Guide to the Human Genome
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Name: TPO Sequence: fasta or formatted (876aa) NCBI GI: 28558984
Description:

thyroid peroxidase isoform b

Referenced in:

Superoxide Pathway
Thyroid and Thyroid Hormone Receptor

Other entries for this name:
alt prot [933aa] thyroid peroxidase isoform a
alt prot [889aa] thyroid peroxidase isoform d
alt prot [760aa] thyroid peroxidase isoform e
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.6         84           3
 C cysteine            3.3         29           1
 D aspartate           5.1         45           3
 E glutamate           5.8         51           2
 F phenylalanine       4.1         36           2
 G glycine             7.9         69           3
 H histidine           2.5         22           1
 I isoleucine          3.2         28           2
 K lysine              2.9         25           2
 L leucine             9.7         85           2
 M methionine          1.8         16           1
 N asparagine          3.4         30           2
 P proline             7.2         63           2
 Q glutamine           4.1         36           2
 R arginine            7.3         64           2
 S serine              6.7         59           2
 T threonine           6.2         54           1
 V valine              4.7         41           2
 W tryptophan          2.2         19           2
 Y tyrosine            2.3         20           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   thyroid peroxidase isoform b 
TPO                   0.983   thyroid peroxidase isoform a 
TPO                   0.915   thyroid peroxidase isoform d 
TPO                   0.478   thyroid peroxidase isoform e 
MPO                   0.275   myeloperoxidase 
EPX                   0.268   eosinophil peroxidase 
LPO                   0.237   lactoperoxidase isoform 1 preproprotein 
LPO                   0.234   lactoperoxidase isoform 3 preproprotein 
PXDN                  0.232   peroxidasin 
PXDNL                 0.205   peroxidasin homolog-like 
DUOX1                 0.042   dual oxidase 1 precursor 
DUOX1                 0.042   dual oxidase 1 precursor 
DUOX2                 0.030   dual oxidase 2 precursor 
SVEP1                 0.026   polydom 
LTBP3                 0.022   latent transforming growth factor beta binding prot...
LTBP3                 0.022   latent transforming growth factor beta binding prote...
PTGS2                 0.018   prostaglandin-endoperoxide synthase 2 precursor [Homo...
FBN1                  0.017   fibrillin 1 precursor 
FBN2                  0.015   fibrillin 2 precursor 
FBN3                  0.015   fibrillin 3 precursor 
MEGF6                 0.015   EGF-like-domain, multiple 3 
LRP4                  0.014   low density lipoprotein receptor-related protein 4 ...
SNED1                 0.014   6720455I24Rik homolog 
LTBP4                 0.014   latent transforming growth factor beta binding prot...
LTBP4                 0.014   latent transforming growth factor beta binding prot...
LTBP4                 0.014   latent transforming growth factor beta binding prot...
LTBP1                 0.014   latent transforming growth factor beta binding prote...
LTBP1                 0.014   latent transforming growth factor beta binding prote...
PTGS1                 0.014   prostaglandin-endoperoxide synthase 1 isoform 2 prec...
PTGS1                 0.014   prostaglandin-endoperoxide synthase 1 isoform 1 prec...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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