Guide to the Human Genome
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Name: TPO Sequence: fasta or formatted (933aa) NCBI GI: 28558982
Description:

thyroid peroxidase isoform a

Referenced in:

Superoxide Pathway
Thyroid and Thyroid Hormone Receptor

Other entries for this name:
alt prot [876aa] thyroid peroxidase isoform b
alt prot [889aa] thyroid peroxidase isoform d
alt prot [760aa] thyroid peroxidase isoform e
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.3         87           3
 C cysteine            3.1         29           1
 D aspartate           5.3         49           3
 E glutamate           5.8         54           2
 F phenylalanine       4.0         37           2
 G glycine             7.9         74           3
 H histidine           2.5         23           1
 I isoleucine          3.2         30           2
 K lysine              2.8         26           2
 L leucine            10.5         98           2
 M methionine          1.8         17           1
 N asparagine          3.5         33           2
 P proline             7.1         66           2
 Q glutamine           4.3         40           2
 R arginine            7.4         69           2
 S serine              6.8         63           2
 T threonine           6.0         56           1
 V valine              4.6         43           2
 W tryptophan          2.0         19           2
 Y tyrosine            2.1         20           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   thyroid peroxidase isoform a 
TPO                   0.936   thyroid peroxidase isoform d 
TPO                   0.927   thyroid peroxidase isoform b 
TPO                   0.524   thyroid peroxidase isoform e 
MPO                   0.305   myeloperoxidase 
EPX                   0.299   eosinophil peroxidase 
LPO                   0.270   lactoperoxidase isoform 1 preproprotein 
PXDN                  0.269   peroxidasin 
LPO                   0.266   lactoperoxidase isoform 3 preproprotein 
PXDNL                 0.235   peroxidasin homolog-like 
DUOX1                 0.055   dual oxidase 1 precursor 
DUOX1                 0.055   dual oxidase 1 precursor 
DUOX2                 0.050   dual oxidase 2 precursor 
SVEP1                 0.025   polydom 
LTBP3                 0.020   latent transforming growth factor beta binding prot...
LTBP3                 0.020   latent transforming growth factor beta binding prote...
PTGS2                 0.017   prostaglandin-endoperoxide synthase 2 precursor [Homo...
FBN1                  0.016   fibrillin 1 precursor 
FBN2                  0.014   fibrillin 2 precursor 
FBN3                  0.014   fibrillin 3 precursor 
MEGF6                 0.014   EGF-like-domain, multiple 3 
LRP4                  0.014   low density lipoprotein receptor-related protein 4 ...
SNED1                 0.014   6720455I24Rik homolog 
LTBP4                 0.014   latent transforming growth factor beta binding prot...
LTBP4                 0.014   latent transforming growth factor beta binding prot...
LTBP4                 0.014   latent transforming growth factor beta binding prot...
LTBP1                 0.013   latent transforming growth factor beta binding prote...
LTBP1                 0.013   latent transforming growth factor beta binding prote...
PTGS1                 0.013   prostaglandin-endoperoxide synthase 1 isoform 2 prec...
PTGS1                 0.013   prostaglandin-endoperoxide synthase 1 isoform 1 prec...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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