Guide to the Human Genome
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Search of human proteins with 28269707

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28269707 C-type lectin domain family 14, member A [Homo
sapiens]
         (490 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28269707 C-type lectin domain family 14, member A [Homo sapiens]  1008   0.0  
gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens]        127   2e-29
gi|88758613 CD93 antigen precursor [Homo sapiens]                      96   6e-20
gi|4507483 thrombomodulin precursor [Homo sapiens]                     75   1e-13
gi|20127636 chondrolectin precursor [Homo sapiens]                     51   2e-06
gi|190343004 EGF-containing fibulin-like extracellular matrix pr...    44   4e-04
gi|28558982 thyroid peroxidase isoform a [Homo sapiens]                42   0.001
gi|28558984 thyroid peroxidase isoform b [Homo sapiens]                42   0.001
gi|28558990 thyroid peroxidase isoform e [Homo sapiens]                42   0.001
gi|126012573 low density lipoprotein-related protein 2 [Homo sap...    42   0.001
gi|22547221 tolloid-like 1 [Homo sapiens]                              42   0.002
gi|56237021 fibrillin 3 precursor [Homo sapiens]                       41   0.002
gi|24430141 fibrillin 1 precursor [Homo sapiens]                       40   0.006
gi|86788132 EGF-containing fibulin-like extracellular matrix pro...    40   0.006
gi|86788015 EGF-containing fibulin-like extracellular matrix pro...    40   0.006
gi|9665262 EGF-containing fibulin-like extracellular matrix prot...    40   0.006
gi|66346695 fibrillin 2 precursor [Homo sapiens]                       39   0.008
gi|21264602 laminin alpha 5 [Homo sapiens]                             39   0.014
gi|19743803 fibulin 5 precursor [Homo sapiens]                         38   0.024
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]                38   0.024
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]     37   0.031
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]    37   0.031
gi|157384998 low density lipoprotein receptor-related protein 4 ...    37   0.041
gi|192447438 protein S, alpha preproprotein [Homo sapiens]             37   0.053
gi|4506115 protein C [Homo sapiens]                                    37   0.053
gi|4557733 latent transforming growth factor beta binding protei...    37   0.053
gi|46249414 latent transforming growth factor beta binding prote...    36   0.070
gi|46249412 latent transforming growth factor beta binding prote...    36   0.070
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              36   0.070
gi|187829730 BCL2 binding component 3 isoform 1 [Homo sapiens]         36   0.070

>gi|28269707 C-type lectin domain family 14, member A [Homo sapiens]
          Length = 490

 Score = 1008 bits (2605), Expect = 0.0
 Identities = 490/490 (100%), Positives = 490/490 (100%)

Query: 1   MRPAFALCLLWQALWPGPGGGEHPTADRAGCSASGACYSLHHATMKRQAAEEACILRGGA 60
           MRPAFALCLLWQALWPGPGGGEHPTADRAGCSASGACYSLHHATMKRQAAEEACILRGGA
Sbjct: 1   MRPAFALCLLWQALWPGPGGGEHPTADRAGCSASGACYSLHHATMKRQAAEEACILRGGA 60

Query: 61  LSTVRAGAELRAVLALLRAGPGPGGGSKDLLFWVALERRRSHCTLENEPLRGFSWLSSDP 120
           LSTVRAGAELRAVLALLRAGPGPGGGSKDLLFWVALERRRSHCTLENEPLRGFSWLSSDP
Sbjct: 61  LSTVRAGAELRAVLALLRAGPGPGGGSKDLLFWVALERRRSHCTLENEPLRGFSWLSSDP 120

Query: 121 GGLESDTLQWVEEPQRSCTARRCAVLQATGGVEPAGWKEMRCHLRANGYLCKYQFEVLCP 180
           GGLESDTLQWVEEPQRSCTARRCAVLQATGGVEPAGWKEMRCHLRANGYLCKYQFEVLCP
Sbjct: 121 GGLESDTLQWVEEPQRSCTARRCAVLQATGGVEPAGWKEMRCHLRANGYLCKYQFEVLCP 180

Query: 181 APRPGAASNLSYRAPFQLHSAALDFSPPGTEVSALCRGQLPISVTCIADEIGARWDKLSG 240
           APRPGAASNLSYRAPFQLHSAALDFSPPGTEVSALCRGQLPISVTCIADEIGARWDKLSG
Sbjct: 181 APRPGAASNLSYRAPFQLHSAALDFSPPGTEVSALCRGQLPISVTCIADEIGARWDKLSG 240

Query: 241 DVLCPCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTG 300
           DVLCPCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTG
Sbjct: 241 DVLCPCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTG 300

Query: 301 VPTRRPPATATSPVPQRTWPIRVDEKLGETPLVPEQDNSVTSIPEIPRWGSQSTMSTLQM 360
           VPTRRPPATATSPVPQRTWPIRVDEKLGETPLVPEQDNSVTSIPEIPRWGSQSTMSTLQM
Sbjct: 301 VPTRRPPATATSPVPQRTWPIRVDEKLGETPLVPEQDNSVTSIPEIPRWGSQSTMSTLQM 360

Query: 361 SLQAESKATITPSGSVISKFNSTTSSATPQAFDSSSAVVFIFVSTAVVVLVILTMTVLGL 420
           SLQAESKATITPSGSVISKFNSTTSSATPQAFDSSSAVVFIFVSTAVVVLVILTMTVLGL
Sbjct: 361 SLQAESKATITPSGSVISKFNSTTSSATPQAFDSSSAVVFIFVSTAVVVLVILTMTVLGL 420

Query: 421 VKLCFHESPSSQPRKESMGPPGLESDPEPAALGSSSAHCTNNGVKVGDCDLRDRAEGALL 480
           VKLCFHESPSSQPRKESMGPPGLESDPEPAALGSSSAHCTNNGVKVGDCDLRDRAEGALL
Sbjct: 421 VKLCFHESPSSQPRKESMGPPGLESDPEPAALGSSSAHCTNNGVKVGDCDLRDRAEGALL 480

Query: 481 AESPLGSSDA 490
           AESPLGSSDA
Sbjct: 481 AESPLGSSDA 490


>gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens]
          Length = 757

 Score =  127 bits (320), Expect = 2e-29
 Identities = 93/285 (32%), Positives = 127/285 (44%), Gaps = 23/285 (8%)

Query: 7   LCLLWQALWPGPGGGEHPTADRAGCSASGACYSLHHATMKRQAAEEACILRGGALSTVRA 66
           L L W A  P  G        RA C  S +CY+L         A  AC   GG L+T R 
Sbjct: 5   LLLAWAAAGPTLGQDPWAAEPRAACGPS-SCYALFPRRRTFLEAWRACRELGGDLATPRT 63

Query: 67  GAELRAVLALLRAGPGPGGGSKDLLFWVALERRRSHCTLENEPLRGFSWLSSDPGGLESD 126
             E + V +L+ AGP         L W+ L+R+   C L+  PLRGF+W + D    ++ 
Sbjct: 64  PEEAQRVDSLVGAGPA------SRLLWIGLQRQARQCQLQR-PLRGFTWTTGDQ---DTA 113

Query: 127 TLQWVEEPQRS-CTARRCAVLQATGGVEPAGWKEMRCHLRANGYLCKYQFEVLCPA--PR 183
              W +      C A+RC  L+A+G      W E  C L  +GYLC++ FE  CPA    
Sbjct: 114 FTNWAQPASGGPCPAQRCVALEASGEHR---WLEGSCTLAVDGYLCQFGFEGACPALQDE 170

Query: 184 PGAASNLSYRAPFQLHSAALDFSPPGTEVSALCRGQLPISVTCIAD-EIGARWDKLSGDV 242
            G A    Y  PF L S   ++ P G+  +  C+     S+ C+   E G  W +     
Sbjct: 171 AGQAGPAVYTTPFHLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVGWSR--AGP 228

Query: 243 LCPCPGRYLRAGKCAELPNCLDDLGG-FACECATGFELGKDGRSC 286
           LC   G     G C     C++++ G  +C C  GF L  DGRSC
Sbjct: 229 LCLGTGCSPDNGGCEH--ECVEEVDGHVSCRCTEGFRLAADGRSC 271



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 17/38 (44%), Positives = 24/38 (63%), Gaps = 2/38 (5%)

Query: 253 AGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSG 290
           AG C ++  C++ +GGF C C+ G EL  DG SC  +G
Sbjct: 319 AGVCQQM--CVNYVGGFECYCSEGHELEADGISCSPAG 354


>gi|88758613 CD93 antigen precursor [Homo sapiens]
          Length = 652

 Score = 96.3 bits (238), Expect = 6e-20
 Identities = 85/323 (26%), Positives = 135/323 (41%), Gaps = 34/323 (10%)

Query: 1   MRPAFALCLLWQALWPGPGGGEHPTADRAGCSASGACYSLHHATMKRQAAEEACILRGGA 60
           M  +  L LL   L   PG G     +   C  + ACY+ H   +    A+  C   GG 
Sbjct: 1   MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGT-ACYTAHSGKLSAAEAQNHCNQNGGN 59

Query: 61  LSTVRAGAELRAVLALL-----RAGPGPGGGSKDLLFWVALERRRSHCTLENEPLRGFSW 115
           L+TV++  E + V  +L     R        SK   FW+ L+R +  C   + PL+GFSW
Sbjct: 60  LATVKSKEEAQHVQRVLAQLLRREAALTARMSK---FWIGLQREKGKCLDPSLPLKGFSW 116

Query: 116 LSSDPGGLESDTLQWVEEPQRSCTARRCA--VLQATGGVEPAG---WKEMRCHLRAN--- 167
           +    GG ++    W +E + SC ++RC   +L  +  + P+    W E  C    +   
Sbjct: 117 VG---GGEDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGS 173

Query: 168 ---GYLCKYQFEVLCPAPRPGAASNLSYRAPFQLHSAALDFSPPGTEVSALC----RGQL 220
              G++CK+ F+ +C     G    ++Y  PFQ  S++L+  P  +  +  C    + + 
Sbjct: 174 NIEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDET 233

Query: 221 PISVTCIADEIGARWDKLSGDVLCPCP--GRYLRAGKCAELPNCLD-DLGGFACECATGF 277
                   ++    +D  S   LC  P  G     G C +  +C +   G F C C  GF
Sbjct: 234 QSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQ--DCFEGGDGSFLCGCRPGF 291

Query: 278 ELGKDGRSCVTSG--EGQPTLGG 298
            L  D  +C +       P  GG
Sbjct: 292 RLLDDLVTCASRNPCSSSPCRGG 314



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 24/83 (28%), Positives = 33/83 (39%), Gaps = 23/83 (27%)

Query: 213 SALCRGQLPISVTCIADEIGARWDKLSGDVLCPCPGRY---------LRAGKCAELP--- 260
           S+ CRG      TC+    G  +        C CP  Y         +   +C + P   
Sbjct: 308 SSPCRG----GATCVLGPHGKNYT-------CRCPQGYQLDSSQLDCVDVDECQDSPCAQ 356

Query: 261 NCLDDLGGFACECATGFELGKDG 283
            C++  GGF CEC  G+E G  G
Sbjct: 357 ECVNTPGGFRCECWVGYEPGGPG 379



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 59/242 (24%), Positives = 90/242 (37%), Gaps = 66/242 (27%)

Query: 240 GDVLCPCPGRYLRAGK----CAELPNCL-------DDL-----GGFACECATGFELGKDG 283
           G   C C   Y+ AG+    C ++  C+       D L     G F C C  G+ L  +G
Sbjct: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNG 464

Query: 284 RSCVTSGEGQPTLGGTGVPTRRPPATATSPVPQRTWPIRVDEKLGETPLVPEQDNSVTSI 343
            SC     G  +LG    P   PP                 EK G T  VP    +  S 
Sbjct: 465 VSCTM---GPVSLG----PPSGPPDEEDK-----------GEKEGST--VPRA--ATASP 502

Query: 344 PEIPRWGSQSTMSTLQMSLQAESKAT------ITPSGS-------VISKFNSTTSSATPQ 390
              P    ++T +T + SL +++  T      + PSGS        I    + +    P 
Sbjct: 503 TRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPA 562

Query: 391 AFDSSSA------------VVFIFVSTAVVVLVILTMTVLGLVKLCFHESPSSQPRKESM 438
             DSS A            ++F  + T V +L++L +  LGL  L + +  + +  K+  
Sbjct: 563 GGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLAL-ALGL--LVYRKRRAKREEKKEK 619

Query: 439 GP 440
            P
Sbjct: 620 KP 621


>gi|4507483 thrombomodulin precursor [Homo sapiens]
          Length = 575

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 77/285 (27%), Positives = 113/285 (39%), Gaps = 35/285 (12%)

Query: 16  PGPGGGEHPTADRAGCSASGACYSLHHATMKRQAAEEACILRGGALSTVRAGAELRAVLA 75
           P PGG +    D         C++L+        A + C    G L TVR+      +  
Sbjct: 23  PQPGGSQCVEHD---------CFALYPGPATFLNASQICDGLRGHLMTVRSSVAADVISL 73

Query: 76  LLRAGPGPGGGSKDLLFWVALERRRSHCTLEN-EPLRGFSWLSSDPGGLESDTLQWVEEP 134
           LL    G GG  +  L W+ L+        +   PLRGF W++ D     S   +     
Sbjct: 74  LLN---GDGGVGRRRL-WIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYSRWARLDLNG 129

Query: 135 QRSCTARRCAV--LQATGGVEPAGWKEMRCHLRANGYLCKYQFEVLCP--APRPGAAS-- 188
              C     AV   +AT   EP  W+E +C ++A+G+LC++ F   C   A  PGAA+  
Sbjct: 130 APLCGPLCVAVSAAEATVPSEPI-WEEQQCEVKADGFLCEFHFPATCRPLAVEPGAAAAA 188

Query: 189 -NLSYRAPFQLHSAALDFSPPGTEVSALCRGQLPISVTCIADEIGARWDKLSGDVLCPCP 247
            +++Y  PF    A     P G+  +    G L +  T     +   W +         P
Sbjct: 189 VSITYGTPFAARGADFQALPVGSSAAVAPLG-LQLMCTAPPGAVQGHWAR-------EAP 240

Query: 248 GRY---LRAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTS 289
           G +   +  G C    N +   G   C+C  G  L  DGRSC  S
Sbjct: 241 GAWDCSVENGGCEHACNAIP--GAPRCQCPAGAALQADGRSCTAS 283


>gi|20127636 chondrolectin precursor [Homo sapiens]
          Length = 273

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 16/143 (11%)

Query: 48  QAAEEACILRGGALSTVRAGAELRAVLALLRAGPGPGGGSKDLLFWVALERRRSHCTLEN 107
           Q A  AC   GG L ++   AE + + ++L+    PG G  D  FW+ L R     T   
Sbjct: 55  QEARLACESEGGVLLSLENEAEQKLIESMLQNLTKPGTGISDGDFWIGLWRNGDGQTSGA 114

Query: 108 EPLRGFSWLSSDPGGLESDTLQW-VEEPQRSCTARRCAVL-------QATGGVEPAGWKE 159
            P   + W  SD  G  S    W  +EP  SC + +C V+          GG     W +
Sbjct: 115 CP-DLYQW--SD--GSNSQYRNWYTDEP--SCGSEKCVVMYHQPTANPGLGGPYLYQWND 167

Query: 160 MRCHLRANGYLCKYQFEVLCPAP 182
            RC+++ N Y+CKY+ E+   AP
Sbjct: 168 DRCNMKHN-YICKYEPEINPTAP 189


>gi|190343004 EGF-containing fibulin-like extracellular matrix
           protein 2 [Homo sapiens]
          Length = 443

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 10/64 (15%)

Query: 238 LSGDVLCPCPGRYLRAG-KCAELPNC---------LDDLGGFACECATGFELGKDGRSCV 287
           L G   C CP  Y + G +C ++  C         ++  G F C+C  GF+LG + RSCV
Sbjct: 143 LPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCV 202

Query: 288 TSGE 291
              E
Sbjct: 203 DVNE 206



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 12/25 (48%), Positives = 15/25 (60%)

Query: 262 CLDDLGGFACECATGFELGKDGRSC 286
           C +  G F C C  G+EL +DG SC
Sbjct: 217 CFNSYGTFLCRCHQGYELHRDGFSC 241


>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
          Length = 933

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/35 (51%), Positives = 21/35 (60%)

Query: 256 CAELPNCLDDLGGFACECATGFELGKDGRSCVTSG 290
           C     C +  GGF C CA  +ELG DGR+CV SG
Sbjct: 808 CHASARCRNTKGGFQCLCADPYELGDDGRTCVDSG 842


>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
          Length = 876

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/35 (51%), Positives = 21/35 (60%)

Query: 256 CAELPNCLDDLGGFACECATGFELGKDGRSCVTSG 290
           C     C +  GGF C CA  +ELG DGR+CV SG
Sbjct: 751 CHASARCRNTKGGFQCLCADPYELGDDGRTCVDSG 785


>gi|28558990 thyroid peroxidase isoform e [Homo sapiens]
          Length = 760

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/35 (51%), Positives = 21/35 (60%)

Query: 256 CAELPNCLDDLGGFACECATGFELGKDGRSCVTSG 290
           C     C +  GGF C CA  +ELG DGR+CV SG
Sbjct: 635 CHASARCRNTKGGFQCLCADPYELGDDGRTCVDSG 669


>gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens]
          Length = 4655

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 33/107 (30%)

Query: 207  PPGTEVSALCRGQLPISVT------CIADEIGARWDKLSGDVLCPCPGRYLRA------- 253
            P GT+ S LC G             C+ +  GA+         C CP  +L A       
Sbjct: 1339 PNGTDESPLCNGNSCSDFNGGCTHECVQEPFGAK---------CLCPLGFLLANDSKTCE 1389

Query: 254  --------GKCAELPNCLDDLGGFACECATGFELGKDGRSC-VTSGE 291
                    G C++  +C +  G F C C TG+ L  DGR+C VT+ E
Sbjct: 1390 DIDECDILGSCSQ--HCYNMRGSFRCSCDTGYMLESDGRTCKVTASE 1434



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 16/26 (61%), Positives = 18/26 (69%), Gaps = 1/26 (3%)

Query: 262  CLDDLGG-FACECATGFELGKDGRSC 286
            CL   GG F+C CATGF+L  D RSC
Sbjct: 2033 CLPVPGGLFSCACATGFKLNPDNRSC 2058



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 14/31 (45%), Positives = 17/31 (54%)

Query: 261  NCLDDLGGFACECATGFELGKDGRSCVTSGE 291
            NC D L  F C C  G++L  D R+CV   E
Sbjct: 3125 NCTDTLTSFYCSCRPGYKLMSDKRTCVDIDE 3155



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 14/67 (20%)

Query: 244  CPC-PGRYLRAGK--------CAELP-----NCLDDLGGFACECATGFELGKDGRSCVTS 289
            C C PG  L + K        C E+P      C + +G + C+CA G+    DG++C  +
Sbjct: 3135 CSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPGYLREPDGKTCRQN 3194

Query: 290  GEGQPTL 296
               +P L
Sbjct: 3195 SNIEPYL 3201



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 10/20 (50%), Positives = 13/20 (65%)

Query: 268 GFACECATGFELGKDGRSCV 287
           GF C+C  GF+L  D R C+
Sbjct: 686 GFRCKCTFGFQLDTDERHCI 705


>gi|22547221 tolloid-like 1 [Homo sapiens]
          Length = 1013

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 28/69 (40%), Positives = 33/69 (47%), Gaps = 11/69 (15%)

Query: 244 CPCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGEGQPT-LGGT--- 299
           C  P R    G C +   CL+ LG + C C  G+ELG D RSC  +  G  T L GT   
Sbjct: 578 CAKPDR----GGCEQ--RCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITT 631

Query: 300 -GVPTRRPP 307
            G P   PP
Sbjct: 632 PGWPKEYPP 640


>gi|56237021 fibrillin 3 precursor [Homo sapiens]
          Length = 2809

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 1/49 (2%)

Query: 254  GKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTGVP 302
            G+     +CL+  G F C C  GFEL  DG++CV + E   +L GT +P
Sbjct: 1895 GQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECL-SLAGTCLP 1942



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 253 AGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGE 291
           +G    L  C++  G F C C  GFEL  DG++CV   E
Sbjct: 496 SGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNE 534



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 20/71 (28%), Positives = 26/71 (36%), Gaps = 14/71 (19%)

Query: 236  DKLSGDVLCPCPGRY---LRAGKCAELPNCLDDL-----------GGFACECATGFELGK 281
            + L G   C C G Y      G C ++  C D +           G + C C   FEL  
Sbjct: 1420 ENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNP 1479

Query: 282  DGRSCVTSGEG 292
             G  CV +  G
Sbjct: 1480 SGVGCVDTRAG 1490



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 36/165 (21%), Positives = 56/165 (33%), Gaps = 43/165 (26%)

Query: 175  FEVLCPAPRPGAASNLSYRAPFQLHSAALDFSPPGTEVSALCRGQL-------------- 220
            +++LC    PG  +++    P  +         P    + +C  Q+              
Sbjct: 1699 YQILCGNQAPGFLTDIHTGKPLDIDECG---EIPAICANGICINQIGSFRCECPAGFNYN 1755

Query: 221  PISVTCI-ADEIGARWD---------KLSGDVLCPCPGRY--------LRAGKCAELPN- 261
             I + C   DE G+R            + G   C C   Y        +   +C E+PN 
Sbjct: 1756 SILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNV 1815

Query: 262  -----CLDDLGGFACECATGFELGKDGRSCVTSGE--GQPTLGGT 299
                 C+D  G + C C  GF+   D   C+   E   QP   GT
Sbjct: 1816 CSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT 1860



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 14/61 (22%)

Query: 240  GDVLCPCPGRY---------LRAGKCAELPN-----CLDDLGGFACECATGFELGKDGRS 285
            G   C C   Y         L   +C+++P      C +  G F C C  G+ L +DGR+
Sbjct: 2384 GSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRT 2443

Query: 286  C 286
            C
Sbjct: 2444 C 2444



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 13/62 (20%)

Query: 238  LSGDVLCPCPGRY-------LRAGKCAELPN------CLDDLGGFACECATGFELGKDGR 284
            L G   C CP  +       +   +C+E PN      C +  G F C C  GF L  +G 
Sbjct: 1948 LEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGH 2007

Query: 285  SC 286
             C
Sbjct: 2008 RC 2009



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 9/54 (16%)

Query: 255  KCAELPN------CLDDLGGFACECATGFELGKDGRSCVTSGE---GQPTLGGT 299
            +CAE P       C++  G F CEC  G+ L   G +CV + E   G P   GT
Sbjct: 2087 ECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2140



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 6/38 (15%)

Query: 255  KCAELP------NCLDDLGGFACECATGFELGKDGRSC 286
            +C ELP      +C++  G F CEC  G+ L +  R C
Sbjct: 1566 ECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRIC 1603



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 12/27 (44%), Positives = 16/27 (59%)

Query: 261 NCLDDLGGFACECATGFELGKDGRSCV 287
           +C +  G F C+C  G  +G DGR CV
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDGRVCV 612



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 2/48 (4%)

Query: 261  NCLDDLGGFACECATGFELGKDGRSC--VTSGEGQPTLGGTGVPTRRP 306
            +C++  G + C C  G+ L  DGR+C  V   E  P +   G  T  P
Sbjct: 1169 HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMP 1216



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 12/25 (48%), Positives = 17/25 (68%)

Query: 262  CLDDLGGFACECATGFELGKDGRSC 286
            CL+  GG+ CEC  GF+  +D R+C
Sbjct: 1378 CLNAPGGYRCECEMGFDPTEDHRAC 1402



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 14/40 (35%), Positives = 20/40 (50%)

Query: 262  CLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTGV 301
            C++ +G F C C  GF+   D + CV   E +   GG  V
Sbjct: 1129 CVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDV 1168



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 2/47 (4%)

Query: 262  CLDDLGGFACECATGFELGKDGRSCVTSGEGQ--PTLGGTGVPTRRP 306
            C + +G F C CA GF L    R+C    E +  P L G G     P
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTP 1048



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 13/33 (39%), Positives = 15/33 (45%)

Query: 254  GKCAELPNCLDDLGGFACECATGFELGKDGRSC 286
            G C    +C +  G F CEC  GF L   G  C
Sbjct: 2494 GPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC 2526



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 12/26 (46%), Positives = 14/26 (53%)

Query: 262 CLDDLGGFACECATGFELGKDGRSCV 287
           C++  G F CEC  G  L   GR CV
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCV 910



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 13/32 (40%), Positives = 17/32 (53%)

Query: 262 CLDDLGGFACECATGFELGKDGRSCVTSGEGQ 293
           CL++ G F+C C  GF L   G  C+   E Q
Sbjct: 546 CLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ 577



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 11/19 (57%), Positives = 13/19 (68%)

Query: 262  CLDDLGGFACECATGFELG 280
            C + +GGF C CA GFE G
Sbjct: 2141 CTNVIGGFECACADGFEPG 2159



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 14/39 (35%), Positives = 16/39 (41%), Gaps = 3/39 (7%)

Query: 262  CLDDLGGFACECATGFELGKDGRSCVTSGE---GQPTLG 297
            C + LGG+ C C  GF        CV   E     PT G
Sbjct: 2542 CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580


>gi|24430141 fibrillin 1 precursor [Homo sapiens]
          Length = 2871

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 14/76 (18%)

Query: 239  SGDVLCPC-PG-RYLRAGKC------AELPN------CLDDLGGFACECATGFELGKDGR 284
            +G   C C PG R+   G+C       E+PN      C+D +G F C C TGF+   D  
Sbjct: 1828 AGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQT 1887

Query: 285  SCVTSGEGQPTLGGTG 300
             C+   E +    G G
Sbjct: 1888 MCLDINECERDACGNG 1903



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 13/30 (43%), Positives = 20/30 (66%)

Query: 262  CLDDLGGFACECATGFELGKDGRSCVTSGE 291
            C++ +G F C+C  G+E+  DGR+CV   E
Sbjct: 1947 CINTVGSFQCQCNEGYEVAPDGRTCVDINE 1976



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 13/62 (20%)

Query: 238  LSGDVLCPCPGRY-LRAGKCAELPNCLDDL------------GGFACECATGFELGKDGR 284
            L G   C CP  Y L+  KC ++  C+++             G F C C  GF L   GR
Sbjct: 1992 LDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGR 2051

Query: 285  SC 286
             C
Sbjct: 2052 RC 2053



 Score = 35.8 bits (81), Expect = 0.091
 Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 7/53 (13%)

Query: 255  KCAELPN------CLDDLGGFACECATGFELGKDGRSCVTSGEGQ-PTLGGTG 300
            +C ELP       C++  G F C C TG+ L +D R C    E + P + G G
Sbjct: 1609 ECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPG 1661



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 6/57 (10%)

Query: 248 GRYLRAGKCAELPN------CLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGG 298
           GRY +     E P       C++  G + CEC  G  +G DGR CV +       GG
Sbjct: 608 GRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGG 664



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 13/60 (21%)

Query: 240  GDVLCPCPGRYLRAG-KCAELPNCLDDL------------GGFACECATGFELGKDGRSC 286
            G   C C   Y   G  C +L  C ++L            GG+ CEC  GF    DG++C
Sbjct: 1385 GSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKAC 1444



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 12/25 (48%), Positives = 16/25 (64%)

Query: 262 CLDDLGGFACECATGFELGKDGRSC 286
           C+++ G F C C  GF+L  DGR C
Sbjct: 587 CINEDGSFKCICKPGFQLASDGRYC 611



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 12/53 (22%)

Query: 240  GDVLCPCPGRYLRAG-KCAELPNCL-----------DDLGGFACECATGFELG 280
            G   C CP  Y+ AG +C +   C            + +GGF C C  GFE G
Sbjct: 2147 GSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPG 2199



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 12/36 (33%), Positives = 20/36 (55%)

Query: 251 LRAGKCAELPNCLDDLGGFACECATGFELGKDGRSC 286
           L+ G+      C++  G F C C  GF + +DG++C
Sbjct: 535 LQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNC 570



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 18/61 (29%), Positives = 23/61 (37%), Gaps = 14/61 (22%)

Query: 240  GDVLCPCPGRYLRAG-KCAELPNCLDDL-------------GGFACECATGFELGKDGRS 285
            G   C CP  + +    C +   C  D+             G F CEC  GF L + G S
Sbjct: 2505 GGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSS 2564

Query: 286  C 286
            C
Sbjct: 2565 C 2565



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 2/47 (4%)

Query: 262  CLDDLGGFACECATGFELGKDGRSCVTSGEGQ--PTLGGTGVPTRRP 306
            C + +G F C C +GF L  + R+C    E +  P L G G     P
Sbjct: 1044 CRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTP 1090



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 33/141 (23%), Positives = 50/141 (35%), Gaps = 35/141 (24%)

Query: 215 LCRGQLPISV---TCIADEIGARWDKLSGDVLCPCPGRYLRAG--------------KCA 257
           +C+GQL   V   T     +G  W       +CP      R G              +C 
Sbjct: 194 MCQGQLSGIVCTKTLCCATVGRAWGHPCE--MCPAQPHPCRRGFIPNIRTGACQDVDECQ 251

Query: 258 ELP------NCLDDLGGFACECATGFELGKDGRSCVTSGE----------GQPTLGGTGV 301
            +P      NC++ +G F C+C  G +L +  + C    E          G+ T   +  
Sbjct: 252 AIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSY 311

Query: 302 PTRRPPATATSPVPQRTWPIR 322
             + PP   TSP   R   +R
Sbjct: 312 FCKCPPGFYTSPDGTRCIDVR 332



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 15/38 (39%), Positives = 18/38 (47%), Gaps = 6/38 (15%)

Query: 254  GKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGE 291
            G C  LP      G F CEC  G+EL + G +C    E
Sbjct: 1459 GTCHNLP------GLFRCECEIGYELDRSGGNCTDVNE 1490



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 24/94 (25%), Positives = 35/94 (37%), Gaps = 34/94 (36%)

Query: 216  CRGQLPISVT----CIADEIGARWDKLSGDVLCPCP----------------------GR 249
            C G+L  ++T    C +  IG  W+K      CP P                      G 
Sbjct: 1706 CDGELLFNMTKKMCCCSYNIGRAWNKPCEQ--CPIPSTDEFATLCGSQRPGFVIDIYTGL 1763

Query: 250  YLRAGKCAELPN------CLDDLGGFACECATGF 277
             +   +C E+P       C++ +G F CEC  GF
Sbjct: 1764 PVDIDECREIPGVCENGVCINMVGSFRCECPVGF 1797



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 16/66 (24%)

Query: 240  GDVLCPCPGRYLR---AGKCAELPNC-----------LDDLGGFACECATGFELGKDGRS 285
            G   C CP  Y+       C +L  C           ++ +GGF C+C  GF   +   S
Sbjct: 2464 GSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFT--QHHTS 2521

Query: 286  CVTSGE 291
            C+ + E
Sbjct: 2522 CIDNNE 2527



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 29/118 (24%), Positives = 44/118 (37%), Gaps = 18/118 (15%)

Query: 207  PPGTEVSALCRGQLPISVTCIADEI--GARWDKLSGDVLCPC-PGRYLRAGK--CAELPN 261
            PPG ++S      + I+   ++  +    R   L G   C C PG +    +  C ++  
Sbjct: 1141 PPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1200

Query: 262  C-----------LDDLGGFACECATGFELGKDGRSC--VTSGEGQPTLGGTGVPTRRP 306
            C            +  G + C C  GF L  D RSC  +   E  P +   G  T  P
Sbjct: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIP 1258



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 3/63 (4%)

Query: 230  EIGARWDKLSGDVLCPCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTS 289
            EIG   D+  G+  C      L    C    NC++  G + C+C   FEL      CV +
Sbjct: 1473 EIGYELDRSGGN--CTDVNECLDPTTCIS-GNCVNTPGSYICDCPPDFELNPTRVGCVDT 1529

Query: 290  GEG 292
              G
Sbjct: 1530 RSG 1532



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 5/42 (11%)

Query: 255  KCAELP-----NCLDDLGGFACECATGFELGKDGRSCVTSGE 291
            +CA+ P      C++  G + C+C  G+ L +D R C    E
Sbjct: 2209 ECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDE 2250



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 19/70 (27%), Positives = 26/70 (37%), Gaps = 15/70 (21%)

Query: 238  LSGDVLCPCPGRYLRA---------GKCAELPN------CLDDLGGFACECATGFELGKD 282
            L G  +C C   Y R           +C   P       CL+  G + CEC  GF    +
Sbjct: 2268 LIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPN 2327

Query: 283  GRSCVTSGEG 292
               C+ + EG
Sbjct: 2328 QDECLDNREG 2337



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 11/25 (44%), Positives = 15/25 (60%)

Query: 262  CLDDLGGFACECATGFELGKDGRSC 286
            C +  G + C C  G+ L +DGRSC
Sbjct: 2459 CKNTEGSYQCSCPKGYILQEDGRSC 2483



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 12/30 (40%), Positives = 16/30 (53%)

Query: 262  CLDDLGGFACECATGFELGKDGRSCVTSGE 291
            C++D G + C C TG+     G SCV   E
Sbjct: 2418 CVNDRGSYHCICKTGYTPDITGTSCVDLNE 2447



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 10/26 (38%), Positives = 15/26 (57%)

Query: 262 CLDDLGGFACECATGFELGKDGRSCV 287
           C++  G F C+C +G  L   GR C+
Sbjct: 926 CVNTRGSFKCQCPSGMTLDATGRICL 951



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 12/36 (33%), Positives = 17/36 (47%)

Query: 262  CLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLG 297
            C + +G + C C  G++   DG  CV   E Q   G
Sbjct: 2265 CKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPG 2300


>gi|86788132 EGF-containing fibulin-like extracellular matrix
           protein 1 precursor [Homo sapiens]
          Length = 493

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 14/77 (18%)

Query: 226 CIADEIGARWDKLSGDVLCPCPGRYLRAGK-CAELPNC----------LDDLGGFACECA 274
           C AD++      L G   C CP  Y + G+ C ++  C          ++  G F C+C+
Sbjct: 184 CRADQVCIN---LRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCS 240

Query: 275 TGFELGKDGRSCVTSGE 291
            GF+L  +  +CV   E
Sbjct: 241 PGFQLAANNYTCVDINE 257



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 13/34 (38%), Positives = 20/34 (58%), Gaps = 2/34 (5%)

Query: 253 AGKCAELPNCLDDLGGFACECATGFELGKDGRSC 286
           + +CA+   C + LG F C+C  G+EL  D  +C
Sbjct: 261 SNQCAQ--QCYNILGSFICQCNQGYELSSDRLNC 292


>gi|86788015 EGF-containing fibulin-like extracellular matrix
           protein 1 precursor [Homo sapiens]
          Length = 493

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 14/77 (18%)

Query: 226 CIADEIGARWDKLSGDVLCPCPGRYLRAGK-CAELPNC----------LDDLGGFACECA 274
           C AD++      L G   C CP  Y + G+ C ++  C          ++  G F C+C+
Sbjct: 184 CRADQVCIN---LRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCS 240

Query: 275 TGFELGKDGRSCVTSGE 291
            GF+L  +  +CV   E
Sbjct: 241 PGFQLAANNYTCVDINE 257



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 13/34 (38%), Positives = 20/34 (58%), Gaps = 2/34 (5%)

Query: 253 AGKCAELPNCLDDLGGFACECATGFELGKDGRSC 286
           + +CA+   C + LG F C+C  G+EL  D  +C
Sbjct: 261 SNQCAQ--QCYNILGSFICQCNQGYELSSDRLNC 292


>gi|9665262 EGF-containing fibulin-like extracellular matrix protein
           1 precursor [Homo sapiens]
          Length = 493

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 14/77 (18%)

Query: 226 CIADEIGARWDKLSGDVLCPCPGRYLRAGK-CAELPNC----------LDDLGGFACECA 274
           C AD++      L G   C CP  Y + G+ C ++  C          ++  G F C+C+
Sbjct: 184 CRADQVCIN---LRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCS 240

Query: 275 TGFELGKDGRSCVTSGE 291
            GF+L  +  +CV   E
Sbjct: 241 PGFQLAANNYTCVDINE 257



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 13/34 (38%), Positives = 20/34 (58%), Gaps = 2/34 (5%)

Query: 253 AGKCAELPNCLDDLGGFACECATGFELGKDGRSC 286
           + +CA+   C + LG F C+C  G+EL  D  +C
Sbjct: 261 SNQCAQ--QCYNILGSFICQCNQGYELSSDRLNC 292


>gi|66346695 fibrillin 2 precursor [Homo sapiens]
          Length = 2912

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 27/93 (29%), Positives = 36/93 (38%), Gaps = 33/93 (35%)

Query: 216  CRGQLPISVT----CIADEIGARWDKLSGDVLCPCPGRY---------------LRAGK- 255
            C  +LP +VT    C    +G  W+K      CP PG                 +  GK 
Sbjct: 1749 CENELPFNVTKRMCCCTYNVGKAWNKPCEP--CPTPGTADFKTICGNIPGFTFDIHTGKA 1806

Query: 256  -----CAELPN------CLDDLGGFACECATGF 277
                 C E+P       C++ +G F CEC TGF
Sbjct: 1807 VDIDECKEIPGICANGVCINQIGSFRCECPTGF 1839



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 9/80 (11%)

Query: 240 GDVLCPCPGRYLRAGKCAELP------NCLDDLGGFACECATGFELGKDGRSCVTSGEGQ 293
           G VL P  GRY       + P      +C++  G F C+C  G  +G DGR CV +    
Sbjct: 646 GFVLAP-NGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 704

Query: 294 PTLGG--TGVPTRRPPATAT 311
              GG   GV  R  P   T
Sbjct: 705 TCYGGIKKGVCVRPFPGAVT 724



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 13/62 (20%)

Query: 238  LSGDVLCPCPGRY-------LRAGKCAELPN------CLDDLGGFACECATGFELGKDGR 284
            L G   C CP  Y       +   +C E PN      C +  GGF C C  GF L  +GR
Sbjct: 2035 LEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGR 2094

Query: 285  SC 286
             C
Sbjct: 2095 RC 2096



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 6/38 (15%)

Query: 255  KCAELP------NCLDDLGGFACECATGFELGKDGRSC 286
            +C ELP      NC++  G F CEC  G+ L +D R C
Sbjct: 1653 ECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRIC 1690



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 13/38 (34%), Positives = 22/38 (57%)

Query: 254  GKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGE 291
            G+      C +++G F C C  G+EL  DG++C+ + E
Sbjct: 1982 GQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNE 2019



 Score = 36.6 bits (83), Expect = 0.053
 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 9/75 (12%)

Query: 240  GDVLCPCPGRYLRAGKCAELPN------CLDDLGGFACECATGFELGKDGRSCVTSGEGQ 293
            GDVL   P  Y    +C   P       C + +G F C C +GF L  + R+C    E +
Sbjct: 1062 GDVLTGRPF-YKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECR 1120

Query: 294  --PTLGGTGVPTRRP 306
              P L G+G+    P
Sbjct: 1121 ISPDLCGSGICVNTP 1135



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 14/30 (46%), Positives = 18/30 (60%)

Query: 262 CLDDLGGFACECATGFELGKDGRSCVTSGE 291
           C++  G F C C  GFEL  DG++CV   E
Sbjct: 591 CVNTDGSFQCICNAGFELTTDGKNCVDHDE 620



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 13/66 (19%)

Query: 240 GDVLCPCPGRYL---------RAGKCAELP----NCLDDLGGFACECATGFELGKDGRSC 286
           G   C CP  Y+            +C   P     C ++LG F CEC+ G +L   G  C
Sbjct: 831 GSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLIC 890

Query: 287 VTSGEG 292
           + S +G
Sbjct: 891 IDSLKG 896



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 25/112 (22%)

Query: 198  LHSAALDFSPPGTEVSALCRGQLPISVTCI-ADE---------IGARWDKLSGDVLCPCP 247
            +H++ L+   PG+   +   G +   + CI  DE         I A+     G   C C 
Sbjct: 1380 MHASCLNI--PGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACS 1437

Query: 248  GRYLRAG-------KCAELPN------CLDDLGGFACECATGFELGKDGRSC 286
              +   G       +CAE  N      CL+  G + CEC  GF    D RSC
Sbjct: 1438 EGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSC 1489



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 1/36 (2%)

Query: 256  CAELPNCLDDLGGFACECATGFELGKDGRSCVTSGE 291
            C    +C++  G + CECA GF+L  +G +CV   E
Sbjct: 1861 CQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNE 1895



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 19/76 (25%), Positives = 29/76 (38%), Gaps = 15/76 (19%)

Query: 232  GARWDKLSGDVLCPCPGRYLRA---------GKCAELPN------CLDDLGGFACECATG 276
            G     L G  +C CP    R           +C   P       C++ +G + CEC  G
Sbjct: 2309 GMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEG 2368

Query: 277  FELGKDGRSCVTSGEG 292
            F+    G  C+ + +G
Sbjct: 2369 FQSSSSGTECLDNRQG 2384



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 19/84 (22%)

Query: 240  GDVLCPCPGRYL--RAGK-CAELPNC-----------LDDLGGFACECATGFELGKDGRS 285
            G   C CP  Y+    GK C +L  C           ++ LGGF C+C  GF   +   +
Sbjct: 2511 GSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFT--QHHTA 2568

Query: 286  CVTSGE--GQPTL-GGTGVPTRRP 306
            C+ + E   QP+L G  G+    P
Sbjct: 2569 CIDNNECGSQPSLCGAKGICQNTP 2592



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 9/82 (10%)

Query: 226  CIADEIGARWDKLSGDVLCPCPGRYLRAGKCAELPN------CLDDLGGFACECATGFEL 279
            CI      R +  +G  L P  G  +   +C E+PN      C+D  G + C C  GF+ 
Sbjct: 1867 CINSPGSYRCECAAGFKLSP-NGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKA 1925

Query: 280  GKDGRSC--VTSGEGQPTLGGT 299
             +D   C  V   E  P   GT
Sbjct: 1926 SQDQTMCMDVDECERHPCGNGT 1947



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 9/54 (16%)

Query: 255  KCAELPN------CLDDLGGFACECATGFELGKDGRSCVTSGE---GQPTLGGT 299
            +C E P       C++  G F CEC  G+ L   G  CV + E   G P   GT
Sbjct: 2174 ECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGT 2227



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 2/47 (4%)

Query: 262  CLDDLGGFACECATGFELGKDGRSC--VTSGEGQPTLGGTGVPTRRP 306
            C +  G + C C+ G+ L  DGRSC  +   E  P +   G  T  P
Sbjct: 1257 CTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIP 1303



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 10/59 (16%)

Query: 243  LCPCPGRYLRAGK----CAELPN------CLDDLGGFACECATGFELGKDGRSCVTSGE 291
            +CP    Y   G+    C  +PN      C++ +G F C C  G+     G SC+   E
Sbjct: 2436 ICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDE 2494



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 13/32 (40%), Positives = 17/32 (53%)

Query: 262 CLDDLGGFACECATGFELGKDGRSCVTSGEGQ 293
           C+++ G F C C  GF L  +GR C    E Q
Sbjct: 632 CINEDGSFKCICKPGFVLAPNGRYCTDVDECQ 663



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 16/73 (21%)

Query: 231 IGARW----DKLSGDVLCPCPGRYLRAGKCAEL----------PN--CLDDLGGFACECA 274
           +GA W    ++   D  CP     ++   C ++          PN  C++  G F CEC 
Sbjct: 924 LGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECP 983

Query: 275 TGFELGKDGRSCV 287
            G  L   GR C+
Sbjct: 984 EGLTLDGTGRVCL 996



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 17/61 (27%), Positives = 24/61 (39%), Gaps = 14/61 (22%)

Query: 240  GDVLCPCPGRYLRA-------GKCAELPN-------CLDDLGGFACECATGFELGKDGRS 285
            G   C CP  + +         +C   P+       C +  G F+CEC  GF L   G +
Sbjct: 2552 GGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLN 2611

Query: 286  C 286
            C
Sbjct: 2612 C 2612



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 23/90 (25%), Positives = 35/90 (38%), Gaps = 11/90 (12%)

Query: 215  LCRGQLPISVTCIADEIGARWDKLSGDVLCPCPGRYLRAGKCAELPN------CLDDLGG 268
            LCRG      TC+  E   + D   G  L P     +   +C+   N      C++ +G 
Sbjct: 1168 LCRGG-----TCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGT 1222

Query: 269  FACECATGFELGKDGRSCVTSGEGQPTLGG 298
            + C C  G++   D + C    E     GG
Sbjct: 1223 YQCSCNPGYQATPDRQGCTDIDECMIMNGG 1252



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 14/78 (17%)

Query: 220  LPISVTCIADEIGARWDKLSGDVLCPCPGRYLRAGKCAELPNCLDDL-----GGFACECA 274
            LP    CI D+ G   D+  G+             +CA+  NC++ L     G + C C 
Sbjct: 1509 LPGMFHCICDD-GYELDRTGGNCT--------DIDECADPINCVNGLCVNTPGRYECNCP 1559

Query: 275  TGFELGKDGRSCVTSGEG 292
              F+L   G  CV +  G
Sbjct: 1560 PDFQLNPTGVGCVDNRVG 1577



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 13/44 (29%), Positives = 22/44 (50%), Gaps = 5/44 (11%)

Query: 255  KCAELPN-----CLDDLGGFACECATGFELGKDGRSCVTSGEGQ 293
            +C++ P      C +  G + C C  G+ L +DG++C    E Q
Sbjct: 2494 ECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQ 2537


>gi|21264602 laminin alpha 5 [Homo sapiens]
          Length = 3695

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 59/229 (25%), Positives = 81/229 (35%), Gaps = 55/229 (24%)

Query: 120  PGGLESDTLQWVEEPQRSCTAR----RCAVLQATGGVEPAGWKEMRCHLRANGYLCKYQF 175
            PG +    LQ VE   R    R    R  ++     +E    + +   + +  +L +   
Sbjct: 1754 PGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQIRALFSQISSAVFLRRVAL 1813

Query: 176  EVLCPAPRPGAASNL-------SYRA-----------------------PFQLHSAALDF 205
            EV  PA +   ASN+       SYR                        P Q H  + D 
Sbjct: 1814 EVASPAGQGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHS-DR 1872

Query: 206  SPPGTEVSALCRGQLPIS--VTCIADEIGARWDKLSGDVLCPCP----------GRYLRA 253
              PG+ V   C+     +    C A  + +R D  +  V CPCP          G  LR 
Sbjct: 1873 CLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRG 1932

Query: 254  GKCAELPNCLDDLGGFACE-CATGF-----ELGKDGRSCVTSGEGQPTL 296
            G+   L  C     G +CE CA GF      LG   + C  SG G P L
Sbjct: 1933 GRTQCL--CKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNL 1979


>gi|19743803 fibulin 5 precursor [Homo sapiens]
          Length = 448

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 40/153 (26%), Positives = 60/153 (39%), Gaps = 28/153 (18%)

Query: 159 EMRCHLRANGYLCKYQFEVLCPAPRPGAASNLSYRAPFQLHSAALDFSPPGTEVSA---L 215
           +M C  +  GYLC  +   +   P     S   Y  P+   +AA   S P     +   +
Sbjct: 56  DMMCVNQNGGYLCIPRTNPVYRGPYSNPYST-PYSGPYP--AAAPPLSAPNYPTISRPLI 112

Query: 216 CRG--QLPISVTCI-ADEIGARWDKLS---------GDVLCPCP-GRYLRAGKCAELPNC 262
           CR   Q+  S  C+  DE      + +         G   C C  G +L  G+C ++  C
Sbjct: 113 CRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDEC 172

Query: 263 ---------LDDLGGFACECATGFELGKDGRSC 286
                     +  G ++C C  GF L +DGRSC
Sbjct: 173 RYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSC 205



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 11/25 (44%), Positives = 15/25 (60%)

Query: 262 CLDDLGGFACECATGFELGKDGRSC 286
           C++  G F C C  G+EL +DG  C
Sbjct: 221 CVNTYGSFICRCDPGYELEEDGVHC 245


>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
          Length = 1541

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 16/32 (50%), Positives = 19/32 (59%), Gaps = 2/32 (6%)

Query: 255 KCAELPNCLDDLGGFACECATGFELGKDGRSC 286
           +CA    CL+  G F C C  G+ELG DGR C
Sbjct: 295 QCAH--GCLNTQGSFKCVCHAGYELGADGRQC 324



 Score = 36.2 bits (82), Expect = 0.070
 Identities = 22/73 (30%), Positives = 29/73 (39%), Gaps = 13/73 (17%)

Query: 239 SGDVLCPCPGRY---------LRAGKCAELPNC----LDDLGGFACECATGFELGKDGRS 285
           S   LC CP  Y         +    CA+ P C     ++ GG+ C C  G+ L  DG  
Sbjct: 350 SAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCG 409

Query: 286 CVTSGEGQPTLGG 298
           C    E   + GG
Sbjct: 410 CEDVDECASSRGG 422



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 11/26 (42%), Positives = 16/26 (61%)

Query: 262 CLDDLGGFACECATGFELGKDGRSCV 287
           C++  G + CEC  GF L  D R+C+
Sbjct: 176 CVNTPGSYLCECKPGFRLHTDSRTCL 201



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 15/63 (23%)

Query: 240 GDVLCPC-PGRYLRAGK--CAELPNCLDDLGG------------FACECATGFELGKDGR 284
           G  LC C PG  L      C  + +C    GG              C+C  GF+L +DGR
Sbjct: 181 GSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGR 240

Query: 285 SCV 287
            CV
Sbjct: 241 HCV 243



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 1/46 (2%)

Query: 261 NCLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTGVPTRRP 306
           +C +  G F C C  G+ L +D R C    E    L G  +P  RP
Sbjct: 426 HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGE-LPFVRP 470


>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
          Length = 988

 Score = 37.4 bits (85), Expect = 0.031
 Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 8/102 (7%)

Query: 200 SAALDFSPPGTE---VSALCRGQLPISVTCIADEIGARWDKLSGDVLCPCPGRYLRAGKC 256
           S  +D    GT+   + A+C+   P S  C+    G + +    + +  C   Y   G  
Sbjct: 31  SVDVDECSEGTDDCHIDAICQNT-PKSYKCLCKP-GYKGEGKQCEDIDECENDYYNGGCV 88

Query: 257 AELPNCLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGG 298
            E   C++  G + C C  GF L  DG +C+   E Q   GG
Sbjct: 89  HE---CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGG 127



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 14/37 (37%), Positives = 16/37 (43%)

Query: 262 CLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGG 298
           C D   G  C C  GF L  DG++C    E     GG
Sbjct: 256 CKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGG 292



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 13/40 (32%), Positives = 24/40 (60%), Gaps = 3/40 (7%)

Query: 254 GKCAELPNCLDDLGGFACECATGFELGKDGRSCV-TSGEG 292
           G C ++  C++ +G + C+C +GF L  +  +C+  S EG
Sbjct: 126 GGCQQI--CVNAMGSYECQCHSGFFLSDNQHTCIHRSNEG 163



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 12/31 (38%), Positives = 17/31 (54%), Gaps = 5/31 (16%)

Query: 256 CAELPNCLDDLGGFACECATGFELGKDGRSC 286
           C E P      GG AC+C  GF+L ++ + C
Sbjct: 177 CRETPK-----GGVACDCRPGFDLAQNQKDC 202


>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
          Length = 955

 Score = 37.4 bits (85), Expect = 0.031
 Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 16/81 (19%)

Query: 211 EVSALCRGQLPISVTCIADEIGARWDKLSGDVLCPCPGRYLRAGKCAELPNCLDDLGGFA 270
           EV+ +C    P+  +     +G R   +   V   C G            +C++  GGF 
Sbjct: 120 EVARVC----PVGFSMTETAVGIRCTDIDECVTSSCEG------------HCVNTEGGFV 163

Query: 271 CECATGFELGKDGRSCVTSGE 291
           CEC  G +L  D  SC  + E
Sbjct: 164 CECGPGMQLSADRHSCQDTDE 184



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 60/265 (22%), Positives = 98/265 (36%), Gaps = 47/265 (17%)

Query: 226 CIADEIGARWDKLSGDVLCPC-PGRYLRAGK--CAELPNCL---------DDLGGFACEC 273
           C+            G  +C C PG  L A +  C +   CL         + +G + C C
Sbjct: 146 CVTSSCEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTPCQQRCKNSIGSYKCSC 205

Query: 274 ATGFELGKDGRSCVTSGEGQPTLG------------GTGVPTRRPPATATSPVPQRTWPI 321
            TGF L  +  SCV   E +  L             G+ + T RP            + +
Sbjct: 206 RTGFHLHGNRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRP-----------GFRL 254

Query: 322 RVDEKLGETPLVPEQDNSVTSIPEIPRWGSQSTMSTLQMSLQAESKATITPSGSVISKFN 381
           R D    E    P+   + ++I +  +  S+  +   +    A S     PSG+      
Sbjct: 255 RADRVSCEA--FPKAVLAPSAILQPRQHPSKMLLLLPEAGRPALSPGHSPPSGAPGPPAG 312

Query: 382 STTS---SATPQAFDSSSAVVFIFVSTAVVVLVILTMTVLGLVKLCFHESPSSQPRKESM 438
             T+   S TP+   SS +     +ST ++   + T ++LG ++      P S  + E M
Sbjct: 313 VRTTRLPSPTPRLPTSSPSAPVWLLST-LLATPVPTASLLGNLR------PPSLLQGEVM 365

Query: 439 GPPGLESDPEPAALGSSSAHCTNNG 463
           G P     PE   L +  + C + G
Sbjct: 366 GTPSSPRGPESPRLAAGPSPCWHLG 390


>gi|157384998 low density lipoprotein receptor-related protein 4 [Homo
            sapiens]
          Length = 1905

 Score = 37.0 bits (84), Expect = 0.041
 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 2/40 (5%)

Query: 252  RAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGE 291
            R G C+ L  CL    GF+C C TG +L  DG++C  S E
Sbjct: 1316 RNGGCSHL--CLPRPSGFSCACPTGIQLKGDGKTCDPSPE 1353



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query: 254 GKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSG 290
           G C++   C +  G F C C TG+EL  D RSC   G
Sbjct: 403 GYCSQ--GCTNSEGAFQCWCETGYELRPDRRSCKALG 437



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 242  VLCPCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSC 286
            V  PC    +  G C+ L     +  GF+C C TG  L  DG++C
Sbjct: 1002 VSTPCA---MENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTC 1043


>gi|192447438 protein S, alpha preproprotein [Homo sapiens]
          Length = 676

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 14/63 (22%)

Query: 238 LSGDVLCPCPGRY---LRAGKCAELPNCLDDL---------GGFACEC--ATGFELGKDG 283
           + GD  C CP  Y   L++  C ++  C +++         GG+ C C    GF+L +D 
Sbjct: 220 IPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQ 279

Query: 284 RSC 286
           +SC
Sbjct: 280 KSC 282


>gi|4506115 protein C [Homo sapiens]
          Length = 461

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 5/59 (8%)

Query: 229 DEIGARWDK-LSGDVLCPCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSC 286
           D+  A W K + GD     P  +  A  C     C+D +G F+C+C +G+E    GR C
Sbjct: 77  DDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWE----GRFC 131



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 11/25 (44%), Positives = 16/25 (64%)

Query: 262 CLDDLGGFACECATGFELGKDGRSC 286
           CL+++G   C CA G++LG D   C
Sbjct: 151 CLEEVGWRRCSCAPGYKLGDDLLQC 175


>gi|4557733 latent transforming growth factor beta binding protein 2
            [Homo sapiens]
          Length = 1821

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 27/79 (34%), Positives = 32/79 (40%), Gaps = 6/79 (7%)

Query: 208  PGTEVSALCRGQLPISVTCIADEIGARWDKLSGDVLCPCPGRYLRAGKCAELPNCLDDLG 267
            PGT     C    P S TC+A E G R    S    C      L  G CA    C +  G
Sbjct: 977  PGTCPDGRCVNS-PGSYTCLACEEGYRGQSGS----CVDVNECLTPGVCAH-GKCTNLEG 1030

Query: 268  GFACECATGFELGKDGRSC 286
             F C C  G+E+  D + C
Sbjct: 1031 SFRCSCEQGYEVTSDEKGC 1049



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 27/96 (28%), Positives = 37/96 (38%), Gaps = 7/96 (7%)

Query: 237  KLSGDVLCPCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGE---GQ 293
            +L+   +C      +    CA    CL+  G F C CA GF   + G SC    E     
Sbjct: 1167 QLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTD 1226

Query: 294  PTLGGTGVPTRRP----PATATSPVPQRTWPIRVDE 325
            P +GG  V T         T   P P+    + +DE
Sbjct: 1227 PCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDE 1262



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 17/59 (28%), Positives = 22/59 (37%), Gaps = 12/59 (20%)

Query: 254  GKCAELPNCLDDL------------GGFACECATGFELGKDGRSCVTSGEGQPTLGGTG 300
            G C ++  C +D             G F C C  GFE+   G  CV   E +  L   G
Sbjct: 1299 GDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCG 1357


>gi|46249414 latent transforming growth factor beta binding protein 1
            isoform LTBP-1L [Homo sapiens]
          Length = 1722

 Score = 36.2 bits (82), Expect = 0.070
 Identities = 14/33 (42%), Positives = 17/33 (51%)

Query: 254  GKCAELPNCLDDLGGFACECATGFELGKDGRSC 286
            G C     CL+  G F C C  GF +  DGR+C
Sbjct: 1211 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTC 1243



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 14/39 (35%), Positives = 19/39 (48%)

Query: 262  CLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTG 300
            C +  G F C C  GF+  +DG+ CV   E +   G  G
Sbjct: 1261 CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 1299


>gi|46249412 latent transforming growth factor beta binding protein
           1 isoform LTBP-1S [Homo sapiens]
          Length = 1396

 Score = 36.2 bits (82), Expect = 0.070
 Identities = 14/33 (42%), Positives = 17/33 (51%)

Query: 254 GKCAELPNCLDDLGGFACECATGFELGKDGRSC 286
           G C     CL+  G F C C  GF +  DGR+C
Sbjct: 885 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTC 917



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 14/39 (35%), Positives = 19/39 (48%)

Query: 262 CLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTG 300
           C +  G F C C  GF+  +DG+ CV   E +   G  G
Sbjct: 935 CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 973


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 36.2 bits (82), Expect = 0.070
 Identities = 41/172 (23%), Positives = 63/172 (36%), Gaps = 17/172 (9%)

Query: 294  PTLGGTGVPTRRPPATATSPVPQRTWPIRVDEKLGETPLVPEQDNSVTSIPEIPRWGSQS 353
            PT  GT  PT  P  T T+  P  T         G     P   ++ T++   P      
Sbjct: 1510 PTPTGTQTPTSTPITTTTTVTPTPT-------PTGTQTPTPTPISTTTTVTPTPTPTGTQ 1562

Query: 354  TMSTLQMSLQAESKATITPSG----SVISKFNSTTSSATPQAFDSSSAVVFIFVSTAVVV 409
            T +T  ++       T TP+G    + +    +TT + TP    + S  V    +T  V 
Sbjct: 1563 TPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVT 1622

Query: 410  LV-----ILTMTVLGLVKLCFHESPSSQPRKESMGPPGLESDPEPAALGSSS 456
                     T T++  +      +P+  P   S GPP   S    A L +S+
Sbjct: 1623 ATPTPTGTQTPTMIP-ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSN 1673


>gi|187829730 BCL2 binding component 3 isoform 1 [Homo sapiens]
          Length = 261

 Score = 36.2 bits (82), Expect = 0.070
 Identities = 42/144 (29%), Positives = 55/144 (38%), Gaps = 22/144 (15%)

Query: 245 PCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTGVPTR 304
           P PGR           + L   GG A   A     G  G      G G P  GGT  P  
Sbjct: 122 PAPGR----------SSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGD 171

Query: 305 RPPATATSPVPQRTWPIRVDEKLGET---PLV---PEQDN----SVTSIPEIPRWGSQST 354
           R PA A    PQRT  +R  E  G     PL    P Q +    ++T  P+ PR G+Q  
Sbjct: 172 RGPAAADGGRPQRT--VRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLG 229

Query: 355 MSTLQMSLQAESKATITPSGSVIS 378
             T  + ++      + P  ++ S
Sbjct: 230 ACTRPVDVRDSGGRPLPPPDTLAS 253


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,604,731
Number of Sequences: 37866
Number of extensions: 1291190
Number of successful extensions: 5570
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 96
Number of HSP's that attempted gapping in prelim test: 4809
Number of HSP's gapped (non-prelim): 932
length of query: 490
length of database: 18,247,518
effective HSP length: 106
effective length of query: 384
effective length of database: 14,233,722
effective search space: 5465749248
effective search space used: 5465749248
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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