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Search of human proteins with 24041035
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24041035 notch 2 preproprotein [Homo sapiens]
(2471 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24041035 notch 2 preproprotein [Homo sapiens] 5402 0.0
gi|148833508 notch1 preproprotein [Homo sapiens] 2885 0.0
gi|134244285 Notch homolog 3 [Homo sapiens] 2016 0.0
gi|55770876 notch4 preproprotein [Homo sapiens] 1258 0.0
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 593 e-169
gi|4557679 jagged 1 precursor [Homo sapiens] 526 e-148
gi|24430141 fibrillin 1 precursor [Homo sapiens] 520 e-147
gi|66346695 fibrillin 2 precursor [Homo sapiens] 508 e-143
gi|56237021 fibrillin 3 precursor [Homo sapiens] 498 e-140
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 496 e-139
gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens] 489 e-137
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 460 e-129
gi|122937283 6720455I24Rik homolog [Homo sapiens] 455 e-127
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 405 e-112
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 366 e-100
gi|112420992 crumbs homolog 2 [Homo sapiens] 324 6e-88
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 305 5e-82
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 277 8e-74
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 277 8e-74
gi|110735443 delta-like 1 [Homo sapiens] 271 8e-72
gi|148886654 polydom [Homo sapiens] 271 8e-72
gi|4557733 latent transforming growth factor beta binding protei... 261 6e-69
gi|110347437 latent transforming growth factor beta binding prot... 255 3e-67
gi|110347412 latent transforming growth factor beta binding prot... 255 3e-67
gi|110347431 latent transforming growth factor beta binding prot... 255 3e-67
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 253 2e-66
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 253 2e-66
gi|46249414 latent transforming growth factor beta binding prote... 233 2e-60
gi|46249412 latent transforming growth factor beta binding prote... 233 2e-60
gi|153946395 tenascin C precursor [Homo sapiens] 227 1e-58
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 5402 bits (14013), Expect = 0.0
Identities = 2471/2471 (100%), Positives = 2471/2471 (100%)
Query: 1 MPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE 60
MPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE
Sbjct: 1 MPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE 60
Query: 61 YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT 120
YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT
Sbjct: 61 YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT 120
Query: 121 CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE 180
CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
Sbjct: 121 CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE 180
Query: 181 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG 240
TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG
Sbjct: 181 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG 240
Query: 241 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD 300
DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
Sbjct: 241 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD 300
Query: 301 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF 360
ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
Sbjct: 301 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF 360
Query: 361 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA 420
SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
Sbjct: 361 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA 420
Query: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC 480
MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
Sbjct: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC 480
Query: 481 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP 540
LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
Sbjct: 481 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP 540
Query: 541 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM 600
CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
Sbjct: 541 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM 600
Query: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660
GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660
Query: 661 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ 720
DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ
Sbjct: 661 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ 720
Query: 721 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780
VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
Sbjct: 721 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780
Query: 781 CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN 840
CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN
Sbjct: 781 CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN 840
Query: 841 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP 900
PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP
Sbjct: 841 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP 900
Query: 901 PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN 960
PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN
Sbjct: 901 PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN 960
Query: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS 1020
GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS 1020
Query: 1021 FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ 1080
FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ
Sbjct: 1021 FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ 1080
Query: 1081 KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG 1140
KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG
Sbjct: 1081 KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG 1140
Query: 1141 YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG 1200
YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
Sbjct: 1141 YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG 1200
Query: 1201 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER 1260
TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER
Sbjct: 1201 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER 1260
Query: 1261 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA 1320
CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA
Sbjct: 1261 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA 1320
Query: 1321 VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCAS 1380
VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCAS
Sbjct: 1321 VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCAS 1380
Query: 1381 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCD 1440
SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCD
Sbjct: 1381 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCD 1440
Query: 1441 EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNS 1500
EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNS
Sbjct: 1441 EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNS 1500
Query: 1501 KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQ 1560
KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQ
Sbjct: 1501 KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQ 1560
Query: 1561 DARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAG 1620
DARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAG
Sbjct: 1561 DARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAG 1620
Query: 1621 SKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLY 1680
SKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLY
Sbjct: 1621 SKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLY 1680
Query: 1681 LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNL 1740
LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNL
Sbjct: 1681 LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNL 1740
Query: 1741 SVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIR 1800
SVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIR
Sbjct: 1741 SVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIR 1800
Query: 1801 RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIIT 1860
RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIIT
Sbjct: 1801 RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIIT 1860
Query: 1861 DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA 1920
DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
Sbjct: 1861 DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA 1920
Query: 1921 DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA 1980
DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
Sbjct: 1921 DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA 1980
Query: 1981 LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD 2040
LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
Sbjct: 1981 LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD 2040
Query: 2041 HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG 2100
HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
Sbjct: 2041 HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG 2100
Query: 2101 KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTY 2160
KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTY
Sbjct: 2101 KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTY 2160
Query: 2161 VSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPS 2220
VSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPS
Sbjct: 2161 VSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPS 2220
Query: 2221 VSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHP 2280
VSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHP
Sbjct: 2221 VSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHP 2280
Query: 2281 GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMY 2340
GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMY
Sbjct: 2281 GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMY 2340
Query: 2341 QIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER 2400
QIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
Sbjct: 2341 QIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER 2400
Query: 2401 TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS 2460
TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS
Sbjct: 2401 TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS 2460
Query: 2461 EPPHNNMQVYA 2471
EPPHNNMQVYA
Sbjct: 2461 EPPHNNMQVYA 2471
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 2885 bits (7479), Expect = 0.0
Identities = 1381/2563 (53%), Positives = 1713/2563 (66%), Gaps = 150/2563 (5%)
Query: 6 PALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR 65
P LL LL L L A A +C E C+N G C NGT C C F+G CQ
Sbjct: 2 PPLLAPLLCLALLPALAARGPRCSQPGETCLNGGKCEAA-NGTEACVCGGAFVGPRCQDP 60
Query: 66 DPCEKNRCQNGGTCVAQAMLGKA--TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHM 123
+PC C+N GTC G A C CA GF+G C + C ++ PC NGGTC +
Sbjct: 61 NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNAC-LTNPCRNGGTCDL 119
Query: 124 LSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDV 183
L+ Y+C C G++GK CQ D C S+PCANG C + C C F G C DV
Sbjct: 120 LTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDV 179
Query: 184 NEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDF 242
NEC PG C+HGGTC N GSY+C C TG C+ YVPC+PSPC NGGTCR TGD
Sbjct: 180 NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDV 239
Query: 243 TFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDEC 302
T EC CLPGF G CE NIDDCP + C+NGG CVDGVNTYNCRCPP+WTGQ+CTEDVDEC
Sbjct: 240 THECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDEC 299
Query: 303 LLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSC 362
L PNACQNGGTC N +GGY CVCVNGW+G+DCSENIDDCA A+C G+TC DRVASF C
Sbjct: 300 QLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC 359
Query: 363 MCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA 422
CP G+ GLLCHL+DACISNPC++G+ CDTNP+NG+ ICTCP GY G C++DVDEC++
Sbjct: 360 ECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLG 419
Query: 423 NSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLC 482
+NPCEHAGKC+NT G+F C+CL+GY GPRCE+D+NEC S+PCQNDATCLD+IG F C+C
Sbjct: 420 -ANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCIC 478
Query: 483 MPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCL 542
MPG++GVHCE+ +EC S+PC++NG+C+DK+N FQC CP GFTG +CQ D+D+C+STPC
Sbjct: 479 MPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCK 538
Query: 543 NGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGA 602
NGAKC+D PN Y C C G+TG CE +ID CDPDPCH+G C+DG+ ++TC+C PGY G
Sbjct: 539 NGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGH 598
Query: 603 ICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDG 662
C I+EC S PC + G C D N Y C C GT+G NCEIN DDCAS+PC G C+D
Sbjct: 599 HCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDK 658
Query: 663 INRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVN 722
I+ Y C C PG+TG CNI+IDECA NPC G TC +G+NGF C CPEG H P+C S+VN
Sbjct: 659 IDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVN 718
Query: 723 ECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCT 782
EC SNPC+HG C L+GYKC CD GW G NC+++ NEC SNPC NGGTC ++ +GY CT
Sbjct: 719 ECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCT 778
Query: 783 CKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPC 842
C++GF G NCQ NI+ECASNPCLNQGTC DD++GY C+C+LPYTG C+ VLAPC+P+PC
Sbjct: 779 CREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPC 838
Query: 843 ENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPG 902
N C++S ++ES++C+C GWQGQ C +DI+EC+ PC + C NT G Y C C G
Sbjct: 839 RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAG 898
Query: 903 FSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGG 962
+SG +CE DIDDC NPC NGGSC DG+NT C CLPGF G C+ D+NEC S+PC+NG
Sbjct: 899 YSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGA 958
Query: 963 TCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC 1022
C+D V+SYTC C AGF G+HCENN +CTESSCFNGGTCVDGINSF+CLCP GFTGS+C
Sbjct: 959 NCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYC 1018
Query: 1023 LHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKK 1082
H++NEC S PCL+ GTC DG G+YRC+CP GYTG NCQ LV+ C SPCKN G C Q
Sbjct: 1019 QHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTH 1078
Query: 1083 AESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT 1142
+ +C CPSGW G YCDVP+VSC++AA R+GV V LCQH G+C++AGNTH+C+C GYT
Sbjct: 1079 TQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT 1138
Query: 1143 GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC 1202
GSYCE+ +DEC+ +PCQ+GATC+D++GGY C+CV GY GVNC E+DEC + PCQNGGTC
Sbjct: 1139 GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC 1198
Query: 1203 IDLVNHFKCSCPPGTRGLLCEENIDDC-------ARGPHCLNGGQCMDRIGGYSCRCLPG 1255
+DL N +KCSCP GT+G+ CE N+DDC +R P C N G C+D++GGYSC C PG
Sbjct: 1199 LDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPG 1258
Query: 1256 FAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLN 1315
F GERCEGD+NECLSNPC + G+ +C+Q ND+ C CR+ TGR CE+ ++ C PC N
Sbjct: 1259 FVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN 1318
Query: 1316 GGTCAVASNMPDGFICRCPPGFSGARCQS---SCGQVKCRKGEQCVHTASGPRCFCPSP- 1371
GGTCAVASN GFIC+CP GF GA C++ +CG ++C G C+ P C C P
Sbjct: 1319 GGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPF 1378
Query: 1372 --RDCESGCAS-----SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELY---------- 1414
+C+ +S +PC + G+C P + P+Y C C F+G C +
Sbjct: 1379 TGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGR 1438
Query: 1415 TAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWD 1474
PP C C + A + VC CN+HAC WDGGDCSL +PW NC+ L CW
Sbjct: 1439 DIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWK 1498
Query: 1475 YINN-QCDELCNTVECLFDNFECQGNSKTCK--YDKYCADHFKDNHCDQGCNSEECGWDG 1531
Y ++ CD CN+ CLFD F+CQ C YD+YC DHF D HCDQGCNS EC WDG
Sbjct: 1499 YFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDG 1558
Query: 1532 LDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRALGTLLHTNLRIKRDSQGELMVYP 1591
LDCA PE LA GTLV+VVLMPPEQL + FLR L +LHTN+ KRD+ G+ M++P
Sbjct: 1559 LDCAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFP 1618
Query: 1592 YYGEKSAAMKKQRMTRRS-----------------LPGEQE----------QEVAGSKVF 1624
YYG + ++K + R + LPG E +V GS V+
Sbjct: 1619 YYG-REEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSEGGRRRRELDPMDVRGSIVY 1677
Query: 1625 LEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLS--YPLVSVVSESLTPERTQLLYLL 1682
LEIDNRQCVQ S CF++ AA L + A G+L+ Y + +V SE++ P L+ +
Sbjct: 1678 LEIDNRQCVQASSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPAQLHFM 1737
Query: 1683 --AVAVVIILFIILLGVIMA-KRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKN 1739
A A ++LF + GV+++ KR+R+HG LW PEGF + +AS KRREP+G+D+VGLK
Sbjct: 1738 YVAAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKV-SEASKKKRREPLGEDSVGLKP 1796
Query: 1740 LSVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADI 1799
L S+ L+ +E W DE + KK + E+ +L + DD D R WTQQHL+AAD+
Sbjct: 1797 LK-NASDGALMDDNQNE-W-GDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADL 1853
Query: 1800 RRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANII 1859
R + ++A TPPQ E + D +DVNVRGPDG TPLM+AS GG + + +E+ ED+ A +I
Sbjct: 1854 RMS-AMAPTPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEE-EDAPA-VI 1910
Query: 1860 TDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVA 1919
+D +YQGASL QTDRTGE ALHLAARYSR+DAAKRLL+A ADAN QDNMGR PLHAAV+
Sbjct: 1911 SDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVS 1970
Query: 1920 ADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKS 1979
ADAQGVFQILIRNR TDLDARM+DGTTPLILAARLAVEGM+ +LIN ADVNAVDD GKS
Sbjct: 1971 ADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKS 2030
Query: 1980 ALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDIT 2039
ALHWAAAVNNV+A ++LLKNGAN+DMQ+N+EETPLFLAAREGSYE AK+LLDHFANRDIT
Sbjct: 2031 ALHWAAAVNNVDAAVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDIT 2090
Query: 2040 DHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPP--GTVL--TSALSPVICGPNRSFLSLK 2095
DHMDRLPRD+A++RMHHDIVRLLDEYN+ SP G L T LSP +C PN SLK
Sbjct: 2091 DHMDRLPRDIAQERMHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLK 2150
Query: 2096 HTPMGKKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLE 2155
GKK R+PS+K L +KEAKD K +RRKKS K L +SS LSPVDSLE
Sbjct: 2151 PGVQGKKVRKPSSK-----GLACGSKEAKDLK-ARRKKSQDGKGCLLDSSGMLSPVDSLE 2204
Query: 2156 SPHTYVSDTTSSPMITSPGILQASPNPML--ATAAPPAPVHAQHALSFSNLHEMQPLAHG 2213
SPH Y+SD S P++ SP Q SP+ L P + H L+ + EM L G
Sbjct: 2205 SPHGYLSDVASPPLLPSP--FQQSPSVPLNHLPGMPDTHLGIGH-LNVAAKPEMAALGGG 2261
Query: 2214 ASTVLPSVSQLLSHHHIVSP-----GSGSAGSLS----RLHPVPVPADWMNRME--VNET 2262
+ LSH + S GS S G+L+ + +W++R++ +
Sbjct: 2262 GRLAFETGPPRLSHLPVASGTSTVLGSSSGGALNFTVGGSTSLNGQCEWLSRLQSGMVPN 2321
Query: 2263 QYNEMFGMVLAPAEGTHPGIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIA------ 2316
QYN + G V AP + + Q H + L ++++Q +P +A
Sbjct: 2322 QYNPLRGSV-APGPLSTQAPSLQHGMVGPLHSSLAASALSQMMSYQGLPSTRLATQPHLV 2380
Query: 2317 -----------------QPAGAPQPQSTCPP------------AVAGPLPTMYQIPEMAR 2347
QPA Q QS PP A +G L + E ++
Sbjct: 2381 QTQQVQPQNLQMQQQNLQPANIQQQQSLQPPPPPPQPHLGVSSAASGHLGRSFLSGEPSQ 2440
Query: 2348 L------PSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAERT 2401
PS ++P Q+ T LP+ P + ++ TPPSQHSY S+ + T
Sbjct: 2441 ADVQPLGPSSLAVHTILP-QESPALPTSLPSSLVPPVTAAQFLTPPSQHSY--SSPVDNT 2497
Query: 2402 PSHSGHLQGEHPYLTPSPESPDQWSSSSPHS-ASDWSDVTTSP 2443
PSH + EHP+LTPSPESPDQWSSSSPHS SDWS+ +SP
Sbjct: 2498 PSHQLQVP-EHPFLTPSPESPDQWSSSSPHSNVSDWSEGVSSP 2539
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 2016 bits (5223), Expect = 0.0
Identities = 1047/2336 (44%), Positives = 1371/2336 (58%), Gaps = 194/2336 (8%)
Query: 152 PCANGSTCTTV-ANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL----PGSYQ 206
PCANG CT + + + +C C G+ G++C+ + + C G C G C + +
Sbjct: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCH-SGPCAGRGVCQSSVVAGTARFS 105
Query: 207 CQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCP- 265
C+CP+GF G C SL PC SPC +G C D F C+C PG++G +C ++D+C
Sbjct: 106 CRCPRGFRGPDC-SLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRV 164
Query: 266 NHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG---Y 322
C++GG C++ ++ C+CP +TG C C P+ C+NGGTC R G Y
Sbjct: 165 GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCA--PSPCRNGGTC--RQSGDLTY 220
Query: 323 GCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DACIS 381
C C+ G+ G +C N+DDC C G TC+D V +++C CP G C D D C
Sbjct: 221 DCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQL 280
Query: 382 NP--CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGA 439
P CH G C N L G + C C G+ G C++++D+CA A C H C + +
Sbjct: 281 QPNACHNGGTC-FNTLGG-HSCVCVNGWTGESCSQNIDDCATA---VCFHGATCHDRVAS 335
Query: 440 FHCECLKGYAGPRCEMDINECHSDPCQNDATC-LDKIGGFT-CLCMPGFKGVHCELEINE 497
F+C C G G C +D + C S+PC DA C + + G C C PGF G C+ +++E
Sbjct: 336 FYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDE 394
Query: 498 CQ--SNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYE 555
C +NPC + G+CV+ F C C G+TGP C+ D+++C S PC N A C+D +
Sbjct: 395 CSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFT 454
Query: 556 CQCATGFTGVLCEENIDNCDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSS 614
C C GFTG CE +ID C PC + G C+D ++ ++C C G+ G+ C +DEC S+
Sbjct: 455 CICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAST 514
Query: 615 PCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGF 674
PC N +C+D +GY+C C G G C+ N DDC+ +PC HG C+DGI +SC C+PG+
Sbjct: 515 PCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGY 574
Query: 675 TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNC 734
TG RC +DEC S PCR G C++ V+ + C CP G +C +++C SNPC G C
Sbjct: 575 TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVC 634
Query: 735 TGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRC------------- 781
G++ Y C+C G+ G C V+ NEC S+PC GG+C + NG+RC
Sbjct: 635 RDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP 694
Query: 782 ------------------------TCKKGFKGYNCQVNI--DECASNPCLNQGTCFDDIS 815
C+ G+ G C ++ D C S PC GTC D
Sbjct: 695 PSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGM 754
Query: 816 GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDID 875
G+ C C G+ C+ +L+PC+PNPCE+ C+ +P + C C GWQG RC D+D
Sbjct: 755 GFHCTCPPGVQGRQCE-LLSPCTPNPCEHGGRCESAPG-QLPVCSCPQGWQGPRCQQDVD 812
Query: 876 ECISK-PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS 934
EC PC HG+C N GS+ C C G++G C++DI+DC NPC NGGSC DGV +FS
Sbjct: 813 ECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFS 872
Query: 935 CLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTES 994
C CLPGF G +C D++ECLS PC GTC+D+V S+TC C G+ G HCE ++ +C+ S
Sbjct: 873 CSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPS 931
Query: 995 SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLG 1054
SCFNGGTCVDG+NSFSCLC G+TG+ C HE + C S PCL+ G C +RC+C
Sbjct: 932 SCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES 991
Query: 1055 YTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGV 1114
+TG CQTLV+ CSR PC+N G CVQ A CLCP GW+G CD+ ++ C AA++ GV
Sbjct: 992 FTGPQCQTLVDWCSRQPCQNGGRCVQTGA--YCLCPPGWSGRLCDIRSLPCREAAAQIGV 1049
Query: 1115 LVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCE 1174
+E LCQ G C++ ++HYC CP G TGS+CE+++D C + PCQHG TC ++GGY CE
Sbjct: 1050 RLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCE 1109
Query: 1175 CVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCA---- 1230
C+PGY G NCE +VDEC +QPCQ+GG+CIDLV + CSCPPGT G+LCE N DDC
Sbjct: 1110 CLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPP 1169
Query: 1231 --RGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTND- 1287
GP CL+ G C+D +GG+ C C PG+ G RCE DINEC S C + + DC+Q
Sbjct: 1170 LDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGG 1229
Query: 1288 YLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDG--FICRCPPGFSGARCQS- 1344
+ C+C + F+G C+T + C PC +GG C + G F C C F G RC+
Sbjct: 1230 FRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERV 1289
Query: 1345 --SCGQVKCRKGEQCVHTASGPRCFCPS--------------PRDCESGCASSPCQHGGS 1388
SC +++C G C T GPRC CP P + CA++PC HGGS
Sbjct: 1290 ARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGS 1349
Query: 1389 CHPQRQPPYYSCQCAPPFSGSRCELYTAPPS-TPPATCLSQYCADKARDGVCDEACNSHA 1447
C P P++ C CA ++G RCE A P + C C K D CD CNS
Sbjct: 1350 CRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPG 1409
Query: 1448 CQWDGGDCSLTMENPWANCSSPLPCWDYINN-QCDELCNTVECLFDNFECQ--GNSKTCK 1504
C WDGGDCSL++ +PW C + L CW NN +CD C++ CL+DNF+C G +TC
Sbjct: 1410 CGWDGGDCSLSVGDPWRQCEA-LQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCN 1468
Query: 1505 --YDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDA 1562
Y+KYCADHF D CDQGCN+EECGWDGLDCA++ P LA G LV+ VL+PPE+LL+ +
Sbjct: 1469 PVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEVPALLARGVLVLTVLLPPEELLRSS 1528
Query: 1563 RSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAGSK 1622
FL+ L +L T+LR + D+ G+ MV+PY+ + + R E EV GS
Sbjct: 1529 ADFLQRLSAILRTSLRFRLDAHGQAMVFPYHRPSPGSEPRARR-------ELAPEVIGSV 1581
Query: 1623 VFLEIDNRQCVQ--DSDHCFKNTDAAAALLASHAIQGTLS--YPLVSVVSESLTPERTQ- 1677
V LEIDNR C+Q ++DHCF + +AA L + + L YPL V E L P
Sbjct: 1582 VMLEIDNRLCLQSPENDHCFPDAQSAADYLGALSAVERLDFPYPLRDVRGEPLEPPEPSV 1641
Query: 1678 -LLYLLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRD-ASNHK-RREPVGQDA 1734
LL LL V++L I++LGV++A+RKR+H +LW PEGF+L +D AS HK RREPVGQDA
Sbjct: 1642 PLLPLLVAGAVLLLVILVLGVMVARRKREHSTLWFPEGFSLHKDVASGHKGRREPVGQDA 1701
Query: 1735 VGLKNLSVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHL 1794
+G+KN++ S + T W+D E P+ K++K E+ + +EE +D R WTQ HL
Sbjct: 1702 LGMKNMAKGESLMGEVATD----WMDTECPEAKRLKVEEPGMGAEE--AVDCRQWTQHHL 1755
Query: 1795 EAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSD-LSDEDEDAED 1853
AADIR P++ALTPPQ + + D +DVNVRGPDG TPLMLAS GG+ + + E+++A+D
Sbjct: 1756 VAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFCGGALEPMPTEEDEADD 1815
Query: 1854 SSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCP 1913
+SA+II+DL+ QGA L A+TDRTGE ALHLAARY+RADAAKRLLDAGAD NAQD+ GR P
Sbjct: 1816 TSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTP 1875
Query: 1914 LHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAV 1973
LH AV ADAQGVFQILIRNR TDLDARM DG+T LILAARLAVEGMV ELI ADVNAV
Sbjct: 1876 LHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAV 1935
Query: 1974 DDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHF 2033
D+ GKSALHWAAAVNNVEATL LLKNGAN+DMQD+KEETPLFLAAREGSYEAAK+LLDHF
Sbjct: 1936 DELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHF 1995
Query: 2034 ANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLS 2093
ANR+ITDH+DRLPRDVA++R+H DIVRLLD+ + SPPG L P++C P
Sbjct: 1996 ANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGPRSPPG---PHGLGPLLCPPGAFLPG 2052
Query: 2094 LKHTPMG-KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVD 2152
LK G KKSRRP K+ + P +G +K +L+ L++SSVTLSPVD
Sbjct: 2053 LKAAQSGSKKSRRPPGKAGLGPQGP---------RGRGKKLTLACPGPLADSSVTLSPVD 2103
Query: 2153 SLESPHTYVSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAH 2212
SL+SP + G ASP P+ +A + + + L
Sbjct: 2104 SLDSPRPF-------------GGPPASPGGF--------PLEGPYAAATATAVSLAQLGG 2142
Query: 2213 GASTVLPSVSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVL 2272
L P G SL L+PV VP DW F + L
Sbjct: 2143 PGRAGLGR-----------QPPGGCVLSLGLLNPVAVPLDWARLPP--PAPPGPSFLLPL 2189
Query: 2273 APA-EGTHPG--IAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQ-----PAGAPQP 2324
AP + +PG ++PQ RPP + E P PK + P P P
Sbjct: 2190 APGPQLLNPGTPVSPQERPPPYLAVPGHGEEYPAAGAHSSPPKARFLRVPSEHPYLTPSP 2249
Query: 2325 QSTCPPAVAGPLPTMYQIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASV 2380
+S P A P P PS A T M G LPA P P SV
Sbjct: 2250 ES--PEHWASPSPPSLS-DWSESTPSPATATGAMATTTG-----ALPA-QPLPLSV 2296
Score = 1418 bits (3670), Expect = 0.0
Identities = 672/1517 (44%), Positives = 852/1517 (56%), Gaps = 184/1517 (12%)
Query: 67 PC-EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCH--- 122
PC + + C NGG C Q +A C C G+ GE CQ PC S PC G C
Sbjct: 42 PCLDGSPCANGGRCT-QLPSREAACLCPPGWVGERCQLED--PCH-SGPCAGRGVCQSSV 97
Query: 123 MLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN-QFSCKCLTGFTGQKCET 181
+ + C C GF G +C D CLS PCA+G+ C+ + +F C C G+ G+ C +
Sbjct: 98 VAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS 157
Query: 182 DVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGD 241
DV+EC + C+HGGTCLN PGS++CQCP G+TG C++ VPCAPSPC NGGTCRQ+GD
Sbjct: 158 DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGD 217
Query: 242 FTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDE 301
T++C CLPGFEG CE N+DDCP HRC NGG CVDGVNTYNC+CPP+WTGQFCTEDVDE
Sbjct: 218 LTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDE 277
Query: 302 CLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFS 361
C LQPNAC NGGTC N GG+ CVCVNGW+G+ CS+NIDDCA A C G+TC DRVASF
Sbjct: 278 CQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFY 337
Query: 362 CMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAM 421
C CP GK GLLCHLDDAC+SNPCH+ A+CDTNP+NG+ ICTCP G+ G C +DVDEC++
Sbjct: 338 CACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSI 397
Query: 422 ANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCL 481
+NPCEH G+CVNT G+F C+C +GY GPRCE D+NEC S PC+N ATCLD+IG FTC+
Sbjct: 398 G-ANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCI 456
Query: 482 CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC 541
CM GF G +CE++I+ECQS+PCVN G C D+VN F C CP GF+G CQ+D+D+C+STPC
Sbjct: 457 CMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPC 516
Query: 542 LNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMG 601
NGAKC+D P+GYEC+CA GF G LC+ N+D+C PDPCHHG+C DGI S++C C PGY G
Sbjct: 517 RNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTG 576
Query: 602 AICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMD 661
C Q+DEC S PC + G+C+DLV+ Y C C GT+GVNCE+N DDCASNPC G+C D
Sbjct: 577 TRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRD 636
Query: 662 GINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV 721
GINRY CVC PGFTG CN++I+ECAS+PC +G +C++G NGFRC+CP G P C
Sbjct: 637 GINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPS 696
Query: 722 NECLSNPCIHGNCTGGLSGYKCLCDAGWVGINC--EVDKNECLSNPCQNGGTCDNLVNGY 779
+ C PC HG C G++C+C+ GW G C + ++ C S PC+ GGTC + G+
Sbjct: 697 HPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGF 756
Query: 780 RCT--------------------------------------CKKGFKGYNCQVNIDECAS 801
CT C +G++G CQ ++DECA
Sbjct: 757 HCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAG 816
Query: 802 -NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCL 860
PC G C + ++C C YTG +C + C PNPC N C++ S++C
Sbjct: 817 PAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVG--SFSCS 874
Query: 861 CAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPC 920
C PG+ G RC D+DEC+S PC G C + S+ C CPPG+ G CE+D+ DC + C
Sbjct: 875 CLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSC 933
Query: 921 QNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD 980
NGG+C+DGVN+FSCLC PG+TG CQ + + CLS PC +GG CS + C C F
Sbjct: 934 FNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFT 993
Query: 981 GVHCENNINECTESSCFN------------------------------------------ 998
G C+ ++ C+ C N
Sbjct: 994 GPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQ 1053
Query: 999 ----GGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLG 1054
GG CVD +S C+CP G TGS C E++ C + PC + GTC +G Y C C G
Sbjct: 1054 LCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPG 1113
Query: 1055 YTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGV 1114
Y G NC+ V+ C+ PC++ G+C+ A C CP G G C++ C
Sbjct: 1114 YNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDS- 1172
Query: 1115 LVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFI----GG 1170
C H+G C++ C CP GYTG CE ++EC S C H A D + GG
Sbjct: 1173 --GPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGAC-HAAHTRDCLQDPGGG 1229
Query: 1171 YRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVN-----HFKCSCPPGTRGLLCEEN 1225
+RC C G+ G C+ + C++QPCQ+GG C F C C G CE
Sbjct: 1230 FRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERV 1289
Query: 1226 IDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE-------GDIN-ECLSNPCSSEG 1277
C R C G C G C C PG +G C G N C + PC G
Sbjct: 1290 ARSC-RELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGG 1348
Query: 1278 SLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF 1337
S L + C C +TG CE S P RCP
Sbjct: 1349 SCRPAPLAPFFRCACAQGWTGPRCEA------------PAAAPEVSEEP-----RCP--- 1388
Query: 1338 SGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCES-GCASSPCQHGGSCHPQRQPP 1396
A CQ+ G +C R+C S GC GG C P
Sbjct: 1389 -RAACQAKRGDQRC-------------------DRECNSPGCG----WDGGDCSLSVGDP 1424
Query: 1397 YYSC---QCAPPFSGSRCELYTAPPST-----------PPATC---LSQYCADKARDGVC 1439
+ C QC F+ SRC+ + P+ TC +YCAD DG C
Sbjct: 1425 WRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRC 1484
Query: 1440 DEACNSHACQWDGGDCS 1456
D+ CN+ C WDG DC+
Sbjct: 1485 DQGCNTEECGWDGLDCA 1501
Score = 783 bits (2021), Expect = 0.0
Identities = 427/1237 (34%), Positives = 590/1237 (47%), Gaps = 119/1237 (9%)
Query: 28 CRDGYEPCVNEGMCVTYHNGTG-------YCKCPEGFLGEYCQHRDPCEKNRCQNGGTCV 80
C + C V +H T YC CP G G C D C N C C
Sbjct: 311 CSQNIDDCAT---AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICD 367
Query: 81 AQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGK 140
+ G+A C C GFTG C + PC + G C + ++ ++ C C G+TG
Sbjct: 368 TNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRC-VNTQGSFLCQCGRGYTGP 426
Query: 141 ECQW-TDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL 199
C+ + CLS PC N +TC QF+C C+ GFTG CE D++EC C +GG C
Sbjct: 427 RCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQ-SSPCVNGGVCK 485
Query: 200 NLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCER 259
+ + C CP GF+G C CA +PC NG C D +EC C GFEG+ C+R
Sbjct: 486 DRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPD-GYECRCAEGFEGTLCDR 544
Query: 260 NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRN 319
N+DDC C +G CVDG+ +++C C P +TG C VDEC QP C++GG C +
Sbjct: 545 NVDDCSPDPCHHGR-CVDGIASFSCACAPGYTGTRCESQVDECRSQP--CRHGGKCLDLV 601
Query: 320 GGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DA 378
Y C C +G +G +C NIDDCA CT G C D + + C+C G G LC+++ +
Sbjct: 602 DKYLCRCPSGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFTGPLCNVEINE 660
Query: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438
C S+PC +G C + NG + C CP G C CA PC H G C + G
Sbjct: 661 CASSPCGEGGSC-VDGENG-FRCLCPPGSLPPLCLPPSHPCA---HEPCSH-GICYDAPG 714
Query: 439 AFHCECLKGYAGPRCEMDI--NECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEIN 496
F C C G++GPRC + + C S PC+ TC GF C C PG +G CEL ++
Sbjct: 715 GFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL-LS 773
Query: 497 ECQSNPCVNNGQCVDKVNRFQ-CLCPPGFTGPVCQIDIDDCSS-TPCLNGAKCIDHPNGY 554
C NPC + G+C + C CP G+ GP CQ D+D+C+ PC C + +
Sbjct: 774 PCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSF 833
Query: 555 ECQCATGFTGVLCEENIDNCDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQIDECYS 613
C C G+TG C+++I++CDP+PC + G CQDG+ S++C C PG+ G C+ +DEC S
Sbjct: 834 SCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLS 893
Query: 614 SPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIH-GICMDGINRYSCVCSP 672
+PC G C D V + C C PG G +CE + DC+ + C + G C+DG+N +SC+C P
Sbjct: 894 NPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRP 952
Query: 673 GFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIH- 731
G+TG C + D C S PC G C GFRC C E P C + V+ C PC +
Sbjct: 953 GYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNG 1012
Query: 732 GNCTGGLSGYKCLCDAGWVGINCEVDKNEC----------LSNPCQNGGTCDNLVNGYRC 781
G C +G CLC GW G C++ C L CQ GG C + + + C
Sbjct: 1013 GRCV--QTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYC 1070
Query: 782 TCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNP 841
C +G G +C+ +D C + PC + GTC + GY C C+ Y G NC+ + C+ P
Sbjct: 1071 VCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQP 1130
Query: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP-------CMNHGLCHNTQGS 894
C++ C + Y C C PG G C I+ D+C P C+++G C + G
Sbjct: 1131 CQHGGSCIDL--VARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGG 1188
Query: 895 YMCECPPGFSGMDCEEDIDDCLANPCQ--NGGSCM-DGVNTFSCLCLPGFTGDKCQTDMN 951
+ C CPPG++G+ CE DI++C + C + C+ D F CLC GF+G +CQT ++
Sbjct: 1189 FRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLS 1248
Query: 952 ECLSEPCKNGGTCSDYVN-----SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGI 1006
C S+PC++GG C ++TC C F G CE C E C G C
Sbjct: 1249 PCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTP 1308
Query: 1007 NSFSCLCPVGFTGSFCLH--------EINECSSHPCLNEGTCVDG--LGTYRCSCPLGYT 1056
C CP G +G C C++ PCL+ G+C +RC+C G+T
Sbjct: 1309 RGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWT 1368
Query: 1057 GKNCQ--TLVNLCSRSPCKNKGTCVQKKAESQC--LCPS---GWAGAYCDVP-------- 1101
G C+ S P + C K+ + +C C S GW G C +
Sbjct: 1369 GPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQC 1428
Query: 1102 ----------NVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD 1151
N CD A S L ++ H+G N Y YC D
Sbjct: 1429 EALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVY--------EKYC---AD 1477
Query: 1152 ECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEV 1188
A C G EC G+ G++C EV
Sbjct: 1478 HFADGRCDQGCNTE--------EC--GWDGLDCASEV 1504
Score = 75.5 bits (184), Expect = 6e-13
Identities = 134/546 (24%), Positives = 208/546 (38%), Gaps = 91/546 (16%)
Query: 1936 DLDARMNDGTTPLILAARL--AVEGM--------------VAELINCQADVNAVDDH-GK 1978
D++ R DG TPL+LA+ A+E M +++LI A + A D G+
Sbjct: 1781 DVNVRGPDGFTPLMLASFCGGALEPMPTEEDEADDTSASIISDLICQGAQLGARTDRTGE 1840
Query: 1979 SALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDI 2038
+ALH AA +A LL GA+ + QD+ TPL A + +IL+ + + D+
Sbjct: 1841 TALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRN-RSTDL 1899
Query: 2039 TDHMDR------LPRDVARDRMHHDIVRLLDEYNVTPSPPGTVL---------TSALSPV 2083
M L +A + M +++ + N + L + L+ +
Sbjct: 1900 DARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALL 1959
Query: 2084 ICGPNRSFLSLKH-TPMGKKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLS 2142
G N+ K TP+ +R S ++ L + A R + ++++ +L
Sbjct: 1960 KNGANKDMQDSKEETPLFLAAREGSYEAAK-LLLDHFANREITDHLDRLPRDVAQE-RLH 2017
Query: 2143 ESSVTLSPVDSLESPHTYVSDTTSSPMITSPGI----LQASPNPMLATAAPPAPVHAQHA 2198
+ V L +D P + P++ PG L+A+ + + PP
Sbjct: 2018 QDIVRL--LDQPSGPRSPPGPHGLGPLLCPPGAFLPGLKAAQSGSKKSRRPPGK------ 2069
Query: 2199 LSFSNLHEMQPLAHGASTVLPSVSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRME 2258
+ L P G L L +SP SL P P
Sbjct: 2070 ---AGLGPQGPRGRGKKLTLACPGPLADSSVTLSP----VDSLDSPRPFGGPPASPGGFP 2122
Query: 2259 VNETQYNEMFGMVLAPAEGTHPGIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQP 2318
+ E Y ++ A+ PG A R P G + + + P
Sbjct: 2123 L-EGPYAAATATAVSLAQLGGPGRAGLGRQPPGGCVLSL----------------GLLNP 2165
Query: 2319 AGAPQPQSTCPPAVAGPLPTMYQIPEMARLPSVAFP-TAMMPQQDGQVAQTILPAYHPFP 2377
P + PP A P P+ + +P +A P + P T + PQ+ P Y P
Sbjct: 2166 VAVPLDWARLPPP-APPGPS-FLLP-LAPGPQLLNPGTPVSPQERP-------PPYLAVP 2215
Query: 2378 ASVGKYPTPPSQHSYASSNAAERTPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWS 2437
+YP + HS R PS EHPYLTPSPESP+ W+S SP S SDWS
Sbjct: 2216 GHGEEYPAAGA-HSSPPKARFLRVPS-------EHPYLTPSPESPEHWASPSPPSLSDWS 2267
Query: 2438 DVTTSP 2443
+ T SP
Sbjct: 2268 ESTPSP 2273
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 1258 bits (3254), Expect = 0.0
Identities = 696/1864 (37%), Positives = 964/1864 (51%), Gaps = 147/1864 (7%)
Query: 269 CQNGGVCVD-GVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC------------ 315
C NGG C+ + C+C P + G+ C + D C CQNGG+C
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETC-QFPDPCQ-NAQLCQNGGSCQALLPAPLGLPS 92
Query: 316 --ANRNGGYGCVCVNGWSGDDCSENIDD-CAFASCTPGSTC-IDRVASFSCMCPEGKAGL 371
+ + C C+ G++G+ C ++D C + C+ C I C C G G
Sbjct: 93 SPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGE 152
Query: 372 LCHLDDACISNPCHKGALC-DTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHA 430
C L D C +NPC G +C T P Q C CP G++G C DV+EC + PC
Sbjct: 153 QCQLRDFCSANPCVNGGVCLATYP---QIQCHCPPGFEGHACERDVNEC-FQDPGPCPKG 208
Query: 431 GKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCL---DKIGGF-TCLCMPGF 486
C NT G+F C C G GPRCE+ C C N TC +K F CLC PGF
Sbjct: 209 TSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF 268
Query: 487 KGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP---CLN 543
G CE+ + C S+ C N G C D ++ + CLCP +TG C D+D+C + C N
Sbjct: 269 IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRN 328
Query: 544 GAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQ-CQDGIDSYTCICNPGYMGA 602
G C + + C C +G+ G CEEN+D+C C G C D + S++C+C PG G
Sbjct: 329 GGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGL 388
Query: 603 ICSDQIDECYSSPCLNDGRCID--LVNGYQCNCQPGTSGVNCEINFDDC-----ASNPCI 655
+C + D C S PC D +C L C CQPG SG C + D+C +PC
Sbjct: 389 LCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCE 447
Query: 656 HG-ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHH 714
HG C++ ++C+C PG+TG RC D +EC S PC G+TC++ + F C+CP G
Sbjct: 448 HGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEG 507
Query: 715 PSCYSQVNECLSNPCI-HGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCD 773
C + NEC S PC+ H +C L+G++C+C G+ G CE D +EC S+PC NGG C
Sbjct: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ 567
Query: 774 NLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTV 833
+ + C C GF+G CQ +DEC S+PC +C D + C C +TG+ C+
Sbjct: 568 DQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVP 627
Query: 834 LAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQG 893
L C+PN C+ +CK+ + CLC G G C D C +HG C +
Sbjct: 628 L--CAPNLCQPKQICKDQK--DKANCLCPDGSPG--CAPPEDNCTC----HHGHCQRSS- 676
Query: 894 SYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNEC 953
C C G++G +CE ++ C++ PC +GG+C + ++C C G+TG C +M C
Sbjct: 677 ---CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTAC 733
Query: 954 LSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLC 1013
S PC NGG+C+ Y C C G C+ + + C + CFNGGTCV+ +FSCLC
Sbjct: 734 HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLC 793
Query: 1014 PVGFTGSFCLHEIN-ECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPC 1072
+GF G C ++ C+ PC N TC D RC CP GYTG +CQTL++LC++ PC
Sbjct: 794 AMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPC 853
Query: 1073 KNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNT 1132
C+Q CLC GW G C++P SC AA +G+ V LC + G+C+++G +
Sbjct: 854 PRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPS 913
Query: 1133 HYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQ 1192
++C CP G+ GS C++ ++ C S PCQ+GATC GY C+C PGY G NC E+D CQ
Sbjct: 914 YFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQ 973
Query: 1193 NQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP-HCLNGGQCMDRIGGYSCR 1251
+QPC N GTC F C+CPPG GL CE ++D+C P H C + C+
Sbjct: 974 SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQ 1033
Query: 1252 CLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTN-DYLCVCRSAFTGRHCETFVDVCPQ 1310
CLPG G+ CE +I+ C S PC G+ + + ++C C F G C C
Sbjct: 1034 CLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGF 1093
Query: 1311 MPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFC-P 1369
C +GG C + S P GF RC C+ GP C P
Sbjct: 1094 HHCHHGGLC-LPSPKP-GFPPRC----------------------ACLSGYGGPDCLTPP 1129
Query: 1370 SPRDCESGCASSPCQHGGSCHPQR--QPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLS 1427
+P+ C SPC + GSC P + C C G RC+ A
Sbjct: 1130 APKGCG---PPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGA----------- 1175
Query: 1428 QYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCW-DYINNQCDELCNT 1486
+ C ++ DG CD C+ WDGGDCSL + +PW C S CW + + QC C++
Sbjct: 1176 KGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDS 1235
Query: 1487 VECLFDNFECQ-GNSKTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEG 1545
ECLFD ++C+ + T YD+YC DHF + HC++GCN+ ECGWDG DC + +
Sbjct: 1236 EECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGP 1295
Query: 1546 TLVIVVLMPPEQLLQDARSFLRALGTLLHTNLRIKRDSQGELMVYPYYG----EKSAAMK 1601
+L ++V++ P L Q + R L L L +++D G MVYPY G EK +
Sbjct: 1296 SLALLVVLSPPALDQQLFALARVLSLTLRVGLWVRKDRDGRDMVYPYPGARAEEKLGGTR 1355
Query: 1602 KQRMTRRSLP------GEQEQEVAGSKVFLEIDNRQCVQDSDHCFKNTDAA------AAL 1649
R+ P E + AG V + +D +C D D AA+
Sbjct: 1356 DPTYQERAAPQTQPLGKETDSLSAGFVVVMGVDLSRCGPDHPASRCPWDPGLLLRFLAAM 1415
Query: 1650 LASHAIQGTLSYPLVSVVSESLT-PERTQLLYLLAVAVVIILFIILLGVIMA-----KRK 1703
A A++ L PL++V + T P QL + + + V + ++ LG ++ +R+
Sbjct: 1416 AAVGALEPLLPGPLLAVHPHAGTAPPANQLPWPVLCSPVAGVILLALGALLVLQLIRRRR 1475
Query: 1704 RKHGSLWLPEGFTL--RRDASNHKRREPVGQDAVGLKNL--SVQVSEANLIGTGTSEHWV 1759
R+HG+LWLP GFT R ++ H+RR P+G+D++GLK L +V E ++
Sbjct: 1476 REHGALWLPPGFTRRPRTQSAPHRRRPPLGEDSIGLKALKPKAEVDEDGVVMC------- 1528
Query: 1760 DDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIRRTPSLALTPPQAEQEVDVL 1819
GP+ + E+ E P + W+ + P A+ P E E++
Sbjct: 1529 --SGPE----EGEEVGQAEETGPPSTCQLWSL----SGGCGALPQAAMLTPPQESEMEAP 1578
Query: 1820 DVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIITDLVYQGASLQAQTDRTGEM 1879
D++ RGPDG TPLM A G S + A L+ GA QA T TGE
Sbjct: 1579 DLDTRGPDGVTPLMSAVCCGEVQ--SGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGET 1636
Query: 1880 ALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDA 1939
LHLAAR+SR AA+RLL+AGA+ N D GR PLHAAVAADA+ V Q+L+R+R T +DA
Sbjct: 1637 PLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDA 1696
Query: 1940 RMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKN 1999
R DGTTPL+LAARLAVE +V ELI QADV A D GK+ALHWAAAVNN A LL+
Sbjct: 1697 RTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQA 1756
Query: 2000 GANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDVARDRMHHDIV 2059
GA++D QDN+E+TPLFLAAREG+ E A++LL A R++ D P DVA R H D++
Sbjct: 1757 GADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLL 1816
Query: 2060 RLLD 2063
LL+
Sbjct: 1817 TLLE 1820
Score = 1024 bits (2647), Expect = 0.0
Identities = 498/1190 (41%), Positives = 640/1190 (53%), Gaps = 68/1190 (5%)
Query: 6 PALLWALLALWLCCAAPAH--ALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ 63
P+LL LL L L C + L C EPC N G C++ G G C+C GFLGE CQ
Sbjct: 4 PSLLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQ 63
Query: 64 HRDPCEKNR-CQNGGTCVA--QAMLGKAT----------CRCASGFTGEDCQYSTSHPCF 110
DPC+ + CQNGG+C A A LG + C C GFTGE CQ PC
Sbjct: 64 FPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCP 123
Query: 111 VSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
S C G CH+ + +C+C G+TG++CQ D C ++PC NG C Q C C
Sbjct: 124 PSF-CSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHC 182
Query: 171 LTGFTGQKCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSP 229
GF G CE DVNEC PG C G +C N GS+QC CP G G C+ PC P
Sbjct: 183 PPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRG 242
Query: 230 CVNGGTCR--QTGDFTFE-CNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRC 286
C NGGTC+ D TF C C PGF G CE N D+C +H+CQNGG C DG++TY C C
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC 302
Query: 287 PPQWTGQFCTEDVDECLLQ-PNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFA 345
P WTG C+EDVDEC Q P C+NGGTC N G + CVCV+GW G C EN+DDC A
Sbjct: 303 PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAA 362
Query: 346 SCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQ 405
+C PGSTCIDRV SFSC+CP G+ GLLCHL+D C+S PCH A C TNPL G +C C
Sbjct: 363 TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQP 422
Query: 406 GYKGADCTEDVDECAMANS--NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSD 463
GY G C +D+DEC MA +PCEH G C+NT G+F+C C GY G RCE D NEC S
Sbjct: 423 GYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQ 482
Query: 464 PCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPG 523
PC +TCLD + F CLC PG +G CE+E NEC S PC+N+ C D +N FQC+C PG
Sbjct: 483 PCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPG 542
Query: 524 FTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG- 582
F+G C+ DID+C S+PC NG +C D P + C+C GF G C+ +D C DPC G
Sbjct: 543 FSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGA 602
Query: 583 QCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNC 642
C D ++ C+C G+ G +C ++ C + C C D + C C G+ G C
Sbjct: 603 SCLDLPGAFFCLCPSGFTGQLC--EVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--C 658
Query: 643 EINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVN 702
D+C C HG C R SCVC G+TG C ++ C S PC G TC +
Sbjct: 659 APPEDNCT---CHHGHC----QRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711
Query: 703 GFRCICPEGPHHPSCYSQVNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNEC 761
G+ C CP G P+C ++ C S PC++ G+C GY C C G C+ + C
Sbjct: 712 GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC 771
Query: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNI-DECASNPCLNQGTCFDDISGYTCH 820
+S PC NGGTC N + C C GF+G C+ + CA +PC N+ TC D G C
Sbjct: 772 VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCL 831
Query: 821 CVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC--- 877
C YTG +CQT++ C+ PC + C ++ S+ CLC GW G C + + C
Sbjct: 832 CPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKA 889
Query: 878 -------ISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGV 930
+S C N GLC ++ SY C CPPGF G C++ ++ C + PCQNG +CM
Sbjct: 890 ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 949
Query: 931 NTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINE 990
+ + C C PG+ G C +++ C S+PC N GTC+ + C C GF G+ CE +++E
Sbjct: 950 SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDE 1009
Query: 991 CTESSCFNGGT--CVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGT-- 1046
C + C GT C N+F C C G TG +C EI+ C S PC + GTC G+
Sbjct: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069
Query: 1047 -YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES---QCLCPSGWAGAYCDVPN 1102
+ C CP G+ G C C C + G C+ +C C SG+ G C P
Sbjct: 1070 GFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP- 1128
Query: 1103 VSCDIAASRRGVLVEHLCQHSGVCIN----AGNTHYCQCPLGYTGSYCEE 1148
+ +G C ++G C G C CP G C++
Sbjct: 1129 ------PAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQK 1172
Score = 290 bits (741), Expect = 2e-77
Identities = 195/602 (32%), Positives = 241/602 (40%), Gaps = 75/602 (12%)
Query: 28 CRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLG 86
C G PC+N G C G YC CP G CQ D C C NGGTCV + G
Sbjct: 733 CHSG--PCLNGGSCNPSPGGY-YCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRP--G 787
Query: 87 KATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT- 145
+C CA GF G C+ C S PC N TC S C C G+TG CQ
Sbjct: 788 TFSCLCAMGFQGPRCEGKLRPSCADS-PCRNRATCQD-SPQGPRCLCPTGYTGGSCQTLM 845
Query: 146 DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNEC---------DIPGHCQHGG 196
D C PC S C F C CL G+TG C ++ C D+ C +GG
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 197 TCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGST 256
C++ SY C CP GF G C PC PC NG TC + C C PG++G
Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPS-GYLCQCAPGYDGQN 964
Query: 257 CERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGT-- 314
C + +D C + C N G C ++C CPP + G C DVDECL QP C GT
Sbjct: 965 CSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQP--CHPTGTAA 1022
Query: 315 CANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVAS---FSCMCPEGKAGL 371
C + + C C+ G +G C ID C C G TC S F C CP+G G
Sbjct: 1023 CHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGP 1082
Query: 372 LC-HLDDACISNPCHKGALCDTNPLNG-QYICTCPQGYKGADCTEDVDECAMANSNPCEH 429
C H +C + CH G LC +P G C C GY G DC +PC +
Sbjct: 1083 TCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLY 1142
Query: 430 AGKCVNTDG----AFHCECLKGYAGPRCEM-DINECHSDPCQNDATCLDKIGGFTCLCMP 484
G C T G F C C GPRC+ C D C G P
Sbjct: 1143 NGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGR--SGDGACDAGCSG------P 1194
Query: 485 G--FKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCL 542
G + G C L + + C ++ +C QC C S CL
Sbjct: 1195 GGNWDGGDCSLGVPDPWKG-CPSHSRCWLLFRDGQC--------------HPQCDSEECL 1239
Query: 543 NGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGA 602
+GY+C+ T C D D H+G C+ G ++ C G+ G
Sbjct: 1240 F--------DGYDCE-----TPPACTPAYDQYCHDHFHNGHCEKGCNTAEC----GWDGG 1282
Query: 603 IC 604
C
Sbjct: 1283 DC 1284
Score = 154 bits (389), Expect = 1e-36
Identities = 106/368 (28%), Positives = 145/368 (39%), Gaps = 64/368 (17%)
Query: 1194 QPCQNGGTCIDL-VNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRI------- 1245
+PC NGGTC+ L + C C PG G C+ D C C NGG C +
Sbjct: 33 EPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLP 91
Query: 1246 -------GGYSCRCLPGFAGERCEGDINE-CLSNPCSSEGSLDCIQLTNDYLCVCRSAFT 1297
+ C CLPGF GERC+ + + C + CS G IQ + C C +T
Sbjct: 92 SSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCH-IQASGRPQCSCMPGWT 150
Query: 1298 GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQV-----KCR 1352
G C+ D C PC+NGG C C CPPGF G C+ + C
Sbjct: 151 GEQCQ-LRDFCSANPCVNGGVCLATYPQ---IQCHCPPGFEGHACERDVNECFQDPGPCP 206
Query: 1353 KGEQCVHTASGPRCFCP----SPRDCE---SGCASSPCQHGGSCH--PQRQPPYYSCQCA 1403
KG C +T +C CP PR CE C C +GG+C P++ ++ C C
Sbjct: 207 KGTSCHNTLGSFQCLCPVGQEGPR-CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP 265
Query: 1404 PPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHAC----QWDGGDCSLTM 1459
P F G CE+ P C+S C + G C + +++ C W G DCS +
Sbjct: 266 PGFIGPDCEV-------NPDNCVSHQCQN---GGTCQDGLDTYTCLCPETWTGWDCSEDV 315
Query: 1460 ENPWANCSSPLPCWDYINNQCDELCNTVECL----FDNFECQGN-----SKTCKYDKYCA 1510
+ C + P C + C+ + C+ N + TC C
Sbjct: 316 D----ECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI 371
Query: 1511 DHFKDNHC 1518
D C
Sbjct: 372 DRVGSFSC 379
Score = 38.1 bits (87), Expect = 0.11
Identities = 45/171 (26%), Positives = 56/171 (32%), Gaps = 46/171 (26%)
Query: 1371 PRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYC 1430
PR G PC +GG+C +CQCAP F G C+ P C
Sbjct: 23 PRGLLCGSFPEPCANGGTC-LSLSLGQGTCQCAPGFLGETCQF--------PDPCQ---- 69
Query: 1431 ADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECL 1490
N+ CQ +GG C + P SSP P LC CL
Sbjct: 70 -------------NAQLCQ-NGGSCQALLPAPLGLPSSPSPLTPSF------LCT---CL 106
Query: 1491 --FDNFECQGNSKTCKYDKYCADHFKDNHCD-QGCNSEEC----GWDGLDC 1534
F CQ + +C+ K C Q +C GW G C
Sbjct: 107 PGFTGERCQAKLEDPCPPSFCS---KRGRCHIQASGRPQCSCMPGWTGEQC 154
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 593 bits (1528), Expect = e-169
Identities = 349/1080 (32%), Positives = 486/1080 (45%), Gaps = 104/1080 (9%)
Query: 347 CTPGSTCIDRVAS--FSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQ---YIC 401
C+ C+ S +SC C +G C DAC PC C N Y C
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
Query: 402 TCPQGYKGADCTEDVDECAMANSNPCEHAGKCVN-TDGAFHCECLKGYAGPRCEMDINEC 460
C + G +C+E + +C + C H G C N T +F CEC + ++GP CE+ C
Sbjct: 243 VCHPPFTGKNCSEIIGQC---QPHVCFH-GNCSNITSNSFICECDEQFSGPFCEVSAKPC 298
Query: 461 HSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLC 520
S C + +T C G + E +++E PC N C+ N C+C
Sbjct: 299 VSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCIC 358
Query: 521 PPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCD----- 575
P FT +C+ C S P N A C Y C C +GFT CE+ ID+C
Sbjct: 359 SPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN 418
Query: 576 -----------------------PDPCHHGQCQDGIDSYTCICNPGYMGAICSD----QI 608
+PC + I + C C + G IC D Q
Sbjct: 419 CLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHG-ICQDKGPAQF 477
Query: 609 DECYSSPCLNDG--RCIDLVNGY---QCNCQPGTSGVNC-EINFDDC------ASNPCIH 656
+ + +C +++ Y NC + VN E N C C +
Sbjct: 478 EYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICAN 537
Query: 657 GI-CM--DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPH 713
G C+ + Y +C + G + + N C+ A C + +N RC C
Sbjct: 538 GCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYI 597
Query: 714 HPSCYSQVNECLSNPCI--HGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGT 771
C V+ CL N I HG C C + CE+D +C S C+NG T
Sbjct: 598 GRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTT 657
Query: 772 CDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLP------- 824
+L + C GFKG C+++IDECAS+PC N TC D Y C CV P
Sbjct: 658 STHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGF 717
Query: 825 -------YTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC 877
Y G C+ + C N CE+ + CK+ SY C+C W+G C + +EC
Sbjct: 718 SCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDL--HLSYQCVCLSDWEGNFCEQESNEC 775
Query: 878 ISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGV--NTFSC 935
PC N+ C + SY CEC G++G +C E+I++C ++PC NGG C + F C
Sbjct: 776 KMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVC 835
Query: 936 LCLPGFTGDKCQTDMNEC--LSEPCKNGGTCSDYVNSYT-CKCQAGFDGVHCENNINECT 992
LC P +TG C N C L PC+N TC V++ C C+ F+G +CE ++ +C
Sbjct: 836 LCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCL 895
Query: 993 ESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCP 1052
SC + G C D +N+F C+C GF+GS C EINECSS PC N GTCVD + C+C
Sbjct: 896 FLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCE 955
Query: 1053 LGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRR 1112
Y G C+ VN C SPC ++ CV + CLC G+ G C++ C
Sbjct: 956 PEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDEC------- 1008
Query: 1113 GVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYR 1172
+ C H GVCI+ N + C C G+ G++CE ++C SNPC HG C++ I Y
Sbjct: 1009 ---LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGR-CTELINEYP 1064
Query: 1173 CECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCAR- 1231
C C C+ ++++C + PC N G C + F C CP G G CE++ID+CA
Sbjct: 1065 CSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEP 1124
Query: 1232 ---GPHCLNGGQCMDRIGG-YSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTND 1287
CLNGG C+D G + CRCLPGF+G+ CE +INEC S+PC DC N
Sbjct: 1125 ELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLH--GADCEDHING 1182
Query: 1288 YLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCG 1347
Y+C C+ ++G HCE ++ P N + G C C PGF CG
Sbjct: 1183 YVCKCQPGWSGHHCENELECIP-----NSCVHELCMENEPGSTCLCTPGFMTCSIGLLCG 1237
Score = 593 bits (1528), Expect = e-169
Identities = 344/1096 (31%), Positives = 495/1096 (45%), Gaps = 159/1096 (14%)
Query: 269 CQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG----- 321
C G C+ TY+C C P ++G++C E +D C +P C+N G+C N+
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-LDACSFKP--CKNNGSCINKRENWDEQA 239
Query: 322 YGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DACI 380
Y CVC ++G +CSE I C C G+ SF C C E +G C + C+
Sbjct: 240 YECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCV 299
Query: 381 SNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAF 440
S K +C + + Y CP+G + DV E ++ PC++ C+
Sbjct: 300 SLLFWKRGICPNS--SSAYTYECPKGSSSQNGETDVSEFSLV---PCQNGTDCIKISNDV 354
Query: 441 HCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINE--- 497
C C + C+ C S P +N+ATC + C C+ GF +CE I+
Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKL 414
Query: 498 -------------------------CQSNPC------------------VNNGQCVDK-V 513
C NPC +G C DK
Sbjct: 415 LSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGP 474
Query: 514 NRFQCLCPPGFTGPV---CQIDID-------DCSSTP----------------------- 540
+F+ + GF G CQ ID +C+
Sbjct: 475 AQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEI 534
Query: 541 CLNGAKCIDHPNGYECQ--CATGFTGVLCEENIDNCDPDPCHH-GQCQDGIDSYTCICNP 597
C NG C+ + E + C + G + EN + + C H C+D I+ C C+
Sbjct: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSL 594
Query: 598 GYMGAICSDQIDECYSSPCLN-DGRCIDLVNGYQCNCQPGTSGVN------CEINFDDCA 650
Y+G +C +D C + ++ G C+ L + CNC SG+ CEI+ +DC
Sbjct: 595 SYIGRLCVVNVDYCLGNHSISVHGLCLAL--SHNCNC----SGLQRYERNICEIDTEDCK 648
Query: 651 SNPCIHGICMDGINRYSC-VCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICP 709
S C +G + Y C PGF G +C IDIDECAS+PC+ GATCI+ + C C
Sbjct: 649 SASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCV 708
Query: 710 EGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNG 769
+ V+ G+ CLC+ G+VGI CE D ++C+ N C++
Sbjct: 709 PP------FKVVD-----------------GFSCLCNPGYVGIRCEQDIDDCILNACEHN 745
Query: 770 GTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKN 829
TC +L Y+C C ++G C+ +EC NPC N TC D Y C C +TG+N
Sbjct: 746 STCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQN 805
Query: 830 CQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC--ISKPCMNHGL 887
C + C +PC N +C ES + CLC P + GQ C + C + PC N+
Sbjct: 806 CSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNST 865
Query: 888 CHN-TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKC 946
C + C C F G +CE D+ DCL CQ+ G C D VN F C+C PGF+G C
Sbjct: 866 CLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLC 925
Query: 947 QTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGI 1006
+ ++NEC SEPCKN GTC D N + C C+ + G CE ++N+C S C + CV
Sbjct: 926 EIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRT 985
Query: 1007 NSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNL 1066
+ ++CLC G+TG C ++EC S PCL++G C+DG+ Y C C G+ G +C+T N
Sbjct: 986 DGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNAND 1045
Query: 1067 CSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVC 1126
C +PC + G C + E C C + C + C C + G C
Sbjct: 1046 CLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIP----------CMNEGFC 1094
Query: 1127 INAGNTHYCQCPLGYTGSYCEEQLDECA-----SNPCQHGATCSDFIG-GYRCECVPGYQ 1180
+ + C CP GYTG+YCE+ +D CA S C +G C D G + C C+PG+
Sbjct: 1095 QKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFS 1154
Query: 1181 GVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQ 1240
G CE ++EC + PC +G C D +N + C C PG G CE + +C P+
Sbjct: 1155 GQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL-ECI--PNSCVHEL 1211
Query: 1241 CMDRIGGYSCRCLPGF 1256
CM+ G +C C PGF
Sbjct: 1212 CMENEPGSTCLCTPGF 1227
Score = 582 bits (1499), Expect = e-165
Identities = 343/1100 (31%), Positives = 512/1100 (46%), Gaps = 150/1100 (13%)
Query: 31 GYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKA-- 88
G+ C++E TY C C F G+YCQ D C C+N G+C+ +
Sbjct: 185 GHGKCLSEAWSKTYS-----CHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQA 239
Query: 89 -TCRCASGFTGEDCQ----YSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ 143
C C FTG++C H CF G C ++ +++ C C F+G C+
Sbjct: 240 YECVCHPPFTGKNCSEIIGQCQPHVCF-------HGNCSNITSNSFICECDEQFSGPFCE 292
Query: 144 WT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLP 202
+ C+S C ++ ++ +C G + Q ETDV+E + CQ+G C+ +
Sbjct: 293 VSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLV-PCQNGTDCIKIS 351
Query: 203 GSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNID 262
C C FT C S+ C P N TC++ + + C+C+ GF CE+ ID
Sbjct: 352 NDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKC-EKDYPCSCISGFTEKNCEKAID 410
Query: 263 DCP--NHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNG----GTCA 316
C + C N C + + + C P T C + L+ + C G G C
Sbjct: 411 HCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQ 470
Query: 317 NRN-GGYGCVCVNGWSGDD---CSENIDDCAF--ASCTPGSTCID--RVASFSCMCPEGK 368
++ + V G++G + C ID F A+CT +T ++ + SC P
Sbjct: 471 DKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEG 530
Query: 369 AGLLCHLDDACIS-----------------------------NPCHKGALCDTNPLNGQY 399
+C +C+S N C A+C + +N +
Sbjct: 531 TKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVC-KDEIN-RP 588
Query: 400 ICTCPQGYKGADCTEDVDEC-----------AMANSNPCEHAG----------------- 431
C+C Y G C +VD C +A S+ C +G
Sbjct: 589 RCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCK 648
Query: 432 --KCVN------TDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIG------- 476
C N G F +C+ G+ G +CE+DI+EC S PC+N ATC+D+ G
Sbjct: 649 SASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCV 708
Query: 477 -------GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVC 529
GF+CLC PG+ G+ CE +I++C N C +N C D +QC+C + G C
Sbjct: 709 PPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFC 768
Query: 530 QIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPC-HHGQCQDGI 588
+ + ++C PC N + C D Y C+C +G+TG C E I+ CD DPC + G C +
Sbjct: 769 EQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHEST 828
Query: 589 --DSYTCICNPGYMGAICSDQIDEC--YSSPCLNDGRCIDLVNGYQ-CNCQPGTSGVNCE 643
+ C+C P Y G C + + C +PC N+ C+ LV+ Q C C+ G NCE
Sbjct: 829 IPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE 888
Query: 644 INFDDCASNPC-IHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVN 702
I+ DC C +G C D +N + C+C PGF+G C I+I+EC+S PC+ TC++ N
Sbjct: 889 IDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTN 948
Query: 703 GFRCICPEGPHHPSCYSQVNECLSNPCI-HGNCTGGLSGYKCLCDAGWVGINCEVDKNEC 761
F C C H P C VN+C +PC+ NC GY CLC G+ GINCE++ +EC
Sbjct: 949 RFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDEC 1008
Query: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHC 821
LS PC + G C + +N Y C CK GF G +C+ N ++C SNPCL+ G C + I+ Y C C
Sbjct: 1009 LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSC 1067
Query: 822 VLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECI--- 878
T C+ + C+ PC N C++S + +TC+C G+ G C ID C
Sbjct: 1068 DADGTSTQCKIKINDCTSIPCMNEGFCQKSAH--GFTCICPRGYTGAYCEKSIDNCAEPE 1125
Query: 879 --SKPCMNHGLCHNTQG-SYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSC 935
S C+N G+C + G ++ C C PGFSG CE +I++C ++PC +G C D +N + C
Sbjct: 1126 LNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVC 1185
Query: 936 LCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESS 995
C PG++G C+ ++ EC+ C + C + TC C GF +
Sbjct: 1186 KCQPGWSGHHCENEL-ECIPNSCVH-ELCMENEPGSTCLCTPGF--------------MT 1229
Query: 996 CFNGGTCVDGINSFSCLCPV 1015
C G C D I +CL P+
Sbjct: 1230 CSIGLLCGDEIRRITCLTPI 1249
Score = 561 bits (1445), Expect = e-159
Identities = 341/1084 (31%), Positives = 482/1084 (44%), Gaps = 175/1084 (16%)
Query: 101 CQYSTSHPCFVSRPCLNGGTCHMLS-RDTYECTCQVGFTGKECQWTDACLSHPCANGSTC 159
CQ S S S C G C + TY C CQ F+GK CQ DAC PC N +C
Sbjct: 174 CQESLS-----SEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSC 228
Query: 160 TTVANQ-----FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214
+ C C FTG+ C + +C P C HG S+ C+C + F+
Sbjct: 229 INKRENWDEQAYECVCHPPFTGKNCSEIIGQCQ-PHVCFHGNCSNITSNSFICECDEQFS 287
Query: 215 GQYCDSLYVPCAPSPCVNGGTC-RQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGG 273
G +C+ PC G C + +T+EC G E ++ + CQNG
Sbjct: 288 GPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECP--KGSSSQNGETDVSEFSLVPCQNGT 345
Query: 274 VCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD 333
C+ N C C P +T C C P +N TC Y C C++G++
Sbjct: 346 DCIKISNDVMCICSPIFTDLLCKSIQTSCESFP--LRNNATCKKCEKDYPCSCISGFTEK 403
Query: 334 DCSENIDDCAFAS--CTPGSTCIDRVASFSCMCPEG---------KAGLLCHLDDACISN 382
+C + ID C S C C + + F +C G K L H C
Sbjct: 404 NCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIH-QHLCYCG 462
Query: 383 PCHKGALCDTNPLNGQYICTCP---------QG------YKGADCTED---VDECAMANS 424
G D P +Y+ QG + A+CTED V++ NS
Sbjct: 463 VTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNS 522
Query: 425 N----------PCEHAGKCVNTDGA--FHCECLKGYAGPRCEMDINECHSDPCQNDATCL 472
+ C + C++ + + + C +AG + + + CQ++A C
Sbjct: 523 SCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCK 582
Query: 473 DKIGGFTCLCMPGFKG-----------------VH----------------------CEL 493
D+I C C + G VH CE+
Sbjct: 583 DEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEI 642
Query: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNG 553
+ +C+S C N F C PGF G C+IDID+C+S PC NGA CID P
Sbjct: 643 DTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGN 702
Query: 554 YECQCA--------------TGFTGVLCEENIDNCDPDPC-HHGQCQDGIDSYTCICNPG 598
Y CQC G+ G+ CE++ID+C + C H+ C+D SY C+C
Sbjct: 703 YFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSD 762
Query: 599 YMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIH-G 657
+ G C + +EC +PC N+ C DL Y+C C G +G NC ++C S+PC++ G
Sbjct: 763 WEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGG 822
Query: 658 ICMDGI--NRYSCVCSPGFTGQRCNIDIDEC--ASNPCRKGATCINGVNGFR-CICPEGP 712
+C + ++ C+C P +TGQ C+ + C NPCR +TC+ V+ + CIC E
Sbjct: 823 LCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEF 882
Query: 713 HHPSCYSQVNECLSNPC-IHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGT 771
+C V +CL C +G+C ++ ++C+C G+ G CE++ NEC S PC+N GT
Sbjct: 883 EGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGT 942
Query: 772 CDNLVN--------------------------------------GYRCTCKKGFKGYNCQ 793
C +L N GY C C G+ G NC+
Sbjct: 943 CVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCE 1002
Query: 794 VNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPN 853
+N+DEC S PCL+ G C D I+ YTC C + G +C+T C NPC + C E N
Sbjct: 1003 INLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGR-CTELIN 1061
Query: 854 FESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDID 913
Y C C +C I I++C S PCMN G C + + C CP G++G CE+ ID
Sbjct: 1062 --EYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSID 1119
Query: 914 DCLANP------CQNGGSCMDGV-NTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSD 966
+C A P C NGG C+DG +TF C CLPGF+G C+ ++NEC S PC +G C D
Sbjct: 1120 NC-AEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCED 1178
Query: 967 YVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFC 1022
++N Y CKCQ G+ G HCEN + EC +SC + C++ +CLC GF G C
Sbjct: 1179 HINGYVCKCQPGWSGHHCENEL-ECIPNSCVH-ELCMENEPGSTCLCTPGFMTCSIGLLC 1236
Query: 1023 LHEI 1026
EI
Sbjct: 1237 GDEI 1240
Score = 537 bits (1383), Expect = e-152
Identities = 340/1109 (30%), Positives = 485/1109 (43%), Gaps = 139/1109 (12%)
Query: 503 CVNNGQCVDKV--NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDH-----PNGYE 555
C +G+C+ + + C C P F+G CQ ++D CS PC N CI+ YE
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYE 241
Query: 556 CQCATGFTGVLCEENIDNCDPDPCHHGQCQD-GIDSYTCICNPGYMGAICSDQIDECYSS 614
C C FTG C E I C P C HG C + +S+ C C+ + G C C S
Sbjct: 242 CVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL 301
Query: 615 PCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCVCSPG 673
G C + + Y C G+S N E + + + PC +G C+ N C+CSP
Sbjct: 302 LFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPI 361
Query: 674 FTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNEC--LSNPCIH 731
FT C C S P R ATC + C C G +C ++ C LS C++
Sbjct: 362 FTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLN 421
Query: 732 GN-CTGGLSGYKCLCDAGWVGINCEVDKNECLSNP--CQNGGTCDNLVNG-----YRCTC 783
C + +K +C G C KN L + C G T + +
Sbjct: 422 EEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVW 481
Query: 784 KKGF---KGYNCQVNID------------------------------ECASNPCLNQGTC 810
+ GF +G CQ ID E C N +C
Sbjct: 482 QLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSC 541
Query: 811 F--DDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ 868
+D Y C L + G N C++ AVCK+ N C C+ + G+
Sbjct: 542 LSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPR--CSCSLSYIGR 599
Query: 869 RCTIDIDECISKPCMN-HGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCM 927
C +++D C+ ++ HGLC + C + CE D +DC + C+NG +
Sbjct: 600 LCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTST 659
Query: 928 DGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDY--------------VNSYTC 973
F C+PGF G +C+ D++EC S PCKNG TC D V+ ++C
Sbjct: 660 HLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSC 719
Query: 974 KCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHP 1033
C G+ G+ CE +I++C ++C + TC D S+ C+C + G+FC E NEC +P
Sbjct: 720 LCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNP 779
Query: 1034 CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQ--CLCPS 1091
C N TC D +YRC C G+TG+NC +N C PC N G C + Q CLCP
Sbjct: 780 CKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPP 839
Query: 1092 GWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTH-YCQCPLGYTGSYCEEQL 1150
+ G +C CD L+ + C+++ C+ + + +C C + G CE +
Sbjct: 840 LYTGQFCHQRYNLCD--------LLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDV 891
Query: 1151 DECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210
+C CQ C D + +RC C PG+ G CE E++EC ++PC+N GTC+DL N F
Sbjct: 892 KDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFF 951
Query: 1211 CSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLS 1270
C+C P G CE +++ C P CL+ C+ R GY+C C PG+ G CE +++ECLS
Sbjct: 952 CNCEPEYHGPFCELDVNKCKISP-CLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLS 1010
Query: 1271 NPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFI 1330
PC +G CI N Y C C+S F G HCET + C PCL+G + + P
Sbjct: 1011 EPCLHDGV--CIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYP---- 1064
Query: 1331 CRCPPGFSGARCQ---SSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCESG---CA-- 1379
C C + +C+ + C + C C +A G C CP + CE CA
Sbjct: 1065 CSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEP 1124
Query: 1380 ---SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARD 1436
S C +GG C + C+C P FSG CE+ S+ P CL + AD
Sbjct: 1125 ELNSVICLNGGIC-VDGPGHTFDCRCLPGFSGQFCEININECSSSP--CL--HGAD---- 1175
Query: 1437 GVCDEACNSHACQWDGGDCSLTMENPWA--NCSSPLPCWDYINNQC-DELCNTVE----C 1489
C++ N + C+ G W+ +C + L C I N C ELC E C
Sbjct: 1176 --CEDHINGYVCKCQPG---------WSGHHCENELEC---IPNSCVHELCMENEPGSTC 1221
Query: 1490 LFDNFECQGNSKTCKYDKYCADHFKDNHC 1518
L C TC C D + C
Sbjct: 1222 L-----CTPGFMTCSIGLLCGDEIRRITC 1245
Score = 532 bits (1370), Expect = e-150
Identities = 316/1056 (29%), Positives = 456/1056 (43%), Gaps = 165/1056 (15%)
Query: 192 CQHGGTCLNLPGS--YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTC---RQTGDF-TFE 245
C G CL+ S Y C C F+G+YC L C+ PC N G+C R+ D +E
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDA-CSFKPCKNNGSCINKRENWDEQAYE 241
Query: 246 CNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQ 305
C C P F G C I C H C +G N++ C C Q++G FC C+
Sbjct: 242 CVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCV-- 299
Query: 306 PNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCP 365
G C N + Y C G S + ++ + + C G+ CI C+C
Sbjct: 300 SLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICS 359
Query: 366 EGKAGLLC-HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANS 424
LLC + +C S P A C Y C+C G+ +C + +D C + +
Sbjct: 360 PIFTDLLCKSIQTSCESFPLRNNATC--KKCEKDYPCSCISGFTEKNCEKAIDHCKLLSI 417
Query: 425 NPCEHAGKCVNTDGAFHCECLKGYAGPRCEM--DINECHSDPCQNDAT----CLDK-IGG 477
N C + C N G F C+ G C ++ H C T C DK
Sbjct: 418 N-CLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQ 476
Query: 478 FTCLCMPGFKGVHCE--------------------LEINECQSNP-------------CV 504
F + GF G E +N+ + N C
Sbjct: 477 FEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICA 536
Query: 505 NNGQCVDKVN--RFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF 562
N C+ + + ++ LC + G + + D C + A C D N C C+ +
Sbjct: 537 NGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSY 596
Query: 563 TGVLCEENIDNC----------------------------------DPDPCHHGQCQDGI 588
G LC N+D C D + C C++G
Sbjct: 597 IGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGT 656
Query: 589 DS------YTCICNPGYMGAICSDQIDECYSSPCLNDGRCID--------------LVNG 628
S + C PG+ G C IDEC S PC N CID +V+G
Sbjct: 657 TSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDG 716
Query: 629 YQCNCQPGTSGVNCEINFDDCASNPCIH-GICMDGINRYSCVCSPGFTGQRCNIDIDECA 687
+ C C PG G+ CE + DDC N C H C D Y CVC + G C + +EC
Sbjct: 717 FSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECK 776
Query: 688 SNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNC------------- 734
NPC+ +TC + +RC C G +C ++NEC S+PC++G
Sbjct: 777 MNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCL 836
Query: 735 -----TGGL--------------------------SGYKCLCDAGWVGINCEVDKNECLS 763
TG + C+C + G NCE+D +CL
Sbjct: 837 CPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLF 896
Query: 764 NPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVL 823
CQ+ G C+++VN +RC C+ GF G C++ I+EC+S PC N GTC D + + C+C
Sbjct: 897 LSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEP 956
Query: 824 PYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCM 883
Y G C+ + C +PC + C + Y CLCAPG+ G C I++DEC+S+PC+
Sbjct: 957 EYHGPFCELDVNKCKISPCLDEENCVY--RTDGYNCLCAPGYTGINCEINLDECLSEPCL 1014
Query: 884 NHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTG 943
+ G+C + Y C+C GF G CE + +DCL+NPC + G C + +N + C C T
Sbjct: 1015 HDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSCDADGTS 1073
Query: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESS-----CFN 998
+C+ +N+C S PC N G C + +TC C G+ G +CE +I+ C E C N
Sbjct: 1074 TQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLN 1133
Query: 999 GGTCVDGI-NSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTG 1057
GG CVDG ++F C C GF+G FC INECSS PCL+ C D + Y C C G++G
Sbjct: 1134 GGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSG 1193
Query: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093
+C+ + C + C ++ C++ + S CLC G+
Sbjct: 1194 HHCENELE-CIPNSCVHE-LCMENEPGSTCLCTPGF 1227
Score = 367 bits (942), Expect = e-101
Identities = 267/1013 (26%), Positives = 397/1013 (39%), Gaps = 181/1013 (17%)
Query: 656 HGICMDGI--NRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPH 713
HG C+ YSC C P F+G+ C ++D C+ PC+ +CIN +
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENW--------- 235
Query: 714 HPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCD 773
Y+C+C + G NC +C + C +G +
Sbjct: 236 -----------------------DEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSN 272
Query: 774 NLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTV 833
N + C C + F G C+V+ C S +G C + S YT C + +N +T
Sbjct: 273 ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETD 332
Query: 834 LAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQG 893
++ S PC+N C + N C+C+P + C C S P N+ C +
Sbjct: 333 VSEFSLVPCQNGTDCIKISN--DVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEK 390
Query: 894 SYMCECPPGFSGMDCEEDIDDC--LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMN 951
Y C C GF+ +CE+ ID C L+ C N C + + F +C+PG T + C N
Sbjct: 391 DYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKN 450
Query: 952 ECLSEP--CKNG----GTCSD-------------YVNSYTCKCQAGFDG-----VHC--- 984
L C G G C D + S KCQ D +C
Sbjct: 451 VYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTED 510
Query: 985 -------ENNINEC------TESSCFNGGTCVDGINS--FSCLCPVGFTGSFCLHEINEC 1029
E+N + C T+ C NG +C+ +S + LC + + G+ L +
Sbjct: 511 ATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDD 570
Query: 1030 SSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLC-SRSPCKNKGTCVQKKAESQCL 1088
+ C +E C D + RCSC L Y G+ C V+ C G C+ C
Sbjct: 571 QENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCS 630
Query: 1089 CPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEE 1148
+ C++ C A+ + G HL + + +C G+ G+ CE
Sbjct: 631 GLQRYERNICEIDTEDCKSASCKNGTTSTHLRGY----------FFRKCVPGFKGTQCEI 680
Query: 1149 QLDECASNPCQHGATCSDFIGGYRCECVP--------------GYQGVNCEYEVDECQNQ 1194
+DECAS+PC++GATC D G Y C+CVP GY G+ CE ++D+C
Sbjct: 681 DIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILN 740
Query: 1195 PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLP 1254
C++ TC DL ++C C G CE+ ++C P C N C D Y C C
Sbjct: 741 ACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNP-CKNNSTCTDLYKSYRCECTS 799
Query: 1255 GFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQM--P 1312
G+ G+ C +INEC S+PC + G + ++C+C +TG+ C ++C + P
Sbjct: 800 GWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNP 859
Query: 1313 CLNGGTCAV------------------------------------ASNMPDGFICRCPPG 1336
C N TC +M + F C C PG
Sbjct: 860 CRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPG 919
Query: 1337 FSGARCQ---SSCGQVKCRKGEQCVHTASGPRCFCPSPRD---CE---SGCASSPCQHGG 1387
FSG+ C+ + C C+ CV + C C CE + C SPC
Sbjct: 920 FSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEE 979
Query: 1388 SCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHA 1447
+C + Y+C CAP ++G CE+ CLS+ C DGVC + N +
Sbjct: 980 NC--VYRTDGYNCLCAPGYTGINCEINL-------DECLSEPC---LHDGVCIDGINHYT 1027
Query: 1448 CQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKY-- 1505
C G E +C S PC ++ +C EL N C D G S CK
Sbjct: 1028 CDCKSGFFGTHCETNANDCLSN-PC---LHGRCTELINEYPCSCD---ADGTSTQCKIKI 1080
Query: 1506 -DKYCADHFKDNHCDQGCNSEEC----GWDGLDCAADQPENLAEGTLVIVVLM 1553
D + C + + C G+ G C +N AE L V+ +
Sbjct: 1081 NDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYC-EKSIDNCAEPELNSVICL 1132
Score = 94.4 bits (233), Expect = 1e-18
Identities = 95/350 (27%), Positives = 145/350 (41%), Gaps = 52/350 (14%)
Query: 991 CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECS-----SHPCLNEGTCVDGLG 1045
C+ C NGGTC++ S C C G+ GSFC ++ C H C TC+
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 1046 TYRCSCPLGYTGKNCQTLVNLCSRSPCKNK-------GTCVQKKA----ESQCLCPSG-- 1092
Y C CPLG TG C+ +++ S N+ V+KK + Q L G
Sbjct: 2674 GYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGIL 2733
Query: 1093 ---------WAGAYCDVPNVSCDIA----ASRRGVLVEHLCQHSGVCINAGNTHYCQCPL 1139
+G + + V+ + R +++E L V IN H +
Sbjct: 2734 FYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETL---QKVTINGSTWHIIKA-- 2788
Query: 1140 GYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNG 1199
G G+ E LD N + +T + + G +N + +N+P
Sbjct: 2789 GRVGA--EGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPM-AIENEPVGFQ 2845
Query: 1200 GTCID--LVNHFKCSCPP-GTRGLLCEENIDDC---ARGPH-CLNGGQCMDRIGGYSCRC 1252
G CI ++N+ + G +G N+ DC A G + C NGG+C +SCRC
Sbjct: 2846 G-CIRQVIINNQELQLTEFGAKG---GSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRC 2901
Query: 1253 LPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
LP +AG C ++ CL+N C + SL + Y C+C + GR+CE
Sbjct: 2902 LPDWAGNTCNQSVS-CLNNLCLHQ-SLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 84.0 bits (206), Expect = 2e-15
Identities = 91/374 (24%), Positives = 140/374 (37%), Gaps = 48/374 (12%)
Query: 877 CISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNT-FSC 935
C C N+G C + + CECP +SG C+ C NPC NG +C+ T C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
Query: 936 LCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCE--------NN 987
LC G +G C +N +++P +G Y S+ + H E NN
Sbjct: 2397 LCPYGRSGPLCTDAIN--ITQPRFSGTDAFGY-TSFLAYSRISDISFHYEFHLKFQLANN 2453
Query: 988 INECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTY 1047
+ + F G G+N L VG ++ N S + LG +
Sbjct: 2454 HSALQNNLIFFTGQKGHGLNGDDFLA-VGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVH 2512
Query: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCD-----VPN 1102
+ GK Q KNK + + + G Y + +PN
Sbjct: 2513 TV-----HLGKFFQE--GWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPN 2565
Query: 1103 VSCDIAASRRGVL--VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQ- 1159
D +G + ++ + G GN P G+ + + +C ++PC
Sbjct: 2566 -GADFKNGFQGCIFTLQVRTEKDGHFRGLGN------PEGHPNA--GRSVGQCHASPCSL 2616
Query: 1160 ----HGATCSDFIGGYRCECVPGYQGVNCEYEVDEC--QNQP---CQNGGTCIDLVNHFK 1210
+G TC + C C G++G C V C ++ P C G TCI L + +
Sbjct: 2617 MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYT 2676
Query: 1211 CSCPPGTRGLLCEE 1224
C CP GT G+ CE+
Sbjct: 2677 CFCPLGTTGIYCEQ 2690
Score = 78.2 bits (191), Expect = 9e-14
Identities = 88/380 (23%), Positives = 130/380 (34%), Gaps = 82/380 (21%)
Query: 824 PYTGKNC-QTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP- 881
P G++ Q +PCS C N C ES S C C GW+G CT + C +
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGT--SVYCNCTTGWKGSFCTETVSTCDPEHD 2657
Query: 882 ----CMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCM---------- 927
C C + Y C CP G +G+ CE+ + + N S M
Sbjct: 2658 PPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKK 2717
Query: 928 ------------DGVNTFSCLCLPGFTGDKC-----------------QTDMNECLSEPC 958
DG+ ++ L +GD +T + E L +
Sbjct: 2718 THIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVT 2777
Query: 959 KNGGTCSDY-VNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCP--- 1014
NG T + DG++ + S N + G++S + + P
Sbjct: 2778 INGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAI 2837
Query: 1015 ----VGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRS 1070
VGF G C+ ++ + L E G C C +
Sbjct: 2838 ENEPVGFQG--CIRQVIINNQELQLTEFGAKGGSNVGDCDG-------------TACGYN 2882
Query: 1071 PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130
C+N G C C C WAG C+ +VSC + +LC H +CI
Sbjct: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSC----------LNNLCLHQSLCIPDQ 2931
Query: 1131 NTHY-CQCPLGYTGSYCEEQ 1149
+ Y C C LG+ G YCE +
Sbjct: 2932 SFSYSCLCTLGWVGRYCENK 2951
Score = 73.6 bits (179), Expect = 2e-12
Identities = 34/85 (40%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI----PGHCQHGGTCLNLPG 203
C C NG TC C C TG+ G C V+ CD P HC G TC++LP
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 204 SYQCQCPQGFTGQYCDSLYVPCAPS 228
Y C CP G TG YC+ PS
Sbjct: 2674 GYTCFCPLGTTGIYCEQALSISDPS 2698
Score = 66.6 bits (161), Expect = 3e-10
Identities = 29/79 (36%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query: 224 PCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC-----PNHRCQNGGVCVDG 278
PC+ C NGGTC ++G + CNC G++GS C + C P H C G C+
Sbjct: 2613 PCSLMKCGNGGTCIESGTSVY-CNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
Query: 279 VNTYNCRCPPQWTGQFCTE 297
+ Y C CP TG +C +
Sbjct: 2672 PHGYTCFCPLGTTGIYCEQ 2690
Score = 65.9 bits (159), Expect = 5e-10
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 264 CPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQ---PNACQNGGTCANRNG 320
C +C NGG C++ + C C W G FCTE V C + P+ C G TC +
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 321 GYGCVCVNGWSGDDCSE--NIDDCAFAS 346
GY C C G +G C + +I D +F S
Sbjct: 2674 GYTCFCPLGTTGIYCEQALSISDPSFRS 2701
Score = 63.5 bits (153), Expect = 2e-09
Identities = 34/87 (39%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
Query: 907 DCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTC-S 965
DC D C N C+NGG C TFSC CLP + G+ C ++ CL+ C + C
Sbjct: 2873 DC--DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIP 2929
Query: 966 DYVNSYTCKCQAGFDGVHCENNINECT 992
D SY+C C G+ G +CEN + T
Sbjct: 2930 DQSFSYSCLCTLGWVGRYCENKTSFST 2956
Score = 63.2 bits (152), Expect = 3e-09
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 10/92 (10%)
Query: 495 INECQSNPCV-----NNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP-----CLNG 544
+ +C ++PC N G C++ C C G+ G C + C C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 545 AKCIDHPNGYECQCATGFTGVLCEENIDNCDP 576
A CI P+GY C C G TG+ CE+ + DP
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDP 2697
Score = 62.4 bits (150), Expect = 5e-09
Identities = 76/309 (24%), Positives = 110/309 (35%), Gaps = 81/309 (26%)
Query: 953 CLSEPCKNGGTC-----SDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVD--- 1004
C + C NGGTC S + S+ C C F G CE + S FNG + ++
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPS--FNGNSYLELPF 2160
Query: 1005 -----------GINSFSCLCPVGFTGSFCLHEINECSS---HPCLNEG--TCVDGLG--- 1045
+ + + G+ N C H L EG + G G
Sbjct: 2161 LKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQ 2220
Query: 1046 -------------------TYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCV----QKK 1082
T R + P+G G C + + P + K T + Q
Sbjct: 2221 NILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAY 2280
Query: 1083 AESQCL--CPS------------GWAGAYCDVPNVSCD---IAASRRGVLVE-------- 1117
ES L P+ G+ G D+ + + I +R G +E
Sbjct: 2281 FESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCA 2340
Query: 1118 -HLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIG-GYRCEC 1175
HLC+++G CI+ +C+CP Y+G C Q C +NPC +GATC G C C
Sbjct: 2341 HHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVCLC 2398
Query: 1176 VPGYQGVNC 1184
G G C
Sbjct: 2399 PYGRSGPLC 2407
Score = 61.6 bits (148), Expect = 9e-09
Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 5/79 (6%)
Query: 218 CDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCV- 276
CD C + C NGG C G TF C CLP + G+TC +++ C N+ C + +C+
Sbjct: 2874 CDG--TACGYNTCRNGGECTVNGT-TFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIP 2929
Query: 277 DGVNTYNCRCPPQWTGQFC 295
D +Y+C C W G++C
Sbjct: 2930 DQSFSYSCLCTLGWVGRYC 2948
Score = 60.5 bits (145), Expect = 2e-08
Identities = 88/395 (22%), Positives = 125/395 (31%), Gaps = 105/395 (26%)
Query: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
C C+N+ TC+ C C + G C+ C++NPC N CV
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCV--------- 2387
Query: 520 CPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPD-- 577
P T VC S P A I P + A G+T L I +
Sbjct: 2388 -PKSGTDIVCLCPYG--RSGPLCTDAINITQPR-FSGTDAFGYTSFLAYSRISDISFHYE 2443
Query: 578 -------PCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNG-- 628
+H Q+ + +T G G +D + L+NG
Sbjct: 2444 FHLKFQLANNHSALQNNLIFFTGQKGHGLNG----------------DDFLAVGLLNGSV 2487
Query: 629 -YQCNCQPGTSGVNCE---------------------INFDDCASNPCIHGICMDGINRY 666
Y N G + + E + DD + I + G+N +
Sbjct: 2488 VYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVF 2547
Query: 667 SCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCIC-----------------P 709
S G++ E + GA NG G CI P
Sbjct: 2548 SQFYVGGYS---------EYTPDLLPNGADFKNGFQG--CIFTLQVRTEKDGHFRGLGNP 2596
Query: 710 EGPHHPSCYSQVNECLSNPCI------HGNCTGGLSGYKCLCDAGWVGINCEVDKNEC-- 761
EG HP+ V +C ++PC G C + C C GW G C + C
Sbjct: 2597 EG--HPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDP 2654
Query: 762 ---LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ 793
+ C G TC +L +GY C C G G C+
Sbjct: 2655 EHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 60.1 bits (144), Expect = 3e-08
Identities = 31/87 (35%), Positives = 35/87 (40%), Gaps = 6/87 (6%)
Query: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP--DPCHH---- 581
V Q CS C NG CI+ C C TG+ G C E + CDP DP HH
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 582 GQCQDGIDSYTCICNPGYMGAICSDQI 608
C YTC C G G C +
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCEQAL 2692
Score = 59.7 bits (143), Expect = 3e-08
Identities = 33/81 (40%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 791 NCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKE 850
NC V CA + C N GTC D C C Y+GK CQ A C NPC N A C
Sbjct: 2333 NCHV--PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVP 2388
Query: 851 SPNFESYTCLCAPGWQGQRCT 871
+ CLC G G CT
Sbjct: 2389 KSGTD-IVCLCPYGRSGPLCT 2408
Score = 59.7 bits (143), Expect = 3e-08
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
Query: 299 VDECLLQPNA---CQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFAS-----CTPG 350
V +C P + C NGGTC C C GW G C+E + C C+ G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 351 STCIDRVASFSCMCPEGKAGLLC 373
+TCI ++C CP G G+ C
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYC 2688
Score = 58.9 bits (141), Expect = 6e-08
Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 260 NIDDCPN-----HRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGT 314
N+ DC + C+NGG C T++CRC P W G C + V CL N C +
Sbjct: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCL--NNLCLHQSL 2926
Query: 315 C-ANRNGGYGCVCVNGWSGDDC 335
C +++ Y C+C GW G C
Sbjct: 2927 CIPDQSFSYSCLCTLGWVGRYC 2948
Score = 58.5 bits (140), Expect = 8e-08
Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 981 GVHCEN-NINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGT 1039
G + EN ++ C C N GTC+ + C CP ++G C + C ++PC N T
Sbjct: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGAT 2385
Query: 1040 CVDGLGT-YRCSCPLGYTGKNCQTLVNL 1066
CV GT C CP G +G C +N+
Sbjct: 2386 CVPKSGTDIVCLCPYGRSGPLCTDAINI 2413
Score = 57.8 bits (138), Expect = 1e-07
Identities = 31/89 (34%), Positives = 38/89 (42%), Gaps = 9/89 (10%)
Query: 1183 NCEYEVDECQNQPCQ-----NGGTCIDLVNHFKCSCPPGTRGLLCEENIDDC--ARGP-- 1233
N V +C PC NGGTCI+ C+C G +G C E + C P
Sbjct: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
Query: 1234 HCLNGGQCMDRIGGYSCRCLPGFAGERCE 1262
HC G C+ GY+C C G G CE
Sbjct: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 56.2 bits (134), Expect = 4e-07
Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 404 PQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINEC--- 460
P+G+ A + + + C + G C+ + + +C C G+ G C ++ C
Sbjct: 2596 PEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPE 2655
Query: 461 HSDP--CQNDATCLDKIGGFTCLCMPGFKGVHCE 492
H P C ATC+ G+TC C G G++CE
Sbjct: 2656 HDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 56.2 bits (134), Expect = 4e-07
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 6/103 (5%)
Query: 755 EVDKNECLSNPCQNGGTCDNLVNG--YRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFD 812
+ D C N C+NGG C VNG + C C + G C ++ C +N CL+Q C
Sbjct: 2873 DCDGTACGYNTCRNGGEC--TVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIP 2929
Query: 813 DIS-GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNF 854
D S Y+C C L + G+ C+ + + N+ + PN+
Sbjct: 2930 DQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNY 2972
Score = 56.2 bits (134), Expect = 4e-07
Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 4/81 (4%)
Query: 141 ECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL- 199
+C T AC + C NG CT FSC+CL + G C V+ C + C H C+
Sbjct: 2873 DCDGT-ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-C-LNNLCLHQSLCIP 2929
Query: 200 NLPGSYQCQCPQGFTGQYCDS 220
+ SY C C G+ G+YC++
Sbjct: 2930 DQSFSYSCLCTLGWVGRYCEN 2950
Score = 55.5 bits (132), Expect = 7e-07
Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 395 LNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE 454
+N Q + G KG D D A N C + G+C F C CL +AG C
Sbjct: 2853 INNQELQLTEFGAKGGSNVGDCDGTA-CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN 2911
Query: 455 MDINECHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCE 492
++ C ++ C + + C+ D+ ++CLC G+ G +CE
Sbjct: 2912 QSVS-CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 53.9 bits (128), Expect = 2e-06
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 298 DVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI-DR 356
D D N C+NGG C + C C+ W+G+ C++++ C C S CI D+
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
Query: 357 VASFSCMCPEGKAGLLC 373
S+SC+C G G C
Sbjct: 2932 SFSYSCLCTLGWVGRYC 2948
Score = 53.5 bits (127), Expect = 2e-06
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 5/78 (6%)
Query: 264 CPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNG-GY 322
C +H C+N G C+ C CP ++G+ C C + N C NG TC ++G
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASC--ENNPCGNGATCVPKSGTDI 2394
Query: 323 GCVCVNGWSGDDCSENID 340
C+C G SG C++ I+
Sbjct: 2395 VCLCPYGRSGPLCTDAIN 2412
Score = 53.5 bits (127), Expect = 2e-06
Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 10/91 (10%)
Query: 760 ECLSNPCQ-----NGGTCDNLVNGYRCTCKKGFKGYNCQVNIDEC-----ASNPCLNQGT 809
+C ++PC NGGTC C C G+KG C + C + C T
Sbjct: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Query: 810 CFDDISGYTCHCVLPYTGKNCQTVLAPCSPN 840
C GYTC C L TG C+ L+ P+
Sbjct: 2668 CISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
Score = 53.1 bits (126), Expect = 3e-06
Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 10/90 (11%)
Query: 451 PRCEMDINECHSDPCQ-----NDATCLDKIGGFTCLCMPGFKGVHCELEINECQ-----S 500
P + +CH+ PC N TC++ C C G+KG C ++ C
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 501 NPCVNNGQCVDKVNRFQCLCPPGFTGPVCQ 530
+ C C+ + + C CP G TG C+
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 53.1 bits (126), Expect = 3e-06
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 799 CASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
C N C N G C + + ++C C+ + G C ++ C N C + ++C +F SY+
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSF-SYS 2936
Query: 859 CLCAPGWQGQRC 870
CLC GW G+ C
Sbjct: 2937 CLCTLGWVGRYC 2948
Score = 52.8 bits (125), Expect = 4e-06
Identities = 27/74 (36%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 427 CEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIG-GFTCLCMPG 485
C + G C++ + CEC + Y+G C+ C ++PC N ATC+ K G CLC G
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
Query: 486 FKGVHCELEINECQ 499
G C IN Q
Sbjct: 2402 RSGPLCTDAINITQ 2415
Score = 52.4 bits (124), Expect = 6e-06
Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 342 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNG-QYI 400
CA C TCI + C CP +G LC +C +NPC GA C P +G +
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF-ASCENNPCGNGATC--VPKSGTDIV 2395
Query: 401 CTCPQGYKGADCTEDVD 417
C CP G G CT+ ++
Sbjct: 2396 CLCPYGRSGPLCTDAIN 2412
Score = 52.0 bits (123), Expect = 7e-06
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Query: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCI-DHPNGYEC 556
C N C N G+C F C C P + G C + C + CL+ + CI D Y C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 557 QCATGFTGVLCE 568
C G+ G CE
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 50.4 bits (119), Expect = 2e-05
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 182 DVNECDIP--GH--CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCR 237
++ C +P H C++ GTC++ + C+CP+ ++G+ C + C +PC NG TC
Sbjct: 2330 NIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCV 2387
Query: 238 QTGDFTFECNCLPGFEGSTC 257
C C G G C
Sbjct: 2388 PKSGTDIVCLCPYGRSGPLC 2407
Score = 50.1 bits (118), Expect = 3e-05
Identities = 28/72 (38%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 686 CASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN-CTGGLS-GYKC 743
C N CR G C F C C +C V+ CL+N C+H + C S Y C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
Query: 744 LCDAGWVGINCE 755
LC GWVG CE
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 49.7 bits (117), Expect = 4e-05
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 6/83 (7%)
Query: 64 HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRP---CLNGGT 120
H PC +C NGGTC+ C C +G+ G C + S P C G T
Sbjct: 2610 HASPCSLMKCGNGGTCIESGT--SVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Query: 121 CHMLSRDTYECTCQVGFTGKECQ 143
C L Y C C +G TG C+
Sbjct: 2668 CISLPHG-YTCFCPLGTTGIYCE 2689
Score = 48.9 bits (115), Expect = 6e-05
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 11/84 (13%)
Query: 98 GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 157
G C Y+T C NGG C ++ T+ C C + G C + +CL++ C + S
Sbjct: 2876 GTACGYNT---------CRNGGEC-TVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQS 2925
Query: 158 TCTTVAN-QFSCKCLTGFTGQKCE 180
C + +SC C G+ G+ CE
Sbjct: 2926 LCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 48.5 bits (114), Expect = 8e-05
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 8/103 (7%)
Query: 641 NCEINFDDCASNPCIH-GICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCI- 698
NC + + CA + C + G C+ C C ++G+ C C +NPC GATC+
Sbjct: 2333 NCHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVP 2388
Query: 699 NGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGY 741
C+CP G P C +N ++ P G G + +
Sbjct: 2389 KSGTDIVCLCPYGRSGPLCTDAIN--ITQPRFSGTDAFGYTSF 2429
Score = 48.5 bits (114), Expect = 8e-05
Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
C N G C++ N +C+CP + G+ CQ CE N C NG TCV ++ C C
Sbjct: 2344 CRNNGTCIS-DNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCVPKSGT-DIVCLCPY 2400
Query: 95 GFTGEDC 101
G +G C
Sbjct: 2401 GRSGPLC 2407
Score = 47.8 bits (112), Expect = 1e-04
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 454 EMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCV-DK 512
+ D C + C+N C F+C C+P + G C ++ C +N C++ C+ D+
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQ 2931
Query: 513 VNRFQCLCPPGFTGPVCQ 530
+ CLC G+ G C+
Sbjct: 2932 SFSYSCLCTLGWVGRYCE 2949
Score = 47.4 bits (111), Expect = 2e-04
Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 13/90 (14%)
Query: 1265 INECLSNPCS----SEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVC-----PQMPCLN 1315
+ +C ++PCS G CI+ C C + + G C V C P C
Sbjct: 2606 VGQCHASPCSLMKCGNGGT-CIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSR 2664
Query: 1316 GGTCAVASNMPDGFICRCPPGFSGARCQSS 1345
G TC ++P G+ C CP G +G C+ +
Sbjct: 2665 GATCI---SLPHGYTCFCPLGTTGIYCEQA 2691
Score = 47.4 bits (111), Expect = 2e-04
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 5/76 (6%)
Query: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRD 127
C N C+NGG C +CRC + G C S S ++ CL+ C
Sbjct: 2879 CGYNTCRNGGECTVNGT--TFSCRCLPDWAGNTCNQSVS---CLNNLCLHQSLCIPDQSF 2933
Query: 128 TYECTCQVGFTGKECQ 143
+Y C C +G+ G+ C+
Sbjct: 2934 SYSCLCTLGWVGRYCE 2949
Score = 47.0 bits (110), Expect = 2e-04
Identities = 75/335 (22%), Positives = 111/335 (33%), Gaps = 85/335 (25%)
Query: 877 CISKPCMNHGLCHN---TQG--SYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVN 931
C C N G CH + G S+ C+CP F+G CE ++ G N
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE-----------KDAGLFFPSFN 2151
Query: 932 TFSCLCLPGFTGDKCQTDMNECLS-----EPCKNGGTCSDYVNSYTCKCQ-------AGF 979
S L LP F + + N ++ + GT Y N C Q G
Sbjct: 2152 GNSYLELP-FLKFVLEKEHNRTVTIYLTIKTNSLNGTIL-YSNGNNCGKQFLHLFLVEGR 2209
Query: 980 DGVH--CENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNE 1037
V C N+ N T S+ ++ T + PVG G C+ E+ P +
Sbjct: 2210 PSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKK 2269
Query: 1038 GTCVDGLG-TYRCSCPLGYT--------------------------------------GK 1058
T + Y S LG+ GK
Sbjct: 2270 DTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGK 2329
Query: 1059 NCQTL-VNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVE 1117
N + V C+ C+N GTC+ C CP ++G C SC+
Sbjct: 2330 NIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCE----------N 2377
Query: 1118 HLCQHSGVCI-NAGNTHYCQCPLGYTGSYCEEQLD 1151
+ C + C+ +G C CP G +G C + ++
Sbjct: 2378 NPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 47.0 bits (110), Expect = 2e-04
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVA-NQFSCKCLTG 173
C N GTC + + C C ++GK CQ+ +C ++PC NG+TC + C C G
Sbjct: 2344 CRNNGTC-ISDNENLFCECPRLYSGKLCQFA-SCENNPCGNGATCVPKSGTDIVCLCPYG 2401
Query: 174 FTGQKCETDVN 184
+G C +N
Sbjct: 2402 RSGPLCTDAIN 2412
Score = 46.6 bits (109), Expect = 3e-04
Identities = 30/85 (35%), Positives = 37/85 (43%), Gaps = 6/85 (7%)
Query: 1183 NCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCM 1242
NC V C + C+N GTCI + C CP G LC+ C P C NG C+
Sbjct: 2333 NCH--VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNP-CGNGATCV 2387
Query: 1243 DRIG-GYSCRCLPGFAGERCEGDIN 1266
+ G C C G +G C IN
Sbjct: 2388 PKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 46.6 bits (109), Expect = 3e-04
Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 8/80 (10%)
Query: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRD 127
C + C+N GTC++ C C ++G+ CQ+++ + PC NG TC S
Sbjct: 2339 CAHHLCRNNGTCISDNE--NLFCECPRLYSGKLCQFASCE----NNPCGNGATCVPKSGT 2392
Query: 128 TYECTCQVGFTGKECQWTDA 147
C C G +G C TDA
Sbjct: 2393 DIVCLCPYGRSGPLC--TDA 2410
Score = 46.2 bits (108), Expect = 4e-04
Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 13/96 (13%)
Query: 649 CASNPCI------HGICMDGINRYSCVCSPGFTGQRCNIDIDEC-----ASNPCRKGATC 697
C ++PC G C++ C C+ G+ G C + C + C +GATC
Sbjct: 2609 CHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATC 2668
Query: 698 INGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN 733
I+ +G+ C CP G C ++ +S+P N
Sbjct: 2669 ISLPHGYTCFCPLGTTGIYCEQALS--ISDPSFRSN 2702
Score = 46.2 bits (108), Expect = 4e-04
Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 570 NIDNCDPDPCHHGQCQDGID------SYTCICNPGYMGAICSDQIDECYSSPCLNDGRCI 623
N+ +CD C + C++G + +++C C P + G C+ + C ++ CL+ CI
Sbjct: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCI 2928
Query: 624 -DLVNGYQCNCQPGTSGVNCE 643
D Y C C G G CE
Sbjct: 2929 PDQSFSYSCLCTLGWVGRYCE 2949
Score = 45.8 bits (107), Expect = 5e-04
Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 611 CYSSPCLNDGRCIDLVNG--YQCNCQPGTSGVNCEINFDDCASNPCIH-GICM-DGINRY 666
C + C N G C VNG + C C P +G C + C +N C+H +C+ D Y
Sbjct: 2879 CGYNTCRNGGECT--VNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSY 2935
Query: 667 SCVCSPGFTGQRC 679
SC+C+ G+ G+ C
Sbjct: 2936 SCLCTLGWVGRYC 2948
Score = 45.4 bits (106), Expect = 7e-04
Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 7/94 (7%)
Query: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNP--CEHA 430
CH C C G C + + C C G+KG+ CTE V C + P C
Sbjct: 2609 CHASP-CSLMKCGNGGTCIESGTS--VYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 431 GKCVNTDGAFHCECLKGYAGPRCEMDINECHSDP 464
C++ + C C G G CE ++ SDP
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALS--ISDP 2697
Score = 45.4 bits (106), Expect = 7e-04
Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 171 LTGFTGQKCETDVNECDIPG----HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCA 226
LT F G K ++V +CD C++GG C ++ C+C + G C+ V C
Sbjct: 2860 LTEF-GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQS-VSCL 2917
Query: 227 PSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE 258
+ C++ C F++ C C G+ G CE
Sbjct: 2918 NNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 45.4 bits (106), Expect = 7e-04
Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Query: 536 CSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQC-QDGIDSYTCI 594
C C NG +C + + C+C + G C +++ + H C D SY+C+
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCL 2938
Query: 595 CNPGYMGAICSDQ 607
C G++G C ++
Sbjct: 2939 CTLGWVGRYCENK 2951
Score = 45.4 bits (106), Expect = 7e-04
Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Query: 342 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYIC 401
C + +C G C +FSC C AG C+ +C++N C +LC + + Y C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQ-SFSYSC 2937
Query: 402 TCPQGYKGADC 412
C G+ G C
Sbjct: 2938 LCTLGWVGRYC 2948
Score = 44.3 bits (103), Expect = 0.002
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 753 NCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFD 812
NC V C + C+N GTC + C C + + G CQ C +NPC N TC
Sbjct: 2333 NCHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVP 2388
Query: 813 DISGYTCHCVLPY 825
SG C+ PY
Sbjct: 2389 K-SGTDIVCLCPY 2400
Score = 44.3 bits (103), Expect = 0.002
Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327
C + C + G+ CI + C C ++G+ C+ C PC NG TC S
Sbjct: 2339 CAHHLCRNNGT--CISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSG--T 2392
Query: 1328 GFICRCPPGFSGARC 1342
+C CP G SG C
Sbjct: 2393 DIVCLCPYGRSGPLC 2407
Score = 44.3 bits (103), Expect = 0.002
Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINEC---LSNPCSSEGSLDCIQLTNDYLCV 1291
C NGG C++ C C G+ G C ++ C P CI L + Y C
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
Query: 1292 CRSAFTGRHCETFVDV 1307
C TG +CE + +
Sbjct: 2679 CPLGTTGIYCEQALSI 2694
Score = 43.9 bits (102), Expect = 0.002
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 6/94 (6%)
Query: 1282 IQLTNDYLCVCRSAFTGRHCET-FVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGA 1340
+Q+ N + A G++ E V C C N GTC ++ N + C CP +SG
Sbjct: 2312 LQVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTC-ISDN--ENLFCECPRLYSGK 2368
Query: 1341 RCQ-SSCGQVKCRKGEQCV-HTASGPRCFCPSPR 1372
CQ +SC C G CV + + C CP R
Sbjct: 2369 LCQFASCENNPCGNGATCVPKSGTDIVCLCPYGR 2402
Score = 43.9 bits (102), Expect = 0.002
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 24/106 (22%)
Query: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYC---------QHRDPC 68
C A+P ++C +G C+ G V YC C G+ G +C +H P
Sbjct: 2609 CHASPCSLMKCGNG-GTCIESGTSV-------YCNCTTGWKGSFCTETVSTCDPEHDPP- 2659
Query: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ--YSTSHPCFVS 112
+ C G TC+ ++ TC C G TG C+ S S P F S
Sbjct: 2660 --HHCSRGATCI--SLPHGYTCFCPLGTTGIYCEQALSISDPSFRS 2701
Score = 43.9 bits (102), Expect = 0.002
Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 2/76 (2%)
Query: 31 GYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATC 90
GY C N G C T + T C+C + G C C N C + C+ +C
Sbjct: 2880 GYNTCRNGGEC-TVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSF-SYSC 2937
Query: 91 RCASGFTGEDCQYSTS 106
C G+ G C+ TS
Sbjct: 2938 LCTLGWVGRYCENKTS 2953
Score = 42.4 bits (98), Expect = 0.006
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGS-YQ 206
C H C N TC + C+C ++G+ C+ C+ C +G TC+ G+
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCE-NNPCGNGATCVPKSGTDIV 2395
Query: 207 CQCPQGFTGQYC 218
C CP G +G C
Sbjct: 2396 CLCPYGRSGPLC 2407
Score = 42.4 bits (98), Expect = 0.006
Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 11/70 (15%)
Query: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ---SSCGQVK-----CRKGEQCVH 1359
C M C NGGTC + C C G+ G+ C S+C C +G C+
Sbjct: 2614 CSLMKCGNGGTCIESGT---SVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCIS 2670
Query: 1360 TASGPRCFCP 1369
G CFCP
Sbjct: 2671 LPHGYTCFCP 2680
Score = 40.0 bits (92), Expect = 0.028
Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 17/85 (20%)
Query: 569 ENIDNCDPDPCHH------GQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRC 622
+NI+NC C H G C ++ C C Y G +C Q C ++PC N C
Sbjct: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATC 2386
Query: 623 I-----DLVNGYQCNCQPGTSGVNC 642
+ D+V C C G SG C
Sbjct: 2387 VPKSGTDIV----CLCPYGRSGPLC 2407
Score = 39.3 bits (90), Expect = 0.049
Identities = 26/77 (33%), Positives = 31/77 (40%), Gaps = 4/77 (5%)
Query: 680 NIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLS 739
N + CA + CR TCI+ C CP C Q C +NPC +G S
Sbjct: 2333 NCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKS 2390
Query: 740 G--YKCLCDAGWVGINC 754
G CLC G G C
Sbjct: 2391 GTDIVCLCPYGRSGPLC 2407
Score = 38.9 bits (89), Expect = 0.063
Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 5/48 (10%)
Query: 115 CLNGGTCHMLSRDT----YECTCQVGFTGKECQWTDACLSHPCANGST 158
C NGGTCH + + ++C C + FTG+ C+ DA L P NG++
Sbjct: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE-KDAGLFFPSFNGNS 2154
Score = 37.7 bits (86), Expect = 0.14
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 5/40 (12%)
Query: 264 CPNHRCQNGGVC-----VDGVNTYNCRCPPQWTGQFCTED 298
C C NGG C G+ ++ C CP +TG+FC +D
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 37.4 bits (85), Expect = 0.18
Identities = 29/109 (26%), Positives = 35/109 (32%), Gaps = 34/109 (31%)
Query: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCF 1367
C C NGG C V F CRC P ++G C S
Sbjct: 2879 CGYNTCRNGGECTVNGTT---FSCRCLPDWAGNTCNQSV--------------------- 2914
Query: 1368 CPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTA 1416
C ++ C H C P Q YSC C + G CE T+
Sbjct: 2915 ---------SCLNNLCLHQSLCIPD-QSFSYSCLCTLGWVGRYCENKTS 2953
Score = 35.8 bits (81), Expect = 0.54
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 22/93 (23%)
Query: 1336 GFSGARCQSS-CGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPC-QHGGSCHPQR 1393
G S +C +S C +KC G C+ SG +C +C +G S C + +C P+
Sbjct: 2603 GRSVGQCHASPCSLMKCGNGGTCIE--SGTSVYC----NCTTGWKGSFCTETVSTCDPEH 2656
Query: 1394 QPPY--------------YSCQCAPPFSGSRCE 1412
PP+ Y+C C +G CE
Sbjct: 2657 DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 34.3 bits (77), Expect = 1.6
Identities = 18/43 (41%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 1307 VCPQMPCLNGGTC--AVASNMPDGFICRCPPGFSGARCQSSCG 1347
VC Q C NGGTC S+ F C CP F+G C+ G
Sbjct: 2102 VCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAG 2144
Score = 34.3 bits (77), Expect = 1.6
Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 1191 CQNQPCQNGGTCIDL-----VNHFKCSCPPGTRGLLCEEN 1225
CQ C NGGTC + + F+C CP G CE++
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 34.3 bits (77), Expect = 1.6
Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 13/46 (28%)
Query: 179 CETDVNECDIPGHCQHGGTCLNL-----PGSYQCQCPQGFTGQYCD 219
C+ DV C +GGTC + S+QC CP FTG++C+
Sbjct: 2103 CQQDV--------CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
Score = 33.9 bits (76), Expect = 2.0
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Query: 225 CAPSPCVNGGTCR----QTGDFTFECNCLPGFEGSTCERN 260
C C NGGTC +G +F+C+C F G CE++
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 33.5 bits (75), Expect = 2.7
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 5/70 (7%)
Query: 1346 CGQVKCRKGEQCVHTASGPRCFCP---SPRDCE-SGCASSPCQHGGSCHPQRQPPYYSCQ 1401
C CR C+ C CP S + C+ + C ++PC +G +C P+ C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIV-CL 2397
Query: 1402 CAPPFSGSRC 1411
C SG C
Sbjct: 2398 CPYGRSGPLC 2407
Score = 33.1 bits (74), Expect = 3.5
Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 7/59 (11%)
Query: 498 CQSNPCVNNGQC-----VDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP 551
CQ + C N G C + FQC CP FTG C+ D P NG ++ P
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAG--LFFPSFNGNSYLELP 2159
Score = 33.1 bits (74), Expect = 3.5
Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 11/59 (18%)
Query: 1373 DCE-SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYC 1430
DC+ + C + C++GG C +SC+C P ++G+ C +CL+ C
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTT--FSCRCLPDWAGNTC--------NQSVSCLNNLC 2921
Score = 32.0 bits (71), Expect = 7.8
Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 7/52 (13%)
Query: 1102 NVSCDIAASRRGVLVEHLCQHSGVC----INAGNTHY-CQCPLGYTGSYCEE 1148
+VS +AA V + +C + G C +++G + C CPL +TG +CE+
Sbjct: 2092 SVSPSVAAP--SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK 2141
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 526 bits (1354), Expect = e-148
Identities = 265/771 (34%), Positives = 387/771 (50%), Gaps = 86/771 (11%)
Query: 595 CNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP- 653
C G+MG C+ I SP G C + G C CQ G G+ C D C +P
Sbjct: 220 CMEGWMGPECNRAICRQGCSP--KHGSC--KLPG-DCRCQYGWQGLYC----DKCIPHPG 270
Query: 654 CIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASN-PCRKGATCIN-GVNGFRCICPEG 711
C+HGIC + + C+C + GQ C+ D++ C ++ PC G TC N G + ++C CPEG
Sbjct: 271 CVHGICNEP---WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEG 327
Query: 712 PHHPSCYSQVNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGG 770
P+C + CLS+PC + G+C G++C C GW G C + ++C N C +GG
Sbjct: 328 YSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387
Query: 771 TCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
TC +LVNG++C C + G CQ++ +EC + PC+N +C + I+ Y C C+ + G+NC
Sbjct: 388 TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447
Query: 831 QTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHN 890
+ C C+N A C++ N Y C+C PG+ G C DIDEC S PC+N G C N
Sbjct: 448 DININDCL-GQCQNDASCRDLVN--GYRCICPPGYAGDHCERDIDECASNPCLNGGHCQN 504
Query: 891 TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM 950
+ C CP GFSG C+ DID C NPCQNG C + + + C C + G C
Sbjct: 505 EINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLK 564
Query: 951 NECLSEPCKNGGTCS------------DYVNS----------------YTCKCQAGFDGV 982
+ C + PC+ +C+ Y++S +TC C GF G
Sbjct: 565 DHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGT 624
Query: 983 HCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVD 1042
+C NIN+C + C NGGTC+DG+NS+ C+C G+ G++C IN+CS +PC N GTC D
Sbjct: 625 YCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRD 684
Query: 1043 GLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPN 1102
+ + C C G+ GK C + + C + C N GTC + +C+CP GW G C++
Sbjct: 685 LVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNI-- 742
Query: 1103 VSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGA 1162
+R + + C + G C+ G + C C G+ G C + ++C+ +PC +
Sbjct: 743 -------ARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSG 795
Query: 1163 TCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLC 1222
TC D YRCEC PG+ G +C ++ECQ+ PC G TC+D +N ++C CPPG G C
Sbjct: 796 TCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKC 855
Query: 1223 EENIDDCARGPHCLNGGQCMDRIGGY-----SCRCLPGFAGERCEGDINECLSNPC-SSE 1276
+E G C+ G + + +C+CL G R C PC +
Sbjct: 856 QE-----VSGRPCITMGSVIPDGAKWDDDCNTCQCLNG----RIACSKVWCGPRPCLLHK 906
Query: 1277 GSLDCIQLTNDYLCVCRSAFTGRHCETFV-DVCPQMPCLNGGTCAVASNMP 1326
G +C +G+ C + D C PC G C +S P
Sbjct: 907 GHSECP--------------SGQSCIPILDDQCFVHPCTGVGECRSSSLQP 943
Score = 515 bits (1326), Expect = e-145
Identities = 267/768 (34%), Positives = 373/768 (48%), Gaps = 86/768 (11%)
Query: 320 GGYGC------VCVNGWSGDDCSENIDDCAFASCTP--GSTCIDRVASFSCMCPEGKAGL 371
G Y C C+ GW G +C+ I C+P GS + C C G GL
Sbjct: 208 GHYACDQNGNKTCMEGWMGPECNRAI---CRQGCSPKHGSCKLPG----DCRCQYGWQGL 260
Query: 372 LCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAG 431
C D CI +P +C N + C C + G C +D++ C PC + G
Sbjct: 261 YC---DKCIPHPGCVHGIC-----NEPWQCLCETNWGGQLCDKDLNYCG--THQPCLNGG 310
Query: 432 KCVNTD-GAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVH 490
C NT + C C +GY+GP CE+ + C SDPC N +C + GF C C PG+ G
Sbjct: 311 TCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPT 370
Query: 491 CELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDH 550
C I++C N C + G C D VN F+C+CPP +TG CQ+D ++C + PC+N C +
Sbjct: 371 CSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNL 430
Query: 551 PNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDE 610
Y C C G+ G C+ NI++C + C+D ++ Y CIC PGY G C IDE
Sbjct: 431 IASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDE 490
Query: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYSCV 669
C S+PCLN G C + +N +QC C G SG C+++ D C NPC +G C + + Y C
Sbjct: 491 CASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCK 550
Query: 670 CSPGFTGQRCNIDIDECASNPCRKGATC-------------------INGVNG------- 703
C + G+ C+ D C + PC +C + G +G
Sbjct: 551 CPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSG 610
Query: 704 --FRCICPEGPHHPSCYSQVNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNE 760
F C C +G C+ +N+C SNPC + G C G++ YKC+C GW G CE + N+
Sbjct: 611 GKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND 670
Query: 761 CLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCH 820
C NPC NGGTC +LVN + C CK G+KG C +C C N GTC+D+ + C
Sbjct: 671 CSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCM 730
Query: 821 CVLPYTGKNCQTVL-APCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS 879
C + G C + C PNPC N C N ES+TC+C GW+G C + ++C
Sbjct: 731 CPGGWEGTTCNIARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSP 788
Query: 880 KPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLP 939
PC N G C + Y CEC PGF+G DC +I++C ++PC G +C+D +N + C+C P
Sbjct: 789 HPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPP 848
Query: 940 GFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNG 999
G +G KCQ E PC G+ DG +++ N C C NG
Sbjct: 849 GHSGAKCQ----EVSGRPCITMGSVIP-------------DGAKWDDDCNTC---QCLNG 888
Query: 1000 GTCVDGI--NSFSCLCPVGF----TGSFCLHEI-NECSSHPCLNEGTC 1040
+ CL G +G C+ + ++C HPC G C
Sbjct: 889 RIACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGEC 936
Score = 504 bits (1298), Expect = e-142
Identities = 279/816 (34%), Positives = 383/816 (46%), Gaps = 150/816 (18%)
Query: 41 CVTYHNGTG---YCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFT 97
C Y+ G G +C+ + F G Y C++N G TC G+
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYA-----CDQN--------------GNKTCM--EGWM 225
Query: 98 GEDCQYSTSHPCFVSRPCLNG-----GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 152
G +C + C G G+C + +C CQ G+ G C D C+ HP
Sbjct: 226 GPECNRAI---------CRQGCSPKHGSCKLPG----DCRCQYGWQGLYC---DKCIPHP 269
Query: 153 -CANGSTCTTVANQ-FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL-PGSYQCQC 209
C +G + N+ + C C T + GQ C+ D+N C C +GGTC N P YQC C
Sbjct: 270 GCVHG-----ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC 324
Query: 210 PQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRC 269
P+G++G C+ C PC N G+C++T FEC C PG+ G TC NIDDC + C
Sbjct: 325 PEGYSGPNCEIAEHACLSDPCHNRGSCKETS-LGFECECSPGWTGPTCSTNIDDCSPNNC 383
Query: 270 QNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP----------------------- 306
+GG C D VN + C CPPQWTG+ C D +EC +P
Sbjct: 384 SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWM 443
Query: 307 ------------NACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI 354
CQN +C + GY C+C G++GD C +ID+CA C G C
Sbjct: 444 GQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQ 503
Query: 355 DRVASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCT 413
+ + F C+CP G +G LC LD D C NPC GA C Y C CP+ Y+G +C+
Sbjct: 504 NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRA--SDYFCKCPEDYEGKNCS 561
Query: 414 -----------EDVDECAMA-------------NSNPCEHAGKCVN-TDGAFHCECLKGY 448
E +D C +A +SN C GKC + + G F C+C KG+
Sbjct: 562 HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF 621
Query: 449 AGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQ 508
G C +IN+C S+PC+N TC+D + + C+C G++G +CE IN+C NPC N G
Sbjct: 622 TGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGT 681
Query: 509 CVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE 568
C D VN F C C G+ G C C C NG C D + ++C C G+ G C
Sbjct: 682 CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCN 741
Query: 569 -ENIDNCDPDPCHH-GQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLV 626
+C P+PCH+ G C +S+TC+C G+ G IC+ ++C PC N G C+D
Sbjct: 742 IARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGD 801
Query: 627 NGYQCNCQPGTSGVNCEINFDDCASNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDIDE 685
N Y+C C PG +G +C IN ++C S+PC G C+D IN Y CVC PG +G +C E
Sbjct: 802 NWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKC----QE 857
Query: 686 CASNPC-RKGATCINGV----NGFRCICPEGPHHPSCYSQVNECLSNPCI----HGNCTG 736
+ PC G+ +G + C C G +C S+V C PC+ H C
Sbjct: 858 VSGRPCITMGSVIPDGAKWDDDCNTCQCLNG--RIAC-SKV-WCGPRPCLLHKGHSECPS 913
Query: 737 GLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTC 772
G S L D +C +PC G C
Sbjct: 914 GQSCIPILDD-------------QCFVHPCTGVGEC 936
Score = 475 bits (1223), Expect = e-133
Identities = 253/770 (32%), Positives = 355/770 (46%), Gaps = 104/770 (13%)
Query: 708 CPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQ 767
C EG P C + +P HG+C L G C C GW G+ C+ +C+ +P
Sbjct: 220 CMEGWMGPECNRAICRQGCSPK-HGSCK--LPG-DCRCQYGWQGLYCD----KCIPHPGC 271
Query: 768 NGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASN-PCLNQGTCFDD-ISGYTCHCVLPY 825
G C+ ++C C+ + G C +++ C ++ PCLN GTC + Y C C Y
Sbjct: 272 VHGICNE---PWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY 328
Query: 826 TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNH 885
+G NC+ C +PC N CKE+ + C C+PGW G C+ +ID+C C +
Sbjct: 329 SGPNCEIAEHACLSDPCHNRGSCKETSL--GFECECSPGWTGPTCSTNIDDCSPNNCSHG 386
Query: 886 GLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDK 945
G C + + C CPP ++G C+ D ++C A PC N SC + + ++ C CLPG+ G
Sbjct: 387 GTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQN 446
Query: 946 CQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
C ++N+CL + C+N +C D VN Y C C G+ G HCE +I+EC + C NGG C +
Sbjct: 447 CDININDCLGQ-CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNE 505
Query: 1006 INSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVN 1065
IN F CLCP GF+G+ C +I+ C +PC N C + Y C CP Y GKNC L +
Sbjct: 506 INRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKD 565
Query: 1066 LCSRSPCKNKGTCV----------------------QKKAESQ------CLCPSGWAGAY 1097
C +PC+ +C K +SQ C C G+ G Y
Sbjct: 566 HCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTY 625
Query: 1098 CDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNP 1157
C C+ + C++ G CI+ N++ C C G+ G+YCE +++C+ NP
Sbjct: 626 CHENINDCE----------SNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP 675
Query: 1158 CQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGT 1217
C +G TC D + + C+C G++G C +C C NGGTC D + FKC CP G
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW 735
Query: 1218 RGLLCE-ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSE 1276
G C C P C NGG C+ ++C C G+ G C + N+C +PC +
Sbjct: 736 EGTTCNIARNSSCLPNP-CHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNS 794
Query: 1277 GSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPG 1336
G+ C+ N Y C C F G C ++ C PC G TC N G+ C CPPG
Sbjct: 795 GT--CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEIN---GYRCVCPPG 849
Query: 1337 FSGARCQ---------------------SSCGQVKCRKGE-QCVHTASGPR-CF------ 1367
SGA+CQ C +C G C GPR C
Sbjct: 850 HSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHS 909
Query: 1368 -CPSPRDC----ESGCASSPCQHGGSCHPQRQPP---------YYSCQCA 1403
CPS + C + C PC G C P YY CA
Sbjct: 910 ECPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCA 959
Score = 417 bits (1072), Expect = e-116
Identities = 245/800 (30%), Positives = 353/800 (44%), Gaps = 120/800 (15%)
Query: 771 TCDNLVNGYRCT--CKKG---FKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPY 825
TCD+ G+ C C+ F Y C N ++ TC + G C+ +
Sbjct: 186 TCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNK----------TCMEGWMGPECNRAICR 235
Query: 826 TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNH 885
G CSP CK + C C GWQG C D+CI P H
Sbjct: 236 QG---------CSPKH----GSCKLPGD-----CRCQYGWQGLYC----DKCIPHPGCVH 273
Query: 886 GLCHNTQGSYMCECPPGFSGMDCEEDIDDCLAN-PCQNGGSCMD-GVNTFSCLCLPGFTG 943
G+C+ + C C + G C++D++ C + PC NGG+C + G + + C C G++G
Sbjct: 274 GICNEP---WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG 330
Query: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCV 1003
C+ + CLS+PC N G+C + + C+C G+ G C NI++C+ ++C +GGTC
Sbjct: 331 PNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQ 390
Query: 1004 DGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL 1063
D +N F C+CP +TG C + NEC + PC+N +C + + +Y C C G+ G+NC
Sbjct: 391 DLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDIN 450
Query: 1064 VNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHS 1123
+N C C+N +C +C+CP G+AG +C+ C + C +
Sbjct: 451 INDCL-GQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDEC----------ASNPCLNG 499
Query: 1124 GVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVN 1183
G C N N C CP G++G+ C+ +D C NPCQ+GA C + Y C+C Y+G N
Sbjct: 500 GHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKN 559
Query: 1184 CEYEVDECQNQPCQNGGTCIDLV----------------------------NHFKCSCPP 1215
C + D C+ PC+ +C + F C C
Sbjct: 560 CSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNK 619
Query: 1216 GTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
G G C ENI+DC P C NGG C+D + Y C C G+ G CE +IN+C NPC +
Sbjct: 620 GFTGTYCHENINDCESNP-CRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHN 678
Query: 1276 EGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPP 1335
G+ C L ND+ C C++ + G+ C + C + C NGGTC + D F C CP
Sbjct: 679 GGT--CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCY---DEGDAFKCMCPG 733
Query: 1336 GFSGARCQ----SSCGQVKCRKGEQCVHTASGPRCFC------PSPRDCESGCASSPCQH 1385
G+ G C SSC C G CV C C P + C+ PC +
Sbjct: 734 GWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYN 793
Query: 1386 GGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNS 1445
G+C +Y C+CAP F+G C + C S CA A C + N
Sbjct: 794 SGTCVDGDN--WYRCECAPGFAGPDCRINI-------NECQSSPCAFGA---TCVDEING 841
Query: 1446 HAC----QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSK 1501
+ C G C P S +P + D+ CNT +CL C SK
Sbjct: 842 YRCVCPPGHSGAKCQEVSGRPCITMGSVIP----DGAKWDDDCNTCQCLNGRIAC---SK 894
Query: 1502 TCKYDKYCADHFKDNHCDQG 1521
+ C H + C G
Sbjct: 895 VWCGPRPCLLHKGHSECPSG 914
Score = 417 bits (1071), Expect = e-116
Identities = 221/647 (34%), Positives = 315/647 (48%), Gaps = 69/647 (10%)
Query: 32 YEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRD-PCEKNRCQNGGTCVAQAMLGKATC 90
++PC+N G C C CPEG+ G C+ + C + C N G+C + LG C
Sbjct: 303 HQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSC-KETSLG-FEC 360
Query: 91 RCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW-TDACL 149
C+ G+TG C ST+ C +GGTC L + ++C C +TGK CQ + C
Sbjct: 361 ECSPGWTGPTC--STNIDDCSPNNCSHGGTCQDLV-NGFKCVCPPQWTGKTCQLDANECE 417
Query: 150 SHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC 209
+ PC N +C + + C CL G+ GQ C+ ++N+C G CQ+ +C +L Y+C C
Sbjct: 418 AKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC--LGQCQNDASCRDLVNGYRCIC 475
Query: 210 PQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRC 269
P G+ G +C+ CA +PC+NGG C Q F+C C GF G+ C+ +ID C + C
Sbjct: 476 PPGYAGDHCERDIDECASNPCLNGGHC-QNEINRFQCLCPTGFSGNLCQLDIDYCEPNPC 534
Query: 270 QNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP----------------------- 306
QNG C + + Y C+CP + G+ C+ D C P
Sbjct: 535 QNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYI 594
Query: 307 --NACQNGGTCANRNGG-YGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCM 363
N C G C +++GG + C C G++G C ENI+DC C G TCID V S+ C+
Sbjct: 595 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCI 654
Query: 364 CPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA 422
C +G G C + + C NPCH G C L + C C G+KG C +C A
Sbjct: 655 CSDGWEGAYCETNINDCSQNPCHNGGTC--RDLVNDFYCDCKNGWKGKTCHSRDSQCDEA 712
Query: 423 NSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDIN-ECHSDPCQNDATCLDKIGGFTCL 481
C + G C + AF C C G+ G C + N C +PC N TC+ FTC+
Sbjct: 713 T---CNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCV 769
Query: 482 CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC 541
C G++G C N+C +PC N+G CVD N ++C C PGF GP C+I+I++C S+PC
Sbjct: 770 CKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPC 829
Query: 542 LNGAKCIDHPNGYECQCATGFTGVLCEE-------NIDNCDP------DPCHHGQCQDG- 587
GA C+D NGY C C G +G C+E + + P D C+ QC +G
Sbjct: 830 AFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGR 889
Query: 588 -------IDSYTCICNPGY----MGAICSDQI-DECYSSPCLNDGRC 622
C+ + G+ G C + D+C+ PC G C
Sbjct: 890 IACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGEC 936
Score = 240 bits (613), Expect = 1e-62
Identities = 144/420 (34%), Positives = 194/420 (46%), Gaps = 69/420 (16%)
Query: 34 PCVNEGMCVTYHNGTGY-CKCPEGFLGEYCQH------RDPCE----------------- 69
PC N C Y+ + Y CKCPE + G+ C H PCE
Sbjct: 533 PCQNGAQC--YNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEG 590
Query: 70 -----KNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHML 124
N C G C +Q+ GK TC C GFTG C + + C S PC NGGTC +
Sbjct: 591 VRYISSNVCGPHGKCKSQSG-GKFTCDCNKGFTGTYC-HENINDC-ESNPCRNGGTC-ID 646
Query: 125 SRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDV 183
++Y+C C G+ G C+ + C +PC NG TC + N F C C G+ G+ C +
Sbjct: 647 GVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRD 706
Query: 184 NECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDF 242
++CD C +GGTC + +++C CP G+ G C+ + C P+PC NGGTC G+
Sbjct: 707 SQCD-EATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE- 764
Query: 243 TFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDEC 302
+F C C G+EG C +N +DC H C N G CVDG N Y C C P + G C +++EC
Sbjct: 765 SFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININEC 824
Query: 303 LLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENI------------------DDCAF 344
Q + C G TC + GY CVC G SG C E DDC
Sbjct: 825 --QSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNT 882
Query: 345 ASCTPGSTCIDRV--ASFSCM-------CPEGKAGLLCHLDDACISNPCHKGALCDTNPL 395
C G +V C+ CP G++ + LDD C +PC C ++ L
Sbjct: 883 CQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCIPI-LDDQCFVHPCTGVGECRSSSL 941
Score = 76.6 bits (187), Expect = 3e-13
Identities = 72/265 (27%), Positives = 97/265 (36%), Gaps = 73/265 (27%)
Query: 34 PCVNEGMCVTYHNGTGY-CKCPEGFLGEYC-QHRDPCEKNRCQNGGTCVAQAMLGKATCR 91
PC N G CV NG + C C EG+ G C Q+ + C + C N GTCV + C
Sbjct: 752 PCHNGGTCVV--NGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYR--CE 807
Query: 92 CASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ-------- 143
CA GF G DC+ + + S PC G TC + + Y C C G +G +CQ
Sbjct: 808 CAPGFAGPDCRININE--CQSSPCAFGATC-VDEINGYRCVCPPGHSGAKCQEVSGRPCI 864
Query: 144 -----------WTDACLSHPCANGS-TCTTV-ANQFSCKCLTGFT----GQKC------E 180
W D C + C NG C+ V C G + GQ C +
Sbjct: 865 TMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQ 924
Query: 181 TDVNECDIPGHCQHGG----------------TCLNLPGSY--QCQCPQGFTGQYCD--- 219
V+ C G C+ C N+ ++ + P T C
Sbjct: 925 CFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELR 984
Query: 220 ------------SLYVPCAPSPCVN 232
S+Y+ C PSP N
Sbjct: 985 NLNILKNVSAEYSIYIACEPSPSAN 1009
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 520 bits (1338), Expect = e-147
Identities = 453/1605 (28%), Positives = 657/1605 (40%), Gaps = 330/1605 (20%)
Query: 39 GMCVTYHN--GTGYCKCPEGFLGE----YCQHRDPCEKNR--CQNGGTCVAQAMLGKATC 90
G+C HN G+ C+CP G C + CE + C NG CV ++GK C
Sbjct: 1127 GVC---HNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNG-RCVN--LIGKYQC 1180
Query: 91 RCASGFTGEDCQYSTSHPCF---VSRPCLNGGTCHML---SRDTYECTCQVGFT----GK 140
C G+ +ST F + + G C S +YEC+CQ GF +
Sbjct: 1181 ACNPGY------HSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQR 1234
Query: 141 ECQWTDACLSHP-CANGSTCTTVANQFSCKCLTGFTGQ---KCETDVNECDIPGHCQHGG 196
C D C +P +G CT + ++ C C GF K DVNECD+ + G
Sbjct: 1235 SCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG 1294
Query: 197 TCLNLPGSYQCQCPQGFTGQY-----CDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPG 251
TC N GS+ C C G++G+ D C C T +F+C+C PG
Sbjct: 1295 TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAG-SFKCSCSPG 1353
Query: 252 FEGSTCE-RNIDDCPN--HRCQNGGVCVDGVNTYNCRCPPQWTGQ-FCTEDVDECLLQPN 307
+ G + ++D+C N H C C + + +Y C C +TG F D+DEC N
Sbjct: 1354 WIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLN 1413
Query: 308 ACQNGGTCANRNGGYGCVCVNGW----SGDDCSENIDDCA------FASC--TPG----- 350
C NG C N GGY C C G+ G C E+ID+C+ F +C PG
Sbjct: 1414 LCGNG-QCLNAPGGYRCECDMGFVPSADGKAC-EDIDECSLPNICVFGTCHNLPGLFRCE 1471
Query: 351 ----------------------------STCIDRVASFSCMCPEG------KAGLL---- 372
C++ S+ C CP + G +
Sbjct: 1472 CEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRS 1531
Query: 373 --CHLD-----------------------DACISNPCHKGALCDTNPL--NGQYICTCP- 404
C+LD C S G C+ P +Y CP
Sbjct: 1532 GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPG 1591
Query: 405 -QGYKGADCT---EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY---AGPRCEMDI 457
+G++ T ED+DEC C+ GKC+NT G+F C C GY R D+
Sbjct: 1592 GEGFRPNPITVILEDIDECQEL-PGLCQ-GGKCINTFGSFQCRCPTGYYLNEDTRVCDDV 1649
Query: 458 NECHSDPCQNDATCLDKIGGFTCLCMPGFKGVH-----CELEINECQSNPCVNNGQCVDK 512
NEC + TC + +G +TC+C P + V+ ++ + C N +N C +
Sbjct: 1650 NECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGE 1709
Query: 513 V--NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKC-IDHPNGYECQCATGFTGVLCE- 568
+ N + +C C +I + PC +C I + + C + G + +
Sbjct: 1710 LLFNMTKKMC-------CCSYNIGRAWNKPC---EQCPIPSTDEFATLCGSQRPGFVIDI 1759
Query: 569 -----ENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYMG----AICSDQIDECYSSP-C 616
+ID C P C +G C + + S+ C C G+ +C D IDEC + P C
Sbjct: 1760 YTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCED-IDECQNGPVC 1818
Query: 617 LNDGRCIDLVNGYQCNCQPG---TSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCS 671
+ CI+ Y+C+C+PG TS C + ++C P C HG C+D + + C+C
Sbjct: 1819 QRNAECINTAGSYRCDCKPGYRFTSTGQCN-DRNECQEIPNICSHGQCIDTVGSFYCLCH 1877
Query: 672 PGFT---GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG---PHHPSCYSQVNECL 725
GF Q +DI+EC + C G TC N + F C C G H+ C V+EC
Sbjct: 1878 TGFKTNDDQTMCLDINECERDACGNG-TCRNTIGSFNCRCNHGFILSHNNDCID-VDECA 1935
Query: 726 S---NPCIHGNCTGGLSGYKCLCDAGWV----GINCEVDKNECLSNPCQNG-GTCDNLVN 777
S N C +G C + ++C C+ G+ G C VD NECL P + GTC NL
Sbjct: 1936 SGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNLDG 1994
Query: 778 GYRCTCKKGFKGYN--CQVNIDECASNPCLNQ-GTCFDDISGYTCHCV----LPYTGKNC 830
YRC C G+ N C+ +IDEC P + GTC + + C C L +G+ C
Sbjct: 1995 SYRCICPPGYSLQNEKCE-DIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRC 2053
Query: 831 QTV-LAPCSPNPCENAAVCKESPNFESYTCLCA---PGWQGQRC---------------- 870
Q + ++ C +S N C CA GW G C
Sbjct: 2054 QDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGW-GDPCELCPTEPDEAFRQICP 2112
Query: 871 ------------TIDIDECISKPCMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDC- 915
+D+DEC HG C NT GSY CECP G+ +G +C D D+C
Sbjct: 2113 YGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC-VDTDECS 2171
Query: 916 LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT--DMNECLSEPCKNGGTCSDYVNSYTC 973
+ NPC N G+C + + F C C GF T D+NEC P C + SY C
Sbjct: 2172 VGNPCGN-GTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYEC 2230
Query: 974 KCQAGF----------DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TG 1019
KC G+ D CE ++CTE C + I ++ C+C G+ G
Sbjct: 2231 KCPVGYVLREDRRMCKDEDECEEGKHDCTEKQM----ECKNLIGTYMCICGPGYQRRPDG 2286
Query: 1020 SFCLHEINECSSHPCLNE-GTCVDGLGTYRCSCPLGYTGK----NC----------QTLV 1064
C+ E NEC + P + E G C++ G+Y C C G+T C + L
Sbjct: 2287 EGCVDE-NECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQ 2345
Query: 1065 NLCS-RSPCKNKGTCVQKKAESQCLCPS--GWAGAYCDVPNVSCDIAASR-----RGVL- 1115
N+C S +N T +S+C C GW G +C++ +A + RG +
Sbjct: 2346 NMCQIGSSNRNPVT------KSECCCDGGRGW-GPHCEICPFQGTVAFKKLCPHGRGFMT 2398
Query: 1116 ---------VEHLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECASNPCQHGA 1162
V H +G C+N +++C C GY TG+ C + L+EC P
Sbjct: 2399 NGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVD-LNECNQAPKPCNF 2457
Query: 1163 TCSDFIGGYRCECVPGY----QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG-- 1216
C + G Y+C C GY G +C+ ++DEC + C++ + F C CPPG
Sbjct: 2458 ICKNTEGSYQCSCPKGYILQEDGRSCK-DLDECATKQHNCQFLCVNTIGGFTCKCPPGFT 2516
Query: 1217 TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA----GERCEGDINECLSNP 1272
C +N + + C + G C + G ++C C GF+ G CE D++EC N
Sbjct: 2517 QHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDECEGNH 2575
Query: 1273 CSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVAS--NMPDGFI 1330
G C + Y C C + + + + CL+ C AS N +
Sbjct: 2576 RCQHG---CQNIIGGYRCSCPQGYLQHY--QWNQCVDENECLSAHICGGASCHNTLGSYK 2630
Query: 1331 CRCPPGF------SGARCQSSCGQVKCRKGEQCVHTASGPRCFCP 1369
C CP GF G + + CG + C +T G C CP
Sbjct: 2631 CMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCP 2675
Score = 486 bits (1252), Expect = e-137
Identities = 509/1832 (27%), Positives = 709/1832 (38%), Gaps = 432/1832 (23%)
Query: 35 CVNEGMCVTYHNGTGYCKCPEGF---LGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCR 91
C N G C+ G+ C+C +GF L C D CEKN C GG C+ G TC+
Sbjct: 460 CQN-GRCIPTP-GSCRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINNQ--GSYTCQ 514
Query: 92 CASGF----TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGF----TGKECQ 143
C +G+ T +C+ C + N G C + + ++ C C GF GK C+
Sbjct: 515 CRAGYQSTLTRTECR--DIDECLQNGRICNNGRC-INTDGSFHCVCNAGFHVTRDGKNCE 571
Query: 144 WTDAC-LSHPCANGSTCTTVANQFSCKCLTGF----TGQKCETDVNECDIPGHCQHGGTC 198
D C + + C NG C F C C GF G+ C+ D+NEC+ PG C + G C
Sbjct: 572 DMDECSIRNMCLNG-MCINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMN-GRC 628
Query: 199 LNLPGSYQCQC----PQGFTGQYCDSLYVPCAPSPCVNG---GTCRQT--GDFTFECNCL 249
+N GSY+C+C G G+ C ++ S C G G C + G T C
Sbjct: 629 VNTDGSYRCECFPGLAVGLDGRVCVDTHM---RSTCYGGYKRGQCIKPLFGAVTKSECCC 685
Query: 250 PGFE---GSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP 306
E G C+ CP QN Y C D++EC L P
Sbjct: 686 ASTEYAFGEPCQ----PCP---AQNSA-------EYQALCSSGPGMTSAGSDINECALDP 731
Query: 307 NACQNGGTCANRNGGYGCVCVNGWSGDDCSEN---IDDCAFAS--CTPGSTCIDRVASFS 361
+ C N G C N G Y C+C +G+ D +N I++C S C G C + SF
Sbjct: 732 DICPN-GICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ-CRNTPGSFV 789
Query: 362 CMCPEG---KAGL-LCHLDDACISNPCHKGALCDTNPLNGQYICTCP------------- 404
C CP+G K L C D C S+PC G +C +P G +IC C
Sbjct: 790 CTCPKGFIYKPDLKTCEDIDECESSPCING-VCKNSP--GSFICECSSESTLDPTKTICI 846
Query: 405 QGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFH------CE----CLKGYA---GP 451
+ KG +D N N +C ++ GA C+ C KGY+ G
Sbjct: 847 ETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGT 906
Query: 452 RCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPG---------------------FKG 488
+CE DI+EC P C+N C++ G F C C G ++
Sbjct: 907 QCE-DIDECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYED 964
Query: 489 VHCELEI-------------------NECQSNPCVNNGQCVDKVNRFQCLCP--PGF--- 524
C L I EC+ P N + ++ LCP PGF
Sbjct: 965 EECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPE-------YEELCPRGPGFATK 1017
Query: 525 ---TGPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGFTGVLCEEN---IDNC-- 574
G DI++C P C +G KC + ++C+C +GF E N ID C
Sbjct: 1018 EITNGKPFFKDINECKMIPSLCTHG-KCRNTIGSFKCRCDSGFALDSEERNCTDIDECRI 1076
Query: 575 DPDPCHHGQCQDGIDSYTCICNPGY-----MGAICSDQIDECYSSPCL-NDGRCIDLVNG 628
PD C GQC + + C C+ GY M C D IDEC P L G C +
Sbjct: 1077 SPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMD-IDECQRDPLLCRGGVCHNTEGS 1135
Query: 629 YQCNCQPG---TSGVNCEINFDDC--ASNPCIHGICMDGINRYSCVCSPGF--TGQRC-N 680
Y+C C PG + ++ I+ ++C +++ C +G C++ I +Y C C+PG+ T R
Sbjct: 1136 YRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFC 1195
Query: 681 IDIDECASNPCRKGATCINGVNGFRCICPEG----PHHPSCYSQVNECLSNP--CIHGNC 734
+DIDEC+ C N + C C G P SC + ++EC NP C G C
Sbjct: 1196 VDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSC-TDIDECEDNPNICDGGQC 1254
Query: 735 TGGLSGYKCLCDAGWVG---INCEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGF-- 787
T Y+CLC G++ + VD NEC NP C + GTC+N + C C G+
Sbjct: 1255 TNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLS-GTCENTKGSFICHCDMGYSG 1313
Query: 788 -KGYNCQVNIDEC--ASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQ-TVLAPCS--PNP 841
KG +I+EC ++ C C + + C C + G + T L CS +
Sbjct: 1314 KKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHM 1373
Query: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCT-IDIDECISK-PCMNHGLCHNTQGSYMCEC 899
C A CK + SY CLC G+ G T D+DEC +G C N G Y CEC
Sbjct: 1374 CSQHADCKNT--MGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCEC 1431
Query: 900 PPGF----SGMDCEEDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGF----TGDKCQTDM 950
GF G C EDID+C L N C G+C + F C C G+ +G C TD+
Sbjct: 1432 DMGFVPSADGKAC-EDIDECSLPNICV-FGTCHNLPGLFRCECEIGYELDRSGGNC-TDV 1488
Query: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCF--------NGGTC 1002
NECL G C + SY C C F+ + +C+ NG T
Sbjct: 1489 NECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTA 1548
Query: 1003 VD-----GINSFSCLCPVGFT-GSFC-----------------------------LHEIN 1027
G++ SC C +G G+ C L +I+
Sbjct: 1549 CSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDID 1608
Query: 1028 ECSSHPCLNE-GTCVDGLGTYRCSCPLGY----TGKNCQTLVNLCSRSPCKNKGTCVQKK 1082
EC P L + G C++ G+++C CP GY + C VN C GTC
Sbjct: 1609 ECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDD-VNECETPGICGPGTCYNTV 1667
Query: 1083 AESQCLCPSGW----AGAYC------------DVPNVSCDIAASRRGVLVEHLCQHSGVC 1126
C+CP + G C N +CD G L+ ++ + C
Sbjct: 1668 GNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD------GELLFNMTKKMCCC 1721
Query: 1127 I----NAGNTHYCQCPLGYTGSY---CEEQ---------------LDECASNP--CQHGA 1162
A N QCP+ T + C Q +DEC P C++G
Sbjct: 1722 SYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENG- 1780
Query: 1163 TCSDFIGGYRCECVPGY----QGVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPPGT 1217
C + +G +RCEC G+ + + CE ++DECQN P CQ CI+ ++C C PG
Sbjct: 1781 VCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKPGY 1839
Query: 1218 RGL---LCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG---DINECLSN 1271
R C + ++C P+ + GQC+D +G + C C GF + DINEC +
Sbjct: 1840 RFTSTGQCNDR-NECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERD 1898
Query: 1272 PCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDV----------CPQMPCLN------ 1315
C G+ C + C C F H +DV C C+N
Sbjct: 1899 AC---GNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQ 1955
Query: 1316 ------------GGTC---------------AVASNMPDGFICRCPPGFS--GARCQSSC 1346
G TC N+ + C CPPG+S +C+
Sbjct: 1956 CQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDID 2015
Query: 1347 GQVK----CRKGEQCVHTASGPRCFCP-------SPRDCESGCASSPCQ---HGGSCHPQ 1392
V+ C G C +T +C CP S R C+ S C GG C
Sbjct: 2016 ECVEEPEICALG-TCSNTEGSFKCLCPEGFSLSSSGRRCQD-LRMSYCYAKFEGGKCSSP 2073
Query: 1393 RQPPYYSCQCAPPFS----GSRCELYTAPPSTPPATCLSQYC------------------ 1430
+ + +C G CEL T P Q C
Sbjct: 2074 KSRNHSKQECCCALKGEGWGDPCELC----PTEPDEAFRQICPYGSGIIVGPDDSAVDMD 2129
Query: 1431 ----ADKARDGVCDEACNSHACQWD------GGDCSLTMENPWANCSSPLPCWDYINNQC 1480
D + G C S+ C+ G +C T E CS PC N C
Sbjct: 2130 ECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDE-----CSVGNPCG---NGTC 2181
Query: 1481 DELCNTVECLFDNFECQGNSKTCKYDKYCADH 1512
+ EC + G TC+ CA +
Sbjct: 2182 KNVIGGFECTCEEGFEPGPMMTCEDINECAQN 2213
Score = 482 bits (1241), Expect = e-135
Identities = 462/1676 (27%), Positives = 635/1676 (37%), Gaps = 394/1676 (23%)
Query: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFT--GEDCQYSTSHPCFVSRPCLNGGTCHMLS 125
C +C+N +G CRC SGF E+ + C +S G C
Sbjct: 1039 CTHGKCRN--------TIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTP 1090
Query: 126 RDTYECTCQVGFTG-----KECQWTDACLSHPC-ANGSTCTTVANQFSCKCLTGFT---G 176
D +EC C G+ K C D C P G C + C+C G
Sbjct: 1091 GD-FECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
Query: 177 QKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGG-- 234
D+NEC++ H G C+NL G YQC C G+ V +NGG
Sbjct: 1150 ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCE 1209
Query: 235 TCRQTGDFTFECNCLPGFEGSTCER---NIDDC-PNHRCQNGGVCVDGVNTYNCRCPPQW 290
T + ++EC+C PGF +R +ID+C N +GG C + Y C C +
Sbjct: 1210 TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLC---Y 1266
Query: 291 TGQFCTE------DVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSG----DDCSENID 340
G +E DV+EC L PN C + GTC N G + C C G+SG C++ I+
Sbjct: 1267 DGFMASEDMKTCVDVNECDLNPNICLS-GTCENTKGSFICHCDMGYSGKKGKTGCTD-IN 1324
Query: 341 DCAFA--SCTPGSTCIDRVASFSCMCPEG--KAGLLCHLDDACISNPCHKGALCDTNPLN 396
+C +C + C + SF C C G G+ C D C + D
Sbjct: 1325 ECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTM 1384
Query: 397 GQYICTCPQGYKGADCT-EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GP 451
G Y C C +GY G T D+DEC+ N N C + G+C+N G + CEC G+ G
Sbjct: 1385 GSYRCLCKEGYTGDGFTCTDLDECS-ENLNLCGN-GQCLNAPGGYRCECDMGFVPSADGK 1442
Query: 452 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQSNPCVNNG 507
CE DI+EC TC + G F C C G++ G +C ++NEC +G
Sbjct: 1443 ACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNC-TDVNECLDPTTCISG 1500
Query: 508 QCVDKVNRFQCLCPPGF------TGPV------CQIDI---DDCSSTPCLN--------- 543
CV+ + C CPP F G V C +DI D T C N
Sbjct: 1501 NCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKA 1560
Query: 544 ----------GAKCIDHP----NGYECQCATG-------FTGVLCEENIDNCD--PDPCH 580
G C P + Y+ C G T +L E+ID C P C
Sbjct: 1561 SCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVIL--EDIDECQELPGLCQ 1618
Query: 581 HGQCQDGIDSYTCICNPGYM----GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPG 636
G+C + S+ C C GY +C D ++EC + G C + V Y C C P
Sbjct: 1619 GGKCINTFGSFQCRCPTGYYLNEDTRVC-DDVNECETPGICGPGTCYNTVGNYTCICPPD 1677
Query: 637 TSGVNCEINFDDC----------ASNPCIHGICMDGINRYSCVCS--------------- 671
VN N D A N G + + + C CS
Sbjct: 1678 YMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCP 1737
Query: 672 ---------------PGF-----TGQRCNIDIDECASNP--CRKGATCINGVNGFRCICP 709
PGF TG +DIDEC P C G CIN V FRC CP
Sbjct: 1738 IPSTDEFATLCGSQRPGFVIDIYTG--LPVDIDECREIPGVCENG-VCINMVGSFRCECP 1794
Query: 710 EG----------------PHHPSCYSQV----------------------------NEC- 724
G + P C NEC
Sbjct: 1795 VGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQ 1854
Query: 725 -LSNPCIHGNCTGGLSGYKCLCDAGWVGINCE---VDKNECLSNPCQNGGTCDNLVNGYR 780
+ N C HG C + + CLC G+ + + +D NEC + C N GTC N + +
Sbjct: 1855 EIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGN-GTCRNTIGSFN 1913
Query: 781 CTCKKGF--KGYNCQVNIDECAS---NPCLNQGTCFDDISGYTCHCVLPY----TGKNC- 830
C C GF N +++DECAS N C N G C + + + C C Y G+ C
Sbjct: 1914 CRCNHGFILSHNNDCIDVDECASGNGNLCRN-GQCINTVGSFQCQCNEGYEVAPDGRTCV 1972
Query: 831 ---QTVLAP--CSPNPCENAAVCKESPNFESYTCLCAPGW--QGQRCTIDIDECISKP-C 882
+ +L P C+P C+N SY C+C PG+ Q ++C DIDEC+ +P
Sbjct: 1973 DINECLLEPRKCAPGTCQNLD--------GSYRCICPPGYSLQNEKCE-DIDECVEEPEI 2023
Query: 883 MNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQ---NGGSC-----MDGVNTFS 934
G C NT+GS+ C CP GFS D + C GG C +
Sbjct: 2024 CALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQEC 2083
Query: 935 CLCLPG-FTGDKCQ----------------------------TDMNECLSEPCKNGGTCS 965
C L G GD C+ DM+EC G C
Sbjct: 2084 CCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCI 2143
Query: 966 DYVNSYTCKCQAGF--DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS--F 1021
+ SY C+C G+ G C + +EC+ + GTC + I F C C GF
Sbjct: 2144 NTDGSYRCECPFGYILAGNECVDT-DECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMM 2202
Query: 1022 CLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYT----------------GKN------ 1059
+INEC+ +P L CV+ G+Y C CP+GY GK+
Sbjct: 2203 TCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQ 2262
Query: 1060 --CQTLV-----------------------NLCSRSP--CKNKGTCVQKKAESQCLCPSG 1092
C+ L+ N C P C+N G C+ + C C G
Sbjct: 2263 MECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICEN-GRCLNTRGSYTCECNDG 2321
Query: 1093 WAGA------------YC--DVPNVSCDIAASRRGVLVEHLC---------QHSGVCINA 1129
+ + YC +V C I +S R + + C H +C
Sbjct: 2322 FTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQ 2381
Query: 1130 GNTHYCQ-CPLGYTGSYCEEQLDEC--ASNPCQHGATCSDFIGGYRCECVPGY----QGV 1182
G + + CP G +DEC + C++G C + G Y C C GY G
Sbjct: 2382 GTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNG-ECVNDRGSYHCICKTGYTPDITGT 2440
Query: 1183 NCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG----TRGLLCEENIDDCARGPHCLNG 1238
+C +++EC P C + ++CSCP G G C++ +D+CA H
Sbjct: 2441 SC-VDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKD-LDECATKQHNCQ- 2497
Query: 1239 GQCMDRIGGYSCRCLPGFAGERCEG-DINECLS--NPCSSEGSLDCIQLTNDYLCVCRSA 1295
C++ IGG++C+C PGF D NEC S N C S+G C + C C+
Sbjct: 2498 FLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGI--CQNTPGSFTCECQRG 2555
Query: 1296 F----TGRHCETFVDVCP-QMPCLNGGTCAVASNMPDGFICRCPPG----FSGARC--QS 1344
F TG CE VD C C +G N+ G+ C CP G + +C ++
Sbjct: 2556 FSLDQTGSSCED-VDECEGNHRCQHG-----CQNIIGGYRCSCPQGYLQHYQWNQCVDEN 2609
Query: 1345 SCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSC 1400
C G C +T +C CP+ E S CQ C + P Y C
Sbjct: 2610 ECLSAHICGGASCHNTLGSYKCMCPAGFQYEQ--FSGGCQDINECGSAQAPCSYGC 2663
Score = 458 bits (1179), Expect = e-128
Identities = 445/1623 (27%), Positives = 645/1623 (39%), Gaps = 382/1623 (23%)
Query: 109 CFVSRPCLNGGTCHMLSRDTYECTCQVGFT---GKECQWTDACLSHPCANGSTCTTVANQ 165
C + R G C + + + C C GF EC D C +PCA G C
Sbjct: 453 CQLVRYLCQNGRC-IPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGE-CINNQGS 510
Query: 166 FSCKCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC 218
++C+C G+ T D++EC G + G C+N GS+ C C GF G+ C
Sbjct: 511 YTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNC 570
Query: 219 DSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDG 278
+ + + C+NG + G +F+C C PGF+ ++ R D + C+ G+C++G
Sbjct: 571 EDMDECSIRNMCLNGMCINEDG--SFKCICKPGFQLASDGRYCKDI--NECETPGICMNG 626
Query: 279 --VNT---YNCRCPPQWT----GQFCTE------------------------DVDECLLQ 305
VNT Y C C P G+ C + EC
Sbjct: 627 RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCA 686
Query: 306 PNACQNGGTC----ANRNGGYGCVCVNGWSGDDCSENIDDCAF-ASCTPGSTCIDRVASF 360
G C A + Y +C +G +I++CA P C + ++
Sbjct: 687 STEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTY 746
Query: 361 SCMCPEG----KAGLLCHLDDACISNP--CHKGALCDTNPLNGQYICTCPQGY---KGAD 411
C+C G G C + C+ N C G C P G ++CTCP+G+
Sbjct: 747 KCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ-CRNTP--GSFVCTCPKGFIYKPDLK 803
Query: 412 CTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC----------------LKG-----YAG 450
ED+DEC S+PC + G C N+ G+F CEC +KG
Sbjct: 804 TCEDIDEC---ESSPCIN-GVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVID 859
Query: 451 PRCEMDIN--ECHSDPCQNDATCLDKIGGFTC-------LCMPGF---KGVHCELEINEC 498
RCE++IN S C + L G C +C G+ KG CE +I+EC
Sbjct: 860 GRCEININGATLKSQCCSS----LGAAWGSPCTLCQVDPICGKGYSRIKGTQCE-DIDEC 914
Query: 499 QSNPCV-NNGQCVDKVNRFQCLCPPGF----TGPVC------------------------ 529
+ P V NG CV+ F+C CP G TG +C
Sbjct: 915 EVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGR 974
Query: 530 -QIDIDDCSSTPCLNGAKCIDHP----NGYECQCATG--------FTGVLCEENIDNCD- 575
++D CS +C + P YE C G G ++I+ C
Sbjct: 975 HRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKM 1034
Query: 576 -PDPCHHGQCQDGIDSYTCICNPGYM----GAICSDQIDECYSSPCL-NDGRCIDLVNGY 629
P C HG+C++ I S+ C C+ G+ C+D IDEC SP L G+C++ +
Sbjct: 1035 IPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTD-IDECRISPDLCGRGQCVNTPGDF 1093
Query: 630 QCNCQPG-TSGV----NCEINFDDCASNP--CIHGICMDGINRYSCVCSPGF---TGQRC 679
+C C G SG NC ++ D+C +P C G+C + Y C C PG
Sbjct: 1094 ECKCDEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISA 1152
Query: 680 NIDIDEC--ASNPCRKGATCINGVNGFRCICPEGPHHPS----CYSQVNEC-LSNPCIHG 732
IDI+EC +++ C G C+N + ++C C G H C ++EC + N
Sbjct: 1153 CIDINECELSAHLCPNG-RCVNLIGKYQCACNPGYHSTPDRLFCV-DIDECSIMNGGCET 1210
Query: 733 NCTGGLSGYKCLCDAGWVGI----NCEVDKNECLSNP-CQNGGTCDNLVNGYRCTCKKGF 787
CT Y+C C G+ + +C D +EC NP +GG C N+ YRC C GF
Sbjct: 1211 FCTNSEGSYECSCQPGFALMPDQRSC-TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGF 1269
Query: 788 ---KGYNCQVNIDECASNP--CLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCS---- 838
+ V+++EC NP CL+ GTC + + CHC + Y+GK +T +
Sbjct: 1270 MASEDMKTCVDVNECDLNPNICLS-GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEI 1328
Query: 839 -PNPCENAAVCKESPNFESYTCLCAPGW--QGQRCTIDIDECI--SKPCMNHGLCHNTQG 893
+ C AVC + S+ C C+PGW G +CT D+DEC + C H C NT G
Sbjct: 1329 GAHNCGKHAVCTNTAG--SFKCSCSPGWIGDGIKCT-DLDECSNGTHMCSQHADCKNTMG 1385
Query: 894 SYMCECPPGFS--GMDCEEDIDDCL--ANPCQNGGSCMDGVNTFSCLCLPGFT----GDK 945
SY C C G++ G C D+D+C N C N G C++ + C C GF G
Sbjct: 1386 SYRCLCKEGYTGDGFTC-TDLDECSENLNLCGN-GQCLNAPGGYRCECDMGFVPSADGKA 1443
Query: 946 CQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD----GVHCENNINECTESSCFNGGT 1001
C+ D++EC GTC + + C+C+ G++ G +C ++NEC + + G
Sbjct: 1444 CE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNC-TDVNECLDPTTCISGN 1501
Query: 1002 CVDGINSFSCLCPVGF------------TGSFCLHEI---NECSSHPCLNEGTCVDGLGT 1046
CV+ S+ C CP F C +I + C NE G+G
Sbjct: 1502 CVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNE----IGVGV 1557
Query: 1047 YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCD 1106
+ SC GK T +C P N +E + LCP G + + D
Sbjct: 1558 SKASCCCS-LGKAWGTPCEMC---PAVN-------TSEYKILCPGGEGFRPNPITVILED 1606
Query: 1107 IAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECASNPCQHGA 1162
I + + LCQ G CIN + C+CP GY C++ ++EC +
Sbjct: 1607 IDECQE---LPGLCQ-GGKCINTFGSFQCRCPTGYYLNEDTRVCDD-VNECETPGICGPG 1661
Query: 1163 TCSDFIGGYRCECVPGYQGVN--------------------------------------C 1184
TC + +G Y C C P Y VN C
Sbjct: 1662 TCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCC 1721
Query: 1185 EYEVDECQNQPCQ-------------------------------------------NGGT 1201
Y + N+PC+ G
Sbjct: 1722 SYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGV 1781
Query: 1202 CIDLVNHFKCSCPPG---TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF-- 1256
CI++V F+C CP G LL E+ID+C GP C +C++ G Y C C PG+
Sbjct: 1782 CINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRF 1841
Query: 1257 -AGERCEGDINEC--LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF---VDVCPQ 1310
+ +C D NEC + N CS CI + C+C + F +T ++ C +
Sbjct: 1842 TSTGQC-NDRNECQEIPNICSHG---QCIDTVGSFYCLCHTGFKTNDDQTMCLDINECER 1897
Query: 1311 MPCLNGGTCAVASNMPDGFICRCPPGF---------SGARCQSSCGQVKCRKGEQCVHTA 1361
C N GTC N F CRC GF C S G + CR G QC++T
Sbjct: 1898 DACGN-GTC---RNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNL-CRNG-QCINTV 1951
Query: 1362 SGPRCFC-------PSPRDCE--SGCASSPCQHG-GSCHPQRQPPYYSCQCAPPFS--GS 1409
+C C P R C + C P + G+C Q Y C C P +S
Sbjct: 1952 GSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTC--QNLDGSYRCICPPGYSLQNE 2009
Query: 1410 RCE 1412
+CE
Sbjct: 2010 KCE 2012
Score = 424 bits (1091), Expect = e-118
Identities = 395/1450 (27%), Positives = 578/1450 (39%), Gaps = 347/1450 (23%)
Query: 28 CRDGYEPCVNEGMCV--TYHN--GTGYCKCPEGFLGEY----CQHRDPCEKNRCQNGGTC 79
C D E +N +C+ T N G+ C C G+ G+ C + CE G
Sbjct: 1278 CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHA 1337
Query: 80 VAQAMLGKATCRCASGFTGE--------DCQYSTSHPCFVSRPCLNGGTCHMLSRDTYEC 131
V G C C+ G+ G+ +C T H C C N + +Y C
Sbjct: 1338 VCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGT-HMCSQHADCKN-------TMGSYRC 1389
Query: 132 TCQVGFTGK--ECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFT----GQKCETDV 183
C+ G+TG C D C + C NG C + C+C GF G+ CE D+
Sbjct: 1390 LCKEGYTGDGFTCTDLDECSENLNLCGNGQ-CLNAPGGYRCECDMGFVPSADGKACE-DI 1447
Query: 184 NECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTCRQT 239
+EC +P C G TC NLPG ++C+C G+ +G C + P+ C++G
Sbjct: 1448 DECSLPNICVFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTP 1506
Query: 240 GDFTFECNCLPGFEGSTCERNIDDCPNHRC--------QNGGVCVD-----GVNTYNC-- 284
G + C+C P FE + D + C NG GV+ +C
Sbjct: 1507 GSYI--CDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCC 1564
Query: 285 -----------RCPPQWTGQF-----------------CTEDVDECLLQPNACQNGGTCA 316
CP T ++ ED+DEC P CQ GG C
Sbjct: 1565 SLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ-GGKCI 1623
Query: 317 NRNGGYGCVCVNGWSGDDCS---ENIDDCAFAS-CTPGSTCIDRVASFSCMCPEGKAGL- 371
N G + C C G+ ++ + +++++C C PG TC + V +++C+CP +
Sbjct: 1624 NTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPG-TCYNTVGNYTCICPPDYMQVN 1682
Query: 372 -----------LCH---------LDDACISNPCHKGALCDTN--------------PLNG 397
LC+ D + N K C N P
Sbjct: 1683 GGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTD 1742
Query: 398 QYICTCPQGYKG------ADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGP 451
++ C G D+DEC CE+ G C+N G+F CEC G+
Sbjct: 1743 EFATLCGSQRPGFVIDIYTGLPVDIDECREI-PGVCEN-GVCINMVGSFRCECPVGFFYN 1800
Query: 452 R----CEMDINECHSDP-CQNDATCLDKIGGFTCLCMPGFKGV---HCELEINECQSNPC 503
CE DI+EC + P CQ +A C++ G + C C PG++ C + NECQ P
Sbjct: 1801 DKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCN-DRNECQEIPN 1858
Query: 504 V-NNGQCVDKVNRFQCLCPPGFTGPVCQ---IDIDDCSSTPCLNGAKCIDHPNGYECQCA 559
+ ++GQC+D V F CLC GF Q +DI++C C NG C + + C+C
Sbjct: 1859 ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGT-CRNTIGSFNCRCN 1917
Query: 560 TGFTGVLCEEN----IDNC---DPDPCHHGQCQDGIDSYTCICNPGYM----GAICSDQI 608
GF +L N +D C + + C +GQC + + S+ C CN GY G C D I
Sbjct: 1918 HGF--ILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVD-I 1974
Query: 609 DECYSSP--CLNDGRCIDLVNGYQCNCQPGTSGVN--CEINFDDCASNP--CIHGICMDG 662
+EC P C G C +L Y+C C PG S N CE + D+C P C G C +
Sbjct: 1975 NECLLEPRKCA-PGTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICALGTCSNT 2032
Query: 663 INRYSCVCSPGFT----GQRCN----------IDIDECASNPCRKGAT--CINGVNG--- 703
+ C+C GF+ G+RC + +C+S R + C + G
Sbjct: 2033 EGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGW 2092
Query: 704 --------------FRCICPEGPH----HPSCYSQVNECLS-NPCIHGNCTGGLSGYKCL 744
FR ICP G ++EC + C HG C Y+C
Sbjct: 2093 GDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCE 2152
Query: 745 CDAGWV--GINCEVDKNEC-LSNPCQNGGTCDNLVNGYRCTCKKGFKG---YNCQVNIDE 798
C G++ G C VD +EC + NPC NG TC N++ G+ CTC++GF+ C+ +I+E
Sbjct: 2153 CPFGYILAGNEC-VDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCE-DINE 2209
Query: 799 CASNPCLNQGTCFDDISGYTCHCVLPYT----------------GKN--------CQ--- 831
CA NP L C + Y C C + Y GK+ C+
Sbjct: 2210 CAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLI 2269
Query: 832 -TVLAPCSPN--------PCENAAVCKESPNF----------ESYTCLCAPGWQGQRCTI 872
T + C P C + C+ P SYTC C G+
Sbjct: 2270 GTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASP--- 2326
Query: 873 DIDECISKPCMNHGLCHNTQGSYMCE---------------------------------- 898
+ DEC+ G C MC+
Sbjct: 2327 NQDECLDN---REGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGT 2383
Query: 899 ------CPPGFSGMDCEEDIDDC--LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT-- 948
CP G M DID+C + + C+NG C++ ++ C+C G+T D T
Sbjct: 2384 VAFKKLCPHGRGFMTNGADIDECKVIHDVCRNG-ECVNDRGSYHCICKTGYTPDITGTSC 2442
Query: 949 -DMNECLSEPCKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCV 1003
D+NEC P C + SY C C G+ DG C++ ++EC CV
Sbjct: 2443 VDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKD-LDECATKQHNCQFLCV 2501
Query: 1004 DGINSFSCLCPVGFTG--SFCLHEINECSS--HPCLNEGTCVDGLGTYRCSCPLGY---- 1055
+ I F+C CP GFT + C+ NEC+S + C ++G C + G++ C C G+
Sbjct: 2502 NTIGGFTCKCPPGFTQHHTSCIDN-NECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQ 2560
Query: 1056 TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115
TG +C+ + C++ C +C CP G+ Y + L
Sbjct: 2561 TGSSCEDVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHY------QWNQCVDENECL 2612
Query: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASN--PCQHGATCSDFIG 1169
H+C + C N ++ C CP G+ C++ ++EC S PC +G CS+ G
Sbjct: 2613 SAHICGGAS-CHNTLGSYKCMCPAGFQYEQFSGGCQD-INECGSAQAPCSYG--CSNTEG 2668
Query: 1170 GYRCECVPGY 1179
GY C C PGY
Sbjct: 2669 GYLCGCPPGY 2678
Score = 392 bits (1008), Expect = e-108
Identities = 415/1466 (28%), Positives = 591/1466 (40%), Gaps = 315/1466 (21%)
Query: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCE--KNRCQN 75
C PA CR G+ P + G CQ D C+ CQ
Sbjct: 221 CEMCPAQPHPCRRGFIPNIRTGA---------------------CQDVDECQAIPGLCQ- 258
Query: 76 GGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQV 135
GG C+ +G C+C +G H L+
Sbjct: 259 GGNCI--NTVGSFECKCPAG--------------------------HKLNE--------- 281
Query: 136 GFTGKECQWTDACLSHP-CANGSTCTTVANQFSCKCLTGF----TGQKCETDVNECDIPG 190
++C+ D C + P G CT + + CKC GF G +C DV PG
Sbjct: 282 --VSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC-IDVR----PG 334
Query: 191 HCQ---HGGTCLN-LPGS---YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
+C G C N LP S QC C G C S V AP C R T DF
Sbjct: 335 YCYTALTNGRCSNQLPQSITKMQCCCDAG----RCWSPGVTVAPEMC----PIRATEDFN 386
Query: 244 FECN------------------------CLPGFEGSTCERNIDDCPNHRCQNGGVCVDGV 279
C+ PGF P + V+ +
Sbjct: 387 KLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFP-----------PGPQIPVPRPPVEYL 435
Query: 280 NTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSE-- 337
Y R PP+ T D C L CQN G C G C C G+ D E
Sbjct: 436 --YPSREPPRVLPVNVT---DYCQLVRYLCQN-GRCIPTPGSCRCECNKGFQLDLRGECI 489
Query: 338 NIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLL----CHLDDACISNP--CHKGALCD 391
++D+C C G CI+ S++C C G L C D C+ N C+ G +
Sbjct: 490 DVDECEKNPCA-GGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCIN 548
Query: 392 TNPLNGQYICTCPQGY----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKG 447
T +G + C C G+ G +C ED+DEC++ N C + G C+N DG+F C C G
Sbjct: 549 T---DGSFHCVCNAGFHVTRDGKNC-EDMDECSIRNM--CLN-GMCINEDGSFKCICKPG 601
Query: 448 YA----GPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK-GVHCELEINECQSNP 502
+ G C+ DINEC + + C++ G + C C PG G+ + ++ +
Sbjct: 602 FQLASDGRYCK-DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRST 660
Query: 503 C---VNNGQCV----DKVNRFQCLCPP---GFTGPVCQIDIDDCSSTPCLNGAKCIDHPN 552
C GQC+ V + +C C F P C P N A+
Sbjct: 661 CYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEP--------CQPCPAQNSAE------ 706
Query: 553 GYECQCATGFTGVLCEENIDNC--DPDPCHHGQCQDGIDSYTCICNPGY----MGAICSD 606
Y+ C++G +I+ C DPD C +G C++ +Y CICN GY G C D
Sbjct: 707 -YQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVD 765
Query: 607 QIDECYSSPCLND-GRCIDLVNGYQCNCQPG----TSGVNCEINFDDCASNPCIHGICMD 661
I+EC + L D G+C + + C C G CE + D+C S+PCI+G+C +
Sbjct: 766 -INECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE-DIDECESSPCINGVCKN 823
Query: 662 GINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRC-ICPEGPHHPS-CYS 719
+ C CS T +D + KG TC V RC I G S C S
Sbjct: 824 SPGSFICECSSEST-----LDPTKTICIETIKG-TCWQTVIDGRCEININGATLKSQCCS 877
Query: 720 QVNECLSNPC----IHGNCTGGLSGYKCLCDAGWVGINCE-VDKNECLSNPCQNGGTCDN 774
+ +PC + C G S K G CE +D+ E C+N G C N
Sbjct: 878 SLGAAWGSPCTLCQVDPICGKGYSRIK--------GTQCEDIDECEVFPGVCKN-GLCVN 928
Query: 775 LVNGYRCTCKKGFKGYNCQVNIDECASNPCLN--QGTCFDDISGYTCHCVLPYTGKN--- 829
++C C G + +D CL+ TCF + C LP G++
Sbjct: 929 TRGSFKCQCPSG-------MTLD-ATGRICLDIRLETCF--LRYEDEECTLPIAGRHRMD 978
Query: 830 --CQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCT------IDIDECISKP 881
C +V A CE + + +P +E C PG+ + T DI+EC P
Sbjct: 979 ACCCSVGAAWGTEECEECPM-RNTPEYEE-LCPRGPGFATKEITNGKPFFKDINECKMIP 1036
Query: 882 CM-NHGLCHNTQGSYMCECPPGFSGMDCEE----DIDDCLANPCQNG-GSCMDGVNTFSC 935
+ HG C NT GS+ C C GF+ +D EE DID+C +P G G C++ F C
Sbjct: 1037 SLCTHGKCRNTIGSFKCRCDSGFA-LDSEERNCTDIDECRISPDLCGRGQCVNTPGDFEC 1095
Query: 936 LCLPGFTGD----KCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGFD---GVHCEN 986
C G+ K D++EC +P C+ GG C + SY C+C G +
Sbjct: 1096 KCDEGYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQLSPNISACI 1154
Query: 987 NINECTESS--CFNGGTCVDGINSFSCLCPVGFTGS----FCLHEINECSSHPCLNEGTC 1040
+INEC S+ C N G CV+ I + C C G+ + FC+ +I+ECS E C
Sbjct: 1155 DINECELSAHLCPN-GRCVNLIGKYQCACNPGYHSTPDRLFCV-DIDECSIMNGGCETFC 1212
Query: 1041 VDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSP-CKNKGTCVQKKAESQCLCPSGWAG 1095
+ G+Y CSC G+ ++C T ++ C +P + G C E +CLC G+
Sbjct: 1213 TNSEGSYECSCQPGFALMPDQRSC-TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMA 1271
Query: 1096 A----YCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE---E 1148
+ C N CD L ++C SG C N + C C +GY+G +
Sbjct: 1272 SEDMKTCVDVN-ECD--------LNPNICL-SGTCENTKGSFICHCDMGYSGKKGKTGCT 1321
Query: 1149 QLDEC--ASNPCQHGATCSDFIGGYRCECVPGY--QGVNCEYEVDECQN--QPCQNGGTC 1202
++EC ++ C A C++ G ++C C PG+ G+ C ++DEC N C C
Sbjct: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCT-DLDECSNGTHMCSQHADC 1380
Query: 1203 IDLVNHFKCSCPPGTR--GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA--- 1257
+ + ++C C G G C + +D+C+ + GQC++ GGY C C GF
Sbjct: 1381 KNTMGSYRCLCKEGYTGDGFTCTD-LDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSA 1439
Query: 1258 -GERCEGDINEC-LSNPCSSEGSLDCIQLTNDYLCVCRSAF----TGRHCETFVDVCPQM 1311
G+ CE DI+EC L N C C L + C C + +G +C T V+ C
Sbjct: 1440 DGKACE-DIDECSLPNICVFG---TCHNLPGLFRCECEIGYELDRSGGNC-TDVNECLDP 1494
Query: 1312 PCLNGGTCAVASNMPDGFICRCPPGF 1337
G C N P +IC CPP F
Sbjct: 1495 TTCISGNCV---NTPGSYICDCPPDF 1517
Score = 285 bits (730), Expect = 3e-76
Identities = 349/1381 (25%), Positives = 497/1381 (35%), Gaps = 337/1381 (24%)
Query: 307 NACQNGGTCANRNGGYGCVCVNGWS----GDDCSENIDDCAFASCTPGSTCIDRVASFSC 362
+A + C +R Y C GW G+ C I C SC G + C
Sbjct: 51 DALKGPNVCGSR---YNAYCCPGWKTLPGGNQCIVPI--CRH-SCGDGFCSRPNM----C 100
Query: 363 MCPEGKAGLLCHLDDACISN-PCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAM 421
CP G+ C N C G C + C C +GY G C + V E
Sbjct: 101 TCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDH------CLCQKGYIGTHCGQPVCESG- 153
Query: 422 ANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCL 481
C + G+CV + C C G+ GP+CE D ++ C ++ G C
Sbjct: 154 -----CLNGGRCVAPN---RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCT 205
Query: 482 CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC 541
C + +PC C + + + P CQ D+D+C + P
Sbjct: 206 ------KTLCCATVGRAWGHPCE---MCPAQPHPCRRGFIPNIRTGACQ-DVDECQAIPG 255
Query: 542 L-NGAKCIDHPNGYECQCATGF----TGVLCEENIDNCDPDP--CHHGQCQDGIDSYTCI 594
L G CI+ +EC+C G CE+ ID C P C G+C + + SY C
Sbjct: 256 LCQGGNCINTVGSFECKCPAGHKLNEVSQKCED-IDECSTIPGICEGGECTNTVSSYFCK 314
Query: 595 CNPGYM----GAICSDQIDECYSSPCLNDGRCID----LVNGYQCNCQPG---TSGVN-- 641
C PG+ G C D + Y L +GRC + + QC C G + GV
Sbjct: 315 CPPGFYTSPDGTRCID-VRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVA 373
Query: 642 ---CEINFDDCASNPCIHGICMDGINRYS----------CVCSPGF-TGQRCNI------ 681
C I + + C + + G Y PGF G + +
Sbjct: 374 PEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVE 433
Query: 682 -----------------DIDECASNPCRKGATCINGVNGFRCICPEG---PHHPSCYSQV 721
D + C+ G CI RC C +G C V
Sbjct: 434 YLYPSREPPRVLPVNVTDYCQLVRYLCQNG-RCIPTPGSCRCECNKGFQLDLRGECI-DV 491
Query: 722 NECLSNPCIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNECLSN-PCQNGGTCDNLV 776
+EC NPC G C Y C C AG+ C D +ECL N N G C N
Sbjct: 492 DECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECR-DIDECLQNGRICNNGRCINTD 550
Query: 777 NGYRCTCKKGF----KGYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHC----VLPYTG 827
+ C C GF G NC+ ++DEC+ N CLN G C ++ + C C L G
Sbjct: 551 GSFHCVCNAGFHVTRDGKNCE-DMDECSIRNMCLN-GMCINEDGSFKCICKPGFQLASDG 608
Query: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGL 887
+ C+ + N CE +C +G
Sbjct: 609 RYCKDI------NECETPGICM-----------------------------------NGR 627
Query: 888 CHNTQGSYMCECPPGFS-GMDCEEDIDDCLANPCQNG---GSCM----DGVNTFSCLCLP 939
C NT GSY CEC PG + G+D +D + + C G G C+ V C C
Sbjct: 628 CVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCAS 687
Query: 940 G--FTGDKCQ------------------------TDMNECLSEP--CKNGGTCSDYVNSY 971
G+ CQ +D+NEC +P C N G C + +Y
Sbjct: 688 TEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN-GICENLRGTY 746
Query: 972 TCKCQAGFD----GVHCENNINECTESSCF-NGGTCVDGINSFSCLCPVGFTGSFCL--- 1023
C C +G++ G +C +INEC +S + G C + SF C CP GF L
Sbjct: 747 KCICNSGYEVDSTGKNCV-DINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTC 805
Query: 1024 HEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ--- 1080
+I+EC S PC+N G C + G++ C C T +T +C + KGTC Q
Sbjct: 806 EDIDECESSPCIN-GVCKNSPGSFICECSSESTLDPTKT---ICIET---IKGTCWQTVI 858
Query: 1081 ----------KKAESQCLCPSGWA-GAYCDVPNVS--CDIAASR-RGVLVEHL--CQ--- 1121
+SQC G A G+ C + V C SR +G E + C+
Sbjct: 859 DGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFP 918
Query: 1122 ---HSGVCINAGNTHYCQCPLGY----TGSYC-EEQLDECASNPCQHGATCSDFIGGYR- 1172
+G+C+N + CQCP G TG C + +L+ C C+ I G
Sbjct: 919 GVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLR--YEDEECTLPIAGRHR 976
Query: 1173 ---CECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG--------TRGLL 1221
C C V + +EC+ P +N ++ CP G T G
Sbjct: 977 MDACCC-----SVGAAWGTEECEECPMRN-------TPEYEELCPRGPGFATKEITNGKP 1024
Query: 1222 CEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA---GERCEGDINECLSNPCSSEGS 1278
++I++C P G+C + IG + CRC GFA ER DI+EC +P G
Sbjct: 1025 FFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISP-DLCGR 1083
Query: 1279 LDCIQLTNDYLCVCRSAFTG-----RHCETFVDVCPQMPCL-NGGTCAVASNMPDGFICR 1332
C+ D+ C C + ++C +D C + P L GG C N + C
Sbjct: 1084 GQCVNTPGDFECKCDEGYESGFMMMKNCMD-IDECQRDPLLCRGGVC---HNTEGSYRCE 1139
Query: 1333 CPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQ 1392
CPPG + S+C + + E H RC +
Sbjct: 1140 CPPGHQLSPNISAC--IDINECELSAHLCPNGRCVNLIGK-------------------- 1177
Query: 1393 RQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDG 1452
Y C C P + STP +C D + + C + +G
Sbjct: 1178 -----YQCACNPGYH-----------STPDRL----FCVDIDECSIMNGGCETFCTNSEG 1217
Query: 1453 G-DCS----LTMENPWANCSSPLPCWDYIN----NQCDELCNTVECL-FDNFECQGNSKT 1502
+CS + +C+ C D N QC + CL +D F + KT
Sbjct: 1218 SYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKT 1277
Query: 1503 C 1503
C
Sbjct: 1278 C 1278
Score = 132 bits (333), Expect = 3e-30
Identities = 129/467 (27%), Positives = 178/467 (38%), Gaps = 86/467 (18%)
Query: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFL----GEYCQHRDPCEKNR--CQNGGTCV 80
+C +G C + M GT C C G+ GE C + C+ C+NG
Sbjct: 2250 ECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLN 2309
Query: 81 AQAMLGKATCRCASGFTGED---------------------CQYSTSH--PCFVSRPCLN 117
+ G TC C GFT CQ +S+ P S C +
Sbjct: 2310 TR---GSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCD 2366
Query: 118 GGT--------CHMLSRDTYECTCQVG--FTGKECQWTDACLSHPCANGSTCTTVANQFS 167
GG C ++ C G F + + H C +
Sbjct: 2367 GGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYH 2426
Query: 168 CKCLTGFT----GQKCETDVNECD-IPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYC 218
C C TG+T G C D+NEC+ P C C N GSYQC CP+G+ G+ C
Sbjct: 2427 CICKTGYTPDITGTSC-VDLNECNQAPKPCNF--ICKNTEGSYQCSCPKGYILQEDGRSC 2483
Query: 219 DSLYVPCAPSPCVNGGTCRQT-GDFTFECNCLPGF--EGSTCERNIDDCPN--HRCQNGG 273
L CA C T G FT C C PGF ++C N ++C + + C + G
Sbjct: 2484 KDLD-ECATKQHNCQFLCVNTIGGFT--CKCPPGFTQHHTSCIDN-NECTSDINLCGSKG 2539
Query: 274 VCVDGVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNG 329
+C + ++ C C + TG C EDVDEC + CQ+G C N GGY C C G
Sbjct: 2540 ICQNTPGSFTCECQRGFSLDQTGSSC-EDVDECEGN-HRCQHG--CQNIIGGYRCSCPQG 2595
Query: 330 W----SGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEG------KAGLLCHLDDAC 379
+ + C + ++C A G++C + + S+ CMCP G G +
Sbjct: 2596 YLQHYQWNQCVDE-NECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGS 2654
Query: 380 ISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNP 426
PC G + G Y+C CP GY V M NP
Sbjct: 2655 AQAPCSYGC----SNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNP 2697
Score = 102 bits (253), Expect = 6e-21
Identities = 88/291 (30%), Positives = 119/291 (40%), Gaps = 58/291 (19%)
Query: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
C+N G C H C C +G++G +C P ++ C NGG CVA C C
Sbjct: 123 CMNGGSCSDDH-----CLCQKGYIGTHCGQ--PVCESGCLNGGRCVAPNR-----CACTY 170
Query: 95 GFTGEDCQ--YSTSHPCF--VSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLS 150
GFTG C+ Y T PCF +S G ++ T C G C+ A
Sbjct: 171 GFTGPQCERDYRTG-PCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPA-QP 228
Query: 151 HPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECD-IPGHCQHGGTCLNLPGSYQCQC 209
HPC G F TG C+ DV+EC IPG CQ GG C+N GS++C+C
Sbjct: 229 HPCRRG---------FIPNIRTG----ACQ-DVDECQAIPGLCQ-GGNCINTVGSFECKC 273
Query: 210 PQGF----TGQYCDSLYVPCAPSPCV-NGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC 264
P G Q C+ + C+ P + GG C T F C C PGF
Sbjct: 274 PAGHKLNEVSQKCEDI-DECSTIPGICEGGECTNTVSSYF-CKCPPGF------------ 319
Query: 265 PNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC 315
+ +G C+D Y C T C+ + + + + C + G C
Sbjct: 320 --YTSPDGTRCIDVRPGY---CYTALTNGRCSNQLPQSITKMQCCCDAGRC 365
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 508 bits (1308), Expect = e-143
Identities = 457/1625 (28%), Positives = 668/1625 (41%), Gaps = 331/1625 (20%)
Query: 26 LQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPC--------EKNRCQNGG 77
L CR G CVN G+ C CP G E R+ C N C+NG
Sbjct: 1167 LLCRGG--TCVNT-------EGSFQCDCPLGH--ELSPSREDCVDINECSLSDNLCRNG- 1214
Query: 78 TCVAQAMLGKATCRCASGFTGE-DCQYSTS-HPCFVSRPCLNGG--TCHMLSRDTYECTC 133
CV M+G C C G+ D Q T C + +NGG T S +YEC+C
Sbjct: 1215 KCVN--MIGTYQCSCNPGYQATPDRQGCTDIDECMI----MNGGCDTQCTNSEGSYECSC 1268
Query: 134 QVGFT----GKECQWTDACLSHP-CANGSTCTTVANQFSCKCLTGFTGQ---KCETDVNE 185
G+ G+ C D C ++P +G CT + ++ C C GF K DVNE
Sbjct: 1269 SEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNE 1328
Query: 186 CDIPGHCQHGGTCLNLPGSYQCQCPQGF-----TGQYCDSLYVPCAPSPCVNGGTCRQTG 240
CD+ + G C N GS+ C C G+ T D C +C
Sbjct: 1329 CDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIP 1388
Query: 241 DFTFECNCLPGFEGSTCER-NIDDCPN--HRCQNGGVCVDGVNTYNCRCPPQWTGQ-FCT 296
+F+C+C G+ G+ + ++D+C N H+C CV+ +Y C C +TG F
Sbjct: 1389 G-SFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTC 1447
Query: 297 EDVDECLLQPNACQNG----------------------------------------GTCA 316
DVDEC N C+NG GTC
Sbjct: 1448 SDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCN 1507
Query: 317 NRNGGYGCVCVNGW----SGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCP------- 365
N G + C+C +G+ +G +C++ ID+CA C++ + C CP
Sbjct: 1508 NLPGMFHCICDDGYELDRTGGNCTD-IDECADPINCVNGLCVNTPGRYECNCPPDFQLNP 1566
Query: 366 -------------------EGKAGLLCHLD--------DACISNPCHKGALCDT-NPLNG 397
G L C+ + C S G C+T P+N
Sbjct: 1567 TGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNS 1626
Query: 398 -QYICTCP--QGYKGADCT---EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY--- 448
+Y CP +G++ T ED+DEC C+ G C+NT G+F CEC +GY
Sbjct: 1627 TEYYTLCPGGEGFRPNPITIILEDIDECQEL-PGLCQ-GGNCINTFGSFQCECPQGYYLS 1684
Query: 449 AGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGF---KGVHCELEINECQSNPC 503
R DI+EC + P C TC + +G +TC+C P + G H +++ +
Sbjct: 1685 EDTRICEDIDECFAHPGVC-GPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRS 1743
Query: 504 VNNGQCVDK----VNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCA 559
N C ++ V + C C G + C + + + G+
Sbjct: 1744 YNGTTCENELPFNVTKRMCCCTYN-VGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIH 1802
Query: 560 TGFTGVLCEENIDNCDPDP--CHHGQCQDGIDSYTCICNPGY----MGAICSDQIDECYS 613
TG +ID C P C +G C + I S+ C C G+ + +C D IDEC +
Sbjct: 1803 TGKA-----VDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCED-IDECSN 1856
Query: 614 SP--CLNDGRCIDLVNGYQCNCQPG--TSGVNCEINFDDCASNP--CIHGICMDGINRYS 667
C + CI+ Y+C C G S ++ ++C P C HG+C+D Y
Sbjct: 1857 GDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQ 1916
Query: 668 CVCSPGFTG---QRCNIDIDECASNPCRKGATCINGVNGFRCICPEG---PHHPSCYSQV 721
C+C GF Q +D+DEC +PC G TC N V + C+C G H+ C +
Sbjct: 1917 CICHNGFKASQDQTMCMDVDECERHPCGNG-TCKNTVGSYNCLCYPGFELTHNNDCLD-I 1974
Query: 722 NECLS---NPCIHGNCTGGLSGYKCLCDAGWV----GINCEVDKNECLSNPCQ-NGGTCD 773
+EC S C +G C + +KCLC+ G+ G NC +D NEC++ P + GTC
Sbjct: 1975 DECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQ 2033
Query: 774 NLVNGYRCTCKKGF--KGYNCQVNIDECASNP--CLNQGTCFDDISGYTCHC----VLPY 825
NL +RC C G+ K NC ++I+EC +P CL G+C + G+ C C VL
Sbjct: 2034 NLEGSFRCICPPGYEVKSENC-IDINECDEDPNICLF-GSCTNTPGGFQCLCPPGFVLSD 2091
Query: 826 TGKNC-QTVLAPCSPNPCENAAVCKESPNFESYTCLCAP----GWQGQRCTI-------- 872
G+ C T + C N ++ N C C+ GW G C +
Sbjct: 2092 NGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGW-GDPCELCPKDDEVA 2150
Query: 873 --------------------DIDECISKP--CMNHGLCHNTQGSYMCECPPGFS----GM 906
D++EC+ P C N G C NT GS+ CECP G++ G+
Sbjct: 2151 FQDLCPYGHGTVPSLHDTREDVNECLESPGICSN-GQCINTDGSFRCECPMGYNLDYTGV 2209
Query: 907 DCEEDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT--DMNECLSEPCKNGGT 963
C D D+C + NPC NG +C + + +F C C GF D+NEC P
Sbjct: 2210 RCV-DTDECSIGNPCGNG-TCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFR 2267
Query: 964 CSDYVNSYTCKCQAGF----DGVHCENNINECTES--SCFNGGT-CVDGINSFSCLCPVG 1016
C + SY C C G+ D C++ ++EC E C + G C + I +F C+CP G
Sbjct: 2268 CMNTFGSYECTCPIGYALREDQKMCKD-LDECAEGLHDCESRGMMCKNLIGTFMCICPPG 2326
Query: 1017 FT----GSFCLHEINECSSHPCLNE-GTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSP 1071
G C+ E NEC + P + E G CV+ +G+YRC C G+ + T
Sbjct: 2327 MARRPDGEGCVDE-NECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGT--------- 2376
Query: 1072 CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGN 1131
C+ + Q LC + +V C +A+S R ++ + C G G
Sbjct: 2377 -----ECLDNR---QGLC-------FAEVLQTICQMASSSRNLVTKSECCCDG---GRGW 2418
Query: 1132 THYCQ-CPLGYTGSYCE------------EQLDECASNP--CQHGATCSDFIGGYRCECV 1176
H C+ CPL T Y + +DEC P C +G C + +G +RC C
Sbjct: 2419 GHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQ-CINTMGSFRCFCK 2477
Query: 1177 PGY----QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG----TRGLLCEENIDD 1228
GY G +C ++DEC P C + ++CSCP G G C++ +D+
Sbjct: 2478 VGYTTDISGTSC-IDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKD-LDE 2535
Query: 1229 CARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG-DINECLSNP--CSSEGSLDCIQLT 1285
C H C++ +GG++C+C PGF D NEC S P C ++G C
Sbjct: 2536 CQTKQHNCQF-LCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGI--CQNTP 2592
Query: 1286 NDYLCVCRSAF----TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF---- 1337
+ C C+ F TG +CE + C +G N+ G+ C CP G+
Sbjct: 2593 GSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHG-----CQNILGGYRCGCPQGYIQHY 2647
Query: 1338 SGARC--QSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQP 1395
+C ++ C C +T +C CPS + SS C C + P
Sbjct: 2648 QWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQ--FSSACHDVNECSSSKNP 2705
Query: 1396 PYYSC 1400
Y C
Sbjct: 2706 CNYGC 2710
Score = 489 bits (1259), Expect = e-137
Identities = 429/1425 (30%), Positives = 603/1425 (42%), Gaps = 264/1425 (18%)
Query: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE--YCQHRDPCEK--NRCQNGGTCVAQ 82
+C G C C+ G+ C C EG++G C D C ++C CV
Sbjct: 1370 ECEIGAHNCDMHASCLNIP-GSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNT 1428
Query: 83 AMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT---- 138
G C C+ GFTG+ S C + G C + Y C C++GFT
Sbjct: 1429 P--GSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVP-GAYRCECEMGFTPASD 1485
Query: 139 GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGF----TGQKCETDVNECDIPGHCQH 194
+ CQ D C TC + F C C G+ TG C TD++EC P +C +
Sbjct: 1486 SRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADPINCVN 1544
Query: 195 GGTCLNLPGSYQCQCPQGF----TGQYC-----DSLYVPCAP------------------ 227
G C+N PG Y+C CP F TG C + Y+ P
Sbjct: 1545 G-LCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSR 1603
Query: 228 -SPCVNGG--------TCRQTGDFTFECNCLPGFEG------STCERNIDDCPN--HRCQ 270
S C + G TC + C PG EG + +ID+C CQ
Sbjct: 1604 SSCCCSLGKAWGNPCETCPPVNSTEYYTLC-PGGEGFRPNPITIILEDIDECQELPGLCQ 1662
Query: 271 NGGVCVDGVNTYNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVC 326
GG C++ ++ C CP + + C ED+DEC P C GTC N G Y C+C
Sbjct: 1663 -GGNCINTFGSFQCECPQGYYLSEDTRIC-EDIDECFAHPGVC-GPGTCYNTLGNYTCIC 1719
Query: 327 ------VNGWSGDDCSENIDDCAFASCTPGSTCIDR----VASFSCMCPE--GKAGLLCH 374
VNG G +C + + S G+TC + V C C GKA
Sbjct: 1720 PPEYMQVNG--GHNCMDMRKSFCYRSYN-GTTCENELPFNVTKRMCCCTYNVGKAW---- 1772
Query: 375 LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCV 434
+ C PC D + G + G D+DEC C + G C+
Sbjct: 1773 -NKPC--EPCPTPGTADFKTICGNIPGFTFDIHTGK--AVDIDECKEI-PGICAN-GVCI 1825
Query: 435 NTDGAFHCECLKGYAGPR----CEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFK- 487
N G+F CEC G++ CE DI+EC + CQ +A C++ G + C C GFK
Sbjct: 1826 NQIGSFRCECPTGFSYNDLLLVCE-DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKL 1884
Query: 488 --GVHCELEINECQSNPCV-NNGQCVDKVNRFQCLCPPGFTGPVCQ---IDIDDCSSTPC 541
C ++ NEC P V ++G CVD +QC+C GF Q +D+D+C PC
Sbjct: 1885 SPNGAC-VDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPC 1943
Query: 542 LNGAKCIDHPNGYECQCATGFTGVLCEEN----IDNCDP---DPCHHGQCQDGIDSYTCI 594
NG C + Y C C GF L N ID C C +G+C + I S+ C+
Sbjct: 1944 GNGT-CKNTVGSYNCLCYPGFE--LTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCL 2000
Query: 595 CNPGYM----GAICSDQIDECYSSP-CLNDGRCIDLVNGYQCNCQPG--TSGVNCEINFD 647
CN GY G C D +EC + P + G C +L ++C C PG NC I+ +
Sbjct: 2001 CNEGYELTPDGKNCIDT-NECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENC-IDIN 2058
Query: 648 DCASNP--CIHGICMDGINRYSCVCSPGFT----GQRC----------NIDIDECASNPC 691
+C +P C+ G C + + C+C PGF G+RC N + +C+
Sbjct: 2059 ECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKA 2118
Query: 692 ---RKGATCINGVNG-----------------FRCICPEG----PHHPSCYSQVNECLSN 727
K C + + G F+ +CP G P VNECL +
Sbjct: 2119 FNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLES 2178
Query: 728 P--CIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNEC-LSNPCQNGGTCDNLVNGYR 780
P C +G C ++C C G+ G+ C VD +EC + NPC NG TC N++ +
Sbjct: 2179 PGICSNGQCINTDGSFRCECPMGYNLDYTGVRC-VDTDECSIGNPCGNG-TCTNVIGSFE 2236
Query: 781 CTCKKGFKG---YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTV---L 834
C C +GF+ NC+ +I+ECA NP L C + Y C C + Y + Q + L
Sbjct: 2237 CNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDL 2295
Query: 835 APCSP--NPCENAAV-CKESPNFESYTCLCAPGW----QGQRCTIDIDECISKP--CMNH 885
C+ + CE+ + CK ++ C+C PG G+ C +D +EC +KP C N
Sbjct: 2296 DECAEGLHDCESRGMMCKNL--IGTFMCICPPGMARRPDGEGC-VDENECRTKPGICEN- 2351
Query: 886 GLCHNTQGSYMCECPPGF----SGMDCEED-----IDDCLANPCQNGGSCMDGVNTFSCL 936
G C N GSY CEC GF SG +C ++ + L CQ S + V C
Sbjct: 2352 GRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECC 2411
Query: 937 CLPGFT-GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECT--E 993
C G G +C E C GT Y C G +I+EC
Sbjct: 2412 CDGGRGWGHQC---------ELCPLPGTAQ-----YKKICPHGPGYTTDGRDIDECKVMP 2457
Query: 994 SSCFNGGTCVDGINSFSCLCPVGFT----GSFCLHEINECSSHPCLNEGTCVDGLGTYRC 1049
+ C NG C++ + SF C C VG+T G+ C+ +++ECS P C + G+Y+C
Sbjct: 2458 NLCTNG-QCINTMGSFRCFCKVGYTTDISGTSCI-DLDECSQSPKPCNYICKNTEGSYQC 2515
Query: 1050 SCPLGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCD-VPNVS 1104
SCP GY GK C+ L + C + CV C CP G+ + + N
Sbjct: 2516 SCPRGYVLQEDGKTCKDL-DECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNE 2574
Query: 1105 CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECASNP-CQ 1159
C S LC G+C N + C+C G+ TG CE+ +DEC N CQ
Sbjct: 2575 CGSQPS--------LCGAKGICQNTPGSFSCECQRGFSLDATGLNCED-VDECDGNHRCQ 2625
Query: 1160 HGATCSDFIGGYRCECVPGY----QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPP 1215
HG C + +GGYRC C GY Q C E +EC N +C + + +KC+CP
Sbjct: 2626 HG--CQNILGGYRCGCPQGYIQHYQWNQCVDE-NECSNPNACGSASCYNTLGSYKCACPS 2682
Query: 1216 GTR----GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256
G C + +++C+ + N G C + GGY C C PG+
Sbjct: 2683 GFSFDQFSSACHD-VNECSSSKNPCNYG-CSNTEGGYLCGCPPGY 2725
Score = 476 bits (1226), Expect = e-134
Identities = 503/1828 (27%), Positives = 723/1828 (39%), Gaps = 398/1828 (21%)
Query: 23 AHALQCRDGYEP------CVNEGMCVTYH-----------NGTGYCKCPEGFL----GEY 61
++ C GYEP C++ C+ G+ C CP G++ E
Sbjct: 790 SYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETET 849
Query: 62 CQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTC 121
C+ + CE N C NG + LG C C+ G ST C S GTC
Sbjct: 850 CEDINECESNPCVNGA---CRNNLGSFNCECSPGSKLS----STGLICIDSLK----GTC 898
Query: 122 HMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC-KCLTGFTGQKCE 180
+ +D+ C+V G + ++ C + A GS C +C + L G CE
Sbjct: 899 WLNIQDS---RCEVNINGATLK-SECCATLGAAWGSPCERCELDTACPRGLARIKGVTCE 954
Query: 181 TDVNECDI-PGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-----DSLYVPCAPSPC 230
DVNEC++ PG C +G C+N GS+ C+CP+G TG+ C + Y+ C
Sbjct: 955 -DVNECEVFPGVCPNG-RCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDEC 1012
Query: 231 VN------------------GGT----CRQTGDFTFECNCLPG---------FEGSTCER 259
++ GT C + G +E C G G +
Sbjct: 1013 IHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYK 1072
Query: 260 NIDDCPNH--RCQNGGVCVDGVNTYNCRCPPQWT----GQFCTEDVDECLLQPNACQNGG 313
+I++C C G C + + ++ CRC + + CT D+DEC + P+ C G
Sbjct: 1073 DINECKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEERNCT-DIDECRISPDLC-GSG 1129
Query: 314 TCANRNGGYGCVCVNGW-SGDDCSENIDDCAFASCTP----GSTCIDRVASFSCMCPEGK 368
C N G + C C G+ SG +N D P G TC++ SF C CP G
Sbjct: 1130 ICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGH 1189
Query: 369 AGLLCHLDDACISNPCH-KGALCDTNP---LNGQYICTCPQGYKGA----DCTEDVDECA 420
L +D N C LC + G Y C+C GY+ CT D+DEC
Sbjct: 1190 E-LSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCT-DIDECM 1247
Query: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDPCQND-ATCLDKI 475
+ N C+ +C N++G++ C C +GYA G C DI+EC ++P D C +
Sbjct: 1248 IMNGG-CD--TQCTNSEGSYECSCSEGYALMPDGRSC-ADIDECENNPDICDGGQCTNIP 1303
Query: 476 GGFTCLCMPGFKG---VHCELEINEC--QSNPCVNNGQCVDKVNRFQCLCPPGFT---GP 527
G + CLC GF + +++NEC SN C+ G+C + F C C G++ G
Sbjct: 1304 GEYRCLCYDGFMASMDMKTCIDVNECDLNSNICM-FGECENTKGSFICHCQLGYSVKKGT 1362
Query: 528 VCQIDIDDC--SSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG--- 582
D+D+C + C A C++ P ++C C G+ G I D D C +G
Sbjct: 1363 TGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIG----NGIKCIDLDECSNGTHQ 1418
Query: 583 -----QCQDGIDSYTCICNPGYM--GAICSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQ 634
QC + SY C C+ G+ G CSD +DEC + L +G+C+++ Y+C C+
Sbjct: 1419 CSINAQCVNTPGSYRCACSEGFTGDGFTCSD-VDECAENINLCENGQCLNVPGAYRCECE 1477
Query: 635 ----PGTSGVNCEINFDDCA-SNPCIHGICMDGINRYSCVCSPGF----TGQRCNIDIDE 685
P + +C+ + D+C+ N C+ G C + + C+C G+ TG C DIDE
Sbjct: 1478 MGFTPASDSRSCQ-DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCT-DIDE 1535
Query: 686 CASNPCRKGATCINGVNGFRCICPE----GPHHPSCY-SQVNECLSNPCIHG----NCTG 736
CA C+N + C CP P C ++V C G +C
Sbjct: 1536 CADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNT 1595
Query: 737 ----GLSGYKCLCDAG--WVGINCEV-----------------------------DKNEC 761
G+S C C G W G CE D +EC
Sbjct: 1596 EIGVGVSRSSCCCSLGKAW-GNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDEC 1654
Query: 762 LSNP--CQNGGTCDNLVNGYRCTCKKGF---KGYNCQVNIDECASNP-CLNQGTCFDDIS 815
P CQ GG C N ++C C +G+ + +IDEC ++P GTC++ +
Sbjct: 1655 QELPGLCQ-GGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLG 1713
Query: 816 GYTC---------------------HCVLPYTGKNCQTVL--------APCSPN------ 840
YTC C Y G C+ L C+ N
Sbjct: 1714 NYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWN 1773
Query: 841 -PCENAAVCKESPNFESYTCLCA--PGWQGQRCT---IDIDECISKP--CMNHGLCHNTQ 892
PCE +P + +C PG+ T +DIDEC P C N G+C N
Sbjct: 1774 KPCEPC----PTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICAN-GVCINQI 1828
Query: 893 GSYMCECPPGFSGMD----CEEDIDDCL--ANPCQNGGSCMDGVNTFSCLCLPGF--TGD 944
GS+ CECP GFS D C EDID+C N CQ C++ ++ C C GF + +
Sbjct: 1829 GSFRCECPTGFSYNDLLLVC-EDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPN 1887
Query: 945 KCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINECTESSCFN 998
D NECL P C + G C D SY C C GF D C +++EC C N
Sbjct: 1888 GACVDRNECLEIPNVCSH-GLCVDLQGSYQCICHNGFKASQDQTMC-MDVDECERHPCGN 1945
Query: 999 GGTCVDGINSFSCLCPVGFT---GSFCLHEINECSS---HPCLNEGTCVDGLGTYRCSCP 1052
GTC + + S++CLC GF + CL +I+ECSS C N G C + +G+++C C
Sbjct: 1946 -GTCKNTVGSYNCLCYPGFELTHNNDCL-DIDECSSFFGQVCRN-GRCFNEIGSFKCLCN 2002
Query: 1053 LGY----TGKNCQTLVNLCSRSPCK-NKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC-D 1106
GY GKNC N C P + GTC + +C+CP G+ +V + +C D
Sbjct: 2003 EGYELTPDGKNCID-TNECVALPGSCSPGTCQNLEGSFRCICPPGY-----EVKSENCID 2056
Query: 1107 IAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT------------GSYCEEQLD--E 1152
I ++C G C N C CP G+ S+C + +
Sbjct: 2057 INECDED---PNICLF-GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGK 2112
Query: 1153 C----ASNPCQHGATCSDFIG---GYRCECVP-----GYQGVNCEY-------------E 1187
C A N + CS G G CE P +Q + C Y +
Sbjct: 2113 CSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDL-CPYGHGTVPSLHDTRED 2171
Query: 1188 VDECQNQP--CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGPHCLNGGQC 1241
V+EC P C N G CI+ F+C CP G G+ C + D+C+ G C N G C
Sbjct: 2172 VNECLESPGICSN-GQCINTDGSFRCECPMGYNLDYTGVRCVDT-DECSIGNPCGN-GTC 2228
Query: 1242 MDRIGGYSCRCLPGFAG---ERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG 1298
+ IG + C C GF CE DINEC NP + C+ Y C C +
Sbjct: 2229 TNVIGSFECNCNEGFEPGPMMNCE-DINECAQNPLLC--AFRCMNTFGSYECTCPIGYAL 2285
Query: 1299 RHCETF---VDVCPQ--MPCLNGGTCAVASNMPDGFICRCPPGFS--------------- 1338
R + +D C + C + G + N+ F+C CPPG +
Sbjct: 2286 REDQKMCKDLDECAEGLHDCESRG--MMCKNLIGTFMCICPPGMARRPDGEGCVDENECR 2343
Query: 1339 -------GARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHP 1391
RC + G +C E ++SG C C + + CQ S
Sbjct: 2344 TKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRN 2403
Query: 1392 QRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWD 1451
C + G +CEL P T + + DG + C
Sbjct: 2404 LVTKSECCCDGGRGW-GHQCELCPL-PGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCT 2461
Query: 1452 GGDCSLTMENPWANCS-------SPLPCWDYIN-----NQCDELCNTVECLFD-----NF 1494
G C TM + C S C D C+ +C E + +
Sbjct: 2462 NGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGY 2521
Query: 1495 ECQGNSKTCKYDKYCADHFKDNHCDQGC 1522
Q + KTCK C K ++C C
Sbjct: 2522 VLQEDGKTCKDLDEC--QTKQHNCQFLC 2547
Score = 471 bits (1211), Expect = e-132
Identities = 461/1611 (28%), Positives = 646/1611 (40%), Gaps = 387/1611 (24%)
Query: 115 CLNGGTCHMLSRDTYECTCQVGF---TGKECQWTDACLSHPCANGSTCTTVANQFSCKCL 171
CLNG +S +Y C C +G+ +C D C S+PC NG C + CKC
Sbjct: 505 CLNGRCIPTVS--SYRCECNMGYKQDANGDCIDVDECTSNPCTNGD-CVNTPGSYYCKCH 561
Query: 172 TGF----TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYCDSLYV 223
GF T Q C D++EC G G C+N GS+QC C GF G+ C
Sbjct: 562 AGFQRTPTKQAC-IDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDE 620
Query: 224 PCAPSPCVNGGTCRQTGDFTFECNCLPGF----EGSTCERNIDDCPNHRCQNGGVCVDGV 279
+ C+NG + G +F+C C PGF G C ++D+C G C++
Sbjct: 621 CTTTNMCLNGMCINEDG--SFKCICKPGFVLAPNGRYC-TDVDECQTPGICMNGHCINSE 677
Query: 280 NTYNCRCPP----QWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSG--- 332
++ C CPP G+ C + + C G + G VCV + G
Sbjct: 678 GSFRCDCPPGLAVGMDGRVCVD-----THMRSTCYGG----IKKG----VCVRPFPGAVT 724
Query: 333 --DDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DACISNP--CHKG 387
+ C N D C P A F +C G + D + C +P C G
Sbjct: 725 KSECCCANPDYGFGEPCQPCPA--KNSAEFHGLCSSGVGITVDGRDINECALDPDICANG 782
Query: 388 ALCDTNPLNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE 443
+C+ L G Y C C GY+ G +C D+DEC + N C++ G C NT G++ C
Sbjct: 783 -ICEN--LRGSYRCNCNSGYEPDASGRNCI-DIDEC-LVNRLLCDN-GLCRNTPGSYSCT 836
Query: 444 CLKGYA----GPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK------------ 487
C GY CE DINEC S+PC N A C + +G F C C PG K
Sbjct: 837 CPPGYVFRTETETCE-DINECESNPCVNGA-CRNNLGSFNCECSPGSKLSSTGLICIDSL 894
Query: 488 ---------GVHCELEIN------EC-------QSNPC---------------------- 503
CE+ IN EC +PC
Sbjct: 895 KGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCE 954
Query: 504 -VN----------NGQCVDKVNRFQCLCPPGF----TGPVC-QIDIDDC----SSTPCLN 543
VN NG+CV+ F C CP G TG VC I ++ C C++
Sbjct: 955 DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIH 1014
Query: 544 -------------------GAKCIDHP----NGYECQCATG---------FTGVLCEENI 571
G +C + P YE C G TG ++I
Sbjct: 1015 PVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDI 1074
Query: 572 DNCD--PDPCHHGQCQDGIDSYTCICNPGYMGAI----CSDQIDECYSSPCL-NDGRCID 624
+ C P C +G+C++ I S+ C CN G+ + C+D IDEC SP L G C++
Sbjct: 1075 NECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD-IDECRISPDLCGSGICVN 1133
Query: 625 LVNGYQCNCQPG-TSGV----NCEINFDDCASNP--CIHGICMDGINRYSCVCSPGF--- 674
++C C G SG NC ++ D+C NP C G C++ + C C G
Sbjct: 1134 TPGSFECECFEGYESGFMMMKNC-MDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELS 1192
Query: 675 -TGQRCNIDIDEC--ASNPCRKGATCINGVNGFRCICPEG----PHHPSCYSQVNEC-LS 726
+ + C +DI+EC + N CR G C+N + ++C C G P C + ++EC +
Sbjct: 1193 PSREDC-VDINECSLSDNLCRNG-KCVNMIGTYQCSCNPGYQATPDRQGC-TDIDECMIM 1249
Query: 727 NPCIHGNCTGGLSGYKCLCDAGWV----GINCEVDKNECLSNP-CQNGGTCDNLVNGYRC 781
N CT Y+C C G+ G +C D +EC +NP +GG C N+ YRC
Sbjct: 1250 NGGCDTQCTNSEGSYECSCSEGYALMPDGRSC-ADIDECENNPDICDGGQCTNIPGEYRC 1308
Query: 782 TCKKGFKG---YNCQVNIDEC--ASNPCLNQGTCFDDISGYTCHCVLPYTGK----NCQT 832
C GF ++++EC SN C+ G C + + CHC L Y+ K C
Sbjct: 1309 LCYDGFMASMDMKTCIDVNECDLNSNICM-FGECENTKGSFICHCQLGYSVKKGTTGCTD 1367
Query: 833 V-LAPCSPNPCENAAVCKESPNFESYTCLCAPGW--QGQRCTIDIDECI--SKPCMNHGL 887
V + C+ A C P S+ C C GW G +C ID+DEC + C +
Sbjct: 1368 VDECEIGAHNCDMHASCLNIPG--SFKCSCREGWIGNGIKC-IDLDECSNGTHQCSINAQ 1424
Query: 888 CHNTQGSYMCECPPGFS--GMDCEEDIDDCL--ANPCQNGGSCMDGVNTFSCLCLPGFT- 942
C NT GSY C C GF+ G C D+D+C N C+N G C++ + C C GFT
Sbjct: 1425 CVNTPGSYRCACSEGFTGDGFTC-SDVDECAENINLCEN-GQCLNVPGAYRCECEMGFTP 1482
Query: 943 ---GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD----GVHCENNINECTES- 994
CQ D++EC + GTC++ + C C G++ G +C +I+EC +
Sbjct: 1483 ASDSRSCQ-DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADPI 1540
Query: 995 SCFNGGTCVDGINSFSCLCPVGF----TGSFCL-HEINECSSHPCLNEGTCVDGLGTYRC 1049
+C N G CV+ + C CP F TG C+ + + C L G DG +
Sbjct: 1541 NCVN-GLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNC----YLKFGPRGDGSLSCNT 1595
Query: 1050 SCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ-KKAESQCLCPSGWAGAYCDVPNVSCDIA 1108
+G + +C + +PC+ TC E LCP G + + DI
Sbjct: 1596 EIGVGVSRSSCCCSLGKAWGNPCE---TCPPVNSTEYYTLCPGGEGFRPNPITIILEDID 1652
Query: 1109 ASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS----YCEEQLDECASNPCQHG-AT 1163
+ + LCQ G CIN + C+CP GY S CE+ +DEC ++P G T
Sbjct: 1653 ECQE---LPGLCQ-GGNCINTFGSFQCECPQGYYLSEDTRICED-IDECFAHPGVCGPGT 1707
Query: 1164 CSDFIGGYRCECVPGYQGVN------------------------------------CEYE 1187
C + +G Y C C P Y VN C Y
Sbjct: 1708 CYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYN 1767
Query: 1188 VDECQNQPCQ------------------------------------------NGGTCIDL 1205
V + N+PC+ G CI+
Sbjct: 1768 VGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQ 1827
Query: 1206 VNHFKCSCPPG---TRGLLCEENIDDCARGPH-CLNGGQCMDRIGGYSCRCLPGF--AGE 1259
+ F+C CP G LL E+ID+C+ G + C C++ G Y C C GF +
Sbjct: 1828 IGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPN 1887
Query: 1260 RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF---VDVCPQMPCLNG 1316
D NECL P L C+ L Y C+C + F +T VD C + PC N
Sbjct: 1888 GACVDRNECLEIPNVCSHGL-CVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGN- 1945
Query: 1317 GTCAVASNMPDGFICRCPPGFSGA---------RCQSSCGQVKCRKGEQCVHTASGPRCF 1367
GTC N + C C PGF C S GQV CR G +C + +C
Sbjct: 1946 GTC---KNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQV-CRNG-RCFNEIGSFKCL 2000
Query: 1368 C-------PSPRDC--ESGCASSPCQHGGSCHP---QRQPPYYSCQCAPPF 1406
C P ++C + C + P GSC P Q + C C P +
Sbjct: 2001 CNEGYELTPDGKNCIDTNECVALP----GSCSPGTCQNLEGSFRCICPPGY 2047
Score = 467 bits (1201), Expect = e-131
Identities = 472/1710 (27%), Positives = 668/1710 (39%), Gaps = 395/1710 (23%)
Query: 128 TYECTCQVGFT----GKECQWTDACLSHPCANGS-TCTTVANQFSCKCL----TGFTGQK 178
+++C C GF + C D C P GS C F C+C +GF K
Sbjct: 1095 SFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMK 1154
Query: 179 CETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYC-DSLYVPCAPSPCVNG 233
D++EC+ GGTC+N GS+QC CP G + + C D + + C NG
Sbjct: 1155 NCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNG 1214
Query: 234 GTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGV---CVDGVNTYNCRCPPQW 290
G T++C+C PG++ + + D NGG C + +Y C C +
Sbjct: 1215 KCVNMIG--TYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGY 1272
Query: 291 T----GQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSG----------DDCS 336
G+ C D+DEC P+ C +GG C N G Y C+C +G+ ++C
Sbjct: 1273 ALMPDGRSCA-DIDECENNPDIC-DGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECD 1330
Query: 337 ENIDDCAFASC--TPGS-----------------------------------TCIDRVAS 359
N + C F C T GS +C++ S
Sbjct: 1331 LNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGS 1390
Query: 360 FSCMCPEG--KAGLLCHLDDACI--SNPCHKGALCDTNPLNGQYICTCPQGYKGADCT-E 414
F C C EG G+ C D C ++ C A C P G Y C C +G+ G T
Sbjct: 1391 FKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTP--GSYRCACSEGFTGDGFTCS 1448
Query: 415 DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY---AGPRCEMDINECHSDPCQNDATC 471
DVDECA N N CE+ G+C+N GA+ CEC G+ + R DI+EC TC
Sbjct: 1449 DVDECA-ENINLCEN-GQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTC 1506
Query: 472 LDKIGGFTCLCMPGFK----GVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF--- 524
+ G F C+C G++ G +C +I+EC NG CV+ R++C CPP F
Sbjct: 1507 NNLPGMFHCICDDGYELDRTGGNC-TDIDECADPINCVNGLCVNTPGRYECNCPPDFQLN 1565
Query: 525 -TGPVC------------------------QIDIDDCSSTPCLNGAKCIDHP-------N 552
TG C +I + S+ C + K +P N
Sbjct: 1566 PTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVN 1625
Query: 553 GYE----CQCATGFTG---VLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM--- 600
E C GF + E+ID C P C G C + S+ C C GY
Sbjct: 1626 STEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSE 1685
Query: 601 -GAICSDQIDECYSSP-CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHG- 657
IC D IDEC++ P G C + + Y C C P VN N D + C
Sbjct: 1686 DTRICED-IDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSY 1744
Query: 658 ---ICMD----GINRYSCVCS-----------------------------PGF-----TG 676
C + + + C C+ PGF TG
Sbjct: 1745 NGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTG 1804
Query: 677 QRCNIDIDECASNP--CRKGATCINGVNGFRCICPEGPHHPSCY---SQVNECLS--NPC 729
+ +DIDEC P C G CIN + FRC CP G + ++EC + N C
Sbjct: 1805 KA--VDIDECKEIPGICANG-VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLC 1861
Query: 730 -IHGNCTGGLSGYKCLCDAGW--VGINCEVDKNECLS--NPCQNGGTCDNLVNGYRCTCK 784
+ +C Y+C C AG+ VD+NECL N C + G C +L Y+C C
Sbjct: 1862 QRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSH-GLCVDLQGSYQCICH 1920
Query: 785 KGFKGYNCQ---VNIDECASNPCLNQGTCFDDISGYTCHCV--LPYTGKNCQTVLAPCSP 839
GFK Q +++DEC +PC N GTC + + Y C C T N + CS
Sbjct: 1921 NGFKASQDQTMCMDVDECERHPCGN-GTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSS 1979
Query: 840 ---NPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECISKP-CMNHGLCHNT 891
C N E S+ CLC G++ G+ C ID +EC++ P + G C N
Sbjct: 1980 FFGQVCRNGRCFNE---IGSFKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQNL 2035
Query: 892 QGSYMCECPPGFSGM--------DCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF-- 941
+GS+ C CPPG+ +C+ED + CL GSC + F CLC PGF
Sbjct: 2036 EGSFRCICPPGYEVKSENCIDINECDEDPNICLF------GSCTNTPGGFQCLCPPGFVL 2089
Query: 942 --TGDKC-QTDMNECLSEPCKNGGTCS--DYVNSYTCKC--------------------- 975
G +C T + C + G CS N+ KC
Sbjct: 2090 SDNGRRCFDTRQSFCFTN--FENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDD 2147
Query: 976 QAGFDGV------------HCENNINECTESS--CFNGGTCVDGINSFSCLCPVG----F 1017
+ F + ++NEC ES C N G C++ SF C CP+G +
Sbjct: 2148 EVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSN-GQCINTDGSFRCECPMGYNLDY 2206
Query: 1018 TGSFCLHEINECS-SHPCLNEGTCVDGLGTYRCSCPLGYTG---KNCQTLVNLCSRSPCK 1073
TG C+ + +ECS +PC N GTC + +G++ C+C G+ NC+ +N C+++P
Sbjct: 2207 TGVRCV-DTDECSIGNPCGN-GTCTNVIGSFECNCNEGFEPGPMMNCED-INECAQNPLL 2263
Query: 1074 NKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSG-VCINAGNT 1132
C+ +C CP G+ A + + D+ G+ H C+ G +C N T
Sbjct: 2264 CAFRCMNTFGSYECTCPIGY--ALREDQKMCKDLDECAEGL---HDCESRGMMCKNLIGT 2318
Query: 1133 HYCQCPLGYT----GSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQGVNCEY 1186
C CP G G C ++ +EC + P C++G C + IG YRCEC G+Q +
Sbjct: 2319 FMCICPPGMARRPDGEGCVDE-NECRTKPGICENG-RCVNIIGSYRCECNEGFQSSSSGT 2376
Query: 1187 E---------VDECQNQPCQNGGTCIDLVNHFKCSCPPGTR-GLLCE------------- 1223
E E CQ + +LV +C C G G CE
Sbjct: 2377 ECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKI 2436
Query: 1224 -----------ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF----AGERCEGDINEC 1268
+ID+C P+ GQC++ +G + C C G+ +G C D++EC
Sbjct: 2437 CPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCI-DLDEC 2495
Query: 1269 LSNPCSSEGSLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMPCLNGGTCAVASN 1324
+P + C Y C C + G+ C+ +D C C N
Sbjct: 2496 SQSP--KPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKD-LDECQTKQHNCQFLCV---N 2549
Query: 1325 MPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQ 1384
GF C+CPPGF+ HTA C +C G S C
Sbjct: 2550 TLGGFTCKCPPGFTQH------------------HTA------CIDNNEC--GSQPSLCG 2583
Query: 1385 HGGSCHPQRQPPYYSCQCAPPFS----GSRCELYTAPPSTPPATCLSQYCADKARDGVCD 1440
G C Q P +SC+C FS G CE Q R G C
Sbjct: 2584 AKGIC--QNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCG-CP 2640
Query: 1441 EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLF-DNFECQGN 1499
+ H QW+ EN CS+P C + C + +C F
Sbjct: 2641 QGYIQH-YQWN----QCVDEN---ECSNPNACG---SASCYNTLGSYKCACPSGFSFDQF 2689
Query: 1500 SKTCKYDKYCADHFKDNHCDQGCNSEECGW 1529
S C C+ N C+ GC++ E G+
Sbjct: 2690 SSACHDVNECSS--SKNPCNYGCSNTEGGY 2717
Score = 452 bits (1162), Expect = e-126
Identities = 490/1790 (27%), Positives = 699/1790 (39%), Gaps = 474/1790 (26%)
Query: 34 PCVNEGMCVTYHNGTGYCKCPEGF----LGEYCQHRDPCEKNR--CQNGGTCVAQAMLGK 87
PC N G CV G+ YCKC GF + C D C +N C+NG CV G
Sbjct: 543 PCTN-GDCVNTP-GSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNG-RCVNTD--GS 597
Query: 88 ATCRCASGFT----GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT----G 139
C C +GF G++C C + CLNG + +++C C+ GF G
Sbjct: 598 FQCICNAGFELTTDGKNCV--DHDECTTTNMCLNGMCIN--EDGSFKCICKPGFVLAPNG 653
Query: 140 K------ECQWTDACLSHPCAN------------------GSTCTTVANQFSCK------ 169
+ ECQ C++ C N G C + +C
Sbjct: 654 RYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKG 713
Query: 170 -CLTGFTG--------------------QKCET---------------------DVNECD 187
C+ F G Q C D+NEC
Sbjct: 714 VCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECA 773
Query: 188 IPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
+ G C NL GSY+C C G+ +G+ C + + G CR T +
Sbjct: 774 LDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPG-S 832
Query: 244 FECNCLPGF----EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPP----QWTGQFC 295
+ C C PG+ E TCE +I++C ++ C N G C + + ++NC C P TG C
Sbjct: 833 YSCTCPPGYVFRTETETCE-DINECESNPCVN-GACRNNLGSFNCECSPGSKLSSTGLIC 890
Query: 296 TEDV-DECLL--QPNACQ---NGGT-----CANRNGGYGCVCVNGWSGDDC--------- 335
+ + C L Q + C+ NG T CA +G C C
Sbjct: 891 IDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKG 950
Query: 336 --SENIDDC-AFASCTPGSTCIDRVASFSCMCPEG----KAGLLC--------------- 373
E++++C F P C++ SF C CPEG G +C
Sbjct: 951 VTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDED 1010
Query: 374 ----------HLDDACISNPCHKGALCDTNPLNG--QYICTCPQG---------YKGADC 412
+D C + G C+ P G +Y CP+G G
Sbjct: 1011 ECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPF 1070
Query: 413 TEDVDEC----AMANSNPCEH------------------------------------AGK 432
+D++EC M C + +G
Sbjct: 1071 YKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGI 1130
Query: 433 CVNTDGAFHCECLKGYAG-----PRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPG 485
CVNT G+F CEC +GY C MDI+EC +P C+ TC++ G F C C G
Sbjct: 1131 CVNTPGSFECECFEGYESGFMMMKNC-MDIDECERNPLLCRG-GTCVNTEGSFQCDCPLG 1188
Query: 486 FK----GVHCELEINECQ-SNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQ---IDIDDCS 537
+ C ++INEC S+ NG+CV+ + +QC C PG+ + DID+C
Sbjct: 1189 HELSPSREDC-VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECM 1247
Query: 538 STPCLNG---AKCIDHPNGYECQCATGFT----GVLCEENIDNCD--PDPCHHGQCQDGI 588
+NG +C + YEC C+ G+ G C + ID C+ PD C GQC +
Sbjct: 1248 ---IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCAD-IDECENNPDICDGGQCTNIP 1303
Query: 589 DSYTCICNPGYMGAI----CSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGTS---GV 640
Y C+C G+M ++ C D ++EC +S G C + + C+CQ G S G
Sbjct: 1304 GEYRCLCYDGFMASMDMKTCID-VNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGT 1362
Query: 641 NCEINFDDC---ASNPCIHGICMDGINRYSCVCSPGFTGQ--RCNIDIDECA--SNPCRK 693
+ D+C A N +H C++ + C C G+ G +C ID+DEC+ ++ C
Sbjct: 1363 TGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC-IDLDECSNGTHQCSI 1421
Query: 694 GATCINGVNGFRCICPEG-PHHPSCYSQVNECLS--NPCIHGNCTGGLSGYKCLCDAGWV 750
A C+N +RC C EG S V+EC N C +G C Y+C C+ G+
Sbjct: 1422 NAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFT 1481
Query: 751 ----GINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASN 802
+C+ D +EC GTC+NL + C C G++ G NC +IDECA
Sbjct: 1482 PASDSRSCQ-DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADP 1539
Query: 803 PCLNQGTCFDDISGYTCHC----VLPYTG--------KNCQTVLAP-------------- 836
G C + Y C+C L TG NC P
Sbjct: 1540 INCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGV 1599
Query: 837 --------CS-----PNPCENAAVCKESPNFESYTCLCAPGWQGQR---CTI---DIDEC 877
CS NPCE C + E YT LC PG +G R TI DIDEC
Sbjct: 1600 GVSRSSCCCSLGKAWGNPCE---TCPPVNSTEYYT-LC-PGGEGFRPNPITIILEDIDEC 1654
Query: 878 ISKPCM-NHGLCHNTQGSYMCECPPGF---SGMDCEEDIDDCLANPCQNG-GSCMDGVNT 932
P + G C NT GS+ CECP G+ EDID+C A+P G G+C + +
Sbjct: 1655 QELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGN 1714
Query: 933 FSCLCLPGFT----GDKCQTDMNECLSEPCKNGGTCSD----YVNSYTCKC--------- 975
++C+C P + G C DM + NG TC + V C C
Sbjct: 1715 YTCICPPEYMQVNGGHNCM-DMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWN 1773
Query: 976 ----------QAGFDGVHCEN--------------NINECTE--SSCFNGGTCVDGINSF 1009
A F + C N +I+EC E C N G C++ I SF
Sbjct: 1774 KPCEPCPTPGTADFKTI-CGNIPGFTFDIHTGKAVDIDECKEIPGICAN-GVCINQIGSF 1831
Query: 1010 SCLCPVGFTGSFCL---HEINECSS--HPCLNEGTCVDGLGTYRCSCPLGY--------- 1055
C CP GF+ + L +I+ECS+ + C C++ G+YRC C G+
Sbjct: 1832 RCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACV 1891
Query: 1056 TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115
C + N+CS G CV + QC+C +G+ + + D+ R
Sbjct: 1892 DRNECLEIPNVCSH------GLCVDLQGSYQCICHNGFKAS--QDQTMCMDVDECER--- 1940
Query: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEE--QLDECAS---NPCQHGATCSDFIGG 1170
H C +G C N ++ C C G+ ++ + +DEC+S C++G C + IG
Sbjct: 1941 --HPC-GNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNG-RCFNEIGS 1996
Query: 1171 YRCECVPGYQ----GVNCEYEVDECQNQPCQ-NGGTCIDLVNHFKCSCPPGTRGLLCEEN 1225
++C C GY+ G NC + +EC P + GTC +L F+C CPPG + EN
Sbjct: 1997 FKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE--VKSEN 2053
Query: 1226 ---IDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA----GERC-EGDINECLSNPCSSEG 1277
I++C P+ G C + GG+ C C PGF G RC + + C +N + +
Sbjct: 2054 CIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKC 2113
Query: 1278 SLDCIQLTNDYLCVCR---SAFTGRHCE--------TFVDVCP----QMPCLNG------ 1316
S+ T C C G CE F D+CP +P L+
Sbjct: 2114 SVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVN 2173
Query: 1317 ------GTCAVAS--NMPDGFICRCPPG----FSGARC----QSSCGQVKCRKGEQCVHT 1360
G C+ N F C CP G ++G RC + S G C G C +
Sbjct: 2174 ECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGN-PCGNG-TCTNV 2231
Query: 1361 ASGPRCFC-----PSP-RDCE--SGCASSPCQHGGSCHPQRQPPYYSCQC 1402
C C P P +CE + CA +P C Y C C
Sbjct: 2232 IGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRC--MNTFGSYECTC 2279
Score = 448 bits (1153), Expect = e-125
Identities = 445/1518 (29%), Positives = 626/1518 (41%), Gaps = 323/1518 (21%)
Query: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
C+N G C H C+C +G++G YC P +N CQNGG C+ G C C
Sbjct: 153 CMNGGTCADDH-----CQCQKGYIGTYCGQ--PVCENGCQNGGRCI-----GPNRCACVY 200
Query: 95 GFTGEDCQ--YSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 152
GFTG C+ Y T PCF CQ TG C T C +
Sbjct: 201 GFTGPQCERDYRTG-PCFTQ---------------VNNQMCQGQLTGIVCTKTLCCATIG 244
Query: 153 CANGSTCTTVANQFSCKCLTGF-----TGQKCETDVNECD-IPGHCQHGGTCLNLPGSYQ 206
A G C Q C GF TG C+ DV+EC IPG CQ GG C+N GS++
Sbjct: 245 RAWGHPCEMCPAQPQ-PCRRGFIPNIRTGA-CQ-DVDECQAIPGICQ-GGNCINTVGSFE 300
Query: 207 CQCPQGF----TGQYCDSL-YVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNI 261
C+CP G T Q C+ + P C G G ++ C C G+ ST
Sbjct: 301 CRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVG--SYFCVCPRGYVTST----- 353
Query: 262 DDCPNHRC--QNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGT----C 315
RC Q G+C G+ N RC + G+ +C +P C GT C
Sbjct: 354 ---DGSRCIDQRTGMCFSGL--VNGRCAQELPGRMTKM---QCCCEPGRCWGIGTIPEAC 405
Query: 316 ANRNG-GYGCVCVNG-------WSGDDCSENIDDCAFA------SCTPGSTCIDRVASFS 361
R Y +C++G S FA PG T + +
Sbjct: 406 PVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGN 465
Query: 362 CMCP-EGKAG--------------LLCHLDDAC--ISNPCHKGALCDTNPLNGQYICTCP 404
P G AG +L D C +N C G P Y C C
Sbjct: 466 GFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCI---PTVSSYRCECN 522
Query: 405 QGYK---GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE---MDIN 458
GYK DC DVDEC SNPC + G CVNT G+++C+C G+ + +DI+
Sbjct: 523 MGYKQDANGDCI-DVDEC---TSNPCTN-GDCVNTPGSYYCKCHAGFQRTPTKQACIDID 577
Query: 459 ECHSDP--CQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQSNPCVNNGQCVDK 512
EC + C+N C++ G F C+C GF+ G +C ++ +EC + NG C+++
Sbjct: 578 ECIQNGVLCKN-GRCVNTDGSFQCICNAGFELTTDGKNC-VDHDECTTTNMCLNGMCINE 635
Query: 513 VNRFQCLCPPGF----TGPVCQIDIDDCSSTP--CLNGAKCIDHPNGYECQC----ATGF 562
F+C+C PGF G C D+D+C TP C+NG CI+ + C C A G
Sbjct: 636 DGSFKCICKPGFVLAPNGRYC-TDVDEC-QTPGICMNG-HCINSEGSFRCDCPPGLAVGM 692
Query: 563 TGVLCEENIDNCDPDPCHHGQCQDGI----------DSYTCICNPGY------------- 599
G +C +D C +G + G+ S C NP Y
Sbjct: 693 DGRVC---VDTHMRSTC-YGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKN 748
Query: 600 ---MGAICSD---------QIDECYSSP--CLNDGRCIDLVNGYQCNC----QPGTSGVN 641
+CS I+EC P C N G C +L Y+CNC +P SG N
Sbjct: 749 SAEFHGLCSSGVGITVDGRDINECALDPDICAN-GICENLRGSYRCNCNSGYEPDASGRN 807
Query: 642 CEINFDDCASNP--CIHGICMDGINRYSCVCSPGF---TGQRCNIDIDECASNPCRKGAT 696
C I+ D+C N C +G+C + YSC C PG+ T DI+EC SNPC GA
Sbjct: 808 C-IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGA- 865
Query: 697 CINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEV 756
C N + F C C G S + + G C + +C V IN
Sbjct: 866 CRNNLGSFNCECSPGSKLSS-----TGLICIDSLKGTCWLNIQDSRC-----EVNINGAT 915
Query: 757 DKNECLSN-PCQNGGTCDNLVNGYRC----TCKKG---FKGYNCQVNIDECASNP--CLN 806
K+EC + G C+ RC C +G KG C+ +++EC P C N
Sbjct: 916 LKSECCATLGAAWGSPCE------RCELDTACPRGLARIKGVTCE-DVNECEVFPGVCPN 968
Query: 807 QGTCFDDISGYTCHC----VLPYTGKNCQTV-LAPC----------SPNP---------C 842
G C + + C C L TG+ C + + C P P C
Sbjct: 969 -GRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCC 1027
Query: 843 ENAAV----CKE--SPNFESYTCLCAPG---------WQGQRCTIDIDECISKPCM-NHG 886
A C+E P + Y LC G G+ DI+EC + P M +G
Sbjct: 1028 AVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYG 1087
Query: 887 LCHNTQGSYMCECPPGFSGMDCEE----DIDDCLANPCQNG-GSCMDGVNTFSCLCLPGF 941
C NT GS+ C C GF+ +D EE DID+C +P G G C++ +F C C G+
Sbjct: 1088 KCRNTIGSFKCRCNSGFA-LDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGY 1146
Query: 942 TGD----KCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGFDGVHCEN---NINEC- 991
K D++EC P C+ GGTC + S+ C C G + +INEC
Sbjct: 1147 ESGFMMMKNCMDIDECERNPLLCR-GGTCVNTEGSFQCDCPLGHELSPSREDCVDINECS 1205
Query: 992 -TESSCFNGGTCVDGINSFSCLCPVGFTGS----FCLHEINECSSHPCLNEGTCVDGLGT 1046
+++ C N G CV+ I ++ C C G+ + C +I+EC + C + G+
Sbjct: 1206 LSDNLCRN-GKCVNMIGTYQCSCNPGYQATPDRQGCT-DIDECMIMNGGCDTQCTNSEGS 1263
Query: 1047 YRCSCPLGYT----GKNCQTLVNLCSRSP-CKNKGTCVQKKAESQCLCPSGWAGAY---- 1097
Y CSC GY G++C ++ C +P + G C E +CLC G+ +
Sbjct: 1264 YECSCSEGYALMPDGRSCAD-IDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKT 1322
Query: 1098 CDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT---GSYCEEQLDEC- 1153
C N CD L ++C G C N + C C LGY+ G+ +DEC
Sbjct: 1323 CIDVN-ECD--------LNSNICMF-GECENTKGSFICHCQLGYSVKKGTTGCTDVDECE 1372
Query: 1154 -ASNPCQHGATCSDFIGGYRCECVPGY--QGVNCEYEVDECQN--QPCQNGGTCIDLVNH 1208
++ C A+C + G ++C C G+ G+ C ++DEC N C C++
Sbjct: 1373 IGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC-IDLDECSNGTHQCSINAQCVNTPGS 1431
Query: 1209 FKCSCPPGTR--GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF---AGERCEG 1263
++C+C G G C + +D+CA + GQC++ G Y C C GF + R
Sbjct: 1432 YRCACSEGFTGDGFTCSD-VDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ 1490
Query: 1264 DINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF----TGRHCETFVDVCPQMPCLNGGTC 1319
DI+EC G+ C L + C+C + TG +C + + C+NG
Sbjct: 1491 DIDECSFQNICVFGT--CNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNG--- 1545
Query: 1320 AVASNMPDGFICRCPPGF 1337
+ N P + C CPP F
Sbjct: 1546 -LCVNTPGRYECNCPPDF 1562
Score = 391 bits (1005), Expect = e-108
Identities = 421/1548 (27%), Positives = 607/1548 (39%), Gaps = 350/1548 (22%)
Query: 201 LPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC-ER 259
LPG QC VP + C +G R C C G STC +
Sbjct: 104 LPGGNQC--------------IVPICRNSCGDGFCSRPN-----MCTCSSGQISSTCGSK 144
Query: 260 NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRN 319
+I C + RC NGG C D +C+C + G +C + V E N CQNGG C N
Sbjct: 145 SIQQC-SVRCMNGGTCADD----HCQCQKGYIGTYCGQPVCE-----NGCQNGGRCIGPN 194
Query: 320 GGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDAC 379
C CV G++G C + C +V + MC G++C C
Sbjct: 195 R---CACVYGFTGPQCERDYRT---------GPCFTQVNNQ--MCQGQLTGIVCTKTLCC 240
Query: 380 ISNPCHKGALCDTNPLNGQYICTCPQGY----KGADCTEDVDECAMANSNPCEHAGKCVN 435
+ G C+ P Q C +G+ + C +DVDEC A C+ G C+N
Sbjct: 241 ATIGRAWGHPCEMCPAQPQ---PCRRGFIPNIRTGAC-QDVDEC-QAIPGICQ-GGNCIN 294
Query: 436 TDGAFHCECLKGY----AGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGF--- 486
T G+F C C G+ +CE DI+EC P C+ C + +G + C+C G+
Sbjct: 295 TVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGICET-GECSNTVGSYFCVCPRGYVTS 352
Query: 487 -KGVHC-ELEINECQSNPCVNNGQCVD----KVNRFQCLCPPGFTGPV------CQIDID 534
G C + C S + NG+C ++ + QC C PG + C +
Sbjct: 353 TDGSRCIDQRTGMCFSG--LVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGS 410
Query: 535 DCSSTPCLNGAKCIDHPNGYECQCA-TGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTC 593
+ C++G P + TG G N + P G
Sbjct: 411 EEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGF--- 467
Query: 594 ICNPGYMGA---------------ICSDQIDEC--YSSPCLNDGRCIDLVNGYQCNCQPG 636
+PG GA I + ID C +++ CLN GRCI V+ Y+C C G
Sbjct: 468 --SPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLN-GRCIPTVSSYRCECNMG 524
Query: 637 ---TSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGF----TGQRCNIDIDECASN 689
+ +C I+ D+C SNPC +G C++ Y C C GF T Q C IDIDEC N
Sbjct: 525 YKQDANGDC-IDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQAC-IDIDECIQN 582
Query: 690 P--CRKGATCINGVNGFRCICPEG----PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC 743
C+ G C+N F+CIC G +C +N C++G C +KC
Sbjct: 583 GVLCKNGR-CVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKC 641
Query: 744 LCDAGWV----GINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK-GYNCQVNIDE 798
+C G+V G C D +EC + G C N +RC C G G + +V +D
Sbjct: 642 ICKPGFVLAPNGRYC-TDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDT 700
Query: 799 CASNPC---LNQGTCFDDISGYT----CHCVLPYTGKNCQTVLAPCSPNPCENAAV---- 847
+ C + +G C G C C P G PC P P +N+A
Sbjct: 701 HMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFG-----EPCQPCPAKNSAEFHGL 755
Query: 848 ----------------CKESPNF----------ESYTCLCAPGWQ----GQRCTIDIDEC 877
C P+ SY C C G++ G+ C IDIDEC
Sbjct: 756 CSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC-IDIDEC 814
Query: 878 -ISKPCMNHGLCHNTQGSYMCECPPGF---SGMDCEEDIDDCLANPCQNGGSCMDGVNTF 933
+++ ++GLC NT GSY C CPPG+ + + EDI++C +NPC N G+C + + +F
Sbjct: 815 LVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVN-GACRNNLGSF 873
Query: 934 SCLCLPG----FTG--------DKCQTDMNECLSEPCKNGGT-----CSDYVNSYTCKCQ 976
+C C PG TG C ++ + E NG T C+ ++ C+
Sbjct: 874 NCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCE 933
Query: 977 ------------AGFDGVHCENNINECT--ESSCFNGGTCVDGINSFSCLCPVGF----T 1018
A GV CE ++NEC C N G CV+ SF C CP G T
Sbjct: 934 RCELDTACPRGLARIKGVTCE-DVNECEVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGT 991
Query: 1019 GSFCLH----------EINECSSHP----------CLNEGT-----CVD----GLGTYRC 1049
G CL + +EC HP C G C + G Y
Sbjct: 992 GRVCLDIRMEQCYLKWDEDEC-IHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYET 1050
Query: 1050 SCPLG---------YTGKNCQTLVNLCSRSP-CKNKGTCVQKKAESQCLCPSGWAGAYCD 1099
CP G TG+ +N C P G C +C C SG+A D
Sbjct: 1051 LCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFA---LD 1107
Query: 1100 VPNVSC-DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSY-----CEEQLDEC 1153
+ +C DI R + LC SG+C+N + C+C GY + C + +DEC
Sbjct: 1108 MEERNCTDIDECR---ISPDLC-GSGICVNTPGSFECECFEGYESGFMMMKNCMD-IDEC 1162
Query: 1154 ASNPCQ-HGATCSDFIGGYRCECVPGYQ----GVNCEYEVDEC--QNQPCQNGGTCIDLV 1206
NP G TC + G ++C+C G++ +C +++EC + C+N G C++++
Sbjct: 1163 ERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDC-VDINECSLSDNLCRN-GKCVNMI 1220
Query: 1207 NHFKCSCPPGTRGLLCEE---NIDDCARGPHCLNGG---QCMDRIGGYSCRCLPGFA--- 1257
++CSC PG + + +ID+C +NGG QC + G Y C C G+A
Sbjct: 1221 GTYQCSCNPGYQATPDRQGCTDIDECM----IMNGGCDTQCTNSEGSYECSCSEGYALMP 1276
Query: 1258 -GERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF-TGRHCETFVDV--CPQMPC 1313
G C DI+EC +NP +G C + +Y C+C F +T +DV C
Sbjct: 1277 DGRSC-ADIDECENNPDICDGG-QCTNIPGEYRCLCYDGFMASMDMKTCIDVNECD---- 1330
Query: 1314 LNGGTC--AVASNMPDGFICRCPPGFSGARCQSSC--------GQVKCRKGEQCVHTASG 1363
LN C N FIC C G+S + + C G C C++
Sbjct: 1331 LNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGS 1390
Query: 1364 PRCFCPSP-----------RDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412
+C C +C +G + C C P Y C C+ F+G
Sbjct: 1391 FKCSCREGWIGNGIKCIDLDECSNG--THQCSINAQC--VNTPGSYRCACSEGFTGD--- 1443
Query: 1413 LYTAPPSTPPATCLS-QYCADK---ARDGVCDEACNSHACQWDGGDCSLTMENPWANCSS 1468
TC CA+ +G C ++ C+ + G T + +C
Sbjct: 1444 ---------GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMG---FTPASDSRSCQD 1491
Query: 1469 PLPCWDYINNQCDELCNTVECLF-----DNFECQGNSKTCKYDKYCAD 1511
C + N CN + +F D +E C CAD
Sbjct: 1492 IDEC-SFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECAD 1538
Score = 378 bits (970), Expect = e-104
Identities = 462/1853 (24%), Positives = 690/1853 (37%), Gaps = 456/1853 (24%)
Query: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCE--KNRCQN 75
C PA CR G+ P + G CQ D C+ CQ
Sbjct: 251 CEMCPAQPQPCRRGFIPNIRTGA---------------------CQDVDECQAIPGICQ- 288
Query: 76 GGTCVAQAMLGKATCRCASGF----TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYEC 131
GG C+ +G CRC +G T + C+ C + G C + +Y C
Sbjct: 289 GGNCI--NTVGSFECRCPAGHKQSETTQKCE--DIDECSIIPGICETGECSN-TVGSYFC 343
Query: 132 TCQVGFT----GKEC--QWTDACLSHPCANGSTCTTVANQFS---CKCLTGFTGQKC--- 179
C G+ G C Q T C S NG + + + C C G +C
Sbjct: 344 VCPRGYVTSTDGSRCIDQRTGMCFS-GLVNGRCAQELPGRMTKMQCCCEPG----RCWGI 398
Query: 180 ETDVNECDIPGHCQHGGTCLN------LPGSYQCQ---------CPQGFTGQY--CDSLY 222
T C + G ++ C++ +PGS + P G Y + +
Sbjct: 399 GTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGF 458
Query: 223 VPC------------------APSPCVNGGT--------CRQTGDFTFECNCLPGFEGST 256
+P P + G T C+ + C+P
Sbjct: 459 IPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYR 518
Query: 257 CERN-------------IDDCPNHRCQNGGVCVDGVNTYNCRCPPQW----TGQFCTEDV 299
CE N +D+C ++ C NG CV+ +Y C+C + T Q C D+
Sbjct: 519 CECNMGYKQDANGDCIDVDECTSNPCTNGD-CVNTPGSYYCKCHAGFQRTPTKQACI-DI 576
Query: 300 DECLLQPNACQNGGTCANRNGGYGCVCVNGW----SGDDCSENIDDCAFASCTPGSTCID 355
DEC+ C+N G C N +G + C+C G+ G +C ++ D+C + CI+
Sbjct: 577 DECIQNGVLCKN-GRCVNTDGSFQCICNAGFELTTDGKNCVDH-DECTTTNMCLNGMCIN 634
Query: 356 RVASFSCMC-------PEGKAGL---LCHLDDACISNPC--HKGAL-CDTNP-----LNG 397
SF C+C P G+ C C++ C +G+ CD P ++G
Sbjct: 635 EDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDG 694
Query: 398 QYIC-------TCPQGYKGADCTEDV------DECAMAN-----SNPCEHAGKCVNTDGA 439
+ +C TC G K C EC AN PC+
Sbjct: 695 R-VCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCP--AKNSAE 751
Query: 440 FHCECLKGYAGPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGFK----GVHCEL 493
FH C G DINEC DP C N C + G + C C G++ G +C +
Sbjct: 752 FHGLCSSGVGITVDGRDINECALDPDICAN-GICENLRGSYRCNCNSGYEPDASGRNC-I 809
Query: 494 EINECQSNPCV-NNGQCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTPCLNGAKCI 548
+I+EC N + +NG C + + C CPPG+ C+ DI++C S PC+NGA C
Sbjct: 810 DIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCE-DINECESNPCVNGA-CR 867
Query: 549 DHPNGYECQCATG----FTGVLCEENIDNCDPDPCHHGQCQDGIDSYT----CICNPG-- 598
++ + C+C+ G TG++C +++ +C+ I+ T C G
Sbjct: 868 NNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAA 927
Query: 599 --------------------YMGAICSDQIDECYSSP--CLNDGRCIDLVNGYQCNCQ-- 634
G C D ++EC P C N GRC++ + C C
Sbjct: 928 WGSPCERCELDTACPRGLARIKGVTCED-VNECEVFPGVCPN-GRCVNSKGSFHCECPEG 985
Query: 635 ---PGTSGVNCEINFDDC----ASNPCIHGICMDGINRYSCVCSPGFT-GQRCNIDIDEC 686
GT V +I + C + CIH + +C C+ G G C +EC
Sbjct: 986 LTLDGTGRVCLDIRMEQCYLKWDEDECIHPV-PGKFRMDACCCAVGAAWGTEC----EEC 1040
Query: 687 ASNPCRKGATCINGVNGFRCICPEGPHHPS---------CYSQVNECLSNP--CIHGNCT 735
G + +CP G + Y +NEC + P C +G C
Sbjct: 1041 PK----------PGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCR 1090
Query: 736 GGLSGYKCLCDAGWV----GINCEVDKNECLSNPCQNG-GTCDNLVNGYRCTCKKGFKG- 789
+ +KC C++G+ NC D +EC +P G G C N + C C +G++
Sbjct: 1091 NTIGSFKCRCNSGFALDMEERNC-TDIDECRISPDLCGSGICVNTPGSFECECFEGYESG 1149
Query: 790 ----YNCQVNIDECASNPCL-NQGTCFDDISGYTCHCVLPY----TGKNCQTV-LAPCSP 839
NC ++IDEC NP L GTC + + C C L + + ++C + S
Sbjct: 1150 FMMMKNC-MDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSD 1208
Query: 840 NPCENAAVCKESPNFESYTCLCAPGWQG----QRCTIDIDECISKPCMNHGL---CHNTQ 892
N C N K +Y C C PG+Q Q CT DIDEC+ MN G C N++
Sbjct: 1209 NLCRNG---KCVNMIGTYQCSCNPGYQATPDRQGCT-DIDECM---IMNGGCDTQCTNSE 1261
Query: 893 GSYMCECPPGFS----GMDCEEDIDDCLANP-CQNGGSCMDGVNTFSCLCLPGFTGD--- 944
GSY C C G++ G C DID+C NP +GG C + + CLC GF
Sbjct: 1262 GSYECSCSEGYALMPDGRSC-ADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDM 1320
Query: 945 KCQTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAGFD---GVHCENNINECT--ESSCFN 998
K D+NEC L+ G C + S+ C CQ G+ G +++EC +C
Sbjct: 1321 KTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDM 1380
Query: 999 GGTCVDGINSFSCLCPVGFTGS--FCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPLG 1054
+C++ SF C C G+ G+ C+ +++ECS +H C CV+ G+YRC+C G
Sbjct: 1381 HASCLNIPGSFKCSCREGWIGNGIKCI-DLDECSNGTHQCSINAQCVNTPGSYRCACSEG 1439
Query: 1055 YTG--------KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCD 1106
+TG C +NLC G C+ +C C G+ A D
Sbjct: 1440 FTGDGFTCSDVDECAENINLC------ENGQCLNVPGAYRCECEMGFTPASDSRSCQDID 1493
Query: 1107 IAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY----TGSYCEEQLDECASNPCQHGA 1162
+ +++C G C N +C C GY TG C + +DECA
Sbjct: 1494 ECS------FQNICVF-GTCNNLPGMFHCICDDGYELDRTGGNCTD-IDECADPINCVNG 1545
Query: 1163 TCSDFIGGYRCECVPGYQ----GVNC-EYEVDECQNQPCQNGGTCIDL-------VNHFK 1210
C + G Y C C P +Q GV C + V C + G + V+
Sbjct: 1546 LCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSS 1605
Query: 1211 CSCP------------------------PGTRGL------LCEENIDDCARGPHCLNGGQ 1240
C C PG G + E+ID+C P GG
Sbjct: 1606 CCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGN 1665
Query: 1241 CMDRIGGYSCRCLPGF---AGERCEGDINECLSNP--------CSSEGSLDCI------Q 1283
C++ G + C C G+ R DI+EC ++P ++ G+ CI Q
Sbjct: 1666 CINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQ 1725
Query: 1284 LTNDYLCV------CRSAFTGRHCETFV--DVCPQMPC--LNGG--------TCAVASNM 1325
+ + C+ C ++ G CE + +V +M C N G C
Sbjct: 1726 VNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTA 1785
Query: 1326 PDGFICRCPPGFS------GARCQSSCGQVK--CRKGEQCVHTASGPRCFCPSP------ 1371
IC PGF+ A C ++ C G C++ RC CP+
Sbjct: 1786 DFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANG-VCINQIGSFRCECPTGFSYNDL 1844
Query: 1372 -------RDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPAT 1424
+C +G + CQ C P Y C+CA F S P
Sbjct: 1845 LLVCEDIDECSNG--DNLCQRNADC--INSPGSYRCECAAGFKLS-----------PNGA 1889
Query: 1425 CLSQ----YCADKARDGVCDEACNSHACQWDGG-----DCSLTMENPWANCSSPLPCWDY 1475
C+ + + G+C + S+ C G D ++ M+ + PC
Sbjct: 1890 CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMD---VDECERHPCG-- 1944
Query: 1476 INNQCDELCNTVECL-FDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEEC 1527
N C + CL + FE N+ D+ C+ F Q C + C
Sbjct: 1945 -NGTCKNTVGSYNCLCYPGFELTHNNDCLDIDE-CSSFF-----GQVCRNGRC 1990
Score = 325 bits (832), Expect = 4e-88
Identities = 376/1442 (26%), Positives = 554/1442 (38%), Gaps = 354/1442 (24%)
Query: 305 QPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMC 364
Q + + C +R Y C GW + G+ CI + SC
Sbjct: 79 QQDVLRGPNVCGSRFHSY---CCPGWK--------------TLPGGNQCIVPICRNSCGD 121
Query: 365 PEGKAGLLCHLDDACISNPCHKGAL--CDTNPLNGQYI----CTCPQGYKGADCTEDVDE 418
+C IS+ C ++ C +NG C C +GY G C + V E
Sbjct: 122 GFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCE 181
Query: 419 CAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPC---QNDATCLDKI 475
N C++ G+C+ G C C+ G+ GP+CE D + PC N+ C ++
Sbjct: 182 ------NGCQNGGRCI---GPNRCACVYGFTGPQCERDY---RTGPCFTQVNNQMCQGQL 229
Query: 476 GGFTC---LC--------------------------MPGFKGVHCELEINECQSNPCV-N 505
G C LC +P + C+ +++ECQ+ P +
Sbjct: 230 TGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQ-DVDECQAIPGICQ 288
Query: 506 NGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATG 561
G C++ V F+C CP G T C+ DID+CS P + C TG
Sbjct: 289 GGNCINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGI---------------CETG 332
Query: 562 FTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM----GAICSDQ-IDECYSSPC 616
+C + + SY C+C GY+ G+ C DQ C+S
Sbjct: 333 ---------------------ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSG-- 369
Query: 617 LNDGRCIDLVNG----YQCNCQP------GTSGVNCEINFDDCASNPCIHGICMDGINRY 666
L +GRC + G QC C+P GT C + + C+ G+ M GI
Sbjct: 370 LVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPG- 428
Query: 667 SCVCSPGFTGQRCNIDI-DECASNPCRKGATCINGVNGFR-----CICPEGPHHP--SCY 718
S PG TG + P G I G NGF G P +
Sbjct: 429 SAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGL 488
Query: 719 SQVNECL------SNPCIHGNCTGGLSGYKCLCDAGW---VGINCEVDKNECLSNPCQNG 769
+ +N+ + +N C++G C +S Y+C C+ G+ +C +D +EC SNPC N
Sbjct: 489 TILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDC-IDVDECTSNPCTN- 546
Query: 770 GTCDNLVNGYRCTCKKGFKGYNCQ---VNIDECASNPCL-NQGTCFDDISGYTCHC---- 821
G C N Y C C GF+ + ++IDEC N L G C + + C C
Sbjct: 547 GDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGF 606
Query: 822 VLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGW----QGQRCTIDIDEC 877
L GKNC + N C N E +F+ C+C PG+ G+ CT D+DEC
Sbjct: 607 ELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFK---CICKPGFVLAPNGRYCT-DVDEC 662
Query: 878 ISKPCMNHGLCHNTQGSYMCECPPGFS-GMDCEEDIDDCLANPCQNG---GSCM----DG 929
+ +G C N++GS+ C+CPPG + GMD +D + + C G G C+
Sbjct: 663 QTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGA 722
Query: 930 VNTFSCLCLP---GFTGDKCQ------------------------TDMNECLSEP--CKN 960
V C C GF G+ CQ D+NEC +P C N
Sbjct: 723 VTKSECCCANPDYGF-GEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICAN 781
Query: 961 GGTCSDYVNSYTCKCQAGFD----GVHCENNINECTESSCF-NGGTCVDGINSFSCLCPV 1015
G C + SY C C +G++ G +C +I+EC + + G C + S+SC CP
Sbjct: 782 -GICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGLCRNTPGSYSCTCPP 839
Query: 1016 GF---TGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSC----PLGYTGKNC-QTLVNLC 1067
G+ T + +INEC S+PC+N G C + LG++ C C L TG C +L C
Sbjct: 840 GYVFRTETETCEDINECESNPCVN-GACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTC 898
Query: 1068 ----SRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR-----RGVLVEH 1118
S C+ K+E + W G+ C+ D A R +GV E
Sbjct: 899 WLNIQDSRCEVNINGATLKSECCATLGAAW-GSPCE--RCELDTACPRGLARIKGVTCED 955
Query: 1119 L--CQ------HSGVCINAGNTHYCQCPLGY----TGSYC-EEQLDEC----ASNPCQHG 1161
+ C+ +G C+N+ + +C+CP G TG C + ++++C + C H
Sbjct: 956 VNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHP 1015
Query: 1162 ATCSDFIGGYR---CECVPGYQ-GVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGT 1217
G +R C C G G CE C GT ++ CP G
Sbjct: 1016 VP-----GKFRMDACCCAVGAAWGTECE---------ECPKPGT-----KEYETLCPRGA 1056
Query: 1218 ---------RGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA---GERCEGDI 1265
G ++I++C P G+C + IG + CRC GFA ER DI
Sbjct: 1057 GFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDI 1116
Query: 1266 NECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG-----RHCETFVDVCPQMPCL-NGGTC 1319
+EC +P GS C+ + C C + ++C +D C + P L GGTC
Sbjct: 1117 DECRISP-DLCGSGICVNTPGSFECECFEGYESGFMMMKNCMD-IDECERNPLLCRGGTC 1174
Query: 1320 AVASNMPDGFICRCPPGFSGARCQSSCGQVK--------CRKGEQCVHTASGPRCFCPSP 1371
N F C CP G + + C + CR G +CV+ +C
Sbjct: 1175 V---NTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNMIGTYQC----- 1225
Query: 1372 RDCESGCASSPCQHG-----------GSCHPQ--RQPPYYSCQCAPPFS----GSRCELY 1414
C G ++P + G G C Q Y C C+ ++ G C
Sbjct: 1226 -SCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADI 1284
Query: 1415 TAPPSTPPATCLSQYCADKARDGVCDEACNSHACQ-WDGGDCSLTMENPWANCSSPLPCW 1473
+ P D G C + C +DG S+ M+ C
Sbjct: 1285 DECENNP----------DICDGGQCTNIPGEYRCLCYDGFMASMDMKT----------CI 1324
Query: 1474 DYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNS-EECGWDGL 1532
D N+CD N+ C+F E S C +C + GC +EC
Sbjct: 1325 DV--NECD--LNSNICMFGECENTKGSFIC----HCQLGYSVKKGTTGCTDVDECEIGAH 1376
Query: 1533 DC 1534
+C
Sbjct: 1377 NC 1378
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 498 bits (1282), Expect = e-140
Identities = 470/1640 (28%), Positives = 663/1640 (40%), Gaps = 351/1640 (21%)
Query: 33 EPCVNEGMCVTYHNGTGYCKCPEGF----LGEYCQHRDPCEKNR--CQNGGTCVAQAMLG 86
+P + G T +G+ C+CP G G C+ D C + C +G CV ++G
Sbjct: 1078 DPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHG-QCVN--VIG 1134
Query: 87 KATCRCASGFTGEDCQYSTSHPCFVSRPCL--NGGT-CHMLSRD-TYECTCQVGFT---- 138
C C +GF + C C NGG H ++ + +Y C+C G++
Sbjct: 1135 AFQCSCHAGFQSTPDRQG----CVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD 1190
Query: 139 GKECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTG---QKCETDVNECDIPGHCQ 193
G+ C D C +P C G CT + C C GF + DV+ECD+ H
Sbjct: 1191 GRACADVDECEENPRVCDQGH-CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHIC 1249
Query: 194 HGGTCLNLPGSYQCQCPQGFT-----------------GQYCDSLYVPCAPSPCVNGGTC 236
G C N GS+ C C G+ G CDS + C P
Sbjct: 1250 LHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDS-HASCLNIPG------ 1302
Query: 237 RQTGDFTFECNCLPGFEGSTCE-RNIDDCPN--HRCQNGGVCVDGVNTYNCRCPPQWTGQ 293
+F C CLPG+ G E ++D+C + HRC G C++ +Y C C + G
Sbjct: 1303 ------SFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGD 1356
Query: 294 -FCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSG----------DDCSENIDDC 342
F ED DEC + C NG C N GGY C C G+ D+C++ + C
Sbjct: 1357 GFFCEDRDECAENVDLCDNG-QCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG-NLC 1414
Query: 343 AFASCT--PG---------------------------------STCIDRVASFSCMCPE- 366
AF SC PG CI+ S+ C CP+
Sbjct: 1415 AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQD 1474
Query: 367 -------------------------GKAGLLCHLD--------DACIS------NPCHKG 387
G +G+ C + C S NPC
Sbjct: 1475 FELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELC 1534
Query: 388 ALCDTNPLNGQYICTCP--QGYKGADCT---EDVDECAMANSNPCEHAGKCVNTDGAFHC 442
+ +T +Y CP +G++ T ED+DEC C+ G CVNT G+F C
Sbjct: 1535 PMANTT----EYRTLCPGGEGFQPNRITVILEDIDECQEL-PGLCQ-GGDCVNTFGSFQC 1588
Query: 443 ECLKGYAGPR----CEMDINEC--HSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEIN 496
EC GY CE DI+EC HS C TC + +G +TC+C + V+
Sbjct: 1589 ECPPGYHLSEHTRICE-DIDECSTHSGIC-GPGTCYNTLGNYTCVCPAEYLQVNGGNNCM 1646
Query: 497 ECQSNPCVN--NGQCVDKV--NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPN 552
+ + + C NG C +++ N + +C C +I + PC I
Sbjct: 1647 DMRKSVCFRHYNGTCQNELAFNVTRKMC-------CCSYNIGQAWNRPCEACPTPISPD- 1698
Query: 553 GYECQCATGFTGVLCEEN------IDNCDPDP--CHHGQCQDGIDSYTCICNPGYMG--- 601
Y+ C G L + + ID C P C +G C + I S+ C C G+
Sbjct: 1699 -YQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSI 1757
Query: 602 AICSDQIDECYS--SPCLNDGRCIDLVNGYQCNCQPG---TSGVNCEINFDDCASNP--C 654
+ + +DEC S SPC + CI++ Y+C C G + G C + ++C P C
Sbjct: 1758 LLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGAC-VGRNECREIPNVC 1816
Query: 655 IHGICMDGINRYSCVCSPGFTG---QRCNIDIDECASNPCRKGATCINGVNGFRCICPEG 711
HG CMD Y C+C GF Q +DIDEC PC G TC N + + C+C G
Sbjct: 1817 SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNG-TCKNIIGSYNCLCFPG 1875
Query: 712 ---PHHPSC--YSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWV----GINCEVDKNECL 762
H+ C + + + C G+C + CLC G+ G NC VD NECL
Sbjct: 1876 FVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECL 1934
Query: 763 S--NPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ-VNIDECASNP--CLNQGTCFDDISGY 817
S C G TC NL +RC C GF+ + ++IDEC+ P CL GTC + +
Sbjct: 1935 SLAGTCLPG-TCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLF-GTCTNSPGSF 1992
Query: 818 TCHC----VLPYTGKNC-QTVLAPCSPNPCENAAVCKESPNFESYTCLCAP----GWQGQ 868
C C VL G C T + C ++ N C C+ GW G
Sbjct: 1993 QCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGW-GD 2051
Query: 869 RCTI----------------------------DIDECISKP--CMNHGLCHNTQGSYMCE 898
C + D++EC P C N G+C NT GS+ CE
Sbjct: 2052 PCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTN-GVCVNTDGSFRCE 2110
Query: 899 CPPGFS----GMDCEEDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT--DMN 951
CP G+S G++C D D+C + +PC G +C + + F C C GF T D++
Sbjct: 2111 CPFGYSLDFTGINCV-DTDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMTCEDID 2168
Query: 952 ECLSEPCKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINECTESS--CF-NGGTCVD 1004
EC P C + SY C C AG+ DG C + ++EC + C G C +
Sbjct: 2169 ECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD-VDECADGQQDCHARGMECKN 2227
Query: 1005 GINSFSCLCPVGF-----TGSFCLHEINECSSHP--CLNEGTCVDGLGTYRCSCPLGYTG 1057
I +F+C+CP G +G C + NEC + P C+N G CV+ G++RC C G+
Sbjct: 2228 LIGTFACVCPPGMRPLPGSGEGCTDD-NECHAQPDLCVN-GRCVNTAGSFRCDCDEGFQP 2285
Query: 1058 KNCQTLVNLCSRSPC---------KNKGTCVQKKAESQCLCPSG--WAGA--YCDVPNVS 1104
T + + PC ++ + + ++C C G W C +P S
Sbjct: 2286 SPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTS 2345
Query: 1105 C---------DIAASRRGV----LVEHLCQHSGVCINAGNTHYCQCPLGYT----GSYCE 1147
A R V ++ HLC H G CIN+ + C C GYT + C
Sbjct: 2346 AYRKLCPHGSGYTAEGRDVDECRMLAHLCAH-GECINSLGSFRCHCQAGYTPDATATTCL 2404
Query: 1148 EQLDECASNPCQHGATCSDFIGGYRCECVPGY----QGVNCEYEVDECQNQPCQNGGTCI 1203
+ +DEC+ P C + G + C C GY G C+ ++DEC ++ C+
Sbjct: 2405 D-MDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCV 2462
Query: 1204 DLVNHFKCSCPPG--TRGLLCEENIDDCARGPH-CLNGGQCMDRIGGYSCRCLPGF---- 1256
+ V F C CPPG C +N D+C+ P C G C + G + C C GF
Sbjct: 2463 NTVGAFTCRCPPGFTQHHQACFDN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 1257 AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNG 1316
+G CE D+NEC G C Y C C FT +H + V L+
Sbjct: 2522 SGHGCE-DVNECDGPHRCQHG---CQNQLGGYRCSCPQGFT-QHSQWAQCVDENECALSP 2576
Query: 1317 GTCAVAS--NMPDGFICRCPPGFSGARCQSSCGQV-KC--RKGE---QCVHTASGPRCFC 1368
TC AS N GF C CP GF + C +V +C R+G C +T G C C
Sbjct: 2577 PTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYSCANTPGGFLCGC 2636
Query: 1369 P------SPRDCESGCASSP 1382
P C SG SP
Sbjct: 2637 PQGYFRAGQGHCVSGLGFSP 2656
Score = 474 bits (1219), Expect = e-133
Identities = 487/1746 (27%), Positives = 678/1746 (38%), Gaps = 378/1746 (21%)
Query: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFL----GEYCQ--HRDPC----EKNRCQNG 76
+C C N G CV G+ C+CPEG + G C +PC +++ C G
Sbjct: 872 ECESFPGVCPN-GRCVNTA-GSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDEC--G 927
Query: 77 GTCVAQAMLGKATC--------RCASGFTGEDCQYSTSHPC---FVSRPCLNG------- 118
T + + C C + E ++++ P F SR L+G
Sbjct: 928 VTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDV 987
Query: 119 -------GTC-HMLSRDT---YECTCQVGFT----GKECQWTDACLSHP--CANGSTCTT 161
G C H R+T + C C GF + C D C P C G TC
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG-TCVN 1046
Query: 162 VANQFSCKCL----TGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF---- 213
F C+C +GF K DV+EC GGTC N GSY+CQCP G
Sbjct: 1047 TPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTA 1106
Query: 214 TGQYCDSLYVPCAPSP--CVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQN 271
G C+ + C+ S C +G G F+C+C GF+ + + D R QN
Sbjct: 1107 KGTACEDI-DECSLSDGLCPHGQCVNVIG--AFQCSCHAGFQSTPDRQGCVDINECRVQN 1163
Query: 272 GGVCVDGVNT---YNCRCPPQWT----GQFCTEDVDECLLQPNACQNGGTCANRNGGYGC 324
GG V +NT Y C C ++ G+ C DVDEC P C G C N GG+ C
Sbjct: 1164 GGCDVHCINTEGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQ-GHCTNMPGGHRC 1221
Query: 325 VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP- 383
+C +G F + TC+D D C NP
Sbjct: 1222 LCYDG--------------FMATPDMRTCVD--------------------VDECDLNPH 1247
Query: 384 -CHKGALCDTNPLNGQYICTCPQGY---KGADCTEDVDECAMANSNPCEHAGKCVNTDGA 439
C G D G ++C C GY KGA DVDEC + N C+ C+N G+
Sbjct: 1248 ICLHG---DCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHN-CDSHASCLNIPGS 1303
Query: 440 FHCECLKGYAGPRCEM-DINECHSDP--CQNDATCLDKIGGFTCLCMPGF--KGVHCELE 494
F C CL G+ G E D++EC S C CL+ G + C C GF G CE +
Sbjct: 1304 FSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCE-D 1362
Query: 495 INECQSN-PCVNNGQCVDKVNRFQCLCPPGFTGP----VCQIDIDDCSSTPCLNGAKCID 549
+EC N +NGQC++ ++C C GF CQ D+D+C+ C +
Sbjct: 1363 RDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFGSCEN 1421
Query: 550 HPNGYECQCATGFT----GVLCEENIDNCDPDPCHHGQCQDGIDSYTCIC------NPGY 599
P + C C G+ G C + + DP C +G C + SY C C NP
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSG 1481
Query: 600 MGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQ--PGTSGVNCEINFDDCASNPCIHG 657
+G + + C+ +G C+ + G + +C + NPC
Sbjct: 1482 VGCV-DTRAGNCFLETHDRGD------SGISCSAEIGVGVTRASCCCSLGRAWGNPC--E 1532
Query: 658 IC-MDGINRYSCVC--SPGFTGQRCNI---DIDECASNP-CRKGATCINGVNGFRCICPE 710
+C M Y +C GF R + DIDEC P +G C+N F+C CP
Sbjct: 1533 LCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPP 1592
Query: 711 GPH---HPSCYSQVNECL--SNPCIHGNCTGGLSGYKCLCDAGWV----GINC-EVDKNE 760
G H H ++EC S C G C L Y C+C A ++ G NC ++ K+
Sbjct: 1593 GYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSV 1652
Query: 761 CLSNPCQNGGTCDN-------------------------------LVNGYRCTCKKGFKG 789
C + GTC N + Y+ C G
Sbjct: 1653 CFRH---YNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPG 1709
Query: 790 YNCQV------NIDECASNP--CLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCS--- 838
+ + +IDEC P C N G C + I + C C G N ++L C
Sbjct: 1710 FLTDIHTGKPLDIDECGEIPAICAN-GICINQIGSFRCECP---AGFNYNSILLACEDVD 1765
Query: 839 -----PNPCENAAVCKESPNFESYTCLCAPGWQ---GQRCTIDIDECISKP-CMNHGLCH 889
+PC+ A C P SY C C G++ G C + +EC P +HG C
Sbjct: 1766 ECGSRESPCQQNADCINIPG--SYRCKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCM 1822
Query: 890 NTQGSYMCECPPGFSGMDCEE---DIDDCLANPCQNGGSCMDGVNTFSCLCLPGF--TGD 944
+T+GSYMC C GF + DID+C PC N G+C + + +++CLC PGF T +
Sbjct: 1823 DTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN-GTCKNIIGSYNCLCFPGFVVTHN 1881
Query: 945 KCQTDMNEC---LSEPCKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINECTE--SS 995
D +EC + + C+ G C + S+ C CQ GF DG +C + NEC +
Sbjct: 1882 GDCVDFDECTTLVGQVCR-FGHCLNTAGSFHCLCQDGFELTADGKNCVDT-NECLSLAGT 1939
Query: 996 CFNGGTCVDGINSFSCLCPVGF--TGSFCLHEINECSSHP--CLNEGTCVDGLGTYRCSC 1051
C GTC + SF C+CP GF C+ +I+ECS P CL GTC + G+++C C
Sbjct: 1940 CL-PGTCQNLEGSFRCICPPGFQVQSDHCI-DIDECSEEPNLCL-FGTCTNSPGSFQCLC 1996
Query: 1052 PLGY----TGKNC-QTLVNLCSRSPCKNKGTCVQKKA----ESQCLCP----SGWAGAYC 1098
P G+ G C T + C G C KA +++C C GW
Sbjct: 1997 PPGFVLSDNGHRCFDTRQSFCFTR--FEAGKCSVPKAFNTTKTRCCCSKRPGEGWGD--- 2051
Query: 1099 DVPNVSCDIAASRRGVLVEHLCQH--------------------------SGVCINAGNT 1132
C++ + LC +GVC+N +
Sbjct: 2052 -----PCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGS 2106
Query: 1133 HYCQCPLGY----TGSYCEEQLDECA-SNPCQHGATCSDFIGGYRCECVPGYQG---VNC 1184
C+CP GY TG C + DEC+ +PC G TC++ IGG+ C C G++ + C
Sbjct: 2107 FRCECPFGYSLDFTGINCVD-TDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMTC 2164
Query: 1185 EYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG----TRGLLCEENIDDCARGPH-C-LNG 1238
E ++DEC P C + + C+CP G G +C + +D+CA G C G
Sbjct: 2165 E-DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD-VDECADGQQDCHARG 2222
Query: 1239 GQCMDRIGGYSCRCLPGF-----AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCR 1293
+C + IG ++C C PG +GE C D NEC + P C+ + C C
Sbjct: 2223 MECKNLIGTFACVCPPGMRPLPGSGEGCTDD-NECHAQPDLCVNG-RCVNTAGSFRCDCD 2280
Query: 1294 SAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRK 1353
F T Q PC V M CR S A ++ C C
Sbjct: 2281 EGFQPSPTLTECHDIRQGPCF----AEVLQTM-----CRSLSSSSEAVTRAEC----CCG 2327
Query: 1354 GEQCVHTASGPRC-FCPSPRDCESGCASSPCQHG------GSCHPQRQPPYYSC---QCA 1403
G + GPRC CP P + C HG G + + + C +C
Sbjct: 2328 GGR----GWGPRCELCPLP---GTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECI 2380
Query: 1404 PPFSGSRCELYTA-PPSTPPATCLS-QYCAD--KARDGVCDEACNSHACQWDGGDCSLTM 1459
RC P TCL C+ K +C S C G +
Sbjct: 2381 NSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRG---YLL 2437
Query: 1460 ENPWANCSSPLPCWDYINNQCDELC-NTV---------------ECLFDNFECQGNSKTC 1503
E C C +N C LC NTV + FDN EC C
Sbjct: 2438 EEDGRTCKDLDECTSRQHN-CQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPC 2496
Query: 1504 KYDKYC 1509
+C
Sbjct: 2497 GAHGHC 2502
Score = 451 bits (1159), Expect = e-126
Identities = 462/1649 (28%), Positives = 642/1649 (38%), Gaps = 329/1649 (19%)
Query: 77 GTCVAQAMLGKATCRCASGFT--GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQ 134
GTC + +G C CA GF ++ + C +S GTC + + ++EC C
Sbjct: 1000 GTC--RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC-VNTPGSFECECF 1056
Query: 135 VGFTG-----KECQWTDACLSHPC-ANGSTCTTVANQFSCKCLTGFT----GQKCETDVN 184
G+ K C D C P G TCT + C+C G G CE D++
Sbjct: 1057 PGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE-DID 1115
Query: 185 ECDIP-GHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGT---CRQTG 240
EC + G C HG C+N+ G++QC C GF V NGG C T
Sbjct: 1116 ECSLSDGLCPHG-QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINT- 1173
Query: 241 DFTFECNCLPGF----EGSTCERNIDDCP-NHRCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
+ ++ C+C G+ +G C ++D+C N R + G C + + C C + G
Sbjct: 1174 EGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQGHCTNMPGGHRCLC---YDGFMA 1229
Query: 296 TED------VDECLLQPNACQNGGTCANRNGGYGCVCVNGW----SGDDCSENIDDCAFA 345
T D VDEC L P+ C +G C N G + C C G+ CS+ +D+C
Sbjct: 1230 TPDMRTCVDVDECDLNPHICLHGD-CENTKGSFVCHCQLGYMVRKGATGCSD-VDECEVG 1287
Query: 346 --SCTPGSTCIDRVASFSCMCPEGKAG--LLCHLDDACISNPCHKGALCDTNPLNGQYIC 401
+C ++C++ SFSC C G G CH D C+S D + G Y C
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC 1347
Query: 402 TCPQGYKGADC-TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY---AGPRCEMDI 457
TC QG+ G ED DECA N + C++ G+C+N G + CEC G+ R D+
Sbjct: 1348 TCRQGFAGDGFFCEDRDECA-ENVDLCDN-GQCLNAPGGYRCECEMGFDPTEDHRACQDV 1405
Query: 458 NECHSDPCQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQSNPCVNNGQCVDKV 513
+EC +C + G F C+C G++ G +C +INEC NG C++
Sbjct: 1406 DECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCT-DINECADPVNCINGVCINTP 1464
Query: 514 NRFQCLCPPGFTGPVCQIDIDDCSSTPCL--------NGAKCIDH----PNGYECQCATG 561
+ C CP F + D + C +G C C C+ G
Sbjct: 1465 GSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLG 1524
Query: 562 FT-GVLCE-----------------------------ENIDNCD--PDPCHHGQCQDGID 589
G CE E+ID C P C G C +
Sbjct: 1525 RAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFG 1584
Query: 590 SYTCICNPGYMGA----ICSDQIDECYS-SPCLNDGRCIDLVNGYQCNCQPGTSGVNCEI 644
S+ C C PGY + IC D IDEC + S G C + + Y C C VN
Sbjct: 1585 SFQCECPPGYHLSEHTRICED-IDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGN 1643
Query: 645 NFDDCASNPCI---HGICMD----GINRYSCVCSPGFTGQRCNIDIDECAS--NPCRKGA 695
N D + C +G C + + R C CS GQ N + C + +P +
Sbjct: 1644 NCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNI-GQAWNRPCEACPTPISPDYQ-I 1701
Query: 696 TCINGVNGFRCICPEGPHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW---- 749
C N GF H ++EC P C +G C + ++C C AG+
Sbjct: 1702 LCGNQAPGFLTDI-----HTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNS 1756
Query: 750 VGINCEVDKNECLS--NPCQNGGTCDNLVNGYRCTCKKGFK---GYNCQVNIDECASNPC 804
+ + CE D +EC S +PCQ C N+ YRC C +G+K G C V +EC P
Sbjct: 1757 ILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGAC-VGRNECREIPN 1814
Query: 805 L-NQGTCFDDISGYTCHCVLPYTGKNCQTV---LAPCSPNPCENAAVCKESPNFESYTCL 860
+ + G C D Y C C + QT+ + C PC N CK SY CL
Sbjct: 1815 VCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT-CKNI--IGSYNCL 1871
Query: 861 CAPGW---QGQRCTIDIDEC---ISKPCMNHGLCHNTQGSYMCECPPGFS----GMDCEE 910
C PG+ C +D DEC + + C G C NT GS+ C C GF G +C
Sbjct: 1872 CFPGFVVTHNGDC-VDFDECTTLVGQVC-RFGHCLNTAGSFHCLCQDGFELTADGKNCV- 1928
Query: 911 DIDDCL--ANPCQNGGSCMDGVNTFSCLCLPGFT--GDKCQTDMNECLSEP--CKNGGTC 964
D ++CL A C G +C + +F C+C PGF D C D++EC EP C G TC
Sbjct: 1929 DTNECLSLAGTCLPG-TCQNLEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLFG-TC 1985
Query: 965 SDYVNSYTCKCQAGF----DGVHCENN----------INECTESSCFN------------ 998
++ S+ C C GF +G C + +C+ FN
Sbjct: 1986 TNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRP 2045
Query: 999 ----GGTCV----DGINSFSCLCPVGFTG----SFCLHEINECSSHP--CLNEGTCVDGL 1044
G C +G +F LCP G ++NEC+ +P C N G CV+
Sbjct: 2046 GEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTN-GVCVNTD 2104
Query: 1045 GTYRCSCPLGY----TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDV 1100
G++RC CP GY TG NC PC +GTC +C C G+
Sbjct: 2105 GSFRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTNVIGGFECACADGFE------ 2157
Query: 1101 PNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT----GSYCEEQLDECASN 1156
P + L LC C N ++ C CP GYT G+ C + +DECA
Sbjct: 2158 PGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGYTLREDGAMCRD-VDECADG 2214
Query: 1157 P--CQ-HGATCSDFIGGYRCECVPGYQ-----GVNCEYEVDECQNQP--CQNGGTCIDLV 1206
C G C + IG + C C PG + G C + +EC QP C NG C++
Sbjct: 2215 QQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDD-NECHAQPDLCVNG-RCVNTA 2272
Query: 1207 NHFKCSCPPGTRGLLCEENIDDCARGPH------------------------CLNGGQCM 1242
F+C C G + D +GP C GG+
Sbjct: 2273 GSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGR-- 2330
Query: 1243 DRIGGYSCRC----LPGFAGER----------CEG-DINEC--LSNPCSSEGSLDCIQLT 1285
G+ RC LPG + R EG D++EC L++ C+ +CI
Sbjct: 2331 ----GWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHG---ECINSL 2383
Query: 1286 NDYLCVCRSAFTGRHCETF---VDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF----S 1338
+ C C++ +T T +D C Q+P C N F+C CP G+
Sbjct: 2384 GSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLC---KNTKGSFLCSCPRGYLLEED 2440
Query: 1339 GARCQS--SCGQVKCRKGEQCVHTASGPRCFCPSP-----RDC----ESGCASSPCQHGG 1387
G C+ C + CV+T C CP + C E PC G
Sbjct: 2441 GRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHG 2500
Query: 1388 SCHPQRQPPYYSCQCAPPF----SGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEAC 1443
CH P + C+C F SG CE P C C
Sbjct: 2501 HCH--NTPGSFRCECHQGFTLVSSGHGCE--DVNECDGPHRC----------QHGCQNQL 2546
Query: 1444 NSHACQWDGGDCSLTMENPWANCSSPLPC 1472
+ C G T + WA C C
Sbjct: 2547 GGYRCSCPQG---FTQHSQWAQCVDENEC 2572
Score = 447 bits (1151), Expect = e-125
Identities = 436/1512 (28%), Positives = 609/1512 (40%), Gaps = 325/1512 (21%)
Query: 90 CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACL 149
C CA G C S C VS C+NGGTC S C CQ G+TG C
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVS--CMNGGTCRGAS-----CLCQKGYTGTVCG--QPIC 151
Query: 150 SHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI-----PGHCQHGGTCLNLPGS 204
C NG C C C+ GF G +CE D P CQH T L +
Sbjct: 152 DRGCHNGGRCI---GPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKA 208
Query: 205 YQCQCPQGFTGQYCDSLYVPCAPSPCVNG-------GTCRQTGDFTFECNCLPGFEGSTC 257
C G C+ P P PC G G C+ EC +PG
Sbjct: 209 LCCATVGRAWGLPCE--LCPAQPHPCRRGFIPNIHTGACQDVD----ECQAVPGL----- 257
Query: 258 ERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECL-LQPNACQN---GG 313
CQ GG CV+ V +++CRCP G ++ C + AC + GG
Sbjct: 258 -----------CQ-GGSCVNMVGSFHCRCP---VGHRLSDSSAACEDYRAGACFSVLFGG 302
Query: 314 TCANRNGGY----GCVCVNG--WSGDDCSENIDDCAFASCTPGST------CIDRV---- 357
CA G+ C C G W+ E C P + C R+
Sbjct: 303 RCAGDLAGHYTRRQCCCDRGRCWAAGPVPE--------LCPPRGSNEFQQLCAQRLPLLP 354
Query: 358 ------------ASFSCMCPEGKAGLLCHLDDA------------------------C-- 379
S P G A L H DA C
Sbjct: 355 GHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRH 414
Query: 380 ISNPCHKGALCDTNPLNGQYICTCPQGYK---GADCTEDVDECAMANSNPCEHAGKCVNT 436
+N C G P Y C C GY +C DVDEC S+PC H G CVN
Sbjct: 415 FTNLCLNGRCL---PTPSSYRCECNVGYTQDVRGECI-DVDEC---TSSPCHH-GDCVNI 466
Query: 437 DGAFHCECLKGY-AGPRCE--MDINEC-HSDPCQNDATCLDKIGGFTCLCMPGFK----G 488
G +HC C G+ A P + +D++EC S + C++ G F C+C GF+ G
Sbjct: 467 PGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDG 526
Query: 489 VHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTP--CL 542
+C ++ NEC ++ NG C+++ F CLC PGF G C +DID+C TP C+
Sbjct: 527 KNC-VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC-MDIDEC-QTPGICV 583
Query: 543 NGAKCIDHPNGYECQC----ATGFTGVLCEE----------------------------- 569
NG C + + CQC A G G +C +
Sbjct: 584 NG-HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSEC 642
Query: 570 ---NIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP--CLNDGRCID 624
N D+ +PC +D + + +C+ G I+EC P C N G C +
Sbjct: 643 CCANPDHGFGEPCQLCPAKDSAE-FQALCSSGLGITTDGRDINECALDPEVCAN-GVCEN 700
Query: 625 LVNGYQCNC----QPGTSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGF---- 674
L Y+C C + G SG +C + D+CA N C +G C + YSC C PGF
Sbjct: 701 LRGSYRCVCNLGYEAGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQ 759
Query: 675 TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPH-HPS-----------CYSQVN 722
+ C D+DEC S+PC G C N + C C G PS C+ ++
Sbjct: 760 DTEICK-DVDECLSSPCVSG-VCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQ 817
Query: 723 EC-----LSNPCIHGNC---TGGLSGYKC-------LCDAGW---VGINCEVDKNECLSN 764
E L + C G G C C G+ G+ C+ D NEC S
Sbjct: 818 ESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESF 876
Query: 765 P--CQNGGTCDNLVNGYRCTCKKGF----KGYNC-QVNIDECASNPCLNQGTCFDDISG- 816
P C N G C N +RC C +G G C V ++ C ++ C + G
Sbjct: 877 PGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLR--WDEDECGVTLPGK 933
Query: 817 ----YTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTI 872
C + G C+ A P E A++C F S L G+
Sbjct: 934 YRMDVCCCSIGAVWGVECE---ACPDPESLEFASLCPRGLGFASRDFL-----SGRPFYK 985
Query: 873 DIDECISKPCM-NHGLCHNTQGSYMCECPPGFSGMDCEE----DIDDCLANPCQNG-GSC 926
D++EC P + HG C NT GS+ C C GF+ +D +E DID+C +P G G+C
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFA-LDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 927 MDGVNTFSCLCLPGFTGD----KCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGFD 980
++ +F C C PG+ K D++EC +P C+ GGTC++ SY C+C G +
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCR-GGTCTNTDGSYKCQCPPGHE 1103
Query: 981 ----GVHCENNINECTES-SCFNGGTCVDGINSFSCLCPVGFTGS----FCLHEINECSS 1031
G CE +I+EC+ S G CV+ I +F C C GF + C+ +INEC
Sbjct: 1104 LTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCV-DINECRV 1161
Query: 1032 HPCLNEGTCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSP-CKNKGTCVQKKAESQ 1086
+ C++ G+YRCSC GY+ G+ C V+ C +P ++G C +
Sbjct: 1162 QNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACAD-VDECEENPRVCDQGHCTNMPGGHR 1220
Query: 1087 CLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY---TG 1143
CLC G + P++ + L H+C H G C N + C C LGY G
Sbjct: 1221 CLCYDG----FMATPDMRTCVDVDECD-LNPHICLH-GDCENTKGSFVCHCQLGYMVRKG 1274
Query: 1144 SYCEEQLDEC--ASNPCQHGATCSDFIGGYRCECVPGYQGVNCE-YEVDEC--QNQPCQN 1198
+ +DEC + C A+C + G + C C+PG+ G E +++DEC Q C
Sbjct: 1275 ATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSP 1334
Query: 1199 GGTCIDLVNHFKCSCPPGTR--GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256
G C+++ ++C+C G G CE+ D+CA + GQC++ GGY C C GF
Sbjct: 1335 RGDCLNVPGSYRCTCRQGFAGDGFFCEDR-DECAENVDLCDNGQCLNAPGGYRCECEMGF 1393
Query: 1257 ---AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCP 1309
R D++EC + GS C L + C+C + G +C +
Sbjct: 1394 DPTEDHRACQDVDECAQGNLCAFGS--CENLPGMFRCICNGGYELDRGGGNCTDINECAD 1451
Query: 1310 QMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCP 1369
+ C+NG V N P ++C CP F G CV T +G CF
Sbjct: 1452 PVNCING----VCINTPGSYLCSCPQDFE-----------LNPSGVGCVDTRAG-NCFLE 1495
Query: 1370 SPRDCESGCASS 1381
+ +SG + S
Sbjct: 1496 THDRGDSGISCS 1507
Score = 443 bits (1140), Expect = e-124
Identities = 481/1760 (27%), Positives = 685/1760 (38%), Gaps = 413/1760 (23%)
Query: 35 CVNEGMCVTYHNGTGYCKCPEGFL----GEYCQHRDPCEKNRCQNGGTCVAQAMLGKATC 90
CVN G+C+ +G+ C C GFL G YC D C+ G C G C
Sbjct: 541 CVN-GVCLN-EDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTE--GSFRC 596
Query: 91 RCASGFT-GEDCQYST-SHPCFVSRPCLNGGTCHMLSRDTY---ECTC---QVGFTGKEC 142
+C G G D + +H + G+C T EC C GF G+ C
Sbjct: 597 QCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGF-GEPC 655
Query: 143 QWTDA-------------------------CLSHP--CANGSTCTTVANQFSCKCLTGF- 174
Q A C P CANG C + + C C G+
Sbjct: 656 QLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANG-VCENLRGSYRCVCNLGYE 714
Query: 175 ---TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAP 227
+G+ C TDV+EC + G C N PGSY C CP GF + C + C
Sbjct: 715 AGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDV-DECLS 772
Query: 228 SPCVNGGTCRQTGDFTFECN-----------CLPGFEG--------STCERNI------D 262
SPCV+G G +T +C CL +G S CE N+
Sbjct: 773 SPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRS 832
Query: 263 DC----------PNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNG 312
+C P RC+ C G + TG C +DV+EC P C N
Sbjct: 833 ECCATLGAAWGSPCERCEIDPACARGF--------ARMTGVTC-DDVNECESFPGVCPN- 882
Query: 313 GTCANRNGGYGCVCVNG---------------------WSGDDCSENI------DDCAFA 345
G C N G + C C G W D+C + D C
Sbjct: 883 GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCC-- 940
Query: 346 SCTPGS-------TCID-RVASFSCMCPEG--------KAGLLCHLD-DACISNP--CHK 386
C+ G+ C D F+ +CP G +G + D + C P C
Sbjct: 941 -CSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTH 999
Query: 387 GALCDTNPLNGQYICTCPQGY----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHC 442
G +T G + C C G+ + +CT D+DEC + + + C G CVNT G+F C
Sbjct: 1000 GTCRNT---VGSFHCACAGGFALDAQERNCT-DIDECRI-SPDLCGQ-GTCVNTPGSFEC 1053
Query: 443 ECLKGYAG-----PRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGF----KGVHC 491
EC GY C MD++EC DP C+ TC + G + C C PG KG C
Sbjct: 1054 ECFPGYESGFMLMKNC-MDVDECARDPLLCRG-GTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Query: 492 ELEINECQ-SNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQ---IDIDDCSSTPCLNGAKC 547
E +I+EC S+ +GQCV+ + FQC C GF + +DI++C C
Sbjct: 1112 E-DIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHC 1170
Query: 548 IDHPNGYECQCATGFT----GVLCEENIDNCDPDP--CHHGQCQDGIDSYTCICNPGYMG 601
I+ Y C C G++ G C + +D C+ +P C G C + + C+C G+M
Sbjct: 1171 INTEGSYRCSCGQGYSLMPDGRACAD-VDECEENPRVCDQGHCTNMPGGHRCLCYDGFMA 1229
Query: 602 A----ICSDQIDECYSSP--CLNDGRCIDLVNGYQCNCQ------PGTSGVN----CEIN 645
C D +DEC +P CL+ G C + + C+CQ G +G + CE+
Sbjct: 1230 TPDMRTCVD-VDECDLNPHICLH-GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 646 FDDCASNPCIHGICMDGINRYSCVCSPGFTGQ--RCNIDIDECAS--NPCRKGATCINGV 701
+C S H C++ +SC C PG+ G C+ D+DEC S + C C+N
Sbjct: 1288 GHNCDS----HASCLNIPGSFSCRCLPGWVGDGFECH-DLDECVSQEHRCSPRGDCLNVP 1342
Query: 702 NGFRCICPEGPHHPSCYSQ-VNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGIN----C 754
+RC C +G + + +EC N C +G C GY+C C+ G+ C
Sbjct: 1343 GSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRAC 1402
Query: 755 EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASNPCLNQGTC 810
+ D +EC G+C+NL +RC C G++ G NC +I+ECA G C
Sbjct: 1403 Q-DVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNC-TDINECADPVNCINGVC 1460
Query: 811 FDDISGYTCHCVLPY---------------------------------------TGKNCQ 831
+ Y C C + T +C
Sbjct: 1461 INTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCC 1520
Query: 832 TVLAPCSPNPCENAAVCKESPNFESYTCLC--APGWQGQRCTI---DIDECISKPCM-NH 885
L NPCE + N Y LC G+Q R T+ DIDEC P +
Sbjct: 1521 CSLGRAWGNPCELCPMA----NTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQG 1576
Query: 886 GLCHNTQGSYMCECPPGFSGMD----CEEDIDDCLANPCQNG-GSCMDGVNTFSCLCLPG 940
G C NT GS+ CECPPG+ + C EDID+C + G G+C + + ++C+C
Sbjct: 1577 GDCVNTFGSFQCECPPGYHLSEHTRIC-EDIDECSTHSGICGPGTCYNTLGNYTCVCPAE 1635
Query: 941 FT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVH----CENNINECT 992
+ G+ C DM + + NG TC+ + F+ C NI +
Sbjct: 1636 YLQVNGGNNCM-DMRKSVCFRHYNG----------TCQNELAFNVTRKMCCCSYNIGQAW 1684
Query: 993 ESSCFNGGTCVDGIN-SFSCLCPVGFTGSFC-LH-----EINECSSHP--CLNEGTCVDG 1043
C C I+ + LC G +H +I+EC P C N G C++
Sbjct: 1685 NRPC---EACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICAN-GICINQ 1740
Query: 1044 LGTYRCSCPLGYTGKN----CQTLVNLCSR-SPCKNKGTCVQKKAESQCLCPSGW---AG 1095
+G++RC CP G+ + C+ + SR SPC+ C+ +C C G+ G
Sbjct: 1741 IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG 1800
Query: 1096 AYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEE---QLDE 1152
C N +I ++C H G C++ ++ C C G+ S + +DE
Sbjct: 1801 GACVGRNECREI---------PNVCSH-GDCMDTEGSYMCLCHRGFQASADQTLCMDIDE 1850
Query: 1153 CASNPCQHGATCSDFIGGYRCECVPGY---QGVNCEYEVDECQ---NQPCQNGGTCIDLV 1206
C PC +G TC + IG Y C C PG+ +C + DEC Q C+ G C++
Sbjct: 1851 CDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDC-VDFDECTTLVGQVCR-FGHCLNTA 1907
Query: 1207 NHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDIN 1266
F C LC++ + A G +C++ +C+ G CLPG
Sbjct: 1908 GSFHC---------LCQDGFELTADGKNCVDTNECLSLAG----TCLPG----------- 1943
Query: 1267 ECLSNPCSSEGSLDCIQLTNDYLCVCRSAF--TGRHCETFVDVCPQMP--CLNGGTCAVA 1322
C L + C+C F HC +D C + P CL GTC
Sbjct: 1944 -------------TCQNLEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCL-FGTC--- 1985
Query: 1323 SNMPDGFICRCPPGF----SGARC----QSSCGQVKCRKGEQCVHTA---SGPRCFCPSP 1371
+N P F C CPPGF +G RC QS C + G+ V A + RC C
Sbjct: 1986 TNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFC-FTRFEAGKCSVPKAFNTTKTRCCCSKR 2044
Query: 1372 RDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCA 1431
G C GS Q P + P SR ++ + P C + C
Sbjct: 2045 PGEGWGDPCELCPQEGSAAFQELCP-FGHGAVPGPDDSREDVNECAEN--PGVCTNGVCV 2101
Query: 1432 DKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVEC-L 1490
+ C E ++ + G +C T E CS PC C + EC
Sbjct: 2102 NTDGSFRC-ECPFGYSLDFTGINCVDTDE-----CSVGHPCG---QGTCTNVIGGFECAC 2152
Query: 1491 FDNFECQGNSKTCKYDKYCA 1510
D FE G TC+ C+
Sbjct: 2153 ADGFE-PGLMMTCEDIDECS 2171
Score = 427 bits (1097), Expect = e-119
Identities = 461/1695 (27%), Positives = 639/1695 (37%), Gaps = 463/1695 (27%)
Query: 19 CAAPAHALQCRD-----GYEPCV--------NEGMCVTYHNGTGYCKCPEGFLGEYC--Q 63
C + HA C G CV EG C + C C +G L C
Sbjct: 60 CGSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFC----SQPNLCTCADGTLAPSCGVS 115
Query: 64 HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHM 123
C + C NGGTC A+C C G+TG C R C NGG C
Sbjct: 116 RGSGCSVS-CMNGGTCRG------ASCLCQKGYTGTVCGQP-----ICDRGCHNGGRCIG 163
Query: 124 LSRDTYECTCQVGFTGKECQW---TDACLSHP-------------CANGSTCTTVANQFS 167
+R C C GF G +C+ T C C C TV +
Sbjct: 164 PNR----CACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWG 219
Query: 168 --CK--------CLTGF-----TGQKCETDVNECD-IPGHCQHGGTCLNLPGSYQCQCPQ 211
C+ C GF TG C+ DV+EC +PG CQ GG+C+N+ GS+ C+CP
Sbjct: 220 LPCELCPAQPHPCRRGFIPNIHTGA-CQ-DVDECQAVPGLCQ-GGSCVNMVGSFHCRCPV 276
Query: 212 GFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQN 271
G + DS A G C F C G R C RC
Sbjct: 277 GH--RLSDS----SAACEDYRAGACFSV---LFGGRCAGDLAGHYTRRQC-CCDRGRCWA 326
Query: 272 GGVCVDGVNTYNCRCPPQWTGQF---CTE-------------------------DVDECL 303
G + CPP+ + +F C + +
Sbjct: 327 AGPVPE-------LCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPAR 379
Query: 304 LQPNACQNGG--TCANRNGGYGCVCVNGWSGDDCSENIDDCA-FASCTPGSTCIDRVASF 360
L P+ G + N G +N + ID C F + C+ +S+
Sbjct: 380 LNPHGSDARGIPSLGPGNSNIGTATLN--------QTIDICRHFTNLCLNGRCLPTPSSY 431
Query: 361 SCMCPEGKAGLL---CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTE--- 414
C C G + C D C S+PCH G D + G Y C C G++ +
Sbjct: 432 RCECNVGYTQDVRGECIDVDECTSSPCHHG---DCVNIPGTYHCRCYPGFQATPTRQACV 488
Query: 415 DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDPCQNDAT 470
DVDEC + S H G+CVNT+G+F C C G+ G C +D NEC + +
Sbjct: 489 DVDECIV--SGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGV 545
Query: 471 CLDKIGGFTCLCMPGF---KGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFT-- 525
CL++ G F+CLC PGF G H ++I+ECQ+ NG C + F+C C G
Sbjct: 546 CLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVG 605
Query: 526 --GPVC-----------QIDIDDCSS--TPCLNGAKCI----DHPNGYECQ--------- 557
G VC I+ C+ + ++C DH G CQ
Sbjct: 606 TDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAE 665
Query: 558 ----CATGFTGVLCEENIDNC--DPDPCHHGQCQDGIDSYTCICNPGY----MGAICSDQ 607
C++G +I+ C DP+ C +G C++ SY C+CN GY G C+D
Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD- 724
Query: 608 IDECYSSPCLND-GRCIDLVNGYQCNCQPGTS-GVNCEI--NFDDCASNPCIHGICMDGI 663
+DEC + L D G C + Y C+C PG + EI + D+C S+PC+ G+C +
Sbjct: 725 VDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLA 784
Query: 664 NRYSCVCSPG---------------------FTGQRCNIDI------DECAS-------N 689
Y+C C PG RC +++ EC + +
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS 844
Query: 690 PCRK---------------GAT------------------CINGVNGFRCICPEGPHHPS 716
PC + G T C+N FRC CPEG +
Sbjct: 845 PCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDA 904
Query: 717 CYSQVNECLSNPCI----HGNCTGGLSG-YK---CLCDAGWV-GINCEV----------- 756
+ PC C L G Y+ C C G V G+ CE
Sbjct: 905 SGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFAS 964
Query: 757 ---------------------DKNECLSNP--CQNGGTCDNLVNGYRCTCKKGF----KG 789
D NEC P C + GTC N V + C C GF +
Sbjct: 965 LCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTH-GTCRNTVGSFHCACAGGFALDAQE 1023
Query: 790 YNCQVNIDECASNPCL-NQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVC 848
NC +IDEC +P L QGTC + + C C
Sbjct: 1024 RNC-TDIDECRISPDLCGQGTCVNTPGSFECECF-------------------------- 1056
Query: 849 KESPNFESYTCLCAPGWQGQRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGF---- 903
P +ES G+ + +D+DEC P + G C NT GSY C+CPPG
Sbjct: 1057 ---PGYES-------GFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTA 1106
Query: 904 SGMDCEEDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGF--TGDK--CQTDMNECLSEPC 958
G C EDID+C L++ G C++ + F C C GF T D+ C D+NEC
Sbjct: 1107 KGTAC-EDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGC-VDINEC---RV 1161
Query: 959 KNGGT---CSDYVNSYTCKCQAGF----DGVHCENNINECTES-SCFNGGTCVDGINSFS 1010
+NGG C + SY C C G+ DG C +++EC E+ + G C +
Sbjct: 1162 QNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQGHCTNMPGGHR 1220
Query: 1011 CLCPVGFTGS----FCLHEINECSSHP--CLNEGTCVDGLGTYRCSCPLGY---TGKNCQ 1061
CLC GF + C+ +++EC +P CL+ G C + G++ C C LGY G
Sbjct: 1221 CLCYDGFMATPDMRTCV-DVDECDLNPHICLH-GDCENTKGSFVCHCQLGYMVRKGATGC 1278
Query: 1062 TLVNLC--SRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHL 1119
+ V+ C C + +C+ C C GW G + ++ V EH
Sbjct: 1279 SDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLD-------ECVSQEHR 1331
Query: 1120 CQHSGVCINAGNTHYCQCPLGYTGS--YCEEQLDECASNP--CQHGATCSDFIGGYRCEC 1175
C G C+N ++ C C G+ G +CE++ DECA N C +G C + GGYRCEC
Sbjct: 1332 CSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDR-DECAENVDLCDNG-QCLNAPGGYRCEC 1389
Query: 1176 VPGYQGVN----CEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG---TRGLLCEENIDD 1228
G+ C+ +VDEC G+C +L F+C C G RG +I++
Sbjct: 1390 EMGFDPTEDHRACQ-DVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINE 1448
Query: 1229 CARGPHCLNGGQCMDRIGGYSCRCLPGF--------------------------AGERCE 1262
CA +C+N G C++ G Y C C F +G C
Sbjct: 1449 CADPVNCIN-GVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCS 1507
Query: 1263 GDINE-------CLS------NPCSSEGSLDCIQLTNDY--LCVCRSAFTGRHCETF--- 1304
+I C S NPC L + T +Y LC F
Sbjct: 1508 AEIGVGVTRASCCCSLGRAWGNPC----ELCPMANTTEYRTLCPGGEGFQPNRITVILED 1563
Query: 1305 VDVCPQMPCL-NGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVK--------CRKGE 1355
+D C ++P L GG C N F C CPPG+ + C + C G
Sbjct: 1564 IDECQELPGLCQGGDCV---NTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPG- 1619
Query: 1356 QCVHTASGPRCFCPS 1370
C +T C CP+
Sbjct: 1620 TCYNTLGNYTCVCPA 1634
Score = 423 bits (1088), Expect = e-118
Identities = 425/1515 (28%), Positives = 616/1515 (40%), Gaps = 314/1515 (20%)
Query: 115 CLNGGTCHMLSRDTYECTCQVGFTGK---ECQWTDACLSHPCANGSTCTTVANQFSCKCL 171
CLNG + + +Y C C VG+T EC D C S PC +G C + + C+C
Sbjct: 419 CLNGRC--LPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD-CVNIPGTYHCRCY 475
Query: 172 TGF----TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYCDSLYV 223
GF T Q C DV+EC + G H G C+N GS+QC C GF G+ C +
Sbjct: 476 PGFQATPTRQAC-VDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVD-HN 533
Query: 224 PCAPSP-CVNGGTCRQTGDFTFECNCLPGF---EGSTCERNIDDCPNHRCQNGGVCVDG- 278
CA S CVNG + G +F C C PGF G +ID+ CQ G+CV+G
Sbjct: 534 ECATSTMCVNGVCLNEDG--SFSCLCKPGFLLAPGGHYCMDIDE-----CQTPGICVNGH 586
Query: 279 -VNTY-NCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCAN---RNGGYGCV----CVNG 329
NT + RC +CL +G C + R+ YG + C
Sbjct: 587 CTNTEGSFRC--------------QCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARP 632
Query: 330 WSG----DDCSENIDDCAFASCTPGSTCIDR-VASFSCMCPEGKAGLLCHLD-DACISNP 383
+ G +C D F P C + A F +C G D + C +P
Sbjct: 633 FPGTVTKSECCCANPDHGFGE--PCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDP 690
Query: 384 --CHKGALCDTNPLNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTD 437
C G +C+ L G Y C C GY+ G DCT DVDECA+ NS C++ G C N+
Sbjct: 691 EVCANG-VCEN--LRGSYRCVCNLGYEAGASGKDCT-DVDECAL-NSLLCDN-GWCQNSP 744
Query: 438 GAFHCECLKGY---AGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK----GVH 490
G++ C C G+ D++EC S PC + C + G +TC C PG + G
Sbjct: 745 GSYSCSCPPGFHFWQDTEICKDVDECLSSPCVS-GVCRNLAGSYTCKCGPGSRLDPSGTF 803
Query: 491 CELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDH 550
C L+ + G C K+ + C G + + C++ G+ C
Sbjct: 804 C-LDSTK---------GTCWLKIQ--ESRCEVNLQG--ASLRSECCATLGAAWGSPC--E 847
Query: 551 PNGYECQCATGF---TGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----G 601
+ CA GF TGV C++ ++ C+ P C +G+C + S+ C C G M G
Sbjct: 848 RCEIDPACARGFARMTGVTCDD-VNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Query: 602 AICSD-QIDECYSSPCLNDGRC-IDLVNGYQ---CNCQPGTS-GVNCEI----------- 644
+C D +++ C+ ++ C + L Y+ C C G GV CE
Sbjct: 907 RLCVDVRLEPCFLR--WDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFAS 964
Query: 645 ---------------------NFDDCASNP--CIHGICMDGINRYSCVCSPGF---TGQR 678
+ ++C P C HG C + + + C C+ GF +R
Sbjct: 965 LCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER 1024
Query: 679 CNIDIDECASNP--CRKGATCINGVNGFRCICPEGPHH-----PSCYSQVNECLSNP--C 729
DIDEC +P C +G TC+N F C C G +C V+EC +P C
Sbjct: 1025 NCTDIDECRISPDLCGQG-TCVNTPGSFECECFPGYESGFMLMKNC-MDVDECARDPLLC 1082
Query: 730 IHGNCTGGLSGYKCLCDAGW----VGINCEVDKNEC-LSNPCQNGGTCDNLVNGYRCTCK 784
G CT YKC C G G CE D +EC LS+ G C N++ ++C+C
Sbjct: 1083 RGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCH 1141
Query: 785 KGFKG----YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT----GKNCQTVLAP 836
GF+ C V+I+EC C + Y C C Y+ G+ C V
Sbjct: 1142 AGFQSTPDRQGC-VDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADV-DE 1199
Query: 837 CSPNP--CENAAVCKESPNFESYTCLCAPGWQG---QRCTIDIDECISKP--CMNHGLCH 889
C NP C+ C P + CLC G+ R +D+DEC P C+ HG C
Sbjct: 1200 CEENPRVCDQGH-CTNMPG--GHRCLCYDGFMATPDMRTCVDVDECDLNPHICL-HGDCE 1255
Query: 890 NTQGSYMCECPPGF---SGMDCEEDIDDCL--ANPCQNGGSCMDGVNTFSCLCLPGFTGD 944
NT+GS++C C G+ G D+D+C + C + SC++ +FSC CLPG+ GD
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGD 1315
Query: 945 --KCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF--DGVHCENNINECTES-SCF 997
+C D++EC+S+ C G C + SY C C+ GF DG CE+ +EC E+
Sbjct: 1316 GFECH-DLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDR-DECAENVDLC 1373
Query: 998 NGGTCVDGINSFSCLCPVGFTGS---FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLG 1054
+ G C++ + C C +GF + +++EC+ G+C + G +RC C G
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Query: 1055 YT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAAS 1110
Y G NC T +N C+ G C+ C CP + + V C +
Sbjct: 1434 YELDRGGGNC-TDINECADPVNCINGVCINTPGSYLCSCPQDFE---LNPSGVGCVDTRA 1489
Query: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGG 1170
L H SG+ +A + +G T + C L NPC+ +
Sbjct: 1490 GNCFLETHDRGDSGISCSA------EIGVGVTRASCCCSLGRAWGNPCELCPMAN--TTE 1541
Query: 1171 YRCECVPGYQGVNCE------YEVDECQNQP--CQNGGTCIDLVNHFKCSCPPG----TR 1218
YR C PG +G ++DECQ P CQ GG C++ F+C CPPG
Sbjct: 1542 YRTLC-PGGEGFQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGYHLSEH 1599
Query: 1219 GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER------------------ 1260
+CE+ ID+C+ G C + +G Y+C C +
Sbjct: 1600 TRICED-IDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYN 1658
Query: 1261 -----------------CEGDINECLSNPCSSEGSLDC-IQLTNDYLCVC--------RS 1294
C +I + + PC + C ++ DY +C
Sbjct: 1659 GTCQNELAFNVTRKMCCCSYNIGQAWNRPCEA-----CPTPISPDYQILCGNQAPGFLTD 1713
Query: 1295 AFTGRHCETFVDVCPQMP--CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQV--- 1349
TG+ + +D C ++P C NG + N F C CP GF+ +C V
Sbjct: 1714 IHTGKPLD--IDECGEIPAICANG----ICINQIGSFRCECPAGFNYNSILLACEDVDEC 1767
Query: 1350 -----KCRKGEQCVHTASGPRCFCPSPRDCESG--------CASSP--CQHGGSCHPQRQ 1394
C++ C++ RC C G C P C HG +
Sbjct: 1768 GSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGS 1827
Query: 1395 PPYYSCQCAPPFSGS 1409
Y C C F S
Sbjct: 1828 ---YMCLCHRGFQAS 1839
Score = 360 bits (923), Expect = 1e-98
Identities = 391/1436 (27%), Positives = 545/1436 (37%), Gaps = 317/1436 (22%)
Query: 345 ASCTPG-------STCIDRVASFSC---MCPEGKAGLLCHLDDACISNPC--HKGALCDT 392
A C PG S C+ + +C C + LC D ++ C +G+ C
Sbjct: 66 AYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPN---LCTCADGTLAPSCGVSRGSGCSV 122
Query: 393 NPLNGQYI----CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY 448
+ +NG C C +GY G C + + + C + G+C+ G C C+ G+
Sbjct: 123 SCMNGGTCRGASCLCQKGYTGTVCGQPICD------RGCHNGGRCI---GPNRCACVYGF 173
Query: 449 AGPRCEMD------INECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCEL--------- 493
GP+CE D + + CQ+ T L C + G+ CEL
Sbjct: 174 MGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCR 233
Query: 494 -------------EINECQSNPCV-NNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST 539
+++ECQ+ P + G CV+ V F C CP G +D +
Sbjct: 234 RGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAG 293
Query: 540 PCLN---GAKCIDHPNGY----ECQC------ATGFTGVLCEENIDNCDPDPCH------ 580
C + G +C G+ +C C A G LC N C
Sbjct: 294 ACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLL 353
Query: 581 -----------------------------HGQCQDGIDSYTCICNPGYMG---AICSDQI 608
HG GI S PG A + I
Sbjct: 354 PGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSL----GPGNSNIGTATLNQTI 409
Query: 609 DEC--YSSPCLNDGRCIDLVNGYQCNCQPG-TSGVNCE-INFDDCASNPCIHGICMDGIN 664
D C +++ CLN GRC+ + Y+C C G T V E I+ D+C S+PC HG C++
Sbjct: 410 DICRHFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPG 468
Query: 665 RYSCVCSPGF----TGQRCNIDIDEC--ASNPCRKGATCINGVNGFRCICPEG----PHH 714
Y C C PGF T Q C +D+DEC + C G C+N F+C+C G P
Sbjct: 469 TYHCRCYPGFQATPTRQAC-VDVDECIVSGGLCHLG-RCVNTEGSFQCVCNAGFELSPDG 526
Query: 715 PSCYSQVNEC-LSNPCIHGNCTGGLSGYKCLCDAGWV---GINCEVDKNECLSNPCQNGG 770
+C NEC S C++G C + CLC G++ G + +D +EC + G
Sbjct: 527 KNCVDH-NECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNG 585
Query: 771 TCDNLVNGYRCTCKKGFK-GYNCQVNIDECASNPC---LNQGTCFDDISGYT----CHCV 822
C N +RC C G G + +V +D + C + +G+C G C C
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCA 645
Query: 823 LPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP- 881
P G PC P +++A + LC+ G DI+EC P
Sbjct: 646 NPDHGFG-----EPCQLCPAKDSA---------EFQALCSSGLGITTDGRDINECALDPE 691
Query: 882 -CMNHGLCHNTQGSYMCECPPGF----SGMDCEEDIDDCLANP--CQNGGSCMDGVNTFS 934
C N G+C N +GSY C C G+ SG DC D+D+C N C NG C + ++S
Sbjct: 692 VCAN-GVCENLRGSYRCVCNLGYEAGASGKDC-TDVDECALNSLLCDNGW-CQNSPGSYS 748
Query: 935 CLCLPGF---TGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAG------------- 978
C C PGF + D++ECLS PC + G C + SYTCKC G
Sbjct: 749 CSCPPGFHFWQDTEICKDVDECLSSPCVS-GVCRNLAGSYTCKCGPGSRLDPSGTFCLDS 807
Query: 979 --------FDGVHCENNINECT-ESSCFNGGTCVDGINSFSC----LCPVGF---TGSFC 1022
CE N+ + S C G C C GF TG C
Sbjct: 808 TKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTC 867
Query: 1023 LHEINECSSHP--CLNEGTCVDGLGTYRCSCPLGY----TGKNCQTL------------- 1063
++NEC S P C N G CV+ G++RC CP G +G+ C +
Sbjct: 868 -DDVNECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDE 925
Query: 1064 ----------VNLCSRSPCKNKGTCVQ-----KKAESQCLCPSGWAGAYCDVPNVSCDIA 1108
+++C S G + + E LCP G A D +
Sbjct: 926 CGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYK 985
Query: 1109 ASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEE---QLDECASNP--CQHGAT 1163
+ LC H G C N + +C C G+ E +DEC +P C G T
Sbjct: 986 DVNECKVFPGLCTH-GTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG-T 1043
Query: 1164 CSDFIGGYRCECVPGYQG-----VNCEYEVDECQNQPCQ-NGGTCIDLVNHFKCSCPPG- 1216
C + G + CEC PGY+ NC +VDEC P GGTC + +KC CPPG
Sbjct: 1044 CVNTPGSFECECFPGYESGFMLMKNC-MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Query: 1217 ---TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAG----ERCEGDINECL 1269
+G CE+ ID+C+ GQC++ IG + C C GF + C DINEC
Sbjct: 1103 ELTAKGTACED-IDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCV-DINECR 1160
Query: 1270 SNPCSSEGSLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMP-CLNGGTCAVASN 1324
+ + CI Y C C ++ GR C VD C + P + G C +N
Sbjct: 1161 VQ--NGGCDVHCINTEGSYRCSCGQGYSLMPDGRACAD-VDECEENPRVCDQGHC---TN 1214
Query: 1325 MPDGFICRCPPGFSGARCQSSCGQVK--------CRKGEQCVHTASGPRCFCP---SPRD 1373
MP G C C GF +C V C G+ C +T C C R
Sbjct: 1215 MPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGD-CENTKGSFVCHCQLGYMVRK 1273
Query: 1374 CESGCAS-SPCQHGG-SCHPQRQ----PPYYSCQCAPPFSGSRCELYTAPPSTPPATCLS 1427
+GC+ C+ GG +C P +SC+C P + G E + C+S
Sbjct: 1274 GATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLD------ECVS 1327
Query: 1428 QYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV 1487
Q H C GDC + C + DE V
Sbjct: 1328 Q----------------EHRCS-PRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENV 1370
Query: 1488 ECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNS-EECGWDGLDCAADQPENL 1542
+ L DN +C + Y C F + C +EC L CA ENL
Sbjct: 1371 D-LCDNGQCL--NAPGGYRCECEMGFDPTEDHRACQDVDECAQGNL-CAFGSCENL 1422
Score = 292 bits (748), Expect = 2e-78
Identities = 272/882 (30%), Positives = 357/882 (40%), Gaps = 132/882 (14%)
Query: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE----YCQHRDPCEKNRCQNGGTCVAQ 82
+CR+ C + G C+ G+ C C GF C D C++ C NG TC +
Sbjct: 1808 ECREIPNVC-SHGDCMDTE-GSYMCLCHRGFQASADQTLCMDIDECDRQPCGNG-TC--K 1862
Query: 83 AMLGKATCRCASGFT---GEDCQYSTSHPCFVSRPCLNGGTCHMLSR-DTYECTCQVGFT 138
++G C C GF DC V + C G H L+ ++ C CQ GF
Sbjct: 1863 NIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFG---HCLNTAGSFHCLCQDGFE 1919
Query: 139 ----GKECQWTDACLS--HPCANGSTCTTVANQFSCKCLTGFTGQKCET-DVNECDIPGH 191
GK C T+ CLS C G TC + F C C GF Q D++EC +
Sbjct: 1920 LTADGKNCVDTNECLSLAGTCLPG-TCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPN 1978
Query: 192 CQHGGTCLNLPGSYQCQCPQGFT----GQYC-DSLYVPCAPSPCVNGGTCRQTGDFTFE- 245
GTC N PGS+QC CP GF G C D+ C G C F
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTR--FEAGKCSVPKAFNTTK 2036
Query: 246 ----CNCLPGFE-GSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD 300
C+ PG G CE CP Q G + + P EDV+
Sbjct: 2037 TRCCCSKRPGEGWGDPCEL----CP----QEGSAAFQELCPFGHGAVPGPDDS--REDVN 2086
Query: 301 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENI---DDCAFASCTPGSTCIDRV 357
EC P C NG C N +G + C C G+S D N D+C+ TC + +
Sbjct: 2087 ECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVI 2145
Query: 358 ASFSCMCPEG-KAGLL--CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYK----GA 410
F C C +G + GL+ C D C NP C G Y+CTCP GY GA
Sbjct: 2146 GGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNT--EGSYLCTCPAGYTLREDGA 2203
Query: 411 DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY-----AGPRCEMDINECHSDP- 464
C DVDECA + +C N G F C C G +G C D NECH+ P
Sbjct: 2204 MC-RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDD-NECHAQPD 2261
Query: 465 -CQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPC---VNNGQC------VDKVN 514
C N C++ G F C C GF+ E ++ + PC V C + V
Sbjct: 2262 LCVN-GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVT 2320
Query: 515 RFQCLCPPGFT-GPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDN 573
R +C C G GP C++ C K H +GY + ++D
Sbjct: 2321 RAECCCGGGRGWGPRCEL----CPLPGTSAYRKLCPHGSGYTAE----------GRDVDE 2366
Query: 574 CD--PDPCHHGQCQDGIDSYTCICNPGYM----GAICSDQIDECYSSPCLNDGRCIDLVN 627
C C HG+C + + S+ C C GY C D +DEC P C +
Sbjct: 2367 CRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLD-MDECSQVPKPCTFLCKNTKG 2425
Query: 628 GYQCNCQPG----TSGVNCEINFDDCASNPC-IHGICMDGINRYSCVCSPGFTG--QRCN 680
+ C+C G G C+ + D+C S +C++ + ++C C PGFT Q C
Sbjct: 2426 SFLCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQAC- 2483
Query: 681 IDIDECASNP--CRKGATCINGVNGFRCICPEGPHHPSC---YSQVNECLS-NPCIHGNC 734
D DEC++ P C C N FRC C +G S VNEC + C HG C
Sbjct: 2484 FDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG-C 2542
Query: 735 TGGLSGYKCLCDAGWVG----INCEVDKNEC-LSNPCQNGGTCDNLVNGYRCTCKKGFKG 789
L GY+C C G+ C VD+NEC LS P +C N + G+RC C GF
Sbjct: 2543 QNQLGGYRCSCPQGFTQHSQWAQC-VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF 2601
Query: 790 ----YNCQVNIDECAS--NPCLNQGTCFDDISGYTCHCVLPY 825
CQ +DECA PC +C + G+ C C Y
Sbjct: 2602 DQALGGCQ-EVDECAGRRGPC--SYSCANTPGGFLCGCPQGY 2640
Score = 156 bits (394), Expect = 3e-37
Identities = 216/872 (24%), Positives = 309/872 (35%), Gaps = 222/872 (25%)
Query: 802 NPCLNQG--TCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTC 859
+P + QG C Y C + G++ C C A C E + C
Sbjct: 50 SPGILQGPNVCGSRFHAYCCPGWRTFPGRS------QCVVPICRRA--CGEGFCSQPNLC 101
Query: 860 LCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
CA G C + S CMN G C C C G++G C + I D
Sbjct: 102 TCADGTLAPSCGVSRGSGCSVSCMNGGTCRGAS----CLCQKGYTGTVCGQPICD---RG 154
Query: 920 CQNGGSCMDGVNTFSCLCLPGFTGDKCQTD--MNECLSEPCKNGGTCSDYVNSYTC---- 973
C NGG C+ G N C C+ GF G +C+ D C + G C + C
Sbjct: 155 CHNGGRCI-GPN--RCACVYGFMGPQCERDYRTGPCFGQVGPEG--CQHQLTGLVCTKAL 209
Query: 974 ---------------------KCQAGF-DGVH---CENNINEC-TESSCFNGGTCVDGIN 1007
C+ GF +H C+ +++EC GG+CV+ +
Sbjct: 210 CCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQ-DVDECQAVPGLCQGGSCVNMVG 268
Query: 1008 SFSCLCPVGFTGSFCLHEINECSSHPC--LNEGTCVDGLGTYRCSCPLG--YTGKNCQTL 1063
SF C CPVG H +++ SS C G C L RC+ L YT + C
Sbjct: 269 SFHCRCPVG-------HRLSD-SSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQC--- 317
Query: 1064 VNLCSRSPCKNKG----TCVQKKA-ESQCLCPS------GWAGAY--------------- 1097
C R C G C + + E Q LC G G +
Sbjct: 318 --CCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPL 375
Query: 1098 ------------CDVPNV---SCDIAASRRGVLVEHLCQH------SGVCINAGNTHYCQ 1136
+P++ + +I + ++ +C+H +G C+ +++ C+
Sbjct: 376 GPARLNPHGSDARGIPSLGPGNSNIGTATLNQTID-ICRHFTNLCLNGRCLPTPSSYRCE 434
Query: 1137 CPLGYTGSYCEE--QLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE---YEVDEC 1191
C +GYT E +DEC S+PC HG C + G Y C C PG+Q +VDEC
Sbjct: 435 CNVGYTQDVRGECIDVDECTSSPCHHG-DCVNIPGTYHCRCYPGFQATPTRQACVDVDEC 493
Query: 1192 -QNQPCQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGPHCLNGGQCMDRIG 1246
+ + G C++ F+C C G G C ++ ++CA C+N G C++ G
Sbjct: 494 IVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDH-NECATSTMCVN-GVCLNEDG 551
Query: 1247 GYSCRCLPGF----AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT----G 1298
+SC C PGF G C DI+EC + G C + C C G
Sbjct: 552 SFSCLCKPGFLLAPGGHYCM-DIDECQTPGICVNG--HCTNTEGSFRCQCLGGLAVGTDG 608
Query: 1299 RHCETFVDVCPQMPC---LNGGTCA------------VASNMPDGF--ICRCPPGFSGAR 1341
R C VD + C + G+CA +N GF C+ P A
Sbjct: 609 RVC---VDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAE 665
Query: 1342 CQSSCGQ------------------VKCRKGEQCVHTASGPRCFC-------PSPRDC-- 1374
Q+ C C G C + RC C S +DC
Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANG-VCENLRGSYRCVCNLGYEAGASGKDCTD 724
Query: 1375 --ESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCAD 1432
E S C +G Q P YSC C P F + CLS C
Sbjct: 725 VDECALNSLLCDNGWC---QNSPGSYSCSCPPGFHFWQ----DTEICKDVDECLSSPCV- 776
Query: 1433 KARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYI-NNQCD---------- 1481
GVC S+ C+ G L + S+ CW I ++C+
Sbjct: 777 ---SGVCRNLAGSYTCKCGPGS-RLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRS 832
Query: 1482 ELCNTVECLFDNFECQGNSKTCKYDKYCADHF 1513
E C T+ + + C+ C+ D CA F
Sbjct: 833 ECCATLGAAWGS-PCE----RCEIDPACARGF 859
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 496 bits (1276), Expect = e-139
Identities = 259/783 (33%), Positives = 377/783 (48%), Gaps = 82/783 (10%)
Query: 558 CATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCL 617
C G+ G C+E + + H G G C C+ G+ G C DEC P
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPG----ECRCSYGWQGRFC----DECVPYPGC 282
Query: 618 NDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASN-PCIHG-ICMDGI-NRYSCVCSPGF 674
G C++ +QCNC+ G+ C+ + + C S+ PC +G C++ ++Y C C G+
Sbjct: 283 VHGSCVE---PWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY 339
Query: 675 TGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN- 733
+G+ C C SNPC G +C +GF C CP G P+C ++EC SNPC G
Sbjct: 340 SGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGT 399
Query: 734 CTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ 793
C + G++C+C WVG C++D NEC PC N +C NL+ GY C C G+KG NC
Sbjct: 400 CVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCH 459
Query: 794 VNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPN 853
+N+++C C + GTC D ++GY C C + G++C+ C+ +PC + +C++
Sbjct: 460 INVNDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLA- 517
Query: 854 FESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDID 913
+ + C C G+ G C +D+D C PC N C+N +G Y C CP F G +C +
Sbjct: 518 -DGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 576
Query: 914 DCLANPCQ-------NGGSCMDGV-----------------NTFSCLCLPGFTGDKCQTD 949
C C+ + G M G FSC+C GFTG C +
Sbjct: 577 PCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHEN 636
Query: 950 MNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSF 1009
+++CL +PC+NGGTC D V+++ C C +G++G C+ N N+C C + G C D +N F
Sbjct: 637 IDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDF 696
Query: 1010 SCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVN-LCS 1068
C C G+ G C +C ++ C N GTC D T+RC+CP G+ G C N C
Sbjct: 697 YCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCL 756
Query: 1069 RSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCIN 1128
+PC N GTCV A C+C GW G C C+ C + G+C++
Sbjct: 757 PNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLP----------CYNGGICVD 806
Query: 1129 AGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEV 1188
N C+C G+ G C +DEC S+PC +GATC D I GYRC C PG G C+ +
Sbjct: 807 GVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI 866
Query: 1189 D---EC--QNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCAR----GPHCLNGG 1239
C + P +G + ++ N C C G R DC++ CL G
Sbjct: 867 GFGRSCWSRGTPFPHGSSWVEDCN--SCRCLDGRR---------DCSKVWCGWKPCLLAG 915
Query: 1240 QCMDRIGGYSCRCLPGFAGERC-EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG 1298
Q S +C G+RC E +CL PC + G + + C+ RS
Sbjct: 916 Q----PEALSAQCP---LGQRCLEKAPGQCLRPPCEAWGECGAEEPPST-PCLPRSGHLD 967
Query: 1299 RHC 1301
+C
Sbjct: 968 NNC 970
Score = 488 bits (1255), Expect = e-137
Identities = 257/792 (32%), Positives = 380/792 (47%), Gaps = 72/792 (9%)
Query: 315 CANRN---GGYGC------VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF--SCM 363
C RN G Y C C++GW G +C E A C G + + C
Sbjct: 211 CRPRNDFFGHYTCDQYGNKACMDGWMGKECKE-------AVCKQGCNLLHGGCTVPGECR 263
Query: 364 CPEGKAGLLCHLDDACISNP-CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA 422
C G G C D C+ P C G+ + + C C + G C +D++ C
Sbjct: 264 CSYGWQGRFC---DECVPYPGCVHGSCVEP------WQCNCETNWGGLLCDKDLNYCG-- 312
Query: 423 NSNPCEHAGKCVNTD-GAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCL 481
+ +PC + G C+N + + C C GY+G CE + C S+PC N +C + GF C
Sbjct: 313 SHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECH 372
Query: 482 CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC 541
C G+ G C L+I+EC SNPC G CVD+V+ F+C+CP + G CQ+D ++C PC
Sbjct: 373 CPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPC 432
Query: 542 LNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMG 601
LN C + GY C C G+ G+ C N+++C H G C+D ++ Y C+C G+ G
Sbjct: 433 LNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGG 492
Query: 602 AICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CM 660
C + DEC SSPC + G C DL +G+ C+C G SG CE++ D C +PC +G C
Sbjct: 493 RHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCY 552
Query: 661 DGINRYSCVCSPGFTGQRCNIDIDECASNPCR------------KGATCINGVNG----- 703
+ Y C C F G+ C++ + C CR T +GV G
Sbjct: 553 NLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRC 612
Query: 704 -------FRCICPEGPHHPSCYSQVNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCE 755
F CIC G C+ +++CL PC + G C + ++C C +GW G C+
Sbjct: 613 VSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCD 672
Query: 756 VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDIS 815
+ N+CL +PC + G C +LVN + C C G+KG C +C + C N GTC+D
Sbjct: 673 TNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGD 732
Query: 816 GYTCHCVLPYTGKNCQTVL-APCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
+ C C + G C + C PNPC N C S S++C+C GW+G+ CT +
Sbjct: 733 TFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG--ASFSCICRDGWEGRTCTHNT 790
Query: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS 934
++C PC N G+C + + CEC PGF+G DC +ID+C ++PC G +C+D +N +
Sbjct: 791 NDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYR 850
Query: 935 CLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTES 994
C C PG G +CQ + C + GT + +S+ C + C + +C++
Sbjct: 851 CSCPPGRAGPRCQEVIG--FGRSCWSRGTPFPHGSSWVEDC----NSCRCLDGRRDCSKV 904
Query: 995 SCFNGGTCVDG-INSFSCLCPVGFTGSFCLHEI-NECSSHPCLNEGTC-VDGLGTYRCSC 1051
C + G + S CP+ G CL + +C PC G C + + C
Sbjct: 905 WCGWKPCLLAGQPEALSAQCPL---GQRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLP 961
Query: 1052 PLGYTGKNCQTL 1063
G+ NC L
Sbjct: 962 RSGHLDNNCARL 973
Score = 470 bits (1210), Expect = e-132
Identities = 255/768 (33%), Positives = 368/768 (47%), Gaps = 77/768 (10%)
Query: 158 TCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQY 217
TC N+ C+ G+ G++C+ V C + HGG +PG +C+C G+ G++
Sbjct: 222 TCDQYGNK---ACMDGWMGKECKEAV--CKQGCNLLHGGC--TVPG--ECRCSYGWQGRF 272
Query: 218 CDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR-CQNGGVCV 276
CD C P P G+C + ++CNC + G C+++++ C +H C NGG C+
Sbjct: 273 CDE----CVPYPGCVHGSCVEP----WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCI 324
Query: 277 DGV-NTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDC 335
+ + Y C CP ++G+ C + C P C NGG+C G+ C C +GWSG C
Sbjct: 325 NAEPDQYRCTCPDGYSGRNCEKAEHACTSNP--CANGGSCHEVPSGFECHCPSGWSGPTC 382
Query: 336 SENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNP 394
+ +ID+CA C G TC+D+V F C+CPE G C LD + C PC C
Sbjct: 383 ALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKN-- 440
Query: 395 LNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE 454
L G Y C C G+KG +C +V++C C+H G C + + C C +G+ G CE
Sbjct: 441 LIGGYYCDCIPGWKGINCHINVNDC----RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCE 496
Query: 455 MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVN 514
++ +EC S PC + C D GF C C GF G CE++++ C+ +PC N +C +
Sbjct: 497 LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEG 556
Query: 515 RFQCLCPPGFTGPVCQID-----------IDDCSSTP------------CLNGAKCIDHP 551
+ C CP F G C + ID C S C +C+ P
Sbjct: 557 DYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQP 616
Query: 552 NG-YECQCATGFTGVLCEENIDNCDPDPCHH-GQCQDGIDSYTCICNPGYMGAICSDQID 609
G + C C +GFTG C ENID+C PC + G C D +D++ C C G+ G +C +
Sbjct: 617 GGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPN 676
Query: 610 ECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIH-GICMDGINRYSC 668
+C PC + GRC DLVN + C C G G C C + C + G C D + + C
Sbjct: 677 DCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 736
Query: 669 VCSPGFTGQRCNI-DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSN 727
C PG+ G C + C NPC G TC+ F CIC +G +C N+C
Sbjct: 737 ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPL 796
Query: 728 PCIHGN-CTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKG 786
PC +G C G++ ++C C G+ G +C ++ +EC S+PC G TC + +NGYRC+C G
Sbjct: 797 PCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPG 856
Query: 787 FKGYNCQVNIDECASNPCLNQGTCFDDISGY-----TCHCVLPYTGKNCQTVLAPCSPNP 841
G CQ I C ++GT F S + +C C+ ++C V C P
Sbjct: 857 RAGPRCQEVIG--FGRSCWSRGTPFPHGSSWVEDCNSCRCL--DGRRDCSKVW--CGWKP 910
Query: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTIDI-DECISKPCMNHGLC 888
C A P S C GQRC +C+ PC G C
Sbjct: 911 CLLAG----QPEALSAQCPL-----GQRCLEKAPGQCLRPPCEAWGEC 949
Score = 447 bits (1149), Expect = e-125
Identities = 258/790 (32%), Positives = 342/790 (43%), Gaps = 105/790 (13%)
Query: 705 RCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN 764
R C E + +C C G+ T G K D GW+G EC
Sbjct: 195 RVRCDENYYSATCNKF---CRPRNDFFGHYTCDQYGNKACMD-GWMG-------KECKEA 243
Query: 765 PCQNGGTCDNLVNGY----RCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCH 820
C+ G C+ L G C C G++G C DEC P G+C + + C+
Sbjct: 244 VCKQG--CNLLHGGCTVPGECRCSYGWQGRFC----DECVPYPGCVHGSC---VEPWQCN 294
Query: 821 CVLPYTGKNCQTVLAPC-SPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS 879
C + G C L C S +PC N C + + Y C C G+ G+ C C S
Sbjct: 295 CETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEP-DQYRCTCPDGYSGRNCEKAEHACTS 353
Query: 880 KPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLP 939
PC N G CH + C CP G+SG C DID+C +NPC GG+C+D V+ F C+C
Sbjct: 354 NPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPE 413
Query: 940 GFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNG 999
+ G CQ D NEC +PC N +C + + Y C C G+ G++C N+N+C C +G
Sbjct: 414 QWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDC-RGQCQHG 472
Query: 1000 GTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKN 1059
GTC D +N + C+CP GF G C E +EC+S PC + G C D + C CP G++G
Sbjct: 473 GTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPL 532
Query: 1060 CQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR-------- 1111
C+ V+LC SPC+N C + + C CP + G C VP C A R
Sbjct: 533 CEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSD 592
Query: 1112 -----RGVLVEHLCQHSGVCINA-GNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCS 1165
G +C G C++ G C C G+TG+YC E +D+C PC++G TC
Sbjct: 593 AGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCI 652
Query: 1166 DFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEEN 1225
D + +RC C G++G C+ ++C PC + G C DLVN F C+C G +G C
Sbjct: 653 DEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR 712
Query: 1226 IDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINE-CLSNPCSSEGSLDCIQL 1284
C C NGG C D + C C PG+ G C N CL NPC + G+ C+
Sbjct: 713 EFQCDAYT-CSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGT--CVGS 769
Query: 1285 TNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNM-----------PD------ 1327
+ C+CR + GR C + C +PC NGG C N PD
Sbjct: 770 GASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINID 829
Query: 1328 ------------------GFICRCPPGFSGARCQSSCG--------QVKCRKGEQCVHTA 1361
G+ C CPPG +G RCQ G G V
Sbjct: 830 ECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDC 889
Query: 1362 SGPRCFCPSPRDCES-GCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPST 1420
+ RC RDC C PC G QP S QC G RC
Sbjct: 890 NSCRCL-DGRRDCSKVWCGWKPCLLAG------QPEALSAQCP---LGQRC------LEK 933
Query: 1421 PPATCLSQYC 1430
P CL C
Sbjct: 934 APGQCLRPPC 943
Score = 444 bits (1142), Expect = e-124
Identities = 246/752 (32%), Positives = 357/752 (47%), Gaps = 71/752 (9%)
Query: 28 CRDGY------EPCVNEGMCVTYHNGT---GYCKCPEGFLGEYCQHRDPCEKNRCQNGGT 78
C DG+ E +G C H G G C+C G+ G +C + C
Sbjct: 231 CMDGWMGKECKEAVCKQG-CNLLHGGCTVPGECRCSYGWQGRFC--------DECVPYPG 281
Query: 79 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT 138
CV + + C C + + G C ++ C PC NGGTC D Y CTC G++
Sbjct: 282 CVHGSCVEPWQCNCETNWGGLLCDKDLNY-CGSHHPCTNGGTCINAEPDQYRCTCPDGYS 340
Query: 139 GKECQWTD-ACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGT 197
G+ C+ + AC S+PCANG +C V + F C C +G++G C D++EC C GGT
Sbjct: 341 GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDEC-ASNPCAAGGT 399
Query: 198 CLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC 257
C++ ++C CP+ + G C C PC+N +C+ + C+C+PG++G C
Sbjct: 400 CVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIG-GYYCDCIPGWKGINC 458
Query: 258 ERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCAN 317
N++DC +CQ+GG C D VN Y C CP + G+ C + DEC P C +GG C +
Sbjct: 459 HINVNDC-RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSP--CHSGGLCED 515
Query: 318 RNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPE---GK------ 368
G+ C C G+SG C ++D C + C G+ C + + C CP+ GK
Sbjct: 516 LADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPR 575
Query: 369 ---AGLLCHLDDAC------------ISNPCHKGALCDTNPLNGQYICTCPQGYKGADCT 413
G C + D C S C C + P G + C C G+ G C
Sbjct: 576 EPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQP-GGNFSCICDSGFTGTYCH 634
Query: 414 EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLD 473
E++D+C PC + G C++ AF C C G+ G C+ + N+C DPC + C D
Sbjct: 635 ENIDDCL---GQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYD 691
Query: 474 KIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-D 532
+ F C C G+KG C +C + C N G C D + F+C CPPG+ G C +
Sbjct: 692 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 533 IDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQ-CQDGIDSY 591
C PC+NG C+ + C C G+ G C N ++C+P PC++G C DG++ +
Sbjct: 752 NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811
Query: 592 TCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCE--INFD-D 648
C C PG+ G C IDEC SSPC C+D +NGY+C+C PG +G C+ I F
Sbjct: 812 RCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRS 871
Query: 649 CAS--NPCIHGIC-MDGINRYSCV-----CSPGFTGQR-CNI-DIDECASNPCRKGATCI 698
C S P HG ++ N C+ CS + G + C + E S C G C+
Sbjct: 872 CWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCL 931
Query: 699 NGVNGFRCICPEGPHHPSCYSQVNECLSNPCI 730
G +C+ P C ++ E S PC+
Sbjct: 932 EKAPG-QCLRPPCEAWGECGAE--EPPSTPCL 960
Score = 333 bits (855), Expect = 1e-90
Identities = 202/682 (29%), Positives = 298/682 (43%), Gaps = 105/682 (15%)
Query: 893 GSYMCE------CPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTF--SCLCLPGFTGD 944
G Y C+ C G+ G +C+E + C+ G + + G T C C G+ G
Sbjct: 219 GHYTCDQYGNKACMDGWMGKECKEAV-------CKQGCNLLHGGCTVPGECRCSYGWQGR 271
Query: 945 KCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINEC-TESSCFNGGTCV 1003
C +EC+ P G+C V + C C+ + G+ C+ ++N C + C NGGTC+
Sbjct: 272 FC----DECVPYPGCVHGSC---VEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCI 324
Query: 1004 DGI-NSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQT 1062
+ + + C CP G++G C + C+S+PC N G+C + + C CP G++G C
Sbjct: 325 NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCAL 384
Query: 1063 LVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQH 1122
++ C+ +PC GTCV + +C+CP W GA C + C+ C +
Sbjct: 385 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKP----------CLN 434
Query: 1123 SGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGV 1182
+ C N +YC C G+ G C +++C CQHG TC D + GY+C C G+ G
Sbjct: 435 AFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGR 493
Query: 1183 NCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCM 1242
+CE E DEC + PC +GG C DL + F C CP G G LCE ++D C P C NG +C
Sbjct: 494 HCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSP-CRNGARCY 552
Query: 1243 DRIGGYSCRCLPGFAGERCEGDINEC-----------------------LSNPCSSEGSL 1279
+ G Y C C F G+ C C S C G
Sbjct: 553 NLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGR- 611
Query: 1280 DCI-QLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFS 1338
C+ Q ++ C+C S FTG +C +D C PC NGGTC + D F C CP G+
Sbjct: 612 -CVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCI---DEVDAFRCFCPSGWE 667
Query: 1339 GARCQSS---CGQVKCRKGEQCVHTASGPRCFCP---SPRDCES---GCASSPCQHGGSC 1389
G C ++ C C +C + C C + C S C + C +GG+C
Sbjct: 668 GELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTC 727
Query: 1390 HPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHAC- 1448
+ + C C P + GS C + ++CL C + G C + S +C
Sbjct: 728 YDSGDT--FRCACPPGWKGSTCAV------AKNSSCLPNPCVN---GGTCVGSGASFSCI 776
Query: 1449 ---QWDGGDCSLTMENPWANCSSPLPCW---------DYINNQCDELCNTVECLFDNFEC 1496
W+G C+ N +PLPC+ ++ +C +C + EC
Sbjct: 777 CRDGWEGRTCTHN-----TNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDEC 831
Query: 1497 QGNSKTCKYDKYCADHFKDNHC 1518
Q S C Y C D C
Sbjct: 832 Q--SSPCAYGATCVDEINGYRC 851
Score = 135 bits (340), Expect = 5e-31
Identities = 103/356 (28%), Positives = 146/356 (41%), Gaps = 62/356 (17%)
Query: 1160 HGATCS-------DFIGGYRCE------CVPGYQGVNCEYEVDECQNQPCQ--NGGTCID 1204
+ ATC+ DF G Y C+ C+ G+ G C+ V C+ Q C +GG +
Sbjct: 203 YSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAV--CK-QGCNLLHGGCTVP 259
Query: 1205 LVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGD 1264
+C C G +G C D+C P C++G C++ + C C + G C+ D
Sbjct: 260 ----GECRCSYGWQGRFC----DECVPYPGCVHGS-CVEP---WQCNCETNWGGLLCDKD 307
Query: 1265 INECLSN-PCSSEGSLDCIQLTND-YLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVA 1322
+N C S+ PC++ G+ CI D Y C C ++GR+CE C PC NGG+C
Sbjct: 308 LNYCGSHHPCTNGGT--CINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSC--- 362
Query: 1323 SNMPDGFICRCPPGFSGARCQ---SSCGQVKCRKGEQCVHTASGPRCFCPSP---RDCE- 1375
+P GF C CP G+SG C C C G CV G C CP C+
Sbjct: 363 HEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL 422
Query: 1376 --SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADK 1433
+ C PC + SC + Y C C P + G C + C Q
Sbjct: 423 DANECEGKPCLNAFSC--KNLIGGYYCDCIPGWKGINCHINV-------NDCRGQC---- 469
Query: 1434 ARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVEC 1489
G C + N + C G E C+S PC + C++L + C
Sbjct: 470 QHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASS-PC--HSGGLCEDLADGFHC 522
Score = 42.0 bits (97), Expect = 0.007
Identities = 62/274 (22%), Positives = 81/274 (29%), Gaps = 113/274 (41%)
Query: 1277 GSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPG 1336
G C Q N C + G+ C+ V C Q L G C V CRC G
Sbjct: 219 GHYTCDQYGNK---ACMDGWMGKECKEAV--CKQGCNLLHGGCTVPGE------CRCSYG 267
Query: 1337 FSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESG------------CASS-PC 1383
+ G C +C CVH + C P +CE+ C S PC
Sbjct: 268 WQGRFCD------ECVPYPGCVHGS----CVEPWQCNCETNWGGLLCDKDLNYCGSHHPC 317
Query: 1384 QHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEAC 1443
+GG+C +P Y C C +SG CE + AC
Sbjct: 318 TNGGTCI-NAEPDQYRCTCPDGYSGRNCEK-------------------------AEHAC 351
Query: 1444 NSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTC 1503
S+ C +GG C E P FEC
Sbjct: 352 TSNPCA-NGGSCH---EVP-----------------------------SGFEC------- 371
Query: 1504 KYDKYCADHFKDNHCDQGCNSEECGWDGLDCAAD 1537
HC G + C D +CA++
Sbjct: 372 -------------HCPSGWSGPTCALDIDECASN 392
>gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens]
Length = 236
Score = 489 bits (1258), Expect = e-137
Identities = 210/211 (99%), Positives = 210/211 (99%)
Query: 40 MCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGE 99
MCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGE
Sbjct: 1 MCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGE 60
Query: 100 DCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTC 159
DCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTC
Sbjct: 61 DCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTC 120
Query: 160 TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCD 219
TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC QGFTGQYCD
Sbjct: 121 TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCD 180
Query: 220 SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 250
SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP
Sbjct: 181 SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 211
Score = 170 bits (431), Expect = 1e-41
Identities = 84/204 (41%), Positives = 113/204 (55%), Gaps = 8/204 (3%)
Query: 815 SGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
+GY C C + G+ CQ PC N C+N C TC CA G+ G+ C
Sbjct: 9 TGY-CKCPEGFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYST 66
Query: 875 DE--CISKPCMNHGLCHN-TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVN 931
+S+PC+N G CH ++ +Y C C GF+G +C+ D CL++PC NG +C N
Sbjct: 67 SHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVAN 125
Query: 932 TFSCLCLPGFTGDKCQTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINE 990
FSC CL GFTG KC+TD+NEC + C++GGTC + SY C+C GF G +C++
Sbjct: 126 QFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVP 185
Query: 991 CTESSCFNGGTC-VDGINSFSCLC 1013
C S C NGGTC G +F C C
Sbjct: 186 CAPSPCVNGGTCRQTGDFTFECNC 209
Score = 160 bits (406), Expect = 1e-38
Identities = 82/218 (37%), Positives = 113/218 (51%), Gaps = 14/218 (6%)
Query: 1125 VCINAGN-THYCQCPLGYTGSYCEEQLDECASNPCQHGATC--SDFIGGYRCECVPGYQG 1181
+C+ N T YC+CP G+ G YC+ + D C N CQ+G TC +G C C G+ G
Sbjct: 1 MCVTYHNGTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTG 59
Query: 1182 VNCEYEVDE--CQNQPCQNGGTCIDLVNH-FKCSCPPGTRGLLCEENIDDCARGPHCLNG 1238
+C+Y ++PC NGGTC L ++C+C G G C+ D C P C NG
Sbjct: 60 EDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHP-CANG 117
Query: 1239 GQCMDRIGGYSCRCLPGFAGERCEGDINEC-LSNPCSSEGSLDCIQLTNDYLCVCRSAFT 1297
C +SC+CL GF G++CE D+NEC + C G+ C+ L Y C C FT
Sbjct: 118 STCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGT--CLNLPGSYQCQCLQGFT 175
Query: 1298 GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPP 1335
G++C++ C PC+NGGTC + F C C P
Sbjct: 176 GQYCDSLYVPCAPSPCVNGGTCRQTGDFT--FECNCLP 211
Score = 160 bits (406), Expect = 1e-38
Identities = 86/199 (43%), Positives = 112/199 (56%), Gaps = 12/199 (6%)
Query: 889 HNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDG--VNTFSCLCLPGFTGDKC 946
HN G+ C+CP GF G C+ D C N CQNGG+C+ + +C C GFTG+ C
Sbjct: 6 HN--GTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDC 62
Query: 947 Q-TDMNEC-LSEPCKNGGTCSDYV-NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCV 1003
Q + + C +S PC NGGTC ++Y C CQ GF G C+ + C C NG TC
Sbjct: 63 QYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCT 121
Query: 1004 DGINSFSCLCPVGFTGSFCLHEINECS--SHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQ 1061
N FSC C GFTG C ++NEC H C + GTC++ G+Y+C C G+TG+ C
Sbjct: 122 TVANQFSCKCLTGFTGQKCETDVNECDIPGH-CQHGGTCLNLPGSYQCQCLQGFTGQYCD 180
Query: 1062 TLVNLCSRSPCKNKGTCVQ 1080
+L C+ SPC N GTC Q
Sbjct: 181 SLYVPCAPSPCVNGGTCRQ 199
Score = 159 bits (402), Expect = 3e-38
Identities = 86/212 (40%), Positives = 111/212 (52%), Gaps = 10/212 (4%)
Query: 159 CTTVANQFS-CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLN--LPGSYQCQCPQGFTG 215
C T N CKC GF G+ C+ + C+ CQ+GGTC+ + G C+C GFTG
Sbjct: 2 CVTYHNGTGYCKCPEGFLGEYCQHR-DPCE-KNRCQNGGTCVAQAMLGKATCRCASGFTG 59
Query: 216 QYCD-SLYVPCAPS-PCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGG 273
+ C S PC S PC+NGGTC T+EC C GF G C+ D C +H C NG
Sbjct: 60 EDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGS 118
Query: 274 VCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD 333
C N ++C+C +TGQ C DV+EC + P CQ+GGTC N G Y C C+ G++G
Sbjct: 119 TCTTVANQFSCKCLTGFTGQKCETDVNECDI-PGHCQHGGTCLNLPGSYQCQCLQGFTGQ 177
Query: 334 DCSENIDDCAFASCTPGSTCIDR-VASFSCMC 364
C CA + C G TC +F C C
Sbjct: 178 YCDSLYVPCAPSPCVNGGTCRQTGDFTFECNC 209
Score = 147 bits (372), Expect = 1e-34
Identities = 78/209 (37%), Positives = 108/209 (51%), Gaps = 10/209 (4%)
Query: 437 DGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDK--IGGFTCLCMPGFKGVHCELE 494
+G +C+C +G+ G C+ + C + CQN TC+ + +G TC C GF G C+
Sbjct: 7 NGTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYS 65
Query: 495 INE--CQSNPCVNNGQC-VDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP 551
+ S PC+N G C + + ++C C GFTG CQ D C S PC NG+ C
Sbjct: 66 TSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVA 124
Query: 552 NGYECQCATGFTGVLCEENIDNCD-PDPCHH-GQCQDGIDSYTCICNPGYMGAICSDQID 609
N + C+C TGFTG CE +++ CD P C H G C + SY C C G+ G C
Sbjct: 125 NQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV 184
Query: 610 ECYSSPCLNDGRCIDLVN-GYQCNCQPGT 637
C SPC+N G C + ++CNC P T
Sbjct: 185 PCAPSPCVNGGTCRQTGDFTFECNCLPET 213
Score = 147 bits (370), Expect = 2e-34
Identities = 81/220 (36%), Positives = 115/220 (52%), Gaps = 18/220 (8%)
Query: 274 VCVDGVN-TYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRN--GGYGCVCVNGW 330
+CV N T C+CP + G++C + D C + N CQNGGTC + G C C +G+
Sbjct: 1 MCVTYHNGTGYCKCPEGFLGEYC-QHRDPC--EKNRCQNGGTCVAQAMLGKATCRCASGF 57
Query: 331 SGDDCSENIDDCAFAS--CTPGSTC--IDRVASFSCMCPEGKAGLLCHLDDACISNPCHK 386
+G+DC + F S C G TC + R ++ C C G G C DAC+S+PC
Sbjct: 58 TGEDCQYSTSHPCFVSRPCLNGGTCHMLSR-DTYECTCQVGFTGKECQWTDACLSHPCAN 116
Query: 387 GALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLK 446
G+ C T + Q+ C C G+ G C DV+EC + C+H G C+N G++ C+CL+
Sbjct: 117 GSTCTT--VANQFSCKCLTGFTGQKCETDVNECDIPGH--CQHGGTCLNLPGSYQCQCLQ 172
Query: 447 GYAGPRCEMDINECHSDPCQNDATCLDKIGGFT--CLCMP 484
G+ G C+ C PC N TC + G FT C C+P
Sbjct: 173 GFTGQYCDSLYVPCAPSPCVNGGTC-RQTGDFTFECNCLP 211
Score = 143 bits (361), Expect = 2e-33
Identities = 71/203 (34%), Positives = 105/203 (51%), Gaps = 10/203 (4%)
Query: 668 CVCSPGFTGQRCNIDIDECASNPCRKGATCING--VNGFRCICPEGPHHPSC-YSQVNEC 724
C C GF G+ C D C N C+ G TC+ + C C G C YS + C
Sbjct: 12 CKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPC 70
Query: 725 -LSNPCIHGNCTGGLSG--YKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRC 781
+S PC++G LS Y+C C G+ G C+ + CLS+PC NG TC + N + C
Sbjct: 71 FVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSC 129
Query: 782 TCKKGFKGYNCQVNIDEC-ASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN 840
C GF G C+ +++EC C + GTC + Y C C+ +TG+ C ++ PC+P+
Sbjct: 130 KCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPS 189
Query: 841 PCENAAVCKESPNFESYTCLCAP 863
PC N C+++ +F ++ C C P
Sbjct: 190 PCVNGGTCRQTGDF-TFECNCLP 211
Score = 135 bits (341), Expect = 4e-31
Identities = 70/211 (33%), Positives = 98/211 (46%), Gaps = 20/211 (9%)
Query: 1087 CLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG--NTHYCQCPLGYTGS 1144
C CP G+ G YC R ++ CQ+ G C+ C+C G+TG
Sbjct: 12 CKCPEGFLGEYCQ-----------HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGE 60
Query: 1145 YCEEQLDE--CASNPCQHGATCSDFI-GGYRCECVPGYQGVNCEYEVDECQNQPCQNGGT 1201
C+ S PC +G TC Y C C G+ G C++ D C + PC NG T
Sbjct: 61 DCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW-TDACLSHPCANGST 119
Query: 1202 CIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
C + N F C C G G CE ++++C HC +GG C++ G Y C+CL GF G+ C
Sbjct: 120 CTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYC 179
Query: 1262 EGDINECLSNPCSSEGSLDCIQLTNDYLCVC 1292
+ C +PC + G+ C Q T D+ C
Sbjct: 180 DSLYVPCAPSPCVNGGT--CRQ-TGDFTFEC 207
Score = 134 bits (338), Expect = 8e-31
Identities = 76/210 (36%), Positives = 100/210 (47%), Gaps = 19/210 (9%)
Query: 935 CLCLPGFTGDKCQTDMNECLSEPCKNGGTC--SDYVNSYTCKCQAGFDGVHCENNINE-C 991
C C GF G+ CQ + C C+NGGTC + TC+C +GF G C+ + + C
Sbjct: 12 CKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPC 70
Query: 992 TESS-CFNGGTC-VDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRC 1049
S C NGGTC + +++ C C VGFTG C + C SHPC N TC + C
Sbjct: 71 FVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACLSHPCANGSTCTTVANQFSC 129
Query: 1050 SCPLGYTGKNCQTLVNLCS-RSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIA 1108
C G+TG+ C+T VN C C++ GTC+ QC C G+ G YCD V C
Sbjct: 130 KCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPC--- 186
Query: 1109 ASRRGVLVEHLCQHSGVCINAGN-THYCQC 1137
C + G C G+ T C C
Sbjct: 187 -------APSPCVNGGTCRQTGDFTFECNC 209
Score = 128 bits (321), Expect = 8e-29
Identities = 77/216 (35%), Positives = 106/216 (49%), Gaps = 15/216 (6%)
Query: 622 CIDLVNGY-QCNCQPGTSGVNCEINFDDCASNPCIHG---ICMDGINRYSCVCSPGFTGQ 677
C+ NG C C G G C+ + D C N C +G + + + +C C+ GFTG+
Sbjct: 2 CVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGE 60
Query: 678 RCNIDIDE--CASNPCRKGATC-INGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN- 733
C S PC G TC + + + C C G C + CLS+PC +G+
Sbjct: 61 DCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACLSHPCANGST 119
Query: 734 CTGGLSGYKCLCDAGWVGINCEVDKNEC-LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNC 792
CT + + C C G+ G CE D NEC + CQ+GGTC NL Y+C C +GF G C
Sbjct: 120 CTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYC 179
Query: 793 QVNIDECASNPCLNQGTC--FDDISGYTCHCVLPYT 826
CA +PC+N GTC D + + C+C LP T
Sbjct: 180 DSLYVPCAPSPCVNGGTCRQTGDFT-FECNC-LPET 213
Score = 125 bits (314), Expect = 5e-28
Identities = 71/202 (35%), Positives = 98/202 (48%), Gaps = 11/202 (5%)
Query: 480 CLCMPGFKGVHCELEINECQSNPCVNNGQCVDK--VNRFQCLCPPGFTGPVCQIDIDDCS 537
C C GF G +C+ + C+ N C N G CV + + + C C GFTG CQ
Sbjct: 12 CKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPC 70
Query: 538 --STPCLNGAKC-IDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQ-CQDGIDSYTC 593
S PCLNG C + + YEC C GFTG C+ D C PC +G C + ++C
Sbjct: 71 FVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSC 129
Query: 594 ICNPGYMGAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASN 652
C G+ G C ++EC C + G C++L YQC C G +G C+ + CA +
Sbjct: 130 KCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPS 189
Query: 653 PCIH-GIC-MDGINRYSCVCSP 672
PC++ G C G + C C P
Sbjct: 190 PCVNGGTCRQTGDFTFECNCLP 211
Score = 121 bits (303), Expect = 1e-26
Identities = 71/209 (33%), Positives = 104/209 (49%), Gaps = 24/209 (11%)
Query: 1211 CSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDR--IGGYSCRCLPGFAGERCEGDINE- 1267
C CP G G C+ D C + C NGG C+ + +G +CRC GF GE C+ +
Sbjct: 12 CKCPEGFLGEYCQHR-DPCEKN-RCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 1268 -CLSNPCSSEGSLDCIQLTND-YLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNM 1325
+S PC + G+ C L+ D Y C C+ FTG+ C+ + D C PC NG TC +N
Sbjct: 70 CFVSRPCLNGGT--CHMLSRDTYECTCQVGFTGKECQ-WTDACLSHPCANGSTCTTVANQ 126
Query: 1326 PDGFICRCPPGFSGARCQSSCGQVK----CRKGEQCVHTASGPRCFCP---SPRDCES-- 1376
F C+C GF+G +C++ + C+ G C++ +C C + + C+S
Sbjct: 127 ---FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLY 183
Query: 1377 -GCASSPCQHGGSCHPQRQPPYYSCQCAP 1404
CA SPC +GG+C Q + C C P
Sbjct: 184 VPCAPSPCVNGGTCR-QTGDFTFECNCLP 211
Score = 106 bits (264), Expect = 3e-22
Identities = 54/140 (38%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Query: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCA 93
PC+N G C T C C GF G+ CQ D C + C NG TC A + +C+C
Sbjct: 75 PCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVA--NQFSCKCL 132
Query: 94 SGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA-CLSHP 152
+GFTG+ C+ + C + C +GGTC L +Y+C C GFTG+ C C P
Sbjct: 133 TGFTGQKCETDVNE-CDIPGHCQHGGTCLNLP-GSYQCQCLQGFTGQYCDSLYVPCAPSP 190
Query: 153 CANGSTCTTVAN-QFSCKCL 171
C NG TC + F C CL
Sbjct: 191 CVNGGTCRQTGDFTFECNCL 210
Score = 72.4 bits (176), Expect = 5e-12
Identities = 59/196 (30%), Positives = 80/196 (40%), Gaps = 29/196 (14%)
Query: 1290 CVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQV 1349
C C F G +C+ D C + C NGGTC VA M CRC GF+G CQ S
Sbjct: 12 CKCPEGFLGEYCQ-HRDPCEKNRCQNGGTC-VAQAMLGKATCRCASGFTGEDCQYSTSHP 69
Query: 1350 -----KCRKGEQCVHTASGP--RCFCP---SPRDCE--SGCASSPCQHGGSCHPQRQPPY 1397
C G C H S C C + ++C+ C S PC +G +C
Sbjct: 70 CFVSRPCLNGGTC-HMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN--Q 126
Query: 1398 YSCQCAPPFSGSRCELYTAPPSTPPATC-LSQYCADKARDGVCDEACNSHACQWDGGDCS 1456
+SC+C F+G +CE T C + +C G C S+ CQ G
Sbjct: 127 FSCKCLTGFTGQKCE-------TDVNECDIPGHC---QHGGTCLNLPGSYQCQCLQGFTG 176
Query: 1457 LTMENPWANCSSPLPC 1472
++ + C +P PC
Sbjct: 177 QYCDSLYVPC-APSPC 191
Score = 52.8 bits (125), Expect = 4e-06
Identities = 48/203 (23%), Positives = 68/203 (33%), Gaps = 48/203 (23%)
Query: 1331 CRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCH 1390
C+CP GF G CQ C + CQ+GG+C
Sbjct: 12 CKCPEGFLGEYCQH------------------------------RDPCEKNRCQNGGTCV 41
Query: 1391 PQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLS-QYCADKARDG---VCDEACNSH 1446
Q +C+CA F+G C+ T+ P CL+ C +RD C
Sbjct: 42 AQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGK 101
Query: 1447 ACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQ-----GNSK 1501
CQW + +P AN S+ + + +C +C D EC +
Sbjct: 102 ECQW----TDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGG 157
Query: 1502 TC-----KYDKYCADHFKDNHCD 1519
TC Y C F +CD
Sbjct: 158 TCLNLPGSYQCQCLQGFTGQYCD 180
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 460 bits (1183), Expect = e-129
Identities = 252/761 (33%), Positives = 365/761 (47%), Gaps = 89/761 (11%)
Query: 586 DGIDSYTC------ICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSG 639
D YTC C G+MG C + + C L G C V G +C C G G
Sbjct: 216 DFFGHYTCDQYGNKACMDGWMGKECKEAV--CKQGCNLLHGGCT--VPG-ECRCSYGWQG 270
Query: 640 VNCEINFDDCASNP-CIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASN-PCRKGATC 697
C D+C P C+HG C++ + C C + G C+ D++ C S+ PC G TC
Sbjct: 271 RFC----DECVPYPGCVHGSCVEP---WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTC 323
Query: 698 INGV-NGFRCICPEGPHHPSCYSQVNECLSNPCIHG-NCTGGLSGYKCLCDAGWVGINCE 755
IN + +RC CP+G +C + C SNPC +G +C SG++C C +GW G C
Sbjct: 324 INAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCA 383
Query: 756 VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDIS 815
+D +EC SNPC GGTC + V+G+ C C + + G CQ+++++C C + GTC D ++
Sbjct: 384 LDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ-CQHGGTCKDLVN 442
Query: 816 GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDID 875
GY C C + G++C+ C+ +PC + +C++ + + C C G+ G C +D+D
Sbjct: 443 GYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLA--DGFHCHCPQGFSGPLCEVDVD 500
Query: 876 ECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQ-------NGGSCMD 928
C PC N C+N +G Y C CP F G +C + C C+ + G M
Sbjct: 501 LCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMP 560
Query: 929 GV-----------------NTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSY 971
G FSC+C GFTG C ++++CL +PC+NGGTC D V+++
Sbjct: 561 GTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAF 620
Query: 972 TCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSS 1031
C C +G++G C+ N N+C C + G C D +N F C C G+ G C +C +
Sbjct: 621 RCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA 680
Query: 1032 HPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVN-LCSRSPCKNKGTCVQKKAESQCLCP 1090
+ C N GTC D T+RC+CP G+ G C N C +PC N GTCV A C+C
Sbjct: 681 YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICR 740
Query: 1091 SGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQL 1150
GW G C C+ C + G+C++ N C+C G+ G C +
Sbjct: 741 DGWEGRTCTHNTNDCNPLP----------CYNGGICVDGVNWFRCECAPGFAGPDCRINI 790
Query: 1151 DECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVD---EC--QNQPCQNGGTCIDL 1205
DEC S+PC +GATC D I GYRC C PG G C+ + C + P +G + ++
Sbjct: 791 DECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVED 850
Query: 1206 VNHFKCSCPPGTRGLLCEENIDDCAR----GPHCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
N C C G R DC++ CL GQ S +C G+RC
Sbjct: 851 CN--SCRCLDGRR---------DCSKVWCGWKPCLLAGQ----PEALSAQCP---LGQRC 892
Query: 1262 -EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC 1301
E +CL PC + G + + C+ RS +C
Sbjct: 893 LEKAPGQCLRPPCEAWGECGAEEPPST-PCLPRSGHLDNNC 932
Score = 448 bits (1152), Expect = e-125
Identities = 248/790 (31%), Positives = 366/790 (46%), Gaps = 106/790 (13%)
Query: 315 CANRN---GGYGC------VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCP 365
C RN G Y C C++GW G +C E + C
Sbjct: 211 CRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAV------------------------CK 246
Query: 366 EGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSN 425
+G C+L H G C C G++G C DEC
Sbjct: 247 QG-----CNL--------LHGGCTVPGE-------CRCSYGWQGRFC----DECVPYPG- 281
Query: 426 PCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSD-PCQNDATCLD-KIGGFTCLCM 483
C H G CV + C C + G C+ D+N C S PC N TC++ + + C C
Sbjct: 282 -CVH-GSCVEP---WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCP 336
Query: 484 PGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLN 543
G+ G +CE + C SNPC N G C + + F+C CP G++GP C +DID+C+S PC
Sbjct: 337 DGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAA 396
Query: 544 GAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAI 603
G C+D +G+EC C + G C+ ++++C H G C+D ++ Y C+C G+ G
Sbjct: 397 GGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRH 456
Query: 604 CSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDG 662
C + DEC SSPC + G C DL +G+ C+C G SG CE++ D C +PC +G C +
Sbjct: 457 CELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNL 516
Query: 663 INRYSCVCSPGFTGQRCNIDIDECASNPCR------------KGATCINGVNG------- 703
Y C C F G+ C++ + C CR T +GV G
Sbjct: 517 EGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVS 576
Query: 704 -----FRCICPEGPHHPSCYSQVNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVD 757
F CIC G C+ +++CL PC + G C + ++C C +GW G C+ +
Sbjct: 577 QPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTN 636
Query: 758 KNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGY 817
N+CL +PC + G C +LVN + C C G+KG C +C + C N GTC+D +
Sbjct: 637 PNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTF 696
Query: 818 TCHCVLPYTGKNCQTVL-APCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDE 876
C C + G C + C PNPC N C S S++C+C GW+G+ CT + ++
Sbjct: 697 RCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG--ASFSCICRDGWEGRTCTHNTND 754
Query: 877 CISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
C PC N G+C + + CEC PGF+G DC +ID+C ++PC G +C+D +N + C
Sbjct: 755 CNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCS 814
Query: 937 CLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSC 996
C PG G +CQ + C + GT + +S+ C + C + +C++ C
Sbjct: 815 CPPGRAGPRCQEVIG--FGRSCWSRGTPFPHGSSWVEDC----NSCRCLDGRRDCSKVWC 868
Query: 997 FNGGTCVDG-INSFSCLCPVGFTGSFCLHEI-NECSSHPCLNEGTC-VDGLGTYRCSCPL 1053
+ G + S CP+ G CL + +C PC G C + + C
Sbjct: 869 GWKPCLLAGQPEALSAQCPL---GQRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPRS 925
Query: 1054 GYTGKNCQTL 1063
G+ NC L
Sbjct: 926 GHLDNNCARL 935
Score = 448 bits (1152), Expect = e-125
Identities = 249/755 (32%), Positives = 358/755 (47%), Gaps = 86/755 (11%)
Query: 158 TCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQY 217
TC N+ C+ G+ G++C+ V C + HGG +PG +C+C G+ G++
Sbjct: 222 TCDQYGNK---ACMDGWMGKECKEAV--CKQGCNLLHGGC--TVPG--ECRCSYGWQGRF 272
Query: 218 CDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR-CQNGGVCV 276
CD C P P G+C + ++CNC + G C+++++ C +H C NGG C+
Sbjct: 273 CDE----CVPYPGCVHGSCVEP----WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCI 324
Query: 277 DGV-NTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDC 335
+ + Y C CP ++G+ C + C P C NGG+C G+ C C +GWSG C
Sbjct: 325 NAEPDQYRCTCPDGYSGRNCEKAEHACTSNP--CANGGSCHEVPSGFECHCPSGWSGPTC 382
Query: 336 SENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPL 395
+ +ID+CA C G TC+D+V F C+CPE G C LD C G C + +
Sbjct: 383 ALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTC-KDLV 441
Query: 396 NGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEM 455
NG Y C CP+G+ G C + DECA S+PC G C + FHC C +G++GP CE+
Sbjct: 442 NG-YQCVCPRGFGGRHCELERDECA---SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV 497
Query: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINEC----------------- 498
D++ C PC+N A C + G + C C F G +C + C
Sbjct: 498 DVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGP 557
Query: 499 ------QSNPCVNNGQCVDKV-NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP 551
S C +G+CV + F C+C GFTG C +IDDC PC NG CID
Sbjct: 558 GMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEV 617
Query: 552 NGYECQCATGFTGVLCEENIDNCDPDPCH-HGQCQDGIDSYTCICNPGYMGAICSDQIDE 610
+ + C C +G+ G LC+ N ++C PDPCH G+C D ++ + C C+ G+ G C + +
Sbjct: 618 DAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ 677
Query: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEI-NFDDCASNPCIH-GICMDGINRYSC 668
C + C N G C D + ++C C PG G C + C NPC++ G C+ +SC
Sbjct: 678 CDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSC 737
Query: 669 VCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNP 728
+C G+ G+ C + ++C PC G C++GVN FRC C G P C ++EC S+P
Sbjct: 738 ICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSP 797
Query: 729 CIHG-NCTGGLSGYKCLCDAGWVGINCEV---DKNECLS--NPCQNGGTCDNLVNGYRC- 781
C +G C ++GY+C C G G C+ C S P +G + N RC
Sbjct: 798 CAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCL 857
Query: 782 ----TCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC-QTVLAP 836
C K + C PCL G + C L G+ C +
Sbjct: 858 DGRRDCSKVW-----------CGWKPCLLAG----QPEALSAQCPL---GQRCLEKAPGQ 899
Query: 837 CSPNPCENAAVC-KESPNFESYTCLCAPGWQGQRC 870
C PCE C E P S CL G C
Sbjct: 900 CLRPPCEAWGECGAEEP--PSTPCLPRSGHLDNNC 932
Score = 409 bits (1050), Expect = e-113
Identities = 238/721 (33%), Positives = 313/721 (43%), Gaps = 98/721 (13%)
Query: 771 TCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
TCD N C G+ G C+ + C L G C + G C C + G+ C
Sbjct: 222 TCDQYGNK---ACMDGWMGKECKEAV--CKQGCNLLHGGC--TVPG-ECRCSYGWQGRFC 273
Query: 831 QTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK-PCMNHGLCH 889
C P P C E + C C W G C D++ C S PC N G C
Sbjct: 274 DE----CVPYPG-----CVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCI 324
Query: 890 NTQ-GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT 948
N + Y C CP G+SG +CE+ C +NPC NGGSC + + F C C G++G C
Sbjct: 325 NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCAL 384
Query: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINS 1008
D++EC S PC GGTC D V+ + C C + G C+ ++N+C C +GGTC D +N
Sbjct: 385 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDC-RGQCQHGGTCKDLVNG 443
Query: 1009 FSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCS 1068
+ C+CP GF G C E +EC+S PC + G C D + C CP G++G C+ V+LC
Sbjct: 444 YQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCE 503
Query: 1069 RSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASR-------------RGVL 1115
SPC+N C + + C CP + G C VP C A R G
Sbjct: 504 PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTA 563
Query: 1116 VEHLCQHSGVCINA-GNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCE 1174
+C G C++ G C C G+TG+YC E +D+C PC++G TC D + +RC
Sbjct: 564 ASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCF 623
Query: 1175 CVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPH 1234
C G++G C+ ++C PC + G C DLVN F C+C G +G C C
Sbjct: 624 CPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYT- 682
Query: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINE-CLSNPCSSEGSLDCIQLTNDYLCVCR 1293
C NGG C D + C C PG+ G C N CL NPC + G+ C+ + C+CR
Sbjct: 683 CSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGT--CVGSGASFSCICR 740
Query: 1294 SAFTGRHCETFVDVCPQMPCLNGGTCAVASNM-----------PD--------------- 1327
+ GR C + C +PC NGG C N PD
Sbjct: 741 DGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAY 800
Query: 1328 ---------GFICRCPPGFSGARCQSSCG--------QVKCRKGEQCVHTASGPRCFCPS 1370
G+ C CPPG +G RCQ G G V + RC
Sbjct: 801 GATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCL-DG 859
Query: 1371 PRDCES-GCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQY 1429
RDC C PC G QP S QC G RC P CL
Sbjct: 860 RRDCSKVWCGWKPCLLAG------QPEALSAQCP---LGQRC------LEKAPGQCLRPP 904
Query: 1430 C 1430
C
Sbjct: 905 C 905
Score = 409 bits (1050), Expect = e-113
Identities = 236/714 (33%), Positives = 325/714 (45%), Gaps = 108/714 (15%)
Query: 28 CRDGY------EPCVNEGMCVTYHNGT---GYCKCPEGFLGEYCQHRDPCEKNRCQNGGT 78
C DG+ E +G C H G G C+C G+ G +C + C
Sbjct: 231 CMDGWMGKECKEAVCKQG-CNLLHGGCTVPGECRCSYGWQGRFC--------DECVPYPG 281
Query: 79 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT 138
CV + + C C + + G C ++ C PC NGGTC D Y CTC G++
Sbjct: 282 CVHGSCVEPWQCNCETNWGGLLCDKDLNY-CGSHHPCTNGGTCINAEPDQYRCTCPDGYS 340
Query: 139 GKECQWTD-ACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNEC----------- 186
G+ C+ + AC S+PCANG +C V + F C C +G++G C D++EC
Sbjct: 341 GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTC 400
Query: 187 -------------------------DIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSL 221
D G CQHGGTC +L YQC CP+GF G++C+
Sbjct: 401 VDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELE 460
Query: 222 YVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNT 281
CA SPC +GG C D F C+C GF G CE ++D C C+NG C +
Sbjct: 461 RDECASSPCHSGGLCEDLAD-GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGD 519
Query: 282 YNCRCPPQWTGQFCTEDVDEC---------------------LLQPNACQNGGTCANRNG 320
Y C CP + G+ C+ + C C G C ++ G
Sbjct: 520 YYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPG 579
Query: 321 G-YGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DA 378
G + C+C +G++G C ENIDDC C G TCID V +F C CP G G LC + +
Sbjct: 580 GNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPND 639
Query: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438
C+ +PCH C L + C C G+KG C +C ++ C + G C ++
Sbjct: 640 CLPDPCHSRGRC--YDLVNDFYCACDDGWKGKTCHSREFQC---DAYTCSNGGTCYDSGD 694
Query: 439 AFHCECLKGYAGPRCEMDIN-ECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINE 497
F C C G+ G C + N C +PC N TC+ F+C+C G++G C N+
Sbjct: 695 TFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTND 754
Query: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQ 557
C PC N G CVD VN F+C C PGF GP C+I+ID+C S+PC GA C+D NGY C
Sbjct: 755 CNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCS 814
Query: 558 CATGFTGVLCEENID---NC----DPDP--------CHHGQCQDG-IDSYTCICNPGYMG 601
C G G C+E I +C P P C+ +C DG D C G+
Sbjct: 815 CPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWC--GWKP 872
Query: 602 AICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCI 655
+ + Q E S+ C RC++ G QC P + C ++ S PC+
Sbjct: 873 CLLAGQ-PEALSAQCPLGQRCLEKAPG-QCLRPPCEAWGEC--GAEEPPSTPCL 922
Score = 310 bits (794), Expect = 1e-83
Identities = 191/634 (30%), Positives = 274/634 (43%), Gaps = 103/634 (16%)
Query: 937 CLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT----CKCQAGFDGVHCENNINECT 992
C+ G+ G EC CK G C+ T C+C G+ G C+ EC
Sbjct: 231 CMDGWMG-------KECKEAVCKQG--CNLLHGGCTVPGECRCSYGWQGRFCD----ECV 277
Query: 993 ESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH-PCLNEGTCVDGL-GTYRCS 1050
G+CV+ + C C + G C ++N C SH PC N GTC++ YRC+
Sbjct: 278 PYPGCVHGSCVE---PWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCT 334
Query: 1051 CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAAS 1110
CP GY+G+NC+ + C+ +PC N G+C + + +C CPSGW+G C + C
Sbjct: 335 CPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDEC----- 389
Query: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGG 1170
+ C G C++ + C CP + G+ C+ +++C CQHG TC D + G
Sbjct: 390 -----ASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ-CQHGGTCKDLVNG 443
Query: 1171 YRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCA 1230
Y+C C G+ G +CE E DEC + PC +GG C DL + F C CP G G LCE ++D C
Sbjct: 444 YQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCE 503
Query: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINEC---------------------- 1268
P C NG +C + G Y C C F G+ C C
Sbjct: 504 PSP-CRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGT 562
Query: 1269 -LSNPCSSEGSLDCI-QLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMP 1326
S C G C+ Q ++ C+C S FTG +C +D C PC NGGTC +
Sbjct: 563 AASGVCGPHGR--CVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCI---DEV 617
Query: 1327 DGFICRCPPGFSGARCQSS---CGQVKCRKGEQCVHTASGPRCFCP---SPRDCES---G 1377
D F C CP G+ G C ++ C C +C + C C + C S
Sbjct: 618 DAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ 677
Query: 1378 CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDG 1437
C + C +GG+C+ + C C P + GS C + ++CL C + G
Sbjct: 678 CDAYTCSNGGTCYDSGDT--FRCACPPGWKGSTCAV------AKNSSCLPNPCVN---GG 726
Query: 1438 VCDEACNSHAC----QWDGGDCSLTMENPWANCSSPLPCW---------DYINNQCDELC 1484
C + S +C W+G C+ N +PLPC+ ++ +C
Sbjct: 727 TCVGSGASFSCICRDGWEGRTCTHN-----TNDCNPLPCYNGGICVDGVNWFRCECAPGF 781
Query: 1485 NTVECLFDNFECQGNSKTCKYDKYCADHFKDNHC 1518
+C + ECQ S C Y C D C
Sbjct: 782 AGPDCRINIDECQ--SSPCAYGATCVDEINGYRC 813
Score = 139 bits (350), Expect = 3e-32
Identities = 103/340 (30%), Positives = 141/340 (41%), Gaps = 62/340 (18%)
Query: 1160 HGATCS-------DFIGGYRCE------CVPGYQGVNCEYEVDECQNQPCQ--NGGTCID 1204
+ ATC+ DF G Y C+ C+ G+ G C+ V C+ Q C +GG +
Sbjct: 203 YSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAV--CK-QGCNLLHGGCTVP 259
Query: 1205 LVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGD 1264
+C C G +G C D+C P C++G C++ + C C + G C+ D
Sbjct: 260 ----GECRCSYGWQGRFC----DECVPYPGCVHGS-CVEP---WQCNCETNWGGLLCDKD 307
Query: 1265 INECLSN-PCSSEGSLDCIQLTND-YLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVA 1322
+N C S+ PC++ G+ CI D Y C C ++GR+CE C PC NGG+C
Sbjct: 308 LNYCGSHHPCTNGGT--CINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSC--- 362
Query: 1323 SNMPDGFICRCPPGFSGARCQ---SSCGQVKCRKGEQCVHTASGPRCFCPSP-------- 1371
+P GF C CP G+SG C C C G CV G C CP
Sbjct: 363 HEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL 422
Query: 1372 --RDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQY 1429
DC CQHGG+C Y C C F G CEL ++ P C S
Sbjct: 423 DVNDCR-----GQCQHGGTCKDLVNG--YQCVCPRGFGGRHCELERDECASSP--CHSGG 473
Query: 1430 CADKARDGV---CDEACNSHACQWDGGDCSLTMENPWANC 1466
+ DG C + + C+ D C + A C
Sbjct: 474 LCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARC 513
Score = 42.0 bits (97), Expect = 0.007
Identities = 62/274 (22%), Positives = 81/274 (29%), Gaps = 113/274 (41%)
Query: 1277 GSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPG 1336
G C Q N C + G+ C+ V C Q L G C V CRC G
Sbjct: 219 GHYTCDQYGNK---ACMDGWMGKECKEAV--CKQGCNLLHGGCTVPGE------CRCSYG 267
Query: 1337 FSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESG------------CASS-PC 1383
+ G C +C CVH + C P +CE+ C S PC
Sbjct: 268 WQGRFCD------ECVPYPGCVHGS----CVEPWQCNCETNWGGLLCDKDLNYCGSHHPC 317
Query: 1384 QHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEAC 1443
+GG+C +P Y C C +SG CE + AC
Sbjct: 318 TNGGTCI-NAEPDQYRCTCPDGYSGRNCEK-------------------------AEHAC 351
Query: 1444 NSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTC 1503
S+ C +GG C E P FEC
Sbjct: 352 TSNPCA-NGGSCH---EVP-----------------------------SGFEC------- 371
Query: 1504 KYDKYCADHFKDNHCDQGCNSEECGWDGLDCAAD 1537
HC G + C D +CA++
Sbjct: 372 -------------HCPSGWSGPTCALDIDECASN 392
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 455 bits (1170), Expect = e-127
Identities = 242/678 (35%), Positives = 329/678 (48%), Gaps = 77/678 (11%)
Query: 717 CYSQVNECLS-NPCIHG-----NCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGG 770
C + CL+ PC++G +C G Y C C +G+ G C +D NEC S PCQNGG
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 771 TCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
TC + +N +RC C GF G C+ C + C + G C + C C YTG C
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 831 QTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTID----IDECISKPCMNHG 886
+ + CSP+PC N C + +YTCLCA ++G RC D C+S PC N G
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVG--NYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG 442
Query: 887 LCHNTQGSYMCECPPGFSGMDCEEDI-DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDK 945
C + Y+CECP GF G+DC E + DDC C+NGG C+ G NT C C GF G
Sbjct: 443 TCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCL-GANTTLCQCPLGFFGLL 498
Query: 946 CQ--------------------------------TDMN-------ECLSEPCKNGGTCSD 966
C+ TD N C S+PC NGG+C
Sbjct: 499 CEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDA 558
Query: 967 YVNSYTCKCQAGFDGVHCEN-NINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC-LH 1024
+ +SYTC+C GF G HCE + C+ C NGGTC + + C CP FTG C +
Sbjct: 559 HDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIG 618
Query: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAE 1084
+ + C+S PC N GTC +G Y+C CP G++G++C+ + C RSPC N GTC + +
Sbjct: 619 KPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTD 678
Query: 1085 SQCLCPSGWAGAYC----------DVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY 1134
C C +G+ G C +V + + +R G + + C
Sbjct: 679 FFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRV 738
Query: 1135 CQCPLGYTGS--YCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQ 1192
CQ P G C E +DEC S PC HG +C D + GY C C GY+G +CE E DEC+
Sbjct: 739 CQ-PHGVWSEPPQCLE-IDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECR 796
Query: 1193 NQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRC 1252
PC+NGG+C +L + C CP G G+ CE +D C P C +GG+C G Y C C
Sbjct: 797 AHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSP-CQHGGRCESGGGAYLCVC 855
Query: 1253 LPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC--ETFVDVCPQ 1310
F G CE + C S+PC G C+ + C C+ +TG C E F +
Sbjct: 856 PESFFGYHCETVSDPCFSSPCGGRGY--CLASNGSHSCTCKVGYTGEDCAKELFPPTALK 913
Query: 1311 MPCLNGGTCAVASNMPDG 1328
M + +++ N P+G
Sbjct: 914 MERVEESGVSISWNPPNG 931
Score = 431 bits (1109), Expect = e-120
Identities = 225/646 (34%), Positives = 322/646 (49%), Gaps = 52/646 (8%)
Query: 229 PCVNGGTCRQ---TGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCR 285
PC+NGG C TG+ ++ C+CL GF G C ++++C + CQNGG C G+N++ C+
Sbjct: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
Query: 286 CPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFA 345
CP + G C C CQ+GG C NG CVC G++G C ++DDC+
Sbjct: 337 CPAGFGGPTCETAQSPC--DTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPD 394
Query: 346 SCTPGSTCIDRVASFSCMCPEGKAGLLCH-----LDDACISNPCHKGALCDTNPLNGQYI 400
C G +C+D V +++C+C E GL C + DAC+S PCH G C + Y+
Sbjct: 395 PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVD--ADQGYV 452
Query: 401 CTCPQGYKGADCTEDV-DECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINE 459
C CP+G+ G DC E V D+C C + G+C+ + C+C G+ G CE +I
Sbjct: 453 CECPEGFMGLDCRERVPDDCE------CRNGGRCLGANTTL-CQCPLGFFGLLCEFEITA 505
Query: 460 --CHSDP-CQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRF 516
C+ + C + C++ G + C+C H + C S+PC N G C + +
Sbjct: 506 MPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLP--SPCDSDPCFNGGSCDAHDDSY 563
Query: 517 QCLCPPGFTGPVCQIDIDD-CSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE-ENIDNC 574
C CP GF G C+ CSS PC NG C + Y C C FTG CE D+C
Sbjct: 564 TCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSC 623
Query: 575 DPDPCHHG-QCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNC 633
PCH+G C I Y C C PG+ G C C+ SPC+N G C D + C+C
Sbjct: 624 ASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHC 683
Query: 634 QPGTSGVNCEINFDDCASNPCIH------GICMDGINRYSC-------------VCSP-G 673
Q G G C+ D H G + + Y+C VC P G
Sbjct: 684 QAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHG 743
Query: 674 FTGQ--RCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIH 731
+ +C ++IDEC S PC G +C + V G+ C+C G C + +EC ++PC +
Sbjct: 744 VWSEPPQC-LEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRN 802
Query: 732 GNCTGGLSG-YKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGY 790
G L G Y C C AG+VG++CE + + C S+PCQ+GG C++ Y C C + F GY
Sbjct: 803 GGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGY 862
Query: 791 NCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAP 836
+C+ D C S+PC +G C ++C C + YTG++C L P
Sbjct: 863 HCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
Score = 430 bits (1105), Expect = e-119
Identities = 230/652 (35%), Positives = 316/652 (48%), Gaps = 60/652 (9%)
Query: 145 TDACLS-HPCANGSTC----TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL 199
T CL+ PC NG C T ++C CL+GFTG++C DVNEC CQ+GGTC
Sbjct: 269 TSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNEC-ASQPCQNGGTCT 327
Query: 200 NLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCER 259
+ S++CQCP GF G C++ PC C +GG C Q + + C C G+ G+ CE
Sbjct: 328 HGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQC-QVENGSAVCVCQAGYTGAACEM 386
Query: 260 NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC-TED---VDECLLQPNACQNGGTC 315
++DDC C NGG CVD V Y C C + G C T D D CL P C NGGTC
Sbjct: 387 DVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAP--CHNGGTC 444
Query: 316 ANRNGGYGCVCVNGWSGDDCSENI-DDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCH 374
+ + GY C C G+ G DC E + DDC C G C+ + C CP G GLLC
Sbjct: 445 VDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGANTTL-CQCPLGFFGLLCE 500
Query: 375 LDDACISNPCHKGALCDTNPL----NGQYICTCPQGYKGADCTEDVDECAMANSNPCEHA 430
+ + PC+ C G Y+C C + + + +S+PC +
Sbjct: 501 FEITAM--PCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLP-----SPCDSDPCFNG 553
Query: 431 GKCVNTDGAFHCECLKGYAGPRCE-MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGV 489
G C D ++ CEC +G+ G CE + C S PC+N TC + G + C C F G
Sbjct: 554 GSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGR 613
Query: 490 HCEL-EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCI 548
HCE+ + + C S PC N G C + +++C CPPGF+G C+I C +PC+NG C
Sbjct: 614 HCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCE 673
Query: 549 DHPNGYECQCATGFTGVLCEENIDNCDPDPCHH------GQCQDGIDSYTC--------- 593
D + C C G+ G C+ +D P+ H G + Y C
Sbjct: 674 DRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAP 733
Query: 594 ----ICNPGYMGAICSD-----QIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEI 644
+C P + S+ +IDEC S PCL+ G C D V GY C C G G +CE+
Sbjct: 734 SRIRVCQP---HGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCEL 790
Query: 645 NFDDCASNPCIH-GICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNG 703
D+C ++PC + G C + Y C C GF G C ++D C S+PC+ G C +G
Sbjct: 791 ERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGA 850
Query: 704 FRCICPEGPHHPSCYSQVNECLSNPC-IHGNCTGGLSGYKCLCDAGWVGINC 754
+ C+CPE C + + C S+PC G C + C C G+ G +C
Sbjct: 851 YLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 420 bits (1080), Expect = e-117
Identities = 236/682 (34%), Positives = 324/682 (47%), Gaps = 73/682 (10%)
Query: 787 FKGYNCQVNIDEC--------ASNPCLNQGTCFDD-ISG---YTCHCVLPYTGKNCQTVL 834
F+ + QV + C A PCLN G C DD ++G YTC C+ +TG+ C +
Sbjct: 253 FRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDV 312
Query: 835 APCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGS 894
C+ PC+N C N S+ C C G+ G C C +K C + G C GS
Sbjct: 313 NECASQPCQNGGTCTHGIN--SFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGS 370
Query: 895 YMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTD----M 950
+C C G++G CE D+DDC +PC NGGSC+D V ++CLC F G +C+T
Sbjct: 371 AVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVP 430
Query: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010
+ CLS PC NGGTC D Y C+C GF G+ C + + E C NGG C+ G N+
Sbjct: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE--CRNGGRCL-GANTTL 487
Query: 1011 CLCPVGFTGSFCLHEINE--CSSHP-CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLC 1067
C CP+GF G C EI C+ + C + G C++ G+Y C C + + +L + C
Sbjct: 488 CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASH--SLPSPC 545
Query: 1068 SRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCI 1127
PC N G+C C CP G+ G +C+ +R + C++ G C
Sbjct: 546 DSDPCFNGGSCDAHDDSYTCECPRGFHGKHCE---------KARPHLCSSGPCRNGGTCK 596
Query: 1128 NAGNTHYCQCPLGYTGSYCE-EQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEY 1186
AG ++C CP +TG +CE + D CAS PC +G TC +IG Y+C+C PG+ G +CE
Sbjct: 597 EAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEI 656
Query: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNG-----GQC 1241
C PC NGGTC D F C C G G C+ +D C + G
Sbjct: 657 APSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD-CGPPEEVKHATLRFNGTR 715
Query: 1242 MDRIGGYSCR-------------CLP-GFAGERCEG-DINECLSNPCSSEGSLDCIQLTN 1286
+ + Y+C C P G E + +I+EC S PC GS C
Sbjct: 716 LGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGS--CQDRVA 773
Query: 1287 DYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQS-- 1344
YLC+C + + G HCE D C PC NGG+C N+P ++CRCP GF G C++
Sbjct: 774 GYLCLCSTGYEGAHCELERDECRAHPCRNGGSCR---NLPGAYVCRCPAGFVGVHCETEV 830
Query: 1345 -SCGQVKCRKGEQCVHTASGPRCFCPSP---RDCES---GCASSPCQHGGSCHPQRQPPY 1397
+C C+ G +C C CP CE+ C SSPC G C
Sbjct: 831 DACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGS-- 888
Query: 1398 YSCQCAPPFSGSRCELYTAPPS 1419
+SC C ++G C PP+
Sbjct: 889 HSCTCKVGYTGEDCAKELFPPT 910
Score = 420 bits (1080), Expect = e-117
Identities = 214/633 (33%), Positives = 294/633 (46%), Gaps = 73/633 (11%)
Query: 464 PCQNDATCLDKI----GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
PC N C+D +TC C+ GF G C L++NEC S PC N G C +N F+C
Sbjct: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
Query: 520 CPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPC 579
CP GF GP C+ C + C +G +C C C G+TG CE ++D+C PDPC
Sbjct: 337 CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPC 396
Query: 580 -HHGQCQDGIDSYTCICNPGYMGAICSDQI----DECYSSPCLNDGRCIDLVNGYQCNCQ 634
+ G C D + +YTC+C + G C D C S+PC N G C+D GY C C
Sbjct: 397 LNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECP 456
Query: 635 PGTSGVNCEINF-DDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDI---------- 683
G G++C DDC C +G G N C C GF G C +I
Sbjct: 457 EGFMGLDCRERVPDDCE---CRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQ 513
Query: 684 -----------------------------DECASNPCRKGATCINGVNGFRCICPEGPHH 714
C S+PC G +C + + C CP G H
Sbjct: 514 CPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHG 573
Query: 715 PSCY-SQVNECLSNPCIHGN-CTGGLSGYKCLCDAGWVGINCEVDK-NECLSNPCQNGGT 771
C ++ + C S PC +G C Y C C + G +CE+ K + C S PC NGGT
Sbjct: 574 KHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGT 633
Query: 772 CDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQ 831
C + + Y+C C GF G +C++ C +PC+N GTC D + + CHC Y G+ CQ
Sbjct: 634 CFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQ 693
Query: 832 TVLAPCSPNPCENAAVCKESPNFES---YTC-------------LCAPG--WQGQRCTID 873
+ P ++A + + Y C +C P W ++
Sbjct: 694 AEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLE 753
Query: 874 IDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTF 933
IDEC S+PC++ G C + Y+C C G+ G CE + D+C A+PC+NGGSC + +
Sbjct: 754 IDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAY 813
Query: 934 SCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTE 993
C C GF G C+T+++ C S PC++GG C +Y C C F G HCE + C
Sbjct: 814 VCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFS 873
Query: 994 SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI 1026
S C G C+ S SC C VG+TG C E+
Sbjct: 874 SPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 417 bits (1073), Expect = e-116
Identities = 240/658 (36%), Positives = 302/658 (45%), Gaps = 53/658 (8%)
Query: 101 CQYSTSHPCFVSRPCLNGGTC---HMLSRDTYECTCQVGFTGKECQW-TDACLSHPCANG 156
C ++TS C RPCLNGG C + +Y C+C GFTG+ C + C S PC NG
Sbjct: 265 CGHTTS-VCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNG 323
Query: 157 STCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQ 216
TCT N F C+C GF G CET + CD CQHGG C GS C C G+TG
Sbjct: 324 GTCTHGINSFRCQCPAGFGGPTCETAQSPCDTK-ECQHGGQCQVENGSAVCVCQAGYTGA 382
Query: 217 YCDSLYVPCAPSPCVNGGTCRQ-TGDFTFECNCLPGFEGSTCERN----IDDCPNHRCQN 271
C+ C+P PC+NGG+C G++T C C F+G CE D C + C N
Sbjct: 383 ACEMDVDDCSPDPCLNGGSCVDLVGNYT--CLCAEPFKGLRCETGDHPVPDACLSAPCHN 440
Query: 272 GGVCVDGVNTYNCRCPPQWTGQFCTEDV-DECLLQPNACQNGGTCANRNGGYGCVCVNGW 330
GG CVD Y C CP + G C E V D+C C+NGG C N C C G+
Sbjct: 441 GGTCVDADQGYVCECPEGFMGLDCRERVPDDC-----ECRNGGRCLGANTTL-CQCPLGF 494
Query: 331 SGDDCSENID--DCAF-ASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKG 387
G C I C C G C++ S+ C+C L C S+PC G
Sbjct: 495 FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC-HTDHNASHSLPSPCDSDPCFNG 553
Query: 388 ALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKG 447
CD + + Y C CP+G+ G C + + +S PC + G C G +HC C
Sbjct: 554 GSCDAH--DDSYTCECPRGFHGKHCEKARPH--LCSSGPCRNGGTCKEAGGEYHCSCPYR 609
Query: 448 YAGPRCEM-DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNN 506
+ G CE+ + C S PC N TC IG + C C PGF G HCE+ + C +PCVN
Sbjct: 610 FTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNG 669
Query: 507 GQCVDKVNRFQCLCPPGFTGPVCQIDIDDCS-------STPCLNGAK-----CIDHPNGY 554
G C D+ F C C G+ G CQ ++ DC +T NG + GY
Sbjct: 670 GTCEDRDTDFFCHCQAGYMGRRCQAEV-DCGPPEEVKHATLRFNGTRLGAVALYACDRGY 728
Query: 555 ECQCATGFT-----GVLCEE----NIDNCDPDPC-HHGQCQDGIDSYTCICNPGYMGAIC 604
+ GV E ID C PC H G CQD + Y C+C+ GY GA C
Sbjct: 729 SLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHC 788
Query: 605 SDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIH-GICMDGI 663
+ DEC + PC N G C +L Y C C G GV+CE D C S+PC H G C G
Sbjct: 789 ELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGG 848
Query: 664 NRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV 721
Y CVC F G C D C S+PC C+ C C G C ++
Sbjct: 849 GAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 412 bits (1058), Expect = e-114
Identities = 225/652 (34%), Positives = 299/652 (45%), Gaps = 91/652 (13%)
Query: 650 ASNPCIHG-----ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGF 704
A PC++G C+ G Y+C C GFTG+RC++D++ECAS PC+ G TC +G+N F
Sbjct: 274 ALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSF 333
Query: 705 RCICPEGPHHPSCYSQVNECLSNPCIHGN-CTGGLSGYKCLCDAGWVGINCEVDKNECLS 763
RC CP G P+C + + C + C HG C C+C AG+ G CE+D ++C
Sbjct: 334 RCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSP 393
Query: 764 NPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNI----DECASNPCLNQGTCFDDISGYTC 819
+PC NGG+C +LV Y C C + FKG C+ D C S PC N GTC D GY C
Sbjct: 394 DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVC 453
Query: 820 HCVLPYTGKNCQ-------------------TVLA------------------PCSPNP- 841
C + G +C+ T L PC+ N
Sbjct: 454 ECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQ 513
Query: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPP 901
C + C E SY C+C C S PC N G C SY CECP
Sbjct: 514 CPDGGYCMEHGG--SYLCVCHTDHNASHSLPS--PCDSDPCFNGGSCDAHDDSYTCECPR 569
Query: 902 GFSGMDCEEDIDD-CLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM-NECLSEPCK 959
GF G CE+ C + PC+NGG+C + + C C FTG C+ + C S PC
Sbjct: 570 GFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCH 629
Query: 960 NGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTG 1019
NGGTC Y+ Y C C GF G HCE + C S C NGGTC D F C C G+ G
Sbjct: 630 NGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMG 689
Query: 1020 SFCLHEIN----ECSSHPCLN-EGTCVDGLGTYRCS-------------C-PLGYTGKNC 1060
C E++ E H L GT + + Y C C P G +
Sbjct: 690 RRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPP 749
Query: 1061 QTL-VNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHL 1119
Q L ++ C PC + G+C + A CLC +G+ GA+C++ C H
Sbjct: 750 QCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRA----------HP 799
Query: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179
C++ G C N + C+CP G+ G +CE ++D C S+PCQHG C G Y C C +
Sbjct: 800 CRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESF 859
Query: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCAR 1231
G +CE D C + PC G C+ C+C G G +DCA+
Sbjct: 860 FGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTG-------EDCAK 904
Score = 392 bits (1007), Expect = e-108
Identities = 224/643 (34%), Positives = 304/643 (47%), Gaps = 54/643 (8%)
Query: 73 CQNGGTCVAQAMLGKA--TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTC-HMLSRDTY 129
C NGG C+ + G TC C SGFTG C + S+PC NGGTC H + +++
Sbjct: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNE--CASQPCQNGGTCTHGI--NSF 333
Query: 130 ECTCQVGFTGKECQWTDA-CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188
C C GF G C+ + C + C +G C C C G+TG CE DV++C
Sbjct: 334 RCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCS- 392
Query: 189 PGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVP----CAPSPCVNGGTCRQTGDFTF 244
P C +GG+C++L G+Y C C + F G C++ P C +PC NGGTC D +
Sbjct: 393 PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC-VDADQGY 451
Query: 245 ECNCLPGFEGSTC-ERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECL 303
C C GF G C ER DDC C+NGG C+ G NT C+CP + G C ++
Sbjct: 452 VCECPEGFMGLDCRERVPDDC---ECRNGGRCL-GANTTLCQCPLGFFGLLCEFEITAMP 507
Query: 304 LQPNA-CQNGGTCANRNGGYGCVCVNGWSGDDCSENI-DDCAFASCTPGSTCIDRVASFS 361
N C +GG C G Y CVC + + S ++ C C G +C S++
Sbjct: 508 CNMNTQCPDGGYCMEHGGSYLCVC---HTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYT 564
Query: 362 CMCPEGKAGLLCH--LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADC-TEDVDE 418
C CP G G C C S PC G C G+Y C+CP + G C D
Sbjct: 565 CECPRGFHGKHCEKARPHLCSSGPCRNGGTC--KEAGGEYHCSCPYRFTGRHCEIGKPDS 622
Query: 419 CAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGF 478
CA S PC + G C + G + C+C G++G CE+ + C PC N TC D+ F
Sbjct: 623 CA---SGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 679
Query: 479 TCLCMPGFKGVHCELEIN-----ECQSNPCVNNGQCVDKVNRFQCLCPPGFTGP----VC 529
C C G+ G C+ E++ E + NG + V + C + P VC
Sbjct: 680 FCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVC 739
Query: 530 Q-----------IDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDP 578
Q ++ID+C S PCL+G C D GY C C+TG+ G CE D C P
Sbjct: 740 QPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP 799
Query: 579 CHH-GQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGT 637
C + G C++ +Y C C G++G C ++D C SSPC + GRC Y C C
Sbjct: 800 CRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESF 859
Query: 638 SGVNCEINFDDCASNPC-IHGICMDGINRYSCVCSPGFTGQRC 679
G +CE D C S+PC G C+ +SC C G+TG+ C
Sbjct: 860 FGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 390 bits (1002), Expect = e-108
Identities = 208/653 (31%), Positives = 296/653 (45%), Gaps = 89/653 (13%)
Query: 374 HLDDACIS-NPCHKGALCDTNPLNGQ--YICTCPQGYKGADCTEDVDECAMANSNPCEHA 430
H C++ PC G C + + G Y C+C G+ G C DV+ECA S PC++
Sbjct: 267 HTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECA---SQPCQNG 323
Query: 431 GKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVH 490
G C + +F C+C G+ GP CE + C + CQ+ C + G C+C G+ G
Sbjct: 324 GTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAA 383
Query: 491 CELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQID----IDDCSSTPCLNGAK 546
CE+++++C +PC+N G CVD V + CLC F G C+ D C S PC NG
Sbjct: 384 CEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGT 443
Query: 547 CIDHPNGYECQCATGFTGVLCEENI-DNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICS 605
C+D GY C+C GF G+ C E + D+C+ C +G G ++ C C G+ G +C
Sbjct: 444 CVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGANTTLCQCPLGFFGLLCE 500
Query: 606 DQI---------------------------------------DECYSSPCLNDGRCIDLV 626
+I C S PC N G C
Sbjct: 501 FEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHD 560
Query: 627 NGYQCNCQPGTSGVNCE-INFDDCASNPCIH-GICMDGINRYSCVCSPGFTGQRCNI-DI 683
+ Y C C G G +CE C+S PC + G C + Y C C FTG+ C I
Sbjct: 561 DSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKP 620
Query: 684 DECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIH-GNCTGGLSGYK 742
D CAS PC G TC + + ++C CP G C + C +PC++ G C + +
Sbjct: 621 DSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFF 680
Query: 743 CLCDAGWVGINCEVD-----KNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYN------ 791
C C AG++G C+ + E + GT V Y C +GY+
Sbjct: 681 CHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACD-----RGYSLSAPSR 735
Query: 792 ---CQ-----------VNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPC 837
CQ + IDEC S PCL+ G+C D ++GY C C Y G +C+ C
Sbjct: 736 IRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDEC 795
Query: 838 SPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMC 897
+PC N C+ P +Y C C G+ G C ++D C S PC + G C + G+Y+C
Sbjct: 796 RAHPCRNGGSCRNLPG--AYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLC 853
Query: 898 ECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM 950
CP F G CE D C ++PC G C+ + SC C G+TG+ C ++
Sbjct: 854 VCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 390 bits (1001), Expect = e-107
Identities = 220/647 (34%), Positives = 301/647 (46%), Gaps = 59/647 (9%)
Query: 34 PCVNEGMCV---TYHNGTGYCKCPEGFLGEYCQHRD--PCEKNRCQNGGTCVAQAMLGKA 88
PC+N G C+ N + C C GF G C H D C CQNGGTC +
Sbjct: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRC-HLDVNECASQPCQNGGTCTHG--INSF 333
Query: 89 TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW-TDA 147
C+C +GF G C+ + S PC ++ C +GG C + + C CQ G+TG C+ D
Sbjct: 334 RCQCPAGFGGPTCETAQS-PC-DTKECQHGGQC-QVENGSAVCVCQAGYTGAACEMDVDD 390
Query: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGS 204
C PC NG +C + ++C C F G +CET V + + C +GGTC++
Sbjct: 391 CSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQG 450
Query: 205 YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC 264
Y C+CP+GF G C VP C NGG C G T C C GF G CE I
Sbjct: 451 YVCECPEGFMGLDCRE-RVP-DDCECRNGGRC--LGANTTLCQCPLGFFGLLCEFEITAM 506
Query: 265 P---NHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG 321
P N +C +GG C++ +Y C C C P C NGG+C +
Sbjct: 507 PCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLP--SPCDSDP--CFNGGSCDAHDDS 562
Query: 322 YGCVCVNGWSGDDCSENIDD-CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHL--DDA 378
Y C C G+ G C + C+ C G TC + + C CP G C + D+
Sbjct: 563 YTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDS 622
Query: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438
C S PCH G C G+Y C CP G+ G C C +PC + G C + D
Sbjct: 623 CASGPCHNGGTC--FHYIGKYKCDCPPGFSGRHCEIAPSPCF---RSPCVNGGTCEDRDT 677
Query: 439 AFHCECLKGYAGPRCEMDIN-----ECHSDPCQNDATCLDKIGGFTC------------- 480
F C C GY G RC+ +++ E + + T L + + C
Sbjct: 678 DFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIR 737
Query: 481 LCMPGFKGVHCE----LEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC 536
+C P GV E LEI+EC+S PC++ G C D+V + CLC G+ G C+++ D+C
Sbjct: 738 VCQP--HGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDEC 795
Query: 537 SSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHH-GQCQDGIDSYTCIC 595
+ PC NG C + P Y C+C GF GV CE +D CD PC H G+C+ G +Y C+C
Sbjct: 796 RAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVC 855
Query: 596 NPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNC 642
+ G C D C+SSPC G C+ + C C+ G +G +C
Sbjct: 856 PESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 362 bits (929), Expect = 3e-99
Identities = 226/686 (32%), Positives = 305/686 (44%), Gaps = 101/686 (14%)
Query: 908 CEEDIDDCLA-NPCQNGGSCMD----GVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGG 962
C CLA PC NGG C+D G +++C CL GFTG +C D+NEC S+PC+NGG
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 963 TCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC 1022
TC+ +NS+ C+C AGF G CE + C C +GG C S C+C G+TG+ C
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 1023 LHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQT----LVNLCSRSPCKNKGTC 1078
++++CS PCLN G+CVD +G Y C C + G C+T + + C +PC N GTC
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
Query: 1079 VQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCP 1138
V C CP G+ G C R V + C++ G C+ A NT CQCP
Sbjct: 445 VDADQGYVCECPEGFMGLDC------------RERVPDDCECRNGGRCLGA-NTTLCQCP 491
Query: 1139 LGYTGSYCEEQLDECASN---PCQHGATCSDFIGGYRCECVPGYQGVNCEYEV-DECQNQ 1194
LG+ G CE ++ N C G C + G Y C C + N + + C +
Sbjct: 492 LGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC---HTDHNASHSLPSPCDSD 548
Query: 1195 PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDD-CARGPHCLNGGQCMDRIGGYSCRCL 1253
PC NGG+C + + C CP G G CE+ C+ GP C NGG C + G Y C C
Sbjct: 549 PCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGP-CRNGGTCKEAGGEYHCSCP 607
Query: 1254 PGFAGERCE-GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMP 1312
F G CE G + C S PC + G+ C Y C C F+GRHCE C + P
Sbjct: 608 YRFTGRHCEIGKPDSCASGPCHNGGT--CFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSP 665
Query: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTA---SGPRCFCP 1369
C+NGGTC + F C C G+ G RCQ+ +V C E+ H +G R
Sbjct: 666 CVNGGTC---EDRDTDFFCHCQAGYMGRRCQA---EVDCGPPEEVKHATLRFNGTRLGAV 719
Query: 1370 SPRDCESG-----------------------------CASSPCQHGGSCHPQRQPPYYSC 1400
+ C+ G C S PC HGGSC Q + Y C
Sbjct: 720 ALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSC--QDRVAGYLC 777
Query: 1401 QCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTME 1460
C+ + G+ CEL C + C + G C ++ C+ G + E
Sbjct: 778 LCSTGYEGAHCEL-------ERDECRAHPCRN---GGSCRNLPGAYVCRCPAGFVGVHCE 827
Query: 1461 NPWANCSSPLPCWDYINNQCDE-----LCNTVECLFDNFECQGNSKTCKYDKYCADHFKD 1515
C S PC +C+ LC E F + C+ S C + C
Sbjct: 828 TEVDACDSS-PCQH--GGRCESGGGAYLCVCPESFF-GYHCETVSDPC-FSSPCGGR--- 879
Query: 1516 NHCDQGCNSEEC----GWDGLDCAAD 1537
+C S C G+ G DCA +
Sbjct: 880 GYCLASNGSHSCTCKVGYTGEDCAKE 905
Score = 348 bits (894), Expect = 3e-95
Identities = 212/651 (32%), Positives = 281/651 (43%), Gaps = 100/651 (15%)
Query: 3 ALRPALLWALLALWLCCAAPAHALQCRDGY--------------EPCVNEGMCVTYHNGT 48
ALRP L P++ C G+ +PC N G C T+ +
Sbjct: 274 ALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTC-THGINS 332
Query: 49 GYCKCPEGFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSH 107
C+CP GF G C+ + PC+ CQ+GG C Q G A C C +G+TG C+
Sbjct: 333 FRCQCPAGFGGPTCETAQSPCDTKECQHGGQC--QVENGSAVCVCQAGYTGAACEMDVDD 390
Query: 108 PCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW-----TDACLSHPCANGSTCTTV 162
C PCLNGG+C L + Y C C F G C+ DACLS PC NG TC
Sbjct: 391 -CSPD-PCLNGGSCVDLVGN-YTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDA 447
Query: 163 ANQFSCKCLTGFTGQKCETDV-NECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCD-- 219
+ C+C GF G C V ++C+ C++GG CL + CQCP GF G C+
Sbjct: 448 DQGYVCECPEGFMGLDCRERVPDDCE----CRNGGRCLGA-NTTLCQCPLGFFGLLCEFE 502
Query: 220 -------------------------------------SLYVPCAPSPCVNGGTCRQTGDF 242
SL PC PC NGG+C D
Sbjct: 503 ITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSC-DAHDD 561
Query: 243 TFECNCLPGFEGSTCERNIDD-CPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCT-EDVD 300
++ C C GF G CE+ C + C+NGG C + Y+C CP ++TG+ C D
Sbjct: 562 SYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPD 621
Query: 301 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF 360
C P C NGGTC + G Y C C G+SG C C + C G TC DR F
Sbjct: 622 SCASGP--CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 679
Query: 361 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNP--LNGQYICTCPQGY----------- 407
C C G G C + C K A N L + C +GY
Sbjct: 680 FCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVC 739
Query: 408 -------KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINEC 460
+ C E +DEC S PC H G C + + C C GY G CE++ +EC
Sbjct: 740 QPHGVWSEPPQCLE-IDEC---RSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDEC 795
Query: 461 HSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLC 520
+ PC+N +C + G + C C GF GVHCE E++ C S+PC + G+C + C+C
Sbjct: 796 RAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVC 855
Query: 521 PPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI 571
P F G C+ D C S+PC C+ + C C G+TG C + +
Sbjct: 856 PESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 53.5 bits (127), Expect = 2e-06
Identities = 32/96 (33%), Positives = 46/96 (47%), Gaps = 8/96 (8%)
Query: 761 CLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPC---LNQGTCFDDISGY 817
C NPCQNGGTC + + C C GFKG C++ + S PC ++ F G
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPCTRLFSETKAFPVWEGG 1369
Query: 818 TCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPN 853
CH V + Q + C CE+ ++ K++PN
Sbjct: 1370 VCHHVYKRVYRVHQDI---CFKESCESTSL-KKTPN 1401
Score = 50.8 bits (120), Expect = 2e-05
Identities = 21/45 (46%), Positives = 29/45 (64%), Gaps = 1/45 (2%)
Query: 914 DCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPC 958
+C NPCQNGG+C+ G + SC C PGF G +C+ + +S PC
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 47.4 bits (111), Expect = 2e-04
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 12/87 (13%)
Query: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYS---TSHPC------FVSRPCLNG 118
C +N CQNGGTCV A +C C GF G C+ + S PC + P G
Sbjct: 1311 CSENPCQNGGTCVPGA--DAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEG 1368
Query: 119 GTCHMLSRDTYECTCQVGFTGKECQWT 145
G CH + + Y + F + C+ T
Sbjct: 1369 GVCHHVYKRVYRVHQDICFK-ESCEST 1394
Score = 47.4 bits (111), Expect = 2e-04
Identities = 26/66 (39%), Positives = 32/66 (48%), Gaps = 9/66 (13%)
Query: 1378 CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKA--- 1434
C+ +PCQ+GG+C P +SC C P F G RCEL S P C + KA
Sbjct: 1311 CSENPCQNGGTCVPGADA--HSCDCGPGFKGRRCELACIKVSRP---CTRLFSETKAFPV 1365
Query: 1435 -RDGVC 1439
GVC
Sbjct: 1366 WEGGVC 1371
Score = 47.0 bits (110), Expect = 2e-04
Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 21/83 (25%)
Query: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCF 1367
C + PC NGGTC + D C C PGF G RC+ +C +V C S + F
Sbjct: 1311 CSENPCQNGGTCVPGA---DAHSCDCGPGFKGRRCELACIKV----SRPCTRLFSETKAF 1363
Query: 1368 CPSPRDCESGCASSPCQHGGSCH 1390
P GG CH
Sbjct: 1364 --------------PVWEGGVCH 1372
Score = 46.6 bits (109), Expect = 3e-04
Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 4/61 (6%)
Query: 823 LPYTG-KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP 881
LP G K+ V CS NPC+N C P ++++C C PG++G+RC + + +S+P
Sbjct: 1296 LPEHGSKDIGNVPGNCSENPCQNGGTCV--PGADAHSCDCGPGFKGRRCELACIK-VSRP 1352
Query: 882 C 882
C
Sbjct: 1353 C 1353
Score = 44.7 bits (104), Expect = 0.001
Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 648 DCASNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRK 693
+C+ NPC +G C+ G + +SC C PGF G+RC + + S PC +
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPCTR 1355
Score = 44.7 bits (104), Expect = 0.001
Identities = 20/44 (45%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPC 503
C +PCQN TC+ +C C PGFKG CEL + S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
Score = 44.7 bits (104), Expect = 0.001
Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 1029 CSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPC 1072
CS +PC N GTCV G + C C G+ G+ C+ SR PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSR-PC 1353
Score = 44.3 bits (103), Expect = 0.002
Identities = 16/33 (48%), Positives = 19/33 (57%)
Query: 1191 CQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCE 1223
C PCQNGGTC+ + C C PG +G CE
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 43.9 bits (102), Expect = 0.002
Identities = 15/33 (45%), Positives = 21/33 (63%)
Query: 1153 CASNPCQHGATCSDFIGGYRCECVPGYQGVNCE 1185
C+ NPCQ+G TC + C+C PG++G CE
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 42.4 bits (98), Expect = 0.006
Identities = 16/33 (48%), Positives = 20/33 (60%)
Query: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE 180
C +PC NG TC A+ SC C GF G++CE
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 42.4 bits (98), Expect = 0.006
Identities = 17/32 (53%), Positives = 21/32 (65%)
Query: 991 CTESSCFNGGTCVDGINSFSCLCPVGFTGSFC 1022
C+E+ C NGGTCV G ++ SC C GF G C
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
Score = 42.0 bits (97), Expect = 0.007
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 1228 DCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCS 1274
+C+ P C NGG C+ +SC C PGF G RCE + +S PC+
Sbjct: 1310 NCSENP-CQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPCT 1354
Score = 42.0 bits (97), Expect = 0.007
Identities = 15/33 (45%), Positives = 20/33 (60%)
Query: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCE 985
C PC+NGGTC ++++C C GF G CE
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 41.6 bits (96), Expect = 0.010
Identities = 17/34 (50%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE 258
C+ +PC NGGTC D C+C PGF+G CE
Sbjct: 1311 CSENPCQNGGTCVPGAD-AHSCDCGPGFKGRRCE 1343
Score = 40.8 bits (94), Expect = 0.017
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 263 DCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
+C + CQNGG CV G + ++C C P + G+ C
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
Score = 40.8 bits (94), Expect = 0.017
Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 114 PCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPC 153
PC NGGTC + D + C C GF G+ C+ +S PC
Sbjct: 1315 PCQNGGTC-VPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
Score = 40.4 bits (93), Expect = 0.022
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 535 DCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE 568
+CS PC NG C+ + + C C GF G CE
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 40.4 bits (93), Expect = 0.022
Identities = 15/34 (44%), Positives = 18/34 (52%)
Query: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
C NPC N G CV + C C PGF G C++
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
Score = 38.9 bits (89), Expect = 0.063
Identities = 13/34 (38%), Positives = 19/34 (55%)
Query: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEI 644
C +PC N G C+ + + C+C PG G CE+
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
Score = 38.5 bits (88), Expect = 0.083
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 877 CISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE 909
C PC N G C ++ C+C PGF G CE
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 38.1 bits (87), Expect = 0.11
Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
Query: 573 NCDPDPCHHG-QCQDGIDSYTCICNPGYMGAIC 604
NC +PC +G C G D+++C C PG+ G C
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
Score = 38.1 bits (87), Expect = 0.11
Identities = 14/33 (42%), Positives = 20/33 (60%)
Query: 423 NSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEM 455
+ NPC++ G CV A C+C G+ G RCE+
Sbjct: 1312 SENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
Score = 37.7 bits (86), Expect = 0.14
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 15/76 (19%)
Query: 187 DIPGHC-----QHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGD 241
++PG+C Q+GGTC+ ++ C C GF G+ C+ + + PC
Sbjct: 1306 NVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVS-RPCTR--------- 1355
Query: 242 FTFECNCLPGFEGSTC 257
E P +EG C
Sbjct: 1356 LFSETKAFPVWEGGVC 1371
Score = 36.6 bits (83), Expect = 0.31
Identities = 14/34 (41%), Positives = 19/34 (55%)
Query: 1067 CSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDV 1100
CS +PC+N GTCV C C G+ G C++
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
Score = 35.4 bits (80), Expect = 0.70
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 1117 EHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPC 1158
E+ CQ+ G C+ + H C C G+ G CE + S PC
Sbjct: 1313 ENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 35.4 bits (80), Expect = 0.70
Identities = 25/94 (26%), Positives = 34/94 (36%), Gaps = 16/94 (17%)
Query: 307 NACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPE 366
N CQNGGTC + C C G+ G C +C S R+ S + P
Sbjct: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRCE--------LACIKVSRPCTRLFSETKAFPV 1365
Query: 367 GKAGLLCHL--------DDACISNPCHKGALCDT 392
+ G+ H+ D C C +L T
Sbjct: 1366 WEGGVCHHVYKRVYRVHQDICFKESCESTSLKKT 1399
Score = 34.3 bits (77), Expect = 1.6
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 334 DCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPC 384
+CSEN C G TC+ + SC C G G C L +S PC
Sbjct: 1310 NCSEN-------PCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
Score = 34.3 bits (77), Expect = 1.6
Identities = 11/26 (42%), Positives = 15/26 (57%)
Query: 686 CASNPCRKGATCINGVNGFRCICPEG 711
C+ NPC+ G TC+ G + C C G
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPG 1336
Score = 32.7 bits (73), Expect = 4.5
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 6/46 (13%)
Query: 724 CLSNPCIHGN-CTGGLSGYKCLCDAGWVGINCEVDKNECL--SNPC 766
C NPC +G C G + C C G+ G CE+ C+ S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL---ACIKVSRPC 1353
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 405 bits (1042), Expect = e-112
Identities = 430/1528 (28%), Positives = 555/1528 (36%), Gaps = 387/1528 (25%)
Query: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP-GHCQHGGTCLNLPGSYQ 206
C + C +G C + Q C C GF G +C+ DV+EC G CQH C+N PGSY
Sbjct: 128 CSASLCFHGGRCVPGSAQ-PCHCPPGFQGPRCQYDVDECRTHNGGCQH--RCVNTPGSYL 184
Query: 207 CQCPQGFTGQYCDSLYVPCAPSPCVNGGTCR----QTGDFTFECNCLPGFE----GSTCE 258
C+C GF + DS S + G C+ Q C C PGF+ G C
Sbjct: 185 CECKPGFR-LHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 243
Query: 259 RNIDDCPN------HRCQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDECLLQPNACQ 310
R C N HRCQ V G+ C Q G+ C EDVDEC C
Sbjct: 244 RR-SPCANRNGSCMHRCQ----VVRGLARCECHVGYQLAADGKAC-EDVDECAAGLAQCA 297
Query: 311 NGGTCANRNGGYGCVCVNGWS----GDDC----SENIDDCAFASCTPGSTCIDRVASFSC 362
+G C N G + CVC G+ G C E ++ C + C A C
Sbjct: 298 HG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLC 355
Query: 363 MCPEGKA----GLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYK----GADCTE 414
CP G C D C +PC + +C NP G Y C C GY+ G C E
Sbjct: 356 TCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNP--GGYECGCYAGYRLSADGCGC-E 411
Query: 415 DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDK 474
DVDECA + CEH C N G+F C C GY R D C P + LD
Sbjct: 412 DVDECASSRGG-CEH--HCTNLAGSFQCSCEAGY---RLHEDRRGC--SPLEEPMVDLDG 463
Query: 475 IGGFTCLCMPGFKGVHCEL-------EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGP 527
F +P + EL ++ + + + + +F CL G
Sbjct: 464 ELPFV-RPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTE--KFVCL--DDSFGH 518
Query: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDP----CHHG- 582
C + DDC NG C+ +G C C G+TG++C E C PD C
Sbjct: 519 DCSLTCDDCR-----NGGTCLLGLDG--CDCPEGWTGLICNET---CPPDTFGKNCSFSC 568
Query: 583 QCQDG--IDSYT--CICNPGYMGAICSDQIDECYSSP-------CLNDGRCIDLVNGYQC 631
CQ+G DS T C C PG G C D + Y C N GRC L C
Sbjct: 569 SCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA--C 626
Query: 632 NCQPGTSGVNCEINFDDCASNPCIHGICM------------DGINRYSCVCSPGFTGQRC 679
C PG G C + A P C DG SC C GF G+RC
Sbjct: 627 LCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDG----SCSCKAGFRGERC 682
Query: 680 NIDIDECASNP-CRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGL 738
+ + P C + TC GV +C S EC C G
Sbjct: 683 QAECELGYFGPGCWQACTCPVGV--------------ACDSVSGECGKR------CPAGF 722
Query: 739 SGYKC--LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNI 796
G C C G G+NC S+ C GG + V G +C C G G +C+ +
Sbjct: 723 QGEDCGQECPVGTFGVNC--------SSSCSCGGAPCHGVTG-QCRCPPGRTGEDCEAD- 772
Query: 797 DECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFES 856
C + G C + P C++AA C E+
Sbjct: 773 -------------CPEGRWGLGCQEICP----------------ACQHAARCDP----ET 799
Query: 857 YTCLCAPGWQGQRCTIDI-------DECISK-PCMNHGLCHNTQGSYMCECPPGFSGMDC 908
CLC PG+ G RC D+ C ++ C N G CH G C C PG++G C
Sbjct: 800 GACLCLPGFVGSRCQ-DVCPAGWYGPSCQTRCSCANDGHCHPATGH--CSCAPGWTGFSC 856
Query: 909 EEDID------DCLANPCQ---NGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEP-- 957
+ D DC ++PC GSC D ++ CLC G+ G +C+ + P
Sbjct: 857 QRACDTGHWGPDC-SHPCNCSAGHGSC-DAISGL-CLCEAGYVGPRCEQQCPQGHFGPGC 913
Query: 958 -----CKNGGTCSDYVNSYTCKCQAGFDGVHCENNIN------ECTESSCFNGGTCVDGI 1006
C++G C D+V+ C C AG+ G CE+ +C + G D +
Sbjct: 914 EQRCQCQHGAAC-DHVSG-ACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAV 971
Query: 1007 NSFSCLCPVGFTGSFCLHEI------NECSSH-PCLNEGTCVDGLGTYRCS--------- 1050
N SCLCP G G C + CS C N +C G C+
Sbjct: 972 NG-SCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCL 1030
Query: 1051 --CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIA 1108
CP G G NC+ + C C+N GTC C CP GWAG C+ + D+
Sbjct: 1031 QACPAGLYGDNCR---HSCL---CQNGGTC--DPVSGHCACPEGWAGLACEKECLPRDVR 1082
Query: 1109 ASRRGVLVEHLCQHSGVCINAG----NTHYCQCPLGYTGSYCEEQL------DECASN-P 1157
A C+HSG C+N G +T C CP G+TG C+ + CA
Sbjct: 1083 AG---------CRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 1133
Query: 1158 CQHGATCSDFIGGYRCECVPGYQGVNCEYEV------DECQNQPCQNGG---TCIDLVNH 1208
C GA C G C C PG+ G CE ++C Q CQ G C
Sbjct: 1134 CPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCA-QMCQCPGENPACHPATG- 1189
Query: 1209 FKCSCPPGTRGLLCEENIDDCARGPHC------LNGGQCMDRIGGYSCRCLPGFAGERC- 1261
CSC G G C++ GP C LNGG C G +CRC GF G C
Sbjct: 1190 -TCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATG--ACRCPTGFLGTDCN 1246
Query: 1262 ----EGDINECLSNPCSSEGSLDCIQLTN--------------------------DYLCV 1291
+G ++ C C +T ++ C
Sbjct: 1247 LTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS 1306
Query: 1292 CRSA---------------FTGRHCETFVDVCP----------QMPCLNGGTCAVASNMP 1326
CR+ +TGRHCE CP + C N TC A+
Sbjct: 1307 CRNGGLCHASNGSCSCGLGWTGRHCEL---ACPPGRYGAACHLECSCHNNSTCEPATGTC 1363
Query: 1327 D------GFICR--CPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR------ 1372
G C CPPGF GA CQ C C+ G C SG RC CP+
Sbjct: 1364 RCGPGFYGQACEHPCPPGFHGAGCQGLCW---CQHGAPC-DPISG-RCLCPAGFHGHFCE 1418
Query: 1373 ----------------DCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELY-- 1414
DC+ G P C P R + C G C L+
Sbjct: 1419 RGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCD 1478
Query: 1415 -----TAPPSTPPATCLSQYCADKARDG 1437
P + C+ Y R+G
Sbjct: 1479 CGGGADCDPVSGQCHCVDGYMGPTCREG 1506
Score = 390 bits (1001), Expect = e-107
Identities = 433/1544 (28%), Positives = 554/1544 (35%), Gaps = 371/1544 (24%)
Query: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGT---CVAQAMLGKATC 90
C + G CV C CP GF G CQ+ D C R NGG CV G C
Sbjct: 133 CFHGGRCVP--GSAQPCHCPPGFQGPRCQYDVDEC---RTHNGGCQHRCVNTP--GSYLC 185
Query: 91 RCASGFTGEDCQYSTSHPCFVSRPCL--NGGT---CHMLSRDTYECTCQVGFT----GKE 141
C GF ++ S C C NGG C L+ + C C+ GF G+
Sbjct: 186 ECKPGFR----LHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRH 241
Query: 142 CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNECDIP-GHCQHGG 196
C C + + C V C+C G+ G+ CE DV+EC C HG
Sbjct: 242 CVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDECAAGLAQCAHG- 299
Query: 197 TCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGST 256
CLN GS++C C G+ G +G
Sbjct: 300 -CLNTQGSFKCVCHAGYE-----------------------------------LGADGRQ 323
Query: 257 CERNIDDCPNHRCQNGGVCVDGVNTYN----CRCPPQW---TGQFCTEDVDECLLQPNAC 309
C R + N N G C G + + C CP + T Q DVD+C P C
Sbjct: 324 CYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP-CC 382
Query: 310 QNGGTCANRNGGYGCVCVNGW--SGDDCS-ENIDDCAFASCTPGSTCIDRVASFSCMCPE 366
Q C N GGY C C G+ S D C E++D+CA + C + SF C C
Sbjct: 383 QQ--VCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSC-- 438
Query: 367 GKAGLLCHLDD---ACISNPC--------------HKGALCDTNP--------------- 394
+AG H D + + P H L D P
Sbjct: 439 -EAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEA 497
Query: 395 -LNGQYICT----CPQGYKGADCTEDVDECAMANSNPCEHAGKCV-NTDGAFHCECLKGY 448
L G++ T C G DC+ D+C + G C+ DG C+C +G+
Sbjct: 498 ELRGEHTLTEKFVCLDDSFGHDCSLTCDDC--------RNGGTCLLGLDG---CDCPEGW 546
Query: 449 AGPRCEMDI-------NECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI------ 495
G C N S CQN TC D + G C C PG G +CE
Sbjct: 547 TGLICNETCPPDTFGKNCSFSCSCQNGGTC-DSVTG-ACRCPPGVSGTNCEDGCPKGYYG 604
Query: 496 NECQSN-PCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP-CLNGAKCI----- 548
C+ C N G+C CLC PG G C + + P C +C+
Sbjct: 605 KHCRKKCNCANRGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQ 662
Query: 549 --DHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSD 606
D +G C C GF G C+ C G G C C +G C
Sbjct: 663 SCDKRDG-SCSCKAGFRGERCQAE--------CELGYFGPGCWQ-ACTCP---VGVACDS 709
Query: 607 QIDECYSSPCLNDGRCIDLVNGYQCN--CQPGTSGVNCEINFDDCASNPCIHGICMDGIN 664
EC RC G C C GT GVNC + C PC HG+
Sbjct: 710 VSGECGK-------RCPAGFQGEDCGQECPVGTFGVNCSSSCS-CGGAPC-HGVTGQ--- 757
Query: 665 RYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRC--ICPEGPHHPSCYSQVN 722
C C PG TG+ C D C G G C ICP H C +
Sbjct: 758 ---CRCPPGRTGEDCEAD--------------CPEGRWGLGCQEICPACQHAARCDPETG 800
Query: 723 ECLSNPCIHGNCTGGLSGYKC--LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780
CL C G G +C +C AGW G +C+ C C N G C
Sbjct: 801 ACL--------CLPGFVGSRCQDVCPAGWYGPSCQT---RC---SCANDGHCHPATG--H 844
Query: 781 CTCKKGFKGYNCQVNID------ECASNPC---LNQGTCFDDISGYTCHCVLPYTGKNCQ 831
C+C G+ G++CQ D +C S+PC G+C D ISG C C Y G C+
Sbjct: 845 CSCAPGWTGFSCQRACDTGHWGPDC-SHPCNCSAGHGSC-DAISGL-CLCEAGYVGPRCE 901
Query: 832 TVLAPCSPNP-CENAAVCKESPNFE--SYTCLCAPGWQGQRCT-------IDIDECISKP 881
P CE C+ + S C C GW+G C +D +
Sbjct: 902 QQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACN 961
Query: 882 CMNHGLCHNTQGSYMCECPPGFSGMDCEEDID------DCL-ANPCQNGGSCMDGVNTFS 934
C C GS C CP G G C E +C A C NG SC D V+
Sbjct: 962 CTAGAACDAVNGS--CLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC-DPVHG-Q 1017
Query: 935 CLCLPGFTGDKC----------QTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHC 984
C C PG+ G C + CL C+NGGTC D V+ + C C G+ G+ C
Sbjct: 1018 CHCAPGWMGPSCLQACPAGLYGDNCRHSCL---CQNGGTC-DPVSGH-CACPEGWAGLAC 1072
Query: 985 ENNINE------CTESS-CFNGGTCVDGINSFSCLCPVGFTGSFCLHE-INECSSHPCLN 1036
E C S C NGG C ++ CLCP G+TG C + C
Sbjct: 1073 EKECLPRDVRAGCRHSGGCLNGGLCDP--HTGRCLCPAGWTGDKCQSPCLRGWFGEACAQ 1130
Query: 1037 EGTCVDGLGTYR----CSCPLGYTGKNCQTLVNLCS-RSPCKNKGTCVQKK-----AESQ 1086
+C G + C CP G+TG C+ S C C + A
Sbjct: 1131 RCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGT 1190
Query: 1087 CLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGN----THYCQCPLGYT 1142
C C +G+ G C R G E LC C+N G+ T C+CP G+
Sbjct: 1191 CSCAAGYHGPSCQQR-----CPPGRYGPGCEQLCG----CLNGGSCDAATGACRCPTGFL 1241
Query: 1143 GSYCEEQLDECASNP-------CQHGATCSDFIGGYRCECVPGYQGVNCEYEVDE----- 1190
G+ C + P C GA C G C C PG GV CE +
Sbjct: 1242 GTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG--TCLCPPGRAGVRCERGCPQNRFGV 1299
Query: 1191 -CQNQ-PCQNGGTCID-----------LVNHFKCSCPPGTRGLLCEENIDDCARGPHCLN 1237
C++ C+NGG C H + +CPPG G C +C+ C N
Sbjct: 1300 GCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHL---ECS----CHN 1352
Query: 1238 GGQCMDRIGGYSCRCLPGFAGERCE-----GDINECLSNPCSSEGSLDCIQLTNDYLCVC 1292
C G +CRC PGF G+ CE G C + C ++ C+C
Sbjct: 1353 NSTCEPATG--TCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGR--CLC 1408
Query: 1293 RSAFTGRHCE------TFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
+ F G CE +F + C Q +GG A P +C CPPG SGA C
Sbjct: 1409 PAGFHGHFCERGCEPGSFGEGCHQRCDCDGG----APCDPVTGLCLCPPGRSGATC---- 1460
Query: 1347 GQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCH 1390
+ CR+G+ GP C DC G P G CH
Sbjct: 1461 -NLDCRRGQ------FGPSCTLHC--DCGGGADCDPV--SGQCH 1493
Score = 385 bits (989), Expect = e-106
Identities = 415/1483 (27%), Positives = 543/1483 (36%), Gaps = 369/1483 (24%)
Query: 221 LYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGV---CVD 277
L C+ S C +GG C C+C PGF+G C+ ++D+C H NGG CV+
Sbjct: 124 LSAECSASLCFHGGRC--VPGSAQPCHCPPGFQGPRCQYDVDECRTH---NGGCQHRCVN 178
Query: 278 GVNTYNCRCPPQW---TGQFCTEDVDECLLQPNACQNG---------------------- 312
+Y C C P + T ++ C L CQ+
Sbjct: 179 TPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQED 238
Query: 313 -------GTCANRNGG--YGCVCVNGWSGDDCS------------ENIDDCA--FASCTP 349
CANRNG + C V G + +C E++D+CA A C
Sbjct: 239 GRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAH 298
Query: 350 GSTCIDRVASFSCMCPEGKA----GLLCHLDDACISNPCHK---GALCDTNPLNGQYICT 402
G C++ SF C+C G G C+ + I N C G + + +CT
Sbjct: 299 G--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCT 356
Query: 403 CPQGYKGADCTE----DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA----GPRCE 454
CP+GY+ D + DVD+CA +S C+ C N G + C C GY G CE
Sbjct: 357 CPRGYE-LDTDQRTCIDVDDCA--DSPCCQQV--CTNNPGGYECGCYAGYRLSADGCGCE 411
Query: 455 MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVN-NGQC---- 509
D++EC S + C + G F C C G++ +H + P V+ +G+
Sbjct: 412 -DVDECASSRGGCEHHCTNLAGSFQCSCEAGYR-LHEDRRGCSPLEEPMVDLDGELPFVR 469
Query: 510 -VDKVNRFQCLCPPGFTGP---------------------VCQIDI--DDCSST--PCLN 543
+ + Q P F VC D DCS T C N
Sbjct: 470 PLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRN 529
Query: 544 GAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDP----CHHG-QCQDG--IDSYT--CI 594
G C+ +G C C G+TG++C E C PD C CQ+G DS T C
Sbjct: 530 GGTCLLGLDG--CDCPEGWTGLICNE---TCPPDTFGKNCSFSCSCQNGGTCDSVTGACR 584
Query: 595 CNPGYMGAICSDQIDECY-------SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFD 647
C PG G C D + Y C N GRC L C C PG G C +
Sbjct: 585 CPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA--CLCDPGLYGRFCHLTCP 642
Query: 648 DCASNPCIHGICM------------DGINRYSCVCSPGFTGQRCNIDIDECASNP-CRKG 694
A P C DG SC C GF G+RC + + P C +
Sbjct: 643 PWAFGPGCSEECQCVQPHTQSCDKRDG----SCSCKAGFRGERCQAECELGYFGPGCWQA 698
Query: 695 ATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC--LCDAGWVGI 752
TC GV +C S EC C G G C C G G+
Sbjct: 699 CTCPVGV--------------ACDSVSGEC------GKRCPAGFQGEDCGQECPVGTFGV 738
Query: 753 NCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDE------CAS--NPC 804
NC S+ C GG + V G +C C G G +C+ + E C C
Sbjct: 739 NC--------SSSCSCGGAPCHGVTG-QCRCPPGRTGEDCEADCPEGRWGLGCQEICPAC 789
Query: 805 LNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNP-CENAAVCKESPNFESYT--CLC 861
+ C D C C+ + G CQ V P C+ C + T C C
Sbjct: 790 QHAARC--DPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSC 847
Query: 862 APGWQGQRCTIDID------ECISKPC---MNHGLCHNTQGSYMCE-----------CPP 901
APGW G C D +C S PC HG C G +CE CP
Sbjct: 848 APGWTGFSCQRACDTGHWGPDC-SHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQ 906
Query: 902 GFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMN------ECLS 955
G G CE+ CQ+G +C D V+ +C C G+ G C+ +C S
Sbjct: 907 GHFGPGCEQRCQ------CQHGAAC-DHVSG-ACTCPAGWRGTFCEHACPAGFFGLDCRS 958
Query: 956 EPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI------NECTES-SCFNGGT------- 1001
G D VN +C C AG G C + C+++ +CFNG +
Sbjct: 959 ACNCTAGAACDAVNG-SCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQ 1017
Query: 1002 --CVDGINSFSCL--CPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTG 1057
C G SCL CP G G C H S C N GTC G C+CP G+ G
Sbjct: 1018 CHCAPGWMGPSCLQACPAGLYGDNCRH------SCLCQNGGTCDPVSG--HCACPEGWAG 1069
Query: 1058 KNCQ-TLVNLCSRSPCKNKGTCVQ----KKAESQCLCPSGWAGAYCDVPNVSCDIAASRR 1112
C+ + R+ C++ G C+ +CLCP+GW G C P + R
Sbjct: 1070 LACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCL--------R 1121
Query: 1113 GVLVEHLCQHSGVCINAGNTHY---CQCPLGYTGSYCEE------------QLDEC-ASN 1156
G E Q A H C+CP G+TGS CE+ Q+ +C N
Sbjct: 1122 GWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGEN 1181
Query: 1157 PCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQP-------CQNGGTCIDLVNHF 1209
P H AT + C C GY G +C+ + P C NGG+C
Sbjct: 1182 PACHPATGT-------CSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATG-- 1232
Query: 1210 KCSCPPGTRGLLCEENIDDCARGPHCLN-----GGQCMDRIGGYSCRCLPGFAGERCE-- 1262
C CP G G C GP+C + G D + G +C C PG AG RCE
Sbjct: 1233 ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG-TCLCPPGRAGVRCERG 1291
Query: 1263 ---GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCP---------- 1309
+ CS C ++ C C +TGRHCE CP
Sbjct: 1292 CPQNRFGVGCEHTCSCRNGGLC--HASNGSCSCGLGWTGRHCEL---ACPPGRYGAACHL 1346
Query: 1310 QMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSC----------GQVKCRKGEQCVH 1359
+ C N TC A+ CRC PGF G C+ C G C+ G C
Sbjct: 1347 ECSCHNNSTCEPATG-----TCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPC-D 1400
Query: 1360 TASGPRCFCPS---PRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE---- 1412
SG RC CP+ CE GC P G CH + C C G+ C+
Sbjct: 1401 PISG-RCLCPAGFHGHFCERGC--EPGSFGEGCHQR-------CDCD---GGAPCDPVTG 1447
Query: 1413 LYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDC 1455
L PP ATC R G +C H G DC
Sbjct: 1448 LCLCPPGRSGATCNLD-----CRRGQFGPSCTLHCDCGGGADC 1485
Score = 365 bits (937), Expect = e-100
Identities = 389/1404 (27%), Positives = 494/1404 (35%), Gaps = 368/1404 (26%)
Query: 24 HALQCRDGYE------------PCVNE-GMCV---TYHNGTGYCKCPEGFL----GEYCQ 63
H QCR G++ PC N G C+ G C+C G+ G+ C+
Sbjct: 225 HRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE 284
Query: 64 HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFT----GEDCQYSTSHPCFVSRPCLNGG 119
D C Q C+ G C C +G+ G C Y S NGG
Sbjct: 285 DVDECAAGLAQCAHGCLNTQ--GSFKCVCHAGYELGADGRQC-YRIEMEIVNSCEANNGG 341
Query: 120 TCHMLSRDTYE--CTCQVGFT----GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTG 173
H S + CTC G+ + C D C PC CT + C C G
Sbjct: 342 CSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYECGCYAG 400
Query: 174 FT----GQKCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSLYVP 224
+ G CE DV+EC G C+H C NL GS+QC C G+ + C L P
Sbjct: 401 YRLSADGCGCE-DVDECASSRGGCEHH--CTNLAGSFQCSCEAGYRLHEDRRGCSPLEEP 457
Query: 225 CA----------PSPCV--------------------NGGTCRQTGDFTFECNCLPGFEG 254
P P + R T + CL G
Sbjct: 458 MVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFG 517
Query: 255 STCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPN-----AC 309
C DDC +NGG C+ G++ C CP WTG C E N +C
Sbjct: 518 HDCSLTCDDC-----RNGGTCLLGLD--GCDCPEGWTGLICNETCPPDTFGKNCSFSCSC 570
Query: 310 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFAS-CTPGSTCIDRVASF----SCMC 364
QNGGTC + G C C G SG +C + + C C +R +C+C
Sbjct: 571 QNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLC 628
Query: 365 PEGKAGLLCHL----------------------------DDACISNPCHKGALCDTNPLN 396
G G CHL D +C +G C
Sbjct: 629 DPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECEL 688
Query: 397 GQY------ICTCP-----------------QGYKGADCTED--VDECAMANSNPCEHAG 431
G + CTCP G++G DC ++ V + S+ C G
Sbjct: 689 GYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGG 748
Query: 432 K-CVNTDGAFHCECLKGYAGPRCEMDINE------CHS--DPCQNDATCLDKIGGFTCLC 482
C G C C G G CE D E C CQ+ A C + G CLC
Sbjct: 749 APCHGVTG--QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLC 804
Query: 483 MPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCL 542
+PGF G C Q +CP G+ GP CQ CS C
Sbjct: 805 LPGFVGSRC-------------------------QDVCPAGWYGPSCQTR---CS---CA 833
Query: 543 NGAKCIDHPNGYECQCATGFTGVLCEENID--NCDPD---PCH----HGQCQDGIDSYTC 593
N C HP C CA G+TG C+ D + PD PC+ HG C D I S C
Sbjct: 834 NDGHC--HPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSC-DAI-SGLC 889
Query: 594 ICNPGYMGAICSDQIDECYSSP-------CLNDGRCIDLVNGYQCNCQPGTSGVNCE--- 643
+C GY+G C Q + + P C + C D V+G C C G G CE
Sbjct: 890 LCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAAC-DHVSG-ACTCPAGWRGTFCEHAC 947
Query: 644 ----INFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNP----CRKGA 695
D ++ C G D +N SC+C G G RC + C ++ C +
Sbjct: 948 PAGFFGLDCRSACNCTAGAACDAVNG-SCLCPAGRRGPRC---AETCPAHTYGHNCSQAC 1003
Query: 696 TCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCL--CDAGWVGIN 753
C NG + C P H C+ C G G CL C AG G N
Sbjct: 1004 ACFNGAS-----CD--PVHGQCH---------------CAPGWMGPSCLQACPAGLYGDN 1041
Query: 754 CEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECA----------SNP 803
C ++ CL CQNGGTCD V+G+ C C +G+ G C+ EC S
Sbjct: 1042 C---RHSCL---CQNGGTCDP-VSGH-CACPEGWAGLACE---KECLPRDVRAGCRHSGG 1090
Query: 804 CLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN----PCENAAVCKESPNFESYT- 858
CLN G C D +G C C +TG CQ+ PC C C T
Sbjct: 1091 CLNGGLC-DPHTG-RCLCPAGWTGDKCQS---PCLRGWFGEACAQRCSCPPGAACHHVTG 1145
Query: 859 -CLCAPGWQGQRCTI-----DIDECISKPCMNHG---LCHNTQGSYMCECPPGFSGMDCE 909
C C PG+ G C E ++ C G CH G+ C C G+ G C+
Sbjct: 1146 ACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGT--CSCAAGYHGPSCQ 1203
Query: 910 EDIDDCLANP-------CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEP----- 957
+ P C NGGSC T +C C GF G C + P
Sbjct: 1204 QRCPPGRYGPGCEQLCGCLNGGSC--DAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHV 1261
Query: 958 --CKNGGTCSDYVNSYTCKCQAGFDGVHCENNINE------CTES-SCFNGGTCVDGINS 1008
C G C TC C G GV CE + C + SC NGG C ++
Sbjct: 1262 CGCGQGAACDPVTG--TCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLC--HASN 1317
Query: 1009 FSCLCPVGFTGSFCLHEIN----------ECSSHPCLNEGTCVDGLGTYRCS-------- 1050
SC C +G+TG C ECS H N TC GT RC
Sbjct: 1318 GSCSCGLGWTGRHCELACPPGRYGAACHLECSCH---NNSTCEPATGTCRCGPGFYGQAC 1374
Query: 1051 ---CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDI 1107
CP G+ G CQ L +PC +CLCP+G+ G +C+ C+
Sbjct: 1375 EHPCPPGFHGAGCQGLCWCQHGAPCD--------PISGRCLCPAGFHGHFCER---GCEP 1423
Query: 1108 AASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNP-------CQH 1160
+ G C C T C CP G +G+ C P C
Sbjct: 1424 GSFGEGCHQRCDCDGGAPCDPV--TGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGG 1481
Query: 1161 GATCSDFIGGYRCECVPGYQGVNC 1184
GA C G +C CV GY G C
Sbjct: 1482 GADCDPVSG--QCHCVDGYMGPTC 1503
Score = 341 bits (875), Expect = 5e-93
Identities = 349/1286 (27%), Positives = 484/1286 (37%), Gaps = 301/1286 (23%)
Query: 375 LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCV 434
L C ++ C G C C CP G++G C DVDEC N C+H +CV
Sbjct: 124 LSAECSASLCFHGGRCVPGSAQP---CHCPPGFQGPRCQYDVDECRTHNGG-CQH--RCV 177
Query: 435 NTDGAFHCECLKGY---AGPRCEMDINECH--SDPCQNDATCLDKIGGFTCLCMPGFK-- 487
NT G++ CEC G+ R + IN C + CQ+ L I C C PGF+
Sbjct: 178 NTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLT-ITRHRCQCRPGFQLQ 236
Query: 488 --GVHCELEINECQSNPCVN-NGQCVDKVNRFQ----CLCPPGFT----GPVCQIDIDDC 536
G HC + +PC N NG C+ + + C C G+ G C+ D+D+C
Sbjct: 237 EDGRHC------VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDEC 289
Query: 537 SS--TPCLNGAKCIDHPNGYECQCATGFT----GVLCE----ENIDNCDPDP--CHHGQC 584
++ C +G C++ ++C C G+ G C E +++C+ + C HG C
Sbjct: 290 AAGLAQCAHG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-C 346
Query: 585 QDGIDSYTCICNPGYMGAICSDQ-----IDECYSSPCLNDGRCIDLVNGYQCNCQPG--- 636
C C GY + +DQ +D+C SPC C + GY+C C G
Sbjct: 347 SHTSAGPLCTCPRGY--ELDTDQRTCIDVDDCADSPCCQQV-CTNNPGGYECGCYAGYRL 403
Query: 637 -TSGVNCEINFDDCASNP--CIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRK 693
G CE + D+CAS+ C H C + + C C G+ + D +P +
Sbjct: 404 SADGCGCE-DVDECASSRGGCEHH-CTNLAGSFQCSCEAGY-----RLHEDRRGCSPLEE 456
Query: 694 GATCINGVNGF----------------------------------------RCICPEGPH 713
++G F + +C +
Sbjct: 457 PMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSF 516
Query: 714 HPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCE-------VDKNECLSNPC 766
C ++C + G C GL G C C GW G+ C KN S C
Sbjct: 517 GHDCSLTCDDCRNG----GTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSFSCSC 570
Query: 767 QNGGTCDNLVNGYRCT-----------CKKGFKGYNCQVNIDECASNPCLNQGTCFDDIS 815
QNGGTCD++ RC C KG+ G +C+ + C N+G C
Sbjct: 571 QNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCN------CANRGRCHRLYG 624
Query: 816 GYTCHCVLPYTGKNCQTVLAPCSPNP-CENAAVCKESPNFESY-----TCLCAPGWQGQR 869
C C G+ C P + P C C + P+ +S +C C G++G+R
Sbjct: 625 A--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQ-PHTQSCDKRDGSCSCKAGFRGER 681
Query: 870 CTIDIDECISKP-------CMNHGLCHNTQGSYMCECPPGFSGMDCEEDID------DCL 916
C + + P C C + G CP GF G DC ++ +C
Sbjct: 682 CQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNC- 740
Query: 917 ANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQ 976
++ C GG+ GV T C C PG TG+ C+ D E + G C + C
Sbjct: 741 SSSCSCGGAPCHGV-TGQCRCPPGRTGEDCEADCPEG-----RWGLGCQEI-------CP 787
Query: 977 AGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLN 1036
A C+ C F G C D +CP G+ G C CS C N
Sbjct: 788 ACQHAARCDPETGACLCLPGFVGSRCQD-------VCPAGWYGPSCQ---TRCS---CAN 834
Query: 1037 EGTCVDGLGTYRCSCPLGYTGKNCQTLVNL------CSRSPCK---NKGTCVQKKAESQC 1087
+G C G CSC G+TG +CQ + CS PC G+C C
Sbjct: 835 DGHCHPATG--HCSCAPGWTGFSCQRACDTGHWGPDCSH-PCNCSAGHGSC--DAISGLC 889
Query: 1088 LCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCE 1147
LC +G+ G C+ C G CQH C + C CP G+ G++CE
Sbjct: 890 LCEAGYVGPRCEQ---QCPQGHFGPGCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCE 944
Query: 1148 EQ-------LDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE-------YEVDECQN 1193
LD ++ C GA C D + G C C G +G C Y + Q
Sbjct: 945 HACPAGFFGLDCRSACNCTAGAAC-DAVNG-SCLCPAGRRGPRCAETCPAHTYGHNCSQA 1002
Query: 1194 QPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENI------DDCARGPHCLNGGQCMDRIGG 1247
C NG +C + H +C C PG G C + D+C C NGG C D + G
Sbjct: 1003 CACFNGASCDPV--HGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC-DPVSG 1059
Query: 1248 YSCRCLPGFAGERCEGDINECL----------SNPCSSEGSLDCIQLTNDYLCVCRSAFT 1297
+ C C G+AG CE ECL S C + G D + C+C + +T
Sbjct: 1060 H-CACPEGWAGLACE---KECLPRDVRAGCRHSGGCLNGGLCD----PHTGRCLCPAGWT 1111
Query: 1298 GRHCETFVDVCPQMPCLNGG---TCAVASNMPDGFIC-------RCPPGFSGARCQSSCG 1347
G C Q PCL G CA + P G C RCPPGF+G+ C+ +C
Sbjct: 1112 GDKC--------QSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACP 1163
Query: 1348 QVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFS 1407
GE C C CP +CHP +C CA +
Sbjct: 1164 PGSF--GEDCAQ-----MCQCPG--------------ENPACHPATG----TCSCAAGYH 1198
Query: 1408 GSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQ--WDGGDCSLTMENP--W 1463
G C+ PP C Q C G CD A + C + G DC+LT
Sbjct: 1199 GPSCQ-QRCPPGRYGPGC-EQLCG-CLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFG 1255
Query: 1464 ANCSSPLPCWDYINNQCDELCNTVEC 1489
NC+ C CD + T C
Sbjct: 1256 PNCTHVCGCGQ--GAACDPVTGTCLC 1279
Score = 282 bits (721), Expect = 3e-75
Identities = 306/1119 (27%), Positives = 402/1119 (35%), Gaps = 255/1119 (22%)
Query: 19 CAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCE---KN---- 71
C + C + C N G C+ +G C CPEG+ G C P + KN
Sbjct: 511 CLDDSFGHDCSLTCDDCRNGGTCLLGLDG---CDCPEGWTGLICNETCPPDTFGKNCSFS 567
Query: 72 -RCQNGGTCVAQAMLGKATCRCASGFTGEDCQ------YSTSHPCFVSRPCLNGGTCHML 124
CQNGGTC + CRC G +G +C+ Y H C C N G CH L
Sbjct: 568 CSCQNGGTCDSVT----GACRCPPGVSGTNCEDGCPKGYYGKH-CRKKCNCANRGRCHRL 622
Query: 125 SRDTYECTCQVGFTGKECQWT-------DACLSH-PCANGSTCTTVANQFSCKCLTGFTG 176
C C G G+ C T C C T + SC C GF G
Sbjct: 623 YG---ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRG 679
Query: 177 QKCETDVNECDI----PG-----HCQHGGTCLNLPGSYQCQCPQGFTGQYC------DSL 221
++C+ EC++ PG C G C ++ G +CP GF G+ C +
Sbjct: 680 ERCQA---ECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTF 736
Query: 222 YVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR-----------CQ 270
V C+ S G C T +C C PG G CE DCP R CQ
Sbjct: 737 GVNCSSSCSCGGAPCH---GVTGQCRCPPGRTGEDCEA---DCPEGRWGLGCQEICPACQ 790
Query: 271 NGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGY----GCVC 326
+ C T C C P + G C +DV +CQ +CAN + C C
Sbjct: 791 HAARC--DPETGACLCLPGFVGSRC-QDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSC 847
Query: 327 VNGWSGDDCSENID------DCAF-ASCTPGSTCIDRVASFSCMCPEGKAGLLC------ 373
GW+G C D DC+ +C+ G D ++ C+C G G C
Sbjct: 848 APGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGL-CLCEAGYVGPRCEQQCPQ 906
Query: 374 -HLDDACISN-PCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD------ECAMANSN 425
H C C GA CD + CTCP G++G C +C A +
Sbjct: 907 GHFGPGCEQRCQCQHGAACD----HVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACN- 961
Query: 426 PCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-------NECHSDPCQNDATCLDKIGGF 478
C C +G+ C C G GPRC N + C N A+C D + G
Sbjct: 962 -CTAGAACDAVNGS--CLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC-DPVHG- 1016
Query: 479 TCLCMPGFKGVHC------ELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQ-- 530
C C PG+ G C L + C+ + NG D V+ C CP G+ G C+
Sbjct: 1017 QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSG-HCACPEGWAGLACEKE 1075
Query: 531 -----IDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQ 585
+ S CLNG C H C C G+TG C+ PC G
Sbjct: 1076 CLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQ--------SPCLRGWFG 1125
Query: 586 DGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEIN 645
+ + C C P GA C C P C + C PG+ G +C
Sbjct: 1126 EAC-AQRCSCPP---GAACHHVTGACRCPPGFTGSGC-------EQACPPGSFGEDCAQM 1174
Query: 646 FDDCASNPCIHGI-----CMDGINRYSCV--CSPGFTGQRCNIDIDECASNPCRKGAT-- 696
NP H C G + SC C PG G C + C + AT
Sbjct: 1175 CQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCE-QLCGCLNGGSCDAATGA 1233
Query: 697 --CINGVNGFRC--ICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGI 752
C G G C CP+G P+C + C C G ++G CLC G G+
Sbjct: 1234 CRCPTGFLGTDCNLTCPQGRFGPNC---THVC---GCGQGAACDPVTG-TCLCPPGRAGV 1286
Query: 753 NCEVDKNECLSN----------PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNID----- 797
CE C N C+NGG C + NG C+C G+ G +C++
Sbjct: 1287 RCE---RGCPQNRFGVGCEHTCSCRNGGLC-HASNG-SCSCGLGWTGRHCELACPPGRYG 1341
Query: 798 -----ECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN----PCENAAVC 848
EC+ C N TC + +G TC C + G+ C+ PC P C+ C
Sbjct: 1342 AACHLECS---CHNNSTC-EPATG-TCRCGPGFYGQACE---HPCPPGFHGAGCQGLCWC 1393
Query: 849 KESPNFE--SYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGM 906
+ + S CLC G+ G C C PG G
Sbjct: 1394 QHGAPCDPISGRCLCPAGFHGHFCERG-------------------------CEPGSFGE 1428
Query: 907 DCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSD 966
C + D C G C D V T CLC PG +G C D C+ G
Sbjct: 1429 GCHQRCD------CDGGAPC-DPV-TGLCLCPPGRSGATCNLD--------CRRG----Q 1468
Query: 967 YVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDG 1005
+ S T C G G C+ +C + G TC +G
Sbjct: 1469 FGPSCTLHCDCG-GGADCDPVSGQCHCVDGYMGPTCREG 1506
Score = 217 bits (553), Expect = 1e-55
Identities = 243/931 (26%), Positives = 329/931 (35%), Gaps = 213/931 (22%)
Query: 712 PHHPSCYSQVNECLSNPCIHGN-CTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGG 770
P C S EC ++ C HG C G S C C G+ G C+ D +EC ++ NGG
Sbjct: 118 PDEEGCLSA--ECSASLCFHGGRCVPG-SAQPCHCPPGFQGPRCQYDVDECRTH---NGG 171
Query: 771 T---CDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCV-LPYT 826
C N Y C CK GF+ + S CL +C G HCV L T
Sbjct: 172 CQHRCVNTPGSYLCECKPGFRLHT--------DSRTCLAINSCALGNGGCQHHCVQLTIT 223
Query: 827 GKNCQTVLAPCSP--------------NPCENA-AVCKESPNFES--YTCLCAPGWQ--- 866
CQ C P +PC N C C C G+Q
Sbjct: 224 RHRCQ-----CRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAA 278
Query: 867 -GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEEDIDDCLANPCQ 921
G+ C D+DEC + C NTQGS+ C C G+ G C I+ + N C+
Sbjct: 279 DGKACE-DVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYR-IEMEIVNSCE 336
Query: 922 -NGGSCMDGVNTFS----CLCLPGF---TGDKCQTDMNECLSEPCKNGGTCSDYVNSYTC 973
N G C G + S C C G+ T + D+++C PC C++ Y C
Sbjct: 337 ANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYEC 395
Query: 974 KCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINE- 1028
C AG+ DG CE +++EC S C + SF C C G+ LHE
Sbjct: 396 GCYAGYRLSADGCGCE-DVDECASSRGGCEHHCTNLAGSFQCSCEAGYR----LHEDRRG 450
Query: 1029 CSS---------------HPCLNEGTCVDGLGTYRCSCPLG-------YTGKNCQTLVNL 1066
CS P + D L +G G++ T +
Sbjct: 451 CSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFV 510
Query: 1067 C-----------SRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVL 1115
C + C+N GTC+ C CP GW G C N +C +
Sbjct: 511 CLDDSFGHDCSLTCDDCRNGGTCL--LGLDGCDCPEGWTGLIC---NETCPPDTFGKNCS 565
Query: 1116 VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCEC 1175
CQ+ G C + T C+CP G +G+ CE+ C
Sbjct: 566 FSCSCQNGGTCDSV--TGACRCPPGVSGTNCED-------------------------GC 598
Query: 1176 VPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHC 1235
GY G +C + + C N G C L + C C PG G C A GP C
Sbjct: 599 PKGYYGKHCRKKCN------CANRGRCHRL--YGACLCDPGLYGRFCHLTCPPWAFGPGC 650
Query: 1236 LNGGQCM-------DRIGGYSCRCLPGFAGERCEGDINECLSNP-----CSSEGSLDCIQ 1283
QC+ D+ G SC C GF GERC+ + P C+ + C
Sbjct: 651 SEECQCVQPHTQSCDKRDG-SCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDS 709
Query: 1284 LTNDYLCVCRSAFTGRHC------ETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF 1337
++ + C + F G C TF C G C + CRCPPG
Sbjct: 710 VSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQ-----CRCPPGR 764
Query: 1338 SGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPY 1397
+G C++ C + + G Q + CP+ CQH C P+
Sbjct: 765 TGEDCEADCPEGRWGLGCQEI---------CPA------------CQHAARCDPETG--- 800
Query: 1398 YSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADK---ARDGVCDEACNSHACQ--WDG 1452
+C C P F GSRC+ PA C + A DG C A +C W G
Sbjct: 801 -ACLCLPGFVGSRCQ------DVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTG 853
Query: 1453 GDCSLTME-NPWA-NCSSPLPCWDYINNQCDELCNTVECL--FDNFECQGNSKTCKYDKY 1508
C + W +CS P C + CD + C + C+ +
Sbjct: 854 FSCQRACDTGHWGPDCSHPCNC-SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPG 912
Query: 1509 CADHFKDNH---CDQGCNSEEC--GWDGLDC 1534
C + H CD + C GW G C
Sbjct: 913 CEQRCQCQHGAACDHVSGACTCPAGWRGTFC 943
Score = 207 bits (528), Expect = 8e-53
Identities = 198/664 (29%), Positives = 249/664 (37%), Gaps = 147/664 (22%)
Query: 11 ALLALWLCCAA---PAHALQCRDGYEPCVNEGMCVTYHNG-----TGYCKCPEGFLGEYC 62
A+ L LC A P QC G+ E C H +G C CP G+ G +C
Sbjct: 884 AISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFC 943
Query: 63 QHRDPCE--KNRCQNGGTCVAQAMLG--KATCRCASGFTGEDCQ-----YSTSHPCFVSR 113
+H P C++ C A A +C C +G G C ++ H C +
Sbjct: 944 EHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQAC 1003
Query: 114 PCLNGGTCHMLSRDTYECTCQVGFTGKECQ-------WTDACL-SHPCANGSTCTTVANQ 165
C NG +C + +C C G+ G C + D C S C NG TC V+
Sbjct: 1004 ACFNGASCDPVHG---QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGH 1060
Query: 166 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLN----LPGSYQCQCPQGFTGQYCDSL 221
C C G+ G CE + D+ C+H G CLN P + +C CP G+TG C S
Sbjct: 1061 --CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQS- 1117
Query: 222 YVPCAPS----------PCVNGGTCRQTGDFTFECNCLPGFEGSTCERNI------DDCP 265
PC C G C T C C PGF GS CE+ +DC
Sbjct: 1118 --PCLRGWFGEACAQRCSCPPGAACHHV---TGACRCPPGFTGSGCEQACPPGSFGEDCA 1172
Query: 266 NHRCQNGG---VCVDGVNTYNC-----------RCPPQWTGQFCTEDVDECLLQPNACQN 311
CQ G C T +C RCPP G C Q C N
Sbjct: 1173 -QMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCE--------QLCGCLN 1223
Query: 312 GGTCANRNGGYGCVCVNGWSGDDCSENIDDCAF-------ASCTPGSTCIDRVASFSCMC 364
GG+C G C C G+ G DC+ F C G+ C D V +C+C
Sbjct: 1224 GGSCDAATG--ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC-DPVTG-TCLC 1279
Query: 365 PEGKAGLLCHLDDACISN----------PCHKGALCDTNPLNGQYIC-----------TC 403
P G+AG+ C + C N C G LC + NG C C
Sbjct: 1280 PPGRAGVRC--ERGCPQNRFGVGCEHTCSCRNGGLCHAS--NGSCSCGLGWTGRHCELAC 1335
Query: 404 PQGYKGADCTEDVDECAMANSNPCEHA-GKCVNTDGAF--HCE--CLKGYAGPRCEMDIN 458
P G GA C EC+ N++ CE A G C G + CE C G+ G C+
Sbjct: 1336 PPGRYGAACHL---ECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQ---G 1389
Query: 459 ECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINE------CQSNPCVNNGQCVDK 512
C CQ+ A C D I G CLC GF G CE C + G D
Sbjct: 1390 LCW---CQHGAPC-DPISG-RCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDP 1444
Query: 513 VNRFQCLCPPGFTGPVCQIDIDDCSSTP-------CLNGAKCIDHPNGYECQCATGFTGV 565
V CLCPPG +G C +D P C GA C P +C C G+ G
Sbjct: 1445 VTGL-CLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADC--DPVSGQCHCVDGYMGP 1501
Query: 566 LCEE 569
C E
Sbjct: 1502 TCRE 1505
Score = 105 bits (261), Expect = 7e-22
Identities = 121/494 (24%), Positives = 183/494 (37%), Gaps = 95/494 (19%)
Query: 1082 KAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY 1141
+A + C GW + +S + +AS LC H G C+ G+ C CP G+
Sbjct: 103 EARTVLRCCRGWMQQPDEEGCLSAECSAS--------LCFHGGRCV-PGSAQPCHCPPGF 153
Query: 1142 TGSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQ----GVNCEYEVDECQ--N 1193
G C+ +DEC ++ CQH C + G Y CEC PG++ C ++ C N
Sbjct: 154 QGPRCQYDVDECRTHNGGCQH--RCVNTPGSYLCECKPGFRLHTDSRTC-LAINSCALGN 210
Query: 1194 QPCQNGGTCIDL-VNHFKCSCPPGTRGLLCEENIDDCARGPHCLN-GGQCMDRI----GG 1247
CQ+ C+ L + +C C PG + +E+ C R C N G CM R G
Sbjct: 211 GGCQH--HCVQLTITRHRCQCRPGFQ---LQEDGRHCVRRSPCANRNGSCMHRCQVVRGL 265
Query: 1248 YSCRCLPGFA----GERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF----TGR 1299
C C G+ G+ CE D++EC + ++ + C+ + CVC + + GR
Sbjct: 266 ARCECHVGYQLAADGKACE-DVDECAAG--LAQCAHGCLNTQGSFKCVCHAGYELGADGR 322
Query: 1300 HCETF-VDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCV 1358
C +++ NGG S+ G +C CP G+ Q +C V
Sbjct: 323 QCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDV--------- 373
Query: 1359 HTASGPRCFCPSPRDCESGCASSPCQHGGSCHP--QRQPPYYSCQCAPPF--SGSRCELY 1414
CA SPC C P Y C C + S C
Sbjct: 374 -----------------DDCADSPC-----CQQVCTNNPGGYECGCYAGYRLSADGCGCE 411
Query: 1415 TAPPSTPPATCLSQYCADKARDGVCDEACNS-HACQWDGGDCSLTMENPWANCSS----- 1468
+C + A C +C + + D CS +E P +
Sbjct: 412 DVDECASSRGGCEHHCTNLAGSFQC--SCEAGYRLHEDRRGCS-PLEEPMVDLDGELPFV 468
Query: 1469 -PLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKY-CADHFKDNHCDQGC---- 1522
PLP + ++ +L + D E + + +K+ C D + C C
Sbjct: 469 RPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCR 528
Query: 1523 NSEEC--GWDGLDC 1534
N C G DG DC
Sbjct: 529 NGGTCLLGLDGCDC 542
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 366 bits (940), Expect = e-100
Identities = 173/465 (37%), Positives = 234/465 (50%), Gaps = 43/465 (9%)
Query: 792 CQVNIDECASNPCLNQGTCFDDISGYTCHC--VLPYTGKNCQTVLAPCSPNPCENAAVCK 849
C N C SN C N TC D C C K+C + PC NPC+ +A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 850 ESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE 909
+P S+ C C PG+ G C I C C + G+CH +C CP G++G CE
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 910 EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVN 969
D D+C ++PCQNG C DG++ +SC C+PG+ G C +++EC S+PCKN TC + +
Sbjct: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
Query: 970 SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINEC 1029
YTC C + GV+CE I+EC C NG TC D + ++ C C GF G C +EC
Sbjct: 207 RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC 266
Query: 1030 SSHPCLNEGTCVDGLGTYRCSCP-LGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCL 1088
+S PCL+ G CVDG Y C+C G+TG +C+TL+ LC PC N TC C
Sbjct: 267 ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCH 326
Query: 1089 CPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCI--------------------N 1128
C G+ GA C++ C+ + CQ +G C+ +
Sbjct: 327 CWPGYTGAQCEIDLNECN----------SNPCQSNGECVELSSEKQYGRITGLPSSFSYH 376
Query: 1129 AGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV------PGYQGV 1182
+ + C C G+TG +CEE ++EC+SNPCQ+G TC + G Y C C Y G
Sbjct: 377 EASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGR 436
Query: 1183 NCEYEVDECQNQPCQNGGTCI----DLVNHFKCSCPPGTRGLLCE 1223
+C + C +Q C N GTCI D + F C CP G G LCE
Sbjct: 437 DCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 364 bits (934), Expect = e-100
Identities = 174/462 (37%), Positives = 243/462 (52%), Gaps = 39/462 (8%)
Query: 642 CEINFDDCASNPCIHG-ICMDGINRYSCVCSPGFTG--QRCNIDIDECASNPCRKGATCI 698
C N C SN C + C D C CS + C+ D C SNPC+ ATC+
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 699 N--GVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYK-CLCDAGWVGINCE 755
N G F C CP G C + + C N C HG Y C+C AG+ G CE
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 756 VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDIS 815
+D +EC S+PCQNG C + ++GY C C G++G +C + +DECAS+PC N+ TC ++I
Sbjct: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
Query: 816 GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDID 875
YTC C Y+G NC+ + C PC N A C+++ +Y C CAPG+ G C ++ D
Sbjct: 207 RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDA--LGAYFCDCAPGFLGDHCELNTD 264
Query: 876 ECISKPCMNHGLCHNTQGSYMCECP-PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS 934
EC S+PC++ GLC + + Y C C GF+G CE + C + PC N +C D V+ ++
Sbjct: 265 ECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYT 324
Query: 935 CLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDY--------------------VNSYTCK 974
C C PG+TG +C+ D+NEC S PC++ G C + + Y C
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 975 CQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG------FTGSFCLHEINE 1028
CQ GF G+HCE ++NEC+ + C NGGTC + +++C CP + G C +
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 1029 CSSHPCLNEGTCV----DGLGTYRCSCPLGYTGKNCQTLVNL 1066
C+ CLN GTC+ DG + C CP GYTG C+ L
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 364 bits (934), Expect = e-100
Identities = 176/458 (38%), Positives = 243/458 (53%), Gaps = 38/458 (8%)
Query: 679 CNIDIDECASNPCRKGATCINGVNGFRCICPEGPHH--PSCYSQVNECLSNPCI-HGNC- 734
CN + C SN C+ +TC + C C + ++ C + + C SNPC C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 735 -TGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ 793
T G + C C G+ G CE C N CQ+GG C C C G+ G C+
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 794 VNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPN 853
++ DECAS+PC N C D I GY+C CV Y G++C + C+ +PC+N A C
Sbjct: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNE-- 204
Query: 854 FESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDID 913
YTC+C + G C ++IDEC S+PC+N C + G+Y C+C PGF G CE + D
Sbjct: 205 IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTD 264
Query: 914 DCLANPCQNGGSCMDGVNTFSCLCL-PGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972
+C + PC +GG C+DG N +SC C GFTG C+T M C S+PC N TC D V++YT
Sbjct: 265 ECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYT 324
Query: 973 CKCQAGFDGVHCENNINECTESSCFNGGTCVD-----------GI-NSFS--------CL 1012
C C G+ G CE ++NEC + C + G CV+ G+ +SFS C+
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 1013 CPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLG------YTGKNCQTLVNL 1066
C GFTG C ++NECSS+PC N GTC + G Y C CP Y G++C ++
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 1067 CSRSPCKNKGTCVQKKAESQ----CLCPSGWAGAYCDV 1100
C+ C N GTC+ + Q CLCPSG+ G+ C++
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 361 bits (927), Expect = 4e-99
Identities = 174/459 (37%), Positives = 236/459 (51%), Gaps = 40/459 (8%)
Query: 335 CSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGL---LCHLDDACISNPCHKGALCD 391
C++N C SC STC D C C + L ++ D C SNPC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 392 TNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGP 451
P ++C CP GY G C + C N C+H G C C C GYAG
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCG---KNSCQHGGICHQDPIYPVCICPAGYAGR 143
Query: 452 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVD 511
CE+D +EC S PCQN A C D I G++C C+PG++G HC+LE++EC S+PC N C++
Sbjct: 144 FCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLN 203
Query: 512 KVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI 571
++ R+ C+CP ++G C+++ID+C S PCLNGA C D Y C CA GF G CE N
Sbjct: 204 EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNT 263
Query: 572 DNCDPDPC-HHGQCQDGIDSYTCIC-NPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGY 629
D C PC H G C DG + Y+C C G+ G C + C+S PC N+ C D V+ Y
Sbjct: 264 DECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNY 323
Query: 630 QCNCQPGTSGVNCEINFDDCASNPC-IHGICMD--------------------GINRYSC 668
C+C PG +G CEI+ ++C SNPC +G C++ + Y C
Sbjct: 324 TCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVC 383
Query: 669 VCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYS--------- 719
+C PGFTG C D++EC+SNPC+ G TC N + C CP + Y
Sbjct: 384 ICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL 443
Query: 720 --QVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEV 756
+CL+N + G G+ CLC +G+ G CE+
Sbjct: 444 GCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 343 bits (879), Expect = 2e-93
Identities = 166/462 (35%), Positives = 233/462 (50%), Gaps = 44/462 (9%)
Query: 179 CETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTG--QYCDSLYVPCAPSPCVNGGTC 236
C + C + CQ+ TC + C C + CD++ PC +PC TC
Sbjct: 27 CNKNNTRC-LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATC 85
Query: 237 RQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
T G+ +F C C PG+ G+ CE I C + CQ+GG+C C CP + G+FC
Sbjct: 86 VNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC 145
Query: 296 TEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID 355
D DEC P CQNG C + GY C CV G+ G C +D+CA C +TC++
Sbjct: 146 EIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLN 203
Query: 356 RVASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTE 414
+ ++C+CP +G+ C L+ D C S PC GA C G Y C C G+ G C
Sbjct: 204 EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC--QDALGAYFCDCAPGFLGDHCEL 261
Query: 415 DVDECAMANSNPCEHAGKCVNTDGAFHCECL-KGYAGPRCEMDINECHSDPCQNDATCLD 473
+ DECA S PC H G CV+ + + C C G+ G CE + C S PC N+ATC D
Sbjct: 262 NTDECA---SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCED 318
Query: 474 KIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVD--------------------KV 513
+ +TC C PG+ G CE+++NEC SNPC +NG+CV+ +
Sbjct: 319 SVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEA 378
Query: 514 NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQC------ATGFTGVLC 567
+ + C+C PGFTG C+ D+++CSS PC NG C + P Y C C T + G C
Sbjct: 379 SGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDC 438
Query: 568 EENIDNCDPDPC-HHGQC----QDGIDSYTCICNPGYMGAIC 604
+ + C C ++G C QDG ++C+C GY G++C
Sbjct: 439 SDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 328 bits (841), Expect = 4e-89
Identities = 173/467 (37%), Positives = 234/467 (50%), Gaps = 45/467 (9%)
Query: 253 EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTG--QFCTEDVDECLLQPNACQ 310
+ S C +N C ++ CQN C D +C C + C D C P CQ
Sbjct: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP--CQ 80
Query: 311 NGGTCANRNG--GYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGK 368
TC N G + C C G+SG C I C SC G C C+CP G
Sbjct: 81 GSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGY 140
Query: 369 AGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPC 427
AG C +D D C S+PC GA+C + ++G Y C C GY+G C +VDECA S+PC
Sbjct: 141 AGRFCEIDHDECASSPCQNGAVCQ-DGIDG-YSCFCVPGYQGRHCDLEVDECA---SDPC 195
Query: 428 EHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK 487
++ C+N G + C C Y+G CE++I+EC S PC N ATC D +G + C C PGF
Sbjct: 196 KNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL 255
Query: 488 GVHCELEINECQSNPCVNNGQCVDKVNRFQCLCP-PGFTGPVCQIDIDDCSSTPCLNGAK 546
G HCEL +EC S PC++ G CVD NR+ C C GFTG C+ + C S PC N A
Sbjct: 256 GDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNAT 315
Query: 547 CIDHPNGYECQCATGFTGVLCEENIDNCDPDPCH-HGQCQD-----------GIDS---- 590
C D + Y C C G+TG CE +++ C+ +PC +G+C + G+ S
Sbjct: 316 CEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSY 375
Query: 591 -----YTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNC------QPGTSG 639
Y CIC PG+ G C + ++EC S+PC N G C +L Y C+C + G
Sbjct: 376 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGG 435
Query: 640 VNCEINFDDCASNPCI-HGICM----DGINRYSCVCSPGFTGQRCNI 681
+C C C+ +G C+ DG + +SC+C G+TG C I
Sbjct: 436 RDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 326 bits (836), Expect = 2e-88
Identities = 162/468 (34%), Positives = 226/468 (48%), Gaps = 45/468 (9%)
Query: 908 CEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTG-DK-CQTDMNECLSEPCKNGGTCS 965
C ++ CL+N CQN +C D C C DK C + C S PC+ TC
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 966 DYVN--SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCL 1023
+ S+ CKC G+ G CE I C ++SC +GG C C+CP G+ G FC
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 1024 HEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKA 1083
+ +EC+S PC N C DG+ Y C C GY G++C V+ C+ PCKN+ TC+ +
Sbjct: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
Query: 1084 ESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG 1143
C+CP ++G C++ C C + C +A ++C C G+ G
Sbjct: 207 RYTCICPHNYSGVNCELEIDEC----------WSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECV-PGYQGVNCEYEVDECQNQPCQNGGTC 1202
+CE DECAS PC HG C D Y C C G+ G +CE + C ++PC N TC
Sbjct: 257 DHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATC 316
Query: 1203 IDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMD------------------- 1243
D V+++ C C PG G CE ++++C P C + G+C++
Sbjct: 317 EDSVDNYTCHCWPGYTGAQCEIDLNECNSNP-CQSNGECVELSSEKQYGRITGLPSSFSY 375
Query: 1244 -RIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVC------RSAF 1296
GY C C PGF G CE D+NEC SNPC + G+ C L +Y C C R+ +
Sbjct: 376 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGT--CENLPGNYTCHCPFDNLSRTFY 433
Query: 1297 TGRHCETFVDVCPQMPCLNGGTCAV-ASNMPDGFICRCPPGFSGARCQ 1343
GR C + C CLN GTC + GF C CP G++G+ C+
Sbjct: 434 GGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 312 bits (799), Expect = 3e-84
Identities = 163/471 (34%), Positives = 228/471 (48%), Gaps = 52/471 (11%)
Query: 984 CENNINECTESSCFNGGTCVDGINSFSCLCP--VGFTGSFCLHEINECSSHPCLNEGTCV 1041
C N C +SC N TC D C C C + + C S+PC TCV
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 1042 DGLG--TYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCD 1099
+ G ++ C CP GY+G C+T + C ++ C++ G C Q C+CP+G+AG +C+
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 1100 VPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQ 1159
+ + C + CQ+ VC + + + C C GY G +C+ ++DECAS+PC+
Sbjct: 147 IDHDECASSP----------CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 1160 HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRG 1219
+ ATC + IG Y C C Y GVNCE E+DEC +QPC NG TC D + + C C PG G
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 1220 LLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCL-PGFAGERCEGDINECLSNPCSSEGS 1278
CE N D+CA P CL+GG C+D YSC C GF G CE + C S PC + +
Sbjct: 257 DHCELNTDECASQP-CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNAT 315
Query: 1279 LDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASN---------MPD-- 1327
C ++Y C C +TG CE ++ C PC + G C S+ +P
Sbjct: 316 --CEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSF 373
Query: 1328 ------GFICRCPPGFSGARCQ---SSCGQVKCRKGEQCVHTASGPRCFCP--------- 1369
G++C C PGF+G C+ + C C+ G C + C CP
Sbjct: 374 SYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY 433
Query: 1370 SPRDCES---GCASSPCQHGGSCHPQRQPPY--YSCQCAPPFSGSRCELYT 1415
RDC GC C + G+C P Q +SC C ++GS CE+ T
Sbjct: 434 GGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIAT 484
Score = 311 bits (797), Expect = 5e-84
Identities = 164/429 (38%), Positives = 214/429 (49%), Gaps = 54/429 (12%)
Query: 1008 SFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCP--LGYTGKNCQTLVN 1065
SFS L + SFC C S+ C N TC D CSC K+C + +
Sbjct: 15 SFSLL--IYIKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKD 72
Query: 1066 LCSRSPCKNKGTCVQKKAESQ--CLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHS 1123
C +PC+ TCV E C CP G++G C+ SC ++ CQH
Sbjct: 73 PCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCG----------KNSCQHG 122
Query: 1124 GVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVN 1183
G+C C CP GY G +CE DECAS+PCQ+GA C D I GY C CVPGYQG +
Sbjct: 123 GICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRH 182
Query: 1184 CEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMD 1243
C+ EVDEC + PC+N TC++ + + C CP G+ CE ID+C P CLNG C D
Sbjct: 183 CDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQP-CLNGATCQD 241
Query: 1244 RIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCR-SAFTGRHCE 1302
+G Y C C PGF G+ CE + +EC S PC G C+ N Y C C S FTG HCE
Sbjct: 242 ALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL--CVDGENRYSCNCTGSGFTGTHCE 299
Query: 1303 TFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ---SSCGQVKCRKGEQCV- 1358
T + +C PC N TC + D + C C PG++GA+C+ + C C+ +CV
Sbjct: 300 TLMPLCWSKPCHNNATC---EDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVE 356
Query: 1359 -------------------HTASGPRCFCP---SPRDCE---SGCASSPCQHGGSCHPQR 1393
H ASG C C + CE + C+S+PCQ+GG+C +
Sbjct: 357 LSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTC--EN 414
Query: 1394 QPPYYSCQC 1402
P Y+C C
Sbjct: 415 LPGNYTCHC 423
Score = 295 bits (755), Expect = 4e-79
Identities = 160/458 (34%), Positives = 211/458 (46%), Gaps = 83/458 (18%)
Query: 148 CLSHPCANGSTC------------------------------------------TTVANQ 165
CLS+ C N STC T
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 166 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC 225
F CKC G++G CET + C CQHGG C P C CP G+ G++C+ + C
Sbjct: 94 FLCKCPPGYSGTICETTIGSCG-KNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDEC 152
Query: 226 APSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCR 285
A SPC NG C Q G + C C+PG++G C+ +D+C + C+N C++ + Y C
Sbjct: 153 ASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCI 211
Query: 286 CPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFA 345
CP ++G C ++DEC QP C NG TC + G Y C C G+ GD C N D+CA
Sbjct: 212 CPHNYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQ 269
Query: 346 SCTPGSTCIDRVASFSCMCP-EGKAGLLCH-LDDACISNPCHKGALCDTNPLNGQYICTC 403
C G C+D +SC C G G C L C S PCH A C+ + N Y C C
Sbjct: 270 PCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN--YTCHC 327
Query: 404 PQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG--------------AFH------CE 443
GY GA C D++EC NSNPC+ G+CV ++H C
Sbjct: 328 WPGYTGAQCEIDLNEC---NSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 444 CLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLC------MPGFKGVHCELEINE 497
C G+ G CE D+NEC S+PCQN TC + G +TC C + G C +
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 498 CQSNPCVNNGQCV----DKVNRFQCLCPPGFTGPVCQI 531
C C+NNG C+ D + F CLCP G+TG +C+I
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 259 bits (663), Expect = 2e-68
Identities = 149/459 (32%), Positives = 204/459 (44%), Gaps = 43/459 (9%)
Query: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTC-HMLSR 126
C N CQN TC + +C + +DC + PCF S PC TC +
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCD-NMKDPCF-SNPCQGSATCVNTPGE 91
Query: 127 DTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 185
++ C C G++G C+ T +C + C +G C C C G+ G+ CE D +E
Sbjct: 92 RSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE 151
Query: 186 CDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTC-RQTGDFTF 244
C CQ+G C + Y C C G+ G++CD CA PC N TC + G +T
Sbjct: 152 C-ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT- 209
Query: 245 ECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLL 304
C C + G CE ID+C + C NG C D + Y C C P + G C + DEC
Sbjct: 210 -CICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECAS 268
Query: 305 QPNACQNGGTCANRNGGYGCVCV-NGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCM 363
QP C +GG C + Y C C +G++G C + C C +TC D V +++C
Sbjct: 269 QP--CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCH 326
Query: 364 CPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQ------------------YICTCP 404
C G G C +D + C SNPC C Q Y+C C
Sbjct: 327 CWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQ 386
Query: 405 QGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC------LKGYAGPRCEMDIN 458
G+ G C EDV+EC +SNPC++ G C N G + C C Y G C +
Sbjct: 387 PGFTGIHCEEDVNEC---SSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL 443
Query: 459 ECHSDPCQNDATCL----DKIGGFTCLCMPGFKGVHCEL 493
C C N+ TC+ D GF+CLC G+ G CE+
Sbjct: 444 GCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 254 bits (650), Expect = 6e-67
Identities = 148/458 (32%), Positives = 208/458 (45%), Gaps = 51/458 (11%)
Query: 35 CVNEGMCVTYHNGTGYCKCPE--GFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCR 91
C N C + C C + L + C + +DPC N CQ TCV C+
Sbjct: 39 CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCK 97
Query: 92 CASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYE-CTCQVGFTGKECQWT-DACL 149
C G++G C+ +T C C +GG CH Y C C G+ G+ C+ D C
Sbjct: 98 CPPGYSGTICE-TTIGSCG-KNSCQHGGICHQ--DPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 150 SHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC 209
S PC NG+ C + +SC C+ G+ G+ C+ +V+EC C++ TCLN G Y C C
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC-ASDPCKNEATCLNEIGRYTCIC 212
Query: 210 PQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRC 269
P ++G C+ C PC+NG TC+ F C+C PGF G CE N D+C + C
Sbjct: 213 PHNYSGVNCELEIDECWSQPCLNGATCQDALGAYF-CDCAPGFLGDHCELNTDECASQPC 271
Query: 270 QNGGVCVDGVNTYNCRCPPQ-WTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVN 328
+GG+CVDG N Y+C C +TG C + C +P C N TC + Y C C
Sbjct: 272 LHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKP--CHNNATCEDSVDNYTCHCWP 329
Query: 329 GWSGDDCSENIDDCAFASCTPGSTCID--------------------RVASFSCMCPEGK 368
G++G C ++++C C C++ + + C+C G
Sbjct: 330 GYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF 389
Query: 369 AGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCP------QGYKGADCTEDVDECAM 421
G+ C D + C SNPC G C+ P G Y C CP Y G DC++ + C
Sbjct: 390 TGIHCEEDVNECSSNPCQNGGTCENLP--GNYTCHCPFDNLSRTFYGGRDCSDILLGC-- 445
Query: 422 ANSNPCEHAGKCVN--TDG--AFHCECLKGYAGPRCEM 455
C + G C+ DG F C C GY G CE+
Sbjct: 446 -THQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 216 bits (549), Expect = 3e-55
Identities = 132/469 (28%), Positives = 190/469 (40%), Gaps = 80/469 (17%)
Query: 1096 AYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCP--LGYTGSYCEEQLDEC 1153
++C+ N C + + CQ++ C + + C C C+ D C
Sbjct: 25 SFCNKNNTRC----------LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPC 74
Query: 1154 ASNPCQHGATCSDFIG--GYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKC 1211
SNPCQ ATC + G + C+C PGY G CE + C CQ+GG C + C
Sbjct: 75 FSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVC 134
Query: 1212 SCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSN 1271
CP G G CE + D+CA P C NG C D I GYSC C+PG+ G C+ +++EC S+
Sbjct: 135 ICPAGYAGRFCEIDHDECASSP-CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASD 193
Query: 1272 PCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFIC 1331
PC +E + C+ Y C+C ++G +CE +D C PCLNG TC A + C
Sbjct: 194 PCKNEAT--CLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALG---AYFC 248
Query: 1332 RCPPGFSGARCQ---SSCGQVKCRKGEQCVHTASGPRCFCPSP----RDCESG---CASS 1381
C PGF G C+ C C G CV + C C CE+ C S
Sbjct: 249 DCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSK 308
Query: 1382 PCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDE 1441
PC + +C + Y+C C P ++G++CE+
Sbjct: 309 PCHNNATC--EDSVDNYTCHCWPGYTGAQCEIDL-------------------------N 341
Query: 1442 ACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQ-----CDELCNTVECLFDNFEC 1496
CNS+ CQ +G L+ E + + + Y C + C D EC
Sbjct: 342 ECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNEC 401
Query: 1497 QGN---------------SKTCKYDKYCADHFKDNHCDQ---GCNSEEC 1527
N + C +D + C GC ++C
Sbjct: 402 SSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQC 450
Score = 191 bits (485), Expect = 8e-48
Identities = 85/198 (42%), Positives = 116/198 (58%), Gaps = 8/198 (4%)
Query: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRY 666
Q++ C S+PCL+ G C D+ + Y C+C G SG +CE+N D+C SNPCIHG C D + Y
Sbjct: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAY 1198
Query: 667 SCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ------ 720
C C PG+TG C +DID C S+ C GATCI+ NG+ C+C C
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
Query: 721 -VNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNG 778
NE + C + GNCT + KC+C G+ G CE D +EC S+PC NGG C +L+N
Sbjct: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
Query: 779 YRCTCKKGFKGYNCQVNI 796
++C C F G C+V++
Sbjct: 1319 FQCLCDVAFAGERCEVDL 1336
Score = 187 bits (475), Expect = 1e-46
Identities = 84/202 (41%), Positives = 114/202 (56%), Gaps = 9/202 (4%)
Query: 455 MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVN 514
+ +N C+S+PC + C D + C C G+ G HCEL I+EC SNPC++ G C D+V
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVA 1196
Query: 515 RFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEEN---I 571
+ C C PG+TG C++DID+C S C NGA CI H NGY C C FTG C ++
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 572 DNCDPD----PCHH-GQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLV 626
C + C++ G C + C+C PG+ G C IDEC S PC+N G C DL+
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
Query: 627 NGYQCNCQPGTSGVNCEINFDD 648
N +QC C +G CE++ D
Sbjct: 1317 NKFQCLCDVAFAGERCEVDLAD 1338
Score = 186 bits (473), Expect = 2e-46
Identities = 78/197 (39%), Positives = 113/197 (57%), Gaps = 8/197 (4%)
Query: 872 IDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVN 931
+ ++ C S PC++ G C + SY C CP G+SG CE +ID+C +NPC +G +C D V
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVA 1196
Query: 932 TFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI--- 988
+ C C PG+TG C+ D++ C S C NG TC + N Y+C C F G C +
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 989 ----NECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044
NE T +C+NGG C + C+C GFTG +C +I+EC+S PC+N G C D L
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
Query: 1045 GTYRCSCPLGYTGKNCQ 1061
++C C + + G+ C+
Sbjct: 1317 NKFQCLCDVAFAGERCE 1333
Score = 179 bits (453), Expect = 4e-44
Identities = 82/189 (43%), Positives = 105/189 (55%), Gaps = 9/189 (4%)
Query: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179
C H G C + ++++C CPLG++G +CE +DEC SNPC HG CSD + Y C C PGY
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPGY 1206
Query: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEEN-IDDCARGPH---- 1234
GVNCE ++D CQ+ C NG TCI N + C C G C ++ + G
Sbjct: 1207 TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNL 1266
Query: 1235 -CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCR 1293
C NGG C + C C PGF GE CE DI+EC S+PC + G C L N + C+C
Sbjct: 1267 TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGL--CQDLLNKFQCLCD 1324
Query: 1294 SAFTGRHCE 1302
AF G CE
Sbjct: 1325 VAFAGERCE 1333
Score = 178 bits (451), Expect = 7e-44
Identities = 105/295 (35%), Positives = 140/295 (47%), Gaps = 39/295 (13%)
Query: 33 EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCR 91
+PC NE C+ G C CP + G C+ D C C NG TC Q LG C
Sbjct: 193 DPCKNEATCLN-EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC--QDALGAYFCD 249
Query: 92 CASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQ-VGFTGKECQWT-DACL 149
CA GF G+ C+ +T S+PCL+GG C + + Y C C GFTG C+ C
Sbjct: 250 CAPGFLGDHCELNTDE--CASQPCLHGGLC-VDGENRYSCNCTGSGFTGTHCETLMPLCW 306
Query: 150 SHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL---------- 199
S PC N +TC + ++C C G+TG +CE D+NEC+ CQ G C+
Sbjct: 307 SKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGR 365
Query: 200 --NLPGS--------YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQ-TGDFTFEC-- 246
LP S Y C C GFTG +C+ C+ +PC NGGTC G++T C
Sbjct: 366 ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPF 425
Query: 247 -NCLPGFEGS-TCERNIDDCPNHRCQNGGVCV----DGVNTYNCRCPPQWTGQFC 295
N F G C + C + +C N G C+ DG + ++C CP +TG C
Sbjct: 426 DNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 174 bits (441), Expect = 1e-42
Identities = 81/202 (40%), Positives = 107/202 (52%), Gaps = 13/202 (6%)
Query: 377 DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNT 436
+ C SNPC G C+ + Y C+CP G+ G C ++DEC SNPC H G C +
Sbjct: 1141 NVCNSNPCLHGGNCED--IYSSYHCSCPLGWSGKHCELNIDECF---SNPCIH-GNCSDR 1194
Query: 437 DGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI- 495
A+HC C GY G CE+DI+ C S C N ATC+ G++CLC F G C
Sbjct: 1195 VAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRL 1254
Query: 496 ------NECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCID 549
NE + C N G C + +C+C PGFTG C+ DID+C+S PC+NG C D
Sbjct: 1255 PSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
Query: 550 HPNGYECQCATGFTGVLCEENI 571
N ++C C F G CE ++
Sbjct: 1315 LLNKFQCLCDVAFAGERCEVDL 1336
Score = 162 bits (411), Expect = 3e-39
Identities = 74/186 (39%), Positives = 99/186 (53%), Gaps = 8/186 (4%)
Query: 531 IDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDS 590
+ ++ C+S PCL+G C D + Y C C G++G CE NID C +PC HG C D + +
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
Query: 591 YTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCE------- 643
Y C C PGY G C ID C S C N CI NGY C C +G C
Sbjct: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 644 INFDDCASNPCIH-GICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVN 702
+ ++ + C + G C + C+C PGFTG+ C DIDECAS+PC G C + +N
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
Query: 703 GFRCIC 708
F+C+C
Sbjct: 1318 KFQCLC 1323
Score = 161 bits (407), Expect = 8e-39
Identities = 75/207 (36%), Positives = 112/207 (54%), Gaps = 10/207 (4%)
Query: 681 IDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSG 740
+ ++ C SNPC G C + + + C CP G C ++EC SNPCIHGNC+ ++
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
Query: 741 YKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ------- 793
Y C C+ G+ G+NCEVD + C S+ C NG TC + NGY C C F G C+
Sbjct: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 794 VNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPN 853
V +E + C N G C + + C C +TG+ C+ + C+ +PC N +C++ N
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
Query: 854 FESYTCLCAPGWQGQRCTIDI-DECIS 879
+ CLC + G+RC +D+ D+ IS
Sbjct: 1318 --KFQCLCDVAFAGERCEVDLADDLIS 1342
Score = 159 bits (401), Expect = 4e-38
Identities = 75/214 (35%), Positives = 113/214 (52%), Gaps = 19/214 (8%)
Query: 1022 CLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQK 1081
CL ++N C+S+PCL+ G C D +Y CSCPLG++GK+C+ ++ C +PC + G C +
Sbjct: 1137 CL-QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDR 1194
Query: 1082 KAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY 1141
A C C G+ G C+V +C H C + CI+ N + C C +
Sbjct: 1195 VAAYHCTCEPGYTGVNCEVDIDNCQ----------SHQCANGATCISHTNGYSCLCFGNF 1244
Query: 1142 TGSYCEEQL-------DECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQ 1194
TG +C + +E + C +G C++F +C C PG+ G CE ++DEC +
Sbjct: 1245 TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASD 1304
Query: 1195 PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDD 1228
PC NGG C DL+N F+C C G CE ++ D
Sbjct: 1305 PCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 151 bits (382), Expect = 7e-36
Identities = 70/206 (33%), Positives = 101/206 (49%), Gaps = 48/206 (23%)
Query: 837 CSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYM 896
C+ NPC + C++ + SY C C GW G+ C ++IDEC S PC+ HG C + +Y
Sbjct: 1143 CNSNPCLHGGNCEDI--YSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYH 1199
Query: 897 CECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCL------------------ 938
C C PG++G++CE DID+C ++ C NG +C+ N +SCLC
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
Query: 939 ---------------------------PGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSY 971
PGFTG+ C+ D++EC S+PC NGG C D +N +
Sbjct: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
Query: 972 TCKCQAGFDGVHCENNINECTESSCF 997
C C F G CE ++ + S F
Sbjct: 1320 QCLCDVAFAGERCEVDLADDLISDIF 1345
Score = 151 bits (381), Expect = 9e-36
Identities = 72/201 (35%), Positives = 107/201 (53%), Gaps = 12/201 (5%)
Query: 112 SRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKC 170
S PCL+GG C + +Y C+C +G++GK C+ D C S+PC +G+ VA + C C
Sbjct: 1145 SNPCLHGGNCEDIY-SSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVA-AYHCTC 1202
Query: 171 LTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPS-- 228
G+TG CE D++ C C +G TC++ Y C C FTG++C +P
Sbjct: 1203 EPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGN 1261
Query: 229 -----PCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYN 283
C NGG C + +C C PGF G CE++ID+C + C NGG+C D +N +
Sbjct: 1262 EKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQ 1320
Query: 284 CRCPPQWTGQFCTEDVDECLL 304
C C + G+ C D+ + L+
Sbjct: 1321 CLCDVAFAGERCEVDLADDLI 1341
Score = 151 bits (381), Expect = 9e-36
Identities = 66/190 (34%), Positives = 99/190 (52%), Gaps = 7/190 (3%)
Query: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPG 251
C HGG C ++ SY C CP G++G++C+ C +PC++G + + C C PG
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVA--AYHCTCEPG 1205
Query: 252 FEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPN---- 307
+ G CE +ID+C +H+C NG C+ N Y+C C +TG+FC + + N
Sbjct: 1206 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265
Query: 308 -ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPE 366
C NGG C C+C G++G+ C ++ID+CA C G C D + F C+C
Sbjct: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1325
Query: 367 GKAGLLCHLD 376
AG C +D
Sbjct: 1326 AFAGERCEVD 1335
Score = 143 bits (360), Expect = 2e-33
Identities = 73/209 (34%), Positives = 105/209 (50%), Gaps = 14/209 (6%)
Query: 62 CQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTC 121
C + C N C +GG C + + C C G++G+ C+ + CF S PC++G
Sbjct: 1137 CLQLNVCNSNPCLHGGNC--EDIYSSYHCSCPLGWSGKHCELNIDE-CF-SNPCIHGNCS 1192
Query: 122 HMLSRDTYECTCQVGFTGKECQW-TDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE 180
++ Y CTC+ G+TG C+ D C SH CANG+TC + N +SC C FTG+ C
Sbjct: 1193 DRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCR 1250
Query: 181 TDVNECDIPGH------CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGG 234
+ G+ C +GG C +C C GFTG++C+ CA PCVNGG
Sbjct: 1251 QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGG 1310
Query: 235 TCRQTGDFTFECNCLPGFEGSTCERNIDD 263
C+ + F+C C F G CE ++ D
Sbjct: 1311 LCQDLLN-KFQCLCDVAFAGERCEVDLAD 1338
Score = 142 bits (358), Expect = 4e-33
Identities = 79/234 (33%), Positives = 108/234 (46%), Gaps = 45/234 (19%)
Query: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIG 1246
+++ C + PC +GG C D+ + + CSCP G G CE NID+C P C++ G C DR+
Sbjct: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP-CIH-GNCSDRVA 1196
Query: 1247 GYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-- 1304
Y C C PG+ G CE DI+ C S+ C++ + CI TN Y C+C FTG+ C
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT--CISHTNGYSCLCFGNFTGKFCRQSRL 1254
Query: 1305 -VDVC----PQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVH 1359
VC + C NGG C + C C PGF+G C+ +
Sbjct: 1255 PSTVCGNEKTNLTCYNGGNC---TEFQTELKCMCRPGFTGEWCEKDIDE----------- 1300
Query: 1360 TASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL 1413
CAS PC +GG C Q + C C F+G RCE+
Sbjct: 1301 ------------------CASDPCVNGGLC--QDLLNKFQCLCDVAFAGERCEV 1334
Score = 136 bits (343), Expect = 2e-31
Identities = 69/202 (34%), Positives = 101/202 (50%), Gaps = 16/202 (7%)
Query: 264 CPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYG 323
C ++ C +GG C D ++Y+C CP W+G+ C ++DEC P C + G C++R Y
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP--CIH-GNCSDRVAAYH 1199
Query: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLC---HLDDACI 380
C C G++G +C +ID+C C G+TCI +SC+C G C L
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
Query: 381 SN-----PCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVN 435
N C+ G C + C C G+ G C +D+DECA S+PC + G C +
Sbjct: 1260 GNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKDIDECA---SDPCVNGGLCQD 1314
Query: 436 TDGAFHCECLKGYAGPRCEMDI 457
F C C +AG RCE+D+
Sbjct: 1315 LLNKFQCLCDVAFAGERCEVDL 1336
Score = 132 bits (333), Expect = 3e-30
Identities = 64/207 (30%), Positives = 100/207 (48%), Gaps = 12/207 (5%)
Query: 142 CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL 201
C + C S+PC +G C + + + C C G++G+ CE +++EC C H G C +
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDEC-FSNPCIH-GNCSDR 1194
Query: 202 PGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNI 261
+Y C C G+TG C+ C C NG TC + + C C F G C ++
Sbjct: 1195 VAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTN-GYSCLCFGNFTGKFCRQSR 1253
Query: 262 -------DDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGT 314
++ N C NGG C + C C P +TG++C +D+DEC P C NGG
Sbjct: 1254 LPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGL 1311
Query: 315 CANRNGGYGCVCVNGWSGDDCSENIDD 341
C + + C+C ++G+ C ++ D
Sbjct: 1312 CQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 114 bits (284), Expect = 2e-24
Identities = 62/195 (31%), Positives = 93/195 (47%), Gaps = 17/195 (8%)
Query: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRC 92
PC++ G C ++ +C CP G+ G++C+ + D C N C +G + C C
Sbjct: 1147 PCLHGGNCEDIYSSY-HCSCPLGWSGKHCELNIDECFSNPCIHGN---CSDRVAAYHCTC 1202
Query: 93 ASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT------- 145
G+TG +C+ + S C NG TC + + Y C C FTGK C+ +
Sbjct: 1203 EPGYTGVNCEVDIDN--CQSHQCANGATC-ISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
Query: 146 -DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGS 204
+ + C NG CT + C C GFTG+ CE D++EC C +GG C +L
Sbjct: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC-ASDPCVNGGLCQDLLNK 1318
Query: 205 YQCQCPQGFTGQYCD 219
+QC C F G+ C+
Sbjct: 1319 FQCLCDVAFAGERCE 1333
Score = 99.4 bits (246), Expect = 4e-20
Identities = 56/161 (34%), Positives = 79/161 (49%), Gaps = 20/161 (12%)
Query: 34 PCVNEGMC----VTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKA 88
PC++ G C YH C C G+ G C+ D C+ ++C NG TC++
Sbjct: 1185 PCIH-GNCSDRVAAYH-----CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHT--NGY 1236
Query: 89 TCRCASGFTGEDCQYS--TSHPC---FVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ 143
+C C FTG+ C+ S S C + C NGG C + +C C+ GFTG+ C+
Sbjct: 1237 SCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTE-LKCMCRPGFTGEWCE 1295
Query: 144 W-TDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDV 183
D C S PC NG C + N+F C C F G++CE D+
Sbjct: 1296 KDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 60.1 bits (144), Expect = 3e-08
Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 14/109 (12%)
Query: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCE 898
PNP NA++ +P + T CA + C S PC N G+CH+ + C
Sbjct: 866 PNPTNNASL---NPVLVNVTQGCAGD----------NSCKSNPCHNGGVCHSRWDDFSCS 912
Query: 899 CPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQ 947
CP SG CEE + C +PC +G C + F C+ F G Q
Sbjct: 913 CPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQ 960
Score = 58.5 bits (140), Expect = 8e-08
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 496 NECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYE 555
N C+SNPC N G C + + F C CP +G C+ ++ C +PC +GA+C G+E
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 556 CQCATGFTG 564
C F G
Sbjct: 948 CIANAVFNG 956
Score = 58.2 bits (139), Expect = 1e-07
Identities = 32/89 (35%), Positives = 43/89 (48%), Gaps = 8/89 (8%)
Query: 1189 DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248
+ C++ PC NGG C + F CSCP T G CEE + C P C +G QC + G+
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSP-CPHGAQCQPVLQGF 946
Query: 1249 SCRCLPGFAGE------RCEGDINECLSN 1271
C F G+ R G+I L+N
Sbjct: 947 ECIANAVFNGQSGQILFRSNGNITRELTN 975
Score = 54.3 bits (129), Expect = 1e-06
Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972
+ C +NPC NGG C + FSC C P T K ++ C PC +G C + +
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSC-PALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 973 CKCQAGFDG 981
C A F+G
Sbjct: 948 CIANAVFNG 956
Score = 53.5 bits (127), Expect = 2e-06
Identities = 27/67 (40%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 112 SRPCLNGGTCHMLSR-DTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
S PC NGG CH SR D + C+C +GK C+ C PC +G+ C V F C
Sbjct: 893 SNPCHNGGVCH--SRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECIA 950
Query: 171 LTGFTGQ 177
F GQ
Sbjct: 951 NAVFNGQ 957
Score = 52.4 bits (124), Expect = 6e-06
Identities = 25/69 (36%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDSYT 592
+ C S PC NG C + + C C +G CEE + C PC HG QCQ + +
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFE 947
Query: 593 CICNPGYMG 601
CI N + G
Sbjct: 948 CIANAVFNG 956
Score = 52.4 bits (124), Expect = 6e-06
Identities = 24/69 (34%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010
N C S PC NGG C + ++C C A G CE + C S C +G C + F
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 1011 CLCPVGFTG 1019
C+ F G
Sbjct: 948 CIANAVFNG 956
Score = 52.0 bits (123), Expect = 7e-06
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 458 NECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQ 517
N C S+PC N C + F+C C G CE E+ C +PC + QC + F+
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 518 CLCPPGFTGPVCQI 531
C+ F G QI
Sbjct: 948 CIANAVFNGQSGQI 961
Score = 51.2 bits (121), Expect = 1e-05
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 9/103 (8%)
Query: 142 CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL 201
C ++C S+PC NG C + + FSC C +G+ CE +V C C HG C +
Sbjct: 885 CAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGF-SPCPHGAQCQPV 942
Query: 202 PGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTF 244
++C F GQ L+ NG R+ + TF
Sbjct: 943 LQGFECIANAVFNGQSGQILFRS-------NGNITRELTNITF 978
Score = 50.4 bits (119), Expect = 2e-05
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 759 NECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYT 818
N C SNPC NGG C + + + C+C G C+ + C +PC + C + G+
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 819 CHCVLPYTGKNCQ 831
C + G++ Q
Sbjct: 948 CIANAVFNGQSGQ 960
Score = 49.3 bits (116), Expect = 5e-05
Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 989 NECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYR 1048
N C + C NGG C + FSC CP +G C E+ C PC + C L +
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 1049 CSCPLGYTGKNCQTL 1063
C + G++ Q L
Sbjct: 948 CIANAVFNGQSGQIL 962
Score = 48.9 bits (115), Expect = 6e-05
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Query: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYS 667
+ C S+PC N G C + + C+C TSG CE C +PC HG C + +
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 668 CVCSPGFTGQ 677
C+ + F GQ
Sbjct: 948 CIANAVFNGQ 957
Score = 48.9 bits (115), Expect = 6e-05
Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 684 DECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHG-NCTGGLSGYK 742
+ C SNPC G C + + F C CP +C +V C +PC HG C L G++
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 743 CLCDAGWVG 751
C+ +A + G
Sbjct: 948 CIANAVFNG 956
Score = 48.5 bits (114), Expect = 8e-05
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC 1173
C + GVC + + C CP +G CEE + C +PC HGA C + G+ C
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFEC 948
Score = 48.1 bits (113), Expect = 1e-04
Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 14/109 (12%)
Query: 760 ECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTC 819
E NP N LVN +G G N C SNPC N G C ++C
Sbjct: 863 EFFPNPTNNASLNPVLVN-----VTQGCAGDN------SCKSNPCHNGGVCHSRWDDFSC 911
Query: 820 HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ 868
C +GK C+ V C +PC + A C+ P + + C+ + GQ
Sbjct: 912 SCPALTSGKACEEV-QWCGFSPCPHGAQCQ--PVLQGFECIANAVFNGQ 957
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGK 432
C D++C SNPCH G +C + + C+CP G C E+V C + PC H +
Sbjct: 885 CAGDNSCKSNPCHNGGVCHSRW--DDFSCSCPALTSGKAC-EEVQWCGFS---PCPHGAQ 938
Query: 433 CVNTDGAFHC 442
C F C
Sbjct: 939 CQPVLQGFEC 948
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 722 NECLSNPCIHGN-CTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780
N C SNPC +G C + C C A G CE + C +PC +G C ++ G+
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 781 CTCKKGFKGYNCQV 794
C F G + Q+
Sbjct: 948 CIANAVFNGQSGQI 961
Score = 47.4 bits (111), Expect = 2e-04
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 1027 NECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQ 1086
N C S+PC N G C + CSCP +GK C+ V C SPC + C +
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFE 947
Query: 1087 CLCPSGWAG 1095
C+ + + G
Sbjct: 948 CIANAVFNG 956
Score = 47.0 bits (110), Expect = 2e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 8/83 (9%)
Query: 626 VNGYQCNCQPGTSGVNCEINFDDCASNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDID 684
+N N G +G N C SNPC +G +C + +SC C +G+ C ++
Sbjct: 874 LNPVLVNVTQGCAGDN------SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQ 926
Query: 685 ECASNPCRKGATCINGVNGFRCI 707
C +PC GA C + GF CI
Sbjct: 927 WCGFSPCPHGAQCQPVLQGFECI 949
Score = 47.0 bits (110), Expect = 2e-04
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 6/74 (8%)
Query: 262 DDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG 321
+ C ++ C NGGVC + ++C CP +G+ C E+V C P C +G C G
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSP--CPHGAQCQPVLQG 945
Query: 322 YGCVC---VNGWSG 332
+ C+ NG SG
Sbjct: 946 FECIANAVFNGQSG 959
Score = 46.6 bits (109), Expect = 3e-04
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 1151 DECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210
+ C SNPC +G C + C C G CE EV C PC +G C ++ F+
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 1211 C 1211
C
Sbjct: 948 C 948
Score = 45.8 bits (107), Expect = 5e-04
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 424 SNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCM 483
SNPC + G C + F C C +G CE ++ C PC + A C + GF C+
Sbjct: 893 SNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIAN 951
Query: 484 PGFKG 488
F G
Sbjct: 952 AVFNG 956
Score = 45.1 bits (105), Expect = 9e-04
Identities = 48/181 (26%), Positives = 71/181 (39%), Gaps = 40/181 (22%)
Query: 1378 CASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDG 1437
C S+PC HGG+C Y C C +SG CEL + P C+ C+D+
Sbjct: 1143 CNSNPCLHGGNCEDIYSS--YHCSCPLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAY 1198
Query: 1438 VCDEACNSHACQ--WDGGDCSLTMENPWAN-CSSPLPCWDYINNQCDELCNTVECL-FDN 1493
C C+ + G +C + ++N ++ C++ C + N CL F N
Sbjct: 1199 HC-------TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNG--------YSCLCFGN 1243
Query: 1494 FE---CQ---------GNSK---TCKYDKYCADHFKDNH--CDQGCNSEECGWDGLDCAA 1536
F C+ GN K TC C + + C G E C D +CA+
Sbjct: 1244 FTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECAS 1303
Query: 1537 D 1537
D
Sbjct: 1304 D 1304
Score = 44.7 bits (104), Expect = 0.001
Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
Query: 572 DNCDPDPCHHGQ-CQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQ 630
++C +PCH+G C D ++C C G C +++ C SPC + +C ++ G++
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 631 CNCQPGTSGVNCEINF 646
C +G + +I F
Sbjct: 948 CIANAVFNGQSGQILF 963
Score = 43.9 bits (102), Expect = 0.002
Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 1261 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA 1320
C GD N C SNPC + G C +D+ C C + +G+ CE V C PC +G C
Sbjct: 885 CAGD-NSCKSNPCHNGGV--CHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQC- 939
Query: 1321 VASNMPDGFICRCPPGFSG 1339
+ GF C F+G
Sbjct: 940 --QPVLQGFECIANAVFNG 956
Score = 43.5 bits (101), Expect = 0.003
Identities = 25/72 (34%), Positives = 30/72 (41%), Gaps = 5/72 (6%)
Query: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS--CGQVKCRKGEQCVHTASGPR 1365
C PC NGG C + D F C CP SG C+ CG C G QC G
Sbjct: 891 CKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 1366 CFCPSPRDCESG 1377
C + + +SG
Sbjct: 948 CIANAVFNGQSG 959
Score = 43.5 bits (101), Expect = 0.003
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 307 NACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCM 363
N C NGG C +R + C C SG C E + C F+ C G+ C + F C+
Sbjct: 894 NPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFECI 949
Score = 43.1 bits (100), Expect = 0.003
Identities = 35/139 (25%), Positives = 45/139 (32%), Gaps = 66/139 (47%)
Query: 34 PCVNEGMCV------------------TYHNGTGY-CKCPEGFLGEYCQHR-DPCEKNRC 73
PC + G CV +YH +GY C C GF G +C+ + C N C
Sbjct: 347 PCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPC 406
Query: 74 QNGGTC---------------------------------VAQAMLGKATC---------- 90
QNGGTC Q L TC
Sbjct: 407 QNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHG 466
Query: 91 ---RCASGFTGEDCQYSTS 106
C SG+TG C+ +T+
Sbjct: 467 FSCLCPSGYTGSLCEIATT 485
Score = 41.6 bits (96), Expect = 0.010
Identities = 17/37 (45%), Positives = 23/37 (62%)
Query: 756 VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNC 792
V K+ C S PCQ+ G C NL Y+C C + ++G NC
Sbjct: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 40.8 bits (94), Expect = 0.017
Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 6/60 (10%)
Query: 771 TCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
T +N+ +G K G V D C S PC ++G C + Y C C PY G NC
Sbjct: 654 TLENISSGSSLNVKAGC------VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 40.8 bits (94), Expect = 0.017
Identities = 17/34 (50%), Positives = 20/34 (58%)
Query: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNC 642
D C S PC + GRCI+L YQC+C G NC
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 40.0 bits (92), Expect = 0.028
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 1227 DDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTN 1286
D+ + C NGG C R +SC C +G+ CE ++ C +PC C +
Sbjct: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPH--GAQCQPVLQ 944
Query: 1287 DYLCVCRSAFTGR 1299
+ C+ + F G+
Sbjct: 945 GFECIANAVFNGQ 957
Score = 38.5 bits (88), Expect = 0.083
Identities = 25/75 (33%), Positives = 29/75 (38%), Gaps = 9/75 (12%)
Query: 319 NGGYGCVCVN---GWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHL 375
N V VN G +GD+ C C G C R FSC CP +G C
Sbjct: 871 NASLNPVLVNVTQGCAGDN------SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 924
Query: 376 DDACISNPCHKGALC 390
C +PC GA C
Sbjct: 925 VQWCGFSPCPHGAQC 939
Score = 37.7 bits (86), Expect = 0.14
Identities = 12/30 (40%), Positives = 19/30 (63%)
Query: 424 SNPCEHAGKCVNTDGAFHCECLKGYAGPRC 453
S PC+ G+C+N ++ C+C + Y GP C
Sbjct: 678 SQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 37.4 bits (85), Expect = 0.18
Identities = 24/75 (32%), Positives = 28/75 (37%), Gaps = 7/75 (9%)
Query: 1339 GARCQSSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCES--GCASSPCQHGGSCHPQR 1393
G +SC C G C C CP S + CE C SPC HG C P
Sbjct: 884 GCAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVL 943
Query: 1394 QPPYYSCQCAPPFSG 1408
Q + C F+G
Sbjct: 944 QG--FECIANAVFNG 956
Score = 37.0 bits (84), Expect = 0.24
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 1375 ESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412
++ C S+PC +GG CH + +SC C SG CE
Sbjct: 888 DNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACE 923
Score = 36.6 bits (83), Expect = 0.31
Identities = 13/32 (40%), Positives = 18/32 (56%)
Query: 1029 CSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNC 1060
C S PC + G C++ +Y+C C Y G NC
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 36.2 bits (82), Expect = 0.41
Identities = 14/34 (41%), Positives = 19/34 (55%)
Query: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDC 908
D C S+PC + G C N SY C+C + G +C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 36.2 bits (82), Expect = 0.41
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 1151 DECASNPCQHGATCSDFIGGYRCECVPGYQGVNC 1184
D C S PCQ C + Y+C+C Y+G NC
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 36.2 bits (82), Expect = 0.41
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Query: 62 CQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTC 121
C + C+ N C NGG C + +C C + +G+ C+ C S PC +G C
Sbjct: 885 CAGDNSCKSNPCHNGGVC--HSRWDDFSCSCPALTSGKACE--EVQWCGFS-PCPHGAQC 939
Query: 122 HMLSRDTYECTCQVGFTGKECQ 143
+ + +EC F G+ Q
Sbjct: 940 QPVLQG-FECIANAVFNGQSGQ 960
Score = 35.0 bits (79), Expect = 0.92
Identities = 14/34 (41%), Positives = 20/34 (58%)
Query: 1189 DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLC 1222
D C++QPCQ+ G CI+L ++C C G C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 34.7 bits (78), Expect = 1.2
Identities = 12/32 (37%), Positives = 19/32 (59%)
Query: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVC 529
C+S PC + G+C++ +QC C + GP C
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 34.3 bits (77), Expect = 1.6
Identities = 12/32 (37%), Positives = 19/32 (59%)
Query: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHC 984
C S+PC++ G C + SY C C ++G +C
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 34.3 bits (77), Expect = 1.6
Identities = 15/32 (46%), Positives = 18/32 (56%)
Query: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV 223
CQ G C+NL SYQC C + + G C YV
Sbjct: 681 CQSRGRCINLWLSYQCDCHRPYEGPNCLREYV 712
Score = 32.0 bits (71), Expect = 7.8
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Query: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCA 93
PC N G+C + + C CP G+ C+ C + C +G C Q +L C
Sbjct: 895 PCHNGGVCHSRWDDFS-CSCPALTSGKACEEVQWCGFSPCPHGAQC--QPVLQGFECIAN 951
Query: 94 SGFTGEDCQ 102
+ F G+ Q
Sbjct: 952 AVFNGQSGQ 960
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 324 bits (831), Expect = 6e-88
Identities = 158/414 (38%), Positives = 216/414 (52%), Gaps = 46/414 (11%)
Query: 336 SENIDDCAFASCTPGSTC-IDRVASFSC--MCPEGKAGLLCHLDDACISNPCHKGALC-D 391
SE CA C PG+ C ++C M P G C + PCH GALC
Sbjct: 36 SEPPSACASDPCAPGTECQATESGGYTCGPMEPRG-----------CATQPCHHGALCVP 84
Query: 392 TNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGP 451
P + C C G++G C D+DECA S PC H C N + C C GYAG
Sbjct: 85 QGPDPTGFRCYCVPGFQGPRCELDIDECA---SRPCHHGATCRNLADRYECHCPLGYAGV 141
Query: 452 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVD 511
CEM+++EC S PC + +CLD +G F C+C PG+ G C+L+++ECQS PC + G C D
Sbjct: 142 TCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHD 201
Query: 512 KVNRFQCLCP-PGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEEN 570
VN F+C C G+ G C+ ++ +C+S PC + A C++ + C C G++G LCE +
Sbjct: 202 LVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
Query: 571 IDNCDPDPCHH-GQCQDGID---------------------SYTCICNPGYMGAICSDQI 608
D C PC H G+C D + C C PG+ GA C ++
Sbjct: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEV 321
Query: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIH-GICMDGINRYS 667
DEC S PCLN G C DL NG+QC+C G +G CE + D+C S+PC+H G C D + Y
Sbjct: 322 DECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYI 381
Query: 668 CVCSPGFTGQRCNIDIDECASNPCRKGATCI----NGVNGFRCICPEGPHHPSC 717
C C + G+ C++ + C + C ATCI +GV+ + C CP G H P C
Sbjct: 382 CRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 314 bits (804), Expect = 8e-85
Identities = 157/452 (34%), Positives = 222/452 (49%), Gaps = 53/452 (11%)
Query: 799 CASNPCLNQGTC-FDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVC-KESPNFES 856
CAS+PC C + GYTC + P C+ PC + A+C + P+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP----------RGCATQPCHHGALCVPQGPDPTG 91
Query: 857 YTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCL 916
+ C C PG+QG RC +DIDEC S+PC + C N Y C CP G++G+ CE ++D+C
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 917 ANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQ 976
+ PC +GGSC+DGV +F C+C PG+ G +CQ D++EC S+PC +GGTC D VN + C C
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
Query: 977 -AGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCL 1035
G++G HCE + EC + C + +C++G+ SF CLC G++G C + +EC+S PC
Sbjct: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQ 271
Query: 1036 NEGTCVD---------------GLGTYR------CSCPLGYTGKNCQTLVNLCSRSPCKN 1074
+ G C+ G ++R C CP G+ G +C V+ C+ PC N
Sbjct: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLN 331
Query: 1075 KGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY 1134
G C QC CP G+AG C+ C + C H G C + +
Sbjct: 332 GGHCQDLPNGFQCHCPDGYAGPTCEEDVDEC----------LSDPCLHGGTCSDTVAGYI 381
Query: 1135 CQCPLGYTGSYCEEQLDECASNPCQHGATC----SDFIGGYRCECVPGYQGVNCEYEV-- 1188
C+CP + G C QL C + C ATC + Y C C PG G C
Sbjct: 382 CRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTF 441
Query: 1189 DECQNQPCQ---NGGTCIDLVNHFKCSCPPGT 1217
P Q G + L F+ + P GT
Sbjct: 442 SVMAGSPIQASVPAGGPLGLALRFRTTLPAGT 473
Score = 313 bits (803), Expect = 1e-84
Identities = 156/409 (38%), Positives = 210/409 (51%), Gaps = 46/409 (11%)
Query: 378 ACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTD 437
AC S+PC G C +G Y C P +G CA + PC H CV
Sbjct: 41 ACASDPCAPGTECQATE-SGGYTCG-PMEPRG---------CA---TQPCHHGALCVPQG 86
Query: 438 G---AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELE 494
F C C+ G+ GPRCE+DI+EC S PC + ATC + + C C G+ GV CE+E
Sbjct: 87 PDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
Query: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGY 554
++EC S PC++ G C+D V F+C+C PG+ G CQ+D+D+C S PC +G C D NG+
Sbjct: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
Query: 555 ECQCA-TGFTGVLCEENIDNCDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQIDECY 612
C CA TG+ G CE + C PC H+ C +G+ S+ C+C PGY G +C DEC
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
Query: 613 SSPCLNDGRCIDLVN---------------------GYQCNCQPGTSGVNCEINFDDCAS 651
SSPC + GRC+ + G+ C+C PG G +C + D+CAS
Sbjct: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
Query: 652 NPCIH-GICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPE 710
PC++ G C D N + C C G+ G C D+DEC S+PC G TC + V G+ C CPE
Sbjct: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPE 386
Query: 711 GPHHPSCYSQVNECLSNPC-IHGNC----TGGLSGYKCLCDAGWVGINC 754
C Q+ C + C + C G+ Y C C G G C
Sbjct: 387 TWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 302 bits (774), Expect = 2e-81
Identities = 151/419 (36%), Positives = 206/419 (49%), Gaps = 45/419 (10%)
Query: 686 CASNPCRKGATC-INGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCT----GGLSG 740
CAS+PC G C G+ C GP P C + PC HG +G
Sbjct: 42 CASDPCAPGTECQATESGGYTC----GPMEP------RGCATQPCHHGALCVPQGPDPTG 91
Query: 741 YKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECA 800
++C C G+ G CE+D +EC S PC +G TC NL + Y C C G+ G C++ +DECA
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 801 SNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCL 860
S PCL+ G+C D + + C C Y G CQ L C PC + C + N + C
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVN--GFRCD 209
Query: 861 CA-PGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
CA G++G C ++ EC S PC ++ C GS+ C C PG+SG CE D D+C ++P
Sbjct: 210 CAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSP 269
Query: 920 CQNGGSCMD--------GVNT-------------FSCLCLPGFTGDKCQTDMNECLSEPC 958
CQ+GG C+ GV F C C PGF G C +++EC S PC
Sbjct: 270 CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPC 329
Query: 959 KNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT 1018
NGG C D N + C C G+ G CE +++EC C +GGTC D + + C CP +
Sbjct: 330 LNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWG 389
Query: 1019 GSFCLHEINECSSHPCLNEGTCV----DGLGTYRCSCPLGYTGKNC--QTLVNLCSRSP 1071
G C ++ C H C TC+ G+ +Y C CP G G C T ++ + SP
Sbjct: 390 GRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSP 448
Score = 302 bits (774), Expect = 2e-81
Identities = 151/419 (36%), Positives = 216/419 (51%), Gaps = 52/419 (12%)
Query: 837 CSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQG--- 893
C+ +PC C+ + ES C P ++ C ++PC + LC QG
Sbjct: 42 CASDPCAPGTECQAT---ESGGYTCGP--------MEPRGCATQPCHHGALCV-PQGPDP 89
Query: 894 -SYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNE 952
+ C C PGF G CE DID+C + PC +G +C + + + C C G+ G C+ +++E
Sbjct: 90 TGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDE 149
Query: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCL 1012
C S PC +GG+C D V S+ C C G+ G C+ +++EC C +GGTC D +N F C
Sbjct: 150 CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD 209
Query: 1013 CP-VGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSP 1071
C G+ G+ C E+ EC+S PC + +C++GLG++RC C GY+G+ C+ + C+ SP
Sbjct: 210 CAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSP 269
Query: 1072 CKNKGTCVQKK---------------------AESQCLCPSGWAGAYCDVPNVSCDIAAS 1110
C++ G C+Q+ A C CP G+ GA C V D AS
Sbjct: 270 CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADC---GVEVDECAS 326
Query: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGG 1170
R C + G C + N C CP GY G CEE +DEC S+PC HG TCSD + G
Sbjct: 327 RP-------CLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAG 379
Query: 1171 YRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDL----VNHFKCSCPPGTRGLLCEEN 1225
Y C C + G +C ++ CQ C TCI + V+ + C CPPGT G C +N
Sbjct: 380 YICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
Score = 296 bits (758), Expect = 2e-79
Identities = 147/385 (38%), Positives = 198/385 (51%), Gaps = 40/385 (10%)
Query: 302 CLLQPNACQNGGTCANRNG---GYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVA 358
C QP C +G C + G+ C CV G+ G C +ID+CA C G+TC +
Sbjct: 71 CATQP--CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLAD 128
Query: 359 SFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD 417
+ C CP G AG+ C ++ D C S PC G C G + C C GY G C D+D
Sbjct: 129 RYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGV--GSFRCVCAPGYGGTRCQLDLD 186
Query: 418 ECAMANSNPCEHAGKCVNTDGAFHCECL-KGYAGPRCEMDINECHSDPCQNDATCLDKIG 476
EC S PC H G C + F C+C GY G CE ++ EC S PC+++A+CL+ +G
Sbjct: 187 EC---QSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLG 243
Query: 477 GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNR--------------------- 515
F CLC PG+ G CE++ +EC S+PC + G+C+ + +
Sbjct: 244 SFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAG 303
Query: 516 FQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCD 575
F C CPPGF G C +++D+C+S PCLNG C D PNG++C C G+ G CEE++D C
Sbjct: 304 FLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECL 363
Query: 576 PDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDL----VNGYQ 630
DPC H G C D + Y C C + G CS Q+ C C CI + V+ Y
Sbjct: 364 SDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYV 423
Query: 631 CNCQPGTSGVNCEIN--FDDCASNP 653
C+C PGT G C N F A +P
Sbjct: 424 CHCPPGTHGPFCGQNTTFSVMAGSP 448
Score = 291 bits (746), Expect = 4e-78
Identities = 150/411 (36%), Positives = 193/411 (46%), Gaps = 48/411 (11%)
Query: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVD---GVNT 281
CA PC G C+ T + C + C C +G +CV
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP----------RGCATQPCHHGALCVPQGPDPTG 91
Query: 282 YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD 341
+ C C P + G C D+DEC +P C +G TC N Y C C G++G C +D+
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCEMEVDE 149
Query: 342 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYI 400
CA A C G +C+D V SF C+C G G C LD D C S PC G C + L +
Sbjct: 150 CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTC--HDLVNGFR 207
Query: 401 CTCP-QGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINE 459
C C GY+G C +V ECA A PCEH C+ G+F C C GY+G CE+D +E
Sbjct: 208 CDCAGTGYEGTHCEREVLECASA---PCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDE 264
Query: 460 CHSDPCQNDATCLDK---------------------IGGFTCLCMPGFKGVHCELEINEC 498
C S PCQ+ CL + GF C C PGF+G C +E++EC
Sbjct: 265 CASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDEC 324
Query: 499 QSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQC 558
S PC+N G C D N FQC CP G+ GP C+ D+D+C S PCL+G C D GY C+C
Sbjct: 325 ASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRC 384
Query: 559 ATGFTGVLCEENIDNCDPDPCHHGQC-----QDGIDSYTCICNPGYMGAIC 604
+ G C + C C + G+ SY C C PG G C
Sbjct: 385 PETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 288 bits (736), Expect = 6e-77
Identities = 142/417 (34%), Positives = 201/417 (48%), Gaps = 55/417 (13%)
Query: 877 CISKPCMNHGLCHNTQ-GSYMCEC--PPGFSGMDCEEDIDDCLANPCQNGGSCMD---GV 930
C S PC C T+ G Y C P G C PC +G C+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRG------------CATQPCHHGALCVPQGPDP 89
Query: 931 NTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINE 990
F C C+PGF G +C+ D++EC S PC +G TC + + Y C C G+ GV CE ++E
Sbjct: 90 TGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDE 149
Query: 991 CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCS 1050
C + C +GG+C+DG+ SF C+C G+ G+ C +++EC S PC + GTC D + +RC
Sbjct: 150 CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD 209
Query: 1051 CP-LGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAA 1109
C GY G +C+ V C+ +PC++ +C++ +CLC G++G C+V C +
Sbjct: 210 CAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSP 269
Query: 1110 SRRGVLVEHLCQHSGVCINAGNT---------------------HYCQCPLGYTGSYCEE 1148
CQH G C+ + C CP G+ G+ C
Sbjct: 270 ----------CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV 319
Query: 1149 QLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNH 1208
++DECAS PC +G C D G++C C GY G CE +VDEC + PC +GGTC D V
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAG 379
Query: 1209 FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCM----DRIGGYSCRCLPGFAGERC 1261
+ C CP G C + C +G C C+ + Y C C PG G C
Sbjct: 380 YICRCPETWGGRDCSVQLTGC-QGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 282 bits (722), Expect = 3e-75
Identities = 143/416 (34%), Positives = 203/416 (48%), Gaps = 51/416 (12%)
Query: 915 CLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDY---VNSY 971
C ++PC G C + C P + C ++PC +G C +
Sbjct: 42 CASDPCAPGTECQ-ATESGGYTCGP--------MEPRGCATQPCHHGALCVPQGPDPTGF 92
Query: 972 TCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSS 1031
C C GF G CE +I+EC C +G TC + + + C CP+G+ G C E++EC+S
Sbjct: 93 RCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS 152
Query: 1032 HPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCP- 1090
PCL+ G+C+DG+G++RC C GY G CQ ++ C PC + GTC +C C
Sbjct: 153 APCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAG 212
Query: 1091 SGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQL 1150
+G+ G +C+ + C A C+H+ C+ + C C GY+G CE
Sbjct: 213 TGYEGTHCEREVLECASAP----------CEHNASCLEGLGSFRCLCWPGYSGELCEVDE 262
Query: 1151 DECASNPCQHGATC-------------SDFIG--------GYRCECVPGYQGVNCEYEVD 1189
DECAS+PCQHG C + F G G+ C C PG++G +C EVD
Sbjct: 263 DECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVD 322
Query: 1190 ECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYS 1249
EC ++PC NGG C DL N F+C CP G G CEE++D+C P CL+GG C D + GY
Sbjct: 323 ECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDP-CLHGGTCSDTVAGYI 381
Query: 1250 CRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQL----TNDYLCVCRSAFTGRHC 1301
CRC + G C + C + C + CI + + Y+C C G C
Sbjct: 382 CRCPETWGGRDCSVQLTGCQGHTCPLAAT--CIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 280 bits (715), Expect = 2e-74
Identities = 149/440 (33%), Positives = 200/440 (45%), Gaps = 51/440 (11%)
Query: 953 CLSEPCKNGGTC-SDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVD---GINS 1008
C S+PC G C + YTC C C +G CV
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP----------RGCATQPCHHGALCVPQGPDPTG 91
Query: 1009 FSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCS 1068
F C C GF G C +I+EC+S PC + TC + Y C CPLGY G C+ V+ C+
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 1069 RSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCIN 1128
+PC + G+C+ +C+C G+ G C + C C H G C +
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQ----------SQPCAHGGTCHD 201
Query: 1129 AGNTHYCQCP-LGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE 1187
N C C GY G++CE ++ ECAS PC+H A+C + +G +RC C PGY G CE +
Sbjct: 202 LVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
Query: 1188 VDECQNQPCQNGGTCIDLVNH---------------------FKCSCPPGTRGLLCEENI 1226
DEC + PCQ+GG C+ + F C CPPG G C +
Sbjct: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEV 321
Query: 1227 DDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTN 1286
D+CA P CLNGG C D G+ C C G+AG CE D++ECLS+PC G+ C
Sbjct: 322 DECASRP-CLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGT--CSDTVA 378
Query: 1287 DYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTC-AVASNMPDGFICRCPPGFSGARC-QS 1344
Y+C C + GR C + C C TC + + ++C CPPG G C Q+
Sbjct: 379 GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
Query: 1345 SCGQVKCRKGEQCVHTASGP 1364
+ V Q A GP
Sbjct: 439 TTFSVMAGSPIQASVPAGGP 458
Score = 253 bits (646), Expect = 2e-66
Identities = 137/370 (37%), Positives = 183/370 (49%), Gaps = 37/370 (10%)
Query: 33 EPCVNEGMCVTYH-NGTGY-CKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKAT 89
+PC + +CV + TG+ C C GF G C+ D C C +G TC + + +
Sbjct: 74 QPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATC--RNLADRYE 131
Query: 90 CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DAC 148
C C G+ G C+ S PCL+GG+C + ++ C C G+ G CQ D C
Sbjct: 132 CHCPLGYAGVTCEMEVDE--CASAPCLHGGSC-LDGVGSFRCVCAPGYGGTRCQLDLDEC 188
Query: 149 LSHPCANGSTCTTVANQFSCKCL-TGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQC 207
S PCA+G TC + N F C C TG+ G CE +V EC C+H +CL GS++C
Sbjct: 189 QSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLEC-ASAPCEHNASCLEGLGSFRC 247
Query: 208 QCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGD--------------FTFE------CN 247
C G++G+ C+ CA SPC +GG C Q D F+F C+
Sbjct: 248 LCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCH 307
Query: 248 CLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPN 307
C PGFEG+ C +D+C + C NGG C D N + C CP + G C EDVDECL P
Sbjct: 308 CPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDP- 366
Query: 308 ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI----DRVASFSCM 363
C +GGTC++ GY C C W G DCS + C +C +TCI V S+ C
Sbjct: 367 -CLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCH 425
Query: 364 CPEGKAGLLC 373
CP G G C
Sbjct: 426 CPPGTHGPFC 435
Score = 249 bits (637), Expect = 2e-65
Identities = 134/404 (33%), Positives = 183/404 (45%), Gaps = 68/404 (16%)
Query: 147 ACLSHPCANGSTCTTVAN--------------------------------QFSCKCLTGF 174
AC S PCA G+ C + F C C+ GF
Sbjct: 41 ACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
Query: 175 TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGG 234
G +CE D++EC C HG TC NL Y+C CP G+ G C+ CA +PC++GG
Sbjct: 101 QGPRCELDIDEC-ASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGG 159
Query: 235 TCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCP-PQWTGQ 293
+C G +F C C PG+ G+ C+ ++D+C + C +GG C D VN + C C + G
Sbjct: 160 SCLD-GVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGT 218
Query: 294 FCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTC 353
C +V EC P C++ +C G + C+C G+SG+ C + D+CA + C G C
Sbjct: 219 HCEREVLECASAP--CEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRC 276
Query: 354 IDR---------------------VASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCD 391
+ R A F C CP G G C ++ D C S PC G C
Sbjct: 277 LQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQ 336
Query: 392 TNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGP 451
P NG + C CP GY G C EDVDEC S+PC H G C +T + C C + + G
Sbjct: 337 DLP-NG-FQCHCPDGYAGPTCEEDVDECL---SDPCLHGGTCSDTVAGYICRCPETWGGR 391
Query: 452 RCEMDINECHSDPCQNDATCL----DKIGGFTCLCMPGFKGVHC 491
C + + C C ATC+ + + C C PG G C
Sbjct: 392 DCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 238 bits (606), Expect = 7e-62
Identities = 119/325 (36%), Positives = 156/325 (48%), Gaps = 36/325 (11%)
Query: 1120 CQHSGVCINAG---NTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV 1176
C H +C+ G C C G+ G CE +DECAS PC HGATC + Y C C
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCP 135
Query: 1177 PGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCL 1236
GY GV CE EVDEC + PC +GG+C+D V F+C C PG G C+ ++D+C P C
Sbjct: 136 LGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP-CA 194
Query: 1237 NGGQCMDRIGGYSCRCL-PGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSA 1295
+GG C D + G+ C C G+ G CE ++ EC S PC E + C++ + C+C
Sbjct: 195 HGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPC--EHNASCLEGLGSFRCLCWPG 252
Query: 1296 FTGRHCETFVDVCPQMPCLNGGTC------------------AVASNMPDGFICRCPPGF 1337
++G CE D C PC +GG C A + GF+C CPPGF
Sbjct: 253 YSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF 312
Query: 1338 SGARC---QSSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCESG---CASSPCQHGGS 1388
GA C C C G C +G +C CP + CE C S PC HGG+
Sbjct: 313 EGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGT 372
Query: 1389 CHPQRQPPYYSCQCAPPFSGSRCEL 1413
C Y C+C + G C +
Sbjct: 373 C--SDTVAGYICRCPETWGGRDCSV 395
Score = 211 bits (536), Expect = 9e-54
Identities = 123/384 (32%), Positives = 169/384 (44%), Gaps = 85/384 (22%)
Query: 1143 GSYCEEQLDECASN-----------------------------PCQHGATC---SDFIGG 1170
G+ E CAS+ PC HGA C G
Sbjct: 32 GTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTG 91
Query: 1171 YRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCA 1230
+RC CVPG+QG CE ++DEC ++PC +G TC +L + ++C CP G G+ CE +D+CA
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLC 1290
P CL+GG C+D +G + C C PG+ G RC+ D++EC S PC+ G+ C L N + C
Sbjct: 152 SAP-CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGT--CHDLVNGFRC 208
Query: 1291 VCR-SAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARC---QSSC 1346
C + + G HCE V C PC + +C F C C PG+SG C + C
Sbjct: 209 DCAGTGYEGTHCEREVLECASAPCEHNASCLEGLG---SFRCLCWPGYSGELCEVDEDEC 265
Query: 1347 GQVKCRKGEQCVHT---------------------ASGPRCFCP---SPRDC---ESGCA 1379
C+ G +C+ A+G C CP DC CA
Sbjct: 266 ASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECA 325
Query: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVC 1439
S PC +GG C Q P + C C ++G CE CLS C G C
Sbjct: 326 SRPCLNGGHC--QDLPNGFQCHCPDGYAGPTCE-------EDVDECLSDPC---LHGGTC 373
Query: 1440 DEACNSHACQ----WDGGDCSLTM 1459
+ + C+ W G DCS+ +
Sbjct: 374 SDTVAGYICRCPETWGGRDCSVQL 397
Score = 166 bits (419), Expect = 3e-40
Identities = 98/314 (31%), Positives = 134/314 (42%), Gaps = 73/314 (23%)
Query: 51 CKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPC 109
C CP G+ G C+ D C C +GG+C+ +G C CA G+ G CQ
Sbjct: 132 CHCPLGYAGVTCEMEVDECASAPCLHGGSCLDG--VGSFRCVCAPGYGGTRCQLDLDE-- 187
Query: 110 FVSRPCLNGGTCHMLSRDTYECTCQ-VGFTGKECQWTDA-CLSHPCANGSTCTTVANQFS 167
S+PC +GGTCH L + C C G+ G C+ C S PC + ++C F
Sbjct: 188 CQSQPCAHGGTCHDLVNG-FRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFR 246
Query: 168 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLN-------------LPGSYQ-------- 206
C C G++G+ CE D +EC CQHGG CL PG++
Sbjct: 247 CLCWPGYSGELCEVDEDEC-ASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFL 305
Query: 207 CQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPN 266
C CP GF G C CA PC+NGG C+ + F+C+C G+ G TCE ++D+C +
Sbjct: 306 CHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPN-GFQCHCPDGYAGPTCEEDVDECLS 364
Query: 267 HRCQNGGVCVD------------------------------------------GVNTYNC 284
C +GG C D GV++Y C
Sbjct: 365 DPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVC 424
Query: 285 RCPPQWTGQFCTED 298
CPP G FC ++
Sbjct: 425 HCPPGTHGPFCGQN 438
Score = 126 bits (316), Expect = 3e-28
Identities = 59/153 (38%), Positives = 77/153 (50%), Gaps = 7/153 (4%)
Query: 837 CSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCH-NTQGSY 895
C+P+PC + C++ F+++ C C PGW+G RC +D C S PC G CH + G +
Sbjct: 1060 CAPSPCLHDGACRDL--FDAFACACGPGWEGPRCEAHVDPCHSAPCA-RGRCHTHPDGRF 1116
Query: 896 MCECPPGFSGMDCEEDI--DDCLAN-PCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNE 952
C CPPGF G C + +C N C +G C G +C CL G G +CQ
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
Query: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCE 985
C + PC NGGTC C C A F G CE
Sbjct: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 115 bits (287), Expect = 7e-25
Identities = 65/164 (39%), Positives = 82/164 (50%), Gaps = 13/164 (7%)
Query: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGIC---MDGINRYS 667
C SPCL+DG C DL + + C C PG G CE + D C S PC G C DG R+
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDG--RFE 1117
Query: 668 CVCSPGFTGQRCNIDI--DECASN-PCRKGATCINGVNGFRCICPEGPHHPSCYSQVNEC 724
C C PGF G RC + + EC+ N C G+ C G C C EG C C
Sbjct: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
Query: 725 LSNPCIHG---NCTGGLSGYKCLCDAGWVGINCEVDKNECLSNP 765
+NPC++G GG+S +C+C+A + G CEV K L P
Sbjct: 1178 EANPCLNGGTCRAAGGVS--ECICNARFSGQFCEVAKGLPLPLP 1219
Score = 114 bits (286), Expect = 9e-25
Identities = 53/152 (34%), Positives = 73/152 (48%), Gaps = 4/152 (2%)
Query: 1153 CASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCS 1212
CA +PC H C D + C C PG++G CE VD C + PC G F+C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 1213 CPPGTRGLLCEENI--DDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLS 1270
CPPG G C + +C+ CL+G C +C CL G AG+RC+ C +
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 1271 NPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
NPC + G+ C C+C + F+G+ CE
Sbjct: 1180 NPCLNGGT--CRAAGGVSECICNARFSGQFCE 1209
Score = 112 bits (281), Expect = 3e-24
Identities = 58/151 (38%), Positives = 72/151 (47%), Gaps = 5/151 (3%)
Query: 649 CASNPCIH-GICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCI 707
CA +PC+H G C D + ++C C PG+ G RC +D C S PC +G + F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 708 CPEGPHHPSCYSQV--NECLSN-PCIHGN-CTGGLSGYKCLCDAGWVGINCEVDKNECLS 763
CP G P C V EC N C+ G+ C GG C C G G C+V C +
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 764 NPCQNGGTCDNLVNGYRCTCKKGFKGYNCQV 794
NPC NGGTC C C F G C+V
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 111 bits (277), Expect = 1e-23
Identities = 58/154 (37%), Positives = 72/154 (46%), Gaps = 5/154 (3%)
Query: 108 PCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ-WTDACLSHPCANGSTCTTVANQF 166
P PCL+ G C L D + C C G+ G C+ D C S PCA G T +F
Sbjct: 1058 PVCAPSPCLHDGACRDLF-DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRF 1116
Query: 167 SCKCLTGFTGQKCETDV--NECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVP 224
C+C GF G +C V EC + C G C + C C +G GQ C +P
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
Query: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE 258
C +PC+NGGTCR G + EC C F G CE
Sbjct: 1177 CEANPCLNGGTCRAAGGVS-ECICNARFSGQFCE 1209
Score = 110 bits (274), Expect = 2e-23
Identities = 55/147 (37%), Positives = 66/147 (44%), Gaps = 3/147 (2%)
Query: 425 NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP 484
+PC H G C + AF C C G+ GPRCE ++ CHS PC G F C C P
Sbjct: 1063 SPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPP 1122
Query: 485 GFKGVHCELEI--NECQSN-PCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC 541
GF G C L + EC N C++ C C C G G CQ+ C + PC
Sbjct: 1123 GFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPC 1182
Query: 542 LNGAKCIDHPNGYECQCATGFTGVLCE 568
LNG C EC C F+G CE
Sbjct: 1183 LNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 109 bits (272), Expect = 4e-23
Identities = 51/149 (34%), Positives = 70/149 (46%), Gaps = 4/149 (2%)
Query: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
C PC +D C D F C C PG++G CE ++ C S PC RF+C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 520 CPPGFTGPVCQIDI--DDCS-STPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP 576
CPPGF GP C++ + +CS + CL+G+ C C C G G C+ C+
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 577 DPC-HHGQCQDGIDSYTCICNPGYMGAIC 604
+PC + G C+ CICN + G C
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 107 bits (266), Expect = 2e-22
Identities = 50/151 (33%), Positives = 72/151 (47%), Gaps = 3/151 (1%)
Query: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCL 1012
C PC + G C D +++ C C G++G CE +++ C + C G F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 1013 CPVGFTGSFCLHEI--NECSSH-PCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSR 1069
CP GF G C + ECS + CL+ C G CSC G G+ CQ C
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 1070 SPCKNKGTCVQKKAESQCLCPSGWAGAYCDV 1100
+PC N GTC S+C+C + ++G +C+V
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 106 bits (264), Expect = 3e-22
Identities = 53/141 (37%), Positives = 70/141 (49%), Gaps = 7/141 (4%)
Query: 574 CDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNG-YQC 631
C P PC H G C+D D++ C C PG+ G C +D C+S+PC GRC +G ++C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
Query: 632 NCQPGTSGVNCE--INFDDCASN-PCIHGI-CMDGINRYSCVCSPGFTGQRCNIDIDECA 687
C PG G C + +C+ N C+ G C G +C C G GQRC + C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 688 SNPCRKGATCINGVNGFRCIC 708
+NPC G TC CIC
Sbjct: 1179 ANPCLNGGTCRAAGGVSECIC 1199
Score = 104 bits (260), Expect = 9e-22
Identities = 49/155 (31%), Positives = 75/155 (48%), Gaps = 3/155 (1%)
Query: 915 CLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCK 974
C +PC + G+C D + F+C C PG+ G +C+ ++ C S PC G + + C+
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 975 CQAGFDGVHCENNI--NECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSS 1031
C GF G C + EC+ + +C +G C G + +C C G G C C +
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 1032 HPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNL 1066
+PCLN GTC G C C ++G+ C+ L
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGL 1214
Score = 104 bits (260), Expect = 9e-22
Identities = 53/152 (34%), Positives = 74/152 (48%), Gaps = 6/152 (3%)
Query: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNG-YEC 556
C +PC+++G C D + F C C PG+ GP C+ +D C S PC G +C HP+G +EC
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 557 QCATGFTGVLCEENIDNCDPD---PCHHGQ-CQDGIDSYTCICNPGYMGAICSDQIDECY 612
+C GF G C + + + C G C+ G + C C G G C C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEI 644
++PCLN G C +C C SG CE+
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 104 bits (260), Expect = 9e-22
Identities = 49/149 (32%), Positives = 67/149 (44%), Gaps = 3/149 (2%)
Query: 877 CISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
C PC++ G C + ++ C C PG+ G CE +D C + PC G F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 937 CLPGFTGDKCQTDM--NEC-LSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTE 993
C PGF G +C+ + EC L+ C +G C + C C G G C+ C
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 994 SSCFNGGTCVDGINSFSCLCPVGFTGSFC 1022
+ C NGGTC C+C F+G FC
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 101 bits (252), Expect = 8e-21
Identities = 57/159 (35%), Positives = 72/159 (45%), Gaps = 7/159 (4%)
Query: 1191 CQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSC 1250
C PC + G C DL + F C+C PG G CE ++D C P C G G + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP-CARGRCHTHPDGRFEC 1118
Query: 1251 RCLPGFAGERCEGDI--NECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVC 1308
RC PGF G RC + EC N +GS C + C C G+ C+ C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGS-PCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
Query: 1309 PQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCG 1347
PCLNGGTC A + + C C FSG C+ + G
Sbjct: 1178 EANPCLNGGTCRAAGGVSE---CICNARFSGQFCEVAKG 1213
Score = 100 bits (249), Expect = 2e-20
Identities = 57/167 (34%), Positives = 79/167 (47%), Gaps = 18/167 (10%)
Query: 373 CHLDDACISNPC-HKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAG 431
C C +PC H GA D L + C C G++G C VD C +S PC G
Sbjct: 1054 CRGAPVCAPSPCLHDGACRD---LFDAFACACGPGWEGPRCEAHVDPC---HSAPCAR-G 1106
Query: 432 KC-VNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKI---GGF---TCLCMP 484
+C + DG F C C G+ GPRC + + S C + TCLD GG C C+
Sbjct: 1107 RCHTHPDGRFECRCPPGFGGPRCRLPVP---SKECSLNVTCLDGSPCEGGSPAANCSCLE 1163
Query: 485 GFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
G G C++ C++NPC+N G C +C+C F+G C++
Sbjct: 1164 GLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 97.8 bits (242), Expect = 1e-19
Identities = 52/153 (33%), Positives = 71/153 (46%), Gaps = 3/153 (1%)
Query: 342 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYI 400
CA + C C D +F+C C G G C D C S PC +G C T+P +G++
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHP-DGRFE 1117
Query: 401 CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINEC 460
C CP G+ G C V + + C C A +C CL+G AG RC++ C
Sbjct: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
Query: 461 HSDPCQNDATCLDKIGGFTCLCMPGFKGVHCEL 493
++PC N TC G C+C F G CE+
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 95.5 bits (236), Expect = 6e-19
Identities = 51/153 (33%), Positives = 66/153 (43%), Gaps = 4/153 (2%)
Query: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNC 284
CAPSPC++ G CR D F C C PG+EG CE ++D C + C G + C
Sbjct: 1060 CAPSPCLHDGACRDLFD-AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFEC 1118
Query: 285 RCPPQWTGQFCTEDV--DECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDC 342
RCPP + G C V EC L C +G C + C C+ G +G C C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNV-TCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
Query: 343 AFASCTPGSTCIDRVASFSCMCPEGKAGLLCHL 375
C G TC C+C +G C +
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 94.7 bits (234), Expect = 1e-18
Identities = 47/153 (30%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 724 CLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCT 782
C +PC+H G C + C C GW G CE + C S PC G + + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 783 CKKGFKGYNCQVNI--DECASN-PCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSP 839
C GF G C++ + EC+ N CL+ C C C+ G+ CQ PC
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 840 NPCENAAVCKESPNFESYTCLCAPGWQGQRCTI 872
NPC N C+ + C+C + GQ C +
Sbjct: 1180 NPCLNGGTCRAAGGVSE--CICNARFSGQFCEV 1210
Score = 94.0 bits (232), Expect = 2e-18
Identities = 50/158 (31%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Query: 142 CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL 201
C+ C PC + C + + F+C C G+ G +CE V+ C C G +
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCH-SAPCARGRCHTHP 1112
Query: 202 PGSYQCQCPQGFTGQYCDSLYVP---CAPS-PCVNGGTCRQTGDFTFECNCLPGFEGSTC 257
G ++C+CP GF G C L VP C+ + C++G C + G C+CL G G C
Sbjct: 1113 DGRFECRCPPGFGGPRC-RLPVPSKECSLNVTCLDGSPC-EGGSPAANCSCLEGLAGQRC 1170
Query: 258 ERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
+ C + C NGG C C C +++GQFC
Sbjct: 1171 QVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 93.2 bits (230), Expect = 3e-18
Identities = 49/159 (30%), Positives = 68/159 (42%), Gaps = 19/159 (11%)
Query: 761 CLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISG-YTC 819
C +PC + G C +L + + C C G++G C+ ++D C S PC +G C G + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCA-RGRCHTHPDGRFEC 1118
Query: 820 HCV---------LPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRC 870
C LP K C + +PCE + + C C G GQRC
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGS--------PAANCSCLEGLAGQRC 1170
Query: 871 TIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE 909
+ C + PC+N G C G C C FSG CE
Sbjct: 1171 QVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 92.0 bits (227), Expect = 6e-18
Identities = 88/313 (28%), Positives = 111/313 (35%), Gaps = 72/313 (23%)
Query: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327
C S+PC+ + + Y C R C T PC +G C P
Sbjct: 42 CASDPCAPGTECQATE-SGGYTC---GPMEPRGCAT-------QPCHHGALCVPQGPDPT 90
Query: 1328 GFICRCPPGFSGARCQ---SSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCE---SGC 1378
GF C C PGF G RC+ C C G C + A C CP + CE C
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
Query: 1379 ASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGV 1438
AS+PC HGGSC + C CAP + G+RC+L C SQ C A G
Sbjct: 151 ASAPCLHGGSC--LDGVGSFRCVCAPGYGGTRCQL-------DLDECQSQPC---AHGGT 198
Query: 1439 CDEACNSHACQWDG-GDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECL------- 1490
C + N C G G E C+S PC N C E + CL
Sbjct: 199 CHDLVNGFRCDCAGTGYEGTHCEREVLECAS-APCEH--NASCLEGLGSFRCLCWPGYSG 255
Query: 1491 ----FDNFECQGNSKTCKYDKYC------------------ADHFKDN-----HCDQGCN 1523
D EC S C++ C A F+ HC G
Sbjct: 256 ELCEVDEDECA--SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE 313
Query: 1524 SEECGWDGLDCAA 1536
+CG + +CA+
Sbjct: 314 GADCGVEVDECAS 326
Score = 90.9 bits (224), Expect = 1e-17
Identities = 51/146 (34%), Positives = 62/146 (42%), Gaps = 4/146 (2%)
Query: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179
C H G C + + C C G+ G CE +D C S PC G + G + C C PG+
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Query: 1180 QGVNCEYEV--DECQ-NQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCL 1236
G C V EC N C +G C CSC G G C+ C P CL
Sbjct: 1125 GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANP-CL 1183
Query: 1237 NGGQCMDRIGGYSCRCLPGFAGERCE 1262
NGG C G C C F+G+ CE
Sbjct: 1184 NGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 88.6 bits (218), Expect = 7e-17
Identities = 45/159 (28%), Positives = 63/159 (39%), Gaps = 11/159 (6%)
Query: 1029 CSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCL 1088
C+ PCL++G C D + C+C G+ G C+ V+ C +PC +C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 1089 CPSGWAGAYC--DVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYC 1146
CP G+ G C VP+ C + + C C C C G G C
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVT---------CLDGSPCEGGSPAANCSCLEGLAGQRC 1170
Query: 1147 EEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE 1185
+ C +NPC +G TC G C C + G CE
Sbjct: 1171 QVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 83.6 bits (205), Expect = 2e-15
Identities = 54/168 (32%), Positives = 71/168 (42%), Gaps = 21/168 (12%)
Query: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327
C +PC +G+ C L + + C C + G CE VD C PC G PD
Sbjct: 1060 CAPSPCLHDGA--CRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR----CHTHPD 1113
Query: 1328 G-FICRCPPGFSGARCQ-----SSCG-QVKCRKGEQCVHTASGPRCFC---PSPRDCE-- 1375
G F CRCPPGF G RC+ C V C G C + C C + + C+
Sbjct: 1114 GRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVP 1173
Query: 1376 -SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPP 1422
C ++PC +GG+C + C C FSG CE+ P P
Sbjct: 1174 TLPCEANPCLNGGTC--RAAGGVSECICNARFSGQFCEVAKGLPLPLP 1219
Score = 80.5 bits (197), Expect = 2e-14
Identities = 46/154 (29%), Positives = 60/154 (38%), Gaps = 9/154 (5%)
Query: 306 PNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCP 365
P+ C + G C + + C C GW G C ++D C A C G F C CP
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCP 1121
Query: 366 EGKAGLLCHLDDACISNPCHKGALC-DTNPLNG---QYICTCPQGYKGADCTEDVDECAM 421
G G C L S C C D +P G C+C +G G C C
Sbjct: 1122 PGFGGPRCRL--PVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC-- 1177
Query: 422 ANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEM 455
+NPC + G C G C C ++G CE+
Sbjct: 1178 -EANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 79.3 bits (194), Expect = 4e-14
Identities = 47/161 (29%), Positives = 60/161 (37%), Gaps = 13/161 (8%)
Query: 1066 LCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGV 1125
+C+ SPC + G C C C GW G C+ C A RG H
Sbjct: 1059 VCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTH------- 1111
Query: 1126 CINAGNTHYCQCPLGYTGSYCEEQL--DECASN-PCQHGATCSDFIGGYRCECVPGYQGV 1182
C+CP G+ G C + EC+ N C G+ C C C+ G G
Sbjct: 1112 ---PDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQ 1168
Query: 1183 NCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCE 1223
C+ C+ PC NGGTC +C C G CE
Sbjct: 1169 RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 73.6 bits (179), Expect = 2e-12
Identities = 48/151 (31%), Positives = 63/151 (41%), Gaps = 14/151 (9%)
Query: 2 PALRPALLWALLALWLCCAAPA-HALQCRDGYEPCVN----EGMCVTYHNGTGYCKCPEG 56
P L L + C P +C +PC + G C T+ +G C+CP G
Sbjct: 1064 PCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPG 1123
Query: 57 FLGEYCQHRDPCEKNRCQNGGTCV----AQAMLGKATCRCASGFTGEDCQYSTSHPCFVS 112
F G C R P C TC+ + A C C G G+ CQ T PC +
Sbjct: 1124 FGGPRC--RLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL-PC-EA 1179
Query: 113 RPCLNGGTCHMLSRDTYECTCQVGFTGKECQ 143
PCLNGGTC + EC C F+G+ C+
Sbjct: 1180 NPCLNGGTCR-AAGGVSECICNARFSGQFCE 1209
Score = 68.6 bits (166), Expect = 7e-11
Identities = 49/157 (31%), Positives = 68/157 (43%), Gaps = 32/157 (20%)
Query: 1307 VCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQS---SCGQVKCRKGE-------- 1355
VC PCL+ G C ++ D F C C PG+ G RC++ C C +G
Sbjct: 1059 VCAPSPCLHDGAC---RDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGR 1115
Query: 1356 ---QCVHTASGPRCFCPSP-RDCESGCA---SSPCQHGGSCHPQRQPPYYSCQCAPPFSG 1408
+C GPRC P P ++C SPC+ GGS P +C C +G
Sbjct: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCE-GGS-------PAANCSCLEGLAG 1167
Query: 1409 SRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNS 1445
RC++ T P P CL+ +A GV + CN+
Sbjct: 1168 QRCQVPTLPCEANP--CLNGGTC-RAAGGVSECICNA 1201
Score = 59.3 bits (142), Expect = 5e-08
Identities = 26/65 (40%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Query: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQ 557
C +PC N G C+ N F C CP FTGP C + C PCL A C + P+G+ C
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 558 CATGF 562
F
Sbjct: 870 AEATF 874
Score = 58.9 bits (141), Expect = 6e-08
Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 9/80 (11%)
Query: 991 CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTC---VDGL--- 1044
C+ CFNGGTC+ N F C CP FTG C ++ C PCL TC DG
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 1045 --GTYRCSCPLGYTGKNCQT 1062
T+R P ++G N +
Sbjct: 870 AEATFREGPPAAFSGHNASS 889
Score = 54.3 bits (129), Expect = 1e-06
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972
D C +PC NGG+C+ N F C C FTG C + C +PC TC + + +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 973 CKCQAGF 979
C +A F
Sbjct: 868 CVAEATF 874
Score = 52.8 bits (125), Expect = 4e-06
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 756 VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDIS 815
V ++ C +PC NGGTC N + CTC F G C + C PCL TC +
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 816 GYTC 819
G+ C
Sbjct: 865 GFVC 868
Score = 51.6 bits (122), Expect = 9e-06
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC 480
M + +PC + G C+ T FHC C + GP C + C PC ATC + GF C
Sbjct: 810 MCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
Query: 481 LCMPGFK 487
+ F+
Sbjct: 869 VAEATFR 875
Score = 51.2 bits (121), Expect = 1e-05
Identities = 27/67 (40%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 51 CKCPEGFLGEYCQHRD-PCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPC 109
C C EG G+ CQ PCE N C NGGTC +A G + C C + F+G+ C+ + P
Sbjct: 1159 CSCLEGLAGQRCQVPTLPCEANPCLNGGTC--RAAGGVSECICNARFSGQFCEVAKGLPL 1216
Query: 110 FVSRPCL 116
+ P L
Sbjct: 1217 PLPFPLL 1223
Score = 50.8 bits (120), Expect = 2e-05
Identities = 30/85 (35%), Positives = 39/85 (45%), Gaps = 14/85 (16%)
Query: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327
C +PC + G+ C+ ND+ C C + FTG C + CP PCL TC +PD
Sbjct: 811 CSPDPCFNGGT--CLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATC---EEVPD 864
Query: 1328 GFICRC--------PPGFSGARCQS 1344
GF+C P FSG S
Sbjct: 865 GFVCVAEATFREGPPAAFSGHNASS 889
Score = 50.8 bits (120), Expect = 2e-05
Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 114 PCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 168
PC NGGTC +++ + + CTC FTG C C PC +TC V + F C
Sbjct: 815 PCFNGGTC-LVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDGFVC 868
Score = 48.9 bits (115), Expect = 6e-05
Identities = 33/101 (32%), Positives = 45/101 (44%), Gaps = 14/101 (13%)
Query: 644 INFDDCASNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVN 702
++ D C+ +PC +G C+ N + C C FTG C + C PC ATC +
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 703 GFRCICP----EGPHHPSCYSQVNECLSNPCIHGNCTGGLS 739
GF C+ EGP P+ +S N G GGLS
Sbjct: 865 GFVCVAEATFREGP--PAAFSGHN------ASSGRLLGGLS 897
Score = 48.5 bits (114), Expect = 8e-05
Identities = 54/214 (25%), Positives = 69/214 (32%), Gaps = 53/214 (24%)
Query: 1371 PRDCESGCASS-----------------------------PCQHGGSCHPQ-RQPPYYSC 1400
P + S CAS PC HG C PQ P + C
Sbjct: 35 PSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRC 94
Query: 1401 QCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTME 1460
C P F G RCEL C S+ C A C + + C G +T E
Sbjct: 95 YCVPGFQGPRCEL-------DIDECASRPCHHGA---TCRNLADRYECHCPLGYAGVTCE 144
Query: 1461 NPWANCSSPL-----PCWDYINN---QCDELCNTVECLFDNFECQGNSKTCKYDKYCADH 1512
C+S C D + + C C D ECQ S+ C + C D
Sbjct: 145 MEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQ--SQPCAHGGTCHDL 202
Query: 1513 FKDNHCD---QGCNSEECGWDGLDCAADQPENLA 1543
CD G C + L+CA+ E+ A
Sbjct: 203 VNGFRCDCAGTGYEGTHCEREVLECASAPCEHNA 236
Score = 47.8 bits (112), Expect = 1e-04
Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 4/67 (5%)
Query: 142 CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGH-CQHGGTCLN 200
C D C PC NG TC N F C C FTG C + PG C TC
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC---AQQLWCPGQPCLPPATCEE 861
Query: 201 LPGSYQC 207
+P + C
Sbjct: 862 VPDGFVC 868
Score = 47.4 bits (111), Expect = 2e-04
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC 1173
C + G C+ N +C CP +TG C +QL C PC ATC + G+ C
Sbjct: 816 CFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
Score = 47.0 bits (110), Expect = 2e-04
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 794 VNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPN 853
V+ D C+ +PC N GTC + + C C +TG C L C PC A C+E P
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVP- 863
Query: 854 FESYTCL 860
+ + C+
Sbjct: 864 -DGFVCV 869
Score = 47.0 bits (110), Expect = 2e-04
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPC-HHGQCQDGIDSYT 592
D CS PC NG C+ N + C C FTG C + + C PC C++ D +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 593 CI 594
C+
Sbjct: 868 CV 869
Score = 47.0 bits (110), Expect = 2e-04
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Query: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNC 284
C+P PC NGGTC T + F C C F G TC + + CP C C + + + C
Sbjct: 811 CSPDPCFNGGTCLVTWN-DFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
Score = 46.6 bits (109), Expect = 3e-04
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 1189 DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248
D C PC NGGTC+ N F C+CP G C + + G CL C + G+
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL--WCPGQPCLPPATCEEVPDGF 866
Query: 1249 SC 1250
C
Sbjct: 867 VC 868
Score = 46.2 bits (108), Expect = 4e-04
Identities = 27/101 (26%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 836 PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSY 895
P P P +N++ E +S W + D C PC N G C T +
Sbjct: 778 PFFPLPLDNSSQPSELGGRQS--------WNLTAGCVSEDMCSPDPCFNGGTCLVTWNDF 829
Query: 896 MCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
C CP F+G C + + C PC +C + + F C+
Sbjct: 830 HCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Score = 46.2 bits (108), Expect = 4e-04
Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCL 1012
C +PC NGGTC N + C C A F G C + C C TC + + F C+
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 1013 CPVGF 1017
F
Sbjct: 870 AEATF 874
Score = 45.8 bits (107), Expect = 5e-04
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 2/86 (2%)
Query: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
C DPC N TCL F C C F G C ++ C PC+ C + + F C+
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 520 CPPGF-TGPVCQIDIDDCSSTPCLNG 544
F GP + SS L G
Sbjct: 870 AEATFREGPPAAFSGHNASSGRLLGG 895
Score = 45.4 bits (106), Expect = 7e-04
Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 1182 VNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENI 1226
+ CE ++C+ PC +GG+C+DL HF+C C RG C + I
Sbjct: 601 LGCERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 45.4 bits (106), Expect = 7e-04
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 684 DECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI-HGNCTGGLSGYK 742
D C+ +PC G TC+ N F C CP P+C Q+ C PC+ C G+
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 743 CLCDA 747
C+ +A
Sbjct: 868 CVAEA 872
Score = 44.7 bits (104), Expect = 0.001
Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Query: 572 DNCDPDPCHHG-QCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQ 630
D C PDPC +G C + + C C + G C+ Q+ C PCL C ++ +G+
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 631 C 631
C
Sbjct: 868 C 868
Score = 44.7 bits (104), Expect = 0.001
Identities = 20/53 (37%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 189 PGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGD 241
P C +GGTCL + C CP FTG C + + C PC+ TC + D
Sbjct: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPD 864
Score = 43.9 bits (102), Expect = 0.002
Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 1/61 (1%)
Query: 1151 DECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210
D C+ +PC +G TC + C C + G C ++ C QPC TC ++ + F
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 1211 C 1211
C
Sbjct: 868 C 868
Score = 43.5 bits (101), Expect = 0.003
Identities = 24/63 (38%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 1306 DVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARC--QSSCGQVKCRKGEQCVHTASG 1363
D+C PC NGGTC V N F C CP F+G C Q C C C G
Sbjct: 809 DMCSPDPCFNGGTCLVTWN---DFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDG 865
Query: 1364 PRC 1366
C
Sbjct: 866 FVC 868
Score = 43.1 bits (100), Expect = 0.003
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 262 DDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG 321
D C C NGG C+ N ++C CP +TG C + + C QP C TC G
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQP--CLPPATCEEVPDG 865
Query: 322 YGCV 325
+ CV
Sbjct: 866 FVCV 869
Score = 42.4 bits (98), Expect = 0.006
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 299 VDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVA 358
V E + P+ C NGGTC + C C ++G C++ + C C P +TC +
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 359 SFSCM 363
F C+
Sbjct: 865 GFVCV 869
Score = 42.0 bits (97), Expect = 0.007
Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 62 CQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTC 121
C D C + C NGGTC+ C C + FTG C P +PCL TC
Sbjct: 805 CVSEDMCSPDPCFNGGTCL--VTWNDFHCTCPANFTGPTCAQQLWCP---GQPCLPPATC 859
Query: 122 HMLSRDTYECTCQVGF 137
+ D + C + F
Sbjct: 860 EEVP-DGFVCVAEATF 874
Score = 39.7 bits (91), Expect = 0.037
Identities = 14/41 (34%), Positives = 23/41 (56%)
Query: 1148 EQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEV 1188
E+ ++C PC HG +C D +RC+C ++G C E+
Sbjct: 604 ERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 39.7 bits (91), Expect = 0.037
Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 3/73 (4%)
Query: 717 CYSQVNECLSNPCIHGN-CTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL 775
C S+ + C +PC +G C + + C C A + G C + C PC TC+ +
Sbjct: 805 CVSE-DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEV 862
Query: 776 VNGYRCTCKKGFK 788
+G+ C + F+
Sbjct: 863 PDGFVCVAEATFR 875
Score = 39.3 bits (90), Expect = 0.049
Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 1227 DDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTN 1286
D C+ P C NGG C+ + C C F G C + C PC + C ++ +
Sbjct: 809 DMCSPDP-CFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPAT--CEEVPD 864
Query: 1287 DYLCVCRSAF 1296
++CV + F
Sbjct: 865 GFVCVAEATF 874
Score = 38.1 bits (87), Expect = 0.11
Identities = 15/37 (40%), Positives = 20/37 (54%)
Query: 497 ECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDI 533
+C+ PCV+ G CVD F+C C GP C +I
Sbjct: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 37.7 bits (86), Expect = 0.14
Identities = 19/67 (28%), Positives = 26/67 (38%), Gaps = 2/67 (2%)
Query: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCI-HGICMDGINRYS 667
D C PC N G C+ N + C C +G C C PC+ C + + +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 668 CVCSPGF 674
CV F
Sbjct: 868 CVAEATF 874
Score = 36.2 bits (82), Expect = 0.41
Identities = 13/32 (40%), Positives = 18/32 (56%)
Query: 426 PCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI 457
PC H G CV+ F C+C + + GP C +I
Sbjct: 613 PCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 36.2 bits (82), Expect = 0.41
Identities = 18/55 (32%), Positives = 21/55 (38%)
Query: 340 DDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNP 394
D C+ C G TC+ F C CP G C C PC A C+ P
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVP 863
Score = 36.2 bits (82), Expect = 0.41
Identities = 13/34 (38%), Positives = 19/34 (55%)
Query: 1065 NLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098
++CS PC N GTC+ + C CP+ + G C
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842
Score = 35.8 bits (81), Expect = 0.54
Identities = 18/70 (25%), Positives = 24/70 (34%), Gaps = 6/70 (8%)
Query: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGK 432
C +D C +PC G C + CTCP + G C + + PC
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVT--WNDFHCTCPANFTGPTCAQQL----WCPGQPCLPPAT 858
Query: 433 CVNTDGAFHC 442
C F C
Sbjct: 859 CEEVPDGFVC 868
Score = 35.4 bits (80), Expect = 0.70
Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 752 INCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNC 792
+ CE + +C PC +GG+C +L +RC C + +G C
Sbjct: 601 LGCE-RREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 34.7 bits (78), Expect = 1.2
Identities = 12/38 (31%), Positives = 18/38 (47%)
Query: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI 571
+ C PC++G C+D + C CA G C + I
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 34.7 bits (78), Expect = 1.2
Identities = 16/47 (34%), Positives = 20/47 (42%), Gaps = 1/47 (2%)
Query: 33 EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTC 79
+PC N G C+ N +C CP F G C + C C TC
Sbjct: 814 DPCFNGGTCLVTWNDF-HCTCPANFTGPTCAQQLWCPGQPCLPPATC 859
Score = 34.3 bits (77), Expect = 1.6
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 5/54 (9%)
Query: 1375 ESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRC--ELY-TAPPSTPPATC 1425
E C+ PC +GG+C + C C F+G C +L+ P PPATC
Sbjct: 808 EDMCSPDPCFNGGTCLVTWND--FHCTCPANFTGPTCAQQLWCPGQPCLPPATC 859
Score = 33.9 bits (76), Expect = 2.0
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 5/71 (7%)
Query: 926 CMDGVNTFSCLCLPGFTGDK----CQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDG 981
C+ V L LP G+ C+ +C PC +GG+C D + C C G
Sbjct: 579 CLQDVRVDGHLLLPEDLGENVLLGCER-REQCRPLPCVHGGSCVDLWTHFRCDCARPHRG 637
Query: 982 VHCENNINECT 992
C + I T
Sbjct: 638 PTCADEIPAAT 648
Score = 33.9 bits (76), Expect = 2.0
Identities = 11/34 (32%), Positives = 19/34 (55%)
Query: 797 DECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
++C PC++ G+C D + + C C P+ G C
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 33.5 bits (75), Expect = 2.7
Identities = 11/34 (32%), Positives = 19/34 (55%)
Query: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNC 642
++C PC++ G C+DL ++C+C G C
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 33.5 bits (75), Expect = 2.7
Identities = 15/37 (40%), Positives = 18/37 (48%), Gaps = 1/37 (2%)
Query: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNI 261
C P PCV+GG+C F C+C G TC I
Sbjct: 609 CRPLPCVHGGSCVDLWTH-FRCDCARPHRGPTCADEI 644
Score = 33.1 bits (74), Expect = 3.5
Identities = 30/108 (27%), Positives = 37/108 (34%), Gaps = 11/108 (10%)
Query: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS----CGQVKCRKGEQCVHTASG 1363
CP C+ G A+AS P G S A+ + C Q G + G
Sbjct: 540 CPARLCVASGPVALASTAS---ATPLPAGISSAQLGDATFAGCLQDVRVDGHLLLPEDLG 596
Query: 1364 PRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRC 1411
R C PC HGGSC ++ C CA P G C
Sbjct: 597 ENVLLGCER--REQCRPLPCVHGGSCVDLW--THFRCDCARPHRGPTC 640
Score = 33.1 bits (74), Expect = 3.5
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 1028 ECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNC 1060
+C PC++ G+CVD +RC C + G C
Sbjct: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 32.7 bits (73), Expect = 4.5
Identities = 11/42 (26%), Positives = 18/42 (42%)
Query: 142 CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDV 183
C+ + C PC +G +C + F C C G C ++
Sbjct: 603 CERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 32.3 bits (72), Expect = 5.9
Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 569 ENIDNCDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQI 608
E + C P PC H G C D + C C + G C+D+I
Sbjct: 604 ERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 32.0 bits (71), Expect = 7.8
Identities = 16/43 (37%), Positives = 19/43 (44%), Gaps = 1/43 (2%)
Query: 984 CENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI 1026
CE +C C +GG+CVD F C C G C EI
Sbjct: 603 CERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 305 bits (780), Expect = 5e-82
Identities = 193/614 (31%), Positives = 273/614 (44%), Gaps = 101/614 (16%)
Query: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQC 207
C + PC NG CT+ + E D P H G PG Y C
Sbjct: 48 CAAQPCRNGGVCTS----------------RPEPD------PQHPAPAGE----PG-YSC 80
Query: 208 QCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFT--FECNCLPGFEGSTCERNIDDCP 265
CP G +G C + PCA +PC +G + + + C C G+EG P
Sbjct: 81 TCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEG----------P 130
Query: 266 NHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCV 325
N C+ + P Q T++ D+ L + A T + G V
Sbjct: 131 N--CEQALPSLPATGWTESMAPRQLQPVPATQEPDKILPRSQATVTLPTWQPKTGQK--V 186
Query: 326 CVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSC-------MCPEGKAGLL------ 372
W D E I D A + + S+ R+ SF + + A L+
Sbjct: 187 VEMKW---DQVEVIPDIACGNASSNSSAGGRLVSFEVPQNTSVKIRQDATASLILLWKVT 243
Query: 373 ------CHLDDACISNPCH-KGALCDTNPL----NGQYICTCPQGYKGADCTED------ 415
C L D P G L + N +I G+ T+
Sbjct: 244 ATGFQQCSLIDGRSVTPLQASGGLVLLEEMLALGNNHFI-----GFVNDSVTKSIVALRL 298
Query: 416 -----VDEC----AMANSNPCEHAGKCVN--TDGAFHCECLKGYAGPRCEMDINECHSDP 464
V C + AN C GKC ++ F C C + Y G CE + + C P
Sbjct: 299 TLVVKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKP 357
Query: 465 CQNDATCLDKI-----GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
CQN+A+C+D FTC+C+PG+ G C+ +I+ C +PC N C+ ++ F C
Sbjct: 358 CQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQ 417
Query: 520 CPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPC 579
CP G+ G C+ +D C+S+PC N C + C C+ GFTG C + ID C PC
Sbjct: 418 CPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPC 477
Query: 580 HHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSG 639
HG C+ SY C+C+PGY G C ++ +EC S+PCLN C DLVNGY+C C G
Sbjct: 478 AHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKG 537
Query: 640 VNCEINFDDCASNPCIHGIC--MDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC 697
+CE+ D CA+ C++G DG+N +C+C+PGFTG+ C+IDI+EC SNPC G +C
Sbjct: 538 THCELYKDPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSC 596
Query: 698 INGVNGFRCICPEG 711
++ NG+ C CP G
Sbjct: 597 LDQPNGYNCHCPHG 610
Score = 259 bits (662), Expect = 2e-68
Identities = 123/304 (40%), Positives = 164/304 (53%), Gaps = 13/304 (4%)
Query: 766 CQNGGTCDNLVNG--YRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFD-----DISGYT 818
C G C + + CTC++ + G C+ D C PC N +C D D S +T
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 819 CHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECI 878
C C+ YTG+ CQ+ + C +PC N A C S +TC C G+ G C +D C
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISS--LSGFTCQCPEGYFGSACEEKVDPCA 435
Query: 879 SKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCL 938
S PC N+G C+ + C C PGF+G C + ID C +PC +G +C ++ CLC
Sbjct: 436 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTSYKCLCD 494
Query: 939 PGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFN 998
PG+ G C+ + NECLS PC N TC D VN Y C C A + G HCE + C SC N
Sbjct: 495 PGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLN 554
Query: 999 GGTC-VDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTG 1057
G TC DG+N +C+C GFTG C +INEC S+PC + G+C+D Y C CP G+ G
Sbjct: 555 GATCDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVG 613
Query: 1058 KNCQ 1061
NC+
Sbjct: 614 ANCE 617
Score = 256 bits (654), Expect = 2e-67
Identities = 122/322 (37%), Positives = 168/322 (52%), Gaps = 17/322 (5%)
Query: 255 STCERNIDDCPNHRCQNGGVCVDGVN--TYNCRCPPQWTGQFCTEDVDECLLQPNACQNG 312
STC + C G C + T++C C Q+ G FC E+ D C +P CQN
Sbjct: 305 STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFC-EEYDACQRKP--CQNN 361
Query: 313 GTCANRN-----GGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEG 367
+C + N + CVC+ G++G+ C ID C C G+TCI ++ F+C CPEG
Sbjct: 362 ASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEG 421
Query: 368 KAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNP 426
G C D C S+PC C + ++ + C C G+ G C + +D CA++ P
Sbjct: 422 YFGSACEEKVDPCASSPCQNNGTCYVDGVH--FTCNCSPGFTGPTCAQLIDFCALS---P 476
Query: 427 CEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF 486
C H G C + ++ C C GY G CE + NEC S PC N ATC D + G+ C+C+ +
Sbjct: 477 CAH-GTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEY 535
Query: 487 KGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAK 546
KG HCEL + C + C+N C C+C PGFTG C IDI++C S PC +G
Sbjct: 536 KGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGS 595
Query: 547 CIDHPNGYECQCATGFTGVLCE 568
C+D PNGY C C G+ G CE
Sbjct: 596 CLDQPNGYNCHCPHGWVGANCE 617
Score = 246 bits (629), Expect = 2e-64
Identities = 118/305 (38%), Positives = 166/305 (54%), Gaps = 13/305 (4%)
Query: 804 CLNQGTCFDDISG--YTCHCVLPYTGKNCQTVLAPCSPNPCENAAVC---KESPNFESYT 858
C +G C S ++C C Y G C+ A C PC+N A C E + ++T
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDA-CQRKPCQNNASCIDANEKQDGSNFT 377
Query: 859 CLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLAN 918
C+C PG+ G+ C ID CI PC N C ++ + C+CP G+ G CEE +D C ++
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437
Query: 919 PCQNGGSC-MDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQA 977
PCQN G+C +DGV+ F+C C PGFTG C ++ C PC +G TC SY C C
Sbjct: 438 PCQNNGTCYVDGVH-FTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTSYKCLCDP 495
Query: 978 GFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNE 1037
G+ G++CE NEC + C N TC D +N + C+C + G+ C + C++ CLN
Sbjct: 496 GYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNG 555
Query: 1038 GTC-VDGL-GTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAG 1095
TC DGL GT C C G+TG+ C +N C +PC + G+C+ + C CP GW G
Sbjct: 556 ATCDSDGLNGT--CICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVG 613
Query: 1096 AYCDV 1100
A C++
Sbjct: 614 ANCEI 618
Score = 245 bits (626), Expect = 3e-64
Identities = 112/292 (38%), Positives = 157/292 (53%), Gaps = 11/292 (3%)
Query: 590 SYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLV-----NGYQCNCQPGTSGVNCEI 644
+++C C Y+G C ++ D C PC N+ CID + + C C PG +G C+
Sbjct: 333 TFSCTCEEQYVGTFC-EEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQS 391
Query: 645 NFDDCASNPCIHGI-CMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC-INGVN 702
D C +PC +G C+ ++ ++C C G+ G C +D CAS+PC+ TC ++GV+
Sbjct: 392 KIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVH 451
Query: 703 GFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECL 762
F C C G P+C ++ C +PC HG C + YKCLCD G+ G+ CE + NECL
Sbjct: 452 -FTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECL 510
Query: 763 SNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCV 822
S PC N TC +LVNGY C C +KG +C++ D CA+ CLN TC D TC C
Sbjct: 511 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICA 570
Query: 823 LPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
+TG+ C + C NPC + C + PN Y C C GW G C I +
Sbjct: 571 PGFTGEECDIDINECDSNPCHHGGSCLDQPN--GYNCHCPHGWVGANCEIHL 620
Score = 243 bits (620), Expect = 2e-63
Identities = 117/309 (37%), Positives = 164/309 (53%), Gaps = 13/309 (4%)
Query: 732 GNCTGGLSG--YKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLV-----NGYRCTCK 784
G CT S + C C+ +VG CE + + C PCQN +C + + + C C
Sbjct: 323 GKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCL 381
Query: 785 KGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCEN 844
G+ G CQ ID C +PC N TC +SG+TC C Y G C+ + PC+ +PC+N
Sbjct: 382 PGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQN 441
Query: 845 AAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFS 904
C +TC C+PG+ G C ID C PC HG C + SY C C PG+
Sbjct: 442 NGTCYVDG--VHFTCNCSPGFTGPTCAQLIDFCALSPCA-HGTCRSVGTSYKCLCDPGYH 498
Query: 905 GMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTC 964
G+ CEE+ ++CL+ PC N +C D VN + C+CL + G C+ + C + C NG TC
Sbjct: 499 GLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATC 558
Query: 965 -SDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCL 1023
SD +N TC C GF G C+ +INEC + C +GG+C+D N ++C CP G+ G+ C
Sbjct: 559 DSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCE 617
Query: 1024 HEINECSSH 1032
+ S H
Sbjct: 618 IHLQWKSGH 626
Score = 236 bits (602), Expect = 2e-61
Identities = 120/305 (39%), Positives = 160/305 (52%), Gaps = 14/305 (4%)
Query: 115 CLNGGTCHML-SRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTV-----ANQFSC 168
C G C S T+ CTC+ + G C+ DAC PC N ++C + F+C
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTC 378
Query: 169 KCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPS 228
CL G+TG+ C++ ++ C I C++G TC++ + CQCP+G+ G C+ PCA S
Sbjct: 379 VCLPGYTGELCQSKIDYC-ILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437
Query: 229 PCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPP 288
PC N GTC G F CNC PGF G TC + ID C C + G C +Y C C P
Sbjct: 438 PCQNNGTCYVDG-VHFTCNCSPGFTGPTCAQLIDFCALSPCAH-GTCRSVGTSYKCLCDP 495
Query: 289 QWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCT 348
+ G +C E+ +ECL P C N TC + GY CVC+ + G C D CA SC
Sbjct: 496 GYHGLYCEEEYNECLSAP--CLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCL 553
Query: 349 PGSTCIDRVASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGY 407
G+TC + +C+C G G C +D + C SNPCH G C P NG Y C CP G+
Sbjct: 554 NGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQP-NG-YNCHCPHGW 611
Query: 408 KGADC 412
GA+C
Sbjct: 612 VGANC 616
Score = 233 bits (595), Expect = 1e-60
Identities = 115/328 (35%), Positives = 163/328 (49%), Gaps = 27/328 (8%)
Query: 958 CKNGGTCSDYVN--SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGI-----NSFS 1010
C G C+ + +++C C+ + G CE + C C N +C+D ++F+
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEE-YDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 1011 CLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRS 1070
C+C G+TG C +I+ C PC N TC+ L + C CP GY G C+ V+ C+ S
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437
Query: 1071 PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130
PC+N GTC C C G+ G C C ++ C H G C + G
Sbjct: 438 PCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSP----------CAH-GTCRSVG 486
Query: 1131 NTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDE 1190
++ C C GY G YCEE+ +EC S PC + ATC D + GY C C+ Y+G +CE D
Sbjct: 487 TSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDP 546
Query: 1191 CQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSC 1250
C N C NG TC + C C PG G C+ +I++C P C +GG C+D+ GY+C
Sbjct: 547 CANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNP-CHHGGSCLDQPNGYNC 605
Query: 1251 RCLPGFAGERCE-------GDINECLSN 1271
C G+ G CE G + E L+N
Sbjct: 606 HCPHGWVGANCEIHLQWKSGHMAESLTN 633
Score = 232 bits (592), Expect = 3e-60
Identities = 127/352 (36%), Positives = 168/352 (47%), Gaps = 60/352 (17%)
Query: 1072 CKNKGTCVQKKAES--QCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINA 1129
C KG C K +E+ C C + G +C+ + A R+ CQ++ CI+A
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYD-----ACQRKP------CQNNASCIDA 367
Query: 1130 -----GNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNC 1184
G+ C C GYTG C+ ++D C +PC++GATC + G+ C+C GY G C
Sbjct: 368 NEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSAC 427
Query: 1185 EYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDR 1244
E +VD C + PCQN GTC HF C+C PG G C + ID CA P C +G C
Sbjct: 428 EEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSP-CAHG-TCRSV 485
Query: 1245 IGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF 1304
Y C C PG+ G CE + NECLS PC + + C L N Y CVC + + G HCE +
Sbjct: 486 GTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAAT--CRDLVNGYECVCLAEYKGTHCELY 543
Query: 1305 VDVCPQMPCLNGGTCAVASNMPDGF--ICRCPPGFSGARCQSSCGQVKCRKGEQCVHTAS 1362
D C + CLNG TC DG C C PGF+G C +
Sbjct: 544 KDPCANVSCLNGATCD-----SDGLNGTCICAPGFTGEECDIDINE-------------- 584
Query: 1363 GPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELY 1414
C S+PC HGGSC QP Y+C C + G+ CE++
Sbjct: 585 ---------------CDSNPCHHGGSC--LDQPNGYNCHCPHGWVGANCEIH 619
Score = 231 bits (589), Expect = 7e-60
Identities = 113/313 (36%), Positives = 167/313 (53%), Gaps = 23/313 (7%)
Query: 920 CQNGGSCMDGVN--TFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYV-----NSYT 972
C G C + TFSC C + G C+ + + C +PC+N +C D +++T
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 973 CKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH 1032
C C G+ G C++ I+ C C NG TC+ ++ F+C CP G+ GS C +++ C+S
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437
Query: 1033 PCLNEGTC-VDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPS 1091
PC N GTC VDG+ + C+C G+TG C L++ C+ SPC + GTC +CLC
Sbjct: 438 PCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQLIDFCALSPCAH-GTCRSVGTSYKCLCDP 495
Query: 1092 GWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD 1151
G+ G YC+ C A C ++ C + N + C C Y G++CE D
Sbjct: 496 GYHGLYCEEEYNECLSAP----------CLNAATCRDLVNGYECVCLAEYKGTHCELYKD 545
Query: 1152 ECASNPCQHGATC-SDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210
CA+ C +GATC SD + G C C PG+ G C+ +++EC + PC +GG+C+D N +
Sbjct: 546 PCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYN 604
Query: 1211 CSCPPGTRGLLCE 1223
C CP G G CE
Sbjct: 605 CHCPHGWVGANCE 617
Score = 229 bits (583), Expect = 3e-59
Identities = 118/305 (38%), Positives = 160/305 (52%), Gaps = 16/305 (5%)
Query: 309 CQNGGTCANR--NGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRV-----ASFS 361
C G C + + C C + G C E D C C ++CID ++F+
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEE-YDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 362 CMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA 420
C+C G G LC D CI +PC GA C ++ L+G + C CP+GY G+ C E VD CA
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISS-LSG-FTCQCPEGYFGSACEEKVDPCA 435
Query: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC 480
S+PC++ G C F C C G+ GP C I+ C PC + TC + C
Sbjct: 436 ---SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAH-GTCRSVGTSYKC 491
Query: 481 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP 540
LC PG+ G++CE E NEC S PC+N C D VN ++C+C + G C++ D C++
Sbjct: 492 LCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVS 551
Query: 541 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDSYTCICNPGY 599
CLNGA C C CA GFTG C+ +I+ CD +PCHHG C D + Y C C G+
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGW 611
Query: 600 MGAIC 604
+GA C
Sbjct: 612 VGANC 616
Score = 226 bits (577), Expect = 2e-58
Identities = 114/312 (36%), Positives = 154/312 (49%), Gaps = 18/312 (5%)
Query: 230 CVNGGTCR-QTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGV-----NTYN 283
C G C + + TF C C + G+ CE D C CQN C+D + +
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEE-YDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 284 CRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCA 343
C C P +TG+ C +D C+L P C+NG TC + G+ C C G+ G C E +D CA
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDP--CRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCA 435
Query: 344 FASCTPGSTCIDRVASFSCMCPEGKAGLLC-HLDDACISNPCHKGALCDTNPLNGQYICT 402
+ C TC F+C C G G C L D C +PC G + Y C
Sbjct: 436 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTC---RSVGTSYKCL 492
Query: 403 CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHS 462
C GY G C E+ +EC A PC +A C + + C CL Y G CE+ + C +
Sbjct: 493 CDPGYHGLYCEEEYNECLSA---PCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCAN 549
Query: 463 DPCQNDATC-LDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCP 521
C N ATC D + G TC+C PGF G C+++INEC SNPC + G C+D+ N + C CP
Sbjct: 550 VSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCP 608
Query: 522 PGFTGPVCQIDI 533
G+ G C+I +
Sbjct: 609 HGWVGANCEIHL 620
Score = 224 bits (570), Expect = 1e-57
Identities = 115/307 (37%), Positives = 160/307 (52%), Gaps = 15/307 (4%)
Query: 35 CVNEGMCVTYHN-GTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCV---AQAMLGKATC 90
C +G C T + T C C E ++G +C+ D C++ CQN +C+ + TC
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTC 378
Query: 91 RCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACL 149
C G+TGE CQ + C + PC NG TC + S + C C G+ G C + D C
Sbjct: 379 VCLPGYTGELCQSKIDY-CILD-PCRNGATC-ISSLSGFTCQCPEGYFGSACEEKVDPCA 435
Query: 150 SHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC 209
S PC N TC F+C C GFTG C ++ C + C H GTC ++ SY+C C
Sbjct: 436 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCAL-SPCAH-GTCRSVGTSYKCLC 493
Query: 210 PQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRC 269
G+ G YC+ Y C +PC+N TCR + +EC CL ++G+ CE D C N C
Sbjct: 494 DPGYHGLYCEEEYNECLSAPCLNAATCRDLVN-GYECVCLAEYKGTHCELYKDPCANVSC 552
Query: 270 QNGGVC-VDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVN 328
NG C DG+N C C P +TG+ C D++EC N C +GG+C ++ GY C C +
Sbjct: 553 LNGATCDSDGLNG-TCICAPGFTGEECDIDINEC--DSNPCHHGGSCLDQPNGYNCHCPH 609
Query: 329 GWSGDDC 335
GW G +C
Sbjct: 610 GWVGANC 616
Score = 155 bits (391), Expect = 6e-37
Identities = 79/224 (35%), Positives = 107/224 (47%), Gaps = 42/224 (18%)
Query: 33 EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCR 91
+PC N C++ +G C+CPEG+ G C+ + DPC + CQN GTC + TC
Sbjct: 399 DPCRNGATCISSLSGFT-CQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGV--HFTCN 455
Query: 92 CASGFTGEDC------------------QYSTSHPCF-----------------VSRPCL 116
C+ GFTG C TS+ C +S PCL
Sbjct: 456 CSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCL 515
Query: 117 NGGTCHMLSRDTYECTCQVGFTGKECQ-WTDACLSHPCANGSTCTTVANQFSCKCLTGFT 175
N TC L YEC C + G C+ + D C + C NG+TC + +C C GFT
Sbjct: 516 NAATCRDLVNG-YECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFT 574
Query: 176 GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCD 219
G++C+ D+NECD C HGG+CL+ P Y C CP G+ G C+
Sbjct: 575 GEECDIDINECD-SNPCHHGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 137 bits (344), Expect = 2e-31
Identities = 103/326 (31%), Positives = 132/326 (40%), Gaps = 55/326 (16%)
Query: 1175 CVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNH--FKCSCPPGTRGLLCEENIDDCARG 1232
CVPG N + C G C + F C+C G CEE D C R
Sbjct: 307 CVPGESHAN---------DLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEE-YDACQRK 356
Query: 1233 PHCLNGGQCMDRI-----GGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTND 1287
P C N C+D ++C CLPG+ GE C+ I+ C+ +PC + + CI +
Sbjct: 357 P-CQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGAT--CISSLSG 413
Query: 1288 YLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDG--FICRCPPGFSGARCQSS 1345
+ C C + G CE VD C PC N GTC V DG F C C PGF+G C
Sbjct: 414 FTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYV-----DGVHFTCNCSPGFTGPTCAQL 468
Query: 1346 ---CGQVKCRKGEQCVHTASGPRCFCPSPRD---CE---SGCASSPCQHGGSCHPQRQPP 1396
C C G C + +C C CE + C S+PC + +C
Sbjct: 469 IDFCALSPCAHGT-CRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNG- 526
Query: 1397 YYSCQCAPPFSGSRCELYTAPPSTPP----ATCLSQ------YCADKARDGVCD---EAC 1443
Y C C + G+ CELY P + ATC S CA CD C
Sbjct: 527 -YECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINEC 585
Query: 1444 NSHACQWDGGDCSLTMENPWANCSSP 1469
+S+ C GG C L N + NC P
Sbjct: 586 DSNPCH-HGGSC-LDQPNGY-NCHCP 608
Score = 70.9 bits (172), Expect = 2e-11
Identities = 33/86 (38%), Positives = 42/86 (48%), Gaps = 16/86 (18%)
Query: 686 CASNPCRKGATCIN------------GVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN 733
CA+ PCR G C + G G+ C CP G +C + C SNPC HGN
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 734 CTGGLS----GYKCLCDAGWVGINCE 755
C+ S GY C+C+ G+ G NCE
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 69.7 bits (169), Expect = 3e-11
Identities = 36/90 (40%), Positives = 42/90 (46%), Gaps = 17/90 (18%)
Query: 761 CLSNPCQNGGTCDNLVN------------GYRCTCKKGFKGYNCQVNIDECASNPCLNQG 808
C + PC+NGG C + GY CTC G G NCQ+ D CASNPC + G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPC-HHG 106
Query: 809 TCFDDIS----GYTCHCVLPYTGKNCQTVL 834
C S GY C C Y G NC+ L
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 63.9 bits (154), Expect = 2e-09
Identities = 33/81 (40%), Positives = 42/81 (51%), Gaps = 15/81 (18%)
Query: 1120 CQHSGVCIN-----------AGNTHY-CQCPLGYTGSYCEEQLDECASNPCQHG---ATC 1164
C++ GVC + AG Y C CP G +G+ C+ D CASNPC HG ++
Sbjct: 53 CRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSS 112
Query: 1165 SDFIGGYRCECVPGYQGVNCE 1185
S GY C C GY+G NCE
Sbjct: 113 SSSSDGYLCICNEGYEGPNCE 133
Score = 63.5 bits (153), Expect = 2e-09
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 15/89 (16%)
Query: 836 PCSPNPCENAAVCKESPNFE----------SYTCLCAPGWQGQRCTIDIDECISKPCMNH 885
PC+ PC N VC P + Y+C C G G C + D C S PC +H
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPC-HH 105
Query: 886 GLCHNTQGS----YMCECPPGFSGMDCEE 910
G C ++ S Y+C C G+ G +CE+
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 59.7 bits (143), Expect = 3e-08
Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 15/86 (17%)
Query: 915 CLANPCQNGGSCMD------------GVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGG 962
C A PC+NGG C G +SC C G +G CQ + C S PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 963 TCSDYVNS---YTCKCQAGFDGVHCE 985
S +S Y C C G++G +CE
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 59.3 bits (142), Expect = 5e-08
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 13/85 (15%)
Query: 799 CASNPCLNQGTCFDDIS------------GYTCHCVLPYTGKNCQTVLAPCSPNPCENA- 845
CA+ PC N G C GY+C C +G NCQ V PC+ NPC +
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 846 AVCKESPNFESYTCLCAPGWQGQRC 870
S + + Y C+C G++G C
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 58.2 bits (139), Expect = 1e-07
Identities = 30/85 (35%), Positives = 41/85 (48%), Gaps = 16/85 (18%)
Query: 649 CASNPCIHG-ICMD------------GINRYSCVCSPGFTGQRCNIDIDECASNPCRKG- 694
CA+ PC +G +C G YSC C G +G C + D CASNPC G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 695 --ATCINGVNGFRCICPEGPHHPSC 717
++ + +G+ CIC EG P+C
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 57.8 bits (138), Expect = 1e-07
Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 15/86 (17%)
Query: 877 CISKPCMNHGLCHNT------------QGSYMCECPPGFSGMDCEEDIDDCLANPCQNG- 923
C ++PC N G+C + + Y C CP G SG +C+ D C +NPC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 924 --GSCMDGVNTFSCLCLPGFTGDKCQ 947
S + + C+C G+ G C+
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 57.0 bits (136), Expect = 2e-07
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 17/87 (19%)
Query: 1029 CSSHPCLNEGTCVD------------GLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKG 1076
C++ PC N G C G Y C+CP G +G NCQ + + C+ +PC + G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPC-HHG 106
Query: 1077 TCVQKKAESQ----CLCPSGWAGAYCD 1099
C + S C+C G+ G C+
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 54.7 bits (130), Expect = 1e-06
Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 14/94 (14%)
Query: 1229 CARGPHCLNGGQCMDRIG------------GYSCRCLPGFAGERCEGDINECLSNPCSSE 1276
CA P C NGG C R GYSC C G +G C+ + C SNPC
Sbjct: 48 CAAQP-CRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHG 106
Query: 1277 GSLDCIQLTND-YLCVCRSAFTGRHCETFVDVCP 1309
++D YLC+C + G +CE + P
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLP 140
Score = 53.9 bits (128), Expect = 2e-06
Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 16/92 (17%)
Query: 104 STSHPCFVSRPCLNGGTCHM-----------LSRDTYECTCQVGFTGKECQW-TDACLSH 151
S PC ++PC NGG C Y CTC G +G CQ D C S+
Sbjct: 43 SAPGPC-AAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASN 101
Query: 152 PCANG---STCTTVANQFSCKCLTGFTGQKCE 180
PC +G S+ ++ ++ + C C G+ G CE
Sbjct: 102 PCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 53.9 bits (128), Expect = 2e-06
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 17/87 (19%)
Query: 991 CTESSCFNGGTCVD------------GINSFSCLCPVGFTGSFCLHEINECSSHPCLNEG 1038
C C NGG C G +SC CP G +G+ C + C+S+PC + G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPC-HHG 106
Query: 1039 TCVDGLGT----YRCSCPLGYTGKNCQ 1061
C + Y C C GY G NC+
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 52.4 bits (124), Expect = 6e-06
Identities = 18/58 (31%), Positives = 31/58 (53%)
Query: 1288 YLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS 1345
Y C C + +G +C+ D C PC +G + +S+ DG++C C G+ G C+ +
Sbjct: 78 YSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQA 135
Score = 50.8 bits (120), Expect = 2e-05
Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 15/85 (17%)
Query: 953 CLSEPCKNGGTCSDYVN------------SYTCKCQAGFDGVHCENNINECTESSCFNGG 1000
C ++PC+NGG C+ Y+C C AG G +C+ + C + C +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 1001 TCVDGINS---FSCLCPVGFTGSFC 1022
+S + C+C G+ G C
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 50.4 bits (119), Expect = 2e-05
Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 14/89 (15%)
Query: 67 PCEKNRCQNGGTCVAQ--------AMLGKA--TCRCASGFTGEDCQYSTSHPCFVSRPCL 116
PC C+NGG C ++ A G+ +C C +G +G +CQ + PC S PC
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL-VADPC-ASNPCH 104
Query: 117 NG--GTCHMLSRDTYECTCQVGFTGKECQ 143
+G + S D Y C C G+ G C+
Sbjct: 105 HGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 50.1 bits (118), Expect = 3e-05
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 15/87 (17%)
Query: 1153 CASNPCQHGATCSDFIG------------GYRCECVPGYQGVNCEYEVDECQNQPCQNG- 1199
CA+ PC++G C+ GY C C G G NC+ D C + PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 1200 --GTCIDLVNHFKCSCPPGTRGLLCEE 1224
+ + + C C G G CE+
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 49.7 bits (117), Expect = 4e-05
Identities = 28/87 (32%), Positives = 34/87 (39%), Gaps = 16/87 (18%)
Query: 1191 CQNQPCQNGGTCIDLVNH------------FKCSCPPGTRGLLCEENIDDCARGPHCLNG 1238
C QPC+NGG C + C+CP G G C+ D CA P C +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNP-CHHG 106
Query: 1239 ---GQCMDRIGGYSCRCLPGFAGERCE 1262
GY C C G+ G CE
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 48.9 bits (115), Expect = 6e-05
Identities = 38/125 (30%), Positives = 42/125 (33%), Gaps = 43/125 (34%)
Query: 1308 CPQMPCLNGGTCAVASNMPD----------GFICRCPPGFSGARCQSSCGQVKCRKGEQC 1357
C PC NGG C PD G+ C CP G SGA CQ
Sbjct: 48 CAAQPCRNGGVCTSRPE-PDPQHPAPAGEPGYSCTCPAGISGANCQ-------------- 92
Query: 1358 VHTASGPRCFCPSPRDCESGCASSPCQHGG-SCHPQRQPPYYSCQCAPPFSGSRCELYTA 1416
+ P CAS+PC HG S Y C C + G CE A
Sbjct: 93 --LVADP-------------CASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE--QA 135
Query: 1417 PPSTP 1421
PS P
Sbjct: 136 LPSLP 140
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 14/88 (15%)
Query: 224 PCAPSPCVNGGTCRQ-----------TGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNG 272
PCA PC NGG C G+ + C C G G+ C+ D C ++ C +G
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHG 106
Query: 273 GVCVDGVNT---YNCRCPPQWTGQFCTE 297
++ Y C C + G C +
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 46.6 bits (109), Expect = 3e-04
Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 24/112 (21%)
Query: 1370 SPRDCESGCASSPCQHGGSCHPQRQP----------PYYSCQCAPPFSGSRCELYTAPPS 1419
+P CA+ PC++GG C + +P P YSC C SG+ C+L P
Sbjct: 40 APLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADP-- 97
Query: 1420 TPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLP 1471
C S C G C + +S + DG C NC LP
Sbjct: 98 -----CASNPC----HHGNCSSSSSSSS---DGYLCICNEGYEGPNCEQALP 137
Score = 42.0 bits (97), Expect = 0.007
Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 13/83 (15%)
Query: 33 EPCVNEGMCVTYHNGT----------GY-CKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCV 80
+PC N G+C + GY C CP G G CQ DPC N C +G
Sbjct: 51 QPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSS 110
Query: 81 AQAMLGKA-TCRCASGFTGEDCQ 102
+ + C C G+ G +C+
Sbjct: 111 SSSSSSDGYLCICNEGYEGPNCE 133
Score = 41.6 bits (96), Expect = 0.010
Identities = 26/100 (26%), Positives = 39/100 (39%), Gaps = 27/100 (27%)
Query: 1067 CSRSPCKNKGTCVQKKAES------------QCLCPSGWAGAYCDVPNVSCDIAASRRGV 1114
C+ PC+N G C + C CP+G +GA C + C
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPC--------- 98
Query: 1115 LVEHLCQHSGVCINAGNT----HYCQCPLGYTGSYCEEQL 1150
+ C H G C ++ ++ + C C GY G CE+ L
Sbjct: 99 -ASNPCHH-GNCSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 38.9 bits (89), Expect = 0.063
Identities = 43/164 (26%), Positives = 55/164 (33%), Gaps = 20/164 (12%)
Query: 1375 ESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKA 1434
ES C G C + +SC C + G+ CE Y A P S A++
Sbjct: 311 ESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEK 370
Query: 1435 RDG-----VCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCW------DYINNQCDEL 1483
+DG VC CQ C L A C S L + Y + C+E
Sbjct: 371 QDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEK 430
Query: 1484 CNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEEC 1527
+ + CQ N TC D HF N C G C
Sbjct: 431 VDPCA----SSPCQNNG-TCYVD---GVHFTCN-CSPGFTGPTC 465
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 277 bits (709), Expect = 8e-74
Identities = 252/852 (29%), Positives = 338/852 (39%), Gaps = 228/852 (26%)
Query: 91 RCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----- 143
+C GF +GE C + C R C+ TC C+ G+ G C
Sbjct: 93 QCCPGFYESGEMCVPHCADKCVHGR-CIAPNTCQ----------CEPGWGGTNCSSACDG 141
Query: 144 --WTDACLSH-PCANGSTCTTVANQFSCKCLTGFTGQKCE------TDVNECDIPGHCQH 194
W C S C NG+ C + +C C GF G +CE T N+C CQ+
Sbjct: 142 DHWGPHCTSRCQCKNGALCNPITG--ACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQN 199
Query: 195 GGTCLNLPGSYQCQCPQGFTGQYCDSLYVP------CAP-SPCVNGGTCRQTGDFTFECN 247
G TC ++ G +C+CP G+TG +C+ L P C PC NGG C T EC+
Sbjct: 200 GATCDHVTG--ECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHV---TGECS 254
Query: 248 CLPGFEGSTCERNIDDCPNHR----------CQNGGVCVDGVNTYNCRCPPQWTGQFCTE 297
C G+ G+ C + CP R C NGG C T C C P +TG+ C
Sbjct: 255 CPSGWMGTVCGQ---PCPEGRFGKNCSQECQCHNGGTC--DAATGQCHCSPGYTGERCQ- 308
Query: 298 DVDEC------LLQPNACQ--NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTP 349
DEC +L CQ NGG C + +G C+C G++G+ C
Sbjct: 309 --DECPVGTYGVLCAETCQCVNGGKCYHVSG--ACLCEAGFAGERCEAR----------- 353
Query: 350 GSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKG 409
+CPEG G+ C D C PCH +P++G+ C C G+ G
Sbjct: 354 -------------LCPEGLYGIKC--DKRC---PCHLENTHSCHPMSGE--CACKPGWSG 393
Query: 410 ADCTEDV------DECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE-------MD 456
C E + C S C++ C + G C C G+ G C
Sbjct: 394 LYCNETCSPGFYGEACQQICS--CQNGADCDSVTG--KCTCAPGFKGIDCSTPCPLGTYG 449
Query: 457 INECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSN----------PCVNN 506
IN C+NDA C G +C C G+ GV C + C S C+N
Sbjct: 450 INCSSRCGCKNDAVCSPVDG--SCTCKAGWHGVDCSI---RCPSGTWGFGCNLTCQCLNG 504
Query: 507 GQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCID-------HPNGYECQCA 559
G C C C PG+ G C++ D T LN A+ D HP C+C
Sbjct: 505 GAC--NTLDGTCTCAPGWRGEKCELPCQD--GTYGLNCAERCDCSHADGCHPTTGHCRCL 560
Query: 560 TGFTGVLCE------------------ENIDNCDPDP--CHHGQCQDGIDSYTC--ICNP 597
G++GV C+ +N +C PD C +C G TC IC+P
Sbjct: 561 PGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC---ECAPGFRGTTCQRICSP 617
Query: 598 GYMGAICSDQIDECY--SSPCLNDGRCIDLVNGYQ---CN--CQPGTSGVNCEINFDDCA 650
G+ G CS +C S PC + D + G+ CN C G G NC C
Sbjct: 618 GFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNC-AGICTCT 676
Query: 651 SNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPE 710
+N G C + I+R SC C PG+ G C+ C P G CI+ C C
Sbjct: 677 NN----GTC-NPIDR-SCQCYPGWIGSDCS---QPCP--PAHWGPNCIH-----TCNCHN 720
Query: 711 GPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCL--CDAGWVGINCEVDKNECLSNPCQN 768
G C + EC CT G +G C C G+ G +C L CQN
Sbjct: 721 GAF---CSAYDGEC--------KCTPGWTGLYCTQRCPLGFYGKDC------ALICQCQN 763
Query: 769 GGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASN----------PCLNQGTCFDDISGYT 818
G CD++ +CTC+ GF G +C+ +C S CLN TC D I+G T
Sbjct: 764 GADCDHISG--QCTCRTGFMGRHCE---QKCPSGTYGYGCRQICDCLNNSTC-DHITG-T 816
Query: 819 CHCVLPYTGKNC 830
C+C + G C
Sbjct: 817 CYCSPGWKGARC 828
Score = 267 bits (683), Expect = 8e-71
Identities = 269/943 (28%), Positives = 357/943 (37%), Gaps = 291/943 (30%)
Query: 403 CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHS 462
CP Y+ + V CA + C H G+C+ + C+C G+ G C + H
Sbjct: 95 CPGFYESGEMC--VPHCA----DKCVH-GRCIAPNT---CQCEPGWGGTNCSSACDGDHW 144
Query: 463 DP-------CQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNR 515
P C+N A C G C C GF+G +C D+
Sbjct: 145 GPHCTSRCQCKNGALCNPITGA--CHCAAGFRG------------------WRCEDR--- 181
Query: 516 FQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCD 575
C G G C C NGA C DH G EC+C G+TG CE D C
Sbjct: 182 ----CEQGTYGNDCH------QRCQCQNGATC-DHVTG-ECRCPPGYTGAFCE---DLCP 226
Query: 576 PDPCHHGQCQD-------GIDSYT---CICNPGYMGAICSDQIDE-------CYSSPCLN 618
P H QC+ G+ + C C G+MG +C E C N
Sbjct: 227 PGK-HGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHN 285
Query: 619 DGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-------CMDGINRY----S 667
G C D G QC+C PG +G C+ D+C +G+ C++G Y +
Sbjct: 286 GGTC-DAATG-QCHCSPGYTGERCQ---DECPVGT--YGVLCAETCQCVNGGKCYHVSGA 338
Query: 668 CVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCI--CP---EGPHHPSCYSQVN 722
C+C GF G+RC + C G+ G +C CP E H SC+
Sbjct: 339 CLCEAGFAGERCEARL-------------CPEGLYGIKCDKRCPCHLENTH--SCHPMSG 383
Query: 723 ECLSNPCIHGNCTGGLSGYKC--LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780
EC P G SG C C G+ G C+ C CQNG CD++ +
Sbjct: 384 ECACKP--------GWSGLYCNETCSPGFYGEACQ---QIC---SCQNGADCDSVTG--K 427
Query: 781 CTCKKGFKGYNCQVNID------ECASN-PCLNQGTCFDDISGYTCHCVLPYTGKNCQTV 833
CTC GFKG +C C+S C N C + G +C C + G +C ++
Sbjct: 428 CTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVC-SPVDG-SCTCKAGWHGVDC-SI 484
Query: 834 LAP-------CSPN-PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDE------CIS 879
P C+ C N C N TC CAPGW+G++C + + C
Sbjct: 485 RCPSGTWGFGCNLTCQCLNGGAC----NTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE 540
Query: 880 K-PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP-------CQNGGSCM--DG 929
+ C + CH T G C C PG+SG+ C+ + P C+NG SC DG
Sbjct: 541 RCDCSHADGCHPTTGH--CRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDG 598
Query: 930 VNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNIN 989
+ C C PGF G CQ C GF G C
Sbjct: 599 I----CECAPGFRGTTCQR-------------------------ICSPGFYGHRCSQTCP 629
Query: 990 ECTESSCFNGGTC--VDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTY 1047
+C SS G C + G+ C C GFTG+ C NE
Sbjct: 630 QCVHSS----GPCHHITGL----CDCLPGFTGALC----NEV------------------ 659
Query: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDI 1107
CP G GKNC +C+ C N GTC + C C GW G+ C P
Sbjct: 660 ---CPSGRFGKNC---AGICT---CTNNGTC--NPIDRSCQCYPGWIGSDCSQP-----C 703
Query: 1108 AASRRGVLVEHLCQ-HSGVCINAGNTHYCQCPLGYTGSYCEEQL------DECA-SNPCQ 1159
+ G H C H+G +A + C+C G+TG YC ++ +CA CQ
Sbjct: 704 PPAHWGPNCIHTCNCHNGAFCSAYDGE-CKCTPGWTGLYCTQRCPLGFYGKDCALICQCQ 762
Query: 1160 HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRG 1219
+GA C D I G +C C G+ G +CE + CP GT G
Sbjct: 763 NGADC-DHISG-QCTCRTGFMGRHCEQK-------------------------CPSGTYG 795
Query: 1220 LLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE 1262
C + D CLN C D I G +C C PG+ G RC+
Sbjct: 796 YGCRQICD-------CLNNSTC-DHITG-TCYCSPGWKGARCD 829
Score = 252 bits (644), Expect = 3e-66
Identities = 235/851 (27%), Positives = 323/851 (37%), Gaps = 232/851 (27%)
Query: 368 KAGLLC--HLDDACISNPCHKGALCDTNPLNGQYICT--CPQGYKGADCTEDVDECAMAN 423
++G +C H D C+ C C P G C+ C + G CT
Sbjct: 100 ESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQ------ 153
Query: 424 SNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI------NECHSD-PCQNDATCLDKIG 476
C++ C GA C C G+ G RCE N+CH CQN ATC D +
Sbjct: 154 ---CKNGALCNPITGA--CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC-DHVT 207
Query: 477 GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC 536
G C C PG+ G CE LCPPG GP C+
Sbjct: 208 G-ECRCPPGYTGAFCE-------------------------DLCPPGKHGPQCE------ 235
Query: 537 SSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENID------NCDPD-PCHHGQCQDGID 589
PC NG C H G EC C +G+ G +C + NC + CH+G D
Sbjct: 236 QRCPCQNGGVC-HHVTG-ECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAAT 293
Query: 590 SYTCICNPGYMGAICSDQIDE-------CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNC 642
C C+PGY G C D+ + C+N G+C + C C+ G +G C
Sbjct: 294 GQ-CHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGA--CLCEAGFAGERC 350
Query: 643 EINFDDCASNPCIHGICMDGI------NRYSC-------VCSPGFTGQRCNIDIDECASN 689
E C ++GI D N +SC C PG++G CN + C+
Sbjct: 351 EARL--CPEG--LYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCN---ETCSPG 403
Query: 690 ----------PCRKGA---------TCINGVNGFRCI--CPEGPHHPSCYSQV---NECL 725
C+ GA TC G G C CP G + +C S+ N+ +
Sbjct: 404 FYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAV 463
Query: 726 SNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC----------LSNPCQNGGTCDNL 775
+P + G+CT C AGW G++C + C L+ C NGG C+ L
Sbjct: 464 CSP-VDGSCT---------CKAGWHGVDCSI---RCPSGTWGFGCNLTCQCLNGGACNTL 510
Query: 776 VNGYRCTCKKGFKGYNCQVNIDE------CASNPCLNQGTCFDDISGYTCHCVLPYTGKN 829
CTC G++G C++ + CA + +G+ C C+ ++G +
Sbjct: 511 DG--TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGH-CRCLPGWSGVH 567
Query: 830 CQTVLAP------CS-PNPCENAA-------VCKESPNFESYTC--LCAPGWQGQRCTID 873
C +V A CS P C+N A +C+ +P F TC +C+PG+ G RC+
Sbjct: 568 CDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQT 627
Query: 874 IDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDID------DCLAN-PCQNGGSC 926
+C+ + G CH+ G +C+C PGF+G C E +C C N G+C
Sbjct: 628 CPQCVH----SSGPCHHITG--LCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTC 681
Query: 927 MDGVNTFSCLCLPGFTGDKCQTDMNECLSEP-------CKNGGTCSDYVNSYTCKCQAGF 979
SC C PG+ G C P C NG CS Y CKC G+
Sbjct: 682 --NPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE--CKCTPGW 737
Query: 980 DGVHCENNI------NECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH 1032
G++C +C C NG C D I+ C C GF G C +
Sbjct: 738 TGLYCTQRCPLGFYGKDCALICQCQNGADC-DHISG-QCTCRTGFMGRHCEQK------- 788
Query: 1033 PCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSG 1092
CP G G C+ + + C N TC C C G
Sbjct: 789 ------------------CPSGTYGYGCRQICD------CLNNSTC--DHITGTCYCSPG 822
Query: 1093 WAGAYCDVPNV 1103
W GA CD V
Sbjct: 823 WKGARCDQAGV 833
Score = 250 bits (639), Expect = 1e-65
Identities = 222/803 (27%), Positives = 305/803 (37%), Gaps = 174/803 (21%)
Query: 715 PSCYSQVNECL---SNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKN------ECLSN- 764
P Y C+ ++ C+HG C ++ C C+ GW G NC + C S
Sbjct: 96 PGFYESGEMCVPHCADKCVHGRC---IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRC 152
Query: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLP 824
C+NG C+ + C C GF+G+ C+ D C QGT +D C C
Sbjct: 153 QCKNGALCNPITGA--CHCAAGFRGWRCE---DRC------EQGTYGNDCH-QRCQC--- 197
Query: 825 YTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMN 884
G C V C P A C++ LC PG G +C C PC N
Sbjct: 198 QNGATCDHVTGECRCPPGYTGAFCED---------LCPPGKHGPQCE---QRC---PCQN 242
Query: 885 HGLCHNTQGSYMCECPPGFSGMDCEEDIDD------CLAN-PCQNGGSCMDGVNTFSCLC 937
G+CH+ G C CP G+ G C + + C C NGG+C T C C
Sbjct: 243 GGVCHHVTGE--CSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTC--DAATGQCHC 298
Query: 938 LPGFTGDKCQTDMNEC--------LSEPCK--NGGTCSDYVNSYTCKCQAGFDGVHCENN 987
PG+TG++CQ +EC +E C+ NGG C Y S C C+AGF G CE
Sbjct: 299 SPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKC--YHVSGACLCEAGFAGERCEAR 353
Query: 988 INECTES----------SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSS-----H 1032
+ C E C T S C C G++G +C NE S
Sbjct: 354 L--CPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYC----NETCSPGFYGE 407
Query: 1033 PCLNEGTCVDGLG----TYRCSCPLGYTGKNCQTL-------VNLCSRSPCKNKGTCVQK 1081
C +C +G T +C+C G+ G +C T +N SR CKN C
Sbjct: 408 ACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVC--S 465
Query: 1082 KAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY 1141
+ C C +GW G C ++ C G + C + G C T C C G+
Sbjct: 466 PVDGSCTCKAGWHGVDC---SIRCPSGTWGFGCNLTCQCLNGGACNTLDGT--CTCAPGW 520
Query: 1142 TGSYCEEQLDE------CASN-PCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQ 1194
G CE + CA C H C G C C+PG+ GV+C+ E +
Sbjct: 521 RGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG--HCRCLPGWSGVHCDSVCAEGRWG 578
Query: 1195 P-------CQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARG-------PHCLNGGQ 1240
P C+NG +C + C C PG RG C+ G P C++
Sbjct: 579 PNCSLPCYCKNGASCSP--DDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSG 636
Query: 1241 CMDRIGGYSCRCLPGFAGERCE-----GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSA 1295
I G C CLPGF G C G + + C+ + C + D C C
Sbjct: 637 PCHHITGL-CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPI--DRSCQCYPG 693
Query: 1296 FTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFIC-------RCPPGFSGARCQSSCGQ 1348
+ G C CP P G C N +G C +C PG++G C C
Sbjct: 694 WIGSDCS---QPCP--PAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPL 748
Query: 1349 ----------VKCRKGEQCVHTASGPRCFCPSP---RDCESGCASSP----CQHGGSCHP 1391
+C+ G C H + +C C + R CE C S C+ C
Sbjct: 749 GFYGKDCALICQCQNGADCDHISG--QCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLN 806
Query: 1392 QRQPPYYS--CQCAPPFSGSRCE 1412
+ + C C+P + G+RC+
Sbjct: 807 NSTCDHITGTCYCSPGWKGARCD 829
Score = 242 bits (617), Expect = 4e-63
Identities = 227/807 (28%), Positives = 307/807 (38%), Gaps = 217/807 (26%)
Query: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR--------DPCEKNRCQNGGTCVAQAMLG 86
C N +C TG C C GF G C+ R D ++ +CQNG TC + G
Sbjct: 154 CKNGALCNPI---TGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC--DHVTG 208
Query: 87 KATCRCASGFTGEDCQ-----YSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE 141
+ CRC G+TG C+ C PC NGG CH + T EC+C G+ G
Sbjct: 209 E--CRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHV---TGECSCPSGWMGTV 263
Query: 142 C-------QWTDACLSH-PCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGH-- 191
C ++ C C NG TC Q C C G+TG++C+ +EC + +
Sbjct: 264 CGQPCPEGRFGKNCSQECQCHNGGTCDAATGQ--CHCSPGYTGERCQ---DECPVGTYGV 318
Query: 192 -------CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTF 244
C +GG C ++ G+ C C GF G+ C++
Sbjct: 319 LCAETCQCVNGGKCYHVSGA--CLCEAGFAGERCEARL---------------------- 354
Query: 245 ECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD---- 300
C G G C++ CP H +N C + C C P W+G +C E
Sbjct: 355 ---CPEGLYGIKCDKR---CPCH-LENTHSC--HPMSGECACKPGWSGLYCNETCSPGFY 405
Query: 301 -ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSE-------NIDDCAFASCTPGST 352
E Q +CQNG C + G C C G+ G DCS I+ + C +
Sbjct: 406 GEACQQICSCQNGADCDSVTG--KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAV 463
Query: 353 CIDRVASFSC-----------MCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYIC 401
C S +C CP G G C+L C++ G C+T L+G C
Sbjct: 464 CSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLN-----GGACNT--LDG--TC 514
Query: 402 TCPQGYKGADCTEDVDE----CAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI 457
TC G++G C + A C HA C T G HC CL G++G C+
Sbjct: 515 TCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG--HCRCLPGWSGVHCDSVC 572
Query: 458 NECHSDP-------CQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCV 510
E P C+N A+C G C C PGF+G C
Sbjct: 573 AEGRWGPNCSLPCYCKNGASCSPDDG--ICECAPGFRGTTC------------------- 611
Query: 511 DKVNRFQCLCPPGFTGPVCQIDIDDC--SSTPCLNGAKCIDHPNGYECQCATGFTGVLCE 568
Q +C PGF G C C SS PC H G C C GFTG LC
Sbjct: 612 ------QRICSPGFYGHRCSQTCPQCVHSSGPC-------HHITGL-CDCLPGFTGALCN 657
Query: 569 ENI------DNC-DPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP-CLNDG 620
E NC C + + ID +C C PG++G+ CS + P C++
Sbjct: 658 EVCPSGRFGKNCAGICTCTNNGTCNPIDR-SCQCYPGWIGSDCSQPCPPAHWGPNCIHTC 716
Query: 621 RCID--LVNGY--QCNCQPGTSGV----NCEINF--DDCA-SNPCIHGICMDGINRYSCV 669
C + + Y +C C PG +G+ C + F DCA C +G D I+ C
Sbjct: 717 NCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISG-QCT 775
Query: 670 CSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSN-P 728
C GF G+ C C +G G+ C Q+ +CL+N
Sbjct: 776 CRTGFMGRHCE--------------QKCPSGTYGYGC------------RQICDCLNNST 809
Query: 729 CIHGNCTGGLSGYKCLCDAGWVGINCE 755
C H TG C C GW G C+
Sbjct: 810 CDH--ITG-----TCYCSPGWKGARCD 829
Score = 231 bits (588), Expect = 9e-60
Identities = 222/778 (28%), Positives = 302/778 (38%), Gaps = 184/778 (23%)
Query: 861 CAPGW--QGQRCTIDIDECISKPCMNHGLC--HNTQGSYMCECPPGFSGMDCEEDIDDCL 916
C PG+ G+ C + C K C+ HG C NT C+C PG+ G +C D
Sbjct: 94 CCPGFYESGEMC---VPHCADK-CV-HGRCIAPNT-----CQCEPGWGGTNCSSACDGDH 143
Query: 917 ANP-------CQNGGSCMDGVNTFSCLCLPGFTGDKCQ------TDMNECLSE-PCKNGG 962
P C+NG C T +C C GF G +C+ T N+C C+NG
Sbjct: 144 WGPHCTSRCQCKNGALC--NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGA 201
Query: 963 TCSDYVNSYTCKCQAGFDGVHCEN------NINECTESS-CFNGGTC--VDGINSFSCLC 1013
TC D+V C+C G+ G CE+ + +C + C NGG C V G C C
Sbjct: 202 TC-DHVTG-ECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTG----ECSC 255
Query: 1014 PVGFTGSFCLHEINE------CSSH-PCLNEGTCVDGLGTYRCSCPLGYTGKNCQ----- 1061
P G+ G+ C E CS C N GTC G +C C GYTG+ CQ
Sbjct: 256 PSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATG--QCHCSPGYTGERCQDECPV 313
Query: 1062 -TLVNLCSRS-PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHL 1119
T LC+ + C N G C CLC +G+AG C+ + G+ +
Sbjct: 314 GTYGVLCAETCQCVNGGKCYH--VSGACLCEAGFAGERCEARLCPEGLY----GIKCDKR 367
Query: 1120 CQHSGVCINAGNTHYCQ-------CPLGYTGSYCEEQL------DECASN-PCQHGATCS 1165
C + NTH C C G++G YC E + C CQ+GA C
Sbjct: 368 CP-----CHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCD 422
Query: 1166 DFIGGYRCECVPGYQGVNCE-------YEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR 1218
G +C C PG++G++C Y ++ C+N C + C+C G
Sbjct: 423 SVTG--KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDG--SCTCKAGWH 478
Query: 1219 GLLCEENIDD------CARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE-----GDINE 1267
G+ C C CLNGG C G +C C PG+ GE+CE G
Sbjct: 479 GVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDG--TCTCAPGWRGEKCELPCQDGTYGL 536
Query: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQ--------MPCL--NGG 1317
+ C + C T C C ++G HC++ VC + +PC NG
Sbjct: 537 NCAERCDCSHADGCHPTTGH--CRCLPGWSGVHCDS---VCAEGRWGPNCSLPCYCKNGA 591
Query: 1318 TCAVASNMPDGFICRCPPGFSGARCQSSC-----GQVKCRKGEQCVHTA----------- 1361
+C+ PD IC C PGF G CQ C G + QCVH++
Sbjct: 592 SCS-----PDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCD 646
Query: 1362 -----SGPRC--FCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELY 1414
+G C CPS R ++ C + G+C+P + SCQC P + GS C
Sbjct: 647 CLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDR----SCQCYPGWIGSDC--- 699
Query: 1415 TAPPSTPPATCLSQYCADKARDGVCDEACNSH---ACQWDGGDCSLTMENPWANCSSPLP 1471
SQ C C CN H C G+C T C+ P
Sbjct: 700 ------------SQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCP 747
Query: 1472 CWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEECGW 1529
Y C +C +C + +C S C C F HC+Q C S G+
Sbjct: 748 LGFY-GKDCALIC---QCQ-NGADCDHISGQCT----CRTGFMGRHCEQKCPSGTYGY 796
Score = 222 bits (565), Expect = 4e-57
Identities = 212/739 (28%), Positives = 284/739 (38%), Gaps = 192/739 (25%)
Query: 19 CAAPAHALQCRDGYEP------CVNEGMC---VTYHNGTGYCKCPEGFLGEYCQ------ 63
CAA +C D E C C T + TG C+CP G+ G +C+
Sbjct: 169 CAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPG 228
Query: 64 -HRDPCEKN-RCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR-------- 113
H CE+ CQNGG C + G+ C C SG+ G C PC R
Sbjct: 229 KHGPQCEQRCPCQNGGVC--HHVTGE--CSCPSGWMGTVC----GQPCPEGRFGKNCSQE 280
Query: 114 -PCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDAC----------LSHPCANGSTCTTV 162
C NGGTC T +C C G+TG+ CQ D C + C NG C V
Sbjct: 281 CQCHNGGTC---DAATGQCHCSPGYTGERCQ--DECPVGTYGVLCAETCQCVNGGKCYHV 335
Query: 163 ANQFSCKCLTGFTGQKCETDV-------NECD--IPGHCQHGGTCLNLPGSYQCQCPQGF 213
+ +C C GF G++CE + +CD P H ++ +C P S +C C G+
Sbjct: 336 SG--ACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSC--HPMSGECACKPGW 391
Query: 214 TGQYCDSLYVPCAPS----------PCVNGGTCRQTGDFTFECNCLPGFEGSTCER---- 259
+G YC+ C+P C NG C T +C C PGF+G C
Sbjct: 392 SGLYCNE---TCSPGFYGEACQQICSCQNGADC---DSVTGKCTCAPGFKGIDCSTPCPL 445
Query: 260 ---NIDDCPNHRCQNGGVC--VDGVNTYNCRCPPQWTGQFCTEDVDE------CLLQPNA 308
I+ C+N VC VDG +C C W G C+ C L
Sbjct: 446 GTYGINCSSRCGCKNDAVCSPVDG----SCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQ- 500
Query: 309 CQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAF-------ASCTPGSTCIDRVASFS 361
C NGG C +G C C GW G+ C D + C+ C +
Sbjct: 501 CLNGGACNTLDG--TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGC--HPTTGH 556
Query: 362 CMCPEGKAGLLCHLDDAC--------ISNPCH--KGALCDTNPLNGQYICTCPQGYKGAD 411
C C G +G+ H D C S PC+ GA C +P +G IC C G++G
Sbjct: 557 CRCLPGWSGV--HCDSVCAEGRWGPNCSLPCYCKNGASC--SPDDG--ICECAPGFRGTT 610
Query: 412 CTEDVDECAMANSNPCEHAGKCVNTDGAFH-----CECLKGYAGPRC-------EMDINE 459
C + + + +CV++ G H C+CL G+ G C N
Sbjct: 611 C-QRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNC 669
Query: 460 CHSDPCQNDATC--LDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQ 517
C N+ TC +D+ +C C PG+ G C S P
Sbjct: 670 AGICTCTNNGTCNPIDR----SCQCYPGWIGSDC--------SQP--------------- 702
Query: 518 CLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEEN--IDNCD 575
CPP GP C I C+ C NGA C + EC+C G+TG+ C + +
Sbjct: 703 --CPPAHWGPNC---IHTCN---CHNGAFCSAYDG--ECKCTPGWTGLYCTQRCPLGFYG 752
Query: 576 PDPCHHGQCQDGID----SYTCICNPGYMGAICSDQIDE------CYS-SPCLNDGRCID 624
D QCQ+G D S C C G+MG C + C CLN+ C D
Sbjct: 753 KDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTC-D 811
Query: 625 LVNGYQCNCQPGTSGVNCE 643
+ G C C PG G C+
Sbjct: 812 HITG-TCYCSPGWKGARCD 829
Score = 147 bits (370), Expect = 2e-34
Identities = 123/427 (28%), Positives = 173/427 (40%), Gaps = 81/427 (18%)
Query: 48 TGYCKCPEGFLGEYCQHRDPCEKN----RCQNGGTCVAQAMLGKA--TCRCASGFTGEDC 101
TG C C GF G C PC C + C A+ +C C +G+ G DC
Sbjct: 425 TGKCTCAPGFKGIDCS--TPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC 482
Query: 102 QY-----STSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT--DACLSHPCA 154
+ C ++ CLNGG C+ L CTC G+ G++C+ D CA
Sbjct: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLDGT---CTCAPGWRGEKCELPCQDGTYGLNCA 539
Query: 155 NGSTCTTV----ANQFSCKCLTGFTGQKCETDVNE------CDIPGHCQHGGTCLNLPGS 204
C+ C+CL G++G C++ E C +P +C++G +C P
Sbjct: 540 ERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCS--PDD 597
Query: 205 YQCQCPQGFTGQYCDSLYVP------CAPS--PCVNG-GTCRQTGDFTFECNCLPGFEGS 255
C+C GF G C + P C+ + CV+ G C T C+CLPGF G+
Sbjct: 598 GICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHH---ITGLCDCLPGFTGA 654
Query: 256 TCERNIDDCPNHR----------CQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQ 305
C + CP+ R C N G C +C+C P W G C++
Sbjct: 655 LCN---EVCPSGRFGKNCAGICTCTNNGTC--NPIDRSCQCYPGWIGSDCSQPCPPAHWG 709
Query: 306 PNA-----CQNGGTCANRNGGYGCVCVNGWSGDDCSENID------DCAF-ASCTPGSTC 353
PN C NG C+ +G C C GW+G C++ DCA C G+ C
Sbjct: 710 PNCIHTCNCHNGAFCSAYDGE--CKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC 767
Query: 354 IDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA--LCDT-NPLNGQYI---CTCPQGY 407
D ++ C C G G H + C S G +CD N +I C C G+
Sbjct: 768 -DHISG-QCTCRTGFMGR--HCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGW 823
Query: 408 KGADCTE 414
KGA C +
Sbjct: 824 KGARCDQ 830
Score = 128 bits (321), Expect = 8e-29
Identities = 125/459 (27%), Positives = 164/459 (35%), Gaps = 122/459 (26%)
Query: 1137 CPLGY-TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVD------ 1189
CP Y +G C + CA C HG I C+C PG+ G NC D
Sbjct: 95 CPGFYESGEMC---VPHCADK-CVHGRC----IAPNTCQCEPGWGGTNCSSACDGDHWGP 146
Query: 1190 ECQNQ-PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENID------DCARGPHCLNGGQCM 1242
C ++ C+NG C + C C G RG CE+ + DC + C NG C
Sbjct: 147 HCTSRCQCKNGALCNPITG--ACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC- 203
Query: 1243 DRIGGYSCRCLPGFAGERCE-----GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT 1297
D + G CRC PG+ G CE G C + C +T + C C S +
Sbjct: 204 DHVTG-ECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGE--CSCPSGWM 260
Query: 1298 GRHCET------FVDVCPQ-MPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCG--- 1347
G C F C Q C NGGTC A+ C C PG++G RCQ C
Sbjct: 261 GTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQ-----CHCSPGYTGERCQDECPVGT 315
Query: 1348 -------QVKCRKGEQCVHTA---------SGPRC---FCPSPR---DCESGCASSPC-- 1383
+C G +C H + +G RC CP C+ C PC
Sbjct: 316 YGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRC---PCHL 372
Query: 1384 QHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEAC 1443
++ SCHP C C P +SG C ++ C+ C + C
Sbjct: 373 ENTHSCHPMSG----ECACKPGWSGLYC---------------NETCSPGFYGEACQQIC 413
Query: 1444 ---NSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNS 1500
N C G C+ +CS+P P Y N C C
Sbjct: 414 SCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGIN-CSSRCG--------------- 457
Query: 1501 KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQP 1539
CK D C+ D C + GW G+DC+ P
Sbjct: 458 --CKNDAVCSP------VDGSCTCK-AGWHGVDCSIRCP 487
Score = 94.4 bits (233), Expect = 1e-18
Identities = 82/324 (25%), Positives = 119/324 (36%), Gaps = 101/324 (31%)
Query: 17 LCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNR---- 72
L C + L C + + C + C H TG+C+C G+ G +C C + R
Sbjct: 527 LPCQDGTYGLNCAERCD-CSHADGC---HPTTGHCRCLPGWSGVHCD--SVCAEGRWGPN 580
Query: 73 ------CQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-----HPCFVSRP------- 114
C+NG +C C CA GF G CQ S H C + P
Sbjct: 581 CSLPCYCKNGASCSPD----DGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSG 636
Query: 115 --------------------------------------CLNGGTCHMLSRDTYECTCQVG 136
C N GTC+ + R C C G
Sbjct: 637 PCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRS---CQCYPG 693
Query: 137 FTGKECQ-------WTDACL-SHPCANGSTCTTVANQFSCKCLTGFTG----QKCETDV- 183
+ G +C W C+ + C NG+ C+ + CKC G+TG Q+C
Sbjct: 694 WIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE--CKCTPGWTGLYCTQRCPLGFY 751
Query: 184 -NECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSL-------YVPCAPSPCVNGGT 235
+C + CQ+G C ++ G QC C GF G++C+ Y C+N T
Sbjct: 752 GKDCALICQCQNGADCDHISG--QCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNST 809
Query: 236 CRQTGDFTFECNCLPGFEGSTCER 259
C T C C PG++G+ C++
Sbjct: 810 CDH---ITGTCYCSPGWKGARCDQ 830
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 277 bits (709), Expect = 8e-74
Identities = 269/941 (28%), Positives = 347/941 (36%), Gaps = 287/941 (30%)
Query: 403 CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHS 462
CP Y+ D C + C H G+CV+ D C C G+ GP C + H
Sbjct: 89 CPGYYESGDF------CIPLCTEECVH-GRCVSPDT---CHCEPGWGGPDCSSGCDSDHW 138
Query: 463 DP-------CQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNR 515
P CQN A C G C+C GF+G CE
Sbjct: 139 GPHCSNRCQCQNGALCNPITGA--CVCAAGFRGWRCEE---------------------- 174
Query: 516 FQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCD 575
LC PG G CQ+ C +GA C P EC CA G+TGV CEE C
Sbjct: 175 ---LCAPGTHGKGCQLPCQ------CRHGASC--DPRAGECLCAPGYTGVYCEE---LCP 220
Query: 576 PD----------PCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDL 625
P PC +G I C C PG+ GA+C+
Sbjct: 221 PGSHGAHCELRCPCQNGGTCHHITG-ECACPPGWTGAVCAQP------------------ 261
Query: 626 VNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDID- 684
C PGT G NC DC PC HG D + C C+ G+ G RC +
Sbjct: 262 -------CPPGTFGQNCS---QDC---PCHHGGQCDHVTG-QCHCTAGYMGDRCQEECPF 307
Query: 685 -----ECASN-PCRKGATCI---------NGVNGFRC---ICPEGPHHPSCY----SQVN 722
+C+ + C G C G G RC +CPEG H P C +
Sbjct: 308 GSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDAD 367
Query: 723 ECLSNPCIHGNCT--GGLSGYKC--LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNG 778
+S + G CT G SG+ C C G+ G C+ L CQNG C ++ G
Sbjct: 368 NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQ------LPCTCQNGADCHSITGG 421
Query: 779 YRCTCKKGFKGYNCQVNIDECASNP-------CLNQGTCFDDISGYTCHCVLPYTGKNCQ 831
CTC GF G C V+ P C N GTC + G +C C + G +C
Sbjct: 422 --CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTC-SPVDG-SCTCKEGWQGLDC- 476
Query: 832 TVLAP-------CSPN-PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCM 883
T+ P C+ + C N A C +C C PGW G C +
Sbjct: 477 TLPCPSGTWGLNCNESCTCANGAACSPIDG----SCSCTPGWLGDTCEL----------- 521
Query: 884 NHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTG 943
CP G G++C E D C + C D V T C CL G+TG
Sbjct: 522 --------------PCPDGTFGLNCSEHCD------CSHADGC-DPV-TGHCCCLAGWTG 559
Query: 944 DKCQTDM-------NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSC 996
+C + N +S C+NGG+CS S C+C GF G C+
Sbjct: 560 IRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGS--CECAPGFRGPLCQR---------- 607
Query: 997 FNGGTCVDGINSFSCLCPVGFTGSFCLHEINEC--SSHPCLNEG---TCVDGLGTYRCS- 1050
+CP GF G C C SS PC + C+ G C+
Sbjct: 608 ---------------ICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQ 652
Query: 1051 -CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAA 1109
C GY G++C LCS C N GTC + C C GW G C S
Sbjct: 653 VCAGGYFGQDC---AQLCS---CANNGTC--SPIDGSCQCFPGWIGKDC-----SQACPP 699
Query: 1110 SRRGVLVEHLCQ-HSGVCINAGNTHYCQCPLGYTGSYCEEQL------DECAS-NPCQHG 1161
G H C H+G +A C C G+TG +C ++ +C CQ+G
Sbjct: 700 GFWGPACFHACSCHNGASCSA-EDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNG 758
Query: 1162 ATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLL 1221
A+C D I G +C C G+ G +CE C PGT G
Sbjct: 759 ASC-DHISG-KCTCRTGFTGQHCEQR-------------------------CAPGTFGYG 791
Query: 1222 CEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE 1262
C++ + C+N C D + G +C C PGF G RC+
Sbjct: 792 CQQLCE-------CMNNSTC-DHVTG-TCYCSPGFKGIRCD 823
Score = 270 bits (689), Expect = 2e-71
Identities = 268/929 (28%), Positives = 338/929 (36%), Gaps = 252/929 (27%)
Query: 524 FTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYEC--------------QCATGFTGVLCEE 569
+ P QI C T LN KC H Y+ QC G+ E
Sbjct: 42 YAHPFDQIYYTRC--TDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYY-----E 94
Query: 570 NIDNCDP---DPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP-CLNDGRCIDL 625
+ D C P + C HG+C + TC C PG+ G CS D + P C N +C
Sbjct: 95 SGDFCIPLCTEECVHGRC---VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQC--- 148
Query: 626 VNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDE 685
NG CN G +CVC+ GF G RC
Sbjct: 149 QNGALCNPITG------------------------------ACVCAAGFRGWRCE----- 173
Query: 686 CASNPCRKGATCINGVNGFRCICP-EGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC- 743
C G +G C P + H SC + ECL C G +G C
Sbjct: 174 ---------ELCAPGTHGKGCQLPCQCRHGASCDPRAGECL--------CAPGYTGVYCE 216
Query: 744 -LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNI------ 796
LC G G +CE L PCQNGGTC ++ C C G+ G C
Sbjct: 217 ELCPPGSHGAHCE------LRCPCQNGGTCHHITG--ECACPPGWTGAVCAQPCPPGTFG 268
Query: 797 DECASN-PCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA------PCSPN-PCENAAVC 848
C+ + PC + G C D ++G CHC Y G CQ CS + C N C
Sbjct: 269 QNCSQDCPCHHGGQC-DHVTGQ-CHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQC 326
Query: 849 KESPNFESYTCLCAPGWQGQRCTIDI------DECISKPCM----NHGLCHNTQGSYMCE 898
+ C C PG++G RC + + PC N CH G+ C
Sbjct: 327 SPTTG----ACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA--CT 380
Query: 899 CPPGFSGMDCEEDI------DDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMN 951
C PG+SG C E D C L CQNG C T C C PGF G+ C
Sbjct: 381 CQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHS--ITGGCTCAPGFMGEVCAVSCA 438
Query: 952 ECLSEP-------CKNGGTCSDYVNSYTCK-----------CQAGFDGVHCENNINECTE 993
P C NGGTCS S TCK C +G G++C + CT
Sbjct: 439 AGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNES---CT- 494
Query: 994 SSCFNGGTC--VDGINSFSCLCPVGFTGSFCLHEINE------CSSH-PCLNEGTCVDGL 1044
C NG C +DG SC C G+ G C + CS H C + C
Sbjct: 495 --CANGAACSPIDG----SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVT 548
Query: 1045 GTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVS 1104
G C C G+TG C S P G C C +G + C + S
Sbjct: 549 G--HCCCLAGWTGIRCD------STCPPGRWGP----NCSVSCSCENGGS---CSPEDGS 593
Query: 1105 CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDEC--ASNPCQHGA 1162
C+ A RG L + +C P G+ G C + C +S PC H
Sbjct: 594 CECAPGFRGPLCQRIC-----------------PPGFYGHGCAQPCPLCVHSSRPCHH-- 634
Query: 1163 TCSDFIGGYRCECVPGYQGVNCE-------YEVDECQNQPCQNGGTCIDLVNHFKCSCPP 1215
I G CEC+PG+ G C + D Q C N GTC + C C P
Sbjct: 635 -----ISGI-CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDG--SCQCFP 686
Query: 1216 GTRGLLCEENIDDCARGPHCL------NGGQCMDRIGGYSCRCLPGFAG----ERCEGDI 1265
G G C + GP C NG C G +C C PG+ G +RC
Sbjct: 687 GWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDG--ACHCTPGWTGLFCTQRCPAAF 744
Query: 1266 --NECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE------TFVDVCPQM-PCLNG 1316
+C C + C ++ C CR+ FTG+HCE TF C Q+ C+N
Sbjct: 745 FGKDC-GRVCQCQNGASCDHISGK--CTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNN 801
Query: 1317 GTCAVASNMPDGFICRCPPGFSGARCQSS 1345
TC + C C PGF G RC +
Sbjct: 802 STCDHVTGT-----CYCSPGFKGIRCDQA 825
Score = 249 bits (637), Expect = 2e-65
Identities = 236/818 (28%), Positives = 309/818 (37%), Gaps = 239/818 (29%)
Query: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-------HRDPCE-KNRCQNGGTCVAQAMLG 86
C N +C TG C C GF G C+ H C+ +C++G +C +A
Sbjct: 148 CQNGALCNPI---TGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRA--- 201
Query: 87 KATCRCASGFTGEDCQY-----STSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE 141
C CA G+TG C+ S C + PC NGGTCH + T EC C G+TG
Sbjct: 202 -GECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHI---TGECACPPGWTGAV 257
Query: 142 CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL 201
C + PC G+ GQ C D C HGG C ++
Sbjct: 258 C-------AQPCPPGT-----------------FGQNCSQDC-------PCHHGGQCDHV 286
Query: 202 PGSYQCQCPQGFTGQYCD------SLYVPCAP-SPCVNGGTCRQTGDFTFECNCLPGFEG 254
G QC C G+ G C S C+ C NGG C T T C C PG++G
Sbjct: 287 TG--QCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT---TGACECEPGYKG 341
Query: 255 STCERNIDDCPNHRCQNGGVCV-----DGVNTYNCR-------CPPQWTGQFCTEDV--- 299
C+ + CP +G C D NT +C C P W+G C E
Sbjct: 342 PRCQERL--CPEG--LHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVG 397
Query: 300 ---DECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENI------DDC-AFASCTP 349
D C L P CQNG C + G GC C G+ G+ C+ + +C + SC
Sbjct: 398 YYGDGCQL-PCTCQNGADCHSITG--GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNN 454
Query: 350 GSTCIDRVASFSCMCPEGKAGLLCHL-----------DDACISNPCHKGALCDTNPLNGQ 398
G TC SC C EG GL C L +++C C GA C +P++G
Sbjct: 455 GGTC--SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC---TCANGAAC--SPIDGS 507
Query: 399 YICT-----------CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKG 447
CT CP G G +C+E D C HA C G HC CL G
Sbjct: 508 CSCTPGWLGDTCELPCPDGTFGLNCSEHCD---------CSHADGCDPVTG--HCCCLAG 556
Query: 448 YAGPRCEMDI-------NECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQS 500
+ G RC+ N S C+N +C + G +C C PGF+G C
Sbjct: 557 WTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDG--SCECAPGFRGPLC--------- 605
Query: 501 NPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC--SSTPCLNGAKCIDHPNGYECQC 558
Q +CPPGF G C C SS PC H +G C+C
Sbjct: 606 ----------------QRICPPGFYGHGCAQPCPLCVHSSRPC-------HHISGI-CEC 641
Query: 559 ATGFTGVLCEE-------NIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQI--- 608
GF+G LC + D C + ID +C C PG++G CS
Sbjct: 642 LPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDG-SCQCFPGWIGKDCSQACPPG 700
Query: 609 ---DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF------DDCAS-NPCIHGI 658
C+ + ++G +G C+C PG +G+ C DC C +G
Sbjct: 701 FWGPACFHACSCHNGASCSAEDG-ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGA 759
Query: 659 CMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCY 718
D I+ C C GFTGQ C C G G+ C
Sbjct: 760 SCDHISG-KCTCRTGFTGQHCE--------------QRCAPGTFGYGC------------ 792
Query: 719 SQVNECLSN-PCIHGNCTGGLSGYKCLCDAGWVGINCE 755
Q+ EC++N C H T C C G+ GI C+
Sbjct: 793 QQLCECMNNSTCDHVTGT-------CYCSPGFKGIRCD 823
Score = 243 bits (620), Expect = 2e-63
Identities = 233/853 (27%), Positives = 307/853 (35%), Gaps = 276/853 (32%)
Query: 79 CVAQAMLGKATCRCASGFTGEDCQYSTSHP-----CFVSRPCLNGGTCHMLSRDTYECTC 133
CV + TC C G+ G DC C C NG C+ + T C C
Sbjct: 107 CVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPI---TGACVC 163
Query: 134 QVGFTGKECQWTDACLSH--------PCANGSTCTTVANQFSCKCLTGFTGQKCE----- 180
GF G C+ A +H C +G++C A + C C G+TG CE
Sbjct: 164 AAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGE--CLCAPGYTGVYCEELCPP 221
Query: 181 -TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPS----------P 229
+ C++ CQ+GGTC ++ G +C CP G+TG C PC P P
Sbjct: 222 GSHGAHCELRCPCQNGGTCHHITG--ECACPPGWTGAVCAQ---PCPPGTFGQNCSQDCP 276
Query: 230 CVNGGTCRQTGDFTFECNCLPGFEGSTCERNID------DCPNH-RCQNGGVC------- 275
C +GG C T +C+C G+ G C+ C H C NGG C
Sbjct: 277 CHHGGQCDHV---TGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGAC 333
Query: 276 ------------------------------VDGVNTYNCR-------CPPQWTGQFCTED 298
D NT +C C P W+G C E
Sbjct: 334 ECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNES 393
Query: 299 V------DECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENI------DDC-AFA 345
D C L P CQNG C + G GC C G+ G+ C+ + +C +
Sbjct: 394 CPVGYYGDGCQL-PCTCQNGADCHSITG--GCTCAPGFMGEVCAVSCAAGTYGPNCSSIC 450
Query: 346 SCTPGSTCIDRVASFSCMCPEGKAGLLCHL-----------DDACISNPCHKGALCDTNP 394
SC G TC SC C EG GL C L +++C C GA C +P
Sbjct: 451 SCNNGGTC--SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC---TCANGAAC--SP 503
Query: 395 LNGQYICT-----------CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE 443
++G CT CP G G +C+E D C HA C G HC
Sbjct: 504 IDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCD---------CSHADGCDPVTG--HCC 552
Query: 444 CLKGYAGPRCEMDI-------NECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEIN 496
CL G+ G RC+ N S C+N +C + G +C C PGF+G C
Sbjct: 553 CLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDG--SCECAPGFRGPLC----- 605
Query: 497 ECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC--SSTPCLNGAKCIDHPNGY 554
Q +CPPGF G C C SS PC H +G
Sbjct: 606 --------------------QRICPPGFYGHGCAQPCPLCVHSSRPC-------HHISGI 638
Query: 555 ECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSS 614
C+C GF+G LC + +C GY G C+
Sbjct: 639 -CECLPGFSGALCNQ------------------------VCAGGYFGQDCAQLCS----- 668
Query: 615 PCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP-CIHGI-CMDGIN----RYSC 668
C N+G C + C C PG G +C P C H C +G + +C
Sbjct: 669 -CANNGTCSPIDG--SCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGAC 725
Query: 669 VCSPGFTG----QRCNIDI--DECAS-NPCRKGATCINGVNGFRCICPEGPHHPSCYSQV 721
C+PG+TG QRC +C C+ GA+C + ++G +C C G C +
Sbjct: 726 HCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASC-DHISG-KCTCRTGFTGQHCEQR- 782
Query: 722 NECLSNPCIHGNCTGGLSGYKC--LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGY 779
C G GY C LC+ C N TCD++
Sbjct: 783 ------------CAPGTFGYGCQQLCE-------------------CMNNSTCDHVTG-- 809
Query: 780 RCTCKKGFKGYNC 792
C C GFKG C
Sbjct: 810 TCYCSPGFKGIRC 822
Score = 224 bits (572), Expect = 6e-58
Identities = 214/766 (27%), Positives = 275/766 (35%), Gaps = 213/766 (27%)
Query: 16 WLC---CAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-------HR 65
W C CA H C+ + C + C G C C G+ G YC+ H
Sbjct: 170 WRCEELCAPGTHGKGCQLPCQ-CRHGASC---DPRAGECLCAPGYTGVYCEELCPPGSHG 225
Query: 66 DPCE-KNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQY-----STSHPCFVSRPCLNGG 119
CE + CQNGGTC + G+ C C G+TG C + C PC +GG
Sbjct: 226 AHCELRCPCQNGGTC--HHITGE--CACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGG 281
Query: 120 TCHMLSRDTYECTCQVGFTGKECQ-------WTDACLSH-PCANGSTCTTVANQFSCKCL 171
C + T +C C G+ G CQ + C H C NG C+ +C+C
Sbjct: 282 QCDHV---TGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTG--ACECE 336
Query: 172 TGFTGQKCETDV-------NECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYC------ 218
G+ G +C+ + C +P C T P + C C G++G +C
Sbjct: 337 PGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPV 396
Query: 219 ----DSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNI------DDCPN-H 267
D +PC C NG C T C C PGF G C + +C +
Sbjct: 397 GYYGDGCQLPCT---CQNGADCH---SITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSIC 450
Query: 268 RCQNGGVC--VDGVNTYNCRCPPQWTGQFCTEDVDECLLQPN-----ACQNGGTCANRNG 320
C NGG C VDG +C C W G CT N C NG C+ +G
Sbjct: 451 SCNNGGTCSPVDG----SCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDG 506
Query: 321 GYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLC--HLDDA 378
C C GW GD C CP+G GL C H D
Sbjct: 507 --SCSCTPGWLGDTC-------------------------ELPCPDGTFGLNCSEHCD-- 537
Query: 379 CISNPCHKGALCDTNPLNGQYIC-----------TCPQGYKGADCTEDVDECAMANSNPC 427
C CD P+ G C TCP G G +C+ S C
Sbjct: 538 -----CSHADGCD--PVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV---------SCSC 581
Query: 428 EHAGKCVNTDGAFHCECLKGYAGPRCEMDI------NECHSDPCQ---NDATCLDKIGGF 478
E+ G C DG+ CEC G+ GP C+ + C + PC + + I G
Sbjct: 582 ENGGSCSPEDGS--CECAPGFRGPLCQRICPPGFYGHGC-AQPCPLCVHSSRPCHHISGI 638
Query: 479 TCLCMPGFKGVHCELEI------NEC-QSNPCVNNGQCVDKVNRFQCL-----------C 520
C C+PGF G C +C Q C NNG C QC C
Sbjct: 639 -CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQAC 697
Query: 521 PPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNC--DPDP 578
PPGF GP C CS C NGA C C C G+TG+ C + D
Sbjct: 698 PPGFWGPAC---FHACS---CHNGASCSAEDGA--CHCTPGWTGLFCTQRCPAAFFGKDC 749
Query: 579 CHHGQCQDGID----SYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQ 634
QCQ+G S C C G+ G C + C
Sbjct: 750 GRVCQCQNGASCDHISGKCTCRTGFTGQHCEQR-------------------------CA 784
Query: 635 PGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCN 680
PGT G C+ + ++ C H + G +C CSPGF G RC+
Sbjct: 785 PGTFGYGCQQLCECMNNSTCDH---VTG----TCYCSPGFKGIRCD 823
Score = 221 bits (564), Expect = 5e-57
Identities = 218/759 (28%), Positives = 276/759 (36%), Gaps = 147/759 (19%)
Query: 858 TCLCAPGWQGQRCTIDIDE------CISK-PCMNHGLCHNTQGSYMCECPPGFSGMDCEE 910
TC C PGW G C+ D C ++ C N LC+ G+ C C GF G CEE
Sbjct: 117 TCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGA--CVCAAGFRGWRCEE 174
Query: 911 DI------DDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQ------TDMNEC-LSE 956
C L C++G SC CLC PG+TG C+ + C L
Sbjct: 175 LCAPGTHGKGCQLPCQCRHGASCDPRAG--ECLCAPGYTGVYCEELCPPGSHGAHCELRC 232
Query: 957 PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-------NECTESSCFNGGTCVDGINSF 1009
PC+NGGTC C C G+ G C N + C +GG C D +
Sbjct: 233 PCQNGGTCHHITGE--CACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQC-DHVTG- 288
Query: 1010 SCLCPVGFTGSFCLHEIN------ECSSH-PCLNEGTCVDGLGTYRCSCPLGYTGKNCQT 1062
C C G+ G C E +CS H C N G C G C C GY G CQ
Sbjct: 289 QCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA--CECEPGYKGPRCQE 346
Query: 1063 LVNLCSRS----------PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRR 1112
LC PC T C C GW+G +C N SC +
Sbjct: 347 --RLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHC---NESCPVGYYGD 401
Query: 1113 GVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNP-------CQHGATCS 1165
G + CQ+ C + T C C G+ G C P C +G TCS
Sbjct: 402 GCQLPCTCQNGADCHSI--TGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCS 459
Query: 1166 DFIGGYRCECVPGYQGVNCE-------YEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR 1218
G C C G+QG++C + ++ ++ C NG C + CSC PG
Sbjct: 460 PVDGS--CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDG--SCSCTPGWL 515
Query: 1219 GLLCEENIDDCARGPHCLNGGQCM-----DRIGGYSCRCLPGFAGERCE-----GDINEC 1268
G CE D G +C C D + G+ C CL G+ G RC+ G
Sbjct: 516 GDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCC-CLAGWTGIRCDSTCPPGRWGPN 574
Query: 1269 LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA------VA 1322
S CS E C D C C F G C+ +CP P G CA V
Sbjct: 575 CSVSCSCENGGSCSP--EDGSCECAPGFRGPLCQR---ICP--PGFYGHGCAQPCPLCVH 627
Query: 1323 SNMPDGFI---CRCPPGFSGARCQSSC-----GQ-----VKCRKGEQCVHTASGPRCFCP 1369
S+ P I C C PGFSGA C C GQ C C +CF P
Sbjct: 628 SSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCF-P 686
Query: 1370 S--PRDCESGCA----SSPCQHGGSCH--PQRQPPYYSCQCAPPFSGSRCELYTAPPSTP 1421
+DC C C H SCH +C C P ++G C
Sbjct: 687 GWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFC------TQRC 740
Query: 1422 PATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCD 1481
PA + C VC + N +C G C+ +C + C
Sbjct: 741 PAAFFGKDCG-----RVC-QCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTF-GYGCQ 793
Query: 1482 ELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQ 1520
+LC EC+ +N C + TC YC+ FK CDQ
Sbjct: 794 QLC---ECM-NNSTCDHVTGTC----YCSPGFKGIRCDQ 824
Score = 129 bits (323), Expect = 5e-29
Identities = 114/420 (27%), Positives = 147/420 (35%), Gaps = 75/420 (17%)
Query: 1172 RCECVPGY--QGVNC-EYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDD 1228
R +C PGY G C +EC + C + TC C PG G C D
Sbjct: 85 RSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTC---------HCEPGWGGPDCSSGCDS 135
Query: 1229 CARGPHCLNGGQCM-----DRIGGYSCRCLPGFAGERCE-----GDINECLSNPCSSEGS 1278
GPHC N QC + I G +C C GF G RCE G + PC
Sbjct: 136 DHWGPHCSNRCQCQNGALCNPITG-ACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHG 194
Query: 1279 LDCIQLTNDYLCVCRSAFTGRHCETFVDVCP----------QMPCLNGGTCAVASNMPDG 1328
C + C+C +TG +CE ++CP + PC NGGTC +
Sbjct: 195 ASCDPRAGE--CLCAPGYTGVYCE---ELCPPGSHGAHCELRCPCQNGGTCHHITGE--- 246
Query: 1329 FICRCPPGFSGARCQSSC-----GQ-----VKCRKGEQCVHTASGPRCFCPS-------P 1371
C CPPG++GA C C GQ C G QC H +C C +
Sbjct: 247 --CACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTG--QCHCTAGYMGDRCQ 302
Query: 1372 RDCESGCASSPCQHGGSCH--PQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQY 1429
+C G C CH Q P +C+C P + G RC+ P C
Sbjct: 303 EECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPC 362
Query: 1430 CADKARDGVCDEACNSHACQ--WDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTV 1487
D C + CQ W G C+ + + LPC C +
Sbjct: 363 PCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGC 422
Query: 1488 ECL--FDNFECQGNSKTCKYDKYCADHFKDNH------CDQGCNSEECGWDGLDCAADQP 1539
C F C + Y C+ N+ D C +E GW GLDC P
Sbjct: 423 TCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKE-GWQGLDCTLPCP 481
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 271 bits (692), Expect = 8e-72
Identities = 141/363 (38%), Positives = 184/363 (50%), Gaps = 19/363 (5%)
Query: 704 FRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLS 763
+R +C E + C C G+ T G G K +C+ GW G C + CL
Sbjct: 175 YRFVCDEHYYGEGCSVF---CRPRDDAFGHFTCGERGEK-VCNPGWKGPYCT--EPICLP 228
Query: 764 NPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVL 823
+ G CD C C+ G++G C DEC P GTC + C+C
Sbjct: 229 GCDEQHGFCDK---PGECKCRVGWQGRYC----DECIRYPGCLHGTCQQP---WQCNCQE 278
Query: 824 PYTGKNCQTVLAPCSPN-PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPC 882
+ G C L C+ + PC+N A C + SYTC C PG+ G C + IDEC PC
Sbjct: 279 GWGGLFCNQDLNYCTHHKPCKNGATCTNTGQ-GSYTCSCRPGYTGATCELGIDECDPSPC 337
Query: 883 MNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNT-FSCLCLPGF 941
N G C + + SY C CPPGF G CE C PC NGG C D + +SC C G+
Sbjct: 338 KNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY 397
Query: 942 TGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGT 1001
+G C+ ++ C S PC NG C D ++Y C+CQAGF G HC++N+++C S C NGGT
Sbjct: 398 SGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGT 457
Query: 1002 CVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQ 1061
C DG+N FSC CP G+TG C ++ C PC N TC + Y C C GY G NCQ
Sbjct: 458 CRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQ 517
Query: 1062 TLV 1064
L+
Sbjct: 518 FLL 520
Score = 243 bits (619), Expect = 2e-63
Identities = 124/344 (36%), Positives = 174/344 (50%), Gaps = 32/344 (9%)
Query: 928 DGVNTFSC------LCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDG 981
D F+C +C PG+ G C + CL + G C CKC+ G+ G
Sbjct: 197 DAFGHFTCGERGEKVCNPGWKGPYCTEPI--CLPGCDEQHGFCD---KPGECKCRVGWQG 251
Query: 982 VHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH-PCLNEGTC 1040
+C+ EC GTC + C C G+ G FC ++N C+ H PC N TC
Sbjct: 252 RYCD----ECIRYPGCLHGTCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATC 304
Query: 1041 VD-GLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCD 1099
+ G G+Y CSC GYTG C+ ++ C SPCKN G+C + C CP G+ G C+
Sbjct: 305 TNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICE 364
Query: 1100 VPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY-CQCPLGYTGSYCEEQLDECASNPC 1158
+ ++C + C + G C ++ + Y C+CP+GY+G CE+++D C+S+PC
Sbjct: 365 LSAMTC----------ADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPC 414
Query: 1159 QHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR 1218
+GA C D Y C C G+ G +C+ VD+C + PC NGGTC D VN F C+CPPG
Sbjct: 415 SNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYT 474
Query: 1219 GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE 1262
G C + C P C NG C +R Y C C G+ G C+
Sbjct: 475 GRNCSAPVSRCEHAP-CHNGATCHERGHRYVCECARGYGGPNCQ 517
Score = 240 bits (612), Expect = 1e-62
Identities = 134/390 (34%), Positives = 182/390 (46%), Gaps = 31/390 (7%)
Query: 194 HGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGG-TCRQTGDFTFECNCLPGF 252
H +L SY+ C + + G+ C V C P G TC + G+ C PG+
Sbjct: 164 HSSGRTDLKYSYRFVCDEHYYGEGCS---VFCRPRDDAFGHFTCGERGEKV----CNPGW 216
Query: 253 EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNG 312
+G C I C + G C C+C W G++C DEC+ P
Sbjct: 217 KGPYCTEPI--CLPGCDEQHGFCD---KPGECKCRVGWQGRYC----DECIRYPGCLH-- 265
Query: 313 GTCANRNGGYGCVCVNGWSGDDCSENIDDCAFAS-CTPGSTCIDR-VASFSCMCPEGKAG 370
GTC + C C GW G C+++++ C C G+TC + S++C C G G
Sbjct: 266 GTCQQP---WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG 322
Query: 371 LLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEH 429
C L D C +PC G C L Y CTCP G+ G C CA PC +
Sbjct: 323 ATCELGIDECDPSPCKNGGSC--TDLENSYSCTCPPGFYGKICELSAMTCA---DGPCFN 377
Query: 430 AGKCVNT-DGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKG 488
G+C ++ DG + C C GY+G CE I+ C S PC N A C+D + C C GF G
Sbjct: 378 GGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSG 437
Query: 489 VHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCI 548
HC+ +++C S+PC N G C D VN F C CPPG+TG C + C PC NGA C
Sbjct: 438 RHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCH 497
Query: 549 DHPNGYECQCATGFTGVLCEENIDNCDPDP 578
+ + Y C+CA G+ G C+ + P P
Sbjct: 498 ERGHRYVCECARGYGGPNCQFLLPELPPGP 527
Score = 238 bits (608), Expect = 4e-62
Identities = 129/376 (34%), Positives = 186/376 (49%), Gaps = 27/376 (7%)
Query: 666 YSCVCSPGFTGQRCNIDIDECASNPCRKGA-TCINGVNGFRCICPEGPHHPSCYSQVNEC 724
Y VC + G+ C++ C G TC G G + +C G P C + C
Sbjct: 175 YRFVCDEHYYGEGCSVF---CRPRDDAFGHFTC--GERGEK-VCNPGWKGPYCTEPI--C 226
Query: 725 LSNPCI--HGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCT 782
L C HG C +C C GW G C+ EC+ P GTC ++C
Sbjct: 227 LPG-CDEQHGFCD---KPGECKCRVGWQGRYCD----ECIRYPGCLHGTCQQ---PWQCN 275
Query: 783 CKKGFKGYNCQVNIDECASN-PCLNQGTCFDDISG-YTCHCVLPYTGKNCQTVLAPCSPN 840
C++G+ G C +++ C + PC N TC + G YTC C YTG C+ + C P+
Sbjct: 276 CQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPS 335
Query: 841 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNT-QGSYMCEC 899
PC+N C + N SY+C C PG+ G+ C + C PC N G C ++ G Y C C
Sbjct: 336 PCKNGGSCTDLEN--SYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRC 393
Query: 900 PPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCK 959
P G+SG +CE+ ID C ++PC NG C+D + + C C GF+G C ++++C S PC
Sbjct: 394 PVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCA 453
Query: 960 NGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTG 1019
NGGTC D VN ++C C G+ G +C ++ C + C NG TC + + + C C G+ G
Sbjct: 454 NGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGG 513
Query: 1020 SFCLHEINECSSHPCL 1035
C + E P +
Sbjct: 514 PNCQFLLPELPPGPAV 529
Score = 236 bits (603), Expect = 2e-61
Identities = 124/338 (36%), Positives = 167/338 (49%), Gaps = 22/338 (6%)
Query: 286 CPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFA 345
C P W G +CTE + CL P + G C C C GW G C E I +
Sbjct: 212 CNPGWKGPYCTEPI--CL--PGCDEQHGFCDKPGE---CKCRVGWQGRYCDECI---RYP 261
Query: 346 SCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DACISN-PCHKGALCDTNPLNGQYICTC 403
C G TC + C C EG GL C+ D + C + PC GA C TN G Y C+C
Sbjct: 262 GCLHG-TCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATC-TNTGQGSYTCSC 316
Query: 404 PQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSD 463
GY GA C +DEC + +PC++ G C + + ++ C C G+ G CE+ C
Sbjct: 317 RPGYTGATCELGIDEC---DPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADG 373
Query: 464 PCQNDATCLDKI-GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPP 522
PC N C D GG++C C G+ G +CE +I+ C S+PC N +CVD + + C C
Sbjct: 374 PCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQA 433
Query: 523 GFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG 582
GF+G C ++DDC+S+PC NG C D N + C C G+TG C + C+ PCH+G
Sbjct: 434 GFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNG 493
Query: 583 -QCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLND 619
C + Y C C GY G C + E P + D
Sbjct: 494 ATCHERGHRYVCECARGYGGPNCQFLLPELPPGPAVVD 531
Score = 234 bits (598), Expect = 6e-61
Identities = 129/350 (36%), Positives = 173/350 (49%), Gaps = 34/350 (9%)
Query: 473 DKIGGFTC------LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTG 526
D G FTC +C PG+KG +C I C +G C DK +C C G+ G
Sbjct: 197 DAFGHFTCGERGEKVCNPGWKGPYCTEPI--CLPGCDEQHGFC-DKPG--ECKCRVGWQG 251
Query: 527 PVCQIDIDDCSSTP-CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQ 585
C D+C P CL+G P ++C C G+ G+ C ++++ C HH C+
Sbjct: 252 RYC----DECIRYPGCLHGT--CQQP--WQCNCQEGWGGLFCNQDLNYCT----HHKPCK 299
Query: 586 DGID-------SYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTS 638
+G SYTC C PGY GA C IDEC SPC N G C DL N Y C C PG
Sbjct: 300 NGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFY 359
Query: 639 GVNCEINFDDCASNPCIH-GICMDGIN-RYSCVCSPGFTGQRCNIDIDECASNPCRKGAT 696
G CE++ CA PC + G C D + YSC C G++G C ID C+S+PC GA
Sbjct: 360 GKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAK 419
Query: 697 CINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCE 755
C++ + + C C G C V++C S+PC + G C G++ + C C G+ G NC
Sbjct: 420 CVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCS 479
Query: 756 VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCL 805
+ C PC NG TC + Y C C +G+ G NCQ + E P +
Sbjct: 480 APVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGPAV 529
Score = 233 bits (595), Expect = 1e-60
Identities = 126/398 (31%), Positives = 190/398 (47%), Gaps = 36/398 (9%)
Query: 856 SYTCLCAPGWQGQRCTIDIDECISKP---CMNHGLCHNTQGSYMCECPPGFSGMDCEEDI 912
SY +C + G+ C++ +P H C +G +C PG+ G C E I
Sbjct: 174 SYRFVCDEHYYGEGCSV-----FCRPRDDAFGHFTC-GERGEKVCN--PGWKGPYCTEPI 225
Query: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972
CL + G C C C G+ G C +EC+ P GTC +
Sbjct: 226 --CLPGCDEQHGFCD---KPGECKCRVGWQGRYC----DECIRYPGCLHGTCQQ---PWQ 273
Query: 973 CKCQAGFDGVHCENNINECTESS-CFNGGTCVD-GINSFSCLCPVGFTGSFCLHEINECS 1030
C CQ G+ G+ C ++N CT C NG TC + G S++C C G+TG+ C I+EC
Sbjct: 274 CNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECD 333
Query: 1031 SHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES-QCLC 1089
PC N G+C D +Y C+CP G+ GK C+ C+ PC N G C C C
Sbjct: 334 PSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRC 393
Query: 1090 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQ 1149
P G++G C+ C + C + C++ G+ + C+C G++G +C++
Sbjct: 394 PVGYSGFNCEKKIDYCSSSP----------CSNGAKCVDLGDAYLCRCQAGFSGRHCDDN 443
Query: 1150 LDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHF 1209
+D+CAS+PC +G TC D + + C C PGY G NC V C++ PC NG TC + + +
Sbjct: 444 VDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRY 503
Query: 1210 KCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGG 1247
C C G G C+ + + GP ++ + ++ GG
Sbjct: 504 VCECARGYGGPNCQFLLPELPPGPAVVDLTEKLEGQGG 541
Score = 232 bits (591), Expect = 4e-60
Identities = 119/324 (36%), Positives = 164/324 (50%), Gaps = 22/324 (6%)
Query: 53 CPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVS 112
C G+ G YC C + G C C+C G+ G C +P
Sbjct: 212 CNPGWKGPYCTE-PICLPGCDEQHGFCDKPG-----ECKCRVGWQGRYCDECIRYP---- 261
Query: 113 RPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACLSH-PCANGSTCT-TVANQFSCK 169
CL+G TC + ++C CQ G+ G C Q + C H PC NG+TCT T ++C
Sbjct: 262 -GCLHG-TC----QQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCS 315
Query: 170 CLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSP 229
C G+TG CE ++ECD P C++GG+C +L SY C CP GF G+ C+ + CA P
Sbjct: 316 CRPGYTGATCELGIDECD-PSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGP 374
Query: 230 CVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQ 289
C NGG C + D + C C G+ G CE+ ID C + C NG CVD + Y CRC
Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAG 434
Query: 290 WTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTP 349
++G+ C ++VD+C P C NGGTC + + C C G++G +CS + C A C
Sbjct: 435 FSGRHCDDNVDDCASSP--CANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHN 492
Query: 350 GSTCIDRVASFSCMCPEGKAGLLC 373
G+TC +R + C C G G C
Sbjct: 493 GATCHERGHRYVCECARGYGGPNC 516
Score = 231 bits (590), Expect = 5e-60
Identities = 119/318 (37%), Positives = 159/318 (50%), Gaps = 23/318 (7%)
Query: 28 CRDGYE-PCVNEGMCVT-------YHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTC 79
C G++ P E +C+ + + G CKC G+ G YC D C + GTC
Sbjct: 212 CNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYC---DECIRYPGCLHGTC 268
Query: 80 VAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTG 139
C C G+ G C ++ C +PC NG TC + +Y C+C+ G+TG
Sbjct: 269 QQPWQ-----CNCQEGWGGLFCNQDLNY-CTHHKPCKNGATCTNTGQGSYTCSCRPGYTG 322
Query: 140 KECQ-WTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTC 198
C+ D C PC NG +CT + N +SC C GF G+ CE C G C +GG C
Sbjct: 323 ATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTC-ADGPCFNGGRC 381
Query: 199 LNLP-GSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC 257
+ P G Y C+CP G++G C+ C+ SPC NG C GD + C C GF G C
Sbjct: 382 SDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGD-AYLCRCQAGFSGRHC 440
Query: 258 ERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCAN 317
+ N+DDC + C NGG C DGVN ++C CPP +TG+ C+ V C P C NG TC
Sbjct: 441 DDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAP--CHNGATCHE 498
Query: 318 RNGGYGCVCVNGWSGDDC 335
R Y C C G+ G +C
Sbjct: 499 RGHRYVCECARGYGGPNC 516
Score = 227 bits (579), Expect = 1e-58
Identities = 123/349 (35%), Positives = 166/349 (47%), Gaps = 37/349 (10%)
Query: 1004 DGINSFSC------LCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTG 1057
D F+C +C G+ G +C I C G C D G C C +G+ G
Sbjct: 197 DAFGHFTCGERGEKVCNPGWKGPYCTEPI--CLPGCDEQHGFC-DKPG--ECKCRVGWQG 251
Query: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVE 1117
+ C C R P GTC Q QC C GW G +C+ C
Sbjct: 252 RYCDE----CIRYPGCLHGTCQQPW---QCNCQEGWGGLFCNQDLNYC----------TH 294
Query: 1118 HL-CQHSGVCINAGNTHY-CQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCEC 1175
H C++ C N G Y C C GYTG+ CE +DEC +PC++G +C+D Y C C
Sbjct: 295 HKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTC 354
Query: 1176 VPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNH-FKCSCPPGTRGLLCEENIDDCARGPH 1234
PG+ G CE C + PC NGG C D + + C CP G G CE+ ID C+ P
Sbjct: 355 PPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSP- 413
Query: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRS 1294
C NG +C+D Y CRC GF+G C+ ++++C S+PC++ G+ C ND+ C C
Sbjct: 414 CSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGT--CRDGVNDFSCTCPP 471
Query: 1295 AFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
+TGR+C V C PC NG TC + ++C C G+ G CQ
Sbjct: 472 GYTGRNCSAPVSRCEHAPCHNGATCHERGHR---YVCECARGYGGPNCQ 517
Score = 226 bits (575), Expect = 3e-58
Identities = 124/353 (35%), Positives = 170/353 (48%), Gaps = 24/353 (6%)
Query: 122 HMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCET 181
H + E C G+ G C CL C CKC G+ G+ C+
Sbjct: 201 HFTCGERGEKVCNPGWKGPYCT-EPICLPGCDEQHGFCDKPGE---CKCRVGWQGRYCD- 255
Query: 182 DVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAP-SPCVNGGTCRQTG 240
EC C HG TC +QC C +G+ G +C+ C PC NG TC TG
Sbjct: 256 ---ECIRYPGCLHG-TCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTG 308
Query: 241 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD 300
++ C+C PG+ G+TCE ID+C C+NGG C D N+Y+C CPP + G+ C
Sbjct: 309 QGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAM 368
Query: 301 ECLLQPNACQNGGTCANR-NGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVAS 359
C P C NGG C++ +GGY C C G+SG +C + ID C+ + C+ G+ C+D +
Sbjct: 369 TCADGP--CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDA 426
Query: 360 FSCMCPEGKAGLLC--HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD 417
+ C C G +G C ++DD C S+PC G C + CTCP GY G +C+ V
Sbjct: 427 YLCRCQAGFSGRHCDDNVDD-CASSPCANGGTCRDGV--NDFSCTCPPGYTGRNCSAPVS 483
Query: 418 ECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDAT 470
C A PC + C + CEC +GY GP C+ + E P D T
Sbjct: 484 RCEHA---PCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGPAVVDLT 533
Score = 225 bits (573), Expect = 5e-58
Identities = 117/345 (33%), Positives = 164/345 (47%), Gaps = 32/345 (9%)
Query: 975 CQAGFDGVHCENNINECTESSCFNGGTCVDGI--NSFSCLCPVGFTGSFCLHEINECSSH 1032
C G+ G +C TE C G G C C VG+ G +C +EC +
Sbjct: 212 CNPGWKGPYC-------TEPICLPGCDEQHGFCDKPGECKCRVGWQGRYC----DECIRY 260
Query: 1033 PCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSR-SPCKNKGTCVQKKAESQ-CLCP 1090
P GTC ++C+C G+ G C +N C+ PCKN TC S C C
Sbjct: 261 PGCLHGTCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCR 317
Query: 1091 SGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQL 1150
G+ GA C++ CD + C++ G C + N++ C CP G+ G CE
Sbjct: 318 PGYTGATCELGIDECDPSP----------CKNGGSCTDLENSYSCTCPPGFYGKICELSA 367
Query: 1151 DECASNPCQHGATCSDFI-GGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHF 1209
CA PC +G CSD GGY C C GY G NCE ++D C + PC NG C+DL + +
Sbjct: 368 MTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAY 427
Query: 1210 KCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECL 1269
C C G G C++N+DDCA P C NGG C D + +SC C PG+ G C ++ C
Sbjct: 428 LCRCQAGFSGRHCDDNVDDCASSP-CANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCE 486
Query: 1270 SNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCL 1314
PC + + C + + Y+C C + G +C+ + P P +
Sbjct: 487 HAPCHNGAT--CHERGHRYVCECARGYGGPNCQFLLPELPPGPAV 529
Score = 207 bits (528), Expect = 8e-53
Identities = 127/391 (32%), Positives = 171/391 (43%), Gaps = 53/391 (13%)
Query: 1046 TYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNV-- 1103
+YR C Y G+ C R TC ++ + +C GW G YC P
Sbjct: 174 SYRFVCDEHYYGEGCSVFCR--PRDDAFGHFTCGER---GEKVCNPGWKGPYCTEPICLP 228
Query: 1104 SCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNP-CQHGA 1162
CD + G C G C+C +G+ G YC DEC P C HG
Sbjct: 229 GCD--------------EQHGFCDKPGE---CKCRVGWQGRYC----DECIRYPGCLHG- 266
Query: 1163 TCSDFIGGYRCECVPGYQGVNCEYEVDEC-QNQPCQNGGTCIDL-VNHFKCSCPPGTRGL 1220
TC ++C C G+ G+ C +++ C ++PC+NG TC + + CSC PG G
Sbjct: 267 TCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGA 323
Query: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLD 1280
CE ID+C P C NGG C D YSC C PGF G+ CE C PC + G
Sbjct: 324 TCELGIDECDPSP-CKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCS 382
Query: 1281 CIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGA 1340
Y C C ++G +CE +D C PC NG C ++ D ++CRC GFSG
Sbjct: 383 DSP-DGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCV---DLGDAYLCRCQAGFSGR 438
Query: 1341 RCQSS---CGQVKCRKGEQCVHTASGPRCFCP---SPRDCE---SGCASSPCQHGGSCHP 1391
C + C C G C + C CP + R+C S C +PC +G +CH
Sbjct: 439 HCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHE 498
Query: 1392 QRQPPYYSCQCAPPFSGSRCELYTAPPSTPP 1422
+ Y C+CA + G C+ P PP
Sbjct: 499 RGH--RYVCECARGYGGPNCQFLL--PELPP 525
Score = 169 bits (428), Expect = 3e-41
Identities = 79/236 (33%), Positives = 120/236 (50%), Gaps = 8/236 (3%)
Query: 32 YEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATC 90
++PC N C G+ C C G+ G C+ D C+ + C+NGG+C + +C
Sbjct: 295 HKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCT--DLENSYSC 352
Query: 91 RCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ-WTDACL 149
C GF G+ C+ S PC NGG C Y C C VG++G C+ D C
Sbjct: 353 TCPPGFYGKICELSAM--TCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCS 410
Query: 150 SHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC 209
S PC+NG+ C + + + C+C GF+G+ C+ +V++C C +GGTC + + C C
Sbjct: 411 SSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDC-ASSPCANGGTCRDGVNDFSCTC 469
Query: 210 PQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCP 265
P G+TG+ C + C +PC NG TC + G + C C G+ G C+ + + P
Sbjct: 470 PPGYTGRNCSAPVSRCEHAPCHNGATCHERG-HRYVCECARGYGGPNCQFLLPELP 524
Score = 132 bits (333), Expect = 3e-30
Identities = 95/313 (30%), Positives = 128/313 (40%), Gaps = 49/313 (15%)
Query: 1175 CVPGYQGVNCEYEV-----DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDC 1229
C PG++G C + DE Q+ C G +C C G +G C D+C
Sbjct: 212 CNPGWKGPYCTEPICLPGCDE-QHGFCDKPG---------ECKCRVGWQGRYC----DEC 257
Query: 1230 ARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYL 1289
R P CL+G C + C C G+ G C D+N C + G+ Y
Sbjct: 258 IRYPGCLHG-TCQQP---WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYT 313
Query: 1290 CVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS---C 1346
C CR +TG CE +D C PC NGG+C +++ + + C CPPGF G C+ S C
Sbjct: 314 CSCRPGYTGATCELGIDECDPSPCKNGGSC---TDLENSYSCTCPPGFYGKICELSAMTC 370
Query: 1347 GQVKCRKGEQCVHTASGP-RCFCP---SPRDCESG---CASSPCQHGGSCHPQRQPPYYS 1399
C G +C + G C CP S +CE C+SSPC +G C Y
Sbjct: 371 ADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDA--YL 428
Query: 1400 CQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTM 1459
C+C FSG C+ C S CA+ G C + N +C G
Sbjct: 429 CRCQAGFSGRHCD-------DNVDDCASSPCAN---GGTCRDGVNDFSCTCPPGYTGRNC 478
Query: 1460 ENPWANCSSPLPC 1472
P + C PC
Sbjct: 479 SAPVSRCEH-APC 490
Score = 114 bits (285), Expect = 1e-24
Identities = 61/159 (38%), Positives = 81/159 (50%), Gaps = 11/159 (6%)
Query: 25 ALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQA 83
A+ C DG PC N G C +G C+CP G+ G C+ + D C + C NG CV
Sbjct: 367 AMTCADG--PCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVD-- 422
Query: 84 MLGKA-TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC 142
LG A CRC +GF+G C + S PC NGGTC D + CTC G+TG+ C
Sbjct: 423 -LGDAYLCRCQAGFSGRHCDDNVDD--CASSPCANGGTCRDGVND-FSCTCPPGYTGRNC 478
Query: 143 QW-TDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE 180
C PC NG+TC +++ C+C G+ G C+
Sbjct: 479 SAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQ 517
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 271 bits (692), Expect = 8e-72
Identities = 154/454 (33%), Positives = 210/454 (46%), Gaps = 45/454 (9%)
Query: 633 CQPGT-----SGVNCEI----NFDDCASNPCIHGICMDGINRYSCVCSPG--FTGQRCNI 681
C+PG+ VNC + N + C G D + C P +T +
Sbjct: 988 CRPGSVLRGRMCVNCPLGTYYNLEHFTCESCRIGSYQDEEGQLECKLCPSGMYTEYIHSR 1047
Query: 682 DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGY 741
+I +C + C++G +G+ CP G + P S+ CLS P G
Sbjct: 1048 NISDCKAQ-CKQGTYSYSGLETCES-CPLGTYQPKFGSR--SCLSCPENTSTVKRGAVNI 1103
Query: 742 KCLCDAGWVGINCEVDKNECLS----NPCQNGGTCDNLVNGYRCTCK-KGFKGYNCQVNI 796
G+ C K +PC N + C G + +I
Sbjct: 1104 SAC------GVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSI 1157
Query: 797 DECASNPCLNQGTCFDDISGYTCHCVLPYTGKN--------CQTVLAPCSPNPCENAAVC 848
EC+S F V+P V C NPC N+ C
Sbjct: 1158 TECSS---------FSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTC 1208
Query: 849 KESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDC 908
++ Y CLC G+ G +C DIDEC PC+N+G+C + G ++CECP G++G C
Sbjct: 1209 QQLGR--GYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRC 1266
Query: 909 EEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYV 968
EE+I++C ++PC N G C+DGV + C C+ GF G C+T++NEC S PC N C D V
Sbjct: 1267 EENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQV 1326
Query: 969 NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINE 1028
+ CKC GF G C N++EC C NG TC DG NSF CLC GFTGS C INE
Sbjct: 1327 GGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINE 1386
Query: 1029 CSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQT 1062
C S+PC N+ TCVD L +Y C C G++GK C+T
Sbjct: 1387 CQSNPCRNQATCVDELNSYSCKCQPGFSGKRCET 1420
Score = 264 bits (675), Expect = 7e-70
Identities = 156/447 (34%), Positives = 206/447 (46%), Gaps = 43/447 (9%)
Query: 189 PGHCQHGGTCLNLP-----------------GSYQCQ--------CPQGFTGQYCDSLYV 223
PG G C+N P GSYQ + CP G +Y S +
Sbjct: 990 PGSVLRGRMCVNCPLGTYYNLEHFTCESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNI 1049
Query: 224 PCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYN 283
+ C G T +G T E L ++ R+ CP + V VN
Sbjct: 1050 SDCKAQCKQG-TYSYSGLETCESCPLGTYQPKFGSRSCLSCPEN---TSTVKRGAVNISA 1105
Query: 284 CRCP-PQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVC-VNGWSGDDCSENIDD 341
C P P+ G+F + C + C N + C G + S +I +
Sbjct: 1106 CGVPCPE--GKFSRSGLMPC----HPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITE 1159
Query: 342 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYIC 401
C+ S T + V S + + + + C NPCH C L Y+C
Sbjct: 1160 CSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQ--LGRGYVC 1217
Query: 402 TCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECH 461
CP GY G C D+DEC+ PC + G C + G F CEC GY G RCE +INEC
Sbjct: 1218 LCPLGYTGLKCETDIDECSPL---PCLNNGVCKDLVGEFICECPSGYTGQRCEENINECS 1274
Query: 462 SDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCP 521
S PC N C+D + G+ C C+ GF G+HCE E+NECQSNPC+NN C D+V F C CP
Sbjct: 1275 SSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCP 1334
Query: 522 PGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPC-H 580
PGF G C ++D+C S PC NGA C D N + C CA GFTG CE NI+ C +PC +
Sbjct: 1335 PGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRN 1394
Query: 581 HGQCQDGIDSYTCICNPGYMGAICSDQ 607
C D ++SY+C C PG+ G C +
Sbjct: 1395 QATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 243 bits (619), Expect = 2e-63
Identities = 103/235 (43%), Positives = 148/235 (62%), Gaps = 4/235 (1%)
Query: 719 SQV-NECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLV 776
SQV +EC NPC + G C GY CLC G+ G+ CE D +EC PC N G C +LV
Sbjct: 1191 SQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLV 1250
Query: 777 NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAP 836
+ C C G+ G C+ NI+EC+S+PCLN+G C D ++GY C CV + G +C+T +
Sbjct: 1251 GEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNE 1310
Query: 837 CSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYM 896
C NPC N AVC++ + C C PG+ G RC ++DEC+S+PC N C + S+
Sbjct: 1311 CQSNPCLNNAVCEDQVG--GFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1368
Query: 897 CECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMN 951
C C GF+G CE +I++C +NPC+N +C+D +N++SC C PGF+G +C+T+ +
Sbjct: 1369 CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQS 1423
Score = 241 bits (616), Expect = 5e-63
Identities = 101/232 (43%), Positives = 146/232 (62%), Gaps = 2/232 (0%)
Query: 603 ICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIH-GICMD 661
I S EC+ +PC N G C L GY C C G +G+ CE + D+C+ PC++ G+C D
Sbjct: 1189 ISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKD 1248
Query: 662 GINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV 721
+ + C C G+TGQRC +I+EC+S+PC C++GV G+RC C +G C ++V
Sbjct: 1249 LVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEV 1308
Query: 722 NECLSNPCIHGN-CTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780
NEC SNPC++ C + G+ C C G++G C + +ECLS PC+NG TC + N +R
Sbjct: 1309 NECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1368
Query: 781 CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQT 832
C C GF G +C++NI+EC SNPC NQ TC D+++ Y+C C ++GK C+T
Sbjct: 1369 CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCET 1420
Score = 241 bits (615), Expect = 6e-63
Identities = 98/224 (43%), Positives = 128/224 (57%)
Query: 876 ECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSC 935
EC PC N G C Y+C CP G++G+ CE DID+C PC N G C D V F C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Query: 936 LCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESS 995
C G+TG +C+ ++NEC S PC N G C D V Y C C GF G+HCE +NEC +
Sbjct: 1256 ECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP 1315
Query: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
C N C D + F C CP GF G+ C ++EC S PC N TC DG ++RC C G+
Sbjct: 1316 CLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGF 1375
Query: 1056 TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCD 1099
TG +C+ +N C +PC+N+ TCV + C C G++G C+
Sbjct: 1376 TGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 230 bits (587), Expect = 1e-59
Identities = 127/368 (34%), Positives = 171/368 (46%), Gaps = 37/368 (10%)
Query: 842 CENAAVCKESPNFESYTCLCAPGWQG--QRCTIDIDECISKPCMNHGLCHNTQGSYMCE- 898
CE+ + P F S +CL P +R ++I C PC + G C
Sbjct: 1069 CESCPLGTYQPKFGSRSCLSCPENTSTVKRGAVNISAC-GVPCPEGKFSRS--GLMPCHP 1125
Query: 899 CPPGFSGMDCEEDIDDCLANPCQN----GGS-----CMDGVNTFSC----LCLPGFTG-- 943
CP + + + CLA P GS C +TFS + P G
Sbjct: 1126 CPRDYYQPNAGKAF--CLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHI 1183
Query: 944 ----DKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNG 999
+ +EC PC N GTC Y C C G+ G+ CE +I+EC+ C N
Sbjct: 1184 KKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNN 1243
Query: 1000 GTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKN 1059
G C D + F C CP G+TG C INECSS PCLN+G CVDG+ YRC+C G+ G +
Sbjct: 1244 GVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLH 1303
Query: 1060 CQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHL 1119
C+T VN C +PC N C + C CP G+ G C C +
Sbjct: 1304 CETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDEC----------LSQP 1353
Query: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179
C++ C + N+ C C G+TGS+CE ++EC SNPC++ ATC D + Y C+C PG+
Sbjct: 1354 CKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1413
Query: 1180 QGVNCEYE 1187
G CE E
Sbjct: 1414 SGKRCETE 1421
Score = 229 bits (584), Expect = 3e-59
Identities = 149/478 (31%), Positives = 203/478 (42%), Gaps = 56/478 (11%)
Query: 837 CSPNPCENAAVCKESP-----NFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNT 891
C P +C P N E +TC + C I G +
Sbjct: 988 CRPGSVLRGRMCVNCPLGTYYNLEHFTC--------ESCRI-------------GSYQDE 1026
Query: 892 QGSYMCE-CPPG-FSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTD 949
+G C+ CP G ++ +I DC A C+ G G+ T L + + +
Sbjct: 1027 EGQLECKLCPSGMYTEYIHSRNISDCKAQ-CKQGTYSYSGLETCESCPLGTY---QPKFG 1082
Query: 950 MNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSF 1009
CLS P VN C +G + + C C + +F
Sbjct: 1083 SRSCLSCPENTSTVKRGAVNISACGVPCP-EGKFSRSGLMPC--HPCPRDYYQPNAGKAF 1139
Query: 1010 SCLCPVGFTGSFC-LHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQT---LVN 1065
CP T F I ECSS T + LG+ K + + +
Sbjct: 1140 CLACPFYGTTPFAGSRSITECSSF----SSTFSAAEESVVPPASLGHIKKRHEISSQVFH 1195
Query: 1066 LCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGV 1125
C +PC N GTC Q CLCP G+ G C+ C C ++GV
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLP----------CLNNGV 1245
Query: 1126 CINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE 1185
C + C+CP GYTG CEE ++EC+S+PC + C D + GYRC CV G+ G++CE
Sbjct: 1246 CKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCE 1305
Query: 1186 YEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRI 1245
EV+ECQ+ PC N C D V F C CPPG G C +N+D+C P C NG C D
Sbjct: 1306 TEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQP-CKNGATCKDGA 1364
Query: 1246 GGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCET 1303
+ C C GF G CE +INEC SNPC ++ + C+ N Y C C+ F+G+ CET
Sbjct: 1365 NSFRCLCAAGFTGSHCELNINECQSNPCRNQAT--CVDELNSYSCKCQPGFSGKRCET 1420
Score = 229 bits (583), Expect = 3e-59
Identities = 99/228 (43%), Positives = 133/228 (58%), Gaps = 3/228 (1%)
Query: 535 DCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPC-HHGQCQDGIDSYTC 593
+C PC N C GY C C G+TG+ CE +ID C P PC ++G C+D + + C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Query: 594 ICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP 653
C GY G C + I+EC SSPCLN G C+D V GY+C C G G++CE ++C SNP
Sbjct: 1256 ECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP 1315
Query: 654 CI-HGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGP 712
C+ + +C D + + C C PGF G RC ++DEC S PC+ GATC +G N FRC+C G
Sbjct: 1316 CLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGF 1375
Query: 713 HHPSCYSQVNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKN 759
C +NEC SNPC + C L+ Y C C G+ G CE +++
Sbjct: 1376 TGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQS 1423
Score = 228 bits (580), Expect = 7e-59
Identities = 96/225 (42%), Positives = 131/225 (58%), Gaps = 6/225 (2%)
Query: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179
C +SG C G + C CPLGYTG CE +DEC+ PC + C D +G + CEC GY
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1261
Query: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGG 1239
G CE ++EC + PC N G C+D V ++C+C G GL CE +++C P CLN
Sbjct: 1262 TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP-CLNNA 1320
Query: 1240 QCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGR 1299
C D++GG+ C+C PGF G RC +++ECLS PC + + C N + C+C + FTG
Sbjct: 1321 VCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGAT--CKDGANSFRCLCAAGFTGS 1378
Query: 1300 HCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQS 1344
HCE ++ C PC N TC N + C+C PGFSG RC++
Sbjct: 1379 HCELNINECQSNPCRNQATCVDELN---SYSCKCQPGFSGKRCET 1420
Score = 210 bits (535), Expect = 1e-53
Identities = 91/231 (39%), Positives = 132/231 (57%), Gaps = 4/231 (1%)
Query: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQC 207
C +PC N TC + + C C G+TG KCETD++EC P C + G C +L G + C
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECS-PLPCLNNGVCKDLVGEFIC 1255
Query: 208 QCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNH 267
+CP G+TGQ C+ C+ SPC+N G C G + C C+ GF G CE +++C ++
Sbjct: 1256 ECPSGYTGQRCEENINECSSSPCLNKGICVD-GVAGYRCTCVKGFVGLHCETEVNECQSN 1314
Query: 268 RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCV 327
C N VC D V + C+CPP + G C ++VDECL QP C+NG TC + + C+C
Sbjct: 1315 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGANSFRCLCA 1372
Query: 328 NGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDA 378
G++G C NI++C C +TC+D + S+SC C G +G C + +
Sbjct: 1373 AGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQS 1423
Score = 209 bits (531), Expect = 4e-53
Identities = 149/451 (33%), Positives = 193/451 (42%), Gaps = 65/451 (14%)
Query: 987 NINECTESSCFNGGTCVDGINSFSC-LCPVG-FTGSFCLHEINECSSHPCLNEGTCVDGL 1044
N+ T SC G+ D C LCP G +T I++C + C GL
Sbjct: 1009 NLEHFTCESC-RIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQ-CKQGTYSYSGL 1066
Query: 1045 GTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCL-CPSGWAGAYCDVPNV 1103
T SCPLG T K CL CP + N+
Sbjct: 1067 ETCE-SCPLG----------------------TYQPKFGSRSCLSCPENTSTVKRGAVNI 1103
Query: 1104 S-CDIAA-----SRRGVLVEHLCQHSGVCINAGNTHYCQCPL-GYTGSYCEEQLDECASN 1156
S C + SR G++ H C NAG CP G T + EC+S
Sbjct: 1104 SACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSS- 1162
Query: 1157 PCQHGATCSDFIGGYRCECVPGYQG-VNCEYEVD-----ECQNQPCQNGGTCIDLVNHFK 1210
S F P G + +E+ EC PC N GTC L +
Sbjct: 1163 ------FSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYV 1216
Query: 1211 CSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLS 1270
C CP G GL CE +ID+C+ P CLN G C D +G + C C G+ G+RCE +INEC S
Sbjct: 1217 CLCPLGYTGLKCETDIDECSPLP-CLNNGVCKDLVGEFICECPSGYTGQRCEENINECSS 1275
Query: 1271 NPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFI 1330
+PC ++G C+ Y C C F G HCET V+ C PCLN C + GF+
Sbjct: 1276 SPCLNKGI--CVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVC---EDQVGGFL 1330
Query: 1331 CRCPPGFSGARCQSS---CGQVKCRKGEQCVHTASGPRCFCPSP---RDCE---SGCASS 1381
C+CPPGF G RC + C C+ G C A+ RC C + CE + C S+
Sbjct: 1331 CKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSN 1390
Query: 1382 PCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412
PC++ +C + YSC+C P FSG RCE
Sbjct: 1391 PCRNQATCVDELNS--YSCKCQPGFSGKRCE 1419
Score = 202 bits (513), Expect = 4e-51
Identities = 91/231 (39%), Positives = 129/231 (55%), Gaps = 9/231 (3%)
Query: 107 HPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQ 165
H CF + PC N GTC L R Y C C +G+TG +C+ D C PC N C + +
Sbjct: 1195 HECFFN-PCHNSGTCQQLGRG-YVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGE 1252
Query: 166 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC 225
F C+C +G+TGQ+CE ++NEC C + G C++ Y+C C +GF G +C++ C
Sbjct: 1253 FICECPSGYTGQRCEENINECS-SSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNEC 1311
Query: 226 APSPCVNGGTCR-QTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNC 284
+PC+N C Q G F C C PGF G+ C +N+D+C + C+NG C DG N++ C
Sbjct: 1312 QSNPCLNNAVCEDQVGGFL--CKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRC 1369
Query: 285 RCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDC 335
C +TG C +++EC Q N C+N TC + Y C C G+SG C
Sbjct: 1370 LCAAGFTGSHCELNINEC--QSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 197 bits (502), Expect = 8e-50
Identities = 130/408 (31%), Positives = 170/408 (41%), Gaps = 67/408 (16%)
Query: 51 CK-CPEGFLGEYCQHRDPCE-KNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 108
CK CP G EY R+ + K +C+ G + G TC E C T P
Sbjct: 1032 CKLCPSGMYTEYIHSRNISDCKAQCKQG----TYSYSGLETC--------ESCPLGTYQP 1079
Query: 109 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLS-----HPCANGSTCTTVA 163
F SR CL +C + + G C S HPC
Sbjct: 1080 KFGSRSCL---SCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAG 1136
Query: 164 NQFSCKC----LTGFTGQKCETD----------VNECDIP----GH-------------- 191
F C T F G + T+ E +P GH
Sbjct: 1137 KAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHE 1196
Query: 192 -----CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQ-TGDFTFE 245
C + GTC L Y C CP G+TG C++ C+P PC+N G C+ G+F
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI-- 1254
Query: 246 CNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQ 305
C C G+ G CE NI++C + C N G+CVDGV Y C C + G C +V+EC Q
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNEC--Q 1312
Query: 306 PNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCP 365
N C N C ++ GG+ C C G+ G C +N+D+C C G+TC D SF C+C
Sbjct: 1313 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1372
Query: 366 EGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADC 412
G G C L+ + C SNPC A C + LN Y C C G+ G C
Sbjct: 1373 AGFTGSHCELNINECQSNPCRNQATC-VDELN-SYSCKCQPGFSGKRC 1418
Score = 140 bits (352), Expect = 2e-32
Identities = 71/189 (37%), Positives = 96/189 (50%), Gaps = 9/189 (4%)
Query: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRC 92
PC+N G+C G C+CP G+ G+ C+ + C + C N G CV + C C
Sbjct: 1239 PCLNNGVCKDLV-GEFICECPSGYTGQRCEENINECSSSPCLNKGICVDG--VAGYRCTC 1295
Query: 93 ASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACLSH 151
GF G C+ + S PCLN C + C C GF G C + D CLS
Sbjct: 1296 VKGFVGLHCETEVNE--CQSNPCLNNAVCED-QVGGFLCKCPPGFLGTRCGKNVDECLSQ 1352
Query: 152 PCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQ 211
PC NG+TC AN F C C GFTG CE ++NEC C++ TC++ SY C+C
Sbjct: 1353 PCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQ-SNPCRNQATCVDELNSYSCKCQP 1411
Query: 212 GFTGQYCDS 220
GF+G+ C++
Sbjct: 1412 GFSGKRCET 1420
Score = 122 bits (307), Expect = 3e-27
Identities = 124/457 (27%), Positives = 179/457 (39%), Gaps = 81/457 (17%)
Query: 1050 SCPLGYTGKNCQTLVNLCSRSPCKNK--GTCVQKKAESQC-LCPSGWAGAYCDVPNVSCD 1106
+CPLG T NL C++ G+ ++ + +C LCPSG Y N+S
Sbjct: 1001 NCPLG-------TYYNL-EHFTCESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDC 1052
Query: 1107 IAASRRGVLVEHLCQHSGVCINAGNTHYCQ-CPLG-YTGSYCEEQLDECASNPC--QHGA 1162
A ++G +SG+ C+ CPLG Y + C N + GA
Sbjct: 1053 KAQCKQGTY-----SYSGL-------ETCESCPLGTYQPKFGSRSCLSCPENTSTVKRGA 1100
Query: 1163 TCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCP-PGTRGLL 1221
G VP +G + C PC + F +CP GT
Sbjct: 1101 VNISACG------VPCPEGKFSRSGLMPCH--PCPRDYYQPNAGKAFCLACPFYGTTPFA 1152
Query: 1222 CEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAG------ERCEGDINECLSNPCSS 1275
+I +C+ + + P G E +EC NPC +
Sbjct: 1153 GSRSITECSSFSSTFSAAE--------ESVVPPASLGHIKKRHEISSQVFHECFFNPCHN 1204
Query: 1276 EGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPP 1335
G+ C QL Y+C+C +TG CET +D C +PCLN G C ++ FIC CP
Sbjct: 1205 SGT--CQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVC---KDLVGEFICECPS 1259
Query: 1336 GFSGARCQ---SSCGQVKCRKGEQCVHTASGPRCFCPS---PRDCE---SGCASSPCQHG 1386
G++G RC+ + C C CV +G RC C CE + C S+PC +
Sbjct: 1260 GYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNN 1319
Query: 1387 GSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSH 1446
C + Q + C+C P F G+RC CLSQ C + A C + NS
Sbjct: 1320 AVC--EDQVGGFLCKCPPGFLGTRC-------GKNVDECLSQPCKNGA---TCKDGANSF 1367
Query: 1447 AC----QWDGGDCSLTMENPWAN-CSSPLPCWDYINN 1478
C + G C L + +N C + C D +N+
Sbjct: 1368 RCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNS 1404
Score = 76.3 bits (186), Expect = 4e-13
Identities = 110/463 (23%), Positives = 163/463 (35%), Gaps = 95/463 (20%)
Query: 153 CANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQH---GGTCLNLPGSYQCQC 209
C G T T + F+C+ + ++ +C +P + H G ++ C
Sbjct: 3148 CLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSC 3207
Query: 210 PQGFTGQ-------YCDSLYVP------CAPSPCVNGGT--------CRQTGDFTFECNC 248
+G+T + D + P C+P C + + T + T C
Sbjct: 3208 AEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQC 3267
Query: 249 LPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNA 308
PG+E + C +R +GGV + C P ++ D++ PN
Sbjct: 3268 EPGYELEGNRERV--CQENRQWSGGVAI--CKETRCETPLEFLNG--KADIENRTTGPNV 3321
Query: 309 CQNGGTCANRNGGYGCVCVNGWSGDDCSENID-DCAFASCTPGSTCIDRVASFSCMCPEG 367
+ C N GY + G S C+EN C P + V + + E
Sbjct: 3322 VYS---C---NRGYS---LEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEK 3372
Query: 368 KAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPC 427
+ + D +S C +G L L G I TC T+ +C + P
Sbjct: 3373 EFYV-----DQNVSIKCREGFL-----LQGHGIITCNPD---ETWTQTSAKCEKISCGPP 3419
Query: 428 EHAGKCVNTDGAFHC------ECLKGY-----------------AGPRCEMDINECHSDP 464
H + + C GY + P C C P
Sbjct: 3420 AHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRA---VCRF-P 3475
Query: 465 CQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF 524
CQN C C C G+ G CE I PC+N G+CV +QC CPPG+
Sbjct: 3476 CQNGGICQRPNA---CSCPEGWMGRLCEEPICIL---PCLNGGRCVAP---YQCDCPPGW 3526
Query: 525 TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLC 567
TG C + C S PCLNG KC+ PN C C + +TG C
Sbjct: 3527 TGSRCHTAV--CQS-PCLNGGKCV-RPN--RCHCLSSWTGHNC 3563
Score = 75.1 bits (183), Expect = 8e-13
Identities = 42/108 (38%), Positives = 52/108 (48%), Gaps = 18/108 (16%)
Query: 229 PCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPP 288
PC NGG C++ C+C G+ G CE I P C NGG CV Y C CPP
Sbjct: 3475 PCQNGGICQRPN----ACSCPEGWMGRLCEEPICILP---CLNGGRCVA---PYQCDCPP 3524
Query: 289 QWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCS 336
WTG C V + + C NGG C N C C++ W+G +CS
Sbjct: 3525 GWTGSRCHTAVCQ-----SPCLNGGKCVRPN---RCHCLSSWTGHNCS 3564
Score = 74.7 bits (182), Expect = 1e-12
Identities = 43/104 (41%), Positives = 53/104 (50%), Gaps = 15/104 (14%)
Query: 881 PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPG 940
PC N G+C C CP G+ G CEE I C+ PC NGG C V + C C PG
Sbjct: 3475 PCQNGGICQRPNA---CSCPEGWMGRLCEEPI--CIL-PCLNGGRC---VAPYQCDCPPG 3525
Query: 941 FTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHC 984
+TG +C T + C S PC NGG C V C C + + G +C
Sbjct: 3526 WTGSRCHTAV--CQS-PCLNGGKC---VRPNRCHCLSSWTGHNC 3563
Score = 73.6 bits (179), Expect = 2e-12
Identities = 42/103 (40%), Positives = 50/103 (48%), Gaps = 15/103 (14%)
Query: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
C NGG C +C CP G+ G C I PCLN G CV Y+C CP G+
Sbjct: 3476 CQNGGICQ---RPNACSCPEGWMGRLCEEPI---CILPCLNGGRCV---APYQCDCPPGW 3526
Query: 1056 TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098
TG C T V +SPC N G CV+ ++C C S W G C
Sbjct: 3527 TGSRCHTAV---CQSPCLNGGKCVR---PNRCHCLSSWTGHNC 3563
Score = 73.2 bits (178), Expect = 3e-12
Identities = 47/146 (32%), Positives = 62/146 (42%), Gaps = 26/146 (17%)
Query: 123 MLSRDTYECTCQVGFTGKEC----QWTD-----ACLSHPCANGSTCTTVANQFSCKCLTG 173
M++ Y GF C WT A PC NG C +C C G
Sbjct: 3437 MITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGICQ---RPNACSCPEG 3493
Query: 174 FTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNG 233
+ G+ CE + C +P C +GG C+ YQC CP G+TG C + SPC+NG
Sbjct: 3494 WMGRLCEEPI--CILP--CLNGGRCV---APYQCDCPPGWTGSRC---HTAVCQSPCLNG 3543
Query: 234 GTCRQTGDFTFECNCLPGFEGSTCER 259
G C + C+CL + G C R
Sbjct: 3544 GKCVRPN----RCHCLSSWTGHNCSR 3565
Score = 70.9 bits (172), Expect = 2e-11
Identities = 43/107 (40%), Positives = 54/107 (50%), Gaps = 18/107 (16%)
Query: 1195 PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLP 1254
PCQNGG C CSCP G G LCEE I C CLNGG+C + Y C C P
Sbjct: 3475 PCQNGGIC---QRPNACSCPEGWMGRLCEEPI--CIL--PCLNGGRC---VAPYQCDCPP 3524
Query: 1255 GFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC 1301
G+ G RC + +PC + G C++ C C S++TG +C
Sbjct: 3525 GWTGSRCHTAV---CQSPCLNGGK--CVRPNR---CHCLSSWTGHNC 3563
Score = 67.4 bits (163), Expect = 2e-10
Identities = 40/109 (36%), Positives = 48/109 (44%), Gaps = 20/109 (18%)
Query: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCA 93
PC N G+C C CPEG++G C+ +P C NGG CVA C C
Sbjct: 3475 PCQNGGIC----QRPNACSCPEGWMGRLCE--EPICILPCLNGGRCVAPYQ-----CDCP 3523
Query: 94 SGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC 142
G+TG C H PCLNGG C +R C C +TG C
Sbjct: 3524 PGWTGSRC-----HTAVCQSPCLNGGKCVRPNR----CHCLSSWTGHNC 3563
Score = 65.1 bits (157), Expect = 8e-10
Identities = 193/846 (22%), Positives = 283/846 (33%), Gaps = 202/846 (23%)
Query: 579 CHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTS 638
C+ G +G S C+ N + GA C + P L +G L G+
Sbjct: 2859 CNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMK------- 2911
Query: 639 GVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCI 698
E+ F C G + G + +C + + +I C C
Sbjct: 2912 ----EVTFH------CHEGYILHGAPKLTCQSDGNW-----DAEIPLCKPVNCGPPEDLA 2956
Query: 699 NGV-NGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVD 757
+G NGF I G H +C +HGN S +CL + W G +
Sbjct: 2957 HGFPNGFSFI--HGGHIQY------QCFPGYKLHGN-----SSRRCLSNGSWSGSSPSCL 3003
Query: 758 KNECLSNPCQNG---GTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDD- 813
C + + G GT + R C KGFK L++ TC D
Sbjct: 3004 PCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLG-------------LSEITCEADG 3050
Query: 814 --ISGYTCHCVLPYTGKNCQTVLAPCSPNP-CENAAVCKESPNFESYTCLCAPGWQGQRC 870
SG+ HC G P PN + KE N +Y+C QG
Sbjct: 3051 QWSSGFP-HCEHTSCGS------LPMIPNAFISETSSWKE--NVITYSCRSGYVIQGSSD 3101
Query: 871 TIDIDECI-SKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDG 929
I ++ + S+P + +C C PP +AN G
Sbjct: 3102 LICTEKGVWSQP---YPVCEPLS----CGSPPS-------------VANAVATG-EAHTY 3140
Query: 930 VNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHC----- 984
+ CL G+T D TD C K+G + ++ KC + H
Sbjct: 3141 ESEVKLRCLEGYTMDT-DTDTFTCQ----KDGRWFPERISCSPKKCPLPENITHILVHGD 3195
Query: 985 ENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEIN--ECSSHPCLNEGTCVD 1042
+ ++N SC G T +G+N C + F + C G V
Sbjct: 3196 DFSVNRQVSVSCAEGYT-FEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVG 3254
Query: 1043 GLGTYRCS----CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098
T+ + C GY + + V C + + G + K E++C P +
Sbjct: 3255 SKYTFESTIIYQCEPGYELEGNRERV--CQENRQWSGGVAICK--ETRCETPLEFLNGKA 3310
Query: 1099 DV------PNV--SCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQ---CPLGYTG---- 1143
D+ PNV SC+ S G H C +G + C+ CP+ +
Sbjct: 3311 DIENRTTGPNVVYSCNRGYSLEGPSEAH-CTENGTWSHP--VPLCKPNPCPVPFVIPENA 3367
Query: 1144 --SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQP-CQNGG 1200
S E +D+ S C+ G + G+ + C + Q C+
Sbjct: 3368 LLSEKEFYVDQNVSIKCREGFL------------LQGHGIITCNPDETWTQTSAKCE--- 3412
Query: 1201 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER 1260
K SC P EN ARG H G YSC ++G
Sbjct: 3413 ---------KISCGPPAH----VENA--IARGVHYQYGDMIT-----YSC-----YSGYM 3447
Query: 1261 CEGDINE-CLSN---------------PCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF 1304
EG + CL N PC + G Q N C C + GR CE
Sbjct: 3448 LEGFLRSVCLENGTWTSPPICRAVCRFPCQNGG---ICQRPN--ACSCPEGWMGRLCEEP 3502
Query: 1305 VDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGP 1364
+ + +PCLNGG C + C CPPG++G+RC ++ Q C G +CV
Sbjct: 3503 ICI---LPCLNGGRCVAP------YQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRP---N 3550
Query: 1365 RCFCPS 1370
RC C S
Sbjct: 3551 RCHCLS 3556
Score = 64.3 bits (155), Expect = 1e-09
Identities = 37/103 (35%), Positives = 49/103 (47%), Gaps = 15/103 (14%)
Query: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179
CQ+ G+C + C CP G+ G CEE + PC +G C + Y+C+C PG+
Sbjct: 3476 CQNGGIC---QRPNACSCPEGWMGRLCEEPI---CILPCLNGGRC---VAPYQCDCPPGW 3526
Query: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLC 1222
G C V CQ+ PC NGG C V +C C G C
Sbjct: 3527 TGSRCHTAV--CQS-PCLNGGKC---VRPNRCHCLSSWTGHNC 3563
Score = 63.9 bits (154), Expect = 2e-09
Identities = 37/116 (31%), Positives = 51/116 (43%), Gaps = 25/116 (21%)
Query: 1069 RSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCIN 1128
R PC+N G C + A C CP GW G C+ P C + C + G C+
Sbjct: 3473 RFPCQNGGICQRPNA---CSCPEGWMGRLCEEP--ICILP-----------CLNGGRCV- 3515
Query: 1129 AGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNC 1184
+ C CP G+TGS C + +PC +G C + RC C+ + G NC
Sbjct: 3516 --APYQCDCPPGWTGSRCHTAV---CQSPCLNGGKC---VRPNRCHCLSSWTGHNC 3563
Score = 63.5 bits (153), Expect = 2e-09
Identities = 39/103 (37%), Positives = 51/103 (49%), Gaps = 14/103 (13%)
Query: 540 PCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGY 599
PC NG C PN C C G+ G LCEE I C + G+C + Y C C PG+
Sbjct: 3475 PCQNGGIC-QRPNA--CSCPEGWMGRLCEEPI--CILPCLNGGRC---VAPYQCDCPPGW 3526
Query: 600 MGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNC 642
G+ C + + SPCLN G+C V +C+C +G NC
Sbjct: 3527 TGSRCHTAVCQ---SPCLNGGKC---VRPNRCHCLSSWTGHNC 3563
Score = 61.6 bits (148), Expect = 9e-09
Identities = 38/104 (36%), Positives = 47/104 (45%), Gaps = 15/104 (14%)
Query: 919 PCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978
PCQNGG C +C C G+ G C+ + C+ PC NGG C V Y C C G
Sbjct: 3475 PCQNGGICQ---RPNACSCPEGWMGRLCEEPI--CIL-PCLNGGRC---VAPYQCDCPPG 3525
Query: 979 FDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC 1022
+ G C + +S C NGG CV C C +TG C
Sbjct: 3526 WTGSRCHTAV---CQSPCLNGGKCV---RPNRCHCLSSWTGHNC 3563
Score = 60.5 bits (145), Expect = 2e-08
Identities = 82/338 (24%), Positives = 127/338 (37%), Gaps = 68/338 (20%)
Query: 482 CMPGFKGVHCELEINE---CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSS 538
C PG+ ELE N CQ N + G + K R C P F + DI++ ++
Sbjct: 3267 CEPGY-----ELEGNRERVCQENRQWSGGVAICKETR--CETPLEFLNG--KADIENRTT 3317
Query: 539 TPCL----NGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHH----------GQC 584
P + N ++ P+ E C T + C P+PC +
Sbjct: 3318 GPNVVYSCNRGYSLEGPS--EAHCTENGTW---SHPVPLCKPNPCPVPFVIPENALLSEK 3372
Query: 585 QDGIDSYTCI-CNPGYM---GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTS-G 639
+ +D I C G++ I + DE ++ +C + G + + + G
Sbjct: 3373 EFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQ---TSAKCEKISCGPPAHVENAIARG 3429
Query: 640 VNCEINFDDCASNPCIHGICMDGINRYSCV-----CSPGFTGQRCNIDIDECASNPCRKG 694
V+ + + D + C G ++G R C+ SP C PC+ G
Sbjct: 3430 VHYQ--YGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRF--------PCQNG 3479
Query: 695 ATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINC 754
C C CPEG C + C+ PC++G ++ Y+C C GW G C
Sbjct: 3480 GIC---QRPNACSCPEGWMGRLCEEPI--CIL-PCLNGGRC--VAPYQCDCPPGWTGSRC 3531
Query: 755 EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNC 792
+PC NGG C V RC C + G+NC
Sbjct: 3532 H---TAVCQSPCLNGGKC---VRPNRCHCLSSWTGHNC 3563
Score = 58.2 bits (139), Expect = 1e-07
Identities = 37/105 (35%), Positives = 42/105 (40%), Gaps = 16/105 (15%)
Query: 309 CQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGK 368
CQNGG C N C C GW G C E I C G C VA + C CP G
Sbjct: 3476 CQNGGICQRPNA---CSCPEGWMGRLCEEPI---CILPCLNGGRC---VAPYQCDCPPGW 3526
Query: 369 AGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCT 413
G CH A +PC G C P C C + G +C+
Sbjct: 3527 TGSRCH--TAVCQSPCLNGGKC-VRPNR----CHCLSSWTGHNCS 3564
Score = 53.1 bits (126), Expect = 3e-06
Identities = 62/266 (23%), Positives = 86/266 (32%), Gaps = 75/266 (28%)
Query: 643 EINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVN 702
E D S C G + G +C +P T + + +C C A N +
Sbjct: 3373 EFYVDQNVSIKCREGFLLQGHGIITC--NPDETWTQTSA---KCEKISCGPPAHVENAI- 3426
Query: 703 GFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECL 762
G H+ Q + ++ C G G CL + W + + + C
Sbjct: 3427 ------ARGVHY-----QYGDMITYSCYSGYMLEGFLRSVCLENGTWT--SPPICRAVCR 3473
Query: 763 SNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCV 822
PCQNGG C C+C +G+ G C+ I PCLN G CV
Sbjct: 3474 F-PCQNGGICQR---PNACSCPEGWMGRLCEEPI---CILPCLNGG-----------RCV 3515
Query: 823 LPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPC 882
PY C C PGW G RC + PC
Sbjct: 3516 APYQ--------------------------------CDCPPGWTGSRCHTAV---CQSPC 3540
Query: 883 MNHGLCHNTQGSYMCECPPGFSGMDC 908
+N G C C C ++G +C
Sbjct: 3541 LNGGKCVRPN---RCHCLSSWTGHNC 3563
Score = 52.8 bits (125), Expect = 4e-06
Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Query: 33 EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCR 91
+PC N C N C C GF G +C+ + + C+ N C+N TCV + L +C+
Sbjct: 1352 QPCKNGATCKDGANSFR-CLCAAGFTGSHCELNINECQSNPCRNQATCVDE--LNSYSCK 1408
Query: 92 CASGFTGEDCQYSTS 106
C GF+G+ C+ S
Sbjct: 1409 CQPGFSGKRCETEQS 1423
Score = 47.4 bits (111), Expect = 2e-04
Identities = 57/215 (26%), Positives = 78/215 (36%), Gaps = 25/215 (11%)
Query: 859 CLCAPGWQG-QRCTIDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGFS--GMDCEEDIDD 914
C W G +D+DEC + C H C N GSY+C C P ++ G +C E I
Sbjct: 1730 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKC 1789
Query: 915 CLANPCQNGGS-----CMDGVNTFSC---LCLPGFTGDKC-QTDMNECLSEPCKNGGTCS 965
+NG S + TFSC L G T C ++ L CK
Sbjct: 1790 KAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGK 1849
Query: 966 DYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHE 1025
+ C + F C N G + G SCL ++ S + E
Sbjct: 1850 PAIPENGCIEELAF-------TFGSKVTYRC-NKGYTLAGDKESSCLANSSWSHSPPVCE 1901
Query: 1026 INECSSHPCLNEGTCV----DGLGTYRCSCPLGYT 1056
+CSS +N G + L T SC GY+
Sbjct: 1902 PVKCSSPENINNGKYILSGLTYLSTASYSCDTGYS 1936
Score = 42.4 bits (98), Expect = 0.006
Identities = 41/182 (22%), Positives = 70/182 (38%), Gaps = 34/182 (18%)
Query: 811 FDDISGYTCHCVLPYTGKNCQTVLAPCS------PNPCENAAVCKESPNFESYTCLCAPG 864
F+ ++ H LP +G Q + CS + C+ CK + + C+C G
Sbjct: 252 FEALARRALHEDLP-SGSFIQDDMVHCSYLCDEGKDCCDRMGSCKCGTHTGHFECICEKG 310
Query: 865 WQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGG 924
+ G+ + C S G+Y E PG I C+ P +N
Sbjct: 311 YYGKGLQYECTACPS-------------GTYKPEGSPG--------GISSCIPCPDENHT 349
Query: 925 SCMDGVNTFSCLCLPGFTGDKCQTDMNECLS-EPCKNG----GTCSDYVNSYT-CKCQAG 978
S + C+C G+ ++ C + +P +NG TC+++ N+ +C G
Sbjct: 350 SPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPG 409
Query: 979 FD 980
FD
Sbjct: 410 FD 411
Score = 41.6 bits (96), Expect = 0.010
Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 30/139 (21%)
Query: 1221 LCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGS-- 1278
LC+E D C R C +C G + C C G+ G+ + + C S EGS
Sbjct: 280 LCDEGKDCCDRMGSC----KCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPG 335
Query: 1279 --LDCIQL-----------TNDYLCVCRSAF--TGRHCETFVDVCPQM-PCLNG----GT 1318
CI T+ CVCR + +G+ CE + CP + P NG T
Sbjct: 336 GISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCE--LVHCPALKPPENGYFIQNT 393
Query: 1319 CAVASNMPDGFICRCPPGF 1337
C N G RC PGF
Sbjct: 394 CNNHFNAACG--VRCHPGF 410
Score = 40.4 bits (93), Expect = 0.022
Identities = 29/108 (26%), Positives = 43/108 (39%), Gaps = 8/108 (7%)
Query: 115 CLNGGTCHMLSRDTYECTCQV------GFTGKECQWTDACLSHPCANGSTCTTVANQFSC 168
CLN G +C V GF + + + +++ C NG + F C
Sbjct: 1672 CLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMF-C 1730
Query: 169 KCLTGFTGQKCET-DVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTG 215
+ G DV+EC + C +CLN+ GSY C C +TG
Sbjct: 1731 TDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG 1778
Score = 40.4 bits (93), Expect = 0.022
Identities = 43/198 (21%), Positives = 67/198 (33%), Gaps = 62/198 (31%)
Query: 911 DIDDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVN 969
D+D+C + + C SC++ ++ C C+P +TGD G C++ +
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGD----------------GKNCAEPIK 1788
Query: 970 SYTCKCQAGFDGVHCENNINECTESSCFN--GGTCVDGINSFSCLCPVGFTGSFCLHEIN 1027
CK + H I F+ G + G+ +CL H I
Sbjct: 1789 ---CKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCL-----ESGEWNHLIP 1840
Query: 1028 ECSS----HPCLNEGTCVDGLG-------TYRCSCPLGYTGKNCQTLVNLCSRSPCKNKG 1076
C + P + E C++ L TYRC NKG
Sbjct: 1841 YCKAVSCGKPAIPENGCIEELAFTFGSKVTYRC------------------------NKG 1876
Query: 1077 TCVQKKAESQCLCPSGWA 1094
+ ES CL S W+
Sbjct: 1877 YTLAGDKESSCLANSSWS 1894
Score = 39.7 bits (91), Expect = 0.037
Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 781 CTCKKGFKGYNCQ-VNIDECA-SNPCLNQGTCFDDISGYTCHCVLPYT--GKNCQTVLAP 836
CT + G + +++DECA + C +C + Y C CV PYT GKNC +
Sbjct: 1730 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKC 1789
Query: 837 CSPNPCEN 844
+P EN
Sbjct: 1790 KAPGNPEN 1797
Score = 38.5 bits (88), Expect = 0.083
Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Query: 415 DVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
DVDECA+ + C C+N DG++ C C+ Y G
Sbjct: 1745 DVDECAVGSD--CSEHASCLNVDGSYICSCVPPYTG 1778
Score = 38.1 bits (87), Expect = 0.11
Identities = 32/118 (27%), Positives = 42/118 (35%), Gaps = 26/118 (22%)
Query: 1087 CLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY----- 1141
CL W +SC + HS AG+T QC GY
Sbjct: 1672 CLNQGQWTQPLPHCERISCGVPPPLENGF------HSADDFYAGSTVTYQCNNGYYLLGD 1725
Query: 1142 TGSYCEEQ------------LDECA-SNPCQHGATCSDFIGGYRCECVPGY--QGVNC 1184
+ +C + +DECA + C A+C + G Y C CVP Y G NC
Sbjct: 1726 SRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNC 1783
Score = 37.7 bits (86), Expect = 0.14
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 267 HRCQNGGVCVDGVNTYNCRCPPQWTG--QFCTEDVDECLLQPNACQNGGTCANRNGGYGC 324
++C NG + G + C W G C DVDEC + + C +C N +G Y C
Sbjct: 1714 YQCNNGYYLL-GDSRMFCTDNGSWNGVSPSCL-DVDECAVGSD-CSEHASCLNVDGSYIC 1770
Query: 325 VCVNGWSGD--DCSENI 339
CV ++GD +C+E I
Sbjct: 1771 SCVPPYTGDGKNCAEPI 1787
Score = 37.0 bits (84), Expect = 0.24
Identities = 35/161 (21%), Positives = 53/161 (32%), Gaps = 40/161 (24%)
Query: 387 GALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLK 446
G+ + ++ Y+C +G DC + + C KC G F C C K
Sbjct: 267 GSFIQDDMVHCSYLCD-----EGKDCCDRMGSC------------KCGTHTGHFECICEK 309
Query: 447 GYAGPRCEMDINECHSD---------------PC--QNDATCLDKIGGFTCLCMPGFKGV 489
GY G + + C S PC +N + C+C G++
Sbjct: 310 GYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRAS 369
Query: 490 HCELEINECQSNPCVNNGQCVDKV--NRFQCL----CPPGF 524
E+ C + NG + N F C PGF
Sbjct: 370 GQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGF 410
Score = 36.2 bits (82), Expect = 0.41
Identities = 35/148 (23%), Positives = 59/148 (39%), Gaps = 29/148 (19%)
Query: 980 DGVHCENNINECTESSCFNGGTCVDGINS--FSCLCPVGFTGSFCLHEINECSSHPCLNE 1037
D VHC +E + C G+C G ++ F C+C G+ G +E C S
Sbjct: 273 DMVHCSYLCDE-GKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPS------ 325
Query: 1038 GTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW--AG 1095
GTY+ P G G ++ C P +N + + C+C G+ +G
Sbjct: 326 -------GTYK---PEGSPGG-----ISSCIPCPDENHTSPPGSTSPEDCVCREGYRASG 370
Query: 1096 AYCDVPNVSCD-IAASRRGVLVEHLCQH 1122
C++ V C + G +++ C +
Sbjct: 371 QTCEL--VHCPALKPPENGYFIQNTCNN 396
Score = 36.2 bits (82), Expect = 0.41
Identities = 44/183 (24%), Positives = 61/183 (33%), Gaps = 31/183 (16%)
Query: 772 CDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQ 831
C + C C+KG+ G Q C S GT Y +
Sbjct: 296 CGTHTGHFECICEKGYYGKGLQYECTACPS------GT---------------YKPEGSP 334
Query: 832 TVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS-KPCMNHGLCHN 890
++ C P P EN S + E C+C G++ T ++ C + KP N N
Sbjct: 335 GGISSCIPCPDENHTSPPGSTSPED--CVCREGYRASGQTCELVHCPALKPPENGYFIQN 392
Query: 891 TQGSYM-----CECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDK 945
T ++ C PGF + I CL N +G V T L P
Sbjct: 393 TCNNHFNAACGVRCHPGFDLVG--SSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHIS 450
Query: 946 CQT 948
C T
Sbjct: 451 CST 453
Score = 36.2 bits (82), Expect = 0.41
Identities = 12/35 (34%), Positives = 20/35 (57%)
Query: 1225 NIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGE 1259
++D+CA G C C++ G Y C C+P + G+
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGD 1779
Score = 35.4 bits (80), Expect = 0.70
Identities = 59/243 (24%), Positives = 84/243 (34%), Gaps = 59/243 (24%)
Query: 61 YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYS-TSHPCFVSRP----- 114
+C + K+ C G+C G C C G+ G+ QY T+ P +P
Sbjct: 276 HCSYLCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPG 335
Query: 115 ----CL----NGGTCHMLSRDTYECTCQVGF--TGKECQWTDACLSHPCANG----STCT 160
C+ T S +C C+ G+ +G+ C+ P NG +TC
Sbjct: 336 GISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCN 395
Query: 161 TVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-PQGF---TGQ 216
N F+ C G +C PG +L GS C P G +
Sbjct: 396 ---NHFNAAC-----GVRCH--------PG--------FDLVGSSIILCLPNGLWSGSES 431
Query: 217 YCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPG------FEGS---TCERNID-DCPN 266
YC P P +G T + ++ CL EGS TC+ N D P
Sbjct: 432 YCRVRTCPHLRQP-KHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPE 490
Query: 267 HRC 269
RC
Sbjct: 491 PRC 493
Score = 35.0 bits (79), Expect = 0.92
Identities = 44/176 (25%), Positives = 60/176 (34%), Gaps = 41/176 (23%)
Query: 331 SGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALC 390
SG +++ C++ C G C DR+ S C G H + C KG
Sbjct: 266 SGSFIQDDMVHCSYL-CDEGKDCCDRMGSCKCGTHTG------HFECICEKGYYGKGL-- 316
Query: 391 DTNPLNGQYICT-CPQG-YKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY 448
QY CT CP G YK + C P E+ + C C +GY
Sbjct: 317 -------QYECTACPSGTYKPEGSPGGISSCIPC---PDENHTSPPGSTSPEDCVCREGY 366
Query: 449 --AGPRCEMDINECHSDP---------CQN--DATC-------LDKIGGFTCLCMP 484
+G CE+ P C N +A C D +G LC+P
Sbjct: 367 RASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLP 422
Score = 35.0 bits (79), Expect = 0.92
Identities = 43/180 (23%), Positives = 64/180 (35%), Gaps = 27/180 (15%)
Query: 505 NNGQCVDKVNRFQCLCPPGFTG--PVCQIDIDDCS-STPCLNGAKCIDHPNGYECQCATG 561
NNG + +R C + G P C +D+D+C+ + C A C++ Y C C
Sbjct: 1717 NNGYYLLGDSRMFCTDNGSWNGVSPSC-LDVDECAVGSDCSEHASCLNVDGSYICSCVPP 1775
Query: 562 FT--GVLCEENIDNCDPDPCHHGQCQDGI----DSYTCICNPGYMGAICSDQIDECYSSP 615
+T G C E I P +G I T C GY Q+
Sbjct: 1776 YTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGY-------QLMGVTKIT 1828
Query: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFT 675
CL G L+ P V+C N CI + ++ + C+ G+T
Sbjct: 1829 CLESGEWNHLI--------PYCKAVSC--GKPAIPENGCIEELAFTFGSKVTYRCNKGYT 1878
Score = 33.5 bits (75), Expect = 2.7
Identities = 22/90 (24%), Positives = 37/90 (41%), Gaps = 15/90 (16%)
Query: 1142 TGSYCEEQLDECASNPCQHGATCSDFIGG---------YRCECVPGYQGVNCEYEVDECQ 1192
+GS+ ++ + C S C G C D +G + C C GY G +YE C
Sbjct: 266 SGSFIQDDMVHC-SYLCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACP 324
Query: 1193 NQPCQNGGTCIDLVNHFKC-----SCPPGT 1217
+ + G+ + + C + PPG+
Sbjct: 325 SGTYKPEGSPGGISSCIPCPDENHTSPPGS 354
Score = 33.1 bits (74), Expect = 3.5
Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Query: 451 PRCEMDINECH-SDPCQNDATCLDKIGGFTCLCMPGFKG 488
P C +D++EC C A+CL+ G + C C+P + G
Sbjct: 1741 PSC-LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG 1778
Score = 33.1 bits (74), Expect = 3.5
Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 4/76 (5%)
Query: 375 LDDACISNPCHKGALCDTNPLNGQYICTCPQGY--KGADCTEDVDECAMANSNPCEHAGK 432
+D+ + + C + A C ++G YIC+C Y G +C E + A N +G+
Sbjct: 1746 VDECAVGSDCSEHASCLN--VDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGE 1803
Query: 433 CVNTDGAFHCECLKGY 448
C +GY
Sbjct: 1804 IYTVGAEVTFSCQEGY 1819
Score = 32.3 bits (72), Expect = 5.9
Identities = 47/191 (24%), Positives = 59/191 (30%), Gaps = 46/191 (24%)
Query: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGF-----TGPVCQIDIDDCSSTPCLNGAKCI 548
E+N+ S P + + F+ L +G Q D+ CS C G C
Sbjct: 230 ELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHCSYL-CDEGKDCC 288
Query: 549 D---------HPNGYECQCATGFTG-------VLCEE----------NIDNCDPDPCHHG 582
D H +EC C G+ G C I +C P P +
Sbjct: 289 DRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENH 348
Query: 583 QCQDGIDS-YTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGY--QCNCQ---PG 636
G S C+C GY S Q E P L NGY Q C
Sbjct: 349 TSPPGSTSPEDCVCREGYR---ASGQTCELVHCPALKPPE-----NGYFIQNTCNNHFNA 400
Query: 637 TSGVNCEINFD 647
GV C FD
Sbjct: 401 ACGVRCHPGFD 411
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 261 bits (667), Expect = 6e-69
Identities = 272/1038 (26%), Positives = 389/1038 (37%), Gaps = 265/1038 (25%)
Query: 119 GTCHMLSRDTYECTCQVGF----TGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGF 174
GTC L D Y C C G+ + C + CL PC C +SC C G+
Sbjct: 859 GTCVNLP-DGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGY 917
Query: 175 T------GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPS 228
T Q+C+ D+NEC+ PG C GG C N GSY C+C QG Y+
Sbjct: 918 TLATSGATQECQ-DINECEQPGVCS-GGQCTNTEGSYHCECDQG---------YIMVRKG 966
Query: 229 PCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNC-RCP 287
C + CR G CP+ G CV+ +Y C C
Sbjct: 967 HCQDINECRHPG----------------------TCPD------GRCVNSPGSYTCLACE 998
Query: 288 PQWTGQF-CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW---SGDDCSENIDDCA 343
+ GQ DV+EC L P C + G C N G + C C G+ S + +++D+CA
Sbjct: 999 EGYRGQSGSCVDVNEC-LTPGVCAH-GKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECA 1056
Query: 344 FASCTPGSTCIDRVASFSC-MCPEG----KAGLLCH-LDDACISNPCHKGALCDTNPLNG 397
+ P C++ SF+C C G + G C LD+ C G +T G
Sbjct: 1057 SRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNT---AG 1113
Query: 398 QYIC-TCPQGYKGA---DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA---G 450
+ C C GY+ + D EDVDEC S+ G+C NT G++ C C +G+ G
Sbjct: 1114 SFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCL--GGECKNTVGSYQCLCPQGFQLANG 1171
Query: 451 PRCEMDINECHSDP-CQNDATCLDKIGGFTCLCMPGF----KGVHCELEINEC-QSNPCV 504
CE D+NEC + C CL+ G F CLC PGF G C+ +++EC ++PCV
Sbjct: 1172 TVCE-DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQ-DVDECATTDPCV 1229
Query: 505 NNGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCS--STPCLNGAKCIDHPNGYEC-- 556
G CV+ F CLC GF C +DID+C P KC + P Y C
Sbjct: 1230 -GGHCVNTEGSFNCLCETGFQPSPESGEC-VDIDECEDYGDPVCGTWKCENSPGSYRCVL 1287
Query: 557 QCATGFTGVLCEENIDNCDPDPC-------HHGQCQDGIDSYTCICNPGY---------- 599
C GF N D D D C HG C + S+ C+C+ G+
Sbjct: 1288 GCQPGFH---MAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCV 1344
Query: 600 -----------MGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFD- 647
GA + ++ + C +D D G+ C+P +G
Sbjct: 1345 DVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGH---CRPRGAGGQSMSEAPT 1401
Query: 648 ----------DCASNPCIHGICMDGINRYS----CVCSPGFT-GQRCNIDIDECASNPCR 692
DC S H C + R + C C+ G + G C D C S
Sbjct: 1402 GDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDAC----DLCPSEDSA 1457
Query: 693 KGATCINGVNGFRCICPEGPHH----------PSCYSQVNECL---SNPCIHGNCTGGLS 739
+ F ICP G + + Y+ +EC+ C +G C +
Sbjct: 1458 E----------FSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVP 1507
Query: 740 GYKCLCDAGW----VGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVN 795
GY CLC+ G+ CE D +EC C+N G C N + C C +
Sbjct: 1508 GYVCLCNPGFHYDASHKKCE-DHDECQDLACEN-GECVNTEGSFHCFCSP-------PLT 1558
Query: 796 IDECASNPCLNQGTCFDDISGYTCH------------CVLPYTGKNCQTVLAPCSPNPC- 842
+D + C+N + +D+ + H C P G C
Sbjct: 1559 LD-LSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAW 1617
Query: 843 -ENAAVCKESPNFESYTCLC---------------APGWQGQRCTIDI------------ 874
+ A+C + E Y LC PG++ D+
Sbjct: 1618 SQQCALCPPRSS-EVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYSIYGPDGAPF 1676
Query: 875 ------DECISKPCMNHGLCHNTQGSYMCECP------------------PGFSGMDCEE 910
++ + +P + H+ + + E P GF G+ EE
Sbjct: 1677 YNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVASHPEPPAGFEGLQAEE 1736
Query: 911 DIDDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQ---TDMNEC--LSEP---CKNG 961
C + N C+N G C+ ++C C GF D D+NEC L+ P C +
Sbjct: 1737 ----CGILNGCEN-GRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH- 1790
Query: 962 GTCSDYVNSYTCKCQAGF 979
G C + SY C C G+
Sbjct: 1791 GYCENTEGSYRCHCSPGY 1808
Score = 251 bits (640), Expect = 8e-66
Identities = 276/1037 (26%), Positives = 390/1037 (37%), Gaps = 209/1037 (20%)
Query: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEM---DINECHSDPCQNDA 469
T +D CA +N C G CVN + C C GY + D NEC DPC+
Sbjct: 842 TPGIDRCAAGATNVCG-PGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKG 900
Query: 470 TCLDKIGGFTCLCMPGF----KGVHCEL-EINECQSNPCVNNGQCVDKVNRFQCLCPPGF 524
C++++G ++C C PG+ G E +INEC+ + GQC + + C C G+
Sbjct: 901 RCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGY 960
Query: 525 ---TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYEC-QCATGFTGV--LCEENIDNCDPDP 578
CQ DI++C +C++ P Y C C G+ G C + + P
Sbjct: 961 IMVRKGHCQ-DINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGV 1019
Query: 579 CHHGQCQDGIDSYTCICNPGYMGAICSDQ-----IDECYSSPCLNDGRCIDLVNGYQCN- 632
C HG+C + S+ C C GY + SD+ +DEC S G C++ + C+
Sbjct: 1020 CAHGKCTNLEGSFRCSCEQGY--EVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSA 1077
Query: 633 CQPG----TSGVNCEINFDDCA-SNPCIHGICMDGINRYSCV-CSPGF----TGQRCNID 682
C+ G G CE + D+CA C G+C + +SC C G+ G C D
Sbjct: 1078 CENGYWVNEDGTACE-DLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE-D 1135
Query: 683 IDEC--ASNPCRKGATCINGVNGFRCICPEGPH--HPSCYSQVNECLSNP--CIHGNCTG 736
+DEC + C G C N V ++C+CP+G + + VNEC+ HG C
Sbjct: 1136 VDECEDPQSSC-LGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLN 1194
Query: 737 GLSGYKCLCDAGWV----GINCEVDKNEC-LSNPCQNGGTCDNLVNGYRCTCKKGFKGYN 791
+ CLC G+V G +C+ D +EC ++PC GG C N + C C+ GF+
Sbjct: 1195 SHGSFFCLCAPGFVSAEGGTSCQ-DVDECATTDPCV-GGHCVNTEGSFNCLCETGFQ--- 1249
Query: 792 CQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAP-CSPNPCENAAVCKE 850
P G C D C+ P C CEN
Sbjct: 1250 -----------PSPESGECVDI--------------DECEDYGDPVCGTWKCEN------ 1278
Query: 851 SPNFESYTCL--CAPGWQ--GQRCTIDIDECISKP-CMNHGLCHNTQGSYMCECPPGF-- 903
SP SY C+ C PG+ IDIDEC + C +HG C NT GS+ C C GF
Sbjct: 1279 SPG--SYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEI 1336
Query: 904 --SGMDCEEDIDDCLANPCQNGGSCMDGV-NTFSCLCLPGFTGDKCQTDMNECLSEPCKN 960
SG DC D+++C G + + V +F CLC D + D E P
Sbjct: 1337 SPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLC----ASDLEEYDAQEGHCRPRGA 1391
Query: 961 GG------TCSDYVNSYT-CKCQAGFDG-VHCENNINECT---ESSCFNGGTCVDGIN-- 1007
GG D+ + T C +G G C + + T E C G + D +
Sbjct: 1392 GGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLC 1451
Query: 1008 ------SFSCLCPVG-----FTGSFCLHEINECSSHPCL-------NEGTCVDGLGTYRC 1049
FS +CP G G++ + + C+ G C++ + Y C
Sbjct: 1452 PSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVC 1511
Query: 1050 SCPLGY----TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC 1105
C G+ + K C+ + C C+N G CV + C C D+ C
Sbjct: 1512 LCNPGFHYDASHKKCED-HDECQDLACEN-GECVNTEGSFHCFCSPPLT---LDLSQQRC 1566
Query: 1106 DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPL-----GYTGSYC---EEQLDECASNP 1157
+ S L +H H +C C PL YT C E +CA P
Sbjct: 1567 MNSTSSTEDLPDHDI-HMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCP 1625
Query: 1158 CQHGATCSDFIGGYRCECV--------PGYQ----GVNCEYEVDECQNQPCQN------- 1198
+ + R E PGY+ + Y + P N
Sbjct: 1626 PRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYSIYGPDGAPFYNYLGPEDT 1685
Query: 1199 ---------GGTCID-------------LVNHFKCS---CPPGTRGLLCEENIDDCARGP 1233
G D L H+ S P G GL EE C
Sbjct: 1686 VPEPAFPNTAGHSADRTPILESPLQPSELQPHYVASHPEPPAGFEGLQAEE----CGILN 1741
Query: 1234 HCLNGGQCMDRIGGYSCRCLPGF---AGERCEGDINEC--LSNPCSSEGSLDCIQLTNDY 1288
C N G+C+ GY+C C GF A D+NEC L+ P C Y
Sbjct: 1742 GCEN-GRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSY 1800
Query: 1289 LCVCRSAFTGR----HC 1301
C C + HC
Sbjct: 1801 RCHCSPGYVAEAGPPHC 1817
Score = 250 bits (639), Expect = 1e-65
Identities = 214/741 (28%), Positives = 320/741 (43%), Gaps = 108/741 (14%)
Query: 296 TEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW----SGDDCSENIDDCAFASCTPGS 351
T +D C GTC N GY CVC G+ S C+++ ++C C
Sbjct: 842 TPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDD-NECLRDPCKGKG 900
Query: 352 TCIDRVASFSCMCPEGKAGLLCHLDDACIS-NPCHKGALCD----TNPLNGQYICTCPQG 406
CI+RV S+SC C G C N C + +C TN G Y C C QG
Sbjct: 901 RCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTN-TEGSYHCECDQG 959
Query: 407 Y---KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHC-ECLKGYAGPRCE-MDINECH 461
Y + C +D++EC + P G+CVN+ G++ C C +GY G +D+NEC
Sbjct: 960 YIMVRKGHC-QDINECRHPGTCP---DGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECL 1015
Query: 462 SDPCQNDATCLDKIGGFTCLCMPGFKGVHCE---LEINECQSNPCVNNGQCVDKVNRFQC 518
+ C + G F C C G++ E +++EC S G C++ F C
Sbjct: 1016 TPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFAC 1075
Query: 519 -LCPPGF----TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQ-CATGF----TGVLCE 568
C G+ G C+ D+D+C+ C + + C+ C G+ G CE
Sbjct: 1076 SACENGYWVNEDGTACE-DLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE 1134
Query: 569 ENIDNCDPDP---CHHGQCQDGIDSYTCICNPGYM---GAICSDQIDECYSSP-CLNDGR 621
+ +D C+ DP C G+C++ + SY C+C G+ G +C D ++EC C G
Sbjct: 1135 D-VDECE-DPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCED-VNECMGEEHCAPHGE 1191
Query: 622 CIDLVNGYQCNCQPG----TSGVNCEINFDDCA-SNPCIHGICMDGINRYSCVCSPGF-- 674
C++ + C C PG G +C+ + D+CA ++PC+ G C++ ++C+C GF
Sbjct: 1192 CLNSHGSFFCLCAPGFVSAEGGTSCQ-DVDECATTDPCVGGHCVNTEGSFNCLCETGFQP 1250
Query: 675 --TGQRCNIDIDECA--SNPCRKGATCINGVNGFRCI--CPEGPH---HPSCYSQVNECL 725
C +DIDEC +P C N +RC+ C G H + C ++EC
Sbjct: 1251 SPESGEC-VDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCI-DIDECA 1308
Query: 726 SNPCI--HGNCTGGLSGYKCLCDAGW----VGINCEVDKNEC-LSNPCQNGGTCDNLVNG 778
++ HG C ++CLCD G+ G +C VD NEC L C+N+
Sbjct: 1309 NDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDC-VDVNECELMLAVCGAALCENVEGS 1367
Query: 779 YRCTCKKGFKGYNCQ-----------VNIDECASN---PCLNQGTCFDDISGYT-CHCVL 823
+ C C + Y+ Q ++ E + P + C+ G+ C VL
Sbjct: 1368 FLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVL 1427
Query: 824 PYTGKN------CQTVLA----PCSPNPCENAAVCKE-SPNFESYTCLCAPGWQGQRCTI 872
G+N C T A C P E++A E P+ + Y + GQ
Sbjct: 1428 ---GRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYT 1484
Query: 873 DIDECI--SKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEEDIDDCLANPCQNGGSC 926
D DEC+ +G C NT Y+C C PGF S C ED D+C C+N G C
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKC-EDHDECQDLACEN-GEC 1542
Query: 927 MDGVNTFSCLCLPGFTGDKCQ 947
++ +F C C P T D Q
Sbjct: 1543 VNTEGSFHCFCSPPLTLDLSQ 1563
Score = 237 bits (605), Expect = 9e-62
Identities = 269/1054 (25%), Positives = 416/1054 (39%), Gaps = 225/1054 (21%)
Query: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFL----GEYCQHRDPCEKNRCQNGGTCVAQ 82
+C G G CV +G C C G+ YC + C ++ C+ G C+ +
Sbjct: 847 RCAAGATNVCGPGTCVNLPDGYR-CVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINR 905
Query: 83 AMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC 142
+G +C C G+T +TS G T +EC
Sbjct: 906 --VGSYSCFCYPGYT-----LATS-----------GAT-------------------QEC 928
Query: 143 QWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQK---CETDVNECDIPGHCQHGGTCL 199
Q + C +G CT + C+C G+ + C+ D+NEC PG C G C+
Sbjct: 929 QDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQ-DINECRHPGTCP-DGRCV 986
Query: 200 NLPGSYQC-QCPQGFTGQ--YCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGST 256
N PGSY C C +G+ GQ C + P C +G G +F C+C G+E ++
Sbjct: 987 NSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEG--SFRCSCEQGYEVTS 1044
Query: 257 CER---NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQ--WTGQFCT--EDVDECLLQPNAC 309
E+ ++D+C + G+C++ ++ C W + T ED+DEC P C
Sbjct: 1045 DEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVC 1103
Query: 310 QNGGTCANRNGGYGCV-CVNGWS----GDDCSENIDDC--AFASCTPGSTCIDRVASFSC 362
+ G C N G + C C G+ GD C E++D+C +SC G C + V S+ C
Sbjct: 1104 PS-GVCTNTAGSFSCKDCDGGYRPSPLGDSC-EDVDECEDPQSSCL-GGECKNTVGSYQC 1160
Query: 363 MCPEG---KAGLLCHLDDACISNP-CHKGALCDTNPLNGQYICTCPQGY---KGADCTED 415
+CP+G G +C + C+ C C + +G + C C G+ +G +D
Sbjct: 1161 LCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNS--HGSFFCLCAPGFVSAEGGTSCQD 1218
Query: 416 VDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE----MDINEC--HSDPCQNDA 469
VDEC A ++PC G CVNT+G+F+C C G+ P E +DI+EC + DP
Sbjct: 1219 VDEC--ATTDPCV-GGHCVNTEGSFNCLCETGFQ-PSPESGECVDIDECEDYGDPVCGTW 1274
Query: 470 TCLDKIGGFTCL--CMPGF---KGVHCELEINECQSNP-CVNNGQCVDKVNRFQCLCPPG 523
C + G + C+ C PGF C ++I+EC ++ C ++G C + F+CLC G
Sbjct: 1275 KCENSPGSYRCVLGCQPGFHMAPNGDC-IDIDECANDTMCGSHGFCDNTDGSFRCLCDQG 1333
Query: 524 F----TGPVCQIDIDDCSSTPCLNGAKCIDHPNG-YECQCATGFTGVLCEENIDNCDPD- 577
F +G C +D+++C + GA ++ G + C CA+ +E +C P
Sbjct: 1334 FEISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEG--HCRPRG 1390
Query: 578 ---------------------PCHHGQ-----CQDGIDSYT----CICNPGYMGAICSDQ 607
C+ GQ C + T C C GA D
Sbjct: 1391 AGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCT---QGASWGDA 1447
Query: 608 IDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDC---ASNPCIHGICMDGIN 664
D C S GY T G + D+C C +G C++ +
Sbjct: 1448 CDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVP 1507
Query: 665 RYSCVCSPGF----TGQRCNIDIDECASNPCRKGATCINGVNGFRCIC------------ 708
Y C+C+PGF + ++C D DEC C G C+N F C C
Sbjct: 1508 GYVCLCNPGFHYDASHKKCE-DHDECQDLACENG-ECVNTEGSFHCFCSPPLTLDLSQQR 1565
Query: 709 ------------PEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEV 756
H C+ +V + + + G+ T + +C C G E
Sbjct: 1566 CMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRT---TYTECCCQDG------EA 1616
Query: 757 DKNECLSNPCQNGGTCDNLVNGYRCTCKKGF-----KGYNCQVNIDECASNPCLNQGTCF 811
+C P ++ L N R ++ GY D+ + G F
Sbjct: 1617 WSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYSIYGPDGAPF 1676
Query: 812 DDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAA---VCKESP----NFESYTCLCAP- 863
+ Y G TV P PN ++A ESP + + P
Sbjct: 1677 YN-----------YLGPE-DTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVASHPE 1724
Query: 864 ---GWQGQRCTIDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGF----SGMDCEEDIDDC 915
G++G + +EC I C N G C + Y C+C GF + M C D+++C
Sbjct: 1725 PPAGFEG----LQAEECGILNGCEN-GRCVRVREGYTCDCFEGFQLDAAHMAC-VDVNEC 1778
Query: 916 --LANP---CQNGGSCMDGVNTFSCLCLPGFTGD 944
L P C + G C + ++ C C PG+ +
Sbjct: 1779 DDLNGPAVLCVH-GYCENTEGSYRCHCSPGYVAE 1811
Score = 229 bits (583), Expect = 3e-59
Identities = 209/744 (28%), Positives = 317/744 (42%), Gaps = 138/744 (18%)
Query: 726 SNPCIHGNCTGGLSGYKCLCDAGWVGINCEV---DKNECLSNPCQNGGTCDNLVNGYRCT 782
+N C G C GY+C+C G+ + D NECL +PC+ G C N V Y C
Sbjct: 853 TNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCF 912
Query: 783 CKKGFK------GYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYT---GKNCQTV 833
C G+ CQ +I+EC + G C + Y C C Y +CQ +
Sbjct: 913 CYPGYTLATSGATQECQ-DINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDI 971
Query: 834 LAPCSPNPCENAAVCKESPNFESYTCL-CAPGWQGQRCT-IDIDECISKPCMNHGLCHNT 891
P C + C SP SYTCL C G++GQ + +D++EC++ HG C N
Sbjct: 972 NECRHPGTCPDGR-CVNSPG--SYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNL 1028
Query: 892 QGSYMCECPPGFSGMDCE---EDIDDCLANPCQNGGSCMDGVNTFSC-LCLPGF----TG 943
+GS+ C C G+ E +D+D+C + G C++ +F+C C G+ G
Sbjct: 1029 EGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDG 1088
Query: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYTCK-CQAGFD----GVHCENNINECTE--SSC 996
C+ D++EC G C++ S++CK C G+ G CE+ ++EC + SSC
Sbjct: 1089 TACE-DLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCED-VDECEDPQSSC 1146
Query: 997 FNGGTCVDGINSFSCLCPVGF---TGSFCLHEINECSSHP-CLNEGTCVDGLGTYRCSCP 1052
GG C + + S+ CLCP GF G+ C ++NEC C G C++ G++ C C
Sbjct: 1147 L-GGECKNTVGSYQCLCPQGFQLANGTVC-EDVNECMGEEHCAPHGECLNSHGSFFCLCA 1204
Query: 1053 LGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLC-----PSGWAGAYCDVPNV 1103
G+ G +CQ + + PC G CV + CLC PS +G D+
Sbjct: 1205 PGFVSAEGGTSCQDVDECATTDPCVG-GHCVNTEGSFNCLCETGFQPSPESGECVDIDE- 1262
Query: 1104 SCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQ--CPLGY---TGSYCEEQLDECASNP- 1157
C+ + +C + C N+ ++ C C G+ C + +DECA++
Sbjct: 1263 -CEDYG-------DPVCG-TWKCENSPGSYRCVLGCQPGFHMAPNGDCID-IDECANDTM 1312
Query: 1158 CQHGATCSDFIGGYRCECVPGYQ----GVNCEYEVDECQNQPCQNGGT-CIDLVNHFKCS 1212
C C + G +RC C G++ G +C +V+EC+ G C ++ F C
Sbjct: 1313 CGSHGFCDNTDGSFRCLCDQGFEISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCL 1371
Query: 1213 C---------------PPGTRGL-LCEENIDDCARGP---HCLNGGQ----CMDRIGGYS 1249
C P G G + E D A P C +G + C +G +
Sbjct: 1372 CASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNT 1431
Query: 1250 ----CRCLPGFA-GERCEGDINECLSNPCSSEGSLDCIQLT---NDYLCVCRSAFTGRHC 1301
C C G + G+ C+ C SE S + ++ Y+ V + G+
Sbjct: 1432 TQAECCCTQGASWGDACD---------LCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTM 1482
Query: 1302 ETFVD--------VCPQMPCLNGGTCAVASNMPDGFICRCPPGF----SGARCQS--SCG 1347
T D +CP CLN +P G++C C PGF S +C+ C
Sbjct: 1483 YTDADECVIFGPGLCPNGRCLN--------TVP-GYVCLCNPGFHYDASHKKCEDHDECQ 1533
Query: 1348 QVKCRKGEQCVHTASGPRCFCPSP 1371
+ C GE CV+T CFC P
Sbjct: 1534 DLACENGE-CVNTEGSFHCFCSPP 1556
Score = 206 bits (524), Expect = 2e-52
Identities = 266/1040 (25%), Positives = 389/1040 (37%), Gaps = 175/1040 (16%)
Query: 578 PCHHGQCQDGIDSYTCICNPGYMG---AICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQ 634
PC I++ C GY C D I+EC + D C++ Y C C+
Sbjct: 591 PCPPRPASPVIENGQLECPQGYKRLNLTHCQD-INECLTLGLCKDAECVNTRGSYLCTCR 649
Query: 635 PGTSGVNCEINFDDCASNPCI---HGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPC 691
P G+ + + C S+ I G+C + +C QR I C+
Sbjct: 650 P---GLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLP---LAQRITKQICCCSRVGK 703
Query: 692 RKGATC----INGVNGFRCICPEGPHHPSCYSQV---------NECLSNPCIHG-NCTGG 737
G+ C + G FR ICP G + S + E P G +G
Sbjct: 704 AWGSECEKCPLPGTEAFREICPAGHGYTYASSDIRLSMRKAEEEELARPPREQGQRSSGA 763
Query: 738 LSG------YKCLCDAGWVGINCEVDKNECLSNPCQNGGT-CDNLVNGYRCTCKKGFKGY 790
L G + + D W+ DK + + T V G T +G
Sbjct: 764 LPGPAERQPLRVVTDT-WLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATTPPMPEQGI 822
Query: 791 N-----------------CQVNIDEC---ASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
ID C A+N C GTC + GY C C Y
Sbjct: 823 AEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVC-GPGTCVNLPDGYRCVCSPGYQLHPS 881
Query: 831 QTVLA---PCSPNPCENAAVCKESPNFESYTCLCAPGW------QGQRCTIDIDECISKP 881
Q C +PC+ C SY+C C PG+ Q C DI+EC
Sbjct: 882 QAYCTDDNECLRDPCKGKGRCIN--RVGSYSCFCYPGYTLATSGATQECQ-DINECEQPG 938
Query: 882 CMNHGLCHNTQGSYMCECPPGFSGM---DCEEDIDDCLANPCQNGGSCMDGVNTFSCL-C 937
+ G C NT+GSY CEC G+ + C +DI++C G C++ +++CL C
Sbjct: 939 VCSGGQCTNTEGSYHCECDQGYIMVRKGHC-QDINECRHPGTCPDGRCVNSPGSYTCLAC 997
Query: 938 LPGFTGDKCQ-TDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCE---NNINECTE 993
G+ G D+NECL+ G C++ S+ C C+ G++ E +++EC
Sbjct: 998 EEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECAS 1057
Query: 994 SSCFNGGTCVDGINSFSC-LCPVGF----TGSFCLHEINECSSHPCLNEGTCVDGLGTYR 1048
+ G C++ SF+C C G+ G+ C +++EC+ G C + G++
Sbjct: 1058 RASCPTGLCLNTEGSFACSACENGYWVNEDGTAC-EDLDECAFPGVCPSGVCTNTAGSFS 1116
Query: 1049 C-SCPLGY----TGKNCQTLVNLCS--RSPCKNKGTCVQKKAESQCLCPSGWA---GAYC 1098
C C GY G +C+ V+ C +S C G C QCLCP G+ G C
Sbjct: 1117 CKDCDGGYRPSPLGDSCED-VDECEDPQSSCLG-GECKNTVGSYQCLCPQGFQLANGTVC 1174
Query: 1099 DVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT----GSYCEEQLDECA 1154
+ N C + E C G C+N+ + +C C G+ G+ C++ +DECA
Sbjct: 1175 EDVN-EC---------MGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQD-VDECA 1223
Query: 1155 -SNPCQHGATCSDFIGGYRCECVPGYQ----GVNCEYEVDECQN--QPCQNGGTCIDLVN 1207
++PC G C + G + C C G+Q C ++DEC++ P C +
Sbjct: 1224 TTDPCV-GGHCVNTEGSFNCLCETGFQPSPESGEC-VDIDECEDYGDPVCGTWKCENSPG 1281
Query: 1208 HFKC--SCPPGTRGLLCEE--NIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF----AGE 1259
++C C PG + +ID+CA C + G C + G + C C GF +G
Sbjct: 1282 SYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGW 1341
Query: 1260 RCEGDINEC--LSNPCSSEGSLDCIQLTNDYLCVCRSAF-----TGRHCETFVDVCPQMP 1312
C D+NEC + C G+ C + +LC+C S HC
Sbjct: 1342 DCV-DVNECELMLAVC---GAALCENVEGSFLCLCASDLEEYDAQEGHCRP--------- 1388
Query: 1313 CLNGGTCAVASNMPDGFICRCPPG---FSGARCQSSCGQVKCRKGEQ----CVHTAS-GP 1364
G S P G P +SG + + C V R Q C AS G
Sbjct: 1389 --RGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGD 1446
Query: 1365 RC-FCPSPRDCESGCASSPCQHGGSCHPQR------QPPYYSCQCAPPFSGSRCELYTAP 1417
C CPS E S C G P Q Y F C
Sbjct: 1447 ACDLCPSEDSAE---FSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCL 1503
Query: 1418 PSTPPATCLS----QYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCW 1473
+ P CL Y A + DE C AC + G+C T + CS PL
Sbjct: 1504 NTVPGYVCLCNPGFHYDASHKKCEDHDE-CQDLAC--ENGECVNTEGSFHCFCSPPLTL- 1559
Query: 1474 DYINNQCDELCNTVECLFDN 1493
D +C ++ E L D+
Sbjct: 1560 DLSQQRCMNSTSSTEDLPDH 1579
Score = 196 bits (498), Expect = 2e-49
Identities = 202/728 (27%), Positives = 285/728 (39%), Gaps = 142/728 (19%)
Query: 912 IDDCLA---NPCQNGGSCMDGVNTFSCLCLPGFTGDKCQ---TDMNECLSEPCKNGGTCS 965
ID C A N C G+C++ + + C+C PG+ Q TD NECL +PCK G C
Sbjct: 845 IDRCAAGATNVC-GPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCI 903
Query: 966 DYVNSYTCKCQAGF----DGVHCE-NNINECTESSCFNGGTCVDGINSFSCLCPVGF--- 1017
+ V SY+C C G+ G E +INEC + +GG C + S+ C C G+
Sbjct: 904 NRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMV 963
Query: 1018 TGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLGYTGKNCQTL-VNLCSRSPCKNK 1075
C +INEC +G CV+ G+Y C +C GY G++ + VN C
Sbjct: 964 RKGHC-QDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAH 1022
Query: 1076 GTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYC 1135
G C + +C C G+ + D ASR +G+C+N + C
Sbjct: 1023 GKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASC-------PTGLCLNTEGSFAC 1075
Query: 1136 Q-CPLGY----TGSYCEEQLDECASNPCQHGATCSDFIGGYRC-ECVPGYQ----GVNCE 1185
C GY G+ CE+ LDECA C++ G + C +C GY+ G +CE
Sbjct: 1076 SACENGYWVNEDGTACED-LDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE 1134
Query: 1186 YEVDECQN-QPCQNGGTCIDLVNHFKCSCPPG---TRGLLCEENIDDCARGPHCLNGGQC 1241
+VDEC++ Q GG C + V ++C CP G G +CE+ +++C HC G+C
Sbjct: 1135 -DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCED-VNECMGEEHCAPHGEC 1192
Query: 1242 MDRIGGYSCRCLPGF----AGERCEGDINEC-LSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296
++ G + C C PGF G C+ D++EC ++PC C+ + C+C + F
Sbjct: 1193 LNSHGSFFCLCAPGFVSAEGGTSCQ-DVDECATTDPCVGG---HCVNTEGSFNCLCETGF 1248
Query: 1297 TGR----------HCETFVD-VCPQMPCLNGGTCAVASNMPDGFIC--RCPPGFSGA--- 1340
CE + D VC C N P + C C PGF A
Sbjct: 1249 QPSPESGECVDIDECEDYGDPVCGTWKC---------ENSPGSYRCVLGCQPGFHMAPNG 1299
Query: 1341 ---RCQSSCGQVKCRKGEQCVHTASGPRCFC-------PSPRDCE---------SGCASS 1381
C C +T RC C PS DC + C ++
Sbjct: 1300 DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAA 1359
Query: 1382 PCQH-GGS--CHPQRQPPYYSCQ---CAPPFSGSRCELYTAPPS--TPPATCLSQYCADK 1433
C++ GS C Y Q C P +G + + AP P T + Y K
Sbjct: 1360 LCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQ-SMSEAPTGDHAPAPTRMDCYSGQK 1418
Query: 1434 ---------ARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLP----------CWD 1474
R+ E C + W G C L A S P W
Sbjct: 1419 GHAPCSSVLGRNTTQAECCCTQGASW-GDACDLCPSEDSAEFSEICPSGKGYIPVEGAWT 1477
Query: 1475 Y---INNQCDE-------LCNTVECL--FDNFECQGNSKTCKYD---KYCADHFKDNHCD 1519
+ + DE LC CL + C N YD K C DH D D
Sbjct: 1478 FGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCN-PGFHYDASHKKCEDH--DECQD 1534
Query: 1520 QGCNSEEC 1527
C + EC
Sbjct: 1535 LACENGEC 1542
Score = 162 bits (409), Expect = 5e-39
Identities = 227/912 (24%), Positives = 331/912 (36%), Gaps = 190/912 (20%)
Query: 694 GATCINGVNGFRCICP--EGPHHPSCYSQVNE----CLSNPCIHGNCTGGLSGYKCLCDA 747
G +N VNG +C P E C V L PC + + + C
Sbjct: 552 GRCYLNTVNG-QCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQ 610
Query: 748 GWVGIN---CEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPC 804
G+ +N C+ D NECL+ C N Y CTC+ G + C S+
Sbjct: 611 GYKRLNLTHCQ-DINECLTLGLCKDAECVNTRGSYLCTCRPGLM---LDPSRSRCVSDKA 666
Query: 805 LN--QGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESP--NFESYTCL 860
++ QG C+ + TC LP + + + CS + C++ P E++ +
Sbjct: 667 ISMLQGLCYRSLGPGTC--TLPLAQRITKQICC-CSRVGKAWGSECEKCPLPGTEAFREI 723
Query: 861 CAPGWQGQRCTIDI--------DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDI 912
C G + DI +E +++P QG PG + +
Sbjct: 724 CPAGHGYTYASSDIRLSMRKAEEEELARP-------PREQGQRSSGALPGPAERQPLRVV 776
Query: 913 DDCL--ANPCQNGGSCMDGVNTFSCLCLPGF-TGDKCQTDMNEC-LSEPCKNGGTCSDYV 968
D A + G G T S P + TG+ M E ++E + T S V
Sbjct: 777 TDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDV 836
Query: 969 -----NSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TG 1019
+C AG V GTCV+ + + C+C G+ +
Sbjct: 837 LVTLSTPGIDRCAAGATNV--------------CGPGTCVNLPDGYRCVCSPGYQLHPSQ 882
Query: 1020 SFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYT------GKNCQTLVNLCSRSPCK 1073
++C + NEC PC +G C++ +G+Y C C GYT + CQ +N C +
Sbjct: 883 AYCTDD-NECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQD-INECEQPGVC 940
Query: 1074 NKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC-DIAASRRGVLVEHLCQHSGVC-----I 1127
+ G C + C C G Y V C DI + C+H G C +
Sbjct: 941 SGGQCTNTEGSYHCECDQG----YIMVRKGHCQDI----------NECRHPGTCPDGRCV 986
Query: 1128 NAGNTHYC-QCPLGYTGSY--CEEQLDECAS-NPCQHGATCSDFIGGYRCECVPGYQGVN 1183
N+ ++ C C GY G C + ++EC + C HG C++ G +RC C GY+ +
Sbjct: 987 NSPGSYTCLACEEGYRGQSGSCVD-VNECLTPGVCAHGK-CTNLEGSFRCSCEQGYEVTS 1044
Query: 1184 CE---YEVDECQNQPCQNGGTCIDLVNHFKCS-CPPG----TRGLLCEENIDDCARGPHC 1235
E +VDEC ++ G C++ F CS C G G CE+ +D+CA P
Sbjct: 1045 DEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACED-LDECAF-PGV 1102
Query: 1236 LNGGQCMDRIGGYSCR-CLPGFA----GERCEGDINECLSNPCSSEGSLDCIQLTNDYLC 1290
G C + G +SC+ C G+ G+ CE D++EC +P SS +C Y C
Sbjct: 1103 CPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDEC-EDPQSSCLGGECKNTVGSYQC 1160
Query: 1291 VCRSAF---TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCG 1347
+C F G CE + + C G C N F C C PGF A +SC
Sbjct: 1161 LCPQGFQLANGTVCEDVNECMGEEHCAPHGECL---NSHGSFFCLCAPGFVSAEGGTSCQ 1217
Query: 1348 QV-KCRK-----GEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQ 1401
V +C G CV+T C C E+G SP G C
Sbjct: 1218 DVDECATTDPCVGGHCVNTEGSFNCLC------ETGFQPSP--ESGEC------------ 1257
Query: 1402 CAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMEN 1461
CE Y P C + C + C C GDC E
Sbjct: 1258 ----VDIDECEDYGDP------VCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDE- 1306
Query: 1462 PWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQG 1521
C++ C + CD + CL CDQG
Sbjct: 1307 ----CANDTMCGSH--GFCDNTDGSFRCL---------------------------CDQG 1333
Query: 1522 CNSEECGWDGLD 1533
GWD +D
Sbjct: 1334 FEISPSGWDCVD 1345
Score = 48.1 bits (113), Expect = 1e-04
Identities = 72/308 (23%), Positives = 101/308 (32%), Gaps = 67/308 (21%)
Query: 278 GVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSE 337
G N +C P WT T + + +P CQN G+C+ CVC +G+ G C E
Sbjct: 165 GRNVCGGQCCPGWTTANSTNHCIKPVCEP-PCQNRGSCSRPQL---CVCRSGFRGARCEE 220
Query: 338 NIDDCAFA---SCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNP 394
I D F S +R + G+ L A S P + T
Sbjct: 221 VIPDEEFDPQNSRLAPRRWAERSPNLRRSSAAGEGTLARAQPPAPQSPPAPQSPPAGT-- 278
Query: 395 LNGQYICTCPQGYKGADCTEDVDECAMANSN----------------------PCEHAG- 431
L+G Q + G T + A A+S P EH
Sbjct: 279 LSGLSQTHPSQQHVGLSRTVRLHPTATASSQLSSNALPPGPGLEQRDGTQQAVPLEHPSS 338
Query: 432 -------------KCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGF 478
K V T C +G+ CE + D T L GG
Sbjct: 339 PWGLNLTEKIKKIKIVFTPTICKQTCARGHCANSCE-----------RGDTTTLYSQGGH 387
Query: 479 TCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSS 538
GF+ C++ PC+N G+C+ R +C CP TG C + I
Sbjct: 388 GHDPKSGFRIYFCQI--------PCLNGGRCI---GRDECWCPANSTGKFCHLPIPQPDR 436
Query: 539 TPCLNGAK 546
P G++
Sbjct: 437 EPPGRGSR 444
Score = 41.6 bits (96), Expect = 0.010
Identities = 39/136 (28%), Positives = 59/136 (43%), Gaps = 19/136 (13%)
Query: 396 NGQYICTCPQGYKGADCT--EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRC 453
NGQ CPQGYK + T +D++EC C+ A +CVNT G++ C C G
Sbjct: 603 NGQL--ECPQGYKRLNLTHCQDINECLTLGL--CKDA-ECVNTRGSYLCTCRPGL---ML 654
Query: 454 EMDINECHSDPCQN--DATCLDKIGGFTC---LCMPGFKGVHCELEINECQSNPCVNNGQ 508
+ + C SD + C +G TC L K + C + + + C +
Sbjct: 655 DPSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSEC---EK 711
Query: 509 C-VDKVNRFQCLCPPG 523
C + F+ +CP G
Sbjct: 712 CPLPGTEAFREICPAG 727
Score = 41.2 bits (95), Expect = 0.013
Identities = 23/58 (39%), Positives = 25/58 (43%), Gaps = 10/58 (17%)
Query: 861 CAPGWQGQRCTIDIDECISK----PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDD 914
C PGW T + CI PC N G C Q +C C GF G CEE I D
Sbjct: 173 CCPGWTTANST---NHCIKPVCEPPCQNRGSCSRPQ---LCVCRSGFRGARCEEVIPD 224
Score = 39.3 bits (90), Expect = 0.049
Identities = 32/96 (33%), Positives = 41/96 (42%), Gaps = 16/96 (16%)
Query: 365 PEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTE----DVDECA 420
P G GL ++ I N C G Y C C +G++ D DV+EC
Sbjct: 1726 PAGFEGL--QAEECGILNGCENGRCVRVRE---GYTCDCFEGFQ-LDAAHMACVDVNECD 1779
Query: 421 MANSNP--CEHAGKCVNTDGAFHCECLKGY---AGP 451
N C H G C NT+G++ C C GY AGP
Sbjct: 1780 DLNGPAVLCVH-GYCENTEGSYRCHCSPGYVAEAGP 1814
Score = 38.1 bits (87), Expect = 0.11
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 10/66 (15%)
Query: 927 MDGVNTFSCLCLPGFTGDKCQTDMNECLSE----PCKNGGTCSDYVNSYTCKCQAGFDGV 982
+ G N C PG+T N C+ PC+N G+CS C C++GF G
Sbjct: 163 LTGRNVCGGQCCPGWT---TANSTNHCIKPVCEPPCQNRGSCS---RPQLCVCRSGFRGA 216
Query: 983 HCENNI 988
CE I
Sbjct: 217 RCEEVI 222
Score = 36.2 bits (82), Expect = 0.41
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 10/63 (15%)
Query: 745 CDAGWVGINCEVDKNECLSN----PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECA 800
C GW N N C+ PCQN G+C C C+ GF+G C+ I +
Sbjct: 173 CCPGWTTAN---STNHCIKPVCEPPCQNRGSCSR---PQLCVCRSGFRGARCEEVIPDEE 226
Query: 801 SNP 803
+P
Sbjct: 227 FDP 229
Score = 36.2 bits (82), Expect = 0.41
Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 5/66 (7%)
Query: 77 GTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVG 136
G C G T + G G D + S F PCLNGG C + RD EC C
Sbjct: 367 GHCANSCERGDTTTLYSQGGHGHDPK-SGFRIYFCQIPCLNGGRC--IGRD--ECWCPAN 421
Query: 137 FTGKEC 142
TGK C
Sbjct: 422 STGKFC 427
Score = 35.8 bits (81), Expect = 0.54
Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 5/63 (7%)
Query: 1051 CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCD--VPNVSCDIA 1108
CP T + + PC+N+G+C + + C+C SG+ GA C+ +P+ D
Sbjct: 174 CPGWTTANSTNHCIKPVCEPPCQNRGSCSRPQL---CVCRSGFRGARCEEVIPDEEFDPQ 230
Query: 1109 ASR 1111
SR
Sbjct: 231 NSR 233
Score = 34.7 bits (78), Expect = 1.2
Identities = 22/60 (36%), Positives = 24/60 (40%), Gaps = 11/60 (18%)
Query: 523 GFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG 582
GF CQI PCLNG +CI EC C TG C I D +P G
Sbjct: 394 GFRIYFCQI--------PCLNGGRCIGRD---ECWCPANSTGKFCHLPIPQPDREPPGRG 442
Score = 34.3 bits (77), Expect = 1.6
Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 5/58 (8%)
Query: 206 QCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDD 263
QC CP T + P PC N G+C + C C GF G+ CE I D
Sbjct: 172 QC-CPGWTTANSTNHCIKPVCEPPCQNRGSCSRPQ----LCVCRSGFRGARCEEVIPD 224
Score = 34.3 bits (77), Expect = 1.6
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 4/56 (7%)
Query: 1174 ECVPGYQGVNC-EYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDD 1228
+C PG+ N + + PCQN G+C C C G RG CEE I D
Sbjct: 172 QCCPGWTTANSTNHCIKPVCEPPCQNRGSCS---RPQLCVCRSGFRGARCEEVIPD 224
Score = 33.9 bits (76), Expect = 2.0
Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 15/96 (15%)
Query: 1141 YTGSYCEEQL--DECASNPCQHGATCSDFI-GGYRCECVPGYQGVNCEYEVDECQNQPCQ 1197
+T + C++ CA N C+ G T + + GG+ + G++ C+ PC
Sbjct: 355 FTPTICKQTCARGHCA-NSCERGDTTTLYSQGGHGHDPKSGFRIYFCQI--------PCL 405
Query: 1198 NGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP 1233
NGG CI +C CP + G C I R P
Sbjct: 406 NGGRCI---GRDECWCPANSTGKFCHLPIPQPDREP 438
Score = 33.5 bits (75), Expect = 2.7
Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 10/90 (11%)
Query: 380 ISNPCHKGALCDTNP---LNGQYIC--TCPQGYKGADCTEDVDECAMANSNPCEHAGKCV 434
+ P GA T P L G+ +C C G+ A+ T + PC++ G C
Sbjct: 145 LGTPQRSGAAPPTPPRGRLTGRNVCGGQCCPGWTTANSTNHCIKPVC--EPPCQNRGSCS 202
Query: 435 NTDGAFHCECLKGYAGPRCEMDINECHSDP 464
C C G+ G RCE I + DP
Sbjct: 203 RPQ---LCVCRSGFRGARCEEVIPDEEFDP 229
Score = 33.5 bits (75), Expect = 2.7
Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 12/59 (20%)
Query: 1251 RCLPGFAGERCEGDINECLSN----PCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFV 1305
+C PG+ N C+ PC + GS QL CVCRS F G CE +
Sbjct: 172 QCCPGWT---TANSTNHCIKPVCEPPCQNRGSCSRPQL-----CVCRSGFRGARCEEVI 222
Score = 33.1 bits (74), Expect = 3.5
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 3/39 (7%)
Query: 1033 PCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSP 1071
PCLN G C+ G C CP TGK C + R P
Sbjct: 403 PCLNGGRCI---GRDECWCPANSTGKFCHLPIPQPDREP 438
Score = 32.0 bits (71), Expect = 7.8
Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 5/33 (15%)
Query: 186 CDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYC 218
C IP C +GG C+ G +C CP TG++C
Sbjct: 400 CQIP--CLNGGRCI---GRDECWCPANSTGKFC 427
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 255 bits (652), Expect = 3e-67
Identities = 232/819 (28%), Positives = 319/819 (38%), Gaps = 147/819 (17%)
Query: 190 GHCQHG------GTCLNLPGSYQCQCPQGFT----------GQYCDSLYVPCAPSPCVNG 233
G CQ G C++ P Y C C GF C + PCAP C N
Sbjct: 480 GMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENS 539
Query: 234 GTCRQTGDFTFECNCLPGFEGSTCER---NIDDCPNHRCQ---NGGVCVDGVNTYNCRCP 287
+F C C PGF ++D+C HR + G C + ++ C CP
Sbjct: 540 PG-------SFRCVCGPGFRAGPRAAECLDVDEC--HRVPPPCDLGRCENTPGSFLCVCP 590
Query: 288 PQWT----GQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCA 343
+ G C +DVDEC P C G C N G + CVC G+ G C E++D+CA
Sbjct: 591 AGYQAAPHGASC-QDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECA 648
Query: 344 FAS--CTPGSTCIDRVASFSCMCPEG----KAGLLCHLDDACISNP--CHKGALCDTNPL 395
C PG C + SF C CP G G C D C +P C G +T
Sbjct: 649 QEPPPCGPGR-CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTE-- 705
Query: 396 NGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE-CLKGYA- 449
G + C CP G++ G++C EDVDEC + P + +CVN+ G+F C C G+
Sbjct: 706 -GSFQCVCPMGFQPNTAGSEC-EDVDECENHLACPGQ---ECVNSPGSFQCRTCPSGHHL 760
Query: 450 -GPRCEMDINECHSD--PCQNDATCLDKIGGFTCLCMPGFKGVHCE----LEINEC-QSN 501
RC D++EC S PC C + G F C C PG++ ++NEC + +
Sbjct: 761 HRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD 819
Query: 502 PCVNNGQCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQ 557
C +G+C++ F C C PG+ G C +D+D+CS C + +EC
Sbjct: 820 FCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECI 878
Query: 558 CATGFTG----VLCEENIDNC---DPDPCHHGQCQDGIDSYTCI--CNPGYMGAI--CSD 606
C G C + +D C P C +C++ SY C+ C+PGY D
Sbjct: 879 CPPGHRAGPDLASCLD-VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD 937
Query: 607 QIDEC--YSSPCLNDGRCIDLVNGYQCN--CQPG---TSGVNCEINFDDCASNPCI--HG 657
+DEC Y RC + Y+C C PG T G C+ + D+C + H
Sbjct: 938 DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHA 996
Query: 658 ICMDGINRYSCVCSPGFTGQRCN---IDIDECASNPCRKGATCINGVNG-FRCICPEGPH 713
+C + + C+C G+ G R +D++EC + GA V G F C+CP P
Sbjct: 997 VCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 1056
Query: 714 HPSCYSQVNECLSNPCIHGNCTGG------------------LSGYKCLCDAGWVGINCE 755
C+ G G L G VG
Sbjct: 1057 EFD--PMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG-- 1112
Query: 756 VDKNECLSNPCQNGGTCDNL----VNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF 811
+ EC + CDN+ V C C G +G+ I +C +
Sbjct: 1113 --RRECYFDTAA-PDACDNILARNVTWQECCCTVG-EGWGSGCRIQQCPGTETAEYQSLC 1168
Query: 812 DDISGYTC---HCVLPYTGKNCQTVL-APCSPNPCENAAVCKESPNFESYTCLCAPGW-- 865
GY L CQ C C N A Y+C C+ G+
Sbjct: 1169 PHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTA--------PGYSCYCSNGYYY 1220
Query: 866 --QGQRCTIDIDECI-SKPCMNHGLCHNTQGSYMCECPP 901
Q C ID DEC +P G C NT GSY C C P
Sbjct: 1221 HTQRLEC-IDNDECADEEPACEGGRCVNTVGSYHCTCEP 1258
Score = 253 bits (647), Expect = 1e-66
Identities = 290/1094 (26%), Positives = 428/1094 (39%), Gaps = 183/1094 (16%)
Query: 273 GVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW-- 330
G C G N C EDVDEC CQ+G CAN GGY CVC +G+
Sbjct: 275 GPCPTGFERVNGSC----------EDVDECATG-GRCQHG-ECANTRGGYTCVCPDGFLL 322
Query: 331 --SGDDC-SENIDDCAFASC----TPGSTCIDRVASFS---CMCPE-GKA-GLLCHLDDA 378
S C S+++ A C G + + + + C C GKA G C L
Sbjct: 323 DSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPP 382
Query: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438
S + +C P G + Y ++ ++ S P + G
Sbjct: 383 FGSEGFRE--ICPAGP--GYHYSASDLRYNTRPLGQEPPRVSL--SQPRTLPATSRPSAG 436
Query: 439 AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP--GFKGVHCELEIN 496
L+ PR DP L I +T +P G C+
Sbjct: 437 FLPTHRLEPRPEPR---------PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQ 487
Query: 497 ECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCSST--PCLNGAKCIDH 550
C C++ + + + C C GF G C ID+D+C PC G +C +
Sbjct: 488 VCGPGRCIS------RPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENS 539
Query: 551 PNGYECQCATGF-TGVLCEE--NIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----G 601
P + C C GF G E ++D C P PC G+C++ S+ C+C GY G
Sbjct: 540 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 599
Query: 602 AICSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASN--PCIHGI 658
A C D +DEC SP L G C +L ++C C G G CE + D+CA PC G
Sbjct: 600 ASCQD-VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR 658
Query: 659 CMDGINRYSCVCSPGF----TGQRCNIDIDECASN--PCRKGATCINGVNGFRCICPEGP 712
C + + C C GF G C D+DECA + PC G C N F+C+CP G
Sbjct: 659 CDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYG-RCENTEGSFQCVCPMGF 716
Query: 713 HHPSCYSQ---VNECLSN-PCIHGNCTGGLSGYKC-LCDAG---WVGINCEVDKNECLSN 764
+ S+ V+EC ++ C C ++C C +G G +VD+ +
Sbjct: 717 QPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAP 776
Query: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQ----VNIDECASNP-CLNQGTCFDDISGYTC 819
PC G C N +RC+C G++ + + +++EC C G C + + C
Sbjct: 777 PCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFAC 836
Query: 820 HCVLPY----TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQG---QRCTI 872
C Y G +C V CS + +C + S+ C+C PG + +
Sbjct: 837 TCAPGYRPGPRGASCLDV-DECSEEDLCQSGICTNTDG--SFECICPPGHRAGPDLASCL 893
Query: 873 DIDECISK-PCM-NHGLCHNTQGSYMC--ECPPGF-SGMD--CEEDIDDCLANPCQNGGS 925
D+DEC + P + C N+ GSY C +C PG+ +G + C +D+D+C + G+
Sbjct: 894 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC-DDVDECQEYGPEICGA 952
Query: 926 --CMDGVNTFSC--LCLPGF---TGDKCQTDMNECLSEP-CKNGGTCSDYVNSYTCKCQA 977
C + ++ C C PG+ G CQ D++EC + C C + S+ C C
Sbjct: 953 QRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQ 1011
Query: 978 GF----DGVHCENNINEC-TESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH 1032
G+ DG HC ++NEC T C + SF C+CP
Sbjct: 1012 GYEGARDGRHCV-DVNECETLQGVCGAALCENVEGSFLCVCP------------------ 1052
Query: 1033 PCLNEGTCVDGLGTYRCSCPLGYTG--KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCP 1090
N D + T RC P G Q P + + ++ + P
Sbjct: 1053 ---NSPEEFDPM-TGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGP 1108
Query: 1091 SGWAGAYCDVPNVSCDIAAS--RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEE 1148
G C + D + R V + C G +G QCP T Y
Sbjct: 1109 VGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSG-CRIQQCPGTETAEY--- 1164
Query: 1149 QLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQ---NQPCQNGGTCIDL 1205
+ C HG GY + ++ +VDECQ +Q C++ G C++
Sbjct: 1165 ------QSLCPHGR-------GY----LAPSGDLSLRRDVDECQLFRDQVCKS-GVCVNT 1206
Query: 1206 VNHFKCSCPPG----TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
+ C C G T+ L C +N D+CA GG+C++ +G Y C C P
Sbjct: 1207 APGYSCYCSNGYYYHTQRLECIDN-DECADEEPACEGGRCVNTVGSYHCTCEPPLV---L 1262
Query: 1262 EGDINECLSNPCSS 1275
+G C+SN S
Sbjct: 1263 DGSQRRCVSNESQS 1276
Score = 245 bits (626), Expect = 3e-64
Identities = 236/876 (26%), Positives = 351/876 (40%), Gaps = 189/876 (21%)
Query: 566 LCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDL 625
LC E + N + G C G + C + +DEC + G C +
Sbjct: 259 LCSERLGNSERVSAPDGPCPTGFERVNGSC----------EDVDECATGGRCQHGECANT 308
Query: 626 VNGYQCNCQPG----TSGVNC-EINFDDCASNPCIH----GIC----MDGINRYSCVCSP 672
GY C C G +S +C + A PC G C + I + C CS
Sbjct: 309 RGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSR 368
Query: 673 GFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGP--HHPSCYSQVNE------- 723
G+ C G GFR ICP GP H+ + + N
Sbjct: 369 --VGKAWGRGCQLCPP----------FGSEGFREICPAGPGYHYSASDLRYNTRPLGQEP 416
Query: 724 ---CLSNPCIHGNCTGGLSGY----------------------KCLCDAGWVGINCEVDK 758
LS P + +G+ W G E+ +
Sbjct: 417 PRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTG--PEIPE 474
Query: 759 NECLSNPCQNG------GTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASNPCLNQG 808
+ S CQ G C + +GY C C GF+ G C +++DEC P
Sbjct: 475 SGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVP----- 528
Query: 809 TCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ-G 867
PC+P CEN SP S+ C+C PG++ G
Sbjct: 529 --------------------------PPCAPGRCEN------SPG--SFRCVCGPGFRAG 554
Query: 868 QRCT--IDIDEC--ISKPCMNHGLCHNTQGSYMCECPPGFS----GMDCEEDIDDCLANP 919
R +D+DEC + PC + G C NT GS++C CP G+ G C +D+D+C +P
Sbjct: 555 PRAAECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDECTQSP 612
Query: 920 CQNG-GSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNG-GTCSDYVNSYTCKCQA 977
G G+C + +F C+C GF G C+ D++EC EP G G C + S+ C C A
Sbjct: 613 GLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPA 672
Query: 978 GF----DGVHCENNINECTES--SCFNGGTCVDGINSFSCLCPVGF----TGSFCLHEIN 1027
GF G C+ +++EC S C G C + SF C+CP+GF GS C +++
Sbjct: 673 GFRSRGPGAPCQ-DVDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSEC-EDVD 729
Query: 1028 ECSSHPCLNEGTCVDGLGTYRC-SCPLG-YTGKNCQTLVNLCSRS--PCKNKGTCVQKKA 1083
EC +H CV+ G+++C +CP G + + T V+ CS PC G C +
Sbjct: 730 ECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEG 789
Query: 1084 ESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY-- 1141
+C C G+ A P D+ G C G C+N + C C GY
Sbjct: 790 SFRCSCAPGYR-APSGRPGPCADVNECLEG----DFCFPHGECLNTDGSFACTCAPGYRP 844
Query: 1142 --TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQG----VNCEYEVDECQNQ- 1194
G+ C + +DEC+ C++ G + C C PG++ +C +VDEC+ +
Sbjct: 845 GPRGASCLD-VDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERG 902
Query: 1195 PCQNGG-TCIDLVNHFKC--SCPPGTRG---LLCEENIDDCAR-GPHCLNGGQCMDRIGG 1247
P G C + ++C C PG C++ +D+C GP +C + G
Sbjct: 903 PALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDD-VDECQEYGPEICGAQRCENTPGS 961
Query: 1248 YSC--RCLPGF---AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVC----RSAFTG 1298
Y C C PG+ G C+ D++EC + ++ C L + C+C A G
Sbjct: 962 YRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAV-CQNLPGSFQCLCDQGYEGARDG 1019
Query: 1299 RHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCP 1334
RHC V+ C + + G A+ N+ F+C CP
Sbjct: 1020 RHC-VDVNECETLQGVCG--AALCENVEGSFLCVCP 1052
Score = 241 bits (616), Expect = 5e-63
Identities = 266/969 (27%), Positives = 370/969 (38%), Gaps = 220/969 (22%)
Query: 711 GPHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNEC--L 762
GP P C NP C G C SGY C CD+G+ G C +D +EC +
Sbjct: 469 GPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRV 527
Query: 763 SNPCQNGGTCDNLVNGYRCTCKKGFKG----YNCQVNIDECASNPCLNQGTCFDDISGYT 818
PC G C+N +RC C GF+ C +++DEC
Sbjct: 528 PPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAEC-LDVDEC------------------- 566
Query: 819 CHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDI 874
H V P PC CEN S+ C+C G+Q G C D+
Sbjct: 567 -HRVPP-----------PCDLGRCENTP--------GSFLCVCPAGYQAAPHGASCQ-DV 605
Query: 875 DECISKPCM-NHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNG-GSCMDGVNT 932
DEC P + G C N GS+ C CP GF G CEED+D+C P G G C + +
Sbjct: 606 DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGS 665
Query: 933 FSCLCLPGF----TGDKCQTDMNECL-SEPCKNGGTCSDYVNSYTCKCQAGFD----GVH 983
F C C GF G CQ D++EC S P G C + S+ C C GF G
Sbjct: 666 FHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSE 724
Query: 984 CENNINECTESSCFNGGTCVDGINSFSC-LCPVGFTGSFCLH-----EINECSS--HPCL 1035
CE +++EC G CV+ SF C CP G LH +++ECSS PC
Sbjct: 725 CE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHH----LHRGRCTDVDECSSGAPPCG 779
Query: 1036 NEGTCVDGLGTYRCSCPLGYTGKN-----CQTLVNLCSRSPCKNKGTCVQKKAESQCLCP 1090
G C + G++RCSC GY + C + C G C+ C C
Sbjct: 780 PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 839
Query: 1091 SGW----AGAYC-DVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG-- 1143
G+ GA C DV S E LCQ SG+C N + C CP G+
Sbjct: 840 PGYRPGPRGASCLDVDECS-----------EEDLCQ-SGICTNTDGSFECICPPGHRAGP 887
Query: 1144 --SYCEEQLDECAS-NPCQHGA-TCSDFIGGYRC--ECVPGYQG---VNCEYEVDECQNQ 1194
+ C + +DEC P G+ C + G YRC +C PGY C+ +VDECQ
Sbjct: 888 DLASCLD-VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEY 945
Query: 1195 PCQNGGT--CIDLVNHFKC--SCPPG---TRGLLCEENIDDCARGPHCLNGGQCMDRIGG 1247
+ G C + ++C +C PG T G C++ +D+C C C + G
Sbjct: 946 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQD-VDECRNRSFCGAHAVCQNLPGS 1004
Query: 1248 YSCRCLPGFAGERCEG----DINEC--LSNPCSSEGSLDCIQLTNDYLCVCRSA------ 1295
+ C C G+ G R +G D+NEC L C G+ C + +LCVC ++
Sbjct: 1005 FQCLCDQGYEGAR-DGRHCVDVNECETLQGVC---GAALCENVEGSFLCVCPNSPEEFDP 1060
Query: 1296 FTGR------HCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCP------PGFSGAR-- 1341
TGR TF PQ P + + + P + R P P SG R
Sbjct: 1061 MTGRCVPPRTSAGTFPGSQPQAP----ASPVLPARPPPPPLPRRPSTPRQGPVGSGRREC 1116
Query: 1342 -----CQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPP 1396
+C + R + C C SGC C + Q P
Sbjct: 1117 YFDTAAPDACDNILAR-------NVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCP 1169
Query: 1397 YYSCQCAPP--------------FSGSRCELYTAPPSTPPATCLSQYCAD------KARD 1436
+ AP F C+ + P +C YC++ + +
Sbjct: 1170 HGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC---YCSNGYYYHTQRLE 1226
Query: 1437 GVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDN--- 1493
+ ++ C +GG C T+ + C PL D +C + N + L DN
Sbjct: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL-VLDGSQRRC--VSNESQSLDDNLGV 1283
Query: 1494 -FECQGNSKTCKYDKYCADHFKDNHCDQGCNSEEC------GWDGLDCAADQPENLAEGT 1546
++ G C + + D+ EC W G+DCA ++ +
Sbjct: 1284 CWQEVGADLVCSHPR----------LDRQATYTECCCLYGEAW-GMDCALCPAQDSDDFE 1332
Query: 1547 LVIVVLMPP 1555
+ VL PP
Sbjct: 1333 ALCNVLRPP 1341
Score = 218 bits (555), Expect = 6e-56
Identities = 234/847 (27%), Positives = 335/847 (39%), Gaps = 140/847 (16%)
Query: 68 CEKNRCQNG-GTCVAQAMLGKATCRCASGFT----GEDCQYSTSHPCFVSRPCLNGGTCH 122
C++N G G C+++ TC C SGF G C V PC G C
Sbjct: 482 CQRNPQVCGPGRCISRP--SGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCE 537
Query: 123 MLSRDTYECTCQVGFTG----KECQWTDAC--LSHPCANGSTCTTVANQFSCKCLTGFT- 175
S ++ C C GF EC D C + PC G C F C C G+
Sbjct: 538 N-SPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQA 595
Query: 176 ---GQKCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCA--PSP 229
G C+ DV+EC PG C G C NLPGS++C CP GF G C+ CA P P
Sbjct: 596 APHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPP 653
Query: 230 CVNGGTCRQTGDFTFECNCLPGFE----GSTCERNIDDCPNH--RCQNGGVCVDGVNTYN 283
C G C T +F C C GF G+ C+ ++D+C C G C + ++
Sbjct: 654 C-GPGRCDNTAG-SFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGR-CENTEGSFQ 709
Query: 284 CRCP----PQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGC-VCVNG--WSGDDCS 336
C CP P G C EDVDEC + + G C N G + C C +G C+
Sbjct: 710 CVCPMGFQPNTAGSEC-EDVDEC--ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCT 766
Query: 337 ENIDDCAFAS--CTPGSTCIDRVASFSCMC------PEGKAGLLCHLDDACISNPCHKGA 388
+ +D+C+ + C P C + SF C C P G+ G +++ + C
Sbjct: 767 D-VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHG 825
Query: 389 LCDTNPLNGQYICTCPQGY----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC 444
C +G + CTC GY +GA C DVDEC + + C+ +G C NTDG+F C C
Sbjct: 826 ECLNT--DGSFACTCAPGYRPGPRGASCL-DVDEC--SEEDLCQ-SGICTNTDGSFECIC 879
Query: 445 LKGY-AGPRCE--MDINEC--HSDPCQNDATCLDKIGGFTCL--CMPGFKG---VHCELE 494
G+ AGP +D++EC C + G + C+ C PG+ C+ +
Sbjct: 880 PPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-D 938
Query: 495 INECQS-NPCVNNGQ-CVDKVNRFQC--LCPPGF---TGPVCQIDIDDCSSTP-CLNGAK 546
++ECQ P + Q C + ++C C PG+ G CQ D+D+C + C A
Sbjct: 939 VDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAV 997
Query: 547 CIDHPNGYECQCATGFTGVLCEE---NIDNCD--PDPCHHGQCQDGIDSYTCIC------ 595
C + P ++C C G+ G +++ C+ C C++ S+ C+C
Sbjct: 998 CQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 1057
Query: 596 ---------NPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGV-NCEIN 645
P + +SP L + + G G E
Sbjct: 1058 FDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY 1117
Query: 646 FDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFR 705
FD A + C I + C C+ G G I +C + ++
Sbjct: 1118 FDTAAPDAC-DNILARNVTWQECCCTVG-EGWGSGCRIQQCPGTETAE----------YQ 1165
Query: 706 CICPEGPHH------PSCYSQVNEC---LSNPCIHGNCTGGLSGYKCLCDAGWV----GI 752
+CP G + S V+EC C G C GY C C G+ +
Sbjct: 1166 SLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRL 1225
Query: 753 NCEVDKNECL-SNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCL----NQ 807
C +D +EC P GG C N V Y CTC+ Q C SN N
Sbjct: 1226 EC-IDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQ---RRCVSNESQSLDDNL 1281
Query: 808 GTCFDDI 814
G C+ ++
Sbjct: 1282 GVCWQEV 1288
Score = 162 bits (410), Expect = 4e-39
Identities = 153/517 (29%), Positives = 198/517 (38%), Gaps = 114/517 (22%)
Query: 20 AAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCK---------CPEGFLGEYC-------- 62
AAP H C+D E + G+C G G CK CP GF G C
Sbjct: 595 AAP-HGASCQDVDECTQSPGLC-----GRGACKNLPGSFRCVCPAGFRGSACEEDVDECA 648
Query: 63 QHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGF----TGEDCQYSTSHPCFVSRPCLNG 118
Q PC RC N G C C +GF G CQ C S P
Sbjct: 649 QEPPPCGPGRCDN--------TAGSFHCACPAGFRSRGPGAPCQ--DVDECARSPPPCTY 698
Query: 119 GTCHMLSRDTYECTCQVGF----TGKECQWTDACLSHPCANGSTCTTVANQFSCK-CLTG 173
G C + +++C C +GF G EC+ D C +H G C F C+ C +G
Sbjct: 699 GRCEN-TEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSG 757
Query: 174 --FTGQKCETDVNECDIPG-HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAP-SP 229
+C TDV+EC C G C N GS++C C G+ PCA +
Sbjct: 758 HHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAP--SGRPGPCADVNE 814
Query: 230 CVNGGTCRQTG-----DFTFECNCLPGF----EGSTCERNIDDCPNHRCQNGGVCVDGVN 280
C+ G C G D +F C C PG+ G++C ++D+C G+C +
Sbjct: 815 CLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDG 873
Query: 281 TYNCRCPPQWTG----QFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCS 336
++ C CPP C DVDEC + A C N G Y CV
Sbjct: 874 SFECICPPGHRAGPDLASCL-DVDECRERGPALCGSQRCENSPGSYRCV----------- 921
Query: 337 ENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA-LCDTNPL 395
C PG G G +D+ P GA C+ P
Sbjct: 922 --------RDCDPGYHA-------------GPEGTCDDVDECQEYGPEICGAQRCENTP- 959
Query: 396 NGQYICT--CPQGYK---GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
G Y CT C GY+ G C +DVDEC N + C C N G+F C C +GY G
Sbjct: 960 -GSYRCTPACDPGYQPTPGGGC-QDVDEC--RNRSFCGAHAVCQNLPGSFQCLCDQGYEG 1015
Query: 451 PR----CEMDINECHS-DPCQNDATCLDKIGGFTCLC 482
R C +D+NEC + A C + G F C+C
Sbjct: 1016 ARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVC 1051
Score = 115 bits (288), Expect = 5e-25
Identities = 176/678 (25%), Positives = 255/678 (37%), Gaps = 132/678 (19%)
Query: 923 GGSC---MDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF 979
GG C + G+ T C G +++C + C S+ V++ C GF
Sbjct: 228 GGECASPLPGLRTQEVCC----RGAGLAWGVHDC--QLCSERLGNSERVSAPDGPCPTGF 281
Query: 980 DGVH--CENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCL--HEINECSS 1031
+ V+ CE+ ++EC G C + ++C+CP GF + S C+ H I+E
Sbjct: 282 ERVNGSCED-VDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA-- 338
Query: 1032 HPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSR-SPCKNKG--TCVQKKAES-QC 1087
+G C L CS P+ +N + CSR +G C +E +
Sbjct: 339 -----KGPCFRVLRDGGCSLPI---LRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 390
Query: 1088 LCPSGWAGAYC-------------DVPNVSCD----IAASRR---GVLVEHLCQHSGVCI 1127
+CP+G Y + P VS + A+ R G L H +
Sbjct: 391 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPE-P 449
Query: 1128 NAGNTHYCQCPLGYTGSYCEEQLDEC--ASNPCQHG------ATCSDFIGGYRCECVPGY 1179
+ PL ++ ++ E +S CQ C GY C C G+
Sbjct: 450 RPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGF 509
Query: 1180 ----QGVNCEYEVDECQN--QPCQNGGTCIDLVNHFKCSCPPGTR-GLLCEE--NIDDCA 1230
QG C +VDEC+ PC G C + F+C C PG R G E ++D+C
Sbjct: 510 RLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH 567
Query: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFA----GERCEGDINECLSNPCSSEGSLDCIQLTN 1286
R P + G+C + G + C C G+ G C+ D++EC +P G C L
Sbjct: 568 RVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSP-GLCGRGACKNLPG 625
Query: 1287 DYLCVCRSAFTGRHCETFVDVCPQMPCLNG-GTCAVASNMPDGFICRCPPGF----SGAR 1341
+ CVC + F G CE VD C Q P G G C N F C CP GF GA
Sbjct: 626 SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRC---DNTAGSFHCACPAGFRSRGPGAP 682
Query: 1342 CQ--SSCGQ--VKCRKGEQCVHTASGPRCFCP---SPRDCESGCAS-SPCQHGGSCHPQ- 1392
CQ C + C G +C +T +C CP P S C C++ +C Q
Sbjct: 683 CQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQE 741
Query: 1393 --RQPPYYSCQCAPP---FSGSRCE-----LYTAPPSTP-----------PATCLSQYCA 1431
P + C+ P RC APP P +C Y A
Sbjct: 742 CVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 801
Query: 1432 DKARDGVC---DEACNSHACQWDGGDCSLTMENPWANCSSP--------LPCWDYINNQC 1480
R G C +E C + G+C L + +A +P C D
Sbjct: 802 PSGRPGPCADVNECLEGDFC-FPHGEC-LNTDGSFACTCAPGYRPGPRGASCLDVDECSE 859
Query: 1481 DELCNTVEC--LFDNFEC 1496
++LC + C +FEC
Sbjct: 860 EDLCQSGICTNTDGSFEC 877
Score = 83.6 bits (205), Expect = 2e-15
Identities = 124/481 (25%), Positives = 164/481 (34%), Gaps = 120/481 (24%)
Query: 25 ALQCRDGYEP------------CVNEGMC----VTYHNGTGYCKCPEGFLG--------- 59
A C GY P C E +C T +G+ C CP G
Sbjct: 835 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 894
Query: 60 -EYCQHRDP--CEKNRCQNGG---TCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR 113
+ C+ R P C RC+N CV G + ++CQ C R
Sbjct: 895 VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR 954
Query: 114 PCLNGGTCHMLSRDTYECT--CQVGFT---GKECQWTDACLSHP-CANGSTCTTVANQFS 167
C N + +Y CT C G+ G CQ D C + C + C + F
Sbjct: 955 -CEN-------TPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQ 1006
Query: 168 CKCLTGFTGQK----CETDVNECD-IPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLY 222
C C G+ G + C DVNEC+ + G C C N+ GS+ C CP + + D +
Sbjct: 1007 CLCDQGYEGARDGRHC-VDVNECETLQGVCG-AALCENVEGSFLCVCPN--SPEEFDPMT 1062
Query: 223 VPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTY 282
C P P + GT + LP P
Sbjct: 1063 GRCVP-PRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTP----------------- 1104
Query: 283 NCRCPPQWTGQFCTEDVDECLLQ---PNACQNGGTCANRNGGYGCVCV--NGWSGDDCSE 337
R P +G+ EC P+AC N A C C GW G C
Sbjct: 1105 --RQGPVGSGR------RECYFDTAAPDACDN--ILARNVTWQECCCTVGEGW-GSGC-- 1151
Query: 338 NIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-------DAC---ISNPCHKG 387
I C PG+ A + +CP G+ L D D C C G
Sbjct: 1152 RIQQC------PGT----ETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1201
Query: 388 ALCDTNPLNGQYICTCPQGY----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE 443
+T P Y C C GY + +C D DEC A+ P G+CVNT G++HC
Sbjct: 1202 VCVNTAP---GYSCYCSNGYYYHTQRLECI-DNDEC--ADEEPACEGGRCVNTVGSYHCT 1255
Query: 444 C 444
C
Sbjct: 1256 C 1256
Score = 62.8 bits (151), Expect = 4e-09
Identities = 113/483 (23%), Positives = 170/483 (35%), Gaps = 89/483 (18%)
Query: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
C NGG CV CLCP F G FC +++ + P V GL + PL
Sbjct: 90 CHNGGVCV---KPDRCLCPPDFAGKFC--QLHSSGARP---PAPAVPGLTRSVYTMPLAN 141
Query: 1056 TGKNCQTLVNLCS-RSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGV 1114
+ + ++ S + + V + E W A + +A +
Sbjct: 142 HRDDEHGVASMVSVHVEHPQEASVVVHQVER---VSGPWEEADAEA------VARAEAAA 192
Query: 1115 LVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCE 1174
E ++ + +A G+ YC +L G C+ + G R +
Sbjct: 193 RAEAAAPYTVLAQSAPREDGYSDASGF--GYCFREL---------RGGECASPLPGLRTQ 241
Query: 1175 CVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL--LCEENIDDCARG 1232
V +G + V +CQ + G + + V+ CP G + CE+ +D+CA G
Sbjct: 242 EV-CCRGAGLAWGVHDCQLCSERLGNS--ERVSAPDGPCPTGFERVNGSCED-VDECATG 297
Query: 1233 PHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTND----- 1287
C + G+C + GGY+C C GF + + C+S SE C ++ D
Sbjct: 298 GRCQH-GECANTRGGYTCVCPDGFL---LDSSRSSCISQHVISEAKGPCFRVLRDGGCSL 353
Query: 1288 --------YLCVCR--SAFTGRHC--------ETFVDVCPQMPCLNGGTCAVASN-MPDG 1328
+C C GR C E F ++CP P + + N P G
Sbjct: 354 PILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLG 413
Query: 1329 ----FICRCPPGFSGARCQSSCGQVKCR----KGEQCVHTASGPRCFCPS------PRDC 1374
+ P A + S G + + E GP PS P
Sbjct: 414 QEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIP 473
Query: 1375 ESGCASSPCQHGGS-CHPQR---QPPYYSCQCAPPF----SGSRC----ELYTAPPSTPP 1422
ESG +S CQ C P R +P Y+C C F G+RC E PP P
Sbjct: 474 ESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAP 533
Query: 1423 ATC 1425
C
Sbjct: 534 GRC 536
Score = 52.0 bits (123), Expect = 7e-06
Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 14/104 (13%)
Query: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRC 453
P G Y + + Y+ + +EC + + C + G+CV F C C GY
Sbjct: 1449 PEGGSYAGSLAEPYEELEA----EECGILDG--CTN-GRCVRVPEGFTCRCFDGYRLDMT 1501
Query: 454 EM---DINECH----SDPCQNDATCLDKIGGFTCLCMPGFKGVH 490
M DINEC + P +A CL+ G F C+C PGF H
Sbjct: 1502 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1545
Score = 47.0 bits (110), Expect = 2e-04
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 11/85 (12%)
Query: 449 AGPRCEMDINECHS-DPCQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQ---- 499
A P E++ EC D C N C+ GFTC C G++ + C ++INEC
Sbjct: 1459 AEPYEELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEA 1516
Query: 500 SNPCVNNGQCVDKVNRFQCLCPPGF 524
++P N +C++ F+C+C PGF
Sbjct: 1517 ASPLCVNARCLNTDGSFRCICRPGF 1541
Score = 46.6 bits (109), Expect = 3e-04
Identities = 24/46 (52%), Positives = 25/46 (54%), Gaps = 4/46 (8%)
Query: 170 CLTGF--TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF 213
C TGF CE DV+EC G CQHG C N G Y C CP GF
Sbjct: 277 CPTGFERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 320
Score = 44.3 bits (103), Expect = 0.002
Identities = 27/82 (32%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 153 CANGSTCTTVANQFSCKCLTGF----TGQKCETDVNECDIPGHCQH---GGTCLNLPGSY 205
C NG C V F+C+C G+ T C D+NECD CLN GS+
Sbjct: 1476 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARCLNTDGSF 1533
Query: 206 QCQCPQGFTGQYCDSLYVPCAP 227
+C C GF + P P
Sbjct: 1534 RCICRPGFAPTHQPHHCAPARP 1555
Score = 43.5 bits (101), Expect = 0.003
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 16/87 (18%)
Query: 643 EINFDDCAS-NPCIHGICMDGINRYSCVCSPGF----TGQRCNIDIDEC----ASNPCRK 693
E+ ++C + C +G C+ ++C C G+ T C +DI+EC A++P
Sbjct: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1522
Query: 694 GATCINGVNGFRCICPEG------PHH 714
A C+N FRCIC G PHH
Sbjct: 1523 NARCLNTDGSFRCICRPGFAPTHQPHH 1549
Score = 43.1 bits (100), Expect = 0.003
Identities = 39/136 (28%), Positives = 57/136 (41%), Gaps = 24/136 (17%)
Query: 507 GQCVDKVNRFQCLCP-PGF-TGPVC------QIDIDDCS-STPCLNGAKCIDHPNGYECQ 557
G C ++ +C P PG T VC + DC + L ++ + P+G
Sbjct: 220 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDG---P 276
Query: 558 CATGFTGV--LCEENIDNCDPDP-CHHGQCQDGIDSYTCICNPGYM-----GAICSDQID 609
C TGF V CE+ +D C C HG+C + YTC+C G++ + S +
Sbjct: 277 CPTGFERVNGSCED-VDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 335
Query: 610 ECYSSPC---LNDGRC 622
PC L DG C
Sbjct: 336 SEAKGPCFRVLRDGGC 351
Score = 43.1 bits (100), Expect = 0.003
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 10/82 (12%)
Query: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDNCDPDP---- 578
P +++ ++C +C+ P G+ C+C G+ T + C + I+ CD
Sbjct: 1461 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASP 1519
Query: 579 -CHHGQCQDGIDSYTCICNPGY 599
C + +C + S+ CIC PG+
Sbjct: 1520 LCVNARCLNTDGSFRCICRPGF 1541
Score = 42.4 bits (98), Expect = 0.006
Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 11/104 (10%)
Query: 808 GTCFDDISGYTCHCVLPYTGKN---CQTVLAPCSPNPCENAAVCKE----SPNFESYTCL 860
G CF ++ G C LP C+ + C+ +C E S +
Sbjct: 220 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQ---LCSERLGNSERVSAPDGP 276
Query: 861 CAPGWQGQRCTI-DIDECISKPCMNHGLCHNTQGSYMCECPPGF 903
C G++ + D+DEC + HG C NT+G Y C CP GF
Sbjct: 277 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGF 320
Score = 41.2 bits (95), Expect = 0.013
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 385 HKGALCDTNPLNGQYICT----CPQGYKGADCT-EDVDECAMANSNPCEHAGKCVNTDGA 439
H LC N + + CP G++ + + EDVDECA C+H G+C NT G
Sbjct: 255 HDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR--CQH-GECANTRGG 311
Query: 440 FHCECLKGY 448
+ C C G+
Sbjct: 312 YTCVCPDGF 320
Score = 41.2 bits (95), Expect = 0.013
Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 10/81 (12%)
Query: 1185 EYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDC----ARGPHCL 1236
E E +EC G C+ + F C C G R + C + I++C A P C+
Sbjct: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASPLCV 1522
Query: 1237 NGGQCMDRIGGYSCRCLPGFA 1257
N +C++ G + C C PGFA
Sbjct: 1523 NA-RCLNTDGSFRCICRPGFA 1542
Score = 40.8 bits (94), Expect = 0.017
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 7/57 (12%)
Query: 855 ESYTCLCAPGWQ---GQRCTIDIDEC----ISKPCMNHGLCHNTQGSYMCECPPGFS 904
E +TC C G++ + +DI+EC + P + C NT GS+ C C PGF+
Sbjct: 1486 EGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1542
Score = 40.4 bits (93), Expect = 0.022
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 8/76 (10%)
Query: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPG-----TSGVNCEINFDD---CASNPCIHGI 658
+ +EC +GRC+ + G+ C C G T +IN D AS C++
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
Query: 659 CMDGINRYSCVCSPGF 674
C++ + C+C PGF
Sbjct: 1526 CLNTDGSFRCICRPGF 1541
Score = 38.9 bits (89), Expect = 0.063
Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 1223 EENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG---DINECLSNPCSSEGSL 1279
E ++C C NG +C+ G++CRC G+ + DINEC +S +
Sbjct: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
Query: 1280 D--CIQLTNDYLCVCRSAFTGRH 1300
+ C+ + C+CR F H
Sbjct: 1523 NARCLNTDGSFRCICRPGFAPTH 1545
Score = 38.9 bits (89), Expect = 0.063
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 15/83 (18%)
Query: 180 ETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC----------APSP 229
E + EC I C +G C+ +P + C+C F G D + C A SP
Sbjct: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1519
Query: 230 CVNGGTCRQTGDFTFECNCLPGF 252
C T D +F C C PGF
Sbjct: 1520 LCVNARCLNT-DGSFRCICRPGF 1541
Score = 38.1 bits (87), Expect = 0.11
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 20/96 (20%)
Query: 947 QTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCEN------NINECTESS---- 995
+ + EC + + C NG C +TC+C FDG + +INEC E+
Sbjct: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1519
Query: 996 -CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECS 1030
C N C++ SF C+C GF + H+ + C+
Sbjct: 1520 LCVNA-RCLNTDGSFRCICRPGFAPT---HQPHHCA 1551
Score = 37.4 bits (85), Expect = 0.18
Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 17/88 (19%)
Query: 444 CLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPC 503
C+ G G RC ++ + A GG PGF+ C L C
Sbjct: 45 CVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGG------PGFRAFLCPLI--------C 90
Query: 504 VNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
N G CV K +R CLCPP F G CQ+
Sbjct: 91 HNGGVCV-KPDR--CLCPPDFAGKFCQL 115
Score = 37.0 bits (84), Expect = 0.24
Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 12/78 (15%)
Query: 720 QVNEC-LSNPCIHGNCTGGLSGYKCLCDAGW---------VGINCEVDKNECLSNPCQNG 769
+ EC + + C +G C G+ C C G+ V IN E D+ E S C N
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN-ECDEAEAASPLCVNA 1524
Query: 770 GTCDNLVNGYRCTCKKGF 787
C N +RC C+ GF
Sbjct: 1525 -RCLNTDGSFRCICRPGF 1541
Score = 36.2 bits (82), Expect = 0.41
Identities = 28/88 (31%), Positives = 32/88 (36%), Gaps = 18/88 (20%)
Query: 208 QCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNH 267
+C G TG C CAP T +G PGF C
Sbjct: 44 RCVHGPTGSRCTPT---CAP----RNATSVDSGAPGGAAPGGPGFRAFLCPLI------- 89
Query: 268 RCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
C NGGVCV C CPP + G+FC
Sbjct: 90 -CHNGGVCV---KPDRCLCPPDFAGKFC 113
Score = 36.2 bits (82), Expect = 0.41
Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 15/102 (14%)
Query: 849 KESPNFESYTCLCAPGWQGQRCTIDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGF---- 903
+E P SY A ++ ++ +EC I C N G C + C C G+
Sbjct: 1446 EEPPEGGSYAGSLAEPYE----ELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDM 1500
Query: 904 SGMDCEEDIDDC----LANPCQNGGSCMDGVNTFSCLCLPGF 941
+ M C DI++C A+P C++ +F C+C PGF
Sbjct: 1501 TRMACV-DINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
Score = 35.8 bits (81), Expect = 0.54
Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 29/108 (26%)
Query: 1336 GFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCP-SPRDCESGCASSP------------ 1382
G G R + V C G +CVH +G RC +PR+ S + +P
Sbjct: 26 GRLGERLRVRFTPVVC--GLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRA 83
Query: 1383 ------CQHGGSC-HPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPA 1423
C +GG C P R C C P F+G C+L+++ + PPA
Sbjct: 84 FLCPLICHNGGVCVKPDR------CLCPPDFAGKFCQLHSS-GARPPA 124
Score = 34.7 bits (78), Expect = 1.2
Identities = 52/216 (24%), Positives = 71/216 (32%), Gaps = 48/216 (22%)
Query: 1307 VCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRC 1366
+CP + C NGG C PD C CPP F+G CQ + T S
Sbjct: 85 LCPLI-CHNGGVCV----KPDR--CLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTM 137
Query: 1367 FCPSPRDCESGCASSPCQHGGSCHPQRQPPYY--------SCQCAPPFSGSRCELYTAPP 1418
+ RD E G AS H HPQ + A + +R E
Sbjct: 138 PLANHRDDEHGVASMVSVHVE--HPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAE 195
Query: 1419 STPPATCLSQ---------------YCADKARDGVC----------DEACNSHACQWDGG 1453
+ P T L+Q YC + R G C + C W
Sbjct: 196 AAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVH 255
Query: 1454 DCSLTME---NPWANCSSPLPC---WDYINNQCDEL 1483
DC L E N + PC ++ +N C+++
Sbjct: 256 DCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDV 291
Score = 33.1 bits (74), Expect = 3.5
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 985 ENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCLHEINEC-----SSHPCL 1035
E EC G CV F+C C G+ T C+ +INEC +S C+
Sbjct: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV-DINECDEAEAASPLCV 1522
Query: 1036 NEGTCVDGLGTYRCSCPLGY 1055
N C++ G++RC C G+
Sbjct: 1523 N-ARCLNTDGSFRCICRPGF 1541
Score = 32.3 bits (72), Expect = 5.9
Identities = 25/88 (28%), Positives = 31/88 (35%), Gaps = 17/88 (19%)
Query: 1136 QCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQP 1195
+C G TGS C + GA GG PG++ C
Sbjct: 44 RCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGG------PGFRAFLCPLI-------- 89
Query: 1196 CQNGGTCIDLVNHFKCSCPPGTRGLLCE 1223
C NGG C V +C CPP G C+
Sbjct: 90 CHNGGVC---VKPDRCLCPPDFAGKFCQ 114
Score = 32.0 bits (71), Expect = 7.8
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 9/65 (13%)
Query: 1123 SGVCINAGNTHYCQCPLGY----TGSYCEEQLDEC----ASNPCQHGATCSDFIGGYRCE 1174
+G C+ C+C GY T C + ++EC A++P A C + G +RC
Sbjct: 1478 NGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASPLCVNARCLNTDGSFRCI 1536
Query: 1175 CVPGY 1179
C PG+
Sbjct: 1537 CRPGF 1541
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 255 bits (652), Expect = 3e-67
Identities = 232/819 (28%), Positives = 319/819 (38%), Gaps = 147/819 (17%)
Query: 190 GHCQHG------GTCLNLPGSYQCQCPQGFT----------GQYCDSLYVPCAPSPCVNG 233
G CQ G C++ P Y C C GF C + PCAP C N
Sbjct: 510 GMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENS 569
Query: 234 GTCRQTGDFTFECNCLPGFEGSTCER---NIDDCPNHRCQ---NGGVCVDGVNTYNCRCP 287
+F C C PGF ++D+C HR + G C + ++ C CP
Sbjct: 570 PG-------SFRCVCGPGFRAGPRAAECLDVDEC--HRVPPPCDLGRCENTPGSFLCVCP 620
Query: 288 PQWT----GQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCA 343
+ G C +DVDEC P C G C N G + CVC G+ G C E++D+CA
Sbjct: 621 AGYQAAPHGASC-QDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECA 678
Query: 344 FAS--CTPGSTCIDRVASFSCMCPEG----KAGLLCHLDDACISNP--CHKGALCDTNPL 395
C PG C + SF C CP G G C D C +P C G +T
Sbjct: 679 QEPPPCGPGR-CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTE-- 735
Query: 396 NGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE-CLKGYA- 449
G + C CP G++ G++C EDVDEC + P + +CVN+ G+F C C G+
Sbjct: 736 -GSFQCVCPMGFQPNTAGSEC-EDVDECENHLACPGQ---ECVNSPGSFQCRTCPSGHHL 790
Query: 450 -GPRCEMDINECHSD--PCQNDATCLDKIGGFTCLCMPGFKGVHCE----LEINEC-QSN 501
RC D++EC S PC C + G F C C PG++ ++NEC + +
Sbjct: 791 HRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD 849
Query: 502 PCVNNGQCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQ 557
C +G+C++ F C C PG+ G C +D+D+CS C + +EC
Sbjct: 850 FCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECI 908
Query: 558 CATGFTG----VLCEENIDNC---DPDPCHHGQCQDGIDSYTCI--CNPGYMGAI--CSD 606
C G C + +D C P C +C++ SY C+ C+PGY D
Sbjct: 909 CPPGHRAGPDLASCLD-VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD 967
Query: 607 QIDEC--YSSPCLNDGRCIDLVNGYQCN--CQPG---TSGVNCEINFDDCASNPCI--HG 657
+DEC Y RC + Y+C C PG T G C+ + D+C + H
Sbjct: 968 DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHA 1026
Query: 658 ICMDGINRYSCVCSPGFTGQRCN---IDIDECASNPCRKGATCINGVNG-FRCICPEGPH 713
+C + + C+C G+ G R +D++EC + GA V G F C+CP P
Sbjct: 1027 VCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 1086
Query: 714 HPSCYSQVNECLSNPCIHGNCTGG------------------LSGYKCLCDAGWVGINCE 755
C+ G G L G VG
Sbjct: 1087 EFD--PMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG-- 1142
Query: 756 VDKNECLSNPCQNGGTCDNL----VNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF 811
+ EC + CDN+ V C C G +G+ I +C +
Sbjct: 1143 --RRECYFDTAA-PDACDNILARNVTWQECCCTVG-EGWGSGCRIQQCPGTETAEYQSLC 1198
Query: 812 DDISGYTC---HCVLPYTGKNCQTVL-APCSPNPCENAAVCKESPNFESYTCLCAPGW-- 865
GY L CQ C C N A Y+C C+ G+
Sbjct: 1199 PHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTA--------PGYSCYCSNGYYY 1250
Query: 866 --QGQRCTIDIDECI-SKPCMNHGLCHNTQGSYMCECPP 901
Q C ID DEC +P G C NT GSY C C P
Sbjct: 1251 HTQRLEC-IDNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Score = 253 bits (647), Expect = 1e-66
Identities = 290/1094 (26%), Positives = 428/1094 (39%), Gaps = 183/1094 (16%)
Query: 273 GVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW-- 330
G C G N C EDVDEC CQ+G CAN GGY CVC +G+
Sbjct: 305 GPCPTGFERVNGSC----------EDVDECATG-GRCQHG-ECANTRGGYTCVCPDGFLL 352
Query: 331 --SGDDC-SENIDDCAFASC----TPGSTCIDRVASFS---CMCPE-GKA-GLLCHLDDA 378
S C S+++ A C G + + + + C C GKA G C L
Sbjct: 353 DSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPP 412
Query: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438
S + +C P G + Y ++ ++ S P + G
Sbjct: 413 FGSEGFRE--ICPAGP--GYHYSASDLRYNTRPLGQEPPRVSL--SQPRTLPATSRPSAG 466
Query: 439 AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP--GFKGVHCELEIN 496
L+ PR DP L I +T +P G C+
Sbjct: 467 FLPTHRLEPRPEPR---------PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQ 517
Query: 497 ECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCSST--PCLNGAKCIDH 550
C C++ + + + C C GF G C ID+D+C PC G +C +
Sbjct: 518 VCGPGRCIS------RPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENS 569
Query: 551 PNGYECQCATGF-TGVLCEE--NIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----G 601
P + C C GF G E ++D C P PC G+C++ S+ C+C GY G
Sbjct: 570 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 629
Query: 602 AICSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASN--PCIHGI 658
A C D +DEC SP L G C +L ++C C G G CE + D+CA PC G
Sbjct: 630 ASCQD-VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR 688
Query: 659 CMDGINRYSCVCSPGF----TGQRCNIDIDECASN--PCRKGATCINGVNGFRCICPEGP 712
C + + C C GF G C D+DECA + PC G C N F+C+CP G
Sbjct: 689 CDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYG-RCENTEGSFQCVCPMGF 746
Query: 713 HHPSCYSQ---VNECLSN-PCIHGNCTGGLSGYKC-LCDAG---WVGINCEVDKNECLSN 764
+ S+ V+EC ++ C C ++C C +G G +VD+ +
Sbjct: 747 QPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAP 806
Query: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQ----VNIDECASNP-CLNQGTCFDDISGYTC 819
PC G C N +RC+C G++ + + +++EC C G C + + C
Sbjct: 807 PCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFAC 866
Query: 820 HCVLPY----TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQG---QRCTI 872
C Y G +C V CS + +C + S+ C+C PG + +
Sbjct: 867 TCAPGYRPGPRGASCLDV-DECSEEDLCQSGICTNTDG--SFECICPPGHRAGPDLASCL 923
Query: 873 DIDECISK-PCM-NHGLCHNTQGSYMC--ECPPGF-SGMD--CEEDIDDCLANPCQNGGS 925
D+DEC + P + C N+ GSY C +C PG+ +G + C +D+D+C + G+
Sbjct: 924 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC-DDVDECQEYGPEICGA 982
Query: 926 --CMDGVNTFSC--LCLPGF---TGDKCQTDMNECLSEP-CKNGGTCSDYVNSYTCKCQA 977
C + ++ C C PG+ G CQ D++EC + C C + S+ C C
Sbjct: 983 QRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQ 1041
Query: 978 GF----DGVHCENNINEC-TESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH 1032
G+ DG HC ++NEC T C + SF C+CP
Sbjct: 1042 GYEGARDGRHCV-DVNECETLQGVCGAALCENVEGSFLCVCP------------------ 1082
Query: 1033 PCLNEGTCVDGLGTYRCSCPLGYTG--KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCP 1090
N D + T RC P G Q P + + ++ + P
Sbjct: 1083 ---NSPEEFDPM-TGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGP 1138
Query: 1091 SGWAGAYCDVPNVSCDIAAS--RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEE 1148
G C + D + R V + C G +G QCP T Y
Sbjct: 1139 VGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSG-CRIQQCPGTETAEY--- 1194
Query: 1149 QLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQ---NQPCQNGGTCIDL 1205
+ C HG GY + ++ +VDECQ +Q C++ G C++
Sbjct: 1195 ------QSLCPHGR-------GY----LAPSGDLSLRRDVDECQLFRDQVCKS-GVCVNT 1236
Query: 1206 VNHFKCSCPPG----TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
+ C C G T+ L C +N D+CA GG+C++ +G Y C C P
Sbjct: 1237 APGYSCYCSNGYYYHTQRLECIDN-DECADEEPACEGGRCVNTVGSYHCTCEPPLV---L 1292
Query: 1262 EGDINECLSNPCSS 1275
+G C+SN S
Sbjct: 1293 DGSQRRCVSNESQS 1306
Score = 245 bits (626), Expect = 3e-64
Identities = 236/876 (26%), Positives = 351/876 (40%), Gaps = 189/876 (21%)
Query: 566 LCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDL 625
LC E + N + G C G + C + +DEC + G C +
Sbjct: 289 LCSERLGNSERVSAPDGPCPTGFERVNGSC----------EDVDECATGGRCQHGECANT 338
Query: 626 VNGYQCNCQPG----TSGVNC-EINFDDCASNPCIH----GIC----MDGINRYSCVCSP 672
GY C C G +S +C + A PC G C + I + C CS
Sbjct: 339 RGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSR 398
Query: 673 GFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGP--HHPSCYSQVNE------- 723
G+ C G GFR ICP GP H+ + + N
Sbjct: 399 --VGKAWGRGCQLCPP----------FGSEGFREICPAGPGYHYSASDLRYNTRPLGQEP 446
Query: 724 ---CLSNPCIHGNCTGGLSGY----------------------KCLCDAGWVGINCEVDK 758
LS P + +G+ W G E+ +
Sbjct: 447 PRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTG--PEIPE 504
Query: 759 NECLSNPCQNG------GTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASNPCLNQG 808
+ S CQ G C + +GY C C GF+ G C +++DEC P
Sbjct: 505 SGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVP----- 558
Query: 809 TCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ-G 867
PC+P CEN SP S+ C+C PG++ G
Sbjct: 559 --------------------------PPCAPGRCEN------SPG--SFRCVCGPGFRAG 584
Query: 868 QRCT--IDIDEC--ISKPCMNHGLCHNTQGSYMCECPPGFS----GMDCEEDIDDCLANP 919
R +D+DEC + PC + G C NT GS++C CP G+ G C +D+D+C +P
Sbjct: 585 PRAAECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDECTQSP 642
Query: 920 CQNG-GSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNG-GTCSDYVNSYTCKCQA 977
G G+C + +F C+C GF G C+ D++EC EP G G C + S+ C C A
Sbjct: 643 GLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPA 702
Query: 978 GF----DGVHCENNINECTES--SCFNGGTCVDGINSFSCLCPVGF----TGSFCLHEIN 1027
GF G C+ +++EC S C G C + SF C+CP+GF GS C +++
Sbjct: 703 GFRSRGPGAPCQ-DVDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSEC-EDVD 759
Query: 1028 ECSSHPCLNEGTCVDGLGTYRC-SCPLG-YTGKNCQTLVNLCSRS--PCKNKGTCVQKKA 1083
EC +H CV+ G+++C +CP G + + T V+ CS PC G C +
Sbjct: 760 ECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEG 819
Query: 1084 ESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY-- 1141
+C C G+ A P D+ G C G C+N + C C GY
Sbjct: 820 SFRCSCAPGYR-APSGRPGPCADVNECLEG----DFCFPHGECLNTDGSFACTCAPGYRP 874
Query: 1142 --TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQG----VNCEYEVDECQNQ- 1194
G+ C + +DEC+ C++ G + C C PG++ +C +VDEC+ +
Sbjct: 875 GPRGASCLD-VDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERG 932
Query: 1195 PCQNGG-TCIDLVNHFKC--SCPPGTRG---LLCEENIDDCAR-GPHCLNGGQCMDRIGG 1247
P G C + ++C C PG C++ +D+C GP +C + G
Sbjct: 933 PALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDD-VDECQEYGPEICGAQRCENTPGS 991
Query: 1248 YSC--RCLPGF---AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVC----RSAFTG 1298
Y C C PG+ G C+ D++EC + ++ C L + C+C A G
Sbjct: 992 YRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAV-CQNLPGSFQCLCDQGYEGARDG 1049
Query: 1299 RHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCP 1334
RHC V+ C + + G A+ N+ F+C CP
Sbjct: 1050 RHC-VDVNECETLQGVCG--AALCENVEGSFLCVCP 1082
Score = 241 bits (616), Expect = 5e-63
Identities = 266/969 (27%), Positives = 370/969 (38%), Gaps = 220/969 (22%)
Query: 711 GPHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNEC--L 762
GP P C NP C G C SGY C CD+G+ G C +D +EC +
Sbjct: 499 GPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRV 557
Query: 763 SNPCQNGGTCDNLVNGYRCTCKKGFKG----YNCQVNIDECASNPCLNQGTCFDDISGYT 818
PC G C+N +RC C GF+ C +++DEC
Sbjct: 558 PPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAEC-LDVDEC------------------- 596
Query: 819 CHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDI 874
H V P PC CEN S+ C+C G+Q G C D+
Sbjct: 597 -HRVPP-----------PCDLGRCENTP--------GSFLCVCPAGYQAAPHGASCQ-DV 635
Query: 875 DECISKPCM-NHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNG-GSCMDGVNT 932
DEC P + G C N GS+ C CP GF G CEED+D+C P G G C + +
Sbjct: 636 DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGS 695
Query: 933 FSCLCLPGF----TGDKCQTDMNECL-SEPCKNGGTCSDYVNSYTCKCQAGFD----GVH 983
F C C GF G CQ D++EC S P G C + S+ C C GF G
Sbjct: 696 FHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSE 754
Query: 984 CENNINECTESSCFNGGTCVDGINSFSC-LCPVGFTGSFCLH-----EINECSS--HPCL 1035
CE +++EC G CV+ SF C CP G LH +++ECSS PC
Sbjct: 755 CE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHH----LHRGRCTDVDECSSGAPPCG 809
Query: 1036 NEGTCVDGLGTYRCSCPLGYTGKN-----CQTLVNLCSRSPCKNKGTCVQKKAESQCLCP 1090
G C + G++RCSC GY + C + C G C+ C C
Sbjct: 810 PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 869
Query: 1091 SGW----AGAYC-DVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG-- 1143
G+ GA C DV S E LCQ SG+C N + C CP G+
Sbjct: 870 PGYRPGPRGASCLDVDECS-----------EEDLCQ-SGICTNTDGSFECICPPGHRAGP 917
Query: 1144 --SYCEEQLDECAS-NPCQHGA-TCSDFIGGYRC--ECVPGYQG---VNCEYEVDECQNQ 1194
+ C + +DEC P G+ C + G YRC +C PGY C+ +VDECQ
Sbjct: 918 DLASCLD-VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEY 975
Query: 1195 PCQNGGT--CIDLVNHFKC--SCPPG---TRGLLCEENIDDCARGPHCLNGGQCMDRIGG 1247
+ G C + ++C +C PG T G C++ +D+C C C + G
Sbjct: 976 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQD-VDECRNRSFCGAHAVCQNLPGS 1034
Query: 1248 YSCRCLPGFAGERCEG----DINEC--LSNPCSSEGSLDCIQLTNDYLCVCRSA------ 1295
+ C C G+ G R +G D+NEC L C G+ C + +LCVC ++
Sbjct: 1035 FQCLCDQGYEGAR-DGRHCVDVNECETLQGVC---GAALCENVEGSFLCVCPNSPEEFDP 1090
Query: 1296 FTGR------HCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCP------PGFSGAR-- 1341
TGR TF PQ P + + + P + R P P SG R
Sbjct: 1091 MTGRCVPPRTSAGTFPGSQPQAP----ASPVLPARPPPPPLPRRPSTPRQGPVGSGRREC 1146
Query: 1342 -----CQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPP 1396
+C + R + C C SGC C + Q P
Sbjct: 1147 YFDTAAPDACDNILAR-------NVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCP 1199
Query: 1397 YYSCQCAPP--------------FSGSRCELYTAPPSTPPATCLSQYCAD------KARD 1436
+ AP F C+ + P +C YC++ + +
Sbjct: 1200 HGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC---YCSNGYYYHTQRLE 1256
Query: 1437 GVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDN--- 1493
+ ++ C +GG C T+ + C PL D +C + N + L DN
Sbjct: 1257 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL-VLDGSQRRC--VSNESQSLDDNLGV 1313
Query: 1494 -FECQGNSKTCKYDKYCADHFKDNHCDQGCNSEEC------GWDGLDCAADQPENLAEGT 1546
++ G C + + D+ EC W G+DCA ++ +
Sbjct: 1314 CWQEVGADLVCSHPR----------LDRQATYTECCCLYGEAW-GMDCALCPAQDSDDFE 1362
Query: 1547 LVIVVLMPP 1555
+ VL PP
Sbjct: 1363 ALCNVLRPP 1371
Score = 218 bits (555), Expect = 6e-56
Identities = 234/847 (27%), Positives = 335/847 (39%), Gaps = 140/847 (16%)
Query: 68 CEKNRCQNG-GTCVAQAMLGKATCRCASGFT----GEDCQYSTSHPCFVSRPCLNGGTCH 122
C++N G G C+++ TC C SGF G C V PC G C
Sbjct: 512 CQRNPQVCGPGRCISRP--SGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCE 567
Query: 123 MLSRDTYECTCQVGFTG----KECQWTDAC--LSHPCANGSTCTTVANQFSCKCLTGFT- 175
S ++ C C GF EC D C + PC G C F C C G+
Sbjct: 568 N-SPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQA 625
Query: 176 ---GQKCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCA--PSP 229
G C+ DV+EC PG C G C NLPGS++C CP GF G C+ CA P P
Sbjct: 626 APHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPP 683
Query: 230 CVNGGTCRQTGDFTFECNCLPGFE----GSTCERNIDDCPNH--RCQNGGVCVDGVNTYN 283
C G C T +F C C GF G+ C+ ++D+C C G C + ++
Sbjct: 684 C-GPGRCDNTAG-SFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGR-CENTEGSFQ 739
Query: 284 CRCP----PQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGC-VCVNG--WSGDDCS 336
C CP P G C EDVDEC + + G C N G + C C +G C+
Sbjct: 740 CVCPMGFQPNTAGSEC-EDVDEC--ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCT 796
Query: 337 ENIDDCAFAS--CTPGSTCIDRVASFSCMC------PEGKAGLLCHLDDACISNPCHKGA 388
+ +D+C+ + C P C + SF C C P G+ G +++ + C
Sbjct: 797 D-VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHG 855
Query: 389 LCDTNPLNGQYICTCPQGY----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC 444
C +G + CTC GY +GA C DVDEC + + C+ +G C NTDG+F C C
Sbjct: 856 ECLNT--DGSFACTCAPGYRPGPRGASCL-DVDEC--SEEDLCQ-SGICTNTDGSFECIC 909
Query: 445 LKGY-AGPRCE--MDINEC--HSDPCQNDATCLDKIGGFTCL--CMPGFKG---VHCELE 494
G+ AGP +D++EC C + G + C+ C PG+ C+ +
Sbjct: 910 PPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-D 968
Query: 495 INECQS-NPCVNNGQ-CVDKVNRFQC--LCPPGF---TGPVCQIDIDDCSSTP-CLNGAK 546
++ECQ P + Q C + ++C C PG+ G CQ D+D+C + C A
Sbjct: 969 VDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAV 1027
Query: 547 CIDHPNGYECQCATGFTGVLCEE---NIDNCD--PDPCHHGQCQDGIDSYTCIC------ 595
C + P ++C C G+ G +++ C+ C C++ S+ C+C
Sbjct: 1028 CQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 1087
Query: 596 ---------NPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGV-NCEIN 645
P + +SP L + + G G E
Sbjct: 1088 FDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY 1147
Query: 646 FDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFR 705
FD A + C I + C C+ G G I +C + ++
Sbjct: 1148 FDTAAPDAC-DNILARNVTWQECCCTVG-EGWGSGCRIQQCPGTETAE----------YQ 1195
Query: 706 CICPEGPHH------PSCYSQVNEC---LSNPCIHGNCTGGLSGYKCLCDAGWV----GI 752
+CP G + S V+EC C G C GY C C G+ +
Sbjct: 1196 SLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRL 1255
Query: 753 NCEVDKNECL-SNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCL----NQ 807
C +D +EC P GG C N V Y CTC+ Q C SN N
Sbjct: 1256 EC-IDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQ---RRCVSNESQSLDDNL 1311
Query: 808 GTCFDDI 814
G C+ ++
Sbjct: 1312 GVCWQEV 1318
Score = 162 bits (410), Expect = 4e-39
Identities = 153/517 (29%), Positives = 198/517 (38%), Gaps = 114/517 (22%)
Query: 20 AAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCK---------CPEGFLGEYC-------- 62
AAP H C+D E + G+C G G CK CP GF G C
Sbjct: 625 AAP-HGASCQDVDECTQSPGLC-----GRGACKNLPGSFRCVCPAGFRGSACEEDVDECA 678
Query: 63 QHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGF----TGEDCQYSTSHPCFVSRPCLNG 118
Q PC RC N G C C +GF G CQ C S P
Sbjct: 679 QEPPPCGPGRCDN--------TAGSFHCACPAGFRSRGPGAPCQ--DVDECARSPPPCTY 728
Query: 119 GTCHMLSRDTYECTCQVGF----TGKECQWTDACLSHPCANGSTCTTVANQFSCK-CLTG 173
G C + +++C C +GF G EC+ D C +H G C F C+ C +G
Sbjct: 729 GRCEN-TEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSG 787
Query: 174 --FTGQKCETDVNECDIPG-HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAP-SP 229
+C TDV+EC C G C N GS++C C G+ PCA +
Sbjct: 788 HHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAP--SGRPGPCADVNE 844
Query: 230 CVNGGTCRQTG-----DFTFECNCLPGF----EGSTCERNIDDCPNHRCQNGGVCVDGVN 280
C+ G C G D +F C C PG+ G++C ++D+C G+C +
Sbjct: 845 CLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDG 903
Query: 281 TYNCRCPPQWTG----QFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCS 336
++ C CPP C DVDEC + A C N G Y CV
Sbjct: 904 SFECICPPGHRAGPDLASCL-DVDECRERGPALCGSQRCENSPGSYRCV----------- 951
Query: 337 ENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA-LCDTNPL 395
C PG G G +D+ P GA C+ P
Sbjct: 952 --------RDCDPGYHA-------------GPEGTCDDVDECQEYGPEICGAQRCENTP- 989
Query: 396 NGQYICT--CPQGYK---GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
G Y CT C GY+ G C +DVDEC N + C C N G+F C C +GY G
Sbjct: 990 -GSYRCTPACDPGYQPTPGGGC-QDVDEC--RNRSFCGAHAVCQNLPGSFQCLCDQGYEG 1045
Query: 451 PR----CEMDINECHS-DPCQNDATCLDKIGGFTCLC 482
R C +D+NEC + A C + G F C+C
Sbjct: 1046 ARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVC 1081
Score = 115 bits (288), Expect = 5e-25
Identities = 176/678 (25%), Positives = 255/678 (37%), Gaps = 132/678 (19%)
Query: 923 GGSC---MDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF 979
GG C + G+ T C G +++C + C S+ V++ C GF
Sbjct: 258 GGECASPLPGLRTQEVCC----RGAGLAWGVHDC--QLCSERLGNSERVSAPDGPCPTGF 311
Query: 980 DGVH--CENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCL--HEINECSS 1031
+ V+ CE+ ++EC G C + ++C+CP GF + S C+ H I+E
Sbjct: 312 ERVNGSCED-VDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA-- 368
Query: 1032 HPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSR-SPCKNKG--TCVQKKAES-QC 1087
+G C L CS P+ +N + CSR +G C +E +
Sbjct: 369 -----KGPCFRVLRDGGCSLPI---LRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 420
Query: 1088 LCPSGWAGAYC-------------DVPNVSCD----IAASRR---GVLVEHLCQHSGVCI 1127
+CP+G Y + P VS + A+ R G L H +
Sbjct: 421 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPE-P 479
Query: 1128 NAGNTHYCQCPLGYTGSYCEEQLDEC--ASNPCQHG------ATCSDFIGGYRCECVPGY 1179
+ PL ++ ++ E +S CQ C GY C C G+
Sbjct: 480 RPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGF 539
Query: 1180 ----QGVNCEYEVDECQN--QPCQNGGTCIDLVNHFKCSCPPGTR-GLLCEE--NIDDCA 1230
QG C +VDEC+ PC G C + F+C C PG R G E ++D+C
Sbjct: 540 RLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH 597
Query: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFA----GERCEGDINECLSNPCSSEGSLDCIQLTN 1286
R P + G+C + G + C C G+ G C+ D++EC +P G C L
Sbjct: 598 RVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSP-GLCGRGACKNLPG 655
Query: 1287 DYLCVCRSAFTGRHCETFVDVCPQMPCLNG-GTCAVASNMPDGFICRCPPGF----SGAR 1341
+ CVC + F G CE VD C Q P G G C N F C CP GF GA
Sbjct: 656 SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRC---DNTAGSFHCACPAGFRSRGPGAP 712
Query: 1342 CQ--SSCGQ--VKCRKGEQCVHTASGPRCFCP---SPRDCESGCAS-SPCQHGGSCHPQ- 1392
CQ C + C G +C +T +C CP P S C C++ +C Q
Sbjct: 713 CQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQE 771
Query: 1393 --RQPPYYSCQCAPP---FSGSRCE-----LYTAPPSTP-----------PATCLSQYCA 1431
P + C+ P RC APP P +C Y A
Sbjct: 772 CVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 831
Query: 1432 DKARDGVC---DEACNSHACQWDGGDCSLTMENPWANCSSP--------LPCWDYINNQC 1480
R G C +E C + G+C L + +A +P C D
Sbjct: 832 PSGRPGPCADVNECLEGDFC-FPHGEC-LNTDGSFACTCAPGYRPGPRGASCLDVDECSE 889
Query: 1481 DELCNTVEC--LFDNFEC 1496
++LC + C +FEC
Sbjct: 890 EDLCQSGICTNTDGSFEC 907
Score = 83.6 bits (205), Expect = 2e-15
Identities = 124/481 (25%), Positives = 164/481 (34%), Gaps = 120/481 (24%)
Query: 25 ALQCRDGYEP------------CVNEGMC----VTYHNGTGYCKCPEGFLG--------- 59
A C GY P C E +C T +G+ C CP G
Sbjct: 865 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 924
Query: 60 -EYCQHRDP--CEKNRCQNGG---TCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR 113
+ C+ R P C RC+N CV G + ++CQ C R
Sbjct: 925 VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR 984
Query: 114 PCLNGGTCHMLSRDTYECT--CQVGFT---GKECQWTDACLSHP-CANGSTCTTVANQFS 167
C N + +Y CT C G+ G CQ D C + C + C + F
Sbjct: 985 -CEN-------TPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQ 1036
Query: 168 CKCLTGFTGQK----CETDVNECD-IPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLY 222
C C G+ G + C DVNEC+ + G C C N+ GS+ C CP + + D +
Sbjct: 1037 CLCDQGYEGARDGRHC-VDVNECETLQGVCG-AALCENVEGSFLCVCPN--SPEEFDPMT 1092
Query: 223 VPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTY 282
C P P + GT + LP P
Sbjct: 1093 GRCVP-PRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTP----------------- 1134
Query: 283 NCRCPPQWTGQFCTEDVDECLLQ---PNACQNGGTCANRNGGYGCVCV--NGWSGDDCSE 337
R P +G+ EC P+AC N A C C GW G C
Sbjct: 1135 --RQGPVGSGR------RECYFDTAAPDACDN--ILARNVTWQECCCTVGEGW-GSGC-- 1181
Query: 338 NIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-------DAC---ISNPCHKG 387
I C PG+ A + +CP G+ L D D C C G
Sbjct: 1182 RIQQC------PGT----ETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1231
Query: 388 ALCDTNPLNGQYICTCPQGY----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE 443
+T P Y C C GY + +C D DEC A+ P G+CVNT G++HC
Sbjct: 1232 VCVNTAP---GYSCYCSNGYYYHTQRLECI-DNDEC--ADEEPACEGGRCVNTVGSYHCT 1285
Query: 444 C 444
C
Sbjct: 1286 C 1286
Score = 62.8 bits (151), Expect = 4e-09
Identities = 113/483 (23%), Positives = 170/483 (35%), Gaps = 89/483 (18%)
Query: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
C NGG CV CLCP F G FC +++ + P V GL + PL
Sbjct: 120 CHNGGVCV---KPDRCLCPPDFAGKFC--QLHSSGARP---PAPAVPGLTRSVYTMPLAN 171
Query: 1056 TGKNCQTLVNLCS-RSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGV 1114
+ + ++ S + + V + E W A + +A +
Sbjct: 172 HRDDEHGVASMVSVHVEHPQEASVVVHQVER---VSGPWEEADAEA------VARAEAAA 222
Query: 1115 LVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCE 1174
E ++ + +A G+ YC +L G C+ + G R +
Sbjct: 223 RAEAAAPYTVLAQSAPREDGYSDASGF--GYCFREL---------RGGECASPLPGLRTQ 271
Query: 1175 CVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL--LCEENIDDCARG 1232
V +G + V +CQ + G + + V+ CP G + CE+ +D+CA G
Sbjct: 272 EV-CCRGAGLAWGVHDCQLCSERLGNS--ERVSAPDGPCPTGFERVNGSCED-VDECATG 327
Query: 1233 PHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTND----- 1287
C + G+C + GGY+C C GF + + C+S SE C ++ D
Sbjct: 328 GRCQH-GECANTRGGYTCVCPDGFL---LDSSRSSCISQHVISEAKGPCFRVLRDGGCSL 383
Query: 1288 --------YLCVCR--SAFTGRHC--------ETFVDVCPQMPCLNGGTCAVASN-MPDG 1328
+C C GR C E F ++CP P + + N P G
Sbjct: 384 PILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLG 443
Query: 1329 ----FICRCPPGFSGARCQSSCGQVKCR----KGEQCVHTASGPRCFCPS------PRDC 1374
+ P A + S G + + E GP PS P
Sbjct: 444 QEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIP 503
Query: 1375 ESGCASSPCQHGGS-CHPQR---QPPYYSCQCAPPF----SGSRC----ELYTAPPSTPP 1422
ESG +S CQ C P R +P Y+C C F G+RC E PP P
Sbjct: 504 ESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAP 563
Query: 1423 ATC 1425
C
Sbjct: 564 GRC 566
Score = 52.0 bits (123), Expect = 7e-06
Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 14/104 (13%)
Query: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRC 453
P G Y + + Y+ + +EC + + C + G+CV F C C GY
Sbjct: 1479 PEGGSYAGSLAEPYEELEA----EECGILDG--CTN-GRCVRVPEGFTCRCFDGYRLDMT 1531
Query: 454 EM---DINECH----SDPCQNDATCLDKIGGFTCLCMPGFKGVH 490
M DINEC + P +A CL+ G F C+C PGF H
Sbjct: 1532 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1575
Score = 47.0 bits (110), Expect = 2e-04
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 11/85 (12%)
Query: 449 AGPRCEMDINECHS-DPCQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQ---- 499
A P E++ EC D C N C+ GFTC C G++ + C ++INEC
Sbjct: 1489 AEPYEELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEA 1546
Query: 500 SNPCVNNGQCVDKVNRFQCLCPPGF 524
++P N +C++ F+C+C PGF
Sbjct: 1547 ASPLCVNARCLNTDGSFRCICRPGF 1571
Score = 46.6 bits (109), Expect = 3e-04
Identities = 24/46 (52%), Positives = 25/46 (54%), Gaps = 4/46 (8%)
Query: 170 CLTGF--TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF 213
C TGF CE DV+EC G CQHG C N G Y C CP GF
Sbjct: 307 CPTGFERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 350
Score = 44.3 bits (103), Expect = 0.002
Identities = 27/82 (32%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 153 CANGSTCTTVANQFSCKCLTGF----TGQKCETDVNECDIPGHCQH---GGTCLNLPGSY 205
C NG C V F+C+C G+ T C D+NECD CLN GS+
Sbjct: 1506 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARCLNTDGSF 1563
Query: 206 QCQCPQGFTGQYCDSLYVPCAP 227
+C C GF + P P
Sbjct: 1564 RCICRPGFAPTHQPHHCAPARP 1585
Score = 43.5 bits (101), Expect = 0.003
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 16/87 (18%)
Query: 643 EINFDDCAS-NPCIHGICMDGINRYSCVCSPGF----TGQRCNIDIDEC----ASNPCRK 693
E+ ++C + C +G C+ ++C C G+ T C +DI+EC A++P
Sbjct: 1494 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1552
Query: 694 GATCINGVNGFRCICPEG------PHH 714
A C+N FRCIC G PHH
Sbjct: 1553 NARCLNTDGSFRCICRPGFAPTHQPHH 1579
Score = 43.1 bits (100), Expect = 0.003
Identities = 39/136 (28%), Positives = 57/136 (41%), Gaps = 24/136 (17%)
Query: 507 GQCVDKVNRFQCLCP-PGF-TGPVC------QIDIDDCS-STPCLNGAKCIDHPNGYECQ 557
G C ++ +C P PG T VC + DC + L ++ + P+G
Sbjct: 250 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDG---P 306
Query: 558 CATGFTGV--LCEENIDNCDPDP-CHHGQCQDGIDSYTCICNPGYM-----GAICSDQID 609
C TGF V CE+ +D C C HG+C + YTC+C G++ + S +
Sbjct: 307 CPTGFERVNGSCED-VDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 365
Query: 610 ECYSSPC---LNDGRC 622
PC L DG C
Sbjct: 366 SEAKGPCFRVLRDGGC 381
Score = 43.1 bits (100), Expect = 0.003
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 10/82 (12%)
Query: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDNCDPDP---- 578
P +++ ++C +C+ P G+ C+C G+ T + C + I+ CD
Sbjct: 1491 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASP 1549
Query: 579 -CHHGQCQDGIDSYTCICNPGY 599
C + +C + S+ CIC PG+
Sbjct: 1550 LCVNARCLNTDGSFRCICRPGF 1571
Score = 42.4 bits (98), Expect = 0.006
Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 11/104 (10%)
Query: 808 GTCFDDISGYTCHCVLPYTGKN---CQTVLAPCSPNPCENAAVCKE----SPNFESYTCL 860
G CF ++ G C LP C+ + C+ +C E S +
Sbjct: 250 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQ---LCSERLGNSERVSAPDGP 306
Query: 861 CAPGWQGQRCTI-DIDECISKPCMNHGLCHNTQGSYMCECPPGF 903
C G++ + D+DEC + HG C NT+G Y C CP GF
Sbjct: 307 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGF 350
Score = 41.2 bits (95), Expect = 0.013
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 385 HKGALCDTNPLNGQYICT----CPQGYKGADCT-EDVDECAMANSNPCEHAGKCVNTDGA 439
H LC N + + CP G++ + + EDVDECA C+H G+C NT G
Sbjct: 285 HDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR--CQH-GECANTRGG 341
Query: 440 FHCECLKGY 448
+ C C G+
Sbjct: 342 YTCVCPDGF 350
Score = 41.2 bits (95), Expect = 0.013
Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 10/81 (12%)
Query: 1185 EYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDC----ARGPHCL 1236
E E +EC G C+ + F C C G R + C + I++C A P C+
Sbjct: 1494 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASPLCV 1552
Query: 1237 NGGQCMDRIGGYSCRCLPGFA 1257
N +C++ G + C C PGFA
Sbjct: 1553 NA-RCLNTDGSFRCICRPGFA 1572
Score = 40.8 bits (94), Expect = 0.017
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 7/57 (12%)
Query: 855 ESYTCLCAPGWQ---GQRCTIDIDEC----ISKPCMNHGLCHNTQGSYMCECPPGFS 904
E +TC C G++ + +DI+EC + P + C NT GS+ C C PGF+
Sbjct: 1516 EGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1572
Score = 40.4 bits (93), Expect = 0.022
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 8/76 (10%)
Query: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPG-----TSGVNCEINFDD---CASNPCIHGI 658
+ +EC +GRC+ + G+ C C G T +IN D AS C++
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1555
Query: 659 CMDGINRYSCVCSPGF 674
C++ + C+C PGF
Sbjct: 1556 CLNTDGSFRCICRPGF 1571
Score = 38.9 bits (89), Expect = 0.063
Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 1223 EENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG---DINECLSNPCSSEGSL 1279
E ++C C NG +C+ G++CRC G+ + DINEC +S +
Sbjct: 1494 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1552
Query: 1280 D--CIQLTNDYLCVCRSAFTGRH 1300
+ C+ + C+CR F H
Sbjct: 1553 NARCLNTDGSFRCICRPGFAPTH 1575
Score = 38.9 bits (89), Expect = 0.063
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 15/83 (18%)
Query: 180 ETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC----------APSP 229
E + EC I C +G C+ +P + C+C F G D + C A SP
Sbjct: 1494 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1549
Query: 230 CVNGGTCRQTGDFTFECNCLPGF 252
C T D +F C C PGF
Sbjct: 1550 LCVNARCLNT-DGSFRCICRPGF 1571
Score = 38.1 bits (87), Expect = 0.11
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 20/96 (20%)
Query: 947 QTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCEN------NINECTESS---- 995
+ + EC + + C NG C +TC+C FDG + +INEC E+
Sbjct: 1494 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1549
Query: 996 -CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECS 1030
C N C++ SF C+C GF + H+ + C+
Sbjct: 1550 LCVNA-RCLNTDGSFRCICRPGFAPT---HQPHHCA 1581
Score = 37.0 bits (84), Expect = 0.24
Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 12/78 (15%)
Query: 720 QVNEC-LSNPCIHGNCTGGLSGYKCLCDAGW---------VGINCEVDKNECLSNPCQNG 769
+ EC + + C +G C G+ C C G+ V IN E D+ E S C N
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN-ECDEAEAASPLCVNA 1554
Query: 770 GTCDNLVNGYRCTCKKGF 787
C N +RC C+ GF
Sbjct: 1555 -RCLNTDGSFRCICRPGF 1571
Score = 36.2 bits (82), Expect = 0.41
Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 15/102 (14%)
Query: 849 KESPNFESYTCLCAPGWQGQRCTIDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGF---- 903
+E P SY A ++ ++ +EC I C N G C + C C G+
Sbjct: 1476 EEPPEGGSYAGSLAEPYE----ELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDM 1530
Query: 904 SGMDCEEDIDDC----LANPCQNGGSCMDGVNTFSCLCLPGF 941
+ M C DI++C A+P C++ +F C+C PGF
Sbjct: 1531 TRMACV-DINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1571
Score = 35.0 bits (79), Expect = 0.92
Identities = 14/27 (51%), Positives = 16/27 (59%), Gaps = 3/27 (11%)
Query: 269 CQNGGVCVDGVNTYNCRCPPQWTGQFC 295
C NGGVCV C CPP + G+FC
Sbjct: 120 CHNGGVCV---KPDRCLCPPDFAGKFC 143
Score = 34.7 bits (78), Expect = 1.2
Identities = 52/216 (24%), Positives = 71/216 (32%), Gaps = 48/216 (22%)
Query: 1307 VCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRC 1366
+CP + C NGG C PD C CPP F+G CQ + T S
Sbjct: 115 LCPLI-CHNGGVCV----KPDR--CLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTM 167
Query: 1367 FCPSPRDCESGCASSPCQHGGSCHPQRQPPYY--------SCQCAPPFSGSRCELYTAPP 1418
+ RD E G AS H HPQ + A + +R E
Sbjct: 168 PLANHRDDEHGVASMVSVHVE--HPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAE 225
Query: 1419 STPPATCLSQ---------------YCADKARDGVC----------DEACNSHACQWDGG 1453
+ P T L+Q YC + R G C + C W
Sbjct: 226 AAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVH 285
Query: 1454 DCSLTME---NPWANCSSPLPC---WDYINNQCDEL 1483
DC L E N + PC ++ +N C+++
Sbjct: 286 DCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDV 321
Score = 33.1 bits (74), Expect = 3.5
Identities = 16/29 (55%), Positives = 18/29 (62%), Gaps = 3/29 (10%)
Query: 503 CVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
C N G CV K +R CLCPP F G CQ+
Sbjct: 120 CHNGGVCV-KPDR--CLCPPDFAGKFCQL 145
Score = 33.1 bits (74), Expect = 3.5
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 985 ENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCLHEINEC-----SSHPCL 1035
E EC G CV F+C C G+ T C+ +INEC +S C+
Sbjct: 1494 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV-DINECDEAEAASPLCV 1552
Query: 1036 NEGTCVDGLGTYRCSCPLGY 1055
N C++ G++RC C G+
Sbjct: 1553 N-ARCLNTDGSFRCICRPGF 1571
Score = 32.0 bits (71), Expect = 7.8
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 9/65 (13%)
Query: 1123 SGVCINAGNTHYCQCPLGY----TGSYCEEQLDEC----ASNPCQHGATCSDFIGGYRCE 1174
+G C+ C+C GY T C + ++EC A++P A C + G +RC
Sbjct: 1508 NGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASPLCVNARCLNTDGSFRCI 1566
Query: 1175 CVPGY 1179
C PG+
Sbjct: 1567 CRPGF 1571
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 255 bits (652), Expect = 3e-67
Identities = 232/819 (28%), Positives = 319/819 (38%), Gaps = 147/819 (17%)
Query: 190 GHCQHG------GTCLNLPGSYQCQCPQGFT----------GQYCDSLYVPCAPSPCVNG 233
G CQ G C++ P Y C C GF C + PCAP C N
Sbjct: 547 GMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENS 606
Query: 234 GTCRQTGDFTFECNCLPGFEGSTCER---NIDDCPNHRCQ---NGGVCVDGVNTYNCRCP 287
+F C C PGF ++D+C HR + G C + ++ C CP
Sbjct: 607 PG-------SFRCVCGPGFRAGPRAAECLDVDEC--HRVPPPCDLGRCENTPGSFLCVCP 657
Query: 288 PQWT----GQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCA 343
+ G C +DVDEC P C G C N G + CVC G+ G C E++D+CA
Sbjct: 658 AGYQAAPHGASC-QDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECA 715
Query: 344 FAS--CTPGSTCIDRVASFSCMCPEG----KAGLLCHLDDACISNP--CHKGALCDTNPL 395
C PG C + SF C CP G G C D C +P C G +T
Sbjct: 716 QEPPPCGPGR-CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTE-- 772
Query: 396 NGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE-CLKGYA- 449
G + C CP G++ G++C EDVDEC + P + +CVN+ G+F C C G+
Sbjct: 773 -GSFQCVCPMGFQPNTAGSEC-EDVDECENHLACPGQ---ECVNSPGSFQCRTCPSGHHL 827
Query: 450 -GPRCEMDINECHSD--PCQNDATCLDKIGGFTCLCMPGFKGVHCE----LEINEC-QSN 501
RC D++EC S PC C + G F C C PG++ ++NEC + +
Sbjct: 828 HRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD 886
Query: 502 PCVNNGQCVDKVNRFQCLCPPGFT----GPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQ 557
C +G+C++ F C C PG+ G C +D+D+CS C + +EC
Sbjct: 887 FCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECI 945
Query: 558 CATGFTG----VLCEENIDNC---DPDPCHHGQCQDGIDSYTCI--CNPGYMGAI--CSD 606
C G C + +D C P C +C++ SY C+ C+PGY D
Sbjct: 946 CPPGHRAGPDLASCLD-VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD 1004
Query: 607 QIDEC--YSSPCLNDGRCIDLVNGYQCN--CQPG---TSGVNCEINFDDCASNPCI--HG 657
+DEC Y RC + Y+C C PG T G C+ + D+C + H
Sbjct: 1005 DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHA 1063
Query: 658 ICMDGINRYSCVCSPGFTGQRCN---IDIDECASNPCRKGATCINGVNG-FRCICPEGPH 713
+C + + C+C G+ G R +D++EC + GA V G F C+CP P
Sbjct: 1064 VCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPE 1123
Query: 714 HPSCYSQVNECLSNPCIHGNCTGG------------------LSGYKCLCDAGWVGINCE 755
C+ G G L G VG
Sbjct: 1124 EFD--PMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG-- 1179
Query: 756 VDKNECLSNPCQNGGTCDNL----VNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF 811
+ EC + CDN+ V C C G +G+ I +C +
Sbjct: 1180 --RRECYFDTAA-PDACDNILARNVTWQECCCTVG-EGWGSGCRIQQCPGTETAEYQSLC 1235
Query: 812 DDISGYTC---HCVLPYTGKNCQTVL-APCSPNPCENAAVCKESPNFESYTCLCAPGW-- 865
GY L CQ C C N A Y+C C+ G+
Sbjct: 1236 PHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTA--------PGYSCYCSNGYYY 1287
Query: 866 --QGQRCTIDIDECI-SKPCMNHGLCHNTQGSYMCECPP 901
Q C ID DEC +P G C NT GSY C C P
Sbjct: 1288 HTQRLEC-IDNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Score = 253 bits (647), Expect = 1e-66
Identities = 290/1094 (26%), Positives = 428/1094 (39%), Gaps = 183/1094 (16%)
Query: 273 GVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW-- 330
G C G N C EDVDEC CQ+G CAN GGY CVC +G+
Sbjct: 342 GPCPTGFERVNGSC----------EDVDECATG-GRCQHG-ECANTRGGYTCVCPDGFLL 389
Query: 331 --SGDDC-SENIDDCAFASC----TPGSTCIDRVASFS---CMCPE-GKA-GLLCHLDDA 378
S C S+++ A C G + + + + C C GKA G C L
Sbjct: 390 DSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPP 449
Query: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438
S + +C P G + Y ++ ++ S P + G
Sbjct: 450 FGSEGFRE--ICPAGP--GYHYSASDLRYNTRPLGQEPPRVSL--SQPRTLPATSRPSAG 503
Query: 439 AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP--GFKGVHCELEIN 496
L+ PR DP L I +T +P G C+
Sbjct: 504 FLPTHRLEPRPEPR---------PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQ 554
Query: 497 ECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCSST--PCLNGAKCIDH 550
C C++ + + + C C GF G C ID+D+C PC G +C +
Sbjct: 555 VCGPGRCIS------RPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENS 606
Query: 551 PNGYECQCATGF-TGVLCEE--NIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----G 601
P + C C GF G E ++D C P PC G+C++ S+ C+C GY G
Sbjct: 607 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 666
Query: 602 AICSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASN--PCIHGI 658
A C D +DEC SP L G C +L ++C C G G CE + D+CA PC G
Sbjct: 667 ASCQD-VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR 725
Query: 659 CMDGINRYSCVCSPGF----TGQRCNIDIDECASN--PCRKGATCINGVNGFRCICPEGP 712
C + + C C GF G C D+DECA + PC G C N F+C+CP G
Sbjct: 726 CDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYG-RCENTEGSFQCVCPMGF 783
Query: 713 HHPSCYSQ---VNECLSN-PCIHGNCTGGLSGYKC-LCDAG---WVGINCEVDKNECLSN 764
+ S+ V+EC ++ C C ++C C +G G +VD+ +
Sbjct: 784 QPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAP 843
Query: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQ----VNIDECASNP-CLNQGTCFDDISGYTC 819
PC G C N +RC+C G++ + + +++EC C G C + + C
Sbjct: 844 PCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFAC 903
Query: 820 HCVLPY----TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQG---QRCTI 872
C Y G +C V CS + +C + S+ C+C PG + +
Sbjct: 904 TCAPGYRPGPRGASCLDV-DECSEEDLCQSGICTNTDG--SFECICPPGHRAGPDLASCL 960
Query: 873 DIDECISK-PCM-NHGLCHNTQGSYMC--ECPPGF-SGMD--CEEDIDDCLANPCQNGGS 925
D+DEC + P + C N+ GSY C +C PG+ +G + C +D+D+C + G+
Sbjct: 961 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC-DDVDECQEYGPEICGA 1019
Query: 926 --CMDGVNTFSC--LCLPGF---TGDKCQTDMNECLSEP-CKNGGTCSDYVNSYTCKCQA 977
C + ++ C C PG+ G CQ D++EC + C C + S+ C C
Sbjct: 1020 QRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQ 1078
Query: 978 GF----DGVHCENNINEC-TESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH 1032
G+ DG HC ++NEC T C + SF C+CP
Sbjct: 1079 GYEGARDGRHCV-DVNECETLQGVCGAALCENVEGSFLCVCP------------------ 1119
Query: 1033 PCLNEGTCVDGLGTYRCSCPLGYTG--KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCP 1090
N D + T RC P G Q P + + ++ + P
Sbjct: 1120 ---NSPEEFDPM-TGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGP 1175
Query: 1091 SGWAGAYCDVPNVSCDIAAS--RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEE 1148
G C + D + R V + C G +G QCP T Y
Sbjct: 1176 VGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSG-CRIQQCPGTETAEY--- 1231
Query: 1149 QLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQ---NQPCQNGGTCIDL 1205
+ C HG GY + ++ +VDECQ +Q C++ G C++
Sbjct: 1232 ------QSLCPHGR-------GY----LAPSGDLSLRRDVDECQLFRDQVCKS-GVCVNT 1273
Query: 1206 VNHFKCSCPPG----TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
+ C C G T+ L C +N D+CA GG+C++ +G Y C C P
Sbjct: 1274 APGYSCYCSNGYYYHTQRLECIDN-DECADEEPACEGGRCVNTVGSYHCTCEPPLV---L 1329
Query: 1262 EGDINECLSNPCSS 1275
+G C+SN S
Sbjct: 1330 DGSQRRCVSNESQS 1343
Score = 245 bits (626), Expect = 3e-64
Identities = 236/876 (26%), Positives = 351/876 (40%), Gaps = 189/876 (21%)
Query: 566 LCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDL 625
LC E + N + G C G + C + +DEC + G C +
Sbjct: 326 LCSERLGNSERVSAPDGPCPTGFERVNGSC----------EDVDECATGGRCQHGECANT 375
Query: 626 VNGYQCNCQPG----TSGVNC-EINFDDCASNPCIH----GIC----MDGINRYSCVCSP 672
GY C C G +S +C + A PC G C + I + C CS
Sbjct: 376 RGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSR 435
Query: 673 GFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGP--HHPSCYSQVNE------- 723
G+ C G GFR ICP GP H+ + + N
Sbjct: 436 --VGKAWGRGCQLCPP----------FGSEGFREICPAGPGYHYSASDLRYNTRPLGQEP 483
Query: 724 ---CLSNPCIHGNCTGGLSGY----------------------KCLCDAGWVGINCEVDK 758
LS P + +G+ W G E+ +
Sbjct: 484 PRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTG--PEIPE 541
Query: 759 NECLSNPCQNG------GTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASNPCLNQG 808
+ S CQ G C + +GY C C GF+ G C +++DEC P
Sbjct: 542 SGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVP----- 595
Query: 809 TCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ-G 867
PC+P CEN SP S+ C+C PG++ G
Sbjct: 596 --------------------------PPCAPGRCEN------SPG--SFRCVCGPGFRAG 621
Query: 868 QRCT--IDIDEC--ISKPCMNHGLCHNTQGSYMCECPPGFS----GMDCEEDIDDCLANP 919
R +D+DEC + PC + G C NT GS++C CP G+ G C +D+D+C +P
Sbjct: 622 PRAAECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDECTQSP 679
Query: 920 CQNG-GSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNG-GTCSDYVNSYTCKCQA 977
G G+C + +F C+C GF G C+ D++EC EP G G C + S+ C C A
Sbjct: 680 GLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPA 739
Query: 978 GF----DGVHCENNINECTES--SCFNGGTCVDGINSFSCLCPVGF----TGSFCLHEIN 1027
GF G C+ +++EC S C G C + SF C+CP+GF GS C +++
Sbjct: 740 GFRSRGPGAPCQ-DVDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSEC-EDVD 796
Query: 1028 ECSSHPCLNEGTCVDGLGTYRC-SCPLG-YTGKNCQTLVNLCSRS--PCKNKGTCVQKKA 1083
EC +H CV+ G+++C +CP G + + T V+ CS PC G C +
Sbjct: 797 ECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEG 856
Query: 1084 ESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY-- 1141
+C C G+ A P D+ G C G C+N + C C GY
Sbjct: 857 SFRCSCAPGYR-APSGRPGPCADVNECLEG----DFCFPHGECLNTDGSFACTCAPGYRP 911
Query: 1142 --TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQG----VNCEYEVDECQNQ- 1194
G+ C + +DEC+ C++ G + C C PG++ +C +VDEC+ +
Sbjct: 912 GPRGASCLD-VDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERG 969
Query: 1195 PCQNGG-TCIDLVNHFKC--SCPPGTRG---LLCEENIDDCAR-GPHCLNGGQCMDRIGG 1247
P G C + ++C C PG C++ +D+C GP +C + G
Sbjct: 970 PALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDD-VDECQEYGPEICGAQRCENTPGS 1028
Query: 1248 YSC--RCLPGF---AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVC----RSAFTG 1298
Y C C PG+ G C+ D++EC + ++ C L + C+C A G
Sbjct: 1029 YRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAV-CQNLPGSFQCLCDQGYEGARDG 1086
Query: 1299 RHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCP 1334
RHC V+ C + + G A+ N+ F+C CP
Sbjct: 1087 RHC-VDVNECETLQGVCG--AALCENVEGSFLCVCP 1119
Score = 241 bits (616), Expect = 5e-63
Identities = 266/969 (27%), Positives = 370/969 (38%), Gaps = 220/969 (22%)
Query: 711 GPHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNEC--L 762
GP P C NP C G C SGY C CD+G+ G C +D +EC +
Sbjct: 536 GPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRV 594
Query: 763 SNPCQNGGTCDNLVNGYRCTCKKGFKG----YNCQVNIDECASNPCLNQGTCFDDISGYT 818
PC G C+N +RC C GF+ C +++DEC
Sbjct: 595 PPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAEC-LDVDEC------------------- 633
Query: 819 CHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDI 874
H V P PC CEN S+ C+C G+Q G C D+
Sbjct: 634 -HRVPP-----------PCDLGRCENTP--------GSFLCVCPAGYQAAPHGASCQ-DV 672
Query: 875 DECISKPCM-NHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNG-GSCMDGVNT 932
DEC P + G C N GS+ C CP GF G CEED+D+C P G G C + +
Sbjct: 673 DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGS 732
Query: 933 FSCLCLPGF----TGDKCQTDMNECL-SEPCKNGGTCSDYVNSYTCKCQAGFD----GVH 983
F C C GF G CQ D++EC S P G C + S+ C C GF G
Sbjct: 733 FHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSE 791
Query: 984 CENNINECTESSCFNGGTCVDGINSFSC-LCPVGFTGSFCLH-----EINECSS--HPCL 1035
CE +++EC G CV+ SF C CP G LH +++ECSS PC
Sbjct: 792 CE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHH----LHRGRCTDVDECSSGAPPCG 846
Query: 1036 NEGTCVDGLGTYRCSCPLGYTGKN-----CQTLVNLCSRSPCKNKGTCVQKKAESQCLCP 1090
G C + G++RCSC GY + C + C G C+ C C
Sbjct: 847 PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 906
Query: 1091 SGW----AGAYC-DVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG-- 1143
G+ GA C DV S E LCQ SG+C N + C CP G+
Sbjct: 907 PGYRPGPRGASCLDVDECS-----------EEDLCQ-SGICTNTDGSFECICPPGHRAGP 954
Query: 1144 --SYCEEQLDECAS-NPCQHGA-TCSDFIGGYRC--ECVPGYQG---VNCEYEVDECQNQ 1194
+ C + +DEC P G+ C + G YRC +C PGY C+ +VDECQ
Sbjct: 955 DLASCLD-VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEY 1012
Query: 1195 PCQNGGT--CIDLVNHFKC--SCPPG---TRGLLCEENIDDCARGPHCLNGGQCMDRIGG 1247
+ G C + ++C +C PG T G C++ +D+C C C + G
Sbjct: 1013 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQD-VDECRNRSFCGAHAVCQNLPGS 1071
Query: 1248 YSCRCLPGFAGERCEG----DINEC--LSNPCSSEGSLDCIQLTNDYLCVCRSA------ 1295
+ C C G+ G R +G D+NEC L C G+ C + +LCVC ++
Sbjct: 1072 FQCLCDQGYEGAR-DGRHCVDVNECETLQGVC---GAALCENVEGSFLCVCPNSPEEFDP 1127
Query: 1296 FTGR------HCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCP------PGFSGAR-- 1341
TGR TF PQ P + + + P + R P P SG R
Sbjct: 1128 MTGRCVPPRTSAGTFPGSQPQAP----ASPVLPARPPPPPLPRRPSTPRQGPVGSGRREC 1183
Query: 1342 -----CQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPP 1396
+C + R + C C SGC C + Q P
Sbjct: 1184 YFDTAAPDACDNILAR-------NVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCP 1236
Query: 1397 YYSCQCAPP--------------FSGSRCELYTAPPSTPPATCLSQYCAD------KARD 1436
+ AP F C+ + P +C YC++ + +
Sbjct: 1237 HGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC---YCSNGYYYHTQRLE 1293
Query: 1437 GVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDN--- 1493
+ ++ C +GG C T+ + C PL D +C + N + L DN
Sbjct: 1294 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL-VLDGSQRRC--VSNESQSLDDNLGV 1350
Query: 1494 -FECQGNSKTCKYDKYCADHFKDNHCDQGCNSEEC------GWDGLDCAADQPENLAEGT 1546
++ G C + + D+ EC W G+DCA ++ +
Sbjct: 1351 CWQEVGADLVCSHPR----------LDRQATYTECCCLYGEAW-GMDCALCPAQDSDDFE 1399
Query: 1547 LVIVVLMPP 1555
+ VL PP
Sbjct: 1400 ALCNVLRPP 1408
Score = 218 bits (555), Expect = 6e-56
Identities = 234/847 (27%), Positives = 335/847 (39%), Gaps = 140/847 (16%)
Query: 68 CEKNRCQNG-GTCVAQAMLGKATCRCASGFT----GEDCQYSTSHPCFVSRPCLNGGTCH 122
C++N G G C+++ TC C SGF G C V PC G C
Sbjct: 549 CQRNPQVCGPGRCISRP--SGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCE 604
Query: 123 MLSRDTYECTCQVGFTG----KECQWTDAC--LSHPCANGSTCTTVANQFSCKCLTGFT- 175
S ++ C C GF EC D C + PC G C F C C G+
Sbjct: 605 N-SPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQA 662
Query: 176 ---GQKCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCA--PSP 229
G C+ DV+EC PG C G C NLPGS++C CP GF G C+ CA P P
Sbjct: 663 APHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPP 720
Query: 230 CVNGGTCRQTGDFTFECNCLPGFE----GSTCERNIDDCPNH--RCQNGGVCVDGVNTYN 283
C G C T +F C C GF G+ C+ ++D+C C G C + ++
Sbjct: 721 C-GPGRCDNTAG-SFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGR-CENTEGSFQ 776
Query: 284 CRCP----PQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGC-VCVNG--WSGDDCS 336
C CP P G C EDVDEC + + G C N G + C C +G C+
Sbjct: 777 CVCPMGFQPNTAGSEC-EDVDEC--ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCT 833
Query: 337 ENIDDCAFAS--CTPGSTCIDRVASFSCMC------PEGKAGLLCHLDDACISNPCHKGA 388
+ +D+C+ + C P C + SF C C P G+ G +++ + C
Sbjct: 834 D-VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHG 892
Query: 389 LCDTNPLNGQYICTCPQGY----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC 444
C +G + CTC GY +GA C DVDEC + + C+ +G C NTDG+F C C
Sbjct: 893 ECLNT--DGSFACTCAPGYRPGPRGASCL-DVDEC--SEEDLCQ-SGICTNTDGSFECIC 946
Query: 445 LKGY-AGPRCE--MDINEC--HSDPCQNDATCLDKIGGFTCL--CMPGFKG---VHCELE 494
G+ AGP +D++EC C + G + C+ C PG+ C+ +
Sbjct: 947 PPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-D 1005
Query: 495 INECQS-NPCVNNGQ-CVDKVNRFQC--LCPPGF---TGPVCQIDIDDCSSTP-CLNGAK 546
++ECQ P + Q C + ++C C PG+ G CQ D+D+C + C A
Sbjct: 1006 VDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAV 1064
Query: 547 CIDHPNGYECQCATGFTGVLCEE---NIDNCD--PDPCHHGQCQDGIDSYTCIC------ 595
C + P ++C C G+ G +++ C+ C C++ S+ C+C
Sbjct: 1065 CQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEE 1124
Query: 596 ---------NPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGV-NCEIN 645
P + +SP L + + G G E
Sbjct: 1125 FDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY 1184
Query: 646 FDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFR 705
FD A + C I + C C+ G G I +C + ++
Sbjct: 1185 FDTAAPDAC-DNILARNVTWQECCCTVG-EGWGSGCRIQQCPGTETAE----------YQ 1232
Query: 706 CICPEGPHH------PSCYSQVNEC---LSNPCIHGNCTGGLSGYKCLCDAGWV----GI 752
+CP G + S V+EC C G C GY C C G+ +
Sbjct: 1233 SLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRL 1292
Query: 753 NCEVDKNECL-SNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCL----NQ 807
C +D +EC P GG C N V Y CTC+ Q C SN N
Sbjct: 1293 EC-IDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQ---RRCVSNESQSLDDNL 1348
Query: 808 GTCFDDI 814
G C+ ++
Sbjct: 1349 GVCWQEV 1355
Score = 162 bits (410), Expect = 4e-39
Identities = 153/517 (29%), Positives = 198/517 (38%), Gaps = 114/517 (22%)
Query: 20 AAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCK---------CPEGFLGEYC-------- 62
AAP H C+D E + G+C G G CK CP GF G C
Sbjct: 662 AAP-HGASCQDVDECTQSPGLC-----GRGACKNLPGSFRCVCPAGFRGSACEEDVDECA 715
Query: 63 QHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGF----TGEDCQYSTSHPCFVSRPCLNG 118
Q PC RC N G C C +GF G CQ C S P
Sbjct: 716 QEPPPCGPGRCDN--------TAGSFHCACPAGFRSRGPGAPCQ--DVDECARSPPPCTY 765
Query: 119 GTCHMLSRDTYECTCQVGF----TGKECQWTDACLSHPCANGSTCTTVANQFSCK-CLTG 173
G C + +++C C +GF G EC+ D C +H G C F C+ C +G
Sbjct: 766 GRCEN-TEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSG 824
Query: 174 --FTGQKCETDVNECDIPG-HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAP-SP 229
+C TDV+EC C G C N GS++C C G+ PCA +
Sbjct: 825 HHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAP--SGRPGPCADVNE 881
Query: 230 CVNGGTCRQTG-----DFTFECNCLPGF----EGSTCERNIDDCPNHRCQNGGVCVDGVN 280
C+ G C G D +F C C PG+ G++C ++D+C G+C +
Sbjct: 882 CLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDG 940
Query: 281 TYNCRCPPQWTG----QFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCS 336
++ C CPP C DVDEC + A C N G Y CV
Sbjct: 941 SFECICPPGHRAGPDLASCL-DVDECRERGPALCGSQRCENSPGSYRCV----------- 988
Query: 337 ENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA-LCDTNPL 395
C PG G G +D+ P GA C+ P
Sbjct: 989 --------RDCDPGYHA-------------GPEGTCDDVDECQEYGPEICGAQRCENTP- 1026
Query: 396 NGQYICT--CPQGYK---GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG 450
G Y CT C GY+ G C +DVDEC N + C C N G+F C C +GY G
Sbjct: 1027 -GSYRCTPACDPGYQPTPGGGC-QDVDEC--RNRSFCGAHAVCQNLPGSFQCLCDQGYEG 1082
Query: 451 PR----CEMDINECHS-DPCQNDATCLDKIGGFTCLC 482
R C +D+NEC + A C + G F C+C
Sbjct: 1083 ARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVC 1118
Score = 115 bits (288), Expect = 5e-25
Identities = 176/678 (25%), Positives = 255/678 (37%), Gaps = 132/678 (19%)
Query: 923 GGSC---MDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF 979
GG C + G+ T C G +++C + C S+ V++ C GF
Sbjct: 295 GGECASPLPGLRTQEVCC----RGAGLAWGVHDC--QLCSERLGNSERVSAPDGPCPTGF 348
Query: 980 DGVH--CENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCL--HEINECSS 1031
+ V+ CE+ ++EC G C + ++C+CP GF + S C+ H I+E
Sbjct: 349 ERVNGSCED-VDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA-- 405
Query: 1032 HPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSR-SPCKNKG--TCVQKKAES-QC 1087
+G C L CS P+ +N + CSR +G C +E +
Sbjct: 406 -----KGPCFRVLRDGGCSLPI---LRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 457
Query: 1088 LCPSGWAGAYC-------------DVPNVSCD----IAASRR---GVLVEHLCQHSGVCI 1127
+CP+G Y + P VS + A+ R G L H +
Sbjct: 458 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPE-P 516
Query: 1128 NAGNTHYCQCPLGYTGSYCEEQLDEC--ASNPCQHG------ATCSDFIGGYRCECVPGY 1179
+ PL ++ ++ E +S CQ C GY C C G+
Sbjct: 517 RPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGF 576
Query: 1180 ----QGVNCEYEVDECQN--QPCQNGGTCIDLVNHFKCSCPPGTR-GLLCEE--NIDDCA 1230
QG C +VDEC+ PC G C + F+C C PG R G E ++D+C
Sbjct: 577 RLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH 634
Query: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFA----GERCEGDINECLSNPCSSEGSLDCIQLTN 1286
R P + G+C + G + C C G+ G C+ D++EC +P G C L
Sbjct: 635 RVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSP-GLCGRGACKNLPG 692
Query: 1287 DYLCVCRSAFTGRHCETFVDVCPQMPCLNG-GTCAVASNMPDGFICRCPPGF----SGAR 1341
+ CVC + F G CE VD C Q P G G C N F C CP GF GA
Sbjct: 693 SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRC---DNTAGSFHCACPAGFRSRGPGAP 749
Query: 1342 CQ--SSCGQ--VKCRKGEQCVHTASGPRCFCP---SPRDCESGCAS-SPCQHGGSCHPQ- 1392
CQ C + C G +C +T +C CP P S C C++ +C Q
Sbjct: 750 CQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQE 808
Query: 1393 --RQPPYYSCQCAPP---FSGSRCE-----LYTAPPSTP-----------PATCLSQYCA 1431
P + C+ P RC APP P +C Y A
Sbjct: 809 CVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 868
Query: 1432 DKARDGVC---DEACNSHACQWDGGDCSLTMENPWANCSSP--------LPCWDYINNQC 1480
R G C +E C + G+C L + +A +P C D
Sbjct: 869 PSGRPGPCADVNECLEGDFC-FPHGEC-LNTDGSFACTCAPGYRPGPRGASCLDVDECSE 926
Query: 1481 DELCNTVEC--LFDNFEC 1496
++LC + C +FEC
Sbjct: 927 EDLCQSGICTNTDGSFEC 944
Score = 83.6 bits (205), Expect = 2e-15
Identities = 124/481 (25%), Positives = 164/481 (34%), Gaps = 120/481 (24%)
Query: 25 ALQCRDGYEP------------CVNEGMC----VTYHNGTGYCKCPEGFLG--------- 59
A C GY P C E +C T +G+ C CP G
Sbjct: 902 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 961
Query: 60 -EYCQHRDP--CEKNRCQNGG---TCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR 113
+ C+ R P C RC+N CV G + ++CQ C R
Sbjct: 962 VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR 1021
Query: 114 PCLNGGTCHMLSRDTYECT--CQVGFT---GKECQWTDACLSHP-CANGSTCTTVANQFS 167
C N + +Y CT C G+ G CQ D C + C + C + F
Sbjct: 1022 -CEN-------TPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQ 1073
Query: 168 CKCLTGFTGQK----CETDVNECD-IPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLY 222
C C G+ G + C DVNEC+ + G C C N+ GS+ C CP + + D +
Sbjct: 1074 CLCDQGYEGARDGRHC-VDVNECETLQGVCG-AALCENVEGSFLCVCPN--SPEEFDPMT 1129
Query: 223 VPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTY 282
C P P + GT + LP P
Sbjct: 1130 GRCVP-PRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTP----------------- 1171
Query: 283 NCRCPPQWTGQFCTEDVDECLLQ---PNACQNGGTCANRNGGYGCVCV--NGWSGDDCSE 337
R P +G+ EC P+AC N A C C GW G C
Sbjct: 1172 --RQGPVGSGR------RECYFDTAAPDACDN--ILARNVTWQECCCTVGEGW-GSGC-- 1218
Query: 338 NIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-------DAC---ISNPCHKG 387
I C PG+ A + +CP G+ L D D C C G
Sbjct: 1219 RIQQC------PGT----ETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1268
Query: 388 ALCDTNPLNGQYICTCPQGY----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE 443
+T P Y C C GY + +C D DEC A+ P G+CVNT G++HC
Sbjct: 1269 VCVNTAP---GYSCYCSNGYYYHTQRLECI-DNDEC--ADEEPACEGGRCVNTVGSYHCT 1322
Query: 444 C 444
C
Sbjct: 1323 C 1323
Score = 62.8 bits (151), Expect = 4e-09
Identities = 113/483 (23%), Positives = 170/483 (35%), Gaps = 89/483 (18%)
Query: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
C NGG CV CLCP F G FC +++ + P V GL + PL
Sbjct: 157 CHNGGVCV---KPDRCLCPPDFAGKFC--QLHSSGARP---PAPAVPGLTRSVYTMPLAN 208
Query: 1056 TGKNCQTLVNLCS-RSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGV 1114
+ + ++ S + + V + E W A + +A +
Sbjct: 209 HRDDEHGVASMVSVHVEHPQEASVVVHQVER---VSGPWEEADAEA------VARAEAAA 259
Query: 1115 LVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCE 1174
E ++ + +A G+ YC +L G C+ + G R +
Sbjct: 260 RAEAAAPYTVLAQSAPREDGYSDASGF--GYCFREL---------RGGECASPLPGLRTQ 308
Query: 1175 CVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL--LCEENIDDCARG 1232
V +G + V +CQ + G + + V+ CP G + CE+ +D+CA G
Sbjct: 309 EV-CCRGAGLAWGVHDCQLCSERLGNS--ERVSAPDGPCPTGFERVNGSCED-VDECATG 364
Query: 1233 PHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTND----- 1287
C + G+C + GGY+C C GF + + C+S SE C ++ D
Sbjct: 365 GRCQH-GECANTRGGYTCVCPDGFL---LDSSRSSCISQHVISEAKGPCFRVLRDGGCSL 420
Query: 1288 --------YLCVCR--SAFTGRHC--------ETFVDVCPQMPCLNGGTCAVASN-MPDG 1328
+C C GR C E F ++CP P + + N P G
Sbjct: 421 PILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLG 480
Query: 1329 ----FICRCPPGFSGARCQSSCGQVKCR----KGEQCVHTASGPRCFCPS------PRDC 1374
+ P A + S G + + E GP PS P
Sbjct: 481 QEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIP 540
Query: 1375 ESGCASSPCQHGGS-CHPQR---QPPYYSCQCAPPF----SGSRC----ELYTAPPSTPP 1422
ESG +S CQ C P R +P Y+C C F G+RC E PP P
Sbjct: 541 ESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAP 600
Query: 1423 ATC 1425
C
Sbjct: 601 GRC 603
Score = 52.0 bits (123), Expect = 7e-06
Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 14/104 (13%)
Query: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRC 453
P G Y + + Y+ + +EC + + C + G+CV F C C GY
Sbjct: 1516 PEGGSYAGSLAEPYEELEA----EECGILDG--CTN-GRCVRVPEGFTCRCFDGYRLDMT 1568
Query: 454 EM---DINECH----SDPCQNDATCLDKIGGFTCLCMPGFKGVH 490
M DINEC + P +A CL+ G F C+C PGF H
Sbjct: 1569 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1612
Score = 47.0 bits (110), Expect = 2e-04
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 11/85 (12%)
Query: 449 AGPRCEMDINECHS-DPCQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQ---- 499
A P E++ EC D C N C+ GFTC C G++ + C ++INEC
Sbjct: 1526 AEPYEELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEA 1583
Query: 500 SNPCVNNGQCVDKVNRFQCLCPPGF 524
++P N +C++ F+C+C PGF
Sbjct: 1584 ASPLCVNARCLNTDGSFRCICRPGF 1608
Score = 46.6 bits (109), Expect = 3e-04
Identities = 24/46 (52%), Positives = 25/46 (54%), Gaps = 4/46 (8%)
Query: 170 CLTGF--TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF 213
C TGF CE DV+EC G CQHG C N G Y C CP GF
Sbjct: 344 CPTGFERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 387
Score = 44.3 bits (103), Expect = 0.002
Identities = 27/82 (32%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 153 CANGSTCTTVANQFSCKCLTGF----TGQKCETDVNECDIPGHCQH---GGTCLNLPGSY 205
C NG C V F+C+C G+ T C D+NECD CLN GS+
Sbjct: 1543 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARCLNTDGSF 1600
Query: 206 QCQCPQGFTGQYCDSLYVPCAP 227
+C C GF + P P
Sbjct: 1601 RCICRPGFAPTHQPHHCAPARP 1622
Score = 43.5 bits (101), Expect = 0.003
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 16/87 (18%)
Query: 643 EINFDDCAS-NPCIHGICMDGINRYSCVCSPGF----TGQRCNIDIDEC----ASNPCRK 693
E+ ++C + C +G C+ ++C C G+ T C +DI+EC A++P
Sbjct: 1531 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1589
Query: 694 GATCINGVNGFRCICPEG------PHH 714
A C+N FRCIC G PHH
Sbjct: 1590 NARCLNTDGSFRCICRPGFAPTHQPHH 1616
Score = 43.1 bits (100), Expect = 0.003
Identities = 39/136 (28%), Positives = 57/136 (41%), Gaps = 24/136 (17%)
Query: 507 GQCVDKVNRFQCLCP-PGF-TGPVC------QIDIDDCS-STPCLNGAKCIDHPNGYECQ 557
G C ++ +C P PG T VC + DC + L ++ + P+G
Sbjct: 287 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDG---P 343
Query: 558 CATGFTGV--LCEENIDNCDPDP-CHHGQCQDGIDSYTCICNPGYM-----GAICSDQID 609
C TGF V CE+ +D C C HG+C + YTC+C G++ + S +
Sbjct: 344 CPTGFERVNGSCED-VDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 402
Query: 610 ECYSSPC---LNDGRC 622
PC L DG C
Sbjct: 403 SEAKGPCFRVLRDGGC 418
Score = 43.1 bits (100), Expect = 0.003
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 10/82 (12%)
Query: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDNCDPDP---- 578
P +++ ++C +C+ P G+ C+C G+ T + C + I+ CD
Sbjct: 1528 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASP 1586
Query: 579 -CHHGQCQDGIDSYTCICNPGY 599
C + +C + S+ CIC PG+
Sbjct: 1587 LCVNARCLNTDGSFRCICRPGF 1608
Score = 42.4 bits (98), Expect = 0.006
Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 11/104 (10%)
Query: 808 GTCFDDISGYTCHCVLPYTGKN---CQTVLAPCSPNPCENAAVCKE----SPNFESYTCL 860
G CF ++ G C LP C+ + C+ +C E S +
Sbjct: 287 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQ---LCSERLGNSERVSAPDGP 343
Query: 861 CAPGWQGQRCTI-DIDECISKPCMNHGLCHNTQGSYMCECPPGF 903
C G++ + D+DEC + HG C NT+G Y C CP GF
Sbjct: 344 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGF 387
Score = 41.2 bits (95), Expect = 0.013
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 385 HKGALCDTNPLNGQYICT----CPQGYKGADCT-EDVDECAMANSNPCEHAGKCVNTDGA 439
H LC N + + CP G++ + + EDVDECA C+H G+C NT G
Sbjct: 322 HDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR--CQH-GECANTRGG 378
Query: 440 FHCECLKGY 448
+ C C G+
Sbjct: 379 YTCVCPDGF 387
Score = 41.2 bits (95), Expect = 0.013
Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 10/81 (12%)
Query: 1185 EYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDC----ARGPHCL 1236
E E +EC G C+ + F C C G R + C + I++C A P C+
Sbjct: 1531 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASPLCV 1589
Query: 1237 NGGQCMDRIGGYSCRCLPGFA 1257
N +C++ G + C C PGFA
Sbjct: 1590 NA-RCLNTDGSFRCICRPGFA 1609
Score = 40.8 bits (94), Expect = 0.017
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 7/57 (12%)
Query: 855 ESYTCLCAPGWQ---GQRCTIDIDEC----ISKPCMNHGLCHNTQGSYMCECPPGFS 904
E +TC C G++ + +DI+EC + P + C NT GS+ C C PGF+
Sbjct: 1553 EGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1609
Score = 40.4 bits (93), Expect = 0.022
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 8/76 (10%)
Query: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPG-----TSGVNCEINFDD---CASNPCIHGI 658
+ +EC +GRC+ + G+ C C G T +IN D AS C++
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1592
Query: 659 CMDGINRYSCVCSPGF 674
C++ + C+C PGF
Sbjct: 1593 CLNTDGSFRCICRPGF 1608
Score = 38.9 bits (89), Expect = 0.063
Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 1223 EENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG---DINECLSNPCSSEGSL 1279
E ++C C NG +C+ G++CRC G+ + DINEC +S +
Sbjct: 1531 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1589
Query: 1280 D--CIQLTNDYLCVCRSAFTGRH 1300
+ C+ + C+CR F H
Sbjct: 1590 NARCLNTDGSFRCICRPGFAPTH 1612
Score = 38.9 bits (89), Expect = 0.063
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 15/83 (18%)
Query: 180 ETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC----------APSP 229
E + EC I C +G C+ +P + C+C F G D + C A SP
Sbjct: 1531 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1586
Query: 230 CVNGGTCRQTGDFTFECNCLPGF 252
C T D +F C C PGF
Sbjct: 1587 LCVNARCLNT-DGSFRCICRPGF 1608
Score = 38.1 bits (87), Expect = 0.11
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 20/96 (20%)
Query: 947 QTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCEN------NINECTESS---- 995
+ + EC + + C NG C +TC+C FDG + +INEC E+
Sbjct: 1531 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1586
Query: 996 -CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECS 1030
C N C++ SF C+C GF + H+ + C+
Sbjct: 1587 LCVNA-RCLNTDGSFRCICRPGFAPT---HQPHHCA 1618
Score = 37.0 bits (84), Expect = 0.24
Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 12/78 (15%)
Query: 720 QVNEC-LSNPCIHGNCTGGLSGYKCLCDAGW---------VGINCEVDKNECLSNPCQNG 769
+ EC + + C +G C G+ C C G+ V IN E D+ E S C N
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN-ECDEAEAASPLCVNA 1591
Query: 770 GTCDNLVNGYRCTCKKGF 787
C N +RC C+ GF
Sbjct: 1592 -RCLNTDGSFRCICRPGF 1608
Score = 36.2 bits (82), Expect = 0.41
Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 15/102 (14%)
Query: 849 KESPNFESYTCLCAPGWQGQRCTIDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGF---- 903
+E P SY A ++ ++ +EC I C N G C + C C G+
Sbjct: 1513 EEPPEGGSYAGSLAEPYE----ELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDM 1567
Query: 904 SGMDCEEDIDDC----LANPCQNGGSCMDGVNTFSCLCLPGF 941
+ M C DI++C A+P C++ +F C+C PGF
Sbjct: 1568 TRMACV-DINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1608
Score = 35.0 bits (79), Expect = 0.92
Identities = 14/27 (51%), Positives = 16/27 (59%), Gaps = 3/27 (11%)
Query: 269 CQNGGVCVDGVNTYNCRCPPQWTGQFC 295
C NGGVCV C CPP + G+FC
Sbjct: 157 CHNGGVCV---KPDRCLCPPDFAGKFC 180
Score = 34.7 bits (78), Expect = 1.2
Identities = 52/216 (24%), Positives = 71/216 (32%), Gaps = 48/216 (22%)
Query: 1307 VCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRC 1366
+CP + C NGG C PD C CPP F+G CQ + T S
Sbjct: 152 LCPLI-CHNGGVCV----KPDR--CLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTM 204
Query: 1367 FCPSPRDCESGCASSPCQHGGSCHPQRQPPYY--------SCQCAPPFSGSRCELYTAPP 1418
+ RD E G AS H HPQ + A + +R E
Sbjct: 205 PLANHRDDEHGVASMVSVHVE--HPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAE 262
Query: 1419 STPPATCLSQ---------------YCADKARDGVC----------DEACNSHACQWDGG 1453
+ P T L+Q YC + R G C + C W
Sbjct: 263 AAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVH 322
Query: 1454 DCSLTME---NPWANCSSPLPC---WDYINNQCDEL 1483
DC L E N + PC ++ +N C+++
Sbjct: 323 DCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDV 358
Score = 33.1 bits (74), Expect = 3.5
Identities = 16/29 (55%), Positives = 18/29 (62%), Gaps = 3/29 (10%)
Query: 503 CVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
C N G CV K +R CLCPP F G CQ+
Sbjct: 157 CHNGGVCV-KPDR--CLCPPDFAGKFCQL 182
Score = 33.1 bits (74), Expect = 3.5
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 985 ENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCLHEINEC-----SSHPCL 1035
E EC G CV F+C C G+ T C+ +INEC +S C+
Sbjct: 1531 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV-DINECDEAEAASPLCV 1589
Query: 1036 NEGTCVDGLGTYRCSCPLGY 1055
N C++ G++RC C G+
Sbjct: 1590 N-ARCLNTDGSFRCICRPGF 1608
Score = 32.0 bits (71), Expect = 7.8
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 9/65 (13%)
Query: 1123 SGVCINAGNTHYCQCPLGY----TGSYCEEQLDEC----ASNPCQHGATCSDFIGGYRCE 1174
+G C+ C+C GY T C + ++EC A++P A C + G +RC
Sbjct: 1545 NGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASPLCVNARCLNTDGSFRCI 1603
Query: 1175 CVPGY 1179
C PG+
Sbjct: 1604 CRPGF 1608
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 253 bits (646), Expect = 2e-66
Identities = 125/323 (38%), Positives = 165/323 (51%), Gaps = 19/323 (5%)
Query: 670 CSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLS-NP 728
C PG+TG+ C I C S + C C+C G C NEC+ N
Sbjct: 208 CLPGWTGEYCQQPI--CLSGCHEQNGYCSKPAE---CLCRPGWQGRLC----NECIPHNG 258
Query: 729 CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN-PCQNGGTCDNL-VNGYRCTCKKG 786
C HG C+ + ++C CD GW G+ C+ D N C + PC+NG TC N Y CTC+ G
Sbjct: 259 CRHGTCS---TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPG 315
Query: 787 FKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAA 846
+ G +C++ + EC SNPC N G+C D GY C C Y G +C+ C+ +PC N
Sbjct: 316 YTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGG 375
Query: 847 VCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGM 906
C+E +Y C C P + G C +D C S PC N G C N S MC C PGF+G
Sbjct: 376 SCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGT 435
Query: 907 DCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQ--TDMNECLSEPCKNGGTC 964
CE + DC NPC +GG+C D N C C GF+G +C+ T ++ C S PC N TC
Sbjct: 436 YCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATC 495
Query: 965 SD--YVNSYTCKCQAGFDGVHCE 985
+++ C C GF G CE
Sbjct: 496 YTDLSTDTFVCNCPYGFVGSRCE 518
Score = 250 bits (639), Expect = 1e-65
Identities = 138/385 (35%), Positives = 183/385 (47%), Gaps = 44/385 (11%)
Query: 666 YSCVCSPGFTGQRCNIDI----DECASNPCRKGA--TCINGVNGFRC---ICPEGPHHPS 716
Y +CS + G C+ D C+ +C+ G G C IC G
Sbjct: 171 YRVICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSG----- 225
Query: 717 CYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLV 776
C+ Q C S P +CLC GW G C NEC+ + GTC
Sbjct: 226 CHEQNGYC-SKPA------------ECLCRPGWQGRLC----NECIPHNGCRHGTCST-- 266
Query: 777 NGYRCTCKKGFKGYNCQVNIDECASN-PCLNQGTCFDDIS-GYTCHCVLPYTGKNCQTVL 834
++CTC +G+ G C +++ C + PC N TC + YTC C YTG +C+ L
Sbjct: 267 -PWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELEL 325
Query: 835 APCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCH--NTQ 892
+ C NPC N CK+ + Y CLC PG+ G C C PC N G C N
Sbjct: 326 SECDSNPCRNGGSCKDQE--DGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQG 383
Query: 893 GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNE 952
+Y CECPP F+G +CE+ +D C +NPC NGG C++ + C C PGFTG C+ +++
Sbjct: 384 ANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSD 443
Query: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCE--NNINECTESSCFNGGTCVDGINS-- 1008
C PC +GGTC D N C C AGF G CE +I+ C S CFN TC +++
Sbjct: 444 CARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDT 503
Query: 1009 FSCLCPVGFTGSFCLHEINECSSHP 1033
F C CP GF GS C + S P
Sbjct: 504 FVCNCPYGFVGSRCEFPVGLPPSFP 528
Score = 247 bits (630), Expect = 1e-64
Identities = 134/373 (35%), Positives = 189/373 (50%), Gaps = 30/373 (8%)
Query: 704 FRCICPEGPHHPSCYSQVNECLSNPCIHGNCT--GGLSGYKCLCDAGWVGINCEVDKNEC 761
+R IC + + +C S++ + ++ H C G LS C GW G C+ + C
Sbjct: 171 YRVICSDNYYGDNC-SRLCKKRNDHFGHYVCQPDGNLS-----CLPGWTGEYCQ--QPIC 222
Query: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHC 821
LS + G C C C+ G++G C +EC + GTC + + C C
Sbjct: 223 LSGCHEQNGYCSKPAE---CLCRPGWQGRLC----NECIPHNGCRHGTCS---TPWQCTC 272
Query: 822 VLPYTGKNCQTVLAPCSPN-PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK 880
+ G C L C+ + PC+N A C S SYTC C PG+ G C +++ EC S
Sbjct: 273 DEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQ-RSYTCTCRPGYTGVDCELELSECDSN 331
Query: 881 PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMD---GVNTFSCLC 937
PC N G C + + Y C CPPG+ G+ CE C +PC NGGSC + G N ++C C
Sbjct: 332 PCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGAN-YACEC 390
Query: 938 LPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCF 997
P FTG C+ ++ C S PC NGG C + S C+C+ GF G +CE ++++C + C
Sbjct: 391 PPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCA 450
Query: 998 NGGTCVDGINSFSCLCPVGFTGSFC--LHEINECSSHPCLNEGTCVDGLG--TYRCSCPL 1053
+GGTC D N C CP GF+G C I+ C+S PC N TC L T+ C+CP
Sbjct: 451 HGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPY 510
Query: 1054 GYTGKNCQTLVNL 1066
G+ G C+ V L
Sbjct: 511 GFVGSRCEFPVGL 523
Score = 235 bits (600), Expect = 4e-61
Identities = 125/334 (37%), Positives = 170/334 (50%), Gaps = 31/334 (9%)
Query: 937 CLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSC 996
CLPG+TG+ CQ + CLS + G CS C C+ G+ G C NEC +
Sbjct: 208 CLPGWTGEYCQQPI--CLSGCHEQNGYCSKPAE---CLCRPGWQGRLC----NECIPHNG 258
Query: 997 FNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSH-PCLNEGTCVD-GLGTYRCSCPLG 1054
GTC + C C G+ G FC ++N C+ H PC N TC + G +Y C+C G
Sbjct: 259 CRHGTCS---TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPG 315
Query: 1055 YTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGV 1114
YTG +C+ ++ C +PC+N G+C ++ CLCP G+ G +C+ +SC
Sbjct: 316 YTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSC--------- 366
Query: 1115 LVEHLCQHSGVCI--NAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYR 1172
+ C + G C N G + C+CP +TGS CE+++D C SNPC +G C +
Sbjct: 367 -ADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRM 425
Query: 1173 CECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCE--ENIDDCA 1230
C C PG+ G CE V +C PC +GGTC DL N C+CP G G CE +ID CA
Sbjct: 426 CRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACA 485
Query: 1231 RGPHCLNGGQCMDRIG--GYSCRCLPGFAGERCE 1262
P C N C + + C C GF G RCE
Sbjct: 486 SSP-CFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 235 bits (599), Expect = 5e-61
Identities = 129/382 (33%), Positives = 180/382 (47%), Gaps = 52/382 (13%)
Query: 242 FTFECNCLPGFEGSTCER----NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTE 297
+++ C + G C R D ++ CQ G N C P WTG++C +
Sbjct: 169 YSYRVICSDNYYGDNCSRLCKKRNDHFGHYVCQPDG---------NLSCLPGWTGEYCQQ 219
Query: 298 DVDECLLQPNACQNGGTCANRNGGYG----CVCVNGWSGDDCSENIDDCAFASCTPGSTC 353
+ C +G C +NG C+C GW G C+E C P + C
Sbjct: 220 PI---------CLSG--CHEQNGYCSKPAECLCRPGWQGRLCNE---------CIPHNGC 259
Query: 354 IDRVAS--FSCMCPEGKAGLLCHLD-DACISN-PCHKGALCDTNPLNGQYICTCPQGYKG 409
S + C C EG GL C D + C + PC GA C +N Y CTC GY G
Sbjct: 260 RHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATC-SNSGQRSYTCTCRPGYTG 318
Query: 410 ADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDA 469
DC ++ EC +SNPC + G C + + +HC C GY G CE C PC N
Sbjct: 319 VDCELELSEC---DSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGG 375
Query: 470 TCLDKIGG--FTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGP 527
+C ++ G + C C P F G +CE +++ C SNPC N GQC+++ C C PGFTG
Sbjct: 376 SCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGT 435
Query: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE--ENIDNCDPDPC-HHGQC 584
C++ + DC+ PC +G C D NG C C GF+G CE +ID C PC + C
Sbjct: 436 YCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATC 495
Query: 585 QDGI--DSYTCICNPGYMGAIC 604
+ D++ C C G++G+ C
Sbjct: 496 YTDLSTDTFVCNCPYGFVGSRC 517
Score = 223 bits (569), Expect = 1e-57
Identities = 116/344 (33%), Positives = 164/344 (47%), Gaps = 31/344 (9%)
Query: 203 GSYQCQ------CPQGFTGQYCDSLYVPCAPSPC-VNGGTCRQTGDFTFECNCLPGFEGS 255
G Y CQ C G+TG+YC P S C G C + EC C PG++G
Sbjct: 196 GHYVCQPDGNLSCLPGWTGEYCQQ---PICLSGCHEQNGYCSKPA----ECLCRPGWQGR 248
Query: 256 TCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC 315
C I P++ C++G + C C W G FC +D++ C + C+NG TC
Sbjct: 249 LCNECI---PHNGCRHGTCSTP----WQCTCDEGWGGLFCDQDLNYCT-HHSPCKNGATC 300
Query: 316 ANRNG-GYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLC- 373
+N Y C C G++G DC + +C C G +C D+ + C+CP G GL C
Sbjct: 301 SNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCE 360
Query: 374 HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKC 433
H +C +PC G C Y C CP + G++C + VD C SNPC + G+C
Sbjct: 361 HSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCT---SNPCANGGQC 417
Query: 434 VNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCEL 493
+N + C C G+ G CE+ +++C +PC + TC D G C C GF G CE+
Sbjct: 418 LNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEV 477
Query: 494 E--INECQSNPCVNNGQCVDKVNR--FQCLCPPGFTGPVCQIDI 533
I+ C S+PC N C ++ F C CP GF G C+ +
Sbjct: 478 RTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPV 521
Score = 218 bits (554), Expect = 8e-56
Identities = 122/343 (35%), Positives = 164/343 (47%), Gaps = 39/343 (11%)
Query: 473 DKIGGFTCL------CMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTG 526
D G + C C+PG+ G +C+ I C S NG C +CLC PG+ G
Sbjct: 193 DHFGHYVCQPDGNLSCLPGWTGEYCQQPI--CLSGCHEQNGYCSKPA---ECLCRPGWQG 247
Query: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQD 586
+C I NG + ++C C G+ G+ C+++++ C HH C++
Sbjct: 248 RLCNECIPH-------NGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCT----HHSPCKN 296
Query: 587 GID-------SYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSG 639
G SYTC C PGY G C ++ EC S+PC N G C D +GY C C PG G
Sbjct: 297 GATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYG 356
Query: 640 VNCEINFDDCASNPCIH-GICMD---GINRYSCVCSPGFTGQRCNIDIDECASNPCRKGA 695
++CE + CA +PC + G C + G N Y+C C P FTG C +D C SNPC G
Sbjct: 357 LHCEHSTLSCADSPCFNGGSCRERNQGAN-YACECPPNFTGSNCEKKVDRCTSNPCANGG 415
Query: 696 TCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINC 754
C+N C C G C V++C NPC H G C +G C C AG+ G C
Sbjct: 416 QCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRC 475
Query: 755 EV--DKNECLSNPCQNGGTC--DNLVNGYRCTCKKGFKGYNCQ 793
EV + C S+PC N TC D + + C C GF G C+
Sbjct: 476 EVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 218 bits (554), Expect = 8e-56
Identities = 119/333 (35%), Positives = 168/333 (50%), Gaps = 27/333 (8%)
Query: 49 GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 108
G C G+ GEYCQ + C + G C A C C G+ G C +
Sbjct: 204 GNLSCLPGWTGEYCQ-QPICLSGCHEQNGYCSK-----PAECLCRPGWQGRLC-----NE 252
Query: 109 CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACLSH-PCANGSTCTTVANQ- 165
C C + GTC ++CTC G+ G C Q + C H PC NG+TC+ +
Sbjct: 253 CIPHNGCRH-GTC----STPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRS 307
Query: 166 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC 225
++C C G+TG CE +++ECD C++GG+C + Y C CP G+ G +C+ + C
Sbjct: 308 YTCTCRPGYTGVDCELELSECD-SNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSC 366
Query: 226 APSPCVNGGTCRQTGD-FTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNC 284
A SPC NGG+CR+ + C C P F GS CE+ +D C ++ C NGG C++ + C
Sbjct: 367 ADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMC 426
Query: 285 RCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCS--ENIDDC 342
RC P +TG +C V +C P C +GGTC + G C C G+SG C +ID C
Sbjct: 427 RCRPGFTGTYCELHVSDCARNP--CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDAC 484
Query: 343 AFASCTPGSTCIDRVA--SFSCMCPEGKAGLLC 373
A + C +TC ++ +F C CP G G C
Sbjct: 485 ASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517
Score = 217 bits (553), Expect = 1e-55
Identities = 129/378 (34%), Positives = 177/378 (46%), Gaps = 43/378 (11%)
Query: 92 CASGFTGEDCQYSTSHPCFVSRPCL--NGGTCHMLSRDTYECTCQVGFTGKECQWTDACL 149
C+ + G++C SR C N H + + +C G+TG+ CQ CL
Sbjct: 175 CSDNYYGDNC----------SRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQ-QPICL 223
Query: 150 SHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC 209
S C+ A C C G+ G+ C NEC C+HG TC +QC C
Sbjct: 224 SGCHEQNGYCSKPAE---CLCRPGWQGRLC----NECIPHNGCRHG-TCST---PWQCTC 272
Query: 210 PQGFTGQYCDSLYVPCAP-SPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR 268
+G+ G +CD C SPC NG TC +G ++ C C PG+ G CE + +C ++
Sbjct: 273 DEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNP 332
Query: 269 CQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG--YGCVC 326
C+NGG C D + Y+C CPP + G C C P C NGG+C RN G Y C C
Sbjct: 333 CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSP--CFNGGSCRERNQGANYACEC 390
Query: 327 VNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLC--HLDDACISNPC 384
++G +C + +D C C G C++R S C C G G C H+ D C NPC
Sbjct: 391 PPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSD-CARNPC 449
Query: 385 HKGALCDTNPLNGQYICTCPQGYKGADC--TEDVDECAMANSNPCEHAGKC---VNTDGA 439
G C + L +CTCP G+ G C +D CA S+PC + C ++TD
Sbjct: 450 AHGGTC--HDLENGLMCTCPAGFSGRRCEVRTSIDACA---SSPCFNRATCYTDLSTD-T 503
Query: 440 FHCECLKGYAGPRCEMDI 457
F C C G+ G RCE +
Sbjct: 504 FVCNCPYGFVGSRCEFPV 521
Score = 213 bits (543), Expect = 1e-54
Identities = 131/390 (33%), Positives = 173/390 (44%), Gaps = 45/390 (11%)
Query: 1046 TYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSC 1105
+YR C Y G NC L R+ C + + C GW G YC P
Sbjct: 170 SYRVICSDNYYGDNCSRLCK--KRNDHFGHYVC---QPDGNLSCLPGWTGEYCQQP---- 220
Query: 1106 DIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCS 1165
+ + + +G C C C G+ G C E + N C+HG TCS
Sbjct: 221 --------ICLSGCHEQNGYCSKPAE---CLCRPGWQGRLCNECIPH---NGCRHG-TCS 265
Query: 1166 DFIGGYRCECVPGYQGVNCEYEVDEC-QNQPCQNGGTCIDLVNH-FKCSCPPGTRGLLCE 1223
++C C G+ G+ C+ +++ C + PC+NG TC + + C+C PG G+ CE
Sbjct: 266 T---PWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCE 322
Query: 1224 ENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQ 1283
+ +C P C NGG C D+ GY C C PG+ G CE C +PC + GS
Sbjct: 323 LELSECDSNP-CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERN 381
Query: 1284 LTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
+Y C C FTG +CE VD C PC NGG C N +CRC PGF+G C+
Sbjct: 382 QGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCL---NRGPSRMCRCRPGFTGTYCE 438
Query: 1344 ---SSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCE-----SGCASSPCQHGGSCHPQ 1392
S C + C G C +G C CP S R CE CASSPC + +C+
Sbjct: 439 LHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTD 498
Query: 1393 RQPPYYSCQCAPPFSGSRCELYTA-PPSTP 1421
+ C C F GSRCE PPS P
Sbjct: 499 LSTDTFVCNCPYGFVGSRCEFPVGLPPSFP 528
Score = 213 bits (541), Expect = 2e-54
Identities = 120/358 (33%), Positives = 163/358 (45%), Gaps = 47/358 (13%)
Query: 590 SYTCICNPGYMG----AICSDQIDECYSSPCLNDGRCIDL-------------------V 626
SY IC+ Y G +C + D C DG L
Sbjct: 170 SYRVICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQ 229
Query: 627 NGY-----QCNCQPGTSGVNCEINFDDC-ASNPCIHGICMDGINRYSCVCSPGFTGQRCN 680
NGY +C C+PG G C ++C N C HG C + C C G+ G C+
Sbjct: 230 NGYCSKPAECLCRPGWQGRLC----NECIPHNGCRHGTCS---TPWQCTCDEGWGGLFCD 282
Query: 681 IDIDECA-SNPCRKGATCIN-GVNGFRCICPEGPHHPSCYSQVNECLSNPCIH-GNCTGG 737
D++ C +PC+ GATC N G + C C G C +++EC SNPC + G+C
Sbjct: 283 QDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQ 342
Query: 738 LSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNG--YRCTCKKGFKGYNCQVN 795
GY CLC G+ G++CE C +PC NGG+C G Y C C F G NC+
Sbjct: 343 EDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKK 402
Query: 796 IDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFE 855
+D C SNPC N G C + C C +TG C+ ++ C+ NPC + C + N
Sbjct: 403 VDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLEN-- 460
Query: 856 SYTCLCAPGWQGQRCTI--DIDECISKPCMNHGLCHN--TQGSYMCECPPGFSGMDCE 909
C C G+ G+RC + ID C S PC N C+ + +++C CP GF G CE
Sbjct: 461 GLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 197 bits (502), Expect = 8e-50
Identities = 115/344 (33%), Positives = 164/344 (47%), Gaps = 30/344 (8%)
Query: 170 CLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSP 229
CL G+TG+ C+ + C + G + G C +C C G+ G+ C+ C P
Sbjct: 208 CLPGWTGEYCQQPI--C-LSGCHEQNGYCSK---PAECLCRPGWQGRLCNE----CIPHN 257
Query: 230 CVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR-CQNGGVCVD-GVNTYNCRCP 287
GTC ++C C G+ G C+++++ C +H C+NG C + G +Y C C
Sbjct: 258 GCRHGTCSTP----WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCR 313
Query: 288 PQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASC 347
P +TG C ++ EC N C+NGG+C ++ GY C+C G+ G C + CA + C
Sbjct: 314 PGYTGVDCELELSEC--DSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPC 371
Query: 348 TPGSTCIDRV--ASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCP 404
G +C +R A+++C CP G C D C SNPC G C +C C
Sbjct: 372 FNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNR--GPSRMCRCR 429
Query: 405 QGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEM--DINECHS 462
G+ G C V +CA NPC H G C + + C C G++G RCE+ I+ C S
Sbjct: 430 PGFTGTYCELHVSDCAR---NPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACAS 486
Query: 463 DPCQNDATCLDKIGG--FTCLCMPGFKGVHCELEINECQSNPCV 504
PC N ATC + F C C GF G CE + S P V
Sbjct: 487 SPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLPPSFPWV 530
Score = 165 bits (418), Expect = 4e-40
Identities = 89/233 (38%), Positives = 112/233 (48%), Gaps = 11/233 (4%)
Query: 32 YEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATC 90
+ PC N C + C C G+ G C+ C+ N C+NGG+C Q C
Sbjct: 291 HSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQE--DGYHC 348
Query: 91 RCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRD-TYECTCQVGFTGKECQ-WTDAC 148
C G+ G C++ST PC NGG+C ++ Y C C FTG C+ D C
Sbjct: 349 LCPPGYYGLHCEHSTL--SCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRC 406
Query: 149 LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 208
S+PCANG C C+C GFTG CE V++C C HGGTC +L C
Sbjct: 407 TSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDC-ARNPCAHGGTCHDLENGLMCT 465
Query: 209 CPQGFTGQYCD--SLYVPCAPSPCVNGGTC-RQTGDFTFECNCLPGFEGSTCE 258
CP GF+G+ C+ + CA SPC N TC TF CNC GF GS CE
Sbjct: 466 CPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 140 bits (352), Expect = 2e-32
Identities = 101/368 (27%), Positives = 151/368 (41%), Gaps = 63/368 (17%)
Query: 1153 CASNPCQHGATCS-------DFIGGYRCE------CVPGYQGVNCEYEVDECQNQPCQNG 1199
C+ N +G CS D G Y C+ C+PG+ G C+ + C + +
Sbjct: 175 CSDN--YYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPI--CLSGCHEQN 230
Query: 1200 GTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGE 1259
G C +C C PG +G LC E I PH NG + + C C G+ G
Sbjct: 231 GYCSKPA---ECLCRPGWQGRLCNECI------PH--NGCRHGTCSTPWQCTCDEGWGGL 279
Query: 1260 RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTC 1319
C+ D+N C + G+ Y C CR +TG CE + C PC NGG+C
Sbjct: 280 FCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSC 339
Query: 1320 AVASNMPDGFICRCPPGFSGARCQS---SCGQVKCRKGEQCVHTASGPR--CFCP---SP 1371
+ DG+ C CPPG+ G C+ SC C G C G C CP +
Sbjct: 340 ---KDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTG 396
Query: 1372 RDCE---SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPP------ 1422
+CE C S+PC +GG C + P C+C P F+G+ CEL+ + + P
Sbjct: 397 SNCEKKVDRCTSNPCANGGQC--LNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGT 454
Query: 1423 ---------ATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCW 1473
TC + + + +AC S C ++ C + C+ P +
Sbjct: 455 CHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPC-FNRATCYTDLSTDTFVCNCP---Y 510
Query: 1474 DYINNQCD 1481
++ ++C+
Sbjct: 511 GFVGSRCE 518
Score = 127 bits (318), Expect = 2e-28
Identities = 72/218 (33%), Positives = 100/218 (45%), Gaps = 27/218 (12%)
Query: 23 AHALQCRDGY--------------EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRD-P 67
++ CR GY PC N G C +G +C CP G+ G +C+H
Sbjct: 307 SYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGY-HCLCPPGYYGLHCEHSTLS 365
Query: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSR- 126
C + C NGG+C + C C FTG +C+ S PC NGG C L+R
Sbjct: 366 CADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDR--CTSNPCANGGQC--LNRG 421
Query: 127 DTYECTCQVGFTGKECQ-WTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE--TDV 183
+ C C+ GFTG C+ C +PCA+G TC + N C C GF+G++CE T +
Sbjct: 422 PSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSI 481
Query: 184 NECDIPGHCQHGGTCLN--LPGSYQCQCPQGFTGQYCD 219
+ C C + TC ++ C CP GF G C+
Sbjct: 482 DAC-ASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 92.8 bits (229), Expect = 4e-18
Identities = 44/113 (38%), Positives = 58/113 (51%), Gaps = 5/113 (4%)
Query: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRC 92
PC N G C+ + C+C GF G YC+ H C +N C +GGTC + C C
Sbjct: 410 PCANGGQCLN-RGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTC--HDLENGLMCTC 466
Query: 93 ASGFTGEDCQYSTSHPCFVSRPCLNGGTCHM-LSRDTYECTCQVGFTGKECQW 144
+GF+G C+ TS S PC N TC+ LS DT+ C C GF G C++
Sbjct: 467 PAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEF 519
Score = 57.8 bits (138), Expect = 1e-07
Identities = 31/104 (29%), Positives = 39/104 (37%), Gaps = 18/104 (17%)
Query: 22 PAHALQCRDGY--------------EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR-- 65
P+ +CR G+ PC + G C NG C CP GF G C+ R
Sbjct: 422 PSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGL-MCTCPAGFSGRRCEVRTS 480
Query: 66 -DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 108
D C + C N TC C C GF G C++ P
Sbjct: 481 IDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLP 524
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 253 bits (645), Expect = 2e-66
Identities = 211/721 (29%), Positives = 289/721 (40%), Gaps = 137/721 (19%)
Query: 479 TCLCMPGFKGVHCE--LEINECQSNPCVNNGQCVDKVN------RFQCLCPPGFTGPVCQ 530
TC C PG+ G C + S+P +G C D N R +C+C PG+TGP C
Sbjct: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC- 213
Query: 531 IDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDS 590
C C +C+ C C GF+G C + +C G+C+ G
Sbjct: 214 -GWPSCPG-DCQGRGRCVQG----VCVCRAGFSGPDCSQR--SCPRGCSQRGRCEGG--- 262
Query: 591 YTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCA 650
C+C+PGY G C + C C GRC NG +C C PG +G +C + C
Sbjct: 263 -RCVCDPGYTGDDCG--MRSC-PRGCSQRGRC---ENG-RCVCNPGYTGEDCGVR--SCP 312
Query: 651 SNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPE 710
G C DG CVC PG+TG+ C C +G C++G RC+C
Sbjct: 313 RGCSQRGRCKDG----RCVCDPGYTGEDCG---TRSCPWDCGEGGRCVDG----RCVCWP 361
Query: 711 GPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGG 770
G C ++ C + G C G +C+CD G+ G +C V C G
Sbjct: 362 GYTGEDCSTRT--CPRDCRGRGRCEDG----ECICDTGYSGDDCGV---RSCPGDCNQRG 412
Query: 771 TCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
C++ RC C G+ G +C C +G C + + C C Y+G++C
Sbjct: 413 RCED----GRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV----CVCNAGYSGEDC 461
Query: 831 QTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHN 890
+ C P C C ES C+C PG+ G+ C C G C +
Sbjct: 462 G--VRSC-PGDCRGRGRC------ESGRCMCWPGYTGRDCG---TRACPGDCRGRGRCVD 509
Query: 891 TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM 950
+ C C PGF+G DC C+ G C DGV C+C G++G+ C T
Sbjct: 510 GR----CVCNPGFTGEDCG---SRRCPGDCRGHGLCEDGV----CVCDAGYSGEDCST-- 556
Query: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010
C+ G C D C C+ G+ G C + +C + C G C DG+
Sbjct: 557 -RSCPGGCRGRGQCLD----GRCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDGV---- 604
Query: 1011 CLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRS 1070
C+C G+ C I C S+ C G C +G RC C GYTG C T +C +
Sbjct: 605 CICWEGYVSEDC--SIRTCPSN-CHGRGRCEEG----RCLCDPGYTGPTCAT--RMCP-A 654
Query: 1071 PCKNKGTCVQKKAESQCLCPSGWAGAYC---DVPNVSCDIAASRRGVLVEHLCQHSGVCI 1127
C+ +G CVQ CLC G+ G C + P +C R LC+
Sbjct: 655 DCRGRGRCVQ----GVCLCHVGYGGEDCGQEEPPASACPGGCGPR-----ELCR------ 699
Query: 1128 NAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE 1187
AG C C G+ G C Q C+ C D C C GY G +C E
Sbjct: 700 -AGQ---CVCVEGFRGPDCAIQ---TCPGDCRGRGECHD----GSCVCKDGYAGEDCGEE 748
Query: 1188 V 1188
V
Sbjct: 749 V 749
Score = 251 bits (640), Expect = 8e-66
Identities = 204/726 (28%), Positives = 285/726 (39%), Gaps = 139/726 (19%)
Query: 513 VNRFQCLCPPGFTGPVCQIDID---DCSSTPCLNGAKCIDHPNGY------ECQCATGFT 563
++R C C PG+ GP C D SS P +G+ C D N C C G+T
Sbjct: 151 LSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGS-CPDDCNDQGRCVRGRCVCFPGYT 209
Query: 564 GVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP--CLNDGR 621
G C +C D G+C G+ C+C G+ G CS + S P C GR
Sbjct: 210 GPSC--GWPSCPGDCQGRGRCVQGV----CVCRAGFSGPDCSQR-----SCPRGCSQRGR 258
Query: 622 CIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDG-INRYSCVCSPGFTGQRCN 680
C G +C C PG +G DDC C G G CVC+PG+TG+ C
Sbjct: 259 C----EGGRCVCDPGYTG-------DDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307
Query: 681 IDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSG 740
+ C + C +G RC+C G C ++ C + G C G
Sbjct: 308 V---RSCPRGCSQRGRCKDG----RCVCDPGYTGEDCGTR--SCPWDCGEGGRCVDG--- 355
Query: 741 YKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECA 800
+C+C G+ G +C C+ G C++ C C G+ G +C V C
Sbjct: 356 -RCVCWPGYTGEDC---STRTCPRDCRGRGRCED----GECICDTGYSGDDCGVR--SCP 405
Query: 801 SNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCL 860
+ C +G C D C C YTG +C + P C C E+ C+
Sbjct: 406 GD-CNQRGRCEDG----RCVCWPGYTGTDCG---SRACPRDCRGRGRC------ENGVCV 451
Query: 861 CAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPC 920
C G+ G+ C + C G C S C C PG++G DC C
Sbjct: 452 CNAGYSGEDCGV---RSCPGDCRGRGRCE----SGRCMCWPGYTGRDCG---TRACPGDC 501
Query: 921 QNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD 980
+ G C+DG C+C PGFTG+ C + C + C+ G C D V C C AG+
Sbjct: 502 RGRGRCVDG----RCVCNPGFTGEDCGS--RRCPGD-CRGHGLCEDGV----CVCDAGYS 550
Query: 981 GVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTC 1040
G C C G C+DG C+C G++G C + +C + C G C
Sbjct: 551 GEDCS---TRSCPGGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQC-PNDCSQHGVC 600
Query: 1041 VDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDV 1100
DG+ C C GY ++C + C S C +G C E +CLC G+ G C
Sbjct: 601 QDGV----CICWEGYVSEDCS--IRTCP-SNCHGRGRC----EEGRCLCDPGYTGPTCAT 649
Query: 1101 PNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQH 1160
D C+ G C+ C C +GY G C + +E ++ C
Sbjct: 650 RMCPAD-------------CRGRGRCVQG----VCLCHVGYGGEDCGQ--EEPPASACPG 690
Query: 1161 GATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL 1220
G + +C CV G++G +C + C C+ G C D C C G G
Sbjct: 691 GCGPRELCRAGQCVCVEGFRGPDC--AIQTCPGD-CRGRGECHD----GSCVCKDGYAGE 743
Query: 1221 LCEENI 1226
C E +
Sbjct: 744 DCGEEV 749
Score = 231 bits (589), Expect = 7e-60
Identities = 214/792 (27%), Positives = 293/792 (36%), Gaps = 139/792 (17%)
Query: 518 CLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPD 577
C CPPG PV ++ + + G + QC G + D
Sbjct: 85 CGCPPGTEPPVLASEVQALR----VRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDVR 140
Query: 578 PCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECY--SSPCLNDGRCIDLVNGY------ 629
+ TC C PG+ G CSD D SSP G C D N
Sbjct: 141 TLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRG 200
Query: 630 QCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASN 689
+C C PG +G +C + C + G C+ G+ CVC GF+G +C+
Sbjct: 201 RCVCFPGYTGPSC--GWPSCPGDCQGRGRCVQGV----CVCRAGFSG-------PDCSQR 247
Query: 690 PCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGW 749
C +G + G RC+C G C + C G C G +C+C+ G+
Sbjct: 248 SCPRGCSQRGRCEGGRCVCDPGYTGDDC--GMRSCPRGCSQRGRCENG----RCVCNPGY 301
Query: 750 VGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGT 809
G +C V C G C + RC C G+ G +C C + C G
Sbjct: 302 TGEDCGV---RSCPRGCSQRGRCKD----GRCVCDPGYTGEDCGTR--SCPWD-CGEGGR 351
Query: 810 CFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQR 869
C D C C YTG++C T P C C++ C+C G+ G
Sbjct: 352 CVDG----RCVCWPGYTGEDCST---RTCPRDCRGRGRCEDG------ECICDTGYSGDD 398
Query: 870 CTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDG 929
C + C G C + + C C PG++G DC C+ G C +G
Sbjct: 399 CGV---RSCPGDCNQRGRCEDGR----CVCWPGYTGTDCG---SRACPRDCRGRGRCENG 448
Query: 930 VNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNIN 989
V C+C G++G+ C + C + C+ G C S C C G+ G C
Sbjct: 449 V----CVCNAGYSGEDC--GVRSCPGD-CRGRGRC----ESGRCMCWPGYTGRDCG---T 494
Query: 990 ECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRC 1049
C G CVDG C+C GFTG C C C G C DG+ C
Sbjct: 495 RACPGDCRGRGRCVDG----RCVCNPGFTGEDC--GSRRCPG-DCRGHGLCEDGV----C 543
Query: 1050 SCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAA 1109
C GY+G++C T C C+ +G C+ + +C+C G++G C V C
Sbjct: 544 VCDAGYSGEDCST--RSCP-GGCRGRGQCL----DGRCVCEDGYSGEDCGVR--QCPNDC 594
Query: 1110 SRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIG 1169
S+ GV CQ GVCI C GY C + C SN C C +
Sbjct: 595 SQHGV-----CQ-DGVCI---------CWEGYVSEDC--SIRTCPSN-CHGRGRCEE--- 633
Query: 1170 GYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDC 1229
RC C PGY G C + C+ G C+ V C C G G C +
Sbjct: 634 -GRCLCDPGYTGPTCATRMCPAD---CRGRGRCVQGV----CLCHVGYGGEDCGQEEPPA 685
Query: 1230 ARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYL 1289
+ C G + C C+ GF G C I C P G +C +D
Sbjct: 686 SA---CPGGCGPRELCRAGQCVCVEGFRGPDCA--IQTC---PGDCRGRGEC----HDGS 733
Query: 1290 CVCRSAFTGRHC 1301
CVC+ + G C
Sbjct: 734 CVCKDGYAGEDC 745
Score = 230 bits (587), Expect = 1e-59
Identities = 205/705 (29%), Positives = 270/705 (38%), Gaps = 145/705 (20%)
Query: 85 LGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRD-----TYECTCQVGFTG 139
L + TC C G+ G C T S P G+C D C C G+TG
Sbjct: 151 LSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTG 210
Query: 140 KECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKC--ETDVNECDIPGHCQHGGT 197
C W C C Q C C GF+G C + C G C+ GG
Sbjct: 211 PSCGWPSC--PGDCQGRGRCV----QGVCVCRAGFSGPDCSQRSCPRGCSQRGRCE-GGR 263
Query: 198 CLNLPG----------------------SYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGT 235
C+ PG + +C C G+TG+ C V P C G
Sbjct: 264 CVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG---VRSCPRGCSQRGR 320
Query: 236 CRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
C+ C C PG+ G C CP C GG CVDG C C P +TG+ C
Sbjct: 321 CKDG-----RCVCDPGYTGEDC--GTRSCP-WDCGEGGRCVDG----RCVCWPGYTGEDC 368
Query: 296 TEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID 355
+ C P C+ G C + C+C G+SGDDC + C C C D
Sbjct: 369 S--TRTC---PRDCRGRGRCEDGE----CICDTGYSGDDC--GVRSCP-GDCNQRGRCED 416
Query: 356 RVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTED 415
C+C G G C AC C C+ NG +C C GY G DC
Sbjct: 417 G----RCVCWPGYTGTDCG-SRAC-PRDCRGRGRCE----NG--VCVCNAGYSGEDC--G 462
Query: 416 VDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKI 475
V C C G+C + C C GY G C C D C+ C+D
Sbjct: 463 VRSC----PGDCRGRGRCESG----RCMCWPGYTGRDC--GTRACPGD-CRGRGRCVDG- 510
Query: 476 GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDD 535
C+C PGF G C C + C +G C D V C+C G++G +D
Sbjct: 511 ---RCVCNPGFTGEDC--GSRRCPGD-CRGHGLCEDGV----CVCDAGYSG-------ED 553
Query: 536 CSSTPCLNGAK----CIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSY 591
CS+ C G + C+D C C G++G C + C D HG CQDG+
Sbjct: 554 CSTRSCPGGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQCPNDCSQHGVCQDGV--- 604
Query: 592 TCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCAS 651
CIC GY+ CS I C S+ C GRC + +C C PG +G C C +
Sbjct: 605 -CICWEGYVSEDCS--IRTCPSN-CHGRGRCEE----GRCLCDPGYTGPTCATRM--CPA 654
Query: 652 NPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNP--CRKGATCINGVNGFRCICP 709
+ G C+ G+ C+C G+ G+ C + ++ P C C G +C+C
Sbjct: 655 DCRGRGRCVQGV----CLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG----QCVCV 706
Query: 710 EGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINC 754
EG P C + C + G C G C+C G+ G +C
Sbjct: 707 EGFRGPDC--AIQTCPGDCRGRGECHDG----SCVCKDGYAGEDC 745
Score = 205 bits (522), Expect = 4e-52
Identities = 178/627 (28%), Positives = 230/627 (36%), Gaps = 152/627 (24%)
Query: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
C G CV G C C GF G C R C + C G C C C
Sbjct: 222 CQGRGRCVQ-----GVCVCRAGFSGPDCSQRS-CPRG-CSQRGRCEG------GRCVCDP 268
Query: 95 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154
G+TG+DC + R C G C + C C G+TG++C C
Sbjct: 269 GYTGDDCGMRSC-----PRGCSQRGRC-----ENGRCVCNPGYTGEDCG------VRSCP 312
Query: 155 NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214
G + C C G+TG+ C T C P C GG C++ +C C G+T
Sbjct: 313 RGCSQRGRCKDGRCVCDPGYTGEDCGT--RSC--PWDCGEGGRCVD----GRCVCWPGYT 364
Query: 215 GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGV 274
G+ C + P C G C EC C G+ G C + CP C G
Sbjct: 365 GEDCSTR---TCPRDCRGRGRCEDG-----ECICDTGYSGDDC--GVRSCPGD-CNQRGR 413
Query: 275 CVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDD 334
C DG C C P +TG C C P C+ G C N CVC G+SG+D
Sbjct: 414 CEDG----RCVCWPGYTGTDCGSRA--C---PRDCRGRGRCENGV----CVCNAGYSGED 460
Query: 335 CSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCH--------------LDDACI 380
C SC R S CMC G G C +D C+
Sbjct: 461 CGVR-------SCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCV 513
Query: 381 SNPCHKGALCDTNPLNGQY---------ICTCPQGYKGADCTEDVDECAMANSNPCEHAG 431
NP G C + G +C C GY G DC+ + C G
Sbjct: 514 CNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCS------TRSCPGGCRGRG 567
Query: 432 KCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHC 491
+C+ DG C C GY+G C + +C +D C C D + C+C G+ C
Sbjct: 568 QCL--DG--RCVCEDGYSGEDC--GVRQCPND-CSQHGVCQDGV----CICWEGYVSEDC 616
Query: 492 ELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDI--DDCSST-PCLNGAKCI 548
I C SN C G+C + +CLC PG+TGP C + DC C+ G C+
Sbjct: 617 S--IRTCPSN-CHGRGRCEEG----RCLCDPGYTGPTCATRMCPADCRGRGRCVQGV-CL 668
Query: 549 DH------------------PNGY---------ECQCATGFTGVLCEENIDNCDPDPCHH 581
H P G +C C GF G C I C D
Sbjct: 669 CHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCA--IQTCPGDCRGR 726
Query: 582 GQCQDGIDSYTCICNPGYMGAICSDQI 608
G+C DG +C+C GY G C +++
Sbjct: 727 GECHDG----SCVCKDGYAGEDCGEEV 749
Score = 204 bits (520), Expect = 7e-52
Identities = 209/814 (25%), Positives = 283/814 (34%), Gaps = 163/814 (20%)
Query: 706 CICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC-LSN 764
C CP G P S+V I GL K C G + + + +
Sbjct: 85 CGCPPGTEPPVLASEVQALRVRLEILEELVKGL---KEQCTGGCCPASAQAGTGQTDVRT 141
Query: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDE--CASNPCLNQGTCFDDISGY----- 817
C G D ++ C+C+ G+ G C D S+P G+C DD +
Sbjct: 142 LCSLHGVFD--LSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVR 199
Query: 818 -TCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDE 876
C C YTG +C P P C+ C + C+C G+ G C+
Sbjct: 200 GRCVCFPGYTGPSCGW---PSCPGDCQGRGRCVQG------VCVCRAGFSGPDCS---QR 247
Query: 877 CISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
+ C G C + C C PG++G DC + C C G C +G C+
Sbjct: 248 SCPRGCSQRGRCEGGR----CVCDPGYTGDDC--GMRSC-PRGCSQRGRCENG----RCV 296
Query: 937 CLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSC 996
C PG+TG+ C + C C G C D C C G+ G C C C
Sbjct: 297 CNPGYTGEDC--GVRSC-PRGCSQRGRCKD----GRCVCDPGYTGEDC--GTRSC-PWDC 346
Query: 997 FNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYT 1056
GG CVDG C+C G+TG C C G C DG C C GY+
Sbjct: 347 GEGGRCVDG----RCVCWPGYTGEDC---STRTCPRDCRGRGRCEDG----ECICDTGYS 395
Query: 1057 GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV 1116
G +C V C C +G C + +C+C G+ G C D
Sbjct: 396 GDDCG--VRSCP-GDCNQRGRC----EDGRCVCWPGYTGTDCGSRACPRD---------- 438
Query: 1117 EHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV 1176
C+ G C N C C GY+G C + C + C+ C RC C
Sbjct: 439 ---CRGRGRCENG----VCVCNAGYSGEDC--GVRSCPGD-CRGRGRCE----SGRCMCW 484
Query: 1177 PGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL---------------L 1221
PGY G +C C C+ G C+D +C C PG G L
Sbjct: 485 PGYTGRDCGTRA--CPGD-CRGRGRCVD----GRCVCNPGFTGEDCGSRRCPGDCRGHGL 537
Query: 1222 CEENIDDCARG------------PHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECL 1269
CE+ + C G C GQC+D C C G++GE C + +C
Sbjct: 538 CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQC- 590
Query: 1270 SNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGF 1329
N CS G + D +C+C + C + CP C G C
Sbjct: 591 PNDCSQHG------VCQDGVCICWEGYVSEDCS--IRTCPS-NCHGRGRCEEGR------ 635
Query: 1330 ICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCP---SPRDC-ESGCASSPCQH 1385
C C PG++G C + CR +CV C C DC + +S C
Sbjct: 636 -CLCDPGYTGPTCATRMCPADCRGRGRCVQGV----CLCHVGYGGEDCGQEEPPASACP- 689
Query: 1386 GGSCHPQRQPPYYSCQCAPPFSGSRCELYTAP-PSTPPATCLSQYCADKARDGVCDEACN 1444
G C P+ C C F G C + T P C C +DG E C
Sbjct: 690 -GGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCV--CKDGYAGEDCG 746
Query: 1445 SHACQWDGGDCSL----TMENPWANCSSPLPCWD 1474
+G L T+ W P+ ++
Sbjct: 747 EEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYE 780
Score = 173 bits (439), Expect = 2e-42
Identities = 183/672 (27%), Positives = 243/672 (36%), Gaps = 145/672 (21%)
Query: 882 CMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCL--ANPCQNGGSCMDGVNTFS----- 934
C HG+ ++ + C C PG+ G C + D + ++P GSC D N
Sbjct: 143 CSLHGVFDLSRCT--CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRG 200
Query: 935 -CLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTE 993
C+C PG+TG C C + C+ G C V C C+AGF G C C
Sbjct: 201 RCVCFPGYTGPSC--GWPSCPGD-CQGRGRCVQGV----CVCRAGFSGPDCSQR--SCPR 251
Query: 994 SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPL 1053
C G C G C+C G+TG C + C C G C +G RC C
Sbjct: 252 G-CSQRGRCEGG----RCVCDPGYTGDDC--GMRSCP-RGCSQRGRCENG----RCVCNP 299
Query: 1054 GYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRG 1113
GYTG++C V C R C +G C + +C+C G+ G C + D
Sbjct: 300 GYTGEDCG--VRSCPRG-CSQRGRC----KDGRCVCDPGYTGEDCGTRSCPWD------- 345
Query: 1114 VLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC 1173
C G C++ C C GYTG C + C+ C D C
Sbjct: 346 ------CGEGGRCVDGR----CVCWPGYTGEDCSTRT---CPRDCRGRGRCEDG----EC 388
Query: 1174 ECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP 1233
C GY G +C V C C G C D +C C PG G C C R
Sbjct: 389 ICDTGYSGDDCG--VRSCPGD-CNQRGRCED----GRCVCWPGYTGTDCGSRA--CPRD- 438
Query: 1234 HCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCR 1293
C G+C + + C C G++GE C + C + C G + + C+C
Sbjct: 439 -CRGRGRCENGV----CVCNAGYSGEDC--GVRSCPGD-CRGRGRCESGR------CMCW 484
Query: 1294 SAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRK 1353
+TGR C T CP G C DG C C PGF+G C S CR
Sbjct: 485 PGYTGRDCGT--RACP-------GDCRGRGRCVDGR-CVCNPGFTGEDCGSRRCPGDCRG 534
Query: 1354 GEQCVHTASGPRCFCP---SPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSR 1410
C C C S DC + C+ G C R C C +SG
Sbjct: 535 HGLCEDGV----CVCDAGYSGEDCSTRSCPGGCRGRGQCLDGR------CVCEDGYSGED 584
Query: 1411 CELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDG---GDCSLTMENPWANCS 1467
C + P D ++ GVC + W+G DCS+ +
Sbjct: 585 CGVRQCPN-------------DCSQHGVCQDGV---CICWEGYVSEDCSIR--------T 620
Query: 1468 SPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEEC 1527
P C + +C+E CL D TC AD C QG
Sbjct: 621 CPSNC--HGRGRCEE----GRCLCDPGY---TGPTCATRMCPADCRGRGRCVQGVCLCHV 671
Query: 1528 GWDGLDCAADQP 1539
G+ G DC ++P
Sbjct: 672 GYGGEDCGQEEP 683
Score = 40.4 bits (93), Expect = 0.022
Identities = 59/246 (23%), Positives = 78/246 (31%), Gaps = 52/246 (21%)
Query: 1324 NMPDGFICRCPPGFSGARCQSSCGQVKCR--------KG--EQCVHTASGPRCFCPSPRD 1373
N+P C CPPG S ++ R KG EQC +G C P
Sbjct: 78 NLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQC----TGGCC----PAS 129
Query: 1374 CESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT---APPSTPPATCLSQYC 1430
++G + + S H +C C P + G C T PPS+PP+ S C
Sbjct: 130 AQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSA--SGSC 187
Query: 1431 ADKARDG--------VCDEACNSHACQWDG--GDCS--LTMENPWANCSSPLPCWDYINN 1478
D D VC +C W GDC C + D
Sbjct: 188 PDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQR 247
Query: 1479 QCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSE-EC---------G 1528
C C+ C+G C Y D C +GC+ C G
Sbjct: 248 SCPRGCS------QRGRCEGGRCVCD-PGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPG 300
Query: 1529 WDGLDC 1534
+ G DC
Sbjct: 301 YTGEDC 306
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 233 bits (593), Expect = 2e-60
Identities = 241/854 (28%), Positives = 353/854 (41%), Gaps = 162/854 (18%)
Query: 494 EINECQSNPCV-NNGQCVDKVNRFQCLCPPGFTGPVCQ---IDIDDCSSTPCL-NGAKCI 548
EINEC NP + G C++ R+ C+C G+ Q +DID+C+ L + +C
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 933
Query: 549 DHPNGYECQCATGFT----GVLCEENIDNC-DPDPCHHGQCQDGIDSYTC-ICNPGY--- 599
+ + C C GF G C + +D C PD C G C + + ++ C C+ GY
Sbjct: 934 NTEGSFLCICPAGFMASEEGTNCID-VDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 992
Query: 600 MGAICSDQIDECYSSPCLNDGRCIDLVNGYQC-NCQPGTSGVNCE-INFDDCAS-NPCIH 656
C D IDEC + D +C++ YQC C G G N + ++ D+C N C +
Sbjct: 993 QRGRCED-IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCAN 1051
Query: 657 GICMDGINRYSCVCSPGFTG----QRCNIDIDECASNPCRKGATCINGVNGFRCICPEGP 712
G C + Y C C G+T + C DIDEC C N FRC C +G
Sbjct: 1052 GDCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQCKNTEGSFRCTCGQGY 1110
Query: 713 HHPSCYSQ---VNECLSNP-CIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNECLSN 764
+ Q ++EC C HG C ++C+CD G+ +G +CE D NECL +
Sbjct: 1111 QLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE-DINECLED 1169
Query: 765 P--CQNGGTCDNLVNGYRCTCKKGFK---GYNCQVNIDECAS-NPCLNQGTCFDDISGYT 818
CQ G C N Y CTC GF+ CQ +I+EC C QG C + +
Sbjct: 1170 KSVCQRGD-CINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECLNTEGSFH 1227
Query: 819 CHCVLPYT----GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRC 870
C C ++ G+ C+ + + C++ C + S+ CLC G+Q GQ C
Sbjct: 1228 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAG--SFRCLCYQGFQAPQDGQGC 1285
Query: 871 TIDIDEC--ISKPCMNHGLCHNTQGSYMCECPPG---FSGM----------DCEEDID-- 913
+D++EC +S C C N +GS++C C +S M D + D+D
Sbjct: 1286 -VDVNECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQP 1343
Query: 914 -----DCLANP--------------------CQNGGSCMDGVNTFSCLCL---------- 938
+C N C +G D F C L
Sbjct: 1344 KEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCP 1403
Query: 939 --PGFT---------GDKCQTDMNECL---SEPCKNGGTCSDYVNSYTCKCQAG--FDGV 982
GF G + D +ECL E CKNG C + Y C C+ G +D V
Sbjct: 1404 KGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQGTYYDPV 1462
Query: 983 HCEN-NINECTESSCFNGGTCVDGINSFSCLC--PVGFTGSF--CLH--EINECSSHPCL 1035
+ +++EC + S G CV+ S++C C P+ S C+ E NE +
Sbjct: 1463 KLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDV 1522
Query: 1036 NEGTCVDGLGT-YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES-QC-LCPSG 1092
+ C + L Y CS PL GK QT C C+ +A QC LCP
Sbjct: 1523 YQDLCWEHLSDEYVCSRPL--VGK--QTTYTECC---------CLYGEAWGMQCALCPLK 1569
Query: 1093 WAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDE 1152
+ Y + N+ + R+ + L S + ++ Q + S+ E Q +E
Sbjct: 1570 DSDDYAQLCNIP--VTGRRQPYGRDALVDFSEQYTPEADPYFIQDR--FLNSFEELQAEE 1625
Query: 1153 CAS-NPCQHGATCSDFIGGYRCECVPGYQ----GVNCEYEVDECQN-----QPCQNGGTC 1202
C N C++G C GY C+C GY + C +V+EC C+N C
Sbjct: 1626 CGILNGCENGR-CVRVQEGYTCDCFDGYHLDTAKMTC-VDVNECDELNNRMSLCKN-AKC 1682
Query: 1203 IDLVNHFKCSCPPG 1216
I+ +KC C PG
Sbjct: 1683 INTDGSYKCLCLPG 1696
Score = 228 bits (582), Expect = 4e-59
Identities = 237/866 (27%), Positives = 348/866 (40%), Gaps = 146/866 (16%)
Query: 181 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTC 236
T++NEC + G C+NLP Y C C +G+ + C + + G C
Sbjct: 873 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 932
Query: 237 RQTGDFTFECNCLPGF----EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCR-CPP--Q 289
T + +F C C GF EG+ C ++D+C G CV+ V + C C +
Sbjct: 933 ENT-EGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYR 990
Query: 290 WTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCV-CVNGWSG--DDCSENIDDCAFAS 346
T + ED+DEC L P+ C + C N G Y CV C G+ G C + +D+C +
Sbjct: 991 MTQRGRCEDIDEC-LNPSTCPD-EQCVNSPGSYQCVPCTEGFRGWNGQCLD-VDECLEPN 1047
Query: 347 CTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALC---DTNPLNGQYICTC 403
C + S+ C C +G H I + C +G LC G + CTC
Sbjct: 1048 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDI-DECQQGNLCVNGQCKNTEGSFRCTC 1106
Query: 404 PQGYK---GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY----AGPRCEMD 456
QGY+ D ED+DEC + + C H G+C NT+G+F C C +GY G CE D
Sbjct: 1107 GQGYQLSAAKDQCEDIDEC--QHRHLCAH-GQCRNTEGSFQCVCDQGYRASGLGDHCE-D 1162
Query: 457 INECHSDP--CQNDATCLDKIGGFTCLCMPGFK---GVHCELEINECQ-SNPCVNNGQCV 510
INEC D CQ C++ G + C C GF+ C+ +INEC+ C G+C+
Sbjct: 1163 INECLEDKSVCQR-GDCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECL 1220
Query: 511 DKVNRFQCLCPPGFT----GPVCQIDIDDC-SSTPCLNGAKCIDHPNGYECQCATGF--- 562
+ F C+C GF+ G C+ DID+C ++T C + C + + C C GF
Sbjct: 1221 NTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 1279
Query: 563 -TGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCIC---NPGY--MGAIC---------- 604
G C + ++ C+ C C++ S+ C+C N Y M C
Sbjct: 1280 QDGQGCVD-VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV 1338
Query: 605 -----SDQIDECYSSPCLNDGRCID-----LVNGYQCNCQPGTS-GVNCEINFDDCASNP 653
++ ECY + LND D V +C C G G NCEI
Sbjct: 1339 DVDQPKEEKKECYYN--LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTA 1396
Query: 654 CIHGICMDGINRYSCVCSPGFTGQRCNIDIDEC---ASNPCRKGATCINGVNGFRCICPE 710
+C G S G D DEC C+ G C+N G+ C C +
Sbjct: 1397 EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQ 1455
Query: 711 GPHHP----SCYSQVNECLS-NPCIHGNCTGGLSGYKCLC------DAGWVGINCEVDKN 759
G ++ C+ ++EC + CI G C Y C C DA + N
Sbjct: 1456 GTYYDPVKLQCF-DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESN 1514
Query: 760 ECLSNPCQNGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF------- 811
E + C ++L + Y C+ K Q EC C G +
Sbjct: 1515 EQIEETDVYQDLCWEHLSDEYVCSRPLVGK----QTTYTEC----CCLYGEAWGMQCALC 1566
Query: 812 --DDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQR 869
D Y C +P TG+ P A+ S E YT P + R
Sbjct: 1567 PLKDSDDYAQLCNIPVTGRR----------QPYGRDALVDFS---EQYTPEADPYFIQDR 1613
Query: 870 CTIDIDECISKPC-----MNHGLCHNTQGSYMCECPPGF----SGMDCEEDIDDC----- 915
+E ++ C +G C Q Y C+C G+ + M C D+++C
Sbjct: 1614 FLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTC-VDVNECDELNN 1672
Query: 916 LANPCQNGGSCMDGVNTFSCLCLPGF 941
+ C+N C++ ++ CLCLPG+
Sbjct: 1673 RMSLCKN-AKCINTDGSYKCLCLPGY 1697
Score = 213 bits (542), Expect = 2e-54
Identities = 232/868 (26%), Positives = 338/868 (38%), Gaps = 186/868 (21%)
Query: 298 DVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSE---NIDDCAFAS--CTPGST 352
+++EC + P+ C G C N Y C+C G+ + +ID+C C+ G
Sbjct: 874 EINECTVNPDIC-GAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR- 931
Query: 353 CIDRVASFSCMCPEG----KAGLLCHLDDACIS-NPCHKGALCDTNPLNGQYICT-CPQG 406
C + SF C+CP G + G C D C+ + C +G +T G + C C G
Sbjct: 932 CENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTV---GAFRCEYCDSG 988
Query: 407 YKGADC--TEDVDECAMANSNPCEHAGKCVNTDGAFHC-ECLKGYAGPRCE-MDINECHS 462
Y+ ED+DEC ++ P E +CVN+ G++ C C +G+ G + +D++EC
Sbjct: 989 YRMTQRGRCEDIDECLNPSTCPDE---QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE 1045
Query: 463 DPCQNDATCLDKIGGFTCLCMPGFKGV----HCELEINECQSNPCVNNGQCVDKVNRFQC 518
+ C + G + C C G+ HC +I+ECQ NGQC + F+C
Sbjct: 1046 PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQCKNTEGSFRC 1104
Query: 519 LCPPGF----TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFT----GVLCEEN 570
C G+ C+ DID+C +C + ++C C G+ G CE+
Sbjct: 1105 TCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED- 1162
Query: 571 IDNC--DPDPCHHGQCQDGIDSYTCICNPGYM---GAICSDQIDEC-YSSPCLNDGRCID 624
I+ C D C G C + SY C C G+ C D I+EC + C G C++
Sbjct: 1163 INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQD-INECEHPGLCGPQGECLN 1221
Query: 625 LVNGYQCNCQPGTS----GVNCEINFDDCASNPCI--HGICMDGINRYSCVCSPGFT--- 675
+ C CQ G S G CE + D+C +N HG C + + C+C GF
Sbjct: 1222 TEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ 1280
Query: 676 -GQRCNIDIDECA--SNPCRKGATCINGVNGFRCICPE-----GPHHPSCYSQVN----- 722
GQ C +D++EC S C + A C N F C+C + P C S+ +
Sbjct: 1281 DGQGC-VDVNECELLSGVCGE-AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV 1338
Query: 723 ----------ECLSNPCIHGNCTGGLSG----YKCLCD--AGWVGINCEV---------- 756
EC N C L+ +C C AGW G NCE+
Sbjct: 1339 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGW-GDNCEIFPCPVLGTAE 1397
Query: 757 ---------------------------DKNECL---SNPCQNGGTCDNLVNGYRCTCKKG 786
D +ECL C+NG C N GY C CK+G
Sbjct: 1398 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQG 1456
Query: 787 --FKGYNCQV-NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCE 843
+ Q ++DEC G C + Y C C P ++ S C
Sbjct: 1457 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHP--------MVLDASEKRCI 1508
Query: 844 NAAVCKES-PNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPG 902
A E + Y LC W+ + + S+P + + C C G
Sbjct: 1509 RPAESNEQIEETDVYQDLC---WEH----LSDEYVCSRPLVGKQTTYTE-----CCCLYG 1556
Query: 903 FS-GMDCE----EDIDDC--LANPCQNG-------GSCMDGVNTFSCLCLPGFTGDKCQT 948
+ GM C +D DD L N G + +D ++ P F D+
Sbjct: 1557 EAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLN 1616
Query: 949 DMNECLSEPCK--NG---GTCSDYVNSYTCKCQAGFDGVHCEN------NINECTE---- 993
E +E C NG G C YTC C FDG H + ++NEC E
Sbjct: 1617 SFEELQAEECGILNGCENGRCVRVQEGYTCDC---FDGYHLDTAKMTCVDVNECDELNNR 1673
Query: 994 -SSCFNGGTCVDGINSFSCLCPVGFTGS 1020
S C N C++ S+ CLC G+ S
Sbjct: 1674 MSLCKNA-KCINTDGSYKCLCLPGYVPS 1700
Score = 199 bits (505), Expect = 4e-50
Identities = 175/647 (27%), Positives = 264/647 (40%), Gaps = 103/647 (15%)
Query: 715 PSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCE---VDKNEC--LSNPCQ 767
P+ +++NEC NP C G+C Y C+C G+ + VD +EC + + C
Sbjct: 869 PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 928
Query: 768 NGGTCDNLVNGYRCTCKKGF----KGYNCQVNIDECASNPCLNQGTCFDDISGYTC-HCV 822
G C+N + C C GF +G NC +++DEC +G C + + + C +C
Sbjct: 929 Q-GRCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCD 986
Query: 823 LPY---TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCL-CAP---GWQGQRCTIDID 875
Y C+ + +P+ C + C SP SY C+ C GW GQ +D+D
Sbjct: 987 SGYRMTQRGRCEDIDECLNPSTCPDEQ-CVNSPG--SYQCVPCTEGFRGWNGQ--CLDVD 1041
Query: 876 ECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEE---DIDDC-LANPCQNGGSCMDGVN 931
EC+ +G C N +GSYMC C G++ + DID+C N C N G C +
Sbjct: 1042 ECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN-GQCKNTEG 1100
Query: 932 TFSCLCLPGF----TGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD----GVH 983
+F C C G+ D+C+ D++EC G C + S+ C C G+ G H
Sbjct: 1101 SFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDH 1159
Query: 984 CENNINECTE-SSCFNGGTCVDGINSFSCLCPVGF--TGSFCLHEINECSSHP--CLNEG 1038
CE +INEC E S G C++ S+ C CP GF + +INEC HP C +G
Sbjct: 1160 CE-DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQG 1217
Query: 1039 TCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWA 1094
C++ G++ C C G++ G+ C+ + + + C + G C +CLC G+
Sbjct: 1218 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ 1277
Query: 1095 GAYCDVPNVSCDIAASRRGVLVEHLCQH---SGVCINAGNTHYCQCPLGYTGSYCEEQLD 1151
V + GV E C++ S +C+ A G S LD
Sbjct: 1278 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD 1337
Query: 1152 ECASNPCQHGATC--------------SDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQ 1197
P + C + + C C G D C+ PC
Sbjct: 1338 VDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGW------GDNCEIFPCP 1391
Query: 1198 NGGTCIDLVNHFKCSCPPGTRGLLCEE-----------NIDDCAR-GPHCLNGGQCMDRI 1245
GT F CP G + E + D+C G G C++
Sbjct: 1392 VLGTA-----EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTR 1446
Query: 1246 GGYSCRCLPG----------FAGERCEGDINECLSNPC-SSEGSLDC 1281
GY C C G F + C+ D + C+ C ++EGS +C
Sbjct: 1447 PGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNC 1492
Score = 191 bits (485), Expect = 8e-48
Identities = 224/825 (27%), Positives = 314/825 (38%), Gaps = 187/825 (22%)
Query: 89 TCRCASGFTGEDCQYSTSH--PCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE----C 142
TC C G+ + Q C + + G C + ++ C C GF E C
Sbjct: 898 TCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN-TEGSFLCICPAGFMASEEGTNC 956
Query: 143 QWTDACLSHPCANGSTCTTVANQFSCK-CLTGFTGQ---KCETDVNECDIPGHCQHGGTC 198
D CL C F C+ C +G+ +CE D++EC P C C
Sbjct: 957 IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCE-DIDECLNPSTCPDE-QC 1014
Query: 199 LNLPGSYQC-QCPQGFTGQYCDSLYVP--CAPSPCVNGGTCRQTGDFTFECNCLPGFEGS 255
+N PGSYQC C +GF G L V P+ C NG G + C+C G+ +
Sbjct: 1015 VNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYM--CSCHKGYTRT 1072
Query: 256 TCERNIDDCPNHRCQNGGVCVDGV-----NTYNCRCPPQW---TGQFCTEDVDECLLQPN 307
++ D CQ G +CV+G ++ C C + + ED+DEC + +
Sbjct: 1073 PDHKHCRDIDE--CQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHR-H 1129
Query: 308 ACQNGGTCANRNGGYGCVCVNGWS----GDDCSENIDDCAF--ASCTPGSTCIDRVASFS 361
C +G C N G + CVC G+ GD C E+I++C + C G CI+ S+
Sbjct: 1130 LCAHG-QCRNTEGSFQCVCDQGYRASGLGDHC-EDINECLEDKSVCQRGD-CINTAGSYD 1186
Query: 362 CMCPEGKAGLLCHLDD--ACIS-NPCHKGALCDTNP----LNGQYICTCPQGYK----GA 410
C CP+G LDD C N C LC G + C C QG+ G
Sbjct: 1187 CTCPDG-----FQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 1241
Query: 411 DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPR----CEMDINECH--SDP 464
C ED+DEC N+ C+ G C NT G+F C C +G+ P+ C +D+NEC S
Sbjct: 1242 TC-EDIDECV--NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC-VDVNECELLSGV 1297
Query: 465 CQNDATCLDKIGGFTCLC---------------------------MPGFKGVHCELEINE 497
C +A C + G F C+C P + C +N+
Sbjct: 1298 C-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLND 1356
Query: 498 C-------------QSNPCVNNGQCVDKVNRFQC----------LCPPGF---------- 524
Q C + D F C +CP G
Sbjct: 1357 ASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSS 1416
Query: 525 -TGPVCQIDIDDC---SSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDNC-D 575
G D D+C C NG C++ GYEC C G + C + +D C D
Sbjct: 1417 EAGGENYKDADECLLFGQEICKNGF-CLNTRPGYECYCKQGTYYDPVKLQCFD-MDECQD 1474
Query: 576 PDPCHHGQCQDGIDSYTCIC-NPGYMGAI---------CSDQIDEC--YSSPC---LNDG 620
P C GQC + SY C C +P + A ++QI+E Y C L+D
Sbjct: 1475 PSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDE 1534
Query: 621 R-CIDLVNGYQ-----CNCQPGTS-GVNCEI----NFDDCAS----------NPCIHGIC 659
C + G Q C C G + G+ C + + DD A P
Sbjct: 1535 YVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDAL 1594
Query: 660 MDGINRYSCVCSPGFTGQRC-----NIDIDECAS-NPCRKGATCINGVNGFRCICPEGPH 713
+D +Y+ P F R + +EC N C G C+ G+ C C +G H
Sbjct: 1595 VDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR-CVRVQEGYTCDCFDGYH 1653
Query: 714 HPSCYS---QVNEC--LSNP---CIHGNCTGGLSGYKCLCDAGWV 750
+ VNEC L+N C + C YKCLC G+V
Sbjct: 1654 LDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1698
Score = 167 bits (423), Expect = 1e-40
Identities = 138/460 (30%), Positives = 202/460 (43%), Gaps = 59/460 (12%)
Query: 873 DIDECISKPCM-NHGLCHNTQGSYMCECPPGFSGMDCEE---DIDDC--LANPCQNGGSC 926
+I+EC P + G C N Y C C G+ + + DID+C + + C G C
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG-RC 932
Query: 927 MDGVNTFSCLCLPGFTGDKCQT---DMNECLSEPCKNGGTCSDYVNSYTCK-CQAGFDGV 982
+ +F C+C GF + T D++ECL G C + V ++ C+ C +G+
Sbjct: 933 ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 992
Query: 983 H---CENNINECTESSCFNGGTCVDGINSFSCL-CPVGFTG--SFCLHEINECSSHPCLN 1036
CE+ I+EC S CV+ S+ C+ C GF G CL +++EC
Sbjct: 993 QRGRCED-IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL-DVDECLEPNVCA 1050
Query: 1037 EGTCVDGLGTYRCSCPLGYTG----KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSG 1092
G C + G+Y CSC GYT K+C+ + + C N G C + +C C G
Sbjct: 1051 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN-GQCKNTEGSFRCTCGQG 1109
Query: 1093 WAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT----GSYCEE 1148
+ + D R HLC H G C N + C C GY G +CE+
Sbjct: 1110 YQLSAAKDQCEDIDECQHR------HLCAH-GQCRNTEGSFQCVCDQGYRASGLGDHCED 1162
Query: 1149 QLDECASNP--CQHGATCSDFIGGYRCECVPGYQ---GVNCEYEVDECQNQP-CQNGGTC 1202
++EC + CQ G C + G Y C C G+Q C+ +++EC++ C G C
Sbjct: 1163 -INECLEDKSVCQRG-DCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGEC 1219
Query: 1203 IDLVNHFKCSCPPG----TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA- 1257
++ F C C G G CE+ ID+C C + G C + G + C C GF
Sbjct: 1220 LNTEGSFHCVCQQGFSISADGRTCED-IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA 1278
Query: 1258 ---GERCEGDINEC--LSNPCSSEGSLDCIQLTNDYLCVC 1292
G+ C D+NEC LS C G C + +LCVC
Sbjct: 1279 PQDGQGCV-DVNECELLSGVC---GEAFCENVEGSFLCVC 1314
Score = 162 bits (411), Expect = 3e-39
Identities = 133/441 (30%), Positives = 193/441 (43%), Gaps = 64/441 (14%)
Query: 948 TDMNECLSEPCKNG-GTCSDYVNSYTCKCQAGFDGVHCEN---NINECTE-SSCFNGGTC 1002
T++NEC P G G C + YTC C G+ + +I+ECT+ + G C
Sbjct: 873 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 932
Query: 1003 VDGINSFSCLCPVGFT----GSFCLHEINECSSHPCLNEGTCVDGLGTYRCS-CPLGYTG 1057
+ SF C+CP GF G+ C+ +++EC EG CV+ +G +RC C GY
Sbjct: 933 ENTEGSFLCICPAGFMASEEGTNCI-DVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRM 991
Query: 1058 KN---CQTLVNLCSRSPCKNKGTCVQKKAESQCL-CPSG---WAGAYCDVPNVSCDIAAS 1110
C+ + + S C ++ CV QC+ C G W G DV
Sbjct: 992 TQRGRCEDIDECLNPSTCPDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC------- 1043
Query: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS----YCEEQLDECAS-NPCQHGATCS 1165
L ++C + G C N ++ C C GYT + +C + +DEC N C +G C
Sbjct: 1044 ----LEPNVCAN-GDCSNLEGSYMCSCHKGYTRTPDHKHCRD-IDECQQGNLCVNGQ-CK 1096
Query: 1166 DFIGGYRCECVPGYQ----GVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR--- 1218
+ G +RC C GYQ CE ++DECQ++ G C + F+C C G R
Sbjct: 1097 NTEGSFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASG 1155
Query: 1219 -GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA---GERCEGDINECLSNP-- 1272
G CE+ I++C G C++ G Y C C GF + C+ DINEC +P
Sbjct: 1156 LGDHCED-INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQ-DINEC-EHPGL 1212
Query: 1273 CSSEGSLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMPCLNGGTCAVASNMPDG 1328
C +G +C+ + CVC+ F+ GR CE + C + G C N
Sbjct: 1213 CGPQG--ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFC---DNTAGS 1267
Query: 1329 FICRCPPGFSGARCQSSCGQV 1349
F C C GF + C V
Sbjct: 1268 FRCLCYQGFQAPQDGQGCVDV 1288
Score = 155 bits (391), Expect = 6e-37
Identities = 195/735 (26%), Positives = 281/735 (38%), Gaps = 174/735 (23%)
Query: 27 QCRDGYEPCVNEGMC----VTYHNGTGYC-KCPEGFLG--EYCQHRDPC-EKNRCQNGGT 78
+C D + C+N C G+ C C EGF G C D C E N C NG
Sbjct: 996 RCED-IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD- 1053
Query: 79 CVAQAMLGKATCRCASGFTGE-DCQYSTS-HPCFVSRPCLNGGTCHMLSRDTYECTCQVG 136
+ G C C G+T D ++ C C+NG + + ++ CTC G
Sbjct: 1054 --CSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN--TEGSFRCTCGQG 1109
Query: 137 F----TGKECQWTDACLS-HPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNEC- 186
+ +C+ D C H CA+G C F C C G+ G CE D+NEC
Sbjct: 1110 YQLSAAKDQCEDIDECQHRHLCAHGQ-CRNTEGSFQCVCDQGYRASGLGDHCE-DINECL 1167
Query: 187 DIPGHCQHGGTCLNLPGSYQCQCPQGFT---GQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
+ CQ G C+N GSY C CP GF + C + P C G C T + +
Sbjct: 1168 EDKSVCQRGD-CINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNT-EGS 1225
Query: 244 FECNCLPGF----EGSTCERNIDDCPNHR-CQNGGVCVDGVNTYNCRC-----PPQWTGQ 293
F C C GF +G TCE +ID+C N+ C + G C + ++ C C PQ GQ
Sbjct: 1226 FHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ-DGQ 1283
Query: 294 FCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNG--------------WSGD------ 333
C DV+EC L C C N G + CVC + S D
Sbjct: 1284 GCV-DVNECELLSGVCGEA-FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVD 1341
Query: 334 -------DCSENIDDCAFAS-------------CTPGSTCIDRVASFSC----------M 363
+C N++D + CT G+ D F C M
Sbjct: 1342 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM 1401
Query: 364 CPEGK-----------AGLLCHLD-DACI---SNPCHKGALCDTNPLNGQYICTCPQGYK 408
CP+GK AG + D D C+ C G +T P Y C C QG
Sbjct: 1402 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRP---GYECYCKQGTY 1458
Query: 409 ----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC----LKGYAGPRC------- 453
C D+DEC +S C G+CVNT+G+++C C + + RC
Sbjct: 1459 YDPVKLQCF-DMDECQDPSS--CID-GQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESN 1514
Query: 454 -EMDINECHSDPC----QNDATCLDKIGG-----FTCLCMPGFK-GVHCEL-------EI 495
+++ + + D C ++ C + G C C+ G G+ C L +
Sbjct: 1515 EQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDY 1574
Query: 496 NECQSNPCVNNGQ------CVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC--LNGA-- 545
+ + P Q VD ++ P F ++ + C LNG
Sbjct: 1575 AQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCEN 1634
Query: 546 -KCIDHPNGYECQCATGF---TGVLCEENIDNCDP-----DPCHHGQCQDGIDSYTCICN 596
+C+ GY C C G+ T + +++ CD C + +C + SY C+C
Sbjct: 1635 GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCL 1694
Query: 597 PGYMGAICSDQIDEC 611
PGY + SD+ + C
Sbjct: 1695 PGY---VPSDKPNYC 1706
Score = 147 bits (371), Expect = 1e-34
Identities = 165/721 (22%), Positives = 270/721 (37%), Gaps = 132/721 (18%)
Query: 27 QCRDGYEPCVNEGMCVTYH----NGTGYCKCPEGFLG----EYCQHRDPCEK-NRCQNGG 77
QC D + C+ +C G+ C C +G+ ++C+ D C++ N C NG
Sbjct: 1036 QCLD-VDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQ 1094
Query: 78 TCVAQAMLGKATCRCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQV 135
+ G C C G+ + Q C C +G + + +++C C
Sbjct: 1095 CKNTE---GSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRN--TEGSFQCVCDQ 1149
Query: 136 GFT----GKECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQKCET--DVNECD 187
G+ G C+ + CL C G C A + C C GF +T D+NEC+
Sbjct: 1150 GYRASGLGDHCEDINECLEDKSVCQRGD-CINTAGSYDCTCPDGFQLDDNKTCQDINECE 1208
Query: 188 IPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
PG C G CLN GS+ C C QGF+ G+ C+ + + C + G C T +
Sbjct: 1209 HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAG-S 1267
Query: 244 FECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECL 303
F C C GF+ Q+G CV DV+EC
Sbjct: 1268 FRCLCYQGFQAP--------------QDGQGCV---------------------DVNECE 1292
Query: 304 LQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID--RVASFS 361
L C C N G + CVC + + S C + T +D +
Sbjct: 1293 LLSGVC-GEAFCENVEGSFLCVCAD--ENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKE 1349
Query: 362 CMCPEGKAGLLCHL-------DDACISNPCHKGALCDTNPL----NGQYICTCPQG---- 406
C A L ++ + C ++ G C+ P ++ CP+G
Sbjct: 1350 CYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFV 1409
Query: 407 -------YKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKG-YAGP---RCEM 455
G + +D DEC + C++ G C+NT + C C +G Y P +C
Sbjct: 1410 PAGESSSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQGTYYDPVKLQC-F 1467
Query: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNR 515
D++EC D C++ G + C C L+ +E + + + +++ +
Sbjct: 1468 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPM-----VLDASEKRCIRPAESNEQIEETDV 1522
Query: 516 FQCLCPPGFTGP-VCQIDI--DDCSSTPCLNGAKCIDHPNGYECQCA------TGFTGVL 566
+Q LC + VC + + T C C + + QCA + L
Sbjct: 1523 YQDLCWEHLSDEYVCSRPLVGKQTTYTEC-----CCLYGEAWGMQCALCPLKDSDDYAQL 1577
Query: 567 CEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC-----LNDGR 621
C + P D + YT +P ++ + +E + C +GR
Sbjct: 1578 CNIPVTG-RRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR 1636
Query: 622 CIDLVNGYQCNCQPG----TSGVNC-EINFDDCASNP---CIHGICMDGINRYSCVCSPG 673
C+ + GY C+C G T+ + C ++N D +N C + C++ Y C+C PG
Sbjct: 1637 CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1696
Query: 674 F 674
+
Sbjct: 1697 Y 1697
Score = 102 bits (255), Expect = 4e-21
Identities = 107/402 (26%), Positives = 150/402 (37%), Gaps = 94/402 (23%)
Query: 1123 SGVCINAGNTHYCQCPLGYTGSYCEEQ---LDECAS--NPCQHGATCSDFIGGYRCECVP 1177
+G CIN + C C GY S + + +DEC + C G C + G + C C
Sbjct: 887 AGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR-CENTEGSFLCICPA 945
Query: 1178 GY----QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCS-CPPG---TRGLLCEENIDDC 1229
G+ +G NC +VDEC G C++ V F+C C G T+ CE+ ID+C
Sbjct: 946 GFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCED-IDEC 1003
Query: 1230 ARGPHCLNGGQCMDRIGGYSC-RCLPGFAGERCEG-DINECLSNPCSSEGSLDCIQLTND 1287
C + QC++ G Y C C GF G + D++ECL + G DC L
Sbjct: 1004 LNPSTCPDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANG--DCSNLEGS 1060
Query: 1288 YLCVCRSAFT----GRHCETFVDVCPQ-MPCLNGG----------TC------------- 1319
Y+C C +T +HC +D C Q C+NG TC
Sbjct: 1061 YMCSCHKGYTRTPDHKHCRD-IDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQC 1119
Query: 1320 --------------AVASNMPDGFICRCPPGFSGARCQSSCGQVK--------CRKGEQC 1357
N F C C G+ + C + C++G+ C
Sbjct: 1120 EDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGD-C 1178
Query: 1358 VHTASGPRCFCPS--PRDCESGCAS-SPCQHGGSCHPQRQ----PPYYSCQCAPPFS--- 1407
++TA C CP D C + C+H G C PQ + + C C FS
Sbjct: 1179 INTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISA 1238
Query: 1408 -GSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHAC 1448
G CE C++ D G CD S C
Sbjct: 1239 DGRTCE--------DIDECVNNTVCDS--HGFCDNTAGSFRC 1270
Score = 55.1 bits (131), Expect = 9e-07
Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 13/119 (10%)
Query: 808 GTCFDDISGYTCHCVLPYTGKN---CQTVLAPCSPNPCENAAVCKESPNFESYTCL--CA 862
G CF + G C LP K C TV N C+ C + P++ Y + C
Sbjct: 557 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQK---CPKKPSYHGYNQMMECL 613
Query: 863 PGWQGQRCTI--DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
PG++ T DI+EC + +G C NT GSY C C GF + C+ +P
Sbjct: 614 PGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGP---DPTFSSCVPDP 669
Score = 52.0 bits (123), Expect = 7e-06
Identities = 75/307 (24%), Positives = 104/307 (33%), Gaps = 76/307 (24%)
Query: 276 VDGVNTYNCRCPPQWT----GQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS 331
+ GVN RC W+ Q CT+ C+ CQNGG C CVC G
Sbjct: 163 LQGVNVCGGRCCHGWSKAPGSQRCTKP--SCV---PPCQNGGMCLRPQL---CVCKPGTK 214
Query: 332 GDDC----SENIDDCAFASCTPGSTC-------------------IDRVASFSCMC---- 364
G C +++ F +PG+ + RV+ + M
Sbjct: 215 GKACETIAAQDTSSPVFGGQSPGAASSWGPPEQAAKHTSSKKADTLPRVSPVAQMTLTLK 274
Query: 365 PEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICT-----CPQGYKGADCTED---- 415
P+ GL + P ++ + +Y+ +G G TE
Sbjct: 275 PKPSVGLPQQIHSQV--TPLSSQSVVIHHGQTQEYVLKPKYFPAQKGISGEQSTEGSFPL 332
Query: 416 --VDECAMANSNPCEHAG--KCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATC 471
V + A H G K V T C KG CE N T
Sbjct: 333 RYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKG----------NTTTL 382
Query: 472 LDKIG-GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQ 530
+ + G L F+ V C L PC+N GQC +R +C CPP FTG +CQ
Sbjct: 383 ISENGHAADTLTATNFRVVICHL--------PCMNGGQCS---SRDKCQCPPNFTGKLCQ 431
Query: 531 IDIDDCS 537
I + S
Sbjct: 432 IPVHGAS 438
Score = 52.0 bits (123), Expect = 7e-06
Identities = 53/196 (27%), Positives = 77/196 (39%), Gaps = 26/196 (13%)
Query: 1264 DINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMPCL-NGGT 1318
+INEC NP G+ CI L Y C+C + R C +D C Q+ L + G
Sbjct: 874 EINECTVNPDIC-GAGHCINLPVRYTCICYEGYRFSEQQRKCVD-IDECTQVQHLCSQGR 931
Query: 1319 CAVASNMPDGFICRCPPGFSGARCQSSCGQVK-------CRKGEQCVHTASGPRC-FCPS 1370
C N F+C CP GF + ++C V C +G CV+T RC +C S
Sbjct: 932 C---ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEG-HCVNTVGAFRCEYCDS 987
Query: 1371 P-RDCESGCAS--SPCQHGGSCHPQR---QPPYYSC-QCAPPFSGSRCELYTAPPSTPPA 1423
R + G C + +C ++ P Y C C F G + P
Sbjct: 988 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN 1047
Query: 1424 TCLSQYCADKARDGVC 1439
C + C++ +C
Sbjct: 1048 VCANGDCSNLEGSYMC 1063
Score = 45.8 bits (107), Expect = 5e-04
Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 8/66 (12%)
Query: 169 KCLTGF---TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC 225
+CL G+ C+ D+NEC + G C +G CLN GSY+C C GF D + C
Sbjct: 611 ECLPGYKRVNNTFCQ-DINECQLQGVCPNG-ECLNTMGSYRCTCKIGFGP---DPTFSSC 665
Query: 226 APSPCV 231
P P V
Sbjct: 666 VPDPPV 671
Score = 45.4 bits (106), Expect = 7e-04
Identities = 82/359 (22%), Positives = 126/359 (35%), Gaps = 80/359 (22%)
Query: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDG--LGTYRC---- 1049
C NGG C + C CP FTG C ++ S P L + + G LGT+
Sbjct: 407 CMNGGQCS---SRDKCQCPPNFTGKLCQIPVHGASV-PKLYQHSQQPGKALGTHVIHSTH 462
Query: 1050 SCPLGYTG------KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAG--AYCDVP 1101
+ PL T K +VN+ + P + VQ S+ P+G A
Sbjct: 463 TLPLTVTSQQGVKVKFPPNIVNIHVKHPPE---ASVQIHQVSRIDGPTGQKTKEAQPGQS 519
Query: 1102 NVSCDIAASRRGVLVEHLCQHSGVCIN----AGNTHYCQCPLGYTGSYCEEQL------D 1151
VS ++ + H V + A T +C GS C + L +
Sbjct: 520 QVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQE 579
Query: 1152 ECAS--------NPCQHGATCSDFIG-GYRCECVPGYQGVNCEY--EVDECQNQPCQNGG 1200
+C N CQ + G EC+PGY+ VN + +++ECQ Q G
Sbjct: 580 DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNG 639
Query: 1201 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLN--GGQCMDRIGGYSCRCLPGFAG 1258
C++ + ++C+C G + C P ++ G C + +G
Sbjct: 640 ECLNTMGSYRCTCKIGFGP---DPTFSSCVPDPPVISEEKGPCYRLVS----------SG 686
Query: 1259 ERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE--------TFVDVCP 1309
+C +P S + LT C G HCE F ++CP
Sbjct: 687 RQC--------MHPLS-------VHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICP 730
Score = 42.0 bits (97), Expect = 0.007
Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 5/49 (10%)
Query: 482 CMPGFKGVH---CELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGP 527
C+PG+K V+ C+ +INECQ NG+C++ + ++C C GF GP
Sbjct: 612 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGF-GP 658
Score = 40.8 bits (94), Expect = 0.017
Identities = 38/148 (25%), Positives = 56/148 (37%), Gaps = 22/148 (14%)
Query: 574 CDPDPCHHGQCQDGIDSYTCICNPGYM---GAICSDQIDECYSSPCLNDGRCIDLVNGYQ 630
C P +HG Q C PGY C D I+EC +G C++ + Y+
Sbjct: 597 CPKKPSYHGYNQ------MMECLPGYKRVNNTFCQD-INECQLQGVCPNGECLNTMGSYR 649
Query: 631 CNCQPGTSGVNCEINFDDCASNPCI----HGICMDGINR-YSCV--CSPGFTGQRCNIDI 683
C C+ G + F C +P + G C ++ C+ S T Q C +
Sbjct: 650 CTCK---IGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV 706
Query: 684 DECASNPCRKGATCINGVNGFRCICPEG 711
+ C K + G F+ ICP G
Sbjct: 707 GKAWGPHCEK--CPLPGTAAFKEICPGG 732
Score = 39.7 bits (91), Expect = 0.037
Identities = 82/350 (23%), Positives = 118/350 (33%), Gaps = 78/350 (22%)
Query: 66 DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDC---QYSTSHPC--FVSRPCLNGGT 120
D CE C GT M K +G + + Y + C F C NG
Sbjct: 1383 DNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFC 1442
Query: 121 CHMLSRDTYECTCQVG----------FTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
+ +R YEC C+ G F ECQ +C+ C N ++C C
Sbjct: 1443 LN--TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVN------TEGSYNCFC 1494
Query: 171 ----LTGFTGQKC-----------ETDVNE------------CDIP--GHCQHGGTCLNL 201
+ + ++C ETDV + C P G C L
Sbjct: 1495 THPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCL 1554
Query: 202 PGS---YQCQ-CPQGFTGQYCDSLYVPCAP--SPCVNGGTCRQTGDFTFECN---CLPGF 252
G QC CP + Y +P P + +T E + F
Sbjct: 1555 YGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRF 1614
Query: 253 EGSTCERNIDDCPN-HRCQNGGVCVDGVNTYNCRCPPQW---TGQFCTEDVDECLLQPNA 308
S E ++C + C+NG CV Y C C + T + DV+EC N
Sbjct: 1615 LNSFEELQAEECGILNGCENGR-CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNR 1673
Query: 309 ---CQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID 355
C+N C N +G Y C+C+ G+ D CTP +T ++
Sbjct: 1674 MSLCKNA-KCINTDGSYKCLCLPGYVPSDKPN--------YCTPLNTALN 1714
Score = 38.9 bits (89), Expect = 0.063
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 13/87 (14%)
Query: 382 NPCHKGALCDTNPLNGQY--ICTCPQGYKGADCT--EDVDECAMANSNPCEHAGKCVNTD 437
N C K C P Y + C GYK + T +D++EC + P G+C+NT
Sbjct: 592 NKCQK---CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCP---NGECLNTM 645
Query: 438 GAFHCECLKGYAGPRCEMDINECHSDP 464
G++ C C G+ GP + + C DP
Sbjct: 646 GSYRCTCKIGF-GP--DPTFSSCVPDP 669
Score = 38.5 bits (88), Expect = 0.083
Identities = 82/349 (23%), Positives = 117/349 (33%), Gaps = 75/349 (21%)
Query: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQ-----GTCFDDISGYTC 819
PC NGG C + +C C F G CQ+ + AS P L Q G ++
Sbjct: 406 PCMNGGQCSSRD---KCQCPPNFTGKLCQIPVHG-ASVPKLYQHSQQPGKALGTHVIHST 461
Query: 820 HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS 879
H LP T + Q V PN + + + G GQ+ T + S
Sbjct: 462 H-TLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQK-TKEAQPGQS 519
Query: 880 K------PCMNHGLCHNT-----------------------QGSYMCECPPGFSGMDCEE 910
+ P H+T Q + +C G+ +E
Sbjct: 520 QVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQE 579
Query: 911 DIDDCLA-----NPCQNGGS--CMDGVNTFSCLCLPGF---TGDKCQTDMNECLSEPCKN 960
D + N CQ G N CLPG+ CQ D+NEC +
Sbjct: 580 DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMM-ECLPGYKRVNNTFCQ-DINECQLQGVCP 637
Query: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCF--------NGGTCVDGINS-FSC 1011
G C + + SY C C+ GF + T SSC G C ++S C
Sbjct: 638 NGECLNTMGSYRCTCKIGFG--------PDPTFSSCVPDPPVISEEKGPCYRLVSSGRQC 689
Query: 1012 LCP--VGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCP--LGYT 1056
+ P V T C + + C E + G ++ CP +GYT
Sbjct: 690 MHPLSVHLTKQLCCCSVGKAWGPHC--EKCPLPGTAAFKEICPGGMGYT 736
Score = 38.5 bits (88), Expect = 0.083
Identities = 56/257 (21%), Positives = 94/257 (36%), Gaps = 48/257 (18%)
Query: 152 PCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP---GHCQHGGTCL--------- 199
PC NG C++ + C+C FTG+ C+ V+ +P H Q G L
Sbjct: 406 PCMNGGQCSS---RDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTH 462
Query: 200 NLPGSYQCQCPQGFTGQY---CDSLYVPCAPSPCVNGGTCRQ----TGDFTFECNCLPG- 251
LP + Q QG ++ +++V P V + TG T E PG
Sbjct: 463 TLPLTVTSQ--QGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQ--PGQ 518
Query: 252 ----FEGSTCER--NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQ 305
++G ++ I +H+ V T RC + G C + + Q
Sbjct: 519 SQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQ 578
Query: 306 PNACQNGGT---------CANRNGGYG----CVCVNGWS--GDDCSENIDDCAFASCTPG 350
+ C GT C + +G C+ G+ + ++I++C P
Sbjct: 579 EDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPN 638
Query: 351 STCIDRVASFSCMCPEG 367
C++ + S+ C C G
Sbjct: 639 GECLNTMGSYRCTCKIG 655
Score = 38.5 bits (88), Expect = 0.083
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 22/81 (27%)
Query: 708 CPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC-LSNPC 766
CP+ P + Y+Q+ ECL GYK + + C+ D NEC L C
Sbjct: 597 CPKKPSYHG-YNQMMECLP-------------GYKRVNNTF-----CQ-DINECQLQGVC 636
Query: 767 QNGGTCDNLVNGYRCTCKKGF 787
NG C N + YRCTCK GF
Sbjct: 637 PNG-ECLNTMGSYRCTCKIGF 656
Score = 38.5 bits (88), Expect = 0.083
Identities = 42/129 (32%), Positives = 50/129 (38%), Gaps = 31/129 (24%)
Query: 294 FCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPG--- 350
FC +D++EC LQ C NG C N G Y C C G+ D F+SC P
Sbjct: 623 FC-QDINECQLQ-GVCPNG-ECLNTMGSYRCTCKIGFGPDP--------TFSSCVPDPPV 671
Query: 351 -----STCIDRVAS-FSCMCPEGKAGLLCHLDD--ACISNPCHKGALCDTNPLNG----Q 398
C V+S CM P L HL C S G C+ PL G +
Sbjct: 672 ISEEKGPCYRLVSSGRQCMHP-----LSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFK 726
Query: 399 YICTCPQGY 407
IC GY
Sbjct: 727 EICPGGMGY 735
Score = 37.7 bits (86), Expect = 0.14
Identities = 27/76 (35%), Positives = 31/76 (40%), Gaps = 22/76 (28%)
Query: 183 VNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDF 242
VN C G C HG + PGS +C P C P PC NGG C +
Sbjct: 166 VNVCG--GRCCHGWS--KAPGSQRCTKPS-------------CVP-PCQNGGMCLRPQ-- 205
Query: 243 TFECNCLPGFEGSTCE 258
C C PG +G CE
Sbjct: 206 --LCVCKPGTKGKACE 219
Score = 37.7 bits (86), Expect = 0.14
Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 10/69 (14%)
Query: 861 CAPGWQ----GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCL 916
C GW QRCT C+ PC N G+C Q +C C PG G CE
Sbjct: 173 CCHGWSKAPGSQRCTKP--SCVP-PCQNGGMCLRPQ---LCVCKPGTKGKACETIAAQDT 226
Query: 917 ANPCQNGGS 925
++P G S
Sbjct: 227 SSPVFGGQS 235
Score = 37.7 bits (86), Expect = 0.14
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 11/77 (14%)
Query: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR-PCLNGGTCHMLSR 126
C K CQN G T + D +T+ + PC+NGG C SR
Sbjct: 365 CTKGSCQNS------CEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCS--SR 416
Query: 127 DTYECTCQVGFTGKECQ 143
D +C C FTGK CQ
Sbjct: 417 D--KCQCPPNFTGKLCQ 431
Score = 37.4 bits (85), Expect = 0.18
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 7/39 (17%)
Query: 1305 VDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
V +C +PC+NGG C+ C+CPP F+G CQ
Sbjct: 400 VVIC-HLPCMNGGQCSSRDK------CQCPPNFTGKLCQ 431
Score = 36.6 bits (83), Expect = 0.31
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 18/87 (20%)
Query: 133 CQVGFTGKECQWTDACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDVNECDIPGH 191
C+V T CQ + C G+T T ++ N + LT + V C +P
Sbjct: 361 CKVTCTKGSCQ-------NSCEKGNTTTLISENGHAADTLTATNFR-----VVICHLP-- 406
Query: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYC 218
C +GG C + +CQCP FTG+ C
Sbjct: 407 CMNGGQCSSRD---KCQCPPNFTGKLC 430
Score = 35.8 bits (81), Expect = 0.54
Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 919 PCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNG 961
PCQNGG C+ C+C PG G C+T + S P G
Sbjct: 194 PCQNGGMCL---RPQLCVCKPGTKGKACETIAAQDTSSPVFGG 233
Score = 35.4 bits (80), Expect = 0.70
Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 3/29 (10%)
Query: 1195 PCQNGGTCIDLVNHFKCSCPPGTRGLLCE 1223
PCQNGG C+ C C PGT+G CE
Sbjct: 194 PCQNGGMCL---RPQLCVCKPGTKGKACE 219
Score = 35.0 bits (79), Expect = 0.92
Identities = 31/131 (23%), Positives = 46/131 (35%), Gaps = 16/131 (12%)
Query: 879 SKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSC---------MDG 929
++P + G H G + P G + + + Q+GG + G
Sbjct: 109 ARPAVPGGQLHPNPGGHPAAAPFTKQG---RQVVRSKVPQETQSGGGSRLQVHQKQQLQG 165
Query: 930 VNTFSCLCLPGFT-GDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI 988
VN C G++ Q PC+NGG C + C C+ G G CE
Sbjct: 166 VNVCGGRCCHGWSKAPGSQRCTKPSCVPPCQNGGMC---LRPQLCVCKPGTKGKACETIA 222
Query: 989 NECTESSCFNG 999
+ T S F G
Sbjct: 223 AQDTSSPVFGG 233
Score = 35.0 bits (79), Expect = 0.92
Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 11/80 (13%)
Query: 1348 QVKCRKGEQCVHTASGPRCF----CPSPRDCESGCASSPCQHGGSC-HPQRQPPYYSCQC 1402
QV ++ Q V+ G C P + C PCQ+GG C PQ C C
Sbjct: 156 QVHQKQQLQGVNVCGGRCCHGWSKAPGSQRCTKPSCVPPCQNGGMCLRPQ------LCVC 209
Query: 1403 APPFSGSRCELYTAPPSTPP 1422
P G CE A ++ P
Sbjct: 210 KPGTKGKACETIAAQDTSSP 229
Score = 35.0 bits (79), Expect = 0.92
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 23/103 (22%)
Query: 814 ISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKE-------SPNFESYTCLCAPGWQ 866
+S +T + +T C+ C+ C+N+ C++ S N + L A ++
Sbjct: 345 LSNHTGRIKVVFTPSICKVT---CTKGSCQNS--CEKGNTTTLISENGHAADTLTATNFR 399
Query: 867 GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE 909
C + PCMN G C + C+CPP F+G C+
Sbjct: 400 VVICHL--------PCMNGGQCSSRD---KCQCPPNFTGKLCQ 431
Score = 34.7 bits (78), Expect = 1.2
Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 3/39 (7%)
Query: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNP 803
PCQNGG C + C CK G KG C+ + S+P
Sbjct: 194 PCQNGGMC---LRPQLCVCKPGTKGKACETIAAQDTSSP 229
Score = 34.3 bits (77), Expect = 1.6
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 3/29 (10%)
Query: 1195 PCQNGGTCIDLVNHFKCSCPPGTRGLLCE 1223
PC NGG C + KC CPP G LC+
Sbjct: 406 PCMNGGQCS---SRDKCQCPPNFTGKLCQ 431
Score = 34.3 bits (77), Expect = 1.6
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 4/47 (8%)
Query: 443 ECLKGYAGPR---CEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF 486
ECL GY C+ DINEC + CL+ +G + C C GF
Sbjct: 611 ECLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGF 656
Score = 33.5 bits (75), Expect = 2.7
Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 3/29 (10%)
Query: 540 PCLNGAKCIDHPNGYECQCATGFTGVLCE 568
PC+NG +C +CQC FTG LC+
Sbjct: 406 PCMNGGQCSSRD---KCQCPPNFTGKLCQ 431
Score = 33.1 bits (74), Expect = 3.5
Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 1382 PCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTP 1421
PC +GG C + + CQC P F+G C++ S P
Sbjct: 406 PCMNGGQCSSRDK-----CQCPPNFTGKLCQIPVHGASVP 440
Score = 33.1 bits (74), Expect = 3.5
Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 520 CPPGF---TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP 576
C PG+ CQ DI++C +C++ Y C C GF + +C P
Sbjct: 612 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGP---DPTFSSCVP 667
Query: 577 DP 578
DP
Sbjct: 668 DP 669
Score = 32.7 bits (73), Expect = 4.5
Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 19/123 (15%)
Query: 723 ECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDK-NECLSNPCQNGGTCDNLVNGYRC 781
E + + C G GLS + C G VG + +K +C P +G
Sbjct: 562 ETIGSQC--GKALPGLSKQEDCC--GTVGTSWGFNKCQKCPKKPSYHG-------YNQMM 610
Query: 782 TCKKGFKGYN---CQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCS 838
C G+K N CQ +I+EC G C + + Y C C + G + C
Sbjct: 611 ECLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKI---GFGPDPTFSSCV 666
Query: 839 PNP 841
P+P
Sbjct: 667 PDP 669
Score = 32.3 bits (72), Expect = 5.9
Identities = 22/68 (32%), Positives = 27/68 (39%), Gaps = 16/68 (23%)
Query: 203 GSYQCQCPQGFT-------GQYCDSLY-----VPCAPSPCVNGGTCRQTGDFTFECNCLP 250
GS Q C +G T G D+L V PC+NGG C +C C P
Sbjct: 368 GSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRD----KCQCPP 423
Query: 251 GFEGSTCE 258
F G C+
Sbjct: 424 NFTGKLCQ 431
Score = 32.0 bits (71), Expect = 7.8
Identities = 20/63 (31%), Positives = 24/63 (38%), Gaps = 12/63 (19%)
Query: 1071 PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130
PC N G C + +C CP + G C +P G V L QHS A
Sbjct: 406 PCMNGGQC---SSRDKCQCPPNFTGKLCQIP---------VHGASVPKLYQHSQQPGKAL 453
Query: 1131 NTH 1133
TH
Sbjct: 454 GTH 456
>gi|46249412 latent transforming growth factor beta binding protein 1
isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 233 bits (593), Expect = 2e-60
Identities = 241/854 (28%), Positives = 353/854 (41%), Gaps = 162/854 (18%)
Query: 494 EINECQSNPCV-NNGQCVDKVNRFQCLCPPGFTGPVCQ---IDIDDCSSTPCL-NGAKCI 548
EINEC NP + G C++ R+ C+C G+ Q +DID+C+ L + +C
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
Query: 549 DHPNGYECQCATGFT----GVLCEENIDNC-DPDPCHHGQCQDGIDSYTC-ICNPGY--- 599
+ + C C GF G C + +D C PD C G C + + ++ C C+ GY
Sbjct: 608 NTEGSFLCICPAGFMASEEGTNCID-VDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 666
Query: 600 MGAICSDQIDECYSSPCLNDGRCIDLVNGYQC-NCQPGTSGVNCE-INFDDCAS-NPCIH 656
C D IDEC + D +C++ YQC C G G N + ++ D+C N C +
Sbjct: 667 QRGRCED-IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCAN 725
Query: 657 GICMDGINRYSCVCSPGFTG----QRCNIDIDECASNPCRKGATCINGVNGFRCICPEGP 712
G C + Y C C G+T + C DIDEC C N FRC C +G
Sbjct: 726 GDCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQCKNTEGSFRCTCGQGY 784
Query: 713 HHPSCYSQ---VNECLSNP-CIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNECLSN 764
+ Q ++EC C HG C ++C+CD G+ +G +CE D NECL +
Sbjct: 785 QLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE-DINECLED 843
Query: 765 P--CQNGGTCDNLVNGYRCTCKKGFK---GYNCQVNIDECAS-NPCLNQGTCFDDISGYT 818
CQ G C N Y CTC GF+ CQ +I+EC C QG C + +
Sbjct: 844 KSVCQRGD-CINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECLNTEGSFH 901
Query: 819 CHCVLPYT----GKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRC 870
C C ++ G+ C+ + + C++ C + S+ CLC G+Q GQ C
Sbjct: 902 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAG--SFRCLCYQGFQAPQDGQGC 959
Query: 871 TIDIDEC--ISKPCMNHGLCHNTQGSYMCECPPG---FSGM----------DCEEDID-- 913
+D++EC +S C C N +GS++C C +S M D + D+D
Sbjct: 960 -VDVNECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQP 1017
Query: 914 -----DCLANP--------------------CQNGGSCMDGVNTFSCLCL---------- 938
+C N C +G D F C L
Sbjct: 1018 KEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCP 1077
Query: 939 --PGFT---------GDKCQTDMNECL---SEPCKNGGTCSDYVNSYTCKCQAG--FDGV 982
GF G + D +ECL E CKNG C + Y C C+ G +D V
Sbjct: 1078 KGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQGTYYDPV 1136
Query: 983 HCEN-NINECTESSCFNGGTCVDGINSFSCLC--PVGFTGSF--CLH--EINECSSHPCL 1035
+ +++EC + S G CV+ S++C C P+ S C+ E NE +
Sbjct: 1137 KLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDV 1196
Query: 1036 NEGTCVDGLGT-YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES-QC-LCPSG 1092
+ C + L Y CS PL GK QT C C+ +A QC LCP
Sbjct: 1197 YQDLCWEHLSDEYVCSRPL--VGK--QTTYTECC---------CLYGEAWGMQCALCPLK 1243
Query: 1093 WAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDE 1152
+ Y + N+ + R+ + L S + ++ Q + S+ E Q +E
Sbjct: 1244 DSDDYAQLCNIP--VTGRRQPYGRDALVDFSEQYTPEADPYFIQDR--FLNSFEELQAEE 1299
Query: 1153 CAS-NPCQHGATCSDFIGGYRCECVPGYQ----GVNCEYEVDECQN-----QPCQNGGTC 1202
C N C++G C GY C+C GY + C +V+EC C+N C
Sbjct: 1300 CGILNGCENGR-CVRVQEGYTCDCFDGYHLDTAKMTC-VDVNECDELNNRMSLCKN-AKC 1356
Query: 1203 IDLVNHFKCSCPPG 1216
I+ +KC C PG
Sbjct: 1357 INTDGSYKCLCLPG 1370
Score = 228 bits (582), Expect = 4e-59
Identities = 237/866 (27%), Positives = 348/866 (40%), Gaps = 146/866 (16%)
Query: 181 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTC 236
T++NEC + G C+NLP Y C C +G+ + C + + G C
Sbjct: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
Query: 237 RQTGDFTFECNCLPGF----EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCR-CPP--Q 289
T + +F C C GF EG+ C ++D+C G CV+ V + C C +
Sbjct: 607 ENT-EGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYR 664
Query: 290 WTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCV-CVNGWSG--DDCSENIDDCAFAS 346
T + ED+DEC L P+ C + C N G Y CV C G+ G C + +D+C +
Sbjct: 665 MTQRGRCEDIDEC-LNPSTCPD-EQCVNSPGSYQCVPCTEGFRGWNGQCLD-VDECLEPN 721
Query: 347 CTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALC---DTNPLNGQYICTC 403
C + S+ C C +G H I + C +G LC G + CTC
Sbjct: 722 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDI-DECQQGNLCVNGQCKNTEGSFRCTC 780
Query: 404 PQGYK---GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY----AGPRCEMD 456
QGY+ D ED+DEC + + C H G+C NT+G+F C C +GY G CE D
Sbjct: 781 GQGYQLSAAKDQCEDIDEC--QHRHLCAH-GQCRNTEGSFQCVCDQGYRASGLGDHCE-D 836
Query: 457 INECHSDP--CQNDATCLDKIGGFTCLCMPGFK---GVHCELEINECQ-SNPCVNNGQCV 510
INEC D CQ C++ G + C C GF+ C+ +INEC+ C G+C+
Sbjct: 837 INECLEDKSVCQR-GDCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECL 894
Query: 511 DKVNRFQCLCPPGFT----GPVCQIDIDDC-SSTPCLNGAKCIDHPNGYECQCATGF--- 562
+ F C+C GF+ G C+ DID+C ++T C + C + + C C GF
Sbjct: 895 NTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 953
Query: 563 -TGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCIC---NPGY--MGAIC---------- 604
G C + ++ C+ C C++ S+ C+C N Y M C
Sbjct: 954 QDGQGCVD-VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV 1012
Query: 605 -----SDQIDECYSSPCLNDGRCID-----LVNGYQCNCQPGTS-GVNCEINFDDCASNP 653
++ ECY + LND D V +C C G G NCEI
Sbjct: 1013 DVDQPKEEKKECYYN--LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTA 1070
Query: 654 CIHGICMDGINRYSCVCSPGFTGQRCNIDIDEC---ASNPCRKGATCINGVNGFRCICPE 710
+C G S G D DEC C+ G C+N G+ C C +
Sbjct: 1071 EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQ 1129
Query: 711 GPHHP----SCYSQVNECLS-NPCIHGNCTGGLSGYKCLC------DAGWVGINCEVDKN 759
G ++ C+ ++EC + CI G C Y C C DA + N
Sbjct: 1130 GTYYDPVKLQCF-DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESN 1188
Query: 760 ECLSNPCQNGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCF------- 811
E + C ++L + Y C+ K Q EC C G +
Sbjct: 1189 EQIEETDVYQDLCWEHLSDEYVCSRPLVGK----QTTYTEC----CCLYGEAWGMQCALC 1240
Query: 812 --DDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQR 869
D Y C +P TG+ P A+ S E YT P + R
Sbjct: 1241 PLKDSDDYAQLCNIPVTGRR----------QPYGRDALVDFS---EQYTPEADPYFIQDR 1287
Query: 870 CTIDIDECISKPC-----MNHGLCHNTQGSYMCECPPGF----SGMDCEEDIDDC----- 915
+E ++ C +G C Q Y C+C G+ + M C D+++C
Sbjct: 1288 FLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTC-VDVNECDELNN 1346
Query: 916 LANPCQNGGSCMDGVNTFSCLCLPGF 941
+ C+N C++ ++ CLCLPG+
Sbjct: 1347 RMSLCKN-AKCINTDGSYKCLCLPGY 1371
Score = 213 bits (542), Expect = 2e-54
Identities = 232/868 (26%), Positives = 338/868 (38%), Gaps = 186/868 (21%)
Query: 298 DVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSE---NIDDCAFAS--CTPGST 352
+++EC + P+ C G C N Y C+C G+ + +ID+C C+ G
Sbjct: 548 EINECTVNPDIC-GAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR- 605
Query: 353 CIDRVASFSCMCPEG----KAGLLCHLDDACIS-NPCHKGALCDTNPLNGQYICT-CPQG 406
C + SF C+CP G + G C D C+ + C +G +T G + C C G
Sbjct: 606 CENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTV---GAFRCEYCDSG 662
Query: 407 YKGADC--TEDVDECAMANSNPCEHAGKCVNTDGAFHC-ECLKGYAGPRCE-MDINECHS 462
Y+ ED+DEC ++ P E +CVN+ G++ C C +G+ G + +D++EC
Sbjct: 663 YRMTQRGRCEDIDECLNPSTCPDE---QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE 719
Query: 463 DPCQNDATCLDKIGGFTCLCMPGFKGV----HCELEINECQSNPCVNNGQCVDKVNRFQC 518
+ C + G + C C G+ HC +I+ECQ NGQC + F+C
Sbjct: 720 PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQCKNTEGSFRC 778
Query: 519 LCPPGF----TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFT----GVLCEEN 570
C G+ C+ DID+C +C + ++C C G+ G CE+
Sbjct: 779 TCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED- 836
Query: 571 IDNC--DPDPCHHGQCQDGIDSYTCICNPGYM---GAICSDQIDEC-YSSPCLNDGRCID 624
I+ C D C G C + SY C C G+ C D I+EC + C G C++
Sbjct: 837 INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQD-INECEHPGLCGPQGECLN 895
Query: 625 LVNGYQCNCQPGTS----GVNCEINFDDCASNPCI--HGICMDGINRYSCVCSPGFT--- 675
+ C CQ G S G CE + D+C +N HG C + + C+C GF
Sbjct: 896 TEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ 954
Query: 676 -GQRCNIDIDECA--SNPCRKGATCINGVNGFRCICPE-----GPHHPSCYSQVN----- 722
GQ C +D++EC S C + A C N F C+C + P C S+ +
Sbjct: 955 DGQGC-VDVNECELLSGVCGE-AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV 1012
Query: 723 ----------ECLSNPCIHGNCTGGLSG----YKCLCD--AGWVGINCEV---------- 756
EC N C L+ +C C AGW G NCE+
Sbjct: 1013 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGW-GDNCEIFPCPVLGTAE 1071
Query: 757 ---------------------------DKNECL---SNPCQNGGTCDNLVNGYRCTCKKG 786
D +ECL C+NG C N GY C CK+G
Sbjct: 1072 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG-FCLNTRPGYECYCKQG 1130
Query: 787 --FKGYNCQV-NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCE 843
+ Q ++DEC G C + Y C C P ++ S C
Sbjct: 1131 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHP--------MVLDASEKRCI 1182
Query: 844 NAAVCKES-PNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPG 902
A E + Y LC W+ + + S+P + + C C G
Sbjct: 1183 RPAESNEQIEETDVYQDLC---WEH----LSDEYVCSRPLVGKQTTYTE-----CCCLYG 1230
Query: 903 FS-GMDCE----EDIDDC--LANPCQNG-------GSCMDGVNTFSCLCLPGFTGDKCQT 948
+ GM C +D DD L N G + +D ++ P F D+
Sbjct: 1231 EAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLN 1290
Query: 949 DMNECLSEPCK--NG---GTCSDYVNSYTCKCQAGFDGVHCEN------NINECTE---- 993
E +E C NG G C YTC C FDG H + ++NEC E
Sbjct: 1291 SFEELQAEECGILNGCENGRCVRVQEGYTCDC---FDGYHLDTAKMTCVDVNECDELNNR 1347
Query: 994 -SSCFNGGTCVDGINSFSCLCPVGFTGS 1020
S C N C++ S+ CLC G+ S
Sbjct: 1348 MSLCKNA-KCINTDGSYKCLCLPGYVPS 1374
Score = 199 bits (505), Expect = 4e-50
Identities = 175/647 (27%), Positives = 264/647 (40%), Gaps = 103/647 (15%)
Query: 715 PSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGWVGINCE---VDKNEC--LSNPCQ 767
P+ +++NEC NP C G+C Y C+C G+ + VD +EC + + C
Sbjct: 543 PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 602
Query: 768 NGGTCDNLVNGYRCTCKKGF----KGYNCQVNIDECASNPCLNQGTCFDDISGYTC-HCV 822
G C+N + C C GF +G NC +++DEC +G C + + + C +C
Sbjct: 603 Q-GRCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCD 660
Query: 823 LPY---TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCL-CAP---GWQGQRCTIDID 875
Y C+ + +P+ C + C SP SY C+ C GW GQ +D+D
Sbjct: 661 SGYRMTQRGRCEDIDECLNPSTCPDEQ-CVNSPG--SYQCVPCTEGFRGWNGQ--CLDVD 715
Query: 876 ECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEE---DIDDC-LANPCQNGGSCMDGVN 931
EC+ +G C N +GSYMC C G++ + DID+C N C N G C +
Sbjct: 716 ECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN-GQCKNTEG 774
Query: 932 TFSCLCLPGF----TGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFD----GVH 983
+F C C G+ D+C+ D++EC G C + S+ C C G+ G H
Sbjct: 775 SFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDH 833
Query: 984 CENNINECTE-SSCFNGGTCVDGINSFSCLCPVGF--TGSFCLHEINECSSHP--CLNEG 1038
CE +INEC E S G C++ S+ C CP GF + +INEC HP C +G
Sbjct: 834 CE-DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQG 891
Query: 1039 TCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWA 1094
C++ G++ C C G++ G+ C+ + + + C + G C +CLC G+
Sbjct: 892 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ 951
Query: 1095 GAYCDVPNVSCDIAASRRGVLVEHLCQH---SGVCINAGNTHYCQCPLGYTGSYCEEQLD 1151
V + GV E C++ S +C+ A G S LD
Sbjct: 952 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD 1011
Query: 1152 ECASNPCQHGATC--------------SDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQ 1197
P + C + + C C G D C+ PC
Sbjct: 1012 VDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGW------GDNCEIFPCP 1065
Query: 1198 NGGTCIDLVNHFKCSCPPGTRGLLCEE-----------NIDDCAR-GPHCLNGGQCMDRI 1245
GT F CP G + E + D+C G G C++
Sbjct: 1066 VLGTA-----EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTR 1120
Query: 1246 GGYSCRCLPG----------FAGERCEGDINECLSNPC-SSEGSLDC 1281
GY C C G F + C+ D + C+ C ++EGS +C
Sbjct: 1121 PGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNC 1166
Score = 191 bits (485), Expect = 8e-48
Identities = 224/825 (27%), Positives = 314/825 (38%), Gaps = 187/825 (22%)
Query: 89 TCRCASGFTGEDCQYSTSH--PCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE----C 142
TC C G+ + Q C + + G C + ++ C C GF E C
Sbjct: 572 TCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN-TEGSFLCICPAGFMASEEGTNC 630
Query: 143 QWTDACLSHPCANGSTCTTVANQFSCK-CLTGFTGQ---KCETDVNECDIPGHCQHGGTC 198
D CL C F C+ C +G+ +CE D++EC P C C
Sbjct: 631 IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCE-DIDECLNPSTCPDE-QC 688
Query: 199 LNLPGSYQC-QCPQGFTGQYCDSLYVP--CAPSPCVNGGTCRQTGDFTFECNCLPGFEGS 255
+N PGSYQC C +GF G L V P+ C NG G + C+C G+ +
Sbjct: 689 VNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYM--CSCHKGYTRT 746
Query: 256 TCERNIDDCPNHRCQNGGVCVDGV-----NTYNCRCPPQW---TGQFCTEDVDECLLQPN 307
++ D CQ G +CV+G ++ C C + + ED+DEC + +
Sbjct: 747 PDHKHCRDIDE--CQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHR-H 803
Query: 308 ACQNGGTCANRNGGYGCVCVNGWS----GDDCSENIDDCAF--ASCTPGSTCIDRVASFS 361
C +G C N G + CVC G+ GD C E+I++C + C G CI+ S+
Sbjct: 804 LCAHG-QCRNTEGSFQCVCDQGYRASGLGDHC-EDINECLEDKSVCQRGD-CINTAGSYD 860
Query: 362 CMCPEGKAGLLCHLDD--ACIS-NPCHKGALCDTNP----LNGQYICTCPQGYK----GA 410
C CP+G LDD C N C LC G + C C QG+ G
Sbjct: 861 CTCPDG-----FQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 915
Query: 411 DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPR----CEMDINECH--SDP 464
C ED+DEC N+ C+ G C NT G+F C C +G+ P+ C +D+NEC S
Sbjct: 916 TC-EDIDECV--NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC-VDVNECELLSGV 971
Query: 465 CQNDATCLDKIGGFTCLC---------------------------MPGFKGVHCELEINE 497
C +A C + G F C+C P + C +N+
Sbjct: 972 C-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLND 1030
Query: 498 C-------------QSNPCVNNGQCVDKVNRFQC----------LCPPGF---------- 524
Q C + D F C +CP G
Sbjct: 1031 ASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSS 1090
Query: 525 -TGPVCQIDIDDC---SSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDNC-D 575
G D D+C C NG C++ GYEC C G + C + +D C D
Sbjct: 1091 EAGGENYKDADECLLFGQEICKNGF-CLNTRPGYECYCKQGTYYDPVKLQCFD-MDECQD 1148
Query: 576 PDPCHHGQCQDGIDSYTCIC-NPGYMGAI---------CSDQIDEC--YSSPC---LNDG 620
P C GQC + SY C C +P + A ++QI+E Y C L+D
Sbjct: 1149 PSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDE 1208
Query: 621 R-CIDLVNGYQ-----CNCQPGTS-GVNCEI----NFDDCAS----------NPCIHGIC 659
C + G Q C C G + G+ C + + DD A P
Sbjct: 1209 YVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDAL 1268
Query: 660 MDGINRYSCVCSPGFTGQRC-----NIDIDECAS-NPCRKGATCINGVNGFRCICPEGPH 713
+D +Y+ P F R + +EC N C G C+ G+ C C +G H
Sbjct: 1269 VDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR-CVRVQEGYTCDCFDGYH 1327
Query: 714 HPSCYS---QVNEC--LSNP---CIHGNCTGGLSGYKCLCDAGWV 750
+ VNEC L+N C + C YKCLC G+V
Sbjct: 1328 LDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1372
Score = 167 bits (423), Expect = 1e-40
Identities = 138/460 (30%), Positives = 202/460 (43%), Gaps = 59/460 (12%)
Query: 873 DIDECISKPCM-NHGLCHNTQGSYMCECPPGFSGMDCEE---DIDDC--LANPCQNGGSC 926
+I+EC P + G C N Y C C G+ + + DID+C + + C G C
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG-RC 606
Query: 927 MDGVNTFSCLCLPGFTGDKCQT---DMNECLSEPCKNGGTCSDYVNSYTCK-CQAGFDGV 982
+ +F C+C GF + T D++ECL G C + V ++ C+ C +G+
Sbjct: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 666
Query: 983 H---CENNINECTESSCFNGGTCVDGINSFSCL-CPVGFTG--SFCLHEINECSSHPCLN 1036
CE+ I+EC S CV+ S+ C+ C GF G CL +++EC
Sbjct: 667 QRGRCED-IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL-DVDECLEPNVCA 724
Query: 1037 EGTCVDGLGTYRCSCPLGYTG----KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSG 1092
G C + G+Y CSC GYT K+C+ + + C N G C + +C C G
Sbjct: 725 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN-GQCKNTEGSFRCTCGQG 783
Query: 1093 WAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT----GSYCEE 1148
+ + D R HLC H G C N + C C GY G +CE+
Sbjct: 784 YQLSAAKDQCEDIDECQHR------HLCAH-GQCRNTEGSFQCVCDQGYRASGLGDHCED 836
Query: 1149 QLDECASNP--CQHGATCSDFIGGYRCECVPGYQ---GVNCEYEVDECQNQP-CQNGGTC 1202
++EC + CQ G C + G Y C C G+Q C+ +++EC++ C G C
Sbjct: 837 -INECLEDKSVCQRG-DCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGEC 893
Query: 1203 IDLVNHFKCSCPPG----TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA- 1257
++ F C C G G CE+ ID+C C + G C + G + C C GF
Sbjct: 894 LNTEGSFHCVCQQGFSISADGRTCED-IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA 952
Query: 1258 ---GERCEGDINEC--LSNPCSSEGSLDCIQLTNDYLCVC 1292
G+ C D+NEC LS C G C + +LCVC
Sbjct: 953 PQDGQGCV-DVNECELLSGVC---GEAFCENVEGSFLCVC 988
Score = 162 bits (411), Expect = 3e-39
Identities = 133/441 (30%), Positives = 193/441 (43%), Gaps = 64/441 (14%)
Query: 948 TDMNECLSEPCKNG-GTCSDYVNSYTCKCQAGFDGVHCEN---NINECTE-SSCFNGGTC 1002
T++NEC P G G C + YTC C G+ + +I+ECT+ + G C
Sbjct: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
Query: 1003 VDGINSFSCLCPVGFT----GSFCLHEINECSSHPCLNEGTCVDGLGTYRCS-CPLGYTG 1057
+ SF C+CP GF G+ C+ +++EC EG CV+ +G +RC C GY
Sbjct: 607 ENTEGSFLCICPAGFMASEEGTNCI-DVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRM 665
Query: 1058 KN---CQTLVNLCSRSPCKNKGTCVQKKAESQCL-CPSG---WAGAYCDVPNVSCDIAAS 1110
C+ + + S C ++ CV QC+ C G W G DV
Sbjct: 666 TQRGRCEDIDECLNPSTCPDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC------- 717
Query: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS----YCEEQLDECAS-NPCQHGATCS 1165
L ++C + G C N ++ C C GYT + +C + +DEC N C +G C
Sbjct: 718 ----LEPNVCAN-GDCSNLEGSYMCSCHKGYTRTPDHKHCRD-IDECQQGNLCVNGQ-CK 770
Query: 1166 DFIGGYRCECVPGYQ----GVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR--- 1218
+ G +RC C GYQ CE ++DECQ++ G C + F+C C G R
Sbjct: 771 NTEGSFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASG 829
Query: 1219 -GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA---GERCEGDINECLSNP-- 1272
G CE+ I++C G C++ G Y C C GF + C+ DINEC +P
Sbjct: 830 LGDHCED-INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQ-DINEC-EHPGL 886
Query: 1273 CSSEGSLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMPCLNGGTCAVASNMPDG 1328
C +G +C+ + CVC+ F+ GR CE + C + G C N
Sbjct: 887 CGPQG--ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFC---DNTAGS 941
Query: 1329 FICRCPPGFSGARCQSSCGQV 1349
F C C GF + C V
Sbjct: 942 FRCLCYQGFQAPQDGQGCVDV 962
Score = 155 bits (391), Expect = 6e-37
Identities = 195/735 (26%), Positives = 281/735 (38%), Gaps = 174/735 (23%)
Query: 27 QCRDGYEPCVNEGMC----VTYHNGTGYC-KCPEGFLG--EYCQHRDPC-EKNRCQNGGT 78
+C D + C+N C G+ C C EGF G C D C E N C NG
Sbjct: 670 RCED-IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD- 727
Query: 79 CVAQAMLGKATCRCASGFTGE-DCQYSTS-HPCFVSRPCLNGGTCHMLSRDTYECTCQVG 136
+ G C C G+T D ++ C C+NG + + ++ CTC G
Sbjct: 728 --CSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN--TEGSFRCTCGQG 783
Query: 137 F----TGKECQWTDACLS-HPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNEC- 186
+ +C+ D C H CA+G C F C C G+ G CE D+NEC
Sbjct: 784 YQLSAAKDQCEDIDECQHRHLCAHGQ-CRNTEGSFQCVCDQGYRASGLGDHCE-DINECL 841
Query: 187 DIPGHCQHGGTCLNLPGSYQCQCPQGFT---GQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
+ CQ G C+N GSY C CP GF + C + P C G C T + +
Sbjct: 842 EDKSVCQRGD-CINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNT-EGS 899
Query: 244 FECNCLPGF----EGSTCERNIDDCPNHR-CQNGGVCVDGVNTYNCRC-----PPQWTGQ 293
F C C GF +G TCE +ID+C N+ C + G C + ++ C C PQ GQ
Sbjct: 900 FHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ-DGQ 957
Query: 294 FCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNG--------------WSGD------ 333
C DV+EC L C C N G + CVC + S D
Sbjct: 958 GCV-DVNECELLSGVCGEA-FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVD 1015
Query: 334 -------DCSENIDDCAFAS-------------CTPGSTCIDRVASFSC----------M 363
+C N++D + CT G+ D F C M
Sbjct: 1016 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM 1075
Query: 364 CPEGK-----------AGLLCHLD-DACI---SNPCHKGALCDTNPLNGQYICTCPQGYK 408
CP+GK AG + D D C+ C G +T P Y C C QG
Sbjct: 1076 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRP---GYECYCKQGTY 1132
Query: 409 ----GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC----LKGYAGPRC------- 453
C D+DEC +S C G+CVNT+G+++C C + + RC
Sbjct: 1133 YDPVKLQCF-DMDECQDPSS--CID-GQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESN 1188
Query: 454 -EMDINECHSDPC----QNDATCLDKIGG-----FTCLCMPGFK-GVHCEL-------EI 495
+++ + + D C ++ C + G C C+ G G+ C L +
Sbjct: 1189 EQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDY 1248
Query: 496 NECQSNPCVNNGQ------CVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC--LNGA-- 545
+ + P Q VD ++ P F ++ + C LNG
Sbjct: 1249 AQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCEN 1308
Query: 546 -KCIDHPNGYECQCATGF---TGVLCEENIDNCDP-----DPCHHGQCQDGIDSYTCICN 596
+C+ GY C C G+ T + +++ CD C + +C + SY C+C
Sbjct: 1309 GRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCL 1368
Query: 597 PGYMGAICSDQIDEC 611
PGY + SD+ + C
Sbjct: 1369 PGY---VPSDKPNYC 1380
Score = 147 bits (371), Expect = 1e-34
Identities = 165/721 (22%), Positives = 270/721 (37%), Gaps = 132/721 (18%)
Query: 27 QCRDGYEPCVNEGMCVTYH----NGTGYCKCPEGFLG----EYCQHRDPCEK-NRCQNGG 77
QC D + C+ +C G+ C C +G+ ++C+ D C++ N C NG
Sbjct: 710 QCLD-VDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQ 768
Query: 78 TCVAQAMLGKATCRCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQV 135
+ G C C G+ + Q C C +G + + +++C C
Sbjct: 769 CKNTE---GSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRN--TEGSFQCVCDQ 823
Query: 136 GFT----GKECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFTGQKCET--DVNECD 187
G+ G C+ + CL C G C A + C C GF +T D+NEC+
Sbjct: 824 GYRASGLGDHCEDINECLEDKSVCQRGD-CINTAGSYDCTCPDGFQLDDNKTCQDINECE 882
Query: 188 IPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
PG C G CLN GS+ C C QGF+ G+ C+ + + C + G C T +
Sbjct: 883 HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAG-S 941
Query: 244 FECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECL 303
F C C GF+ Q+G CV DV+EC
Sbjct: 942 FRCLCYQGFQAP--------------QDGQGCV---------------------DVNECE 966
Query: 304 LQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID--RVASFS 361
L C C N G + CVC + + S C + T +D +
Sbjct: 967 LLSGVC-GEAFCENVEGSFLCVCAD--ENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKE 1023
Query: 362 CMCPEGKAGLLCHL-------DDACISNPCHKGALCDTNPL----NGQYICTCPQG---- 406
C A L ++ + C ++ G C+ P ++ CP+G
Sbjct: 1024 CYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFV 1083
Query: 407 -------YKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKG-YAGP---RCEM 455
G + +D DEC + C++ G C+NT + C C +G Y P +C
Sbjct: 1084 PAGESSSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQGTYYDPVKLQC-F 1141
Query: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNR 515
D++EC D C++ G + C C L+ +E + + + +++ +
Sbjct: 1142 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPM-----VLDASEKRCIRPAESNEQIEETDV 1196
Query: 516 FQCLCPPGFTGP-VCQIDI--DDCSSTPCLNGAKCIDHPNGYECQCA------TGFTGVL 566
+Q LC + VC + + T C C + + QCA + L
Sbjct: 1197 YQDLCWEHLSDEYVCSRPLVGKQTTYTEC-----CCLYGEAWGMQCALCPLKDSDDYAQL 1251
Query: 567 CEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC-----LNDGR 621
C + P D + YT +P ++ + +E + C +GR
Sbjct: 1252 CNIPVTG-RRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR 1310
Query: 622 CIDLVNGYQCNCQPG----TSGVNC-EINFDDCASNP---CIHGICMDGINRYSCVCSPG 673
C+ + GY C+C G T+ + C ++N D +N C + C++ Y C+C PG
Sbjct: 1311 CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1370
Query: 674 F 674
+
Sbjct: 1371 Y 1371
Score = 102 bits (255), Expect = 4e-21
Identities = 107/402 (26%), Positives = 150/402 (37%), Gaps = 94/402 (23%)
Query: 1123 SGVCINAGNTHYCQCPLGYTGSYCEEQ---LDECAS--NPCQHGATCSDFIGGYRCECVP 1177
+G CIN + C C GY S + + +DEC + C G C + G + C C
Sbjct: 561 AGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR-CENTEGSFLCICPA 619
Query: 1178 GY----QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCS-CPPG---TRGLLCEENIDDC 1229
G+ +G NC +VDEC G C++ V F+C C G T+ CE+ ID+C
Sbjct: 620 GFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCED-IDEC 677
Query: 1230 ARGPHCLNGGQCMDRIGGYSC-RCLPGFAGERCEG-DINECLSNPCSSEGSLDCIQLTND 1287
C + QC++ G Y C C GF G + D++ECL + G DC L
Sbjct: 678 LNPSTCPDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANG--DCSNLEGS 734
Query: 1288 YLCVCRSAFT----GRHCETFVDVCPQ-MPCLNGG----------TC------------- 1319
Y+C C +T +HC +D C Q C+NG TC
Sbjct: 735 YMCSCHKGYTRTPDHKHCRD-IDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQC 793
Query: 1320 --------------AVASNMPDGFICRCPPGFSGARCQSSCGQVK--------CRKGEQC 1357
N F C C G+ + C + C++G+ C
Sbjct: 794 EDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGD-C 852
Query: 1358 VHTASGPRCFCPS--PRDCESGCAS-SPCQHGGSCHPQRQ----PPYYSCQCAPPFS--- 1407
++TA C CP D C + C+H G C PQ + + C C FS
Sbjct: 853 INTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISA 912
Query: 1408 -GSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHAC 1448
G CE C++ D G CD S C
Sbjct: 913 DGRTCE--------DIDECVNNTVCDS--HGFCDNTAGSFRC 944
Score = 55.1 bits (131), Expect = 9e-07
Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 13/119 (10%)
Query: 808 GTCFDDISGYTCHCVLPYTGKN---CQTVLAPCSPNPCENAAVCKESPNFESYTCL--CA 862
G CF + G C LP K C TV N C+ C + P++ Y + C
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQK---CPKKPSYHGYNQMMECL 287
Query: 863 PGWQGQRCTI--DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP 919
PG++ T DI+EC + +G C NT GSY C C GF + C+ +P
Sbjct: 288 PGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGP---DPTFSSCVPDP 343
Score = 52.0 bits (123), Expect = 7e-06
Identities = 53/196 (27%), Positives = 77/196 (39%), Gaps = 26/196 (13%)
Query: 1264 DINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMPCL-NGGT 1318
+INEC NP G+ CI L Y C+C + R C +D C Q+ L + G
Sbjct: 548 EINECTVNPDIC-GAGHCINLPVRYTCICYEGYRFSEQQRKCVD-IDECTQVQHLCSQGR 605
Query: 1319 CAVASNMPDGFICRCPPGFSGARCQSSCGQVK-------CRKGEQCVHTASGPRC-FCPS 1370
C N F+C CP GF + ++C V C +G CV+T RC +C S
Sbjct: 606 C---ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEG-HCVNTVGAFRCEYCDS 661
Query: 1371 P-RDCESGCAS--SPCQHGGSCHPQR---QPPYYSC-QCAPPFSGSRCELYTAPPSTPPA 1423
R + G C + +C ++ P Y C C F G + P
Sbjct: 662 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN 721
Query: 1424 TCLSQYCADKARDGVC 1439
C + C++ +C
Sbjct: 722 VCANGDCSNLEGSYMC 737
Score = 45.8 bits (107), Expect = 5e-04
Identities = 36/112 (32%), Positives = 44/112 (39%), Gaps = 24/112 (21%)
Query: 429 HAG--KCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIG-GFTCLCMPG 485
H G K V T C KG CE N T + + G L
Sbjct: 22 HTGRIKVVFTPSICKVTCTKGSCQNSCEKG----------NTTTLISENGHAADTLTATN 71
Query: 486 FKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCS 537
F+ V C L PC+N GQC +R +C CPP FTG +CQI + S
Sbjct: 72 FRVVICHL--------PCMNGGQCS---SRDKCQCPPNFTGKLCQIPVHGAS 112
Score = 45.8 bits (107), Expect = 5e-04
Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 8/66 (12%)
Query: 169 KCLTGF---TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC 225
+CL G+ C+ D+NEC + G C +G CLN GSY+C C GF D + C
Sbjct: 285 ECLPGYKRVNNTFCQ-DINECQLQGVCPNG-ECLNTMGSYRCTCKIGFGP---DPTFSSC 339
Query: 226 APSPCV 231
P P V
Sbjct: 340 VPDPPV 345
Score = 45.4 bits (106), Expect = 7e-04
Identities = 82/359 (22%), Positives = 126/359 (35%), Gaps = 80/359 (22%)
Query: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDG--LGTYRC---- 1049
C NGG C + C CP FTG C ++ S P L + + G LGT+
Sbjct: 81 CMNGGQCS---SRDKCQCPPNFTGKLCQIPVHGASV-PKLYQHSQQPGKALGTHVIHSTH 136
Query: 1050 SCPLGYTG------KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAG--AYCDVP 1101
+ PL T K +VN+ + P + VQ S+ P+G A
Sbjct: 137 TLPLTVTSQQGVKVKFPPNIVNIHVKHPPE---ASVQIHQVSRIDGPTGQKTKEAQPGQS 193
Query: 1102 NVSCDIAASRRGVLVEHLCQHSGVCIN----AGNTHYCQCPLGYTGSYCEEQL------D 1151
VS ++ + H V + A T +C GS C + L +
Sbjct: 194 QVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQE 253
Query: 1152 ECAS--------NPCQHGATCSDFIG-GYRCECVPGYQGVNCEY--EVDECQNQPCQNGG 1200
+C N CQ + G EC+PGY+ VN + +++ECQ Q G
Sbjct: 254 DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNG 313
Query: 1201 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLN--GGQCMDRIGGYSCRCLPGFAG 1258
C++ + ++C+C G + C P ++ G C + +G
Sbjct: 314 ECLNTMGSYRCTCKIGFGP---DPTFSSCVPDPPVISEEKGPCYRLVS----------SG 360
Query: 1259 ERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE--------TFVDVCP 1309
+C +P S + LT C G HCE F ++CP
Sbjct: 361 RQC--------MHPLS-------VHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICP 404
Score = 42.0 bits (97), Expect = 0.007
Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 5/49 (10%)
Query: 482 CMPGFKGVH---CELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGP 527
C+PG+K V+ C+ +INECQ NG+C++ + ++C C GF GP
Sbjct: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGF-GP 332
Score = 40.8 bits (94), Expect = 0.017
Identities = 38/148 (25%), Positives = 56/148 (37%), Gaps = 22/148 (14%)
Query: 574 CDPDPCHHGQCQDGIDSYTCICNPGYM---GAICSDQIDECYSSPCLNDGRCIDLVNGYQ 630
C P +HG Q C PGY C D I+EC +G C++ + Y+
Sbjct: 271 CPKKPSYHGYNQ------MMECLPGYKRVNNTFCQD-INECQLQGVCPNGECLNTMGSYR 323
Query: 631 CNCQPGTSGVNCEINFDDCASNPCI----HGICMDGINR-YSCV--CSPGFTGQRCNIDI 683
C C+ G + F C +P + G C ++ C+ S T Q C +
Sbjct: 324 CTCK---IGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV 380
Query: 684 DECASNPCRKGATCINGVNGFRCICPEG 711
+ C K + G F+ ICP G
Sbjct: 381 GKAWGPHCEK--CPLPGTAAFKEICPGG 406
Score = 39.7 bits (91), Expect = 0.037
Identities = 82/350 (23%), Positives = 118/350 (33%), Gaps = 78/350 (22%)
Query: 66 DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDC---QYSTSHPC--FVSRPCLNGGT 120
D CE C GT M K +G + + Y + C F C NG
Sbjct: 1057 DNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFC 1116
Query: 121 CHMLSRDTYECTCQVG----------FTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
+ +R YEC C+ G F ECQ +C+ C N ++C C
Sbjct: 1117 LN--TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVN------TEGSYNCFC 1168
Query: 171 ----LTGFTGQKC-----------ETDVNE------------CDIP--GHCQHGGTCLNL 201
+ + ++C ETDV + C P G C L
Sbjct: 1169 THPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCL 1228
Query: 202 PGS---YQCQ-CPQGFTGQYCDSLYVPCAP--SPCVNGGTCRQTGDFTFECN---CLPGF 252
G QC CP + Y +P P + +T E + F
Sbjct: 1229 YGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRF 1288
Query: 253 EGSTCERNIDDCPN-HRCQNGGVCVDGVNTYNCRCPPQW---TGQFCTEDVDECLLQPNA 308
S E ++C + C+NG CV Y C C + T + DV+EC N
Sbjct: 1289 LNSFEELQAEECGILNGCENGR-CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNR 1347
Query: 309 ---CQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID 355
C+N C N +G Y C+C+ G+ D CTP +T ++
Sbjct: 1348 MSLCKNA-KCINTDGSYKCLCLPGYVPSDKPN--------YCTPLNTALN 1388
Score = 38.9 bits (89), Expect = 0.063
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 13/87 (14%)
Query: 382 NPCHKGALCDTNPLNGQY--ICTCPQGYKGADCT--EDVDECAMANSNPCEHAGKCVNTD 437
N C K C P Y + C GYK + T +D++EC + P G+C+NT
Sbjct: 266 NKCQK---CPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCP---NGECLNTM 319
Query: 438 GAFHCECLKGYAGPRCEMDINECHSDP 464
G++ C C G+ GP + + C DP
Sbjct: 320 GSYRCTCKIGF-GP--DPTFSSCVPDP 343
Score = 38.5 bits (88), Expect = 0.083
Identities = 82/349 (23%), Positives = 117/349 (33%), Gaps = 75/349 (21%)
Query: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQ-----GTCFDDISGYTC 819
PC NGG C + +C C F G CQ+ + AS P L Q G ++
Sbjct: 80 PCMNGGQCSSRD---KCQCPPNFTGKLCQIPVHG-ASVPKLYQHSQQPGKALGTHVIHST 135
Query: 820 HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECIS 879
H LP T + Q V PN + + + G GQ+ T + S
Sbjct: 136 H-TLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQK-TKEAQPGQS 193
Query: 880 K------PCMNHGLCHNT-----------------------QGSYMCECPPGFSGMDCEE 910
+ P H+T Q + +C G+ +E
Sbjct: 194 QVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQE 253
Query: 911 DIDDCLA-----NPCQNGGS--CMDGVNTFSCLCLPGF---TGDKCQTDMNECLSEPCKN 960
D + N CQ G N CLPG+ CQ D+NEC +
Sbjct: 254 DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMM-ECLPGYKRVNNTFCQ-DINECQLQGVCP 311
Query: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCF--------NGGTCVDGINS-FSC 1011
G C + + SY C C+ GF + T SSC G C ++S C
Sbjct: 312 NGECLNTMGSYRCTCKIGFG--------PDPTFSSCVPDPPVISEEKGPCYRLVSSGRQC 363
Query: 1012 LCP--VGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCP--LGYT 1056
+ P V T C + + C E + G ++ CP +GYT
Sbjct: 364 MHPLSVHLTKQLCCCSVGKAWGPHC--EKCPLPGTAAFKEICPGGMGYT 410
Score = 38.5 bits (88), Expect = 0.083
Identities = 56/257 (21%), Positives = 94/257 (36%), Gaps = 48/257 (18%)
Query: 152 PCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP---GHCQHGGTCL--------- 199
PC NG C++ + C+C FTG+ C+ V+ +P H Q G L
Sbjct: 80 PCMNGGQCSS---RDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTH 136
Query: 200 NLPGSYQCQCPQGFTGQY---CDSLYVPCAPSPCVNGGTCRQ----TGDFTFECNCLPG- 251
LP + Q QG ++ +++V P V + TG T E PG
Sbjct: 137 TLPLTVTSQ--QGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQ--PGQ 192
Query: 252 ----FEGSTCER--NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQ 305
++G ++ I +H+ V T RC + G C + + Q
Sbjct: 193 SQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQ 252
Query: 306 PNACQNGGT---------CANRNGGYG----CVCVNGWS--GDDCSENIDDCAFASCTPG 350
+ C GT C + +G C+ G+ + ++I++C P
Sbjct: 253 EDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPN 312
Query: 351 STCIDRVASFSCMCPEG 367
C++ + S+ C C G
Sbjct: 313 GECLNTMGSYRCTCKIG 329
Score = 38.5 bits (88), Expect = 0.083
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 22/81 (27%)
Query: 708 CPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC-LSNPC 766
CP+ P + Y+Q+ ECL GYK + + C+ D NEC L C
Sbjct: 271 CPKKPSYHG-YNQMMECLP-------------GYKRVNNTF-----CQ-DINECQLQGVC 310
Query: 767 QNGGTCDNLVNGYRCTCKKGF 787
NG C N + YRCTCK GF
Sbjct: 311 PNG-ECLNTMGSYRCTCKIGF 330
Score = 38.5 bits (88), Expect = 0.083
Identities = 42/129 (32%), Positives = 50/129 (38%), Gaps = 31/129 (24%)
Query: 294 FCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPG--- 350
FC +D++EC LQ C NG C N G Y C C G+ D F+SC P
Sbjct: 297 FC-QDINECQLQ-GVCPNG-ECLNTMGSYRCTCKIGFGPDP--------TFSSCVPDPPV 345
Query: 351 -----STCIDRVAS-FSCMCPEGKAGLLCHLDD--ACISNPCHKGALCDTNPLNG----Q 398
C V+S CM P L HL C S G C+ PL G +
Sbjct: 346 ISEEKGPCYRLVSSGRQCMHP-----LSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFK 400
Query: 399 YICTCPQGY 407
IC GY
Sbjct: 401 EICPGGMGY 409
Score = 37.7 bits (86), Expect = 0.14
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 11/77 (14%)
Query: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR-PCLNGGTCHMLSR 126
C K CQN G T + D +T+ + PC+NGG C SR
Sbjct: 39 CTKGSCQNS------CEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCS--SR 90
Query: 127 DTYECTCQVGFTGKECQ 143
D +C C FTGK CQ
Sbjct: 91 D--KCQCPPNFTGKLCQ 105
Score = 37.4 bits (85), Expect = 0.18
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 7/39 (17%)
Query: 1305 VDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
V +C +PC+NGG C+ C+CPP F+G CQ
Sbjct: 74 VVIC-HLPCMNGGQCSSRDK------CQCPPNFTGKLCQ 105
Score = 36.6 bits (83), Expect = 0.31
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 18/87 (20%)
Query: 133 CQVGFTGKECQWTDACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDVNECDIPGH 191
C+V T CQ + C G+T T ++ N + LT + V C +P
Sbjct: 35 CKVTCTKGSCQ-------NSCEKGNTTTLISENGHAADTLTATNFR-----VVICHLP-- 80
Query: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYC 218
C +GG C + +CQCP FTG+ C
Sbjct: 81 CMNGGQCSSRD---KCQCPPNFTGKLC 104
Score = 35.4 bits (80), Expect = 0.70
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 23/103 (22%)
Query: 814 ISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKE-------SPNFESYTCLCAPGWQ 866
+S +T + +T C+ C+ C+N+ C++ S N + L A ++
Sbjct: 19 VSNHTGRIKVVFTPSICKVT---CTKGSCQNS--CEKGNTTTLISENGHAADTLTATNFR 73
Query: 867 GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE 909
C + PCMN G C + C+CPP F+G C+
Sbjct: 74 VVICHL--------PCMNGGQCSSRD---KCQCPPNFTGKLCQ 105
Score = 34.3 bits (77), Expect = 1.6
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 3/29 (10%)
Query: 1195 PCQNGGTCIDLVNHFKCSCPPGTRGLLCE 1223
PC NGG C + KC CPP G LC+
Sbjct: 80 PCMNGGQCS---SRDKCQCPPNFTGKLCQ 105
Score = 34.3 bits (77), Expect = 1.6
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 4/47 (8%)
Query: 443 ECLKGYAGPR---CEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF 486
ECL GY C+ DINEC + CL+ +G + C C GF
Sbjct: 285 ECLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 33.5 bits (75), Expect = 2.7
Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 3/29 (10%)
Query: 540 PCLNGAKCIDHPNGYECQCATGFTGVLCE 568
PC+NG +C +CQC FTG LC+
Sbjct: 80 PCMNGGQCSSRD---KCQCPPNFTGKLCQ 105
Score = 33.1 bits (74), Expect = 3.5
Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 1382 PCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTP 1421
PC +GG C + + CQC P F+G C++ S P
Sbjct: 80 PCMNGGQCSSRDK-----CQCPPNFTGKLCQIPVHGASVP 114
Score = 33.1 bits (74), Expect = 3.5
Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 520 CPPGF---TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP 576
C PG+ CQ DI++C +C++ Y C C GF + +C P
Sbjct: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGP---DPTFSSCVP 341
Query: 577 DP 578
DP
Sbjct: 342 DP 343
Score = 32.7 bits (73), Expect = 4.5
Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 19/123 (15%)
Query: 723 ECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDK-NECLSNPCQNGGTCDNLVNGYRC 781
E + + C G GLS + C G VG + +K +C P +G
Sbjct: 236 ETIGSQC--GKALPGLSKQEDCC--GTVGTSWGFNKCQKCPKKPSYHG-------YNQMM 284
Query: 782 TCKKGFKGYN---CQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCS 838
C G+K N CQ +I+EC G C + + Y C C + G + C
Sbjct: 285 ECLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKI---GFGPDPTFSSCV 340
Query: 839 PNP 841
P+P
Sbjct: 341 PDP 343
Score = 32.3 bits (72), Expect = 5.9
Identities = 22/68 (32%), Positives = 27/68 (39%), Gaps = 16/68 (23%)
Query: 203 GSYQCQCPQGFT-------GQYCDSLY-----VPCAPSPCVNGGTCRQTGDFTFECNCLP 250
GS Q C +G T G D+L V PC+NGG C +C C P
Sbjct: 42 GSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRD----KCQCPP 97
Query: 251 GFEGSTCE 258
F G C+
Sbjct: 98 NFTGKLCQ 105
Score = 32.0 bits (71), Expect = 7.8
Identities = 20/63 (31%), Positives = 24/63 (38%), Gaps = 12/63 (19%)
Query: 1071 PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130
PC N G C + +C CP + G C +P G V L QHS A
Sbjct: 80 PCMNGGQC---SSRDKCQCPPNFTGKLCQIP---------VHGASVPKLYQHSQQPGKAL 127
Query: 1131 NTH 1133
TH
Sbjct: 128 GTH 130
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 227 bits (579), Expect = 1e-58
Identities = 184/546 (33%), Positives = 235/546 (43%), Gaps = 102/546 (18%)
Query: 518 CLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPD 577
C+C PG+ GP C +C L G +CID +C C GFTG C + C D
Sbjct: 174 CVCEPGWKGPNCSEP--ECPGNCHLRG-RCIDG----QCICDDGFTGEDCSQLA--CPSD 224
Query: 578 PCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLND-GRCIDLVNGYQCNCQPG 636
G+C +G+ CIC GY GA CS +I PC + G C+D + C C G
Sbjct: 225 CNDQGKCVNGV----CICFEGYAGADCSREICPV---PCSEEHGTCVDGL----CVCHDG 273
Query: 637 TSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGAT 696
+G +C N C +N G C++ CVC GFTG+ C+ + N C
Sbjct: 274 FAGDDC--NKPLCLNNCYNRGRCVEN----ECVCDEGFTGEDCS---ELICPNDCFDRGR 324
Query: 697 CINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEV 756
CING C C EG C C G C G +C+CD G+ G++C
Sbjct: 325 CINGT----CYCEEGFTGEDCGKPT--CPHACHTQGRCEEG----QCVCDEGFAGVDCS- 373
Query: 757 DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISG 816
+ C ++ C N G C V+G RC C GF G +C + N C G C +
Sbjct: 374 -EKRCPAD-CHNRGRC---VDG-RCECDDGFTGADCG---ELKCPNGCSGHGRCVNG--- 421
Query: 817 YTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDE 876
C C YTG++C + P N C + C E C+C G++G C+ D
Sbjct: 422 -QCVCDEGYTGEDCSQLRCP---NDCHSRGRCVEGK------CVCEQGFKGYDCS---DM 468
Query: 877 CISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
C HG C N MC C G++G DC D C N G C+DG C+
Sbjct: 469 SCPNDCHQHGRCVNG----MCVCDDGYTGEDCR---DRQCPRDCSNRGLCVDG----QCV 517
Query: 937 CLPGFTGDKCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTES 994
C GFTG C LS P C G C VN C C GF G C+ C S
Sbjct: 518 CEDGFTGPDCAE-----LSCPNDCHGQGRC---VNGQ-CVCHEGFMGKDCKEQ--RCP-S 565
Query: 995 SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLG 1054
C G CVDG C+C GFTG C + C S C N G CV G RC C G
Sbjct: 566 DCHGQGRCVDG----QCICHEGFTGLDCGQ--HSCPSD-CNNLGQCVSG----RCICNEG 614
Query: 1055 YTGKNC 1060
Y+G++C
Sbjct: 615 YSGEDC 620
Score = 214 bits (545), Expect = 8e-55
Identities = 180/577 (31%), Positives = 252/577 (43%), Gaps = 108/577 (18%)
Query: 302 CLLQP--NACQNGGTCANRNG----GYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID 355
C LQP C+ R G GCVC GW G +CSE +C +C CID
Sbjct: 146 CCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSE--PECP-GNCHLRGRCID 202
Query: 356 RVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTED 415
C+C +G G C AC S+ C+ C +NG +C C +GY GADC+ +
Sbjct: 203 G----QCICDDGFTGEDCS-QLACPSD-CNDQGKC----VNG--VCICFEGYAGADCSRE 250
Query: 416 VDECAMANSNPC-EHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDK 474
+ C + PC E G CV DG C C G+AG C + C ++ C N C++
Sbjct: 251 I--CPV----PCSEEHGTCV--DGL--CVCHDGFAGDDCNKPL--CLNN-CYNRGRCVEN 297
Query: 475 IGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDID 534
C+C GF G C I C N C + G+C++ C C GFTG +
Sbjct: 298 ----ECVCDEGFTGEDCSELI--C-PNDCFDRGRCINGT----CYCEEGFTG-------E 339
Query: 535 DCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCI 594
DC C + +C C GF GV C E C D + G+C DG C
Sbjct: 340 DCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEK--RCPADCHNRGRCVDG----RCE 393
Query: 595 CNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPC 654
C+ G+ GA C + +C + C GRC VNG QC C G +G +C + C ++
Sbjct: 394 CDDGFTGADCGEL--KC-PNGCSGHGRC---VNG-QCVCDEGYTGEDC--SQLRCPNDCH 444
Query: 655 IHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHH 714
G C++G CVC GF G C+ D N C + C+NG+ C+C +G
Sbjct: 445 SRGRCVEG----KCVCEQGFKGYDCS---DMSCPNDCHQHGRCVNGM----CVCDDGYTG 493
Query: 715 PSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDN 774
C + +C + G C G +C+C+ G+ G +C + C N C G C
Sbjct: 494 EDCRDR--QCPRDCSNRGLCVDG----QCVCEDGFTGPDCA--ELSC-PNDCHGQGRC-- 542
Query: 775 LVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVL 834
VNG +C C +GF G +C+ ++ + C QG C D C C +TG +C
Sbjct: 543 -VNG-QCVCHEGFMGKDCK---EQRCPSDCHGQGRCVDG----QCICHEGFTGLDCG--- 590
Query: 835 APCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCT 871
P+ C N C S C+C G+ G+ C+
Sbjct: 591 QHSCPSDCNNLGQC------VSGRCICNEGYSGEDCS 621
Score = 213 bits (541), Expect = 2e-54
Identities = 183/592 (30%), Positives = 237/592 (40%), Gaps = 118/592 (19%)
Query: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGG 77
CC PA D C G T G G C C G+ G C + C N C G
Sbjct: 146 CCLQPATGRL--DTRPFCSGRGNFST--EGCG-CVCEPGWKGPNCSEPE-CPGN-CHLRG 198
Query: 78 TCVAQAMLGKATCRCASGFTGEDC-QYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVG 136
C+ C C GFTGEDC Q + C C+NG C C G
Sbjct: 199 RCI------DGQCICDDGFTGEDCSQLACPSDCNDQGKCVNG-----------VCICFEG 241
Query: 137 FTGKECQWTDACLSHPCANG-STCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHG 195
+ G +C + C PC+ TC C C GF G C N+ +C +
Sbjct: 242 YAGADCS-REIC-PVPCSEEHGTCVDGL----CVCHDGFAGDDC----NKPLCLNNCYNR 291
Query: 196 GTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGS 255
G C+ +C C +GFTG+ C L P+ C + G C C C GF G
Sbjct: 292 GRCVE----NECVCDEGFTGEDCSELI---CPNDCFDRGRC-----INGTCYCEEGFTGE 339
Query: 256 TCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC 315
C + CP H C G C +G C C + G C+E C P C N G C
Sbjct: 340 DCGK--PTCP-HACHTQGRCEEG----QCVCDEGFAGVDCSEK--RC---PADCHNRGRC 387
Query: 316 ANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHL 375
+ C C +G++G DC E C G + R + C+C EG G C
Sbjct: 388 VDGR----CECDDGFTGADCGE-------LKCPNGCSGHGRCVNGQCVCDEGYTGEDC-- 434
Query: 376 DDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVN 435
N CH C + G+ C C QG+KG DC++ M+ N C G+CVN
Sbjct: 435 SQLRCPNDCHSRGRC----VEGK--CVCEQGFKGYDCSD------MSCPNDCHQHGRCVN 482
Query: 436 TDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHC-ELE 494
C C GY G C +C D C N C+D C+C GF G C EL
Sbjct: 483 G----MCVCDDGYTGEDCRD--RQCPRD-CSNRGLCVDG----QCVCEDGFTGPDCAELS 531
Query: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGY 554
N C G+CV+ QC+C GF G C+ + + C +C+D
Sbjct: 532 C----PNDCHGQGRCVNG----QCVCHEGFMGKDCK---EQRCPSDCHGQGRCVDG---- 576
Query: 555 ECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSD 606
+C C GFTG+ C ++ +C D + GQC G CICN GY G CS+
Sbjct: 577 QCICHEGFTGLDCGQH--SCPSDCNNLGQCVSG----RCICNEGYSGEDCSE 622
Score = 199 bits (505), Expect = 4e-50
Identities = 173/583 (29%), Positives = 231/583 (39%), Gaps = 130/583 (22%)
Query: 848 CKESPNF--ESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSG 905
C NF E C+C PGW+G C+ EC C G C + Q C C GF+G
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEP--ECPGN-CHLRGRCIDGQ----CICDDGFTG 213
Query: 906 MDCEEDIDDCLANP--CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPC-KNGG 962
DC + LA P C + G C++GV C+C G+ G C E PC + G
Sbjct: 214 EDCSQ-----LACPSDCNDQGKCVNGV----CICFEGYAGADCS---REICPVPCSEEHG 261
Query: 963 TCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC 1022
TC D + C C GF G C + C ++C+N G CV+ C+C GFTG C
Sbjct: 262 TCVDGL----CVCHDGFAGDDCNKPL--CL-NNCYNRGRCVEN----ECVCDEGFTGEDC 310
Query: 1023 LHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKK 1082
I + C + G C++G C C G+TG++C C + C +G C
Sbjct: 311 SELI---CPNDCFDRGRCINGT----CYCEEGFTGEDCGKPT--CPHA-CHTQGRC---- 356
Query: 1083 AESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT 1142
E QC+C G+AG C D C + G C++ C+C G+T
Sbjct: 357 EEGQCVCDEGFAGVDCSEKRCPAD-------------CHNRGRCVDG----RCECDDGFT 399
Query: 1143 GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC 1202
G+ C E +C + HG + +C C GY G +C C N C + G C
Sbjct: 400 GADCGEL--KCPNGCSGHGRCVNG-----QCVCDEGYTGEDCSQL--RCPND-CHSRGRC 449
Query: 1203 IDLVNHFKCSCPPGTRGLLCEENI--DDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER 1260
++ KC C G +G C + +DC + C+NG C C G+ GE
Sbjct: 450 VE----GKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNG----------MCVCDDGYTGED 495
Query: 1261 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA 1320
C +C CS+ G L D CVC FTG C CP C G C
Sbjct: 496 CRD--RQC-PRDCSNRG------LCVDGQCVCEDGFTGPDCAEL--SCPN-DCHGQGRCV 543
Query: 1321 VASNMPDGFICRCPPGFSG-----ARCQSSC-GQVKCRKGEQCVHTASGPRCFCPSPRDC 1374
C C GF G RC S C GQ +C G+ H + DC
Sbjct: 544 NGQ-------CVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGF-------TGLDC 589
Query: 1375 ESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAP 1417
S C + G C R C C +SG C + P
Sbjct: 590 GQHSCPSDCNNLGQCVSGR------CICNEGYSGEDCSEVSPP 626
Score = 86.3 bits (212), Expect = 3e-16
Identities = 60/191 (31%), Positives = 80/191 (41%), Gaps = 39/191 (20%)
Query: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
C G CV G C C +G+ GE C+ R C ++ C N G CV C C
Sbjct: 474 CHQHGRCVN-----GMCVCDDGYTGEDCRDRQ-CPRD-CSNRGLCV------DGQCVCED 520
Query: 95 GFTGEDC-QYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPC 153
GFTG DC + S + C C+NG +C C GF GK+C+ C S C
Sbjct: 521 GFTGPDCAELSCPNDCHGQGRCVNG-----------QCVCHEGFMGKDCK-EQRCPSD-C 567
Query: 154 ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF 213
C C C GFTG C + P C + G C+ S +C C +G+
Sbjct: 568 HGQGRCV----DGQCICHEGFTGLDC----GQHSCPSDCNNLGQCV----SGRCICNEGY 615
Query: 214 TGQYCDSLYVP 224
+G+ C + P
Sbjct: 616 SGEDCSEVSPP 626
Score = 50.8 bits (120), Expect = 2e-05
Identities = 49/207 (23%), Positives = 70/207 (33%), Gaps = 39/207 (18%)
Query: 1327 DGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCESGCASSPC 1383
+G C C PG+ G C C +C+ +C C + DC S C
Sbjct: 170 EGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDG----QCICDDGFTGEDCSQLACPSDC 225
Query: 1384 QHGGSCHPQRQPPYYSCQCAPPFSGSRC--ELYTAPPSTPPATCLSQYCADKARDGVCDE 1441
G C C C ++G+ C E+ P S TC+ C DG +
Sbjct: 226 NDQGKCVNG------VCICFEGYAGADCSREICPVPCSEEHGTCVDGLCV--CHDGFAGD 277
Query: 1442 ACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSK 1501
CN C + + +EN C + C EL +C FD C
Sbjct: 278 DCNKPLCLNNCYNRGRCVENECV-CDE-----GFTGEDCSELICPNDC-FDRGRCING-- 328
Query: 1502 TCKYDKYCADHFKDNHCDQGCNSEECG 1528
TC +C++G E+CG
Sbjct: 329 TC-------------YCEEGFTGEDCG 342
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.459
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 122,774,060
Number of Sequences: 37866
Number of extensions: 7216019
Number of successful extensions: 69418
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 540
Number of HSP's successfully gapped in prelim test: 743
Number of HSP's that attempted gapping in prelim test: 19537
Number of HSP's gapped (non-prelim): 14851
length of query: 2471
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2352
effective length of database: 13,741,464
effective search space: 32319923328
effective search space used: 32319923328
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.