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Search of human proteins with 253970500
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
(661 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 1413 0.0
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 1395 0.0
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 1391 0.0
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 1043 0.0
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s... 672 0.0
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 458 e-129
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 335 6e-92
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 332 9e-91
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 102 1e-21
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 93 9e-19
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 91 3e-18
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 91 3e-18
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 91 4e-18
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 88 3e-17
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 88 3e-17
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 88 3e-17
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 87 5e-17
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 87 5e-17
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 87 5e-17
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 86 8e-17
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 86 1e-16
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 85 2e-16
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 85 2e-16
gi|62122917 filaggrin family member 2 [Homo sapiens] 84 5e-16
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 83 7e-16
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 82 2e-15
gi|153252068 testes-specific heterogenous nuclear ribonucleoprot... 82 2e-15
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 80 5e-15
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 80 8e-15
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 78 3e-14
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 1413 bits (3658), Expect = 0.0
Identities = 661/661 (100%), Positives = 661/661 (100%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 120
YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA
Sbjct: 61 YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 120
Query: 121 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 180
QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ
Sbjct: 121 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 180
Query: 181 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 240
VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ
Sbjct: 181 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 240
Query: 241 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 300
QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM
Sbjct: 241 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 300
Query: 301 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPD 360
SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPD
Sbjct: 301 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPD 360
Query: 361 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV 420
EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV
Sbjct: 361 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV 420
Query: 421 SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG 480
SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG
Sbjct: 421 SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG 480
Query: 481 GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFA 540
GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFA
Sbjct: 481 GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFA 540
Query: 541 WRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD 600
WRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD
Sbjct: 541 WRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD 600
Query: 601 RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 660
RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP
Sbjct: 601 RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 660
Query: 661 Y 661
Y
Sbjct: 661 Y 661
>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
sapiens]
Length = 655
Score = 1395 bits (3612), Expect = 0.0
Identities = 655/661 (99%), Positives = 655/661 (99%), Gaps = 6/661 (0%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 120
YGQTAYATSYGQPPT GYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA
Sbjct: 61 YGQTAYATSYGQPPT------GYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 114
Query: 121 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 180
QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ
Sbjct: 115 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 174
Query: 181 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 240
VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ
Sbjct: 175 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 234
Query: 241 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 300
QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM
Sbjct: 235 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 294
Query: 301 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPD 360
SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPD
Sbjct: 295 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPD 354
Query: 361 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV 420
EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV
Sbjct: 355 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV 414
Query: 421 SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG 480
SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG
Sbjct: 415 SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG 474
Query: 481 GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFA 540
GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFA
Sbjct: 475 GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFA 534
Query: 541 WRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD 600
WRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD
Sbjct: 535 WRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD 594
Query: 601 RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 660
RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP
Sbjct: 595 RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 654
Query: 661 Y 661
Y
Sbjct: 655 Y 655
>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
Length = 656
Score = 1391 bits (3600), Expect = 0.0
Identities = 655/662 (98%), Positives = 655/662 (98%), Gaps = 7/662 (1%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 120
YGQTAYATSYGQPPT GYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA
Sbjct: 61 YGQTAYATSYGQPPT------GYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 114
Query: 121 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 180
QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ
Sbjct: 115 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 174
Query: 181 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 240
VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ
Sbjct: 175 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 234
Query: 241 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 300
QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM
Sbjct: 235 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 294
Query: 301 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDP 359
SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG AGERGGFNKPGGPMDEGPDLDLGPPVDP
Sbjct: 295 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDP 354
Query: 360 DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 419
DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT
Sbjct: 355 DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 414
Query: 420 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP 479
VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP
Sbjct: 415 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP 474
Query: 480 GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF 539
GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF
Sbjct: 475 GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF 534
Query: 540 AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 599
AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG
Sbjct: 535 AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 594
Query: 600 DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDR 659
DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDR
Sbjct: 595 DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDR 654
Query: 660 PY 661
PY
Sbjct: 655 PY 656
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 1043 bits (2697), Expect = 0.0
Identities = 525/668 (78%), Positives = 541/668 (80%), Gaps = 75/668 (11%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQ QGY+ T AQ T
Sbjct: 1 MASTDYSTYSQAAAQ-----------QGYSAYT---------------------AQPTQG 28
Query: 61 YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTA-TVTTTQASYA 119
Y QT A YGQ Q YGT T + T T A+Y
Sbjct: 29 YAQTTQA--YGQ------------------------QSYGTYGQPTDVSYTQAQTTATYG 62
Query: 120 AQSAYGTQPAYPAYGQQPAA-TAPTRPQDGNKPTETSQPQSSTGGYNQPS--LGYGQSNY 176
Q+AY T +YGQ P T PT PQ ++P + TG Y+ + + Q++Y
Sbjct: 63 -QTAYAT-----SYGQPPTGYTTPTAPQAYSQPVQGY----GTGAYDTTTATVTTTQASY 112
Query: 177 SYPQVPGSYPMQPVTA--PPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQ 234
+ G+ P P P + PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQ
Sbjct: 113 AAQSAYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQ 172
Query: 235 QSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGP 294
QSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGP
Sbjct: 173 QSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGP 232
Query: 295 GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDL 353
GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG AGERGGFNKPGGPMDEGPDLDL
Sbjct: 233 GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDL 292
Query: 354 GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK 413
GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK
Sbjct: 293 GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK 352
Query: 414 PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPP 473
PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPP
Sbjct: 353 PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPP 412
Query: 474 PLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG 533
PLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG
Sbjct: 413 PLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG 472
Query: 534 CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMF 593
CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMF
Sbjct: 473 CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMF 532
Query: 594 RGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHR 653
RGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHR
Sbjct: 533 RGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHR 592
Query: 654 QERRDRPY 661
QERRDRPY
Sbjct: 593 QERRDRPY 600
>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
sapiens]
Length = 354
Score = 672 bits (1734), Expect = 0.0
Identities = 325/331 (98%), Positives = 325/331 (98%), Gaps = 6/331 (1%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 120
YGQTAYATSYGQPPT GYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA
Sbjct: 61 YGQTAYATSYGQPPT------GYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 114
Query: 121 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 180
QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ
Sbjct: 115 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 174
Query: 181 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 240
VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ
Sbjct: 175 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 234
Query: 241 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 300
QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM
Sbjct: 235 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 294
Query: 301 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 331
SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG
Sbjct: 295 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 325
Score = 48.5 bits (114), Expect = 2e-05
Identities = 91/354 (25%), Positives = 129/354 (36%), Gaps = 62/354 (17%)
Query: 188 QPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPS--SYGQQ---SSYGQQS---SYG 239
Q +A + P Y+ T +Y Q SY TYGQP+ SY Q ++YGQ + SYG
Sbjct: 16 QGYSAYTAQPTQGYAQTTQ-AYGQQSYG---TYGQPTDVSYTQAQTTATYGQTAYATSYG 71
Query: 240 QQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQS--------SFRQDHPSSMGVYGQESGGF 291
Q PPT Y T AP YSQ YG + + Q ++ YG + +
Sbjct: 72 Q-PPTGYTTPT-----APQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPA-Y 124
Query: 292 SGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDL 351
G+ + + P G + G + +G G+ ++ P P
Sbjct: 125 PAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQ-SNYSYPQVPGSYPMQP 183
Query: 352 DLGPPVDPDED--SDNSAIYVQG-LNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLD 408
PP P S Y Q + T + + +Q + + QP
Sbjct: 184 VTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQP------- 236
Query: 409 KETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREG 468
T P T SY P+ + Q S + ++ +SM G+ +E
Sbjct: 237 -PTSYPP--QTGSYSQAPSQYSQ---------QSSSYGQQSSFRQDHPSSM--GVYGQES 282
Query: 469 RGMPPPLRGGPGGPGGPGGPMGRMGGRGG-DRGGFPPRGPRGSRGNPSGGGNVQ 521
G GPG GP R GRGG DRGG RG RG GG +Q
Sbjct: 283 GGF-----SGPGENRSMSGPDNRGRGRGGFDRGGM----SRGGRGGGRGGMGLQ 327
Score = 42.7 bits (99), Expect = 0.001
Identities = 24/43 (55%), Positives = 25/43 (58%), Gaps = 4/43 (9%)
Query: 561 FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGG 603
F PG +R GP GRGG DR GGM RGGRGG RGG
Sbjct: 285 FSGPGENRSMSGPDNRGRGRGG-FDR---GGMSRGGRGGGRGG 323
Score = 36.2 bits (82), Expect = 0.099
Identities = 22/47 (46%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 571 GGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF-RGGRGMDRGGFG 616
G G G G GP RG G DRGG RGGRG RGG G
Sbjct: 279 GQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 325
Score = 30.8 bits (68), Expect = 4.2
Identities = 24/52 (46%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 595 GGRGGDRGGFRGGRGMDRGGFGGGRRG-GPGGPPGPLMEQMGGRRGGRGGPG 645
G G + GGF G G +R G RG G GG M + GGR GGRGG G
Sbjct: 276 GVYGQESGGF-SGPGENRSMSGPDNRGRGRGGFDRGGMSR-GGRGGGRGGMG 325
Score = 30.4 bits (67), Expect = 5.4
Identities = 21/39 (53%), Positives = 21/39 (53%), Gaps = 3/39 (7%)
Query: 588 GPGGMFRGGRGGDRGGFRGGRGMDRGGFG-GGRRGGPGG 625
GPG R G D G RG G DRGG GGR GG GG
Sbjct: 287 GPGEN-RSMSGPDNRG-RGRGGFDRGGMSRGGRGGGRGG 323
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 458 bits (1178), Expect = e-129
Identities = 297/666 (44%), Positives = 359/666 (53%), Gaps = 145/666 (21%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59
MAS DY+ A Q Y AY QP QGY+Q ++Q YGQQSY Y Q TD T+
Sbjct: 1 MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48
Query: 60 TYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYA 119
YGQ++Y+ SYGQ +TGY T + PQ Y TG Y + S +
Sbjct: 49 GYGQSSYS-SYGQ-----SQNTGYGTQSTPQGYGS------TGGYGS----------SQS 86
Query: 120 AQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYP 179
+QS+YG Q +YP YGQQPA P S++G Y S S+Y P
Sbjct: 87 SQSSYGQQSSYPGYGQQPA------------------PSSTSGSYGSSS---QSSSYGQP 125
Query: 180 QVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYG 239
Q GSY QP SY Q SY QQ +Y P YGQQ+ Y S G
Sbjct: 126 Q-SGSYSQQP----------SYGG------QQQSYGQQQSYNPPQGYGQQNQYNSSSGGG 168
Query: 240 QQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRS 299
G+Y Q S S S G + Q G YGQ+ G G G +
Sbjct: 169 GGGGGG-----GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGG 223
Query: 300 MSGPDNRG--RGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPV 357
G G R GG++ G RGG GGRGGMG +RGGFNK GGP D+G D
Sbjct: 224 GGGGGGGGYNRSSGGYEPRG--RGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHD----- 276
Query: 358 DPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGD 417
++SDN+ I+VQGL ++VT++ +AD+FKQ G++K NK+TGQPMI++Y D+ETGK KG+
Sbjct: 277 SEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGE 336
Query: 418 ATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRG 477
ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++ N RGG R GRG RG
Sbjct: 337 ATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGRG-----RG 389
Query: 478 GPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQ 537
GP G GG GG G GG RGGFP G GGG Q RAGDW+CPNP C N
Sbjct: 390 GPMGRGGYGGG----GSGGGGRGGFPSGG---------GGGGGQQRAGDWKCPNPTCENM 436
Query: 538 NFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGR 597
NF+WR ECNQCKAPKP+G PG GGPGG G G G RGGR
Sbjct: 437 NFSWRNECNQCKAPKPDG--------PG-----GGPGGSHMG-------GNYGDDRRGGR 476
Query: 598 GG-DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQE 655
GG DRGG+R GRG DRGGF GGR GG RGG GPGKMD +GEHRQ+
Sbjct: 477 GGYDRGGYR-GRGGDRGGFRGGRGGGD--------------RGG-FGPGKMDSRGEHRQD 520
Query: 656 RRDRPY 661
RR+RPY
Sbjct: 521 RRERPY 526
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 335 bits (860), Expect = 6e-92
Identities = 228/553 (41%), Positives = 283/553 (51%), Gaps = 95/553 (17%)
Query: 125 GTQPAYPAYGQ---QPAATAPTRPQDGNKPTETSQPQSSTG--GYNQPSLGYGQSNYSYP 179
G Q +Y YG Q A + T++S Q+ +G Y Q GY QS Y
Sbjct: 12 GEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYE 71
Query: 180 -QVPGSYPMQPVTAPPSYPPTSYSSTQ---PTSYDQSSYSQQNTYGQPSSYGQ-QSSYGQ 234
Q SY QP S +Q SYDQ Y QQ++Y Q S Y Q Q SY +
Sbjct: 72 NQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDE 131
Query: 235 QSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGP 294
QS+Y QQ SYSQ Y Q +Y + QD + YG+++ G+ G
Sbjct: 132 QSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDDRRDVSRYGEDNRGYGG- 179
Query: 295 GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLG 354
S G GRGRGG+D+ G RG G GG +RGGF GG D GP D
Sbjct: 180 ----SQGG----GRGRGGYDKDG--RGPMTGSSGG----DRGGFKNFGGHRDYGPRTDAD 225
Query: 355 PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP 414
D +SDN+ I+VQGL + V+ D + +FFKQ G++K NK+TG+PMI++Y DK+TGKP
Sbjct: 226 SESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKP 282
Query: 415 KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPP 474
KG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P MRGG
Sbjct: 283 KGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF--MRGG------------ 328
Query: 475 LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC 534
G GG GR G RG RGGF RG G+P ++GDW CPNP C
Sbjct: 329 --------GSGGGRRGRGGYRG--RGGFQGRG-----GDP--------KSGDWVCPNPSC 365
Query: 535 GNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRGRGGPGGMRGGRGGLMDRG 587
GN NFA R CNQC P+PE P + G RGRGG GG RGG GG G
Sbjct: 366 GNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGG 425
Query: 588 GPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 643
G GG GG GDR G GG G DR GG+GG R GG GG G GG G RGG
Sbjct: 426 GYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRG------GGYGGDRGG 477
Query: 644 PGKMDKGEHRQER 656
D+G + +R
Sbjct: 478 GYGGDRGGYGGDR 490
Score = 81.3 bits (199), Expect = 3e-15
Identities = 75/201 (37%), Positives = 82/201 (40%), Gaps = 61/201 (30%)
Query: 461 GGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNV 520
GG G G GG GG G GG G GG GGDRGG G RG G GG
Sbjct: 453 GGYGGDRGGGYGGDRGGGYGGDRG-GGYGGDRGGYGGDRGG-GYGGDRGGYGGDRGG--- 507
Query: 521 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 580
GD G G + GGDR RGG GG RGG
Sbjct: 508 --YGGD----RGGYGGDRGGY-----------------------GGDRSRGGYGGDRGGG 538
Query: 581 GGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGG 640
G GG GG GGDR G GG G DRGG GG RGG GG +MGGR
Sbjct: 539 SGY------GGDRSGGYGGDRSG--GGYGGDRGGGYGGDRGGYGG-------KMGGR--- 580
Query: 641 RGGPGKMDKGEHRQERRDRPY 661
++R ++R+RPY
Sbjct: 581 ---------NDYRNDQRNRPY 592
Score = 54.7 bits (130), Expect = 3e-07
Identities = 55/164 (33%), Positives = 62/164 (37%), Gaps = 55/164 (33%)
Query: 460 RGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGN 519
RGG G G RGG GG G G G GG GGDRGG+ RG G GGG+
Sbjct: 483 RGGYGGDRGGGYGGD-RGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGGDRGGGS 539
Query: 520 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGG 579
G+ GGDR GG GG R G
Sbjct: 540 -----------------------------------GY--------GGDRS-GGYGGDRSG 555
Query: 580 RGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGP 623
GG GG GG GGDRGG+ GG+ R + +R P
Sbjct: 556 -------GGYGGDRGGGYGGDRGGY-GGKMGGRNDYRNDQRNRP 591
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/101 (37%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
Query: 233 GQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYG-QQSSFRQDHPSSMGVYGQESGGF 291
G + YG Y G Y Y YG + + D S G YG + GG
Sbjct: 481 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR--SRGGYGGDRGGG 538
Query: 292 SGPGENRSMS-GPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 331
SG G +RS G D G G GG DRGG G RGG G MG
Sbjct: 539 SGYGGDRSGGYGGDRSGGGYGG-DRGGGYGGDRGGYGGKMG 578
Score = 48.5 bits (114), Expect = 2e-05
Identities = 38/115 (33%), Positives = 43/115 (37%), Gaps = 9/115 (7%)
Query: 238 YGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGE 296
YG Y G Y Y YG R + G YG + GG+ G
Sbjct: 471 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD---RGGYGGDRGGYGGDRGGYGGDRS 527
Query: 297 NRSMSGPDNRGRGRGGFDRGG----MSRGGRGGGRGGMGAGERGGF-NKPGGPMD 346
G G G GG GG S GG GG RGG G+RGG+ K GG D
Sbjct: 528 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRND 582
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/87 (42%), Positives = 41/87 (47%), Gaps = 10/87 (11%)
Query: 260 YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGM- 318
Y SS G S R S G G SGG G G +R +RG G GG DRGG
Sbjct: 427 YGGDRSSGGGYSGDR----SGGGYGGDRSGG--GYGGDRGGGYGGDRGGGYGG-DRGGGY 479
Query: 319 --SRGGRGGGRGGMGAGERGGFNKPGG 343
RGG GG RGG G+RGG+ G
Sbjct: 480 GGDRGGYGGDRGGGYGGDRGGYGGDRG 506
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/153 (27%), Positives = 58/153 (37%), Gaps = 17/153 (11%)
Query: 215 SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYS----QQSSSYGQQ 270
S +YGQ S G+Q SY S+YG P + Y QA YS SSYGQ
Sbjct: 2 SDSGSYGQ--SGGEQQSY---STYGN-------PGSQGYGQASQSYSGYGQTTDSSYGQN 49
Query: 271 SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGM 330
S + S Y Q GG+ ++ P N + + G S+GGR
Sbjct: 50 YSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSG-SQGGRAPSYDQP 108
Query: 331 GAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDS 363
G++ +++ G D D DS
Sbjct: 109 DYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDS 141
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/67 (46%), Positives = 36/67 (53%), Gaps = 7/67 (10%)
Query: 280 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR---GGRGGGRGGMGAGERG 336
S G YG + GG G G +R +RG G GG DRGG GG GG RGG G G+RG
Sbjct: 451 SGGGYGGDRGG--GYGGDRGGGYGGDRGGGYGG-DRGGYGGDRGGGYGGDRGGYG-GDRG 506
Query: 337 GFNKPGG 343
G+ G
Sbjct: 507 GYGGDRG 513
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/82 (41%), Positives = 38/82 (46%), Gaps = 17/82 (20%)
Query: 282 GVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMS--RGGRGGGRGGMGA-- 332
G YG + GG G G +R G D G RG G DRGG RGG GG RGG G
Sbjct: 469 GGYGGDRGG--GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR 526
Query: 333 ------GERGGFNKPGGPMDEG 348
G+RGG + GG G
Sbjct: 527 SRGGYGGDRGGGSGYGGDRSGG 548
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/71 (43%), Positives = 35/71 (49%), Gaps = 9/71 (12%)
Query: 280 SMGVYGQE---SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGG----RGGMGA 332
S G YG + GG+SG G D G G GG DRGG G RGGG RGG
Sbjct: 423 SGGGYGGDRSSGGGYSGDRSGGGYGG-DRSGGGYGG-DRGGGYGGDRGGGYGGDRGGGYG 480
Query: 333 GERGGFNKPGG 343
G+RGG+ G
Sbjct: 481 GDRGGYGGDRG 491
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 332 bits (850), Expect = 9e-91
Identities = 229/558 (41%), Positives = 282/558 (50%), Gaps = 100/558 (17%)
Query: 115 QASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQS 174
Q SY S YG P YGQ ++ G T S + GY+ Y QS
Sbjct: 14 QQSY---STYGN-PGSQGYGQA------SQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63
Query: 175 NYSYP-QVPGSYPMQPVTAPPSYPPTSYSSTQ---PTSYDQSSYSQQNTYGQPSSYGQ-Q 229
Y Q SY QP S +Q SYDQ Y QQ++Y Q S Y Q Q
Sbjct: 64 YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQ 123
Query: 230 SSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG 289
SY +QS+Y QQ SYSQ Y Q +Y + QD + YG+++
Sbjct: 124 GSYDEQSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDDRRDVSRYGEDNR 172
Query: 290 GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGP 349
G+ G S G GRGRGG+D+ G RG G GG +RGGF GG D GP
Sbjct: 173 GYGG-----SQGG----GRGRGGYDKDG--RGPMTGSSGG----DRGGFKNFGGHRDYGP 217
Query: 350 DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK 409
D D +SDN+ I+VQGL + V+ D + +FFKQ G++K NK+TG+PMI++Y DK
Sbjct: 218 RTDADSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDK 274
Query: 410 ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGR 469
+TGKPKG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P MRGG
Sbjct: 275 DTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF--MRGG------- 325
Query: 470 GMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQC 529
G GG GR G RG RGGF RG G+P ++GDW C
Sbjct: 326 -------------GSGGGRRGRGGYRG--RGGFQGRG-----GDP--------KSGDWVC 357
Query: 530 PNPGCGNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRGRGGPGGMRGGRGG 582
PNP CGN NFA R CNQC P+PE P + G RGRGG GG RGG GG
Sbjct: 358 PNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGG 417
Query: 583 LMDRGGPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPPGPLMEQMGGRR 638
GG GG GG GDR G GG G DR GG+GG R GG GG G GG
Sbjct: 418 DRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRG------GGYG 469
Query: 639 GGRGGPGKMDKGEHRQER 656
G RGG D+G + +R
Sbjct: 470 GDRGGGYGGDRGGYGGDR 487
Score = 81.3 bits (199), Expect = 3e-15
Identities = 75/201 (37%), Positives = 82/201 (40%), Gaps = 61/201 (30%)
Query: 461 GGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNV 520
GG G G GG GG G GG G GG GGDRGG G RG G GG
Sbjct: 450 GGYGGDRGGGYGGDRGGGYGGDRG-GGYGGDRGGYGGDRGG-GYGGDRGGYGGDRGG--- 504
Query: 521 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 580
GD G G + GGDR RGG GG RGG
Sbjct: 505 --YGGD----RGGYGGDRGGY-----------------------GGDRSRGGYGGDRGGG 535
Query: 581 GGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGG 640
G GG GG GGDR G GG G DRGG GG RGG GG +MGGR
Sbjct: 536 SGY------GGDRSGGYGGDRSG--GGYGGDRGGGYGGDRGGYGG-------KMGGR--- 577
Query: 641 RGGPGKMDKGEHRQERRDRPY 661
++R ++R+RPY
Sbjct: 578 ---------NDYRNDQRNRPY 589
Score = 54.7 bits (130), Expect = 3e-07
Identities = 55/164 (33%), Positives = 62/164 (37%), Gaps = 55/164 (33%)
Query: 460 RGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGN 519
RGG G G RGG GG G G G GG GGDRGG+ RG G GGG+
Sbjct: 480 RGGYGGDRGGGYGGD-RGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGGDRGGGS 536
Query: 520 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGG 579
G+ GGDR GG GG R G
Sbjct: 537 -----------------------------------GY--------GGDRS-GGYGGDRSG 552
Query: 580 RGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGP 623
GG GG GG GGDRGG+ GG+ R + +R P
Sbjct: 553 -------GGYGGDRGGGYGGDRGGY-GGKMGGRNDYRNDQRNRP 588
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/101 (37%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
Query: 233 GQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYG-QQSSFRQDHPSSMGVYGQESGGF 291
G + YG Y G Y Y YG + + D S G YG + GG
Sbjct: 478 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR--SRGGYGGDRGGG 535
Query: 292 SGPGENRSMS-GPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 331
SG G +RS G D G G GG DRGG G RGG G MG
Sbjct: 536 SGYGGDRSGGYGGDRSGGGYGG-DRGGGYGGDRGGYGGKMG 575
Score = 48.5 bits (114), Expect = 2e-05
Identities = 38/115 (33%), Positives = 43/115 (37%), Gaps = 9/115 (7%)
Query: 238 YGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGE 296
YG Y G Y Y YG R + G YG + GG+ G
Sbjct: 468 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD---RGGYGGDRGGYGGDRGGYGGDRS 524
Query: 297 NRSMSGPDNRGRGRGGFDRGG----MSRGGRGGGRGGMGAGERGGF-NKPGGPMD 346
G G G GG GG S GG GG RGG G+RGG+ K GG D
Sbjct: 525 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRND 579
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/87 (42%), Positives = 41/87 (47%), Gaps = 10/87 (11%)
Query: 260 YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGM- 318
Y SS G S R S G G SGG G G +R +RG G GG DRGG
Sbjct: 424 YGGDRSSGGGYSGDR----SGGGYGGDRSGG--GYGGDRGGGYGGDRGGGYGG-DRGGGY 476
Query: 319 --SRGGRGGGRGGMGAGERGGFNKPGG 343
RGG GG RGG G+RGG+ G
Sbjct: 477 GGDRGGYGGDRGGGYGGDRGGYGGDRG 503
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/67 (46%), Positives = 36/67 (53%), Gaps = 7/67 (10%)
Query: 280 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR---GGRGGGRGGMGAGERG 336
S G YG + GG G G +R +RG G GG DRGG GG GG RGG G G+RG
Sbjct: 448 SGGGYGGDRGG--GYGGDRGGGYGGDRGGGYGG-DRGGYGGDRGGGYGGDRGGYG-GDRG 503
Query: 337 GFNKPGG 343
G+ G
Sbjct: 504 GYGGDRG 510
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/82 (41%), Positives = 38/82 (46%), Gaps = 17/82 (20%)
Query: 282 GVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMS--RGGRGGGRGGMGA-- 332
G YG + GG G G +R G D G RG G DRGG RGG GG RGG G
Sbjct: 466 GGYGGDRGG--GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR 523
Query: 333 ------GERGGFNKPGGPMDEG 348
G+RGG + GG G
Sbjct: 524 SRGGYGGDRGGGSGYGGDRSGG 545
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/71 (43%), Positives = 35/71 (49%), Gaps = 9/71 (12%)
Query: 280 SMGVYGQE---SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGG----RGGMGA 332
S G YG + GG+SG G D G G GG DRGG G RGGG RGG
Sbjct: 420 SGGGYGGDRSSGGGYSGDRSGGGYGG-DRSGGGYGG-DRGGGYGGDRGGGYGGDRGGGYG 477
Query: 333 GERGGFNKPGG 343
G+RGG+ G
Sbjct: 478 GDRGGYGGDRG 488
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 102 bits (254), Expect = 1e-21
Identities = 143/492 (29%), Positives = 171/492 (34%), Gaps = 119/492 (24%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPS---QYSQQSSSYGQQSSFRQDH 277
G P + G + + G + S GQ P PP T + +P + S + ++
Sbjct: 312 GLPGAAGARGNDGARGSDGQPGPPG-PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE 370
Query: 278 PSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-GERG 336
P G G + G PG N S G G G M G G G GA G RG
Sbjct: 371 PGPQGHAGAQ-GPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRG 429
Query: 337 GFNKPG--------GPMDEGPDLDL-GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK 387
G +PG GP E + + G P ED + + G N
Sbjct: 430 GAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGAN------------- 476
Query: 388 QCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV 447
G+ G P P G + E P +
Sbjct: 477 --GLPGAAGERGAPGFR--------GPAGPNGIPGEKGPAGE------------------ 508
Query: 448 SLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMG--GRGGD 498
R P RG G P R+G P +RG PG PGGPG GP G G GR G
Sbjct: 509 ---RGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGP 565
Query: 499 RGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC-GNQNFAWRTECNQCKAPKPEGFL 557
G PRG G G P GN + + PG G Q P G
Sbjct: 566 PGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG-----------PPGKNGET 614
Query: 558 PPPFPP----PGGDRGRGGPGGMRG-----GRGGLMDR----------------GGPGGM 592
P PP PGGD+G GP G +G G GG G PGG
Sbjct: 615 GPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGK 674
Query: 593 FRGGRGGDRG--------GFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGG 640
G G+RG G RGG G G GG GP GPPG P ++ M G RGG
Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAG-PPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733
Query: 641 RGGPG-KMDKGE 651
G PG K DKGE
Sbjct: 734 LGSPGPKGDKGE 745
Score = 100 bits (248), Expect = 6e-21
Identities = 129/433 (29%), Positives = 158/433 (36%), Gaps = 68/433 (15%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G P G G G + P + G P S G S + P S
Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDG-VPGGPGMRGMPGSPGGPGSDGKPGPPGS 556
Query: 281 MGVYGQESG-GFSGP-GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGF 338
G G+ G SGP G+ M P +G G + G GG GG G G
Sbjct: 557 QGESGRPGPPGPSGPRGQPGVMGFPGPKGND------GAPGKNGERGGPGGPGPQGPPGK 610
Query: 339 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 398
N GP +GP GP D + +QGL + G N +
Sbjct: 611 NGETGP--QGPPGPTGPGGDKGDTGPPGPQGLQGLPGT------------GGPPGENGKP 656
Query: 399 GQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNS 458
G+P PKGDA P A GK G+ + PP
Sbjct: 657 GEP-----------GPKGDA-----GAPGAPG------GKGDAGAP-----GERGPP--G 687
Query: 459 MRGGLPPREGRGMPPPLRG-GPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPS 515
+ G R G G P P G G GP GP G G G G G+RGG GP+G +G P
Sbjct: 688 LAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPG 747
Query: 516 GGG--NVQHRAGDWQCPNPGCGNQNFAWRT-ECNQCKAPKPEGFLPPPFPPPGGDRGRGG 572
G G V + G + P G A + + + AP G P P G+RG G
Sbjct: 748 GPGADGVPGKDGP-RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSP--GERGETG 804
Query: 573 PGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLME 632
P G G G G PGG G G++G GG G GG GP GPPGP +
Sbjct: 805 PPGPAGFPGAPGQNGEPGGKGERGAPGEKG--EGGPPGVAGPPGG---SGPAGPPGP--Q 857
Query: 633 QMGGRRGGRGGPG 645
+ G RG GGPG
Sbjct: 858 GVKGERGSPGGPG 870
Score = 98.2 bits (243), Expect = 2e-20
Identities = 151/550 (27%), Positives = 179/550 (32%), Gaps = 83/550 (15%)
Query: 140 TAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPT 199
TAPTRP +G P Q G P + + P PGS P P PP +
Sbjct: 93 TAPTRPPNGQGP------QGPKGDPGPPGIPGRNGDPGIPGQPGS-PGSP--GPPGICES 143
Query: 200 SYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPS 258
+ Q S SY ++ G G G + +P GS Q P
Sbjct: 144 CPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPP 203
Query: 259 QYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFD--R 315
Q+ G PS ESG PGE P +G G GF +
Sbjct: 204 GEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMK 263
Query: 316 GGMSRGGRGGGRGGMGA-GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN 374
G GR G +G GA G +G PG GP G P + A +G N
Sbjct: 264 GHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARG-N 322
Query: 375 DSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEW 434
D D GQP G P T + P AK V
Sbjct: 323 DGARGSD-----------------GQP----------GPPGPPGTAGFPGSPGAKGEVGP 355
Query: 435 FDGKDFQGSK-------LKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG-----GP 482
G+ + + PP G P +G P + G PG GP
Sbjct: 356 AGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGP 415
Query: 483 GGPGGPMGRMG--------GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC 534
GP G G G G+ G +G PRG RG G P G D PG
Sbjct: 416 PGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGA 475
Query: 535 -GNQNFAWRTECNQCKAPK-PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGM 592
G A + P P G P P G+RG GP G RG G G PGG
Sbjct: 476 NGLPGAAGERGAPGFRGPAGPNGI--PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533
Query: 593 -FRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ--MG-------------- 635
RG G G G+ G G R GP GP GP + MG
Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593
Query: 636 GRRGGRGGPG 645
G RGG GGPG
Sbjct: 594 GERGGPGGPG 603
Score = 84.7 bits (208), Expect = 2e-16
Identities = 125/444 (28%), Positives = 153/444 (34%), Gaps = 63/444 (14%)
Query: 221 GQPSSYGQQSS------YGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFR 274
GQP G+ + G + S G++ T PP + AP Q + + +
Sbjct: 774 GQPGDKGEGGAPGLPGIAGPRGSPGERGETG-PPGPAGFPGAPGQNGEPGGKGERGAPGE 832
Query: 275 QDHPSSMGVYGQESG-GFSGP-------GENRSMSGPDNRG----RGRGGFDRGGMSRGG 322
+ GV G G G +GP GE S GP G RG G G G
Sbjct: 833 KGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPG-PPGSNGNPG 891
Query: 323 RGGGRGGMGA----GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 378
G G G G G PG P GP D G P E A G +
Sbjct: 892 PPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAG---QPGEKGSPGAQGPPGAPGPLG 948
Query: 379 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAK-----AAVE 433
+ + G M G P + E+GKP + PP + A
Sbjct: 949 IAGITGARGLAGPPGMPGPRGSPGPQ-GVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007
Query: 434 WFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGR 491
G+D G+ L P + GG R G P G PG PG PG GP+G
Sbjct: 1008 GEPGRD--GNPGSDGL----PGRDGSPGGKGDRGENGSP----GAPGAPGHPGPPGPVGP 1057
Query: 492 MGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAP 551
G+ GDRG P GP G+ G AG P P + E
Sbjct: 1058 -AGKSGDRGESGPAGPAGAPGP----------AGSRGAPGPQGPRGDKGETGERGAAGIK 1106
Query: 552 KPEGFL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFR 605
GF P P P G +G G G G RG + G PG G G G G R
Sbjct: 1107 GHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPR 1166
Query: 606 GGRGMDRGGFGGGRRGGPGGPPGP 629
G RG +RG G G GPPGP
Sbjct: 1167 GNRG-ERGSEGSPGHPGQPGPPGP 1189
Score = 81.6 bits (200), Expect = 2e-15
Identities = 141/539 (26%), Positives = 161/539 (29%), Gaps = 110/539 (20%)
Query: 162 GGYNQPSLGYGQSNYSYPQVPGSY-----PMQPVTAPPSYPPTSYSSTQPTSYDQS--SY 214
G P G + P PGS P P + P P P D +
Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593
Query: 215 SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFR 274
++ G P G G+ G PT G Q Q G
Sbjct: 594 GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG-E 652
Query: 275 QDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG----RGRGGFDRGGMSRGGRGGGRGGM 330
P G G ++G PG P RG G G RGG G GG+G
Sbjct: 653 NGKPGEPGPKG-DAGAPGAPGGKGDAGAPGERGPPGLAGAPGL-RGGAGPPGPEGGKGAA 710
Query: 331 GA----------------GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN 374
G GERGG PG P D G P P D +G
Sbjct: 711 GPPGPPGAAGTPGLQGMPGERGGLGSPG------PKGDKGEPGGPGADGVPGKDGPRGPT 764
Query: 375 DSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEW 434
+ A Q G G P I P+G E P A
Sbjct: 765 GPIGPPGPAG---QPGDKGEGGAPGLPGI--------AGPRGSPGERGETGPPGPAG--- 810
Query: 435 FDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG--PGGPGGPMGRM 492
F G Q + P G P +G G PP + G PGG P GP GP G
Sbjct: 811 FPGAPGQNGE----------PGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVK 860
Query: 493 GGRGGDRG----GFPPR----GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTE 544
G RG G GFP GP GS GNP G P+ G
Sbjct: 861 GERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG-----------PSGSPGKDG------ 903
Query: 545 CNQCKAPKPEGFLPPPFPPP-GGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 602
P P G P P G +G G G +G G G PG + G G RG
Sbjct: 904 -----PPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGL 958
Query: 603 ----GFRGGRGMDRGGFGGGRRGGPG--------GPPGPL----MEQMGGRRGGRGGPG 645
G G RG G G PG GPPGP + G G G PG
Sbjct: 959 AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPG 1017
Score = 80.5 bits (197), Expect = 5e-15
Identities = 147/553 (26%), Positives = 176/553 (31%), Gaps = 125/553 (22%)
Query: 181 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY----------SQQNTYGQPSSYGQQS 230
VPG M+ + P P + P S +S Q G P G
Sbjct: 529 VPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDG 588
Query: 231 SYGQQSSYG------QQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVY 284
+ G+ G Q P +TG Q P + G P G+
Sbjct: 589 APGKNGERGGPGGPGPQGPPGKNGETGP--QGPPGPTGPGGDKGDTGP-----PGPQGLQ 641
Query: 285 GQESGGFSGPGENRSMSGPDNRG-------------------RGRGGFD-----RGGMSR 320
G G PGEN P +G RG G RGG
Sbjct: 642 GLPGTG-GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGP 700
Query: 321 GGRGGGRGGMG----------------AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSD 364
G GG+G G GERGG P GP D G P P D
Sbjct: 701 PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSP------GPKGDKGEPGGPGADGV 754
Query: 365 NSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYED 424
+G + A Q G G P I P+G E
Sbjct: 755 PGKDGPRGPTGPIGPPGPAG---QPGDKGEGGAPGLPGI--------AGPRGSPGERGET 803
Query: 425 PPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG--GP 482
P A F G Q +P RG P +G G PP + G PG GP
Sbjct: 804 GPPGPAG---FPGAPGQNG---------EPGGKGERGA-PGEKGEGGPPGVAGPPGGSGP 850
Query: 483 GGPGGPMGRMGGRGGDRG----GFPPR----GPRGSRGNPS--------GGGNVQHRAGD 526
GP GP G G RG G GFP GP GS GNP G AG+
Sbjct: 851 AGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGN 910
Query: 527 WQCP-NPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPP------GGDRGRGGPGGMRGG 579
P +PG + + +P +G PP P P G RG GP GM G
Sbjct: 911 TGAPGSPGVSGPK-GDAGQPGEKGSPGAQG--PPGAPGPLGIAGITGARGLAGPPGMPGP 967
Query: 580 RGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRG 639
RG +G G + G G G RG G G G PG P + + GR G
Sbjct: 968 RGSPGPQGVKGESGKPGANG-LSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDG 1026
Query: 640 GRGGPGKMDKGEH 652
GG G D+GE+
Sbjct: 1027 SPGGKG--DRGEN 1037
Score = 65.9 bits (159), Expect = 1e-10
Identities = 65/221 (29%), Positives = 80/221 (36%), Gaps = 65/221 (29%)
Query: 454 PPMNSMRGGLPPREGRGMPP--PLRGGPGGPGGPGGPMGRMG-----------GRGGDRG 500
PP S G P G PP P + GP GP GP G +G G GR G+RG
Sbjct: 184 PPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERG 243
Query: 501 GFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP 560
P G +G G P G HR D +
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGR-------------------------------- 271
Query: 561 FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGF 615
G++G G G++G G + G PG M G G+RG G G RG D G
Sbjct: 272 ----NGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGND-GAR 326
Query: 616 GGGRRGGPGGPPGPL--------MEQMG--GRRGGRGGPGK 646
G + GP GPPG ++G G G G PG+
Sbjct: 327 GSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQ 367
Score = 63.2 bits (152), Expect = 8e-10
Identities = 81/298 (27%), Positives = 102/298 (34%), Gaps = 83/298 (27%)
Query: 414 PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPP 473
P G+ PPTA +G+ QG K PP G+P R G P
Sbjct: 80 PFGECCAVCPQPPTAPTRPP--NGQGPQGPK-----GDPGPP------GIPGRNG---DP 123
Query: 474 PLRGGPGGPGGPGGP---------------------------MGRMGGRGGDRGGFPPRG 506
+ G PG PG PG P +G + G G G P G
Sbjct: 124 GIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPG 183
Query: 507 PRGSRGNPSGGGNVQH--------RAGDWQCPNP--GCGNQNFAWRT-ECNQCKAPKPEG 555
P G+ G+P G+ + +AG P P G A + E + P G
Sbjct: 184 PPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERG 243
Query: 556 FLPPP-------------------FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 596
PP F G++G G G++G G + G PG M G
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRG 303
Query: 597 RGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGPG 645
G+RG G G RG D G G + GP GPPG P G G G PG
Sbjct: 304 APGERGRPGLPGAAGARGND-GARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPG 360
Score = 61.6 bits (148), Expect = 2e-09
Identities = 69/218 (31%), Positives = 85/218 (38%), Gaps = 59/218 (27%)
Query: 473 PPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP 532
PP GP GP G GP G + GR GD G P G GS G+P G + CP
Sbjct: 98 PPNGQGPQGPKGDPGPPG-IPGRNGDPG-IP--GQPGSPGSPGPPGICE------SCPT- 146
Query: 533 GCGNQNFAWRTECNQCKA----------PKPEGFLPPPFPP----------------PGG 566
G QN++ + + K+ P P G PP PP P G
Sbjct: 147 --GPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG 204
Query: 567 DRGRGGPGGMRGGRGGLMDRGGPGGMF----RGGRGGDRG-----GFRGGRGMDRGGFGG 617
+ G+ GP G G G + GP G R GR G+RG G +G G+ GF G
Sbjct: 205 EPGQAGPSGPPGPPGAI-GPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIP--GFPG 261
Query: 618 --------GRRGGPGGPPGPLMEQMGGRRGGRGGPGKM 647
GR G G P ++ G G G PG M
Sbjct: 262 MKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPM 299
Score = 40.0 bits (92), Expect = 0.007
Identities = 40/135 (29%), Positives = 45/135 (33%), Gaps = 28/135 (20%)
Query: 529 CPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGG 588
CPNP + C C P PP P G +G GP G+ G G D G
Sbjct: 74 CPNP-----EIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNG---DPGI 125
Query: 589 PGGMFRGGRGGDRG-----------------GFRGGRGMDRGGFGG-GRRGGPGGPPGPL 630
PG G G G + G+ GG G GP GPPGP
Sbjct: 126 PGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP- 184
Query: 631 MEQMGGRRGGRGGPG 645
G G G PG
Sbjct: 185 -PGTSGHPGSPGSPG 198
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 92.8 bits (229), Expect = 9e-19
Identities = 147/552 (26%), Positives = 192/552 (34%), Gaps = 91/552 (16%)
Query: 117 SYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNY 176
++A Q +YG P P+ P+ P PQ G +P G+
Sbjct: 158 NFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEP----GEPGA 213
Query: 177 SYPQVPGSYPMQPVTAPPSYPPTSYSSTQP-------TSYDQSSYSQQNTYGQPSSYGQQ 229
S P P P PP + +P Q + T G P G +
Sbjct: 214 SGPMGPRGPP-----GPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHR 268
Query: 230 SSYGQQSSYGQQPPTSYPPQTGSYSQ--APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQE 287
G + G P + GS + AP Q + G++ R P G G +
Sbjct: 269 GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLP-GERG--RPGAPGPAGARGND 325
Query: 288 SG-GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-GERGGFNKPGGPM 345
G +GP +GP GF G + G G +G G+ G +G +PG P
Sbjct: 326 GATGAAGPPGPTGPAGPP-------GFP-GAVGAKGEAGPQGPRGSEGPQGVRGEPGPP- 376
Query: 346 DEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI 405
GP GP +P D A +G N + + F G G P
Sbjct: 377 --GPAGAAGPAGNPGADGQPGA---KGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKG 431
Query: 406 YLDKETGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL 463
E G P KGD E P G++ + AR +P + G
Sbjct: 432 N-SGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRG------ARGEPGPTGLPG-- 482
Query: 464 PPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQ 521
PP RGGPG G PG G G +G G+RG P GP+GS G G
Sbjct: 483 --------PPGERGGPGSRGFPGAD-GVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAG 533
Query: 522 HRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRG 581
+PG +P P+G PP P G GR GP G G RG
Sbjct: 534 LPGAKGLTGSPG----------------SPGPDGKTGPP--GPAGQDGRPGPPGPPGARG 575
Query: 582 --GLMDRGGP-GGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ 633
G+M GP G G+ G+RG G G G D G GP GP GP E+
Sbjct: 576 QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD----GEAGAQGPPGPAGPAGER 631
Query: 634 MGGRRGGRGGPG 645
G +G G PG
Sbjct: 632 --GEQGPAGSPG 641
Score = 85.1 bits (209), Expect = 2e-16
Identities = 146/577 (25%), Positives = 187/577 (32%), Gaps = 101/577 (17%)
Query: 145 PQDGNKPTETSQPQSS--TGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPT--- 199
P + +P E P + TG P G + P P +P PP P
Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSP----GPDGKTGPPGPAGQDGRP--GPPGPPGARGQ 576
Query: 200 ----SYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ 255
+ + + + ++ G P + G G+ + G P + G
Sbjct: 577 AGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGP 636
Query: 256 APSQYSQ----------QSSSYGQQSSFRQDHPSSMGVYGQES--GGFSGPGENRSMSGP 303
A S Q ++ G+Q P +G G G PGE R + GP
Sbjct: 637 AGSPGFQGLPGPAGPPGEAGKPGEQGV-----PGDLGAPGPSGARGERGFPGE-RGVQGP 690
Query: 304 DN----RGRGRGGFDRGGMSRGGRGGGRGGMGA-------GERGGFNKPGGPMDEGPDLD 352
RG + G G G G GA GERG PG D G
Sbjct: 691 PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGP 750
Query: 353 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETG 412
G P +D V+GL + A G + G P + G
Sbjct: 751 KGADGSPGKDG------VRGLTGPIGPPGPAGAPGDKGESGPSGPAG-PTGARGAPGDRG 803
Query: 413 KPKGDATVSYEDPPTA------KAAVEWFDGKDFQGSKLKVSLARKKPPMNSM------- 459
+P + PP A K K G A P+ ++
Sbjct: 804 EPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKG 863
Query: 460 -RGGLPPREGRGMP-------PPLRGGPGGPGGPGGPMGRMGGRG-----------GDRG 500
RG P G P PP G GP GP GP G+ GG+G G+ G
Sbjct: 864 ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG 923
Query: 501 GFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE-GFLPP 559
P GP G +G+P G AG P P Q A + + E GF P
Sbjct: 924 PPGPPGPAGEKGSPGADGP----AGAPGTPGP----QGIAGQRGVVGLPGQRGERGF--P 973
Query: 560 PFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGG 617
P P G+ G+ GP G G RG G PG G G G G G G D
Sbjct: 974 GLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAK 1033
Query: 618 GRRG--GPGGPPGPLMEQMGGRRGGRGGPGKM-DKGE 651
G RG GP GPPG G G G GK D+GE
Sbjct: 1034 GDRGETGPAGPPG--APGAPGAPGPVGPAGKSGDRGE 1068
Score = 84.7 bits (208), Expect = 2e-16
Identities = 129/460 (28%), Positives = 151/460 (32%), Gaps = 59/460 (12%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY-SQAPSQYSQQSSSYGQQSSFRQDHPS 279
G P G + S G+ G+ TGS S P + GQ R P
Sbjct: 512 GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDG--RPGPPG 569
Query: 280 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG-------A 332
G GQ +G PG + P G G + G+ G G G A
Sbjct: 570 PPGARGQ-AGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPA 628
Query: 333 GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVV 392
GERG G P +G GPP + + + G F + GV
Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688
Query: 393 KMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARK 452
G G P D P A + + G + L
Sbjct: 689 GPPGPAGP-------RGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP 741
Query: 453 KPPMNSM----RGGLPPREG-RGM-----PPPLRGGPG--GPGGPGGPMGRMGGRG--GD 498
K G P ++G RG+ PP G PG G GP GP G G RG GD
Sbjct: 742 KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD 801
Query: 499 RGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLP 558
RG P GP G G P G + PG P P G
Sbjct: 802 RGEPGPPGPAGFAGPPGADGQPGAKG------EPGDAGAK-------GDAGPPGPAGPAG 848
Query: 559 PPFP-----PPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRG 609
PP P PG G RG GP G G G G PG G G G G GG+G
Sbjct: 849 PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG 908
Query: 610 MDRGGFG-GGRRG--GPGGPPGPLMEQ-MGGRRGGRGGPG 645
RG G GR G GP GPPGP E+ G G G PG
Sbjct: 909 -PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPG 947
Score = 79.0 bits (193), Expect = 1e-14
Identities = 77/231 (33%), Positives = 83/231 (35%), Gaps = 54/231 (23%)
Query: 453 KPPMNSMRGGLPPREGRGMP-----PPLRG--------GPGGPGGPGGPMGRMG--GRGG 497
KP RG P+ RG+P P ++G G G GP GP G G G G
Sbjct: 237 KPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG 296
Query: 498 DRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFL 557
G PRG G RG P G R D G P P G
Sbjct: 297 APGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAG----------------PPGPTGPA 340
Query: 558 PPP-FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--------GFRGGR 608
PP FP G +G GP G RG G RG PG G G G G +G
Sbjct: 341 GPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGAN 400
Query: 609 G----MDRGGFGGGR----RGGPGGPPGPLMEQMGGRRGGRGGPG-KMDKG 650
G GF G R GPGGPPGP G G G PG K D G
Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPGP-----KGNSGEPGAPGSKGDTG 446
Score = 77.4 bits (189), Expect = 4e-14
Identities = 148/526 (28%), Positives = 180/526 (34%), Gaps = 68/526 (12%)
Query: 142 PTRPQDGNKPTETSQ-----PQSSTG--GYNQPSLGYGQSNY-SYPQVPGSYPMQPVTAP 193
P P PT+ P+ TG G P+ G+ P +PG P P P
Sbjct: 93 PVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGP-PGPP--GP 149
Query: 194 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 253
P P + SY Y +++T G S G G + G PP + PQ +
Sbjct: 150 PGPPGLGGNFAPQLSY---GYDEKST-GGISVPGPMGPSGPRGLPG--PPGAPGPQ--GF 201
Query: 254 SQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGF 313
P + + +S P G G E+G PGE R GP G
Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDG-EAGKPGRPGE-RGPPGPQGARGLPGTA 259
Query: 314 DRGGMSRGGRG--GGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYV 370
GM +G RG G G G AG G +PG P + G +GP P E A
Sbjct: 260 GLPGM-KGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGP 318
Query: 371 QGL--NDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPP 426
G ND T G TG G P G E P
Sbjct: 319 AGARGNDGAT-----------GAAGPPGPTG----------PAGPPGFPGAVGAKGEAGP 357
Query: 427 TAKAAVEWFDG-KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG-- 483
E G + G A P N G P +G P + G PG PG
Sbjct: 358 QGPRGSEGPQGVRGEPGPPGPAGAA--GPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415
Query: 484 GPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRT 543
GP GP G GG G +G G GS+G+ +G G P P R
Sbjct: 416 GPSGPQG-PGGPPGPKGNSGEPGAPGSKGD-TGAKGEPGPVGVQGPPGPAGEEGKRGARG 473
Query: 544 ECNQCKAPKPEGFLPPP----FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 599
E P P G P FP G G GP G RG G +G PG GR G
Sbjct: 474 EPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG---EAGRPG 530
Query: 600 DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 645
+ G G +G+ G G G GPPGP + GR G G PG
Sbjct: 531 E-AGLPGAKGL-TGSPGSPGPDGKTGPPGPAGQD--GRPGPPGPPG 572
Score = 75.5 bits (184), Expect = 1e-13
Identities = 114/456 (25%), Positives = 151/456 (33%), Gaps = 81/456 (17%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----APSQYSQQSSSYGQQSSFRQD 276
G P G G+ G PT G + P+ ++ + GQ + +
Sbjct: 770 GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA--KG 827
Query: 277 HPSSMGVYGQE-----SGGFSGPGENRSMSGPDNRGR-------GRGGFDRGGMSRGGRG 324
P G G +G PG ++ P +G G GF G R G
Sbjct: 828 EPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFP-GAAGRVGPP 886
Query: 325 GGRGGMG-------AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 377
G G G AG+ GG G G ++GPP P + + G +
Sbjct: 887 GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946
Query: 378 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVEWF 435
Q GVV + + G+ L +G+P +G + S E P
Sbjct: 947 GTPGPQGIAGQRGVVGLPGQRGERGFP-GLPGPSGEPGKQGPSGASGERGPPGPMGPPGL 1005
Query: 436 DGKDFQGSKLKVSLARKKPPMNSMRGGLPPR--EGRGMPPPLRGGPGGPG---------- 483
G + + A P + G R G PP G PG PG
Sbjct: 1006 AGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGD 1065
Query: 484 -------GPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 536
GP GP+G +G RG P GP+G RG+ G R G+
Sbjct: 1066 RGETGPAGPAGPVGPVGARG-------PAGPQGPRGDKGETGEQGDRGIK--------GH 1110
Query: 537 QNFAWRTECNQCKAPKPEGFLPPPFPPPG-GDRGRGGPGGMRGGRGGLMDRGGPGGMFRG 595
+ F+ G PP PP G++G G G G RG G PG
Sbjct: 1111 RGFS--------------GLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLN 1156
Query: 596 GRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGP 629
G G G G RG G D G G GP GPPGP
Sbjct: 1157 GLPGPIGPPGPRGRTG-DAGPVGPPGPPGPPGPPGP 1191
Score = 74.3 bits (181), Expect = 3e-13
Identities = 160/582 (27%), Positives = 197/582 (33%), Gaps = 103/582 (17%)
Query: 128 PAYPA--YGQQPAATAPT---RPQDGNKPTETSQP--QSSTGGYNQPSLGYGQSNYSYPQ 180
PA PA G+Q A +P P P E +P Q G P + +P
Sbjct: 624 PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPG 683
Query: 181 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 240
G V PP ++ P + + G P + G Q + G Q G+
Sbjct: 684 ERG------VQGPPGPAGPRGANGAP-----GNDGAKGDAGAPGAPGSQGAPGLQGMPGE 732
Query: 241 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD--HPSSMGVYGQESGGFSGPGENR 298
+ P G A + + S P G G + G SGP
Sbjct: 733 RGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK--GESGP---- 786
Query: 299 SMSGPDNRGRGRGG-FDRGGMSRGGRGGGRGGMGA-GERGGFNKPG---GPMDEGPDLDL 353
SGP RG DRG G G G GA G+ G +PG D GP
Sbjct: 787 --SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844
Query: 354 GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM---NKRTGQPMIHIYLDKE 410
GP P + A +G S F G V + G P KE
Sbjct: 845 GPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKE 904
Query: 411 TGK-PKGDA-------TVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG- 461
GK P+G+ V PP A + G D A P + G
Sbjct: 905 GGKGPRGETGPAGRPGEVGPPGPP-GPAGEKGSPGADGPAG------APGTPGPQGIAGQ 957
Query: 462 ----GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPS 515
GLP + G RG PG PG P G G+ G G G+RG P GP G G P
Sbjct: 958 RGVVGLPGQRGE------RGFPGLPG-PSGEPGKQGPSGASGERGPPGPMGPPGLAGPPG 1010
Query: 516 GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECNQCKAPKPEGF--LPPPFPPPG--GD 567
G + G P +PG R E P G P P P G GD
Sbjct: 1011 ESGR-EGAPGAEGSPGRDGSPGAKGD----RGETGPAGPPGAPGAPGAPGPVGPAGKSGD 1065
Query: 568 RGRGGPGGMRGGRGGLMDRG--GPGGMFRGGRG-----GDRG--GFRGGRGM-------- 610
RG GP G G G + RG GP G RG +G GDRG G RG G+
Sbjct: 1066 RGETGPAGPAGPVGPVGARGPAGPQGP-RGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124
Query: 611 ---DRGGFGG----GRRGGPGGPPGPLMEQMGGRRGGRGGPG 645
++G G G RG PG P + + G G G PG
Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPG 1166
Score = 70.5 bits (171), Expect = 5e-12
Identities = 72/197 (36%), Positives = 81/197 (41%), Gaps = 34/197 (17%)
Query: 478 GPGGPGGPGGPMGRMG--GRGGDRG--GFP-PRGPRGSRGNPSGGGNV---------QHR 523
GP G GP GP G G GR G G G P P GP G G P GGN +
Sbjct: 112 GPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKS 171
Query: 524 AGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGL 583
G P P + R AP P+GF PP P G+ G GP G RG G
Sbjct: 172 TGGISVPGPMGPS---GPRGLPGPPGAPGPQGFQGPPGEP--GEPGASGPMGPRGPPGPP 226
Query: 584 MDRGGPGGMFRGGRGGDRG--GFRGGRGM-DRGGFGG--GRRG--------GPGGPPGPL 630
G G + GR G+RG G +G RG+ G G G RG G GP GP
Sbjct: 227 GKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPK 286
Query: 631 MEQMGGRRGGRGGPGKM 647
E G G G PG+M
Sbjct: 287 GEP--GSPGENGAPGQM 301
Score = 42.0 bits (97), Expect = 0.002
Identities = 78/328 (23%), Positives = 96/328 (29%), Gaps = 56/328 (17%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G P G G + G+ P P + G P ++ S + P
Sbjct: 893 GPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP-PGPAGEKGSPGADGPAGAPGTPGP 951
Query: 281 MGVYGQ-----------ESG--GFSGPGENRSMSGPDNRGRGRGGFD-------RGGMSR 320
G+ GQ E G G GP GP RG G
Sbjct: 952 QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGE 1011
Query: 321 GGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 380
GR G G G+ R G PG D G GPP P + G +
Sbjct: 1012 SGREGAPGAEGSPGRDG--SPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGET 1069
Query: 381 DLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDF 440
A G V G P+GD + E F G
Sbjct: 1070 GPAGPAGPVGPVGARGPAGPQ-----------GPRGDKGETGEQGDRGIKGHRGFSGLQG 1118
Query: 441 ----------QGSKLKVSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPGGPM 489
QG A + P S G P ++G G+P P+ GP GP G G
Sbjct: 1119 PPGPPGSPGEQGPSGASGPAGPRGPPGS--AGAPGKDGLNGLPGPI--GPPGPRGRTGDA 1174
Query: 490 GRMGGRGGDRGGFPPRGPRGSRGNPSGG 517
G +G G P GP G G PS G
Sbjct: 1175 GPVGPPG-------PPGPPGPPGPPSAG 1195
Score = 29.6 bits (65), Expect = 9.3
Identities = 35/113 (30%), Positives = 40/113 (35%), Gaps = 19/113 (16%)
Query: 547 QCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRG--------GRGGLMDR----GGPGGMFR 594
+C P+G P G G G G RG GR G+ + G PG
Sbjct: 90 ECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGP 149
Query: 595 GGRGGDRGGF--RGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 645
G G G F + G D GG GP GP GP G G G PG
Sbjct: 150 PGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGP-----RGLPGPPGAPG 197
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 90.9 bits (224), Expect = 3e-18
Identities = 143/493 (29%), Positives = 171/493 (34%), Gaps = 119/493 (24%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G P + G + G Q G+ P P + G R P S
Sbjct: 567 GLPGARGLTGNPGVQGPEGKLGPLGAPGEDG----------------------RPGPPGS 604
Query: 281 MGVYGQESGGFSGPGENRSMSGPDNRGR-GRGGF--DRGGMSRGGRGGGRGGMG----AG 333
+G+ GQ G PG S P G G G RG + G G G +G AG
Sbjct: 605 IGIRGQP-GSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAG 663
Query: 334 ERGGFNKPGG------PMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK 387
ERG PG P GP + G P D D A+ G
Sbjct: 664 ERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG--- 720
Query: 388 QCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV 447
+ G+ + G H D G P T PP QG +
Sbjct: 721 EPGITGLPGEKGMAGGH-GPDGPKGSPGPSGTPGDTGPP------------GLQGMPGER 767
Query: 448 SLARKKPPMNSMRGGLPPR--EG-------RGMPPPLRGGPGGPGGPGGPMGRMGGRGGD 498
+A P RGG+ + EG RG+P PL GP GP GP G G G RG
Sbjct: 768 GIAGTPGPKGD-RGGIGEKGAEGTAGNDGARGLPGPL--GPPGPAGPTGEKGEPGPRG-- 822
Query: 499 RGGFPPRGPRGSRGNP-SGGGNVQHRAGDWQCPNPGCGNQNFAWRT----ECNQCKAPKP 553
GP GSRGNP S G N A + P G + +P P
Sbjct: 823 -----LVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGP 877
Query: 554 EGFLPPPFP-----------------PPG-----GDRGRGGPGGMRGGRG-----GLMDR 586
+G P P PPG G GR GP G G G G +
Sbjct: 878 QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGK 937
Query: 587 GGPGGMFRG-----GRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPL-------ME 632
GP G+ RG GR GDRG G GG G D+G G + GP GPPGP +
Sbjct: 938 EGPPGL-RGDPGSHGRVGDRGPAGPPGGPG-DKGDPGEDGQPGPDGPPGPAGTTGQRGIV 995
Query: 633 QMGGRRGGRGGPG 645
M G+RG RG PG
Sbjct: 996 GMPGQRGERGMPG 1008
Score = 88.2 bits (217), Expect = 2e-17
Identities = 147/542 (27%), Positives = 182/542 (33%), Gaps = 117/542 (21%)
Query: 122 SAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQV 181
S + P A P PQ + ET P G P L P
Sbjct: 377 SGFPGNPGMKGEAGPTGARGPEGPQ--GQRGETGPP----GPVGSPGLPGAIGTDGTPGA 430
Query: 182 PGSYPMQPVTAPP-SYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 240
G + PP S P Q ++ Q Q G P G+ G+ +G
Sbjct: 431 KGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGI 490
Query: 241 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 300
Q P P + G + P ++G G G G NR
Sbjct: 491 QGPIGPPGEEGKRGP-------------------RGDPGTVGPPGPV--GERGAPGNRGF 529
Query: 301 SGPDNRGRGRGGF-DRGGMSRGGRGGGRGGMGA----GERGGFNKPGGPMDEGPDLDLGP 355
G D +G +RG + G G +G G G G G P +GP+ LGP
Sbjct: 530 PGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGP 589
Query: 356 PVDPDEDS---DNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETG 412
P ED +I ++G S+ G+ +G P G
Sbjct: 590 LGAPGEDGRPGPPGSIGIRGQPGSM------------GLPGPKGSSGDP----------G 627
Query: 413 KP--KGDATVSYEDPPTAKAAVEWFDGKDFQ-GSKLKVSLARKKPPMNSMRGGLPPREGR 469
KP G+A V P + A GKD + G V PP GL G
Sbjct: 628 KPGEAGNAGV-----PGQRGA----PGKDGEVGPSGPVG-----PP------GLAGERGE 667
Query: 470 GMPPPLRGGPG--GPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAG 525
PP G G GP GP G G+ G +G GD G P GPRG RGNP G
Sbjct: 668 QGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG------- 720
Query: 526 DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMD 585
PG E P+G P P P G G GP G++G G
Sbjct: 721 -----EPGI----TGLPGEKGMAGGHGPDG--PKGSPGPSGTPGDTGPPGLQGMPGERGI 769
Query: 586 RGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGRRGGRGG 643
G PG GDRGG G +G + G RG GP GPPGP G G +G
Sbjct: 770 AGTPGPK------GDRGGI-GEKGAEGTAGNDGARGLPGPLGPPGP-----AGPTGEKGE 817
Query: 644 PG 645
PG
Sbjct: 818 PG 819
Score = 85.1 bits (209), Expect = 2e-16
Identities = 133/458 (29%), Positives = 161/458 (35%), Gaps = 78/458 (17%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G P S G+ G + G P P + G P Q ++G P
Sbjct: 315 GAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLG--PQGAPGQRGAHGMPGK-----PGP 367
Query: 281 MGVYG-QESGGFSGPGENRSMSGPDN-RGRGRGGFDRGGMSRGGRGGGRGGMGA----GE 334
MG G S GF G + +GP RG RG G G G GA G
Sbjct: 368 MGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGT 427
Query: 335 RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 394
G G P GP GPP P QG+ + F + G
Sbjct: 428 PGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGP---QGIRGQPGDPGVPGFKGEAGP--- 481
Query: 395 NKRTGQPMIH-----IYLDKETGK--PKGD-ATVSYEDPPTAKAAV--EWFDGKDF---- 440
G+P H I E GK P+GD TV P + A F G D
Sbjct: 482 ---KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGP 538
Query: 441 QGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG--GPGGPMGRMGGRGGD 498
+G++ + P S G P R G P RG G PG GP G +G +G G D
Sbjct: 539 KGAQGERGPVGSSGPKGSQ--GDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGED 596
Query: 499 RGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFL 557
PP G G RG P G + PG GN Q AP +G +
Sbjct: 597 GRPGPP-GSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVP-----GQRGAPGKDGEV 650
Query: 558 PP--PFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRG 613
P P PPG G+RG GP G G +G G PG GG+ GD+G
Sbjct: 651 GPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPG---EGGKPGDQGV---------- 697
Query: 614 GFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGE 651
G G GPL G RG RG PG ++GE
Sbjct: 698 -------PGDPGAVGPL-----GPRGERGNPG--ERGE 721
Score = 80.5 bits (197), Expect = 5e-15
Identities = 116/439 (26%), Positives = 149/439 (33%), Gaps = 56/439 (12%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G P S G + G + G + P + G Q + S+ + +
Sbjct: 135 GPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQ 194
Query: 281 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNK 340
M ++SG S G GP RG G+ GG AG G +
Sbjct: 195 MAGLDEKSGLGSQVGLMPGSVGPVG--------PRGPQGLQGQQGG-----AGPTGPPGE 241
Query: 341 PGGPMDEGPDLDL---GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 397
PG P GP GPP P ED + G F G+ +
Sbjct: 242 PGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGH 301
Query: 398 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 457
G H L+ G+ + P A+ + G + + L + P
Sbjct: 302 RG----HKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR--LGPQGAPGQ 355
Query: 458 SMRGGLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMGGRG--GDRGGFPPRGPRGS 510
G+P + G P + G G PG PG GP G G G G RG P GP GS
Sbjct: 356 RGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGS 415
Query: 511 RGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGR 570
G P G +PG P G PP P G +G
Sbjct: 416 PGLPGAIGTDGTPGAKGPTGSPGTSG----------------PPGSAGPPGSP--GPQGS 457
Query: 571 GGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG--GP 626
GP G+RG G D G PG G G+ G G +G G G RG PG GP
Sbjct: 458 TGPQGIRGQPG---DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGP 514
Query: 627 PGPLMEQMGGRRGGRGGPG 645
PGP+ E+ G G RG PG
Sbjct: 515 PGPVGER--GAPGNRGFPG 531
Score = 79.7 bits (195), Expect = 8e-15
Identities = 125/447 (27%), Positives = 148/447 (33%), Gaps = 104/447 (23%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G P S G+ G G Q P P G + P Q S Q +
Sbjct: 831 GNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGE-PGQKGDAGSPGPQGLAGSPGPHGP 889
Query: 281 MGVYGQESG-------GFSG-PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA 332
GV G + G G +G PG + P G G + G G RG G+
Sbjct: 890 NGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGS 949
Query: 333 ----GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQ 388
G+RG PGGP D+G D G P D G Q
Sbjct: 950 HGRVGDRGPAGPPGGPGDKG---DPGEDGQPGPDGPPGPAGTTG---------------Q 991
Query: 389 CGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 446
G+V M + G E G P G A + PT
Sbjct: 992 RGIVGMPGQRG----------ERGMPGLPGPAGTPGKVGPTG------------------ 1023
Query: 447 VSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPP 504
+ K PP G + P G P GP GP G G GR G G GDRG P
Sbjct: 1024 -ATGDKGPP-----GPVGPPGSNG--PVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGP 1075
Query: 505 RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPP 564
G GS+G P G V Q +PG P PP
Sbjct: 1076 AGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRG-----------------------PIGPP 1112
Query: 565 G--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRR 620
G G RG GP G RG +G DRG G G G +G G G G ++G G
Sbjct: 1113 GRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNG-EQGSAGIPGP 1171
Query: 621 GGPGGPPGPLMEQMGGRRGGRGGPGKM 647
GP GPPGP+ G G G PG +
Sbjct: 1172 FGPRGPPGPV-----GPSGKEGNPGPL 1193
Score = 77.0 bits (188), Expect = 5e-14
Identities = 146/533 (27%), Positives = 172/533 (32%), Gaps = 119/533 (22%)
Query: 182 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQ 241
PG Q + PP P + Q G P + G G++ + G++
Sbjct: 671 PGPTGFQGLPGPPGPPG-----------EGGKPGDQGVPGDPGAVGPLGPRGERGNPGER 719
Query: 242 PPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG-GFSG-PGENRS 299
G A G + P G G G G PGE
Sbjct: 720 GEPGITGLPGEKGMAG----------GHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGI 769
Query: 300 MSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-GERGGFNKPG--GPMDE----GPDLD 352
P +G DRGG+ G G G GA G G PG GP E GP
Sbjct: 770 AGTPGPKG------DRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGL 823
Query: 353 LGPPV---DPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK 409
+GPP +P +N G D Q GV GQ
Sbjct: 824 VGPPGSRGNPGSRGENGPTGAVGFAGPQGPDG------QPGVKGEPGEPGQK-------G 870
Query: 410 ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGR 469
+ G P P G+ QG PP + G P GR
Sbjct: 871 DAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQG-----------PPGAT---GFPGSAGR 916
Query: 470 GMPPPLRGGPGGPGGPGGPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGGNVQHRA 524
PP GP G GP GP+G G G GD G G RG G P G G+
Sbjct: 917 VGPP----GPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPG 972
Query: 525 GDWQC-----PNPG--CGNQNFAW----RTECNQCKAPKPEGFLPPPFP--------PPG 565
D Q P P G + R E P P G P PPG
Sbjct: 973 EDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPG 1032
Query: 566 --GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGM--DRGGFG 616
G G GP G G G + G PG G GDRG G G +G G G
Sbjct: 1033 PVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVG 1092
Query: 617 ----GGRRGGPG--GPPGPLMEQMGGRRGGRGGPG----KMDKGEHRQERRDR 659
G+RG PG GP GP GR G RG PG + DKG+H +R DR
Sbjct: 1093 APGDAGQRGDPGSRGPIGP-----PGRAGKRGLPGPQGPRGDKGDH-GDRGDR 1139
Score = 76.6 bits (187), Expect = 7e-14
Identities = 155/607 (25%), Positives = 202/607 (33%), Gaps = 130/607 (21%)
Query: 151 PTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYP--PTSYSSTQPTS 208
P + P+ G +P Q P VPG P P PP +P P ++P S
Sbjct: 136 PPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQ-PGAP--GPPGHPSHPGPDGLSRPFS 192
Query: 209 YDQSSYSQQNTYGQ-----PSSYGQQSSYGQQSSYGQQP---PTSYPPQTGSY------- 253
+ +++ G P S G G Q GQQ PT P + G
Sbjct: 193 AQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIG 252
Query: 254 SQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG-GFSGP----------------GE 296
S+ P + G+ R +P +G G GF G G
Sbjct: 253 SRGPEGPPGKPGEDGEPG--RNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGP 310
Query: 297 NRSMSGPDNRGRGRGGFDRGGMSR-GGRG--GGRGGMGA----GERGGFNKPGGPMDEGP 349
+ P ++G G M G RG G RG +G G+RG PG P GP
Sbjct: 311 KGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGP 370
Query: 350 ---------------DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 394
+ GP + G V L G
Sbjct: 371 LGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGA 430
Query: 395 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD-------FQGSKLKV 447
TG P T P G A P + G+ F+G
Sbjct: 431 KGPTGSP--------GTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGE---- 478
Query: 448 SLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPG--GPGGPGGPMGRMGGRG------- 496
+ + +P + ++G G P EG+ P RG PG GP GP G G G RG
Sbjct: 479 AGPKGEPGPHGIQGPIGPPGEEGKRGP---RGDPGTVGPPGPVGERGAPGNRGFPGSDGL 535
Query: 497 -------GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCK 549
G+RG GP+GS+G+P G NPG +
Sbjct: 536 PGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPE----GKLGPLG 591
Query: 550 APKPEGFLPPPFPPPG-GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----G 603
AP +G P PP G RG+ G G+ G +G D G PG G G RG G
Sbjct: 592 APGEDG---RPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDG 648
Query: 604 FRGGRG-MDRGGFGG--GRRGGPG--------GPPGPLMEQMGGRRGGR---GGPGKMDK 649
G G + G G G +G PG GPPGP E GG+ G + G PG +
Sbjct: 649 EVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGE--GGKPGDQGVPGDPGAVGP 706
Query: 650 GEHRQER 656
R ER
Sbjct: 707 LGPRGER 713
Score = 59.7 bits (143), Expect = 8e-09
Identities = 70/218 (32%), Positives = 84/218 (38%), Gaps = 24/218 (11%)
Query: 457 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNP 514
N RG + G+ P + G G PG P GP G G RG G +G PRGP+G G P
Sbjct: 106 NFGRGRKGQKGEPGLVPVVTGIRGRPG-PAGPPGSQGPRGERGPKGRPGPRGPQGIDGEP 164
Query: 515 S--GGGNVQHRAGDWQCPNP-GCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 571
G G P P G A ++ + L P P G RG
Sbjct: 165 GVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQ 224
Query: 572 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMD----------RGGFGG-- 617
G G +GG G G PG G G RG G G G D GF G
Sbjct: 225 GLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSP 284
Query: 618 GRRGGPGGPPGPLMEQMGGRRGGRGGPGKM----DKGE 651
G RG PG P P ++ G +G G G++ KGE
Sbjct: 285 GARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGE 322
Score = 59.3 bits (142), Expect = 1e-08
Identities = 69/237 (29%), Positives = 86/237 (36%), Gaps = 54/237 (22%)
Query: 460 RGGLPPREGRGMP--PPLRGGPGGPGGPGGP------------------MGRMGGRGGDR 499
+G PR +G+ P + G PG PG PG P + G G
Sbjct: 149 KGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQV 208
Query: 500 GGFP-------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK 552
G P PRGP+G +G GG G+ P P +
Sbjct: 209 GLMPGSVGPVGPRGPQGLQGQ-QGGAGPTGPPGEPGDPGP------------MGPIGSRG 255
Query: 553 PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM 610
PEG PP P G+ GR G G G G RG PG G G RG G G +G
Sbjct: 256 PEG--PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKG- 312
Query: 611 DRGGFGGGRRGGPGGPPGPL-------MEQMGGRRGGRGGPGKMDKGEHRQERRDRP 660
+ G G GP GP G + M GR G +G PG+ +G H + P
Sbjct: 313 EVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQ--RGAHGMPGKPGP 367
Score = 53.9 bits (128), Expect = 5e-07
Identities = 129/518 (24%), Positives = 155/518 (29%), Gaps = 123/518 (23%)
Query: 137 PAATAPTRPQDGNKPTETSQPQSSTG-----GYNQPSLGYGQSNYSYPQVPGSYPMQPVT 191
P PT + P P S G G N P+ G ++ PQ P P V
Sbjct: 806 PGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPT---GAVGFAGPQGPDGQP--GVK 860
Query: 192 APPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPP---TSYPP 248
P P + P Q G P +G G + G Q P T +P
Sbjct: 861 GEPGEPGQKGDAGSP--------GPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPG 912
Query: 249 QTGSYSQ-----APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQE--SGGFSGPGENRS-- 299
G AP + + P S G G +G GPG+
Sbjct: 913 SAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPG 972
Query: 300 ---MSGPDNRGRGRGGF-DRGGMSRGGRGGGRGGMG----AGERGGFNKPGGPMDEGPDL 351
GPD G RG + G+ G RG G AG G G D+GP
Sbjct: 973 EDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPG 1032
Query: 352 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET 411
+GPP N + G D + G V G P
Sbjct: 1033 PVGPP------GSNGPVGEPGPEGPAGNDGTPG---RDGAVGERGDRGDP-------GPA 1076
Query: 412 GKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGM 471
G P P A + GS+ + PP + + GLP
Sbjct: 1077 GLPGSQGAPGTPGPVGAPGDA---GQRGDPGSRGPIG-----PPGRAGKRGLP------- 1121
Query: 472 PPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPN 531
GP GP G G G R GDRG RG G +G P G PN
Sbjct: 1122 ---------GPQGPRGDKGDHGDR-GDRGQKGHRGFTGLQGLPGPPG-----------PN 1160
Query: 532 PGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGG 591
G Q A +P PF P G G GP G G G L G PG
Sbjct: 1161 ---GEQGSAG---------------IPGPF-GPRGPPGPVGPSGKEGNPGPLGPIGPPG- 1200
Query: 592 MFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGP 629
RG G + G G GP GPPGP
Sbjct: 1201 -VRGSVG------------EAGPEGPPGEPGPPGPPGP 1225
Score = 37.7 bits (86), Expect = 0.034
Identities = 38/112 (33%), Positives = 42/112 (37%), Gaps = 11/112 (9%)
Query: 529 CP----NPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLM 584
CP PG GN NF K K E L P G G GP G +G RG
Sbjct: 93 CPVCSQTPGGGNTNFG-----RGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERG 147
Query: 585 DRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGG 636
+G PG RG +G D G+ G G GP G P QM G
Sbjct: 148 PKGRPGP--RGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAG 197
Score = 36.6 bits (83), Expect = 0.076
Identities = 55/235 (23%), Positives = 68/235 (28%), Gaps = 29/235 (12%)
Query: 128 PAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPM 187
P P P PT P P S G +P N P G+
Sbjct: 1007 PGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGE 1066
Query: 188 QPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYP 247
+ P P S Q G P G GQ+ G + P P
Sbjct: 1067 RGDRGDPG----------PAGLPGS----QGAPGTPGPVGAPGDAGQRGDPGSRGPIGPP 1112
Query: 248 PQTGSYS-QAPSQYSQQSSSYGQQSSFRQ-DHPSSMGVYG----------QESGGFSGPG 295
+ G P +G + Q H G+ G Q S G GP
Sbjct: 1113 GRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPF 1172
Query: 296 ENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGP 349
R GP G + G + G G RG +G AG G +PG P GP
Sbjct: 1173 GPRGPPGPVGPSGKEG--NPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGP 1225
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 90.9 bits (224), Expect = 3e-18
Identities = 180/669 (26%), Positives = 234/669 (34%), Gaps = 117/669 (17%)
Query: 53 TQAQTTATYGQTAYA-TSYGQPPTVEGTST------GYTTPTAPQAYSQPVQGYGTGAYD 105
T+A+ T+ + A A TS +PP S+ G T T P A P GT
Sbjct: 460 TEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTS-GTSTPR 518
Query: 106 TTTATVTTTQASYAAQSAYGTQPAYPAYGQQ-PAATAPTRPQDGNKPTETS--------- 155
T A T A ++ G++ + A + P P RP + S
Sbjct: 519 TAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPR 578
Query: 156 QPQSSTGGYNQPSLGYGQ----------SNYSYPQVPGSYPMQPVTAPPSYP-------P 198
QPQ S L Q S YS + GS P + PP P
Sbjct: 579 QPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGP 638
Query: 199 TSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTG------- 251
+ YG P G + GQ+ G P ++ G
Sbjct: 639 PGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGL 698
Query: 252 SYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQE-SGGFSGPGENRSMSGP--DNRGR 308
S + P G HP G G E S G G + + GP D +
Sbjct: 699 SGNPGPPGRKGHKGYPGPAG-----HPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPK 753
Query: 309 G-RGGFDRGGM-----SRGGRG-----GGRGGMGA-GERGGFNKPGGPMDEGPDLDLGPP 356
G RG G+ S G RG G RG MG G G F + G P +G +LG P
Sbjct: 754 GSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLP 813
Query: 357 VDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK-ETGKPK 415
P V GL + + + G+ + G+P + DK E G P
Sbjct: 814 GPPG---------VPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKG--DKGEQGVPG 862
Query: 416 GDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV----SLARKKPP-MNSMRGGLPPREGRG 470
++ ++ + + G KV S+ PP G + P G
Sbjct: 863 VSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNG 922
Query: 471 MPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGG--------NVQH 522
P ++G PG G PG P G++G G D G P G G G P G V+
Sbjct: 923 -PEGMKGKPGARGLPG-PRGQLGPEG-DEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKG 979
Query: 523 RAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFL----PPPFPPPGGDRGRGGPGGMRG 578
GD P P G Q F GF+ P GDRG GP G+ G
Sbjct: 980 EPGDPGRPGP-VGEQGFM--------------GFIGLVGEPGIVGEKGDRGMMGPPGVPG 1024
Query: 579 GRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGG 636
+G + G PGGM G G +G G RG GM RG G R GP GP GP EQ G
Sbjct: 1025 PKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGM-RGAKG---RRGPRGPDGPAGEQ--G 1078
Query: 637 RRGGRGGPG 645
RG +G PG
Sbjct: 1079 SRGLKGPPG 1087
Score = 80.5 bits (197), Expect = 5e-15
Identities = 144/546 (26%), Positives = 182/546 (33%), Gaps = 137/546 (25%)
Query: 137 PAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSY 196
P P PQ P P+ G +P L G++ P P +
Sbjct: 1128 PGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLP-GEAGMKGDLGPLGTPGEQGLIGQRG 1186
Query: 197 PPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA 256
P + P D + G P G+ GQ+ G+ P P TG +
Sbjct: 1187 EPGLEGDSGPMGPD----GLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGV--RG 1240
Query: 257 PSQYSQQSSSYGQQSSFR----QDHPSSMGVYGQESG-GFSGPGENRSMSGPDNR-GR-- 308
P S + G+ + Q MGV G G GP +R GP GR
Sbjct: 1241 PEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMG 1300
Query: 309 -----GRGGFD--RGGMSRGGRGGGRGGMGA-GERG-GFNKPGGPMDEGPDLDLGPPVDP 359
G G+D +G + G G +G G GE G PG P D GP D G +P
Sbjct: 1301 AQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEP 1360
Query: 360 DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 419
+ VQGL G+P + G+P
Sbjct: 1361 GDPGYPGQEGVQGLR------------------------GKP-------GQQGQPGHPGP 1389
Query: 420 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREG----RGMPPPL 475
+ P +K A +G K K A G P R G +G+P P
Sbjct: 1390 RGWPGPKGSKGA---------EGPKGKQGKA-----------GAPGRRGVQGLQGLPGPR 1429
Query: 476 ----RGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGD 526
R G G GP G GR G G GD G P GP G RGNP G
Sbjct: 1430 GVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAG-------- 1481
Query: 527 WQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRG--GRGGLM 584
P +G PP F G G+ GP G RG GR GL
Sbjct: 1482 -----------------------LPGAQG--PPGFKGESGLPGQLGPPGKRGTEGRTGLP 1516
Query: 585 -DRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 643
++G PG + G G+ GF G G+ GP GPPG + G +G RG
Sbjct: 1517 GNQGEPGSKGQPGDSGEM-GFPGMAGL----------FGPKGPPGDI--GFKGIQGPRGP 1563
Query: 644 PGKMDK 649
PG M K
Sbjct: 1564 PGLMGK 1569
Score = 77.8 bits (190), Expect = 3e-14
Identities = 137/526 (26%), Positives = 174/526 (33%), Gaps = 106/526 (20%)
Query: 216 QQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA--PSQYSQQSSSYGQQSSF 273
+Q G G+ G++ G P P GS P Q
Sbjct: 992 EQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPG 1051
Query: 274 RQDHPSSMGVYGQES----GGFSGPGENRSMSGPDN-RGR-GRGGFDRGGMSRGGRGGGR 327
+ P G G+ G +G +R + GP +GR GR G +G G G R
Sbjct: 1052 SRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPG-QQGVAGERGHLGSR 1110
Query: 328 GGMG----AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGL-NDSVTLDDL 382
G G +G G PG P +GP +GPP + A+ GL ++ DL
Sbjct: 1111 GFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDL 1170
Query: 383 ADFFK--QCGVVKMNKRTG-----QPMIHIYLDKETGKP--------KGDATVSYEDPPT 427
+ G++ G PM L + G P KG + ED P
Sbjct: 1171 GPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPP 1230
Query: 428 AKAAVEWFDGKD----FQGSKLKVSLARKK--------------------PPMNSMRG-- 461
V G + QG K + K P RG
Sbjct: 1231 GPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSL 1290
Query: 462 ---GLPPREGRGMPPPLRGGPG-----GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGN 513
G P R G P L G G GP GP GP G G +G D P GP G RG
Sbjct: 1291 GPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRG- 1349
Query: 514 PSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGP 573
P G + GD PG Q + +P P +P P G +G GP
Sbjct: 1350 PVGDRGDRGEPGD-----PGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGP 1404
Query: 574 GGMRG-----------------------GRGGLMDRGGPGGM-FRGGRGGDRGGFRGGRG 609
G +G GR GL GP G+ R G+ G +G G
Sbjct: 1405 KGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQG--EQGDD 1462
Query: 610 MDRGGFG-GGRRGGPG--------GPPGPLMEQMGGRRGGRGGPGK 646
D G G G+RG PG GPPG + G G G PGK
Sbjct: 1463 GDPGPMGPAGKRGNPGVAGLPGAQGPPG--FKGESGLPGQLGPPGK 1506
Score = 69.7 bits (169), Expect = 8e-12
Identities = 122/440 (27%), Positives = 153/440 (34%), Gaps = 98/440 (22%)
Query: 278 PSSMGVYGQESG-GFSGPGENRSMSGP-----DNRGRGRGGFDRGGMSRGGRG--GGRGG 329
P +G G + GF GP G DN G G G RG G RG
Sbjct: 888 PGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKG------KPGARGLPGPRGQ 941
Query: 330 MGA-GERGGFNKPGGPMDEG----------PDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 378
+G G+ G PG P EG P LD G +P + + QG +
Sbjct: 942 LGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLD-GVKGEPGDPGRPGPVGEQGFMGFIG 1000
Query: 379 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY---EDPPTAKAAVEWF 435
L + G M G P + G P G T + PP ++
Sbjct: 1001 LVGEPGIVGEKGDRGMMGPPGVPGPKGSMG-HPGMPGGMGTPGEPGPQGPPGSRGPPGMR 1059
Query: 436 DGKDFQGSK-------LKVSLARKKPPMNSMRGGLPPREG----------RGMP------ 472
K +G + + S K PP R G P ++G RG P
Sbjct: 1060 GAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPS 1119
Query: 473 --PPLRG-----GPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAG 525
P +G GP GP GP GP G MG P+GP G+ G P G +
Sbjct: 1120 GPPGTKGLPGEPGPQGPQGPIGPPGEMG----------PKGPPGAVGEPGLPGEAGMKGD 1169
Query: 526 DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRG-- 581
P G Q Q P EG P P G GDRG GP G G +G
Sbjct: 1170 LGPLGTP--GEQGL-----IGQRGEPGLEGD-SGPMGPDGLKGDRGDPGPDGEHGEKGQE 1221
Query: 582 GLMDRGGP----------GGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGGPGGPP 627
GLM GP G + G+ G++G G +G +G G G GP G P
Sbjct: 1222 GLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTP 1281
Query: 628 GPLMEQMGGRRGGRGGPGKM 647
GP + G G G PG+M
Sbjct: 1282 GP--KGSRGSLGPTGAPGRM 1299
Score = 63.9 bits (154), Expect = 4e-10
Identities = 126/448 (28%), Positives = 153/448 (34%), Gaps = 102/448 (22%)
Query: 278 PSSMGVYGQESG-GFSG-PGENRSMSGPDNRGR----GRGGF-----------------D 314
P + G+ GQ GF G PG + P + GR G GF D
Sbjct: 954 PGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGD 1013
Query: 315 RGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGL 373
RG M G G +G MG G GG PG P GP GPP A +G
Sbjct: 1014 RGMMGPPGVPGPKGSMGHPGMPGGMGTPGEP---GPQ---GPPGSRGPPGMRGA---KGR 1064
Query: 374 NDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVE 433
D A G+ G+P G+P G V+ E
Sbjct: 1065 RGPRGPDGPAGEQGSRGLKGPPGPQGRP----------GRP-GQQGVAGERGHLGSRGFP 1113
Query: 434 WFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPRE-GRGMPPPLRGGPGGPGGPG-----G 487
G G L + P PP E G PP G PG PG G G
Sbjct: 1114 GIPGPS--GPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLG 1171
Query: 488 PMGRMGGRG-----------GDRGGFPPRGPRGSRGNPSGGGNVQHRA-----GDWQCPN 531
P+G G +G GD G P G +G RG+P G + G+ P
Sbjct: 1172 PLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPG 1231
Query: 532 PG-----------CGNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGG 579
P G Q RT K + + G + P GD G G G +G
Sbjct: 1232 PPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVP-----GDPGPPGTPGPKGS 1286
Query: 580 RGGLMDRGGPGGMFRGGRGGDRGGFRGGRGM-----------DRGGFG-GGRRGGPGGPP 627
RG L G PG M G G G+ G +G+ ++G G G+ GP GPP
Sbjct: 1287 RGSLGPTGAPGRMGAQGEPG-LAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPP 1345
Query: 628 GPLMEQMGGRRGGRGGPGKMDKGEHRQE 655
G G RG RG PG D G QE
Sbjct: 1346 GD--RGPVGDRGDRGEPG--DPGYPGQE 1369
Score = 46.6 bits (109), Expect = 7e-05
Identities = 83/323 (25%), Positives = 106/323 (32%), Gaps = 51/323 (15%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G P G + G + G+ YP Q G GQQ + HP
Sbjct: 1340 GPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKP--------GQQG--QPGHPGP 1389
Query: 281 MGVYGQE-SGGFSGP-GENRSMSGPDNRG-RGRGGFD--RGGMSRGGRGGGRGGMGAGER 335
G G + S G GP G+ P RG +G G RG + R G G G G R
Sbjct: 1390 RGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGR 1449
Query: 336 GGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMN 395
G + G ++G D D GP + + + G + Q G
Sbjct: 1450 DG--QAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKR 1507
Query: 396 KRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPP 455
G+ TG P + P D + + K PP
Sbjct: 1508 GTEGR----------TGLPGNQGEPGSKGQPG--------DSGEMGFPGMAGLFGPKGPP 1549
Query: 456 MNSMRGGLPPREGRGMPPPLRGGPG--------GPGGPGGPMGRMGGRGGDRGGFPPRGP 507
+ G+ G PP L G G GP G GP G G RG D G PRGP
Sbjct: 1550 GDIGFKGIQGPRG---PPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRG-DWGLQGPRGP 1605
Query: 508 RGSRGNPS----GGGNVQHRAGD 526
G RG P GG +Q + D
Sbjct: 1606 PGPRGRPGPPGPPGGPIQLQQDD 1628
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 90.5 bits (223), Expect = 4e-18
Identities = 133/488 (27%), Positives = 168/488 (34%), Gaps = 111/488 (22%)
Query: 194 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 253
P PP S ++ + + + + G+ + G + G + S G P P + G
Sbjct: 1285 PQGPPGSATAKGERGFPGAD-GRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPR 1343
Query: 254 SQA--PSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRG 311
P Q G R+ P G G G PG P +G
Sbjct: 1344 GPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPR-GPLGDPGPRGPPGLPGTAMKGDK 1402
Query: 312 GFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQ 371
G DRG RG G G GG+ GE G PG P +GP +GPP E D+
Sbjct: 1403 G-DRG--ERGPPGPGEGGIAPGEPGLPGLPGSPGPQGP---VGPPGKKGEKGDS------ 1450
Query: 372 GLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAA 431
G P + G+P PP A
Sbjct: 1451 -------------------------EDGAPGL-------PGQPGSPGEQGPRGPPGA--- 1475
Query: 432 VEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG--GPGGPGGPM 489
K +G + A +K RG P RG+ P + G PG GP GP GP
Sbjct: 1476 ---IGPKGDRGFPGPLGEAGEK----GERGPPGPAGSRGL-PGVAGRPGAKGPEGPPGPT 1527
Query: 490 GRMG-----GRGGDRGGFPP--RGPRGSRGN-----PSGGGNVQHRAGDWQCPNPGCGNQ 537
GR G GR GD P GP+G +G+ P G VQ G
Sbjct: 1528 GRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERG------------ 1575
Query: 538 NFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGR 597
P G + P P P GD G GP G+ G G D G PG GR
Sbjct: 1576 ---------------PPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGR 1620
Query: 598 GGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG-------KMDKG 650
G G G RG D G G GP G PG + G RG RG PG K D+G
Sbjct: 1621 PGPPGPV-GPRGRD-GEVGEKGDEGPPGDPG--LPGKAGERGLRGAPGVRGPVGEKGDQG 1676
Query: 651 EHRQERRD 658
+ ++ R+
Sbjct: 1677 DPGEDGRN 1684
Score = 83.6 bits (205), Expect = 5e-16
Identities = 140/520 (26%), Positives = 177/520 (34%), Gaps = 86/520 (16%)
Query: 157 PQSSTGGYNQPSL--GYGQSNYSYPQVPGSYPMQP-VTAPPSYPPTSYSSTQPTSYDQSS 213
P GG+ P G + + PQ P +P T PP T PT
Sbjct: 2175 PPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGR-----GLTGPTG----- 2224
Query: 214 YSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ--APSQYSQQSSSYGQQS 271
G P G G Q S G P Q G + AP + +
Sbjct: 2225 -----AVGLPGPPGPSGLVGPQGSPG------LPGQVGETGKPGAPGR---------DGA 2264
Query: 272 SFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR-GRGRGGFDRGGMSRGGRGGGRGGM 330
S + S GV G S G GP + GP G+ G +G GG G +
Sbjct: 2265 SGKDGDRGSPGVPG--SPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDL 2322
Query: 331 GA--GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQ 388
G +G PG ++G G P DP ED A +G FK
Sbjct: 2323 VGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKG-------------FKG 2369
Query: 389 CGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVS 448
V + G P G P + P A V F G+ ++
Sbjct: 2370 DPGVGVPGSPGPP----------GPPGVKGDLGLPGLPGAPGVVG-FPGQTGPRGEMG-- 2416
Query: 449 LARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRG-GFPPR 505
+P + RG P G+P PL GP GP G GP G G +G GD G G P
Sbjct: 2417 ----QPGPSGERGLAGPPGREGIPGPL--GPPGPPGSVGPPGASGLKGDKGDPGVGLP-- 2468
Query: 506 GPRGSRGNPS--GGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP 563
GPRG RG P G + G P + + +G P
Sbjct: 2469 GPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGP 2528
Query: 564 PG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFG 616
PG GD G GP G+ G +G D G PG G GD+G G G RG+
Sbjct: 2529 PGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQ 2588
Query: 617 GGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQER 656
G G PG P P + + G RG +G G M + ER
Sbjct: 2589 PGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGER 2628
Score = 83.2 bits (204), Expect = 7e-16
Identities = 143/496 (28%), Positives = 176/496 (35%), Gaps = 99/496 (19%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G+P G S G Q G PP + S AP Q S G+Q + P +
Sbjct: 1421 GEPGLPGLPGSPGPQGPVG--PPGKKGEKGDSEDGAPGLPGQPGSP-GEQGP--RGPPGA 1475
Query: 281 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-------G 333
+G G GF GP G RG RG GR G +G G G
Sbjct: 1476 IGPKGDR--GFPGPLGEAGEKG--ERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQG 1531
Query: 334 ERGGFNKPGGPMDEGPDL--DLGPPVDPDEDSDNSAIYVQGLN---------DSVTLDDL 382
E+G +PG P GP + G D A VQG D D
Sbjct: 1532 EKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDP 1591
Query: 383 ADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQ- 441
D G + + R G P ++G P PP G+D +
Sbjct: 1592 GDR----GPIGLTGRAGPP-------GDSGPPGEKGDPGRPGPPGPVGP----RGRDGEV 1636
Query: 442 GSKLKVSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPG--GPGGPGGPMGRMG--GRG 496
G K + PP + GLP + G RG LRG PG GP G G G G GR
Sbjct: 1637 GEK-----GDEGPPGDP---GLPGKAGERG----LRGAPGVRGPVGEKGDQGDPGEDGRN 1684
Query: 497 GDRGGFPPRGPRGSRGNPSGGGN-VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKP-- 553
G G P+G RG G P G V G + PG Q + + P
Sbjct: 1685 GSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGE 1744
Query: 554 ---EGFLPPPFPP-------PGGDRGRGGPGGMRG-----GRGGLMDRGGPGGMFRGGRG 598
EGF PP P P G++G GP G+ G G+ G GP G G+
Sbjct: 1745 RGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGA--AGKA 1802
Query: 599 GDRG-----GFRGGRGMDRGGFGGGRRGGPG--GPPGPLMEQMGGRRGGRGGPG------ 645
GD G G RG +G+ G G PG G PG + G+ G G PG
Sbjct: 1803 GDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPG-----LNGKNGEPGDPGEDGRKG 1857
Query: 646 -KMDKGEHRQERRDRP 660
K D G +E RD P
Sbjct: 1858 EKGDSGASGREGRDGP 1873
Score = 77.8 bits (190), Expect = 3e-14
Identities = 131/468 (27%), Positives = 163/468 (34%), Gaps = 81/468 (17%)
Query: 210 DQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQ 269
DQ + G P S G + G+ G P TG ++ + + +
Sbjct: 1674 DQGDPGEDGRNGSPGSSGPKGDRGEPGPPG---PPGRLVDTGPGAREKGEPGDRGQEGPR 1730
Query: 270 QSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGG 329
P + G G E GF GP GP D G G G RG
Sbjct: 1731 GPKGDPGLPGAPGERGIE--GFRGP------PGPQG--------DPGVRGPAGEKGDRGP 1774
Query: 330 MGAGERGGFN-KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQ 388
G R G + KPG GP+ G DP D QGL L +
Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834
Query: 389 CGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVS 448
G +N + G+P G P D E + + E DG + +
Sbjct: 1835 DGKPGLNGKNGEP----------GDPGEDGRKG-EKGDSGASGREGRDGPKGERGAPGI- 1882
Query: 449 LARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRGGFPPRG 506
L + PP GLP G PP +G PG PGG G G G G +G G P G
Sbjct: 1883 LGPQGPP------GLPGPVG----PPGQGFPGVPGGTGPKGDRGETGSKGEQ--GLP--G 1928
Query: 507 PRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP--P 564
RG RG P NV G + A R E + FLP P P
Sbjct: 1929 ERGLRGEPGSVPNVDRLLET-------AGIKASALR-EIVETWDESSGSFLPVPERRRGP 1980
Query: 565 GGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG--GDRG--GFRGGRGMDRGGFGGGRR 620
GD G GP G G G F G RG GDRG G +G G+ G G
Sbjct: 1981 KGDSGEQGPPGKEGPIG-----------FPGERGLKGDRGDPGPQGPPGLALGERGPPGP 2029
Query: 621 GGPGGPPG-PLMEQMGGRRGGRGGPGKM-------DKGEHRQERRDRP 660
G G PG P + + GR GG G G+ +KGE ++ RD P
Sbjct: 2030 SGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGP 2077
Score = 77.4 bits (189), Expect = 4e-14
Identities = 142/567 (25%), Positives = 193/567 (34%), Gaps = 113/567 (19%)
Query: 146 QDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQ 205
+DG K + S G + P G PQ P P PV P P T
Sbjct: 1852 EDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLP-GPVGPPGQGFPGVPGGTG 1910
Query: 206 PTSYDQSSYSQQNTYGQPSSYGQQSSYGQ-------------QSSYGQQPPTSYPPQTGS 252
P D+ + G P G + G ++S ++ ++ +GS
Sbjct: 1911 PKG-DRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGS 1969
Query: 253 YSQAPSQYSQQSSSYGQQSSFRQD----HPSSMGVYGQESG-GFSGP-----GENRSMSG 302
+ P + G+Q ++ P G+ G G GP GE R G
Sbjct: 1970 FLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGE-RGPPG 2028
Query: 303 PDNRGR--GRGGFD-----RGGMSRGGRGGGRGGMGA----GERGGFNKPGGPMDEGPDL 351
P G+ G GG+ GR G RG G GE+G PG P GP
Sbjct: 2029 PSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPG 2088
Query: 352 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET 411
GP V DE GL+ + G + G+P + +
Sbjct: 2089 PPGPKVSVDEPGP-------GLSG------------EQGPPGLKGAKGEPGSN----GDQ 2125
Query: 412 GKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGM 471
G PKGD V + DG + ++ KP + RG P G G
Sbjct: 2126 G-PKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGD 2184
Query: 472 PPP-----------------LRGGPGGPGGPG----GPMGRMGGRGGDRGGFPPRGPRGS 510
P P L+G PG G PG GP G +G G P GP G
Sbjct: 2185 PGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPG-------PPGPSGL 2237
Query: 511 RGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGR 570
G P G + + G + PG ++ A + ++ P P P P G +G
Sbjct: 2238 VG-PQGSPGLPGQVG--ETGKPGAPGRDGASGKDGDRGSPGVPGS---PGLPGPVGPKGE 2291
Query: 571 GGPGGMRGGR-----GGLMDRGGPGGMF-----RGGRGGDRG--GFRGGRGMDRGGFGGG 618
GP G G G ++G PGG+ G GDRG G RG +G G
Sbjct: 2292 PGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKG------EAG 2345
Query: 619 RRGGPGGPPGPLMEQMGGRRGGRGGPG 645
R G PG P + G +G +G PG
Sbjct: 2346 RAGEPGDPGEDGQKGAPGPKGFKGDPG 2372
Score = 76.6 bits (187), Expect = 7e-14
Identities = 116/387 (29%), Positives = 137/387 (35%), Gaps = 78/387 (20%)
Query: 295 GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA----GERG--GFNKPGGPMDEG 348
G+N P GR D G R GR G +G GA G +G G P GP +G
Sbjct: 1842 GKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQG 1901
Query: 349 -PDLD--LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI 405
P + GP D E QGL L G+P
Sbjct: 1902 FPGVPGGTGPKGDRGETGSKGE---QGLPGERGL------------------RGEPGSVP 1940
Query: 406 YLDK--ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL 463
+D+ ET K A + VE +D + GS L V R+ P +S G
Sbjct: 1941 NVDRLLETAGIKASAL---------REIVETWD--ESSGSFLPVPERRRGPKGDSGEQGP 1989
Query: 464 PPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 523
P +EG P RG G G PG P G G G+RG P G G G P G
Sbjct: 1990 PGKEGPIGFPGERGLKGDRGDPG-PQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRA 2048
Query: 524 AGDWQCPNPGCGNQ--NFAWRTECNQCKAPKPEGFLPPPFPP------------------ 563
G + PG + R E + P G PP PP
Sbjct: 2049 GGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQG 2108
Query: 564 PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGG 618
P G +G G G G +G DRG PG G G RG G G RGM G G
Sbjct: 2109 PPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGM-AGPEGKP 2167
Query: 619 RRGGPGGPPGPLMEQMGGRRGGRGGPG 645
GP GPPGP+ GG G PG
Sbjct: 2168 GLQGPRGPPGPV--------GGHGDPG 2186
Score = 75.9 bits (185), Expect = 1e-13
Identities = 146/532 (27%), Positives = 183/532 (34%), Gaps = 114/532 (21%)
Query: 172 GQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQ--SSYSQQNTYGQPSSYGQQ 229
G S P +PG P P P PP + + ++ G P G +
Sbjct: 1448 GDSEDGAPGLPGQ-PGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSR 1506
Query: 230 SSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG 289
G G + P P TG + G+ P+ G G++
Sbjct: 1507 GLPGVAGRPGAKGPEGPPGPTGRQGE--------KGEPGRPGDPAVVGPAVAGPKGEK-- 1556
Query: 290 GFSGPGENRSMSG------------PDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-GERG 336
G GP R +G P + G DRG + GR G G G GE+G
Sbjct: 1557 GDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKG 1616
Query: 337 GFNKPG--GPM-------------DEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDD 381
+PG GP+ DEGP D G P E A V+G + +
Sbjct: 1617 DPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRG-----PVGE 1671
Query: 382 LADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQ 441
D G + R G P + PKGD P + V+ G
Sbjct: 1672 KGD----QGDPGEDGRNGSP--------GSSGPKGDRGEPGPPGPPGR-LVDTGPG---- 1714
Query: 442 GSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG-----GPGGPMGRMGGRG 496
AR+K RG PR +G P L G PG G GP GP G G RG
Sbjct: 1715 --------AREKGEPGD-RGQEGPRGPKG-DPGLPGAPGERGIEGFRGPPGPQGDPGVRG 1764
Query: 497 --GDRGGFPPRGPRGSRG--------NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECN 546
G++G P G G G PSG +AGD PG +
Sbjct: 1765 PAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGD-----PG-----------RD 1808
Query: 547 QCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF 604
+ E LP P PPG G G G G+ G G + G PG R G GD G
Sbjct: 1809 GLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNG---EPGDPGEDGRKGEKGDSGAS 1865
Query: 605 -RGGRGMDRGGFGGGRRGGPGGP---PGPLMEQMGGRRGGRGGPG-KMDKGE 651
R GR +G G GP GP PGP+ G G GG G K D+GE
Sbjct: 1866 GREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGE 1917
Score = 71.2 bits (173), Expect = 3e-12
Identities = 113/399 (28%), Positives = 142/399 (35%), Gaps = 84/399 (21%)
Query: 278 PSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDR----GGMSRGGRGGGRGGMG-- 331
P G G+ G GP R ++GP R G G + G G +G G
Sbjct: 2406 PGQTGPRGEM--GQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDP 2463
Query: 332 ----------AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN----DSV 377
GE G + G P EGP GPP E + + GL DS
Sbjct: 2464 GVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSA 2523
Query: 378 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDG 437
+ L + M +R + LD + G P+GD DP
Sbjct: 2524 VI--LGPPGPRGAKGDMGERGPRG-----LDGDKG-PRGDNG----DP------------ 2559
Query: 438 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG---- 493
G K K P + GLP G P G G PG PG P G+ G
Sbjct: 2560 ----GDK-----GSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSP-GKDGVPGI 2609
Query: 494 -GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG----CGNQNFAWRTEC-NQ 547
G GD G PRG +G RG G + + PG G++ Q
Sbjct: 2610 RGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQ 2669
Query: 548 CKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGG 607
AP EG + P GDRG G G +G +G +RG PG GGF G
Sbjct: 2670 SGAPGKEGLIGPK-----GDRGFDGQPGPKGDQGEKGERGTPG----------IGGFPGP 2714
Query: 608 RGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 646
G D G G G GP GP E + G++G RG PG+
Sbjct: 2715 SGND-GSAGPPGPPGSVGPRGP--EGLQGQKGERGPPGE 2750
Score = 64.3 bits (155), Expect = 3e-10
Identities = 68/190 (35%), Positives = 76/190 (40%), Gaps = 28/190 (14%)
Query: 465 PREGRGMPPP--LRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNV 520
P+ +G P LRG G PG PG P GR G G G G +G RG G G+
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLP-GRTGAPGPQGPPGSATAKGERGFPGADGRPGS- 1309
Query: 521 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 580
RAG NPG AP +G P P P GD G GP G +G
Sbjct: 1310 PGRAG-----NPGTPG-------------APGLKG--SPGLPGPRGDPGERGPRGPKGEP 1349
Query: 581 GGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGG 640
G G G GR GD G G RG G GP G PG M+ G RG
Sbjct: 1350 GAPGQVIGGEGPGLPGRKGDPGP--SGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGE 1407
Query: 641 RGGPGKMDKG 650
RG PG + G
Sbjct: 1408 RGPPGPGEGG 1417
Score = 56.2 bits (134), Expect = 9e-08
Identities = 108/397 (27%), Positives = 137/397 (34%), Gaps = 67/397 (16%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
GQP G++ G G P P GS + S G + P
Sbjct: 2416 GQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGA-----SGLKGDKGDPGVGLPGP 2470
Query: 281 MGVYGQES--GGFSGPGEN--RSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA---- 332
G G+ G PG+ R ++GP RG ++G + G G +G
Sbjct: 2471 RGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERG--EKGDVGSAGLKGDKGDSAVILGP 2528
Query: 333 -GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK---Q 388
G RG G G D D GP D + D + G S L L Q
Sbjct: 2529 PGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQ 2588
Query: 389 CGVVKMNKRTGQPMIHIYLDKETGKP-----KGDATVSYEDPPTAKA--AVEWFDGKDFQ 441
G + G P + G P KGD V + P K V+ G D +
Sbjct: 2589 PGAAGIPGDPGSP-------GKDGVPGIRGEKGD--VGFMGPRGLKGERGVKGACGLDGE 2639
Query: 442 -------GSKLKVSLARKKPPMNSM----RGGLPPREGRGMPPPLRGGPGGPGGPGGPMG 490
G + LA K M + G P +EG P RG G PG P G G
Sbjct: 2640 KGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPG-PKGDQG 2698
Query: 491 RMGGRGGDR-GGFP-PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 548
G RG GGFP P G GS G P G+V R + G Q
Sbjct: 2699 EKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPE------GLQGQKGE-------- 2744
Query: 549 KAPKPEGFLPPPFPP--PG--GDRGRGGPGGMRGGRG 581
+ P E + P P PG G++GR GP G RG +G
Sbjct: 2745 RGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKG 2781
Score = 50.4 bits (119), Expect = 5e-06
Identities = 38/101 (37%), Positives = 44/101 (43%), Gaps = 8/101 (7%)
Query: 551 PKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFR 605
P+PE P P P G +G G G+RG G D G PG G G G G R
Sbjct: 1242 PRPE---PCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGER 1298
Query: 606 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 646
G G D GR G PG P P ++ G G RG PG+
Sbjct: 1299 GFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGE 1339
Score = 33.9 bits (76), Expect = 0.49
Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 12/100 (12%)
Query: 289 GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEG 348
GGF GP N +GP G RG G+ G RG G G PG P + G
Sbjct: 2709 GGFPGPSGNDGSAGPPGPPGSVG--PRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERG 2766
Query: 349 PDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQ 388
G P P + +A+ T DD+ F +Q
Sbjct: 2767 EQGRPG-PAGPRGEKGEAAL---------TEDDIRGFVRQ 2796
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
[Homo sapiens]
Length = 1650
Score = 87.8 bits (216), Expect = 3e-17
Identities = 117/397 (29%), Positives = 153/397 (38%), Gaps = 71/397 (17%)
Query: 278 PSSMGVYGQESG--GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG---- 331
P S G+ G ESG G GP + ++GP + RG R G G RG G
Sbjct: 418 PGSPGLKG-ESGDLGPQGPRGPQGLTGPPGKAGRRG--------RAGADGARGMPGDPGV 468
Query: 332 AGERGGFNKPGGPMDEGPDLDLG------PPVDPDEDSDNSAIYVQGLNDSVTLDDLADF 385
G+RG PG P ++G D G PP + E D+ I +GL L
Sbjct: 469 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 528
Query: 386 FKQCGV-----VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDF 440
G+ V+ P + E G P T + P + A+ K
Sbjct: 529 KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 588
Query: 441 QGSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG-- 496
QG KP + M G G P G+ PP +G G P GP GP+G G RG
Sbjct: 589 QG----------KPGLPGMPGSDGPPGHPGKEGPPGTKGNQG-PSGPQGPLGYPGPRGVK 637
Query: 497 ---GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKP 553
G RG +G +G G P G++ + + PG ++ P
Sbjct: 638 GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-------------GP 684
Query: 554 EGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRG 609
EG P G G G GP G+ G +G L G PG R G G G GF G G
Sbjct: 685 EG-------PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASG 737
Query: 610 MDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 646
++G G + GP G GP + G+RG RG GK
Sbjct: 738 -EKGARGLSGKSGPRGERGPTGPR--GQRGPRGATGK 771
Score = 86.3 bits (212), Expect = 8e-17
Identities = 148/565 (26%), Positives = 193/565 (34%), Gaps = 91/565 (16%)
Query: 142 PTRP--QDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPT 199
PT P Q G + T G + P G+ PQ P +P PP P
Sbjct: 756 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK--GPPGPPGK 813
Query: 200 SYSSTQPTSYDQSSYS-QQNTYGQPSSYGQQSSYGQQSSYGQQP---PTSYPPQTGSYSQ 255
P + + + G P G Q + G+ G++ P P + G
Sbjct: 814 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 873
Query: 256 APSQYSQQSSSYGQQSSFRQDHPSSM-GVYGQES--GGFSGPG--ENRSMSGPDNRGRGR 310
A + ++ G + +D P+ + G G+ G GPG N SGP
Sbjct: 874 AGKEGTKGDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 931
Query: 311 GGFDRGGMSRGG------RGGGRGGMGA-------GERGGFNKPGGPMDEGP---DLDLG 354
G +RG GG R G +G GA GE+G G +GP G
Sbjct: 932 G--ERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 989
Query: 355 PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP 414
PP ED D + G + K NK P G+P
Sbjct: 990 PPGVAGEDGDKGEVGDPGQKGT----------------KGNKGEHGPPGPPGPIGPVGQP 1033
Query: 415 KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRG---- 470
+ P A+ F K +G++ PP GLP G
Sbjct: 1034 ---GAAGADGEPGARGPQGHFGAKGDEGTR-----GFNGPPGPIGLQGLPGPSGEKGETG 1085
Query: 471 ----MPPPLRGGPGGPGGPG---GPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGG 518
M PP GP GP GP GP G GG G G++G G G +G P G
Sbjct: 1086 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1145
Query: 519 NVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKA-PKPEGFLPPPFPP----------PGG 566
R + PG G T + K P P GF P PP G
Sbjct: 1146 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKG 1205
Query: 567 DRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGG 622
DRG G G G G + G PG + + G G G G +GG+G D G G + G
Sbjct: 1206 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265
Query: 623 PGGPPGPLMEQMGGRRGGRGGPGKM 647
P GP GP + G G RG PG +
Sbjct: 1266 PVGPAGPAGKP--GPDGLRGLPGSV 1288
Score = 78.6 bits (192), Expect = 2e-14
Identities = 133/469 (28%), Positives = 168/469 (35%), Gaps = 101/469 (21%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQSSFRQD 276
G P S G+ G + G+ PT P G + Y G + S
Sbjct: 674 GVPGSRGED---GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL--G 728
Query: 277 HPSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA 332
P G G++ G SGP R +GP + RG + G G GG G G
Sbjct: 729 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK--GTSGGDGPHGP 786
Query: 333 GERGGFNKPGGPMD-EGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 391
G P GP GP GPP P +D L Q G
Sbjct: 787 PGERGLPGPQGPNGFPGPK---GPPGPPGKDG------------------LPGHPGQRGE 825
Query: 392 VKMNKRTGQPMIHIYLDK-----ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 446
V +TG P + ETG P G+ P + + GK+ G+K
Sbjct: 826 VGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKE--GTK-- 880
Query: 447 VSLARKKPPMNSMRGGLPPREG----RGMP-----PPLRGGPG-----GPGGPGGPMGRM 492
PP G P ++G RG P P GGPG GP GP GP G
Sbjct: 881 ---GDPGPP------GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 931
Query: 493 GGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 550
G RG G G P G G +G P AG+ P G + T + +
Sbjct: 932 GERGAAGSGGPIGPPGRPGPQGPPGA-------AGEKGVP----GEKGPIGPTGRDGVQG 980
Query: 551 PKPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--- 602
P LP P PPG GD+G G G +G +G + G PG G G G
Sbjct: 981 PVG---LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1037
Query: 603 --GFRGGRGMDRGGFGG-GRRG--GPGGPPGPL-MEQMGGRRGGRGGPG 645
G G RG +G FG G G G GPPGP+ ++ + G G +G G
Sbjct: 1038 ADGEPGARG-PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1085
Score = 73.9 bits (180), Expect = 4e-13
Identities = 118/440 (26%), Positives = 150/440 (34%), Gaps = 103/440 (23%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ-QSSSYGQQSSFRQDHPS 279
G G G + + G+ P P G Q + + + + G Q F
Sbjct: 998 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF------ 1051
Query: 280 SMGVYGQE-SGGFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGG 337
G G E + GF+GP + G P G D G M G G RG G G
Sbjct: 1052 --GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN---G 1106
Query: 338 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 397
+ P GP G +LGPP + E ++ + +QG + GV
Sbjct: 1107 ADGPQGP--PGGVGNLGPPGEKGEPGESGSPGIQG---------------EPGVKGPRGE 1149
Query: 398 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 457
G+ KG++ E P DG P N
Sbjct: 1150 RGE--------------KGESGQPGEPGPPGPKGPTGDDG----------------PKGN 1179
Query: 458 SMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSRG 512
G P G PP GGP G G G G G G G G P GP G RG
Sbjct: 1180 PGPVGFPGDPG----PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG 1235
Query: 513 NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGG 572
G+ + G +PG AP G + P G G+ G
Sbjct: 1236 PAGSPGSEGRQGGKGAKGDPGA-------------IGAPGKTGPVGP-----AGPAGKPG 1277
Query: 573 PGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG-----G 625
P G+RG G + +G PG + G G G G G RG D G G +G PG G
Sbjct: 1278 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRG-DAG--AKGEKGHPGLIGLIG 1334
Query: 626 PPGPLMEQMGGRRGGRGGPG 645
PPG EQ G +G RG PG
Sbjct: 1335 PPG---EQ--GEKGDRGLPG 1349
Score = 64.7 bits (156), Expect = 3e-10
Identities = 73/223 (32%), Positives = 83/223 (37%), Gaps = 35/223 (15%)
Query: 449 LARKKPPMNSMRGGLPPREGRGMPPPLRGGPG--GPGGPGGPMGRMG--GRGGDRG---- 500
LA + PP G P G+ P L+G G GP GP GP G G G+ G RG
Sbjct: 397 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 456
Query: 501 ----GFPP----RGPRGSRGNPSGGGNVQHRA--GDWQCPNPGCGNQNFAWRTECNQCKA 550
G P +G RG G P G HR G P P + E
Sbjct: 457 DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 516
Query: 551 PK---PEGFL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGG 603
P P G L PP P P G RG GP G +G G + G PG G G G
Sbjct: 517 PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG- 575
Query: 604 FRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 646
+G G GP G PG + M G G G PGK
Sbjct: 576 -------PQGAIGPHGEKGPQGKPG--LPGMPGSDGPPGHPGK 609
Score = 57.8 bits (138), Expect = 3e-08
Identities = 70/215 (32%), Positives = 81/215 (37%), Gaps = 42/215 (19%)
Query: 472 PPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQC 529
P L GP GP GP G +G G G G G RGP G G P G
Sbjct: 307 PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 366
Query: 530 P---NPGCGNQNFAWRTECNQCKA------------PKPEGFL--PPPFPPPG-----GD 567
P G G++ + Q +A P P G+ P P PG G+
Sbjct: 367 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 426
Query: 568 RGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG----- 617
G GP G RG +G G G R G G RG G +G RG D G G
Sbjct: 427 SGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFD--GLPGLPGEK 484
Query: 618 GRRGGPG-----GPPGPLMEQ-MGGRRGGRGGPGK 646
G RG G GPPG E+ G G RG PG+
Sbjct: 485 GHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 519
Score = 56.6 bits (135), Expect = 7e-08
Identities = 108/442 (24%), Positives = 141/442 (31%), Gaps = 65/442 (14%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 279
G+P + G Q +G + G + P G PS ++ G P
Sbjct: 1040 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1099
Query: 280 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-GERGGF 338
G PG ++ P +G G G G RG G GE G
Sbjct: 1100 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1159
Query: 339 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 389
+PG P +GP D GP P DP + G D
Sbjct: 1160 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDG-------- 1211
Query: 390 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 449
GQP TG+ + P + + GK +G +
Sbjct: 1212 -------EPGQPGS----PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1260
Query: 450 ARKKPPMNSMR-GGLPPREG-RGMPPPL--RGGPG-----GPGGPGGPMGRMGGRGGDRG 500
K P+ G P +G RG+P + +G PG GP GP GP G G RG
Sbjct: 1261 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD--- 1317
Query: 501 GFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 555
G +G +G+P G Q GD P P G+ P G
Sbjct: 1318 ----AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ-GSPGQKGEMGIPGASGPIGPG 1372
Query: 556 FLPPPFPPPGGDRGR------GGPGGMRGGRGGLMDRGGPGGMFR----GGRGGDRGGFR 605
PP P P G +G GGP G +G +G G PG + + R
Sbjct: 1373 G-PPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD 1431
Query: 606 GGRGM--DRGGFGGGRRGGPGG 625
G R M D GG G PGG
Sbjct: 1432 GSRLMQEDEAIPTGGAPGSPGG 1453
Score = 49.7 bits (117), Expect = 9e-06
Identities = 71/236 (30%), Positives = 83/236 (35%), Gaps = 67/236 (28%)
Query: 454 PPMNSMRGGLPPREG-RGMPPPLRGGP--GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGS 510
PP+ G +G +G P L G GP GP GP G +G P G
Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIG-------------PPGI 329
Query: 511 RGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEG---FLPPPFPPPGGD 567
+GNP G+ R + PG AP P G LP F GGD
Sbjct: 330 QGNPGPVGDPGERGPPGRAGLPGSDG-------------APGPPGTSLMLPFRFGSGGGD 376
Query: 568 RG---------------------RGGPG--GMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 602
+G RG PG G G G L G PG G GD G
Sbjct: 377 KGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG---LKGESGDLGPQ 433
Query: 603 GFRGGRGMDRGGFGGGRRG-----GPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHR 653
G RG +G+ GRRG G G PG + G RG G PG + HR
Sbjct: 434 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGD--PGVKGDRGFDGLPGLPGEKGHR 487
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
[Homo sapiens]
Length = 1629
Score = 87.8 bits (216), Expect = 3e-17
Identities = 117/397 (29%), Positives = 153/397 (38%), Gaps = 71/397 (17%)
Query: 278 PSSMGVYGQESG--GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG---- 331
P S G+ G ESG G GP + ++GP + RG R G G RG G
Sbjct: 397 PGSPGLKG-ESGDLGPQGPRGPQGLTGPPGKAGRRG--------RAGADGARGMPGDPGV 447
Query: 332 AGERGGFNKPGGPMDEGPDLDLG------PPVDPDEDSDNSAIYVQGLNDSVTLDDLADF 385
G+RG PG P ++G D G PP + E D+ I +GL L
Sbjct: 448 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 507
Query: 386 FKQCGV-----VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDF 440
G+ V+ P + E G P T + P + A+ K
Sbjct: 508 KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 567
Query: 441 QGSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG-- 496
QG KP + M G G P G+ PP +G G P GP GP+G G RG
Sbjct: 568 QG----------KPGLPGMPGSDGPPGHPGKEGPPGTKGNQG-PSGPQGPLGYPGPRGVK 616
Query: 497 ---GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKP 553
G RG +G +G G P G++ + + PG ++ P
Sbjct: 617 GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-------------GP 663
Query: 554 EGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRG 609
EG P G G G GP G+ G +G L G PG R G G G GF G G
Sbjct: 664 EG-------PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASG 716
Query: 610 MDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 646
++G G + GP G GP + G+RG RG GK
Sbjct: 717 -EKGARGLSGKSGPRGERGPTGPR--GQRGPRGATGK 750
Score = 86.3 bits (212), Expect = 8e-17
Identities = 148/565 (26%), Positives = 193/565 (34%), Gaps = 91/565 (16%)
Query: 142 PTRP--QDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPT 199
PT P Q G + T G + P G+ PQ P +P PP P
Sbjct: 735 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK--GPPGPPGK 792
Query: 200 SYSSTQPTSYDQSSYS-QQNTYGQPSSYGQQSSYGQQSSYGQQP---PTSYPPQTGSYSQ 255
P + + + G P G Q + G+ G++ P P + G
Sbjct: 793 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 852
Query: 256 APSQYSQQSSSYGQQSSFRQDHPSSM-GVYGQES--GGFSGPG--ENRSMSGPDNRGRGR 310
A + ++ G + +D P+ + G G+ G GPG N SGP
Sbjct: 853 AGKEGTKGDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 910
Query: 311 GGFDRGGMSRGG------RGGGRGGMGA-------GERGGFNKPGGPMDEGP---DLDLG 354
G +RG GG R G +G GA GE+G G +GP G
Sbjct: 911 G--ERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 968
Query: 355 PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP 414
PP ED D + G + K NK P G+P
Sbjct: 969 PPGVAGEDGDKGEVGDPGQKGT----------------KGNKGEHGPPGPPGPIGPVGQP 1012
Query: 415 KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRG---- 470
+ P A+ F K +G++ PP GLP G
Sbjct: 1013 ---GAAGADGEPGARGPQGHFGAKGDEGTR-----GFNGPPGPIGLQGLPGPSGEKGETG 1064
Query: 471 ----MPPPLRGGPGGPGGPG---GPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGG 518
M PP GP GP GP GP G GG G G++G G G +G P G
Sbjct: 1065 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1124
Query: 519 NVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKA-PKPEGFLPPPFPP----------PGG 566
R + PG G T + K P P GF P PP G
Sbjct: 1125 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKG 1184
Query: 567 DRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGG 622
DRG G G G G + G PG + + G G G G +GG+G D G G + G
Sbjct: 1185 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1244
Query: 623 PGGPPGPLMEQMGGRRGGRGGPGKM 647
P GP GP + G G RG PG +
Sbjct: 1245 PVGPAGPAGKP--GPDGLRGLPGSV 1267
Score = 78.6 bits (192), Expect = 2e-14
Identities = 133/469 (28%), Positives = 168/469 (35%), Gaps = 101/469 (21%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQSSFRQD 276
G P S G+ G + G+ PT P G + Y G + S
Sbjct: 653 GVPGSRGED---GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL--G 707
Query: 277 HPSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA 332
P G G++ G SGP R +GP + RG + G G GG G G
Sbjct: 708 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK--GTSGGDGPHGP 765
Query: 333 GERGGFNKPGGPMD-EGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 391
G P GP GP GPP P +D L Q G
Sbjct: 766 PGERGLPGPQGPNGFPGPK---GPPGPPGKDG------------------LPGHPGQRGE 804
Query: 392 VKMNKRTGQPMIHIYLDK-----ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 446
V +TG P + ETG P G+ P + + GK+ G+K
Sbjct: 805 VGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKE--GTK-- 859
Query: 447 VSLARKKPPMNSMRGGLPPREG----RGMP-----PPLRGGPG-----GPGGPGGPMGRM 492
PP G P ++G RG P P GGPG GP GP GP G
Sbjct: 860 ---GDPGPP------GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 910
Query: 493 GGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 550
G RG G G P G G +G P AG+ P G + T + +
Sbjct: 911 GERGAAGSGGPIGPPGRPGPQGPPGA-------AGEKGVP----GEKGPIGPTGRDGVQG 959
Query: 551 PKPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--- 602
P LP P PPG GD+G G G +G +G + G PG G G G
Sbjct: 960 PVG---LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1016
Query: 603 --GFRGGRGMDRGGFGG-GRRG--GPGGPPGPL-MEQMGGRRGGRGGPG 645
G G RG +G FG G G G GPPGP+ ++ + G G +G G
Sbjct: 1017 ADGEPGARG-PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1064
Score = 73.9 bits (180), Expect = 4e-13
Identities = 118/440 (26%), Positives = 150/440 (34%), Gaps = 103/440 (23%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ-QSSSYGQQSSFRQDHPS 279
G G G + + G+ P P G Q + + + + G Q F
Sbjct: 977 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF------ 1030
Query: 280 SMGVYGQE-SGGFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGG 337
G G E + GF+GP + G P G D G M G G RG G G
Sbjct: 1031 --GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN---G 1085
Query: 338 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 397
+ P GP G +LGPP + E ++ + +QG + GV
Sbjct: 1086 ADGPQGP--PGGVGNLGPPGEKGEPGESGSPGIQG---------------EPGVKGPRGE 1128
Query: 398 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 457
G+ KG++ E P DG P N
Sbjct: 1129 RGE--------------KGESGQPGEPGPPGPKGPTGDDG----------------PKGN 1158
Query: 458 SMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSRG 512
G P G PP GGP G G G G G G G G P GP G RG
Sbjct: 1159 PGPVGFPGDPG----PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG 1214
Query: 513 NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGG 572
G+ + G +PG AP G + P G G+ G
Sbjct: 1215 PAGSPGSEGRQGGKGAKGDPGA-------------IGAPGKTGPVGP-----AGPAGKPG 1256
Query: 573 PGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG-----G 625
P G+RG G + +G PG + G G G G G RG D G G +G PG G
Sbjct: 1257 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRG-DAG--AKGEKGHPGLIGLIG 1313
Query: 626 PPGPLMEQMGGRRGGRGGPG 645
PPG EQ G +G RG PG
Sbjct: 1314 PPG---EQ--GEKGDRGLPG 1328
Score = 64.7 bits (156), Expect = 3e-10
Identities = 73/223 (32%), Positives = 83/223 (37%), Gaps = 35/223 (15%)
Query: 449 LARKKPPMNSMRGGLPPREGRGMPPPLRGGPG--GPGGPGGPMGRMG--GRGGDRG---- 500
LA + PP G P G+ P L+G G GP GP GP G G G+ G RG
Sbjct: 376 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 435
Query: 501 ----GFPP----RGPRGSRGNPSGGGNVQHRA--GDWQCPNPGCGNQNFAWRTECNQCKA 550
G P +G RG G P G HR G P P + E
Sbjct: 436 DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 495
Query: 551 PK---PEGFL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGG 603
P P G L PP P P G RG GP G +G G + G PG G G G
Sbjct: 496 PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG- 554
Query: 604 FRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 646
+G G GP G PG + M G G G PGK
Sbjct: 555 -------PQGAIGPHGEKGPQGKPG--LPGMPGSDGPPGHPGK 588
Score = 57.8 bits (138), Expect = 3e-08
Identities = 70/215 (32%), Positives = 81/215 (37%), Gaps = 42/215 (19%)
Query: 472 PPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQC 529
P L GP GP GP G +G G G G G RGP G G P G
Sbjct: 286 PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 345
Query: 530 P---NPGCGNQNFAWRTECNQCKA------------PKPEGFL--PPPFPPPG-----GD 567
P G G++ + Q +A P P G+ P P PG G+
Sbjct: 346 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 405
Query: 568 RGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG----- 617
G GP G RG +G G G R G G RG G +G RG D G G
Sbjct: 406 SGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFD--GLPGLPGEK 463
Query: 618 GRRGGPG-----GPPGPLMEQ-MGGRRGGRGGPGK 646
G RG G GPPG E+ G G RG PG+
Sbjct: 464 GHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 498
Score = 56.6 bits (135), Expect = 7e-08
Identities = 108/442 (24%), Positives = 141/442 (31%), Gaps = 65/442 (14%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 279
G+P + G Q +G + G + P G PS ++ G P
Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078
Query: 280 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-GERGGF 338
G PG ++ P +G G G G RG G GE G
Sbjct: 1079 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1138
Query: 339 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 389
+PG P +GP D GP P DP + G D
Sbjct: 1139 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDG-------- 1190
Query: 390 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 449
GQP TG+ + P + + GK +G +
Sbjct: 1191 -------EPGQPGS----PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1239
Query: 450 ARKKPPMNSMR-GGLPPREG-RGMPPPL--RGGPG-----GPGGPGGPMGRMGGRGGDRG 500
K P+ G P +G RG+P + +G PG GP GP GP G G RG
Sbjct: 1240 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD--- 1296
Query: 501 GFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 555
G +G +G+P G Q GD P P G+ P G
Sbjct: 1297 ----AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ-GSPGQKGEMGIPGASGPIGPG 1351
Query: 556 FLPPPFPPPGGDRGR------GGPGGMRGGRGGLMDRGGPGGMFR----GGRGGDRGGFR 605
PP P P G +G GGP G +G +G G PG + + R
Sbjct: 1352 G-PPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD 1410
Query: 606 GGRGM--DRGGFGGGRRGGPGG 625
G R M D GG G PGG
Sbjct: 1411 GSRLMQEDEAIPTGGAPGSPGG 1432
Score = 50.8 bits (120), Expect = 4e-06
Identities = 66/220 (30%), Positives = 79/220 (35%), Gaps = 47/220 (21%)
Query: 468 GRGMPPPLRGGPGGPGGPGGP------MGRMGGRGGDRGGF------------------- 502
G PP G PG G PG P R G GGD+G
Sbjct: 319 GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLAL 378
Query: 503 -PPRGPRGSRGNPS-----GGGNVQHRAGDW-----QCPNPGCGNQNFAWRTECNQCKAP 551
P GP G G P G ++ +GD + P G A R + A
Sbjct: 379 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRR--GRAGAD 436
Query: 552 KPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRG 609
G P P GDRG G G+ G +G D G G G G+RG G G RG
Sbjct: 437 GARGM--PGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG 494
Query: 610 MDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGPG 645
+ G G GP GPPG P + M G +G +G G
Sbjct: 495 LP-GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLG 533
Score = 35.4 bits (80), Expect = 0.17
Identities = 40/122 (32%), Positives = 45/122 (36%), Gaps = 28/122 (22%)
Query: 555 GFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMD--- 611
G L P P G G GP G++G G + D G G R G G G G G
Sbjct: 287 GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGA-PGPPGTSLML 345
Query: 612 --RGGFGGGRRG-------------------GPGGPPGPLMEQMGGRRGGRGGPGKMD-K 649
R G GGG +G GPPGP+ GR G G PG K
Sbjct: 346 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM--GYTGRPGPLGQPGSPGLK 403
Query: 650 GE 651
GE
Sbjct: 404 GE 405
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
[Homo sapiens]
Length = 1736
Score = 87.8 bits (216), Expect = 3e-17
Identities = 117/397 (29%), Positives = 153/397 (38%), Gaps = 71/397 (17%)
Query: 278 PSSMGVYGQESG--GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG---- 331
P S G+ G ESG G GP + ++GP + RG R G G RG G
Sbjct: 504 PGSPGLKG-ESGDLGPQGPRGPQGLTGPPGKAGRRG--------RAGADGARGMPGDPGV 554
Query: 332 AGERGGFNKPGGPMDEGPDLDLG------PPVDPDEDSDNSAIYVQGLNDSVTLDDLADF 385
G+RG PG P ++G D G PP + E D+ I +GL L
Sbjct: 555 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 614
Query: 386 FKQCGV-----VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDF 440
G+ V+ P + E G P T + P + A+ K
Sbjct: 615 KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 674
Query: 441 QGSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG-- 496
QG KP + M G G P G+ PP +G G P GP GP+G G RG
Sbjct: 675 QG----------KPGLPGMPGSDGPPGHPGKEGPPGTKGNQG-PSGPQGPLGYPGPRGVK 723
Query: 497 ---GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKP 553
G RG +G +G G P G++ + + PG ++ P
Sbjct: 724 GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-------------GP 770
Query: 554 EGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRG 609
EG P G G G GP G+ G +G L G PG R G G G GF G G
Sbjct: 771 EG-------PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASG 823
Query: 610 MDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 646
++G G + GP G GP + G+RG RG GK
Sbjct: 824 -EKGARGLSGKSGPRGERGPTGPR--GQRGPRGATGK 857
Score = 86.3 bits (212), Expect = 8e-17
Identities = 148/565 (26%), Positives = 193/565 (34%), Gaps = 91/565 (16%)
Query: 142 PTRP--QDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPT 199
PT P Q G + T G + P G+ PQ P +P PP P
Sbjct: 842 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK--GPPGPPGK 899
Query: 200 SYSSTQPTSYDQSSYS-QQNTYGQPSSYGQQSSYGQQSSYGQQP---PTSYPPQTGSYSQ 255
P + + + G P G Q + G+ G++ P P + G
Sbjct: 900 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 959
Query: 256 APSQYSQQSSSYGQQSSFRQDHPSSM-GVYGQES--GGFSGPG--ENRSMSGPDNRGRGR 310
A + ++ G + +D P+ + G G+ G GPG N SGP
Sbjct: 960 AGKEGTKGDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 1017
Query: 311 GGFDRGGMSRGG------RGGGRGGMGA-------GERGGFNKPGGPMDEGP---DLDLG 354
G +RG GG R G +G GA GE+G G +GP G
Sbjct: 1018 G--ERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 1075
Query: 355 PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP 414
PP ED D + G + K NK P G+P
Sbjct: 1076 PPGVAGEDGDKGEVGDPGQKGT----------------KGNKGEHGPPGPPGPIGPVGQP 1119
Query: 415 KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRG---- 470
+ P A+ F K +G++ PP GLP G
Sbjct: 1120 ---GAAGADGEPGARGPQGHFGAKGDEGTR-----GFNGPPGPIGLQGLPGPSGEKGETG 1171
Query: 471 ----MPPPLRGGPGGPGGPG---GPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGG 518
M PP GP GP GP GP G GG G G++G G G +G P G
Sbjct: 1172 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1231
Query: 519 NVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKA-PKPEGFLPPPFPP----------PGG 566
R + PG G T + K P P GF P PP G
Sbjct: 1232 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKG 1291
Query: 567 DRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGG 622
DRG G G G G + G PG + + G G G G +GG+G D G G + G
Sbjct: 1292 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1351
Query: 623 PGGPPGPLMEQMGGRRGGRGGPGKM 647
P GP GP + G G RG PG +
Sbjct: 1352 PVGPAGPAGKP--GPDGLRGLPGSV 1374
Score = 78.6 bits (192), Expect = 2e-14
Identities = 133/469 (28%), Positives = 168/469 (35%), Gaps = 101/469 (21%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQSSFRQD 276
G P S G+ G + G+ PT P G + Y G + S
Sbjct: 760 GVPGSRGED---GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL--G 814
Query: 277 HPSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA 332
P G G++ G SGP R +GP + RG + G G GG G G
Sbjct: 815 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK--GTSGGDGPHGP 872
Query: 333 GERGGFNKPGGPMD-EGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 391
G P GP GP GPP P +D L Q G
Sbjct: 873 PGERGLPGPQGPNGFPGPK---GPPGPPGKDG------------------LPGHPGQRGE 911
Query: 392 VKMNKRTGQPMIHIYLDK-----ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 446
V +TG P + ETG P G+ P + + GK+ G+K
Sbjct: 912 VGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKE--GTK-- 966
Query: 447 VSLARKKPPMNSMRGGLPPREG----RGMP-----PPLRGGPG-----GPGGPGGPMGRM 492
PP G P ++G RG P P GGPG GP GP GP G
Sbjct: 967 ---GDPGPP------GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 1017
Query: 493 GGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 550
G RG G G P G G +G P AG+ P G + T + +
Sbjct: 1018 GERGAAGSGGPIGPPGRPGPQGPPGA-------AGEKGVP----GEKGPIGPTGRDGVQG 1066
Query: 551 PKPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--- 602
P LP P PPG GD+G G G +G +G + G PG G G G
Sbjct: 1067 PVG---LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1123
Query: 603 --GFRGGRGMDRGGFGG-GRRG--GPGGPPGPL-MEQMGGRRGGRGGPG 645
G G RG +G FG G G G GPPGP+ ++ + G G +G G
Sbjct: 1124 ADGEPGARG-PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1171
Score = 73.9 bits (180), Expect = 4e-13
Identities = 118/440 (26%), Positives = 150/440 (34%), Gaps = 103/440 (23%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ-QSSSYGQQSSFRQDHPS 279
G G G + + G+ P P G Q + + + + G Q F
Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF------ 1137
Query: 280 SMGVYGQE-SGGFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGG 337
G G E + GF+GP + G P G D G M G G RG G G
Sbjct: 1138 --GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN---G 1192
Query: 338 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 397
+ P GP G +LGPP + E ++ + +QG + GV
Sbjct: 1193 ADGPQGP--PGGVGNLGPPGEKGEPGESGSPGIQG---------------EPGVKGPRGE 1235
Query: 398 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 457
G+ KG++ E P DG P N
Sbjct: 1236 RGE--------------KGESGQPGEPGPPGPKGPTGDDG----------------PKGN 1265
Query: 458 SMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSRG 512
G P G PP GGP G G G G G G G G P GP G RG
Sbjct: 1266 PGPVGFPGDPG----PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG 1321
Query: 513 NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGG 572
G+ + G +PG AP G + P G G+ G
Sbjct: 1322 PAGSPGSEGRQGGKGAKGDPGA-------------IGAPGKTGPVGP-----AGPAGKPG 1363
Query: 573 PGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG-----G 625
P G+RG G + +G PG + G G G G G RG D G G +G PG G
Sbjct: 1364 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRG-DAG--AKGEKGHPGLIGLIG 1420
Query: 626 PPGPLMEQMGGRRGGRGGPG 645
PPG EQ G +G RG PG
Sbjct: 1421 PPG---EQ--GEKGDRGLPG 1435
Score = 65.5 bits (158), Expect = 2e-10
Identities = 129/500 (25%), Positives = 162/500 (32%), Gaps = 84/500 (16%)
Query: 179 PQVPGSYPMQPVTAPPSYPPTS--YSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQS 236
PQ S +P P PT Y +P YD + Y P+ G++ + S
Sbjct: 248 PQQQPSRLHRPQNQEPQSQPTESLYYDYEPPYYDVMTTGTTPDYQDPTP-GEEEEILESS 306
Query: 237 SYG----QQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFS 292
+Q PP + Q+ YG+ + D P Y + G+
Sbjct: 307 LLPPLEEEQTDLQVPPTADRF---------QAEEYGEGGT---DPPEGPYDY---TYGYG 351
Query: 293 GPGENRSMSGPDNRGRGRGGFDRGGMSRGGRG-GGRGGMGAGERGGFNKPGGPMDEGPDL 351
+ GP G + G RG G G A G G P EGP
Sbjct: 352 DDYREETELGPALSAETAHS---GAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAG 408
Query: 352 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET 411
+GPP +QG V + G+ + G P + L
Sbjct: 409 LIGPPG------------IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 456
Query: 412 GKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGM 471
G GD K V Q + LA + PP G P G+
Sbjct: 457 GSGGGD-----------KGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPG 505
Query: 472 PPPLRGGPG--GPGGPGGPMGRMG--GRGGDRG--------GFPP----RGPRGSRGNPS 515
P L+G G GP GP GP G G G+ G RG G P +G RG G P
Sbjct: 506 SPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPG 565
Query: 516 GGGNVQHRA--GDWQCPNPGCGNQNFAWRTECNQCKAPK---PEGFL----PPPFPPPGG 566
G HR G P P + E P P G L PP P P G
Sbjct: 566 LPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPG 625
Query: 567 DRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGP 626
RG GP G +G G + G PG G G G +G G GP G
Sbjct: 626 VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG--------PQGAIGPHGEKGPQGK 677
Query: 627 PGPLMEQMGGRRGGRGGPGK 646
PG + M G G G PGK
Sbjct: 678 PG--LPGMPGSDGPPGHPGK 695
Score = 56.6 bits (135), Expect = 7e-08
Identities = 108/442 (24%), Positives = 141/442 (31%), Gaps = 65/442 (14%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 279
G+P + G Q +G + G + P G PS ++ G P
Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1185
Query: 280 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-GERGGF 338
G PG ++ P +G G G G RG G GE G
Sbjct: 1186 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1245
Query: 339 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 389
+PG P +GP D GP P DP + G D
Sbjct: 1246 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDG-------- 1297
Query: 390 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 449
GQP TG+ + P + + GK +G +
Sbjct: 1298 -------EPGQPGS----PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1346
Query: 450 ARKKPPMNSMR-GGLPPREG-RGMPPPL--RGGPG-----GPGGPGGPMGRMGGRGGDRG 500
K P+ G P +G RG+P + +G PG GP GP GP G G RG
Sbjct: 1347 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD--- 1403
Query: 501 GFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 555
G +G +G+P G Q GD P P G+ P G
Sbjct: 1404 ----AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ-GSPGQKGEMGIPGASGPIGPG 1458
Query: 556 FLPPPFPPPGGDRGR------GGPGGMRGGRGGLMDRGGPGGMFR----GGRGGDRGGFR 605
PP P P G +G GGP G +G +G G PG + + R
Sbjct: 1459 G-PPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD 1517
Query: 606 GGRGM--DRGGFGGGRRGGPGG 625
G R M D GG G PGG
Sbjct: 1518 GSRLMQEDEAIPTGGAPGSPGG 1539
Score = 36.2 bits (82), Expect = 0.099
Identities = 56/199 (28%), Positives = 64/199 (32%), Gaps = 44/199 (22%)
Query: 478 GPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQ 537
G GG P GP G G D GP S G G
Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRG------------ 380
Query: 538 NFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGR 597
+ E + +P G L P P G G GP G++G G + D G G R G
Sbjct: 381 ---LKGEKGEPAVLEP-GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 436
Query: 598 GGDRGGFRGGRGMD-----RGGFGGGRRG-------------------GPGGPPGPLMEQ 633
G G G G R G GGG +G GPPGP+
Sbjct: 437 PGSDGA-PGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM--G 493
Query: 634 MGGRRGGRGGPGKMD-KGE 651
GR G G PG KGE
Sbjct: 494 YTGRPGPLGQPGSPGLKGE 512
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 87.0 bits (214), Expect = 5e-17
Identities = 140/534 (26%), Positives = 186/534 (34%), Gaps = 55/534 (10%)
Query: 136 QPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPS 195
Q T P + PT P+ ++GG P G+ PQ P +P PP
Sbjct: 893 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP-GERGPQGPQGPVGFPGPK--GPPG 949
Query: 196 YPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ 255
P P ++ + Q G P G G G +P G
Sbjct: 950 PPGKDGLPGHPGQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG---- 1003
Query: 256 APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES-GGFSG-PGENRSMSGPDNRGRGRGGF 313
P + G++ + + P G+ G++ G G PGE R + G +GG
Sbjct: 1004 -PPGEQGLPGAAGKEGA--KGDPGPQGISGKDGPAGLRGFPGE-RGLPGAQGAPGLKGG- 1058
Query: 314 DRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQG 372
G G G G G AG G PG P +GP G P E G
Sbjct: 1059 -EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1117
Query: 373 LNDSVTLDDLADFFKQCGVVKMNKRTGQP-MIHIYLDKETGKPKGDATVSYEDPPTAKAA 431
+ V L A G G+P DK P G + P
Sbjct: 1118 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ---GPVGAPG 1174
Query: 432 VEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPR----EGRGMPPPLRG-----GPGGP 482
+ DG+ G + + + +K + PP +G PP +G GP GP
Sbjct: 1175 IAGGDGEP--GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1232
Query: 483 GGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP----GCGNQN 538
GP GP G G G D P+GP GS G+ G G + G+ P P G G
Sbjct: 1233 PGPPGPRGPQGPNGAD----GPQGPPGSVGSVGGVGE-KGEPGEAGNPGPPGEAGVGGP- 1286
Query: 539 FAWRTECNQCKAPKPEGFLPPPFP--PPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 596
+ E + P G PP PPG D +G PG + G G G PG + G
Sbjct: 1287 ---KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQDG 1342
Query: 597 RGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGPGK 646
GGD+G G G G GP GPPG P GR+G +G G+
Sbjct: 1343 VGGDKG--EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1394
Score = 85.1 bits (209), Expect = 2e-16
Identities = 130/482 (26%), Positives = 162/482 (33%), Gaps = 119/482 (24%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----------APSQYSQQSSSYGQQ 270
G+P GQQ + G Q G Q P P + G + P + + G++
Sbjct: 697 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 756
Query: 271 SSFRQD-------HPSSMGVYGQ-----------ESGGFSGPGENRSMSGPDNRG----- 307
+ +P GV G E G PG M +RG
Sbjct: 757 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 816
Query: 308 --RGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPG---GPMDEGPDLDLGPPVDPDE 361
RG G G R G G G G AGE+G PG P +GP G P P
Sbjct: 817 GPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 875
Query: 362 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 421
+ + A V G + G TG P TGKP T
Sbjct: 876 NGEKGARGVAG---------------KPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSG 919
Query: 422 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNSMRGGLPPREGRGMPPPLRG--G 478
+ PP + QG + V K PP + GLP G+ +G G
Sbjct: 920 GDGPPGPPGE------RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973
Query: 479 PGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 536
P GPGG GP G G G G+RG P GP G +G P G + GD
Sbjct: 974 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK-EGAKGD---------- 1022
Query: 537 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 596
P P G G+ GP G+RG G +RG PG G
Sbjct: 1023 -------------------------PGPQGISGKDGPAGLRGFPG---ERGLPGAQGAPG 1054
Query: 597 RGGDRG-----------GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ-MGGRRGGRGGP 644
G G G RG G G G R GP GPPGP E+ G +G +G
Sbjct: 1055 LKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1113
Query: 645 GK 646
G+
Sbjct: 1114 GR 1115
Score = 82.4 bits (202), Expect = 1e-15
Identities = 155/566 (27%), Positives = 197/566 (34%), Gaps = 79/566 (13%)
Query: 127 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 186
+P P P PQ P PQ G P +P G
Sbjct: 698 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG---ADGPPGHPGKEGQSG 754
Query: 187 MQPVTAPPS------YP-PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYG 239
+ PP YP P + S ++ G P G G + G
Sbjct: 755 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 814
Query: 240 QQPPTSYPPQTGSYSQA-PSQYSQQSSSYGQQSSFR----QDHPSSMGVYGQESGGFSG- 293
Q P G +A P+ S G++ +P G G S GF G
Sbjct: 815 QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG--STGFPGF 872
Query: 294 PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA----GERGGFNKPGGPMDEGP 349
PG N G+ RG G G RG G G GG PG P + GP
Sbjct: 873 PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 932
Query: 350 DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK 409
GP P +G D L Q G +TG P +
Sbjct: 933 QGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 983
Query: 410 E--TGK--PKGDATVSYEDPPTAKAAVEWFDGKD-FQGSKLKVSLARKKPPMNSMRG--- 461
+ TG+ P G+ P + + GK+ +G ++ K P +RG
Sbjct: 984 QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRGFPG 1042
Query: 462 --GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRG--GFPPR-GPRGSRGNP 514
GLP +G P L+GG G P GP GP+G G RG G G G P R GP+G G P
Sbjct: 1043 ERGLPGAQGA---PGLKGGEG-PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG-P 1097
Query: 515 SGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPG 574
+G G Q P G Q P P G P P GD+G G
Sbjct: 1098 AGEKGAPGEKGP-QGPAGRDGVQG--------PVGLPGPAG--PAGSPGEDGDKGEIGEP 1146
Query: 575 GMRGGRGGLMDRG--GPGGM-----FRGGRGGD-RGGFRGGRGMDRGGFGGGRRGGPGGP 626
G +G +G + G GP G+ G GGD G RG +GM G RG P GP
Sbjct: 1147 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP-GP 1205
Query: 627 PGPLMEQMGGRRGGRGGPGKMDKGEH 652
PGP+ G +G G PG +KGE+
Sbjct: 1206 PGPI-----GLQGLPGPPG--EKGEN 1224
Score = 77.8 bits (190), Expect = 3e-14
Identities = 77/211 (36%), Positives = 94/211 (44%), Gaps = 39/211 (18%)
Query: 462 GLPPREG-RGMPPPLRGGPGGPGGPG--------GPMGRMGGRG-----GDRGGFPPRGP 507
GLP G RG+ P RG PG PG PG GP G MG +G G +G P+G
Sbjct: 655 GLPGEAGPRGLLGP-RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 713
Query: 508 RGSRG--NPSGGGNVQHRAG-------DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLP 558
G +G P G Q + G D +PG Q+ E P P+G P
Sbjct: 714 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS----GEKGALGPPGPQG--P 767
Query: 559 PPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG--GDRG--GFRGGRGMDRGG 614
+P P G +G G G++G +G + G PG F+G G GDRG G G RG D G
Sbjct: 768 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGED-GP 824
Query: 615 FGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 645
G R GP G PGP G +G G PG
Sbjct: 825 EGPKGRAGPTGDPGP--SGQAGEKGKLGVPG 853
Score = 76.6 bits (187), Expect = 7e-14
Identities = 117/405 (28%), Positives = 147/405 (36%), Gaps = 87/405 (21%)
Query: 278 PSSMGVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSRGGRGGGRGGMG- 331
P S G G+ G GP R + GP RGR G D GG G G +G G
Sbjct: 558 PGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGAD-GGRGMPGEPGAKGDRGF 614
Query: 332 ------------AGERGGFNKPGGPMDE---GPDLDLGPPVDPDEDSDNSAIYVQGLNDS 376
GERG PG P D+ G D ++GP P E + +G +
Sbjct: 615 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 674
Query: 377 VTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFD 436
GQP + +D G PKG+ E P +
Sbjct: 675 ---------------------PGQPGM-AGVDGPPG-PKGNMGPQGEPGPPGQ------- 704
Query: 437 GKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG 496
QG+ L + P+ G P +G P L G PG G PG P G+
Sbjct: 705 ----QGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAGLPGADGPPGHP--GKEGQS 753
Query: 497 GDRGGFPPRGPRGSRGNP-----SGGGNVQHRAGD----WQCPNPGC-GNQNFAW-RTEC 545
G++G P GP+G G P G V+ G + PG G+ R E
Sbjct: 754 GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEV 813
Query: 546 NQCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 602
Q +G P P G G G GP G G +G L G PG R G G G
Sbjct: 814 GQIGPRGEDG----PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 869
Query: 603 -GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 646
GF G G ++G G + GP G GP + G RG RG GK
Sbjct: 870 PGFPGANG-EKGARGVAGKPGPRGQRGPTGPR--GSRGARGPTGK 911
Score = 72.8 bits (177), Expect = 1e-12
Identities = 131/464 (28%), Positives = 171/464 (36%), Gaps = 112/464 (24%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G+ + G++ G G Q P P G P+ + G+ P
Sbjct: 1099 GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG-----PAGSPGEDGDKGEIGE-----PGQ 1148
Query: 281 MGVYGQ--ESG-----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA- 332
G G E+G G GP ++G D RG +G + G G RG G
Sbjct: 1149 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPP 1206
Query: 333 GERGGFNKPGGPMDEGPDLDLGPPVDPDE------DSDNSAIYVQGLNDSVTLDDLADFF 386
G G PG P ++G + D+GP P N A QG SV
Sbjct: 1207 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--------- 1257
Query: 387 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 446
G V G+P E G P P +A V G+ +G K +
Sbjct: 1258 ---GSVGGVGEKGEP-------GEAGNPG----------PPGEAGVGGPKGE--RGEKGE 1295
Query: 447 VSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRG--- 500
P + G P +G +G P P+ G PG PG PG GP G+ G GGD+G
Sbjct: 1296 AGPPGAAGPPGAK--GPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQ-DGVGGDKGEDG 1351
Query: 501 --GFP----------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 548
G P P GP G RG P G + R G+ + +
Sbjct: 1352 DPGQPGPPGPSGEAGPPGPPGKRG-PPGAAGAEGRQGE---------------KGAKGEA 1395
Query: 549 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRG 606
A P G P P G G+ GP G+RG G + ++G PG + G G G G G
Sbjct: 1396 GAEGPPGKTGPVGPQ--GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1453
Query: 607 GRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 645
+G D G G +G PG GPPG EQ G +G RG PG
Sbjct: 1454 LKG-DPG--SKGEKGHPGLIGLIGPPG---EQ--GEKGDRGLPG 1489
Score = 70.5 bits (171), Expect = 5e-12
Identities = 84/264 (31%), Positives = 98/264 (37%), Gaps = 44/264 (16%)
Query: 422 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG 481
YED PT+ E+ G + + S+ + G P GM L GP G
Sbjct: 401 YEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGM---LVEGPPG 457
Query: 482 PGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGG---------NVQHRAGDWQCP 530
P GP G MG G +G G G RGP G G P G + R G
Sbjct: 458 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 517
Query: 531 NPGCGNQNFAWRTECNQCKA-----PKPEGFLPPPFPPPG-------GDRGRGGPGGMRG 578
P Q + Q + P P G P P G G+ G GP G RG
Sbjct: 518 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 577
Query: 579 GRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG-----GRRG--GPGGP 626
+G G PG R G G RG G +G RG D G G G RG GP GP
Sbjct: 578 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGP 635
Query: 627 PGPL----MEQMGGRRGGRGGPGK 646
PGP M G G RG PG+
Sbjct: 636 PGPPGDDGMRGEDGEIGPRGLPGE 659
Score = 63.2 bits (152), Expect = 8e-10
Identities = 106/408 (25%), Positives = 133/408 (32%), Gaps = 82/408 (20%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 279
G+P GQQ +GQ+ G + P G P ++ G P
Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1239
Query: 280 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG----AGER 335
G PG S+ G +G + G G GG +G G AG
Sbjct: 1240 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1299
Query: 336 GGFNKPGG---PMDEGPDLDLGP---PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 389
G PG P D+GP + GP P DP + G+ D
Sbjct: 1300 GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG-------- 1351
Query: 390 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 448
GQP G P PP + + QG K K
Sbjct: 1352 -------DPGQP----------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1394
Query: 449 LARKKPPMNSMR------GGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 495
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1395 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1454
Query: 496 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 546
GD G +G +G+P G Q GD P +PG
Sbjct: 1455 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1500
Query: 547 QCKAPKPEGFLPPPFPP----PGGDRGRGGPGGMRGGRGGLMDRGGPG 590
P P G L PP PP P G +G G G G +G D G PG
Sbjct: 1501 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG---DSGLPG 1543
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/188 (36%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 469 RGMPPP--LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRG---PRGSRGNPSGGGNVQHR 523
RG P P L G PG GGPG + G GD G PRG P G G P G
Sbjct: 540 RGPPGPMGLTGRPGPVGGPGSSGAK--GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 597
Query: 524 AGDWQCPNPGC-GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRG 581
G PG G++ F K + E G PP PP G GMRG G
Sbjct: 598 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP--------GDDGMRGEDG 649
Query: 582 GLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGR 637
+ RG PG G G RG G G GM G +G GP G PGP +Q G
Sbjct: 650 EIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ--GN 707
Query: 638 RGGRGGPG 645
G +G PG
Sbjct: 708 PGPQGLPG 715
Score = 44.7 bits (104), Expect = 3e-04
Identities = 87/379 (22%), Positives = 125/379 (32%), Gaps = 70/379 (18%)
Query: 178 YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 237
+P PG +Q + PP ++ G P G + G +
Sbjct: 1202 FPGPPGPIGLQGLPGPPG--------------EKGENGDVGPMGPPGPPGPRGPQGPNGA 1247
Query: 238 YGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG--GFSGPG 295
G Q P G + ++ + G P E+G G +GP
Sbjct: 1248 DGPQGPPGSVGSVGGVGEKGEP--GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1305
Query: 296 ENRSMSGPDNRGRGRG--GFDRGGMSRGGRG-GGRGGMGAGERGGFNKPGGPMDEGPDLD 352
+ G D G GF G G G+ G+G G++G PG P GP +
Sbjct: 1306 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG-GDKGEDGDPGQPGPPGPSGE 1364
Query: 353 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETG 412
GPP P + A +G + G +TG + G
Sbjct: 1365 AGPPGPPGKRGPPGAAGAEGRQGEKGAKG------EAGAEGPPGKTGP----VGPQGPAG 1414
Query: 413 KP--------------KGDATVSYEDPPTAKAAVEWFDG-KDFQGSKLKVSLARKKPPMN 457
KP +G + +D P G K GSK + + P +
Sbjct: 1415 KPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE----KGHPGLI 1470
Query: 458 SMRGGLPPRE-----GRGMP-----PPLRG-----GPGGPGGPGGPMGRMGGRG--GDRG 500
+ G PP E RG+P P +G GP GP GP GP G G +G G++G
Sbjct: 1471 GLIG--PPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1528
Query: 501 GFPPRGPRGSRGNPSGGGN 519
P G +G G P G+
Sbjct: 1529 STGPAGQKGDSGLPGPPGS 1547
Score = 34.3 bits (77), Expect = 0.38
Identities = 77/329 (23%), Positives = 97/329 (29%), Gaps = 35/329 (10%)
Query: 194 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 253
P PP S S ++ + G P G G++ G+ P G+
Sbjct: 1250 PQGPPGSVGSVGGVG-EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1308
Query: 254 S----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRG 309
P G + P+ G + G PG+ G
Sbjct: 1309 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1368
Query: 310 RGGFDRGGMSRGGRGGGRGGMGA-GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAI 368
RG G G +G GA GE G PG GP G P +
Sbjct: 1369 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1428
Query: 369 YVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTA 428
QGL + D G+ + G E G P + PP
Sbjct: 1429 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK-------GEKGHP---GLIGLIGPPGE 1478
Query: 429 KAAVEWFDGKDFQGSKLKVSL-ARKKPPMNSMRGGLP-PREGRGMP-PPLRGGPGGPGGP 485
QG K L + P GG+P P G P PP GP GP G
Sbjct: 1479 ------------QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1526
Query: 486 GGPMGRMGGRGGDRGGFPPRGPRGSRGNP 514
G G G +G G P GP GS G P
Sbjct: 1527 KGSTGPAGQKGD--SGLP--GPPGSPGPP 1551
Score = 29.6 bits (65), Expect = 9.3
Identities = 52/260 (20%), Positives = 81/260 (31%), Gaps = 37/260 (14%)
Query: 157 PQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYP----PTSYSSTQPTSYDQS 212
P G Q +G + P PG PP P P + + ++
Sbjct: 1331 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1390
Query: 213 SYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQ-- 270
+ + G P G G G + P G Q + Q G
Sbjct: 1391 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE--QGLPGAAGQDGPPGPMGP 1448
Query: 271 -----------SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR--GRGRGGFDRGG 317
S + HP +G+ G G G +R + G +G GG
Sbjct: 1449 PGLPGLKGDPGSKGEKGHPGLIGLIGPP--GEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1506
Query: 318 MSRGGRG-----------GGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 365
G G G +G G AG++G PG P GP ++ P+ P S
Sbjct: 1507 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL-PILSSKK 1565
Query: 366 SAIYVQGLNDSVTLDDLADF 385
+ + +G+ D++ D+
Sbjct: 1566 TRRHTEGMQADAD-DNILDY 1584
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 87.0 bits (214), Expect = 5e-17
Identities = 140/534 (26%), Positives = 186/534 (34%), Gaps = 55/534 (10%)
Query: 136 QPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPS 195
Q T P + PT P+ ++GG P G+ PQ P +P PP
Sbjct: 842 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP-GERGPQGPQGPVGFPGPK--GPPG 898
Query: 196 YPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ 255
P P ++ + Q G P G G G +P G
Sbjct: 899 PPGKDGLPGHPGQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG---- 952
Query: 256 APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES-GGFSG-PGENRSMSGPDNRGRGRGGF 313
P + G++ + + P G+ G++ G G PGE R + G +GG
Sbjct: 953 -PPGEQGLPGAAGKEGA--KGDPGPQGISGKDGPAGLRGFPGE-RGLPGAQGAPGLKGG- 1007
Query: 314 DRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQG 372
G G G G G AG G PG P +GP G P E G
Sbjct: 1008 -EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1066
Query: 373 LNDSVTLDDLADFFKQCGVVKMNKRTGQP-MIHIYLDKETGKPKGDATVSYEDPPTAKAA 431
+ V L A G G+P DK P G + P
Sbjct: 1067 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ---GPVGAPG 1123
Query: 432 VEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPR----EGRGMPPPLRG-----GPGGP 482
+ DG+ G + + + +K + PP +G PP +G GP GP
Sbjct: 1124 IAGGDGEP--GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1181
Query: 483 GGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP----GCGNQN 538
GP GP G G G D P+GP GS G+ G G + G+ P P G G
Sbjct: 1182 PGPPGPRGPQGPNGAD----GPQGPPGSVGSVGGVGE-KGEPGEAGNPGPPGEAGVGGP- 1235
Query: 539 FAWRTECNQCKAPKPEGFLPPPFP--PPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 596
+ E + P G PP PPG D +G PG + G G G PG + G
Sbjct: 1236 ---KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQDG 1291
Query: 597 RGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGPGK 646
GGD+G G G G GP GPPG P GR+G +G G+
Sbjct: 1292 VGGDKG--EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343
Score = 85.1 bits (209), Expect = 2e-16
Identities = 130/482 (26%), Positives = 162/482 (33%), Gaps = 119/482 (24%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----------APSQYSQQSSSYGQQ 270
G+P GQQ + G Q G Q P P + G + P + + G++
Sbjct: 646 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 705
Query: 271 SSFRQD-------HPSSMGVYGQ-----------ESGGFSGPGENRSMSGPDNRG----- 307
+ +P GV G E G PG M +RG
Sbjct: 706 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 765
Query: 308 --RGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPG---GPMDEGPDLDLGPPVDPDE 361
RG G G R G G G G AGE+G PG P +GP G P P
Sbjct: 766 GPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 824
Query: 362 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 421
+ + A V G + G TG P TGKP T
Sbjct: 825 NGEKGARGVAG---------------KPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSG 868
Query: 422 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNSMRGGLPPREGRGMPPPLRG--G 478
+ PP + QG + V K PP + GLP G+ +G G
Sbjct: 869 GDGPPGPPGE------RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922
Query: 479 PGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 536
P GPGG GP G G G G+RG P GP G +G P G + GD
Sbjct: 923 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK-EGAKGD---------- 971
Query: 537 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 596
P P G G+ GP G+RG G +RG PG G
Sbjct: 972 -------------------------PGPQGISGKDGPAGLRGFPG---ERGLPGAQGAPG 1003
Query: 597 RGGDRG-----------GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ-MGGRRGGRGGP 644
G G G RG G G G R GP GPPGP E+ G +G +G
Sbjct: 1004 LKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1062
Query: 645 GK 646
G+
Sbjct: 1063 GR 1064
Score = 82.4 bits (202), Expect = 1e-15
Identities = 155/566 (27%), Positives = 197/566 (34%), Gaps = 79/566 (13%)
Query: 127 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 186
+P P P PQ P PQ G P +P G
Sbjct: 647 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG---ADGPPGHPGKEGQSG 703
Query: 187 MQPVTAPPS------YP-PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYG 239
+ PP YP P + S ++ G P G G + G
Sbjct: 704 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 763
Query: 240 QQPPTSYPPQTGSYSQA-PSQYSQQSSSYGQQSSFR----QDHPSSMGVYGQESGGFSG- 293
Q P G +A P+ S G++ +P G G S GF G
Sbjct: 764 QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG--STGFPGF 821
Query: 294 PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA----GERGGFNKPGGPMDEGP 349
PG N G+ RG G G RG G G GG PG P + GP
Sbjct: 822 PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 881
Query: 350 DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK 409
GP P +G D L Q G +TG P +
Sbjct: 882 QGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 932
Query: 410 E--TGK--PKGDATVSYEDPPTAKAAVEWFDGKD-FQGSKLKVSLARKKPPMNSMRG--- 461
+ TG+ P G+ P + + GK+ +G ++ K P +RG
Sbjct: 933 QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRGFPG 991
Query: 462 --GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRG--GFPPR-GPRGSRGNP 514
GLP +G P L+GG G P GP GP+G G RG G G G P R GP+G G P
Sbjct: 992 ERGLPGAQGA---PGLKGGEG-PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG-P 1046
Query: 515 SGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPG 574
+G G Q P G Q P P G P P GD+G G
Sbjct: 1047 AGEKGAPGEKGP-QGPAGRDGVQG--------PVGLPGPAG--PAGSPGEDGDKGEIGEP 1095
Query: 575 GMRGGRGGLMDRG--GPGGM-----FRGGRGGD-RGGFRGGRGMDRGGFGGGRRGGPGGP 626
G +G +G + G GP G+ G GGD G RG +GM G RG P GP
Sbjct: 1096 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP-GP 1154
Query: 627 PGPLMEQMGGRRGGRGGPGKMDKGEH 652
PGP+ G +G G PG +KGE+
Sbjct: 1155 PGPI-----GLQGLPGPPG--EKGEN 1173
Score = 77.8 bits (190), Expect = 3e-14
Identities = 77/211 (36%), Positives = 94/211 (44%), Gaps = 39/211 (18%)
Query: 462 GLPPREG-RGMPPPLRGGPGGPGGPG--------GPMGRMGGRG-----GDRGGFPPRGP 507
GLP G RG+ P RG PG PG PG GP G MG +G G +G P+G
Sbjct: 604 GLPGEAGPRGLLGP-RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 662
Query: 508 RGSRG--NPSGGGNVQHRAG-------DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLP 558
G +G P G Q + G D +PG Q+ E P P+G P
Sbjct: 663 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS----GEKGALGPPGPQG--P 716
Query: 559 PPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG--GDRG--GFRGGRGMDRGG 614
+P P G +G G G++G +G + G PG F+G G GDRG G G RG D G
Sbjct: 717 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGED-GP 773
Query: 615 FGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 645
G R GP G PGP G +G G PG
Sbjct: 774 EGPKGRAGPTGDPGP--SGQAGEKGKLGVPG 802
Score = 76.6 bits (187), Expect = 7e-14
Identities = 117/405 (28%), Positives = 147/405 (36%), Gaps = 87/405 (21%)
Query: 278 PSSMGVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSRGGRGGGRGGMG- 331
P S G G+ G GP R + GP RGR G D GG G G +G G
Sbjct: 507 PGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGAD-GGRGMPGEPGAKGDRGF 563
Query: 332 ------------AGERGGFNKPGGPMDE---GPDLDLGPPVDPDEDSDNSAIYVQGLNDS 376
GERG PG P D+ G D ++GP P E + +G +
Sbjct: 564 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 623
Query: 377 VTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFD 436
GQP + +D G PKG+ E P +
Sbjct: 624 ---------------------PGQPGM-AGVDGPPG-PKGNMGPQGEPGPPGQ------- 653
Query: 437 GKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG 496
QG+ L + P+ G P +G P L G PG G PG P G+
Sbjct: 654 ----QGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAGLPGADGPPGHP--GKEGQS 702
Query: 497 GDRGGFPPRGPRGSRGNP-----SGGGNVQHRAGD----WQCPNPGC-GNQNFAW-RTEC 545
G++G P GP+G G P G V+ G + PG G+ R E
Sbjct: 703 GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEV 762
Query: 546 NQCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 602
Q +G P P G G G GP G G +G L G PG R G G G
Sbjct: 763 GQIGPRGEDG----PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 818
Query: 603 -GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 646
GF G G ++G G + GP G GP + G RG RG GK
Sbjct: 819 PGFPGANG-EKGARGVAGKPGPRGQRGPTGPR--GSRGARGPTGK 860
Score = 72.8 bits (177), Expect = 1e-12
Identities = 131/464 (28%), Positives = 171/464 (36%), Gaps = 112/464 (24%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G+ + G++ G G Q P P G P+ + G+ P
Sbjct: 1048 GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG-----PAGSPGEDGDKGEIGE-----PGQ 1097
Query: 281 MGVYGQ--ESG-----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA- 332
G G E+G G GP ++G D RG +G + G G RG G
Sbjct: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPP 1155
Query: 333 GERGGFNKPGGPMDEGPDLDLGPPVDPDE------DSDNSAIYVQGLNDSVTLDDLADFF 386
G G PG P ++G + D+GP P N A QG SV
Sbjct: 1156 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--------- 1206
Query: 387 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 446
G V G+P E G P P +A V G+ +G K +
Sbjct: 1207 ---GSVGGVGEKGEP-------GEAGNPG----------PPGEAGVGGPKGE--RGEKGE 1244
Query: 447 VSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRG--- 500
P + G P +G +G P P+ G PG PG PG GP G+ G GGD+G
Sbjct: 1245 AGPPGAAGPPGAK--GPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQ-DGVGGDKGEDG 1300
Query: 501 --GFP----------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 548
G P P GP G RG P G + R G+ + +
Sbjct: 1301 DPGQPGPPGPSGEAGPPGPPGKRG-PPGAAGAEGRQGE---------------KGAKGEA 1344
Query: 549 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRG 606
A P G P P G G+ GP G+RG G + ++G PG + G G G G G
Sbjct: 1345 GAEGPPGKTGPVGPQ--GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1402
Query: 607 GRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 645
+G D G G +G PG GPPG EQ G +G RG PG
Sbjct: 1403 LKG-DPG--SKGEKGHPGLIGLIGPPG---EQ--GEKGDRGLPG 1438
Score = 70.5 bits (171), Expect = 5e-12
Identities = 84/264 (31%), Positives = 98/264 (37%), Gaps = 44/264 (16%)
Query: 422 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG 481
YED PT+ E+ G + + S+ + G P GM L GP G
Sbjct: 350 YEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGM---LVEGPPG 406
Query: 482 PGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGG---------NVQHRAGDWQCP 530
P GP G MG G +G G G RGP G G P G + R G
Sbjct: 407 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 466
Query: 531 NPGCGNQNFAWRTECNQCKA-----PKPEGFLPPPFPPPG-------GDRGRGGPGGMRG 578
P Q + Q + P P G P P G G+ G GP G RG
Sbjct: 467 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 526
Query: 579 GRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG-----GRRG--GPGGP 626
+G G PG R G G RG G +G RG D G G G RG GP GP
Sbjct: 527 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGP 584
Query: 627 PGPL----MEQMGGRRGGRGGPGK 646
PGP M G G RG PG+
Sbjct: 585 PGPPGDDGMRGEDGEIGPRGLPGE 608
Score = 63.2 bits (152), Expect = 8e-10
Identities = 106/408 (25%), Positives = 133/408 (32%), Gaps = 82/408 (20%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 279
G+P GQQ +GQ+ G + P G P ++ G P
Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1188
Query: 280 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG----AGER 335
G PG S+ G +G + G G GG +G G AG
Sbjct: 1189 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1248
Query: 336 GGFNKPGG---PMDEGPDLDLGP---PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 389
G PG P D+GP + GP P DP + G+ D
Sbjct: 1249 GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG-------- 1300
Query: 390 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 448
GQP G P PP + + QG K K
Sbjct: 1301 -------DPGQP----------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343
Query: 449 LARKKPPMNSMR------GGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 495
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1344 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1403
Query: 496 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 546
GD G +G +G+P G Q GD P +PG
Sbjct: 1404 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1449
Query: 547 QCKAPKPEGFLPPPFPP----PGGDRGRGGPGGMRGGRGGLMDRGGPG 590
P P G L PP PP P G +G G G G +G D G PG
Sbjct: 1450 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG---DSGLPG 1492
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/188 (36%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 469 RGMPPP--LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRG---PRGSRGNPSGGGNVQHR 523
RG P P L G PG GGPG + G GD G PRG P G G P G
Sbjct: 489 RGPPGPMGLTGRPGPVGGPGSSGAK--GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 546
Query: 524 AGDWQCPNPGC-GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRG 581
G PG G++ F K + E G PP PP G GMRG G
Sbjct: 547 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP--------GDDGMRGEDG 598
Query: 582 GLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGR 637
+ RG PG G G RG G G GM G +G GP G PGP +Q G
Sbjct: 599 EIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ--GN 656
Query: 638 RGGRGGPG 645
G +G PG
Sbjct: 657 PGPQGLPG 664
Score = 44.7 bits (104), Expect = 3e-04
Identities = 87/379 (22%), Positives = 125/379 (32%), Gaps = 70/379 (18%)
Query: 178 YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 237
+P PG +Q + PP ++ G P G + G +
Sbjct: 1151 FPGPPGPIGLQGLPGPPG--------------EKGENGDVGPMGPPGPPGPRGPQGPNGA 1196
Query: 238 YGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG--GFSGPG 295
G Q P G + ++ + G P E+G G +GP
Sbjct: 1197 DGPQGPPGSVGSVGGVGEKGEP--GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1254
Query: 296 ENRSMSGPDNRGRGRG--GFDRGGMSRGGRG-GGRGGMGAGERGGFNKPGGPMDEGPDLD 352
+ G D G GF G G G+ G+G G++G PG P GP +
Sbjct: 1255 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG-GDKGEDGDPGQPGPPGPSGE 1313
Query: 353 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETG 412
GPP P + A +G + G +TG + G
Sbjct: 1314 AGPPGPPGKRGPPGAAGAEGRQGEKGAKG------EAGAEGPPGKTGP----VGPQGPAG 1363
Query: 413 KP--------------KGDATVSYEDPPTAKAAVEWFDG-KDFQGSKLKVSLARKKPPMN 457
KP +G + +D P G K GSK + + P +
Sbjct: 1364 KPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE----KGHPGLI 1419
Query: 458 SMRGGLPPRE-----GRGMP-----PPLRG-----GPGGPGGPGGPMGRMGGRG--GDRG 500
+ G PP E RG+P P +G GP GP GP GP G G +G G++G
Sbjct: 1420 GLIG--PPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1477
Query: 501 GFPPRGPRGSRGNPSGGGN 519
P G +G G P G+
Sbjct: 1478 STGPAGQKGDSGLPGPPGS 1496
Score = 34.3 bits (77), Expect = 0.38
Identities = 77/329 (23%), Positives = 97/329 (29%), Gaps = 35/329 (10%)
Query: 194 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 253
P PP S S ++ + G P G G++ G+ P G+
Sbjct: 1199 PQGPPGSVGSVGGVG-EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1257
Query: 254 S----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRG 309
P G + P+ G + G PG+ G
Sbjct: 1258 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1317
Query: 310 RGGFDRGGMSRGGRGGGRGGMGA-GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAI 368
RG G G +G GA GE G PG GP G P +
Sbjct: 1318 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1377
Query: 369 YVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTA 428
QGL + D G+ + G E G P + PP
Sbjct: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK-------GEKGHP---GLIGLIGPPGE 1427
Query: 429 KAAVEWFDGKDFQGSKLKVSL-ARKKPPMNSMRGGLP-PREGRGMP-PPLRGGPGGPGGP 485
QG K L + P GG+P P G P PP GP GP G
Sbjct: 1428 ------------QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1475
Query: 486 GGPMGRMGGRGGDRGGFPPRGPRGSRGNP 514
G G G +G G P GP GS G P
Sbjct: 1476 KGSTGPAGQKGD--SGLP--GPPGSPGPP 1500
Score = 29.6 bits (65), Expect = 9.3
Identities = 52/260 (20%), Positives = 81/260 (31%), Gaps = 37/260 (14%)
Query: 157 PQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYP----PTSYSSTQPTSYDQS 212
P G Q +G + P PG PP P P + + ++
Sbjct: 1280 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1339
Query: 213 SYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQ-- 270
+ + G P G G G + P G Q + Q G
Sbjct: 1340 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE--QGLPGAAGQDGPPGPMGP 1397
Query: 271 -----------SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR--GRGRGGFDRGG 317
S + HP +G+ G G G +R + G +G GG
Sbjct: 1398 PGLPGLKGDPGSKGEKGHPGLIGLIGPP--GEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1455
Query: 318 MSRGGRG-----------GGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 365
G G G +G G AG++G PG P GP ++ P+ P S
Sbjct: 1456 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL-PILSSKK 1514
Query: 366 SAIYVQGLNDSVTLDDLADF 385
+ + +G+ D++ D+
Sbjct: 1515 TRRHTEGMQADAD-DNILDY 1533
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 87.0 bits (214), Expect = 5e-17
Identities = 140/534 (26%), Positives = 186/534 (34%), Gaps = 55/534 (10%)
Query: 136 QPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPS 195
Q T P + PT P+ ++GG P G+ PQ P +P PP
Sbjct: 881 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP-GERGPQGPQGPVGFPGPK--GPPG 937
Query: 196 YPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ 255
P P ++ + Q G P G G G +P G
Sbjct: 938 PPGKDGLPGHPGQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG---- 991
Query: 256 APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES-GGFSG-PGENRSMSGPDNRGRGRGGF 313
P + G++ + + P G+ G++ G G PGE R + G +GG
Sbjct: 992 -PPGEQGLPGAAGKEGA--KGDPGPQGISGKDGPAGLRGFPGE-RGLPGAQGAPGLKGG- 1046
Query: 314 DRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQG 372
G G G G G AG G PG P +GP G P E G
Sbjct: 1047 -EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1105
Query: 373 LNDSVTLDDLADFFKQCGVVKMNKRTGQP-MIHIYLDKETGKPKGDATVSYEDPPTAKAA 431
+ V L A G G+P DK P G + P
Sbjct: 1106 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ---GPVGAPG 1162
Query: 432 VEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPR----EGRGMPPPLRG-----GPGGP 482
+ DG+ G + + + +K + PP +G PP +G GP GP
Sbjct: 1163 IAGGDGEP--GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1220
Query: 483 GGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP----GCGNQN 538
GP GP G G G D P+GP GS G+ G G + G+ P P G G
Sbjct: 1221 PGPPGPRGPQGPNGAD----GPQGPPGSVGSVGGVGE-KGEPGEAGNPGPPGEAGVGGP- 1274
Query: 539 FAWRTECNQCKAPKPEGFLPPPFP--PPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 596
+ E + P G PP PPG D +G PG + G G G PG + G
Sbjct: 1275 ---KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQDG 1330
Query: 597 RGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGPGK 646
GGD+G G G G GP GPPG P GR+G +G G+
Sbjct: 1331 VGGDKG--EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382
Score = 85.1 bits (209), Expect = 2e-16
Identities = 130/482 (26%), Positives = 162/482 (33%), Gaps = 119/482 (24%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----------APSQYSQQSSSYGQQ 270
G+P GQQ + G Q G Q P P + G + P + + G++
Sbjct: 685 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 744
Query: 271 SSFRQD-------HPSSMGVYGQ-----------ESGGFSGPGENRSMSGPDNRG----- 307
+ +P GV G E G PG M +RG
Sbjct: 745 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 804
Query: 308 --RGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPG---GPMDEGPDLDLGPPVDPDE 361
RG G G R G G G G AGE+G PG P +GP G P P
Sbjct: 805 GPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 863
Query: 362 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 421
+ + A V G + G TG P TGKP T
Sbjct: 864 NGEKGARGVAG---------------KPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSG 907
Query: 422 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNSMRGGLPPREGRGMPPPLRG--G 478
+ PP + QG + V K PP + GLP G+ +G G
Sbjct: 908 GDGPPGPPGE------RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961
Query: 479 PGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 536
P GPGG GP G G G G+RG P GP G +G P G + GD
Sbjct: 962 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK-EGAKGD---------- 1010
Query: 537 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 596
P P G G+ GP G+RG G +RG PG G
Sbjct: 1011 -------------------------PGPQGISGKDGPAGLRGFPG---ERGLPGAQGAPG 1042
Query: 597 RGGDRG-----------GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ-MGGRRGGRGGP 644
G G G RG G G G R GP GPPGP E+ G +G +G
Sbjct: 1043 LKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1101
Query: 645 GK 646
G+
Sbjct: 1102 GR 1103
Score = 82.4 bits (202), Expect = 1e-15
Identities = 155/566 (27%), Positives = 197/566 (34%), Gaps = 79/566 (13%)
Query: 127 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 186
+P P P PQ P PQ G P +P G
Sbjct: 686 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG---ADGPPGHPGKEGQSG 742
Query: 187 MQPVTAPPS------YP-PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYG 239
+ PP YP P + S ++ G P G G + G
Sbjct: 743 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 802
Query: 240 QQPPTSYPPQTGSYSQA-PSQYSQQSSSYGQQSSFR----QDHPSSMGVYGQESGGFSG- 293
Q P G +A P+ S G++ +P G G S GF G
Sbjct: 803 QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG--STGFPGF 860
Query: 294 PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA----GERGGFNKPGGPMDEGP 349
PG N G+ RG G G RG G G GG PG P + GP
Sbjct: 861 PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 920
Query: 350 DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK 409
GP P +G D L Q G +TG P +
Sbjct: 921 QGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 971
Query: 410 E--TGK--PKGDATVSYEDPPTAKAAVEWFDGKD-FQGSKLKVSLARKKPPMNSMRG--- 461
+ TG+ P G+ P + + GK+ +G ++ K P +RG
Sbjct: 972 QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRGFPG 1030
Query: 462 --GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRG--GFPPR-GPRGSRGNP 514
GLP +G P L+GG G P GP GP+G G RG G G G P R GP+G G P
Sbjct: 1031 ERGLPGAQGA---PGLKGGEG-PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG-P 1085
Query: 515 SGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPG 574
+G G Q P G Q P P G P P GD+G G
Sbjct: 1086 AGEKGAPGEKGP-QGPAGRDGVQG--------PVGLPGPAG--PAGSPGEDGDKGEIGEP 1134
Query: 575 GMRGGRGGLMDRG--GPGGM-----FRGGRGGD-RGGFRGGRGMDRGGFGGGRRGGPGGP 626
G +G +G + G GP G+ G GGD G RG +GM G RG P GP
Sbjct: 1135 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP-GP 1193
Query: 627 PGPLMEQMGGRRGGRGGPGKMDKGEH 652
PGP+ G +G G PG +KGE+
Sbjct: 1194 PGPI-----GLQGLPGPPG--EKGEN 1212
Score = 77.8 bits (190), Expect = 3e-14
Identities = 77/211 (36%), Positives = 94/211 (44%), Gaps = 39/211 (18%)
Query: 462 GLPPREG-RGMPPPLRGGPGGPGGPG--------GPMGRMGGRG-----GDRGGFPPRGP 507
GLP G RG+ P RG PG PG PG GP G MG +G G +G P+G
Sbjct: 643 GLPGEAGPRGLLGP-RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 701
Query: 508 RGSRG--NPSGGGNVQHRAG-------DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLP 558
G +G P G Q + G D +PG Q+ E P P+G P
Sbjct: 702 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS----GEKGALGPPGPQG--P 755
Query: 559 PPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG--GDRG--GFRGGRGMDRGG 614
+P P G +G G G++G +G + G PG F+G G GDRG G G RG D G
Sbjct: 756 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGED-GP 812
Query: 615 FGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 645
G R GP G PGP G +G G PG
Sbjct: 813 EGPKGRAGPTGDPGP--SGQAGEKGKLGVPG 841
Score = 76.6 bits (187), Expect = 7e-14
Identities = 117/405 (28%), Positives = 147/405 (36%), Gaps = 87/405 (21%)
Query: 278 PSSMGVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSRGGRGGGRGGMG- 331
P S G G+ G GP R + GP RGR G D GG G G +G G
Sbjct: 546 PGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGAD-GGRGMPGEPGAKGDRGF 602
Query: 332 ------------AGERGGFNKPGGPMDE---GPDLDLGPPVDPDEDSDNSAIYVQGLNDS 376
GERG PG P D+ G D ++GP P E + +G +
Sbjct: 603 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 662
Query: 377 VTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFD 436
GQP + +D G PKG+ E P +
Sbjct: 663 ---------------------PGQPGM-AGVDGPPG-PKGNMGPQGEPGPPGQ------- 692
Query: 437 GKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG 496
QG+ L + P+ G P +G P L G PG G PG P G+
Sbjct: 693 ----QGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAGLPGADGPPGHP--GKEGQS 741
Query: 497 GDRGGFPPRGPRGSRGNP-----SGGGNVQHRAGD----WQCPNPGC-GNQNFAW-RTEC 545
G++G P GP+G G P G V+ G + PG G+ R E
Sbjct: 742 GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEV 801
Query: 546 NQCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 602
Q +G P P G G G GP G G +G L G PG R G G G
Sbjct: 802 GQIGPRGEDG----PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 857
Query: 603 -GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 646
GF G G ++G G + GP G GP + G RG RG GK
Sbjct: 858 PGFPGANG-EKGARGVAGKPGPRGQRGPTGPR--GSRGARGPTGK 899
Score = 72.8 bits (177), Expect = 1e-12
Identities = 131/464 (28%), Positives = 171/464 (36%), Gaps = 112/464 (24%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G+ + G++ G G Q P P G P+ + G+ P
Sbjct: 1087 GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG-----PAGSPGEDGDKGEIGE-----PGQ 1136
Query: 281 MGVYGQ--ESG-----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA- 332
G G E+G G GP ++G D RG +G + G G RG G
Sbjct: 1137 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPP 1194
Query: 333 GERGGFNKPGGPMDEGPDLDLGPPVDPDE------DSDNSAIYVQGLNDSVTLDDLADFF 386
G G PG P ++G + D+GP P N A QG SV
Sbjct: 1195 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--------- 1245
Query: 387 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 446
G V G+P E G P P +A V G+ +G K +
Sbjct: 1246 ---GSVGGVGEKGEP-------GEAGNPG----------PPGEAGVGGPKGE--RGEKGE 1283
Query: 447 VSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRG--- 500
P + G P +G +G P P+ G PG PG PG GP G+ G GGD+G
Sbjct: 1284 AGPPGAAGPPGAK--GPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQ-DGVGGDKGEDG 1339
Query: 501 --GFP----------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 548
G P P GP G RG P G + R G+ + +
Sbjct: 1340 DPGQPGPPGPSGEAGPPGPPGKRG-PPGAAGAEGRQGE---------------KGAKGEA 1383
Query: 549 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRG 606
A P G P P G G+ GP G+RG G + ++G PG + G G G G G
Sbjct: 1384 GAEGPPGKTGPVGPQ--GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1441
Query: 607 GRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 645
+G D G G +G PG GPPG EQ G +G RG PG
Sbjct: 1442 LKG-DPG--SKGEKGHPGLIGLIGPPG---EQ--GEKGDRGLPG 1477
Score = 70.5 bits (171), Expect = 5e-12
Identities = 84/264 (31%), Positives = 98/264 (37%), Gaps = 44/264 (16%)
Query: 422 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG 481
YED PT+ E+ G + + S+ + G P GM L GP G
Sbjct: 389 YEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGM---LVEGPPG 445
Query: 482 PGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGG---------NVQHRAGDWQCP 530
P GP G MG G +G G G RGP G G P G + R G
Sbjct: 446 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505
Query: 531 NPGCGNQNFAWRTECNQCKA-----PKPEGFLPPPFPPPG-------GDRGRGGPGGMRG 578
P Q + Q + P P G P P G G+ G GP G RG
Sbjct: 506 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565
Query: 579 GRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG-----GRRG--GPGGP 626
+G G PG R G G RG G +G RG D G G G RG GP GP
Sbjct: 566 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGP 623
Query: 627 PGPL----MEQMGGRRGGRGGPGK 646
PGP M G G RG PG+
Sbjct: 624 PGPPGDDGMRGEDGEIGPRGLPGE 647
Score = 63.2 bits (152), Expect = 8e-10
Identities = 106/408 (25%), Positives = 133/408 (32%), Gaps = 82/408 (20%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 279
G+P GQQ +GQ+ G + P G P ++ G P
Sbjct: 1168 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1227
Query: 280 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG----AGER 335
G PG S+ G +G + G G GG +G G AG
Sbjct: 1228 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1287
Query: 336 GGFNKPGG---PMDEGPDLDLGP---PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 389
G PG P D+GP + GP P DP + G+ D
Sbjct: 1288 GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG-------- 1339
Query: 390 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 448
GQP G P PP + + QG K K
Sbjct: 1340 -------DPGQP----------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382
Query: 449 LARKKPPMNSMR------GGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 495
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1383 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1442
Query: 496 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 546
GD G +G +G+P G Q GD P +PG
Sbjct: 1443 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1488
Query: 547 QCKAPKPEGFLPPPFPP----PGGDRGRGGPGGMRGGRGGLMDRGGPG 590
P P G L PP PP P G +G G G G +G D G PG
Sbjct: 1489 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG---DSGLPG 1531
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/188 (36%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 469 RGMPPP--LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRG---PRGSRGNPSGGGNVQHR 523
RG P P L G PG GGPG + G GD G PRG P G G P G
Sbjct: 528 RGPPGPMGLTGRPGPVGGPGSSGAK--GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 585
Query: 524 AGDWQCPNPGC-GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRG 581
G PG G++ F K + E G PP PP G GMRG G
Sbjct: 586 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP--------GDDGMRGEDG 637
Query: 582 GLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGR 637
+ RG PG G G RG G G GM G +G GP G PGP +Q G
Sbjct: 638 EIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ--GN 695
Query: 638 RGGRGGPG 645
G +G PG
Sbjct: 696 PGPQGLPG 703
Score = 44.7 bits (104), Expect = 3e-04
Identities = 87/379 (22%), Positives = 125/379 (32%), Gaps = 70/379 (18%)
Query: 178 YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 237
+P PG +Q + PP ++ G P G + G +
Sbjct: 1190 FPGPPGPIGLQGLPGPPG--------------EKGENGDVGPMGPPGPPGPRGPQGPNGA 1235
Query: 238 YGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG--GFSGPG 295
G Q P G + ++ + G P E+G G +GP
Sbjct: 1236 DGPQGPPGSVGSVGGVGEKGEP--GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1293
Query: 296 ENRSMSGPDNRGRGRG--GFDRGGMSRGGRG-GGRGGMGAGERGGFNKPGGPMDEGPDLD 352
+ G D G GF G G G+ G+G G++G PG P GP +
Sbjct: 1294 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG-GDKGEDGDPGQPGPPGPSGE 1352
Query: 353 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETG 412
GPP P + A +G + G +TG + G
Sbjct: 1353 AGPPGPPGKRGPPGAAGAEGRQGEKGAKG------EAGAEGPPGKTGP----VGPQGPAG 1402
Query: 413 KP--------------KGDATVSYEDPPTAKAAVEWFDG-KDFQGSKLKVSLARKKPPMN 457
KP +G + +D P G K GSK + + P +
Sbjct: 1403 KPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE----KGHPGLI 1458
Query: 458 SMRGGLPPRE-----GRGMP-----PPLRG-----GPGGPGGPGGPMGRMGGRG--GDRG 500
+ G PP E RG+P P +G GP GP GP GP G G +G G++G
Sbjct: 1459 GLIG--PPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1516
Query: 501 GFPPRGPRGSRGNPSGGGN 519
P G +G G P G+
Sbjct: 1517 STGPAGQKGDSGLPGPPGS 1535
Score = 34.3 bits (77), Expect = 0.38
Identities = 77/329 (23%), Positives = 97/329 (29%), Gaps = 35/329 (10%)
Query: 194 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 253
P PP S S ++ + G P G G++ G+ P G+
Sbjct: 1238 PQGPPGSVGSVGGVG-EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1296
Query: 254 S----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRG 309
P G + P+ G + G PG+ G
Sbjct: 1297 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1356
Query: 310 RGGFDRGGMSRGGRGGGRGGMGA-GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAI 368
RG G G +G GA GE G PG GP G P +
Sbjct: 1357 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1416
Query: 369 YVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTA 428
QGL + D G+ + G E G P + PP
Sbjct: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK-------GEKGHP---GLIGLIGPPGE 1466
Query: 429 KAAVEWFDGKDFQGSKLKVSL-ARKKPPMNSMRGGLP-PREGRGMP-PPLRGGPGGPGGP 485
QG K L + P GG+P P G P PP GP GP G
Sbjct: 1467 ------------QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1514
Query: 486 GGPMGRMGGRGGDRGGFPPRGPRGSRGNP 514
G G G +G G P GP GS G P
Sbjct: 1515 KGSTGPAGQKGD--SGLP--GPPGSPGPP 1539
Score = 29.6 bits (65), Expect = 9.3
Identities = 52/260 (20%), Positives = 81/260 (31%), Gaps = 37/260 (14%)
Query: 157 PQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYP----PTSYSSTQPTSYDQS 212
P G Q +G + P PG PP P P + + ++
Sbjct: 1319 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1378
Query: 213 SYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQ-- 270
+ + G P G G G + P G Q + Q G
Sbjct: 1379 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE--QGLPGAAGQDGPPGPMGP 1436
Query: 271 -----------SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR--GRGRGGFDRGG 317
S + HP +G+ G G G +R + G +G GG
Sbjct: 1437 PGLPGLKGDPGSKGEKGHPGLIGLIGPP--GEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1494
Query: 318 MSRGGRG-----------GGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 365
G G G +G G AG++G PG P GP ++ P+ P S
Sbjct: 1495 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL-PILSSKK 1553
Query: 366 SAIYVQGLNDSVTLDDLADF 385
+ + +G+ D++ D+
Sbjct: 1554 TRRHTEGMQADAD-DNILDY 1572
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 86.3 bits (212), Expect = 8e-17
Identities = 132/477 (27%), Positives = 164/477 (34%), Gaps = 84/477 (17%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFR------ 274
G P G G Q G P YP G + ++ Q + F
Sbjct: 683 GHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDV 742
Query: 275 -----QDHPSSMGVYGQESG-GFSGPGENRSMSGPDNRGRGRGGFDRGGM-SRGGRGGGR 327
Q P + G G++ G G GP +G G+ GR G +
Sbjct: 743 GLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPK 802
Query: 328 GGMG-------AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 380
G +G GE+G K G P EG + GPP E A G V D
Sbjct: 803 GSIGFPGPLGPIGEKGKSGKTGQPGLEG---ERGPPGSRGERGQPGATGQPGPKGDVGQD 859
Query: 381 DLADFFKQCGVVKMNKRTG-----QPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVE 433
+ G+ + G P H D G P +G+ + P A V
Sbjct: 860 GAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVL 919
Query: 434 WFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGR-------GMPPPL--------RGG 478
GK + L PP GLP EGR G P PL RG
Sbjct: 920 GPQGKTGEVGPLG-ERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGF 978
Query: 479 PGGPGGPG--GPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 536
PG GGPG GP G G +G P GP G+ G+P G + G PG
Sbjct: 979 PGPKGGPGDPGPTGLKGDKG-------PPGPVGANGSPGERGPLGPAGG---IGLPG--- 1025
Query: 537 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 596
Q + P G P G+RG GP G G G L G PG G
Sbjct: 1026 ----------QSGSEGPVG--PAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSG 1073
Query: 597 RGGDRG-----GFRGGRGMDRGGFG-GGRRG--GPGGPPGPLMEQMGGRRGGRGGPG 645
GD+G G +G +G D+G G G+ G GP G PGP G +G RG PG
Sbjct: 1074 EEGDKGDVGAPGHKGSKG-DKGDAGPPGQPGIRGPAGHPGP--PGADGAQGRRGPPG 1127
Score = 81.6 bits (200), Expect = 2e-15
Identities = 139/539 (25%), Positives = 181/539 (33%), Gaps = 100/539 (18%)
Query: 153 ETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYP----PTSYSSTQPTS 208
E QP ++ G P GQ P +PG + + PP +P P +
Sbjct: 840 ERGQPGAT--GQPGPKGDVGQDGA--PGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRP 895
Query: 209 YDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY-----PPQTGSYSQAPSQYSQQ 263
+ GQ G G Q G+ P PP P ++
Sbjct: 896 GHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE 955
Query: 264 SSS--YGQQSSFRQDHPSSMGVYGQESGGFSGPGEN--RSMSGPD-----NRGRGRGG-- 312
+ G ++ P+ + + GG PG + GP N G G
Sbjct: 956 GAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPL 1015
Query: 313 FDRGGMSRGGRGGGRGGMG-AGERG--GFNKPGGPMDE----GPDLDLGPP--VDPD-ED 362
GG+ G+ G G +G AG++G G P GP + GP LGPP P E+
Sbjct: 1016 GPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEE 1075
Query: 363 SDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY 422
D + G S K +K P G+P +
Sbjct: 1076 GDKGDVGAPGHKGS----------------KGDKGDAGP---------PGQPGIRGPAGH 1110
Query: 423 EDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGP 482
PP A A QG + L +K + +RG + G PP L+G PG P
Sbjct: 1111 PGPPGADGA---------QGRRGPPGLFGQKGD-DGVRGFV----GVIGPPGLQGLPGPP 1156
Query: 483 GGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQN 538
G G G +G MG G G RG P+GP GS G P G V PG +
Sbjct: 1157 GEKGEVGDVGSMGPHGAPGPRG---PQGPTGSEGTPGLPGGVGQ---------PGAVGE- 1203
Query: 539 FAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG 598
+ E P P G P P P GD G G G G G +G PG G
Sbjct: 1204 ---KGERGDAGDPGPPG--APGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV 1258
Query: 599 GDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH 652
G G G G G+ G +G PG GP G G G PGK H
Sbjct: 1259 GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGH 1317
Score = 77.8 bits (190), Expect = 3e-14
Identities = 107/388 (27%), Positives = 137/388 (35%), Gaps = 109/388 (28%)
Query: 278 PSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG----AG 333
P G+ G+E G GP R + GP GR G M R G G RG G G
Sbjct: 496 PGHPGLKGEE--GAEGPQGPRGLQGPHGPP-GRVG----KMGRPGADGARGLPGDTGPKG 548
Query: 334 ERGGFNKPGGPMDEGPDLD---LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCG 390
+RG PG P ++G D +G P P ED + A G
Sbjct: 549 DRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTG--------------- 593
Query: 391 VVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLA 450
+ G+P P+G PT + V DG G+K V
Sbjct: 594 ------QAGEP-----------GPRGLLGPRGSPGPTGRPGVTGIDGAP--GAKGNVGPP 634
Query: 451 RKKPPM----NSMRGGLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMGGRGGDRGG 501
+ P N GLP +G P +G PG PG PG GP+G G G
Sbjct: 635 GEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEG----- 689
Query: 502 FPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPF 561
P G +G++G P G PP +
Sbjct: 690 --PTGEKGAQGPPGSAG---------------------------------------PPGY 708
Query: 562 PPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMD--RGGFGG 617
P P G +G G G++G +G + G PG G GD+G G G RG D G G
Sbjct: 709 PGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQ 768
Query: 618 GRRGGPGGPPGPLMEQMGGRRGGRGGPG 645
+ G GPPG E+ G+ G G PG
Sbjct: 769 AGQAGEEGPPGSAGEK--GKLGVPGLPG 794
Score = 68.9 bits (167), Expect = 1e-11
Identities = 120/471 (25%), Positives = 165/471 (35%), Gaps = 128/471 (27%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY----------SQAPSQYSQQSSSYGQQ 270
G+P GQQ ++G Q G Q P + G S P + G++
Sbjct: 635 GEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK 694
Query: 271 SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGM 330
+ Q P S G G+ GP + SG RG G ++G G G +G +
Sbjct: 695 GA--QGPPGSAG-----PPGYPGPRGVKGTSG----NRGLQG-EKGEKGEDGFPGFKGDV 742
Query: 331 GA-GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 389
G G++G PG ++GP+ G E+ + +G
Sbjct: 743 GLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKG----------------- 785
Query: 390 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 449
+ G P + Y G+P ++ + P G K K
Sbjct: 786 -------KLGVPGLPGY----PGRPGPKGSIGFPGPLGPI------------GEKGK--- 819
Query: 450 ARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG-----GPGGPMGRMGGRG--GDRG-- 500
S + G P EG PP RG G PG GP G +G+ G G G++G
Sbjct: 820 --------SGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLP 871
Query: 501 ------GFP-PRGPRGSRGNPSGGGNVQHRA-----GDWQCPNPG--CGNQNFAWRTECN 546
GFP P+GP G +G G+ R G P P G Q
Sbjct: 872 GLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVG-- 929
Query: 547 QCKAPKPEGFLPPPFPP-PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 605
P G PP PP P G++G G G G +G L G PG + + G G RG
Sbjct: 930 ------PLGERGPPGPPGPPGEQGLPGLEGREGAKGEL---GPPGPLGKEGPAGLRGF-- 978
Query: 606 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQER 656
G +GGPG P GP G +G +G PG + ER
Sbjct: 979 -----------PGPKGGPGDP-GPT-----GLKGDKGPPGPVGANGSPGER 1012
Score = 68.9 bits (167), Expect = 1e-11
Identities = 143/551 (25%), Positives = 178/551 (32%), Gaps = 123/551 (22%)
Query: 142 PTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVP-GSYPMQPVTAPPSYPPTS 200
P P N P GG P GQS P P G + PP PT
Sbjct: 999 PPGPVGANGSPGERGPLGPAGGIGLP----GQSGSEGPVGPAGKKGSRGERGPPG--PTG 1052
Query: 201 YSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQY 260
G+ G + G + S G + P Q G + P+ +
Sbjct: 1053 KDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGI--RGPAGH 1110
Query: 261 SQQSSSYGQQSSFRQDHPSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRG 316
+ G Q R+ P G G + G GP + + GP +G G D G
Sbjct: 1111 PGPPGADGAQG--RRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGE-KGEVG-DVG 1166
Query: 317 GMSRGGRGGGRGGMGA-------GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIY 369
M G G RG G G GG +PG ++G D G P P
Sbjct: 1167 SMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAP------- 1219
Query: 370 VQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAK 429
G+ G+ KGD+ S P K
Sbjct: 1220 --------------------GIPGPKGDIGE--------------KGDSGPSGAAGPPGK 1245
Query: 430 AAVEWFDGKDFQGSKLKVSLARKK-PPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG-- 486
DG +GS L PP + G+ G P GGPG PG G
Sbjct: 1246 KGPPGEDGA--KGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEP 1303
Query: 487 ---------GPMGRMG--GRGGDRG--------GFPPR-GPRGSRGNPSGGGNVQHRAGD 526
GP G MG GR G++G G P R GP G+RG P G R
Sbjct: 1304 GAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIP 1363
Query: 527 WQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFP-PPGGDRGRGGPGGMRGGRG--GL 583
PG AP G + PP P P G G G G +G +G GL
Sbjct: 1364 GPVGEPGL-------------LGAP---GQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGL 1407
Query: 584 MDRGGPGGMFRGGRGGDRG--GFRGGRGM-----DRGGFGGGRRGGPGGPPGPLMEQMGG 636
+ GP G G GD+G G +G G G G GP G GPL G
Sbjct: 1408 IGLIGPPG--EAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPL-----G 1460
Query: 637 RRGGRGGPGKM 647
++G +G PG M
Sbjct: 1461 QKGSKGSPGSM 1471
Score = 67.8 bits (164), Expect = 3e-11
Identities = 111/411 (27%), Positives = 145/411 (35%), Gaps = 65/411 (15%)
Query: 270 QSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRG-GRGGGRG 328
+ S D + +G ++ G++ +M GPD R + + G G G +G
Sbjct: 321 ERSLDPDSGTELGTLETKAAREDEEGDDSTM-GPDFRAAEYPSRTQFQIFPGAGEKGAKG 379
Query: 329 GMGAGERGGF--NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFF 386
E+G PG P +G GPP P D GL +D +
Sbjct: 380 EPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIR--- 436
Query: 387 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 446
G P I + P A S++ PP + F Q +
Sbjct: 437 ------------GPPGTVIMM------PFQFAGGSFKGPPVS------FQQAQAQAVLQQ 472
Query: 447 VSLARKKPPMNSMRGGLPPREGRGMPPPLRG--------GPGGPGGPGGPMGRMG--GRG 496
L+ K PP G P G P L+G GP G GP GP GR+G GR
Sbjct: 473 TQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRP 532
Query: 497 GDRG--GFP----PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTE-----C 545
G G G P P+G RG G P G R PG ++ E
Sbjct: 533 GADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPT 592
Query: 546 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--G 603
Q P P G L P P G GR G G+ G G + G PG G+ G+ G G
Sbjct: 593 GQAGEPGPRGLLGPRGSP--GPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQG 650
Query: 604 FRGGRGMDRGGFGGGRRGGPG-----GPPGPL----MEQMGGRRGGRGGPG 645
G +G+ G G PG G GPL E G +G +G PG
Sbjct: 651 LPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPG 701
Score = 64.7 bits (156), Expect = 3e-10
Identities = 73/224 (32%), Positives = 88/224 (39%), Gaps = 39/224 (17%)
Query: 454 PPMNSMRGGLPPREG-RGMPPPL-----RGGPGGPGGPG-----GPMGRMG-----GRGG 497
PP + G P +G RG+P RG G PG PG G G +G G G
Sbjct: 522 PPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDG 581
Query: 498 DRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFL 557
+RG P GP G G P G + R PG + AP +G +
Sbjct: 582 ERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGID----------GAPGAKGNV 631
Query: 558 PPPFP--PPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGR 608
PP PPG G +G GP G+ G G G PG G G G G G
Sbjct: 632 GPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPT 691
Query: 609 GMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG-KMDKGE 651
G ++G G GP G PGP + G G RG G K +KGE
Sbjct: 692 G-EKGAQGPPGSAGPPGYPGP--RGVKGTSGNRGLQGEKGEKGE 732
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 85.5 bits (210), Expect = 1e-16
Identities = 142/543 (26%), Positives = 191/543 (35%), Gaps = 57/543 (10%)
Query: 128 PAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPM 187
P P Q T P + T P+ ++GG + P+ G+ + PQ P +P
Sbjct: 903 PGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGG-DGPAGPPGERGPNGPQGPTGFPG 961
Query: 188 QPVTAPPSYPPTSYSSTQPTSYDQSSYS-QQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 246
PP P P ++ + + G P G Q G+ G++
Sbjct: 962 PK--GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGP 1019
Query: 247 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG-GFSGPGENRSMSGPDN 305
P G P ++ + + P G+ G++ G G +R + GP
Sbjct: 1020 PGPPGEQG-LPGLAGKEGT---------KGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVG 1069
Query: 306 RGRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSD 364
+G + G G G G G AG G PG P +GP G P E
Sbjct: 1070 ALGLKG--NEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGP 1127
Query: 365 NSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK-ETGKP--KGDATVS 421
GL V L A G V G DK E G+P KG
Sbjct: 1128 QGPAGRDGLQGPVGLPGPA------GPVGPPGEDG--------DKGEIGEPGQKGSKGDK 1173
Query: 422 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPP--LRGGP 479
E P + G+ R + + +G PR G P P L+G P
Sbjct: 1174 GEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLP 1233
Query: 480 GGPG--GPGGPMGRMG--------GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQC 529
G PG G G +G+MG G G G P+GP G GNP G +
Sbjct: 1234 GPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEP 1293
Query: 530 PNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFP--PPGGDRGRGGPGGMRGGRGGLMDRG 587
PG G + E + P G PP P PPG D +G PG + G G G
Sbjct: 1294 GLPGEGGPP-GPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV-GFPGDPGPPG 1351
Query: 588 GPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG--GPPGPLMEQMGGRRGGRGG 643
PG + G GD+G G G G G G PG GPPGP + GR+G +G
Sbjct: 1352 EPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPE--GRQGEKGA 1409
Query: 644 PGK 646
G+
Sbjct: 1410 KGE 1412
Score = 85.1 bits (209), Expect = 2e-16
Identities = 176/700 (25%), Positives = 228/700 (32%), Gaps = 156/700 (22%)
Query: 85 TPTAPQAYSQPV--------QGYGTGAYDTTTATVTTTQASYAAQSAYGT------QPAY 130
TPT +A P + G G YD + T + Y YG QP
Sbjct: 311 TPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYD-DLTYGEGEENPDQPTD 369
Query: 131 PAYGQQ-PAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQV-PGSYPMQ 188
P G + P +TA T P G + + ++ NY P P S P +
Sbjct: 370 PGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSE 429
Query: 189 PVTAPPSYPPTSYSST----------------QPTSYDQSSYSQQNTYGQPSSYGQQSSY 232
P+ T Y +P + + G P G
Sbjct: 430 IGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPT 489
Query: 233 GQQSSYGQQPPTSYPPQTGSY-----------------------SQAPSQYSQQSSSYG- 268
GQ G++ P P G+ S+ P +Q+S +
Sbjct: 490 GQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAI 549
Query: 269 -QQSSFRQDHPSS-MGVYGQE-------SGGFSG-PGE-----NRSMSGPDNRG-----R 308
QQ+ P+ MG+ G+ SGG G PG+ R + GP R
Sbjct: 550 LQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRR 609
Query: 309 GRGGFDRGGMSRGGRGGGRGGMGAGERGGF-NKPGGPMDEGPDLDLGPPVDPDEDSDNSA 367
GR G D G G+ G +G G G + G D GP GPP D E D+
Sbjct: 610 GRAGSD-GARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGE 668
Query: 368 IYVQGLNDSVTLDDLADFFKQCG------VVKMNKRTGQPMIHIYLDKETGKPKGDATVS 421
+ +GL L G V M+ + G P ++ E G P
Sbjct: 669 VGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPG-PKGNVGPQGEPGPPGQQGNPG 727
Query: 422 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGP 479
+ P + A+ K G KP + M G G P G+ PP +GG
Sbjct: 728 AQGLPGPQGAIGPPGEKGPLG----------KPGLPGMPGADGPPGHPGKEGPPGEKGGQ 777
Query: 480 GGPGGPGGPMGRMGGRG--------------------------------GDRGGFPPRGP 507
G PG P GP+G G RG GDRG P GP
Sbjct: 778 GPPG-PQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGP 836
Query: 508 RGSRG--NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE-GFLPPPFP-- 562
RG G P G G G P G + PK GF P FP
Sbjct: 837 RGEDGPEGPKGRGGPNGDPGPLGPPGEK-GKLGVPGLPGYPGRQGPKGSIGF--PGFPGA 893
Query: 563 --------PPG--GDRGRGGPGGMRGGRG--GLMDRGGPGGMFRGGRGGDRGGFRGGRGM 610
PG G RG+ GP G RG RG G+ + GP +G GGD G
Sbjct: 894 NGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGP----KGNSGGDGPAGPPGERG 949
Query: 611 DRGGFGGGRRGGPGGPPGPL-MEQMGGRRGGRGGPGKMDK 649
G G GP GPPGP + + G G RG G K
Sbjct: 950 PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 989
Score = 83.6 bits (205), Expect = 5e-16
Identities = 128/455 (28%), Positives = 158/455 (34%), Gaps = 81/455 (17%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G+ GQ+ S G + G PT PQ PS + GQQ F Q
Sbjct: 1159 GEIGEPGQKGSKGDKGEQGPPGPTG--PQGPIGQPGPSGADGEPGPRGQQGLFGQK---- 1212
Query: 281 MGVYGQESG-GFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGA------ 332
G E GF GP + G P G D G M G G RG GA
Sbjct: 1213 ----GDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGP 1268
Query: 333 -GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 391
G GG PG ++G + G P P E +G A G
Sbjct: 1269 QGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGP 1328
Query: 392 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 451
+ G P + + G P + PP K DG+ Q
Sbjct: 1329 PGDDGPKGSPG-PVGFPGDPGPPGEPGPAGQDGPPGDKGD----DGEPGQT--------- 1374
Query: 452 KKPPMNSMRGGLPPREGRGMP--PPLRGGPGGPGGPGGPMGRMGGRG-----GDRGGFPP 504
G P G P PP + GP GP GP G G G +G G G P
Sbjct: 1375 ----------GSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGP 1424
Query: 505 RGPRGSRGNPSGGG--NVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFP 562
GP+G+ G P G + G+ P +P P+G P P
Sbjct: 1425 IGPQGAPGKPGPDGLRGIPGPVGEQGLPG------------------SPGPDG-PPGPMG 1465
Query: 563 PPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGG 618
PPG G +G GP G + G GL+ GP G G GDRG G +G G +G G
Sbjct: 1466 PPGLPGLKGDSGPKGEK-GHPGLIGLIGPPG--EQGEKGDRGLPGPQGSSG-PKGEQGIT 1521
Query: 619 RRGGPGGPPGPL-MEQMGGRRGGRGGPGKM-DKGE 651
GP GPPGP + G +G +G G KGE
Sbjct: 1522 GPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGE 1556
Score = 80.5 bits (197), Expect = 5e-15
Identities = 122/402 (30%), Positives = 151/402 (37%), Gaps = 76/402 (18%)
Query: 278 PSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAG 333
P G G++ G G GP R +GP RG G RG + G G GG G
Sbjct: 888 PGFPGANGEKGGRGTPGKPGPRGQRGPTGP----RGERG-PRGITGKPGPKGNSGGDGPA 942
Query: 334 ERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVK 393
G P GP +GP GP P + G GVV
Sbjct: 943 GPPGERGPNGP--QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVG 1000
Query: 394 MNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK 453
TG ETG P G+ P + + GK+ G+K A
Sbjct: 1001 PQGPTG----------ETG-PMGERGHPGPPGPPGEQGLPGLAGKE--GTKGDPGPA--- 1044
Query: 454 PPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGN 513
GLP ++G PP LRG PG G PG P+G +G +G + PP GP GS G
Sbjct: 1045 --------GLPGKDG---PPGLRGFPGDRGLPG-PVGALGLKGNEGPPGPP-GPAGSPGE 1091
Query: 514 --PSGGGN---VQHRAGDWQCPNPGC--------GNQNFAWRTECN-QCKAPKPEGFLPP 559
P+G + R G P P G Q A R P P G
Sbjct: 1092 RGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAG---- 1147
Query: 560 PFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--------GFRGGRG 609
P PPG GD+G G G +G +G ++G PG G G G G RG +G
Sbjct: 1148 PVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQG 1207
Query: 610 MDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGE 651
+ G RG P GPPGP+ G +G G PG +KGE
Sbjct: 1208 LFGQKGDEGPRGFP-GPPGPV-----GLQGLPGPPG--EKGE 1241
Score = 69.7 bits (169), Expect = 8e-12
Identities = 119/468 (25%), Positives = 154/468 (32%), Gaps = 143/468 (30%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS----QAPSQYSQQSSSYGQQSSFRQD 276
G+P GQQ +GQ+ G + P +P G P ++ GQ
Sbjct: 1198 GEPGPRGQQGLFGQK---GDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPP 1254
Query: 277 HP----SSMGVYGQES--GGFSGPGENRSMSGPDNRGR----GRGG-----FDRGGMSRG 321
P + G G + GG PG P G G GG +RG
Sbjct: 1255 GPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGES 1314
Query: 322 GRGGGRGGMGA-------GERG-----GF-NKPGGPMDEGPDLDLGPPVDPDEDSDNSAI 368
G G G G G +G GF PG P + GP GPP D +D +
Sbjct: 1315 GPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG-- 1372
Query: 369 YVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTA 428
+TG P TG+P PP
Sbjct: 1373 ----------------------------QTGSP-------GPTGEPGPSGPPGKRGPP-G 1396
Query: 429 KAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPP--LRGGPG------ 480
A E G+ +G+K + L + PP + G + P+ G P P LRG PG
Sbjct: 1397 PAGPEGRQGE--KGAKGEAGL--EGPPGKT--GPIGPQGAPGKPGPDGLRGIPGPVGEQG 1450
Query: 481 -----GPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQ 528
GP GP GPMG G G GD G P+G +G+P G Q GD
Sbjct: 1451 LPGSPGPDGPPGPMGPPGLPGLKGDSG------PKGEKGHPGLIGLIGPPGEQGEKGDRG 1504
Query: 529 CPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP--PGGDRGRGGPGGMRGGRGGLMDR 586
P P PK E + P P P G G GP G +G +G
Sbjct: 1505 LPGP-------------QGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGS---- 1547
Query: 587 GGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQM 634
GP G +G G GP GPPG +++ +
Sbjct: 1548 SGPTG-------------------PKGEAGHPGPPGPPGPPGEVIQPL 1576
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 85.1 bits (209), Expect = 2e-16
Identities = 146/567 (25%), Positives = 182/567 (32%), Gaps = 84/567 (14%)
Query: 125 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGS 184
G Q A G Q P P +G KP + P G P L + +P GS
Sbjct: 654 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP----GEAGAPGLVGPRGERGFPGERGS 709
Query: 185 YPMQPVTAPPSYP-------PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 237
Q + P P P S Q Q G+ + G G +
Sbjct: 710 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769
Query: 238 YGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGE 296
G++ P P + G P + + G++ P+ +G PGE
Sbjct: 770 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG------SAGARGAPGE 823
Query: 297 NRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGP 355
R +GP G GF G G+ G +G G AG++G PG +GP GP
Sbjct: 824 -RGETGPP----GPAGF-AGPPGADGQPGAKGEQGEAGQKGDAGAPG---PQGPSGAPGP 874
Query: 356 PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK-- 413
A QG + A + G N G P K+ K
Sbjct: 875 QGPTGVTGPKGARGAQGPPGATGFPGAAG---RVGPPGSNGNPGPPGPPGPSGKDGPKGA 931
Query: 414 -----PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GL 463
P G A P + G D A P + G GL
Sbjct: 932 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG------AEGPPGPQGLAGQRGIVGL 985
Query: 464 PPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 523
P + G P L G G PG G P G GDRG P GP G G G
Sbjct: 986 PGQRGERGFPGLPGPSGEPGKQGAP-----GASGDRGPPGPVGPPGLTGPAGEPGREGSP 1040
Query: 524 AGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGG------DRGRGG----- 572
D G R E AP G PP P P G DRG G
Sbjct: 1041 GADGPPGRDGAAGVK-GDRGETGAVGAPGAPG--PPGSPGPAGPTGKQGDRGEAGAQGPM 1097
Query: 573 -PGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGM--------DRGGFGGG 618
P G G RG +G G G G+RG GF G +G+ D+G G
Sbjct: 1098 GPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPA 1157
Query: 619 RRGGPGGPPGPLMEQMGGRRGGRGGPG 645
GP GPPGP+ G+ G G PG
Sbjct: 1158 GPSGPRGPPGPV--GPSGKDGANGIPG 1182
Score = 81.3 bits (199), Expect = 3e-15
Identities = 110/375 (29%), Positives = 130/375 (34%), Gaps = 47/375 (12%)
Query: 294 PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-GERGGFNKPGGPMDEGPDLD 352
PG+ + + GP +G G RG RG +G GA G RG +PG P + GP
Sbjct: 109 PGDIKDIVGPKGPPGPQGPAGEQG-PRGDRGD-KGEKGAPGPRGRDGEPGTPGNPGPPGP 166
Query: 353 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ-----PMIHIYL 407
GPP P + +A G ++ L G + G P
Sbjct: 167 PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN 226
Query: 408 DKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----G 462
E G+P + PP G D + K + R P RG G
Sbjct: 227 PGEPGEPGVSGPMGPRGPPGPPGK----PGDDGEAGKPGKAGERGPPGPQGARGFPGTPG 282
Query: 463 LPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNV 520
LP +G P L G G G PG G G G G G PRG G RG G
Sbjct: 283 LPGVKGHRGYPGLDGAKGEAGAPG-VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 341
Query: 521 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP-FPPPGGDRGRGGPGGMRGG 579
R D Q P P P P G P FP G +G GP G RG
Sbjct: 342 GARGNDGQ-PGPA---------------GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385
Query: 580 RGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRG--GPGGPPGPLME 632
G RG PG G G G G G +G G G GP GPPGP
Sbjct: 386 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP-QG 444
Query: 633 QMG--GRRGGRGGPG 645
G G +G G PG
Sbjct: 445 ATGPLGPKGQTGEPG 459
Score = 80.5 bits (197), Expect = 5e-15
Identities = 140/559 (25%), Positives = 180/559 (32%), Gaps = 100/559 (17%)
Query: 131 PAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG---SYPM 187
P + P A P P P+ G P N +PG S
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 424
Query: 188 QPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYP 247
+ P +P + Q G GQ G G+Q P P
Sbjct: 425 PGIAGAPGFPGP-----------RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473
Query: 248 PQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG 307
G AP ++ G++ + + P +G G G G NR G D
Sbjct: 474 GPAGPQG-APGPAGEE----GKRGA--RGEPGGVGPIGPP--GERGAPGNRGFPGQDGLA 524
Query: 308 RGRGG-FDRGGMSRGGRGGGRGGMGA----GERGGFNKPGGPMDEGPDLDLGPPVDPDED 362
+G +RG G G G G G G G P D GP +GP P ED
Sbjct: 525 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 584
Query: 363 SDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY 422
QG GQP + + + G+ +
Sbjct: 585 GRPGPPGPQGAR------------------------GQPGVMGFPGPKGAN--GEPGKAG 618
Query: 423 EDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGP 482
E + GKD + PP + G +G P +G PG P
Sbjct: 619 EKGLPGAPGLRGLPGKDGE-------TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 671
Query: 483 GGPGGPMGRMGGRGGDRG-----GFPPR-GPRGSRGNPS--GGGNVQHRAGDWQCPN-PG 533
G PG GG+ GD+G G P GPRG RG P G Q G P PG
Sbjct: 672 GPPGE-----GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 726
Query: 534 CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMF 593
A P +G PP G+RG G G +G RG + ++G G
Sbjct: 727 TDGPKGA----SGPAGPPGAQG--PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780
Query: 594 R-GGRG--------GDRG--GFRGGRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGR 637
+ GGRG G G G +G G G RG PG GPPGP G
Sbjct: 781 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP--AGFAGP 838
Query: 638 RGGRGGPG-KMDKGEHRQE 655
G G PG K ++GE Q+
Sbjct: 839 PGADGQPGAKGEQGEAGQK 857
Score = 77.4 bits (189), Expect = 4e-14
Identities = 139/548 (25%), Positives = 177/548 (32%), Gaps = 127/548 (23%)
Query: 117 SYAAQSAYG--TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQS 174
++AAQ A G + G P P+ P PQ G +P G+
Sbjct: 178 NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEP----GEP 233
Query: 175 NYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQ 234
S P P P PP P + +P + G P G + G
Sbjct: 234 GVSGPMGPRGPP-----GPPGKPGDDGEAGKP--------GKAGERGPPGPQGARGFPGT 280
Query: 235 QSSYGQQPPTSYPPQTGSYSQAPSQ-YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSG 293
G + YP G+ +A + +S S G+ S P MG G
Sbjct: 281 PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS-----PGPMGPRGL------- 328
Query: 294 PGENRSMSGPDNRGRGRGGFDRGGMSRG----GRGGGRGGMGA----GERGGFNKPGGPM 345
PGE R +GP RG + G + G GG G GA GE G G
Sbjct: 329 PGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 387
Query: 346 DEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI 405
+GP + G P P G + + D + G + G P
Sbjct: 388 AQGPRGEPGTPGSPGP---------AGASGNPGTDGIPGAKGSAGAPGIAGAPGFP---- 434
Query: 406 YLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPP 465
P+G PP + A K G +P + +G P
Sbjct: 435 -------GPRG--------PPGPQGATGPLGPKGQTG----------EPGIAGFKGEQGP 469
Query: 466 REGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHR 523
+ G P GP GP G GP G G RG G+ GG P GP G RG P
Sbjct: 470 K---GEP-----GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAP--------- 512
Query: 524 AGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPGGMRGGRGG 582
GN+ F P +G P P G G GP G G G
Sbjct: 513 -----------GNRGF-----------PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 550
Query: 583 LMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRR 638
+ G PG GR GD G G+ G G R GP GP G P + G +
Sbjct: 551 PGEPGLPGARGLTGRPGDAG--PQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK 608
Query: 639 GGRGGPGK 646
G G PGK
Sbjct: 609 GANGEPGK 616
Score = 77.0 bits (188), Expect = 5e-14
Identities = 118/424 (27%), Positives = 149/424 (35%), Gaps = 65/424 (15%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSS-FRQDHPS 279
GQP + G+Q GQ+ G P P Q P+ + + G Q P
Sbjct: 843 GQPGAKGEQGEAGQKGDAGAPGPQG--PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 900
Query: 280 SMGVYGQE-SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-GERGG 337
+ G G S G GP SG D RG D G R G G +G G GE+G
Sbjct: 901 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG--DSGPPGRAGEPGLQGPAGPPGEKG- 957
Query: 338 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 397
+PG D+GP GPP QGL + L + G +
Sbjct: 958 --EPG---DDGPSGAEGPPGP------------QGLAGQRGIVGLPGQRGERGFPGLPGP 1000
Query: 398 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 457
+G+P GK +G S + P G + + + S PP
Sbjct: 1001 SGEP----------GK-QGAPGASGDRGPPGPVGPPGLTGPAGEPGR-EGSPGADGPPGR 1048
Query: 458 SMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRG- 512
G+ G G PG PG PG GP G+ G RG G +G P GP G+RG
Sbjct: 1049 DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1108
Query: 513 -NPSGGGNVQHRAGDWQCPNPG----CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG-- 565
P G + AG+ PG G++ F P + P P G
Sbjct: 1109 QGPQGPRGDKGEAGE-----PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1163
Query: 566 GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGG 625
G G GP G G G G PG GR G+ G G G GP G
Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGPPGPR---GRSGETG--------PAGPPGNPGPPGPPG 1212
Query: 626 PPGP 629
PPGP
Sbjct: 1213 PPGP 1216
Score = 76.6 bits (187), Expect = 7e-14
Identities = 121/412 (29%), Positives = 141/412 (34%), Gaps = 65/412 (15%)
Query: 274 RQDHPSSMGVYGQESG-GFSGP-GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 331
R P G GQ GF GP G N +G RG + G G G G
Sbjct: 586 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 645
Query: 332 ----AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK 387
AGERG PG +G GPP + + D G V F
Sbjct: 646 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 705
Query: 388 QCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV 447
+ G G + G P D P A + G +
Sbjct: 706 ERGSPGAQGLQGPRGL-------PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA 758
Query: 448 SLARKKPPMNSM--RG--GLPPREG-RGMPPPLRGGPGGPGG---------PGGPMGRMG 493
+A K + +G G P ++G RG+ P+ GP GP G P GP G G
Sbjct: 759 GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAG 816
Query: 494 GRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC-GNQNFAWRTECNQCKA 550
RG G+RG P GP G G P G PG G Q A + A
Sbjct: 817 ARGAPGERGETGPPGPAGFAGPPGADGQ------------PGAKGEQGEAGQK--GDAGA 862
Query: 551 PKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFR 605
P P+G P P P G G GP G RG +G G PG R G G G G
Sbjct: 863 PGPQG--PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP 920
Query: 606 GGRGMD-----RGGFG-GGRRG-----GPGGPPGPLMEQ-MGGRRGGRGGPG 645
G G D RG G GR G GP GPPG E G G G PG
Sbjct: 921 GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 972
Score = 67.4 bits (163), Expect = 4e-11
Identities = 74/241 (30%), Positives = 88/241 (36%), Gaps = 70/241 (29%)
Query: 465 PREGRGMPPPLRG--GPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNV 520
P+ +G P ++ GP GP GP GP G G RG GD+G GPRG G P GN
Sbjct: 102 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP 161
Query: 521 QHRAGDWQCPNPGCGNQNFAW---------------------------RTECNQCKAPKP 553
PG G NFA R AP P
Sbjct: 162 GPPGPPGPPGPPGLGG-NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGP 220
Query: 554 EGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG----------- 602
+GF P P G+ G GP G RG G G G + G+ G+RG
Sbjct: 221 QGFQGNPGEP--GEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFP 278
Query: 603 ---------GFRGGRGMD--RGGFGG----GRRGGPG--GPPGPLMEQMGGRRGGRGGPG 645
G RG G+D +G G G G PG G PGP+ G RG PG
Sbjct: 279 GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM--------GPRGLPG 330
Query: 646 K 646
+
Sbjct: 331 E 331
Score = 50.8 bits (120), Expect = 4e-06
Identities = 61/195 (31%), Positives = 72/195 (36%), Gaps = 45/195 (23%)
Query: 478 GPGGPGGPGGPMGRMGGRGGDRGGFPPRGP------RGSRGNPSGGGNVQHRAGDWQCPN 531
G GP G G G + G +G P+GP RG RG+ G R D +
Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157
Query: 532 PGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP-----------PGGDRGRGGP--GGMRG 578
PG P P G PP PP G D GG G M+G
Sbjct: 158 PG----------------NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG 201
Query: 579 GRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRR 638
G + RG PG G G + GF+G G + G G GP GPPGP G+
Sbjct: 202 PMGPMGPRGPPG---PAGAPGPQ-GFQGNPG-EPGEPGVSGPMGPRGPPGP-----PGKP 251
Query: 639 GGRGGPGKMDKGEHR 653
G G GK K R
Sbjct: 252 GDDGEAGKPGKAGER 266
Score = 35.8 bits (81), Expect = 0.13
Identities = 38/152 (25%), Positives = 52/152 (34%), Gaps = 20/152 (13%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS----QAPSQYSQQSSSYGQQSSFRQD 276
G P G G + G Q P G+ Q P ++ G++ +
Sbjct: 1074 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL--KG 1131
Query: 277 HPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG----- 331
H G+ G G GP ++ SGP RG G + G+ G G G
Sbjct: 1132 HRGFTGLQGLP--GPPGPSGDQGASGPAGPSGPRG--PPGPVGPSGKDGANGIPGPIGPP 1187
Query: 332 -----AGERGGFNKPGGPMDEGPDLDLGPPVD 358
+GE G PG P GP GP +D
Sbjct: 1188 GPRGRSGETGPAGPPGNPGPPGPPGPPGPGID 1219
Score = 35.0 bits (79), Expect = 0.22
Identities = 92/426 (21%), Positives = 124/426 (29%), Gaps = 64/426 (15%)
Query: 111 VTTTQASYAAQSAYGTQPAYPAYGQ--QPAATAPTRPQDGNKPTETSQPQSSTGGYNQPS 168
VT + + AQ G A G+ P + P P+ P+ + G P
Sbjct: 880 VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 939
Query: 169 LGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQ 228
G+ P P +P PS + Q Q+ G P G+
Sbjct: 940 RA-GEPGLQGPAGPPGEKGEPGDDGPS-------GAEGPPGPQGLAGQRGIVGLPGQRGE 991
Query: 229 QSSYGQQSSYGQQPPTSYPPQTGSYSQ----APSQYSQQSSSYGQQSSFRQDHP----SS 280
+ G G+ P +G P + + G++ S D P +
Sbjct: 992 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 1051
Query: 281 MGVYGQ--ESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGF 338
GV G E+G PG P G G G G +G MG G
Sbjct: 1052 AGVKGDRGETGAVGAPGAPGPPGSPGPAG------PTGKQGDRGEAGAQGPMGPSGPAGA 1105
Query: 339 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 398
GP +GP D G +P E +GL G +
Sbjct: 1106 RGIQGP--QGPRGDKGEAGEPGE---------RGLKG------------HRGFTGLQGLP 1142
Query: 399 GQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNS 458
G P P GD S P+ G + + P
Sbjct: 1143 GPP-----------GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG 1191
Query: 459 MRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGG 518
G P G P P GP GP GPG M G G G P + R + + GG
Sbjct: 1192 RSGETGPAGPPGNPGP--PGPPGPPGPGIDMSAFAGLGPREKG--PDPLQYMRADQAAGG 1247
Query: 519 NVQHRA 524
QH A
Sbjct: 1248 LRQHDA 1253
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 85.1 bits (209), Expect = 2e-16
Identities = 146/567 (25%), Positives = 182/567 (32%), Gaps = 84/567 (14%)
Query: 125 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGS 184
G Q A G Q P P +G KP + P G P L + +P GS
Sbjct: 585 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP----GEAGAPGLVGPRGERGFPGERGS 640
Query: 185 YPMQPVTAPPSYP-------PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 237
Q + P P P S Q Q G+ + G G +
Sbjct: 641 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700
Query: 238 YGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGE 296
G++ P P + G P + + G++ P+ +G PGE
Sbjct: 701 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG------SAGARGAPGE 754
Query: 297 NRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGP 355
R +GP G GF G G+ G +G G AG++G PG +GP GP
Sbjct: 755 -RGETGPP----GPAGF-AGPPGADGQPGAKGEQGEAGQKGDAGAPG---PQGPSGAPGP 805
Query: 356 PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK-- 413
A QG + A + G N G P K+ K
Sbjct: 806 QGPTGVTGPKGARGAQGPPGATGFPGAAG---RVGPPGSNGNPGPPGPPGPSGKDGPKGA 862
Query: 414 -----PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GL 463
P G A P + G D A P + G GL
Sbjct: 863 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG------AEGPPGPQGLAGQRGIVGL 916
Query: 464 PPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 523
P + G P L G G PG G P G GDRG P GP G G G
Sbjct: 917 PGQRGERGFPGLPGPSGEPGKQGAP-----GASGDRGPPGPVGPPGLTGPAGEPGREGSP 971
Query: 524 AGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGG------DRGRGG----- 572
D G R E AP G PP P P G DRG G
Sbjct: 972 GADGPPGRDGAAGVK-GDRGETGAVGAPGAPG--PPGSPGPAGPTGKQGDRGEAGAQGPM 1028
Query: 573 -PGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGM--------DRGGFGGG 618
P G G RG +G G G G+RG GF G +G+ D+G G
Sbjct: 1029 GPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPA 1088
Query: 619 RRGGPGGPPGPLMEQMGGRRGGRGGPG 645
GP GPPGP+ G+ G G PG
Sbjct: 1089 GPSGPRGPPGPV--GPSGKDGANGIPG 1113
Score = 81.3 bits (199), Expect = 3e-15
Identities = 110/375 (29%), Positives = 130/375 (34%), Gaps = 47/375 (12%)
Query: 294 PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-GERGGFNKPGGPMDEGPDLD 352
PG+ + + GP +G G RG RG +G GA G RG +PG P + GP
Sbjct: 40 PGDIKDIVGPKGPPGPQGPAGEQG-PRGDRGD-KGEKGAPGPRGRDGEPGTPGNPGPPGP 97
Query: 353 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ-----PMIHIYL 407
GPP P + +A G ++ L G + G P
Sbjct: 98 PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN 157
Query: 408 DKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----G 462
E G+P + PP G D + K + R P RG G
Sbjct: 158 PGEPGEPGVSGPMGPRGPPGPPGK----PGDDGEAGKPGKAGERGPPGPQGARGFPGTPG 213
Query: 463 LPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNV 520
LP +G P L G G G PG G G G G G PRG G RG G
Sbjct: 214 LPGVKGHRGYPGLDGAKGEAGAPG-VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 272
Query: 521 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP-FPPPGGDRGRGGPGGMRGG 579
R D Q P P P P G P FP G +G GP G RG
Sbjct: 273 GARGNDGQ-PGPA---------------GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316
Query: 580 RGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRG--GPGGPPGPLME 632
G RG PG G G G G G +G G G GP GPPGP
Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP-QG 375
Query: 633 QMG--GRRGGRGGPG 645
G G +G G PG
Sbjct: 376 ATGPLGPKGQTGEPG 390
Score = 80.5 bits (197), Expect = 5e-15
Identities = 140/559 (25%), Positives = 180/559 (32%), Gaps = 100/559 (17%)
Query: 131 PAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG---SYPM 187
P + P A P P P+ G P N +PG S
Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 355
Query: 188 QPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYP 247
+ P +P + Q G GQ G G+Q P P
Sbjct: 356 PGIAGAPGFPGP-----------RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404
Query: 248 PQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG 307
G AP ++ G++ + + P +G G G G NR G D
Sbjct: 405 GPAGPQG-APGPAGEE----GKRGA--RGEPGGVGPIGPP--GERGAPGNRGFPGQDGLA 455
Query: 308 RGRGG-FDRGGMSRGGRGGGRGGMGA----GERGGFNKPGGPMDEGPDLDLGPPVDPDED 362
+G +RG G G G G G G G P D GP +GP P ED
Sbjct: 456 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 515
Query: 363 SDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY 422
QG GQP + + + G+ +
Sbjct: 516 GRPGPPGPQGAR------------------------GQPGVMGFPGPKGAN--GEPGKAG 549
Query: 423 EDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGP 482
E + GKD + PP + G +G P +G PG P
Sbjct: 550 EKGLPGAPGLRGLPGKDGE-------TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 602
Query: 483 GGPGGPMGRMGGRGGDRG-----GFPPR-GPRGSRGNPS--GGGNVQHRAGDWQCPN-PG 533
G PG GG+ GD+G G P GPRG RG P G Q G P PG
Sbjct: 603 GPPGE-----GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 657
Query: 534 CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMF 593
A P +G PP G+RG G G +G RG + ++G G
Sbjct: 658 TDGPKGA----SGPAGPPGAQG--PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 711
Query: 594 R-GGRG--------GDRG--GFRGGRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGR 637
+ GGRG G G G +G G G RG PG GPPGP G
Sbjct: 712 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP--AGFAGP 769
Query: 638 RGGRGGPG-KMDKGEHRQE 655
G G PG K ++GE Q+
Sbjct: 770 PGADGQPGAKGEQGEAGQK 788
Score = 77.4 bits (189), Expect = 4e-14
Identities = 139/548 (25%), Positives = 177/548 (32%), Gaps = 127/548 (23%)
Query: 117 SYAAQSAYG--TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQS 174
++AAQ A G + G P P+ P PQ G +P G+
Sbjct: 109 NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEP----GEP 164
Query: 175 NYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQ 234
S P P P PP P + +P + G P G + G
Sbjct: 165 GVSGPMGPRGPP-----GPPGKPGDDGEAGKP--------GKAGERGPPGPQGARGFPGT 211
Query: 235 QSSYGQQPPTSYPPQTGSYSQAPSQ-YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSG 293
G + YP G+ +A + +S S G+ S P MG G
Sbjct: 212 PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS-----PGPMGPRGL------- 259
Query: 294 PGENRSMSGPDNRGRGRGGFDRGGMSRG----GRGGGRGGMGA----GERGGFNKPGGPM 345
PGE R +GP RG + G + G GG G GA GE G G
Sbjct: 260 PGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 318
Query: 346 DEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI 405
+GP + G P P G + + D + G + G P
Sbjct: 319 AQGPRGEPGTPGSPGP---------AGASGNPGTDGIPGAKGSAGAPGIAGAPGFP---- 365
Query: 406 YLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPP 465
P+G PP + A K G +P + +G P
Sbjct: 366 -------GPRG--------PPGPQGATGPLGPKGQTG----------EPGIAGFKGEQGP 400
Query: 466 REGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHR 523
+ G P GP GP G GP G G RG G+ GG P GP G RG P
Sbjct: 401 K---GEP-----GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAP--------- 443
Query: 524 AGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPGGMRGGRGG 582
GN+ F P +G P P G G GP G G G
Sbjct: 444 -----------GNRGF-----------PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 481
Query: 583 LMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRR 638
+ G PG GR GD G G+ G G R GP GP G P + G +
Sbjct: 482 PGEPGLPGARGLTGRPGDAG--PQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK 539
Query: 639 GGRGGPGK 646
G G PGK
Sbjct: 540 GANGEPGK 547
Score = 77.0 bits (188), Expect = 5e-14
Identities = 118/424 (27%), Positives = 149/424 (35%), Gaps = 65/424 (15%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSS-FRQDHPS 279
GQP + G+Q GQ+ G P P Q P+ + + G Q P
Sbjct: 774 GQPGAKGEQGEAGQKGDAGAPGPQG--PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 831
Query: 280 SMGVYGQE-SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGA-GERGG 337
+ G G S G GP SG D RG D G R G G +G G GE+G
Sbjct: 832 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG--DSGPPGRAGEPGLQGPAGPPGEKG- 888
Query: 338 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 397
+PG D+GP GPP QGL + L + G +
Sbjct: 889 --EPG---DDGPSGAEGPPGP------------QGLAGQRGIVGLPGQRGERGFPGLPGP 931
Query: 398 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 457
+G+P GK +G S + P G + + + S PP
Sbjct: 932 SGEP----------GK-QGAPGASGDRGPPGPVGPPGLTGPAGEPGR-EGSPGADGPPGR 979
Query: 458 SMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRG- 512
G+ G G PG PG PG GP G+ G RG G +G P GP G+RG
Sbjct: 980 DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1039
Query: 513 -NPSGGGNVQHRAGDWQCPNPG----CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG-- 565
P G + AG+ PG G++ F P + P P G
Sbjct: 1040 QGPQGPRGDKGEAGE-----PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1094
Query: 566 GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGG 625
G G GP G G G G PG GR G+ G G G GP G
Sbjct: 1095 GPPGPVGPSGKDGANGIPGPIGPPGPR---GRSGETG--------PAGPPGNPGPPGPPG 1143
Query: 626 PPGP 629
PPGP
Sbjct: 1144 PPGP 1147
Score = 76.6 bits (187), Expect = 7e-14
Identities = 121/412 (29%), Positives = 141/412 (34%), Gaps = 65/412 (15%)
Query: 274 RQDHPSSMGVYGQESG-GFSGP-GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 331
R P G GQ GF GP G N +G RG + G G G G
Sbjct: 517 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 576
Query: 332 ----AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK 387
AGERG PG +G GPP + + D G V F
Sbjct: 577 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 636
Query: 388 QCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV 447
+ G G + G P D P A + G +
Sbjct: 637 ERGSPGAQGLQGPRGL-------PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA 689
Query: 448 SLARKKPPMNSM--RG--GLPPREG-RGMPPPLRGGPGGPGG---------PGGPMGRMG 493
+A K + +G G P ++G RG+ P+ GP GP G P GP G G
Sbjct: 690 GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAG 747
Query: 494 GRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC-GNQNFAWRTECNQCKA 550
RG G+RG P GP G G P G PG G Q A + A
Sbjct: 748 ARGAPGERGETGPPGPAGFAGPPGADGQ------------PGAKGEQGEAGQK--GDAGA 793
Query: 551 PKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFR 605
P P+G P P P G G GP G RG +G G PG R G G G G
Sbjct: 794 PGPQG--PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP 851
Query: 606 GGRGMD-----RGGFG-GGRRG-----GPGGPPGPLMEQ-MGGRRGGRGGPG 645
G G D RG G GR G GP GPPG E G G G PG
Sbjct: 852 GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 903
Score = 67.4 bits (163), Expect = 4e-11
Identities = 74/241 (30%), Positives = 88/241 (36%), Gaps = 70/241 (29%)
Query: 465 PREGRGMPPPLRG--GPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNV 520
P+ +G P ++ GP GP GP GP G G RG GD+G GPRG G P GN
Sbjct: 33 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP 92
Query: 521 QHRAGDWQCPNPGCGNQNFAW---------------------------RTECNQCKAPKP 553
PG G NFA R AP P
Sbjct: 93 GPPGPPGPPGPPGLGG-NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGP 151
Query: 554 EGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG----------- 602
+GF P P G+ G GP G RG G G G + G+ G+RG
Sbjct: 152 QGFQGNPGEP--GEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFP 209
Query: 603 ---------GFRGGRGMD--RGGFGG----GRRGGPG--GPPGPLMEQMGGRRGGRGGPG 645
G RG G+D +G G G G PG G PGP+ G RG PG
Sbjct: 210 GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM--------GPRGLPG 261
Query: 646 K 646
+
Sbjct: 262 E 262
Score = 35.8 bits (81), Expect = 0.13
Identities = 38/152 (25%), Positives = 52/152 (34%), Gaps = 20/152 (13%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS----QAPSQYSQQSSSYGQQSSFRQD 276
G P G G + G Q P G+ Q P ++ G++ +
Sbjct: 1005 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL--KG 1062
Query: 277 HPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG----- 331
H G+ G G GP ++ SGP RG G + G+ G G G
Sbjct: 1063 HRGFTGLQGLP--GPPGPSGDQGASGPAGPSGPRG--PPGPVGPSGKDGANGIPGPIGPP 1118
Query: 332 -----AGERGGFNKPGGPMDEGPDLDLGPPVD 358
+GE G PG P GP GP +D
Sbjct: 1119 GPRGRSGETGPAGPPGNPGPPGPPGPPGPGID 1150
Score = 35.0 bits (79), Expect = 0.22
Identities = 92/426 (21%), Positives = 124/426 (29%), Gaps = 64/426 (15%)
Query: 111 VTTTQASYAAQSAYGTQPAYPAYGQ--QPAATAPTRPQDGNKPTETSQPQSSTGGYNQPS 168
VT + + AQ G A G+ P + P P+ P+ + G P
Sbjct: 811 VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 870
Query: 169 LGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQ 228
G+ P P +P PS + Q Q+ G P G+
Sbjct: 871 RA-GEPGLQGPAGPPGEKGEPGDDGPS-------GAEGPPGPQGLAGQRGIVGLPGQRGE 922
Query: 229 QSSYGQQSSYGQQPPTSYPPQTGSYSQ----APSQYSQQSSSYGQQSSFRQDHP----SS 280
+ G G+ P +G P + + G++ S D P +
Sbjct: 923 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 982
Query: 281 MGVYGQ--ESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGF 338
GV G E+G PG P G G G G +G MG G
Sbjct: 983 AGVKGDRGETGAVGAPGAPGPPGSPGPAG------PTGKQGDRGEAGAQGPMGPSGPAGA 1036
Query: 339 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 398
GP +GP D G +P E +GL G +
Sbjct: 1037 RGIQGP--QGPRGDKGEAGEPGE---------RGLKG------------HRGFTGLQGLP 1073
Query: 399 GQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNS 458
G P P GD S P+ G + + P
Sbjct: 1074 GPP-----------GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG 1122
Query: 459 MRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGG 518
G P G P P GP GP GPG M G G G P + R + + GG
Sbjct: 1123 RSGETGPAGPPGNPGP--PGPPGPPGPGIDMSAFAGLGPREKG--PDPLQYMRADQAAGG 1178
Query: 519 NVQHRA 524
QH A
Sbjct: 1179 LRQHDA 1184
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 83.6 bits (205), Expect = 5e-16
Identities = 92/327 (28%), Positives = 137/327 (41%), Gaps = 40/327 (12%)
Query: 26 TQGYAQTTQAYGQQSYGTYGQPTDVS--YTQ--AQTTATYGQ----TAYATSYGQPPTVE 77
+ G+ Q Q SYG +G + S Y Q ++ T+ +GQ + +T +GQ +
Sbjct: 528 SSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGS 587
Query: 78 GTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQP 137
G S+G+ Q S Q G G +++ + Q+SY S+ +Q + YGQ
Sbjct: 588 GQSSGFG-----QHGSGSGQSSGFGQHESRSG-----QSSYGQHSSGSSQSS--GYGQHG 635
Query: 138 AATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYP 197
+ Q G+ ++++ G Q S G+GQ Q G + + SY
Sbjct: 636 SRQTSGFGQHGSGSSQSTGFGQYGSGSGQSS-GFGQHVSGSGQSSGFGQHESRSGHSSYG 694
Query: 198 PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQS-SYGQQSSYGQQPPTSYPPQTGSYSQA 256
+ S+Q + Y Q S GQ S +GQ S GQ SS+GQ GS S
Sbjct: 695 QHGFGSSQSSGYGQHGSSS----GQTSGFGQHELSSGQSSSFGQH---------GSGSGQ 741
Query: 257 PSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRG 316
S + Q S GQ S F Q S GQ S G G ++S + R GF +
Sbjct: 742 SSGFGQHGSGSGQSSGFGQHESRS----GQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQH 797
Query: 317 GM-SRGGRGGGRGGMGAGERGGFNKPG 342
G S G G+ G G+G+ GF + G
Sbjct: 798 GSGSSQSTGFGQYGSGSGQSAGFGQHG 824
Score = 80.9 bits (198), Expect = 4e-15
Identities = 98/362 (27%), Positives = 147/362 (40%), Gaps = 48/362 (13%)
Query: 3 STDYSTYSQAAAQQ-GYSAYTAQPTQ--GYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTA 59
ST + Y + Q G+ + + Q G+ Q G SYG +G + S Q +
Sbjct: 652 STGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGS 711
Query: 60 TYGQTA----------YATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTA 109
+ GQT+ ++S+GQ + G S+G+ Q S Q G G +++ +
Sbjct: 712 SSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFG-----QHGSGSGQSSGFGQHESRSG 766
Query: 110 TVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSL 169
Q+SY S+ +Q + YGQ + Q G+ ++++ G Q S
Sbjct: 767 -----QSSYGQHSSGSSQSS--GYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQ-SA 818
Query: 170 GYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYG-------- 221
G+GQ Q G + + SY S+Q + Y Q S T G
Sbjct: 819 GFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSS 878
Query: 222 -QPSSYGQQ-SSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPS 279
Q S +GQ S GQ S +GQ S Q + Q S+ Q SSYGQ S S
Sbjct: 879 GQYSGFGQHGSGSGQSSGFGQHGTGS--GQYSGFGQHESRSHQ--SSYGQHGS-GSSQSS 933
Query: 280 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGG-GRGGMGAGERGGF 338
G +G SG G G++RS SG + GF + G G G G+ G+G+ GF
Sbjct: 934 GYGQHGSSSGQTFGFGQHRSGSGQSS------GFGQHGSGSGQSSGFGQHESGSGKSSGF 987
Query: 339 NK 340
+
Sbjct: 988 GQ 989
Score = 78.6 bits (192), Expect = 2e-14
Identities = 101/392 (25%), Positives = 152/392 (38%), Gaps = 54/392 (13%)
Query: 4 TDYSTYSQAAAQQ-GYSAY--TAQPTQGYAQTTQAYGQQS-YGTYGQPTDVSYTQAQTTA 59
+ Y + ++Q GY + ++ T G+ Q + GQ S +G +G + S Q
Sbjct: 843 SSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGT 902
Query: 60 TYGQ---------TAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTAT 110
GQ ++ +SYGQ + S+GY Q S Q +G G + + +
Sbjct: 903 GSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYG-----QHGSSSGQTFGFGQHRSGSG- 956
Query: 111 VTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLG 170
Q+S Q G+ + +GQ + + + ++ + G + S G
Sbjct: 957 ----QSSGFGQHGSGSGQS-SGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSG 1011
Query: 171 YGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNT-YGQPSSYGQQ 229
YGQ S Q G + + S + S S + Q T GQ S +GQ
Sbjct: 1012 YGQHGSSSGQTTGFGQHRSSSGQYS----GFGQHGSGSDQSSGFGQHGTGSGQSSGFGQY 1067
Query: 230 SSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHP-----SSMGVY 284
S +QSSYGQ GS S S Y Q S+ GQ S F Q P S G Y
Sbjct: 1068 ESRSRQSSYGQH---------GSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQY 1118
Query: 285 GQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGP 344
G SG SG G++ S +G + GF + G G+ G G+ + G +
Sbjct: 1119 GSGSGQSSGFGQHGSGTGKSS------GFAQHEYRSGQSSYGQHGTGSSQSSGCGQ--HE 1170
Query: 345 MDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDS 376
GP G V SDN + Q ++DS
Sbjct: 1171 SGSGPTTSFGQHV---SGSDNFSSSGQHISDS 1199
Score = 76.6 bits (187), Expect = 7e-14
Identities = 97/367 (26%), Positives = 148/367 (40%), Gaps = 64/367 (17%)
Query: 4 TDYSTYSQAAAQQ-GYSAYTAQPTQGYAQTTQAYGQQS-YGTYGQPTDVSYTQAQTTATY 61
+ Y + ++Q GY Y ++ T G+ Q GQ + +G YG + S Q +
Sbjct: 541 SSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGS 600
Query: 62 GQTAY---------ATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVT 112
GQ++ +SYGQ + S+GY Q S+ G+G ++ +T
Sbjct: 601 GQSSGFGQHESRSGQSSYGQHSSGSSQSSGYG-----QHGSRQTSGFGQHGSGSSQSTGF 655
Query: 113 TTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGY---NQPSL 169
S + QS+ +GQ + + + G E+ SS G + + S
Sbjct: 656 GQYGSGSGQSS--------GFGQHVSGSGQS---SGFGQHESRSGHSSYGQHGFGSSQSS 704
Query: 170 GYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQ--SSYSQQNTYGQPSS-Y 226
GYGQ S Q G + SS Q +S+ Q S Q + +GQ S
Sbjct: 705 GYGQHGSSSGQTSG------------FGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGS 752
Query: 227 GQQSSYGQ------QSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
GQ S +GQ QSSYGQ +S Q+ Y Q S+Q+S +GQ S +
Sbjct: 753 GQSSGFGQHESRSGQSSYGQH--SSGSSQSSGYGQ---HGSRQTSGFGQHGS-GSSQSTG 806
Query: 281 MGVYGQESGGFSGPGENRSMSGP-------DNRGRGRGGFDRGGMSRGGRGGGRGGMGAG 333
G YG SG +G G++ S SG ++R G S G G+ G +G
Sbjct: 807 FGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSG 866
Query: 334 ERGGFNK 340
+ GF +
Sbjct: 867 QTSGFGQ 873
Score = 75.9 bits (185), Expect = 1e-13
Identities = 96/363 (26%), Positives = 141/363 (38%), Gaps = 54/363 (14%)
Query: 17 GYSAYTAQPTQGYAQTTQAYGQQS-YGTYGQPTDVSYTQAQTTATYGQTAYATSYGQPPT 75
G T+ + GY Q + G+ S +G +G + S Q + GQ++ +GQ +
Sbjct: 454 GQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSS---GFGQHGS 510
Query: 76 VEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPA-YPAYG 134
V G S+G+ Q S Q G G +++ + Q+SY + +Q + Y YG
Sbjct: 511 VSGQSSGFG-----QHGSVSGQSSGFGQHESRSR-----QSSYGQHGSGSSQSSGYGQYG 560
Query: 135 QQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPP 194
+ + + T Q S +G S G+GQ Q G + +
Sbjct: 561 SRETSGFGQHGLGSGQSTGFGQYGSGSG----QSSGFGQHGSGSGQSSGFGQHESRSGQS 616
Query: 195 SYPPTSYSSTQPTSYDQ------------SSYSQQNT--------YGQPSSYGQQ-SSYG 233
SY S S+Q + Y Q S S Q+T GQ S +GQ S G
Sbjct: 617 SYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSG 676
Query: 234 QQSSYGQQPPTSYPPQTGSYSQAPSQ---YSQQSSSYGQQSSFRQDH-----PSSMGVYG 285
Q S +GQ S G + SQ Y Q SS GQ S F Q SS G +G
Sbjct: 677 QSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHG 736
Query: 286 QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPM 345
SG SG G++ S SG + GF + G G+ G+ + G+ + G
Sbjct: 737 SGSGQSSGFGQHGSGSGQSS------GFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQ 790
Query: 346 DEG 348
G
Sbjct: 791 TSG 793
Score = 59.7 bits (143), Expect = 8e-09
Identities = 88/362 (24%), Positives = 139/362 (38%), Gaps = 62/362 (17%)
Query: 16 QGYSAYTAQPTQGYAQT-----TQAYGQQSYGTY--GQPTD------VSYTQAQTTATYG 62
QG+ + G Q +Q+Y Q+ YG GQP + +Q+ YG
Sbjct: 325 QGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYG 384
Query: 63 QT-AYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQ 121
+ + S GQ G+ ++ ++ +S+ Q YG+G+ +T+ T S ++
Sbjct: 385 SGGSQSCSNGQHEY--GSCGRFSNSSSSNEFSKCDQ-YGSGSSQSTSFEQHGTGLSQSSG 441
Query: 122 SAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQV 181
+ GQ + ++ + D + T G+ Q G GQS+
Sbjct: 442 FEQHVCGSGQTCGQHESTSSQSLGYD-----QHGSSSGKTSGFGQHGSGSGQSS------ 490
Query: 182 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQ--SSYSQQNTYGQPSSY-GQQSSYGQ---- 234
+ S Q + + Q S Q + +GQ S GQ S +GQ
Sbjct: 491 -------------GFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESR 537
Query: 235 --QSSYGQQ-PPTSYPPQTGSY-SQAPSQYSQQSSSYGQQSSFRQ-----DHPSSMGVYG 285
QSSYGQ +S G Y S+ S + Q GQ + F Q S G +G
Sbjct: 538 SRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHG 597
Query: 286 QESGGFSGPGENRSMSGPDNRGRGRGGFDRGG-----MSRGGRGGGRGGMGAGERGGFNK 340
SG SG G++ S SG + G+ G + SR G G+ G G+ + GF +
Sbjct: 598 SGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQ 657
Query: 341 PG 342
G
Sbjct: 658 YG 659
Score = 54.3 bits (129), Expect = 4e-07
Identities = 86/379 (22%), Positives = 135/379 (35%), Gaps = 77/379 (20%)
Query: 3 STDYSTYSQAAAQQ---GYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQ--- 56
S+ + Y + Q G + G+AQ GQ SYG +G + S Q
Sbjct: 1112 SSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHES 1171
Query: 57 ---TTATYGQ-----------------TAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPV 96
T ++GQ + +T +GQ + G STG Q SQ V
Sbjct: 1172 GSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTG-----LGQGESQQV 1226
Query: 97 QGYGT--GAYDTTTA-TVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTE 153
+ T G +TT T+ TT+ S + Q GQ Q G++ T
Sbjct: 1227 ESGSTVHGRQETTHGQTINTTRHSQSGQ------------GQS--------TQTGSRVTR 1266
Query: 154 TSQPQSSTGGYNQ--PSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQ 211
+ S ++ + + S + + Q YP T T T +
Sbjct: 1267 RRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGH 1326
Query: 212 SSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPP--QTGSYSQAPSQYSQQSSSYGQ 269
S + Q G +S Q+ S+ + S+ P Q ++SQA SQ+ +
Sbjct: 1327 SGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGE------S 1380
Query: 270 QSSFRQDHPSSMGVYGQESG-GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGG--- 325
+S+ + H ++ G G+ +G G SG G++ + G GR G S GG
Sbjct: 1381 ESTVHERHETTYGQTGEATGHGHSGHGQS-TQRGSRTTGRRGSGHSESSDSEVHSGGSHR 1439
Query: 326 --------GRGGMGAGERG 336
G+ G GE G
Sbjct: 1440 PQSQEQTHGQAGSQHGESG 1458
Score = 47.8 bits (112), Expect = 3e-05
Identities = 87/371 (23%), Positives = 126/371 (33%), Gaps = 57/371 (15%)
Query: 8 TYSQAAAQQGYSAYTA----QPTQGYAQTTQAYGQQSYG--------TYGQ--------- 46
T+SQA +Q G S T Q T G T +G S+G T G+
Sbjct: 1900 THSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYS 1959
Query: 47 ----PTDVSYTQAQTTATYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTG 102
P+ VS+T + T + Y S GT+ G T T +S G T
Sbjct: 1960 DSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSG--HGQSTQ 2017
Query: 103 AYDTTTATVTTTQASYAAQSAY-GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSST 161
TT + + Y+ + G + + A + Q G + + +T
Sbjct: 2018 RGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGS-----QHGESGSSVHERHGTT 2072
Query: 162 GGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYG 221
G + + S + GS TA S SS S +TYG
Sbjct: 2073 HGQTGDTTRHAHSGHGQSTQRGSR-----TAGRRGSGHSESSDSEVHSGVSHTHSGHTYG 2127
Query: 222 QP-SSYGQQSS--YGQQSS-YGQQPPTS--------YPPQTGSYSQAPSQYSQQSSS--- 266
Q S +G+ S +G+Q + +GQ T+ QTGS + + S SS
Sbjct: 2128 QARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSE 2187
Query: 267 -YGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGP--DNRGRGRGGFDRGGMSRGGR 323
+ + S H S G SG G + G D G+ + RG R
Sbjct: 2188 VHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQ-STQRGSR 2246
Query: 324 GGGRGGMGAGE 334
GR G G E
Sbjct: 2247 TTGRRGSGHSE 2257
Score = 40.8 bits (94), Expect = 0.004
Identities = 59/284 (20%), Positives = 113/284 (39%), Gaps = 33/284 (11%)
Query: 8 TYSQAAAQQGYSAYTAQPTQG--YAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYGQTA 65
T+SQA +Q G S T Y QT +A G G +GQ T ++TT G
Sbjct: 1369 THSQAGSQHGESESTVHERHETTYGQTGEATGHGHSG-HGQSTQRG---SRTTGRRG--- 1421
Query: 66 YATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG 125
+ + + E S G P + + G + + +TV + Q+
Sbjct: 1422 --SGHSESSDSEVHSGGSHRPQS----QEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDT 1475
Query: 126 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGG-YNQPSLGYGQSNYSYPQVPGS 184
T+ A+ +G+ + T + G+ +E+S + +GG + +GQS + +
Sbjct: 1476 TRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESI 1535
Query: 185 -YPMQPVTAPPSYPPTSYSST---------------QPTSYDQSSYSQQNTYGQPSSYGQ 228
+ +T + T +S + Q TS+ +S+ S+ ++ G + +
Sbjct: 1536 IHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSR 1595
Query: 229 QSSYGQQSSYGQQPPTSYPPQTG-SYSQAPSQYSQQSSSYGQQS 271
+ +YGQ S ++P + + G ++ Q S +GQ +
Sbjct: 1596 EHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQST 1639
Score = 39.7 bits (91), Expect = 0.009
Identities = 70/329 (21%), Positives = 119/329 (36%), Gaps = 33/329 (10%)
Query: 8 TYSQAAAQQGYSAYTAQPTQG--YAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYGQTA 65
TY QA +Q +T G + Q G S+ +GQ T Q + T Q +
Sbjct: 1598 TYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGH-SHSGHGQST-----QRGSRTTGRQRS 1651
Query: 66 YATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG 125
+ G S +T T QA SQ Q + + V + Q+
Sbjct: 1652 SHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQ---------SESIVPERHGTTHGQTGDT 1702
Query: 126 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSY 185
T+ A+ +G + T + G+ +E S + +G + + S +++ Q +
Sbjct: 1703 TRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSG------VSHTHSGHTHGQARSQH 1756
Query: 186 PMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQS-SYGQQPPT 244
+ + T + S + Q G ++ + S + + S S G +
Sbjct: 1757 GESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFS 1816
Query: 245 SYPPQTG-SYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG-GFSGPGENRSMSG 302
P G ++ QA SQ+ + S ++ H ++ G G SG SG G++ + SG
Sbjct: 1817 QRPHSRGHTHGQAGSQHGESESIVDER------HGTTHGQTGDTSGHSQSGHGQS-TQSG 1869
Query: 303 PDNRGRGRGGFDRGGMSRGGRGGGRGGMG 331
GR R G S GG G
Sbjct: 1870 SSTTGRRRSGHSESSDSEVHSGGSHTHSG 1898
Score = 38.1 bits (87), Expect = 0.026
Identities = 63/322 (19%), Positives = 112/322 (34%), Gaps = 33/322 (10%)
Query: 8 TYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVS----YTQAQTTATYGQ 63
T+ QA +Q G S G T+GQ D + Y TT T +
Sbjct: 1673 THGQAGSQHGQSESIVPERHGT-------------THGQTGDTTRHAHYHHGLTTQTGSR 1719
Query: 64 TAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSA 123
T G + S GY+ + +S G + + + V + Q+
Sbjct: 1720 TTGRRGSGHSEYSD--SEGYSGVS--HTHSGHTHGQARSQHGESESIVHERHGTIHGQTG 1775
Query: 124 YGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG 183
T+ A+ +GQ + T + + +E S + +G +P +++ Q G
Sbjct: 1776 DTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPH----SRGHTHGQA-G 1830
Query: 184 SYPMQPVTAPPSYPPTSYSSTQPTS-YDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQP 242
S + + T++ T TS + QS + Q G ++ ++S + + S
Sbjct: 1831 SQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHS 1890
Query: 243 PTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSG 302
S+ ++SQA SQ+ + S+ ++ +G S G +G
Sbjct: 1891 GGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHG------QTIQTG 1944
Query: 303 PDNRGRGRGGFDRGGMSRGGRG 324
GR G S G G
Sbjct: 1945 SRTTGRRGSGHSEYSDSEGPSG 1966
Score = 30.4 bits (67), Expect = 5.4
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Query: 587 GGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRG 639
GG G F + G + G +GG+G G GG+ G G P Q +RG
Sbjct: 304 GGQGNQFSYIQSGCQSGIKGGQG--HGCVSGGQPSGCGQPESNPCSQSYSQRG 354
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 83.2 bits (204), Expect = 7e-16
Identities = 81/215 (37%), Positives = 83/215 (38%), Gaps = 41/215 (19%)
Query: 470 GMPPPLRG------GPGGP-------GGPG---GPMGR-MGGRGGDRGGFPPRGPRGSRG 512
G PPP RG GPG P GGPG GP R GGRGG+ PP RG+RG
Sbjct: 668 GPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARG 727
Query: 513 NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG- 571
SGGG R G PG G P PGG G G
Sbjct: 728 GRSGGGPPNGRGG------PGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGH 781
Query: 572 ----GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRR--GGPGG 625
GPGG GG GG GPGG GG G R G GM G GGG R GPGG
Sbjct: 782 RPHEGPGGSMGGGGGHRPHEGPGGGISGG-SGHRPHEGPGGGM---GAGGGHRPHEGPGG 837
Query: 626 PPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 660
MGG G R G G H D P
Sbjct: 838 -------SMGGSGGHRPHEGPGHGGPHGHRPHDVP 865
Score = 72.0 bits (175), Expect = 2e-12
Identities = 71/206 (34%), Positives = 74/206 (35%), Gaps = 64/206 (31%)
Query: 472 PPPLRGG--PGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQC 529
P P+ G PGGPGGP G G GG P GP G G P G
Sbjct: 622 PGPIANGFPPGGPGGPKGMQHFPPGPGG-----PMPGPHGGPGGPVG------------- 663
Query: 530 PNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGG-MRGG--RGGLMDR 586
P+ L PP PP GGD GPG MRGG RGG
Sbjct: 664 ---------------------PR---LLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPG 699
Query: 587 GGPGGMFRGGRGGDR-----GGFRGGRGMDRGGFGGGRRGGPGG------------PPGP 629
GP RGGRGG+ FRG RG GG RGGPGG PG
Sbjct: 700 PGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGG 759
Query: 630 LMEQMGGRRGGRGGPGKMDKGEHRQE 655
M G R G G M G E
Sbjct: 760 GMGNSSGHRPHEGPGGGMGSGHRPHE 785
Score = 59.7 bits (143), Expect = 8e-09
Identities = 82/225 (36%), Positives = 90/225 (40%), Gaps = 60/225 (26%)
Query: 477 GGPGG-PGGPGGPM------GRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQH-RAGDWQ 528
GG GG P G GG MG G +G P+GP G GG NVQ
Sbjct: 540 GGSGGSPDGAGGSKLPPVLANLMGSMGAGKG---PQGPGG------GGINVQEILTSIMG 590
Query: 529 CPNPGCGNQNFAWRTECNQCKAP-KPEGFLPP-----PFPP--PGGDRGR----GGPGG- 575
PN + ++ K P G L P FPP PGG +G GPGG
Sbjct: 591 SPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP 650
Query: 576 MRGGRGGLMDRGGPGGMFRGG-----RGGD----------RGG-FRGGRGMDRGGF--GG 617
M G GG GGP G G RGGD RGG RGG G G + G
Sbjct: 651 MPGPHGG---PGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGR 707
Query: 618 GRRGG--PGGPPGPLMEQMGGRRG-----GRGGP--GKMDKGEHR 653
G RGG P PP P GGR G GRGGP G + G HR
Sbjct: 708 GGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHR 752
Score = 33.9 bits (76), Expect = 0.49
Identities = 25/74 (33%), Positives = 27/74 (36%), Gaps = 2/74 (2%)
Query: 271 SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGM 330
SS + H G G GPG + G G GG GG G GGM
Sbjct: 764 SSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGM 823
Query: 331 GAGERGGFNKPGGP 344
GAG GG GP
Sbjct: 824 GAG--GGHRPHEGP 835
Score = 33.9 bits (76), Expect = 0.49
Identities = 28/74 (37%), Positives = 29/74 (39%), Gaps = 8/74 (10%)
Query: 289 GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGG----- 343
GG SG +R GP G G GG R GG GG GG E G P G
Sbjct: 805 GGISGGSGHRPHEGPGG-GMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHD 863
Query: 344 -PMDEGPDLDLGPP 356
P G D GPP
Sbjct: 864 VPGHRGHD-HRGPP 876
Score = 32.7 bits (73), Expect = 1.1
Identities = 32/102 (31%), Positives = 35/102 (34%), Gaps = 30/102 (29%)
Query: 290 GFSGPGENRSMSGPDNRGRG-----------------RGGFDRGGMSRGGRGGGRGGMGA 332
G GPG GP +RGRG RGG GG G G G G +G
Sbjct: 694 GGPGPGP-----GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGG 748
Query: 333 GERGGFNKPGGPM--------DEGPDLDLGPPVDPDEDSDNS 366
G PGG M EGP +G P E S
Sbjct: 749 GGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGS 790
Score = 31.2 bits (69), Expect = 3.2
Identities = 33/119 (27%), Positives = 37/119 (31%), Gaps = 15/119 (12%)
Query: 239 GQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENR 298
G P P G P Y + G + P + GG SG G
Sbjct: 682 GPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGN-----EPPPPPPPFRGARGGRSGGGPPN 736
Query: 299 SMSGPDNRGRGRGGFDRGGMSRGGRG---------GGRGGMGAGERGGFNKPGGPMDEG 348
GP G GG GG G G GGMG+G R PGG M G
Sbjct: 737 GRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHR-PHEGPGGSMGGG 794
Score = 29.6 bits (65), Expect = 9.3
Identities = 25/64 (39%), Positives = 26/64 (40%), Gaps = 8/64 (12%)
Query: 289 GGFSGPGENRSMSGP------DNRGRGRGGFDRGGMSRGGRGGGRG--GMGAGERGGFNK 340
GG GP R + P D G G RGG RGG G G G G G RGG
Sbjct: 656 GGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEP 715
Query: 341 PGGP 344
P P
Sbjct: 716 PPPP 719
Score = 29.6 bits (65), Expect = 9.3
Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 5/74 (6%)
Query: 280 SMGVYG----QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGER 335
SMG G E G GP +R P +RG G RG G G GG G
Sbjct: 838 SMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRG-PPPHEHRGHDGPGHGGGGHRGH 896
Query: 336 GGFNKPGGPMDEGP 349
G + GG M P
Sbjct: 897 DGGHSHGGDMSNRP 910
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 82.0 bits (201), Expect = 2e-15
Identities = 138/533 (25%), Positives = 182/533 (34%), Gaps = 82/533 (15%)
Query: 178 YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 237
+P++PG + P P +P Q G P + GQ+ ++G +
Sbjct: 342 HPRMPGEQGPKGEKGDPGLPGEPGLQGRP-----GELGPQGPTGPPGAKGQEGAHGAPGA 396
Query: 238 YGQQ--------PPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG 289
G P S PP + + + ++ + P +G G
Sbjct: 397 AGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGA 456
Query: 290 -GFSGPGENRSMSGPDNRGR-------GRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKP 341
G GP P RG G G DRG G G RG G G G
Sbjct: 457 PGLPGPPGKGKDGEPGLRGSPGLPGPLGTKG-DRGAPGIPGSPGSRGDPGIGVAGPPGPS 515
Query: 342 GGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLA-DFFKQC-----GVVKMN 395
G P D+G G P P + L ++ LA D C G+ +
Sbjct: 516 GPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLP 575
Query: 396 KRTGQPMIHIYLDKE-TGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK- 453
G + +E T KG+A P A + G+ +G+ +V +
Sbjct: 576 GFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGE--RGADGEVGQKGDQG 633
Query: 454 ---------PPMNSMRGGLPPREGRGMPPPLRGGPG--GPGGPGGPMGRMG--------G 494
PP N G G PP ++G PG GP GP GP G G G
Sbjct: 634 HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG 693
Query: 495 RGGDRG--GFPPR-------GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 545
R G G G P + GP G+RG P G+ GD P P R E
Sbjct: 694 RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH----TGDSGAPGP---------RGES 740
Query: 546 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 605
P EG P GD G GP G +G RG G PG G G G +
Sbjct: 741 GAMGLPGQEG-----LPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQ-K 794
Query: 606 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRD 658
G +G + G G GP GPPG E+ G G G PGK + + ER D
Sbjct: 795 GSKG-ENGSPGLPGFLGPRGPPGEPGEK--GVPGKEGVPGKPGEPGFKGERGD 844
Score = 75.1 bits (183), Expect = 2e-13
Identities = 67/193 (34%), Positives = 80/193 (41%), Gaps = 36/193 (18%)
Query: 462 GLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMG--------GRGGDRGGFPPRGPRGSR 511
GLP EG PP +G G G PG G G MG G+ GD G P+GP+G R
Sbjct: 711 GLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 770
Query: 512 GNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP-------- 563
G P G+ PG + + +P GFL P PP
Sbjct: 771 GPPGKNGSPGSPGEPGPSGTPG-------QKGSKGENGSPGLPGFLGPRGPPGEPGEKGV 823
Query: 564 PGGDRGRGGPG-----GMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFG 616
PG + G PG G RG G D+G PGG G+ GD G G +G G+ G G
Sbjct: 824 PGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK---GQPGDPGIPGHKGHTGL-MGPQG 879
Query: 617 GGRRGGPGGPPGP 629
GP GPPGP
Sbjct: 880 LPGENGPVGPPGP 892
Score = 65.1 bits (157), Expect = 2e-10
Identities = 126/465 (27%), Positives = 158/465 (33%), Gaps = 80/465 (17%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
G P + G G++ G++ P G + +S HP
Sbjct: 286 GLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRM 345
Query: 281 MGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFDRGGMSRGGRGGGRGGMGA-GERGGF 338
G G + GE P G +GR G + G G G +G GA G G
Sbjct: 346 PGEQGPK-------GEKGDPGLPGEPGLQGRPG-ELGPQGPTGPPGAKGQEGAHGAPGAA 397
Query: 339 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 398
PG P G GPP ++ GL + D + G
Sbjct: 398 GNPGAPGHVGAPGPSGPP---------GSVGAPGLRGTPGKDG------ERGEKGAAGEE 442
Query: 399 GQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNS 458
G P P+GD P K GKD + R P +
Sbjct: 443 GSP--------GPVGPRGDPGAPGLPGPPGK-------GKDGEPG------LRGSPGLPG 481
Query: 459 MRGGLPPREGRGMP--PPLRGGPG-GPGGPGGPMGRMGGRG--GDRG--GFP-PRGPRGS 510
G R G+P P RG PG G GP GP G G +G G RG GFP P+GP G
Sbjct: 482 PLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGR 541
Query: 511 RGNPS--GGGNVQHRAGDW--QCPN-----PGC----GNQNFAWR-----TECNQCKAPK 552
G S G++ A D CP PG G++ + TE + +A
Sbjct: 542 DGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGP 601
Query: 553 PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM 610
P PP P G +G G G G +G G PG M G G G G G G
Sbjct: 602 PGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGP 661
Query: 611 DRGGFGGGRRG--GPGGPPG----PLMEQMGGRRGGRGGPGKMDK 649
G+ G GP GP G P E GR G G PG+ K
Sbjct: 662 PGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGK 706
Score = 63.9 bits (154), Expect = 4e-10
Identities = 124/476 (26%), Positives = 159/476 (33%), Gaps = 98/476 (20%)
Query: 211 QSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQ 270
Q S ++ G+ G Q G G P PP + A Q S G++
Sbjct: 614 QGSQGERGADGEVGQKGDQGHPGVPGFMGP-PGNPGPPGADGIAGAAGPPGIQGSP-GKE 671
Query: 271 SSFRQDHPSSM-GVYGQES-----GGFSGPGE-----NRSMSGPDNRGRGRGGFDRGGMS 319
PS + G+ G+E G PGE + GP+ RG GF +G
Sbjct: 672 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG-ARGPPGF-KGHTG 729
Query: 320 RGGRGGGRGGMGA----GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLND 375
G G RG GA G+ G K G GP GP P ++ + G +
Sbjct: 730 DSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSG 789
Query: 376 SVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWF 435
+ G G P + +L P+G E K V
Sbjct: 790 TP------------GQKGSKGENGSPGLPGFLG-----PRGPPGEPGEKGVPGKEGVPGK 832
Query: 436 DGKD-FQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRM 492
G+ F+G + G P +G PP +G PG PG PG G G M
Sbjct: 833 PGEPGFKGER-----------------GDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLM 875
Query: 493 GGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 550
G +G G+ G P GP G G P G + G Q T A
Sbjct: 876 GPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQ---LETRLAYLLA 932
Query: 551 PKPEGFLP-------PPFPP----------PGGDRGRGGPGGM---------RGGRGGLM 584
P ++ PP PP P G+ GR G GG+ +G RG
Sbjct: 933 QMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG 992
Query: 585 DRGGPGGMFRGGRGGDR-GGFRGGRGMDRGGFGG--------GRRGGPG--GPPGP 629
D G PG RG G G G G + G G G G PG GPPGP
Sbjct: 993 DPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGP 1048
Score = 55.8 bits (133), Expect = 1e-07
Identities = 112/468 (23%), Positives = 148/468 (31%), Gaps = 99/468 (21%)
Query: 131 PAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPV 190
P P P PQ + + G +P P +PG +
Sbjct: 662 PGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP---EGA 718
Query: 191 TAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQT 250
PP + + S P +S GQ G+ G G Q P P +
Sbjct: 719 RGPPGFKGHTGDSGAPGPRGESG--AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKN 776
Query: 251 GSYSQ----APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQ--ESGGFSGPGENRSMSGPD 304
GS PS Q S G+ S P +G G E G PG+ P
Sbjct: 777 GSPGSPGEPGPSGTPGQKGSKGENGS--PGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPG 834
Query: 305 NRG-RGRGGFDRGGMSRGGRGGGRGGMG-------AGERGGFNKPGGPMDEGPDLDLGPP 356
G +G G D G G GG+G G G G G P + GP +GPP
Sbjct: 835 EPGFKGERG-DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGP---VGPP 890
Query: 357 VDPDEDSDNSAIYVQGLN-DSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPK 415
P + GL +S +++ L ++ ++ K+ + ++
Sbjct: 891 GPPGQPG------FPGLRGESPSMETLRRLIQE----ELGKQLETRLAYLLAQM------ 934
Query: 416 GDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPL 475
PP + +K S R PP + GLP R G M P
Sbjct: 935 ---------PP----------------AYMKSSQGRPGPPGPPGKDGLPGRAGP-MGEPG 968
Query: 476 RGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG 533
R G GG GP GP+G G RG GD G P G RG G P G Q PG
Sbjct: 969 RPGQGGLEGPSGPIGPKGERGAKGDPGA-PGVGLRGEMGPPGIPG---------QPGEPG 1018
Query: 534 CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRG 581
P P P G+ G G G+ G G
Sbjct: 1019 YAKDGL-------------------PGIPGPQGETGPAGHPGLPGPPG 1047
Score = 38.1 bits (87), Expect = 0.026
Identities = 38/105 (36%), Positives = 44/105 (41%), Gaps = 24/105 (22%)
Query: 559 PPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG--GDRG-----GFRGGRGMD 611
P P G+ G G G G +G G PG F G RG GD+G G G +G D
Sbjct: 261 PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPG--FPGVRGEKGDQGEKGELGLPGLKG-D 317
Query: 612 RGGFGGGRRGGPGGPPG-----------PLMEQMGGRRGGRGGPG 645
RG G GP GPPG P M G +G +G PG
Sbjct: 318 RGEKG---EAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPG 359
>gi|153252068 testes-specific heterogenous nuclear ribonucleoprotein
G-T [Homo sapiens]
Length = 392
Score = 82.0 bits (201), Expect = 2e-15
Identities = 96/316 (30%), Positives = 117/316 (37%), Gaps = 73/316 (23%)
Query: 408 DKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPRE 467
D+ET K +G A V++E P AKAA +GK G +KV+ A KP S R G PP
Sbjct: 42 DRETNKSRGFAFVTFESPADAKAAARDMNGKSLDGKAIKVAQA-TKPAFESSRRGPPPPR 100
Query: 468 GRGMPPPLRGGPGGPGGPGGPMGRMGGRGG--DRGGF-------------------PPR- 505
RG P LRG GG GGP R RGG D GG+ PPR
Sbjct: 101 SRGRPRFLRGTRGGGGGP----RRSPSRGGPDDDGGYTADFDLRPSRAPMPMKRGPPPRR 156
Query: 506 -GPRGSRGNPSG-----GGNVQHRA------------------GDWQCPNPGCGNQNFAW 541
GP R PSG GG ++ RA + P G ++ ++
Sbjct: 157 VGPPPKRAAPSGPARSSGGGMRGRALAVRGRDGYSGPPRREPLPPRRDPYLGPRDEGYSS 216
Query: 542 RTECNQCKAPKPEGFLPPPFP---------------PPGGDRGRGGPGGMRGGRGGLMDR 586
R + +P GF P P P G R G GG G + R
Sbjct: 217 RDGYSSRDYREPRGFAPSPGEYTHRDYGHSSVRDDCPLRGYSDRDGYGGRDRDYGDHLSR 276
Query: 587 GGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 646
G F G+ G GRG GGGR G GGR G+
Sbjct: 277 GSHREPFES--YGELRGAAPGRGTPPSYGGGGRYEEYRGYSPDAYS--GGRDSYSSSYGR 332
Query: 647 MD---KGEHRQERRDR 659
D +G HR R DR
Sbjct: 333 SDRYSRGRHRVGRPDR 348
Score = 30.4 bits (67), Expect = 5.4
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 20/76 (26%)
Query: 296 ENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGG------------ 343
E+ P R RGR F RG RGGG G + RGG + GG
Sbjct: 90 ESSRRGPPPPRSRGRPRF-----LRGTRGGGGGPRRSPSRGGPDDDGGYTADFDLRPSRA 144
Query: 344 --PMDEG-PDLDLGPP 356
PM G P +GPP
Sbjct: 145 PMPMKRGPPPRRVGPP 160
>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
Length = 1669
Score = 80.5 bits (197), Expect = 5e-15
Identities = 150/562 (26%), Positives = 191/562 (33%), Gaps = 91/562 (16%)
Query: 128 PAYPAY-GQQPAATAPTRPQDGNKPTETSQPQS-STGGYNQPSLGYGQSNYSYPQVPGSY 185
P +P G A +P R P P S G P G G PGS
Sbjct: 546 PGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVG--------FPGSR 597
Query: 186 PMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTS 245
PP Y P + G P G G + G+ P
Sbjct: 598 GDTGPPGPPGYGPAG------------PIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLP 645
Query: 246 YPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSG-PD 304
PP +P Q + R P G GQ GF GP + + G P
Sbjct: 646 GPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPG 705
Query: 305 NRGR----GRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPD 360
+ G GR GF+ G G G +G G G G PG P G P P
Sbjct: 706 DMGPPGTPGRPGFN-GLPGNPGVQGQKGEPGVGLPGLKGLPGLP---------GIPGTPG 755
Query: 361 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIH-IYLDKETGKPKGDAT 419
E V G + ++ L + G + G P + I G P G
Sbjct: 756 EKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGP 815
Query: 420 VSYEDPPTAKAAVEW--FDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRG 477
PP K + F G D G K A+ P + + GLP G+ P + G
Sbjct: 816 PGLSGPPGIKGEKGFPGFPGLDMPGPKGDKG-AQGLPGITG-QSGLPGLPGQQGAPGIPG 873
Query: 478 GPGG---------PGGPG--GPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRA 524
PG PG PG GP+G G G GD GFP G G RG+P G+
Sbjct: 874 FPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDH-GFP--GSSGPRGDPGLKGD----K 926
Query: 525 GDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLM 584
GD P G + + K K + G++G+ GP G +G RG
Sbjct: 927 GDVGLP----GKPGSMDKVDMGSMKGQKGD----------QGEKGQIGPIGEKGSRG--- 969
Query: 585 DRGGPGGMFRGGRGGDRG--GFRGGRGMD----RGGFGG--GRRGGPGGPPGPLMEQMGG 636
D G PG + G+ G G G +G G+ G G G GG G P P + + G
Sbjct: 970 DPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPG 1029
Query: 637 RRGGRGGPG----KMDKGEHRQ 654
G +G PG K KGE Q
Sbjct: 1030 IPGPQGSPGLPGDKGAKGEKGQ 1051
Score = 69.3 bits (168), Expect = 1e-11
Identities = 123/478 (25%), Positives = 163/478 (34%), Gaps = 79/478 (16%)
Query: 205 QPTSYDQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQ 263
+P S D+ S + G GQ G++ S G P + G Q P Q +
Sbjct: 934 KPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQ-PGQPGPK 992
Query: 264 SSSYGQQSSFRQDHPSSMGVYGQES--GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRG 321
G + P + G+ G + GG PG P G +G
Sbjct: 993 GDP-GISGT-----PGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPG------PQGSPGLP 1040
Query: 322 GRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDD 381
G G +G G G PG ++G G P P E + +I + G+ S L
Sbjct: 1041 GDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKG 1100
Query: 382 LADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQ 441
G + G + LD G KG+A + PT A + G D
Sbjct: 1101 SPGSVGYPGSPGLPGEKGDKGLP-GLDGIPGV-KGEAGLPGTPGPTGPAGQKGEPGSD-- 1156
Query: 442 GSKLKVSLARKKPPMNSMRGGLPPREGRGMP--PPLRGGPGGPGGPGGPMGRMGGRG--- 496
+ S K P GLP GRG P P +G G G G P G G G
Sbjct: 1157 --GIPGSAGEKGEP------GLP---GRGFPGFPGAKGDKGSKGEVGFP-GLAGSPGIPG 1204
Query: 497 --GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE 554
G++G P GP+G G P G+ + P G P P
Sbjct: 1205 SKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGL-----------PGPM 1253
Query: 555 GFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG------------ 602
G PP P G +G G G G G +G PG G GG G
Sbjct: 1254 G--PPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPG 1311
Query: 603 --GFRGGRGM-----------DRGGFGGGRRGGPGGPPGP--LMEQMGGRRGGRGGPG 645
GF+G +G+ D+G G GP GPPGP +++ G G G PG
Sbjct: 1312 VPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPG 1369
Score = 67.0 bits (162), Expect = 5e-11
Identities = 75/218 (34%), Positives = 90/218 (41%), Gaps = 33/218 (15%)
Query: 462 GLPPREGRGMPPPLRGGPGGPG--------GPGGPMGRMG--GRGGDRGGFPPRGPRGSR 511
GLP +G PP G PG PG GP GP G G G G+RG P G G
Sbjct: 85 GLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFA 144
Query: 512 GNPSGGG--NVQHRAGDWQCPNPGC---GNQNFAWRTECNQCKAPKPEGF--LPPPFPPP 564
GNP G ++ G+ PG G + F P P G L P PP
Sbjct: 145 GNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFP-----GIPGTPGPPGLPGLQGPVGPP 199
Query: 565 G--GDRGRGGPGGMRGGRG--GLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFG---- 616
G G G GP G G +G GL +G G G G G + ++G F
Sbjct: 200 GFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGE 259
Query: 617 GGRRGGPG--GPPGPLMEQMGGRRGGRGGPGK-MDKGE 651
G++G PG G PG + G+ G RG PGK DKGE
Sbjct: 260 KGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGE 297
Score = 66.2 bits (160), Expect = 9e-11
Identities = 130/487 (26%), Positives = 169/487 (34%), Gaps = 80/487 (16%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQ-YSQQSSSYGQQSSFRQDHPS 279
G P G+Q G++ G P TG + + Y G+ + P
Sbjct: 308 GYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGP--KGFPG 365
Query: 280 SMGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFDR----GGMSRGGRGGGRGGMGAGE 334
G G G PG+ + P RG +G GF G R G G G G
Sbjct: 366 LPGQPGPP--GLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPG 423
Query: 335 RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN-DSVTLDDLADFFKQCGVVK 393
+ G+ GP D GPP P + I +G +S + D+ + G
Sbjct: 424 QPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQG 483
Query: 394 MNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGS---KLKVSLA 450
G P + G P D P + K G L++
Sbjct: 484 PPGEIGFPG-QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGD 542
Query: 451 RKKP-----PMNSMRGGLPPREGR-GMPPPLRGGPGGPG--GPGGPMGRMG--GRGGDRG 500
+ P P + R G P R+G G+P P +G PG G G GP G +G G GD G
Sbjct: 543 KGDPGFPGQPGMTGRAGSPGRDGHPGLPGP-KGSPGSVGLKGERGPPGGVGFPGSRGDTG 601
Query: 501 -----GFPPRGPRGSRGN---PSGGGNVQHRAGDWQ----CPNPGCGNQNFAWRTECNQC 548
G+ P GP G +G P G G+ + P PG
Sbjct: 602 PPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPG--------------- 646
Query: 549 KAPKPEGFLP--PPFPPPGGDRGRGGPGGMRG--------GRGGLMDRGGPGGMFRGGRG 598
P EG LP P FP P GDRG G G G G+ G+ G PG G
Sbjct: 647 -PPGAEG-LPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLP 704
Query: 599 GDRG-----GFRGGRGMDRGGFGGGRRGGPG-GPPG-------PLMEQMGGRRGGRGGPG 645
GD G G G G+ G++G PG G PG P + G +G G PG
Sbjct: 705 GDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPG 764
Query: 646 KMDKGEH 652
GEH
Sbjct: 765 V--PGEH 769
Score = 62.4 bits (150), Expect = 1e-09
Identities = 64/194 (32%), Positives = 80/194 (41%), Gaps = 38/194 (19%)
Query: 462 GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRG--GFPPRGPRGSRGNPSGGGN 519
GLP +G PP G PG PG PG P G++G G +GP+G +G+ G
Sbjct: 188 GLPGLQGPVGPPGFTGPPGPPGPPGPP--------GEKGQMGLSFQGPKGDKGD-QGVSG 238
Query: 520 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGG 579
G Q G +FA + E Q P GF P G+ G+ GP G G
Sbjct: 239 PPGVPGQAQVQEKG----DFATKGEKGQKGEP---GFQGMPGVGEKGEPGKPGPRGKPGK 291
Query: 580 RGGLMDRGGPGGMFRGGRGG--DRGGFRGGRGMDRGGFGGGRRGGPGGPP------GPLM 631
G ++G PG G G R G +G +G GP GPP GPL
Sbjct: 292 DGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKG----------EAGPPGPPGIVIGTGPLG 341
Query: 632 EQMGGRRGGRGGPG 645
E+ G RG G PG
Sbjct: 342 EK--GERGYPGTPG 353
Score = 61.2 bits (147), Expect = 3e-09
Identities = 117/434 (26%), Positives = 154/434 (35%), Gaps = 83/434 (19%)
Query: 278 PSSMGVYGQESGGFSGPGENRS---MSGPDN-----RGRGRGGF-DRGGMSRGGRGGGRG 328
P G GQ F GP ++ +SGP + + +G F +G + G G +G
Sbjct: 211 PGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQG 270
Query: 329 GMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQ 388
G GE+G KPG G D D G P + + G A
Sbjct: 271 MPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGP 330
Query: 389 CGVVKMNKRTGQPMIHIYLDKETGKPKGD-------ATVSYEDPP----TAKAAVEWFDG 437
G+V G+ Y T P+G+ PP +A F G
Sbjct: 331 PGIVIGTGPLGEKGERGY--PGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPG 388
Query: 438 KDFQGSKLKVSLARKKPPMNSMRGGLPPREG-----------------RGMPPPLRGGPG 480
+ +G K P S R GLP G + PP +G PG
Sbjct: 389 E--RGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPG 446
Query: 481 GPGGPG--GPMGRMGGRG---------GDRGGFPPRGPRGSRGNP-----SGGGNVQHRA 524
PG PG G +G G +G G RG P+GP G G P G + R
Sbjct: 447 IPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRD 506
Query: 525 GDWQCP----------NPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPG 574
G P PG + + + + K K + P FP G GR G
Sbjct: 507 GVAGVPGPQGTPGLIGQPGAKGEPGEFYFDL-RLKGDKGD----PGFPGQPGMTGRAGSP 561
Query: 575 GMRGGRGGLMDRGGPGGM-FRGGRGGDRG-GFRGGRGMDRGGFGGGRRGGPG-GPPGPLM 631
G G G +G PG + +G RG G GF G RG G G PG GP GP+
Sbjct: 562 GRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRG------DTGPPGPPGYGPAGPIG 615
Query: 632 EQMGGRRGGRGGPG 645
++ G+ G GGPG
Sbjct: 616 DK--GQAGFPGGPG 627
Score = 58.9 bits (141), Expect = 1e-08
Identities = 70/206 (33%), Positives = 87/206 (42%), Gaps = 35/206 (16%)
Query: 462 GLPPREGRGMPPPLRG-----GPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNP 514
G+ ++G P L+G G GP GP GP G+ G G G G RGP G+ G P
Sbjct: 43 GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102
Query: 515 SGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK-PEGFLPPPFPPPGGDRGRGGP 573
G D PG CN K + P G PP P G+ G G
Sbjct: 103 GNPGLPGIPGQDGPPGPPGIPG--------CNGTKGERGPLG--PPGLPGFAGNPGPPGL 152
Query: 574 GGMRGGRGGLMDRGGPGGMFRGGRG-----GDRG--GFRGGRG-MDRGGFGGGRRGGPGG 625
GM+G G ++ PG + +G RG G G G G +G + GF G GP G
Sbjct: 153 PGMKGDPGEILGH-VPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTG--PPGPPG 209
Query: 626 PPGPLME--QMG----GRRGGRGGPG 645
PPGP E QMG G +G +G G
Sbjct: 210 PPGPPGEKGQMGLSFQGPKGDKGDQG 235
Score = 38.5 bits (88), Expect = 0.020
Identities = 91/356 (25%), Positives = 107/356 (30%), Gaps = 79/356 (22%)
Query: 278 PSSMGVYGQ--ESGGFSGPGENRSMSGPDNRGRGRGGF-----DRGGMSRGGRGGGRGGM 330
P G GQ E G PG P GRG GF D+G G G G
Sbjct: 1141 PGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSP 1200
Query: 331 GA----GERGGFNKPG-----------GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLND 375
G GE+G PG G EGP D GP P + GL
Sbjct: 1201 GIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLP- 1259
Query: 376 SVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWF 435
G+ + G P G P + P +
Sbjct: 1260 --------------GIDGVKGDKGNP----------GWPGAPGVPGPKGDPGFQGMPGIG 1295
Query: 436 DGKDFQGSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPG-----GPGGPGGP 488
GSK + P + +G GLP +G +G PG GP GP GP
Sbjct: 1296 GSPGITGSKGDMG----PPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGP 1351
Query: 489 MGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 548
+ G G G P G +G +G P G Q G P P
Sbjct: 1352 YDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQ-QGVTGLVGIPGP---------------- 1394
Query: 549 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF 604
P GF P G+ G GP G RG G G PG M G GF
Sbjct: 1395 --PGIPGF--DGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGF 1446
Score = 33.5 bits (75), Expect = 0.64
Identities = 86/350 (24%), Positives = 104/350 (29%), Gaps = 67/350 (19%)
Query: 194 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 253
P P + D+ S + G S G S G+Q G P P GS
Sbjct: 1168 PGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSP 1227
Query: 254 SQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES-GGFSGPGENRSMSGPDNRGRGRGG 312
A GQ P MG G G G N G +G
Sbjct: 1228 GHATEGPKGDRGPQGQPGL--PGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKG- 1284
Query: 313 FDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQG 372
D G G GG G G+ +G PG P +GP G + D +G
Sbjct: 1285 -DPGFQGMPGIGGSPGITGS--KGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKG 1341
Query: 373 LNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAV 432
L G P + + E G P E PP K
Sbjct: 1342 LPGP---------------------PGPPGPYDIIKGEPGLP------GPEGPPGLKGLQ 1374
Query: 433 EWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRG--GPGGPGGPGGPMG 490
K QG V + PP G+P +G P +G GP GP GP G G
Sbjct: 1375 GLPGPKGQQGVTGLVGIPG--PP------GIPGFDGA---PGQKGEMGPAGPTGPRGFPG 1423
Query: 491 RMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQH---------RAGDWQCPN 531
G P G GS G P G +V H D QCP+
Sbjct: 1424 PPG----------PDGLPGSMG-PPGTPSVDHGFLVTRHSQTIDDPQCPS 1462
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 79.7 bits (195), Expect = 8e-15
Identities = 88/281 (31%), Positives = 118/281 (41%), Gaps = 32/281 (11%)
Query: 3 STDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62
S YS S A + YT Q + Y+ T+ +Y PT SY+ T+ Y
Sbjct: 1590 SPSYSPTSPAYEPRSPGGYTPQ-SPSYSPTSPSYS---------PTSPSYSP--TSPNYS 1637
Query: 63 QTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYG--TGAYDTTTATVTTTQASYAA 120
T+ + S P+ TS Y+ PT+P +YS Y + +Y T+ + + T SY+
Sbjct: 1638 PTSPSYS-PTSPSYSPTSPSYS-PTSP-SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1694
Query: 121 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETS-QPQSSTGGYNQPSLGYGQSNYSYP 179
S P P+Y + +PT P PT S P S + PS NYS P
Sbjct: 1695 TSP-SYSPTSPSYSPTSPSYSPTSPS--YSPTSPSYSPTSPSYSPTSPSYSPTSPNYS-P 1750
Query: 180 QVPGSYPMQPVTAP--PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 237
P P P +P PSY PTS + T PTS + S S + PS SY S
Sbjct: 1751 TSPNYTPTSPSYSPTSPSYSPTSPNYT-PTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSP 1809
Query: 238 -YGQQPPT------SYPPQTGSYSQAPSQYSQQSSSYGQQS 271
Y Q PT SY P + SYS +Y+ S SY S
Sbjct: 1810 RYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSS 1850
Score = 68.6 bits (166), Expect = 2e-11
Identities = 92/333 (27%), Positives = 131/333 (39%), Gaps = 47/333 (14%)
Query: 9 YSQAAAQQGYSAYTAQPTQ-GYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYGQTAYA 67
YS + ++ + PT Y+ T+ +Y S PT SY+ T+ +Y T+ +
Sbjct: 1636 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY--SPTSPSYSP--TSPSYSPTSPS 1691
Query: 68 TSYGQP------PTVEGTSTGYTTPTAPQAYSQPVQGYG--TGAYDTTTATVTTTQASYA 119
S P P+ TS Y+ PT+P +YS Y + +Y T+ + + T +Y+
Sbjct: 1692 YSPTSPSYSPTSPSYSPTSPSYS-PTSP-SYSPTSPSYSPTSPSYSPTSPSYSPTSPNYS 1749
Query: 120 AQSAYGTQPAYPAYGQQPAATAPTRPQ-----DGNKPTETSQPQSSTGGYNQPSLGYGQS 174
S T P P+Y + +PT P PT S +S Y+ S Y S
Sbjct: 1750 PTSPNYT-PTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPS-YSPTSPSYSPS 1807
Query: 175 NYSY-PQVPGSYPMQPVTAP--PSYPPTS--YSSTQPTSYDQSS---------YSQQNTY 220
+ Y PQ P P P +P PSY PTS Y+ T P SY SS YS +
Sbjct: 1808 SPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSP-SYSPSSPEYTPTSPKYSPTSPK 1866
Query: 221 GQPSS--YGQQSSYGQQSSYGQQP------PTS--YPPQTGSYSQAPSQYSQQSSSYGQQ 270
P+S Y S ++ P PTS Y P + YS YS S Y
Sbjct: 1867 YSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPT 1926
Query: 271 SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGP 303
S Y S G+S S++ P
Sbjct: 1927 SPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSP 1959
Score = 65.9 bits (159), Expect = 1e-10
Identities = 82/284 (28%), Positives = 107/284 (37%), Gaps = 37/284 (13%)
Query: 47 PTDVSYTQAQTTATYGQTAYATSYGQPP-----------TVEGTSTGYTTPTAPQAYSQ- 94
P + Q T A YG + + G P G S GY+ +P S
Sbjct: 1515 PAMTPWNQGATPA-YGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPG 1573
Query: 95 ---PVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQ----- 146
P Y + + + T +Y +S G P P+Y + +PT P
Sbjct: 1574 SPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTS 1633
Query: 147 DGNKPTETSQPQSSTGGYNQPSLGYGQSNYSY-PQVPGSYPMQPVTAP--PSYPPT--SY 201
PT S +S Y+ S Y ++ SY P P P P +P PSY PT SY
Sbjct: 1634 PNYSPTSPSYSPTSPS-YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1692
Query: 202 SSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQS-SYGQQPPTSYPPQTGSYSQAPSQY 260
S T P SY +S S T PS SY S SY P SY P + SYS Y
Sbjct: 1693 SPTSP-SYSPTSPSYSPT--SPSYSPTSPSYSPTSPSYSPTSP-SYSPTSPSYSPTSPNY 1748
Query: 261 SQQSSSYGQQS-SFRQDHPSSMGVYGQESGGFSGPGENRSMSGP 303
S S +Y S S+ PS Y S ++ N S + P
Sbjct: 1749 SPTSPNYTPTSPSYSPTSPS----YSPTSPNYTPTSPNYSPTSP 1788
Score = 59.7 bits (143), Expect = 8e-09
Identities = 77/252 (30%), Positives = 96/252 (38%), Gaps = 40/252 (15%)
Query: 70 YGQPPTVEGTSTGYTTPT---APQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 126
+G P+ G + TP A AY G+G A + + AS A+ + G
Sbjct: 1503 FGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGM-TPGAAGFSPSAASDASGFSPGY 1561
Query: 127 QPAY---PAYGQQPAATAPTRPQDGN------KPTETSQPQSSTGGYNQPSLGYGQSNYS 177
PA+ P P ++P P G PT + S GGY
Sbjct: 1562 SPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYT------------ 1609
Query: 178 YPQVPGSYPMQPVTAP--PSYPPTS--YSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYG 233
PQ P P P +P PSY PTS YS T P SY +S S T PS SY
Sbjct: 1610 -PQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSP-SYSPTSPSYSPT--SPSYSPTSPSYS 1665
Query: 234 QQS-SYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQS-SFRQDHPSSMGVYGQESGGF 291
S SY P SY P + SYS YS S SY S S+ PS Y S +
Sbjct: 1666 PTSPSYSPTSP-SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS----YSPTSPSY 1720
Query: 292 SGPGENRSMSGP 303
S + S + P
Sbjct: 1721 SPTSPSYSPTSP 1732
>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
Length = 1690
Score = 77.8 bits (190), Expect = 3e-14
Identities = 122/441 (27%), Positives = 154/441 (34%), Gaps = 66/441 (14%)
Query: 221 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 280
GQP G S G GQ P PP P P
Sbjct: 837 GQPGLPGYPGSPGAPGGKGQ-PGDVGPPGPAGMKGLPGL------------------PGR 877
Query: 281 MGVYGQES-GGFSGPGENRSMSGPDN-RG-RGRGGFDRGGMSRGGRGGGRGGMGA----G 333
G +G G GP + + GP +G RG GF G G+ G G GA G
Sbjct: 878 PGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFP-GFPGERGKPGAEGCPGAKGEPG 936
Query: 334 ERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVK 393
E+G PG G +GPP D E + S G D G
Sbjct: 937 EKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPG 996
Query: 394 MNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 451
M R G+P + G+P KG P + F G +
Sbjct: 997 MQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSP 1056
Query: 452 KKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRG 509
P + + G P+ +G P G PG G PG P G G G G++G +GPRG
Sbjct: 1057 GPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSP-GCPGHFGASGEQGLPGIQGPRG 1115
Query: 510 SRGNPSGGGNVQHRAGDWQCPN----PGCGNQNFAWRTECNQCKAPKPEGFL-------P 558
S G P G+ +G CP PG R + + P P G P
Sbjct: 1116 SPGRPGPPGS----SGPPGCPGDHGMPGL-------RGQPGEMGDPGPRGLQGDPGIPGP 1164
Query: 559 PPFPPPGGDRGRGGPGGMRGGRG-----GLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRG 613
P P G G G G++G +G GL D G PG + G G+RG G G+
Sbjct: 1165 PGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGD-PGSPGISPP 1223
Query: 614 GFGGGRRGGPG-----GPPGP 629
G G++G PG GPPGP
Sbjct: 1224 G-PRGKKGPPGPPGSSGPPGP 1243
Score = 71.2 bits (173), Expect = 3e-12
Identities = 67/197 (34%), Positives = 77/197 (39%), Gaps = 30/197 (15%)
Query: 462 GLPPREGRGMPPPLRGGPGGPG-------------GPGGPMGRMGGRGGDRGGFPPRGPR 508
G P GR +G PG PG GP GP G+ G G GFP GP
Sbjct: 581 GQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFP--GPP 638
Query: 509 GSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDR 568
G RG+P G+ R D G Q + + C P PP F P G +
Sbjct: 639 GERGHPGVPGHPGVRGPD------GLKGQ----KGDTISCNVTYPGRHGPPGFDGPPGPK 688
Query: 569 GRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG 628
G GP G G G +G PG G GFRG G GFGG + P GPPG
Sbjct: 689 GFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGP-PGFRGDMG--DPGFGGEKGSSPVGPPG 745
Query: 629 PLMEQMGGRRGGRGGPG 645
P G G +G PG
Sbjct: 746 P--PGSPGVNGQKGIPG 760
Score = 71.2 bits (173), Expect = 3e-12
Identities = 119/473 (25%), Positives = 156/473 (32%), Gaps = 76/473 (16%)
Query: 210 DQSSYSQQNTYGQPSSYGQQSSY-GQQSSYGQQPPTSYPPQTGS--------YSQAPSQY 260
D+ + Q G+P YG + G+ GQ P P GS + P
Sbjct: 991 DKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQ 1050
Query: 261 SQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR 320
+ S S G G + F PG P G ++G
Sbjct: 1051 GEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQG---L 1107
Query: 321 GGRGGGRGGMGA-GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 379
G G RG G G G PG P D G G P E D +QG + +
Sbjct: 1108 PGIQGPRGSPGRPGPPGSSGPPGCPGDHGMP---GLRGQPGEMGDPGPRGLQG-DPGIP- 1162
Query: 380 DDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD 439
G + +G P ++ + K A+ ++ P + G+
Sbjct: 1163 ----------GPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGER 1212
Query: 440 FQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRM------G 493
+S PP PR +G P P G GP GP G GR
Sbjct: 1213 GDPGSPGIS-----PP--------GPRGKKGPPGP--PGSSGPPGPAGATGRAPKDIPDP 1257
Query: 494 GRGGDRGGFPPRGPRGSRGNPSGGGNV---QHRAGDWQCPN----------------PGC 534
G GD+G P GPRG+ G P G+V + GD P PGC
Sbjct: 1258 GPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGC 1317
Query: 535 GNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFR 594
++ + P P+G P FP P G++G GP G +G G RG PG
Sbjct: 1318 DGKD----GQKGPVGFPGPQG--PHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPAD 1371
Query: 595 GGRGGDRGGFRGGRGM--DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 645
G G GM G G GP GP + GRRG G PG
Sbjct: 1372 VDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPG 1424
Score = 67.4 bits (163), Expect = 4e-11
Identities = 111/377 (29%), Positives = 135/377 (35%), Gaps = 90/377 (23%)
Query: 290 GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG----AGERGG--FNKPGG 343
GF GP +SG D +GR G G G G RG MG GE+G PG
Sbjct: 689 GFPGPQGAPGLSGSDGH-KGRPGTP-GTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGP 746
Query: 344 PMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMI 403
P G + G P DP F G +G P I
Sbjct: 747 PGSPGVNGQKGIPGDPA-------------------------FGHLGPPGKRGLSGVPGI 781
Query: 404 HIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR----KKPPMNSM 459
P+GD + P A + F G +G K + A PP +S
Sbjct: 782 K--------GPRGDPGCPGAEGP---AGIPGFLG--LKGPKGREGHAGFPGVPGPPGHSC 828
Query: 460 RGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRG--GFPPRGPRGSRGNPS 515
G P G+ P G PG PGG G P G +G G G +G G P G G+ G P
Sbjct: 829 ERGAPGIPGQPGLPGYPGSPGAPGGKGQP-GDVGPPGPAGMKGLPGLP--GRPGAHG-PP 884
Query: 516 GGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK-PEGFLPPPFPPPGGDRGRGGPG 574
G + GD P P PK P G P FP G+RG+ G
Sbjct: 885 GLPGIPGPFGDDGLPGP----------------PGPKGPRGL--PGFPGFPGERGKPGAE 926
Query: 575 GMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGM-----DRGGFG-GGRRGGPGGPPG 628
G G +G PG G GDR G RG +G D G ++G PG P
Sbjct: 927 GCPGA------KGEPGEKGMSGLPGDR-GLRGAKGAIGPPGDEGEMAIISQKGTPGEPGP 979
Query: 629 PLMEQMGGRRGGRGGPG 645
P + G RG +G PG
Sbjct: 980 PGDDGFPGERGDKGTPG 996
Score = 65.9 bits (159), Expect = 1e-10
Identities = 76/220 (34%), Positives = 89/220 (40%), Gaps = 35/220 (15%)
Query: 454 PPMNSMRG--GLPPREGRGMPPPLRGGPG--------GPGGPGGPMGRMGGRG--GDRGG 501
P M+G GLP R G PP L G PG GP GP GP G G G G+RG
Sbjct: 863 PGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGK 922
Query: 502 FPPRGPRGSRGNP-----SGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGF 556
G G++G P SG + G P A ++ P P G
Sbjct: 923 PGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPG- 981
Query: 557 LPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRG-----GRGGDRG--GFRGGRG 609
FP GD+G G G RG G R GP G RG G+ G G G G G
Sbjct: 982 -DDGFPGERGDKGTPGMQGRRGEPG----RYGPPGFHRGEPGEKGQPGPPGPPGPPGSTG 1036
Query: 610 MDRG--GFGG--GRRGGPGGPPGPLMEQMGGRRGGRGGPG 645
+ RG GF G G +G PG P P + G RG +G G
Sbjct: 1037 L-RGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKG 1075
Score = 63.5 bits (153), Expect = 6e-10
Identities = 70/212 (33%), Positives = 85/212 (40%), Gaps = 51/212 (24%)
Query: 463 LPPREGRGMP-PPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGN 519
+P + RG P PP GP GP G GP+G G +G GDRG P G G +G+ G
Sbjct: 58 VPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRG---PPGAAGDKGDKGPTGV 114
Query: 520 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGG 579
D +PG P P G P G G G G GG
Sbjct: 115 PGFPGLDGIPGHPG----------------PPGPRG-----KPGMSGHNGSRGDPGFPGG 153
Query: 580 RGGLMDRGGPGG-MFRGGRGGDRG----------GFRGGRGMD-----RGGFGGGRRGGP 623
RG L GPGG + G G++G G +G RG G +G G GP
Sbjct: 154 RGAL----GPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGP 209
Query: 624 GGPPGP--LMEQMG--GRRGGRGGPGKMDKGE 651
G PG L+ G GR G +G PG KG+
Sbjct: 210 TGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQ 241
Score = 61.6 bits (148), Expect = 2e-09
Identities = 147/549 (26%), Positives = 178/549 (32%), Gaps = 117/549 (21%)
Query: 175 NYSYPQVPGSY--PMQPVTAPPSYP--PTSYSSTQPTSYDQSSYSQQNTYGQPSSY--GQ 228
N +P PG P P+ PP P P Y T D G+P G
Sbjct: 348 NRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETG----DVGPPGPPGLLGRPGEACAGM 403
Query: 229 QSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES 288
G Q G G AP + + S + Q P S +Y S
Sbjct: 404 IGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYC--S 461
Query: 289 GGFSGPGENRSMSGPDNRGRGRGGFDR---------------GGMSRGGRGGGRGGMGA- 332
G GP + GP GRG G G GR G +G +G
Sbjct: 462 VGNPGPQGIKGKVGPPG-GRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLP 520
Query: 333 GERGGFNKPGGPMDEGPDL------DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFF 386
G G PG P EGP GPP + D V+G D F
Sbjct: 521 GWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFP 580
Query: 387 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 446
Q G + G+ K P GD +ED GK F G
Sbjct: 581 GQPGSHGRDGHAGE--------KGDPGPPGD----HEDATPG--------GKGFPGPL-- 618
Query: 447 VSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMG----------- 493
PP + G PP G PP RG PG PG PG GP G G
Sbjct: 619 ------GPPGKAGPVG-PPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVT 671
Query: 494 --GRGGDRGGFPPRGPRG---SRGNPSGGGNVQHRA-----GDWQCPNP-----GCGNQN 538
GR G G P GP+G +G P G+ H+ G + P P G+
Sbjct: 672 YPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPG 731
Query: 539 FAWRTECNQCKAPKPEGF--------LP--PPFPP--PGGDRGRGGPGGMRGGRGGLMDR 586
F + P P G +P P F P G RG G G++G RG D
Sbjct: 732 FGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRG---DP 788
Query: 587 GGPGGMFRGGRGGDRGGFRGGRGMD-RGGFGGG--------RRGGPGGPPGPLMEQMGGR 637
G PG G G G +G +G + GF G RG PG P P + G
Sbjct: 789 GCPGAEGPAGIPGFLG-LKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGS 847
Query: 638 RGGRGGPGK 646
G GG G+
Sbjct: 848 PGAPGGKGQ 856
Score = 57.8 bits (138), Expect = 3e-08
Identities = 116/441 (26%), Positives = 153/441 (34%), Gaps = 93/441 (21%)
Query: 290 GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGG--------------GRGGMGA--G 333
G SG R GP +G D+G G G G+ GM G
Sbjct: 86 GLSGEKGMRGDRGPPGAAGDKG--DKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNG 143
Query: 334 ERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIY-----VQGLNDSVTLDDLADFFKQ 388
RG PGG GP LG P + E ++ I +QG L L +
Sbjct: 144 SRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGA 203
Query: 389 CGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYE----DP--------PTAKAAVEW 434
G G+P + + + G+P KG+ V + DP P VE
Sbjct: 204 GGPAGPTGYPGEPGL-VGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEP 262
Query: 435 FDGKDFQGSK----LKVSLARKKPPMNSMRGGLPPREGRGMP--PPLRGGPGGPGGPGGP 488
D ++G K + + PP G+ + +G+P P RG PG G PG P
Sbjct: 263 PDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFP 322
Query: 489 --MGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR-T 543
G +G G G G P+G G+RG+P G + + P G+ F R
Sbjct: 323 GLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPP---GDPGFPGRYG 379
Query: 544 ECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRG-----GRGGLMDR--------GGPG 590
E P P G L P G G GP G G G G+ R G PG
Sbjct: 380 ETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPG 439
Query: 591 GMFRGGRGGDRG-----------------GFRGGRGMDRGGFGGGRRG---------GPG 624
G G +G G +G G G G +G GP
Sbjct: 440 SPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPM 499
Query: 625 GPPGPLMEQMGGRRGGRGGPG 645
GPPGP + GR+G +G G
Sbjct: 500 GPPGP--PGLPGRQGSKGDLG 518
Score = 57.0 bits (136), Expect = 5e-08
Identities = 117/480 (24%), Positives = 144/480 (30%), Gaps = 96/480 (20%)
Query: 217 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD 276
Q G P G S+G G PT YP + G GQ
Sbjct: 186 QGDRGDPGLPGLPGSWGAGGPAG---PTGYPGEPGLVGPP-----------GQPGRPGLK 231
Query: 277 HPSSMGVYGQ-----ESGGFSGPGENRSMSGPD----NRGRGRGGFDRGGMSRGGRGGGR 327
+GV GQ E G PG + PD +G G G + G G +
Sbjct: 232 GNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIP-GMVGLPGPPGRK 290
Query: 328 GGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK 387
G G G +G PG P G G P P + + GL +
Sbjct: 291 GESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPK------- 343
Query: 388 QCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV 447
G G P + + P GD T G G +
Sbjct: 344 --GDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPG--LLGRPGEA 399
Query: 448 SLARKKPPMNSMRGGLPPREGR----GMPPPLRGGPGGPGGPG----------------- 486
PP GLP G G P G PG PG PG
Sbjct: 400 CAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIY 459
Query: 487 ------GPMGRMGGRGGDRGGFPPRGPRGSRG------------NPSGGGNVQHRAGDWQ 528
GP G + G+ G GG P+G +G+ G P G Q GD
Sbjct: 460 CSVGNPGPQG-IKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLG 518
Query: 529 CPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGG 588
P W P EG PP P G G GP G +G +G ++
Sbjct: 519 LPG---------WLGTKGDPGPPGAEG--PPGLP---GKHGASGPPGNKGAKGDMVVSRV 564
Query: 589 PGGMFRGGRGGDRG-GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKM 647
G +G RG D GF G G G G G PGP + GG+G PG +
Sbjct: 565 KG--HKGERGPDGPPGFPG----QPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPL 618
Score = 56.2 bits (134), Expect = 9e-08
Identities = 121/433 (27%), Positives = 146/433 (33%), Gaps = 95/433 (21%)
Query: 278 PSSMGVYGQE------SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 331
P S GV GQ+ + G GP R +SG RG D G G G G +G
Sbjct: 747 PGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRG--DPGCPGAEGPAGIPGFLG 804
Query: 332 A----GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK 387
G G PG P G + G P P + G
Sbjct: 805 LKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPG 864
Query: 388 QCGVVKMNKRTGQPMIH--IYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKL 445
G+ + G+P H L G P GD + P + F G F G +
Sbjct: 865 PAGMKGLPGLPGRPGAHGPPGLPGIPG-PFGDDGLPGPPGPKGPRGLPGFPG--FPGERG 921
Query: 446 KVSL----ARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG-----------GPMG 490
K K P GLP G LRG G G PG G G
Sbjct: 922 KPGAEGCPGAKGEPGEKGMSGLPGDRG------LRGAKGAIGPPGDEGEMAIISQKGTPG 975
Query: 491 RMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 550
G G D GFP G RG +G P +Q R G+ PG R E +
Sbjct: 976 EPGPPGDD--GFP--GERGDKGTPG----MQGRRGE-----PGRYGPPGFHRGEPGEKGQ 1022
Query: 551 PKPEGFLPPP----------FPPPGGDRGR-GGPG-----GMRGGRGGLMDRGGPGGMF- 593
P P G PP FP GD+G G PG G+ G RG ++G P F
Sbjct: 1023 PGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFG 1082
Query: 594 ---------------RGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG--GPPGPLMEQM 634
G G++G G +G RG GR G PG GPPG +
Sbjct: 1083 PPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSP------GRPGPPGSSGPPGCPGDH- 1135
Query: 635 GGRRGGRGGPGKM 647
G G RG PG+M
Sbjct: 1136 -GMPGLRGQPGEM 1147
Score = 53.5 bits (127), Expect = 6e-07
Identities = 67/210 (31%), Positives = 79/210 (37%), Gaps = 43/210 (20%)
Query: 472 PPPLRGGPGGPGGPG--------GPMGRMG--GRGGD--RGGFPPRGPRGSRGNPSGGGN 519
P PL+G PG PG PG GP G G GR G+ G P GP+G G P G
Sbjct: 362 PLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGE 421
Query: 520 VQHRAGDWQCPN----------PGCGNQNFAWRTECNQCKA--PKPEGFLPPPFPPPG-G 566
P PG + C P P+G PP G G
Sbjct: 422 AGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRG 481
Query: 567 DRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG 624
+G G G+ G M GP G+ GR G +G G G G G G PG
Sbjct: 482 PKGEKGNEGLCACEPGPMGPPGPPGL--PGRQGSKGDLGLPGWLGTK------GDPGPPG 533
Query: 625 --GPPGPLMEQMGGRRGGRGGPG-KMDKGE 651
GPPG + G+ G G PG K KG+
Sbjct: 534 AEGPPG-----LPGKHGASGPPGNKGAKGD 558
Score = 51.2 bits (121), Expect = 3e-06
Identities = 109/397 (27%), Positives = 132/397 (33%), Gaps = 87/397 (21%)
Query: 216 QQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQ 275
Q G P G Q G G + P+ P G + Q + G
Sbjct: 1143 QPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHG-----LKGQKGTKGASGLHDV 1197
Query: 276 DHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGER 335
P +G+ G + G G + +S P RG+ +G G G G GA R
Sbjct: 1198 GPPGPVGIPGLK--GERGDPGSPGISPPGPRGK------KGPPGPPGSSGPPGPAGATGR 1249
Query: 336 GGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMN 395
+ P D GP D GPP D A GL SV L L CG+
Sbjct: 1250 APKDIP----DPGPPGDQGPP---GPDGPRGAPGPPGLPGSVDL--LRGEPGDCGL---- 1296
Query: 396 KRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPP 455
G P G P Y+ P DGKD G K V + P
Sbjct: 1297 --PGPP----------GPPGPPGPPGYKGFPGC-------DGKD--GQKGPVGFPGPQGP 1335
Query: 456 MNSMRGGLPPREGRGMP-PPLRGGPGGPGGPGGPMG---------RMGGRGGDRGGFPPR 505
+ G PP E +G+P PP R GP G GP G G R+ G G G R
Sbjct: 1336 -HGFPG--PPGE-KGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPG---MR 1388
Query: 506 GPRGSRGNPSGGGNVQHRAGDWQCPNPGC-GNQNFAWRTECNQCKAPKPEGFLPPPFPPP 564
GP G+ G P G PGC G R + P P P
Sbjct: 1389 GPEGAMGLPGMRGP----------SGPGCKGEPGLDGRRGVDGV----------PGSPGP 1428
Query: 565 GGDRGRGGPGGMRGGRG--GLMDRGGPGGMFRGGRGG 599
G +G G G GG G G + GP G G GG
Sbjct: 1429 PGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLGG 1465
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.134 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,569,942
Number of Sequences: 37866
Number of extensions: 3068017
Number of successful extensions: 56030
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 591
Number of HSP's successfully gapped in prelim test: 1351
Number of HSP's that attempted gapping in prelim test: 14315
Number of HSP's gapped (non-prelim): 15075
length of query: 661
length of database: 18,247,518
effective HSP length: 109
effective length of query: 552
effective length of database: 14,120,124
effective search space: 7794308448
effective search space used: 7794308448
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.