2091 TSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK 2141
Score = 42.4 bits (98), Expect = 0.003
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 8/60 (13%)
Query: 579 ARPHLCSSGPCRNGGTCKE---AGG--EYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGT 633
A P +C C NGGTC + G + C CP FTGR CE D+ P NG +
Sbjct: 2098 AAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE---KDAGLFFPSFNGNS 2154
Score = 42.4 bits (98), Expect = 0.003
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
Query: 1294 LQLPEHGSK---DIGNVPGN-CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV 1349
LQL E G+K ++G+ G C N C+NGG C SC C P + G C + +
Sbjct: 2858 LQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCL 2917
Query: 1350 SRPC 1353
+ C
Sbjct: 2918 NNLC 2921
Score = 42.4 bits (98), Expect = 0.003
Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 14/88 (15%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
CG+ T C NGG +C +++C CL + G C+ V+ C + C +
Sbjct: 2879 CGYNT--------CRNGG----ECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQS 2925
Query: 325 TCTHGIN-SFRCQCPAGFGGPTCETAQS 351
C + S+ C C G+ G CE S
Sbjct: 2926 LCIPDQSFSYSCLCTLGWVGRYCENKTS 2953
Score = 42.0 bits (97), Expect = 0.004
Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL-ACIKVSRPC 1353
C PC + G C+ G + ++CDC GF G CE A +S PC
Sbjct: 1008 CLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPC 1051
Score = 42.0 bits (97), Expect = 0.004
Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 7/60 (11%)
Query: 474 CRNGGRCLGANTTL-CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGS-YLCVC 531
CRN G C+ N L C+CP + G LC+F C N C +G C+ G+ +C+C
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQF----ASCE-NNPCGNGATCVPKSGTDIVCLC 2398
Score = 41.6 bits (96), Expect = 0.005
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 11/62 (17%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
C NPC+N TC ++ C+C G+ G+ C + +E + P GG+
Sbjct: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNC-----------SEEINECDSDPCMNGGL 823
Query: 1371 CH 1372
CH
Sbjct: 824 CH 825
Score = 41.6 bits (96), Expect = 0.005
Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVS-RPC 1353
CS PC+N GTCV + C+C P + G CEL K PC
Sbjct: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPC 975
Score = 40.4 bits (93), Expect = 0.012
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 14/47 (29%)
Query: 1311 CSENPCQNGGTCV--PG------------ADAHSCDCGPGFKGRRCE 1343
C+ +PC+NG TC+ PG D SC C PG+ G RCE
Sbjct: 685 CASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCE 731
Score = 39.7 bits (91), Expect = 0.021
Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 5/38 (13%)
Query: 315 CASQPCQNGGTC-----THGINSFRCQCPAGFGGPTCE 347
C C NGGTC + GI SF+C CP F G CE
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
Score = 39.7 bits (91), Expect = 0.021
Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 8/103 (7%)
Query: 368 NGSAVCVCQAGYTGAACEMDVDD--CSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETG 425
N + + + G G + D D C + C NGG C ++C C + G C
Sbjct: 2854 NNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQS 2913
Query: 426 DHPVPDACLSAPCHNGGTCV-DADQGYVCECPEGFMGLDCRER 467
+CL+ C + C+ D Y C C G++G C +
Sbjct: 2914 -----VSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENK 2951
Score = 39.3 bits (90), Expect = 0.027
Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC--ELACI 1347
CS +PC +G C + + C C PG+ G C EL CI
Sbjct: 1165 CSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECI 1203
Score = 39.3 bits (90), Expect = 0.027
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 508 CNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS-PCDSDPCFNGGSCDAHDD-SYTC 565
C NT C +GG C +G ++ C C D + S C ++ C + C SY+C
Sbjct: 2879 CGYNT-CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 566 ECPRGFHGKHCE 577
C G+ G++CE
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 38.5 bits (88), Expect = 0.046
Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 5/48 (10%)
Query: 1300 GSKDIGNVPGNCSENPCQ-----NGGTCVPGADAHSCDCGPGFKGRRC 1342
G + G G C +PC NGGTC+ + C+C G+KG C
Sbjct: 2598 GHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFC 2645
Score = 38.1 bits (87), Expect = 0.060
Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C +PC + CV D ++C C PG+ G CE+ + +S PC
Sbjct: 970 CKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPC 1013
Score = 37.7 bits (86), Expect = 0.079
Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
Query: 514 CPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSC-DAHDDSYTCECPRGFH 572
C + G C+ + C C ++ + C+++PC NG +C C CP G
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS 2403
Query: 573 GKHCEKA 579
G C A
Sbjct: 2404 GPLCTDA 2410
Score = 37.0 bits (84), Expect = 0.13
Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 6/62 (9%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
+C+ PC N G C A +C C G+ G CE + + P E + GG
Sbjct: 1082 DCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEP------ELNSVICLNGG 1135
Query: 1370 VC 1371
+C
Sbjct: 1136 IC 1137
Score = 37.0 bits (84), Expect = 0.13
Identities = 32/104 (30%), Positives = 42/104 (40%), Gaps = 18/104 (17%)
Query: 1310 NCSENP-----CQNGGTCVPG-ADAHSCDCGPGFKGRRCELACIKV-SRPCTRLFS---- 1358
NC+E C NGG CV G C C PGF G+ CE+ + S PC
Sbjct: 1120 NCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDH 1179
Query: 1359 ----ETKAFPVWEGGVCHHVYKRVYR--VHQDICFKESCESTSL 1396
K P W G C + + + VH ++C + ST L
Sbjct: 1180 INGYVCKCQPGWSGHHCENELECIPNSCVH-ELCMENEPGSTCL 1222
Score = 36.6 bits (83), Expect = 0.18
Identities = 25/56 (44%), Positives = 29/56 (51%), Gaps = 7/56 (12%)
Query: 1310 NCSENPCQNGGTCVP--GADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAF 1363
+C NPC NG TCVP G D C C G G C A I +++P FS T AF
Sbjct: 2374 SCENNPCGNGATCVPKSGTDI-VCLCPYGRSGPLCTDA-INITQP---RFSGTDAF 2424
Score = 36.6 bits (83), Expect = 0.18
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 757 CRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPG---AY 813
C C +GG C + C C + G C + C + C + C +P +Y
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSCLNNLCLHQSLC--IPDQSFSY 2935
Query: 814 VCRCPAGFVGVHCETE 829
C C G+VG +CE +
Sbjct: 2936 SCLCTLGWVGRYCENK 2951
Score = 36.2 bits (82), Expect = 0.23
Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 5/41 (12%)
Query: 1308 PGNCSENPCQNGGTC-----VPGADAHSCDCGPGFKGRRCE 1343
P C ++ C NGGTC G + CDC F GR CE
Sbjct: 2100 PSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
Score = 35.4 bits (80), Expect = 0.39
Identities = 14/38 (36%), Positives = 16/38 (42%)
Query: 661 CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDC 698
C + C NGG C T F C C + G C V C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSC 2916
Score = 35.0 bits (79), Expect = 0.51
Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 5/37 (13%)
Query: 1311 CSENPCQNGGTCVPGAD-----AHSCDCGPGFKGRRC 1342
CS PC+N G+C+ + A+ C C P F G+ C
Sbjct: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNC 253
Score = 35.0 bits (79), Expect = 0.51
Identities = 18/75 (24%), Positives = 32/75 (42%), Gaps = 11/75 (14%)
Query: 1297 PEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRL 1356
P K+ + G C + C +G +++ C+C F G CE++ ++PC L
Sbjct: 246 PPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS----AKPCVSL 301
Query: 1357 FSETKAFPVWEGGVC 1371
W+ G+C
Sbjct: 302 L-------FWKRGIC 309
Score = 35.0 bits (79), Expect = 0.51
Identities = 14/32 (43%), Positives = 20/32 (62%), Gaps = 1/32 (3%)
Query: 1314 NPCQNGGTCVPGADAHS-CDCGPGFKGRRCEL 1344
NPC+N TC+ DA+ C C F+G+ CE+
Sbjct: 858 NPCRNNSTCLALVDANQHCICREEFEGKNCEI 889
Score = 34.7 bits (78), Expect = 0.67
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 5/42 (11%)
Query: 430 PDACLSAPCHNGGTC--VDADQGYV---CECPEGFMGLDCRE 466
P C CHNGGTC + G V C+CP F G C +
Sbjct: 2100 PSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK 2141
Score = 34.7 bits (78), Expect = 0.67
Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
C+ + C+N GTC+ + C+C + G+ C+ A + + PC
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCE-NNPC 2380
Score = 34.7 bits (78), Expect = 0.67
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 13/77 (16%)
Query: 432 ACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTL---- 487
AC C NGG C + C C + G C + V C N CL + +
Sbjct: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV----SCLN-NLCLHQSLCIPDQS 2932
Query: 488 ----CQCPLGFFGLLCE 500
C C LG+ G CE
Sbjct: 2933 FSYSCLCTLGWVGRYCE 2949
Score = 34.7 bits (78), Expect = 0.67
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 751 CLEIDECRSQPCLHGGSC-QDRVAGYLCLCSTGYEGAHCE 789
C + C + CLH C D+ Y CLC+ G+ G +CE
Sbjct: 2910 CNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 33.1 bits (74), Expect = 1.9
Identities = 23/94 (24%), Positives = 35/94 (37%), Gaps = 14/94 (14%)
Query: 1306 NVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELA----------CIKVSRPCTR 1355
++ +C P +N TC + C C GF + CE A C+ C
Sbjct: 369 SIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLN-EEWCFN 427
Query: 1356 LFSETK--AFPVWEGGVCHHVYKRVYRVHQDICF 1387
+ K P C + K VY +HQ +C+
Sbjct: 428 IIGRFKYVCIPGCTKNPCWFL-KNVYLIHQHLCY 460
Score = 32.7 bits (73), Expect = 2.5
Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 5/44 (11%)
Query: 657 APSPCFRSPCVNGGTC-----EDRDTDFFCHCQAGYMGRRCQAE 695
APS C + C NGGTC F C C + GR C+ +
Sbjct: 2099 APSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 32.3 bits (72), Expect = 3.3
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 1/45 (2%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
+C CQ+ G C + C C PGF G CE+ + S PC
Sbjct: 893 DCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPC 937
Score = 31.2 bits (69), Expect = 7.4
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 1/45 (2%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
+C C+NG T C PGFKG +CE+ + S PC
Sbjct: 646 DCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPC 690
Score = 30.8 bits (68), Expect = 9.6
Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 7/62 (11%)
Query: 349 AQSPCDTKECQHGGQCQ---VENG--SAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCV 403
A S C C +GG C + +G S C C +TG CE D P NG S +
Sbjct: 2099 APSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPS--FNGNSYL 2156
Query: 404 DL 405
+L
Sbjct: 2157 EL 2158
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 280 bits (716), Expect = 7e-75
Identities = 164/508 (32%), Positives = 228/508 (44%), Gaps = 99/508 (19%)
Query: 433 CLSAPCHNGGTCVDADQGYVCECPEGFMGLD--CRERVPDDC---ECRNGGRCL---GAN 484
CLS C N TC D + C C + LD C + + D C C+ C+ G
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDC-DNMKDPCFSNPCQGSATCVNTPGER 92
Query: 485 TTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSP 544
+ LC+CP G+ G +C E T C N+ +HGG +CH
Sbjct: 93 SFLCKCPPGYSGTIC--ETTIGSCGKNS--------CQHGG----ICH------------ 126
Query: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHC 604
DP + C CP G+ G+ CE C+S PC+NG C++ Y C
Sbjct: 127 --QDPIYP-----------VCICPAGYAGRFCEIDHDE-CASSPCQNGAVCQDGIDGYSC 172
Query: 605 SCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRS 664
C + GRHC++ + D CAS PC N TC + IG+Y C CP +SG +CE+ C+
Sbjct: 173 FCVPGYQGRHCDL-EVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQ 231
Query: 665 PCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYAC 724
PC+NG TC+D +FC C G++G C+ D + H L +G Y+C
Sbjct: 232 PCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENR-----YSC 286
Query: 725 DRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE 784
+ C G + L + C S+PC + +C+D V Y C C GY
Sbjct: 287 N-------------CTGSGFTGTHCETL-MPLCWSKPCHNNATCEDSVDNYTCHCWPGYT 332
Query: 785 GAHCELERDECRAHPCRNGGSCRNLPG--------------------AYVCRCPAGFVGV 824
GA CE++ +EC ++PC++ G C L YVC C GF G+
Sbjct: 333 GAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGI 392
Query: 825 HCETEVDACDSSPCQHGGRCESGGGAYLCVCP-----ESFFGYH-CETVSDPCFSSPCGG 878
HCE +V+ C S+PCQ+GG CE+ G Y C CP +F+G C + C C
Sbjct: 393 HCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLN 452
Query: 879 RGYCLA--SNGSH--SCTCKVGYTGEDC 902
G C+ +G H SC C GYTG C
Sbjct: 453 NGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 280 bits (715), Expect = 9e-75
Identities = 161/471 (34%), Positives = 210/471 (44%), Gaps = 58/471 (12%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C + CL+ C N C D + + +CS + + C + C S PCQ
Sbjct: 27 CNKNNTRCLS-NSCQNNSTCKD--FSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSA 83
Query: 325 TC--THGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGA 382
TC T G SF C+CP G+ G CET C CQHGG C + VC+C AGY G
Sbjct: 84 TCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGR 143
Query: 383 ACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG 442
CE+D D+C+ PC NG C D + Y+C C ++G C+ D C S PC N
Sbjct: 144 FCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDL----EVDECASDPCKNEA 199
Query: 443 TCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGA-NTTLCQCPLGFFGLL 498
TC++ Y C CP + G++C + D+C C NG C A C C GF G
Sbjct: 200 TCLNEIGRYTCICPHNYSGVNCELEI-DECWSQPCLNGATCQDALGAYFCDCAPGFLGDH 258
Query: 499 CEF---EITAMPCNMNTQCPDGGYCMEHGGSYLCVC-HTDHNASH--SLPSPCDSDPCFN 552
CE E + P C GG C++ Y C C + +H +L C S PC N
Sbjct: 259 CELNTDECASQP------CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHN 312
Query: 553 GGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE----------- 601
+C+ D+YTC C G+ G CE + C+S PC++ G C E E
Sbjct: 313 NATCEDSVDNYTCHCWPGYTGAQCE-IDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 371
Query: 602 ---------YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCP------ 646
Y C C FTG HCE + C+S PC NGGTC + G Y C CP
Sbjct: 372 SFSYHEASGYVCICQPGFTGIHCE-EDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSR 430
Query: 647 PGFSGRHCEIAPSPCFRSPCVNGGTC----EDRDTDFFCHCQAGYMGRRCQ 693
+ GR C C C+N GTC +D F C C +GY G C+
Sbjct: 431 TFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 243 bits (619), Expect = 1e-63
Identities = 138/430 (32%), Positives = 188/430 (43%), Gaps = 61/430 (14%)
Query: 510 MNTQCPDGGYCMEHGGSYLCVCHTDHNA----SHSLPSPCDSDPCFNGGSC--DAHDDSY 563
++ C + C + C C N ++ PC S+PC +C + S+
Sbjct: 35 LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94
Query: 564 TCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSC 623
C+CP G+ G CE C C++GG C + C CP + GR CEI D C
Sbjct: 95 LCKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDH-DEC 152
Query: 624 ASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHC 683
AS PC NG C I Y C C PG+ GRHC++ C PC N TC + + C C
Sbjct: 153 ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCIC 212
Query: 684 QAGYMGRRCQAEVD-CGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPH 742
Y G C+ E+D C + AT + A+ Y CD C P
Sbjct: 213 PHNYSGVNCELEIDECWSQPCLNGATCQ------DALGAYFCD-------------CAP- 252
Query: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCS-TGYEGAHCELERDECRAHPCR 801
G + + L DEC SQPCLHGG C D Y C C+ +G+ G HCE C + PC
Sbjct: 253 GFLGDHCE-LNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCH 311
Query: 802 NGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRC----------------- 844
N +C + Y C C G+ G CE +++ C+S+PCQ G C
Sbjct: 312 NNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 371
Query: 845 -----ESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTC------ 893
E+ G Y+C+C F G HCE + C S+PC G C G+++C C
Sbjct: 372 SFSYHEASG--YVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLS 429
Query: 894 KVGYTGEDCA 903
+ Y G DC+
Sbjct: 430 RTFYGGRDCS 439
Score = 234 bits (596), Expect = 6e-61
Identities = 133/389 (34%), Positives = 174/389 (44%), Gaps = 51/389 (13%)
Query: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHG--KHCEKARPHLCSSGPCRNGGTCKEAGGE- 601
C S+ C N +C C C + K C+ + C S PC+ TC GE
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPGER 92
Query: 602 -YHCSCPYRFTGRHCE--IGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAP 658
+ C CP ++G CE IG SC C +GG C C CP G++GR CEI
Sbjct: 93 SFLCKCPPGYSGTICETTIG---SCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDH 149
Query: 659 SPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGA 718
C SPC NG C+D + C C GY GR C EVD + K+ T L
Sbjct: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKN-----EATCLNE 204
Query: 719 VALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCL 778
+ Y C +C PH +S LEIDEC SQPCL+G +CQD + Y C
Sbjct: 205 IGRYTC-------------IC-PHN-YSGVNCELEIDECWSQPCLNGATCQDALGAYFCD 249
Query: 779 CSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCP-AGFVGVHCETEVDACDSSP 837
C+ G+ G HCEL DEC + PC +GG C + Y C C +GF G HCET + C S P
Sbjct: 250 CAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKP 309
Query: 838 CQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGS--------- 888
C + CE Y C C + G CE + C S+PC G C+ +
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGL 369
Query: 889 -----------HSCTCKVGYTGEDCAKEL 906
+ C C+ G+TG C +++
Sbjct: 370 PSSFSYHEASGYVCICQPGFTGIHCEEDV 398
Score = 233 bits (593), Expect = 1e-60
Identities = 135/411 (32%), Positives = 180/411 (43%), Gaps = 44/411 (10%)
Query: 241 TTTNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSY-TCSC 299
+ T V PG +F G TT C +GG C D P Y C C
Sbjct: 82 SATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQD-----PIYPVCIC 136
Query: 300 LSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQ 359
+G+ GR C +D +ECAS PCQNG C GI+ + C C G+ G C+ C + C+
Sbjct: 137 PAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 360 HGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKG 419
+ C E G C+C Y+G CE+++D+C PCLNG +C D +G Y C CA F G
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 420 LRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECP-EGFMGLDCRERVP--DDCECRN 476
CE D C S PC +GG CVD + Y C C GF G C +P C N
Sbjct: 257 DHCELN----TDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHN 312
Query: 477 GGRCL-GANTTLCQCPLGFFGLLCEF---EITAMPCNMNTQCPD--------------GG 518
C + C C G+ G CE E + PC N +C +
Sbjct: 313 NATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSS 372
Query: 519 YCMEHGGSYLCVCHTDHNASHSLP--SPCDSDPCFNGGSCDAHDDSYTCECP-----RGF 571
+ Y+C+C H + C S+PC NGG+C+ +YTC CP R F
Sbjct: 373 FSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTF 432
Query: 572 H-GKHCEKARPHLCSSGPCRNGGTC----KEAGGEYHCSCPYRFTGRHCEI 617
+ G+ C C+ C N GTC ++ + C CP +TG CEI
Sbjct: 433 YGGRDCSDILLG-CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 211 bits (536), Expect = 5e-54
Identities = 145/510 (28%), Positives = 192/510 (37%), Gaps = 119/510 (23%)
Query: 346 CETAQSPCDTKECQHGGQCQVENGSAVCVCQ--AGYTGAACEMDVDDCSPDPCLNGGSCV 403
C + C + CQ+ C+ + C C A C+ D C +PC +CV
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 404 DLVG--NYTCLCAEPFKGLRCET-------------------GDHPV------------- 429
+ G ++ C C + G CET +PV
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 430 --PDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLG-A 483
D C S+PC NG C D GY C C G+ G C V D+C C+N CL
Sbjct: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNEI 205
Query: 484 NTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS--L 541
C CP + G+ CE EI + C +G C + G+Y C C H
Sbjct: 206 GRYTCICPHNYSGVNCELEIDEC---WSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN 262
Query: 542 PSPCDSDPCFNGGSCDAHDDSYTCECP-RGFHGKHCEKARPHLCSSGPCRNGGTCKEAGG 600
C S PC +GG C ++ Y+C C GF G HCE P LC S PC N TC+++
Sbjct: 263 TDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMP-LCWSKPCHNNATCEDSVD 321
Query: 601 EYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTC--------------------FHYIGK 640
Y C C +TG CEI + C S PC + G C +H
Sbjct: 322 NYTCHCWPGYTGAQCEIDL-NECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 641 YKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGP 700
Y C C PGF+G HCE + C +PC NGGTCE+ ++ CHC + R DC
Sbjct: 381 YVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDC-- 438
Query: 701 PEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQ 760
+ LG + G C PH
Sbjct: 439 -----------SDILLGCTHQQCLNNG----------TCIPH------------------ 459
Query: 761 PCLHGGSCQDRVAGYLCLCSTGYEGAHCEL 790
QD G+ CLC +GY G+ CE+
Sbjct: 460 -------FQDGQHGFSCLCPSGYTGSLCEI 482
Score = 138 bits (347), Expect = 4e-32
Identities = 70/201 (34%), Positives = 94/201 (46%), Gaps = 9/201 (4%)
Query: 310 LDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENG 369
L +N C S PC +GG C +S+ C CP G+ G CE C + C HG C
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVA 1196
Query: 370 SAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHP- 428
+ C C+ GYTG CE+D+D+C C NG +C+ Y+CLC F G C P
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 429 --VPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLG- 482
+ + C+NGG C + C C GF G C + + D+C C NGG C
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI-DECASDPCVNGGLCQDL 1315
Query: 483 ANTTLCQCPLGFFGLLCEFEI 503
N C C + F G CE ++
Sbjct: 1316 LNKFQCLCDVAFAGERCEVDL 1336
Score = 137 bits (346), Expect = 6e-32
Identities = 64/165 (38%), Positives = 88/165 (53%), Gaps = 12/165 (7%)
Query: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLP 810
CL+++ C S PCLHGG+C+D + Y C C G+ G HCEL DEC ++PC + G+C +
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRV 1195
Query: 811 GAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDP 870
AY C C G+ GV+CE ++D C S C +G C S Y C+C +F G C P
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 871 CFSSPCGGR---------GYCLASNGSHSCTCKVGYTGEDCAKEL 906
S+ CG G C C C+ G+TGE C K++
Sbjct: 1256 --STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI 1298
Score = 137 bits (345), Expect = 7e-32
Identities = 69/214 (32%), Positives = 100/214 (46%), Gaps = 23/214 (10%)
Query: 582 HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKY 641
++C+S PC +GG C++ YHCSCP ++G+HCE+ D C S PC + G C + Y
Sbjct: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL-NIDECFSNPCIH-GNCSDRVAAY 1198
Query: 642 KCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQ----AEVD 697
C C PG++G +CE+ C C NG TC + C C + G+ C+
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
Query: 698 CGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDEC 757
CG + N T C G++ G W E +IDEC
Sbjct: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT-------------GEWCEK----DIDEC 1301
Query: 758 RSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE 791
S PC++GG CQD + + CLC + G CE++
Sbjct: 1302 ASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335
Score = 132 bits (332), Expect = 2e-30
Identities = 66/210 (31%), Positives = 98/210 (46%), Gaps = 18/210 (8%)
Query: 623 CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCH 682
C S PC +GG C Y C CP G+SG+HCE+ CF +PC++G C DR + C
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCT 1201
Query: 683 CQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRI--RVCQ 740
C+ GY G C+ ++D + + + T GYS + C+
Sbjct: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHTN-----------GYSCLCFGNFTGKFCR 1250
Query: 741 PHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPC 800
S P + +E + C +GG+C + C+C G+ G CE + DEC + PC
Sbjct: 1251 Q----SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPC 1306
Query: 801 RNGGSCRNLPGAYVCRCPAGFVGVHCETEV 830
NGG C++L + C C F G CE ++
Sbjct: 1307 VNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 130 bits (328), Expect = 7e-30
Identities = 65/187 (34%), Positives = 87/187 (46%), Gaps = 40/187 (21%)
Query: 277 PCLNGGKCID----------------------------DCVTGNPS-----YTCSCLSGF 303
PCL+GG C D C+ GN S Y C+C G+
Sbjct: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGY 1206
Query: 304 TGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSP---CDTKE--- 357
TG C +D++ C S C NG TC N + C C F G C ++ P C ++
Sbjct: 1207 TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNL 1266
Query: 358 -CQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP 416
C +GG C C+C+ G+TG CE D+D+C+ DPC+NGG C DL+ + CLC
Sbjct: 1267 TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVA 1326
Query: 417 FKGLRCE 423
F G RCE
Sbjct: 1327 FAGERCE 1333
Score = 129 bits (325), Expect = 2e-29
Identities = 70/197 (35%), Positives = 91/197 (46%), Gaps = 11/197 (5%)
Query: 508 CNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS--PCDSDPCFNGGSCDAHDDSYTC 565
CN N C GG C + SY C C + H + C S+PC +G +C +Y C
Sbjct: 1143 CNSNP-CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHC 1200
Query: 566 ECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCAS 625
C G+ G +CE + C S C NG TC Y C C FTG+ C + S
Sbjct: 1201 TCEPGYTGVNCEVDIDN-CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
Query: 626 G------PCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 679
G C+NGG C + + KC C PGF+G CE C PCVNGG C+D F
Sbjct: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
Query: 680 FCHCQAGYMGRRCQAEV 696
C C + G RC+ ++
Sbjct: 1320 QCLCDVAFAGERCEVDL 1336
Score = 118 bits (295), Expect = 5e-26
Identities = 67/207 (32%), Positives = 92/207 (44%), Gaps = 17/207 (8%)
Query: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGANTTL 487
+ C S PC +GG C D Y C CP G+ G C + D+C C +G
Sbjct: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-DECFSNPCIHGNCSDRVAAYH 1199
Query: 488 CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS----LPS 543
C C G+ G+ CE +I + QC +G C+ H Y C+C + LPS
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQSH---QCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 544 P-CDSDP----CFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEA 598
C ++ C+NGG+C C C GF G+ CEK C+S PC NGG C++
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDE-CASDPCVNGGLCQDL 1315
Query: 599 GGEYHCSCPYRFTGRHCEIGKPDSCAS 625
++ C C F G CE+ D S
Sbjct: 1316 LNKFQCLCDVAFAGERCEVDLADDLIS 1342
Score = 106 bits (264), Expect = 2e-22
Identities = 45/127 (35%), Positives = 66/127 (51%), Gaps = 1/127 (0%)
Query: 790 LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 849
L+ + C ++PC +GG+C ++ +Y C CP G+ G HCE +D C S+PC HG C
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVA 1196
Query: 850 AYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPP 909
AY C C + G +CE D C S C C++ +SC C +TG+ C + P
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 910 TALKMER 916
T E+
Sbjct: 1257 TVCGNEK 1263
Score = 105 bits (263), Expect = 2e-22
Identities = 64/216 (29%), Positives = 85/216 (39%), Gaps = 53/216 (24%)
Query: 701 PEEVKHATLRFNGTRLGAVALYACDRGYSLSAP------SRIRVCQPHGVWSEPPQCLEI 754
P+E + + N G + L C+ L S P G WS L I
Sbjct: 1120 PQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLG-WSGKHCELNI 1178
Query: 755 DECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYV 814
DEC S PC+HG +C DRVA Y C C GY G +CE++ D C++H C NG +C + Y
Sbjct: 1179 DECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYS 1237
Query: 815 C---------------------------------------------RCPAGFVGVHCETE 829
C C GF G CE +
Sbjct: 1238 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKD 1297
Query: 830 VDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCE 865
+D C S PC +GG C+ + C+C +F G CE
Sbjct: 1298 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
Score = 87.0 bits (214), Expect = 1e-16
Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 42/165 (25%)
Query: 784 EGAHCELERDECRAHPCRNGGSCR------------------------------------ 807
+ + C C ++ C+N +C+
Sbjct: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
Query: 808 ----NLPG--AYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFG 861
N PG +++C+CP G+ G CET + +C + CQHGG C +C+CP + G
Sbjct: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG 142
Query: 862 YHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
CE D C SSPC C +SC C GY G C E+
Sbjct: 143 RFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
Score = 79.3 bits (194), Expect = 2e-14
Identities = 40/120 (33%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDV-------NECASQPCQNGGTCTHGI 330
C NG CI Y+C C FTG+ C NE + C NGG CT
Sbjct: 1223 CANGATCISH----TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQ 1278
Query: 331 NSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDD 390
+C C GF G CE C + C +GG CQ C+C + G CE+D+ D
Sbjct: 1279 TELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 63.9 bits (154), Expect = 1e-09
Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 64/137 (46%)
Query: 277 PCLNGGKCID-------DCVTGNPS---------YTCSCLSGFTGRRCHLDVNECASQPC 320
PC + G+C++ +TG PS Y C C GFTG C DVNEC+S PC
Sbjct: 347 PCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPC 406
Query: 321 QNGGTC---------------------------------TH---------------GINS 332
QNGGTC TH G +
Sbjct: 407 QNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHG 466
Query: 333 FRCQCPAGFGGPTCETA 349
F C CP+G+ G CE A
Sbjct: 467 FSCLCPSGYTGSLCEIA 483
Score = 60.5 bits (145), Expect = 1e-08
Identities = 28/69 (40%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 313 NECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAV 372
N C S PC NGG C + F C CPA G CE Q C C HG QCQ
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQW-CGFSPCPHGAQCQPVLQGFE 947
Query: 373 CVCQAGYTG 381
C+ A + G
Sbjct: 948 CIANAVFNG 956
Score = 56.6 bits (135), Expect = 2e-07
Identities = 26/69 (37%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 793 DECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYL 852
+ C+++PC NGG C + + C CPA G CE EV C SPC HG +C+ +
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 853 CVCPESFFG 861
C+ F G
Sbjct: 948 CIANAVFNG 956
Score = 55.5 bits (132), Expect = 4e-07
Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 621 DSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFF 680
+SC S PCHNGG C + C CP SG+ CE C SPC +G C+ F
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 681 CHCQAGYMGRRCQ 693
C A + G+ Q
Sbjct: 948 CIANAVFNGQSGQ 960
Score = 55.5 bits (132), Expect = 4e-07
Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHC 604
C S+PC NGG C + D ++C CP GK CE+ + C PC +G C+ + C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ--WCGFSPCPHGAQCQPVLQGFEC 948
Query: 605 SCPYRFTGRHCEI 617
F G+ +I
Sbjct: 949 IANAVFNGQSGQI 961
Score = 54.7 bits (130), Expect = 6e-07
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 584 CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKC 643
C S PC NGG C ++ CSCP +G+ CE + C PC +G C + ++C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE--EVQWCGFSPCPHGAQCQPVLQGFEC 948
Query: 644 DCPPGFSGRHCEI 656
F+G+ +I
Sbjct: 949 IANAVFNGQSGQI 961
Score = 54.3 bits (129), Expect = 8e-07
Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 11/87 (12%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPCTRLFSETKAFPVWEGG 1369
C+ +PCQNG C G D +SC C PG++GR C+L + S PC + +A + E G
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPC-----KNEATCLNEIG 206
Query: 1370 ----VCHHVYKRV-YRVHQDICFKESC 1391
+C H Y V + D C+ + C
Sbjct: 207 RYTCICPHNYSGVNCELEIDECWSQPC 233
Score = 47.8 bits (112), Expect = 8e-05
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 3/95 (3%)
Query: 1302 KDIGNVPGNCSENPCQNGGTCV--PGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSE 1359
KD N+ C NPCQ TCV PG + C C PG+ G CE + +
Sbjct: 65 KDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGI 124
Query: 1360 TKAFPVWEGGVCHHVYK-RVYRVHQDICFKESCES 1393
P++ +C Y R + D C C++
Sbjct: 125 CHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQN 159
Score = 47.8 bits (112), Expect = 8e-05
Identities = 21/44 (47%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C PC NG TC A+ CDC PGF G CEL + S+PC
Sbjct: 228 CWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPC 271
Score = 46.6 bits (109), Expect = 2e-04
Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLP 810
C + C+S PC +GG C R + C C G CE E C PC +G C+ +
Sbjct: 885 CAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVL 943
Query: 811 GAYVCRCPAGFVG 823
+ C A F G
Sbjct: 944 QGFECIANAVFNG 956
Score = 45.8 bits (107), Expect = 3e-04
Identities = 21/45 (46%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDC-GPGFKGRRCE-LACIKVSRPC 1353
C+ PC +GG CV G + +SC+C G GF G CE L + S+PC
Sbjct: 266 CASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPC 310
Score = 44.7 bits (104), Expect = 6e-04
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 353 CDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCL 412
C + C +GG C C C A +G ACE +V C PC +G C ++ + C+
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECI 949
Query: 413 CAEPFKG 419
F G
Sbjct: 950 ANAVFNG 956
Score = 43.1 bits (100), Expect = 0.002
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
C PC N TC D ++C C PG+ G +CE+ + S PC
Sbjct: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPC 348
Score = 42.4 bits (98), Expect = 0.003
Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 1299 HGSKDIGNVPGNCSENPCQNGGTCVP----GADAHSCDCGPGFKGRRCELA 1345
+G +D ++ C+ C N GTC+P G SC C G+ G CE+A
Sbjct: 433 YGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIA 483
Score = 42.4 bits (98), Expect = 0.003
Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 1/70 (1%)
Query: 831 DACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHS 890
++C S+PC +GG C S + C CP G CE V C SPC C
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEV-QWCGFSPCPHGAQCQPVLQGFE 947
Query: 891 CTCKVGYTGE 900
C + G+
Sbjct: 948 CIANAVFNGQ 957
Score = 42.0 bits (97), Expect = 0.004
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
PC NGG C ++CSC + +G+ C +V C PC +G C + F C
Sbjct: 895 PCHNGGVCHSRW----DDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECI 949
Query: 337 CPAGFGG 343
A F G
Sbjct: 950 ANAVFNG 956
Score = 41.6 bits (96), Expect = 0.005
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 5/73 (6%)
Query: 389 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDAD 448
+ C +PC NGG C +++C C G CE C +PC +G C
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-----VQWCGFSPCPHGAQCQPVL 943
Query: 449 QGYVCECPEGFMG 461
QG+ C F G
Sbjct: 944 QGFECIANAVFNG 956
Score = 40.4 bits (93), Expect = 0.012
Identities = 17/39 (43%), Positives = 20/39 (51%)
Query: 661 CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCG 699
C +PC NGG C R DF C C A G+ C+ CG
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCG 929
Score = 40.4 bits (93), Expect = 0.012
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C+ NPC +GG C ++ C C G+ G+ CEL + S PC
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPC 1186
Score = 39.7 bits (91), Expect = 0.021
Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 4/62 (6%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
NC + C NG TC+ + +SC C F G+ C + + P T +E + GG
Sbjct: 1217 NCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRL----PSTVCGNEKTNLTCYNGG 1272
Query: 1370 VC 1371
C
Sbjct: 1273 NC 1274
Score = 38.5 bits (88), Expect = 0.046
Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 1/51 (1%)
Query: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRE-RVPDDCECRNGGRC 480
++C S PCHNGG C + C CP G C E + C +G +C
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQC 939
Score = 38.1 bits (87), Expect = 0.060
Identities = 16/38 (42%), Positives = 19/38 (50%)
Query: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHC 788
C+ D C SQPC G C + Y C C YEG +C
Sbjct: 670 CVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 38.1 bits (87), Expect = 0.060
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
+C NPC NGG C D SC C G+ CE
Sbjct: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE 923
Score = 37.4 bits (85), Expect = 0.10
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 315 CASQPCQNGGTCTHGINSFRCQCPAGFGGPTC 346
C SQPCQ+ G C + S++C C + GP C
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 37.0 bits (84), Expect = 0.13
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C+ +PC NGG C + C C F G RCE+
Sbjct: 1301 CASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
Score = 36.2 bits (82), Expect = 0.23
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 14/88 (15%)
Query: 1307 VPGNCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPV 1365
V GN N C NGG C C C PGF G CE + E + P
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPC 1306
Query: 1366 WEGGVCHHVYKRVYRVHQDICFK-ESCE 1392
GG+C + + ++ D+ F E CE
Sbjct: 1307 VNGGLCQDLLNK-FQCLCDVAFAGERCE 1333
Score = 35.4 bits (80), Expect = 0.39
Identities = 13/23 (56%), Positives = 15/23 (65%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDC 1333
CS NPCQNGGTC ++C C
Sbjct: 401 CSSNPCQNGGTCENLPGNYTCHC 423
Score = 35.4 bits (80), Expect = 0.39
Identities = 13/34 (38%), Positives = 19/34 (55%)
Query: 389 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRC 422
D C PC + G C++L +Y C C P++G C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 35.0 bits (79), Expect = 0.51
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 619 KPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHC 654
+ D C S PC + G C + Y+CDC + G +C
Sbjct: 672 RKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 34.7 bits (78), Expect = 0.67
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 790 LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETE 829
+ +D C + PC++ G C NL +Y C C + G +C E
Sbjct: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
Score = 34.7 bits (78), Expect = 0.67
Identities = 15/37 (40%), Positives = 19/37 (51%)
Query: 869 DPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKE 905
D C S PC RG C+ S+ C C Y G +C +E
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
Score = 34.3 bits (77), Expect = 0.87
Identities = 22/84 (26%), Positives = 29/84 (34%), Gaps = 31/84 (36%)
Query: 1311 CSENPCQNGGTCVP--------------------GADAHSCDCGPGFKGRRCELACIKVS 1350
C+ NPCQ+ G CV A + C C PGF G CE
Sbjct: 343 CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE------- 395
Query: 1351 RPCTRLFSETKAFPVWEGGVCHHV 1374
+E + P GG C ++
Sbjct: 396 ----EDVNECSSNPCQNGGTCENL 415
Score = 33.9 bits (76), Expect = 1.1
Identities = 14/34 (41%), Positives = 18/34 (52%), Gaps = 1/34 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C NPC +G C A+ C C PG+ G CE+
Sbjct: 1181 CFSNPCIHGN-CSDRVAAYHCTCEPGYTGVNCEV 1213
Score = 33.5 bits (75), Expect = 1.5
Identities = 14/34 (41%), Positives = 19/34 (55%)
Query: 831 DACDSSPCQHGGRCESGGGAYLCVCPESFFGYHC 864
D C+S PCQ GRC + +Y C C + G +C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 33.1 bits (74), Expect = 1.9
Identities = 13/32 (40%), Positives = 18/32 (56%)
Query: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC 576
C+S PC + G C SY C+C R + G +C
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.7 bits (73), Expect = 2.5
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDC 464
D C S PC + G C++ Y C+C + G +C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.0 bits (71), Expect = 4.3
Identities = 11/32 (34%), Positives = 17/32 (53%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
C PCQ+ G C+ ++ CDC ++G C
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 31.2 bits (69), Expect = 7.4
Identities = 21/86 (24%), Positives = 30/86 (34%), Gaps = 12/86 (13%)
Query: 661 CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA 720
C PC + G C + + C C Y G C E G RF
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAG----------RFGQDDSTGYV 725
Query: 721 LYACDRGY--SLSAPSRIRVCQPHGV 744
++ D Y ++S +R QP G+
Sbjct: 726 IFTLDESYGDTISLSMFVRTLQPSGL 751
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 270 bits (690), Expect = 7e-72
Identities = 128/235 (54%), Positives = 167/235 (71%), Gaps = 4/235 (1%)
Query: 32 YPFGAERGDAVTPKQDDGGSGLRPLSVPFPFFGAEHSGLYVNNNGIISFLKEVSQFTPVA 91
YPF + D TPK DDG S L++P FFG + +YVNNNG++SF VSQFTP +
Sbjct: 29 YPFW--QNDTKTPKVDDGSSSEIKLAIPVFFFGVPYRTVYVNNNGVVSFNVLVSQFTPES 86
Query: 92 FPIAKDRCVVAAFWADVDNRRAGDVYYREATDPAMLRRATEDVRHYFPELLDFNATWVFV 151
FP+ R VA FWADV N G++YYRE +PA+L+RAT+D+R YF ++ F+ATWVF+
Sbjct: 87 FPLTDGRAFVAPFWADVHNGIRGEIYYRETMEPAILKRATKDIRKYFKDMATFSATWVFI 146
Query: 152 ATWYRVTFFGGSSSSPVNTFQTVLITDGKLSFTIFNYESIVWTTGTHASSGGNATGLGGI 211
TW VTF+GGSS++PVNTFQ VL++DG +FT+FNY I WTTGT AS G TGLGG+
Sbjct: 147 VTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTLFNYYEINWTTGT-ASGGDPLTGLGGV 205
Query: 212 AAQAGFNAGDGQRYFSIPGSRTADMAEVETTTNVGVPGRWAFRIDDAQV-RVGGC 265
AQAGFN G+ +FS+PGSRT ++ ++ TTNV VPGRWAF++D ++ GC
Sbjct: 206 MAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVNVPGRWAFKVDGKEIDPANGC 260
Score = 50.8 bits (120), Expect = 9e-06
Identities = 70/272 (25%), Positives = 92/272 (33%), Gaps = 50/272 (18%)
Query: 278 CLNGGKCIDDCVTGNPSYT-----CSCLSGFTGRRCHLDVNECASQPCQNG-GTCTHGIN 331
CL GKC D+ S+T C+ G + C+ D ++ G N
Sbjct: 861 CLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSN 920
Query: 332 SFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDC 391
S +C G C + CQ GG N S +C A Y A DV+
Sbjct: 921 SSFLEC---HGVVNVTAYYRTCLFRLCQSGG-----NESELCDSVARYASACKNADVE-- 970
Query: 392 SPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHN---GGTCVDA- 447
VG + F L C H + C G CVD+
Sbjct: 971 --------------VGPWRTY---DFCPLECPENSHFEECITCTETCETLTLGPICVDSC 1013
Query: 448 DQGYVCECPEGF--MGLDCRERVPDDCECRNGGRCLGANTTL---CQCPLGFFGLLCEFE 502
+G C+C EG+ +G C R +C C G L N T C + + C
Sbjct: 1014 SEG--CQCDEGYALLGSQCVTR--SECGCNFEGHQLATNETFWVDLDCQIFCY---CSGT 1066
Query: 503 ITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTD 534
+ C C D YCME GG Y C TD
Sbjct: 1067 DNRVHCE-TIPCKDDEYCMEEGGLYYCQARTD 1097
Score = 30.8 bits (68), Expect = 9.6
Identities = 32/122 (26%), Positives = 42/122 (34%), Gaps = 20/122 (16%)
Query: 739 CQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE--GAHCELERDECR 796
C + + E C E E + + SC + C C GY G+ C + R EC
Sbjct: 984 CPENSHFEECITCTETCETLTLGPICVDSCSEG-----CQCDEGYALLGSQC-VTRSECG 1037
Query: 797 AH-----PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAY 851
+ N +L C C VHCET PC+ C GG Y
Sbjct: 1038 CNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCET-------IPCKDDEYCMEEGGLY 1090
Query: 852 LC 853
C
Sbjct: 1091 YC 1092
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 256 bits (655), Expect = 8e-68
Identities = 145/427 (33%), Positives = 185/427 (43%), Gaps = 64/427 (14%)
Query: 507 PCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSC---DAHDDSY 563
PC T+C G Y C P C + PC +G C +
Sbjct: 46 PCAPGTECQ-----ATESGGYTC--------GPMEPRGCATQPCHHGALCVPQGPDPTGF 92
Query: 564 TCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSC 623
C C GF G CE C+S PC +G TC+ Y C CP + G CE+ + D C
Sbjct: 93 RCYCVPGFQGPRCELDIDE-CASRPCHHGATCRNLADRYECHCPLGYAGVTCEM-EVDEC 150
Query: 624 ASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHC 683
AS PC +GG+C +G ++C C PG+ G C++ C PC +GGTC D F C C
Sbjct: 151 ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDC 210
Query: 684 QA-GYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPH 742
GY G C+ EV E A N + L + + C +C P
Sbjct: 211 AGTGYEGTHCEREV-----LECASAPCEHNASCLEGLGSFRC-------------LCWP- 251
Query: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDR---------------------VAGYLCLCST 781
G E + E DEC S PC HGG C R AG+LC C
Sbjct: 252 GYSGELCEVDE-DECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPP 310
Query: 782 GYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHG 841
G+EGA C +E DEC + PC NGG C++LP + C CP G+ G CE +VD C S PC HG
Sbjct: 311 GFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHG 370
Query: 842 GRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLA--SNGSHS--CTCKVGY 897
G C Y+C CPE++ G C C C C+ +G HS C C G
Sbjct: 371 GTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGT 430
Query: 898 TGEDCAK 904
G C +
Sbjct: 431 HGPFCGQ 437
Score = 245 bits (625), Expect = 2e-64
Identities = 133/390 (34%), Positives = 176/390 (45%), Gaps = 56/390 (14%)
Query: 542 PSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE 601
PS C SDPC G C A + G C P C++ PC +G C G +
Sbjct: 39 PSACASDPCAPGTECQATESG----------GYTCGPMEPRGCATQPCHHGALCVPQGPD 88
Query: 602 ---YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAP 658
+ C C F G CE+ D CAS PCH+G TC + +Y+C CP G++G CE+
Sbjct: 89 PTGFRCYCVPGFQGPRCELDI-DECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV 147
Query: 659 SPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGA 718
C +PC++GG+C D F C C GY G RCQ ++D E + GT
Sbjct: 148 DECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLD-----ECQSQPCAHGGTCHDL 202
Query: 719 VALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC-LEIDECRSQPCLHGGSCQDRVAGYLC 777
V + CD G E C E+ EC S PC H SC + + + C
Sbjct: 203 VNGFRCDCA---------------GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRC 247
Query: 778 LCSTGYEGAHCELERDECRAHPCRNGGSCRN-------------LPGAY--------VCR 816
LC GY G CE++ DEC + PC++GG C PGA+ +C
Sbjct: 248 LCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCH 307
Query: 817 CPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPC 876
CP GF G C EVD C S PC +GG C+ + C CP+ + G CE D C S PC
Sbjct: 308 CPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPC 367
Query: 877 GGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
G C + + C C + G DC+ +L
Sbjct: 368 LHGGTCSDTVAGYICRCPETWGGRDCSVQL 397
Score = 225 bits (573), Expect = 3e-58
Identities = 131/400 (32%), Positives = 169/400 (42%), Gaps = 66/400 (16%)
Query: 315 CASQPC---------QNGG--------------TCTHGI---------NSFRCQCPAGFG 342
CAS PC ++GG C HG FRC C GF
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQ 101
Query: 343 GPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSC 402
GP CE C ++ C HG C+ C C GY G CEM+VD+C+ PCL+GGSC
Sbjct: 102 GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSC 161
Query: 403 VDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECP-EGFMG 461
+D VG++ C+CA + G RC+ D C S PC +GGTC D G+ C+C G+ G
Sbjct: 162 LDGVGSFRCVCAPGYGGTRCQLD----LDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEG 217
Query: 462 LDCRERVPD--DCECRNGGRCL-GANTTLCQCPLGFFGLLCEF---EITAMPCNMNTQCP 515
C V + C + CL G + C C G+ G LCE E + PC +C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 516 D---------------GGYCMEHGGSYLCVCHTDHNASHS--LPSPCDSDPCFNGGSCDA 558
G + H +LC C + C S PC NGG C
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQD 337
Query: 559 HDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIG 618
+ + C CP G+ G CE+ C S PC +GGTC + Y C CP + GR C +
Sbjct: 338 LPNGFQCHCPDGYAGPTCEEDVDE-CLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSV- 395
Query: 619 KPDSCASGPCHNGGTCFHY----IGKYKCDCPPGFSGRHC 654
+ C C TC + Y C CPPG G C
Sbjct: 396 QLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 220 bits (560), Expect = 9e-57
Identities = 126/383 (32%), Positives = 172/383 (44%), Gaps = 42/383 (10%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
CG A +PC +G C+ + C C+ GF G RC LD++ECAS+PC +G
Sbjct: 63 CGPMEPRGCATQPCHHGALCVPQGPDPT-GFRCYCVPGFQGPRCELDIDECASRPCHHGA 121
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
TC + + + C CP G+ G TCE C + C HGG C GS CVC GY G C
Sbjct: 122 TCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRC 181
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCA-EPFKGLRCETGDHPVPDACLSAPCHNGGT 443
++D+D+C PC +GG+C DLV + C CA ++G CE V + C SAPC + +
Sbjct: 182 QLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCE---REVLE-CASAPCEHNAS 237
Query: 444 CVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCL------------------- 481
C++ + C C G+ G C E D+C C++GGRCL
Sbjct: 238 CLEGLGSFRCLCWPGYSGELC-EVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAF 296
Query: 482 ---GANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDH--N 536
A LC CP GF G C E+ + C +GG+C + + C C +
Sbjct: 297 SFRHAAGFLCHCPPGFEGADCGVEVDEC---ASRPCLNGGHCQDLPNGFQCHCPDGYAGP 353
Query: 537 ASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTC- 595
C SDPC +GG+C Y C CP + G+ C + C C TC
Sbjct: 354 TCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDC-SVQLTGCQGHTCPLAATCI 412
Query: 596 ---KEAGGEYHCSCPYRFTGRHC 615
+ Y C CP G C
Sbjct: 413 PIFESGVHSYVCHCPPGTHGPFC 435
Score = 193 bits (490), Expect = 1e-48
Identities = 121/423 (28%), Positives = 169/423 (39%), Gaps = 90/423 (21%)
Query: 430 PDACLS-----------------------------APCHNGGTCVDA---DQGYVCECPE 457
P AC S PCH+G CV G+ C C
Sbjct: 39 PSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVP 98
Query: 458 GFMGLDCRERVPDDC---ECRNGGRCLG-ANTTLCQCPLGFFGLLCEFEITAMPCNMNTQ 513
GF G C + D+C C +G C A+ C CPLG+ G+ CE E+ +
Sbjct: 99 GFQGPRCELDI-DECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC---ASAP 154
Query: 514 CPDGGYCMEHGGSYLCVCHTDHNASHSL--PSPCDSDPCFNGGSCDAHDDSYTCECP-RG 570
C GG C++ GS+ CVC + + C S PC +GG+C + + C+C G
Sbjct: 155 CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTG 214
Query: 571 FHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHN 630
+ G HCE+ C+S PC + +C E G + C C ++G CE+ + D CAS PC +
Sbjct: 215 YEGTHCEREVLE-CASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDE-DECASSPCQH 272
Query: 631 GGTC---------------------FHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNG 669
GG C F + + C CPPGF G C + C PC+NG
Sbjct: 273 GGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNG 332
Query: 670 GTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYS 729
G C+D F CHC GY G C+ +VD + H GT VA Y
Sbjct: 333 GHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLH-----GGTCSDTVAGY------- 380
Query: 730 LSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSC----QDRVAGYLCLCSTGYEG 785
+C+ W +++ C+ C +C + V Y+C C G G
Sbjct: 381 --------ICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHG 432
Query: 786 AHC 788
C
Sbjct: 433 PFC 435
Score = 120 bits (300), Expect = 1e-26
Identities = 55/155 (35%), Positives = 72/155 (46%), Gaps = 3/155 (1%)
Query: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLP 810
C C PCLH G+C+D + C C G+EG CE D C + PC G +
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPD 1113
Query: 811 GAYVCRCPAGFVGVHCETEVDACDSS---PCQHGGRCESGGGAYLCVCPESFFGYHCETV 867
G + CRCP GF G C V + + S C G CE G A C C E G C+
Sbjct: 1114 GRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVP 1173
Query: 868 SDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
+ PC ++PC G C A+ G C C ++G+ C
Sbjct: 1174 TLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 111 bits (278), Expect = 4e-24
Identities = 60/159 (37%), Positives = 77/159 (48%), Gaps = 14/159 (8%)
Query: 271 VCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGI 330
VC A PCL+ G C D ++ C+C G+ G RC V+ C S PC G TH
Sbjct: 1059 VC-APSPCLHDGACRDLF----DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPD 1113
Query: 331 NSFRCQCPAGFGGPTCETAQSPCDTKECQ------HGGQCQVENGSAVCVCQAGYTGAAC 384
F C+CP GFGGP C + P +KEC G C+ + +A C C G G C
Sbjct: 1114 GRFECRCPPGFGGPRC---RLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC 1170
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCE 423
++ C +PCLNGG+C G C+C F G CE
Sbjct: 1171 QVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 99.4 bits (246), Expect = 2e-20
Identities = 48/151 (31%), Positives = 67/151 (44%), Gaps = 3/151 (1%)
Query: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHC 604
C PC + G+C D++ C C G+ G CE A C S PC G G + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCE-AHVDPCHSAPCARGRCHTHPDGRFEC 1118
Query: 605 SCPYRFTGRHCEIGKP--DSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCF 662
CP F G C + P + + C +G C C C G +G+ C++ PC
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 663 RSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQ 693
+PC+NGGTC C C A + G+ C+
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 96.3 bits (238), Expect = 2e-19
Identities = 54/148 (36%), Positives = 70/148 (47%), Gaps = 13/148 (8%)
Query: 391 CSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQG 450
C+P PCL+ G+C DL + C C ++G RCE D C SAPC G D
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAH----VDPCHSAPCARGRCHTHPDGR 1115
Query: 451 YVCECPEGFMGLDCRERVPD-DCE----CRNGGRCLGANTTL-CQCPLGFFGLLCEFEIT 504
+ C CP GF G CR VP +C C +G C G + C C G G C ++
Sbjct: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC--QVP 1173
Query: 505 AMPCNMNTQCPDGGYCMEHGGSYLCVCH 532
+PC N C +GG C GG C+C+
Sbjct: 1174 TLPCEAN-PCLNGGTCRAAGGVSECICN 1200
Score = 94.7 bits (234), Expect = 5e-19
Identities = 63/193 (32%), Positives = 81/193 (41%), Gaps = 46/193 (23%)
Query: 433 CLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGA--NTTL 487
C +PC + G C D + C C G+ G C V D C C G RC
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHV-DPCHSAPCARG-RCHTHPDGRFE 1117
Query: 488 CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDS 547
C+CP GF G C + + C++N C DG SPC+
Sbjct: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDG-------------------------SPCE- 1151
Query: 548 DPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHL-CSSGPCRNGGTCKEAGGEYHCSC 606
GGS A+ C C G G+ C+ P L C + PC NGGTC+ AGG C C
Sbjct: 1152 -----GGSPAAN-----CSCLEGLAGQRCQV--PTLPCEANPCLNGGTCRAAGGVSECIC 1199
Query: 607 PYRFTGRHCEIGK 619
RF+G+ CE+ K
Sbjct: 1200 NARFSGQFCEVAK 1212
Score = 90.9 bits (224), Expect = 8e-18
Identities = 57/206 (27%), Positives = 70/206 (33%), Gaps = 57/206 (27%)
Query: 623 CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCH 682
CA PC + G C + C C PG+ G CE PC +PC G D F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 683 CQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPH 742
C G+ G RC+ L PS+
Sbjct: 1120 CPPGFGGPRCR------------------------------------LPVPSK------- 1136
Query: 743 GVWSEPPQCLEIDECR-SQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCR 801
EC + CL G C+ C C G G C++ C A+PC
Sbjct: 1137 -------------ECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCL 1183
Query: 802 NGGSCRNLPGAYVCRCPAGFVGVHCE 827
NGG+CR G C C A F G CE
Sbjct: 1184 NGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 90.9 bits (224), Expect = 8e-18
Identities = 52/153 (33%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
Query: 315 CASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCV 374
CA PC + G C ++F C C G+ GP CE PC + C G +G C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 375 CQAGYTGAACEMDVD--DCSPD-PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPD 431
C G+ G C + V +CS + CL+G C C C E G RC+ P
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP--- 1176
Query: 432 ACLSAPCHNGGTCVDADQGYVCECPEGFMGLDC 464
C + PC NGGTC A C C F G C
Sbjct: 1177 -CEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 80.1 bits (196), Expect = 1e-14
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 6/115 (5%)
Query: 583 LCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYK 642
+C+ PC + G C++ + C+C + G CE D C S PC G H G+++
Sbjct: 1059 VCAPSPCLHDGACRDLFDAFACACGPGWEGPRCE-AHVDPCHSAPCARGRCHTHPDGRFE 1117
Query: 643 CDCPPGFSGRHCEIAPSP----CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQ 693
C CPPGF G C + P P C++G CE C C G G+RCQ
Sbjct: 1118 CRCPPGFGGPRCRL-PVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQ 1171
Score = 65.5 bits (158), Expect = 4e-10
Identities = 30/73 (41%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQC 337
CL+G C G+P+ CSCL G G+RC + C + PC NGGTC C C
Sbjct: 1144 CLDGSPCEG----GSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECIC 1199
Query: 338 PAGFGGPTCETAQ 350
A F G CE A+
Sbjct: 1200 NARFSGQFCEVAK 1212
Score = 57.0 bits (136), Expect = 1e-07
Identities = 27/65 (41%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Query: 315 CASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCV 374
C+ PC NGGTC N F C CPA F GPTC Q C + C C+ VCV
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVCV 869
Query: 375 CQAGY 379
+A +
Sbjct: 870 AEATF 874
Score = 52.4 bits (124), Expect = 3e-06
Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 10/83 (12%)
Query: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHC 604
C DPCFNGG+C + + C CP F G C A+ C PC TC+E + C
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC--AQQLWCPGQPCLPPATCEEVPDGFVC 868
Query: 605 SC--------PYRFTGRHCEIGK 619
P F+G + G+
Sbjct: 869 VAEATFREGPPAAFSGHNASSGR 891
Score = 51.6 bits (122), Expect = 5e-06
Identities = 33/96 (34%), Positives = 39/96 (40%), Gaps = 12/96 (12%)
Query: 389 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDAD 448
D CSPDPC NGG+C+ ++ C C F G C C PC TC +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQ-----QLWCPGQPCLPPATCEEVP 863
Query: 449 QGYVCECPEGFMGLDCRERVPDDCECRN--GGRCLG 482
G+VC F RE P N GR LG
Sbjct: 864 DGFVCVAEATF-----REGPPAAFSGHNASSGRLLG 894
Score = 51.6 bits (122), Expect = 5e-06
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 621 DSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFF 680
D C+ PC NGGTC + C CP F+G C C PC+ TCE+ F
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFV 867
Query: 681 CHCQAGY 687
C +A +
Sbjct: 868 CVAEATF 874
Score = 51.2 bits (121), Expect = 7e-06
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 583 LCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYK 642
+CS PC NGGTC ++HC+CP FTG C + C PC TC +
Sbjct: 810 MCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC--AQQLWCPGQPCLPPATCEEVPDGFV 867
Query: 643 CDC--------PPGFSGRH 653
C P FSG +
Sbjct: 868 CVAEATFREGPPAAFSGHN 886
Score = 50.1 bits (118), Expect = 2e-05
Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query: 790 LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 849
+ D C PC NGG+C + C CPA F G C ++ C PC CE
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 850 AYLCVCPESF 859
++CV +F
Sbjct: 865 GFVCVAEATF 874
Score = 49.7 bits (117), Expect = 2e-05
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 745 WSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGG 804
W+ C+ D C PC +GG+C + C C + G C ++ C PC
Sbjct: 799 WNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPA 857
Query: 805 SCRNLPGAYVCRCPAGF 821
+C +P +VC A F
Sbjct: 858 TCEEVPDGFVCVAEATF 874
Score = 48.9 bits (115), Expect = 3e-05
Identities = 34/92 (36%), Positives = 43/92 (46%), Gaps = 10/92 (10%)
Query: 1267 AATVRSQPTASAQLENMEEAPKRVSLALQLPEHGSKDIGNV-PGNCSENPCQNGGTCVP- 1324
A TV S+P ++ + P Q E G G + P C+ PC +G CVP
Sbjct: 31 AGTVPSEPPSACASD-----PCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQ 85
Query: 1325 GAD--AHSCDCGPGFKGRRCELACIK-VSRPC 1353
G D C C PGF+G RCEL + SRPC
Sbjct: 86 GPDPTGFRCYCVPGFQGPRCELDIDECASRPC 117
Score = 48.5 bits (114), Expect = 4e-05
Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 11/62 (17%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
C+ PC +GG+C+ G + C C PG+ G RC+L E ++ P GG
Sbjct: 150 CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLD-----------LDECQSQPCAHGGT 198
Query: 1371 CH 1372
CH
Sbjct: 199 CH 200
Score = 46.6 bits (109), Expect = 2e-04
Identities = 65/267 (24%), Positives = 93/267 (34%), Gaps = 44/267 (16%)
Query: 661 CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA 720
C PCV+GG+C D T F C C + G C +E+ AT G A
Sbjct: 609 CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCA--------DEIPAATFGLGGAPSSASF 660
Query: 721 LYACDRGYSLSAPSRIRVCQPHGVW------SEPPQCLEIDECRSQPCLHGGSCQ----- 769
L G +L+ +R + G+ S + + E R + + G
Sbjct: 661 LLQELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGR 720
Query: 770 -DRVAGYLCLCSTGYE-----GAHCELERDECRAHPCRNGGSCRN-LPGAYVCRCPAGFV 822
D +L + S G + G H + A GG R L + C F
Sbjct: 721 WDDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDGCHLPFF 780
Query: 823 GVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYC 882
+ + S P + GGR +S CV D C PC G C
Sbjct: 781 PLPLDNS-----SQPSELGGR-QSWNLTAGCVS------------EDMCSPDPCFNGGTC 822
Query: 883 LASNGSHSCTCKVGYTGEDCAKELFPP 909
L + CTC +TG CA++L+ P
Sbjct: 823 LVTWNDFHCTCPANFTGPTCAQQLWCP 849
Score = 45.1 bits (105), Expect = 5e-04
Identities = 17/34 (50%), Positives = 23/34 (67%)
Query: 389 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRC 422
+ C P PC++GGSCVDL ++ C CA P +G C
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
PC NGG C+ VT N + C+C + FTG C + C QPC TC + F C
Sbjct: 815 PCFNGGTCL---VTWN-DFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 337 CPAGF 341
A F
Sbjct: 870 AEATF 874
Score = 43.9 bits (102), Expect = 0.001
Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPCTR 1355
C+ +PC + G C DA +C CGPG++G RCE S PC R
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR 1105
Score = 43.5 bits (101), Expect = 0.001
Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Query: 349 AQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGN 408
++ C C +GG C V C C A +TG C + C PCL +C ++
Sbjct: 807 SEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDG 865
Query: 409 YTCLCAEPFK 418
+ C+ F+
Sbjct: 866 FVCVAEATFR 875
Score = 42.0 bits (97), Expect = 0.004
Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 18/92 (19%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDC-GPGFKGRRCELACIK-VSRPCTRLFS--------ET 1360
C PC +GGTC + CDC G G++G CE ++ S PC S
Sbjct: 188 CQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRC 247
Query: 1361 KAFPVWEGGVCHHVYKRVYRVHQDICFKESCE 1392
+P + G +C V +D C C+
Sbjct: 248 LCWPGYSGELC--------EVDEDECASSPCQ 271
Score = 41.2 bits (95), Expect = 0.007
Identities = 16/35 (45%), Positives = 18/35 (51%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELA 1345
C NPC NGGTC C C F G+ CE+A
Sbjct: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQFCEVA 1211
Score = 40.0 bits (92), Expect = 0.016
Identities = 15/38 (39%), Positives = 21/38 (55%)
Query: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHC 788
C ++CR PC+HGGSC D + C C+ + G C
Sbjct: 603 CERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 40.0 bits (92), Expect = 0.016
Identities = 16/43 (37%), Positives = 21/43 (48%)
Query: 656 IAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDC 698
++ C PC NGGTC DF C C A + G C ++ C
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWC 848
Score = 39.3 bits (90), Expect = 0.027
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C+ PC +G TC AD + C C G+ G CE+ + S PC
Sbjct: 112 CASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPC 155
Score = 37.7 bits (86), Expect = 0.079
Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 766 GSCQD-RVAGYLCLCSTGYEGA--HCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFV 822
G QD RV G+L L E CE R++CR PC +GGSC +L + C C
Sbjct: 578 GCLQDVRVDGHLLLPEDLGENVLLGCE-RREQCRPLPCVHGGSCVDLWTHFRCDCARPHR 636
Query: 823 GVHCETEVDA 832
G C E+ A
Sbjct: 637 GPTCADEIPA 646
Score = 37.0 bits (84), Expect = 0.13
Identities = 16/47 (34%), Positives = 19/47 (40%)
Query: 1297 PEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
P D G C+ PC NGG C + C C G+ G CE
Sbjct: 310 PGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE 356
Score = 37.0 bits (84), Expect = 0.13
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 314 ECASQPCQNGGTCTHGINSFRCQCPAGFGGPTC 346
+C PC +GG+C FRC C GPTC
Sbjct: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 37.0 bits (84), Expect = 0.13
Identities = 16/43 (37%), Positives = 20/43 (46%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
CS +PC NGGTC+ + C C F G C +PC
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPC 853
Score = 36.2 bits (82), Expect = 0.23
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 12/62 (19%)
Query: 1311 CSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
CS N C +G C G+ A +C C G G+RC++ + PC +A P GG
Sbjct: 1138 CSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL----PC-------EANPCLNGG 1186
Query: 1370 VC 1371
C
Sbjct: 1187 TC 1188
Score = 35.8 bits (81), Expect = 0.30
Identities = 13/39 (33%), Positives = 20/39 (51%)
Query: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP 469
+ C PC +GG+CVD + C+C G C + +P
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIP 645
Score = 35.0 bits (79), Expect = 0.51
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 22/65 (33%)
Query: 1311 CSENPCQNGGTCV---------------PGADAHS------CDCGPGFKGRRCELACIK- 1348
C+ +PCQ+GG C+ PGA + C C PGF+G C + +
Sbjct: 265 CASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDEC 324
Query: 1349 VSRPC 1353
SRPC
Sbjct: 325 ASRPC 329
Score = 33.5 bits (75), Expect = 1.5
Identities = 20/76 (26%), Positives = 28/76 (36%), Gaps = 2/76 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
C +PC +GGTC + C C + GR C + L P++E GV
Sbjct: 362 CLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPL--AATCIPIFESGV 419
Query: 1371 CHHVYKRVYRVHQDIC 1386
+V H C
Sbjct: 420 HSYVCHCPPGTHGPFC 435
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 234 bits (598), Expect = 3e-61
Identities = 246/857 (28%), Positives = 311/857 (36%), Gaps = 184/857 (21%)
Query: 282 GKCIDDC------VTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRC 335
G C DDC V G C C G+TG C C CQ G C G+ C
Sbjct: 185 GSCPDDCNDQGRCVRGR----CVCFPGYTGPSCGWP--SCPGD-CQGRGRCVQGV----C 233
Query: 336 QCPAGFGGPTCETAQSP------------------------CDTKECQHG----GQCQVE 367
C AGF GP C P C + C G G+C E
Sbjct: 234 VCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRC--E 291
Query: 368 NGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDH 427
NG CVC GYTG C V C P C G C D C+C + G C T
Sbjct: 292 NGR--CVCNPGYTGEDC--GVRSC-PRGCSQRGRCKD----GRCVCDPGYTGEDCGTRSC 342
Query: 428 PVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERV-PDDCECRNGGRCLGANTT 486
P C GG CVD C C G+ G DC R P DC R GRC
Sbjct: 343 PWD-------CGEGGRCVDGR----CVCWPGYTGEDCSTRTCPRDC--RGRGRCEDGE-- 387
Query: 487 LCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCD 546
C C G+ G C CN +C DG CVC + + C
Sbjct: 388 -CICDTGYSGDDCGVRSCPGDCNQRGRCEDGR----------CVCWPGYTGTDCGSRACP 436
Query: 547 SDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSC 606
D C G C+ + C C G+ G+ C G CR G C+ C C
Sbjct: 437 RD-CRGRGRCE----NGVCVCNAGYSGEDCGVRS----CPGDCRGRGRCESG----RCMC 483
Query: 607 PYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPC 666
+TGR C G C G C +C C PGF+G C P C
Sbjct: 484 WPGYTGRDCGT----RACPGDCRGRGRCVDG----RCVCNPGFTGEDCGSRRCP---GDC 532
Query: 667 VNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDR 726
G CED C C AGY G C G R G L + C+
Sbjct: 533 RGHGLCEDG----VCVCDAGYSGEDCSTRSCPGG--------CRGRGQCLDGRCV--CED 578
Query: 727 GYSLSAPSRIRVC----QPHGVWSEPPQ-CLE---IDECRSQPC---LHG-GSCQDRVAG 774
GYS +R C HGV + C E ++C + C HG G C++
Sbjct: 579 GYS-GEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEG--- 634
Query: 775 YLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACD 834
CLC GY G C C A CR G C + G VC C G+ G C E
Sbjct: 635 -RCLCDPGYTGPTCATRM--CPAD-CRGRGRC--VQG--VCLCHVGYGGEDCGQEEPPAS 686
Query: 835 SSPCQHGGR--CESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCT 892
+ P G R C +G CVC E F G C + P C GRG C SC
Sbjct: 687 ACPGGCGPRELCRAGQ----CVCVEGFRGPDCAIQTCP---GDCRGRGEC----HDGSCV 735
Query: 893 CKVGYTGEDCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYV--SSDG 950
CK GY GEDC +E+ ++M +EE+ V W P GP +D Y + ++ +
Sbjct: 736 CKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGP-----VDAYEIQFIPTTEGA 790
Query: 951 SYRRTDFVDRTRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEG 1010
S T V + S++ + LA G+ Y ++V +++ S PA T +
Sbjct: 791 SPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTS-----WGLPASKTITTMIDGPQD 845
Query: 1011 FEVTNVTASTISVQW-----ALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFR 1065
V VT +T+ + W + R + VS +R +V D
Sbjct: 846 LRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVR---------LEVPPEADGTLLT 896
Query: 1066 ALLPGKRYTIQLTTLSG 1082
L+PG Y + +T G
Sbjct: 897 DLMPGVEYVVTVTAERG 913
Score = 135 bits (340), Expect = 3e-31
Identities = 132/464 (28%), Positives = 165/464 (35%), Gaps = 105/464 (22%)
Query: 278 CLNGGKCIDDCVTGNPSYT-----------------------CSCLSGFTGRRCHLDVNE 314
C GG+C+D P YT C C +G++G C V
Sbjct: 346 CGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDC--GVRS 403
Query: 315 CASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCV 374
C C G C G RC C G+ G C + P ++C+ G+C ENG VCV
Sbjct: 404 CPGD-CNQRGRCEDG----RCVCWPGYTGTDCGSRACP---RDCRGRGRC--ENG--VCV 451
Query: 375 CQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACL 434
C AGY+G C V C P C G C + C+C + G C T P
Sbjct: 452 CNAGYSGEDC--GVRSC-PGDCRGRGRC----ESGRCMCWPGYTGRDCGTRACP------ 498
Query: 435 SAPCHNGGTCVDADQGYVCECPEGFMGLDC-RERVPDDCECRNGGRCLGANTTLCQCPLG 493
C G CVD C C GF G DC R P D CR G C +C C G
Sbjct: 499 -GDCRGRGRCVDGR----CVCNPGFTGEDCGSRRCPGD--CRGHGLC---EDGVCVCDAG 548
Query: 494 FFGLLCEFEITAMPCNMNTQCPDG------GY-------------CMEHG--GSYLCVCH 532
+ G C C QC DG GY C +HG +C+C
Sbjct: 549 YSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICW 608
Query: 533 TDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNG 592
+ + C S+ C G C + C C G+ G C +C + CR
Sbjct: 609 EGYVSEDCSIRTCPSN-CHGRGRC----EEGRCLCDPGYTGPTC---ATRMCPA-DCRGR 659
Query: 593 GTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGR 652
G C + C C + G C +P + A C G +C C GF G
Sbjct: 660 GRCVQG----VCLCHVGYGGEDCGQEEPPASA---CPGGCGPRELCRAGQCVCVEGFRGP 712
Query: 653 HCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEV 696
C I P C G C D C C+ GY G C EV
Sbjct: 713 DCAIQTCP---GDCRGRGECHDGS----CVCKDGYAGEDCGEEV 749
Score = 87.8 bits (216), Expect = 7e-17
Identities = 88/312 (28%), Positives = 111/312 (35%), Gaps = 63/312 (20%)
Query: 638 IGKYKCDCPPGFSGRHC------EIAPSPCFRSPCVNGGTCEDRDTD------FFCHCQA 685
+ + C C PG+ G C EI PS SP G+C D D C C
Sbjct: 151 LSRCTCSCEPGWGGPTCSDPTDAEIPPS----SPPSASGSCPDDCNDQGRCVRGRCVCFP 206
Query: 686 GYMGRRC---QAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYS---LSAPSRIRVC 739
GY G C DC G + C G+S S S R C
Sbjct: 207 GYTGPSCGWPSCPGDC-------------QGRGRCVQGVCVCRAGFSGPDCSQRSCPRGC 253
Query: 740 QPHGVWSEPPQCL-----EIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDE 794
G E +C+ D+C + C G S + R C+C+ GY G ++
Sbjct: 254 SQRG-RCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTG-------ED 305
Query: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCV 854
C C G S R C C G+ G C T D C GGRC G CV
Sbjct: 306 CGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD---CGEGGRCVDG----RCV 358
Query: 855 CPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTALKM 914
C + G C T + P C GRG C C C GY+G+DC P +
Sbjct: 359 CWPGYTGEDCSTRTCP---RDCRGRGRC----EDGECICDTGYSGDDCGVRSCPGDCNQR 411
Query: 915 ERVEESGVSISW 926
R E+ G + W
Sbjct: 412 GRCED-GRCVCW 422
Score = 58.2 bits (139), Expect = 6e-08
Identities = 67/287 (23%), Positives = 106/287 (36%), Gaps = 23/287 (8%)
Query: 898 TGEDCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDF 957
T + L P L+ + E+ ++W PP A D + V+Y +DG ++
Sbjct: 3746 TARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRA-----DSFKVSYQLADGGEPQSVQ 3800
Query: 958 VDRTRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVT 1017
VD + +LQ L G Y ++V SV+ S P T P N+T
Sbjct: 3801 VDGQARTQKLQGLIPGARYEVTVVSVRGFEE-----SEPLTGFLTTVPDGPTQLRALNLT 3855
Query: 1018 ASTISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQL 1077
+ W + V V + P A QA +VD + L+ YT
Sbjct: 3856 EGFAVLHW---KPPQNPVDTYDVQVTAPGAPPLQAETPGSAVD-YPLHDLVLHTNYT--- 3908
Query: 1078 TTLSGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYV 1137
T+ GLRG + + T T + P +L A VT +A + W P Y+
Sbjct: 3909 ATVRGLRGPNLTSPASITFTTGLEA----PRDLEAKEVTPRTALLTWTEPPVRP--AGYL 3962
Query: 1138 INVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGP 1184
++ T + G + S+ + L P Y + A+ L P
Sbjct: 3963 LSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLP 4009
Score = 41.2 bits (95), Expect = 0.007
Identities = 63/278 (22%), Positives = 95/278 (34%), Gaps = 46/278 (16%)
Query: 922 VSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQALAAGRAYNISVF 981
+S+SW P G D + V Y DG + V S + L GR Y + ++
Sbjct: 3180 LSLSWTVPQG-----RFDSFTVQYKDRDGQPQVVR-VRGEESEVTVGGLEPGRKYKMHLY 3233
Query: 982 SVKRNSNNKNDISRPAVLLARTRPRPVEG----FEVTNVTASTISVQWALHRIRHATVSG 1037
+ +S + P PVE V VT+ ++ + W +
Sbjct: 3234 GL-HEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWT---VAQGPFDS 3289
Query: 1038 VRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTL-SGLRGEEHPTESLATA 1096
V R + + QA V + L P ++Y L L +G R P E+ TA
Sbjct: 3290 FLVQYRDAQG-QPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEA-RTA 3347
Query: 1097 PTHVWTRPLPP-ANLTAARVTATSAHVVWDAPTPGSLLEAYVINVTTSQSTKSRYVPNGK 1155
P T+P P LT T S + W VP G+
Sbjct: 3348 PD---TKPSPRLGELTVTDATPDSVGLSWT-------------------------VPEGE 3379
Query: 1156 LASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLY 1193
S+ V+ R Q+ +A E+ Q EP+ Y
Sbjct: 3380 FDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKY 3417
Score = 40.0 bits (92), Expect = 0.016
Identities = 68/313 (21%), Positives = 111/313 (35%), Gaps = 47/313 (15%)
Query: 908 PPTALKMERVEES-----GVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRT---DFVD 959
PP ++E + + +S+SW P G D + V Y + DG + T D
Sbjct: 2300 PPIKPRLEELTVTDATPDSLSLSWTVPEG-----QFDHFLVQYKNGDGQPKATRVPGHED 2354
Query: 960 RTRSSH---------QLQALAAG-RAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVE 1009
R S L G R +S V + P++ P+
Sbjct: 2355 RVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLL 2414
Query: 1010 G-FEVTNVTASTISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALL 1068
G VT + ++S+ W + + R + + V + + R Q V T L
Sbjct: 2415 GELTVTGSSPDSLSLSWTVPQGRFDSFT---VQYKDRDG-RPQVVRVGGEESEVTVGGLE 2470
Query: 1069 PGKRYTIQLTTLSGLR--------GEEHPTESL--ATAPTHVWTR-PLPPANLTAARVTA 1117
PG++Y + L L R G P E + +PT T P PP +T
Sbjct: 2471 PGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTV 2530
Query: 1118 T-----SAHVVWDAPTPGSLLEAYVINVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQL 1172
T S + W P +++ + G+ + TVR L PGR+Y++
Sbjct: 2531 TGSSPDSLSLSWTVPQ--GRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKM 2588
Query: 1173 SVIAV-QSTELGP 1184
+ + + LGP
Sbjct: 2589 HLYGLHEGRRLGP 2601
Score = 38.9 bits (89), Expect = 0.035
Identities = 63/305 (20%), Positives = 106/305 (34%), Gaps = 53/305 (17%)
Query: 924 ISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQALAAGRAYNISVFSV 983
+SW P G D + V + DG + V+ S + L AGR Y ++ +
Sbjct: 1692 LSWTVPEG-----QFDSFVVQFKDKDGP--QVVPVEGHERSVTVTPLDAGRKYRFLLYGL 1744
Query: 984 KRNSNNKNDISRPAVLLART-----------RPRPVEGFEVTNVTASTISVQWALHRIRH 1032
+ ++ AR+ +PR E +VT VT +++ + W +
Sbjct: 1745 LGKKRH-GPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWT---VPE 1800
Query: 1033 ATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLS----------- 1081
V + + + Q V+ S+ + L P RY + L L
Sbjct: 1801 GQFDSFVVQYKDRDG-QPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAV 1859
Query: 1082 GLRGEEHPTESLATAPTHVWTRPLPPA------NLTAARVTATSAHVVWDAPTPGSLLEA 1135
+ TE+ TAPT PPA LT T+ + H+ W T G ++
Sbjct: 1860 AITAGREETETETTAPT-------PPAPEPHLGELTVEEATSHTLHLSW-MVTEGE-FDS 1910
Query: 1136 YVINVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLYII 1195
+ I T G T+ L RY +++ +H P H+ +
Sbjct: 1911 FEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSD----GKHVGPVHVEAL 1966
Query: 1196 TSPRD 1200
T P +
Sbjct: 1967 TVPEE 1971
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 232 bits (591), Expect = 2e-60
Identities = 208/705 (29%), Positives = 260/705 (36%), Gaps = 180/705 (25%)
Query: 281 GGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAG 340
G C +C G CS G CH +C P + G C CP G
Sbjct: 724 GEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDC-------EADCPEG 776
Query: 341 FGGPTCETAQSPCDTKECQHGGQCQVENGSAVC-----------VCQAGYTGAACEMDVD 389
G C Q C CQH +C E G+ +C VC AG+ G +C+
Sbjct: 777 RWGLGC---QEICPA--CQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQ---T 828
Query: 390 DCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETG---DHPVPDACLSAPCHNGGTCVD 446
CS C N G C G+ C CA + G C+ H PD C G D
Sbjct: 829 RCS---CANDGHCHPATGH--CSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCD 883
Query: 447 A-------DQGYV---CE--CPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGF 494
A + GYV CE CP+G G C +R C+C++G C + C CP G+
Sbjct: 884 AISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQR----CQCQHGAACDHVSGA-CTCPAGW 938
Query: 495 FGLLCEFEITA----MPCNMNTQCPDGGYCMEHGGSYLC-----------VCHTDHNASH 539
G CE A + C C G C GS LC C H H
Sbjct: 939 RGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPA-HTYGH 997
Query: 540 SLPSPCDSDPCFNGGSCD-AHDDSYTCECPRGFHGKHCEKARP---------HLCSSGPC 589
+ C CFNG SCD H C C G+ G C +A P H C C
Sbjct: 998 NCSQAC---ACFNGASCDPVHGQ---CHCAPGWMGPSCLQACPAGLYGDNCRHSCL---C 1048
Query: 590 RNGGTCKEAGGEYHCSCPYRFTGRHCEIG------KPDSCASGPCHNGGTCFHYIGKYKC 643
+NGGTC G HC+CP + G CE + SG C NGG C + G +C
Sbjct: 1049 QNGGTCDPVSG--HCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RC 1104
Query: 644 DCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEE 703
CP G++G C+ SPC R G+ G C C P
Sbjct: 1105 LCPAGWTGDKCQ---SPCLR----------------------GWFGEACAQRCSCPPGAA 1139
Query: 704 VKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQ-PC 762
H T GA C G++ S + C P G + E C ++ +C + P
Sbjct: 1140 CHHVT--------GAC---RCPPGFTGSGCE--QACPP-GSFGE--DCAQMCQCPGENPA 1183
Query: 763 LHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP-------CRNGGSCRNLPGAYVC 815
H A C C+ GY G C+ R P C NGGSC GA C
Sbjct: 1184 CH-------PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--C 1234
Query: 816 RCPAGFVGVHCETEVDACDSSP-------CQHGGRCESGGGAYLCV-----------CPE 857
RCP GF+G C P C G C+ G LC CP+
Sbjct: 1235 RCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQ 1294
Query: 858 SFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
+ FG CE + C G C ASNG SC+C +G+TG C
Sbjct: 1295 NRFGVGCE------HTCSCRNGGLCHASNG--SCSCGLGWTGRHC 1331
Score = 213 bits (543), Expect = 8e-55
Identities = 233/798 (29%), Positives = 283/798 (35%), Gaps = 202/798 (25%)
Query: 229 PGSRTADMAEVETTTNVGVPGRWAF---RIDDAQVRVGGCGHTTSVCLALRPCLNGGKCI 285
P RT + E + GRW I A C T CL L P G +C
Sbjct: 761 PPGRTGEDCEADCPE-----GRWGLGCQEICPACQHAARCDPETGACLCL-PGFVGSRCQ 814
Query: 286 DDCVTG--NPSYTCSCLSGFTGRRCHLDVNECASQP------CQN-------GGTCTHGI 330
D C G PS C G CH C+ P CQ G C+H
Sbjct: 815 DVCPAGWYGPSCQTRCSCANDGH-CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPC 873
Query: 331 N-----------SFRCQCPAGFGGPTCETAQSP-------CDTK-ECQHGGQCQVENGSA 371
N S C C AG+ GP CE Q P C+ + +CQHG C ++ S
Sbjct: 874 NCSAGHGSCDAISGLCLCEAGYVGPRCEQ-QCPQGHFGPGCEQRCQCQHGAAC--DHVSG 930
Query: 372 VCVCQAGYTGAACE-------MDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRC-- 422
C C AG+ G CE +D S C G +C D V N +CLC +G RC
Sbjct: 931 ACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC-DAV-NGSCLCPAGRRGPRCAE 988
Query: 423 ----ETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP--------- 469
T H AC C NG +C D G C C G+MG C + P
Sbjct: 989 TCPAHTYGHNCSQACA---CFNGASC-DPVHGQ-CHCAPGWMGPSCLQACPAGLYGDNCR 1043
Query: 470 DDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC 529
C C+NGG C + C CP G+ GL CE E +P ++ C H G
Sbjct: 1044 HSCLCQNGGTCDPVSGH-CACPEGWAGLACEKE--CLPRDVRAGC-------RHSGG--- 1090
Query: 530 VCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCE---------KAR 580
C NGG CD H C CP G+ G C+ +A
Sbjct: 1091 --------------------CLNGGLCDPHTGR--CLCPAGWTGDKCQSPCLRGWFGEAC 1128
Query: 581 PHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKP-----DSCA--------SGP 627
CS C G C G C CP FTG CE P + CA +
Sbjct: 1129 AQRCS---CPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPA 1183
Query: 628 CHNG-GTCFHYIGKY--KCD--CPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCH 682
CH GTC G + C CPPG G CE C+NGG+C+ C
Sbjct: 1184 CHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCG------CLNGGSCDAATGA--CR 1235
Query: 683 CQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACD--RGYSLSAPSRIRVCQ 740
C G++G C + C P G GA ACD G L P R V
Sbjct: 1236 CPTGFLGTDCN--LTC-PQGRFGPNCTHVCGCGQGA----ACDPVTGTCLCPPGRAGVRC 1288
Query: 741 PHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE----RDECR 796
G P + + C +GG C + C C G+ G HCEL R
Sbjct: 1289 ERGC---PQNRFGVGCEHTCSCRNGGLCH--ASNGSCSCGLGWTGRHCELACPPGRYGAA 1343
Query: 797 AH---PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVD------ACDSSP-CQHGGRCES 846
H C N +C P CRC GF G CE C CQHG C+
Sbjct: 1344 CHLECSCHNNSTCE--PATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDP 1401
Query: 847 GGGAYLCVCPESFFGYHCETVSDP-CFSSPCGGR-------------GYCLASNGSHSCT 892
G C+CP F G+ CE +P F C R G CL G T
Sbjct: 1402 ISGR--CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGAT 1459
Query: 893 CKVGYTGEDCAKELFPPT 910
C + DC + F P+
Sbjct: 1460 CNL-----DCRRGQFGPS 1472
Score = 197 bits (500), Expect = 8e-50
Identities = 211/767 (27%), Positives = 281/767 (36%), Gaps = 150/767 (19%)
Query: 245 VGVPGRWAFRID-----DAQVRVGGCGHTTS---------------------VCLALRPC 278
+G GR +RI+ + GGC H S C+ + C
Sbjct: 317 LGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDC 376
Query: 279 LNGGKCIDDCVTGNPSYTCSCLSGF----TGRRCHLDVNECASQPCQNGGTCTHGINSFR 334
+ C C Y C C +G+ G C DV+ECAS CT+ SF+
Sbjct: 377 ADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE-DVDECASSRGGCEHHCTNLAGSFQ 435
Query: 335 CQCPAGFGGPTCETAQSPCDTKECQHGGQCQ-VENGSAVCVCQAGYTGAACEMDVDDCSP 393
C C AG+ SP + G+ V + V Q + DV
Sbjct: 436 CSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEE 495
Query: 394 DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVC 453
+ L G L + CL ++ H C C NGGTC+ G C
Sbjct: 496 EAELRGEH--TLTEKFVCL---------DDSFGHDCSLTC--DDCRNGGTCLLGLDG--C 540
Query: 454 ECPEGFMGLDCRERVPDD---------CECRNGGRCLGANTTLCQCPLGFFGLLCEFEIT 504
+CPEG+ GL C E P D C C+NGG C + T C+CP G G CE
Sbjct: 541 DCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTC-DSVTGACRCPPGVSGTNCEDGCP 599
Query: 505 ----AMPCNMNTQCPDGGYCMEHGGSYLC-------VCHTDHNASHSLPSPCDSDPCF-- 551
C C + G C G+ LC CH P + C
Sbjct: 600 KGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQP 659
Query: 552 NGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGP-------CRNGGTCKEAGGEYHC 604
+ SCD D S C C GF G+ C+ A L GP C G C GE
Sbjct: 660 HTQSCDKRDGS--CSCKAGFRGERCQ-AECELGYFGPGCWQACTCPVGVACDSVSGECGK 716
Query: 605 SCPYRF----TGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSP 660
CP F G+ C +G S C GG H + +C CPPG +G CE A P
Sbjct: 717 RCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGV-TGQCRCPPGRTGEDCE-ADCP 774
Query: 661 CFR---------SPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCG--PPEEVKHATL 709
R C + C D +T C C G++G RCQ G P +
Sbjct: 775 EGRWGLGCQEICPACQHAARC-DPETG-ACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSC 832
Query: 710 RFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPC---LHGG 766
+G A +C G+ + S R C G W P C S PC G
Sbjct: 833 ANDGHCHPATGHCSCAPGW--TGFSCQRACDT-GHWG--PDC-------SHPCNCSAGHG 880
Query: 767 SCQDRVAGYLCLCSTGYEGAHCELERDECRAHP-------CRNGGSCRNLPGAYVCRCPA 819
SC D ++G LCLC GY G CE + + P C++G +C ++ GA C CPA
Sbjct: 881 SC-DAISG-LCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA--CTCPA 936
Query: 820 GFVGVHCETE-------VDACDSSPCQHGGRCESGGGAYLC-----------VCPESFFG 861
G+ G CE +D + C G C++ G+ LC CP +G
Sbjct: 937 GWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYG 996
Query: 862 YHCETVSDPCFS----SPCGGRGYCLASNGSHSC--TCKVGYTGEDC 902
++C CF+ P G+ +C SC C G G++C
Sbjct: 997 HNCSQAC-ACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNC 1042
Score = 193 bits (491), Expect = 9e-49
Identities = 218/742 (29%), Positives = 272/742 (36%), Gaps = 149/742 (20%)
Query: 266 GHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCH-------LDVNECASQ 318
GH S L C NGG C+ + G C C G+TG C+ N S
Sbjct: 517 GHDCS--LTCDDCRNGGTCLLG-LDG-----CDCPEGWTGLICNETCPPDTFGKNCSFSC 568
Query: 319 PCQNGGTCTHGINSFRCQCPAGFGGPTCETA------QSPCDTK-ECQHGGQCQVENGSA 371
CQNGGTC + C+CP G G CE C K C + G+C G+
Sbjct: 569 SCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA- 625
Query: 372 VCVCQAGYTGAACEMDVDDCSPDP-CLNGGSCVDL------VGNYTCLCAEPFKGLRCET 424
C+C G G C + + P C CV + +C C F+G RC+
Sbjct: 626 -CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQA 684
Query: 425 GDH--------------PVPDACLSAPCHNGGTCVDADQGYVC--ECPEGFMGLDCRERV 468
PV AC S G C QG C ECP G G++C
Sbjct: 685 ECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNC---- 740
Query: 469 PDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQ-----CPDGGYCMEH 523
C C G C G T C+CP G G CE + + Q C C
Sbjct: 741 SSSCSC-GGAPCHGV-TGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 798
Query: 524 GGSYLCV-------CHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC 576
G+ LC+ C A PS C N G C H + C C G+ G C
Sbjct: 799 TGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHC--HPATGHCSCAPGWTGFSC 856
Query: 577 EKARPHLCSSG--------PCR---NGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCAS 625
++A C +G PC G+C G C C + G CE P
Sbjct: 857 QRA----CDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQCPQG-HF 909
Query: 626 GP-------CHNGGTCFHYIGKYKCDCPPGFSGRHCEIA-PSPCF----RSP--CVNGGT 671
GP C +G C H G C CP G+ G CE A P+ F RS C G
Sbjct: 910 GPGCEQRCQCQHGAACDHVSG--ACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAA 967
Query: 672 CEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKH----ATLRFNGTRLGAVALYACDRG 727
C+ + C C AG G RC + P H A FNG V C
Sbjct: 968 CD--AVNGSCLCPAGRRGPRC---AETCPAHTYGHNCSQACACFNGASCDPVH-GQCHCA 1021
Query: 728 YSLSAPSRIRVCQPHGVWSEPPQCLEIDECR-SQPCLHGGSCQDRVAGYLCLCSTGYEGA 786
PS ++ C P G++ D CR S C +GG+C D V+G+ C C G+ G
Sbjct: 1022 PGWMGPSCLQAC-PAGLYG--------DNCRHSCLCQNGGTC-DPVSGH-CACPEGWAGL 1070
Query: 787 HCELE------RDECR-AHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEV------DAC 833
CE E R CR + C NGG C P C CPAG+ G C++ +AC
Sbjct: 1071 ACEKECLPRDVRAGCRHSGGCLNGGLCD--PHTGRCLCPAGWTGDKCQSPCLRGWFGEAC 1128
Query: 834 -DSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDP-CFSSPCGGRGYCLASN----- 886
C G C GA C CP F G CE P F C C N
Sbjct: 1129 AQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHP 1186
Query: 887 GSHSCTCKVGYTGEDCAKELFP 908
+ +C+C GY G C + P
Sbjct: 1187 ATGTCSCAAGYHGPSCQQRCPP 1208
Score = 188 bits (478), Expect = 3e-47
Identities = 186/619 (30%), Positives = 222/619 (35%), Gaps = 169/619 (27%)
Query: 266 GHTTSVCLALRPCLNGGKCID-----DCVTG--NPSYTCSCLSGFTGRRCHLDVNECASQ 318
GH S A C NG C C G PS +C +G G C + C
Sbjct: 996 GHNCSQACA---CFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCR---HSCL-- 1047
Query: 319 PCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKE-------CQHGGQCQVENGSA 371
CQNGGTC S C CP G+ G CE P D + C +GG C G
Sbjct: 1048 -CQNGGTCDPV--SGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGR- 1103
Query: 372 VCVCQAGYTGAAC----------EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLR 421
C+C AG+TG C E CS C G +C + G C C F G
Sbjct: 1104 -CLCPAGWTGDKCQSPCLRGWFGEACAQRCS---CPPGAACHHVTG--ACRCPPGFTGSG 1157
Query: 422 CETGDHPVP---DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD------- 471
CE P D C G C C G+ G C++R P
Sbjct: 1158 CEQACPPGSFGEDCAQMCQCPGENPACHPATG-TCSCAAGYHGPSCQQRCPPGRYGPGCE 1216
Query: 472 --CECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC 529
C C NGG C A T C+CP GF G C N CP G + G +
Sbjct: 1217 QLCGCLNGGSC-DAATGACRCPTGFLGTDC-----------NLTCPQGRF----GPNCTH 1260
Query: 530 VCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARP-------- 581
VC C G +CD TC CP G G CE+ P
Sbjct: 1261 VCG-----------------CGQGAACDPVTG--TCLCPPGRAGVRCERGCPQNRFGVGC 1301
Query: 582 -HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPD-----SC-ASGPCHNGGTC 634
H CS CRNGG C + G CSC +TGRHCE+ P +C CHN TC
Sbjct: 1302 EHTCS---CRNGGLCHASNGS--CSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTC 1356
Query: 635 FHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQA 694
G C C PGF G+ CE PC P +G C+ C CQ G
Sbjct: 1357 EPATG--TCRCGPGFYGQACE---HPC--PPGFHGAGCQG-----LCWCQHG-------- 1396
Query: 695 EVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEI 754
C P F+G + C+RG C+P G + E
Sbjct: 1397 -APCDPISGRCLCPAGFHG--------HFCERG-----------CEP-GSFGE------- 1428
Query: 755 DECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE------RDECRAH-PCRNGGSCR 807
C + GG+ D V G LCLC G GA C L+ C H C G C
Sbjct: 1429 -GCHQRCDCDGGAPCDPVTG-LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCD 1486
Query: 808 NLPGAYVCRCPAGFVGVHC 826
+ G C C G++G C
Sbjct: 1487 PVSGQ--CHCVDGYMGPTC 1503
Score = 174 bits (441), Expect = 5e-43
Identities = 153/477 (32%), Positives = 182/477 (38%), Gaps = 103/477 (21%)
Query: 264 GCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDV------NECAS 317
GC H+ CLNGG C D TG C C +G+TG +C CA
Sbjct: 1084 GCRHSGG-------CLNGGLC--DPHTGR----CLCPAGWTGDKCQSPCLRGWFGEACAQ 1130
Query: 318 Q-PCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKE-CQHGGQCQVEN-----GS 370
+ C G C H + C+CP GF G CE A P E C QC EN +
Sbjct: 1131 RCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPAT 1188
Query: 371 AVCVCQAGYTGAACEMDVDDCSPDP-------CLNGGSCVDLVGNYTCLCAEPFKG---- 419
C C AGY G +C+ P CLNGGSC G C C F G
Sbjct: 1189 GTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATG--ACRCPTGFLGTDCN 1246
Query: 420 LRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD-------- 471
L C G P+ C G C D G C CP G G+ C P +
Sbjct: 1247 LTCPQGRFG-PNCTHVCGCGQGAAC-DPVTG-TCLCPPGRAGVRCERGCPQNRFGVGCEH 1303
Query: 472 -CECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYL-C 529
C CRNGG C +N + C C LG+ G CE CP G Y +L C
Sbjct: 1304 TCSCRNGGLCHASNGS-CSCGLGWTGRHCELA-----------CPPGRY---GAACHLEC 1348
Query: 530 VCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPC 589
CH +++ C P F G +C+ CP GFHG C+ LC C
Sbjct: 1349 SCH-NNSTCEPATGTCRCGPGFYGQACEH-------PCPPGFHGAGCQG----LCW---C 1393
Query: 590 RNGGTCKEAGGEYHCSCPYRFTGRHCEIG-KPDSCASG-----PCHNGGTCFHYIGKYKC 643
++G C G C CP F G CE G +P S G C G C G C
Sbjct: 1394 QHGAPCDPISGR--CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGL--C 1449
Query: 644 DCPPGFSGRHCEI-------APSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQ 693
CPPG SG C + PS C G C+ CHC GYMG C+
Sbjct: 1450 LCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ--CHCVDGYMGPTCR 1504
Score = 173 bits (438), Expect = 1e-42
Identities = 207/781 (26%), Positives = 271/781 (34%), Gaps = 209/781 (26%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQ--PCQN------------- 322
C +GG+C+ + C C GF G RC DV+EC + CQ+
Sbjct: 133 CFHGGRCVP-----GSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCEC 187
Query: 323 ----------------------GGTCTH-----GINSFRCQCPAGF----GGPTCETAQS 351
G C H I RCQC GF G C +S
Sbjct: 188 KPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC-VRRS 246
Query: 352 PCDTK--ECQHGGQCQVENGSAVCVCQAGY----TGAACEMDVDDCSPDPCLNGGSCVDL 405
PC + C H +CQV G A C C GY G ACE DVD+C+ C++
Sbjct: 247 PCANRNGSCMH--RCQVVRGLARCECHVGYQLAADGKACE-DVDECAAGLAQCAHGCLNT 303
Query: 406 VGNYTCLCAEPFK----GLRCETGDHPVPDACLSAPCHNGGT---CVDADQGYVCECPEG 458
G++ C+C ++ G +C + + ++C +NGG C G +C CP G
Sbjct: 304 QGSFKCVCHAGYELGADGRQCYRIEMEIVNSC---EANNGGCSHGCSHTSAGPLCTCPRG 360
Query: 459 FMGLDCRERVPDDC-ECRNGGRCLGANTT-----LCQCPLGFFGLLCEFEITAMPCNMNT 512
+ LD +R D +C + C T C C G+ C
Sbjct: 361 Y-ELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGY-----RLSADGCGCEDVD 414
Query: 513 QCPD--GG---YCMEHGGSYLCVC------HTDHNASHSLPSP---CDSDPCF------- 551
+C GG +C GS+ C C H D L P D + F
Sbjct: 415 ECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHI 474
Query: 552 -----NGGSCDAHDDSYTCECPRGFHGKH--------CEKARPHLCS--SGPCRNGGTCK 596
DD E G+H + + H CS CRNGGTC
Sbjct: 475 AVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTC- 533
Query: 597 EAGGEYHCSCPYRFTGRHC-EIGKPD----SCA-SGPCHNGGTCFHYIGKYKCDCPPGFS 650
G C CP +TG C E PD +C+ S C NGGTC G C CPPG S
Sbjct: 534 -LLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTG--ACRCPPGVS 590
Query: 651 GRHCEI-APSPCFRSPCVNGGTCEDRDT---------------DFFCH--CQAGYMGRRC 692
G +CE P + C C +R FCH C G C
Sbjct: 591 GTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGC 650
Query: 693 QAEVDCGPPEEVK--------HATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQ-PHG 743
E C P F G R A C+ GY P + C P G
Sbjct: 651 SEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQA----ECELGY--FGPGCWQACTCPVG 704
Query: 744 VWSEP---------PQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDE 794
V + P + ++C G C G C S GA C +
Sbjct: 705 VACDSVSGECGKRCPAGFQGEDC-------GQECPVGTFGVNCSSSCSCGGAPCHGVTGQ 757
Query: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLC- 853
CR P R G C CP G G+ C+ + C + CQH RC+ GA LC
Sbjct: 758 CRCPPGRTGEDCE-------ADCPEGRWGLGCQ---EICPA--CQHAARCDPETGACLCL 805
Query: 854 ----------VCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCA 903
VCP ++G C+T C G+C + G C+C G+TG C
Sbjct: 806 PGFVGSRCQDVCPAGWYGPSCQT------RCSCANDGHCHPATG--HCSCAPGWTGFSCQ 857
Query: 904 K 904
+
Sbjct: 858 R 858
Score = 142 bits (359), Expect = 2e-33
Identities = 163/596 (27%), Positives = 218/596 (36%), Gaps = 117/596 (19%)
Query: 390 DCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG---TCVD 446
+CS C +GG CV C C F+G RC+ D C + HNGG CV+
Sbjct: 127 ECSASLCFHGGRCVP-GSAQPCHCPPGFQGPRCQYD----VDECRT---HNGGCQHRCVN 178
Query: 447 ADQGYVCECPEGF-MGLDCRERVP-DDCECRNGG---RCLGANTT--LCQCPLGF----F 495
Y+CEC GF + D R + + C NGG C+ T CQC GF
Sbjct: 179 TPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQED 238
Query: 496 GLLCEFEITAMPC-NMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGG 554
G C + PC N N C C G C CH + + + D D C G
Sbjct: 239 GRHC---VRRSPCANRNGSCMH--RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGL 293
Query: 555 SCDAH-----DDSYTCECPRGFH----GKHCEKARPHLCSSGPCRNGGT---CKEAGGEY 602
+ AH S+ C C G+ G+ C + + +S NGG C
Sbjct: 294 AQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGP 353
Query: 603 HCSCP--YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGF----SGRHCE- 655
C+CP Y D CA PC C + G Y+C C G+ G CE
Sbjct: 354 LCTCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYECGCYAGYRLSADGCGCED 412
Query: 656 IAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEE------------ 703
+ R C + C + F C C+AGY R + C P EE
Sbjct: 413 VDECASSRGGCEH--HCTNLAGSFQCSCEAGY--RLHEDRRGCSPLEEPMVDLDGELPFV 468
Query: 704 --VKHATL-------RFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC-LE 753
+ H + F +GA A RG + + G C L
Sbjct: 469 RPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFG-----HDCSLT 523
Query: 754 IDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE-------LERDECRAHPCRNGGSC 806
D+CR +GG+C + G C C G+ G C ++ + C+NGG+C
Sbjct: 524 CDDCR-----NGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTC 576
Query: 807 RNLPGAYVCRCPAGFVGVHCETEVDACDSS----------PCQHGGRCESGGGAYLCVCP 856
++ GA CRCP G G +CE D C C + GRC GA C+C
Sbjct: 577 DSVTGA--CRCPPGVSGTNCE---DGCPKGYYGKHCRKKCNCANRGRCHRLYGA--CLCD 629
Query: 857 ESFFGYHCETVSDP-CFSSPCGGRGYCL------ASNGSHSCTCKVGYTGEDCAKE 905
+G C P F C C+ SC+CK G+ GE C E
Sbjct: 630 PGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAE 685
Score = 119 bits (298), Expect = 2e-26
Identities = 112/362 (30%), Positives = 144/362 (39%), Gaps = 86/362 (23%)
Query: 541 LPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC----EKARPHLCSSGPCRNGGTCK 596
L + C + CF+GG C + C CP GF G C ++ R H +G C++ C
Sbjct: 124 LSAECSASLCFHGGRC-VPGSAQPCHCPPGFQGPRCQYDVDECRTH---NGGCQH--RCV 177
Query: 597 EAGGEYHCSCPYRF----TGRHCEIGKPDSCASGPCHNGGTCFHY-----IGKYKCDCPP 647
G Y C C F R C +SCA G NGG C H+ I +++C C P
Sbjct: 178 NTPGSYLCECKPGFRLHTDSRTCL--AINSCALG---NGG-CQHHCVQLTITRHRCQCRP 231
Query: 648 GF----SGRHCEIAPSPCFRSPCVN-GGTCEDRDTDF----FCHCQAGYM----GRRCQA 694
GF GRHC RSPC N G+C R C C GY G+ C+
Sbjct: 232 GFQLQEDGRHC------VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 285
Query: 695 EVDCGPP-EEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLE 753
+C + H L G+ C GY L A R QC
Sbjct: 286 VDECAAGLAQCAHGCLNTQGS-----FKCVCHAGYELGADGR--------------QCYR 326
Query: 754 ID-------ECRSQPCLHGGSCQDRVAGYLCLCSTGYE---GAHCELERDECRAHPCRNG 803
I+ E + C HG C AG LC C GYE ++ D+C PC
Sbjct: 327 IEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ- 383
Query: 804 GSCRNLPGAYVCRCPAGF----VGVHCETEVDACDSS--PCQHGGRCESGGGAYLCVCPE 857
C N PG Y C C AG+ G CE +VD C SS C+H C + G++ C C
Sbjct: 384 QVCTNNPGGYECGCYAGYRLSADGCGCE-DVDECASSRGGCEH--HCTNLAGSFQCSCEA 440
Query: 858 SF 859
+
Sbjct: 441 GY 442
Score = 108 bits (271), Expect = 3e-23
Identities = 107/384 (27%), Positives = 126/384 (32%), Gaps = 82/384 (21%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTG---------------NPSY-----TCSCLSGFT 304
C H T C P G C C G NP+ TCSC +G+
Sbjct: 1140 CHHVTGACRC-PPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYH 1198
Query: 305 GRRCHLDVNECASQP-------CQNGGTCTHGINSFRCQCPAGFGGPTCETAQ-----SP 352
G C P C NGG+C + C+CP GF G C P
Sbjct: 1199 GPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGP 1256
Query: 353 CDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDD----------CSPDPCLNGGSC 402
T C G + + C+C G G CE CS C NGG C
Sbjct: 1257 NCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS---CRNGGLC 1313
Query: 403 VDLVGNYTCLCAEPFKGLRCETGDHP--VPDAC-LSAPCHNGGTCVDAD---------QG 450
N +C C + G CE P AC L CHN TC A G
Sbjct: 1314 H--ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG 1371
Query: 451 YVCE--CPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEIT---- 504
CE CP GF G C+ C C++G C + C CP GF G CE
Sbjct: 1372 QACEHPCPPGFHGAGCQGL----CWCQHGAPC-DPISGRCLCPAGFHGHFCERGCEPGSF 1426
Query: 505 AMPCNMNTQCPDGGYCMEHGGSYLC-------VCHTDHNASHSLPSPCDSDPCFNGGSCD 557
C+ C G C G LC C+ D PS C G CD
Sbjct: 1427 GEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCD 1486
Query: 558 AHDDSYTCECPRGFHGKHCEKARP 581
S C C G+ G C + P
Sbjct: 1487 PV--SGQCHCVDGYMGPTCREGGP 1508
Score = 77.0 bits (188), Expect = 1e-13
Identities = 61/192 (31%), Positives = 76/192 (39%), Gaps = 39/192 (20%)
Query: 728 YSLSAPSRIRVCQPHGVWSEPPQ---CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE 784
Y+ A + +R C+ W + P CL EC + C HGG C A C C G++
Sbjct: 100 YTTEARTVLRCCRG---WMQQPDEEGCLSA-ECSASLCFHGGRCVPGSA-QPCHCPPGFQ 154
Query: 785 GAHCELERDECRAHPCRNGGS---CRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHG 841
G C+ + DECR H NGG C N PG+Y+C C GF +H DS C
Sbjct: 155 GPRCQYDVDECRTH---NGGCQHRCVNTPGSYLCECKPGF-RLH-------TDSRTCLAI 203
Query: 842 GRCESGGGA------------YLCVCPESF----FGYHCETVSDPCFSSPCGGRGYCLAS 885
C G G + C C F G HC S PC + C
Sbjct: 204 NSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRS-PCANRNGSCMHRCQVV 262
Query: 886 NGSHSCTCKVGY 897
G C C VGY
Sbjct: 263 RGLARCECHVGY 274
Score = 44.7 bits (104), Expect = 6e-04
Identities = 19/39 (48%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 1305 GNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
G + CS + C +GG CVPG+ A C C PGF+G RC+
Sbjct: 122 GCLSAECSASLCFHGGRCVPGS-AQPCHCPPGFQGPRCQ 159
Score = 40.8 bits (94), Expect = 0.009
Identities = 18/31 (58%), Positives = 20/31 (64%), Gaps = 2/31 (6%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
C+NGG C A SC CG G+ GR CELAC
Sbjct: 1307 CRNGGLC--HASNGSCSCGLGWTGRHCELAC 1335
Score = 38.1 bits (87), Expect = 0.060
Identities = 22/42 (52%), Positives = 23/42 (54%), Gaps = 7/42 (16%)
Query: 1310 NCSEN-PCQNGGTC--VPGADAHSCDCGPGFKGRRCELACIK 1348
NCS + CQNGGTC V GA C C PG G CE C K
Sbjct: 563 NCSFSCSCQNGGTCDSVTGA----CRCPPGVSGTNCEDGCPK 600
Score = 37.7 bits (86), Expect = 0.079
Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 1313 ENPCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
E C N TC P +C CGPGF G+ CE C
Sbjct: 1347 ECSCHNNSTCEPATG--TCRCGPGFYGQACEHPC 1378
Score = 35.8 bits (81), Expect = 0.30
Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 2/31 (6%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
C+NGGTC+ G D CDC G+ G C C
Sbjct: 527 CRNGGTCLLGLD--GCDCPEGWTGLICNETC 555
Score = 35.8 bits (81), Expect = 0.30
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 13/51 (25%)
Query: 1309 GNCSENPCQNGG---------TCVPGADAH----SCDCGPGFKGRRCELAC 1346
G+ ++PC G +C PGA H +C C PGF G CE AC
Sbjct: 1112 GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQAC 1162
Score = 34.7 bits (78), Expect = 0.67
Identities = 16/32 (50%), Positives = 18/32 (56%), Gaps = 2/32 (6%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELACI 1347
CQNGGTC P H C C G+ G CE C+
Sbjct: 1048 CQNGGTCDP-VSGH-CACPEGWAGLACEKECL 1077
Score = 32.3 bits (72), Expect = 3.3
Identities = 15/31 (48%), Positives = 17/31 (54%), Gaps = 2/31 (6%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
C N G C P A H C C PG+ G C+ AC
Sbjct: 832 CANDGHCHP-ATGH-CSCAPGWTGFSCQRAC 860
Score = 32.0 bits (71), Expect = 4.3
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 10/61 (16%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIK--VSRPCTRLFSETKAFPVWEGGVCHH 1373
C NGG C P C C G+ G +C+ C++ C + S G CHH
Sbjct: 1091 CLNGGLCDPHTGR--CLCPAGWTGDKCQSPCLRGWFGEACAQRCS------CPPGAACHH 1142
Query: 1374 V 1374
V
Sbjct: 1143 V 1143
Score = 31.6 bits (70), Expect = 5.6
Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 5/39 (12%)
Query: 1310 NCSEN-PCQNGGTCVPGADAHS-CDCGPGFKGRRCELAC 1346
NCS+ C NG +C P H C C PG+ G C AC
Sbjct: 998 NCSQACACFNGASCDP---VHGQCHCAPGWMGPSCLQAC 1033
Score = 31.6 bits (70), Expect = 5.6
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
C NGG+C A +C C GF G C L C
Sbjct: 1221 CLNGGSC--DAATGACRCPTGFLGTDCNLTC 1249
Score = 30.8 bits (68), Expect = 9.6
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
CQ+ C P A C C PGF G RC+ C
Sbjct: 789 CQHAARCDPETGA--CLCLPGFVGSRCQDVC 817
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 231 bits (588), Expect = 5e-60
Identities = 205/730 (28%), Positives = 277/730 (37%), Gaps = 148/730 (20%)
Query: 284 CIDDCVTGN--PSYTCSCLSGFTGRRCHLDVNE------CASQ-PCQNGGTCTHGINSFR 334
C ++CV G TC C G+ G C + C+++ CQNG C +
Sbjct: 103 CTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGA-- 160
Query: 335 CQCPAGFGGPTCET----------AQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
C C AGF G CE Q PC +C+HG C G C+C GYTG C
Sbjct: 161 CVCAAGFRGWRCEELCAPGTHGKGCQLPC---QCRHGASCDPRAGE--CLCAPGYTGVYC 215
Query: 385 EMDVDDCSPD----------PCLNGGSCVDLVGNYTC-------LCAEPFKGLRCETGDH 427
E + C P PC NGG+C + G C +CA+P C G
Sbjct: 216 E---ELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQP-----CPPGTF 267
Query: 428 PVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP---------DDCECRNGG 478
+ PCH+GG C D G C C G+MG C+E P C+C NGG
Sbjct: 268 G-QNCSQDCPCHHGGQC-DHVTGQ-CHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGG 324
Query: 479 RCLGANTTLCQCPLGFFG-----LLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCH- 532
+C T C+C G+ G LC + C + C H + C C
Sbjct: 325 QC-SPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQP 383
Query: 533 --TDHNASHSLPSPCDSD----PCFNGGSCDAHDDSYTCECPRGFHGKHCEKA------R 580
+ H+ + S P D PC D H + C C GF G+ C +
Sbjct: 384 GWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYG 443
Query: 581 PHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSC------ASGPCHNGGTC 634
P+ S C NGGTC G C+C + G C + P S C NG C
Sbjct: 444 PNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAAC 501
Query: 635 FHYIGKYKCDCPPGFSGRHCEI-APSPCFRSPCVNGGTCEDRD----TDFFCHCQAGYMG 689
G C C PG+ G CE+ P F C C D C C AG+ G
Sbjct: 502 SPIDGS--CSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTG 559
Query: 690 RRCQAEVDCGPPEEVKHATLRFNGTRLGAVALY--ACDRGYSLSAPSRIRVCQP----HG 743
RC + C P + ++ + G+ + +C+ P R+C P HG
Sbjct: 560 IRCDST--CPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHG 617
Query: 744 VWSEPPQCLEIDECRSQPCLH-GGSCQ--DRVAGYLC--LCSTGYEGAHCELERDECRAH 798
P C+ S+PC H G C+ +G LC +C+ GY G C +
Sbjct: 618 CAQPCPLCVH----SSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDC------AQLC 667
Query: 799 PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVD------AC-DSSPCQHGGRCESGGGAY 851
C N G+C + G+ C+C G++G C AC + C +G C + GA
Sbjct: 668 SCANNGTCSPIDGS--CQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGAC 725
Query: 852 LCV-----------CPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGE 900
C CP +FFG C V C C +G CTC+ G+TG+
Sbjct: 726 HCTPGWTGLFCTQRCPAAFFGKDCGRVCQ------CQNGASCDHISGK--CTCRTGFTGQ 777
Query: 901 DCAKELFPPT 910
C + P T
Sbjct: 778 HCEQRCAPGT 787
Score = 193 bits (490), Expect = 1e-48
Identities = 193/672 (28%), Positives = 234/672 (34%), Gaps = 138/672 (20%)
Query: 282 GKCIDDCVTGNPSYTCS--CLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPA 339
G+C+ C G C C G G C L C PCQNGGTC H C CP
Sbjct: 202 GECL--CAPGYTGVYCEELCPPGSHGAHCEL---RC---PCQNGGTCHHITGE--CACPP 251
Query: 340 GFGGPTCETAQSP------CDTK-ECQHGGQCQVENGSAVCVCQAGYTGAACEMDVD--- 389
G+ G C P C C HGGQC G C C AGY G C+ +
Sbjct: 252 GWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQ--CHCTAGYMGDRCQEECPFGS 309
Query: 390 ---DCSPD-PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPV----PDACLSAPCHNG 441
CS C NGG C G C C +KG RC+ P P L PC
Sbjct: 310 FGFQCSQHCDCHNGGQCSPTTG--ACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDAD 367
Query: 442 GTCVDADQGYVCECPEGFMGLDCRERVP-----DDCE----CRNGGRCLGANTTLCQCPL 492
T C C G+ G C E P D C+ C+NG C T C C
Sbjct: 368 NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSI-TGGCTCAP 426
Query: 493 GFFGLLCEFEITAMP----CNMNTQCPDGGYCMEHGGSYLCVCHTD-HNASHSLPSPC-- 545
GF G +C A C+ C +GG C GS C C +LP P
Sbjct: 427 GFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGT 484
Query: 546 ------DSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAG 599
+S C NG +C D S C C G+ G CE P C C A
Sbjct: 485 WGLNCNESCTCANGAACSPIDGS--CSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHAD 542
Query: 600 G----EYHCSCPYRFTGRHCEI----GK--PDSCASGPCHNGGTCFHYIGKYKCD----- 644
G HC C +TG C+ G+ P+ S C NGG+C G +C
Sbjct: 543 GCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRG 602
Query: 645 ------CPPGFSGRHCEIAPSPCFRS--PCVN-GGTCEDRD--TDFFCH--CQAGYMGRR 691
CPPGF G C C S PC + G CE + C+ C GY G+
Sbjct: 603 PLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQD 662
Query: 692 CQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC 751
C C NGT C G+ S+ C P G W P C
Sbjct: 663 CAQLCSCAN-----------NGTCSPIDGSCQCFPGWIGKDCSQ--ACPP-GFWG--PAC 706
Query: 752 LEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE-------RDECRAHPCRNGG 804
C + G SC C C+ G+ G C +D R C+NG
Sbjct: 707 FHACSCHN-----GASCSAEDGA--CHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGA 759
Query: 805 SCRNLPGAYVCR-----------CPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLC 853
SC ++ G CR C G G C+ + ++S C H C
Sbjct: 760 SCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDH--------VTGTC 811
Query: 854 VCPESFFGYHCE 865
C F G C+
Sbjct: 812 YCSPGFKGIRCD 823
Score = 156 bits (395), Expect = 1e-37
Identities = 150/510 (29%), Positives = 198/510 (38%), Gaps = 92/510 (18%)
Query: 448 DQGYVCECPEGFMGLDC-RERVPDDCECRNGGRCLGANTTLCQCPLGFF--GLLCEFEIT 504
DQ Y C + C R R+ R G R + + C CP G++ G C T
Sbjct: 47 DQIYYTRCTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQC-CP-GYYESGDFCIPLCT 104
Query: 505 AMPCNMNTQCPDGGYCMEHGGSYLCV--CHTDHNASHSLPSPCDSDPCFNGGSCDAHDDS 562
+ PD +C G C C +DH H + C C NG C+ +
Sbjct: 105 EECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHC-SNRCQ---CQNGALCNPITGA 160
Query: 563 YTCECPRGFHGKHCEKARPHLCSSGP----------CRNGGTCKEAGGEYHCSCPYRFTG 612
C C GF G CE+ LC+ G CR+G +C GE C C +TG
Sbjct: 161 --CVCAAGFRGWRCEE----LCAPGTHGKGCQLPCQCRHGASCDPRAGE--CLCAPGYTG 212
Query: 613 RHCEIGKPDSCASG----------PCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSP-- 660
+CE + C G PC NGGTC H G+ C CPPG++G C P
Sbjct: 213 VYCE----ELCPPGSHGAHCELRCPCQNGGTCHHITGE--CACPPGWTGAVCAQPCPPGT 266
Query: 661 ----CFRS-PCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGP--PEEVKHATLRFNG 713
C + PC +GG C+ CHC AGYMG RCQ E G + +H G
Sbjct: 267 FGQNCSQDCPCHHGGQCDHVTGQ--CHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGG 324
Query: 714 TRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSE----PPQCLEIDECRSQPCLHGGSCQ 769
C+ GY + R+C P G+ P C + P +CQ
Sbjct: 325 QCSPTTGACECEPGYK-GPRCQERLC-PEGLHGPGCTLPCPCDADNTISCHPVTGACTCQ 382
Query: 770 DRVAGYLC--LCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCE 827
+G+ C C GY G C+L C C+NG C ++ G C C GF+G C
Sbjct: 383 PGWSGHHCNESCPVGYYGDGCQL---PC---TCQNGADCHSITGG--CTCAPGFMGEVCA 434
Query: 828 TEVDACDSSP-------CQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCG--G 878
A P C +GG C G+ C C E + G C PC S G
Sbjct: 435 VSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTL---PCPSGTWGLNC 489
Query: 879 RGYCLASNGS------HSCTCKVGYTGEDC 902
C +NG+ SC+C G+ G+ C
Sbjct: 490 NESCTCANGAACSPIDGSCSCTPGWLGDTC 519
Score = 155 bits (392), Expect = 3e-37
Identities = 130/452 (28%), Positives = 174/452 (38%), Gaps = 107/452 (23%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQP-------CQNGGTCTHGI 330
C NG C +TG C+C GF G C + P C NGGTC+
Sbjct: 409 CQNGADC--HSITGG----CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVD 462
Query: 331 NSFRCQ-----------CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379
S C+ CP+G G C ++ C +G C +GS C C G+
Sbjct: 463 GSCTCKEGWQGLDCTLPCPSGTWGLNCN------ESCTCANGAACSPIDGS--CSCTPGW 514
Query: 380 TGAACEMDVDD------CSPD-PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPV--- 429
G CE+ D CS C + C + G+ C C + G+RC++ P
Sbjct: 515 LGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGH--CCCLAGWTGIRCDSTCPPGRWG 572
Query: 430 PDACLSAPCHNGGTCVDAD---------QGYVCE--CPEGFMGLDCRERVPDDCECRNGG 478
P+ +S C NGG+C D +G +C+ CP GF G C + P C +
Sbjct: 573 PNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCP---LCVHSS 629
Query: 479 RCLGANTTLCQCPLGFFGLLCEFEITA-----MPCNMNTQCPDGGYCMEHGGSYLCV--- 530
R + +C+C GF G LC ++ A C C + G C GS C
Sbjct: 630 RPCHHISGICECLPGFSGALCN-QVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGW 688
Query: 531 ----CHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTC-----------ECPRGFHGKH 575
C P+ + C NG SC A D + C CP F GK
Sbjct: 689 IGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKD 748
Query: 576 CEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGP-------- 627
C + +C C+NG +C G+ C+C FTG+HCE CA G
Sbjct: 749 CGR----VCQ---CQNGASCDHISGK--CTCRTGFTGQHCE----QRCAPGTFGYGCQQL 795
Query: 628 --CHNGGTCFHYIGKYKCDCPPGFSGRHCEIA 657
C N TC H G C C PGF G C+ A
Sbjct: 796 CECMNNSTCDHVTGT--CYCSPGFKGIRCDQA 825
Score = 72.4 bits (176), Expect = 3e-12
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 47/186 (25%)
Query: 266 GHTTSVCLALRPCLNGGKC--ID---DCVTGNPSYTCS--CLSGFTGRRCHLDVNECASQ 318
G+ C L C N G C ID C G CS C GF G C + C+
Sbjct: 657 GYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACF---HACS-- 711
Query: 319 PCQNGGTCTHGINSFRC-----------QCPAGFGGPTCETAQSPCDTKECQHGGQCQVE 367
C NG +C+ + C +CPA F G C C +CQ+G C
Sbjct: 712 -CHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRV---C---QCQNGASCDHI 764
Query: 368 NGSAVCVCQAGYTGAACEMDVDDCSPDP----------CLNGGSCVDLVGNYTCLCAEPF 417
+G C C+ G+TG CE C+P C+N +C + G TC C+ F
Sbjct: 765 SGK--CTCRTGFTGQHCEQR---CAPGTFGYGCQQLCECMNNSTCDHVTG--TCYCSPGF 817
Query: 418 KGLRCE 423
KG+RC+
Sbjct: 818 KGIRCD 823
Score = 49.7 bits (117), Expect = 2e-05
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 19/82 (23%)
Query: 1310 NCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCEL----------------ACIKVSRP 1352
NCS + C+NGG+C P + SC+C PGF+G C+ C+ SRP
Sbjct: 574 NCSVSCSCENGGSCSP--EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRP 631
Query: 1353 CTRLFSETKAFPVWEGGVCHHV 1374
C + + P + G +C+ V
Sbjct: 632 CHHISGICECLPGFSGALCNQV 653
Score = 39.7 bits (91), Expect = 0.021
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Query: 1305 GNVPGNCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
G+ CS++ C NGG C P A C+C PG+KG RC+
Sbjct: 308 GSFGFQCSQHCDCHNGGQCSPTTGA--CECEPGYKGPRCQ 345
Score = 38.1 bits (87), Expect = 0.060
Identities = 24/62 (38%), Positives = 29/62 (46%), Gaps = 10/62 (16%)
Query: 1315 PCQNGGTC--VPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCH 1372
PCQNGGTC + G C C PG+ G C C P T + ++ P GG C
Sbjct: 233 PCQNGGTCHHITG----ECACPPGWTGAVCAQPC----PPGTFGQNCSQDCPCHHGGQCD 284
Query: 1373 HV 1374
HV
Sbjct: 285 HV 286
Score = 37.7 bits (86), Expect = 0.079
Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 4/35 (11%)
Query: 1316 CQNGGTCVPGADAHS----CDCGPGFKGRRCELAC 1346
CQ TC GAD HS C C PGF G C ++C
Sbjct: 403 CQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSC 437
Score = 37.4 bits (85), Expect = 0.10
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 6/59 (10%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCHHV 1374
C++G +C P A C C PG+ G CE C S E + P GG CHH+
Sbjct: 191 CRHGASCDPRAG--ECLCAPGYTGVYCEELCPPGSHGA---HCELRC-PCQNGGTCHHI 243
Score = 37.4 bits (85), Expect = 0.10
Identities = 19/38 (50%), Positives = 22/38 (57%), Gaps = 3/38 (7%)
Query: 1310 NCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
NC+E+ C NG C P D SC C PG+ G CEL C
Sbjct: 488 NCNESCTCANGAACSP-IDG-SCSCTPGWLGDTCELPC 523
Score = 35.4 bits (80), Expect = 0.39
Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 3/38 (7%)
Query: 1310 NCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
+CS CQNG C P A C C GF+G RCE C
Sbjct: 141 HCSNRCQCQNGALCNPITGA--CVCAAGFRGWRCEELC 176
Score = 35.4 bits (80), Expect = 0.39
Identities = 20/43 (46%), Positives = 22/43 (51%), Gaps = 3/43 (6%)
Query: 1305 GNVPGNCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
G NCS C NGGTC P D SC C G++G C L C
Sbjct: 440 GTYGPNCSSICSCNNGGTCSP-VDG-SCTCKEGWQGLDCTLPC 480
Score = 33.9 bits (76), Expect = 1.1
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)
Query: 1305 GNVPGNCSEN-PCQNGGTC--VPGADAHSCDCGPGFKGRRCELAC 1346
G NCS++ PC +GG C V G C C G+ G RC+ C
Sbjct: 265 GTFGQNCSQDCPCHHGGQCDHVTG----QCHCTAGYMGDRCQEEC 305
Score = 33.9 bits (76), Expect = 1.1
Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 2/31 (6%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
C N GTC P D SC C PG+ G+ C AC
Sbjct: 669 CANNGTCSP-IDG-SCQCFPGWIGKDCSQAC 697
Score = 33.1 bits (74), Expect = 1.9
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 8/45 (17%)
Query: 1316 CQNGGTC--VPGADAHSCDCGPGFKGRRCELACIKVS--RPCTRL 1356
C N TC V G +C C PGFKG RC+ A + + P T++
Sbjct: 798 CMNNSTCDHVTG----TCYCSPGFKGIRCDQAALMMEELNPYTKI 838
Score = 31.2 bits (69), Expect = 7.4
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 1314 NPCQNGGTCVPGADAHSCD--CGPGFKGRRCELAC-IKVSRPCTRLFSETKAFPVWEGGV 1370
+P TC PG H C+ C G+ G C+L C + C + P + G V
Sbjct: 373 HPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEV 432
Query: 1371 C 1371
C
Sbjct: 433 C 433
Score = 31.2 bits (69), Expect = 7.4
Identities = 18/45 (40%), Positives = 21/45 (46%), Gaps = 8/45 (17%)
Query: 1302 KDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
KD G V C CQNG +C + C C GF G+ CE C
Sbjct: 747 KDCGRV---CQ---CQNGASC--DHISGKCTCRTGFTGQHCEQRC 783
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 218 bits (556), Expect = 2e-56
Identities = 112/323 (34%), Positives = 149/323 (46%), Gaps = 31/323 (9%)
Query: 550 CFNGGSCDAH--DDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTC-----KEAGGEY 602
C G C + +++C C + G CE+ C PC+N +C K+ G +
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEY--DACQRKPCQNNASCIDANEKQDGSNF 376
Query: 603 HCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCF 662
C C +TG C+ K D C PC NG TC + + C CP G+ G CE PC
Sbjct: 377 TCVCLPGYTGELCQ-SKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCA 435
Query: 663 RSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALY 722
SPC N GTC F C+C G+ G C +D H T R GT +
Sbjct: 436 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCL--- 492
Query: 723 ACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTG 782
CD GY HG++ E E +EC S PCL+ +C+D V GY C+C
Sbjct: 493 -CDPGY-------------HGLYCEE----EYNECLSAPCLNAATCRDLVNGYECVCLAE 534
Query: 783 YEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGG 842
Y+G HCEL +D C C NG +C + C C GF G C+ +++ CDS+PC HGG
Sbjct: 535 YKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGG 594
Query: 843 RCESGGGAYLCVCPESFFGYHCE 865
C Y C CP + G +CE
Sbjct: 595 SCLDQPNGYNCHCPHGWVGANCE 617
Score = 198 bits (503), Expect = 3e-50
Identities = 114/329 (34%), Positives = 152/329 (46%), Gaps = 33/329 (10%)
Query: 345 TCETAQSPCDTKECQHGGQCQVENGSAV--CVCQAGYTGAACEMDVDDCSPDPCLNGGSC 402
TC +S + EC G+C + A C C+ Y G CE + D C PC N SC
Sbjct: 306 TCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASC 364
Query: 403 VDL-----VGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPE 457
+D N+TC+C + G C++ D C+ PC NG TC+ + G+ C+CPE
Sbjct: 365 IDANEKQDGSNFTCVCLPGYTGELCQS----KIDYCILDPCRNGATCISSLSGFTCQCPE 420
Query: 458 GFMGLDCRERVPDDC---ECRNGGRCL--GANTTLCQCPLGFFGLLCEFEI---TAMPCN 509
G+ G C E+V D C C+N G C G + T C C GF G C I PC
Sbjct: 421 GYFGSACEEKV-DPCASSPCQNNGTCYVDGVHFT-CNCSPGFTGPTCAQLIDFCALSPCA 478
Query: 510 MNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLP--SPCDSDPCFNGGSCDAHDDSYTCEC 567
T C G SY C+C ++ + + C S PC N +C + Y C C
Sbjct: 479 HGT-------CRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVC 531
Query: 568 PRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGP 627
+ G HCE + C++ C NG TC G C C FTG C+I + C S P
Sbjct: 532 LAEYKGTHCELYKDP-CANVSCLNGATCDSDGLNGTCICAPGFTGEECDI-DINECDSNP 589
Query: 628 CHNGGTCFHYIGKYKCDCPPGFSGRHCEI 656
CH+GG+C Y C CP G+ G +CEI
Sbjct: 590 CHHGGSCLDQPNGYNCHCPHGWVGANCEI 618
Score = 191 bits (484), Expect = 6e-48
Identities = 103/311 (33%), Positives = 146/311 (46%), Gaps = 24/311 (7%)
Query: 320 CQNGGTCTHGIN--SFRCQCPAGFGGPTCETAQSPCDTKECQHGGQC-----QVENGSAV 372
C G CT + +F C C + G CE + C K CQ+ C + + +
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDA-CQRKPCQNNASCIDANEKQDGSNFT 377
Query: 373 CVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDA 432
CVC GYTG C+ +D C DPC NG +C+ + +TC C E + G CE D
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACE----EKVDP 433
Query: 433 CLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGANTTL-C 488
C S+PC N GTC + C C GF G C + + D C C + G C T+ C
Sbjct: 434 CASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLI-DFCALSPCAH-GTCRSVGTSYKC 491
Query: 489 QCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS--LPSPCD 546
C G+ GL CE E ++ C + C + Y CVC ++ +H PC
Sbjct: 492 LCDPGYHGLYCEEEYNEC---LSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCA 548
Query: 547 SDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSC 606
+ C NG +CD+ + TC C GF G+ C+ + C S PC +GG+C + Y+C C
Sbjct: 549 NVSCLNGATCDSDGLNGTCICAPGFTGEECD-IDINECDSNPCHHGGSCLDQPNGYNCHC 607
Query: 607 PYRFTGRHCEI 617
P+ + G +CEI
Sbjct: 608 PHGWVGANCEI 618
Score = 191 bits (484), Expect = 6e-48
Identities = 103/323 (31%), Positives = 142/323 (43%), Gaps = 34/323 (10%)
Query: 589 CRNGGTC--KEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGK-----Y 641
C G C K + + C+C ++ G CE + D+C PC N +C K +
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCE--EYDACQRKPCQNNASCIDANEKQDGSNF 376
Query: 642 KCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD-CGP 700
C C PG++G C+ C PC NG TC + F C C GY G C+ +VD C
Sbjct: 377 TCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCAS 436
Query: 701 PEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLE-IDECRS 759
+ T +G C G++ P C + ID C
Sbjct: 437 SPCQNNGTCYVDGVHFTC----NCSPGFT------------------GPTCAQLIDFCAL 474
Query: 760 QPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPA 819
PC HG +C+ Y CLC GY G +CE E +EC + PC N +CR+L Y C C A
Sbjct: 475 SPCAHG-TCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLA 533
Query: 820 GFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGR 879
+ G HCE D C + C +G C+S G C+C F G C+ + C S+PC
Sbjct: 534 EYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHG 593
Query: 880 GYCLASNGSHSCTCKVGYTGEDC 902
G CL ++C C G+ G +C
Sbjct: 594 GSCLDQPNGYNCHCPHGWVGANC 616
Score = 187 bits (474), Expect = 8e-47
Identities = 100/262 (38%), Positives = 128/262 (48%), Gaps = 16/262 (6%)
Query: 276 RPCLNGGKCIDDCVTGNPS-YTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFR 334
+PC N CID + S +TC CL G+TG C ++ C PC+NG TC ++ F
Sbjct: 356 KPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFT 415
Query: 335 CQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPD 394
CQCP G+ G CE PC + CQ+ G C V+ C C G+TG C +D C+
Sbjct: 416 CQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALS 475
Query: 395 PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCE 454
PC + G+C + +Y CLC + GL CE + CLSAPC N TC D GY C
Sbjct: 476 PCAH-GTCRSVGTSYKCLCDPGYHGLYCE----EEYNECLSAPCLNAATCRDLVNGYECV 530
Query: 455 CPEGFMGLDCRERVPDDC---ECRNGGRC--LGANTTLCQCPLGFFGLLCEFEITAMPCN 509
C + G C E D C C NG C G N T C C GF G C+ +I C+
Sbjct: 531 CLAEYKGTHC-ELYKDPCANVSCLNGATCDSDGLNGT-CICAPGFTGEECDIDIN--ECD 586
Query: 510 MNTQCPDGGYCMEHGGSYLCVC 531
N C GG C++ Y C C
Sbjct: 587 SN-PCHHGGSCLDQPNGYNCHC 607
Score = 184 bits (468), Expect = 4e-46
Identities = 115/331 (34%), Positives = 152/331 (45%), Gaps = 37/331 (11%)
Query: 470 DDCECRNGGRCL---GANTTLCQCPLGFFGLLCEFEITAM---PCNMNTQCPDGGYCMEH 523
+D EC G+C T C C + G CE E A PC N C D +
Sbjct: 315 NDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANE-KQD 372
Query: 524 GGSYLCVCHTDHNAS--HSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARP 581
G ++ CVC + S C DPC NG +C + +TC+CP G+ G CE+ +
Sbjct: 373 GSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEE-KV 431
Query: 582 HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKY 641
C+S PC+N GTC G + C+C FTG C D CA PC +G TC Y
Sbjct: 432 DPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCA-QLIDFCALSPCAHG-TCRSVGTSY 489
Query: 642 KCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD-CGP 700
KC C PG+ G +CE + C +PC+N TC D + C C A Y G C+ D C
Sbjct: 490 KCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCAN 549
Query: 701 PEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC-LEIDECRS 759
+ AT +G G + AP G E +C ++I+EC S
Sbjct: 550 VSCLNGATCDSDGLN-----------GTCICAP---------GFTGE--ECDIDINECDS 587
Query: 760 QPCLHGGSCQDRVAGYLCLCSTGYEGAHCEL 790
PC HGGSC D+ GY C C G+ GA+CE+
Sbjct: 588 NPCHHGGSCLDQPNGYNCHCPHGWVGANCEI 618
Score = 172 bits (436), Expect = 2e-42
Identities = 92/248 (37%), Positives = 115/248 (46%), Gaps = 20/248 (8%)
Query: 266 GHTTSVCLA------LRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQP 319
G+T +C + L PC NG CI +TC C G+ G C V+ CAS P
Sbjct: 383 GYTGELCQSKIDYCILDPCRNGATCISSL----SGFTCQCPEGYFGSACEEKVDPCASSP 438
Query: 320 CQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379
CQN GTC F C C GF GPTC C C HG C+ S C+C GY
Sbjct: 439 CQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTSYKCLCDPGY 497
Query: 380 TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCH 439
G CE + ++C PCLN +C DLV Y C+C +KG CE D C + C
Sbjct: 498 HGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCEL----YKDPCANVSCL 553
Query: 440 NGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGA-NTTLCQCPLGFF 495
NG TC C C GF G +C + ++C+ C +GG CL N C CP G+
Sbjct: 554 NGATCDSDGLNGTCICAPGFTGEECDIDI-NECDSNPCHHGGSCLDQPNGYNCHCPHGWV 612
Query: 496 GLLCEFEI 503
G CE +
Sbjct: 613 GANCEIHL 620
Score = 130 bits (328), Expect = 7e-30
Identities = 57/159 (35%), Positives = 79/159 (49%), Gaps = 6/159 (3%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C C AL PC +G C + SY C C G+ G C + NEC S PC N
Sbjct: 465 CAQLIDFC-ALSPCAHG-----TCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAA 518
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
TC +N + C C A + G CE + PC C +G C + + C+C G+TG C
Sbjct: 519 TCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEEC 578
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCE 423
++D+++C +PC +GGSC+D Y C C + G CE
Sbjct: 579 DIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 128 bits (322), Expect = 3e-29
Identities = 61/160 (38%), Positives = 81/160 (50%), Gaps = 6/160 (3%)
Query: 751 CLEIDECRSQPCLHGGSCQDRV-----AGYLCLCSTGYEGAHCELERDECRAHPCRNGGS 805
C E D C+ +PC + SC D + + C+C GY G C+ + D C PCRNG +
Sbjct: 347 CEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGAT 406
Query: 806 CRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCE 865
C + + C+CP G+ G CE +VD C SSPCQ+ G C G + C C F G C
Sbjct: 407 CISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCA 466
Query: 866 TVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKE 905
+ D C SPC G C + S+ C C GY G C +E
Sbjct: 467 QLIDFCALSPCA-HGTCRSVGTSYKCLCDPGYHGLYCEEE 505
Score = 115 bits (289), Expect = 2e-25
Identities = 56/175 (32%), Positives = 80/175 (45%), Gaps = 15/175 (8%)
Query: 735 RIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDE 794
++ C P + +C +C ++P A + C C Y G CE E D
Sbjct: 303 KVSTCVPGESHANDLECSGKGKCTTKPS---------EATFSCTCEEQYVGTFCE-EYDA 352
Query: 795 CRAHPCRNGGSC-----RNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 849
C+ PC+N SC + + C C G+ G C++++D C PC++G C S
Sbjct: 353 CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLS 412
Query: 850 AYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAK 904
+ C CPE +FG CE DPC SSPC G C +C C G+TG CA+
Sbjct: 413 GFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQ 467
Score = 87.8 bits (216), Expect = 7e-17
Identities = 47/123 (38%), Positives = 61/123 (49%), Gaps = 7/123 (5%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C + CL+ PCLN C D V G Y C CL+ + G C L + CA+ C NG
Sbjct: 502 CEEEYNECLSA-PCLNAATC-RDLVNG---YECVCLAEYKGTHCELYKDPCANVSCLNGA 556
Query: 325 TC-THGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAA 383
TC + G+N C C GF G C+ + CD+ C HGG C + C C G+ GA
Sbjct: 557 TCDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGAN 615
Query: 384 CEM 386
CE+
Sbjct: 616 CEI 618
Score = 77.0 bits (188), Expect = 1e-13
Identities = 45/158 (28%), Positives = 66/158 (41%), Gaps = 14/158 (8%)
Query: 800 CRNGGSCRNLPG--AYVCRCPAGFVGVHCETEVDACDSSPCQHGGRC-----ESGGGAYL 852
C G C P + C C +VG CE E DAC PCQ+ C + G +
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 853 CVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTAL 912
CVC + G C++ D C PC C++S +C C GY G C +++ P +
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437
Query: 913 KMER---VEESGVSISWNPP---NGPAARQMLDGYAVT 944
+ GV + N GP Q++D A++
Sbjct: 438 PCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALS 475
Score = 72.8 bits (177), Expect = 2e-12
Identities = 34/86 (39%), Positives = 41/86 (47%), Gaps = 15/86 (17%)
Query: 795 CRAHPCRNGGSCRNLPG------------AYVCRCPAGFVGVHCETEVDACDSSPCQHG- 841
C A PCRNGG C + P Y C CPAG G +C+ D C S+PC HG
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 842 --GRCESGGGAYLCVCPESFFGYHCE 865
S YLC+C E + G +CE
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 69.3 bits (168), Expect = 2e-11
Identities = 32/87 (36%), Positives = 41/87 (47%), Gaps = 17/87 (19%)
Query: 315 CASQPCQNGGTCTH------------GINSFRCQCPAGFGGPTCETAQSPCDTKECQHGG 362
CA+QPC+NGG CT G + C CPAG G C+ PC + C H G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHH-G 106
Query: 363 QCQVENGSA----VCVCQAGYTGAACE 385
C + S+ +C+C GY G CE
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 65.1 bits (157), Expect = 5e-10
Identities = 31/87 (35%), Positives = 42/87 (48%), Gaps = 11/87 (12%)
Query: 274 ALRPCLNGGKCID--------DCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGT 325
A +PC NGG C G P Y+C+C +G +G C L + CAS PC +G
Sbjct: 49 AAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNC 108
Query: 326 CTHGINS---FRCQCPAGFGGPTCETA 349
+ +S + C C G+ GP CE A
Sbjct: 109 SSSSSSSSDGYLCICNEGYEGPNCEQA 135
Score = 62.4 bits (150), Expect = 3e-09
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 15/86 (17%)
Query: 757 CRSQPCLHGGSCQDRVA------------GYLCLCSTGYEGAHCELERDECRAHPCRNG- 803
C +QPC +GG C R GY C C G GA+C+L D C ++PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 804 --GSCRNLPGAYVCRCPAGFVGVHCE 827
S + Y+C C G+ G +CE
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 61.2 bits (147), Expect = 7e-09
Identities = 29/92 (31%), Positives = 40/92 (43%), Gaps = 15/92 (16%)
Query: 617 IGKPDSCASGPCHNGGTCFHY----------IGK--YKCDCPPGFSGRHCEIAPSPCFRS 664
+ P CA+ PC NGG C G+ Y C CP G SG +C++ PC +
Sbjct: 42 LSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASN 101
Query: 665 PCVNGGTCEDRDTD---FFCHCQAGYMGRRCQ 693
PC +G + + C C GY G C+
Sbjct: 102 PCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 59.7 bits (143), Expect = 2e-08
Identities = 33/92 (35%), Positives = 43/92 (46%), Gaps = 16/92 (17%)
Query: 581 PHLCSSGPCRNGGTCKEA----------GGE--YHCSCPYRFTGRHCEIGKPDSCASGPC 628
P C++ PCRNGG C GE Y C+CP +G +C++ D CAS PC
Sbjct: 45 PGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL-VADPCASNPC 103
Query: 629 HNGGTCFHYIGK---YKCDCPPGFSGRHCEIA 657
H+G Y C C G+ G +CE A
Sbjct: 104 HHGNCSSSSSSSSDGYLCICNEGYEGPNCEQA 135
Score = 59.3 bits (142), Expect = 3e-08
Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 18/103 (17%)
Query: 540 SLPSPCDSDPCFNGGSC------------DAHDDSYTCECPRGFHGKHCE-KARPHLCSS 586
S P PC + PC NGG C A + Y+C CP G G +C+ A P C+S
Sbjct: 43 SAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADP--CAS 100
Query: 587 GPCRNGGTCKEAGGE---YHCSCPYRFTGRHCEIGKPDSCASG 626
PC +G + Y C C + G +CE P A+G
Sbjct: 101 NPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATG 143
Score = 56.6 bits (135), Expect = 2e-07
Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 19/94 (20%)
Query: 391 CSPDPCLNGGSCVDLVG------------NYTCLCAEPFKGLRCETGDHPVPDACLSAPC 438
C+ PC NGG C Y+C C G C+ V D C S PC
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL----VADPCASNPC 103
Query: 439 HNGG---TCVDADQGYVCECPEGFMGLDCRERVP 469
H+G + + GY+C C EG+ G +C + +P
Sbjct: 104 HHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALP 137
Score = 53.1 bits (126), Expect = 2e-06
Identities = 41/138 (29%), Positives = 49/138 (35%), Gaps = 53/138 (38%)
Query: 657 APSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRL 716
AP PC PC NGG C R P + +H
Sbjct: 44 APGPCAAQPCRNGGVCTSR------------------------PEPDPQHPAP------- 72
Query: 717 GAVALYACDRGYSLSAPSRIRV--CQPHGVWSEPPQCLEIDECRSQPCLHG---GSCQDR 771
A + GYS + P+ I CQ L D C S PC HG S
Sbjct: 73 ------AGEPGYSCTCPAGISGANCQ-----------LVADPCASNPCHHGNCSSSSSSS 115
Query: 772 VAGYLCLCSTGYEGAHCE 789
GYLC+C+ GYEG +CE
Sbjct: 116 SDGYLCICNEGYEGPNCE 133
Score = 50.4 bits (119), Expect = 1e-05
Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 20/97 (20%)
Query: 430 PDACLSAPCHNGGTCVD------------ADQGYVCECPEGFMGLDCRERVPDDCECR-- 475
P C + PC NGG C + GY C CP G G +C + V D C
Sbjct: 45 PGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANC-QLVADPCASNPC 103
Query: 476 NGGRCLGANTT-----LCQCPLGFFGLLCEFEITAMP 507
+ G C ++++ LC C G+ G CE + ++P
Sbjct: 104 HHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLP 140
Score = 47.4 bits (111), Expect = 1e-04
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 11/94 (11%)
Query: 505 AMPCNMNTQC-----PDGGYCMEHGG-SYLCVCHTDHNASHS--LPSPCDSDPCFNGG-- 554
A PC C PD + G Y C C + ++ + PC S+PC +G
Sbjct: 50 AQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCS 109
Query: 555 -SCDAHDDSYTCECPRGFHGKHCEKARPHLCSSG 587
S + D Y C C G+ G +CE+A P L ++G
Sbjct: 110 SSSSSSSDGYLCICNEGYEGPNCEQALPSLPATG 143
Score = 42.4 bits (98), Expect = 0.003
Identities = 15/32 (46%), Positives = 19/32 (59%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
C+ +PCQN GTC +C+C PGF G C
Sbjct: 434 CASSPCQNNGTCYVDGVHFTCNCSPGFTGPTC 465
Score = 41.2 bits (95), Expect = 0.007
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 16/60 (26%)
Query: 1306 NVPGNCSENPCQNGGTCV------------PGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
+ PG C+ PC+NGG C G +SC C G G C+L V+ PC
Sbjct: 43 SAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL----VADPC 98
Score = 40.8 bits (94), Expect = 0.009
Identities = 13/34 (38%), Positives = 21/34 (61%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
C NPC +GG+C+ + ++C C G+ G CE+
Sbjct: 585 CDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEI 618
Score = 38.5 bits (88), Expect = 0.046
Identities = 13/33 (39%), Positives = 18/33 (54%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C +PC+NG TC+ +C C G+ G CE
Sbjct: 396 CILDPCRNGATCISSLSGFTCQCPEGYFGSACE 428
Score = 35.8 bits (81), Expect = 0.30
Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
C+ C NG TC +C C PGF G C++ + S PC
Sbjct: 547 CANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPC 590
Score = 34.7 bits (78), Expect = 0.67
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPCTRLFSETKAFPVWEGG 1369
C+ +PC +G TC ++ C C PG+ G CE + +S PC + +E
Sbjct: 472 CALSPCAHG-TCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYE-C 529
Query: 1370 VCHHVYKRVY-RVHQDICFKESC 1391
VC YK + +++D C SC
Sbjct: 530 VCLAEYKGTHCELYKDPCANVSC 552
Score = 32.7 bits (73), Expect = 2.5
Identities = 13/38 (34%), Positives = 20/38 (52%), Gaps = 3/38 (7%)
Query: 1311 CSENPCQNGG---TCVPGADAHSCDCGPGFKGRRCELA 1345
C+ NPC +G + +D + C C G++G CE A
Sbjct: 98 CASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQA 135
Score = 32.7 bits (73), Expect = 2.5
Identities = 12/38 (31%), Positives = 18/38 (47%), Gaps = 5/38 (13%)
Query: 1311 CSENPCQNGGTCVPGADAH-----SCDCGPGFKGRRCE 1343
C PCQN +C+ + +C C PG+ G C+
Sbjct: 353 CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQ 390
Score = 30.8 bits (68), Expect = 9.6
Identities = 14/45 (31%), Positives = 18/45 (40%), Gaps = 12/45 (26%)
Query: 870 PCFSSPCGGRGYCL------------ASNGSHSCTCKVGYTGEDC 902
PC + PC G C A +SCTC G +G +C
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANC 91
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 209 bits (533), Expect = 1e-53
Identities = 117/299 (39%), Positives = 154/299 (51%), Gaps = 24/299 (8%)
Query: 404 DLVGNYTCLCAEPFKGLRCE---TGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFM 460
D G+Y C +P L C TG++ CLS G C + C C G+
Sbjct: 193 DHFGHYVC---QPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAE---CLCRPGWQ 246
Query: 461 GLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYC 520
G C E +P + CR+G C + C C G+ GL C+ ++ C ++ C +G C
Sbjct: 247 GRLCNECIPHN-GCRHG-TC--STPWQCTCDEGWGGLFCDQDLNY--CTHHSPCKNGATC 300
Query: 521 MEHGG-SYLCVC---HTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC 576
G SY C C +T + L S CDS+PC NGGSC +D Y C CP G++G HC
Sbjct: 301 SNSGQRSYTCTCRPGYTGVDCELEL-SECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHC 359
Query: 577 EKARPHLCSSGPCRNGGTCKE--AGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTC 634
E + C+ PC NGG+C+E G Y C CP FTG +CE K D C S PC NGG C
Sbjct: 360 EHSTLS-CADSPCFNGGSCRERNQGANYACECPPNFTGSNCE-KKVDRCTSNPCANGGQC 417
Query: 635 FHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQ 693
+ C C PGF+G +CE+ S C R+PC +GGTC D + C C AG+ GRRC+
Sbjct: 418 LNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCE 476
Score = 204 bits (518), Expect = 6e-52
Identities = 125/397 (31%), Positives = 165/397 (41%), Gaps = 88/397 (22%)
Query: 522 EHGGSYLCVCHTDHNASHSLPS----PCDSDPCFNG-----GSCDAHDDSYTCECPRGFH 572
+H G Y VC D N S LP C C +G G C + C C G+
Sbjct: 193 DHFGHY--VCQPDGNLS-CLPGWTGEYCQQPICLSGCHEQNGYCSKPAE---CLCRPGWQ 246
Query: 573 GKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGG 632
G+ C + PH CR+G TC + C+C + G C+ PC NG
Sbjct: 247 GRLCNECIPH----NGCRHG-TCSTP---WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGA 298
Query: 633 TCFHYIGK-YKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRR 691
TC + + Y C C PG++G CE+ S C +PC NGG+C+D++ + C C GY G
Sbjct: 299 TCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLH 358
Query: 692 CQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC 751
C+ H+TL
Sbjct: 359 CE------------HSTL------------------------------------------ 364
Query: 752 LEIDECRSQPCLHGGSCQDRVAG--YLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNL 809
C PC +GGSC++R G Y C C + G++CE + D C ++PC NGG C N
Sbjct: 365 ----SCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNR 420
Query: 810 PGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCE--TV 867
+ +CRC GF G +CE V C +PC HGG C +C CP F G CE T
Sbjct: 421 GPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS 480
Query: 868 SDPCFSSPCGGRGYCLA--SNGSHSCTCKVGYTGEDC 902
D C SSPC R C S + C C G+ G C
Sbjct: 481 IDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517
Score = 192 bits (489), Expect = 1e-48
Identities = 97/252 (38%), Positives = 126/252 (50%), Gaps = 16/252 (6%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C + C PC NG C + +G SYTC+C G+TG C L+++EC S PC+NGG
Sbjct: 281 CDQDLNYCTHHSPCKNGATCSN---SGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGG 337
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSA--VCVCQAGYTGA 382
+C + + C CP G+ G CE + C C +GG C+ N A C C +TG+
Sbjct: 338 SCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGS 397
Query: 383 ACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG 442
CE VD C+ +PC NGG C++ + C C F G CE V D C PC +GG
Sbjct: 398 NCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCEL---HVSD-CARNPCAHGG 453
Query: 443 TCVDADQGYVCECPEGFMGLDCRERVPDDC----ECRNGGRC---LGANTTLCQCPLGFF 495
TC D + G +C CP GF G C R D C N C L +T +C CP GF
Sbjct: 454 TCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFV 513
Query: 496 GLLCEFEITAMP 507
G CEF + P
Sbjct: 514 GSRCEFPVGLPP 525
Score = 188 bits (477), Expect = 4e-47
Identities = 110/325 (33%), Positives = 148/325 (45%), Gaps = 48/325 (14%)
Query: 293 PSYTCSCLSGFTGRRCHLDV---------------NECASQP---------CQNGGTCTH 328
P SCL G+TG C + EC +P C C H
Sbjct: 202 PDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRH 261
Query: 329 GINS--FRCQCPAGFGGPTCETAQSPC-DTKECQHGGQCQVE-NGSAVCVCQAGYTGAAC 384
G S ++C C G+GG C+ + C C++G C S C C+ GYTG C
Sbjct: 262 GTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDC 321
Query: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
E+++ +C +PC NGGSC D Y CLC + GL CE +C +PC NGG+C
Sbjct: 322 ELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTL----SCADSPCFNGGSC 377
Query: 445 VDADQG--YVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGAN-TTLCQCPLGFFGLL 498
+ +QG Y CECP F G +C ++V D C C NGG+CL + +C+C GF G
Sbjct: 378 RERNQGANYACECPPNFTGSNCEKKV-DRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTY 436
Query: 499 CEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNAS----HSLPSPCDSDPCFNGG 554
CE ++ C N C GG C + +C C + + C S PCFN
Sbjct: 437 CELHVS--DCARN-PCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRA 493
Query: 555 SC--DAHDDSYTCECPRGFHGKHCE 577
+C D D++ C CP GF G CE
Sbjct: 494 TCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 184 bits (467), Expect = 5e-46
Identities = 114/343 (33%), Positives = 155/343 (45%), Gaps = 50/343 (14%)
Query: 517 GGYCMEHGGSYLCV--CHTDHNASHSLPSPCDSDPCFNGGSCDA--------HDDSYT-- 564
G YC + +C+ CH + N S P+ C P + G C+ H T
Sbjct: 214 GEYCQQP----ICLSGCH-EQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPW 268
Query: 565 -CECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE-YHCSCPYRFTGRHCEIGKPDS 622
C C G+ G C++ + PC+NG TC +G Y C+C +TG CE+ +
Sbjct: 269 QCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCEL-ELSE 327
Query: 623 CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRD--TDFF 680
C S PC NGG+C Y C CPPG+ G HCE + C SPC NGG+C +R+ ++
Sbjct: 328 CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYA 387
Query: 681 CHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQ 740
C C + G C+ +VD N G L +RG PSR+ C+
Sbjct: 388 CECPPNFTGSNCEKKVD----------RCTSNPCANGGQCL---NRG-----PSRMCRCR 429
Query: 741 PH--GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELER--DECR 796
P G + E L + +C PC HGG+C D G +C C G+ G CE+ D C
Sbjct: 430 PGFTGTYCE----LHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACA 485
Query: 797 AHPCRNGGSCRN--LPGAYVCRCPAGFVGVHCETEVDACDSSP 837
+ PC N +C +VC CP GFVG CE V S P
Sbjct: 486 SSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLPPSFP 528
Score = 125 bits (313), Expect = 4e-28
Identities = 60/180 (33%), Positives = 91/180 (50%), Gaps = 17/180 (9%)
Query: 740 QPHGVWSEPPQCLEIDECRS-------QPCLHGGSCQDRVAG--YLCLCSTGYEGAHCEL 790
+ +G S+P +CL CR C+ C+ + C C G+ G C+
Sbjct: 228 EQNGYCSKPAECL----CRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQ 283
Query: 791 ERDECRAH-PCRNGGSCRNL-PGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGG 848
+ + C H PC+NG +C N +Y C C G+ GV CE E+ CDS+PC++GG C+
Sbjct: 284 DLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQE 343
Query: 849 GAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASN--GSHSCTCKVGYTGEDCAKEL 906
Y C+CP ++G HCE + C SPC G C N +++C C +TG +C K++
Sbjct: 344 DGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKV 403
Score = 54.7 bits (130), Expect = 6e-07
Identities = 43/155 (27%), Positives = 61/155 (39%), Gaps = 23/155 (14%)
Query: 775 YLCLCSTGYEGAHC----ELERDECRAHPCRNGGSCRNLPG--AYVCRCPAGFVGVH--- 825
Y +CS Y G +C + D + C+ G+ LPG C+ P G H
Sbjct: 171 YRVICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQN 230
Query: 826 --CETEVDA----------CDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPC-F 872
C + C+ +G R + + C C E + G C+ + C
Sbjct: 231 GYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTH 290
Query: 873 SSPCGGRGYCLASNG-SHSCTCKVGYTGEDCAKEL 906
SPC C S S++CTC+ GYTG DC EL
Sbjct: 291 HSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELEL 325
Score = 48.9 bits (115), Expect = 3e-05
Identities = 24/63 (38%), Positives = 28/63 (44%), Gaps = 13/63 (20%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSR-PCTRLFSETKAFPVWEGG 1369
C+ NPC NGG C+ + C C PGF G CEL +R PC GG
Sbjct: 406 CTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCA------------HGG 453
Query: 1370 VCH 1372
CH
Sbjct: 454 TCH 456
Score = 45.8 bits (107), Expect = 3e-04
Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 5/46 (10%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE---LACIKVSRPC 1353
C NPC+NGG+C D + C C PG+ G CE L+C PC
Sbjct: 328 CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSC--ADSPC 371
Score = 45.8 bits (107), Expect = 3e-04
Identities = 22/49 (44%), Positives = 27/49 (55%), Gaps = 7/49 (14%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL-----ACIKVSRPC 1353
+C+ NPC +GGTC + C C GF GRRCE+ AC S PC
Sbjct: 443 DCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDAC--ASSPC 489
Score = 39.7 bits (91), Expect = 0.021
Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 5/48 (10%)
Query: 1310 NCSENPCQNGGTC---VPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
+C+++PC NGG+C GA+ ++C+C P F G CE + S PC
Sbjct: 365 SCADSPCFNGGSCRERNQGAN-YACECPPNFTGSNCEKKVDRCTSNPC 411
Score = 38.9 bits (89), Expect = 0.035
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 1314 NPCQNGGTCV-PGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
+PC+NG TC G +++C C PG+ G CEL + S PC
Sbjct: 292 SPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPC 333
Score = 34.7 bits (78), Expect = 0.67
Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 1311 CSENPCQNGGTCVP--GADAHSCDCGPGFKGRRCE 1343
C+ +PC N TC D C+C GF G RCE
Sbjct: 484 CASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 33.9 bits (76), Expect = 1.1
Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 3/56 (5%)
Query: 265 CGHTTSV-CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQP 319
C TS+ A PC N C D T ++ C+C GF G RC V S P
Sbjct: 475 CEVRTSIDACASSPCFNRATCYTDLSTD--TFVCNCPYGFVGSRCEFPVGLPPSFP 528
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 207 bits (526), Expect = 8e-53
Identities = 238/877 (27%), Positives = 345/877 (39%), Gaps = 140/877 (15%)
Query: 330 INSFRCQCPAGFGGPTCETAQSPCDTKE-CQHGGQCQVENGSAVCVCQAGYTGAACEMDV 388
++S R QC AG G + A DT+ C G E CVC+ G+ G C
Sbjct: 133 VSSLREQCTAG-AGCCLQPATGRLDTRPFCSGRGNFSTEGCG--CVCEPGWKGPNCSEP- 188
Query: 389 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDAD 448
+C P C G C+D C+C + F G C P + C++ G CV+
Sbjct: 189 -EC-PGNCHLRGRCID----GQCICDDGFTGEDCSQLACP-------SDCNDQGKCVNG- 234
Query: 449 QGYVCECPEGFMGLDC-RERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMP 507
VC C EG+ G DC RE P C G C+ LC C GF G C P
Sbjct: 235 ---VCICFEGYAGADCSREICPVPCS-EEHGTCVDG---LCVCHDGFAGDDCN-----KP 282
Query: 508 CNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCEC 567
+N C + G C+E+ CVC C +D CF+ G C + TC C
Sbjct: 283 LCLNN-CYNRGRCVENE----CVCDEGFTGEDCSELICPND-CFDRGRCI----NGTCYC 332
Query: 568 PRGFHGKHCEKAR-PHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASG 626
GF G+ C K PH C + G C+E C C F G C +
Sbjct: 333 EEGFTGEDCGKPTCPHACHTQ-----GRCEEG----QCVCDEGFAGVDCS----EKRCPA 379
Query: 627 PCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAG 686
CHN G C +C+C GF+G + C C NG + R + C C G
Sbjct: 380 DCHNRGRCVDG----RCECDDGFTG-------ADCGELKCPNGCSGHGRCVNGQCVCDEG 428
Query: 687 YMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWS 746
Y G C +++ C P + G + +GY S S C HG
Sbjct: 429 YTGEDC-SQLRC--PNDCHSRGRCVEGKCVCEQGF----KGYDCSDMSCPNDCHQHGRCV 481
Query: 747 EPPQCLEID-----ECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCR 801
C+ D +CR + C S + C+C G+ G C + + C
Sbjct: 482 NG-MCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCA---ELSCPNDCH 537
Query: 802 NGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFG 861
G C N C C GF+G C+ + C S C GRC G C+C E F G
Sbjct: 538 GQGRCVNGQ----CVCHEGFMGKDCKEQ--RCPSD-CHGQGRCVDGQ----CICHEGFTG 586
Query: 862 YHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTALKMERVEESG 921
C S P S C G C++ C C GY+GEDC+ E+ PP L + V E
Sbjct: 587 LDCGQHSCP---SDCNNLGQCVSGR----CICNEGYSGEDCS-EVSPPKDLVVTEVTEET 638
Query: 922 VSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQALAAGRAYNISVF 981
V+++W+ N + L Y T+ +G V ++S +Q L G Y I VF
Sbjct: 639 VNLAWD--NEMRVTEYLVVYTPTH---EGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVF 693
Query: 982 SVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQWALHRIRHATVSGVRVS 1041
++ N + +R A L P P EG + ++ +++ V+W I T + +
Sbjct: 694 AILENKKSIPVSARVATYL----PAP-EGLKFKSIKETSVEVEWDPLDIAFETWEIIFRN 748
Query: 1042 IRHPEALRDQATDVDRSVDR----FTFRALLPGKRYTIQLTTL-SGLRGEEHPTESLATA 1096
+ ++ ++ +S+ R + L PG+ Y I L + + RG P T
Sbjct: 749 MN-----KEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRG---PGLKRVTT 800
Query: 1097 PTHVWTRPLPPANLTAARVTATSAHVVWDAP---TPGSLLEAYVINVTTSQSTKSRYVPN 1153
TR P+ + VT T+A + W P G L + +V ++T
Sbjct: 801 -----TRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDE 855
Query: 1154 GKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPA 1190
+ Y++ +L P Y++S+I + G S PA
Sbjct: 856 NQ---YSIGNLKPDTEYEVSLI----SRRGDMSSNPA 885
Score = 148 bits (374), Expect = 3e-35
Identities = 131/445 (29%), Positives = 165/445 (37%), Gaps = 91/445 (20%)
Query: 263 GGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQN 322
G G + L L C N G+C+++ C C GFTG C C +
Sbjct: 273 GFAGDDCNKPLCLNNCYNRGRCVEN--------ECVCDEGFTGEDCS---ELICPNDCFD 321
Query: 323 GGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGA 382
G C +G C C GF G C P C G+C+ CVC G+ G
Sbjct: 322 RGRCING----TCYCEEGFTGEDCGKPTCP---HACHTQGRCE----EGQCVCDEGFAGV 370
Query: 383 ACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG 442
C + P C N G CVD C C + F G C G+ P+ C G
Sbjct: 371 DCS---EKRCPADCHNRGRCVD----GRCECDDGFTGADC--GELKCPNG-----CSGHG 416
Query: 443 TCVDADQGYVCECPEGFMGLDCRE-RVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEF 501
CV+ C C EG+ G DC + R P+DC R GRC+ C C GF G C
Sbjct: 417 RCVNGQ----CVCDEGYTGEDCSQLRCPNDCHSR--GRCVEGK---CVCEQGFKGYDCSD 467
Query: 502 EITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDD 561
C+ + +C +G +CVC + C D C N G C
Sbjct: 468 MSCPNDCHQHGRCVNG----------MCVCDDGYTGEDCRDRQCPRD-CSNRGLC----V 512
Query: 562 SYTCECPRGFHGKHC-EKARPHLC-SSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGK 619
C C GF G C E + P+ C G C NG C C F G+ C K
Sbjct: 513 DGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNG----------QCVCHEGFMGKDC---K 559
Query: 620 PDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 679
C S CH G C +C C GF+G C P S C N G C
Sbjct: 560 EQRCPS-DCHGQGRCV----DGQCICHEGFTGLDCGQHSCP---SDCNNLGQC----VSG 607
Query: 680 FCHCQAGYMGRRCQAEVDCGPPEEV 704
C C GY G C + PP+++
Sbjct: 608 RCICNEGYSGEDCS---EVSPPKDL 629
Score = 52.4 bits (124), Expect = 3e-06
Identities = 58/269 (21%), Positives = 102/269 (37%), Gaps = 23/269 (8%)
Query: 909 PTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQ 968
P + + E+ ++SW P ++ + +TYV G VD T++ +L
Sbjct: 1713 PKEVIFSDITENSATVSWRAPTA-----QVESFRITYVPITGGTPSMVTVDGTKTQTRLV 1767
Query: 969 ALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQWALH 1028
L G Y +S+ ++K S P T G N+T S +W
Sbjct: 1768 KLIPGVEYLVSIIAMKGFEE-----SEPVSGSFTTALDGPSGLVTANITDSEALARW--- 1819
Query: 1029 RIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLSGLRGEEH 1088
+ ATV +S E + + V + + L P YT+++ E+
Sbjct: 1820 QPAIATVDSYVISYTG-EKVPEITRTVSGNTVEYALTDLEPATEYTLRIFA------EKG 1872
Query: 1089 PTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVINVTTSQSTKS 1148
P +S +T T P +LTA V + +A + W P + + Y++ + T
Sbjct: 1873 PQKS-STITAKFTTDLDSPRDLTATEVQSETALLTWRPPR--ASVTGYLLVYESVDGTVK 1929
Query: 1149 RYVPNGKLASYTVRDLLPGRRYQLSVIAV 1177
+ SY++ DL P Y + A+
Sbjct: 1930 EVIVGPDTTSYSLADLSPSTHYTAKIQAL 1958
Score = 46.6 bits (109), Expect = 2e-04
Identities = 67/296 (22%), Positives = 120/296 (40%), Gaps = 46/296 (15%)
Query: 909 PTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQ 968
P+ ++++ V ++ I+W P +DG +TY D RT +D T +Q
Sbjct: 806 PSQIEVKDVTDTTALITWFKPLAE-----IDGIELTYGIKDVPGDRTT-IDLTEDENQYS 859
Query: 969 A--LAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQWA 1026
L Y +S+ S R + ++ ++ PR + T+ ++I+++W
Sbjct: 860 IGNLKPDTEYEVSLIS--RRGDMSSNPAKETFTTGLDAPRNLRRVSQTD---NSITLEWR 914
Query: 1027 -------LHRIRHATVSGVRVSIRHPEALRDQATDVDRS---VDRFTFRALLPGKRYTIQ 1076
+RI++A +SG H E DV +S + T L PG Y I
Sbjct: 915 NGKAAIDSYRIKYAPISGGD----HAEV------DVPKSQQATTKTTLTGLRPGTEYGIG 964
Query: 1077 LTTLSGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAY 1136
+ S ++ ++ + A T + T P +L + TS ++W TP + + Y
Sbjct: 965 V---SAVKEDKESNPATINAATELDT----PKDLQVSETAETSLTLLWK--TPLAKFDRY 1015
Query: 1137 VINVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHL 1192
+N + SY +R L PG+ Y + + A E G S+PA +
Sbjct: 1016 RLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTA----EKGRHKSKPARV 1067
Score = 45.4 bits (106), Expect = 4e-04
Identities = 67/281 (23%), Positives = 113/281 (40%), Gaps = 28/281 (9%)
Query: 912 LKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDF-VDRTRSSHQLQAL 970
L + + G ++SW A+ D + VT V S +F + T+ +L+ L
Sbjct: 1535 LTISDINPYGFTVSWM-----ASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGL 1589
Query: 971 AAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQWALHR- 1029
G Y + V + K A ++ P V+ V++ T + W
Sbjct: 1590 ITGIGYEVMVSGFTQGHQTK---PLRAEIVTEAEPE-VDNLLVSDATPDGFRLSWTADEG 1645
Query: 1030 IRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLSGLRGEEHP 1089
+ V +R + + E L +R+ D L Y I+L +S +G
Sbjct: 1646 VFDNFVLKIRDTKKQSEPLEITLLAPERTRD---ITGLREATEYEIELYGIS--KGRRSQ 1700
Query: 1090 TESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVIN-VTTSQSTKS 1148
T S A A T + + P + + +T SA V W APT + +E++ I V + T S
Sbjct: 1701 TVS-AIATTAMGS----PKEVIFSDITENSATVSWRAPT--AQVESFRITYVPITGGTPS 1753
Query: 1149 RYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEP 1189
+G + L+PG Y +S+IA++ G + SEP
Sbjct: 1754 MVTVDGTKTQTRLVKLIPGVEYLVSIIAMK----GFEESEP 1790
Score = 31.6 bits (70), Expect = 5.6
Identities = 20/49 (40%), Positives = 22/49 (44%), Gaps = 9/49 (18%)
Query: 1303 DIGNVPGNCSEN----PCQNGGTCVPGADAHSCDCGPGFKGRRC-ELAC 1346
D G +CSE C N G CV G C+C GF G C EL C
Sbjct: 364 DEGFAGVDCSEKRCPADCHNRGRCVDGR----CECDDGFTGADCGELKC 408
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 206 bits (523), Expect = 2e-52
Identities = 201/745 (26%), Positives = 285/745 (38%), Gaps = 142/745 (19%)
Query: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCH---LDVNECASQPCQNGGTCTH 328
CL + + G C+D + G SY C C +GF + +DV+EC PC NG TC +
Sbjct: 1896 CLEIPNVCSHGLCVD--LQG--SYQCICHNGFKASQDQTMCMDVDECERHPCGNG-TCKN 1950
Query: 329 GINSFRCQCPAGFGGPTCETAQSPC-DTKECQ-------HGGQCQVENGSAVCVCQAGYT 380
+ S+ C C GF T + C D EC G+C E GS C+C GY
Sbjct: 1951 TVGSYNCLCYPGFE----LTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYE 2006
Query: 381 ----GAACEMDVDDCS--PDPCLNGGSCVDLVGNYTCLCAEPF--KGLRCETGDH--PVP 430
G C +D ++C P C + G+C +L G++ C+C + K C + P
Sbjct: 2007 LTPDGKNC-IDTNECVALPGSC-SPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDP 2064
Query: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFM----GLDCRERVPDDCECR-NGGRCL---G 482
+ CL G+C + G+ C CP GF+ G C + C G+C
Sbjct: 2065 NICLF------GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKA 2118
Query: 483 ANTTLCQC-----PLGFFGLLCEFEITAMPCNMNTQCPDG-------------------- 517
NTT +C P +G CE CP G
Sbjct: 2119 FNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLES 2178
Query: 518 ------GYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNG-----GSCDAHDDSYTCE 566
G C+ GS+ C C +N ++ D+D C G G+C S+ C
Sbjct: 2179 PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECN 2238
Query: 567 CPRGFHG---KHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCE--IGKPD 621
C GF +CE C+ P C G Y C+CP + R + D
Sbjct: 2239 CNEGFEPGPMMNCEDINE--CAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLD 2296
Query: 622 SCASG--PCHNGGT-CFHYIGKYKCDCPPGFSGR----------HCEIAPSPCFRSPCVN 668
CA G C + G C + IG + C CPPG + R C P C CVN
Sbjct: 2297 ECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVN 2356
Query: 669 GGTCEDRDTDFFCHCQAGYM----GRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYAC 724
+ C C G+ G C EV + + V C
Sbjct: 2357 ------IIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSEC 2410
Query: 725 ----DRGYS-------LSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCL-HGGSCQDRV 772
RG+ L ++ + PHG +IDEC+ P L G C + +
Sbjct: 2411 CCDGGRGWGHQCELCPLPGTAQYKKICPHGP-GYTTDGRDIDECKVMPNLCTNGQCINTM 2469
Query: 773 AGYLCLCSTGY----EGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFV----GV 824
+ C C GY G C ++ DEC P C+N G+Y C CP G+V G
Sbjct: 2470 GSFRCFCKVGYTTDISGTSC-IDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGK 2528
Query: 825 HCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETV-SDPCFSSP--CGGRGY 881
C+ ++D C + C + G + C CP F +H + ++ C S P CG +G
Sbjct: 2529 TCK-DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGI 2587
Query: 882 CLASNGSHSCTCKVGY----TGEDC 902
C + GS SC C+ G+ TG +C
Sbjct: 2588 CQNTPGSFSCECQRGFSLDATGLNC 2612
Score = 190 bits (483), Expect = 7e-48
Identities = 200/765 (26%), Positives = 282/765 (36%), Gaps = 203/765 (26%)
Query: 269 TSVCLALRPCLNGGKCID---DCVTGNPSYTCSCLSGFTGR--RCHLDVNECAS--QPCQ 321
T+ C + C G D C+ S+ CSC G+ G +C +D++EC++ C
Sbjct: 1362 TTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC-IDLDECSNGTHQCS 1420
Query: 322 NGGTCTHGINSFRCQCPAGFGGP--TCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379
C + S+RC C GF G TC + GQC G+ C C+ G+
Sbjct: 1421 INAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGF 1480
Query: 380 TGAA----CEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLS 435
T A+ C+ D+D+CS G+C +L G + C+C + ++ R + +
Sbjct: 1481 TPASDSRSCQ-DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADP 1539
Query: 436 APCHNGGTCVDADQGYVCECPEGFM----GLDCRERVPDDCECRNGGR------C----- 480
C NG CV+ Y C CP F G+ C + +C + G R C
Sbjct: 1540 INCVNG-LCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIG 1598
Query: 481 LGANTTLCQCPLG-FFGLLCEFEITAMPCNMN---TQCP--------------------- 515
+G + + C C LG +G CE T P N T CP
Sbjct: 1599 VGVSRSSCCCSLGKAWGNPCE---TCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQ 1655
Query: 516 ------DGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCF------NGGSCDAHDDSY 563
GG C+ GS+ C C + S D D CF G+C +Y
Sbjct: 1656 ELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNY 1715
Query: 564 TCECPRGFH----GKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHC---- 615
TC CP + G +C R C NG TC+ P+ T R C
Sbjct: 1716 TCICPPEYMQVNGGHNCMDMRKSFCYRS--YNGTTCEN-------ELPFNVTKRMCCCTY 1766
Query: 616 EIGKPDSCASGPC----------------------HNG-----------------GTCFH 636
+GK + PC H G G C +
Sbjct: 1767 NVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCIN 1826
Query: 637 YIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEV 696
IG ++C+CP GFS + CED D C G CQ
Sbjct: 1827 QIGSFRCECPTGFSYNDLLL--------------VCEDID-----ECSNG--DNLCQRNA 1865
Query: 697 DCGPPEEVKHATLRFNGTRLGAVALYACD--RGYSLSAPSRIRVCQPHGVWSEPPQCLEI 754
DC + + Y C+ G+ LS P+G + +CLEI
Sbjct: 1866 DC-----------------INSPGSYRCECAAGFKLS---------PNGACVDRNECLEI 1899
Query: 755 DECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE---LERDECRAHPCRNGGSCRNLPG 811
C H G C D Y C+C G++ + + ++ DEC HPC N G+C+N G
Sbjct: 1900 PNV----CSH-GLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGN-GTCKNTVG 1953
Query: 812 AYVCRCPAGFVGVHCE--TEVDACDSSPCQ--HGGRCESGGGAYLCVCPESF----FGYH 863
+Y C C GF H ++D C S Q GRC + G++ C+C E + G +
Sbjct: 1954 SYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKN 2013
Query: 864 C----ETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY--TGEDC 902
C E V+ P SP G C GS C C GY E+C
Sbjct: 2014 CIDTNECVALPGSCSP----GTCQNLEGSFRCICPPGYEVKSENC 2054
Score = 183 bits (464), Expect = 1e-45
Identities = 192/793 (24%), Positives = 280/793 (35%), Gaps = 197/793 (24%)
Query: 268 TTSVCLALRPCLNGGKCIDDCVTGNPSY---TCSCLSGFT--GRRCHLDVNECASQP--C 320
T S C P G+ C N + CS G T GR D+NECA P C
Sbjct: 724 TKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR----DINECALDPDIC 779
Query: 321 QNGGTCTHGINSFRCQCPAGF----GGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQ 376
NG C + S+RC C +G+ G C + G C+ GS C C
Sbjct: 780 ANG-ICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCP 838
Query: 377 AGYT----GAACEMDVDDCSPDPCLNGGSCVDLVGNYTC-------------LCAEPFKG 419
GY CE D+++C +PC+NG +C + +G++ C +C + KG
Sbjct: 839 PGYVFRTETETCE-DINECESNPCVNG-ACRNNLGSFNCECSPGSKLSSTGLICIDSLKG 896
Query: 420 L--------RCETGDHPVP---------DACLSAPCHN---------------------- 440
RCE + A +PC
Sbjct: 897 TCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDV 956
Query: 441 -----------GGTCVDADQGYVCECPEGF----MGLDCRERVPDDCECR-NGGRCLGA- 483
G CV++ + CECPEG G C + + C + + C+
Sbjct: 957 NECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPV 1016
Query: 484 ----NTTLCQCPLG-FFGLLCEFEITAMPCNMNTQCPDG--------------------- 517
C C +G +G CE T CP G
Sbjct: 1017 PGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINE 1076
Query: 518 ----------GYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPC------FNGGSCDAHDD 561
G C GS+ C C++ + D D C G C
Sbjct: 1077 CKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPG 1136
Query: 562 SYTCECPRGFHG-----KHCEKARPHLCSSGP--CRNGGTCKEAGGEYHCSCPYRFTGRH 614
S+ CEC G+ K+C C P CR GGTC G + C CP G
Sbjct: 1137 SFECECFEGYESGFMMMKNCMDIDE--CERNPLLCR-GGTCVNTEGSFQCDCP---LGHE 1190
Query: 615 CEIGKPD-------SCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCV 667
+ D S + C N G C + IG Y+C C PG+ + +
Sbjct: 1191 LSPSREDCVDINECSLSDNLCRN-GKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIM 1249
Query: 668 NGG---TCEDRDTDFFCHCQAGYM----GRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA 720
NGG C + + + C C GY GR C +C ++
Sbjct: 1250 NGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDI---------------- 1293
Query: 721 LYACDRGYSLSAPSRIRVCQPHGVWS--EPPQCLEIDEC--RSQPCLHGGSCQDRVAGYL 776
CD G + P R G + + C++++EC S C+ G C++ ++
Sbjct: 1294 ---CDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMF-GECENTKGSFI 1349
Query: 777 CLCSTGY---EGAHCELERDECR--AHPCRNGGSCRNLPGAYVCRCPAGFV--GVHCETE 829
C C GY +G + DEC AH C SC N+PG++ C C G++ G+ C +
Sbjct: 1350 CHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC-ID 1408
Query: 830 VDACDSS--PCQHGGRCESGGGAYLCVCPESFF--GYHCETVSDPCFSSPCGGRGYCLAS 885
+D C + C +C + G+Y C C E F G+ C V + + G CL
Sbjct: 1409 LDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNV 1468
Query: 886 NGSHSCTCKVGYT 898
G++ C C++G+T
Sbjct: 1469 PGAYRCECEMGFT 1481
Score = 179 bits (453), Expect = 2e-44
Identities = 184/669 (27%), Positives = 252/669 (37%), Gaps = 171/669 (25%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGF----TGRRCHLDVNECA-SQPCQNGGTCTHGINS 332
C NG C+ + S+ C C G+ TG RC +D +EC+ PC NG TCT+ I S
Sbjct: 2182 CSNG-----QCINTDGSFRCECPMGYNLDYTGVRC-VDTDECSIGNPCGNG-TCTNVIGS 2234
Query: 333 FRCQCPAGFG-GP--TCETAQSPCDTKECQHGG-----QCQVENGSAVCVCQAGYT---- 380
F C C GF GP CE D EC +C GS C C GY
Sbjct: 2235 FECNCNEGFEPGPMMNCE------DINECAQNPLLCAFRCMNTFGSYECTCPIGYALRED 2288
Query: 381 GAACEMDVDDCSP---DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPD-ACLSA 436
C+ D+D+C+ D G C +L+G + C+C P R G+ V + C +
Sbjct: 2289 QKMCK-DLDECAEGLHDCESRGMMCKNLIGTFMCIC--PPGMARRPDGEGCVDENECRTK 2345
Query: 437 P--CHNGGTCVDADQGYVCECPEGFM-------------GLDCRERVPDDCECRNGGRCL 481
P C NG CV+ Y CEC EGF GL E + C+ + R L
Sbjct: 2346 PGICENG-RCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNL 2404
Query: 482 GANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDG-GYCMEHGGSYLCVCHTDHNASHS 540
+ C +G CE CP G GY + D +
Sbjct: 2405 VTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDG---------RDIDECKV 2455
Query: 541 LPSPCDSDPCFNGGSCDAHDDSYTCECPRGF----HGKHCEKARPHLCSSGPCRNGGTCK 596
+P+ C + C N S+ C C G+ G C CS P CK
Sbjct: 2456 MPNLCTNGQCINTMG------SFRCFCKVGYTTDISGTSCIDLDE--CSQSPKPCNYICK 2507
Query: 597 EAGGEYHCSCPYRFT----GRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGR 652
G Y CSCP + G+ C+ D C + + C + +G + C CPPGF+
Sbjct: 2508 NTEGSYQCSCPRGYVLQEDGKTCK--DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQH 2565
Query: 653 HCE-IAPSPCFRSPCVNG--GTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATL 709
H I + C P + G G C++ F C CQ
Sbjct: 2566 HTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQ------------------------- 2600
Query: 710 RFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECR-SQPCLHGGSC 768
RG+SL A C ++DEC + C HG C
Sbjct: 2601 ----------------RGFSLDATGL--------------NCEDVDECDGNHRCQHG--C 2628
Query: 769 QDRVAGYLCLCSTGY----EGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGF--- 821
Q+ + GY C C GY + C ++ +EC SC N G+Y C CP+GF
Sbjct: 2629 QNILGGYRCGCPQGYIQHYQWNQC-VDENECSNPNACGSASCYNTLGSYKCACPSGFSFD 2687
Query: 822 -VGVHCETEVDACDSS--PCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGG 878
C +V+ C SS PC +G C + G YLC CP ++ G
Sbjct: 2688 QFSSACH-DVNECSSSKNPCNYG--CSNTEGGYLCGCPPGYYRV---------------G 2729
Query: 879 RGYCLASNG 887
+G+C++ G
Sbjct: 2730 QGHCVSGMG 2738
Score = 178 bits (452), Expect = 3e-44
Identities = 178/676 (26%), Positives = 268/676 (39%), Gaps = 139/676 (20%)
Query: 280 NGGKCIDD----CVTGNPSYTCSCLSGFTGRR----CHLDVNECASQPCQNGGTCTHGIN 331
NG +C D C T + CS F + C E PC+ C
Sbjct: 2092 NGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCE---LCPKDDE 2148
Query: 332 -SFRCQCPAGFGG-PTCETAQSPCDTKECQHG------GQCQVENGSAVCVCQAGY---- 379
+F+ CP G G P+ + D EC GQC +GS C C GY
Sbjct: 2149 VAFQDLCPYGHGTVPSLHDTRE--DVNECLESPGICSNGQCINTDGSFRCECPMGYNLDY 2206
Query: 380 TGAACEMDVDDCS-PDPCLNGGSCVDLVGNYTCLCAEPFKG---LRCETGDHPVPDACLS 435
TG C +D D+CS +PC NG +C +++G++ C C E F+ + CE + C
Sbjct: 2207 TGVRC-VDTDECSIGNPCGNG-TCTNVIGSFECNCNEGFEPGPMMNCEDINE-----CAQ 2259
Query: 436 APCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFF 495
P C++ Y C CP G+ + ++ D EC G + +C+ +G F
Sbjct: 2260 NPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTF 2319
Query: 496 GLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGS 555
+C P M + PDG C+ D N + P C++ C N
Sbjct: 2320 MCIC-------PPGMARR-PDGEGCV------------DENECRTKPGICENGRCVN--- 2356
Query: 556 CDAHDDSYTCECPRGFH----GKHCEKARPHLCSSGP----CRNGGTCKEAGGEYHCSCP 607
SY CEC GF G C R LC + C+ + + + C C
Sbjct: 2357 ---IIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCD 2413
Query: 608 Y-RFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCP--PGFS--GR---HCEIAPS 659
R G CE+ C GT +YK CP PG++ GR C++ P+
Sbjct: 2414 GGRGWGHQCEL----------CPLPGTA-----QYKKICPHGPGYTTDGRDIDECKVMPN 2458
Query: 660 PCFRSPCVNGGTCEDRDTDFFCHCQAGYM----GRRCQAEVDCGP-PEEVKHATLRFNGT 714
C C+N F C C+ GY G C +C P+ + G+
Sbjct: 2459 LCTNGQCIN------TMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGS 2512
Query: 715 RLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAG 774
+C RGY L + C ++DEC+++ C + + G
Sbjct: 2513 YQ-----CSCPRGYVLQEDGKT--------------CKDLDECQTKQHNCQFLCVNTLGG 2553
Query: 775 YLCLCSTGYEGAHCE-LERDECRAHP--CRNGGSCRNLPGAYVCRCPAGF----VGVHCE 827
+ C C G+ H ++ +EC + P C G C+N PG++ C C GF G++CE
Sbjct: 2554 FTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCE 2613
Query: 828 TEVDACDSSP-CQHGGRCESGGGAYLCVCPESFFGYH----CETVSDPCFSSPCGGRGYC 882
+VD CD + CQHG C++ G Y C CP+ + ++ C ++ + CG C
Sbjct: 2614 -DVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSAS-C 2669
Query: 883 LASNGSHSCTCKVGYT 898
+ GS+ C C G++
Sbjct: 2670 YNTLGSYKCACPSGFS 2685
Score = 176 bits (446), Expect = 1e-43
Identities = 189/718 (26%), Positives = 254/718 (35%), Gaps = 171/718 (23%)
Query: 281 GGKCIDDCVTGNPSYTCSCLSG---------FTGRRCHLDVNECASQPCQNGGTCTHG-- 329
G +C + G Y C G TGR + D+NEC + P G CT+G
Sbjct: 1034 GTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFP----GMCTYGKC 1089
Query: 330 ---INSFRCQCPAGFGGPTCETAQSPC-DTKECQ------HGGQCQVENGSAVCVCQAGY 379
I SF+C+C +GF + + C D EC+ G C GS C C GY
Sbjct: 1090 RNTIGSFKCRCNSGFA---LDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGY 1146
Query: 380 TGAACEM----DVDDCSPDPCL-NGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACL 434
M D+D+C +P L GG+CV+ G++ C C + + + L
Sbjct: 1147 ESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSL 1206
Query: 435 SAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECR--NGGRCLGANTTLCQCPL 492
S G CV+ Y C C G+ R+ D EC NGG C T C
Sbjct: 1207 SDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGG-C----DTQCTNSE 1261
Query: 493 GFFGLLCEFEITAMP----------CNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLP 542
G + C MP C N DGG C G Y C+C+ AS +
Sbjct: 1262 GSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMK 1321
Query: 543 SPCDSDPC-FNG-----GSCDAHDDSYTCECPRGFHGKH----CEKARPHLCSSGPCRNG 592
+ D + C N G C+ S+ C C G+ K C + C
Sbjct: 1322 TCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMH 1381
Query: 593 GTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGP--CHNGGTCFHYIGKYKCDCPPGFS 650
+C G + CSC + G + D C++G C C + G Y+C C GF+
Sbjct: 1382 ASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT 1441
Query: 651 GRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLR 710
G +G TC D D E ++ L
Sbjct: 1442 G----------------DGFTCSDVD-------------------------ECAENINLC 1460
Query: 711 FNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQD 770
NG L Y C+ + S R CQ +IDEC Q G+C +
Sbjct: 1461 ENGQCLNVPGAYRCECEMGFTPASDSRSCQ------------DIDECSFQNICVFGTCNN 1508
Query: 771 RVAGYLCLCSTGYE----GAHCELERDECRAHP--CRNGGSCRNLPGAYVCRCPAGF--- 821
+ C+C GYE G +C + DEC A P C N G C N PG Y C CP F
Sbjct: 1509 LPGMFHCICDDGYELDRTGGNC-TDIDEC-ADPINCVN-GLCVNTPGRYECNCPPDFQLN 1565
Query: 822 ---VG--------------------VHCETEV-------DACDSSPCQHGGRCES----G 847
VG + C TE+ C S G CE+
Sbjct: 1566 PTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVN 1625
Query: 848 GGAYLCVCPESFFGYHCETVS------DPCFSSP--CGGRGYCLASNGSHSCTCKVGY 897
Y +CP G+ ++ D C P C G G C+ + GS C C GY
Sbjct: 1626 STEYYTLCPGG-EGFRPNPITIILEDIDECQELPGLCQG-GNCINTFGSFQCECPQGY 1681
Score = 167 bits (422), Expect = 9e-41
Identities = 194/752 (25%), Positives = 283/752 (37%), Gaps = 167/752 (22%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHL---DVNECASQP--CQNGGTCTHGINS 332
C NG C+ S+ C C +GF+ L D++EC++ CQ C + S
Sbjct: 1819 CANGV-----CINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGS 1873
Query: 333 FRCQCPAGF----GGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACE--- 385
+RC+C AGF G + + C HG C GS C+C G+ + +
Sbjct: 1874 YRCECAAGFKLSPNGACVDRNECLEIPNVCSHG-LCVDLQGSYQCICHNGFKASQDQTMC 1932
Query: 386 MDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLS---APCHNGG 442
MDVD+C PC NG +C + VG+Y CLC F+ D D C S C NG
Sbjct: 1933 MDVDECERHPCGNG-TCKNTVGSYNCLCYPGFE--LTHNNDCLDIDECSSFFGQVCRNG- 1988
Query: 443 TCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLG----ANTTLCQCPLGFFGLL 498
C + + C C EG+ E PD C + C+ + CQ G F +
Sbjct: 1989 RCFNEIGSFKCLCNEGY------ELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCI 2042
Query: 499 CE--FEITAMPCNMNTQCPDG------GYCMEHGGSYLCVCHTD---------------- 534
C +E+ + C +C + G C G + C+C
Sbjct: 2043 CPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQS 2102
Query: 535 ------HNASHSLPSPCDS----------------DPCFNGGSCDAHDD-SYTCECPRGF 571
N S+P ++ DPC C D+ ++ CP G
Sbjct: 2103 FCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPC---ELCPKDDEVAFQDLCPYG- 2158
Query: 572 HGK----HCEKARPHLC--SSGPCRNGGTCKEAGGEYHCSCPYRF----TGRHCEIGKPD 621
HG H + + C S G C NG C G + C CP + TG C D
Sbjct: 2159 HGTVPSLHDTREDVNECLESPGICSNG-QCINTDGSFRCECPMGYNLDYTGVRCV--DTD 2215
Query: 622 SCASG-PCHNGGTCFHYIGKYKCDCPPGFSG---RHCEIAPSPCFRSPCVNGGTCEDRDT 677
C+ G PC NG TC + IG ++C+C GF +CE + C ++P + C +
Sbjct: 2216 ECSIGNPCGNG-TCTNVIGSFECNCNEGFEPGPMMNCEDI-NECAQNPLLCAFRCMNTFG 2273
Query: 678 DFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACD-RGYSLSAPSRI 736
+ C C GY R Q C +E A L+ C+ RG
Sbjct: 2274 SYECTCPIGYALREDQKM--CKDLDEC-------------AEGLHDCESRGMMCKNLIGT 2318
Query: 737 RVCQ-PHGVWSEPPQ--CLEIDECRSQPCL-HGGSCQDRVAGYLCLCSTGYE----GAHC 788
+C P G+ P C++ +ECR++P + G C + + Y C C+ G++ G C
Sbjct: 2319 FMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTEC 2378
Query: 789 ELERD-----ECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVH-CET-------------- 828
R E C+ S RNL C C G H CE
Sbjct: 2379 LDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICP 2438
Query: 829 ----------EVDACDSSP--CQHGGRCESGGGAYLCVCPESFF----GYHCETVSDPCF 872
++D C P C +G +C + G++ C C + G C + D C
Sbjct: 2439 HGPGYTTDGRDIDECKVMPNLCTNG-QCINTMGSFRCFCKVGYTTDISGTSCIDL-DECS 2496
Query: 873 SSPCGGRGYCLASNGSHSCTCKVGYTGEDCAK 904
SP C + GS+ C+C GY ++ K
Sbjct: 2497 QSPKPCNYICKNTEGSYQCSCPRGYVLQEDGK 2528
Score = 161 bits (408), Expect = 4e-39
Identities = 192/707 (27%), Positives = 264/707 (37%), Gaps = 178/707 (25%)
Query: 268 TTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGF-----TGRRCHLDVNECASQP--C 320
T VC C G+ P+ C GF TG C DV+EC + P C
Sbjct: 230 TGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGA-CQ-DVDECQAIPGIC 287
Query: 321 QNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQ------HGGQCQVENGSAVCV 374
Q GG C + + SF C+CPAG ET Q D EC G+C GS CV
Sbjct: 288 Q-GGNCINTVGSFECRCPAGH--KQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCV 344
Query: 375 CQAGYTGAACEMDVDDCSPDPCLNG---GSCV-DLVGNYTCL--CAEPFKGLRCETGDHP 428
C GY + D C +G G C +L G T + C EP RC G
Sbjct: 345 CPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG---RC-WGIGT 400
Query: 429 VPDACLS-----------------------------------APCHNGGTCVDADQGYVC 453
+P+AC AP NG G++
Sbjct: 401 IPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFI- 459
Query: 454 ECPEG--------------------FMGLDCRERVPDDCE-----CRNGGRCLGANTTL- 487
P G GL + D C+ C NG RC+ ++
Sbjct: 460 PIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNG-RCIPTVSSYR 518
Query: 488 CQCPLGFF-----GLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLP 542
C+C +G+ + E T+ PC G C+ GSY C CH + +
Sbjct: 519 CECNMGYKQDANGDCIDVDECTSNPCT-------NGDCVNTPGSYYCKCHAGFQRTPTKQ 571
Query: 543 SPCDSDPCF-NG-----GSCDAHDDSYTCECPRGFH----GKHC----EKARPHLCSSGP 588
+ D D C NG G C D S+ C C GF GK+C E ++C +G
Sbjct: 572 ACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGM 631
Query: 589 CRNGGTCKEAGGEYHCSCPYRFT----GRHCEIGKPDSCAS-GPCHNGGTCFHYIGKYKC 643
C N G + C C F GR+C D C + G C NG C + G ++C
Sbjct: 632 CIN------EDGSFKCICKPGFVLAPNGRYCT--DVDECQTPGICMNGH-CINSEGSFRC 682
Query: 644 DCPPGFS-GRHCEIAPSPCFRSPCVNG---GTCEDRDTDFFCHCQAGYMGRRCQAEVDCG 699
DCPPG + G + RS C G G C + G ++E C
Sbjct: 683 DCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCV-----------RPFPGAVTKSECCCA 731
Query: 700 PPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRS 759
P+ + + A C G ++ R +I+EC
Sbjct: 732 NPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR-----------------DINECAL 774
Query: 760 QPCL-HGGSCQDRVAGYLCLCSTGYE----GAHCELERDECRAHP--CRNGGSCRNLPGA 812
P + G C++ Y C C++GYE G +C ++ DEC + C NG CRN PG+
Sbjct: 775 DPDICANGICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNG-LCRNTPGS 832
Query: 813 YVCRCPAGFVGVHCETE----VDACDSSPCQHGGRCESGGGAYLCVC 855
Y C CP G+V ETE ++ C+S+PC +G C + G++ C C
Sbjct: 833 YSCTCPPGYV-FRTETETCEDINECESNPCVNGA-CRNNLGSFNCEC 877
Score = 152 bits (384), Expect = 2e-36
Identities = 197/766 (25%), Positives = 292/766 (38%), Gaps = 176/766 (22%)
Query: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGF----TGRRCHLDVNECASQPCQNG-GTC 326
C L GG CI+ S+ C C G+ R C D++EC + P G GTC
Sbjct: 1654 CQELPGLCQGGNCINTF----GSFQCECPQGYYLSEDTRICE-DIDECFAHPGVCGPGTC 1708
Query: 327 THGINSFRCQCPA---------------------GFGGPTCE-------TAQSPCDT--- 355
+ + ++ C CP + G TCE T + C T
Sbjct: 1709 YNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNV 1768
Query: 356 -----KECQHGGQCQVENGSAVCVCQAGYT-----GAACEMDVDDCSPDP--CLNGGSCV 403
K C+ + +C G+T G A +D+D+C P C NG C+
Sbjct: 1769 GKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKA--VDIDECKEIPGICANG-VCI 1825
Query: 404 DLVGNYTCLCAEPFKG----LRCETGDHPVPDACLSAP--CHNGGTCVDADQGYVCECPE 457
+ +G++ C C F L CE D C + C C+++ Y CEC
Sbjct: 1826 NQIGSFRCECPTGFSYNDLLLVCEDIDE-----CSNGDNLCQRNADCINSPGSYRCECAA 1880
Query: 458 GFM---------GLDCRERVPDDCECRNGGRCLGANTTL-CQCPLGFFGLLCEFEITAMP 507
GF +C E +P+ C + G C+ + C C GF + + M
Sbjct: 1881 GFKLSPNGACVDRNECLE-IPNVC---SHGLCVDLQGSYQCICHNGFKA--SQDQTMCMD 1934
Query: 508 CNMNTQCPDG-GYCMEHGGSYLCVCHTDHNASHSLPSPC-DSDPCFN-------GGSCDA 558
+ + P G G C GSY C+C+ +H+ + C D D C + G C
Sbjct: 1935 VDECERHPCGNGTCKNTVGSYNCLCYPGFELTHN--NDCLDIDECSSFFGQVCRNGRCFN 1992
Query: 559 HDDSYTCECPRGFH----GKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCP--YRFTG 612
S+ C C G+ GK+C + G C + GTC+ G + C CP Y
Sbjct: 1993 EIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSC-SPGTCQNLEGSFRCICPPGYEVKS 2051
Query: 613 RHC-EIGK----PDSCASGPCHNGGTCFHYIGKYKCDCPPGF----SGRHC-EIAPSPCF 662
+C +I + P+ C G C N G ++C CPPGF +GR C + S CF
Sbjct: 2052 ENCIDINECDEDPNICLFGSCTNTP------GGFQCLCPPGFVLSDNGRRCFDTRQSFCF 2105
Query: 663 RSPCVNGGTCED----RDTDFFCHCQA----GYMGRRCQAEVDCGPPEEVK--------H 706
+ G C T C C G+ G C+ C +EV H
Sbjct: 2106 TN--FENGKCSVPKAFNTTKAKCCCSKMPGEGW-GDPCEL---CPKDDEVAFQDLCPYGH 2159
Query: 707 ATL-RFNGTRLGAVALYA----CDRGYSLSAPSRIRVCQPHGVWSEPP--QCLEIDECR- 758
T+ + TR C G ++ R P G + +C++ DEC
Sbjct: 2160 GTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI 2219
Query: 759 SQPCLHGGSCQDRVAGYLCLCSTGYEGA---HCELERDECRAHPCRNGGSCRNLPGAYVC 815
PC G+C + + + C C+ G+E +CE + +EC +P C N G+Y C
Sbjct: 2220 GNPC-GNGTCTNVIGSFECNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYEC 2277
Query: 816 RCPAGFVGVHCETEVDAC-DSSPCQHGGR-CESGG-------GAYLCVCPESFF----GY 862
CP G+ + C D C G CES G G ++C+CP G
Sbjct: 2278 TCPIGYA---LREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGE 2334
Query: 863 HCETVSDPCFSSP--CGGRGYCLASNGSHSCTCKVGY----TGEDC 902
C ++ C + P C G C+ GS+ C C G+ +G +C
Sbjct: 2335 GCVDENE-CRTKPGICEN-GRCVNIIGSYRCECNEGFQSSSSGTEC 2378
Score = 149 bits (375), Expect = 2e-35
Identities = 155/582 (26%), Positives = 215/582 (36%), Gaps = 124/582 (21%)
Query: 399 GGSCVDLVGNYTC---LCAEPFKGLRCETGDHPVPDAC-------LSAPCHNGGTCVDAD 448
G C+ + +C C+ P C + C S C NGGTC D
Sbjct: 107 GNQCIVPICRNSCGDGFCSRPNM---CTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDH 163
Query: 449 QGYVCECPEGFMGLDCRERVPDDCE--CRNGGRCLGANTTLCQCPLGFFGLLCEFEITAM 506
C+C +G++G C + V CE C+NGGRC+G N C C GF G CE +
Sbjct: 164 ----CQCQKGYIGTYCGQPV---CENGCQNGGRCIGPNR--CACVYGFTGPQCERDYRTG 214
Query: 507 PC--NMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLP-SPCDSDPCFNG-------GSC 556
PC +N Q G LC H P PC G G+C
Sbjct: 215 PCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGAC 274
Query: 557 DAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCP----YRFTG 612
D EC +A P +C GG C G + C CP T
Sbjct: 275 QDVD-----EC----------QAIPGIC------QGGNCINTVGSFECRCPAGHKQSETT 313
Query: 613 RHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGF----SGRHC-EIAPSPCFRSPCV 667
+ CE S G C G C + +G Y C CP G+ G C + CF S V
Sbjct: 314 QKCEDIDECSIIPGICET-GECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCF-SGLV 371
Query: 668 NGGTCED---RDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYAC 724
NG ++ R T C C+ G C ++ L +G +G + A
Sbjct: 372 NGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAG 431
Query: 725 DR----------------GYSLSAPSRIRVCQPHGVWSEP-------------------- 748
R GY I + P G P
Sbjct: 432 SRPGGTGGNGFAPSGNGNGYGPGGTGFIPI--PGGNGFSPGVGGAGVGAGGQGPIITGLT 489
Query: 749 --PQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE---GAHCELERDECRAHPCRNG 803
Q ++I + + CL+ G C V+ Y C C+ GY+ C ++ DEC ++PC N
Sbjct: 490 ILNQTIDICKHHANLCLN-GRCIPTVSSYRCECNMGYKQDANGDC-IDVDECTSNPCTN- 546
Query: 804 GSCRNLPGAYVCRCPAGFVGVHCE---TEVDAC-DSSPCQHGGRCESGGGAYLCVCPESF 859
G C N PG+Y C+C AGF + ++D C + GRC + G++ C+C F
Sbjct: 547 GDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGF 606
Query: 860 ----FGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 897
G +C D C ++ G C+ +GS C CK G+
Sbjct: 607 ELTTDGKNC-VDHDECTTTNMCLNGMCINEDGSFKCICKPGF 647
Score = 148 bits (373), Expect = 4e-35
Identities = 176/674 (26%), Positives = 237/674 (35%), Gaps = 174/674 (25%)
Query: 297 CSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTK 356
C+C SG C + S C NGGTC CQC G+ G C Q C+
Sbjct: 130 CTCSSGQISSTCGSKSIQQCSVRCMNGGTCADD----HCQCQKGYIGTYC--GQPVCE-N 182
Query: 357 ECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPC---LNGGSCVDLVGNYTCLC 413
CQ+GG+C G C C G+TG CE D PC +N C + C
Sbjct: 183 GCQNGGRC---IGPNRCACVYGFTGPQCERDY---RTGPCFTQVNNQMCQGQLTGIVCT- 235
Query: 414 AEPFKGLRCET----GDHPVPDACLS--APCHNG-------GTCVDADQGYVCECPEGFM 460
K L C T HP + C + PC G G C D D EC
Sbjct: 236 ----KTLCCATIGRAWGHPC-EMCPAQPQPCRRGFIPNIRTGACQDVD-----EC----- 280
Query: 461 GLDCRERVPDDCECRNGGRCLG-ANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCP---- 515
+ +P C+ GG C+ + C+CP G + T C +C
Sbjct: 281 -----QAIPGICQ---GGNCINTVGSFECRCPAGH-----KQSETTQKCEDIDECSIIPG 327
Query: 516 --DGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHG 573
+ G C GSY CVC + S D C D T C G
Sbjct: 328 ICETGECSNTVGSYFCVCPRGYVTS------TDGSRCI---------DQRTGMCFSGLVN 372
Query: 574 KHCEKARPH-------LCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEI--------G 618
C + P C G C GT EA CP R + + + G
Sbjct: 373 GRCAQELPGRMTKMQCCCEPGRCWGIGTIPEA-------CPVRGSEEYRRLCMDGLPMGG 425
Query: 619 KPDSCASGPCHNGGTCFHYIGKYKCDCP--------PGFSGRHCEIAPSPC---FRSPCV 667
P S S P GG F G P PG +G + + + P +
Sbjct: 426 IPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPII 485
Query: 668 NGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACD-- 725
G T ++ D H HA L NG + V+ Y C+
Sbjct: 486 TGLTILNQTIDICKH-----------------------HANLCLNGRCIPTVSSYRCECN 522
Query: 726 RGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEG 785
GY A C+++DEC S PC + G C + Y C C G++
Sbjct: 523 MGYKQDANG---------------DCIDVDECTSNPCTN-GDCVNTPGSYYCKCHAGFQR 566
Query: 786 AHCE---LERDECRAHP--CRNGGSCRNLPGAYVCRCPAGFV----GVHCETEVDACDSS 836
+ ++ DEC + C+N G C N G++ C C AGF G +C + D C ++
Sbjct: 567 TPTKQACIDIDECIQNGVLCKN-GRCVNTDGSFQCICNAGFELTTDGKNC-VDHDECTTT 624
Query: 837 PCQHGGRCESGGGAYLCVCPESFF----GYHCETVSDPCFSSPCGGRGYCLASNGSHSCT 892
G C + G++ C+C F G +C V D C + G+C+ S GS C
Sbjct: 625 NMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDV-DECQTPGICMNGHCINSEGSFRCD 683
Query: 893 C----KVGYTGEDC 902
C VG G C
Sbjct: 684 CPPGLAVGMDGRVC 697
Score = 144 bits (362), Expect = 8e-34
Identities = 176/698 (25%), Positives = 252/698 (36%), Gaps = 139/698 (19%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
CG + ++R C+NGG C DD C C G+ G C V E CQNGG
Sbjct: 141 CGSKSIQQCSVR-CMNGGTCADD--------HCQCQKGYIGTYCGQPVCE---NGCQNGG 188
Query: 325 TCTHGINSFRCQCPAGFGGPTCET--AQSPCDTKECQHGGQCQVENGSAVCV-------- 374
C I RC C GF GP CE PC T+ + CQ + VC
Sbjct: 189 RC---IGPNRCACVYGFTGPQCERDYRTGPCFTQ--VNNQMCQGQLTGIVCTKTLCCATI 243
Query: 375 -----------------CQAGY-----TGAACEMDVDDCSPDPCL-NGGSCVDLVGNYTC 411
C+ G+ TGA DVD+C P + GG+C++ VG++ C
Sbjct: 244 GRAWGHPCEMCPAQPQPCRRGFIPNIRTGAC--QDVDECQAIPGICQGGNCINTVGSFEC 301
Query: 412 LCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD 471
C K + + + G C + Y C CP G++
Sbjct: 302 RCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYV----------- 350
Query: 472 CECRNGGRCLGANTTLCQCPLGFFGLL---CEFEITAMPCNMNTQCPDG---------GY 519
+G RC+ T +C F GL+ C E+ M C G
Sbjct: 351 -TSTDGSRCIDQRTGMC-----FSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEA 404
Query: 520 CMEHGG-SYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEK 578
C G Y +C D +P S P GG+ A + P G
Sbjct: 405 CPVRGSEEYRRLC-MDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPG 463
Query: 579 ARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYI 638
S G GG AGG+ + +I K + C N G C +
Sbjct: 464 GNGF--SPGV---GGAGVGAGGQGPIITGLTILNQTIDICKHH---ANLCLN-GRCIPTV 514
Query: 639 GKYKCDCPPGF---SGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAE 695
Y+C+C G+ + C I C +PC N G C + ++C C AG+ +R +
Sbjct: 515 SSYRCECNMGYKQDANGDC-IDVDECTSNPCTN-GDCVNTPGSYYCKCHAGF--QRTPTK 570
Query: 696 VDCGPPEE-VKHATLRFNGTRLGAVALY--ACDRGYSLSAPSRIRVCQPHGVWSEPPQCL 752
C +E +++ L NG + + C+ G+ L+ + C+
Sbjct: 571 QACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGK--------------NCV 616
Query: 753 EIDECRSQPCLHGGSCQDRVAGYLCLCSTGY----EGAHCELERDECRAHPCRNGGSCRN 808
+ DEC + G C + + C+C G+ G +C + DEC+ G C N
Sbjct: 617 DHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGICMNGHCIN 675
Query: 809 LPGAYVCRCPAGF-VGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETV 867
G++ C CP G VG+ VD S C GG VC F G T
Sbjct: 676 SEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCY--------GGIKKGVCVRPFPG--AVTK 725
Query: 868 SDPCFSSPCGGRGY----CLASNGSH---SCTCKVGYT 898
S+ C ++P G G C A N + C+ VG T
Sbjct: 726 SECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGIT 763
Score = 91.7 bits (226), Expect = 5e-18
Identities = 96/375 (25%), Positives = 143/375 (38%), Gaps = 65/375 (17%)
Query: 550 CFNGGSCDAHDDSYTCECPRGF-HGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPY 608
C NG C SY CEC G+ + + C+S PC NG C G Y+C C
Sbjct: 505 CLNG-RCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGD-CVNTPGSYYCKCHA 562
Query: 609 RF----TGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFS----GRHCEIAPSP 660
F T + C I + +G G C + G ++C C GF G++C
Sbjct: 563 GFQRTPTKQAC-IDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDEC 621
Query: 661 CFRSPCVNGGTCEDRDTDFFCHCQAGYM----GRRCQAEVDCGPPEEVKHATLRFNGTRL 716
+ C+NG C + D F C C+ G++ GR C +C P + NG +
Sbjct: 622 TTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPG------ICMNGHCI 674
Query: 717 GAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHG---GSCQDRVA 773
+ + CD L+ RVC +D C G G C
Sbjct: 675 NSEGSFRCDCPPGLAVGMDGRVC--------------VDTHMRSTCYGGIKKGVCVRPFP 720
Query: 774 GYL----CLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCE-T 828
G + C C+ G + C+ P +N L C +G VG+ +
Sbjct: 721 GAVTKSECCCANPDYGFG-----EPCQPCPAKNSAEFHGL-------CSSG-VGITVDGR 767
Query: 829 EVDACDSSP--CQHGGRCESGGGAYLCVCPESF----FGYHCETVSDPCFSSPCGGRGYC 882
+++ C P C +G CE+ G+Y C C + G +C + + + G C
Sbjct: 768 DINECALDPDICANG-ICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLC 826
Query: 883 LASNGSHSCTCKVGY 897
+ GS+SCTC GY
Sbjct: 827 RNTPGSYSCTCPPGY 841
Score = 89.7 bits (221), Expect = 2e-17
Identities = 98/350 (28%), Positives = 128/350 (36%), Gaps = 94/350 (26%)
Query: 595 CKEAGGEYHCSCPYRFTGRHCEIGKPDS-CASGP-------CHNGGTCFHYIGKYKCDCP 646
C+ + G+ CS P T C G+ S C S C NGGTC C C
Sbjct: 115 CRNSCGDGFCSRPNMCT---CSSGQISSTCGSKSIQQCSVRCMNGGTC----ADDHCQCQ 167
Query: 647 PGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKH 706
G+ G +C P + C NGG C + C C G+ G +C+ + GP
Sbjct: 168 KGYIGTYCG---QPVCENGCQNGGRCIGPNR---CACVYGFTGPQCERDYRTGPC----- 216
Query: 707 ATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHG- 765
T N G + C + + R W P E+ + QPC G
Sbjct: 217 FTQVNNQMCQGQLTGIVCTKTLCCATIGR--------AWGHP---CEMCPAQPQPCRRGF 265
Query: 766 ------GSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP--CRNGGSCRNLPGAYVCRC 817
G+CQD DEC+A P C+ GG+C N G++ CRC
Sbjct: 266 IPNIRTGACQDV---------------------DECQAIPGICQ-GGNCINTVGSFECRC 303
Query: 818 PAGF----VGVHCETEVDACDSSP--CQHGGRCESGGGAYLCVCPESFFGYHCETVSDPC 871
PAG CE ++D C P C+ G C + G+Y CVCP GY T C
Sbjct: 304 PAGHKQSETTQKCE-DIDECSIIPGICETG-ECSNTVGSYFCVCPR---GYVTSTDGSRC 358
Query: 872 FSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTALKMERVEESG 921
G C G CA+EL P KM+ E G
Sbjct: 359 IDQRTG--------------MCFSGLVNGRCAQEL-PGRMTKMQCCCEPG 393
Score = 34.3 bits (77), Expect = 0.87
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV 1349
C+ NPC NG CV ++ C C GF+ + ACI +
Sbjct: 539 CTSNPCTNGD-CVNTPGSYYCKCHAGFQRTPTKQACIDI 576
Score = 33.9 bits (76), Expect = 1.1
Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Query: 1313 ENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
EN CQNGG C+ + C C GF G +CE
Sbjct: 181 ENGCQNGGRCI---GPNRCACVYGFTGPQCE 208
Score = 33.5 bits (75), Expect = 1.5
Identities = 15/37 (40%), Positives = 18/37 (48%), Gaps = 1/37 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACI 1347
C NPC NG C + +C+C PG K L CI
Sbjct: 856 CESNPCVNGA-CRNNLGSFNCECSPGSKLSSTGLICI 891
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 205 bits (521), Expect = 3e-52
Identities = 109/297 (36%), Positives = 147/297 (49%), Gaps = 26/297 (8%)
Query: 297 CSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDT- 355
C C G+ GR C +EC P GTC ++C C G+GG C + C
Sbjct: 243 CKCRVGWQGRYC----DECIRYPGCLHGTCQQ---PWQCNCQEGWGGLFCNQDLNYCTHH 295
Query: 356 KECQHGGQC-QVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCA 414
K C++G C GS C C+ GYTGA CE+ +D+C P PC NGGSC DL +Y+C C
Sbjct: 296 KPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCP 355
Query: 415 EPFKGLRCETGDHPVPDACLSAPCHNGGTCVDA-DQGYVCECPEGFMGLDCRERVPDDCE 473
F G CE C PC NGG C D+ D GY C CP G+ G +C +++ D C
Sbjct: 356 PGFYGKICELSAM----TCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI-DYCS 410
Query: 474 ---CRNGGRCLG-ANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC 529
C NG +C+ + LC+C GF G C+ + ++ C +GG C + + C
Sbjct: 411 SSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCA---SSPCANGGTCRDGVNDFSC 467
Query: 530 VC---HTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHL 583
C +T N S + S C+ PC NG +C Y CEC RG+ G +C+ P L
Sbjct: 468 TCPPGYTGRNCSAPV-SRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPEL 523
Score = 203 bits (517), Expect = 8e-52
Identities = 98/247 (39%), Positives = 126/247 (51%), Gaps = 11/247 (4%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
C + C +PC NG C + TG SYTCSC G+TG C L ++EC PC+NGG
Sbjct: 285 CNQDLNYCTHHKPCKNGATCTN---TGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG 341
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQC-QVENGSAVCVCQAGYTGAA 383
+CT NS+ C CP GF G CE + C C +GG+C +G C C GY+G
Sbjct: 342 SCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFN 401
Query: 384 CEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGT 443
CE +D CS PC NG CVDL Y C C F G C+ D C S+PC NGGT
Sbjct: 402 CEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN----VDDCASSPCANGGT 457
Query: 444 CVDADQGYVCECPEGFMGLDCRERVP--DDCECRNGGRC-LGANTTLCQCPLGFFGLLCE 500
C D + C CP G+ G +C V + C NG C + +C+C G+ G C+
Sbjct: 458 CRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQ 517
Query: 501 FEITAMP 507
F + +P
Sbjct: 518 FLLPELP 524
Score = 199 bits (507), Expect = 1e-50
Identities = 130/358 (36%), Positives = 160/358 (44%), Gaps = 35/358 (9%)
Query: 397 LNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG--TCVDADQGYVCE 454
L+ DL +Y +C E + G C P DA C G C +G C
Sbjct: 163 LHSSGRTDLKYSYRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCT 222
Query: 455 CPEGFMGLDCRERV---PDDCECRNG--GR----------CLGANTTL---CQCPLGFFG 496
P G D + P +C+CR G GR CL C C G+ G
Sbjct: 223 EPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGG 282
Query: 497 LLCEFEITAMPCNMNTQCPDGGYCMEHG-GSYLCVCHTDHN-ASHSLP-SPCDSDPCFNG 553
L C ++ C + C +G C G GSY C C + A+ L CD PC NG
Sbjct: 283 LFCNQDLNY--CTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNG 340
Query: 554 GSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEA-GGEYHCSCPYRFTG 612
GSC ++SY+C CP GF+GK CE + C+ GPC NGG C ++ G Y C CP ++G
Sbjct: 341 GSCTDLENSYSCTCPPGFYGKICELS-AMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSG 399
Query: 613 RHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTC 672
+CE K D C+S PC NG C Y C C GFSGRHC+ C SPC NGGTC
Sbjct: 400 FNCE-KKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTC 458
Query: 673 EDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGT--RLGAVALYACDRGY 728
D DF C C GY GR C A P +HA T G + C RGY
Sbjct: 459 RDGVNDFSCTCPPGYTGRNCSA-----PVSRCEHAPCHNGATCHERGHRYVCECARGY 511
Score = 194 bits (492), Expect = 7e-49
Identities = 103/282 (36%), Positives = 133/282 (47%), Gaps = 23/282 (8%)
Query: 257 DAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECA 316
+ + RVG G C+ CL+G T + C+C G+ G C+ D+N C
Sbjct: 242 ECKCRVGWQGRYCDECIRYPGCLHG--------TCQQPWQCNCQEGWGGLFCNQDLNYCT 293
Query: 317 -SQPCQNGGTCTH-GINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCV 374
+PC+NG TCT+ G S+ C C G+ G TCE CD C++GG C S C
Sbjct: 294 HHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCT 353
Query: 375 CQAGYTGAACEMDVDDCSPDPCLNGGSCVDLV-GNYTCLCAEPFKGLRCETGDHPVPDAC 433
C G+ G CE+ C+ PC NGG C D G Y+C C + G CE D C
Sbjct: 354 CPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCE----KKIDYC 409
Query: 434 LSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCL-GANTTLCQ 489
S+PC NG CVD Y+C C GF G C + V DDC C NGG C G N C
Sbjct: 410 SSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNV-DDCASSPCANGGTCRDGVNDFSCT 468
Query: 490 CPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC 531
CP G+ G C ++ + C +G C E G Y+C C
Sbjct: 469 CPPGYTGRNCSAPVSRCE---HAPCHNGATCHERGHRYVCEC 507
Score = 190 bits (483), Expect = 7e-48
Identities = 120/390 (30%), Positives = 163/390 (41%), Gaps = 55/390 (14%)
Query: 556 CDAHDDSY---TCE------CPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSC 606
C DD++ TC C G+ G +C + +C G G C + G C C
Sbjct: 192 CRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEP---ICLPGCDEQHGFCDKPG---ECKC 245
Query: 607 PYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPC-FRSP 665
+ GR+C D C P GTC ++C+C G+ G C + C P
Sbjct: 246 RVGWQGRYC-----DECIRYPGCLHGTCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKP 297
Query: 666 CVNGGTCEDRDT-DFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYAC 724
C NG TC + + C C+ GY G C+ +D P K+ +
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG-----------SCTDL 346
Query: 725 DRGYSLSAPSRI--RVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRV-AGYLCLCST 781
+ YS + P ++C+ L C PC +GG C D GY C C
Sbjct: 347 ENSYSCTCPPGFYGKICE-----------LSAMTCADGPCFNGGRCSDSPDGGYSCRCPV 395
Query: 782 GYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHG 841
GY G +CE + D C + PC NG C +L AY+CRC AGF G HC+ VD C SSPC +G
Sbjct: 396 GYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANG 455
Query: 842 GRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGED 901
G C G + C CP + G +C C +PC C + C C GY G +
Sbjct: 456 GTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPN 515
Query: 902 C---AKELFPPTAL--KMERVEESGVSISW 926
C EL P A+ E++E G W
Sbjct: 516 CQFLLPELPPGPAVVDLTEKLEGQGGPFPW 545
Score = 115 bits (289), Expect = 2e-25
Identities = 49/121 (40%), Positives = 64/121 (52%), Gaps = 4/121 (3%)
Query: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
PC NG KC+D +Y C C +GF+GR C +V++CAS PC NGGTC G+N F C
Sbjct: 413 PCSNGAKCVDL----GDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCT 468
Query: 337 CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPC 396
CP G+ G C S C+ C +G C VC C GY G C+ + + P P
Sbjct: 469 CPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGPA 528
Query: 397 L 397
+
Sbjct: 529 V 529
Score = 51.2 bits (121), Expect = 7e-06
Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 17/77 (22%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
+C+ +PC NGGTC G + SC C PG+ GR C S P +R + P G
Sbjct: 446 DCASSPCANGGTCRDGVNDFSCTCPPGYTGRNC-------SAPVSR----CEHAPCHNGA 494
Query: 1370 VCHHVYKRVYRVHQDIC 1386
CH R H+ +C
Sbjct: 495 TCHE------RGHRYVC 505
Score = 48.5 bits (114), Expect = 4e-05
Identities = 19/44 (43%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C +PC+NGG+C +++SC C PGF G+ CEL+ + PC
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPC 375
Score = 45.4 bits (106), Expect = 4e-04
Identities = 17/33 (51%), Positives = 20/33 (60%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
CS +PC NG CV DA+ C C GF GR C+
Sbjct: 409 CSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCD 441
Score = 39.7 bits (91), Expect = 0.021
Identities = 15/31 (48%), Positives = 20/31 (64%), Gaps = 1/31 (3%)
Query: 1315 PCQNGGTCV-PGADAHSCDCGPGFKGRRCEL 1344
PC+NG TC G +++C C PG+ G CEL
Sbjct: 297 PCKNGATCTNTGQGSYTCSCRPGYTGATCEL 327
Score = 37.4 bits (85), Expect = 0.10
Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 1311 CSENPCQNGGTCVPGAD-AHSCDCGPGFKGRRCE 1343
C++ PC NGG C D +SC C G+ G CE
Sbjct: 370 CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCE 403
Score = 36.2 bits (82), Expect = 0.23
Identities = 13/47 (27%), Positives = 20/47 (42%)
Query: 1297 PEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
P + ++ C PC NG TC + C+C G+ G C+
Sbjct: 471 PGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQ 517
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 201 bits (512), Expect = 3e-51
Identities = 178/597 (29%), Positives = 242/597 (40%), Gaps = 104/597 (17%)
Query: 288 CVTGNPSYTCSCLSGF----TGRRCHLDVNEC--ASQPCQNGGTCTHGINSFRCQCPAGF 341
C++ YTC+C SGF G RC +DV+EC PC G C + SFRC C GF
Sbjct: 494 CISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGF 551
Query: 342 -GGP---------TCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYT----GAACEMD 387
GP C PCD G+C+ GS +CVC AGY GA+C+ D
Sbjct: 552 RAGPRAAECLDVDECHRVPPPCDL------GRCENTPGSFLCVCPAGYQAAPHGASCQ-D 604
Query: 388 VDDCSPDPCLNG-GSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVD 446
VD+C+ P L G G+C +L G++ C+C F+G CE V + P G C +
Sbjct: 605 VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACE---EDVDECAQEPPPCGPGRCDN 661
Query: 447 ADQGYVCECPEGFM----GLDCRE-----RVPDDCECRNGGRCLGANTTL-CQCPLGF-- 494
+ C CP GF G C++ R P C GRC + C CP+GF
Sbjct: 662 TAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC---TYGRCENTEGSFQCVCPMGFQP 718
Query: 495 --FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC-VCHTDHNASHSLPSPCD----- 546
G CE C + CP G C+ GS+ C C + H+ + D
Sbjct: 719 NTAGSECE---DVDECENHLACP-GQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSG 774
Query: 547 SDPCFNGGSCDAHDDSYTCECPRGFH---GKHCEKARPHLCSSGP-CRNGGTCKEAGGEY 602
+ PC G C + S+ C C G+ G+ A + C G C G C G +
Sbjct: 775 APPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSF 834
Query: 603 HCSCP--YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSG----RHCEI 656
C+C YR R D C+ G C + G ++C CPPG C
Sbjct: 835 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 894
Query: 657 APSPCFRSPCVNGG-TCEDRDTDFFC--HCQAGYMGRRCQAEVDCGPPEEVKH------A 707
R P + G CE+ + C C GY E C +E +
Sbjct: 895 VDECRERGPALCGSQRCENSPGSYRCVRDCDPGY---HAGPEGTCDDVDECQEYGPEICG 951
Query: 708 TLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP-CLHGG 766
R T ACD GY + P G C ++DECR++ C
Sbjct: 952 AQRCENTPGSYRCTPACDPGYQPT---------PGG------GCQDVDECRNRSFCGAHA 996
Query: 767 SCQDRVAGYLCLCSTGYEGA----HCELERDECRAHPCRNGGS-CRNLPGAYVCRCP 818
CQ+ + CLC GYEGA HC ++ +EC G + C N+ G+++C CP
Sbjct: 997 VCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCP 1052
Score = 169 bits (428), Expect = 2e-41
Identities = 193/715 (26%), Positives = 263/715 (36%), Gaps = 154/715 (21%)
Query: 262 VGGCGHTTSVCLALRPC-----LNGGKC--IDDCVTGNP-------------SYTCSCLS 301
+G C +T L + P +G C +D+C T +P S+ C C +
Sbjct: 575 LGRCENTPGSFLCVCPAGYQAAPHGASCQDVDEC-TQSPGLCGRGACKNLPGSFRCVCPA 633
Query: 302 GFTGRRCHLDVNECASQPCQNG-GTCTHGINSFRCQCPAGFG--GPTCETAQSPC-DTKE 357
GF G C DV+ECA +P G G C + SF C CPAGF GP +PC D E
Sbjct: 634 GFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG-----APCQDVDE 688
Query: 358 CQHG------GQCQVENGSAVCVCQAGY----TGAACEMDVDDCSPDPCLNGGSCVDLVG 407
C G+C+ GS CVC G+ G+ CE DVD+C G CV+ G
Sbjct: 689 CARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPG 747
Query: 408 NYTCLCAEPFKGLRCETGDHPVPDACLSA--PCHNGGTCVDADQGYVCECPEGFMGLDCR 465
++ C G G D C S PC G C + + + C C G+ R
Sbjct: 748 SFQCRTCP--SGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGR 805
Query: 466 ERVPDDC----ECRNG------GRCLGANTTL-CQCPLGFF----GLLCEFEITAMPCNM 510
P C EC G G CL + + C C G+ G C + C+
Sbjct: 806 ---PGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC---LDVDECSE 859
Query: 511 NTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGS-------CDAHDDSY 563
C G C GS+ C+C H A L S D D C G C+ SY
Sbjct: 860 EDLC-QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 918
Query: 564 TC--ECPRGFHG---------KHCEKARPHLCSSGPCRNGGTCKEAGGEYHCS--CP--Y 608
C +C G+H C++ P +C + C N G Y C+ C Y
Sbjct: 919 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCEN------TPGSYRCTPACDPGY 972
Query: 609 RFT-GRHCEIGKPDSCASGP-CHNGGTCFHYIGKYKCDCPPGFSG----RHC-EIAPSPC 661
+ T G C+ D C + C C + G ++C C G+ G RHC ++
Sbjct: 973 QPTPGGGCQ--DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECET 1030
Query: 662 FRSPCVNGGTCEDRDTDFFCHC-------------------QAG-YMGRRCQAEVDCGPP 701
+ C CE+ + F C C AG + G + QA P
Sbjct: 1031 LQGVC-GAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1089
Query: 702 EEVKHATL--RFNGTRLGAVALYACDRGYSLSAPSRI-RVCQPHGVWSEPPQCLEIDE-- 756
L R + R G V + + +AP + + W E C + E
Sbjct: 1090 ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQEC--CCTVGEGW 1147
Query: 757 ---CRSQPCLHGGSCQDRVAGYLCLC--STGYEGAHCEL----ERDEC---RAHPCRNGG 804
CR Q C A Y LC GY +L + DEC R C++G
Sbjct: 1148 GSGCRIQQCPG-----TETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV 1202
Query: 805 SCRNLPGAYVCRCPAGFV----GVHCETEVDACDSSPCQHGGRCESGGGAYLCVC 855
PG Y C C G+ + C + D P GGRC + G+Y C C
Sbjct: 1203 CVNTAPG-YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
Score = 164 bits (416), Expect = 4e-40
Identities = 177/652 (27%), Positives = 232/652 (35%), Gaps = 125/652 (19%)
Query: 376 QAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFK----GLRCETGDH--PV 429
++G + C+ + C P G C+ YTC C F+ G RC D V
Sbjct: 474 ESGPSSGMCQRNPQVCGP------GRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV 527
Query: 430 PDACLSAPCHNGGTCVDADQGYVCECPEGF---------MGLDCRERVPDDCECRNGGRC 480
P C AP G C ++ + C C GF + +D RVP C+ GRC
Sbjct: 528 PPPC--AP----GRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL---GRC 578
Query: 481 LGA-NTTLCQCPLGF----FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDH 535
+ LC CP G+ G C+ C + G C GS+ CVC
Sbjct: 579 ENTPGSFLCVCPAGYQAAPHGASCQ---DVDECTQSPGLCGRGACKNLPGSFRCVCPAGF 635
Query: 536 NASHSLPSPCDSD---------PCFNGGSCDAHDDSYTCECPRGFH----GKHCEKARPH 582
S C+ D PC G CD S+ C CP GF G C+
Sbjct: 636 RGS-----ACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDEC 689
Query: 583 LCSSGPCRNGGTCKEAGGEYHCSCPYRF----TGRHCEIGKPDSCASGPCHNGGTCFHYI 638
S PC G C+ G + C CP F G CE D C + G C +
Sbjct: 690 ARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECE--DVDECENHLACPGQECVNSP 746
Query: 639 GKYKC-DCPPGFS---GRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQA 694
G ++C CP G GR ++ PC G C + + F C C GY +
Sbjct: 747 GSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP 806
Query: 695 EVDCGPPEEVKHATLRF-NGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEP--PQC 751
C E F +G L +AC C P G P C
Sbjct: 807 G-PCADVNECLEGDFCFPHGECLNTDGSFAC-------------TCAP-GYRPGPRGASC 851
Query: 752 LEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEG----AHCELERDECRAHPCRNGGS-- 805
L++DEC + G C + + C+C G+ A C L+ DECR GS
Sbjct: 852 LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERGPALCGSQR 910
Query: 806 CRNLPGAYVC--RCPAGFVGVHCETEVDACDSSPCQHGG-------RCESGGGAYLCVCP 856
C N PG+Y C C G+ H E D CQ G RCE+ G+Y C P
Sbjct: 911 CENSPGSYRCVRDCDPGY---HAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCT-P 966
Query: 857 ESFFGYH------CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTG----------E 900
GY C+ V + S CG C GS C C GY G
Sbjct: 967 ACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVN 1026
Query: 901 DCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSY 952
+C A E VE S + + PN P + G V +S G++
Sbjct: 1027 ECETLQGVCGAALCENVEGSFLCVC---PNSPEEFDPMTGRCVPPRTSAGTF 1075
Score = 149 bits (376), Expect = 2e-35
Identities = 172/660 (26%), Positives = 230/660 (34%), Gaps = 130/660 (19%)
Query: 323 GGTCTHGINSFRCQ--CPAGFGGPTCETAQSPCDTKECQH--GGQCQVENGSAVCVCQAG 378
GG C + R Q C G G A D + C G +V C
Sbjct: 228 GGECASPLPGLRTQEVCCRGAG-----LAWGVHDCQLCSERLGNSERVSAPDGPCPTGFE 282
Query: 379 YTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPF---KGLRCETGDHPVPDACLS 435
+CE DVD+C+ G C + G YTC+C + F H + +A
Sbjct: 283 RVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA--K 339
Query: 436 APCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQ------ 489
PC V D G C P R C C G+ G LC
Sbjct: 340 GPCFR----VLRDGG--CSLP------ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEG 387
Query: 490 ----CPL--GFFGLLCEFEITAMPCNMN--------------TQCPDGGYCMEHGGSYLC 529
CP G+ + P T P G+ H
Sbjct: 388 FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRP 447
Query: 530 VCHTDHNASHSLPSP-------------------CDSDPCFNG-GSCDAHDDSYTCECPR 569
D LP P C +P G G C + YTC C
Sbjct: 448 EPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDS 507
Query: 570 GF----HGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSC--PYRFTGRHCEIGKPDSC 623
GF G C PC G C+ + G + C C +R R E D C
Sbjct: 508 GFRLSPQGTRCIDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDEC 566
Query: 624 --ASGPCHNGGTCFHYIGKYKCDCPPGFS----GRHCEIAPSPCFRSPCVNG-GTCEDRD 676
PC + G C + G + C CP G+ G C+ C +SP + G G C++
Sbjct: 567 HRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQDV-DECTQSPGLCGRGACKNLP 624
Query: 677 TDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRI 736
F C C AG+ G C+ +VD E R + T AC G+ P
Sbjct: 625 GSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT--AGSFHCACPAGFRSRGPG-- 680
Query: 737 RVCQPHGVWSEPPQCLEIDEC-RSQPCLHGGSCQDRVAGYLCLCSTGYE----GAHCELE 791
C ++DEC RS P G C++ + C+C G++ G+ CE +
Sbjct: 681 ------------APCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-D 727
Query: 792 RDECRAHPCRNGGSCRNLPGAYVCR-CPAGFVGVH---CETEVDACDSS--PCQHGGRCE 845
DEC H G C N PG++ CR CP+G +H C T+VD C S PC G C
Sbjct: 728 VDECENHLACPGQECVNSPGSFQCRTCPSGH-HLHRGRC-TDVDECSSGAPPCGPHGHCT 785
Query: 846 SGGGAYLCVCPESFFGYH--------CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 897
+ G++ C C GY C V++ C G CL ++GS +CTC GY
Sbjct: 786 NTEGSFRCSCAP---GYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY 842
Score = 130 bits (328), Expect = 7e-30
Identities = 184/690 (26%), Positives = 244/690 (35%), Gaps = 161/690 (23%)
Query: 320 CQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379
C NGG C + RC CP F G C+ S G + + +
Sbjct: 90 CHNGGVC---VKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDE 146
Query: 380 TGAACEMDVDDCSPDPCLNGGSCVDLV-GNYTCLCAEPF----KGLRCETGDHPVPDACL 434
G A + V P V+ V G + AE R E P
Sbjct: 147 HGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAA-APYTVLAQ 205
Query: 435 SAPCHNG-------GTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGA-NTT 486
SAP +G G C +G C P GL R + C CR G G +
Sbjct: 206 SAPREDGYSDASGFGYCFRELRGGECASP--LPGL----RTQEVC-CRGAGLAWGVHDCQ 258
Query: 487 LCQ---------------CPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHG------G 525
LC CP G FE C +C GG C +HG G
Sbjct: 259 LCSERLGNSERVSAPDGPCPTG-------FERVNGSCEDVDECATGGRC-QHGECANTRG 310
Query: 526 SYLCVCHTDHNASHSLPSPCDSD--------PCF---NGGSCD----AHDDSYTCECPR- 569
Y CVC D S S C S PCF G C + C C R
Sbjct: 311 GYTCVC-PDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRV 369
Query: 570 -GFHGKHCEKARP-------HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPD 621
G+ C+ P +C +GP G ++ + R+ R P
Sbjct: 370 GKAWGRGCQLCPPFGSEGFREICPAGP-----------GYHYSASDLRYNTRPLGQEPPR 418
Query: 622 SCASGPCHNGGTCFHYIG---------------------KYKCDCPPGFSGRHC-EIAPS 659
S P T G + P ++G E PS
Sbjct: 419 VSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPS 478
Query: 660 P--CFRSPCVNG-GTCEDRDTDFFCHCQAGY----MGRRCQAEVDCG--PPEEVKHATLR 710
C R+P V G G C R + + C C +G+ G RC +C PP
Sbjct: 479 SGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPP--------- 529
Query: 711 FNGTRLGAVALYACDRGYSLSAPSRIR-VCQPHGVWSEP--PQCLEIDEC-RSQPCLHGG 766
C G ++P R VC P G + P +CL++DEC R P G
Sbjct: 530 ------------PCAPGRCENSPGSFRCVCGP-GFRAGPRAAECLDVDECHRVPPPCDLG 576
Query: 767 SCQDRVAGYLCLCSTGYE----GAHCELERDECRAHPCRNG-GSCRNLPGAYVCRCPAGF 821
C++ +LC+C GY+ GA C+ + DEC P G G+C+NLPG++ C CPAGF
Sbjct: 577 RCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGF 635
Query: 822 VGVHCETEVDACDSSPCQHG-GRCESGGGAYLCVCPESFF----GYHCETVSDPCFSSPC 876
G CE +VD C P G GRC++ G++ C CP F G C+ V + S P
Sbjct: 636 RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPP 695
Query: 877 GGRGYCLASNGSHSCTCKVGY----TGEDC 902
G C + GS C C +G+ G +C
Sbjct: 696 CTYGRCENTEGSFQCVCPMGFQPNTAGSEC 725
Score = 108 bits (270), Expect = 4e-23
Identities = 162/626 (25%), Positives = 208/626 (33%), Gaps = 161/626 (25%)
Query: 419 GLRCETGDHPVPDACLSAPCHNGGTCVDADQ-GYVCECPEGFMGLDCRERVPDDCECRNG 477
GLRC G P C T VD+ G GF C C NG
Sbjct: 42 GLRCVHG--PTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLC------PLICHNG 93
Query: 478 GRCLGANTTLCQCPLGFFGLLCEFEITAM--PCNMNTQCPDGGYCM--------EHGGSY 527
G C+ + C CP F G C+ + P Y M EHG +
Sbjct: 94 GVCVKPDR--CLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVAS 151
Query: 528 LCVCHTDHNASHSL--------PSPCDSDPCFNGGSCDA------------------HDD 561
+ H +H S+ P + +A +D
Sbjct: 152 MVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPRED 211
Query: 562 SYTCE-----CPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCS----------- 605
Y+ C R G C P L + C G A G + C
Sbjct: 212 GYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGL--AWGVHDCQLCSERLGNSER 269
Query: 606 -------CPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGF---SGRHCE 655
CP F + D CA+G G C + G Y C CP GF S R
Sbjct: 270 VSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
Query: 656 I-------APSPCFRSPCVNGGTCE----DRDTDFFCHCQ--AGYMGRRCQ--------- 693
I A PCFR + G C T C C GR CQ
Sbjct: 330 ISQHVISEAKGPCFR--VLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEG 387
Query: 694 -AEV-DCGPPEEVKHATLRFNGTRLGAV----------ALYACDRGYSLSAPSRIRVCQP 741
E+ GP + LR+N LG L A R + P+ +P
Sbjct: 388 FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRP 447
Query: 742 H----------------GVWSEPPQCLEIDE-------CRSQPCLHG-GSCQDRVAGYLC 777
W+ P EI E C+ P + G G C R +GY C
Sbjct: 448 EPRPDPRPGPELPLPSIPAWTGP----EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTC 503
Query: 778 LCSTGY----EGAHCELERDECR--AHPCRNGGSCRNLPGAYVCRCPAGF----VGVHCE 827
C +G+ +G C ++ DECR PC G C N PG++ C C GF C
Sbjct: 504 ACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAEC- 560
Query: 828 TEVDACD--SSPCQHGGRCESGGGAYLCVCPESF----FGYHCETVSDPCFSSP-CGGRG 880
+VD C PC GRCE+ G++LCVCP + G C+ V D C SP GRG
Sbjct: 561 LDVDECHRVPPPCDL-GRCENTPGSFLCVCPAGYQAAPHGASCQDV-DECTQSPGLCGRG 618
Query: 881 YCLASNGSHSCTCKVGYTGEDCAKEL 906
C GS C C G+ G C +++
Sbjct: 619 ACKNLPGSFRCVCPAGFRGSACEEDV 644
Score = 90.5 bits (223), Expect = 1e-17
Identities = 123/479 (25%), Positives = 161/479 (33%), Gaps = 132/479 (27%)
Query: 272 CLALRPCLNGGKCID--DCVTGNPSYTCSCLSGFT----GRRCHLDVNECASQPCQNGGT 325
C + CL G C +C+ + S+ C+C G+ G C LDV+EC+ + G
Sbjct: 809 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGI 867
Query: 326 CTHGINSFRCQCPAGF-GGPTCETAQSPCDTKECQHGG-------QCQVENGSAVCV--C 375
CT+ SF C CP G GP + D EC+ G +C+ GS CV C
Sbjct: 868 CTNTDGSFECICPPGHRAGPDLASC---LDVDECRERGPALCGSQRCENSPGSYRCVRDC 924
Query: 376 QAGYTGA---ACEMDVDDCS---PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPV 429
GY C+ DVD+C P+ C C + G+Y C A C+ G P
Sbjct: 925 DPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCTPA-------CDPGYQPT 975
Query: 430 P-------DACLS-------APCHN------------------GGTCVDADQGYVCECPE 457
P D C + A C N G CVD ++ CE +
Sbjct: 976 PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNE---CETLQ 1032
Query: 458 GFMGLDCRERVPDD--CECRNG--------GRCLGANTTLCQCPLGFFGLLCEFEITAMP 507
G G E V C C N GRC+ T+ P + A P
Sbjct: 1033 GVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARP 1092
Query: 508 CNMNTQCPDGGYCMEHG--GSYLCVCHTDHNASHSLPSPCDSDPCFN------------- 552
P G GS C+ D A P CD+ N
Sbjct: 1093 --PPPPLPRRPSTPRQGPVGSGRRECYFDTAA----PDACDNILARNVTWQECCCTVGEG 1146
Query: 553 -GGSC------DAHDDSYTCECPRGFHGK----------------HCEKARPHLCSSGPC 589
G C Y CP HG+ C+ R +C SG C
Sbjct: 1147 WGSGCRIQQCPGTETAEYQSLCP---HGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVC 1203
Query: 590 RNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASG-PCHNGGTCFHYIGKYKCDCPP 647
N G +CS Y + + E D CA P GG C + +G Y C C P
Sbjct: 1204 VNTAP----GYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1258
Score = 45.1 bits (105), Expect = 5e-04
Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 19/112 (16%)
Query: 288 CVTGNPSYTCSCLSGF---TGRRCHLDVNECA-SQPCQNGGTCTHGINSFRCQCPAGFGG 343
CV P Y+C C +G+ T R +D +ECA +P GG C + + S+ C C
Sbjct: 1203 CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL-- 1260
Query: 344 PTCETAQSPCDTKECQ----HGGQCQVENGSAVCVC-------QAGYTGAAC 384
+ +Q C + E Q + G C E G A VC QA YT C
Sbjct: 1261 -VLDGSQRRCVSNESQSLDDNLGVCWQEVG-ADLVCSHPRLDRQATYTECCC 1310
Score = 42.0 bits (97), Expect = 0.004
Identities = 63/229 (27%), Positives = 81/229 (35%), Gaps = 65/229 (28%)
Query: 306 RRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFG-GPTCETAQSP-CDTKE----CQ 359
R C+ D A C N + C C G G G C Q P +T E C
Sbjct: 1114 RECYFDT--AAPDACDN--ILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCP 1169
Query: 360 HG----------------GQCQV------ENGSAV-------CVCQAGY---TGAACEMD 387
HG +CQ+ ++G V C C GY T +D
Sbjct: 1170 HGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECID 1229
Query: 388 VDDCSPD-PCLNGGSCVDLVGNYTCLCAEPF----KGLRCETGDHPVPDACLSAPCHNGG 442
D+C+ + P GG CV+ VG+Y C C P RC + + D N G
Sbjct: 1230 NDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLD-------DNLG 1282
Query: 443 TC---VDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLC 488
C V AD VC P LD R+ +C C G G + LC
Sbjct: 1283 VCWQEVGAD--LVCSHPR----LD-RQATYTECCCLY-GEAWGMDCALC 1323
Score = 40.8 bits (94), Expect = 0.009
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 789 ELERDECRAHPCRNGGSCRNLPGAYVCRCPAGF----VGVHCETEVDACD----SSPCQH 840
ELE +EC G C +P + CRC G+ + C +++ CD +SP
Sbjct: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1522
Query: 841 GGRCESGGGAYLCVCPESFFGYH 863
RC + G++ C+C F H
Sbjct: 1523 NARCLNTDGSFRCICRPGFAPTH 1545
Score = 40.0 bits (92), Expect = 0.016
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 12/77 (15%)
Query: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFT---GRRCHLDVNEC----ASQPCQNGG 324
C L C NG CV +TC C G+ R +D+NEC A+ P
Sbjct: 1470 CGILDGCTNGR-----CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 325 TCTHGINSFRCQCPAGF 341
C + SFRC C GF
Sbjct: 1525 RCLNTDGSFRCICRPGF 1541
Score = 37.7 bits (86), Expect = 0.079
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCEL---ERDEC---- 795
G +EP + LE +EC G C G+ C C GY + + +EC
Sbjct: 1456 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1515
Query: 796 RAHPCRNGGSCRNLPGAYVCRCPAGFVGVH 825
A P C N G++ C C GF H
Sbjct: 1516 AASPLCVNARCLNTDGSFRCICRPGFAPTH 1545
Score = 33.1 bits (74), Expect = 1.9
Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 18/98 (18%)
Query: 407 GNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRE 466
G+Y AEP++ L E + + D C + G CV +G+ C C +G+ R
Sbjct: 1452 GSYAGSLAEPYEELEAE--ECGILDGCTN------GRCVRVPEGFTCRCFDGYRLDMTRM 1503
Query: 467 RVPDDCECRN---------GGRCLGANTTL-CQCPLGF 494
D EC RCL + + C C GF
Sbjct: 1504 ACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
Score = 31.6 bits (70), Expect = 5.6
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 11/82 (13%)
Query: 385 EMDVDDCSP-DPCLNGGSCVDLVGNYTCLCAEPFKGLRCE------TGDHPVPDACLSAP 437
E++ ++C D C NG CV + +TC C F G R + + +A ++P
Sbjct: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1519
Query: 438 CHNGGTCVDADQGYVCECPEGF 459
C++ D + C C GF
Sbjct: 1520 LCVNARCLNTDGSFRCICRPGF 1541
Score = 31.2 bits (69), Expect = 7.4
Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 12/66 (18%)
Query: 1295 QLPEHGSKDIGNVPGNCSENPCQNG-GTCVPGADAHSCDCGPGFK----GRRC--ELACI 1347
++PE G G C NP G G C+ ++C C GF+ G RC C
Sbjct: 471 EIPESGPSS-----GMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECR 525
Query: 1348 KVSRPC 1353
+V PC
Sbjct: 526 RVPPPC 531
Score = 31.2 bits (69), Expect = 7.4
Identities = 20/80 (25%), Positives = 29/80 (36%), Gaps = 13/80 (16%)
Query: 310 LDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPC-DTKECQH-------- 360
L+ EC G C F C+C F G + + C D EC
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASPLC 1521
Query: 361 -GGQCQVENGSAVCVCQAGY 379
+C +GS C+C+ G+
Sbjct: 1522 VNARCLNTDGSFRCICRPGF 1541
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 201 bits (512), Expect = 3e-51
Identities = 178/597 (29%), Positives = 242/597 (40%), Gaps = 104/597 (17%)
Query: 288 CVTGNPSYTCSCLSGF----TGRRCHLDVNEC--ASQPCQNGGTCTHGINSFRCQCPAGF 341
C++ YTC+C SGF G RC +DV+EC PC G C + SFRC C GF
Sbjct: 524 CISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGF 581
Query: 342 -GGP---------TCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYT----GAACEMD 387
GP C PCD G+C+ GS +CVC AGY GA+C+ D
Sbjct: 582 RAGPRAAECLDVDECHRVPPPCDL------GRCENTPGSFLCVCPAGYQAAPHGASCQ-D 634
Query: 388 VDDCSPDPCLNG-GSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVD 446
VD+C+ P L G G+C +L G++ C+C F+G CE V + P G C +
Sbjct: 635 VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACE---EDVDECAQEPPPCGPGRCDN 691
Query: 447 ADQGYVCECPEGFM----GLDCRE-----RVPDDCECRNGGRCLGANTTL-CQCPLGF-- 494
+ C CP GF G C++ R P C GRC + C CP+GF
Sbjct: 692 TAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC---TYGRCENTEGSFQCVCPMGFQP 748
Query: 495 --FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC-VCHTDHNASHSLPSPCD----- 546
G CE C + CP G C+ GS+ C C + H+ + D
Sbjct: 749 NTAGSECE---DVDECENHLACP-GQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSG 804
Query: 547 SDPCFNGGSCDAHDDSYTCECPRGFH---GKHCEKARPHLCSSGP-CRNGGTCKEAGGEY 602
+ PC G C + S+ C C G+ G+ A + C G C G C G +
Sbjct: 805 APPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSF 864
Query: 603 HCSCP--YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSG----RHCEI 656
C+C YR R D C+ G C + G ++C CPPG C
Sbjct: 865 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 924
Query: 657 APSPCFRSPCVNGG-TCEDRDTDFFC--HCQAGYMGRRCQAEVDCGPPEEVKH------A 707
R P + G CE+ + C C GY E C +E +
Sbjct: 925 VDECRERGPALCGSQRCENSPGSYRCVRDCDPGY---HAGPEGTCDDVDECQEYGPEICG 981
Query: 708 TLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP-CLHGG 766
R T ACD GY + P G C ++DECR++ C
Sbjct: 982 AQRCENTPGSYRCTPACDPGYQPT---------PGG------GCQDVDECRNRSFCGAHA 1026
Query: 767 SCQDRVAGYLCLCSTGYEGA----HCELERDECRAHPCRNGGS-CRNLPGAYVCRCP 818
CQ+ + CLC GYEGA HC ++ +EC G + C N+ G+++C CP
Sbjct: 1027 VCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCP 1082
Score = 169 bits (428), Expect = 2e-41
Identities = 193/715 (26%), Positives = 263/715 (36%), Gaps = 154/715 (21%)
Query: 262 VGGCGHTTSVCLALRPC-----LNGGKC--IDDCVTGNP-------------SYTCSCLS 301
+G C +T L + P +G C +D+C T +P S+ C C +
Sbjct: 605 LGRCENTPGSFLCVCPAGYQAAPHGASCQDVDEC-TQSPGLCGRGACKNLPGSFRCVCPA 663
Query: 302 GFTGRRCHLDVNECASQPCQNG-GTCTHGINSFRCQCPAGFG--GPTCETAQSPC-DTKE 357
GF G C DV+ECA +P G G C + SF C CPAGF GP +PC D E
Sbjct: 664 GFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG-----APCQDVDE 718
Query: 358 CQHG------GQCQVENGSAVCVCQAGY----TGAACEMDVDDCSPDPCLNGGSCVDLVG 407
C G+C+ GS CVC G+ G+ CE DVD+C G CV+ G
Sbjct: 719 CARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPG 777
Query: 408 NYTCLCAEPFKGLRCETGDHPVPDACLSA--PCHNGGTCVDADQGYVCECPEGFMGLDCR 465
++ C G G D C S PC G C + + + C C G+ R
Sbjct: 778 SFQCRTCP--SGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGR 835
Query: 466 ERVPDDC----ECRNG------GRCLGANTTL-CQCPLGFF----GLLCEFEITAMPCNM 510
P C EC G G CL + + C C G+ G C + C+
Sbjct: 836 ---PGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC---LDVDECSE 889
Query: 511 NTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGS-------CDAHDDSY 563
C G C GS+ C+C H A L S D D C G C+ SY
Sbjct: 890 EDLC-QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 948
Query: 564 TC--ECPRGFHG---------KHCEKARPHLCSSGPCRNGGTCKEAGGEYHCS--CP--Y 608
C +C G+H C++ P +C + C N G Y C+ C Y
Sbjct: 949 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCEN------TPGSYRCTPACDPGY 1002
Query: 609 RFT-GRHCEIGKPDSCASGP-CHNGGTCFHYIGKYKCDCPPGFSG----RHC-EIAPSPC 661
+ T G C+ D C + C C + G ++C C G+ G RHC ++
Sbjct: 1003 QPTPGGGCQ--DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECET 1060
Query: 662 FRSPCVNGGTCEDRDTDFFCHC-------------------QAG-YMGRRCQAEVDCGPP 701
+ C CE+ + F C C AG + G + QA P
Sbjct: 1061 LQGVC-GAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1119
Query: 702 EEVKHATL--RFNGTRLGAVALYACDRGYSLSAPSRI-RVCQPHGVWSEPPQCLEIDE-- 756
L R + R G V + + +AP + + W E C + E
Sbjct: 1120 ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQEC--CCTVGEGW 1177
Query: 757 ---CRSQPCLHGGSCQDRVAGYLCLC--STGYEGAHCEL----ERDEC---RAHPCRNGG 804
CR Q C A Y LC GY +L + DEC R C++G
Sbjct: 1178 GSGCRIQQCPG-----TETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV 1232
Query: 805 SCRNLPGAYVCRCPAGFV----GVHCETEVDACDSSPCQHGGRCESGGGAYLCVC 855
PG Y C C G+ + C + D P GGRC + G+Y C C
Sbjct: 1233 CVNTAPG-YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1286
Score = 164 bits (416), Expect = 4e-40
Identities = 177/652 (27%), Positives = 232/652 (35%), Gaps = 125/652 (19%)
Query: 376 QAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFK----GLRCETGDH--PV 429
++G + C+ + C P G C+ YTC C F+ G RC D V
Sbjct: 504 ESGPSSGMCQRNPQVCGP------GRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV 557
Query: 430 PDACLSAPCHNGGTCVDADQGYVCECPEGF---------MGLDCRERVPDDCECRNGGRC 480
P C AP G C ++ + C C GF + +D RVP C+ GRC
Sbjct: 558 PPPC--AP----GRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL---GRC 608
Query: 481 LGA-NTTLCQCPLGF----FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDH 535
+ LC CP G+ G C+ C + G C GS+ CVC
Sbjct: 609 ENTPGSFLCVCPAGYQAAPHGASCQ---DVDECTQSPGLCGRGACKNLPGSFRCVCPAGF 665
Query: 536 NASHSLPSPCDSD---------PCFNGGSCDAHDDSYTCECPRGFH----GKHCEKARPH 582
S C+ D PC G CD S+ C CP GF G C+
Sbjct: 666 RGS-----ACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDEC 719
Query: 583 LCSSGPCRNGGTCKEAGGEYHCSCPYRF----TGRHCEIGKPDSCASGPCHNGGTCFHYI 638
S PC G C+ G + C CP F G CE D C + G C +
Sbjct: 720 ARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECE--DVDECENHLACPGQECVNSP 776
Query: 639 GKYKC-DCPPGFS---GRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQA 694
G ++C CP G GR ++ PC G C + + F C C GY +
Sbjct: 777 GSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP 836
Query: 695 EVDCGPPEEVKHATLRF-NGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEP--PQC 751
C E F +G L +AC C P G P C
Sbjct: 837 G-PCADVNECLEGDFCFPHGECLNTDGSFAC-------------TCAP-GYRPGPRGASC 881
Query: 752 LEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEG----AHCELERDECRAHPCRNGGS-- 805
L++DEC + G C + + C+C G+ A C L+ DECR GS
Sbjct: 882 LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERGPALCGSQR 940
Query: 806 CRNLPGAYVC--RCPAGFVGVHCETEVDACDSSPCQHGG-------RCESGGGAYLCVCP 856
C N PG+Y C C G+ H E D CQ G RCE+ G+Y C P
Sbjct: 941 CENSPGSYRCVRDCDPGY---HAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCT-P 996
Query: 857 ESFFGYH------CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTG----------E 900
GY C+ V + S CG C GS C C GY G
Sbjct: 997 ACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVN 1056
Query: 901 DCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSY 952
+C A E VE S + + PN P + G V +S G++
Sbjct: 1057 ECETLQGVCGAALCENVEGSFLCVC---PNSPEEFDPMTGRCVPPRTSAGTF 1105
Score = 149 bits (376), Expect = 2e-35
Identities = 172/660 (26%), Positives = 230/660 (34%), Gaps = 130/660 (19%)
Query: 323 GGTCTHGINSFRCQ--CPAGFGGPTCETAQSPCDTKECQH--GGQCQVENGSAVCVCQAG 378
GG C + R Q C G G A D + C G +V C
Sbjct: 258 GGECASPLPGLRTQEVCCRGAG-----LAWGVHDCQLCSERLGNSERVSAPDGPCPTGFE 312
Query: 379 YTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPF---KGLRCETGDHPVPDACLS 435
+CE DVD+C+ G C + G YTC+C + F H + +A
Sbjct: 313 RVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA--K 369
Query: 436 APCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQ------ 489
PC V D G C P R C C G+ G LC
Sbjct: 370 GPCFR----VLRDGG--CSLP------ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEG 417
Query: 490 ----CPL--GFFGLLCEFEITAMPCNMN--------------TQCPDGGYCMEHGGSYLC 529
CP G+ + P T P G+ H
Sbjct: 418 FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRP 477
Query: 530 VCHTDHNASHSLPSP-------------------CDSDPCFNG-GSCDAHDDSYTCECPR 569
D LP P C +P G G C + YTC C
Sbjct: 478 EPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDS 537
Query: 570 GF----HGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSC--PYRFTGRHCEIGKPDSC 623
GF G C PC G C+ + G + C C +R R E D C
Sbjct: 538 GFRLSPQGTRCIDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDEC 596
Query: 624 --ASGPCHNGGTCFHYIGKYKCDCPPGFS----GRHCEIAPSPCFRSPCVNG-GTCEDRD 676
PC + G C + G + C CP G+ G C+ C +SP + G G C++
Sbjct: 597 HRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQDV-DECTQSPGLCGRGACKNLP 654
Query: 677 TDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRI 736
F C C AG+ G C+ +VD E R + T AC G+ P
Sbjct: 655 GSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT--AGSFHCACPAGFRSRGPG-- 710
Query: 737 RVCQPHGVWSEPPQCLEIDEC-RSQPCLHGGSCQDRVAGYLCLCSTGYE----GAHCELE 791
C ++DEC RS P G C++ + C+C G++ G+ CE +
Sbjct: 711 ------------APCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-D 757
Query: 792 RDECRAHPCRNGGSCRNLPGAYVCR-CPAGFVGVH---CETEVDACDSS--PCQHGGRCE 845
DEC H G C N PG++ CR CP+G +H C T+VD C S PC G C
Sbjct: 758 VDECENHLACPGQECVNSPGSFQCRTCPSGH-HLHRGRC-TDVDECSSGAPPCGPHGHCT 815
Query: 846 SGGGAYLCVCPESFFGYH--------CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 897
+ G++ C C GY C V++ C G CL ++GS +CTC GY
Sbjct: 816 NTEGSFRCSCAP---GYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY 872
Score = 130 bits (328), Expect = 7e-30
Identities = 184/690 (26%), Positives = 244/690 (35%), Gaps = 161/690 (23%)
Query: 320 CQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379
C NGG C + RC CP F G C+ S G + + +
Sbjct: 120 CHNGGVC---VKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDE 176
Query: 380 TGAACEMDVDDCSPDPCLNGGSCVDLV-GNYTCLCAEPF----KGLRCETGDHPVPDACL 434
G A + V P V+ V G + AE R E P
Sbjct: 177 HGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAA-APYTVLAQ 235
Query: 435 SAPCHNG-------GTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGA-NTT 486
SAP +G G C +G C P GL R + C CR G G +
Sbjct: 236 SAPREDGYSDASGFGYCFRELRGGECASP--LPGL----RTQEVC-CRGAGLAWGVHDCQ 288
Query: 487 LCQ---------------CPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHG------G 525
LC CP G FE C +C GG C +HG G
Sbjct: 289 LCSERLGNSERVSAPDGPCPTG-------FERVNGSCEDVDECATGGRC-QHGECANTRG 340
Query: 526 SYLCVCHTDHNASHSLPSPCDSD--------PCF---NGGSCD----AHDDSYTCECPR- 569
Y CVC D S S C S PCF G C + C C R
Sbjct: 341 GYTCVC-PDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRV 399
Query: 570 -GFHGKHCEKARP-------HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPD 621
G+ C+ P +C +GP G ++ + R+ R P
Sbjct: 400 GKAWGRGCQLCPPFGSEGFREICPAGP-----------GYHYSASDLRYNTRPLGQEPPR 448
Query: 622 SCASGPCHNGGTCFHYIG---------------------KYKCDCPPGFSGRHC-EIAPS 659
S P T G + P ++G E PS
Sbjct: 449 VSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPS 508
Query: 660 P--CFRSPCVNG-GTCEDRDTDFFCHCQAGY----MGRRCQAEVDCG--PPEEVKHATLR 710
C R+P V G G C R + + C C +G+ G RC +C PP
Sbjct: 509 SGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPP--------- 559
Query: 711 FNGTRLGAVALYACDRGYSLSAPSRIR-VCQPHGVWSEP--PQCLEIDEC-RSQPCLHGG 766
C G ++P R VC P G + P +CL++DEC R P G
Sbjct: 560 ------------PCAPGRCENSPGSFRCVCGP-GFRAGPRAAECLDVDECHRVPPPCDLG 606
Query: 767 SCQDRVAGYLCLCSTGYE----GAHCELERDECRAHPCRNG-GSCRNLPGAYVCRCPAGF 821
C++ +LC+C GY+ GA C+ + DEC P G G+C+NLPG++ C CPAGF
Sbjct: 607 RCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGF 665
Query: 822 VGVHCETEVDACDSSPCQHG-GRCESGGGAYLCVCPESFF----GYHCETVSDPCFSSPC 876
G CE +VD C P G GRC++ G++ C CP F G C+ V + S P
Sbjct: 666 RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPP 725
Query: 877 GGRGYCLASNGSHSCTCKVGY----TGEDC 902
G C + GS C C +G+ G +C
Sbjct: 726 CTYGRCENTEGSFQCVCPMGFQPNTAGSEC 755
Score = 104 bits (260), Expect = 5e-22
Identities = 148/570 (25%), Positives = 193/570 (33%), Gaps = 152/570 (26%)
Query: 474 CRNGGRCLGANTTLCQCPLGFFGLLCEFEITAM--PCNMNTQCPDGGYCM--------EH 523
C NGG C+ + C CP F G C+ + P Y M EH
Sbjct: 120 CHNGGVCVKPDR--CLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEH 177
Query: 524 GGSYLCVCHTDHNASHSL--------PSPCDSDPCFNGGSCDA----------------- 558
G + + H +H S+ P + +A
Sbjct: 178 GVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSA 237
Query: 559 -HDDSYTCE-----CPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCS------- 605
+D Y+ C R G C P L + C G A G + C
Sbjct: 238 PREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGL--AWGVHDCQLCSERLG 295
Query: 606 -----------CPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGF---SG 651
CP F + D CA+G G C + G Y C CP GF S
Sbjct: 296 NSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSS 355
Query: 652 RHCEI-------APSPCFRSPCVNGGTCE----DRDTDFFCHCQ--AGYMGRRCQ----- 693
R I A PCFR + G C T C C GR CQ
Sbjct: 356 RSSCISQHVISEAKGPCFR--VLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPF 413
Query: 694 -----AEV-DCGPPEEVKHATLRFNGTRLGAV----------ALYACDRGYSLSAPSRIR 737
E+ GP + LR+N LG L A R + P+
Sbjct: 414 GSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRL 473
Query: 738 VCQPH----------------GVWSEPPQCLEIDE-------CRSQPCLHG-GSCQDRVA 773
+P W+ P EI E C+ P + G G C R +
Sbjct: 474 EPRPEPRPDPRPGPELPLPSIPAWTGP----EIPESGPSSGMCQRNPQVCGPGRCISRPS 529
Query: 774 GYLCLCSTGY----EGAHCELERDECR--AHPCRNGGSCRNLPGAYVCRCPAGF----VG 823
GY C C +G+ +G C ++ DECR PC G C N PG++ C C GF
Sbjct: 530 GYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRA 587
Query: 824 VHCETEVDACD--SSPCQHGGRCESGGGAYLCVCPESF----FGYHCETVSDPCFSSP-C 876
C +VD C PC GRCE+ G++LCVCP + G C+ V D C SP
Sbjct: 588 AEC-LDVDECHRVPPPCDL-GRCENTPGSFLCVCPAGYQAAPHGASCQDV-DECTQSPGL 644
Query: 877 GGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
GRG C GS C C G+ G C +++
Sbjct: 645 CGRGACKNLPGSFRCVCPAGFRGSACEEDV 674
Score = 90.5 bits (223), Expect = 1e-17
Identities = 123/479 (25%), Positives = 161/479 (33%), Gaps = 132/479 (27%)
Query: 272 CLALRPCLNGGKCID--DCVTGNPSYTCSCLSGFT----GRRCHLDVNECASQPCQNGGT 325
C + CL G C +C+ + S+ C+C G+ G C LDV+EC+ + G
Sbjct: 839 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGI 897
Query: 326 CTHGINSFRCQCPAGF-GGPTCETAQSPCDTKECQHGG-------QCQVENGSAVCV--C 375
CT+ SF C CP G GP + D EC+ G +C+ GS CV C
Sbjct: 898 CTNTDGSFECICPPGHRAGPDLASC---LDVDECRERGPALCGSQRCENSPGSYRCVRDC 954
Query: 376 QAGYTGA---ACEMDVDDCS---PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPV 429
GY C+ DVD+C P+ C C + G+Y C A C+ G P
Sbjct: 955 DPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCTPA-------CDPGYQPT 1005
Query: 430 P-------DACLS-------APCHN------------------GGTCVDADQGYVCECPE 457
P D C + A C N G CVD ++ CE +
Sbjct: 1006 PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNE---CETLQ 1062
Query: 458 GFMGLDCRERVPDD--CECRNG--------GRCLGANTTLCQCPLGFFGLLCEFEITAMP 507
G G E V C C N GRC+ T+ P + A P
Sbjct: 1063 GVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARP 1122
Query: 508 CNMNTQCPDGGYCMEHG--GSYLCVCHTDHNASHSLPSPCDSDPCFN------------- 552
P G GS C+ D A P CD+ N
Sbjct: 1123 --PPPPLPRRPSTPRQGPVGSGRRECYFDTAA----PDACDNILARNVTWQECCCTVGEG 1176
Query: 553 -GGSC------DAHDDSYTCECPRGFHGK----------------HCEKARPHLCSSGPC 589
G C Y CP HG+ C+ R +C SG C
Sbjct: 1177 WGSGCRIQQCPGTETAEYQSLCP---HGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVC 1233
Query: 590 RNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASG-PCHNGGTCFHYIGKYKCDCPP 647
N G +CS Y + + E D CA P GG C + +G Y C C P
Sbjct: 1234 VNTAP----GYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Score = 45.1 bits (105), Expect = 5e-04
Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 19/112 (16%)
Query: 288 CVTGNPSYTCSCLSGF---TGRRCHLDVNECA-SQPCQNGGTCTHGINSFRCQCPAGFGG 343
CV P Y+C C +G+ T R +D +ECA +P GG C + + S+ C C
Sbjct: 1233 CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL-- 1290
Query: 344 PTCETAQSPCDTKECQ----HGGQCQVENGSAVCVC-------QAGYTGAAC 384
+ +Q C + E Q + G C E G A VC QA YT C
Sbjct: 1291 -VLDGSQRRCVSNESQSLDDNLGVCWQEVG-ADLVCSHPRLDRQATYTECCC 1340
Score = 42.0 bits (97), Expect = 0.004
Identities = 63/229 (27%), Positives = 81/229 (35%), Gaps = 65/229 (28%)
Query: 306 RRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFG-GPTCETAQSP-CDTKE----CQ 359
R C+ D A C N + C C G G G C Q P +T E C
Sbjct: 1144 RECYFDT--AAPDACDN--ILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCP 1199
Query: 360 HG----------------GQCQV------ENGSAV-------CVCQAGY---TGAACEMD 387
HG +CQ+ ++G V C C GY T +D
Sbjct: 1200 HGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECID 1259
Query: 388 VDDCSPD-PCLNGGSCVDLVGNYTCLCAEPF----KGLRCETGDHPVPDACLSAPCHNGG 442
D+C+ + P GG CV+ VG+Y C C P RC + + D N G
Sbjct: 1260 NDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLD-------DNLG 1312
Query: 443 TC---VDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLC 488
C V AD VC P LD R+ +C C G G + LC
Sbjct: 1313 VCWQEVGAD--LVCSHPR----LD-RQATYTECCCLY-GEAWGMDCALC 1353
Score = 40.8 bits (94), Expect = 0.009
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 789 ELERDECRAHPCRNGGSCRNLPGAYVCRCPAGF----VGVHCETEVDACD----SSPCQH 840
ELE +EC G C +P + CRC G+ + C +++ CD +SP
Sbjct: 1494 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1552
Query: 841 GGRCESGGGAYLCVCPESFFGYH 863
RC + G++ C+C F H
Sbjct: 1553 NARCLNTDGSFRCICRPGFAPTH 1575
Score = 40.0 bits (92), Expect = 0.016
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 12/77 (15%)
Query: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFT---GRRCHLDVNEC----ASQPCQNGG 324
C L C NG CV +TC C G+ R +D+NEC A+ P
Sbjct: 1500 CGILDGCTNGR-----CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 325 TCTHGINSFRCQCPAGF 341
C + SFRC C GF
Sbjct: 1555 RCLNTDGSFRCICRPGF 1571
Score = 37.7 bits (86), Expect = 0.079
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCEL---ERDEC---- 795
G +EP + LE +EC G C G+ C C GY + + +EC
Sbjct: 1486 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1545
Query: 796 RAHPCRNGGSCRNLPGAYVCRCPAGFVGVH 825
A P C N G++ C C GF H
Sbjct: 1546 AASPLCVNARCLNTDGSFRCICRPGFAPTH 1575
Score = 33.1 bits (74), Expect = 1.9
Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 18/98 (18%)
Query: 407 GNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRE 466
G+Y AEP++ L E + + D C + G CV +G+ C C +G+ R
Sbjct: 1482 GSYAGSLAEPYEELEAE--ECGILDGCTN------GRCVRVPEGFTCRCFDGYRLDMTRM 1533
Query: 467 RVPDDCECRN---------GGRCLGANTTL-CQCPLGF 494
D EC RCL + + C C GF
Sbjct: 1534 ACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1571
Score = 31.6 bits (70), Expect = 5.6
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 11/82 (13%)
Query: 385 EMDVDDCSP-DPCLNGGSCVDLVGNYTCLCAEPFKGLRCE------TGDHPVPDACLSAP 437
E++ ++C D C NG CV + +TC C F G R + + +A ++P
Sbjct: 1494 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1549
Query: 438 CHNGGTCVDADQGYVCECPEGF 459
C++ D + C C GF
Sbjct: 1550 LCVNARCLNTDGSFRCICRPGF 1571
Score = 31.2 bits (69), Expect = 7.4
Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 12/66 (18%)
Query: 1295 QLPEHGSKDIGNVPGNCSENPCQNG-GTCVPGADAHSCDCGPGFK----GRRC--ELACI 1347
++PE G G C NP G G C+ ++C C GF+ G RC C
Sbjct: 501 EIPESGPSS-----GMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECR 555
Query: 1348 KVSRPC 1353
+V PC
Sbjct: 556 RVPPPC 561
Score = 31.2 bits (69), Expect = 7.4
Identities = 20/80 (25%), Positives = 29/80 (36%), Gaps = 13/80 (16%)
Query: 310 LDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPC-DTKECQH-------- 360
L+ EC G C F C+C F G + + C D EC
Sbjct: 1495 LEAEECGILDGCTNGRCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASPLC 1551
Query: 361 -GGQCQVENGSAVCVCQAGY 379
+C +GS C+C+ G+
Sbjct: 1552 VNARCLNTDGSFRCICRPGF 1571
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 201 bits (512), Expect = 3e-51
Identities = 178/597 (29%), Positives = 242/597 (40%), Gaps = 104/597 (17%)
Query: 288 CVTGNPSYTCSCLSGF----TGRRCHLDVNEC--ASQPCQNGGTCTHGINSFRCQCPAGF 341
C++ YTC+C SGF G RC +DV+EC PC G C + SFRC C GF
Sbjct: 561 CISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGF 618
Query: 342 -GGP---------TCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYT----GAACEMD 387
GP C PCD G+C+ GS +CVC AGY GA+C+ D
Sbjct: 619 RAGPRAAECLDVDECHRVPPPCDL------GRCENTPGSFLCVCPAGYQAAPHGASCQ-D 671
Query: 388 VDDCSPDPCLNG-GSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVD 446
VD+C+ P L G G+C +L G++ C+C F+G CE V + P G C +
Sbjct: 672 VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACE---EDVDECAQEPPPCGPGRCDN 728
Query: 447 ADQGYVCECPEGFM----GLDCRE-----RVPDDCECRNGGRCLGANTTL-CQCPLGF-- 494
+ C CP GF G C++ R P C GRC + C CP+GF
Sbjct: 729 TAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC---TYGRCENTEGSFQCVCPMGFQP 785
Query: 495 --FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC-VCHTDHNASHSLPSPCD----- 546
G CE C + CP G C+ GS+ C C + H+ + D
Sbjct: 786 NTAGSECE---DVDECENHLACP-GQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSG 841
Query: 547 SDPCFNGGSCDAHDDSYTCECPRGFH---GKHCEKARPHLCSSGP-CRNGGTCKEAGGEY 602
+ PC G C + S+ C C G+ G+ A + C G C G C G +
Sbjct: 842 APPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSF 901
Query: 603 HCSCP--YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSG----RHCEI 656
C+C YR R D C+ G C + G ++C CPPG C
Sbjct: 902 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 961
Query: 657 APSPCFRSPCVNGG-TCEDRDTDFFC--HCQAGYMGRRCQAEVDCGPPEEVKH------A 707
R P + G CE+ + C C GY E C +E +
Sbjct: 962 VDECRERGPALCGSQRCENSPGSYRCVRDCDPGY---HAGPEGTCDDVDECQEYGPEICG 1018
Query: 708 TLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP-CLHGG 766
R T ACD GY + P G C ++DECR++ C
Sbjct: 1019 AQRCENTPGSYRCTPACDPGYQPT---------PGG------GCQDVDECRNRSFCGAHA 1063
Query: 767 SCQDRVAGYLCLCSTGYEGA----HCELERDECRAHPCRNGGS-CRNLPGAYVCRCP 818
CQ+ + CLC GYEGA HC ++ +EC G + C N+ G+++C CP
Sbjct: 1064 VCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCP 1119
Score = 169 bits (428), Expect = 2e-41
Identities = 193/715 (26%), Positives = 263/715 (36%), Gaps = 154/715 (21%)
Query: 262 VGGCGHTTSVCLALRPC-----LNGGKC--IDDCVTGNP-------------SYTCSCLS 301
+G C +T L + P +G C +D+C T +P S+ C C +
Sbjct: 642 LGRCENTPGSFLCVCPAGYQAAPHGASCQDVDEC-TQSPGLCGRGACKNLPGSFRCVCPA 700
Query: 302 GFTGRRCHLDVNECASQPCQNG-GTCTHGINSFRCQCPAGFG--GPTCETAQSPC-DTKE 357
GF G C DV+ECA +P G G C + SF C CPAGF GP +PC D E
Sbjct: 701 GFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG-----APCQDVDE 755
Query: 358 CQHG------GQCQVENGSAVCVCQAGY----TGAACEMDVDDCSPDPCLNGGSCVDLVG 407
C G+C+ GS CVC G+ G+ CE DVD+C G CV+ G
Sbjct: 756 CARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPG 814
Query: 408 NYTCLCAEPFKGLRCETGDHPVPDACLSA--PCHNGGTCVDADQGYVCECPEGFMGLDCR 465
++ C G G D C S PC G C + + + C C G+ R
Sbjct: 815 SFQCRTCP--SGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGR 872
Query: 466 ERVPDDC----ECRNG------GRCLGANTTL-CQCPLGFF----GLLCEFEITAMPCNM 510
P C EC G G CL + + C C G+ G C + C+
Sbjct: 873 ---PGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC---LDVDECSE 926
Query: 511 NTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGS-------CDAHDDSY 563
C G C GS+ C+C H A L S D D C G C+ SY
Sbjct: 927 EDLC-QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 985
Query: 564 TC--ECPRGFHG---------KHCEKARPHLCSSGPCRNGGTCKEAGGEYHCS--CP--Y 608
C +C G+H C++ P +C + C N G Y C+ C Y
Sbjct: 986 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCEN------TPGSYRCTPACDPGY 1039
Query: 609 RFT-GRHCEIGKPDSCASGP-CHNGGTCFHYIGKYKCDCPPGFSG----RHC-EIAPSPC 661
+ T G C+ D C + C C + G ++C C G+ G RHC ++
Sbjct: 1040 QPTPGGGCQ--DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECET 1097
Query: 662 FRSPCVNGGTCEDRDTDFFCHC-------------------QAG-YMGRRCQAEVDCGPP 701
+ C CE+ + F C C AG + G + QA P
Sbjct: 1098 LQGVC-GAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1156
Query: 702 EEVKHATL--RFNGTRLGAVALYACDRGYSLSAPSRI-RVCQPHGVWSEPPQCLEIDE-- 756
L R + R G V + + +AP + + W E C + E
Sbjct: 1157 ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQEC--CCTVGEGW 1214
Query: 757 ---CRSQPCLHGGSCQDRVAGYLCLC--STGYEGAHCEL----ERDEC---RAHPCRNGG 804
CR Q C A Y LC GY +L + DEC R C++G
Sbjct: 1215 GSGCRIQQCPG-----TETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV 1269
Query: 805 SCRNLPGAYVCRCPAGFV----GVHCETEVDACDSSPCQHGGRCESGGGAYLCVC 855
PG Y C C G+ + C + D P GGRC + G+Y C C
Sbjct: 1270 CVNTAPG-YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1323
Score = 164 bits (416), Expect = 4e-40
Identities = 177/652 (27%), Positives = 232/652 (35%), Gaps = 125/652 (19%)
Query: 376 QAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFK----GLRCETGDH--PV 429
++G + C+ + C P G C+ YTC C F+ G RC D V
Sbjct: 541 ESGPSSGMCQRNPQVCGP------GRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV 594
Query: 430 PDACLSAPCHNGGTCVDADQGYVCECPEGF---------MGLDCRERVPDDCECRNGGRC 480
P C AP G C ++ + C C GF + +D RVP C+ GRC
Sbjct: 595 PPPC--AP----GRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL---GRC 645
Query: 481 LGA-NTTLCQCPLGF----FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDH 535
+ LC CP G+ G C+ C + G C GS+ CVC
Sbjct: 646 ENTPGSFLCVCPAGYQAAPHGASCQ---DVDECTQSPGLCGRGACKNLPGSFRCVCPAGF 702
Query: 536 NASHSLPSPCDSD---------PCFNGGSCDAHDDSYTCECPRGFH----GKHCEKARPH 582
S C+ D PC G CD S+ C CP GF G C+
Sbjct: 703 RGS-----ACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDEC 756
Query: 583 LCSSGPCRNGGTCKEAGGEYHCSCPYRF----TGRHCEIGKPDSCASGPCHNGGTCFHYI 638
S PC G C+ G + C CP F G CE D C + G C +
Sbjct: 757 ARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECE--DVDECENHLACPGQECVNSP 813
Query: 639 GKYKC-DCPPGFS---GRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQA 694
G ++C CP G GR ++ PC G C + + F C C GY +
Sbjct: 814 GSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP 873
Query: 695 EVDCGPPEEVKHATLRF-NGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEP--PQC 751
C E F +G L +AC C P G P C
Sbjct: 874 G-PCADVNECLEGDFCFPHGECLNTDGSFAC-------------TCAP-GYRPGPRGASC 918
Query: 752 LEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEG----AHCELERDECRAHPCRNGGS-- 805
L++DEC + G C + + C+C G+ A C L+ DECR GS
Sbjct: 919 LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERGPALCGSQR 977
Query: 806 CRNLPGAYVC--RCPAGFVGVHCETEVDACDSSPCQHGG-------RCESGGGAYLCVCP 856
C N PG+Y C C G+ H E D CQ G RCE+ G+Y C P
Sbjct: 978 CENSPGSYRCVRDCDPGY---HAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCT-P 1033
Query: 857 ESFFGYH------CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTG----------E 900
GY C+ V + S CG C GS C C GY G
Sbjct: 1034 ACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVN 1093
Query: 901 DCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSY 952
+C A E VE S + + PN P + G V +S G++
Sbjct: 1094 ECETLQGVCGAALCENVEGSFLCVC---PNSPEEFDPMTGRCVPPRTSAGTF 1142
Score = 149 bits (376), Expect = 2e-35
Identities = 172/660 (26%), Positives = 230/660 (34%), Gaps = 130/660 (19%)
Query: 323 GGTCTHGINSFRCQ--CPAGFGGPTCETAQSPCDTKECQH--GGQCQVENGSAVCVCQAG 378
GG C + R Q C G G A D + C G +V C
Sbjct: 295 GGECASPLPGLRTQEVCCRGAG-----LAWGVHDCQLCSERLGNSERVSAPDGPCPTGFE 349
Query: 379 YTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPF---KGLRCETGDHPVPDACLS 435
+CE DVD+C+ G C + G YTC+C + F H + +A
Sbjct: 350 RVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA--K 406
Query: 436 APCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQ------ 489
PC V D G C P R C C G+ G LC
Sbjct: 407 GPCFR----VLRDGG--CSLP------ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEG 454
Query: 490 ----CPL--GFFGLLCEFEITAMPCNMN--------------TQCPDGGYCMEHGGSYLC 529
CP G+ + P T P G+ H
Sbjct: 455 FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRP 514
Query: 530 VCHTDHNASHSLPSP-------------------CDSDPCFNG-GSCDAHDDSYTCECPR 569
D LP P C +P G G C + YTC C
Sbjct: 515 EPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDS 574
Query: 570 GF----HGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSC--PYRFTGRHCEIGKPDSC 623
GF G C PC G C+ + G + C C +R R E D C
Sbjct: 575 GFRLSPQGTRCIDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDEC 633
Query: 624 --ASGPCHNGGTCFHYIGKYKCDCPPGFS----GRHCEIAPSPCFRSPCVNG-GTCEDRD 676
PC + G C + G + C CP G+ G C+ C +SP + G G C++
Sbjct: 634 HRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQDV-DECTQSPGLCGRGACKNLP 691
Query: 677 TDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRI 736
F C C AG+ G C+ +VD E R + T AC G+ P
Sbjct: 692 GSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT--AGSFHCACPAGFRSRGPG-- 747
Query: 737 RVCQPHGVWSEPPQCLEIDEC-RSQPCLHGGSCQDRVAGYLCLCSTGYE----GAHCELE 791
C ++DEC RS P G C++ + C+C G++ G+ CE +
Sbjct: 748 ------------APCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-D 794
Query: 792 RDECRAHPCRNGGSCRNLPGAYVCR-CPAGFVGVH---CETEVDACDSS--PCQHGGRCE 845
DEC H G C N PG++ CR CP+G +H C T+VD C S PC G C
Sbjct: 795 VDECENHLACPGQECVNSPGSFQCRTCPSGH-HLHRGRC-TDVDECSSGAPPCGPHGHCT 852
Query: 846 SGGGAYLCVCPESFFGYH--------CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 897
+ G++ C C GY C V++ C G CL ++GS +CTC GY
Sbjct: 853 NTEGSFRCSCAP---GYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY 909
Score = 130 bits (328), Expect = 7e-30
Identities = 184/690 (26%), Positives = 244/690 (35%), Gaps = 161/690 (23%)
Query: 320 CQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379
C NGG C + RC CP F G C+ S G + + +
Sbjct: 157 CHNGGVC---VKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDE 213
Query: 380 TGAACEMDVDDCSPDPCLNGGSCVDLV-GNYTCLCAEPF----KGLRCETGDHPVPDACL 434
G A + V P V+ V G + AE R E P
Sbjct: 214 HGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAA-APYTVLAQ 272
Query: 435 SAPCHNG-------GTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGA-NTT 486
SAP +G G C +G C P GL R + C CR G G +
Sbjct: 273 SAPREDGYSDASGFGYCFRELRGGECASP--LPGL----RTQEVC-CRGAGLAWGVHDCQ 325
Query: 487 LCQ---------------CPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHG------G 525
LC CP G FE C +C GG C +HG G
Sbjct: 326 LCSERLGNSERVSAPDGPCPTG-------FERVNGSCEDVDECATGGRC-QHGECANTRG 377
Query: 526 SYLCVCHTDHNASHSLPSPCDSD--------PCF---NGGSCD----AHDDSYTCECPR- 569
Y CVC D S S C S PCF G C + C C R
Sbjct: 378 GYTCVC-PDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRV 436
Query: 570 -GFHGKHCEKARP-------HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPD 621
G+ C+ P +C +GP G ++ + R+ R P
Sbjct: 437 GKAWGRGCQLCPPFGSEGFREICPAGP-----------GYHYSASDLRYNTRPLGQEPPR 485
Query: 622 SCASGPCHNGGTCFHYIG---------------------KYKCDCPPGFSGRHC-EIAPS 659
S P T G + P ++G E PS
Sbjct: 486 VSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPS 545
Query: 660 P--CFRSPCVNG-GTCEDRDTDFFCHCQAGY----MGRRCQAEVDCG--PPEEVKHATLR 710
C R+P V G G C R + + C C +G+ G RC +C PP
Sbjct: 546 SGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPP--------- 596
Query: 711 FNGTRLGAVALYACDRGYSLSAPSRIR-VCQPHGVWSEP--PQCLEIDEC-RSQPCLHGG 766
C G ++P R VC P G + P +CL++DEC R P G
Sbjct: 597 ------------PCAPGRCENSPGSFRCVCGP-GFRAGPRAAECLDVDECHRVPPPCDLG 643
Query: 767 SCQDRVAGYLCLCSTGYE----GAHCELERDECRAHPCRNG-GSCRNLPGAYVCRCPAGF 821
C++ +LC+C GY+ GA C+ + DEC P G G+C+NLPG++ C CPAGF
Sbjct: 644 RCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGF 702
Query: 822 VGVHCETEVDACDSSPCQHG-GRCESGGGAYLCVCPESFF----GYHCETVSDPCFSSPC 876
G CE +VD C P G GRC++ G++ C CP F G C+ V + S P
Sbjct: 703 RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPP 762
Query: 877 GGRGYCLASNGSHSCTCKVGY----TGEDC 902
G C + GS C C +G+ G +C
Sbjct: 763 CTYGRCENTEGSFQCVCPMGFQPNTAGSEC 792
Score = 104 bits (260), Expect = 5e-22
Identities = 148/570 (25%), Positives = 193/570 (33%), Gaps = 152/570 (26%)
Query: 474 CRNGGRCLGANTTLCQCPLGFFGLLCEFEITAM--PCNMNTQCPDGGYCM--------EH 523
C NGG C+ + C CP F G C+ + P Y M EH
Sbjct: 157 CHNGGVCVKPDR--CLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEH 214
Query: 524 GGSYLCVCHTDHNASHSL--------PSPCDSDPCFNGGSCDA----------------- 558
G + + H +H S+ P + +A
Sbjct: 215 GVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSA 274
Query: 559 -HDDSYTCE-----CPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCS------- 605
+D Y+ C R G C P L + C G A G + C
Sbjct: 275 PREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGL--AWGVHDCQLCSERLG 332
Query: 606 -----------CPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGF---SG 651
CP F + D CA+G G C + G Y C CP GF S
Sbjct: 333 NSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSS 392
Query: 652 RHCEI-------APSPCFRSPCVNGGTCE----DRDTDFFCHCQ--AGYMGRRCQ----- 693
R I A PCFR + G C T C C GR CQ
Sbjct: 393 RSSCISQHVISEAKGPCFR--VLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPF 450
Query: 694 -----AEV-DCGPPEEVKHATLRFNGTRLGAV----------ALYACDRGYSLSAPSRIR 737
E+ GP + LR+N LG L A R + P+
Sbjct: 451 GSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRL 510
Query: 738 VCQPH----------------GVWSEPPQCLEIDE-------CRSQPCLHG-GSCQDRVA 773
+P W+ P EI E C+ P + G G C R +
Sbjct: 511 EPRPEPRPDPRPGPELPLPSIPAWTGP----EIPESGPSSGMCQRNPQVCGPGRCISRPS 566
Query: 774 GYLCLCSTGY----EGAHCELERDECR--AHPCRNGGSCRNLPGAYVCRCPAGF----VG 823
GY C C +G+ +G C ++ DECR PC G C N PG++ C C GF
Sbjct: 567 GYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRA 624
Query: 824 VHCETEVDACD--SSPCQHGGRCESGGGAYLCVCPESF----FGYHCETVSDPCFSSP-C 876
C +VD C PC GRCE+ G++LCVCP + G C+ V D C SP
Sbjct: 625 AEC-LDVDECHRVPPPCDL-GRCENTPGSFLCVCPAGYQAAPHGASCQDV-DECTQSPGL 681
Query: 877 GGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
GRG C GS C C G+ G C +++
Sbjct: 682 CGRGACKNLPGSFRCVCPAGFRGSACEEDV 711
Score = 90.5 bits (223), Expect = 1e-17
Identities = 123/479 (25%), Positives = 161/479 (33%), Gaps = 132/479 (27%)
Query: 272 CLALRPCLNGGKCID--DCVTGNPSYTCSCLSGFT----GRRCHLDVNECASQPCQNGGT 325
C + CL G C +C+ + S+ C+C G+ G C LDV+EC+ + G
Sbjct: 876 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGI 934
Query: 326 CTHGINSFRCQCPAGF-GGPTCETAQSPCDTKECQHGG-------QCQVENGSAVCV--C 375
CT+ SF C CP G GP + D EC+ G +C+ GS CV C
Sbjct: 935 CTNTDGSFECICPPGHRAGPDLASC---LDVDECRERGPALCGSQRCENSPGSYRCVRDC 991
Query: 376 QAGYTGA---ACEMDVDDCS---PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPV 429
GY C+ DVD+C P+ C C + G+Y C A C+ G P
Sbjct: 992 DPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCTPA-------CDPGYQPT 1042
Query: 430 P-------DACLS-------APCHN------------------GGTCVDADQGYVCECPE 457
P D C + A C N G CVD ++ CE +
Sbjct: 1043 PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNE---CETLQ 1099
Query: 458 GFMGLDCRERVPDD--CECRNG--------GRCLGANTTLCQCPLGFFGLLCEFEITAMP 507
G G E V C C N GRC+ T+ P + A P
Sbjct: 1100 GVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARP 1159
Query: 508 CNMNTQCPDGGYCMEHG--GSYLCVCHTDHNASHSLPSPCDSDPCFN------------- 552
P G GS C+ D A P CD+ N
Sbjct: 1160 --PPPPLPRRPSTPRQGPVGSGRRECYFDTAA----PDACDNILARNVTWQECCCTVGEG 1213
Query: 553 -GGSC------DAHDDSYTCECPRGFHGK----------------HCEKARPHLCSSGPC 589
G C Y CP HG+ C+ R +C SG C
Sbjct: 1214 WGSGCRIQQCPGTETAEYQSLCP---HGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVC 1270
Query: 590 RNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASG-PCHNGGTCFHYIGKYKCDCPP 647
N G +CS Y + + E D CA P GG C + +G Y C C P
Sbjct: 1271 VNTAP----GYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Score = 45.1 bits (105), Expect = 5e-04
Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 19/112 (16%)
Query: 288 CVTGNPSYTCSCLSGF---TGRRCHLDVNECA-SQPCQNGGTCTHGINSFRCQCPAGFGG 343
CV P Y+C C +G+ T R +D +ECA +P GG C + + S+ C C
Sbjct: 1270 CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL-- 1327
Query: 344 PTCETAQSPCDTKECQ----HGGQCQVENGSAVCVC-------QAGYTGAAC 384
+ +Q C + E Q + G C E G A VC QA YT C
Sbjct: 1328 -VLDGSQRRCVSNESQSLDDNLGVCWQEVG-ADLVCSHPRLDRQATYTECCC 1377
Score = 42.0 bits (97), Expect = 0.004
Identities = 63/229 (27%), Positives = 81/229 (35%), Gaps = 65/229 (28%)
Query: 306 RRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFG-GPTCETAQSP-CDTKE----CQ 359
R C+ D A C N + C C G G G C Q P +T E C
Sbjct: 1181 RECYFDT--AAPDACDN--ILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCP 1236
Query: 360 HG----------------GQCQV------ENGSAV-------CVCQAGY---TGAACEMD 387
HG +CQ+ ++G V C C GY T +D
Sbjct: 1237 HGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECID 1296
Query: 388 VDDCSPD-PCLNGGSCVDLVGNYTCLCAEPF----KGLRCETGDHPVPDACLSAPCHNGG 442
D+C+ + P GG CV+ VG+Y C C P RC + + D N G
Sbjct: 1297 NDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLD-------DNLG 1349
Query: 443 TC---VDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLC 488
C V AD VC P LD R+ +C C G G + LC
Sbjct: 1350 VCWQEVGAD--LVCSHPR----LD-RQATYTECCCLY-GEAWGMDCALC 1390
Score = 40.8 bits (94), Expect = 0.009
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 789 ELERDECRAHPCRNGGSCRNLPGAYVCRCPAGF----VGVHCETEVDACD----SSPCQH 840
ELE +EC G C +P + CRC G+ + C +++ CD +SP
Sbjct: 1531 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1589
Query: 841 GGRCESGGGAYLCVCPESFFGYH 863
RC + G++ C+C F H
Sbjct: 1590 NARCLNTDGSFRCICRPGFAPTH 1612
Score = 40.0 bits (92), Expect = 0.016
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 12/77 (15%)
Query: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFT---GRRCHLDVNEC----ASQPCQNGG 324
C L C NG CV +TC C G+ R +D+NEC A+ P
Sbjct: 1537 CGILDGCTNGR-----CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 325 TCTHGINSFRCQCPAGF 341
C + SFRC C GF
Sbjct: 1592 RCLNTDGSFRCICRPGF 1608
Score = 37.7 bits (86), Expect = 0.079
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCEL---ERDEC---- 795
G +EP + LE +EC G C G+ C C GY + + +EC
Sbjct: 1523 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1582
Query: 796 RAHPCRNGGSCRNLPGAYVCRCPAGFVGVH 825
A P C N G++ C C GF H
Sbjct: 1583 AASPLCVNARCLNTDGSFRCICRPGFAPTH 1612
Score = 33.1 bits (74), Expect = 1.9
Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 18/98 (18%)
Query: 407 GNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRE 466
G+Y AEP++ L E + + D C + G CV +G+ C C +G+ R
Sbjct: 1519 GSYAGSLAEPYEELEAE--ECGILDGCTN------GRCVRVPEGFTCRCFDGYRLDMTRM 1570
Query: 467 RVPDDCECRN---------GGRCLGANTTL-CQCPLGF 494
D EC RCL + + C C GF
Sbjct: 1571 ACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1608
Score = 31.6 bits (70), Expect = 5.6
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 11/82 (13%)
Query: 385 EMDVDDCSP-DPCLNGGSCVDLVGNYTCLCAEPFKGLRCE------TGDHPVPDACLSAP 437
E++ ++C D C NG CV + +TC C F G R + + +A ++P
Sbjct: 1531 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1586
Query: 438 CHNGGTCVDADQGYVCECPEGF 459
C++ D + C C GF
Sbjct: 1587 LCVNARCLNTDGSFRCICRPGF 1608
Score = 31.2 bits (69), Expect = 7.4
Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 12/66 (18%)
Query: 1295 QLPEHGSKDIGNVPGNCSENPCQNG-GTCVPGADAHSCDCGPGFK----GRRC--ELACI 1347
++PE G G C NP G G C+ ++C C GF+ G RC C
Sbjct: 538 EIPESGPSS-----GMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECR 592
Query: 1348 KVSRPC 1353
+V PC
Sbjct: 593 RVPPPC 598
Score = 31.2 bits (69), Expect = 7.4
Identities = 20/80 (25%), Positives = 29/80 (36%), Gaps = 13/80 (16%)
Query: 310 LDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPC-DTKECQH-------- 360
L+ EC G C F C+C F G + + C D EC
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASPLC 1588
Query: 361 -GGQCQVENGSAVCVCQAGY 379
+C +GS C+C+ G+
Sbjct: 1589 VNARCLNTDGSFRCICRPGF 1608
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 201 bits (510), Expect = 5e-51
Identities = 206/743 (27%), Positives = 273/743 (36%), Gaps = 184/743 (24%)
Query: 284 CIDDCVTGN--PSYTCSCLSGFTGRRCHLDVN------ECASQ-PCQNGGTCTHGINSFR 334
C D CV G TC C G+ G C + C S+ C+NG C +
Sbjct: 109 CADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGA-- 166
Query: 335 CQCPAGFGGPTCE------TAQSPCDTK-ECQHGGQCQVENGSAVCVCQAGYTGAACEMD 387
C C AGF G CE T + C + +CQ+G C G C C GYTGA CE
Sbjct: 167 CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE--CRCPPGYTGAFCE-- 222
Query: 388 VDDCSPD----------PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLS-- 435
D C P PC NGG C + G C C + G C P P+
Sbjct: 223 -DLCPPGKHGPQCEQRCPCQNGGVCHHVTGE--CSCPSGWMGTVC---GQPCPEGRFGKN 276
Query: 436 ----APCHNGGTCVDADQGYVCECPEGFMGLDCRERVP---------DDCECRNGGRCLG 482
CHNGGTC DA G C C G+ G C++ P + C+C NGG+C
Sbjct: 277 CSQECQCHNGGTC-DAATGQ-CHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYH 334
Query: 483 ANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNAS-HSL 541
+ C C GF G CE + CP+G Y ++ C CH ++ S H +
Sbjct: 335 VSGA-CLCEAGFAGERCEARL----------CPEGLYGIKCDKR--CPCHLENTHSCHPM 381
Query: 542 PSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE 601
C P ++G C+ C GF+G+ C++ +CS C+NG C G+
Sbjct: 382 SGECACKPGWSGLYCNE-------TCSPGFYGEACQQ----ICS---CQNGADCDSVTGK 427
Query: 602 YHCSCPYRFTGRHCEIGKP-----DSCASG-PCHNGGTCFHYIGKYKCDCPPGFSGRHCE 655
C+C F G C P +C+S C N C G C C G+ G C
Sbjct: 428 --CTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGS--CTCKAGWHGVDCS 483
Query: 656 I-APSPCF------RSPCVNGGTCEDRDTDFFCH-----------CQAGYMGRRCQAEVD 697
I PS + C+NGG C D C CQ G G C D
Sbjct: 484 IRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCD 543
Query: 698 CGPPEEVKHATLR------FNGTRLGAVALYA-----------CDRGYSLSAPSRI---- 736
C + T ++G +V C G S S I
Sbjct: 544 CSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECA 603
Query: 737 ---------RVCQP----HGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGY---LC--L 778
R+C P H PQC+ S PC H D + G+ LC +
Sbjct: 604 PGFRGTTCQRICSPGFYGHRCSQTCPQCVH----SSGPCHHITGLCDCLPGFTGALCNEV 659
Query: 779 CSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSP- 837
C +G G +C C N G+C + + C+C G++G C P
Sbjct: 660 CPSGRFGKNC------AGICTCTNNGTCNPIDRS--CQCYPGWIGSDCSQPCPPAHWGPN 711
Query: 838 CQHGGRCESGG--GAY--LCVCPESFFGYHCETVSDPCFSSPCGGRG-----YCLASNG- 887
C H C +G AY C C + G +C + C P G G C NG
Sbjct: 712 CIHTCNCHNGAFCSAYDGECKCTPGWTGLYC---TQRC---PLGFYGKDCALICQCQNGA 765
Query: 888 -----SHSCTCKVGYTGEDCAKE 905
S CTC+ G+ G C ++
Sbjct: 766 DCDHISGQCTCRTGFMGRHCEQK 788
Score = 197 bits (501), Expect = 6e-50
Identities = 207/738 (28%), Positives = 267/738 (36%), Gaps = 158/738 (21%)
Query: 267 HTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCH------LDVNECASQ-P 319
H TS C C NG C + +TG C C +GF G RC N+C +
Sbjct: 147 HCTSRC----QCKNGALC--NPITG----ACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQ 196
Query: 320 CQNGGTCTHGINSFRCQCPAGFGGPTCETAQSP------CDTK-ECQHGGQCQVENGSAV 372
CQNG TC H C+CP G+ G CE P C+ + CQ+GG C G
Sbjct: 197 CQNGATCDHVTG--ECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGE-- 252
Query: 373 CVCQAGYTGAACEMDVDD------CSPD-PCLNGGSCVDLVGNYTCLCAEPFKGLRCE-- 423
C C +G+ G C + CS + C NGG+C G C C+ + G RC+
Sbjct: 253 CSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQ--CHCSPGYTGERCQDE 310
Query: 424 --TGDHPVPDACLSAPCHNGGTCVDADQGYVCE------------CPEGFMGLDCRERVP 469
G + V A + C NGG C +CE CPEG G+ C +R P
Sbjct: 311 CPVGTYGVLCA-ETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCP 369
Query: 470 DDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEIT----AMPCNMNTQCPDGGYCMEHGG 525
C N C + C C G+ GL C + C C +G C G
Sbjct: 370 --CHLENTHSCHPMSGE-CACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTG 426
Query: 526 SYLCVCHTDHNA-SHSLPSP-------CDSD-PCFNGGSCDAHDDSYTCECPRGFHGKHC 576
C C S P P C S C N C D S C C G+HG C
Sbjct: 427 K--CTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGS--CTCKAGWHGVDC 482
Query: 577 EKARPHLCSSG----------PCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASG 626
C SG C NGG C G C+C + G CE+ D
Sbjct: 483 SIR----CPSGTWGFGCNLTCQCLNGGACNTLDGT--CTCAPGWRGEKCELPCQDGTYGL 536
Query: 627 PCHNGGTCFHYIGKY----KCDCPPGFSGRHCEIAPS----------PCFRSPCVNGGTC 672
C C H G + C C PG+SG HC+ + PC+ C NG +C
Sbjct: 537 NCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCY---CKNGASC 593
Query: 673 EDRDTDFFCHCQAGYMGRRCQAEVDCGPP------EEVKHATLRFNGTRLGAVALYACDR 726
D C C G+ G CQ C P + + +G L C
Sbjct: 594 S--PDDGICECAPGFRGTTCQR--ICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLP 649
Query: 727 GYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQ--DRVAGYLCLCSTGYE 784
G++ + + VC P G + + C I C C + G+C DR C C G+
Sbjct: 650 GFTGALCN--EVC-PSGRFGK--NCAGI--C---TCTNNGTCNPIDR----SCQCYPGWI 695
Query: 785 GAHCELERDECRAHP-------CRNGGSCRNLPGAYVCRCPAGFVGVHCETEV------- 830
G+ C P C NG C G C+C G+ G++C
Sbjct: 696 GSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE--CKCTPGWTGLYCTQRCPLGFYGK 753
Query: 831 DACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGS-- 888
D CQ+G C+ G C C F G HCE P + G R C N S
Sbjct: 754 DCALICQCQNGADCDHISGQ--CTCRTGFMGRHCEQ-KCPSGTYGYGCRQICDCLNNSTC 810
Query: 889 ----HSCTCKVGYTGEDC 902
+C C G+ G C
Sbjct: 811 DHITGTCYCSPGWKGARC 828
Score = 193 bits (490), Expect = 1e-48
Identities = 195/718 (27%), Positives = 247/718 (34%), Gaps = 229/718 (31%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDV-------NECASQ-PCQNGGTCTHG 329
C NG C D VTG C C G+TG C D+ +C + PCQNGG C H
Sbjct: 197 CQNGATC--DHVTGE----CRCPPGYTGAFCE-DLCPPGKHGPQCEQRCPCQNGGVCHHV 249
Query: 330 INSFRCQCPAGFGGPTCETAQSPCD--------TKECQ--HGGQCQVENGSAVCVCQAGY 379
C CP+G+ G C PC ++ECQ +GG C G C C GY
Sbjct: 250 TGE--CSCPSGWMGTVCG---QPCPEGRFGKNCSQECQCHNGGTCDAATGQ--CHCSPGY 302
Query: 380 TGAACEMDVDDCSPDP----------CLNGGSCVDLVGNYTCLCAEPFKGLRCET----- 424
TG C+ D+C C+NGG C + G CLC F G RCE
Sbjct: 303 TGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHVSG--ACLCEAGFAGERCEARLCPE 357
Query: 425 -------------------GDHPVPDACLSAP-------------------------CHN 440
HP+ C P C N
Sbjct: 358 GLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQN 417
Query: 441 GGTCVDADQGYVCECPEGFMGLDCRERVP---------DDCECRNGGRCLGANTTLCQCP 491
G C D+ G C C GF G+DC P C C+N C + + C C
Sbjct: 418 GADC-DSVTGK-CTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGS-CTCK 474
Query: 492 LGFFGLLCEFEITA----MPCNMNTQCPDGGYCMEHGGSYLCV-------CHT---DHNA 537
G+ G+ C + CN+ QC +GG C G+ C C D
Sbjct: 475 AGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTY 534
Query: 538 SHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGP--------- 588
+ CD C + C H + C C G+ G HC+ +C+ G
Sbjct: 535 GLNCAERCD---CSHADGC--HPTTGHCRCLPGWSGVHCDS----VCAEGRWGPNCSLPC 585
Query: 589 -CRNGGTCKEAGGEYHCSCPYRFTG--RHCEIGKPDSCASGPC----HNGGTCFHYIGKY 641
C+NG +C G C+ +R T R C G S C H+ G C H G
Sbjct: 586 YCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGL- 644
Query: 642 KCDCPPGFSGRHC-EIAPSPCFRS------PCVNGGTCEDRDTDFFCHCQAGYMGRRCQA 694
CDC PGF+G C E+ PS F C N GTC D C C G++G
Sbjct: 645 -CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRS--CQCYPGWIGS---- 697
Query: 695 EVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEI 754
DC P H P+ I C H C
Sbjct: 698 --DCSQPCPPAHW------------------------GPNCIHTCNCHN----GAFCSAY 727
Query: 755 D-ECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAY 813
D EC+ P G C R C G+ G C L C+ C+NG C ++ G
Sbjct: 728 DGECKCTPGWTGLYCTQR-------CPLGFYGKDCALI---CQ---CQNGADCDHISGQC 774
Query: 814 VCR-----------CPAGFVGVHCETEVDACDSSPCQH------------GGRCESGG 848
CR CP+G G C D ++S C H G RC+ G
Sbjct: 775 TCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAG 832
Score = 189 bits (479), Expect = 2e-47
Identities = 198/704 (28%), Positives = 250/704 (35%), Gaps = 186/704 (26%)
Query: 299 CLSGF--TGRRCHLDVNECASQPCQNGGTCTHG--INSFRCQCPAGFGGPTCETAQSP-- 352
C GF +G C V CA + C HG I CQC G+GG C +A
Sbjct: 94 CCPGFYESGEMC---VPHCADK-------CVHGRCIAPNTCQCEPGWGGTNCSSACDGDH 143
Query: 353 ----CDTK-ECQHGGQCQVENGSAVCVCQAGYTGAACEMDVD------DCSPD-PCLNGG 400
C ++ +C++G C G+ C C AG+ G CE + DC C NG
Sbjct: 144 WGPHCTSRCQCKNGALCNPITGA--CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGA 201
Query: 401 SCVDLVGNYTCLCAEPFKGLRCET----GDHPVPDACLSAPCHNGGTCVDADQGYVCECP 456
+C + G C C + G CE G H P PC NGG C C CP
Sbjct: 202 TCDHVTGE--CRCPPGYTGAFCEDLCPPGKHG-PQCEQRCPCQNGGVCHHVTGE--CSCP 256
Query: 457 EGFMGLDCRERVPD---------DCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMP 507
G+MG C + P+ +C+C NGG C A T C C G+ G C+ E
Sbjct: 257 SGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTC-DAATGQCHCSPGYTGERCQDE----- 310
Query: 508 CNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCEC 567
CP G Y LC ++ C NGG C + S C C
Sbjct: 311 ------CPVGTY------GVLCA---------------ETCQCVNGGKC--YHVSGACLC 341
Query: 568 PRGFHGKHCEKARPHLCSSG----------PCR--NGGTCKEAGGEYHCSCPYRFTGRHC 615
GF G+ CE LC G PC N +C GE C+C ++G +C
Sbjct: 342 EAGFAGERCEA---RLCPEGLYGIKCDKRCPCHLENTHSCHPMSGE--CACKPGWSGLYC 396
Query: 616 EIGKPDSCASG----------PCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPC---- 661
++C+ G C NG C GK C C PGF G C +PC
Sbjct: 397 N----ETCSPGFYGEACQQICSCQNGADCDSVTGK--CTCAPGFKGIDCS---TPCPLGT 447
Query: 662 ------FRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTR 715
R C N C D C C+AG+ G C G T F
Sbjct: 448 YGINCSSRCGCKNDAVCSPVDGS--CTCKAGWHGVDCSIRCPSG--------TWGF---- 493
Query: 716 LGAVALYACDRGYSLSAPSRIRVCQP--HGVWSEPPQCLE----IDECRSQPCLHGGSCQ 769
G C G + + C P G E P C + ++ C H C
Sbjct: 494 -GCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELP-CQDGTYGLNCAERCDCSHADGCH 551
Query: 770 DRVAGYLCLCSTGYEGAHCELERDECRAHP-------CRNGGSCRNLPGAYVCR------ 816
C C G+ G HC+ E R P C+NG SC G C
Sbjct: 552 PTTGH--CRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGT 609
Query: 817 -----CPAGFVGVHCETEVDAC--DSSPCQH-GGRCES--GGGAYLC--VCPESFFGYHC 864
C GF G C C S PC H G C+ G LC VCP FG +C
Sbjct: 610 TCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNC 669
Query: 865 ETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
+ C G C + SC C G+ G DC++ P
Sbjct: 670 AGICT------CTNNGTCNPID--RSCQCYPGWIGSDCSQPCPP 705
Score = 151 bits (382), Expect = 4e-36
Identities = 136/474 (28%), Positives = 180/474 (37%), Gaps = 95/474 (20%)
Query: 266 GHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVN------ECASQ- 318
G C + C NG C D VTG C+C GF G C C+S+
Sbjct: 403 GFYGEACQQICSCQNGADC--DSVTGK----CTCAPGFKGIDCSTPCPLGTYGINCSSRC 456
Query: 319 PCQNGGTCTHGINSFRCQCPAGFGGPTCE------TAQSPCD-TKECQHGGQCQVENGSA 371
C+N C+ S C C AG+ G C T C+ T +C +GG C +G+
Sbjct: 457 GCKNDAVCSPVDGS--CTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGT- 513
Query: 372 VCVCQAGYTGAACEMDVDD------CSPD-PCLNGGSCVDLVGNYTCLCAEPFKGLRCET 424
C C G+ G CE+ D C+ C + C G+ C C + G+ C++
Sbjct: 514 -CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGH--CRCLPGWSGVHCDS 570
Query: 425 ---GDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRE---------RVPDDC 472
P+ L C NG +C D G +CEC GF G C+ R C
Sbjct: 571 VCAEGRWGPNCSLPCYCKNGASC-SPDDG-ICECAPGFRGTTCQRICSPGFYGHRCSQTC 628
Query: 473 -ECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC 531
+C + T LC C GF G LC N CP G + G +C C
Sbjct: 629 PQCVHSSGPCHHITGLCDCLPGFTGALC-----------NEVCPSGRFGKNCAG--ICTC 675
Query: 532 HTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRN 591
T++ + + C P + G C CP G +C H C+ C N
Sbjct: 676 -TNNGTCNPIDRSCQCYPGWIGSDCSQ-------PCPPAHWGPNCI----HTCN---CHN 720
Query: 592 GGTCKEAGGEYHCSCPYRFTGRHCEIGKP------DSCASGPCHNGGTCFHYIGKYKCDC 645
G C GE C C +TG +C P D C NG C H G+ C C
Sbjct: 721 GAFCSAYDGE--CKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQ--CTC 776
Query: 646 PPGFSGRHCE-IAPSPCFR------SPCVNGGTCEDRDTDFFCHCQAGYMGRRC 692
GF GRHCE PS + C+N TC+ C+C G+ G RC
Sbjct: 777 RTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCD--HITGTCYCSPGWKGARC 828
Score = 150 bits (378), Expect = 1e-35
Identities = 148/513 (28%), Positives = 183/513 (35%), Gaps = 139/513 (27%)
Query: 448 DQGYVCECPEGFMGLDC-RERVPDDCECRNGGRCLGANTTLCQCPLGFF--GLLCEFEIT 504
DQ Y C + C R RV R+G + + + C CP GF+ G +C
Sbjct: 53 DQIYYTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQC-CP-GFYESGEMCVPHCA 110
Query: 505 AMPCNMNTQCPDGGYCMEHGGSYLC--VCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDS 562
+ P+ C G C C DH H S C C NG C+ +
Sbjct: 111 DKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCT-SRCQ---CKNGALCNPITGA 166
Query: 563 YTCECPRGFHGKHCEKARPHLCSSGP----------CRNGGTCKEAGGEYHCSCPYRFTG 612
C C GF G CE C G C+NG TC GE C CP +TG
Sbjct: 167 --CHCAAGFRGWRCEDR----CEQGTYGNDCHQRCQCQNGATCDHVTGE--CRCPPGYTG 218
Query: 613 RHCEIGKPDSCASG----------PCHNGGTCFHYIGKYKCDCPPGFSGRHC-EIAPSPC 661
CE D C G PC NGG C H G+ C CP G+ G C + P
Sbjct: 219 AFCE----DLCPPGKHGPQCEQRCPCQNGGVCHHVTGE--CSCPSGWMGTVCGQPCPEGR 272
Query: 662 F------RSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTR 715
F C NGGTC+ CHC GY G RCQ E G
Sbjct: 273 FGKNCSQECQCHNGGTCDAATGQ--CHCSPGYTGERCQDECPVGT--------------- 315
Query: 716 LGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGY 775
G + C C++GG C V+G
Sbjct: 316 YGVLCAETCQ------------------------------------CVNGGKCY-HVSG- 337
Query: 776 LCLCSTGYEGAHCE-------LERDEC-RAHPCR--NGGSCRNLPGAYVCRCPAGFVGVH 825
CLC G+ G CE L +C + PC N SC + G C C G+ G++
Sbjct: 338 ACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGE--CACKPGWSGLY 395
Query: 826 CETEV------DACDS-SPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPC------- 871
C +AC CQ+G C+S G C C F G C T PC
Sbjct: 396 CNETCSPGFYGEACQQICSCQNGADCDSVTGK--CTCAPGFKGIDCST---PCPLGTYGI 450
Query: 872 -FSSPCGGRGYCLASNGSHSCTCKVGYTGEDCA 903
SS CG + + S SCTCK G+ G DC+
Sbjct: 451 NCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCS 483
Score = 103 bits (257), Expect = 1e-21
Identities = 122/449 (27%), Positives = 152/449 (33%), Gaps = 98/449 (21%)
Query: 497 LLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDS------DPC 550
LLC + TA P N+ D C H SY S P P D
Sbjct: 15 LLCHWIGTASPLNLE----DPNVC-SHWESYSVT------VQESYPHPFDQIYYTSCTDI 63
Query: 551 FNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRF 610
N C H SY HG+ R C G +G C HC+
Sbjct: 64 LNWFKCTRHRVSYRTAYR---HGEKTMYRRKSQCCPGFYESGEMCVP-----HCA----- 110
Query: 611 TGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIA-------PSPCFR 663
D C G C I C C PG+ G +C A P R
Sbjct: 111 ----------DKCVHGRC---------IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSR 151
Query: 664 SPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRF-NGTRLGAV-AL 721
C NG C CHC AG+ G RC+ + G H + NG V
Sbjct: 152 CQCKNGALC--NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE 209
Query: 722 YACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCST 781
C GY+ + + HG PQC + C PC +GG C V G C C +
Sbjct: 210 CRCPPGYTGAFCEDLCPPGKHG-----PQCEQ--RC---PCQNGGVCH-HVTGE-CSCPS 257
Query: 782 GYEGAHCELERDECR-------AHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETE----- 829
G+ G C E R C NGG+C G C C G+ G C+ E
Sbjct: 258 GWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQ--CHCSPGYTGERCQDECPVGT 315
Query: 830 --VDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDP--CFSSPCGGRGYCLAS 885
V ++ C +GG+C GA C+C F G CE P + C R C
Sbjct: 316 YGVLCAETCQCVNGGKCYHVSGA--CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLE 373
Query: 886 NG------SHSCTCKVGYTGEDCAKELFP 908
N S C CK G++G C + P
Sbjct: 374 NTHSCHPMSGECACKPGWSGLYCNETCSP 402
Score = 41.6 bits (96), Expect = 0.005
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 8/61 (13%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIK--VSRPCTRLFSETKAFPVWEGGVCHH 1373
C+NG +C P D C+C PGF+G C+ C C S+T V G CHH
Sbjct: 587 CKNGASCSP--DDGICECAPGFRGTTCQRICSPGFYGHRC----SQTCPQCVHSSGPCHH 640
Query: 1374 V 1374
+
Sbjct: 641 I 641
Score = 41.2 bits (95), Expect = 0.007
Identities = 27/71 (38%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 1305 GNVPGNCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAF 1363
G NCS+ C NGGTC A C C PG+ G RC+ C + L +ET
Sbjct: 271 GRFGKNCSQECQCHNGGTC--DAATGQCHCSPGYTGERCQDECPVGTYGV--LCAET--C 324
Query: 1364 PVWEGGVCHHV 1374
GG C+HV
Sbjct: 325 QCVNGGKCYHV 335
Score = 40.0 bits (92), Expect = 0.016
Identities = 28/75 (37%), Positives = 32/75 (42%), Gaps = 15/75 (20%)
Query: 1305 GNVPGNCSEN-PCQNGGTC--VPGADAHSCDCGPGFKGRRCELACI--KVSRPCTRLFSE 1359
G +C + CQNG TC V G C C PG+ G CE C K C
Sbjct: 185 GTYGNDCHQRCQCQNGATCDHVTG----ECRCPPGYTGAFCEDLCPPGKHGPQC------ 234
Query: 1360 TKAFPVWEGGVCHHV 1374
+ P GGVCHHV
Sbjct: 235 EQRCPCQNGGVCHHV 249
Score = 35.8 bits (81), Expect = 0.30
Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 2/31 (6%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
C NGG C +C C PG++G +CEL C
Sbjct: 501 CLNGGAC--NTLDGTCTCAPGWRGEKCELPC 529
Score = 34.3 bits (77), Expect = 0.87
Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 2/39 (5%)
Query: 1308 PGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
P S C+NG C P A C C GF+G RCE C
Sbjct: 146 PHCTSRCQCKNGALCNPITGA--CHCAAGFRGWRCEDRC 182
Score = 33.5 bits (75), Expect = 1.5
Identities = 16/35 (45%), Positives = 17/35 (48%), Gaps = 4/35 (11%)
Query: 1316 CQNGGTCVPGADAHS----CDCGPGFKGRRCELAC 1346
CQ +C GAD S C C PGFKG C C
Sbjct: 409 CQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPC 443
Score = 32.7 bits (73), Expect = 2.5
Identities = 24/80 (30%), Positives = 27/80 (33%), Gaps = 19/80 (23%)
Query: 1306 NVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV--------------SR 1351
N G C+ C N GTC P SC C PG+ G C C
Sbjct: 668 NCAGICT---CTNNGTCNP--IDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGA 722
Query: 1352 PCTRLFSETKAFPVWEGGVC 1371
C+ E K P W G C
Sbjct: 723 FCSAYDGECKCTPGWTGLYC 742
Score = 31.6 bits (70), Expect = 5.6
Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 25/112 (22%)
Query: 1311 CSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCE----------LAC-------IKVSRP 1352
C+E C NGG C + A C C GF G RCE + C ++ +
Sbjct: 320 CAETCQCVNGGKCYHVSGA--CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS 377
Query: 1353 CTRLFSETKAFPVWEGGVCHHVYKRVY--RVHQDICFKES---CESTSLKKT 1399
C + E P W G C+ + Q IC ++ C+S + K T
Sbjct: 378 CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCT 429
Score = 31.6 bits (70), Expect = 5.6
Identities = 14/31 (45%), Positives = 15/31 (48%), Gaps = 2/31 (6%)
Query: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
CQNG C + C C GF GR CE C
Sbjct: 761 CQNGADC--DHISGQCTCRTGFMGRHCEQKC 789
Score = 31.2 bits (69), Expect = 7.4
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 10/58 (17%)
Query: 1299 HGSKDIGNVPGNCSENPCQNGGTCVPG-ADA---------HSCDCGPGFKGRRCELAC 1346
HG K + C ++G CVP AD ++C C PG+ G C AC
Sbjct: 82 HGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSAC 139
Score = 30.8 bits (68), Expect = 9.6
Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 6/51 (11%)
Query: 1316 CQNGGTC--VPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFP 1364
C N TC + G +C C PG+KG RC+ A + + L + A P
Sbjct: 804 CLNNSTCDHITG----TCYCSPGWKGARCDQAGVIIVGNLNSLSRTSTALP 850
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 197 bits (501), Expect = 6e-50
Identities = 202/742 (27%), Positives = 288/742 (38%), Gaps = 134/742 (18%)
Query: 272 CLALRPC-LNGGKCIDDCVTGNPSYTCSCLSGFT----GRRCHLDVNECASQP--CQNGG 324
C+ + C + G C C+ SY CSC G++ GR C DV+EC P C G
Sbjct: 1153 CVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRAC-ADVDECEENPRVCDQ-G 1210
Query: 325 TCTHGINSFRCQCPAGF-GGPTCETA--QSPCDTKE--CQHGGQCQVENGSAVCVCQAGY 379
CT+ RC C GF P T CD C H G C+ GS VC CQ GY
Sbjct: 1211 HCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLH-GDCENTKGSFVCHCQLGY 1269
Query: 380 ---TGAACEMDVDDC--SPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACL 434
GA DVD+C C + SC+++ G+++C C + G E D D C+
Sbjct: 1270 MVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHD---LDECV 1326
Query: 435 SAP--CHNGGTCVDADQGYVCECPEGFMG----LDCRERVPDDCECRNGGRCLGA-NTTL 487
S C G C++ Y C C +GF G + R+ ++ + + G+CL A
Sbjct: 1327 SQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYR 1386
Query: 488 CQCPLGFFGLLCEFEITAMPCNMNTQCPDG-----GYCMEHGGSYLCVCHTDHNASHSLP 542
C+C +GF + C +C G G C G + C+C+ +
Sbjct: 1387 CECEMGF-----DPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGG 1441
Query: 543 SPCDSDPCFN-----GGSCDAHDDSYTCECPRGFH----GKHCEKARPHLC---SSGPCR 590
+ D + C + G C SY C CP+ F G C R C +
Sbjct: 1442 NCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGD 1501
Query: 591 NGGTCKEAGG----EYHCSCPY-RFTGRHCE----------------------------I 617
+G +C G C C R G CE +
Sbjct: 1502 SGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVIL 1561
Query: 618 GKPDSCASGP-CHNGGTCFHYIGKYKCDCPPGF----SGRHCEIAPSPCFRSPCVNGGTC 672
D C P GG C + G ++C+CPPG+ R CE S GTC
Sbjct: 1562 EDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTC 1621
Query: 673 EDRDTDFFCHCQAGYM----GRRCQAEVDCGPPEEVKHAT------LRFNGTR------- 715
+ ++ C C A Y+ G C +D +H L FN TR
Sbjct: 1622 YNTLGNYTCVCPAEYLQVNGGNNC---MDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSY 1678
Query: 716 -LGAVALYACDRGYSLSAPSRIRVC--QPHGVWSE--PPQCLEIDECRSQPCL-HGGSCQ 769
+G C+ + +P +C Q G ++ + L+IDEC P + G C
Sbjct: 1679 NIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICI 1738
Query: 770 DRVAGYLCLCSTGYEG----AHCELERDEC--RAHPCRNGGSCRNLPGAYVCRCPAGF-- 821
+++ + C C G+ CE + DEC R PC+ C N+PG+Y C+C G+
Sbjct: 1739 NQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL 1797
Query: 822 -VGVHCETEVDACDSSP--CQHGGRCESGGGAYLCVCPESFFGYHCETVS---DPCFSSP 875
G C + C P C HG C G+Y+C+C F +T+ D C P
Sbjct: 1798 SPGGACVGR-NECREIPNVCSHGD-CMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP 1855
Query: 876 CGGRGYCLASNGSHSCTCKVGY 897
C G G C GS++C C G+
Sbjct: 1856 C-GNGTCKNIIGSYNCLCFPGF 1876
Score = 194 bits (493), Expect = 5e-49
Identities = 218/827 (26%), Positives = 303/827 (36%), Gaps = 231/827 (27%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTG--RRCHLDVNECASQPCQN 322
C H T++CL R C+ SY C C G+T R +DV+EC S PC +
Sbjct: 412 CRHFTNLCLNGR-----------CLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHH 460
Query: 323 GGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKEC------QHGGQCQVENGSAVCVCQ 376
G C + ++ C+C GF T Q+ D EC H G+C GS CVC
Sbjct: 461 -GDCVNIPGTYHCRCYPGF--QATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 377 AGY----TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPF----KGLRC-ETGDH 427
AG+ G C +D ++C+ G C++ G+++CLC F G C + +
Sbjct: 518 AGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC 576
Query: 428 PVPDACLSAPCHN----------GGTCVDADQGYVC-------ECPEGFMGLDCRERVP- 469
P C++ C N GG V D G VC C C P
Sbjct: 577 QTPGICVNGHCTNTEGSFRCQCLGGLAVGTD-GRVCVDTHVRSTCYGAIEKGSCARPFPG 635
Query: 470 ----DDCECRNGGRCLGANTTLCQC-PLGFFGLLCEFEI-------TAMPCNMNTQCPDG 517
+C C N G LC F LC + C ++ +
Sbjct: 636 TVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCAN 695
Query: 518 GYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPC------FNGGSCDAHDDSYTCECPRGF 571
G C GSY CVC+ + A S D D C + G C SY+C CP GF
Sbjct: 696 GVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGF 755
Query: 572 H----GKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCP-------------------- 607
H + C+ C S PC + G C+ G Y C C
Sbjct: 756 HFWQDTEICKDVDE--CLSSPCVS-GVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTC 812
Query: 608 -YRFTGRHCEIG------KPDSCAS------GPCH---------------NGGTC----- 634
+ CE+ + + CA+ PC G TC
Sbjct: 813 WLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNE 872
Query: 635 -------------FHYIGKYKCDCPPGF----SGRHC-EIAPSPCF----RSPCVNGGTC 672
+ G ++C+CP G SGR C ++ PCF C G T
Sbjct: 873 CESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDEC--GVTL 930
Query: 673 EDRDTDFFCHCQAGYM-GRRCQAEVDCGPPEEVKHAT----------------------- 708
+ C C G + G C+A C PE ++ A+
Sbjct: 931 PGKYRMDVCCCSIGAVWGVECEA---CPDPESLEFASLCPRGLGFASRDFLSGRPFYKDV 987
Query: 709 --------LRFNGTRLGAVALY--ACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECR 758
L +GT V + AC G++L A R C +IDECR
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER--------------NCTDIDECR 1033
Query: 759 SQPCLHG-GSCQDRVAGYLCLCSTGYEGA-----HCELERDECRAHP--CRNGGSCRNLP 810
P L G G+C + + C C GYE +C ++ DEC P CR GG+C N
Sbjct: 1034 ISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNC-MDVDECARDPLLCR-GGTCTNTD 1091
Query: 811 GAYVCRCPAGF----VGVHCETEVDACDSSP--CQHGGRCESGGGAYLCVCPESFFG--- 861
G+Y C+CP G G CE ++D C S C H G+C + GA+ C C F
Sbjct: 1092 GSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPH-GQCVNVIGAFQCSCHAGFQSTPD 1149
Query: 862 -YHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYT----GEDCA 903
C +++ C G +C+ + GS+ C+C GY+ G CA
Sbjct: 1150 RQGCVDINE-CRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACA 1195
Score = 186 bits (471), Expect = 2e-46
Identities = 223/836 (26%), Positives = 300/836 (35%), Gaps = 208/836 (24%)
Query: 262 VGGCGHTTSVCLALRPCLN-----------------GGKCID--------------DCVT 290
V CG S C C+N GG C+ DC+
Sbjct: 1764 VDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMD 1823
Query: 291 GNPSYTCSCLSGFTG---RRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCE 347
SY C C GF + +D++EC QPC NG TC + I S+ C C GF
Sbjct: 1824 TEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGF----VV 1878
Query: 348 TAQSPC-DTKECQ-------HGGQCQVENGSAVCVCQAGYT----GAACEMDVDDCSP-- 393
T C D EC G C GS C+CQ G+ G C +D ++C
Sbjct: 1879 THNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLA 1937
Query: 394 DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVP-DACLSAP--CHNGGTCVDADQG 450
CL G +C +L G++ C+C F+ DH + D C P C G TC ++
Sbjct: 1938 GTCLPG-TCQNLEGSFRCICPPGFQ----VQSDHCIDIDECSEEPNLCLFG-TCTNSPGS 1991
Query: 451 YVCECPEGFM----GLDCRERVPDDCECR-NGGRCL---GANTTLCQCPLG--------- 493
+ C CP GF+ G C + C R G+C NTT +C
Sbjct: 1992 FQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGD 2051
Query: 494 -----------FFGLLCEFEITAMP-----------CNMNTQCPDGGYCMEHGGSYLCVC 531
F LC F A+P C N G C+ GS+ C C
Sbjct: 2052 PCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCEC 2111
Query: 532 HTDHNASHSLPSPCDSDPCFNG-----GSCDAHDDSYTCECPRGFHG---KHCEKARPHL 583
++ + + D+D C G G+C + C C GF CE
Sbjct: 2112 PFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDE-- 2169
Query: 584 CSSGPCRNGGTCKEAGGEYHCSCPYRFT----GRHCEIGKPDSCASGP--CH-NGGTCFH 636
CS P C G Y C+CP +T G C D CA G CH G C +
Sbjct: 2170 CSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR--DVDECADGQQDCHARGMECKN 2227
Query: 637 YIGKYKCDCPPGF-----------SGRHCEIAPSPCFRSPCVN--GGTCEDRDTDFF--- 680
IG + C CPPG C P C CVN G D D F
Sbjct: 2228 LIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSP 2287
Query: 681 ----CH------CQAGYMGRRCQ-----------AEVDCGP-------------PEEVKH 706
CH C A + C+ AE CG P +
Sbjct: 2288 TLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAY 2347
Query: 707 ATLRFNGTRLGA---------VALYACDRGYSLSAPSRIRV-CQP-HGVWSEPPQCLEID 755
L +G+ A + + C G +++ R CQ + + CL++D
Sbjct: 2348 RKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 756 ECRSQPCLHGGSCQDRVAGYLCLCSTGY----EGAHCELERDEC--RAHPCRNGGSCRNL 809
EC P C++ +LC C GY +G C+ + DEC R H C+ C N
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQF--LCVNT 2464
Query: 810 PGAYVCRCPAGFVGVHCET-EVDACDS--SPCQHGGRCESGGGAYLCVCPESF----FGY 862
GA+ CRCP GF H + D C + PC G C + G++ C C + F G+
Sbjct: 2465 VGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGH 2524
Query: 863 HCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGE----DCAKE----LFPPT 910
CE V++ P + C G + C+C G+T C E L PPT
Sbjct: 2525 GCEDVNE--CDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPT 2578
Score = 186 bits (471), Expect = 2e-46
Identities = 177/627 (28%), Positives = 238/627 (37%), Gaps = 126/627 (20%)
Query: 256 DDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSG----FTGRRCHLD 311
DD++ V C VC NG CV + S+ C C G FTG C +D
Sbjct: 2079 DDSREDVNECAENPGVCT------NGV-----CVNTDGSFRCECPFGYSLDFTGINC-VD 2126
Query: 312 VNECA-SQPCQNGGTCTHGINSFRCQCPAGFGGP---TCETAQSPCDTKECQHGGQCQVE 367
+EC+ PC G TCT+ I F C C GF TCE C +C
Sbjct: 2127 TDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMTCEDIDE-CSLNPLLCAFRCHNT 2184
Query: 368 NGSAVCVCQAGYT----GAACEMDVDDCSP---DPCLNGGSCVDLVGNYTCLCAE----- 415
GS +C C AGYT GA C DVD+C+ D G C +L+G + C+C
Sbjct: 2185 EGSYLCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPL 2243
Query: 416 PFKGLRCETGD--HPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMG----LDCRERVP 469
P G C + H PD C++ G CV+ + C+C EGF +C +
Sbjct: 2244 PGSGEGCTDDNECHAQPDLCVN------GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 2297
Query: 470 DDC-------ECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQ--CPDG-GY 519
C CR+ A T C G G E+ +P + CP G GY
Sbjct: 2298 GPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGY 2357
Query: 520 CMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKA 579
E D + L C C N S+ C C G+
Sbjct: 2358 TAEG---------RDVDECRMLAHLCAHGECINSLG------SFRCHCQAGYTPDATATT 2402
Query: 580 RPHL--CSSGPCRNGGTCKEAGGEYHCSCPYRFT----GRHCEIGKPDSCASGPCHNGGT 633
+ CS P CK G + CSCP + GR C+ D C S +
Sbjct: 2403 CLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK--DLDECTSRQHNCQFL 2460
Query: 634 CFHYIGKYKCDCPPGFSGRH--------CEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQA 685
C + +G + C CPPGF+ H C P PC G C + F C C
Sbjct: 2461 CVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAH-----GHCHNTPGSFRCECHQ 2515
Query: 686 GYM----GRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQP 741
G+ G C+ +C P +H G GY S P
Sbjct: 2516 GFTLVSSGHGCEDVNECDGPHRCQHGCQNQLG-------------GYRCSCPQGFT---Q 2559
Query: 742 HGVWSEPPQCLEIDECR-SQPCLHGGSCQDRVAGYLCLCSTGYEGAH----CELERDEC- 795
H W+ QC++ +EC S P SC++ + G+ C+C +G++ C+ E DEC
Sbjct: 2560 HSQWA---QCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ-EVDECA 2615
Query: 796 -RAHPCRNGGSCRNLPGAYVCRCPAGF 821
R PC SC N PG ++C CP G+
Sbjct: 2616 GRRGPCSY--SCANTPGGFLCGCPQGY 2640
Score = 184 bits (466), Expect = 7e-46
Identities = 199/751 (26%), Positives = 286/751 (38%), Gaps = 150/751 (19%)
Query: 268 TTSVCLALRPCLNGGKCIDDC-VTGNPSYTCSCLSGFTGRRCHLDVNECASQP--CQNGG 324
T S C P G+ C + + C SG D+NECA P C NG
Sbjct: 638 TKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANG- 696
Query: 325 TCTHGINSFRCQC----PAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY- 379
C + S+RC C AG G C G CQ GS C C G+
Sbjct: 697 VCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFH 756
Query: 380 ---TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTC-------------LCAEPFKGL--- 420
C+ DVD+C PC++G C +L G+YTC C + KG
Sbjct: 757 FWQDTEICK-DVDECLSSPCVSG-VCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWL 814
Query: 421 -----RCETGDHPVPDACLSAPCHNGGTCVDADQGYVCE-------CPEGFM---GLDCR 465
RCE + A L + C + A G CE C GF G+ C
Sbjct: 815 KIQESRCEVN---LQGASLRSECC---ATLGAAWGSPCERCEIDPACARGFARMTGVTCD 868
Query: 466 ERVPDDCECRNG----GRCLG-ANTTLCQCPLGFF----GLLCEFEITAMPCNMNTQCPD 516
+ ++CE G GRC+ A + C+CP G G LC ++ PC + +
Sbjct: 869 D--VNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC-VDVRLEPCFLRWDEDE 925
Query: 517 GGYCMEHGGSY-LCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCE----CPRG- 570
G + G Y + VC C S G C+A D + E CPRG
Sbjct: 926 CGVTLP--GKYRMDVC-------------CCSIGAVWGVECEACPDPESLEFASLCPRGL 970
Query: 571 -FHGKHCEKARPHLCSSGPCR------NGGTCKEAGGEYHCSCPYRFT----GRHCEIGK 619
F + RP C+ GTC+ G +HC+C F R+C
Sbjct: 971 GFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCT--D 1028
Query: 620 PDSCASGPCHNG-GTCFHYIGKYKCDCPPGFSG-----RHCEIAPSPCFRSPCV-NGGTC 672
D C P G GTC + G ++C+C PG+ ++C + C R P + GGTC
Sbjct: 1029 IDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNC-MDVDECARDPLLCRGGTC 1087
Query: 673 EDRDTDFFCHCQAGY----MGRRCQAEVDCGPPEEVK----------------HATLRFN 712
+ D + C C G+ G C+ +C + + HA +
Sbjct: 1088 TNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQST 1147
Query: 713 GTRLGAVALYACD--------RGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCL- 763
R G V + C + R Q + + + C ++DEC P +
Sbjct: 1148 PDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVC 1207
Query: 764 HGGSCQDRVAGYLCLCSTGYEGA---HCELERDECRAHP--CRNGGSCRNLPGAYVCRCP 818
G C + G+ CLC G+ ++ DEC +P C +G C N G++VC C
Sbjct: 1208 DQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHG-DCENTKGSFVCHCQ 1266
Query: 819 AGFV---GVHCETEVDACD--SSPCQHGGRCESGGGAYLCVCPESFFG--YHCETVSDPC 871
G++ G ++VD C+ C C + G++ C C + G + C + D C
Sbjct: 1267 LGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL-DEC 1325
Query: 872 FSSP--CGGRGYCLASNGSHSCTCKVGYTGE 900
S C RG CL GS+ CTC+ G+ G+
Sbjct: 1326 VSQEHRCSPRGDCLNVPGSYRCTCRQGFAGD 1356
Score = 182 bits (463), Expect = 2e-45
Identities = 203/739 (27%), Positives = 286/739 (38%), Gaps = 162/739 (21%)
Query: 245 VGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRP-CLNGGKCIDDCVTGNPSYTCSCLSGF 303
+ +PG ++ R V G H C++ C G C++ V G SY C+C GF
Sbjct: 1298 LNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLN--VPG--SYRCTCRQGF 1353
Query: 304 TGRR--CHLDVNECASQP--CQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQ 359
G C D +ECA C N G C + +RC+C GF PT E ++ D EC
Sbjct: 1354 AGDGFFCE-DRDECAENVDLCDN-GQCLNAPGGYRCECEMGF-DPT-EDHRACQDVDECA 1409
Query: 360 HG-----GQCQVENGSAVCVCQAGYT----GAACEMDVDDCS-PDPCLNGGSCVDLVGNY 409
G G C+ G C+C GY G C D+++C+ P C+N G C++ G+Y
Sbjct: 1410 QGNLCAFGSCENLPGMFRCICNGGYELDRGGGNC-TDINECADPVNCIN-GVCINTPGSY 1467
Query: 410 TCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQG--YVCECPEGFMGLDCRER 467
C C + F+ +P +G CVD G ++ G G+ C
Sbjct: 1468 LCSCPQDFE-------LNP-----------SGVGCVDTRAGNCFLETHDRGDSGISCSAE 1509
Query: 468 VPDDCECRNGGRCLGANTTLCQCPLG-FFGLLCEFEITAMPCNMNTQCPDG-GYCMEHGG 525
+ +G C C LG +G CE A T CP G G+
Sbjct: 1510 IG-----------VGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGF----QP 1554
Query: 526 SYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFH-GKH---CEKARP 581
+ + V D + LP C GG C S+ CECP G+H +H CE
Sbjct: 1555 NRITVILEDIDECQELPGLC------QGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDE 1608
Query: 582 HLCSSGPCRNGGTCKEAGGEYHCSCPYRFT----GRHCEIGKPDSCASGPCHNGGTCFHY 637
SG C GTC G Y C CP + G +C + C H GTC +
Sbjct: 1609 CSTHSGIC-GPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFR---HYNGTCQNE 1664
Query: 638 IG----KYKCDCPPGFS---GRHCEIAPSP------------------------------ 660
+ + C C R CE P+P
Sbjct: 1665 LAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDE 1724
Query: 661 CFRSP--CVNGGTCEDRDTDFFCHCQAGY----MGRRCQAEVDCGPPEEVKHATLRFNGT 714
C P C N G C ++ F C C AG+ + C+ +CG E + + N
Sbjct: 1725 CGEIPAICAN-GICINQIGSFRCECPAGFNYNSILLACEDVDECGSRE----SPCQQNAD 1779
Query: 715 RLGAVALY--ACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP--CLHGGSCQD 770
+ Y C RGY LS P G C+ +ECR P C H G C D
Sbjct: 1780 CINIPGSYRCKCTRGYKLS---------PGGA------CVGRNECREIPNVCSH-GDCMD 1823
Query: 771 RVAGYLCLCSTGYEGAHCE---LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVH-- 825
Y+CLC G++ + + ++ DEC PC N G+C+N+ G+Y C C GFV H
Sbjct: 1824 TEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN-GTCKNIIGSYNCLCFPGFVVTHNG 1882
Query: 826 -CETEVDACDSSPCQ--HGGRCESGGGAYLCVCPESF----FGYHCETVSDPCFSSPCGG 878
C + D C + Q G C + G++ C+C + F G +C ++ +
Sbjct: 1883 DC-VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCL 1941
Query: 879 RGYCLASNGSHSCTCKVGY 897
G C GS C C G+
Sbjct: 1942 PGTCQNLEGSFRCICPPGF 1960
Score = 181 bits (458), Expect = 6e-45
Identities = 186/686 (27%), Positives = 245/686 (35%), Gaps = 162/686 (23%)
Query: 304 TGRRCHLDVNECASQPCQNGGTCTHG-----INSFRCQCPAGFGGPTCETAQSPCDTKEC 358
+GR + DVNEC P G CTHG + SF C C GF E ++ D EC
Sbjct: 979 SGRPFYKDVNECKVFP----GLCTHGTCRNTVGSFHCACAGGFALDAQE--RNCTDIDEC 1032
Query: 359 QHG------GQCQVENGSAVCVCQAGYTGAACEM----DVDDCSPDPCL-NGGSCVDLVG 407
+ G C GS C C GY M DVD+C+ DP L GG+C + G
Sbjct: 1033 RISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDG 1092
Query: 408 NYTCLCAE----PFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLD 463
+Y C C KG CE + + LS G CV+ + C C GF
Sbjct: 1093 SYKCQCPPGHELTAKGTACE----DIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTP 1148
Query: 464 CRERVPDDCECR--NGG---RCLGANTTL-CQCPLGFF----GLLCEFEITAMPCNMNTQ 513
R+ D ECR NGG C+ + C C G+ G C C N +
Sbjct: 1149 DRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRAC---ADVDECEENPR 1205
Query: 514 CPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNG------GSCDAHDDSYTCEC 567
D G+C G + C+C+ A+ + + D D C G C+ S+ C C
Sbjct: 1206 VCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHC 1265
Query: 568 PRGFHGKH----CEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSC 623
G+ + C C + +C G + C C + G E D C
Sbjct: 1266 QLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDEC 1325
Query: 624 ASGP--CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFC 681
S C G C + G Y+C C GF+G +G CEDRD
Sbjct: 1326 VSQEHRCSPRGDCLNVPGSYRCTCRQGFAG----------------DGFFCEDRD----- 1364
Query: 682 HCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQP 741
C VD L NG L A Y C+ R CQ
Sbjct: 1365 ---------ECAENVD-----------LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQ- 1403
Query: 742 HGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE----GAHCELERDECRA 797
++DEC GSC++ + C+C+ GYE G +C + +EC A
Sbjct: 1404 -----------DVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNC-TDINEC-A 1450
Query: 798 HP--CRNGGSCRNLPGAYVCRCPAGF--------------------------VGVHCETE 829
P C N G C N PG+Y+C CP F G+ C E
Sbjct: 1451 DPVNCIN-GVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAE 1509
Query: 830 V-------DACDSSPCQHGGRCE----SGGGAYLCVCP--ESFFGYHCETV---SDPCFS 873
+ C S G CE + Y +CP E F + D C
Sbjct: 1510 IGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQE 1569
Query: 874 SP--CGGRGYCLASNGSHSCTCKVGY 897
P C G G C+ + GS C C GY
Sbjct: 1570 LPGLCQG-GDCVNTFGSFQCECPPGY 1594
Score = 174 bits (440), Expect = 7e-43
Identities = 183/612 (29%), Positives = 243/612 (39%), Gaps = 110/612 (17%)
Query: 310 LDVNECASQP--CQNGGTCTHGINSFRCQCPAGFGGPT----CETAQSPCDTKE--CQHG 361
LD++EC P C NG C + I SFRC+CPAGF + CE C ++E CQ
Sbjct: 1720 LDIDECGEIPAICANG-ICINQIGSFRCECPAGFNYNSILLACEDVDE-CGSRESPCQQN 1777
Query: 362 GQCQVENGSAVCVCQAGY---TGAACEMDVDDCS--PDPCLNGGSCVDLVGNYTCLCAEP 416
C GS C C GY G AC + ++C P+ C + G C+D G+Y CLC
Sbjct: 1778 ADCINIPGSYRCKCTRGYKLSPGGAC-VGRNECREIPNVC-SHGDCMDTEGSYMCLCHRG 1835
Query: 417 FKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFM---GLDCRERVPDDCE 473
F+ +T + D C PC N GTC + Y C C GF+ DC + D+C
Sbjct: 1836 FQASADQTLCMDI-DECDRQPCGN-GTCKNIIGSYNCLCFPGFVVTHNGDCVDF--DECT 1891
Query: 474 CRNGGRCLGANTTLCQCPLGFFGLLCE--FEITA--MPCNMNTQCPD------GGYCMEH 523
G C + C G F LC+ FE+TA C +C G C
Sbjct: 1892 TLVGQVCRFGH---CLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNL 1948
Query: 524 GGSYLCVCHTDH--NASHSLP-SPCDSDP--CFNGGSCDAHDDSYTCECPRGF----HGK 574
GS+ C+C + H + C +P C G+C S+ C CP GF +G
Sbjct: 1949 EGSFRCICPPGFQVQSDHCIDIDECSEEPNLCL-FGTCTNSPGSFQCLCPPGFVLSDNGH 2007
Query: 575 HCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFT---GRHCEIGKPDSCASGPC--- 628
C R C T EAG CS P F R C +P PC
Sbjct: 2008 RCFDTRQSFCF--------TRFEAG---KCSVPKAFNTTKTRCCCSKRPGEGWGDPCELC 2056
Query: 629 -HNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSP--CVNGGTCEDRDTDFFCHCQA 685
G F + + PG ++ + C +P C N G C + D F C C
Sbjct: 2057 PQEGSAAFQELCPFGHGAVPGPDDSREDV--NECAENPGVCTN-GVCVNTDGSFRCECPF 2113
Query: 686 GY----MGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQP 741
GY G C +C V H + T + AC G+ P + C+
Sbjct: 2114 GYSLDFTGINCVDTDEC----SVGHPCGQGTCTNVIGGFECACADGFE---PGLMMTCE- 2165
Query: 742 HGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGY----EGAHCELERDECR- 796
+IDEC P L C + YLC C GY +GA C + DEC
Sbjct: 2166 -----------DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECAD 2213
Query: 797 -AHPCR-NGGSCRNLPGAYVCRCPAGF-----VGVHCETEVDACDSSP--CQHGGRCESG 847
C G C+NL G + C CP G G C T+ + C + P C + GRC +
Sbjct: 2214 GQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC-TDDNECHAQPDLCVN-GRCVNT 2271
Query: 848 GGAYLCVCPESF 859
G++ C C E F
Sbjct: 2272 AGSFRCDCDEGF 2283
Score = 161 bits (407), Expect = 5e-39
Identities = 180/700 (25%), Positives = 259/700 (37%), Gaps = 143/700 (20%)
Query: 280 NGGKCIDD----CVTGNPSYTCSCLSGF--TGRRCHLDVNECASQPCQN-GGTCT----H 328
NG +C D C T + CS F T RC C+ +P + G C
Sbjct: 2005 NGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCC-----CSKRPGEGWGDPCELCPQE 2059
Query: 329 GINSFRCQCPAGFG---GPTCETAQSPCDTKECQHG------GQCQVENGSAVCVCQAGY 379
G +F+ CP G G GP S D EC G C +GS C C GY
Sbjct: 2060 GSAAFQELCPFGHGAVPGPD----DSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGY 2115
Query: 380 ----TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFK-GLRCETGDHPVPDACL 434
TG C +D D+CS G+C +++G + C CA+ F+ GL D D C
Sbjct: 2116 SLDFTGINC-VDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDI---DECS 2171
Query: 435 SAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGF 494
P C + + Y+C CP G+ + D EC +G + A C+ +G
Sbjct: 2172 LNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGT 2231
Query: 495 FGLLCEFEITAMP-----CNMNTQC---PD---GGYCMEHGGSYLCVCHTDHNASHSLPS 543
F +C + +P C + +C PD G C+ GS+ C C S +L
Sbjct: 2232 FACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTE 2291
Query: 544 PCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCK----EAG 599
D G C A C R R C G G C+
Sbjct: 2292 CHD----IRQGPCFAEVLQTMC---RSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGT 2344
Query: 600 GEYHCSCPYRFTGRHCEIGKPDSCA--SGPCHNGGTCFHYIGKYKCDCPPGFSGR----- 652
Y CP+ +G E D C + C +G C + +G ++C C G++
Sbjct: 2345 SAYRKLCPHG-SGYTAEGRDVDECRMLAHLCAHG-ECINSLGSFRCHCQAGYTPDATATT 2402
Query: 653 -----HCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYM----GRRCQAEVDCG---- 699
C P PC C++ F C C GY+ GR C+ +C
Sbjct: 2403 CLDMDECSQVPKPCTF-------LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQH 2455
Query: 700 -----------------PPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPH 742
PP +H F+ A G+ + P R C+ H
Sbjct: 2456 NCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFR-CECH 2514
Query: 743 GVW---SEPPQCLEIDECRS-QPCLHGGSCQDRVAGYLCLCSTGY----EGAHCELERDE 794
+ S C +++EC C HG CQ+++ GY C C G+ + A C E +
Sbjct: 2515 QGFTLVSSGHGCEDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENEC 2572
Query: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGF-----VGVHCETEVDACDS--SPCQHGGRCESG 847
+ P SCRN G + C CP+GF +G C+ EVD C PC + C +
Sbjct: 2573 ALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG-GCQ-EVDECAGRRGPCSYS--CANT 2628
Query: 848 GGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNG 887
G +LC CP+ +F G+G+C++ G
Sbjct: 2629 PGGFLCGCPQGYFR---------------AGQGHCVSGLG 2653
Score = 160 bits (404), Expect = 1e-38
Identities = 198/712 (27%), Positives = 270/712 (37%), Gaps = 138/712 (19%)
Query: 266 GHTTSVC---LALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLD--VNECASQPC 320
G+T +VC + R C NGG+CI P+ C+C+ GF G +C D C Q
Sbjct: 140 GYTGTVCGQPICDRGCHNGGRCI------GPN-RCACVYGFMGPQCERDYRTGPCFGQVG 192
Query: 321 QNGGTCTHGINSFRCQ---CPAGFG---GPTCETAQSPCDTKECQHGGQCQVENGSAVCV 374
G C H + C C A G G CE P C+ G + G+
Sbjct: 193 PEG--CQHQLTGLVCTKALCCATVGRAWGLPCELC--PAQPHPCRRGFIPNIHTGA---- 244
Query: 375 CQAGYTGAACEMDVDDCSPDPCL-NGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDAC 433
CQ DVD+C P L GGSCV++VG++ C RC G H + D+
Sbjct: 245 CQ----------DVDECQAVPGLCQGGSCVNMVGSFHC---------RCPVG-HRLSDSS 284
Query: 434 LSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCP-- 491
+ + G C G C G R + C + GRC A CP
Sbjct: 285 AACEDYRAGACFSVLFG--GRCAGDLAGHYTRRQC-----CCDRGRCWAAGPVPELCPPR 337
Query: 492 -LGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNAS--HSLPS--PCD 546
F LC + +P + G+ G L + + S +PS P +
Sbjct: 338 GSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGN 397
Query: 547 S------------------DPCFNGGSCDAHDDSYTCECPRGF-HGKHCEKARPHLCSSG 587
S + C N G C SY CEC G+ E C+S
Sbjct: 398 SNIGTATLNQTIDICRHFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSS 456
Query: 588 PCRNGGTCKEAGGEYHCSC--PYRFTGRHCEIGKPDSC--ASGPCHNGGTCFHYIGKYKC 643
PC + G C G YHC C ++ T D C + G CH G C + G ++C
Sbjct: 457 PCHH-GDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHL-GRCVNTEGSFQC 514
Query: 644 DCPPGF----SGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYM----GRRCQAE 695
C GF G++C + + C S G C + D F C C+ G++ G C
Sbjct: 515 VCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDI 573
Query: 696 VDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEID 755
+C P + NG + C L+ + RVC V S +E
Sbjct: 574 DECQTP------GICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKG 627
Query: 756 EC---------RSQPCL------HGGSCQ----DRVAGYLCLCSTGYEGAHCELERDECR 796
C +S+ C G CQ A + LCS+G + +EC
Sbjct: 628 SCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECA 687
Query: 797 AHP--CRNGGSCRNLPGAYVCRC----PAGFVGVHCETEVDAC--DSSPCQHGGRCESGG 848
P C N G C NL G+Y C C AG G C T+VD C +S C +G C++
Sbjct: 688 LDPEVCAN-GVCENLRGSYRCVCNLGYEAGASGKDC-TDVDECALNSLLCDNGW-CQNSP 744
Query: 849 GAYLCVCPESFFGYH----CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVG 896
G+Y C CP F + C+ V D C SSPC G C GS++C C G
Sbjct: 745 GSYSCSCPPGFHFWQDTEICKDV-DECLSSPCVS-GVCRNLAGSYTCKCGPG 794
Score = 145 bits (367), Expect = 2e-34
Identities = 178/697 (25%), Positives = 252/697 (36%), Gaps = 151/697 (21%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHL---DVNECASQPCQNGGTCTHGINSFR 334
C NG C+ Y C C GF H DV+ECA G+C + FR
Sbjct: 1373 CDNG-----QCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFR 1427
Query: 335 CQCPAGF----GGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY----TGAAC-E 385
C C G+ GG C D C +G C GS +C C + +G C +
Sbjct: 1428 CICNGGYELDRGGGNCTDINECADPVNCING-VCINTPGSYLCSCPQDFELNPSGVGCVD 1486
Query: 386 MDVDDC---SPDPCLNGGSCVDLVG----NYTCLCA-----------------EPFKGLR 421
+C + D +G SC +G +C C+ ++ L
Sbjct: 1487 TRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTL- 1545
Query: 422 CETGDHPVP----------DACLSAP--CHNGGTCVDADQGYVCECPEGFMGLDCRERVP 469
C G+ P D C P C GG CV+ + CECP G+ +
Sbjct: 1546 CPGGEGFQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGYHLSEHTRICE 1604
Query: 470 DDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGS--- 526
D EC G T C LG + +C E + N C H
Sbjct: 1605 DIDECSTHSGICGPGT--CYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQ 1662
Query: 527 ---------YLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTC--ECPRGFHGKH 575
+C C +N + PC++ P + + D C + P H
Sbjct: 1663 NELAFNVTRKMCCC--SYNIGQAWNRPCEACP-----TPISPDYQILCGNQAPGFLTDIH 1715
Query: 576 CEKAR--------PHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRH----CEIGKPDSC 623
K P +C++G C N G + C CP F CE D C
Sbjct: 1716 TGKPLDIDECGEIPAICANGICIN------QIGSFRCECPAGFNYNSILLACE--DVDEC 1767
Query: 624 AS--GPCHNGGTCFHYIGKYKCDCPPGFS---GRHCEIAPSPCFRSPCV-NGGTCEDRDT 677
S PC C + G Y+C C G+ G C + + C P V + G C D +
Sbjct: 1768 GSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEG 1826
Query: 678 DFFCHCQAGYMGRRCQAEVD---CGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPS 734
+ C C G+ QA D C +E NGT + Y C
Sbjct: 1827 SYMCLCHRGF-----QASADQTLCMDIDECDRQPCG-NGTCKNIIGSYNC---------- 1870
Query: 735 RIRVCQPHGVWSEPPQCLEIDECRS---QPCLHGGSCQDRVAGYLCLCSTGYE----GAH 787
+C P V + C++ DEC + Q C G C + + CLC G+E G +
Sbjct: 1871 ---LCFPGFVVTHNGDCVDFDECTTLVGQVC-RFGHCLNTAGSFHCLCQDGFELTADGKN 1926
Query: 788 CELERDEC--RAHPCRNGGSCRNLPGAYVCRCPAGF--VGVHCETEVDACDSSP--CQHG 841
C ++ +EC A C G+C+NL G++ C CP GF HC ++D C P C
Sbjct: 1927 C-VDTNECLSLAGTCL-PGTCQNLEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLF- 1982
Query: 842 GRCESGGGAYLCVCPESFF----GYHC-ETVSDPCFS 873
G C + G++ C+CP F G+ C +T CF+
Sbjct: 1983 GTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFT 2019
Score = 136 bits (342), Expect = 2e-31
Identities = 146/509 (28%), Positives = 195/509 (38%), Gaps = 114/509 (22%)
Query: 435 SAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGF 494
S C NGGTC +G C C +G+ G C + + D C NGGRC+G N C C GF
Sbjct: 121 SVSCMNGGTC----RGASCLCQKGYTGTVCGQPICDR-GCHNGGRCIGPNR--CACVYGF 173
Query: 495 FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC---VCHTDHNASHSLP---SPCDSD 548
G CE + PC P+G C +C +C + LP P
Sbjct: 174 MGPQCERDYRTGPC-FGQVGPEG--CQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPH 230
Query: 549 PCFNG-------GSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE 601
PC G G+C D EC +A P LC GG+C G
Sbjct: 231 PCRRGFIPNIHTGACQDVD-----EC----------QAVPGLC------QGGSCVNMVGS 269
Query: 602 YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKC--DCPPGFSGRHCEIAPS 659
+HC CP G DS A+ + G CF + +C D ++ R C
Sbjct: 270 FHCRCP---VGHRLS----DSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQC----- 317
Query: 660 PCFRSPCVNGG----TCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTR 715
C R C G C R ++ F + C + P G
Sbjct: 318 CCDRGRCWAAGPVPELCPPRGSNEF--------QQLCAQRLPLLPGHP---------GLF 360
Query: 716 LGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCL--------------EIDECR--S 759
G + + G L P+R+ PHG + L ID CR +
Sbjct: 361 PGLLGFGSNGMGPPL-GPARL---NPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFT 416
Query: 760 QPCLHGGSCQDRVAGYLCLCSTGYE---GAHCELERDECRAHPCRNGGSCRNLPGAYVCR 816
CL+ G C + Y C C+ GY C ++ DEC + PC + G C N+PG Y CR
Sbjct: 417 NLCLN-GRCLPTPSSYRCECNVGYTQDVRGEC-IDVDECTSSPCHH-GDCVNIPGTYHCR 473
Query: 817 CPAGFVGVHCE---TEVDAC-DSSPCQHGGRCESGGGAYLCVCPESF----FGYHCETVS 868
C GF +VD C S H GRC + G++ CVC F G +C +
Sbjct: 474 CYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHN 533
Query: 869 DPCFSSPCGGRGYCLASNGSHSCTCKVGY 897
+ C +S G CL +GS SC CK G+
Sbjct: 534 E-CATSTMCVNGVCLNEDGSFSCLCKPGF 561
Score = 114 bits (284), Expect = 9e-25
Identities = 147/604 (24%), Positives = 214/604 (35%), Gaps = 121/604 (20%)
Query: 350 QSPCDTKECQHG---GQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLV 406
+S C C+ G C N +C C G +C + C+NGG+C
Sbjct: 78 RSQCVVPICRRACGEGFCSQPN---LCTCADGTLAPSCGVSRGSGCSVSCMNGGTC---- 130
Query: 407 GNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRE 466
+CLC + + G C P+ D CHNGG C+ ++ C C GFMG C
Sbjct: 131 RGASCLCQKGYTGTVC---GQPICD----RGCHNGGRCIGPNR---CACVYGFMGPQCER 180
Query: 467 RV----------PDDCECRNGGRCLGANTTLCQCPLG-FFGLLCEFEITAMPCNMNTQCP 515
P+ C+ + G L LC +G +GL CE CP
Sbjct: 181 DYRTGPCFGQVGPEGCQHQLTG--LVCTKALCCATVGRAWGLPCEL------------CP 226
Query: 516 DGGYCMEHGGSYLCVCHT----DHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGF 571
+ G ++ HT D + ++P C GGSC S+ C CP G
Sbjct: 227 AQPHPCRRG--FIPNIHTGACQDVDECQAVPGLC------QGGSCVNMVGSFHCRCPVGH 278
Query: 572 H----GKHCEKARPHLCSSGPCRNGGTCK-EAGGEYHCSCPYRFTGRHCEIGKPDSCASG 626
CE R C S GG C + G Y T R C + A+G
Sbjct: 279 RLSDSSAACEDYRAGACFS--VLFGGRCAGDLAGHY--------TRRQCCCDRGRCWAAG 328
Query: 627 PC-----HNGGTCFHYIGKYKCDCPPGFSGRHCEI------APSPCFRSPCVNGGTCEDR 675
P G F + + PG G + P +N + R
Sbjct: 329 PVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDAR 388
Query: 676 DTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHAT-LRFNGTRLGAVALYACDRGYSLSAPS 734
+ +D +H T L NG L + Y C+ +
Sbjct: 389 GIPSLGPGNSNIGTATLNQTIDI-----CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDV 443
Query: 735 RIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE---LE 791
R +C+++DEC S PC H G C + Y C C G++ ++
Sbjct: 444 R-------------GECIDVDECTSSPC-HHGDCVNIPGTYHCRCYPGFQATPTRQACVD 489
Query: 792 RDEC-RAHPCRNGGSCRNLPGAYVCRCPAGFV----GVHCETEVDACDSSPCQHGGRCES 846
DEC + + G C N G++ C C AGF G +C + S+ C + G C +
Sbjct: 490 VDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVN-GVCLN 548
Query: 847 GGGAYLCVCPESFF----GYHCETVSDPCFSSPCGGRGYCLASNGSHSCTC----KVGYT 898
G++ C+C F G++C + D C + G+C + GS C C VG
Sbjct: 549 EDGSFSCLCKPGFLLAPGGHYCMDI-DECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTD 607
Query: 899 GEDC 902
G C
Sbjct: 608 GRVC 611
Score = 79.7 bits (195), Expect = 2e-14
Identities = 88/310 (28%), Positives = 111/310 (35%), Gaps = 86/310 (27%)
Query: 556 CDAHDDSYTCECPRGFHGKH------CEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYR 609
C + +Y C R F G+ C +A C G C C A G SC
Sbjct: 60 CGSRFHAYCCPGWRTFPGRSQCVVPICRRA----CGEGFCSQPNLCTCADGTLAPSCGVS 115
Query: 610 FTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNG 669
G C + C NGGTC C C G++G C P C NG
Sbjct: 116 -RGSGCSVS---------CMNGGTC----RGASCLCQKGYTGTVCG---QPICDRGCHNG 158
Query: 670 GTCEDRDTDFFCHCQAGYMGRRCQAEVDCGP------PEEVKHATLRFNGTRLGAVALYA 723
G C + C C G+MG +C+ + GP PE +H T+ AL
Sbjct: 159 GRCIGPNR---CACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTK----ALCC 211
Query: 724 CDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQ--PCLHGGSCQDRVAGYLCLCST 781
G + P + QPH CR P +H G+CQD
Sbjct: 212 ATVGRAWGLPCELCPAQPH-------------PCRRGFIPNIHTGACQDV---------- 248
Query: 782 GYEGAHCELERDECRAHP--CRNGGSCRNLPGAYVCRCPAGF----VGVHCET-EVDACD 834
DEC+A P C+ GGSC N+ G++ CRCP G CE AC
Sbjct: 249 -----------DECQAVPGLCQ-GGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 296
Query: 835 SSPCQHGGRC 844
S GGRC
Sbjct: 297 S--VLFGGRC 304
Score = 34.7 bits (78), Expect = 0.67
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 13/62 (20%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
C+ +PC +G CV + C C PGF+ AC+ V C + GG+
Sbjct: 453 CTSSPCHHGD-CVNIPGTYHCRCYPGFQATPTRQACVDVDE-C-----------IVSGGL 499
Query: 1371 CH 1372
CH
Sbjct: 500 CH 501
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 197 bits (500), Expect = 8e-50
Identities = 148/526 (28%), Positives = 209/526 (39%), Gaps = 103/526 (19%)
Query: 391 CSPDPCLNGGSCVDL-VGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQ 449
C P L G CV+ +G Y L E F C G + + L
Sbjct: 988 CRPGSVLRGRMCVNCPLGTYYNL--EHFTCESCRIGSYQDEEGQLECKL----------- 1034
Query: 450 GYVCECPEGFMGLDCRERVPDDC--ECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMP 507
CP G R DC +C+ G T CPLG + + + +
Sbjct: 1035 -----CPSGMYTEYIHSRNISDCKAQCKQGTYSYSGLETCESCPLGTY----QPKFGSRS 1085
Query: 508 CNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCEC 567
C CP+ ++ G + C PC G H C
Sbjct: 1086 C---LSCPENTSTVKRGAVNISACGV----------PCPEGKFSRSGLMPCHP------C 1126
Query: 568 PRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPY---RFTGRHCEIGKPDSCA 624
PR ++ + KA C + C GT AG C F+ + P S
Sbjct: 1127 PRDYYQPNAGKA---FCLA--CPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPAS-- 1179
Query: 625 SGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPS---PCFRSPCVNGGTCEDRDTDFFC 681
+G K RH EI+ CF +PC N GTC+ + C
Sbjct: 1180 -------------LGHIK--------KRH-EISSQVFHECFFNPCHNSGTCQQLGRGYVC 1217
Query: 682 HCQAGYMGRRCQAEVD-CGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQ 740
C GY G +C+ ++D C P + NG V + C+ C
Sbjct: 1218 LCPLGYTGLKCETDIDECSPLPCLN------NGVCKDLVGEFICE-------------C- 1257
Query: 741 PHGVWSEPPQCLE-IDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP 799
P G + +C E I+EC S PCL+ G C D VAGY C C G+ G HCE E +EC+++P
Sbjct: 1258 PSGYTGQ--RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP 1315
Query: 800 CRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESF 859
C N C + G ++C+CP GF+G C VD C S PC++G C+ G ++ C+C F
Sbjct: 1316 CLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGF 1375
Query: 860 FGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKE 905
G HCE + C S+PC + C+ S+SC C+ G++G+ C E
Sbjct: 1376 TGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 178 bits (451), Expect = 4e-44
Identities = 89/223 (39%), Positives = 113/223 (50%), Gaps = 12/223 (5%)
Query: 313 NECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAV 372
+EC PC N GTC + C CP G+ G CET C C + G C+ G +
Sbjct: 1195 HECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1254
Query: 373 CVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDA 432
C C +GYTG CE ++++CS PCLN G CVD V Y C C + F GL CET +
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET----EVNE 1310
Query: 433 CLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCL-GANTTLC 488
C S PC N C D G++C+CP GF+G C + V D+C C+NG C GAN+ C
Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNV-DECLSQPCKNGATCKDGANSFRC 1369
Query: 489 QCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC 531
C GF G CE I N C + C++ SY C C
Sbjct: 1370 LCAAGFTGSHCELNINECQSN---PCRNQATCVDELNSYSCKC 1409
Score = 173 bits (439), Expect = 9e-43
Identities = 85/230 (36%), Positives = 111/230 (48%), Gaps = 13/230 (5%)
Query: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
PC N G C Y C C G+TG +C D++EC+ PC N G C + F C+
Sbjct: 1201 PCHNSGTCQQL----GRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICE 1256
Query: 337 CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPC 396
CP+G+ G CE + C + C + G C C C G+ G CE +V++C +PC
Sbjct: 1257 CPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPC 1316
Query: 397 LNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECP 456
LN C D VG + C C F G RC D CLS PC NG TC D + C C
Sbjct: 1317 LNNAVCEDQVGGFLCKCPPGFLGTRCGKN----VDECLSQPCKNGATCKDGANSFRCLCA 1372
Query: 457 EGFMGLDCRERVPDDCE---CRNGGRCLG-ANTTLCQCPLGFFGLLCEFE 502
GF G C + ++C+ CRN C+ N+ C+C GF G CE E
Sbjct: 1373 AGFTGSHCELNI-NECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 152 bits (383), Expect = 3e-36
Identities = 63/151 (41%), Positives = 81/151 (53%)
Query: 756 ECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVC 815
EC PC + G+CQ GY+CLC GY G CE + DEC PC N G C++L G ++C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Query: 816 RCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSP 875
CP+G+ G CE ++ C SSPC + G C G Y C C + F G HCET + C S+P
Sbjct: 1256 ECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP 1315
Query: 876 CGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
C C G C C G+ G C K +
Sbjct: 1316 CLNNAVCEDQVGGFLCKCPPGFLGTRCGKNV 1346
Score = 103 bits (257), Expect = 1e-21
Identities = 155/626 (24%), Positives = 223/626 (35%), Gaps = 133/626 (21%)
Query: 328 HGINSFRCQCPAGFGGPTCETAQSPCDTKECQHG--GQCQVENGSAVCV-CQAGY----- 379
HG +S RC + G + C T ++G + G A + C G+
Sbjct: 2982 HGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGL 3041
Query: 380 TGAACEMDVDDCSPDPCLNGGSCVDL-----------------VGNYTCLCAEPFKG--- 419
+ CE D S P SC L V Y+C +G
Sbjct: 3042 SEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSD 3101
Query: 420 LRC-ETG----DHPV--PDACLSAPCHNGGTCVDADQGYVCE----CPEGFMGLDCRERV 468
L C E G +PV P +C S P Y E C EG+ +
Sbjct: 3102 LICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYT----MDTD 3157
Query: 469 PDDCECRNGGRC----LGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHG 524
D C+ GR + + C P +L + ++ ++ C +G Y E
Sbjct: 3158 TDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEG-YTFE-- 3214
Query: 525 GSYLCVCHTDHN----------ASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGK 574
G + VC D + S P + F GS + + +C G+
Sbjct: 3215 GVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYE-- 3272
Query: 575 HCEKARPHLCSSGPCRNGGT--CKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGP----- 627
E R +C +GG CKE C P F +I ++ +GP
Sbjct: 3273 -LEGNRERVCQENRQWSGGVAICKET----RCETPLEFLNGKADI---ENRTTGPNVVYS 3324
Query: 628 CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSP-CFRSPCV-------NGGTCEDR---D 676
C+ G + G + C + H P P C +PC N E D
Sbjct: 3325 CNRG---YSLEGPSEAHCTENGTWSH----PVPLCKPNPCPVPFVIPENALLSEKEFYVD 3377
Query: 677 TDFFCHCQAGYM------------------GRRCQAEVDCGPPEEVKHATLRFNGTRLGA 718
+ C+ G++ +C+ ++ CGPP V++A R + G
Sbjct: 3378 QNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCE-KISCGPPAHVENAIARGVHYQYGD 3436
Query: 719 VALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCL 778
+ Y+C GY L R VC +G W+ PP C + CR PC +GG CQ A C
Sbjct: 3437 MITYSCYSGYMLEGFLR-SVCLENGTWTSPPICRAV--CRF-PCQNGGICQRPNA---CS 3489
Query: 779 CSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPC 838
C G+ G CE + PC NGG C Y C CP G+ G C T V C SPC
Sbjct: 3490 CPEGWMGRLCE---EPICILPCLNGGRC---VAPYQCDCPPGWTGSRCHTAV--C-QSPC 3540
Query: 839 QHGGRCESGGGAYLCVCPESFFGYHC 864
+GG+C C C S+ G++C
Sbjct: 3541 LNGGKCVRPN---RCHCLSSWTGHNC 3563
Score = 92.8 bits (229), Expect = 2e-18
Identities = 41/87 (47%), Positives = 51/87 (58%), Gaps = 5/87 (5%)
Query: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
CG CL+ +PC NG C D G S+ C C +GFTG C L++NEC S PC+N
Sbjct: 1342 CGKNVDECLS-QPCKNGATCKD----GANSFRCLCAAGFTGSHCELNINECQSNPCRNQA 1396
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQS 351
TC +NS+ C+C GF G CET QS
Sbjct: 1397 TCVDELNSYSCKCQPGFSGKRCETEQS 1423
Score = 91.3 bits (225), Expect = 6e-18
Identities = 119/463 (25%), Positives = 167/463 (36%), Gaps = 86/463 (18%)
Query: 266 GHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLD---VNECASQPCQN 322
G+T C G+ + ++ +P C T H D VN S C
Sbjct: 3151 GYTMDTDTDTFTCQKDGRWFPERISCSPK-KCPLPENITHILVHGDDFSVNRQVSVSCAE 3209
Query: 323 GGTCTHGINSFRCQCPAGFGGPTCETAQSP--CDTKEC-QHG---GQCQVENGSAVCVCQ 376
G T G+N CQ + P + + SP C E +HG G + + C+
Sbjct: 3210 GYTF-EGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCE 3268
Query: 377 AGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSA 436
GY V C + +GG +C E RCET P+ A
Sbjct: 3269 PGYELEGNRERV--CQENRQWSGG---------VAICKET----RCET---PLEFLNGKA 3310
Query: 437 PCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQ---CPLG 493
N T V C G+ P + C G LC+ CP+
Sbjct: 3311 DIENRTT----GPNVVYSCNRGYS-----LEGPSEAHCTENGTW-SHPVPLCKPNPCPVP 3360
Query: 494 FF----GLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASH--------SL 541
F LL E E + N++ +C +G HG + C+ D + S
Sbjct: 3361 FVIPENALLSEKEFY-VDQNVSIKCREGFLLQGHG---IITCNPDETWTQTSAKCEKISC 3416
Query: 542 PSPCDSDPCFNGGSCDAHDDSYTCECP-----RGFHGKHCEK----ARPHLCSSG---PC 589
P + G + D T C GF C + P +C + PC
Sbjct: 3417 GPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPC 3476
Query: 590 RNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGF 649
+NGG C+ CSCP + GR CE + PC NGG C + Y+CDCPPG+
Sbjct: 3477 QNGGICQRPNA---CSCPEGWMGRLCE----EPICILPCLNGGRC---VAPYQCDCPPGW 3526
Query: 650 SGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRC 692
+G C A +SPC+NGG C + CHC + + G C
Sbjct: 3527 TGSRCHTA---VCQSPCLNGGKCVRPNR---CHCLSSWTGHNC 3563
Score = 62.8 bits (151), Expect = 2e-09
Identities = 73/272 (26%), Positives = 97/272 (35%), Gaps = 38/272 (13%)
Query: 513 QCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAH------DDSYTCE 566
QC +G Y + G C + + + PS D D C G C H D SY C
Sbjct: 1715 QCNNGYYLL---GDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICS 1771
Query: 567 C--PRGFHGKHCEKARPHLCSS-GPCRNGGTCKE---AGGEYHCSCP--YRFTGRHCEIG 618
C P GK+C A P C + G NG + E G E SC Y+ G
Sbjct: 1772 CVPPYTGDGKNC--AEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMG------ 1823
Query: 619 KPDSCASGPCHNGGTCFHYIGKYKC-DC-PPGFSGRHCEIAPSPCFRSP----CVNGGTC 672
C G H I K C P C + F S C G T
Sbjct: 1824 ----VTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTL 1879
Query: 673 E-DRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLS 731
D+++ + + C+ V C PE + + +G + A Y+CD GYSL
Sbjct: 1880 AGDKESSCLANSSWSHSPPVCEP-VKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQ 1938
Query: 732 APSRIRVCQPHGVWSEPPQCLEIDECRSQPCL 763
PS I C G+W P + C P +
Sbjct: 1939 GPSIIE-CTASGIWDRAPPACHLVFCGEPPAI 1969
Score = 58.9 bits (141), Expect = 3e-08
Identities = 32/84 (38%), Positives = 40/84 (47%), Gaps = 13/84 (15%)
Query: 263 GGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQN 322
G G + + PCLNGG+C+ Y C C G+TG RCH V C S PC N
Sbjct: 3493 GWMGRLCEEPICILPCLNGGRCV-------APYQCDCPPGWTGSRCHTAV--CQS-PCLN 3542
Query: 323 GGTCTHGINSFRCQCPAGFGGPTC 346
GG C + RC C + + G C
Sbjct: 3543 GGKC---VRPNRCHCLSSWTGHNC 3563
Score = 54.3 bits (129), Expect = 8e-07
Identities = 43/157 (27%), Positives = 66/157 (42%), Gaps = 27/157 (17%)
Query: 645 CPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEV 704
C PGF ++ +P C+N G T HC+ + CG P +
Sbjct: 1658 CDPGF-----QLVGNPV--QYCLNQGQW----TQPLPHCE----------RISCGVPPPL 1696
Query: 705 KHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWS-EPPQCLEIDECR-SQPC 762
++ + G+ Y C+ GY L SR+ C +G W+ P CL++DEC C
Sbjct: 1697 ENGFHSADDFYAGSTVTYQCNNGYYLLGDSRM-FCTDNGSWNGVSPSCLDVDECAVGSDC 1755
Query: 763 LHGGSCQDRVAGYLCLCSTGY--EGAHCELERDECRA 797
SC + Y+C C Y +G +C E +C+A
Sbjct: 1756 SEHASCLNVDGSYICSCVPPYTGDGKNC-AEPIKCKA 1791
Score = 50.4 bits (119), Expect = 1e-05
Identities = 18/33 (54%), Positives = 23/33 (69%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C NPC+N TCV +++SC C PGF G+RCE
Sbjct: 1387 CQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 47.8 bits (112), Expect = 8e-05
Identities = 25/66 (37%), Positives = 32/66 (48%), Gaps = 9/66 (13%)
Query: 837 PCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVG 896
PCQ+GG C+ C CPE + G CE +P PC G C+A + C C G
Sbjct: 3475 PCQNGGICQRPNA---CSCPEGWMGRLCE---EPICILPCLNGGRCVA---PYQCDCPPG 3525
Query: 897 YTGEDC 902
+TG C
Sbjct: 3526 WTGSRC 3531
Score = 45.4 bits (106), Expect = 4e-04
Identities = 20/44 (45%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
C PC+NG TC GA++ C C GF G CEL + S PC
Sbjct: 1349 CLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPC 1392
Score = 45.1 bits (105), Expect = 5e-04
Identities = 58/245 (23%), Positives = 85/245 (34%), Gaps = 66/245 (26%)
Query: 545 CDS--DPCFNGGSCDA--HDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGG 600
CD D C GSC H + C C +G++GK G
Sbjct: 281 CDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGK------------------------GL 316
Query: 601 EYHCS-CPYRFTGRHCEIGKP---DSCASGPCHNGGTCFHYIGKYKCDCPPGF--SGRHC 654
+Y C+ CP +G + G P SC P N + C C G+ SG+ C
Sbjct: 317 QYECTACP---SGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTC 373
Query: 655 EIAPSPCFRSPCVNGGTCEDRDTDFF-------CHCQAGYMGRR---------------- 691
E+ P + P NG ++ + F CH +G
Sbjct: 374 ELVHCPALKPP-ENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESY 432
Query: 692 CQAEVDCGPPEEVKHATLRFNGTRL--GAVALYACDRGYSLSAPSRIRVCQPHGVWSEP- 748
C+ C + KH + + + L ACD GY L ++ CQ + W P
Sbjct: 433 CRVRT-CPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKL-TCQGNSQWDGPE 490
Query: 749 PQCLE 753
P+C+E
Sbjct: 491 PRCVE 495
Score = 44.3 bits (103), Expect = 8e-04
Identities = 52/200 (26%), Positives = 68/200 (34%), Gaps = 36/200 (18%)
Query: 643 CDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFF----CHCQAGYMGR-----RCQ 693
C +SG + P C P + G E D F HC GY+ CQ
Sbjct: 2873 CLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQ 2932
Query: 694 AE------------VDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQP 741
++ V+CGPPE++ H G Y C GY L S R C
Sbjct: 2933 SDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSS-RRCLS 2991
Query: 742 HGVWS-EPPQCLEIDECR-SQPCLHGGSCQD---------RVAGYLCLCSTGYEGAHCEL 790
+G WS P CL CR S P + G+ R+ + G CE
Sbjct: 2992 NGSWSGSSPSCL---PCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEA 3048
Query: 791 ERDECRAHPCRNGGSCRNLP 810
+ P SC +LP
Sbjct: 3049 DGQWSSGFPHCEHTSCGSLP 3068
Score = 42.7 bits (99), Expect = 0.002
Identities = 78/373 (20%), Positives = 120/373 (32%), Gaps = 74/373 (19%)
Query: 429 VPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLC 488
V + + + C +C++ D Y+C C + G +G C A C
Sbjct: 1746 VDECAVGSDCSEHASCLNVDGSYICSCVPPYTG--------------DGKNC--AEPIKC 1789
Query: 489 QCPLGFFGLLCEFEITAMPCNMNTQCPDGGY--------CMEHG--GSYLCVCHTDHNAS 538
+ P EI + + C +G C+E G + C
Sbjct: 1790 KAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGK 1849
Query: 539 HSLP-SPCDSDPCFNGGSCDAH--DDSYTC------ECPRGFHGKHCEKA-RPHLCSSGP 588
++P + C + F GS + + YT C H P CSS
Sbjct: 1850 PAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPE 1909
Query: 589 CRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCD-CPP 647
N G +G Y + Y SC +G G + D PP
Sbjct: 1910 NINNGKYILSGLTYLSTASY-------------SCDTGYSLQGPSIIECTASGIWDRAPP 1956
Query: 648 GFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYM------------------G 689
C P + + G R+T + C+ GY
Sbjct: 1957 ACHLVFC--GEPPAIKDAVITGNNFTFRNTVTYT-CKEGYTLAGLDTIECLADGKWSRSD 2013
Query: 690 RRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPP 749
++C A V C P V HA+ G +A Y C GYSL+ S++ +C G W PP
Sbjct: 2014 QQCLA-VSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQL-LCNAQGKW-VPP 2070
Query: 750 QCLEIDECRSQPC 762
+ ++ C + C
Sbjct: 2071 EGQDMPRCIAHFC 2083
Score = 42.0 bits (97), Expect = 0.004
Identities = 52/197 (26%), Positives = 70/197 (35%), Gaps = 35/197 (17%)
Query: 615 CEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGR----HCEIAPSPCFRSPCVNGG 670
C+ GK G C C + G ++C C G+ G+ C PS ++ GG
Sbjct: 281 CDEGKDCCDRMGSCK----CGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGG 336
Query: 671 T-----CEDRD--------TDFFCHCQAGYM--GRRCQAEVDCG---PPEEVKHATLRFN 712
C D + + C C+ GY G+ C+ V C PPE N
Sbjct: 337 ISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCEL-VHCPALKPPENGYFIQNTCN 395
Query: 713 GTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDEC--RSQPCLHGGSCQD 770
A C G+ L S I +C P+G+WS + C QP SC
Sbjct: 396 N-HFNAACGVRCHPGFDLVGSSII-LCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCST 453
Query: 771 RVAGY----LCLCSTGY 783
R Y L C GY
Sbjct: 454 REMLYKTTCLVACDEGY 470
Score = 42.0 bits (97), Expect = 0.004
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
CS +PC N G CV G + C C GF G CE + S PC
Sbjct: 1273 CSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPC 1316
Score = 40.8 bits (94), Expect = 0.009
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 5/92 (5%)
Query: 696 VDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWS-EPPQCLEI 754
++C P ++ LRF T +G+ Y+C G+ L A S +R+C + WS P+C I
Sbjct: 2715 IECDLPTAPENGFLRFTETSMGSAVQYSCKPGHIL-AGSDLRLCLENRKWSGASPRCEAI 2773
Query: 755 DECRSQPCLHG---GSCQDRVAGYLCLCSTGY 783
+ P ++G GS ++ C GY
Sbjct: 2774 SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGY 2805
Score = 40.4 bits (93), Expect = 0.012
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 4/77 (5%)
Query: 691 RCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSE-PP 749
RC+A + C P V + +++ + + Y CD GY L+ R R CQ W E P
Sbjct: 2769 RCEA-ISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTER-RTCQDDKNWDEDEP 2826
Query: 750 QCLEIDECRSQPCLHGG 766
C+ +D C S P G
Sbjct: 2827 ICIPVD-CSSPPVSANG 2842
Score = 40.0 bits (92), Expect = 0.016
Identities = 53/230 (23%), Positives = 87/230 (37%), Gaps = 49/230 (21%)
Query: 541 LPSPCDSDPCFNGGSCDAHDDSYTC----ECPRGFHGKHCEKARPHLCSSGPCRNGGTCK 596
+P C P G + S+ C +GF+ K +K+ TC
Sbjct: 2142 IPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKS--------------TC- 2186
Query: 597 EAGGEYHCSCPYRFTGRHCEIGKPDSCASGPC-HNGGTCFHYIGKYKCDCPPGFSGRHCE 655
EA G++ P T G+P +G H G F +Y+C+ PG+
Sbjct: 2187 EATGQWSSPIP---TCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCN--PGYKS---- 2237
Query: 656 IAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTR 715
SP F C+ + H ++ M C +DCG P +++ ++
Sbjct: 2238 -VGSPVF--------VCQ---ANRHWHSESPLM---C-VPLDCGKPPPIQNGFMKGENFE 2281
Query: 716 LGAVALYACDRGYSLSAPSRIRVCQPHGVWSEP--PQCLEIDECRSQPCL 763
+G+ + C+ GY L S CQ G W++ P+C+ +C P L
Sbjct: 2282 VGSKVQFFCNEGYELVGDSS-WTCQKSGKWNKKSNPKCMPA-KCPEPPLL 2329
Score = 40.0 bits (92), Expect = 0.016
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 676 DTDFFCHCQAGYMGRR--CQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAP 733
+T C ++G + C+A ++C P+E+ + + G Y+C+RG+ L P
Sbjct: 2475 NTTTLCGENGHWLGGKPTCKA-IECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGP 2533
Query: 734 SRIRVCQPHGVWS-EPPQCLEIDECRSQPCLHG 765
S + C G W + P C I QP +G
Sbjct: 2534 SAL-TCLETGDWDVDAPSCNAIHCDSPQPIENG 2565
Score = 38.9 bits (89), Expect = 0.035
Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 10/63 (15%)
Query: 1315 PCQNGGTCVPGADAHSCDCGPGFKGRRCE-----LACIKVSRPCTRLFSETKAFPVWEGG 1369
PCQNGG C ++C C G+ GR CE L C+ R C + + P W G
Sbjct: 3475 PCQNGGIC---QRPNACSCPEGWMGRLCEEPICILPCLNGGR-CVAPY-QCDCPPGWTGS 3529
Query: 1370 VCH 1372
CH
Sbjct: 3530 RCH 3532
Score = 38.5 bits (88), Expect = 0.046
Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 5/39 (12%)
Query: 1315 PCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
PC NGG CV + CDC PG+ G RC A + PC
Sbjct: 3507 PCLNGGRCVA---PYQCDCPPGWTGSRCHTAVCQ--SPC 3540
Score = 38.1 bits (87), Expect = 0.060
Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 1/44 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
C NPC N C C C PGF G RC + +S+PC
Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPC 1354
Score = 37.4 bits (85), Expect = 0.10
Identities = 38/130 (29%), Positives = 47/130 (36%), Gaps = 26/130 (20%)
Query: 787 HCELERDECRAHPCRNGGSCR--NLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRC 844
HC DE + C GSC+ G + C C G+ G + E AC S + G
Sbjct: 276 HCSYLCDEGK-DCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEG-- 332
Query: 845 ESGGGAYLCV-CPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCA 903
S GG C+ CP D +SP G S C C+ GY
Sbjct: 333 -SPGGISSCIPCP------------DENHTSPPG-------STSPEDCVCREGYRASGQT 372
Query: 904 KELFPPTALK 913
EL ALK
Sbjct: 373 CELVHCPALK 382
Score = 37.4 bits (85), Expect = 0.10
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 8/93 (8%)
Query: 698 CGPPEEVKHAT-LRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEP-PQCLEID 755
C PP + + + G+ Y+C G+ L S +CQP G WS P P+C+ +
Sbjct: 2381 CTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTT-LCQPDGTWSSPLPECVPV- 2438
Query: 756 ECRSQPCLHGGSCQDRVAGYLC----LCSTGYE 784
EC + G + YL C G+E
Sbjct: 2439 ECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFE 2471
Score = 36.6 bits (83), Expect = 0.18
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
CS PC N G C C+C G+ G+RCE
Sbjct: 1235 CSPLPCLNNGVCKDLVGEFICECPSGYTGQRCE 1267
Score = 36.6 bits (83), Expect = 0.18
Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 692 CQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC 751
C A + C P+ +++ + GA+ +Y+C G+ + A ++ C+ G S P C
Sbjct: 2551 CNA-IHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQV-AGHAMQTCEESGWSSSIPTC 2608
Query: 752 LEIDECRSQPCLHGGSC 768
+ ID C P + G C
Sbjct: 2609 MPID-CGLPPHIDFGDC 2624
Score = 35.8 bits (81), Expect = 0.30
Identities = 19/61 (31%), Positives = 22/61 (36%), Gaps = 11/61 (18%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
C NPC N GTC + C C G+ G +CE E P GV
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETD-----------IDECSPLPCLNNGV 1245
Query: 1371 C 1371
C
Sbjct: 1246 C 1246
Score = 35.0 bits (79), Expect = 0.51
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
Query: 696 VDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVW-SEPPQCLEI 754
V+C PEE+ + + G + ALY C G+ L + +C +G W P C I
Sbjct: 2438 VECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFEL-VGNTTTLCGENGHWLGGKPTCKAI 2496
Query: 755 DECRSQPCLHG 765
+ + + L+G
Sbjct: 2497 ECLKPKEILNG 2507
Score = 34.7 bits (78), Expect = 0.67
Identities = 30/122 (24%), Positives = 44/122 (36%), Gaps = 18/122 (14%)
Query: 380 TGAACEMDVDDCS------PDPCLNGGSCV--DLVGNYTCLCAEPFKGLRCETGDHPVPD 431
+G+ + D+ CS D C GSC G++ C+C + + G + P
Sbjct: 266 SGSFIQDDMVHCSYLCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPS 325
Query: 432 ACLSAPCHNGG--TCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQ 489
GG +C+ CP+ P+DC CR G R G L
Sbjct: 326 GTYKPEGSPGGISSCIP--------CPDENHTSPPGSTSPEDCVCREGYRASGQTCELVH 377
Query: 490 CP 491
CP
Sbjct: 378 CP 379
Score = 32.3 bits (72), Expect = 3.3
Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 17/90 (18%)
Query: 864 CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGE--DCAKELFPPTALKMERVEESG 921
C V + S C CL +GS+ C+C YTG+ +CA+ + + + G
Sbjct: 1743 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPI---------KCKAPG 1793
Query: 922 VSISWNPPNGPAARQMLD-GYAVTYVSSDG 950
NP NG ++ ++ G VT+ +G
Sbjct: 1794 -----NPENGHSSGEIYTVGAEVTFSCQEG 1818
Score = 30.8 bits (68), Expect = 9.6
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 8/64 (12%)
Query: 272 CLALRPCLNGGKCID--DCVTGNPSYTCSCLSGFTGRRCHLDVNECASQ-PCQNGGTCTH 328
CL + C G C + C+ + SY CSC+ +TG D CA C+ G +
Sbjct: 1743 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG-----DGKNCAEPIKCKAPGNPEN 1797
Query: 329 GINS 332
G +S
Sbjct: 1798 GHSS 1801
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 196 bits (497), Expect = 2e-49
Identities = 189/719 (26%), Positives = 250/719 (34%), Gaps = 189/719 (26%)
Query: 284 CIDDCVTGN--PSYTCSCLSGFTGRRCHLDVNECA--------SQPCQNGGTCTHGINSF 333
C +CV G C C+ G+ G C +ECA +PC G + S
Sbjct: 105 CAQECVHGRCVAPNQCQCVPGWRGDDCS---SECAPGMWGPQCDKPCSCGNNSSCDPKSG 161
Query: 334 RCQCPAGFGGPTCETAQSP------CDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMD 387
C CP+G P C +P C + HG C + G+ C C A TG +C++
Sbjct: 162 VCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGA--CFCPAERTGPSCDVS 219
Query: 388 VDD------C-SPDPCLNGGSCVDLVGNYTCLCAEPFKG----LRCETGDHPVPDACLSA 436
C S C NGG G+ C C + G L C G H P+
Sbjct: 220 CSQGTSGFFCPSTHSCQNGGVFQTPQGS--CSCPPGWMGTICSLPCPEGFHG-PNCSQEC 276
Query: 437 PCHNGGTCVDADQGYVCECPEGFMGLDCRERVP---------DDCECRNGGRCLGANTTL 487
CHNGG C D G C C G+ G CRE P + C+C RC AN
Sbjct: 277 RCHNGGLC-DRFTGQ-CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGA- 333
Query: 488 CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNAS-HSLPSPCD 546
C C GF G C + CPDG Y + C C +H+ S H + C
Sbjct: 334 CLCEHGFTGDRCTDRL----------CPDGFYGLSCQAP--CTCDREHSLSCHPMNGECS 381
Query: 547 SDP-------------------------CFNGGSCDAHDDSYTCECPRGFHGKHCEKARP 581
P C +GG C A S C+C G+ G HC P
Sbjct: 382 CLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQA--TSGLCQCAPGYTGPHCASLCP 439
Query: 582 H-----LCSSG-PCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPD-----SC-ASGPCH 629
CS+ C N C GE C C + +C + P SC AS C
Sbjct: 440 PDTYGVNCSARCSCENAIACSPIDGE--CVCKEGWQRGNCSVPCPPGTWGFSCNASCQCA 497
Query: 630 NGGTCFHYIGKYKCDCPPGFSGRHCEI-APSPCFRSPCVNGGTCEDRD----TDFFCHCQ 684
+ C G C C PG+ G HC++ P F C + C+ D C CQ
Sbjct: 498 HEAVCSPQTGA--CTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQ 555
Query: 685 AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGV 744
AG+MG RC + C P G+
Sbjct: 556 AGWMGARCH--LSC------------------------------------------PEGL 571
Query: 745 WSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE----RDECRAHPC 800
W ++ + C +GG+C C+C+ G+ G C+ R R PC
Sbjct: 572 WG-------VNCSNTCTCKNGGTCLPENGN--CVCAPGFRGPSCQRSCQPGRYGKRCVPC 622
Query: 801 RNGGSCRNLPGAYVCRCPAGFVGVHCETEV-------DACDSSPCQHGGRCESGGGAYLC 853
+ P C C AG+ G C + + C HGG C G+ C
Sbjct: 623 KCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGS--C 680
Query: 854 VCPESFFGYHC----------ETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
+CP + G+HC S PC CG C G +C C G++G C
Sbjct: 681 ICPLGWTGHHCLEGCPLGTFGANCSQPC---QCGPGEKCHPETG--ACVCPPGHSGAPC 734
Score = 160 bits (404), Expect = 1e-38
Identities = 161/638 (25%), Positives = 222/638 (34%), Gaps = 147/638 (23%)
Query: 326 CTHG--INSFRCQCPAGFGGPTCETAQSP------CDTKECQHGGQCQVENGSAVCVCQA 377
C HG + +CQC G+ G C + +P CD K C G + S VC C +
Sbjct: 109 CVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCD-KPCSCGNNSSCDPKSGVCSCPS 167
Query: 378 GYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAP 437
G C + C+P G +C + C C G C+ P AC
Sbjct: 168 GLQPPNC---LQPCTPG--YYGPAC-----QFRCQC----HGAPCD----PQTGACFCPA 209
Query: 438 CHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGL 497
G +C C +G G C P C+NGG C CP G+ G
Sbjct: 210 ERTGPSCD-------VSCSQGTSGFFC----PSTHSCQNGG-VFQTPQGSCSCPPGWMGT 257
Query: 498 LCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCD 557
+C CP+G HG + C C NGG CD
Sbjct: 258 ICSLP-----------CPEGF----HGPNCSQECR-----------------CHNGGLCD 285
Query: 558 AHDDSYTCECPRGFHGKHCEKARP------HLCSSGPCRNGGTCKEAGGEYHCSCPYRFT 611
C C G+ G C + P + C C A G C C + FT
Sbjct: 286 RFTGQ--CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGA--CLCEHGFT 341
Query: 612 GRHCEIGK-PDSCASGPCHNGGTCF--HYIGKY----KCDCPPGFSGRHCEIAPSPCFRS 664
G C PD C TC H + + +C C PG++G HC +
Sbjct: 342 GDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHG 401
Query: 665 P-------CVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLG 717
P C++GG C+ T C C GY G C + PP+ +
Sbjct: 402 PGCQEHCLCLHGGVCQA--TSGLCQCAPGYTGPHCASLC---PPDTYG----------VN 446
Query: 718 AVALYACDRGYSLSAPSRIRVCQPHGVWSE-------PPQCLEIDECRSQPCLHGGSCQD 770
A +C+ + S VC+ W PP S C H C
Sbjct: 447 CSARCSCENAIACSPIDGECVCKEG--WQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSP 504
Query: 771 RVAGYLCLCSTGYEGAHCELE------RDECRAH-PCRNGGSCRNLPGAYVCRCPAGFVG 823
+ C C+ G+ GAHC+L + C + C + C + G C+C AG++G
Sbjct: 505 QTGA--CTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGR--CQCQAGWMG 560
Query: 824 VHCETE-------VDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDP------ 870
C V+ ++ C++GG C G CVC F G C+ P
Sbjct: 561 ARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGN--CVCAPGFRGPSCQRSCQPGRYGKR 618
Query: 871 CFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
C C +C SNG +C C G+TG DC++ P
Sbjct: 619 CVPCKCANHSFCHPSNG--TCYCLAGWTGPDCSQPCPP 654
Score = 147 bits (371), Expect = 7e-35
Identities = 158/569 (27%), Positives = 203/569 (35%), Gaps = 123/569 (21%)
Query: 265 CGHTTS--VCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQP--- 319
C TS C + C NGG V P +CSC G+ G C L E P
Sbjct: 220 CSQGTSGFFCPSTHSCQNGG------VFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCS 273
Query: 320 ----CQNGGTCTHGINSFRCQCPAGFGGPTCET-------AQSPCDTKECQHGGQCQVEN 368
C NGG C +C+C G+ G C Q +T +C +C N
Sbjct: 274 QECRCHNGGLCDRFTG--QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPAN 331
Query: 369 GSAVCVCQAGYTGAACEMDVDDCSPD---------PCL----NGGSCVDLVGNYTCLCAE 415
G+ C+C+ G+TG C D PD PC + SC + G C C
Sbjct: 332 GA--CLCEHGFTGDRC---TDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGE--CSCLP 384
Query: 416 PFKGLRCETG---DHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD- 471
+ GL C D P C +GG C A G +C+C G+ G C P D
Sbjct: 385 GWAGLHCNESCPQDTHGPGCQEHCLCLHGGVC-QATSG-LCQCAPGYTGPHCASLCPPDT 442
Query: 472 --------CECRNGGRCLGANTTLCQCPLGF----FGLLCEFEITAMPCNMNTQCPDGGY 519
C C N C + C C G+ + C CN + QC
Sbjct: 443 YGVNCSARCSCENAIACSPIDGE-CVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAV 501
Query: 520 CMEHGGSYLCVCHTDHNASH-SLPSPCDS--DPCFNGGSCDAHDDSYT-----CECPRGF 571
C G+ C C + +H LP P + C + CD H D C+C G+
Sbjct: 502 CSPQTGA--CTCTPGWHGAHCQLPCPKGQFGEGCASRCDCD-HSDGCDPVHGRCQCQAGW 558
Query: 572 HGKHCEKARPHLCSSGPCRNGGTCKEAG----GEYHCSCPYRFTG----RHCEIGK---- 619
G C + P C N TCK G +C C F G R C+ G+
Sbjct: 559 MGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKR 618
Query: 620 --PDSCASGP-CH-NGGTCFHYIGKYKCD----CPPGFSGRHCEIAPSPCFRSPCVNGGT 671
P CA+ CH + GTC+ G D CPPG G +C C C +GGT
Sbjct: 619 CVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENC---AQTC---QCHHGGT 672
Query: 672 CEDRDTDFFC-----------HCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA 720
C +D C C G G C CGP E+ T GA
Sbjct: 673 CHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPET--------GAC- 723
Query: 721 LYACDRGYSLSAPSRIRVCQPHGVWSEPP 749
C G+S AP RI + +P V P
Sbjct: 724 --VCPPGHS-GAPCRIGIQEPFTVMPTTP 749
Score = 92.4 bits (228), Expect = 3e-18
Identities = 110/405 (27%), Positives = 141/405 (34%), Gaps = 118/405 (29%)
Query: 542 PSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE 601
P+ C P + G C + EC G G C+K CS C N +C G
Sbjct: 117 PNQCQCVPGWRGDDCSS-------ECAPGMWGPQCDKP----CS---CGNNSSCDPKSGV 162
Query: 602 YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIG---KYKCDCPPGFSGRHCEIAP 658
CSCP +P +C PC G Y G +++C C G C+
Sbjct: 163 --CSCPSGL--------QPPNCLQ-PCTPG-----YYGPACQFRCQC----HGAPCDPQT 202
Query: 659 SPCFRSPCVNGG-----TCEDRDTDFFC----HCQAGYMGRRCQAEVDCGPPEEVKHATL 709
CF P G +C + FFC CQ G + + Q C P
Sbjct: 203 GACF-CPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGW------- 254
Query: 710 RFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQ 769
+G + C G+ HG P C + ECR C +GG C
Sbjct: 255 ------MGTICSLPCPEGF-------------HG-----PNCSQ--ECR---CHNGGLC- 284
Query: 770 DRVAGYLCLCSTGYEGAHCELE-------RDECRAHPCRNGGSCRNLPGAYVCR------ 816
DR G C C+ GY G C E +D C C GA +C
Sbjct: 285 DRFTGQ-CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGD 343
Query: 817 ------CPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDP 870
CP GF G+ C+ CD +H C G C C + G HC S P
Sbjct: 344 RCTDRLCPDGFYGLSCQAPC-TCDR---EHSLSCHPMNGE--CSCLPGWAGLHCNE-SCP 396
Query: 871 CFSSPCGGRGYCLASNG------SHSCTCKVGYTGEDCAKELFPP 909
+ G + +CL +G S C C GYTG CA L PP
Sbjct: 397 QDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCA-SLCPP 440
Score = 43.1 bits (100), Expect = 0.002
Identities = 18/38 (47%), Positives = 25/38 (65%), Gaps = 3/38 (7%)
Query: 1310 NCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
NCS C+NGGTC+P + +C C PGF+G C+ +C
Sbjct: 575 NCSNTCTCKNGGTCLP--ENGNCVCAPGFRGPSCQRSC 610
Score = 35.0 bits (79), Expect = 0.51
Identities = 21/70 (30%), Positives = 28/70 (40%), Gaps = 8/70 (11%)
Query: 1310 NCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELACI--KVSRPCTRLFS---ETKAF 1363
NCS+ C NGG C C C PG+ G RC C + + C + + F
Sbjct: 271 NCSQECRCHNGGLC--DRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCF 328
Query: 1364 PVWEGGVCHH 1373
P +C H
Sbjct: 329 PANGACLCEH 338
Score = 32.3 bits (72), Expect = 3.3
Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 1312 SENPCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
S + CQNGG V SC C PG+ G C L C
Sbjct: 231 STHSCQNGG--VFQTPQGSCSCPPGWMGTICSLPC 263
Score = 31.2 bits (69), Expect = 7.4
Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 7/43 (16%)
Query: 1307 VPGNC-SENPCQNGGTCVPG--ADAHSCDCGPGFKGRRCELAC 1346
V G C + N CQ CVPG D S +C PG G +C+ C
Sbjct: 110 VHGRCVAPNQCQ----CVPGWRGDDCSSECAPGMWGPQCDKPC 148
Score = 31.2 bits (69), Expect = 7.4
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 13/57 (22%)
Query: 1308 PGNCSEN-----PCQNGGTCVPGADAHSCDCGPGFKGRRCELAC------IKVSRPC 1353
PG+ EN C +GGTC P SC C G+ G C C S+PC
Sbjct: 654 PGHWGENCAQTCQCHHGGTCHP--QDGSCICPLGWTGHHCLEGCPLGTFGANCSQPC 708
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 192 bits (488), Expect = 2e-48
Identities = 197/747 (26%), Positives = 276/747 (36%), Gaps = 150/747 (20%)
Query: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFT---GRRCHLDVNECASQPCQNGGTCTH 328
C + + G+CID S+ C C +GF + LD+NEC C NG TC +
Sbjct: 1853 CQEIPNICSHGQCIDTV----GSFYCLCHTGFKTNDDQTMCLDINECERDACGNG-TCRN 1907
Query: 329 GINSFRCQCPAGFGGPTCETAQSPC-DTKECQHG-------GQCQVENGSAVCVCQAGYT 380
I SF C+C GF + + C D EC G GQC GS C C GY
Sbjct: 1908 TIGSFNCRCNHGF----ILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYE 1963
Query: 381 ----GAACEMDVDDCSPDP--CLNGGSCVDLVGNYTCLCAEPF--KGLRCETGDHPV--P 430
G C +D+++C +P C G +C +L G+Y C+C + + +CE D V P
Sbjct: 1964 VAPDGRTC-VDINECLLEPRKCAPG-TCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEP 2021
Query: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFM----GLDCRERVPDDCECR-NGGRCLGANT 485
+ C GTC + + + C CPEGF G C++ C + GG+C +
Sbjct: 2022 EICAL------GTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKS 2075
Query: 486 TL-----CQCPLGF--FGLLCEFEITAMPCNMNTQCPDG--------------------- 517
C C L +G CE T CP G
Sbjct: 2076 RNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPD 2135
Query: 518 ----GYCMEHGGSYLCVCHTDHNASHSLPSPCDS----DPCFNGGSCDAHDDSYTCECPR 569
G C+ GSY C C + + + D +PC NG +C + C C
Sbjct: 2136 VCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNG-TCKNVIGGFECTCEE 2194
Query: 570 GFHG---KHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRH----------CE 616
GF CE C+ P C G Y C CP + R CE
Sbjct: 2195 GFEPGPMMTCEDINE--CAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECE 2252
Query: 617 IGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGR----------HCEIAPSPCFRSPC 666
GK D C C + IG Y C C PG+ R C+ P C
Sbjct: 2253 EGKHD-CTEKQME----CKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC----- 2302
Query: 667 VNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPP----EEVKHATLRFNGTRLGAVALY 722
G C + + C C G+ Q E EV + + V
Sbjct: 2303 -ENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKS 2361
Query: 723 ACDRGYSLSAPSRIRVCQPHGVWSEPPQC----------LEIDECR--SQPCLHGGSCQD 770
C +C G + C +IDEC+ C +G D
Sbjct: 2362 ECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVND 2421
Query: 771 RVAGYLCLCSTGYE----GAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFV---- 822
R Y C+C TGY G C ++ +EC P C+N G+Y C CP G++
Sbjct: 2422 R-GSYHCICKTGYTPDITGTSC-VDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQED 2479
Query: 823 GVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETV-SDPCFS--SPCGGR 879
G C+ ++D C + C + G + C CP F +H + ++ C S + CG +
Sbjct: 2480 GRSCK-DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSK 2538
Query: 880 GYCLASNGSHSCTCKVGY----TGEDC 902
G C + GS +C C+ G+ TG C
Sbjct: 2539 GICQNTPGSFTCECQRGFSLDQTGSSC 2565
Score = 189 bits (481), Expect = 1e-47
Identities = 197/727 (27%), Positives = 278/727 (38%), Gaps = 137/727 (18%)
Query: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGF----TGRRCHLDVNECASQPCQNGGTCT 327
C L GGKCI+ S+ C C +G+ R C DVNEC + GTC
Sbjct: 1610 CQELPGLCQGGKCINTF----GSFQCRCPTGYYLNEDTRVCD-DVNECETPGICGPGTCY 1664
Query: 328 HGINSFRCQCPAGF----GGPTC-ETAQSPC------DTKECQHGGQCQVENGSAVCVCQ 376
+ + ++ C CP + GG C + +S C D + C G+ +C C
Sbjct: 1665 NTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD--GELLFNMTKKMCCCS 1722
Query: 377 AGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCE--TGDHPVPDACL 434
G A + C P P + + LC G + TG D C
Sbjct: 1723 YNI-GRAWNKPCEQC-PIPSTD---------EFATLCGSQRPGFVIDIYTGLPVDIDECR 1771
Query: 435 SAP--CHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCL-------GANT 485
P C NG C++ + CECP GF D D EC+NG C A +
Sbjct: 1772 EIPGVCENG-VCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGS 1830
Query: 486 TLCQCPLGFFGLLCEFEITAMPCNMNTQCPD------GGYCMEHGGSYLCVCHTDHNASH 539
C C G+ F T CN +C + G C++ GS+ C+CHT +
Sbjct: 1831 YRCDCKPGY-----RFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTND 1884
Query: 540 SLP-----SPCDSDPCFNGGSCDAHDDSYTCECPRGF---HGKHCEKARPHLCSSGP--- 588
+ C+ D C N G+C S+ C C GF H C C+SG
Sbjct: 1885 DQTMCLDINECERDACGN-GTCRNTIGSFNCRCNHGFILSHNNDCIDVDE--CASGNGNL 1941
Query: 589 CRNGGTCKEAGGEYHCSCPYRF----TGRHCE-----IGKPDSCASGPCHNGGTCFHYIG 639
CRN G C G + C C + GR C + +P CA G C N G
Sbjct: 1942 CRN-GQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQN------LDG 1994
Query: 640 KYKCDCPPGFS--GRHCEIAPSPCFRSPCVNG-GTCEDRDTDFFCHCQAGY----MGRRC 692
Y+C CPPG+S CE C P + GTC + + F C C G+ GRRC
Sbjct: 1995 SYRCICPPGYSLQNEKCEDI-DECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRC 2053
Query: 693 Q--------AEVD---CGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQP 741
Q A+ + C P+ H+ G C+ + + ++C P
Sbjct: 2054 QDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQIC-P 2112
Query: 742 HG---VWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGY--EGAHCELERDECR 796
+G + +++DEC+ G C + Y C C GY G C ++ DEC
Sbjct: 2113 YGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC-VDTDECS 2171
Query: 797 -AHPCRNGGSCRNLPGAYVCRCPAGFVG---VHCETEVDACDSSPCQHGGRCESGGGAYL 852
+PC N G+C+N+ G + C C GF + CE +++ C +P RC + G+Y
Sbjct: 2172 VGNPCGN-GTCKNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTYGSYE 2229
Query: 853 CVCPESFF----------GYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY----T 898
C CP + CE C + C G++ C C GY
Sbjct: 2230 CKCPVGYVLREDRRMCKDEDECEEGKHDCTEK----QMECKNLIGTYMCICGPGYQRRPD 2285
Query: 899 GEDCAKE 905
GE C E
Sbjct: 2286 GEGCVDE 2292
Score = 187 bits (474), Expect = 8e-47
Identities = 218/861 (25%), Positives = 295/861 (34%), Gaps = 281/861 (32%)
Query: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQC 337
C+NGG C DD C C G+ G C V E C NGG C + RC C
Sbjct: 123 CMNGGSCSDD--------HCLCQKGYIGTHCGQPVCESG---CLNGGRC---VAPNRCAC 168
Query: 338 PAGFGGPTCET--AQSPCDTKECQHGGQCQVENGSAVCV--------------------- 374
GF GP CE PC T CQ + VC
Sbjct: 169 TYGFTGPQCERDYRTGPCFTVISNQ--MCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPA 226
Query: 375 ----CQAGY-----TGAACEMDVDDCSPDPCL-NGGSCVDLVGNYTCLCAEPFK----GL 420
C+ G+ TGA DVD+C P L GG+C++ VG++ C C K
Sbjct: 227 QPHPCRRGFIPNIRTGAC--QDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQ 284
Query: 421 RCETGDH--PVPDACLSAPCHNGGTCVDADQGYVCECPEGFM----GLDCRERVPDDCE- 473
+CE D +P C GG C + Y C+CP GF G C + P C
Sbjct: 285 KCEDIDECSTIPGIC------EGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYT 338
Query: 474 --------------------CRNGGRCLGANTTLC--QCPLGF---FGLLCEFEIT---- 504
C + GRC T+ CP+ F LC +
Sbjct: 339 ALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGR 398
Query: 505 ---------------------------------------------AMPCNMNTQCP---- 515
+P N+ C
Sbjct: 399 PEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRY 458
Query: 516 --DGGYCMEHGGSYLCVCHT----DHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPR 569
G C+ GS C C+ D C+ +PC GG C + SYTC+C
Sbjct: 459 LCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINNQGSYTCQCRA 517
Query: 570 GFHGK----HCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRF----TGRHCEIGKPD 621
G+ C L + C NG C G +HC C F G++CE D
Sbjct: 518 GYQSTLTRTECRDIDECLQNGRICNNG-RCINTDGSFHCVCNAGFHVTRDGKNCE--DMD 574
Query: 622 SCASGPCHNGGTCFHYIGKYKCDCPPGFS----GRHCEIAPSPCFRSPCVNGGTCEDRDT 677
C+ G C + G +KC C PGF GR+C+ C+NG C + D
Sbjct: 575 ECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNG-RCVNTDG 633
Query: 678 DFFCHC----QAGYMGRRCQAEVDCGPPEEVKHATLRFNGTR--LGAVALYAC---DRGY 728
+ C C G GR C VD R + GAV C Y
Sbjct: 634 SYRCECFPGLAVGLDGRVC---VDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEY 690
Query: 729 SLSAPSRIRVCQP---------HGVWSEPPQCL----EIDECRSQPCL-HGGSCQDRVAG 774
+ P CQP + S P +I+EC P + G C++
Sbjct: 691 AFGEP-----CQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGT 745
Query: 775 YLCLCSTGYE----GAHCELERDECRAHP--CRNGGSCRNLPGAYVCRCPAGFVGVH--- 825
Y C+C++GYE G +C ++ +EC + C NG CRN PG++VC CP GF+
Sbjct: 746 YKCICNSGYEVDSTGKNC-VDINECVLNSLLCDNG-QCRNTPGSFVCTCPKGFIYKPDLK 803
Query: 826 -CETEVDACDSSPCQHGGRCESGGGAYLC-------------VCPESFFGYHCETVSD-- 869
CE ++D C+SSPC +G C++ G+++C +C E+ G +TV D
Sbjct: 804 TCE-DIDECESSPCINGV-CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGR 861
Query: 870 -------------------PCFSSPCG--------GRGY--------------------- 881
+ SPC G+GY
Sbjct: 862 CEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVC 921
Query: 882 ----CLASNGSHSCTCKVGYT 898
C+ + GS C C G T
Sbjct: 922 KNGLCVNTRGSFKCQCPSGMT 942
Score = 186 bits (473), Expect = 1e-46
Identities = 208/765 (27%), Positives = 297/765 (38%), Gaps = 160/765 (20%)
Query: 267 HTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTG--RRCHLDVNECASQPCQNGG 324
+ T C +R G+CI S C C GF R +DV+EC PC GG
Sbjct: 448 NVTDYCQLVRYLCQNGRCIPT----PGSCRCECNKGFQLDLRGECIDVDECEKNPCA-GG 502
Query: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKEC-QHG-----GQCQVENGSAVCVCQAG 378
C + S+ CQC AG+ T D EC Q+G G+C +GS CVC AG
Sbjct: 503 ECINNQGSYTCQCRAGYQSTLTRTECR--DIDECLQNGRICNNGRCINTDGSFHCVCNAG 560
Query: 379 Y----TGAACEMDVDDCS-PDPCLNGGSCVDLVGNYTCLCAEPFK----GLRC-ETGDHP 428
+ G CE D+D+CS + CLN G C++ G++ C+C F+ G C + +
Sbjct: 561 FHVTRDGKNCE-DMDECSIRNMCLN-GMCINEDGSFKCICKPGFQLASDGRYCKDINECE 618
Query: 429 VPDACLSAPCHNGGTCVDADQGYVCECPEGF-MGLDCRERVPDDCE--CRNG---GRCL- 481
P C++ G CV+ D Y CEC G +GLD R V C G G+C+
Sbjct: 619 TPGICMN------GRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIK 672
Query: 482 ---GANT---TLCQCPLGFFGLLCE-------FEITAM---------------PCNMNTQ 513
GA T C FG C+ E A+ C ++
Sbjct: 673 PLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPD 732
Query: 514 CPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCF------NGGSCDAHDDSYTCEC 567
G C G+Y C+C++ + + + D + C + G C S+ C C
Sbjct: 733 ICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTC 792
Query: 568 PRGFHGKHCEKARPHL--CSSGPCRNGGTCKEAGGEYHCSCPYRFT-------------- 611
P+GF K K + C S PC N G CK + G + C C T
Sbjct: 793 PKGFIYKPDLKTCEDIDECESSPCIN-GVCKNSPGSFICECSSESTLDPTKTICIETIKG 851
Query: 612 --------GRHCEIG------KPDSCASGPCHNGGTCFHYIGKYKCDCPPGFS---GRHC 654
GR CEI K C+S G C + + C G+S G C
Sbjct: 852 TCWQTVIDGR-CEININGATLKSQCCSSLGAAWGSPC--TLCQVDPICGKGYSRIKGTQC 908
Query: 655 E-IAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGY----MGRRC-----------QAEVDC 698
E I F C N G C + F C C +G GR C + +C
Sbjct: 909 EDIDECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEEC 967
Query: 699 GPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHG-------VWSEPPQC 751
P +H + A C+ + P +C P G + + P
Sbjct: 968 TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELC-PRGPGFATKEITNGKPFF 1026
Query: 752 LEIDECRSQP--CLHGGSCQDRVAGYLCLCSTGY----EGAHCELERDECRAHPCRNG-G 804
+I+EC+ P C H G C++ + + C C +G+ E +C + DECR P G G
Sbjct: 1027 KDINECKMIPSLCTH-GKCRNTIGSFKCRCDSGFALDSEERNC-TDIDECRISPDLCGRG 1084
Query: 805 SCRNLPGAYVCRC----PAGFVGVHCETEVDACDSSPCQ-HGGRCESGGGAYLCVCPESF 859
C N PG + C+C +GF+ + ++D C P GG C + G+Y C CP
Sbjct: 1085 QCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPP-- 1142
Query: 860 FGYH-------CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 897
G+ C +++ S+ G C+ G + C C GY
Sbjct: 1143 -GHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 1186
Score = 185 bits (470), Expect = 2e-46
Identities = 190/745 (25%), Positives = 273/745 (36%), Gaps = 148/745 (19%)
Query: 272 CLALRPCL--NGGKCID-DCVTGNPSYTCSCLSGFT----GRRCHLDVNECASQPCQNG- 323
C+ + C NG C + C+ S+ C C G+ GR C +D+NEC +P +
Sbjct: 1928 CIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAP 1986
Query: 324 GTCTHGINSFRCQCPAGFG--GPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTG 381
GTC + S+RC CP G+ CE + E G C GS C+C G++
Sbjct: 1987 GTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSL 2046
Query: 382 AACEMDVDDCSPDPC---LNGGSCVDLVGN----YTCLCA---------------EPFKG 419
++ D C GG C C CA EP +
Sbjct: 2047 SSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEA 2106
Query: 420 LR--CETGDHPVP---------DACLSAPCHNGGTCVDADQGYVCECPEGFM--GLDCRE 466
R C G + D C G C++ D Y CECP G++ G +C
Sbjct: 2107 FRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC-- 2164
Query: 467 RVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCE--FEI-TAMPCNMNTQCPDGGY---- 519
D EC G C N T C+ +G F CE FE M C +C
Sbjct: 2165 --VDTDECSVGNPC--GNGT-CKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAF 2219
Query: 520 -CMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGG--------SCDAHDDSYTCECPRG 570
C+ GSY C C + D D C G C +Y C C G
Sbjct: 2220 RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPG 2279
Query: 571 FH----GKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGR----HCEIGKPDS 622
+ G+ C G C NG C G Y C C FT C +
Sbjct: 2280 YQRRPDGEGCVDENECQTKPGICENG-RCLNTRGSYTCECNDGFTASPNQDECLDNREGY 2338
Query: 623 CAS----GPCHNGGTCFHYIGKYKCDCPPGFS-GRHCEIAP---SPCFRSPCVNG----- 669
C + C G + + + K +C C G G HCEI P + F+ C +G
Sbjct: 2339 CFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMT 2398
Query: 670 -----------------GTCEDRDTDFFCHCQAGYM----GRRCQAEVDCGP-PEEVKHA 707
G C + + C C+ GY G C +C P+
Sbjct: 2399 NGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFI 2458
Query: 708 TLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGS 767
G+ +C +GY L R C ++DEC ++
Sbjct: 2459 CKNTEGSYQ-----CSCPKGYILQEDGR--------------SCKDLDECATKQHNCQFL 2499
Query: 768 CQDRVAGYLCLCSTGYEGAHCE-LERDECRA--HPCRNGGSCRNLPGAYVCRCPAGF--- 821
C + + G+ C C G+ H ++ +EC + + C + G C+N PG++ C C GF
Sbjct: 2500 CVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLD 2559
Query: 822 -VGVHCETEVDACDSSP-CQHGGRCESGGGAYLCVCPESFFGYH----CETVSDPCFSSP 875
G CE +VD C+ + CQHG C++ G Y C CP+ + ++ C ++ +
Sbjct: 2560 QTGSSCE-DVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHI 2616
Query: 876 CGGRGYCLASNGSHSCTCKVGYTGE 900
CGG C + GS+ C C G+ E
Sbjct: 2617 CGGAS-CHNTLGSYKCMCPAGFQYE 2640
Score = 182 bits (461), Expect = 3e-45
Identities = 189/729 (25%), Positives = 274/729 (37%), Gaps = 160/729 (21%)
Query: 288 CVTGNPSYTCSCLSGFTGRRCHLDVNECASQP--CQNGGTCTHGINSFRCQCPAGFGGP- 344
C + P + +G +D++EC P C+NG C + + SFRC+CP GF
Sbjct: 1748 CGSQRPGFVIDIYTGLP-----VDIDECREIPGVCENG-VCINMVGSFRCECPVGFFYND 1801
Query: 345 ---TCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY--TGAACEMDVDDCSPDPCL-N 398
CE + CQ +C GS C C+ GY T D ++C P + +
Sbjct: 1802 KLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICS 1861
Query: 399 GGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEG 458
G C+D VG++ CLC FK +T + + C C NG TC + + C C G
Sbjct: 1862 HGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINE-CERDACGNG-TCRNTIGSFNCRCNHG 1919
Query: 459 FM---GLDCRERVPDDCECRNG-----GRCLGA-NTTLCQCPLGFF----GLLCEFEITA 505
F+ DC + D+C NG G+C+ + CQC G+ G C +
Sbjct: 1920 FILSHNNDCID--VDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC---VDI 1974
Query: 506 MPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNG------GSCDAH 559
C + + G C GSY C+C ++ + D D C G+C
Sbjct: 1975 NECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCE--DIDECVEEPEICALGTCSNT 2032
Query: 560 DDSYTCECPRGFH----GKHCEKARPHLC----SSGPCRNGGTCKEAGGEYHCSCPYRFT 611
+ S+ C CP GF G+ C+ R C G C + + + E C+
Sbjct: 2033 EGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGW 2092
Query: 612 GRHCEI--GKPDSCASGPCHNG-------------------------GTCFHYIGKYKCD 644
G CE+ +PD C G G C + G Y+C+
Sbjct: 2093 GDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCE 2152
Query: 645 CPPGF--SGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPE 702
CP G+ +G C +PC NG TC++ F C C+ G+ + C
Sbjct: 2153 CPFGYILAGNECVDTDECSVGNPCGNG-TCKNVIGGFECTCEEGF---EPGPMMTCEDIN 2208
Query: 703 EVKHATLRFNGTRLGAVALYACDR--GYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRS- 759
E L + Y C GY L R+ C + DEC
Sbjct: 2209 ECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRM--------------CKDEDECEEG 2254
Query: 760 -QPCLHGG-SCQDRVAGYLCLCSTGYE----GAHCELERDECRAHP--CRNGGSCRNLPG 811
C C++ + Y+C+C GY+ G C ++ +EC+ P C NG C N G
Sbjct: 2255 KHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGC-VDENECQTKPGICENG-RCLNTRG 2312
Query: 812 AYVCRCPAGFVGV------------HCETEV--DACD-----------SSPCQHGGR--- 843
+Y C C GF +C TEV + C S C GGR
Sbjct: 2313 SYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWG 2372
Query: 844 --CE----SGGGAYLCVCPESFFGY--------HCETVSDPCFSSPCGGRGYCLASNGSH 889
CE G A+ +CP G+ C+ + D C + G C+ GS+
Sbjct: 2373 PHCEICPFQGTVAFKKLCPHGR-GFMTNGADIDECKVIHDVCRN------GECVNDRGSY 2425
Query: 890 SCTCKVGYT 898
C CK GYT
Sbjct: 2426 HCICKTGYT 2434
Score = 181 bits (459), Expect = 4e-45
Identities = 182/659 (27%), Positives = 245/659 (37%), Gaps = 168/659 (25%)
Query: 288 CVTGNPSYTCSCLSGF--TGRRCHLDVNECA-SQPCQNGGTCTHGINSFRCQCPAGFG-G 343
C+ + SY C C G+ G C +D +EC+ PC NG TC + I F C C GF G
Sbjct: 2142 CINTDGSYRCECPFGYILAGNEC-VDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPG 2199
Query: 344 P--TCETAQSPCDTKECQHGG-----QCQVENGSAVCVCQAGYT----------GAACEM 386
P TCE D EC +C GS C C GY CE
Sbjct: 2200 PMMTCE------DINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEE 2253
Query: 387 DVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPD-ACLSAP--CHNGGT 443
DC+ C +L+G Y C+C ++ R G+ V + C + P C NG
Sbjct: 2254 GKHDCTEKQM----ECKNLIGTYMCICGPGYQ--RRPDGEGCVDENECQTKPGICENG-R 2306
Query: 444 CVDADQGYVCECPEGFMGLDCRERVPDDCE-----------CRNGGRCLGANT-TLCQCP 491
C++ Y CEC +GF ++ D+ E C+ G T + C C
Sbjct: 2307 CLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCD 2366
Query: 492 LGF-FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPC 550
G +G CE CP G M +G + C H D C
Sbjct: 2367 GGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGAD-IDECKVIH------------DVC 2413
Query: 551 FNGGSCDAHDDSYTCECPRGFH----GKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSC 606
NG C SY C C G+ G C C+ P CK G Y CSC
Sbjct: 2414 RNG-ECVNDRGSYHCICKTGYTPDITGTSCVDLNE--CNQAPKPCNFICKNTEGSYQCSC 2470
Query: 607 PYRFT----GRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCE-IAPSPC 661
P + GR C+ D CA+ + C + IG + C CPPGF+ H I + C
Sbjct: 2471 PKGYILQEDGRSCK--DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNEC 2528
Query: 662 FR--SPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAV 719
+ C + G C++ F C CQ
Sbjct: 2529 TSDINLCGSKGICQNTPGSFTCECQ----------------------------------- 2553
Query: 720 ALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECR-SQPCLHGGSCQDRVAGYLCL 778
RG+SL C ++DEC + C HG CQ+ + GY C
Sbjct: 2554 ------RGFSLDQTGS--------------SCEDVDECEGNHRCQHG--CQNIIGGYRCS 2591
Query: 779 CSTGY----EGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGF----VGVHCETEV 830
C GY + C E + AH C G SC N G+Y C CPAGF C+ ++
Sbjct: 2592 CPQGYLQHYQWNQCVDENECLSAHIC-GGASCHNTLGSYKCMCPAGFQYEQFSGGCQ-DI 2649
Query: 831 DACDS--SPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNG 887
+ C S +PC +G C + G YLC CP +F G+G+C++ G
Sbjct: 2650 NECGSAQAPCSYG--CSNTEGGYLCGCPPGYFRI---------------GQGHCVSGMG 2691
Score = 172 bits (437), Expect = 2e-42
Identities = 189/783 (24%), Positives = 281/783 (35%), Gaps = 188/783 (24%)
Query: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQP--CQNGGTCTHG 329
C A G C + Y C SG D+NECA P C NG C +
Sbjct: 684 CCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNG-ICENL 742
Query: 330 INSFRCQCPAGFGGPTCETAQSPCDTKECQ------HGGQCQVENGSAVCVCQAGYTGA- 382
+++C C +G+ T ++ D EC GQC+ GS VC C G+
Sbjct: 743 RGTYKCICNSGY--EVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKP 800
Query: 383 ---ACEMDVDDCSPDPCLNGGSCVDLVGNYTC-------------LCAEPFKGL------ 420
CE D+D+C PC+NG C + G++ C +C E KG
Sbjct: 801 DLKTCE-DIDECESSPCING-VCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVI 858
Query: 421 --RCETGDH--PVPDACLSA-------PCH------------------------------ 439
RCE + + C S+ PC
Sbjct: 859 DGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFP 918
Query: 440 ---NGGTCVDADQGYVCECPEGFMGLDCRERV--------------PDDCECRNGGR--- 479
G CV+ + C+CP G M LD R+ ++C GR
Sbjct: 919 GVCKNGLCVNTRGSFKCQCPSG-MTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRM 977
Query: 480 -----CLGA--NTTLCQ-CPLGF---FGLLCEF-------EIT--------AMPCNMNTQ 513
+GA T C+ CP+ + LC EIT C M
Sbjct: 978 DACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPS 1037
Query: 514 CPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPC------FNGGSCDAHDDSYTCEC 567
G C GS+ C C + + D D C G C + C+C
Sbjct: 1038 LCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKC 1097
Query: 568 PRGFHG-----KHCEKARPHLCSSGP--CRNGGTCKEAGGEYHCSCP--YRFTGRHCEIG 618
G+ K+C C P CR GG C G Y C CP ++ +
Sbjct: 1098 DEGYESGFMMMKNCMDIDE--CQRDPLLCR-GGVCHNTEGSYRCECPPGHQLSPNISACI 1154
Query: 619 KPDSC--ASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGT---CE 673
+ C ++ C NG C + IGKY+C C PG+ + +NGG C
Sbjct: 1155 DINECELSAHLCPNG-RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCT 1213
Query: 674 DRDTDFFCHCQAGYM----GRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYS 729
+ + + C CQ G+ R C +C + CD G
Sbjct: 1214 NSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNI-------------------CDGGQC 1254
Query: 730 LSAPSRIR-VCQPHGVWSEPPQ-CLEIDECRSQP--CLHGGSCQDRVAGYLCLCSTGYEG 785
+ P R +C + SE + C++++EC P CL G+C++ ++C C GY G
Sbjct: 1255 TNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICL-SGTCENTKGSFICHCDMGYSG 1313
Query: 786 AH-----CELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVG--VHCETEVDACDSSP- 837
++ E AH C C N G++ C C G++G + C T++D C +
Sbjct: 1314 KKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKC-TDLDECSNGTH 1372
Query: 838 -CQHGGRCESGGGAYLCVCPESFFG--YHCETVSDPCFSSPCGGRGYCLASNGSHSCTCK 894
C C++ G+Y C+C E + G + C + + + G G CL + G + C C
Sbjct: 1373 MCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECD 1432
Query: 895 VGY 897
+G+
Sbjct: 1433 MGF 1435
Score = 168 bits (425), Expect = 4e-41
Identities = 187/713 (26%), Positives = 271/713 (38%), Gaps = 129/713 (18%)
Query: 271 VCLALRPCLNGGKCID--DCVTGNPSYTCSCLSGF----TGRRCHLDVNECASQP--CQN 322
VC + C NG C +C+ SY C C G+ TG+ C+ D NEC P C +
Sbjct: 1805 VCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQ-CN-DRNECQEIPNICSH 1862
Query: 323 GGTCTHGINSFRCQCPAGFGGPTCETAQSPC-DTKECQH----GGQCQVENGSAVCVCQA 377
G C + SF C C GF Q+ C D EC+ G C+ GS C C
Sbjct: 1863 G-QCIDTVGSFYCLCHTGF---KTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNH 1918
Query: 378 GYTGAACE--MDVDDCSP---DPCLNGGSCVDLVGNYTCLCAEPFK----GLRCETGDHP 428
G+ + +DVD+C+ + C NG C++ VG++ C C E ++ G C +
Sbjct: 1919 GFILSHNNDCIDVDECASGNGNLCRNG-QCINTVGSFQCQCNEGYEVAPDGRTCVDINEC 1977
Query: 429 VPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLC 488
+ + AP GTC + D Y C CP G+ + E+ D EC T C
Sbjct: 1978 LLEPRKCAP----GTCQNLDGSYRCICPPGYSLQN--EKCEDIDECVEEPEICALGT--C 2029
Query: 489 QCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCME--HGGSYLCVCHTDHNASHSLPSPCD 546
G F LC + Q YC GG C + + +HS C
Sbjct: 2030 SNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGK----CSSPKSRNHSKQECCC 2085
Query: 547 S-------DPCFNGGSCDAH-DDSYTCECPRG---FHGKHCEKARPHLCSSGPCRNGGTC 595
+ DPC C D+++ CP G G C G C
Sbjct: 2086 ALKGEGWGDPC---ELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQC 2142
Query: 596 KEAGGEYHCSCPYRFTGRHCEIGKPDSCASG-PCHNGGTCFHYIGKYKCDCPPGFSG--- 651
G Y C CP+ + E D C+ G PC N GTC + IG ++C C GF
Sbjct: 2143 INTDGSYRCECPFGYILAGNECVDTDECSVGNPCGN-GTCKNVIGGFECTCEEGFEPGPM 2201
Query: 652 RHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYM----GRRCQAEVDCGPPEEVKHA 707
CE + C ++P + C + + C C GY+ R C+ E +C EE KH
Sbjct: 2202 MTCEDI-NECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDEC---EEGKHD 2257
Query: 708 TLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEP--PQCLEIDECRSQPCL-H 764
+ Y C +C P G P C++ +EC+++P +
Sbjct: 2258 CTEKQMECKNLIGTYMC-------------ICGP-GYQRRPDGEGCVDENECQTKPGICE 2303
Query: 765 GGSCQDRVAGYLCLCSTGYEGA----HCELERD-----ECRAHPCRNGGSCRNLPGAYVC 815
G C + Y C C+ G+ + C R+ E + C+ G S RN C
Sbjct: 2304 NGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSEC 2363
Query: 816 RCPAG-FVGVHCE------------------------TEVDACD--SSPCQHGGRCESGG 848
C G G HCE ++D C C++ G C +
Sbjct: 2364 CCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRN-GECVNDR 2422
Query: 849 GAYLCVCPESF----FGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 897
G+Y C+C + G C +++ C +P C + GS+ C+C GY
Sbjct: 2423 GSYHCICKTGYTPDITGTSCVDLNE-CNQAPKPCNFICKNTEGSYQCSCPKGY 2474
Score = 165 bits (418), Expect = 3e-40
Identities = 184/737 (24%), Positives = 265/737 (35%), Gaps = 154/737 (20%)
Query: 279 LNGGKCIDDCVT------GNPSYTCS----CLSGFT---GRRCHLDVNECASQP--CQNG 323
+NG C + G+P C C G++ G +C D++EC P C+NG
Sbjct: 866 INGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE-DIDECEVFPGVCKNG 924
Query: 324 GTCTHGINSFRCQCPAGFG-----------------------------------GPTCET 348
C + SF+CQCP+G C +
Sbjct: 925 -LCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCS 983
Query: 349 AQSPCDTKECQHGGQCQVENGSAVCVCQAGYT------GAACEMDVDDCSPDPCL-NGGS 401
+ T+EC+ +C G+ G D+++C P L G
Sbjct: 984 VGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGK 1043
Query: 402 CVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNG-GTCVDADQGYVCECPEGFM 460
C + +G++ C C F L E + D C +P G G CV+ + C+C EG+
Sbjct: 1044 CRNTIGSFKCRCDSGF-ALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE 1102
Query: 461 G--------LDCRERVPDDCECRNGGRCLGANTTL-CQCPLGF-FGLLCEFEITAMPCNM 510
+D E D CR GG C + C+CP G I C +
Sbjct: 1103 SGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQLSPNISACIDINECEL 1161
Query: 511 NTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPC--FNGGS---CDAHDDSYTC 565
+ G C+ G Y C C+ ++++ D D C NGG C + SY C
Sbjct: 1162 SAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYEC 1221
Query: 566 ECPRGFHGKHCEKARPHL--CSSGP--CRNGGTCKEAGGEYHCSCPYRFTG--------- 612
C GF +++ + C P C +GG C GEY C C F
Sbjct: 1222 SCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQCTNIPGEYRCLCYDGFMASEDMKTCVD 1280
Query: 613 -RHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGR----------HCEIAPSPC 661
C++ P+ C SG C N G + C C G+SG+ CEI C
Sbjct: 1281 VNECDLN-PNICLSGTCENTK------GSFICHCDMGYSGKKGKTGCTDINECEIGAHNC 1333
Query: 662 FRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVAL 721
+ C + F C C G++G + C +E NGT +
Sbjct: 1334 GKH-----AVCTNTAGSFKCSCSPGWIGDG----IKCTDLDECS------NGTHM----- 1373
Query: 722 YACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHG-GSCQDRVAGYLCLCS 780
+ R G + C ++DEC L G G C + GY C C
Sbjct: 1374 -CSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECD 1432
Query: 781 TGY----EGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFV----GVHCETEVDA 832
G+ +G CE + DEC G+C NLPG + C C G+ G +C T+V+
Sbjct: 1433 MGFVPSADGKACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNC-TDVNE 1490
Query: 833 CDSSPCQHGGRCESGGGAYLCVCPESF----FGYHC-ETVSDPCFSS--PCGGRGYCLAS 885
C G C + G+Y+C CP F C +T S C+ P G G S
Sbjct: 1491 CLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACS 1550
Query: 886 N------GSHSCTCKVG 896
N SC C +G
Sbjct: 1551 NEIGVGVSKASCCCSLG 1567
Score = 164 bits (414), Expect = 7e-40
Identities = 189/737 (25%), Positives = 263/737 (35%), Gaps = 202/737 (27%)
Query: 272 CLALRPCLNGGKCID---DCVTGNPSYTCSCLSGFTGR--RCHLDVNECAS--QPCQNGG 324
C L C NG DC SY C C G+TG C D++EC+ C N G
Sbjct: 1361 CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTC-TDLDECSENLNLCGN-G 1418
Query: 325 TCTHGINSFRCQCPAGF----GGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY- 379
C + +RC+C GF G CE C G C G C C+ GY
Sbjct: 1419 QCLNAPGGYRCECDMGFVPSADGKACEDIDE-CSLPNICVFGTCHNLPGLFRCECEIGYE 1477
Query: 380 ---TGAACEMDVDDC-SPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLS 435
+G C DV++C P C++ G+CV+ G+Y C C F+ G
Sbjct: 1478 LDRSGGNC-TDVNECLDPTTCIS-GNCVNTPGSYICDCPPDFELNPTRVG---------- 1525
Query: 436 APCHNGGTCVDADQG--YVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLG 493
CVD G Y+ P G G D C N +G + C C LG
Sbjct: 1526 --------CVDTRSGNCYLDIRPRGDNG---------DTACSN-EIGVGVSKASCCCSLG 1567
Query: 494 -FFGLLCEFEITAMPCNMNTQCP---------------------------DGGYCMEHGG 525
+G CE CP GG C+ G
Sbjct: 1568 KAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFG 1627
Query: 526 SYLCVCHTDHNASHSL-----PSPCDSDPCFNGGSCDAHDDSYTCECPRGF----HGKHC 576
S+ C C T + + + C++ G+C +YTC CP + G +C
Sbjct: 1628 SFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNC 1687
Query: 577 EKARPHLCSSGPCRNGGTCKEAGGEY-------HCSCPY---RFTGRHCE---------- 616
R LC + TC GE C C Y R + CE
Sbjct: 1688 MDMRRSLCYRNYYADNQTC---DGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEF 1744
Query: 617 ----------------IGKP---DSCAS--GPCHNGGTCFHYIGKYKCDCPPGFSGRHCE 655
G P D C G C N G C + +G ++C+CP GF
Sbjct: 1745 ATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFRCECPVGFFYNDKL 1803
Query: 656 IAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTR 715
+ CED D CQ G + CQ +C
Sbjct: 1804 L--------------VCEDID-----ECQNGPV---CQRNAEC----------------- 1824
Query: 716 LGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP--CLHGGSCQDRVA 773
+ Y CD C+P ++ QC + +EC+ P C H G C D V
Sbjct: 1825 INTAGSYRCD-------------CKPGYRFTSTGQCNDRNECQEIPNICSH-GQCIDTVG 1870
Query: 774 GYLCLCSTGYEGAHCE---LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCE--T 828
+ CLC TG++ + L+ +EC C N G+CRN G++ CRC GF+ H
Sbjct: 1871 SFYCLCHTGFKTNDDQTMCLDINECERDACGN-GTCRNTIGSFNCRCNHGFILSHNNDCI 1929
Query: 829 EVDACDS---SPCQHGGRCESGGGAYLCVCPESF----FGYHCETVSDPCFSSPCGGRGY 881
+VD C S + C++ G+C + G++ C C E + G C +++ G
Sbjct: 1930 DVDECASGNGNLCRN-GQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGT 1988
Query: 882 CLASNGSHSCTCKVGYT 898
C +GS+ C C GY+
Sbjct: 1989 CQNLDGSYRCICPPGYS 2005
Score = 162 bits (409), Expect = 3e-39
Identities = 199/781 (25%), Positives = 281/781 (35%), Gaps = 194/781 (24%)
Query: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFT----GRRCHLDVNECASQPCQNGGTCT 327
C CLNG C+ + S+ C C GF GR C D+NEC + G C
Sbjct: 576 CSIRNMCLNGM-----CINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMNGRCV 629
Query: 328 HGINSFRCQC----PAGFGGPTC--------------------------ETAQSPCDTKE 357
+ S+RC+C G G C ++ C + E
Sbjct: 630 NTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTE 689
Query: 358 CQHGGQCQ---VENGS---AVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTC 411
G CQ +N + A+C G T A +++ PD C N G C +L G Y C
Sbjct: 690 YAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN-GICENLRGTYKC 748
Query: 412 LCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFM---GLDCRERV 468
+C ++ + + L++ + G C + +VC CP+GF+ L E +
Sbjct: 749 ICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDI 808
Query: 469 PDDCE---CRNGGRCLGANTTLCQC----PLGFFGLLC---------------EFEITAM 506
D+CE C NG + +C+C L +C EI
Sbjct: 809 -DECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININ 867
Query: 507 PCNMNTQCPDGGYCMEHG---GSYLCVCHTD----HNASHSLPSPC-DSDPC--FNG--- 553
+ +QC C G GS +C D S + C D D C F G
Sbjct: 868 GATLKSQC-----CSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCK 922
Query: 554 -GSCDAHDDSYTCECPRGF----HGKHCEKARPHLC------------SSGPCRNGGTCK 596
G C S+ C+CP G G+ C R C +G R C
Sbjct: 923 NGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCC 982
Query: 597 EAG---GEYHC-SCPYRFTGRHCEI--------------GKP-----DSCASGP--CHNG 631
G G C CP R T + E+ GKP + C P C +
Sbjct: 983 SVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTH- 1041
Query: 632 GTCFHYIGKYKCDCPPGFS----------GRHCEIAPSPCFRSPCVNGGTCEDRDTDFFC 681
G C + IG +KC C GF+ C I+P C R CVN DF C
Sbjct: 1042 GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVN------TPGDFEC 1095
Query: 682 HCQAGY-----MGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRI 736
C GY M + C +C + L G Y C+
Sbjct: 1096 KCDEGYESGFMMMKNCMDIDEC-----QRDPLLCRGGVCHNTEGSYRCE----------- 1139
Query: 737 RVCQP-HGVWSEPPQCLEIDECR-SQPCLHGGSCQDRVAGYLCLCSTGYEGAHCEL---E 791
C P H + C++I+EC S G C + + Y C C+ GY L +
Sbjct: 1140 --CPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVD 1197
Query: 792 RDECRAHPCRNGGS---CRNLPGAYVCRCPAGFVGVHCE---TEVDACDSSP--CQHGGR 843
DEC NGG C N G+Y C C GF + + T++D C+ +P C GG+
Sbjct: 1198 IDEC---SIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD-GGQ 1253
Query: 844 CESGGGAYLCVCPESFFGYH----CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTG 899
C + G Y C+C + F C V++ + G C + GS C C +GY+G
Sbjct: 1254 CTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSG 1313
Query: 900 E 900
+
Sbjct: 1314 K 1314
Score = 151 bits (382), Expect = 4e-36
Identities = 166/641 (25%), Positives = 230/641 (35%), Gaps = 117/641 (18%)
Query: 313 NECASQPCQNGGTCTHGINSF--RCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGS 370
N+C C++ +C G S C CP+G P+C + C +GG C ++
Sbjct: 78 NQCIVPICRH--SCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDH-- 133
Query: 371 AVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVP 430
C+CQ GY G C V + CLNGG C V C C F G +CE
Sbjct: 134 --CLCQKGYIGTHCGQPVCESG---CLNGGRC---VAPNRCACTYGFTGPQCERD----- 180
Query: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLC-- 488
+ G C +C+ G+ C + + C C GR G +C
Sbjct: 181 --------YRTGPCFTVISNQMCQ--GQLSGIVCTKTL---C-CATVGRAWGHPCEMCPA 226
Query: 489 ---QCPLGFFGLLCEFEITAMPCNMNTQCP------DGGYCMEHGGSYLCVCHTDHNASH 539
C GF I C +C GG C+ GS+ C C H +
Sbjct: 227 QPHPCRRGFIP-----NIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNE 281
Query: 540 SLPSPCDSDPC------FNGGSCDAHDDSYTCECPRGFH----GKHCEKARPHLC----S 585
D D C GG C SY C+CP GF+ G C RP C +
Sbjct: 282 VSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALT 341
Query: 586 SGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIG---KPDSCASGPCHNGGTCFHYIGKYK 642
+G C N ++ + C C GR G P+ C + F+ +
Sbjct: 342 NGRCSN--QLPQSITKMQCCCD---AGRCWSPGVTVAPEMCPIRATED----FNKL---- 388
Query: 643 CDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPE 702
C P GR E P P P V G + V+ P
Sbjct: 389 CSVPMVIPGRP-EYPPPPLGPIPPV---------LPVPPGFPPGPQIPVPRPPVEYLYPS 438
Query: 703 EVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRV-CQPHGVWSEPPQCLEIDECRSQP 761
L N T + Y C G + P R C +C+++DEC P
Sbjct: 439 REPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNP 498
Query: 762 CLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECR--------AHPCRNGGSCRNLPGAY 813
C GG C + Y C C GY+ L R ECR C N G C N G++
Sbjct: 499 CA-GGECINNQGSYTCQCRAGYQST---LTRTECRDIDECLQNGRIC-NNGRCINTDGSF 553
Query: 814 VCRCPAGF----VGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESF----FGYHCE 865
C C AGF G +CE ++D C G C + G++ C+C F G +C+
Sbjct: 554 HCVCNAGFHVTRDGKNCE-DMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK 612
Query: 866 TVSDPCFSSPCGGRGYCLASNGSHSCTC----KVGYTGEDC 902
+++ C + G C+ ++GS+ C C VG G C
Sbjct: 613 DINE-CETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVC 652
Score = 98.6 bits (244), Expect = 4e-20
Identities = 98/362 (27%), Positives = 139/362 (38%), Gaps = 95/362 (26%)
Query: 582 HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKY 641
H C G C C G+ SC R +HC I C NGG+C
Sbjct: 87 HSCGDGFCSRPNMCTCPSGQIAPSCGSRSI-QHCNIR---------CMNGGSC----SDD 132
Query: 642 KCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPP 701
C C G+ G HC P S C+NGG C + C C G+ G +C+ + GP
Sbjct: 133 HCLCQKGYIGTHCG---QPVCESGCLNGGRCVAPNR---CACTYGFTGPQCERDYRTGPC 186
Query: 702 EEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP 761
T+ N G ++ C + + R W P E+ + P
Sbjct: 187 -----FTVISNQMCQGQLSGIVCTKTLCCATVGR--------AWGHP---CEMCPAQPHP 230
Query: 762 CLHG-------GSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP--CRNGGSCRNLPGA 812
C G G+CQD DEC+A P C+ GG+C N G+
Sbjct: 231 CRRGFIPNIRTGACQDV---------------------DECQAIPGLCQ-GGNCINTVGS 268
Query: 813 YVCRCPAGF----VGVHCETEVDACDSSP--CQHGGRCESGGGAYLCVCPESFFGYHCET 866
+ C+CPAG V CE ++D C + P C+ GG C + +Y C CP F
Sbjct: 269 FECKCPAGHKLNEVSQKCE-DIDECSTIPGICE-GGECTNTVSSYFCKCPPGF------- 319
Query: 867 VSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTALKMERVEESGVSISW 926
++SP G R C+ + C T C+ +L P + KM+ ++G W
Sbjct: 320 -----YTSPDGTR--CIDVRPGY---CYTALTNGRCSNQL-PQSITKMQCCCDAG--RCW 366
Query: 927 NP 928
+P
Sbjct: 367 SP 368
Score = 58.9 bits (141), Expect = 3e-08
Identities = 40/126 (31%), Positives = 54/126 (42%), Gaps = 22/126 (17%)
Query: 268 TTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGR----RCHLDVNECASQPCQNG 323
T S C + C +C C Y CSC G+ +C +D NEC S G
Sbjct: 2561 TGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQC-VDENECLSAHICGG 2619
Query: 324 GTCTHGINSFRCQCPAGF------GG----PTCETAQSPCDTKECQHGGQCQVENGSAVC 373
+C + + S++C CPAGF GG C +AQ+P C +G C G +C
Sbjct: 2620 ASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAP-----CSYG--CSNTEGGYLC 2672
Query: 374 VCQAGY 379
C GY
Sbjct: 2673 GCPPGY 2678
Score = 31.6 bits (70), Expect = 5.6
Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
C +NPC GG C+ +++C C G++ C
Sbjct: 494 CEKNPCA-GGECINNQGSYTCQCRAGYQSTLTRTEC 528
Score = 31.6 bits (70), Expect = 5.6
Identities = 11/29 (37%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
Query: 1311 CSENP-CQNGGTCVPGADAHSCDCGPGFK 1338
C P CQ C+ A ++ CDC PG++
Sbjct: 1812 CQNGPVCQRNAECINTAGSYRCDCKPGYR 1840
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 191 bits (484), Expect = 6e-48
Identities = 146/466 (31%), Positives = 192/466 (41%), Gaps = 98/466 (21%)
Query: 257 DAQVRVGGCGHTTSVCLALRPCLNGGKCIDD--CVTGNPSYTCSCLSGFTGRRCHLDVNE 314
DA+ RV T V + CLNGG C+ D G+ Y C CL GF G C +D++
Sbjct: 1167 DAETRV-----TIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISG 1221
Query: 315 CASQPCQNGGTCTHGINSFRCQCPAGFGGPTC----------------ETAQSPCDTKEC 358
C S PC G + G +S+ C CP T ++ D K
Sbjct: 1222 CQSNPCGLGSYIS-GFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNA 1280
Query: 359 QHGGQCQVE--NGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP 416
Q G + V+ +G+A +C+ PC CV C C
Sbjct: 1281 Q-GRKRHVKPTSGNAFTICKY-----------------PCGKSRECV---APNICKCKPG 1319
Query: 417 FKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE--C 474
+ G C+T A C N G C+ + +C+C G G C E + C C
Sbjct: 1320 YIGSNCQT-------ALCDPDCKNHGKCIKPN---ICQCLPGHGGATCDE---EHCNPPC 1366
Query: 475 RNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTD 534
++GG CL N LC CP GF G CE M CN + C +GG C+ +C C
Sbjct: 1367 QHGGTCLAGN--LCTCPYGFVGPRCE----TMVCNRH--CENGGQCLTPD---ICQCKPG 1415
Query: 535 HNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGT 594
+ CD C NGGSC+ + TC CP GF G+HC+ A H PC+NGG
Sbjct: 1416 WYGPTCSTALCD-PVCLNGGSCNKPN---TCLCPNGFFGEHCQNAFCH----PPCKNGGH 1467
Query: 595 CKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHC 654
C C C +TGR + S C NGG C +G C CP G+SG+ C
Sbjct: 1468 CMR---NNVCVCREGYTGRRFQ----KSICDPTCMNGGKC---VGPSTCSCPSGWSGKRC 1517
Query: 655 EIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGP 700
+P C NGG C CHC + + G RCQ + C P
Sbjct: 1518 N---TPICLQKCKNGGEC---IAPSICHCPSSWEGVRCQIPI-CNP 1556
Score = 162 bits (411), Expect = 2e-39
Identities = 113/321 (35%), Positives = 145/321 (45%), Gaps = 52/321 (16%)
Query: 335 CQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPD 394
C+C G+ G C+TA CD +C++ G+C N +C C G+ GA C D + C+P
Sbjct: 1314 CKCKPGYIGSNCQTAL--CD-PDCKNHGKCIKPN---ICQCLPGHGGATC--DEEHCNP- 1364
Query: 395 PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCE 454
PC +GG+C L GN C C F G RCET + C NGG C+ D +C+
Sbjct: 1365 PCQHGGTC--LAGN-LCTCPYGFVGPRCET-------MVCNRHCENGGQCLTPD---ICQ 1411
Query: 455 CPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQC 514
C G+ G C + D C NGG C NT C CP GFFG C+ PC
Sbjct: 1412 CKPGWYGPTCSTALCDPV-CLNGGSCNKPNT--CLCPNGFFGEHCQNAFCHPPCK----- 1463
Query: 515 PDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGK 574
+GG+CM + +CVC + S CD C NGG C TC CP G+ GK
Sbjct: 1464 -NGGHCMRNN---VCVCREGYTGRRFQKSICD-PTCMNGGKCVGPS---TCSCPSGWSGK 1515
Query: 575 HCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTC 634
C +C C+NGG C C CP + G C+I + C GG C
Sbjct: 1516 RCNTP---ICLQ-KCKNGGECIAPS---ICHCPSSWEGVRCQI----PICNPKCLYGGRC 1564
Query: 635 FHYIGKYKCDCPPGFSGRHCE 655
I C C +SG CE
Sbjct: 1565 ---IFPNVCSCRTEYSGVKCE 1582
Score = 149 bits (376), Expect = 2e-35
Identities = 106/316 (33%), Positives = 137/316 (43%), Gaps = 51/316 (16%)
Query: 263 GGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQN 322
G G L C N GKCI + C CL G G C D C + PCQ+
Sbjct: 1319 GYIGSNCQTALCDPDCKNHGKCIKPNI-------CQCLPGHGGATC--DEEHC-NPPCQH 1368
Query: 323 GGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGA 382
GGTC G C CP GF GP CET + C++GGQC + +C C+ G+ G
Sbjct: 1369 GGTCLAGN---LCTCPYGFVGPRCETMVC---NRHCENGGQCLTPD---ICQCKPGWYGP 1419
Query: 383 ACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG 442
C + C P CLNGGSC TCLC F G C+ +A PC NGG
Sbjct: 1420 TCSTAL--CDP-VCLNGGSCNK---PNTCLCPNGFFGEHCQ-------NAFCHPPCKNGG 1466
Query: 443 TCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFE 502
C+ + VC C EG+ G ++ + D C NGG+C+G +T C CP G+ G C
Sbjct: 1467 HCM---RNNVCVCREGYTGRRFQKSICDP-TCMNGGKCVGPST--CSCPSGWSGKRCNTP 1520
Query: 503 ITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDS 562
I +C +GG C+ +C C + P + C GG C +
Sbjct: 1521 ICLQ------KCKNGGECI---APSICHCPSSWEGVR-CQIPICNPKCLYGGRCIFPN-- 1568
Query: 563 YTCECPRGFHGKHCEK 578
C C + G CEK
Sbjct: 1569 -VCSCRTEYSGVKCEK 1583
Score = 139 bits (350), Expect = 2e-32
Identities = 134/482 (27%), Positives = 186/482 (38%), Gaps = 124/482 (25%)
Query: 472 CECRNGGRCL-------GANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHG 524
C+C NGG C+ G+ LC C GF G LCE +I+ N C G Y +
Sbjct: 1181 CDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSN---PCGLGSY-ISGF 1236
Query: 525 GSYLCVC-------------------------------HTDHNAS----HSLPSPCDSD- 548
SY C C D NA H P+ ++
Sbjct: 1237 HSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFT 1296
Query: 549 ----PCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHC 604
PC C A + C+C G+ G +C+ A LC C+N G C + C
Sbjct: 1297 ICKYPCGKSRECVAPN---ICKCKPGYIGSNCQTA---LCDPD-CKNHGKCIKPN---IC 1346
Query: 605 SCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRS 664
C G C+ + + PC +GGTC + C CP GF G CE C R
Sbjct: 1347 QCLPGHGGATCD----EEHCNPPCQHGGTC---LAGNLCTCPYGFVGPRCETMV--CNRH 1397
Query: 665 PCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYAC 724
C NGG C D C C+ G+ G C + C P C
Sbjct: 1398 -CENGGQCLTPD---ICQCKPGWYGPTCSTAL-CDP----------------------VC 1430
Query: 725 DRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE 784
G S + P+ +C P+G + E Q + PC +GG C + +C+C GY
Sbjct: 1431 LNGGSCNKPNTC-LC-PNGFFGEHCQ----NAFCHPPCKNGGHC---MRNNVCVCREGYT 1481
Query: 785 GAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRC 844
G ++ C C NGG C G C CP+G+ G C T + C C++GG C
Sbjct: 1482 GRR--FQKSICDP-TCMNGGKC---VGPSTCSCPSGWSGKRCNTPI--C-LQKCKNGGEC 1532
Query: 845 ESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAK 904
+ +C CP S+ G C+ P + C G C+ N C+C+ Y+G C K
Sbjct: 1533 IAPS---ICHCPSSWEGVRCQI---PICNPKCLYGGRCIFPN---VCSCRTEYSGVKCEK 1583
Query: 905 EL 906
++
Sbjct: 1584 KI 1585
Score = 114 bits (284), Expect = 9e-25
Identities = 94/335 (28%), Positives = 134/335 (40%), Gaps = 72/335 (21%)
Query: 628 CHNGGTCFHY------IGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFC 681
C NGG+C G Y C C PGF G CE+ S C +PC G + + C
Sbjct: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHS-YSC 1241
Query: 682 HC------QAGYMGR-------RCQAEVDCGPPEEVKHATLRFNGTR-----LGAVALYA 723
C + ++ + +++ E+ K+A R + + Y
Sbjct: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
Query: 724 CDRGYSLSAPSRIRV-----------------CQPHGVWSEPP--QCLE-------IDEC 757
C + AP+ + C+ HG +P QCL +E
Sbjct: 1302 CGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEH 1361
Query: 758 RSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRC 817
+ PC HGG+C +AG LC C G+ G CE C H C NGG C +C+C
Sbjct: 1362 CNPPCQHGGTC---LAGNLCTCPYGFVGPRCETM--VCNRH-CENGGQCLT---PDICQC 1412
Query: 818 PAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCG 877
G+ G C T + CD C +GG C C+CP FFG HC+ + PC
Sbjct: 1413 KPGWYGPTCSTAL--CD-PVCLNGGSCNKPN---TCLCPNGFFGEHCQ---NAFCHPPCK 1463
Query: 878 GRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTAL 912
G+C+ +N C C+ GYTG K + PT +
Sbjct: 1464 NGGHCMRNN---VCVCREGYTGRRFQKSICDPTCM 1495
Score = 95.1 bits (235), Expect = 4e-19
Identities = 65/213 (30%), Positives = 94/213 (44%), Gaps = 35/213 (16%)
Query: 256 DDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNEC 315
D Q + G G T S L CLNGG C N TC C +GF G C N
Sbjct: 1408 DICQCKPGWYGPTCSTALCDPVCLNGGSC-------NKPNTCLCPNGFFGEHCQ---NAF 1457
Query: 316 ASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVC 375
PC+NGG C + + C C G+ G + +S CD C +GG+C G + C C
Sbjct: 1458 CHPPCKNGGHC---MRNNVCVCREGYTGRRFQ--KSICD-PTCMNGGKCV---GPSTCSC 1508
Query: 376 QAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLS 435
+G++G C + C NGG C + C C ++G+RC+ +P +
Sbjct: 1509 PSGWSGKRCNTPI---CLQKCKNGGEC---IAPSICHCPSSWEGVRCQ-----IP--ICN 1555
Query: 436 APCHNGGTCVDADQGYVCECPEGFMGLDCRERV 468
C GG C+ + VC C + G+ C +++
Sbjct: 1556 PKCLYGGRCIFPN---VCSCRTEYSGVKCEKKI 1585
Score = 55.5 bits (132), Expect = 4e-07
Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 20/163 (12%)
Query: 758 RSQPCLHGGSC-QDRVAG-----YLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPG 811
+S CL+GGSC DR YLC+C G+ G+ CE++ C+++PC G
Sbjct: 1179 KSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGF-H 1237
Query: 812 AYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFG--YHCETVSD 869
+Y C CP + E + Q S ++ G H + S
Sbjct: 1238 SYSCDCPP-----ELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSG 1292
Query: 870 PCFS---SPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPP 909
F+ PCG C+A N C CK GY G +C L P
Sbjct: 1293 NAFTICKYPCGKSRECVAPN---ICKCKPGYIGSNCQTALCDP 1332
Score = 52.8 bits (125), Expect = 2e-06
Identities = 35/89 (39%), Positives = 40/89 (44%), Gaps = 19/89 (21%)
Query: 824 VHCETEVDACDSSPCQHGGRCES------GGGAYLCVCPESFFGYHCETVSDPCFSSPCG 877
V E V +CD C +GG C S G G YLCVC F G CE C S+PCG
Sbjct: 1172 VTIEVTVKSCD---CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCG 1228
Query: 878 GRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Y +G HS +C DC EL
Sbjct: 1229 LGSYI---SGFHSYSC-------DCPPEL 1247
Score = 38.5 bits (88), Expect = 0.046
Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 14/52 (26%)
Query: 1296 LPEHGSKDIGNVPGNCSEN----PCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
LP HG C E PCQ+GGTC+ G + C C GF G RCE
Sbjct: 1349 LPGHGG-------ATCDEEHCNPPCQHGGTCLAG---NLCTCPYGFVGPRCE 1390
Score = 36.2 bits (82), Expect = 0.23
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 6/35 (17%)
Query: 1316 CQNGGTCV------PGADAHSCDCGPGFKGRRCEL 1344
C NGG+CV PG+ + C C PGF G CE+
Sbjct: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEV 1217
Score = 31.2 bits (69), Expect = 7.4
Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query: 1290 VSLALQLPE-HGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFK 1338
V L + LP HGS ++ G C NPC G+ + G ++SCDC P K
Sbjct: 1201 VYLCVCLPGFHGSLCEVDISG-CQSNPC-GLGSYISGFHSYSCDCPPELK 1248
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 171 bits (433), Expect = 5e-42
Identities = 88/251 (35%), Positives = 121/251 (48%), Gaps = 25/251 (9%)
Query: 270 SVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTC--- 326
+ CL+ PC N G C D V Y C+C + G+ C + +N C PCQ+GGTC
Sbjct: 918 NACLS-SPCKNNGTCTQDPVE---LYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLS 973
Query: 327 -THGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACE 385
+H + F C CP GF G CE C+ +C++ C + VC+C YTG C+
Sbjct: 974 DSHK-DGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCD 1032
Query: 386 MDVDDCSPDP--CLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGT 443
+D C P+ C + C+ L ++C C + G CET + D C++ C +G
Sbjct: 1033 EVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDN----DDCVAHKCRHGAQ 1088
Query: 444 CVDADQGYVCECPEGFMGLDCRERVP---------DDCECRNGGRCLGA-NTTLCQCPLG 493
CVD GY C CP+GF G C P D EC+NG +C+ C+CP G
Sbjct: 1089 CVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPG 1148
Query: 494 FFGLLCEFEIT 504
F G CE IT
Sbjct: 1149 FAGPRCEKLIT 1159
Score = 169 bits (428), Expect = 2e-41
Identities = 95/275 (34%), Positives = 123/275 (44%), Gaps = 45/275 (16%)
Query: 313 NECASQPCQNGGTCTHG-INSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSA 371
N C S PC+N GTCT + +RC CP + G C + C CQHGG C + +
Sbjct: 918 NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHK 977
Query: 372 ---VCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRC-ETGDH 427
C C G+ G CE++ DDC + C N +CVD + NY C+C + G C E DH
Sbjct: 978 DGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDH 1037
Query: 428 PVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGA- 483
VP+ L C + C+ D+G+ CEC G+ G C E DDC +CR+G +C+
Sbjct: 1038 CVPELNL---CQHEAKCIPLDKGFSCECVPGYSGKLC-ETDNDDCVAHKCRHGAQCVDTI 1093
Query: 484 NTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS 543
N C CP GF G +C EH + + S
Sbjct: 1094 NGYTCTCPQGF---------------------SGPFC-EHPPPMVLL----------QTS 1121
Query: 544 PCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEK 578
PCD C NG C TC CP GF G CEK
Sbjct: 1122 PCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEK 1156
Score = 157 bits (397), Expect = 7e-38
Identities = 86/261 (32%), Positives = 118/261 (45%), Gaps = 32/261 (12%)
Query: 579 ARPHLCSSGPCRNGGTCKEAGGE-YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCF-- 635
A+ + C S PC+N GTC + E Y C+CPY + G+ C + ++C PC +GGTC
Sbjct: 915 AKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV-PINTCIQNPCQHGGTCHLS 973
Query: 636 --HYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQ 693
H G + C CP GF G+ CEI P C + C N TC D ++ C C Y G C
Sbjct: 974 DSHKDG-FSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCD 1032
Query: 694 AEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLE 753
+D H N + A + D+G+S C+ +S +
Sbjct: 1033 EVID--------HCVPELNLCQHEAKCI-PLDKGFS---------CECVPGYSGKLCETD 1074
Query: 754 IDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE-------LERDECRAHPCRNGGSC 806
D+C + C HG C D + GY C C G+ G CE L+ C + C+NG C
Sbjct: 1075 NDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQC 1134
Query: 807 RNLPGAYVCRCPAGFVGVHCE 827
+ CRCP GF G CE
Sbjct: 1135 IVVQQEPTCRCPPGFAGPRCE 1155
Score = 151 bits (382), Expect = 4e-36
Identities = 74/213 (34%), Positives = 101/213 (47%), Gaps = 15/213 (7%)
Query: 265 CGHTTSVCLALRPCLNGGKC-IDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNG 323
C + C+ PC +GG C + D + ++CSC GF G+RC ++ ++C C+N
Sbjct: 952 CTVPINTCIQ-NPCQHGGTCHLSD--SHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENN 1008
Query: 324 GTCTHGINSFRCQCPAGFGGPTCETAQSPC--DTKECQHGGQCQVENGSAVCVCQAGYTG 381
TC GIN++ C CP + G C+ C + CQH +C + C C GY+G
Sbjct: 1009 ATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSG 1068
Query: 382 AACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVP------DACLS 435
CE D DDC C +G CVD + YTC C + F G CE HP P C
Sbjct: 1069 KLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE---HPPPMVLLQTSPCDQ 1125
Query: 436 APCHNGGTCVDADQGYVCECPEGFMGLDCRERV 468
C NG C+ Q C CP GF G C + +
Sbjct: 1126 YECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLI 1158
Score = 148 bits (374), Expect = 3e-35
Identities = 83/263 (31%), Positives = 115/263 (43%), Gaps = 35/263 (13%)
Query: 617 IGKPDSCASGPCHNGGTCFHY-IGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDR 675
+ K ++C S PC N GTC + Y+C CP + G+ C + + C ++PC +GGTC
Sbjct: 914 VAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLS 973
Query: 676 DTD---FFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSA 732
D+ F C C G+ G+RC+ P++ + N T + + Y C
Sbjct: 974 DSHKDGFSCSCPLGFEGQRCEIN-----PDDCEDNDCENNATCVDGINNYVC-------- 1020
Query: 733 PSRIRVCQPHGVWSEPPQCLE-IDECRSQP--CLHGGSCQDRVAGYLCLCSTGYEGAHCE 789
+C P+ C E ID C + C H C G+ C C GY G CE
Sbjct: 1021 -----ICPPNYTGE---LCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCE 1072
Query: 790 LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCE-------TEVDACDSSPCQHGG 842
+ D+C AH CR+G C + Y C CP GF G CE + CD CQ+G
Sbjct: 1073 TDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGA 1132
Query: 843 RCESGGGAYLCVCPESFFGYHCE 865
+C C CP F G CE
Sbjct: 1133 QCIVVQQEPTCRCPPGFAGPRCE 1155
Score = 136 bits (343), Expect = 1e-31
Identities = 80/245 (32%), Positives = 113/245 (46%), Gaps = 27/245 (11%)
Query: 431 DACLSAPCHNGGTCV-DADQGYVCECPEGFMGLDCRERVPDDCE--CRNGGRCLGANTTL 487
+ACLS+PC N GTC D + Y C CP + G DC + + C++GG C +++
Sbjct: 918 NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHK 977
Query: 488 ----CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNAS----- 538
C CPLGF G CE I C N C + C++ +Y+C+C ++
Sbjct: 978 DGFSCSCPLGFEGQRCE--INPDDCEDN-DCENNATCVDGINNYVCICPPNYTGELCDEV 1034
Query: 539 --HSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCK 596
H +P + + C + C D ++CEC G+ GK CE C + CR+G C
Sbjct: 1035 IDHCVP---ELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDD-CVAHKCRHGAQCV 1090
Query: 597 EAGGEYHCSCPYRFTGRHCEIGKP------DSCASGPCHNGGTCFHYIGKYKCDCPPGFS 650
+ Y C+CP F+G CE P C C NG C + C CPPGF+
Sbjct: 1091 DTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFA 1150
Query: 651 GRHCE 655
G CE
Sbjct: 1151 GPRCE 1155
Score = 132 bits (333), Expect = 2e-30
Identities = 82/242 (33%), Positives = 106/242 (43%), Gaps = 22/242 (9%)
Query: 391 CSPDPCLNGGSCV-DLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQ 449
C PC N G+C D V Y C C +KG C P+ + C+ PC +GGTC +D
Sbjct: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV---PI-NTCIQNPCQHGGTCHLSDS 975
Query: 450 ---GYVCECPEGFMGLDCRERVPDDCE---CRNGGRCL-GANTTLCQCPLGFFGLLCEFE 502
G+ C CP GF G C E PDDCE C N C+ G N +C CP + G LC+
Sbjct: 976 HKDGFSCSCPLGFEGQRC-EINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEV 1034
Query: 503 ITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNAS--HSLPSPCDSDPCFNGGSCDAHD 560
I +N C C+ + C C ++ + C + C +G C
Sbjct: 1035 IDHCVPELNL-CQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTI 1093
Query: 561 DSYTCECPRGFHGKHCEKARPHL------CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRH 614
+ YTC CP+GF G CE P + C C+NG C E C CP F G
Sbjct: 1094 NGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPR 1153
Query: 615 CE 616
CE
Sbjct: 1154 CE 1155
Score = 115 bits (289), Expect = 2e-25
Identities = 69/258 (26%), Positives = 97/258 (37%), Gaps = 66/258 (25%)
Query: 661 CFRSPCVNGGTCEDRDTDFF-CHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAV 719
C SPC N GTC + + C C Y G+ DC P
Sbjct: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGK------DCTVP------------------ 955
Query: 720 ALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQ---DRVAGYL 776
I+ C PC HGG+C G+
Sbjct: 956 ----------------------------------INTCIQNPCQHGGTCHLSDSHKDGFS 981
Query: 777 CLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDAC--D 834
C C G+EG CE+ D+C + C N +C + YVC CP + G C+ +D C +
Sbjct: 982 CSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPE 1041
Query: 835 SSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCK 894
+ CQH +C + C C + G CET +D C + C C+ + ++CTC
Sbjct: 1042 LNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCP 1101
Query: 895 VGYTGEDCAKELFPPTAL 912
G++G C E PP L
Sbjct: 1102 QGFSGPFC--EHPPPMVL 1117
Score = 73.2 bits (178), Expect = 2e-12
Identities = 48/146 (32%), Positives = 69/146 (47%), Gaps = 18/146 (12%)
Query: 330 INSFRCQCPAGFG-GPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDV 388
+ F+ P G P C++ C+HG VE S VC C+ G+TG C+ +
Sbjct: 1315 LQDFKALPPQSLGVSPGCKSCTV------CKHGLCRSVEKDSVVCECRPGWTGPLCDQE- 1367
Query: 389 DDCSPDPCL----NGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
+ DPCL + G CV +Y C CAE + G C+ + +AC + CH+ G C
Sbjct: 1368 ---ARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSA-NACSAFKCHH-GQC 1422
Query: 445 VDADQGY-VCECPEGFMGLDCRERVP 469
+DQG C C GF G C++ P
Sbjct: 1423 HISDQGEPYCLCQPGFSGEHCQQENP 1448
Score = 67.8 bits (164), Expect = 7e-11
Identities = 43/145 (29%), Positives = 64/145 (44%), Gaps = 20/145 (13%)
Query: 294 SYTCSCLSGFTGRRCHLDVNE-CASQPCQNGGTCTHGINSFRCQCPAGFGGPTCET---A 349
S C C G+TG C + + C C + G C S+ C+C G+GG C+ +
Sbjct: 1350 SVVCECRPGWTGPLCDQEARDPCLGHRCHH-GKCVATGTSYMCKCAEGYGGDLCDNKNDS 1408
Query: 350 QSPCDTKECQHGGQCQV-ENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLV-- 406
+ C +C H GQC + + G C+CQ G++G C+ + +PCL G V V
Sbjct: 1409 ANACSAFKCHH-GQCHISDQGEPYCLCQPGFSGEHCQQE------NPCL--GQVVREVIR 1459
Query: 407 ---GNYTCLCAEPFKGLRCETGDHP 428
G +C A + C G P
Sbjct: 1460 RQKGYASCATASKVPIMECRGGCGP 1484
Score = 66.6 bits (161), Expect = 2e-10
Identities = 39/115 (33%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Query: 550 CFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYR 609
C +G DS CEC G+ G C++ C C +G C G Y C C
Sbjct: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEG 1396
Query: 610 FTGRHCEIGKPDS---CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPC 661
+ G C+ K DS C++ CH+G G+ C C PGFSG HC+ +PC
Sbjct: 1397 YGGDLCD-NKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ-QENPC 1449
Score = 64.7 bits (156), Expect = 6e-10
Identities = 38/117 (32%), Positives = 52/117 (44%), Gaps = 11/117 (9%)
Query: 317 SQPCQNGGTCTHGI------NSFRCQCPAGFGGPTC-ETAQSPCDTKECQHGGQCQVENG 369
S C++ C HG+ +S C+C G+ GP C + A+ PC C H G+C
Sbjct: 1329 SPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHH-GKCVATGT 1387
Query: 370 SAVCVCQAGYTGAACEMDVDD---CSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCE 423
S +C C GY G C+ D CS C +G + G CLC F G C+
Sbjct: 1388 SYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
Score = 64.7 bits (156), Expect = 6e-10
Identities = 37/117 (31%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 795 CRAHPCRNGGSCRNLP-GAYVCRCPAGFVGVHCETEV-DACDSSPCQHGGRCESGGGAYL 852
C++ G CR++ + VC C G+ G C+ E D C C HG +C + G +Y+
Sbjct: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYM 1390
Query: 853 CVCPESFFGYHCETVSD---PCFSSPCGGRGYC-LASNGSHSCTCKVGYTGEDCAKE 905
C C E + G C+ +D C + C G C ++ G C C+ G++GE C +E
Sbjct: 1391 CKCAEGYGGDLCDNKNDSANACSAFKC-HHGQCHISDQGEPYCLCQPGFSGEHCQQE 1446
Score = 59.3 bits (142), Expect = 3e-08
Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 820 GFVGVHCETEVDACDSSPCQHGGRC-ESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGG 878
G V ++ + +AC SSPC++ G C + Y C CP S+ G C + C +PC
Sbjct: 907 GPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQH 966
Query: 879 RGYCLASNG---SHSCTCKVGYTGEDC 902
G C S+ SC+C +G+ G+ C
Sbjct: 967 GGTCHLSDSHKDGFSCSCPLGFEGQRC 993
Score = 57.8 bits (138), Expect = 7e-08
Identities = 37/121 (30%), Positives = 47/121 (38%), Gaps = 5/121 (4%)
Query: 713 GTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEI-DECRSQPCLHGGSCQDR 771
G G + C G S VC+ W+ P E D C C H G C
Sbjct: 1327 GVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRC-HHGKCVAT 1385
Query: 772 VAGYLCLCSTGYEGAHCELERDE---CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCET 828
Y+C C+ GY G C+ + D C A C +G + G C C GF G HC+
Sbjct: 1386 GTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQ 1445
Query: 829 E 829
E
Sbjct: 1446 E 1446
Score = 52.8 bits (125), Expect = 2e-06
Identities = 33/119 (27%), Positives = 46/119 (38%), Gaps = 5/119 (4%)
Query: 584 CSSGPCRNGGTCKEAGGE-YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYK 642
C S G C+ + C C +TG C+ D C CH+G C Y
Sbjct: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYM 1390
Query: 643 CDCPPGFSGRHCEI---APSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDC 698
C C G+ G C+ + + C C +G + +C CQ G+ G CQ E C
Sbjct: 1391 CKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPC 1449
Score = 50.1 bits (118), Expect = 2e-05
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 9/116 (7%)
Query: 474 CRNG-GRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCH 532
C++G R + ++ +C+C G+ G LC+ E PC + +C G C+ G SY+C C
Sbjct: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARD-PC-LGHRCHHGK-CVATGTSYMCKCA 1394
Query: 533 TDHNAS-----HSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHL 583
+ + + C + C +G + C C GF G+HC++ P L
Sbjct: 1395 EGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCL 1450
Score = 47.0 bits (110), Expect = 1e-04
Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 7/123 (5%)
Query: 429 VPDACLSAPCHNGGTCVDADQ-GYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGAN 484
V C S G C ++ VCEC G+ G C + D C C + G+C+
Sbjct: 1328 VSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHH-GKCVATG 1386
Query: 485 TT-LCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASH-SLP 542
T+ +C+C G+ G LC+ + + +C G + G C+C + H
Sbjct: 1387 TSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE 1446
Query: 543 SPC 545
+PC
Sbjct: 1447 NPC 1449
Score = 45.4 bits (106), Expect = 4e-04
Identities = 22/42 (52%), Positives = 27/42 (64%), Gaps = 4/42 (9%)
Query: 1307 VPGN-CSENPCQNGGTC---VPGADAHSCDCGPGFKGRRCEL 1344
VP N C +NPCQ+GGTC D SC C GF+G+RCE+
Sbjct: 954 VPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEI 995
Score = 45.4 bits (106), Expect = 4e-04
Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 9/90 (10%)
Query: 1308 PGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELA---CIKVSRPCTRLFSETKAFP 1364
P +C +N C+N TCV G + + C C P + G C+ C+ C E K P
Sbjct: 997 PDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQH---EAKCIP 1053
Query: 1365 VWEGGVCHHV---YKRVYRVHQDICFKESC 1391
+ +G C V ++ D C C
Sbjct: 1054 LDKGFSCECVPGYSGKLCETDNDDCVAHKC 1083
Score = 43.1 bits (100), Expect = 0.002
Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
Query: 277 PCLNGGKCIDD-CVTGNPSYTCSCLSGFTGRRC---HLDVNECASQPCQNGGTCTHGINS 332
PCL G +C CV SY C C G+ G C + N C++ C +G
Sbjct: 1371 PCL-GHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGE 1429
Query: 333 FRCQCPAGFGGPTCETAQSPC 353
C C GF G C+ ++PC
Sbjct: 1430 PYCLCQPGFSGEHCQ-QENPC 1449
Score = 40.0 bits (92), Expect = 0.016
Identities = 15/33 (45%), Positives = 18/33 (54%)
Query: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
C + CQNG C+ +C C PGF G RCE
Sbjct: 1123 CDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
Score = 36.6 bits (83), Expect = 0.18
Identities = 28/97 (28%), Positives = 37/97 (38%), Gaps = 25/97 (25%)
Query: 1287 PKRVSLALQLPEHGSKDIGNVPGN-------CSENPCQNGGTCVPG-ADAHSCDCGPGFK 1338
P L L P H + G V N C +PC+N GTC + + C C +K
Sbjct: 889 PMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYK 948
Query: 1339 GRRCEL---ACIKVSRPCTRLFSETKAFPVWEGGVCH 1372
G+ C + CI+ PC GG CH
Sbjct: 949 GKDCTVPINTCIQ--NPCQ------------HGGTCH 971
Score = 34.3 bits (77), Expect = 0.87
Identities = 12/34 (35%), Positives = 19/34 (55%)
Query: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
+C + C++G CV + ++C C GF G CE
Sbjct: 1077 DCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,757,185
Number of Sequences: 37866
Number of extensions: 3928996
Number of successful extensions: 29310
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 220
Number of HSP's successfully gapped in prelim test: 381
Number of HSP's that attempted gapping in prelim test: 8616
Number of HSP's gapped (non-prelim): 7746
length of query: 1413
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1298
effective length of database: 13,892,928
effective search space: 18033020544
effective search space used: 18033020544
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.