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Search of human proteins with 24797067
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24797067 major histocompatibility complex, class I, A
precursor [Homo sapiens]
(365 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24797067 major histocompatibility complex, class I, A precurs... 751 0.0
gi|17986001 major histocompatibility complex, class I, B precurs... 640 0.0
gi|52630342 major histocompatibility complex, class I, C precurs... 610 e-175
gi|4504415 major histocompatibility complex, class I, G precurso... 594 e-170
gi|62912479 major histocompatibility complex, class I, E precurs... 583 e-167
gi|149158702 major histocompatibility complex, class I, F isofor... 578 e-165
gi|149158698 major histocompatibility complex, class I, F isofor... 577 e-165
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 498 e-141
gi|149158700 major histocompatibility complex, class I, F isofor... 310 1e-84
gi|4504417 major histocompatibility complex, class I-related [Ho... 235 5e-62
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 216 2e-56
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 199 2e-51
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 199 4e-51
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 197 9e-51
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 163 3e-40
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 145 6e-35
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 142 4e-34
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 142 6e-34
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 139 5e-33
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 139 5e-33
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 108 1e-23
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 108 1e-23
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 100 3e-21
gi|110618224 CD1A antigen precursor [Homo sapiens] 92 7e-19
gi|169168591 PREDICTED: similar to major histocompatibility comp... 74 3e-13
gi|239740920 PREDICTED: similar to major histocompatibility comp... 72 6e-13
gi|239740918 PREDICTED: similar to major histocompatibility comp... 72 6e-13
gi|24797076 major histocompatibility complex, class II, DP beta ... 72 1e-12
gi|239758095 PREDICTED: similar to major histocompatibility comp... 72 1e-12
gi|239740749 PREDICTED: similar to major histocompatibility comp... 72 1e-12
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 751 bits (1939), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 1 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF 60
MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF
Sbjct: 1 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF 60
Query: 61 DSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQ 120
DSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQ
Sbjct: 61 DSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQ 120
Query: 121 IMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQL 180
IMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQL
Sbjct: 121 IMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQL 180
Query: 181 RAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLT 240
RAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLT
Sbjct: 181 RAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLT 240
Query: 241 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL 300
WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL
Sbjct: 241 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL 300
Query: 301 SSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSL 360
SSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSL
Sbjct: 301 SSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSL 360
Query: 361 TACKV 365
TACKV
Sbjct: 361 TACKV 365
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 640 bits (1650), Expect = 0.0
Identities = 310/362 (85%), Positives = 329/362 (90%)
Query: 1 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF 60
M VMAPRT+LLLLS ALALT+TWAGSHSMRYF+TSVSRPGRGEPRFI+VGYVDDTQFVRF
Sbjct: 1 MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRF 60
Query: 61 DSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQ 120
DSDAAS R EPRAPWIEQEGPEYWD+ T+ KAQ+QTDR L LRGYYNQSEAGSHT+Q
Sbjct: 61 DSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQ 120
Query: 121 IMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQL 180
MYGCDVG DGR LRG+ Q AYDGKDYIALNEDLRSWTAAD AAQIT+RKWEAA EAEQ
Sbjct: 121 SMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR 180
Query: 181 RAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLT 240
RAYL+G CVEWLRRYLENGK+ L+R DPPKTH+THHPISDHEATLRCWALGFYPAEITLT
Sbjct: 181 RAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLT 240
Query: 241 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL 300
WQRDGEDQTQDTELVETRPAGD TFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWE
Sbjct: 241 WQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 300
Query: 301 SSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSL 360
SSQ T+PIVGI+AGL +L V+ GAVVAAVM RRKSS KGGSY+QAA SDSAQGSDVSL
Sbjct: 301 SSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVSL 360
Query: 361 TA 362
TA
Sbjct: 361 TA 362
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 610 bits (1573), Expect = e-175
Identities = 298/365 (81%), Positives = 322/365 (88%), Gaps = 1/365 (0%)
Query: 1 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF 60
M VMAPR LLLLLSG LALT+TWA SHSMRYF T+VSRPGRGEPRFI+VGYVDDTQFVRF
Sbjct: 1 MRVMAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRF 60
Query: 61 DSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQ 120
DSDAAS R EPRAPW+EQEGPEYWD+ET+ K Q+Q DRV L LRGYYNQSE GSHT+Q
Sbjct: 61 DSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQ 120
Query: 121 IMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQL 180
M GCD+G DGR LRGY Q AYDGKDYIALNEDLRSWTAAD AAQIT+RK EAA AEQL
Sbjct: 121 RMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQL 180
Query: 181 RAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLT 240
RAYL+GTCVEWLRRYLENGKETLQR +PPKTH+THHP+SDHEATLRCWALGFYPAEITLT
Sbjct: 181 RAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLT 240
Query: 241 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL 300
WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSG+EQRYTCH+QHEGL +PLTL WE
Sbjct: 241 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEP 300
Query: 301 SSQPTIPIVGIIAGL-VLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVS 359
SSQPTIPI+GI+AGL VL+ + GAVV A+M RRKSS KGGS +QAA S+SAQGSD S
Sbjct: 301 SSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGSDES 360
Query: 360 LTACK 364
L CK
Sbjct: 361 LITCK 365
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 594 bits (1532), Expect = e-170
Identities = 280/338 (82%), Positives = 307/338 (90%)
Query: 1 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF 60
M VMAPRTL LLLSGAL LT+TWAGSHSMRYF +VSRPGRGEPRFIA+GYVDDTQFVRF
Sbjct: 1 MVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRF 60
Query: 61 DSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQ 120
DSD+A RMEPRAPW+EQEGPEYW++ETRN KA +QTDR++L TLRGYYNQSEA SHT+Q
Sbjct: 61 DSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQ 120
Query: 121 IMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQL 180
M GCD+GSDGR LRGY Q AYDGKDY+ALNEDLRSWTAAD AAQI+KRK EAA+ AEQ
Sbjct: 121 WMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQR 180
Query: 181 RAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLT 240
RAYL+GTCVEWL RYLENGKE LQR DPPKTH+THHP+ D+EATLRCWALGFYPAEI LT
Sbjct: 181 RAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILT 240
Query: 241 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL 300
WQRDGEDQTQD ELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLP+PL LRW+
Sbjct: 241 WQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQ 300
Query: 301 SSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSD 338
SS PTIPI+GI+AGLV+L AV+TGA VAAV+WR+KSSD
Sbjct: 301 SSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD 338
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 583 bits (1504), Expect = e-167
Identities = 279/354 (78%), Positives = 314/354 (88%)
Query: 4 MAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSD 63
M TLLLLLS ALALTQTWAGSHS++YF TSVSRPGRGEPRFI+VGYVDDTQFVRFD+D
Sbjct: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
Query: 64 AASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMY 123
AAS RM PRAPW+EQEG EYWD+ETR+ + +Q RV+L TLRGYYNQSEAGSHT+Q M+
Sbjct: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
Query: 124 GCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLRAY 183
GC++G DGRFLRGY Q AYDGKDY+ LNEDLRSWTA D AAQI+++K A EAE RAY
Sbjct: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
Query: 184 LDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQR 243
L+ TCVEWL +YLE GKETL +PPKTH+THHPISDHEATLRCWALGFYPAEITLTWQ+
Sbjct: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
Query: 244 DGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQ 303
DGE TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLP+P+TLRW+ +SQ
Sbjct: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
Query: 304 PTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSD 357
PTIPIVGIIAGLVLLG+V++GAVVAAV+WR+KSS KGGSY++A SDSAQGS+
Sbjct: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSE 354
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 578 bits (1491), Expect = e-165
Identities = 278/353 (78%), Positives = 305/353 (86%)
Query: 4 MAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSD 63
MAPR+LLLLLSGALALT TWAGSHS+RYF T+VSRPGRGEPR+IAV YVDDTQF+RFDSD
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 64 AASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMY 123
AA RMEPR PW+EQEGP+YW+ T KA +QTDRV L L YNQSEAGSHT+Q M
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 124 GCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLRAY 183
GCD+G DGR LRGY Q AYDGKDYI+LNEDLRSWTAAD AQIT+R +EA AE+ R Y
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 184 LDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQR 243
L+G C+E LRRYLENGKETLQR DPPK H+ HHPISDHEATLRCWALGFYPAEITLTWQR
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 244 DGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQ 303
DGE+QTQDTELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+PL LRWE S Q
Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
Query: 304 PTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGS 356
PTIPIVGI+AGLV+LGAV+TGAVVAAVMWR+KSSDR GSY+QAA+ G+
Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAAYSVVSGN 353
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 577 bits (1487), Expect = e-165
Identities = 277/345 (80%), Positives = 302/345 (87%)
Query: 4 MAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSD 63
MAPR+LLLLLSGALALT TWAGSHS+RYF T+VSRPGRGEPR+IAV YVDDTQF+RFDSD
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 64 AASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMY 123
AA RMEPR PW+EQEGP+YW+ T KA +QTDRV L L YNQSEAGSHT+Q M
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 124 GCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLRAY 183
GCD+G DGR LRGY Q AYDGKDYI+LNEDLRSWTAAD AQIT+R +EA AE+ R Y
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 184 LDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQR 243
L+G C+E LRRYLENGKETLQR DPPK H+ HHPISDHEATLRCWALGFYPAEITLTWQR
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 244 DGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQ 303
DGE+QTQDTELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+PL LRWE S Q
Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
Query: 304 PTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAA 348
PTIPIVGI+AGLV+LGAV+TGAVVAAVMWR+KSSDR GSY+QAA
Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 345
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 498 bits (1282), Expect = e-141
Identities = 239/317 (75%), Positives = 270/317 (85%), Gaps = 4/317 (1%)
Query: 25 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYW 84
GSHS+RYF+T+VSRPG GEPRFI+VGYVDDTQFVRFDSD+A+ R EPRAPW+EQEGPEYW
Sbjct: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
Query: 85 DQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYGCDVGSDGRFLRGYRQDAYDG 144
D++TR VK +Q+ RV L TLRGYYNQSEAGSHT+Q+MYGCDVG DGRFLRG+ QDAYDG
Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
Query: 145 KDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLRAYLDGTCVEWLRRYLENGKETLQ 204
+DYIALNEDLRSWTAAD AAQITKRK EAA AE+ R YL+G CVE LRRYLE GK+ L
Sbjct: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217
Query: 205 RTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGT 264
R DPPK H+THHPIS+ E TLRCWALGFYP EI+LTWQR+GEDQTQD ELVETRP+GDGT
Sbjct: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277
Query: 265 FQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITG 324
FQKWAA+VVPSGEEQRYTC VQHEGL +PLTLRWE Q + I+GII GLVLL +
Sbjct: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWE-PPQTSFLIMGIIVGLVLL---VVA 333
Query: 325 AVVAAVMWRRKSSDRKG 341
V AV+WR+K S R+G
Sbjct: 334 LVAGAVIWRKKRSGREG 350
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 310 bits (794), Expect = 1e-84
Identities = 151/204 (74%), Positives = 169/204 (82%)
Query: 4 MAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSD 63
MAPR+LLLLLSGALALT TWAGSHS+RYF T+VSRPGRGEPR+IAV YVDDTQF+RFDSD
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 64 AASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMY 123
AA RMEPR PW+EQEGP+YW+ T KA +QTDRV L L YNQSEAGSHT+Q M
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 124 GCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLRAY 183
GCD+G DGR LRGY Q AYDGKDYI+LNEDLRSWTAAD AQIT+R +EA AE+ R Y
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 184 LDGTCVEWLRRYLENGKETLQRTD 207
L+G C+E LRRYLENGKETLQR +
Sbjct: 181 LEGECLELLRRYLENGKETLQRAE 204
Score = 84.7 bits (208), Expect = 1e-16
Identities = 42/52 (80%), Positives = 47/52 (90%)
Query: 297 RWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAA 348
R E S QPTIPIVGI+AGLV+LGAV+TGAVVAAVMWR+KSSDR GSY+QAA
Sbjct: 202 RAEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 253
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 235 bits (599), Expect = 5e-62
Identities = 131/347 (37%), Positives = 200/347 (57%), Gaps = 19/347 (5%)
Query: 1 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF 60
MA + P ++L++ + + T HS+RYF VS P G P FI+VGYVD +
Sbjct: 5 MAFLLPLIIVLMVKHSDSRT------HSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTY 58
Query: 61 DSDAASQRMEPRAPWI-EQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTI 119
DS +++ EPRAPW+ E P++W++ T+ ++ Q +V+L L+ +YN S GSHT
Sbjct: 59 DS--VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTY 114
Query: 120 QIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEA-AHEAE 178
Q M GC++ DG G+ Q AYDG+D++ N+D SW A D A K+ WEA HE
Sbjct: 115 QRMIGCELLEDGS-TTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELL 173
Query: 179 QLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEIT 238
+ +L+ C+ WL+R+LE GK+TLQRT+PP + L C A GFYP EI
Sbjct: 174 YQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIY 233
Query: 239 LTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 298
+TW ++GE+ Q+ + + P+GDGT+Q WA++ + Y+CHV+H G+ L +
Sbjct: 234 MTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQ 293
Query: 299 ELSSQPTIPIV-GIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSY 344
E TIP+V ++G ++L V+ G V ++WRR+ ++ G Y
Sbjct: 294 E---SETIPLVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIY 335
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 216 bits (551), Expect = 2e-56
Identities = 125/345 (36%), Positives = 187/345 (54%), Gaps = 9/345 (2%)
Query: 6 PRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAA 65
P LLL+L L SHS+ Y F S G F A+GYVDD FV +D +
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
Query: 66 SQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYG 124
S+R+EPR PW+ + W Q ++++K VD T+ +N S+ SHT+Q++ G
Sbjct: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
Query: 125 CDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH-EAEQLRAY 183
C++ D GY + YDG+D++ D W AA+ A TK +WE A Q RAY
Sbjct: 124 CEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
Query: 184 LDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQR 243
L+ C L++ LE G+ L + PP +THH ++ TLRC AL +YP IT+ W +
Sbjct: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLK 241
Query: 244 DGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSS 302
D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +PL + WE S
Sbjct: 242 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 301
Query: 303 QPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQA 347
T+ ++G+I+G+ + ++ ++ ++ +R+ S G Y A
Sbjct: 302 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLA 345
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 199 bits (507), Expect = 2e-51
Identities = 111/306 (36%), Positives = 172/306 (56%), Gaps = 9/306 (2%)
Query: 45 RFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLG 103
R + +GYVDD FV +D + S+R+EPR PW+ + W Q ++++K VD
Sbjct: 23 RLLPLGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
Query: 104 TLRGYYNQSEAGSHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMA 163
T+ +N S+ SHT+Q++ GC++ D GY + YDG+D++ D W AA+
Sbjct: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
Query: 164 AQITKRKWEAAH-EAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHE 222
A TK +WE A Q RAYL+ C L++ LE G+ L + PP +THH ++
Sbjct: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
Query: 223 ATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRY 281
TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRY
Sbjct: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
Query: 282 TCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKG 341
TC V+H GL +PL + WE S T+ ++G+I+G+ + ++ ++ ++ +R+ S
Sbjct: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316
Query: 342 GSYTQA 347
G Y A
Sbjct: 317 GHYVLA 322
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 199 bits (505), Expect = 4e-51
Identities = 120/345 (34%), Positives = 179/345 (51%), Gaps = 23/345 (6%)
Query: 6 PRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAA 65
P LLL+L L SHS+ Y F S G F A+GYVDD FV +D +
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
Query: 66 SQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYG 124
S+R+EPR PW+ + W Q ++++K VD T+ +N S+ SHT+Q++ G
Sbjct: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
Query: 125 CDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH-EAEQLRAY 183
C++ D GY + YDG+D++ D W AA+ A TK +WE A Q RAY
Sbjct: 124 CEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
Query: 184 LDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQR 243
L+ C L++ LE G+ L + TLRC AL +YP IT+ W +
Sbjct: 183 LERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYPQNITMKWLK 227
Query: 244 DGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSS 302
D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +PL + WE S
Sbjct: 228 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 287
Query: 303 QPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQA 347
T+ ++G+I+G+ + ++ ++ ++ +R+ S G Y A
Sbjct: 288 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLA 331
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 197 bits (502), Expect = 9e-51
Identities = 117/307 (38%), Positives = 166/307 (54%), Gaps = 15/307 (4%)
Query: 1 MAVMAPRTL-LLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVR 59
M M P L LLLL G + G +S+ Y +T +S+ P F A+G ++D QF R
Sbjct: 1 MVRMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFR 60
Query: 60 FDSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTI 119
++S ++ +P W + EG E W Q+++ KA+ L + YYN S GSH +
Sbjct: 61 YNSK--DRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVL 117
Query: 120 QIMYGCDVG---SDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHE 176
Q +GC++ S G F + Y YDGKDYI N+++ +W D AAQITK+KWEA
Sbjct: 118 QGRFGCEIENNRSSGAFWKYY----YDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPV 173
Query: 177 -AEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPA 235
++ +AYL+ C LR+YL+ K L R DPP +T H + L+C A FYP
Sbjct: 174 YVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPG 233
Query: 236 EITLTWQRDGEDQTQDTEL-VETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPL 294
+I + W R GE Q+ EL + G+GT+Q W V VP + Y+CHVQH L +PL
Sbjct: 234 KIDVHWTRAGE--VQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPL 291
Query: 295 TLRWELS 301
+ WE S
Sbjct: 292 VVPWEAS 298
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 163 bits (412), Expect = 3e-40
Identities = 87/234 (37%), Positives = 133/234 (56%), Gaps = 5/234 (2%)
Query: 116 SHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH 175
SHT+Q++ GC++ D GY + YDG+D++ D W AA+ A TK +WE
Sbjct: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 176 -EAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYP 234
A Q RAYL+ C L++ LE G+ L + PP +THH ++ TLRC AL +YP
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
Query: 235 AEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKP 293
IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
Query: 294 LTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQA 347
L + WE S T+ ++G+I+G+ + ++ ++ ++ +R+ S G Y A
Sbjct: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLA 257
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 145 bits (366), Expect = 6e-35
Identities = 82/234 (35%), Positives = 125/234 (53%), Gaps = 19/234 (8%)
Query: 116 SHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH 175
SHT+Q++ GC++ D GY + YDG+D++ D W AA+ A TK +WE
Sbjct: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 176 -EAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYP 234
A Q RAYL+ C L++ LE G+ L + TLRC AL +YP
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYP 130
Query: 235 AEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKP 293
IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
Query: 294 LTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQA 347
L + WE S T+ ++G+I+G+ + ++ ++ ++ +R+ S G Y A
Sbjct: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLA 243
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 142 bits (359), Expect = 4e-34
Identities = 89/289 (30%), Positives = 149/289 (51%), Gaps = 16/289 (5%)
Query: 9 LLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQR 68
L L ++ A A HS+RY +S+ G + F+A G++D F+R+D +R
Sbjct: 8 LFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQ--KRR 65
Query: 69 MEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYGCDV 127
+P+ W E G + WD ET ++ Q DL + + G H++Q + C++
Sbjct: 66 AKPQGQWAENVLGAKTWDTETEDLTENGQ----DLRRTLTHIKDQKGGLHSLQEIRVCEI 121
Query: 128 GSDGRFLRGYRQDAYDGKDYIALNEDLRSWT------AADMAAQITKRKWEAAHEAEQLR 181
D RG R YDG+ +++ N + + T A +A +T E A + +
Sbjct: 122 HEDSS-TRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHY 180
Query: 182 AYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTW 241
+ C++ L+RYL++G ++RT PP ++T +S+ T+ C A FYP ITLTW
Sbjct: 181 RAMQADCLQKLQRYLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTW 239
Query: 242 QRDGEDQTQDT-ELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEG 289
++DG + +T + + P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 240 RQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 142 bits (357), Expect = 6e-34
Identities = 90/291 (30%), Positives = 150/291 (51%), Gaps = 18/291 (6%)
Query: 9 LLLLLSGALALTQTWAGS--HSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAAS 66
+ LLL+G A + HS+RY T +S G + F+ ++D F+R D
Sbjct: 6 VFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKC- 64
Query: 67 QRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYGC 125
R +P+ W E G + WD+ETR++ + R+ L ++ + G H++Q + C
Sbjct: 65 -RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK----DQKEGLHSLQEIRVC 119
Query: 126 DVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWT------AADMAAQITKRKWEAAHEAEQ 179
++ D R + YDG+ +++ N + + WT A +A + E A + +
Sbjct: 120 EIHEDNS-TRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKT 178
Query: 180 LRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITL 239
+ C++ LRRYL++G L+RT PP ++T S+ T+ C A GFYP ITL
Sbjct: 179 HYHAMHADCLQELRRYLKSGV-VLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITL 237
Query: 240 TWQRDGEDQTQDT-ELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEG 289
+W++DG + DT + + P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 238 SWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSG 288
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 139 bits (349), Expect = 5e-33
Identities = 99/332 (29%), Positives = 164/332 (49%), Gaps = 22/332 (6%)
Query: 9 LLLLLSGALALTQTWAGSH-SMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQ 67
LL LL G+L A SH S+ Y T+VS P G P F G++ Q++ ++S
Sbjct: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNS--LRG 66
Query: 68 RMEPRAPWI-EQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYGCD 126
EP W+ E + YW++ET +++ + + L G G +T+Q + GC+
Sbjct: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCE 120
Query: 127 VGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLR-AYLD 185
+G D + + A +G++++ + +W A ++W+ +A +L
Sbjct: 121 LGPDNTSVPTAKF-ALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLL 179
Query: 186 GTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDG 245
+C LR +LE G+ L+ +PP + P S + L C A FYP E+ L + R+G
Sbjct: 180 FSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG 239
Query: 246 EDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPT 305
T + P DG+F +++ V SG+E Y C VQH GL +PL + E ++ +
Sbjct: 240 --LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSS 297
Query: 306 IPIVGIIAGLVLLGAVITGAVVAAVMWRRKSS 337
+ +VGI+ G++LL A AV A++WRR S
Sbjct: 298 VLVVGIVIGVLLLTA---AAVGGALLWRRMRS 326
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 139 bits (349), Expect = 5e-33
Identities = 99/332 (29%), Positives = 164/332 (49%), Gaps = 22/332 (6%)
Query: 9 LLLLLSGALALTQTWAGSH-SMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQ 67
LL LL G+L A SH S+ Y T+VS P G P F G++ Q++ ++S
Sbjct: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNS--LRG 66
Query: 68 RMEPRAPWI-EQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYGCD 126
EP W+ E + YW++ET +++ + + L G G +T+Q + GC+
Sbjct: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCE 120
Query: 127 VGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLR-AYLD 185
+G D + + A +G++++ + +W A ++W+ +A +L
Sbjct: 121 LGPDNTSVPTAKF-ALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLL 179
Query: 186 GTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDG 245
+C LR +LE G+ L+ +PP + P S + L C A FYP E+ L + R+G
Sbjct: 180 FSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG 239
Query: 246 EDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPT 305
T + P DG+F +++ V SG+E Y C VQH GL +PL + E ++ +
Sbjct: 240 --LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSS 297
Query: 306 IPIVGIIAGLVLLGAVITGAVVAAVMWRRKSS 337
+ +VGI+ G++LL A AV A++WRR S
Sbjct: 298 VLVVGIVIGVLLLTA---AAVGGALLWRRMRS 326
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 108 bits (269), Expect = 1e-23
Identities = 53/141 (37%), Positives = 83/141 (58%), Gaps = 3/141 (2%)
Query: 208 PPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQ 266
PP +THH ++ TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q
Sbjct: 27 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
Query: 267 KWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAV 326
W + VP GEEQRYTC V+H GL +PL + WE S T+ ++G+I+G+ + ++ +
Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 144
Query: 327 VAAVMWRRKSSDRKGGSYTQA 347
+ ++ +R+ S G Y A
Sbjct: 145 LFIILRKRQGSRGAMGHYVLA 165
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 108 bits (269), Expect = 1e-23
Identities = 53/141 (37%), Positives = 83/141 (58%), Gaps = 3/141 (2%)
Query: 208 PPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQ 266
PP +THH ++ TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q
Sbjct: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
Query: 267 KWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAV 326
W + VP GEEQRYTC V+H GL +PL + WE S T+ ++G+I+G+ + ++ +
Sbjct: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232
Query: 327 VAAVMWRRKSSDRKGGSYTQA 347
+ ++ +R+ S G Y A
Sbjct: 233 LFIILRKRQGSRGAMGHYVLA 253
Score = 63.2 bits (152), Expect = 4e-10
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Query: 6 PRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAA 65
P LLL+L L SHS+ Y F S G F A+GYVDD FV +D +
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
Query: 66 SQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSE 113
S+R+EPR PW+ + W Q ++++K VD T+ +N S+
Sbjct: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 99.8 bits (247), Expect = 3e-21
Identities = 48/125 (38%), Positives = 75/125 (60%), Gaps = 2/125 (1%)
Query: 224 TLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYT 282
TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYT
Sbjct: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
Query: 283 CHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGG 342
C V+H GL +PL + WE S T+ ++G+I+G+ + ++ ++ ++ +R+ S G
Sbjct: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234
Query: 343 SYTQA 347
Y A
Sbjct: 235 HYVLA 239
Score = 63.2 bits (152), Expect = 4e-10
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Query: 6 PRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAA 65
P LLL+L L SHS+ Y F S G F A+GYVDD FV +D +
Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
Query: 66 SQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSE 113
S+R+EPR PW+ + W Q ++++K VD T+ +N S+
Sbjct: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 92.0 bits (227), Expect = 7e-19
Identities = 67/223 (30%), Positives = 103/223 (46%), Gaps = 18/223 (8%)
Query: 119 IQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSW----TAADMAAQITKRKWEAA 174
IQ+ GC++ S G+ + Q AY G D+++ + SW A +MA K +
Sbjct: 113 IQVTGGCELHS-GKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNMAKHFCKVLNQNQ 169
Query: 175 HEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPI-SDHEATLRCWALGFY 233
HE + L TC ++ L+ GK LQR P+ ++H P L C GFY
Sbjct: 170 HENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFY 229
Query: 234 PAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLP-K 292
P + + W R GE + Q T+ + P+ DGT+ A + V +GE +C V+H L +
Sbjct: 230 PKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQ 288
Query: 293 PLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRK 335
+ L WE S I+ +I L+LL + +W RK
Sbjct: 289 DIVLYWEHHSSVGFIILAVIVPLLLL--------IGLALWFRK 323
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 73.6 bits (179), Expect = 3e-13
Identities = 52/194 (26%), Positives = 81/194 (41%), Gaps = 11/194 (5%)
Query: 134 LRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEA-EQLRAYLDGTCVEWL 192
+RG + Y+ ++Y + D+ + A W + E E+ RA +D C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVC---R 112
Query: 193 RRYLENGKETLQRTDPPKTHMTHHPIS--DHEATLRCWALGFYPAEITLTWQRDGEDQTQ 250
Y + TLQR P ++ +H L C FYPA+I + W R+ +++T
Sbjct: 113 HNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETA 172
Query: 251 DTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPT----- 305
GD TFQ + + YTCHV+H L P+T+ W S+
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKML 232
Query: 306 IPIVGIIAGLVLLG 319
I G + GL+ LG
Sbjct: 233 SGIGGFVLGLIFLG 246
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 72.4 bits (176), Expect = 6e-13
Identities = 52/194 (26%), Positives = 80/194 (41%), Gaps = 11/194 (5%)
Query: 134 LRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEA-EQLRAYLDGTCVEWL 192
+RG + Y+ ++Y + D+ + A W + E E+ RA LD C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVC---R 112
Query: 193 RRYLENGKETLQRTDPPKTHMTHHPIS--DHEATLRCWALGFYPAEITLTWQRDGEDQTQ 250
Y + TLQR P ++ +H L C FYPA+I + W R+ +++T
Sbjct: 113 HNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETT 172
Query: 251 DTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPT----- 305
GD TFQ + + YTCHV+H L P+ + W S+
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKML 232
Query: 306 IPIVGIIAGLVLLG 319
I G + GL+ LG
Sbjct: 233 SGIGGFVLGLIFLG 246
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 72.4 bits (176), Expect = 6e-13
Identities = 52/194 (26%), Positives = 80/194 (41%), Gaps = 11/194 (5%)
Query: 134 LRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEA-EQLRAYLDGTCVEWL 192
+RG + Y+ ++Y + D+ + A W + E E+ RA LD C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVC---R 112
Query: 193 RRYLENGKETLQRTDPPKTHMTHHPIS--DHEATLRCWALGFYPAEITLTWQRDGEDQTQ 250
Y + TLQR P ++ +H L C FYPA+I + W R+ +++T
Sbjct: 113 HNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETT 172
Query: 251 DTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPT----- 305
GD TFQ + + YTCHV+H L P+ + W S+
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKML 232
Query: 306 IPIVGIIAGLVLLG 319
I G + GL+ LG
Sbjct: 233 SGIGGFVLGLIFLG 246
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 71.6 bits (174), Expect = 1e-12
Identities = 57/216 (26%), Positives = 90/216 (41%), Gaps = 13/216 (6%)
Query: 132 RFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEA-EQLRAYLDGTCVE 190
RFL Y Y+ +++ + D+ + A + W + + E+ RA D C
Sbjct: 52 RFLERY---IYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMC-- 106
Query: 191 WLRRYLENGKETLQRTDPPKTHMTHH---PISDHEATLRCWALGFYPAEITLTWQRDGED 247
Y G TLQR P+ +++ P+ H L C FYP I + W +G++
Sbjct: 107 -RHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNL-LVCHVTDFYPGSIQVRWFLNGQE 164
Query: 248 QTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIP 307
+T GD TFQ + + + YTC V+H L P+T+ W+ S
Sbjct: 165 ETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARS 224
Query: 308 IVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGS 343
AG +LG +I G V M RR ++G +
Sbjct: 225 KTLTGAGGFVLGLIICG--VGIFMHRRSKKVQRGSA 258
>gi|239758095 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 71.6 bits (174), Expect = 1e-12
Identities = 49/186 (26%), Positives = 79/186 (42%), Gaps = 11/186 (5%)
Query: 142 YDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEA-EQLRAYLDGTCVEWLRRYLENGK 200
Y+ ++ + + D+ + A + W + + E+ RA +D C Y +
Sbjct: 64 YNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVC---RHNYQLELR 120
Query: 201 ETLQRTDPPKTHMTHHPIS--DHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETR 258
TLQR P ++ +H L C FYPA+I + W R+G+++T
Sbjct: 121 TTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLI 180
Query: 259 PAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPT-----IPIVGIIA 313
GD TFQ + + YTCHV+H L P+T+ W S+ I G +
Sbjct: 181 RNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVL 240
Query: 314 GLVLLG 319
GL+ LG
Sbjct: 241 GLIFLG 246
>gi|239740749 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 71.6 bits (174), Expect = 1e-12
Identities = 49/186 (26%), Positives = 79/186 (42%), Gaps = 11/186 (5%)
Query: 142 YDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEA-EQLRAYLDGTCVEWLRRYLENGK 200
Y+ ++ + + D+ + A + W + + E+ RA +D C Y +
Sbjct: 64 YNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVC---RHNYQLELR 120
Query: 201 ETLQRTDPPKTHMTHHPIS--DHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETR 258
TLQR P ++ +H L C FYPA+I + W R+G+++T
Sbjct: 121 TTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLI 180
Query: 259 PAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPT-----IPIVGIIA 313
GD TFQ + + YTCHV+H L P+T+ W S+ I G +
Sbjct: 181 RNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVL 240
Query: 314 GLVLLG 319
GL+ LG
Sbjct: 241 GLIFLG 246
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,692,344
Number of Sequences: 37866
Number of extensions: 679968
Number of successful extensions: 1985
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 1753
Number of HSP's gapped (non-prelim): 173
length of query: 365
length of database: 18,247,518
effective HSP length: 104
effective length of query: 261
effective length of database: 14,309,454
effective search space: 3734767494
effective search space used: 3734767494
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.