Guide to the Human Genome
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Search of human proteins with 239757081

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239757081 PREDICTED: hypothetical protein LOC100127987 [Homo
sapiens]
         (755 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239757081 PREDICTED: hypothetical protein LOC100127987 [Homo ...  1620   0.0  
gi|169212748 PREDICTED: hypothetical protein LOC100127987 [Homo ...  1614   0.0  
gi|169213239 PREDICTED: hypothetical protein LOC100127987 [Homo ...  1613   0.0  
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       73   9e-13
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      66   1e-10
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    65   2e-10
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    65   2e-10
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          61   4e-09
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     59   1e-08
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                58   4e-08
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               58   4e-08
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       57   6e-08
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    57   6e-08
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    57   6e-08
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    57   6e-08
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         57   6e-08
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    55   2e-07
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    55   2e-07
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    55   2e-07
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      54   7e-07
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                54   7e-07
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                    53   9e-07
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    53   9e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    53   9e-07
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     52   2e-06
gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens]      52   2e-06
gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens]       52   2e-06
gi|22027599 alpha 1 type XIII collagen isoform 14 [Homo sapiens]       52   2e-06
gi|22027591 alpha 1 type XIII collagen isoform 10 [Homo sapiens]       52   2e-06
gi|22027577 alpha 1 type XIII collagen isoform 5 [Homo sapiens]        52   2e-06

>gi|239757081 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 1620 bits (4196), Expect = 0.0
 Identities = 755/755 (100%), Positives = 755/755 (100%)

Query: 1   MCSQQAHTFPCSMAMRAWETTITDVRLSWEIRGRGHCVLDRPHSERTVWVHVGGPGCADG 60
           MCSQQAHTFPCSMAMRAWETTITDVRLSWEIRGRGHCVLDRPHSERTVWVHVGGPGCADG
Sbjct: 1   MCSQQAHTFPCSMAMRAWETTITDVRLSWEIRGRGHCVLDRPHSERTVWVHVGGPGCADG 60

Query: 61  KTWSRVATVLGHSARLSWDRNYLVITGAWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGV 120
           KTWSRVATVLGHSARLSWDRNYLVITGAWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGV
Sbjct: 61  KTWSRVATVLGHSARLSWDRNYLVITGAWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGV 120

Query: 121 GCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC 180
           GCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC
Sbjct: 121 GCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC 180

Query: 181 CAHPVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE 240
           CAHPVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE
Sbjct: 181 CAHPVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE 240

Query: 241 PSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGT 300
           PSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGT
Sbjct: 241 PSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGT 300

Query: 301 VPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTH 360
           VPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTH
Sbjct: 301 VPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTH 360

Query: 361 SPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSM 420
           SPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSM
Sbjct: 361 SPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSM 420

Query: 421 CGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSG 480
           CGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSG
Sbjct: 421 CGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSG 480

Query: 481 GSWGETQSPEAGAQGNHVFCVDFAISGGKEDSHRLARSPWPTLGQEIACSLRYVGDIISM 540
           GSWGETQSPEAGAQGNHVFCVDFAISGGKEDSHRLARSPWPTLGQEIACSLRYVGDIISM
Sbjct: 481 GSWGETQSPEAGAQGNHVFCVDFAISGGKEDSHRLARSPWPTLGQEIACSLRYVGDIISM 540

Query: 541 ATETGGNIVFFPLLAVRMWSRDDHTCGIIRENTMARHPRTAGSFPAFKTEMQPSADTQQP 600
           ATETGGNIVFFPLLAVRMWSRDDHTCGIIRENTMARHPRTAGSFPAFKTEMQPSADTQQP
Sbjct: 541 ATETGGNIVFFPLLAVRMWSRDDHTCGIIRENTMARHPRTAGSFPAFKTEMQPSADTQQP 600

Query: 601 TPPGPNHRGKRTANRYTHHPHGGQRALPVHMADAIGHGRADRKGLFPPTQKNALQIATPT 660
           TPPGPNHRGKRTANRYTHHPHGGQRALPVHMADAIGHGRADRKGLFPPTQKNALQIATPT
Sbjct: 601 TPPGPNHRGKRTANRYTHHPHGGQRALPVHMADAIGHGRADRKGLFPPTQKNALQIATPT 660

Query: 661 IPMADSVHFPSTRQMLGLAEGLVMPSEHSRNAMRFPSSAASEQGLELCRPGSGKKGAMAS 720
           IPMADSVHFPSTRQMLGLAEGLVMPSEHSRNAMRFPSSAASEQGLELCRPGSGKKGAMAS
Sbjct: 661 IPMADSVHFPSTRQMLGLAEGLVMPSEHSRNAMRFPSSAASEQGLELCRPGSGKKGAMAS 720

Query: 721 PQPFLVCGVSSPKTPQRPPEGFGHKVPKHPSESSL 755
           PQPFLVCGVSSPKTPQRPPEGFGHKVPKHPSESSL
Sbjct: 721 PQPFLVCGVSSPKTPQRPPEGFGHKVPKHPSESSL 755


>gi|169212748 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 1614 bits (4180), Expect = 0.0
 Identities = 753/755 (99%), Positives = 753/755 (99%)

Query: 1   MCSQQAHTFPCSMAMRAWETTITDVRLSWEIRGRGHCVLDRPHSERTVWVHVGGPGCADG 60
           MCSQQAHTFPCSMAMRAWETTITDVRLSWEIRGRGHCVLDRPHSERTVWVHVGGPGCADG
Sbjct: 1   MCSQQAHTFPCSMAMRAWETTITDVRLSWEIRGRGHCVLDRPHSERTVWVHVGGPGCADG 60

Query: 61  KTWSRVATVLGHSARLSWDRNYLVITGAWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGV 120
           KTWSRVATVLGHSARLSWDRNYLVITGAWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGV
Sbjct: 61  KTWSRVATVLGHSARLSWDRNYLVITGAWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGV 120

Query: 121 GCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC 180
           GCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC
Sbjct: 121 GCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC 180

Query: 181 CAHPVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE 240
           CAHPVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE
Sbjct: 181 CAHPVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE 240

Query: 241 PSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGT 300
           PSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGT
Sbjct: 241 PSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGT 300

Query: 301 VPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTH 360
           VPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTH
Sbjct: 301 VPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTH 360

Query: 361 SPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSM 420
           SPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSM
Sbjct: 361 SPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSM 420

Query: 421 CGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSG 480
           CGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSG
Sbjct: 421 CGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSG 480

Query: 481 GSWGETQSPEAGAQGNHVFCVDFAISGGKEDSHRLARSPWPTLGQEIACSLRYVGDIISM 540
           GSWGETQSPEAGAQGNHVFCVDFAISGGKEDSHRLARSPW TLGQEIACSLRYVGDIISM
Sbjct: 481 GSWGETQSPEAGAQGNHVFCVDFAISGGKEDSHRLARSPWLTLGQEIACSLRYVGDIISM 540

Query: 541 ATETGGNIVFFPLLAVRMWSRDDHTCGIIRENTMARHPRTAGSFPAFKTEMQPSADTQQP 600
           ATETGGNIVFFPLLAVRMWSRDDHTCGIIRENTMARHPRTAGSFPAFKTEMQPSADTQQP
Sbjct: 541 ATETGGNIVFFPLLAVRMWSRDDHTCGIIRENTMARHPRTAGSFPAFKTEMQPSADTQQP 600

Query: 601 TPPGPNHRGKRTANRYTHHPHGGQRALPVHMADAIGHGRADRKGLFPPTQKNALQIATPT 660
           TPPGPNHRGKRTANRYTHHPHGGQRALPVHMADAIGHGRADRKGLFPPTQKNALQIATPT
Sbjct: 601 TPPGPNHRGKRTANRYTHHPHGGQRALPVHMADAIGHGRADRKGLFPPTQKNALQIATPT 660

Query: 661 IPMADSVHFPSTRQMLGLAEGLVMPSEHSRNAMRFPSSAASEQGLELCRPGSGKKGAMAS 720
           IPMADSVHFPSTRQMLGLAEGLVMPSEHSRNAMRFPSSAASEQGLELCRPGSGKKGAMAS
Sbjct: 661 IPMADSVHFPSTRQMLGLAEGLVMPSEHSRNAMRFPSSAASEQGLELCRPGSGKKGAMAS 720

Query: 721 PQPFLVCGVSSPKTPQRPPEGFGHKVPKHPSESSL 755
           PQPFLVCGVSSPKTP RPPEGFGHKVPKHPSESSL
Sbjct: 721 PQPFLVCGVSSPKTPARPPEGFGHKVPKHPSESSL 755


>gi|169213239 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 1613 bits (4177), Expect = 0.0
 Identities = 752/755 (99%), Positives = 753/755 (99%)

Query: 1   MCSQQAHTFPCSMAMRAWETTITDVRLSWEIRGRGHCVLDRPHSERTVWVHVGGPGCADG 60
           MCSQQAHTFPCSMAMRAWETTITDVRLSWEIRGRGHCVLDRPHSERTVWVHVGGPGCADG
Sbjct: 1   MCSQQAHTFPCSMAMRAWETTITDVRLSWEIRGRGHCVLDRPHSERTVWVHVGGPGCADG 60

Query: 61  KTWSRVATVLGHSARLSWDRNYLVITGAWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGV 120
           KTWSRVATVLGHSARLSWDRNYLVITGAWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGV
Sbjct: 61  KTWSRVATVLGHSARLSWDRNYLVITGAWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGV 120

Query: 121 GCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC 180
           GCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC
Sbjct: 121 GCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC 180

Query: 181 CAHPVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE 240
           CAHPVRPAGH+ACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE
Sbjct: 181 CAHPVRPAGHLACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE 240

Query: 241 PSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGT 300
           PSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGT
Sbjct: 241 PSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGT 300

Query: 301 VPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTH 360
           VPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTH
Sbjct: 301 VPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTH 360

Query: 361 SPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSM 420
           SPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSM
Sbjct: 361 SPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSM 420

Query: 421 CGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSG 480
           CGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSG
Sbjct: 421 CGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSG 480

Query: 481 GSWGETQSPEAGAQGNHVFCVDFAISGGKEDSHRLARSPWPTLGQEIACSLRYVGDIISM 540
           GSWGETQSPEAGAQGNHVFCVDFAISGGKEDSHRLARSPW TLGQEIACSLRYVGDIISM
Sbjct: 481 GSWGETQSPEAGAQGNHVFCVDFAISGGKEDSHRLARSPWLTLGQEIACSLRYVGDIISM 540

Query: 541 ATETGGNIVFFPLLAVRMWSRDDHTCGIIRENTMARHPRTAGSFPAFKTEMQPSADTQQP 600
           ATETGGNIVFFPLLAVRMWSRDDHTCGIIRENTMARHPRTAGSFPAFKTEMQPSADTQQP
Sbjct: 541 ATETGGNIVFFPLLAVRMWSRDDHTCGIIRENTMARHPRTAGSFPAFKTEMQPSADTQQP 600

Query: 601 TPPGPNHRGKRTANRYTHHPHGGQRALPVHMADAIGHGRADRKGLFPPTQKNALQIATPT 660
           TPPGPNHRGKRTANRYTHHPHGGQRALPVHMADAIGHGRADRKGLFPPTQKNALQIATPT
Sbjct: 601 TPPGPNHRGKRTANRYTHHPHGGQRALPVHMADAIGHGRADRKGLFPPTQKNALQIATPT 660

Query: 661 IPMADSVHFPSTRQMLGLAEGLVMPSEHSRNAMRFPSSAASEQGLELCRPGSGKKGAMAS 720
           IPMADSVHFPSTRQMLGLAEGLVMPSEHSRNAMRFPSSAASEQGLELCRPGSGKKGAMAS
Sbjct: 661 IPMADSVHFPSTRQMLGLAEGLVMPSEHSRNAMRFPSSAASEQGLELCRPGSGKKGAMAS 720

Query: 721 PQPFLVCGVSSPKTPQRPPEGFGHKVPKHPSESSL 755
           PQPFLVCGVSSPKTP RPPEGFGHKVPKHPSESSL
Sbjct: 721 PQPFLVCGVSSPKTPARPPEGFGHKVPKHPSESSL 755


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 85/303 (28%), Positives = 108/303 (35%), Gaps = 50/303 (16%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPV---RPAGHVACGAGIWT 199
            P G P RP P G  GP    G+   +GPQG   + GL    PV    PAG V        
Sbjct: 1100 PIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGL--QGPVGLPGPAGPVGPPGEDGD 1157

Query: 200  RAQAG-PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPC 257
            + + G P ++      G     G              PTGP+ P  +P        P P 
Sbjct: 1158 KGEIGEPGQKGSKGDKGEQGPPG--------------PTGPQGPIGQPGPSGADGEPGPR 1203

Query: 258  WGAG-HSQTWRQGAGEAQGTRGG-SADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAM 315
               G   Q   +G     G  G     G+P     ++ + G  G +   GPPG       
Sbjct: 1204 GQQGLFGQKGDEGPRGFPGPPGPVGLQGLPG-PPGEKGETGDVGQMGPPGPPGPRGPSGA 1262

Query: 316  PGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH--- 372
            PGA G + P         G  G V  +G PG   E  +PG GG   P   RG        
Sbjct: 1263 PGADGPQGP-----PGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPS 1317

Query: 373  ----------PKGNCSPGSSPG----FGELWPLGQQCPCVAQGPHG----GGKPSQALAA 414
                      P G+  P  SPG     G+  P G+  P    GP G     G+P Q  + 
Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSP 1377

Query: 415  GPT 417
            GPT
Sbjct: 1378 GPT 1380



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 73/278 (26%), Positives = 91/278 (32%), Gaps = 33/278 (11%)

Query: 145  GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG 204
            G P +P P G RGP    G    RGP+G   K G        P G+           + G
Sbjct: 901  GTPGKPGPRGQRGPTGPRGE---RGPRGITGKPG--------PKGNSGGDGPAGPPGERG 949

Query: 205  PH--KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGH 262
            P+  +   G               +P  P  +  TG +  + P        P+   G   
Sbjct: 950  PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTG--- 1006

Query: 263  SQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSK--CGKCGTVPTQGPPGTNPQCAMPGAS 319
             +T   G     G  G   + G+P L   + +K   G  G     GPPG       PG  
Sbjct: 1007 -ETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLR---GFPGDR 1062

Query: 320  GTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSP 379
            G   P+        G  G     GPPG        G  G   PI   G  R  P+G   P
Sbjct: 1063 GLPGPVGA-----LGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG--RPGPQGPPGP 1115

Query: 380  GSSPGF-GELWPLGQQCPCVAQGPHGGGKPSQALAAGP 416
                G  GE  P G       QGP   G P  A   GP
Sbjct: 1116 AGEKGAPGEKGPQGPAGRDGLQGP--VGLPGPAGPVGP 1151



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 75/277 (27%), Positives = 79/277 (28%), Gaps = 45/277 (16%)

Query: 135 LAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPA------ 188
           LA + P  P G   RP P G  G   L G     GPQG     G     P  PA      
Sbjct: 555 LALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQG-----PPGPAGKPGRR 609

Query: 189 GHVACGAGIWTRAQAGPH-KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHA 247
           G            Q GP   R     AG     G         P    P GP        
Sbjct: 610 GRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRG-----DPGPSGPPGPPGDDGERG 664

Query: 248 LSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPP 307
                 PR   G         G     G +G      P        + G  G V  QG P
Sbjct: 665 DDGEVGPRGLPG-------EPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEP 717

Query: 308 GTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG 367
           G   Q   PGA G   P         G  G    +GP G      MPGA G         
Sbjct: 718 GPPGQQGNPGAQGLPGP--------QGAIGPPGEKGPLGKPGLPGMPGADGP-------- 761

Query: 368 RYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG 404
               HP     PG   G G   P G Q P    GP G
Sbjct: 762 --PGHPGKEGPPGEKGGQG---PPGPQGPIGYPGPRG 793



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 73/277 (26%), Positives = 85/277 (30%), Gaps = 39/277 (14%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWR-GPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRA 201
           PPG P  P   GL GP       P+R G  G     G   +     A  +   A +  R 
Sbjct: 500 PPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRG 559

Query: 202 QAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAG 261
            AGP    +G            S  +  +P    P GP     P        P P    G
Sbjct: 560 PAGP----MGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGP--------PGPAGKPG 607

Query: 262 HSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGT 321
                R+G   + G RG      P+         G  G     G PG       PG SG 
Sbjct: 608 -----RRGRAGSDGARGMPGQTGPK---------GDRGFDGLAGLPGEKGHRGDPGPSGP 653

Query: 322 RSPIA-TRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGR-YRSHPKGNCSP 379
             P      R   G+ G     G PG        G  G   P    G   +  PKGN  P
Sbjct: 654 PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGP 713

Query: 380 GSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGP 416
              PG     P GQQ       P   G P    A GP
Sbjct: 714 QGEPG-----PPGQQ-----GNPGAQGLPGPQGAIGP 740



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 91/371 (24%), Positives = 113/371 (30%), Gaps = 63/371 (16%)

Query: 128 QPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRP 187
           +P    LL  + P  PPG P      G  GP+   G     GP G     G         
Sbjct: 677 EPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPG--------- 727

Query: 188 AGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHA 247
                       +   GP     GA     +   L    +P  P +  P G      P  
Sbjct: 728 -----------AQGLPGPQ----GAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGP-- 770

Query: 248 LSTAASPRPCWGAGHSQTWRQGAGEAQGTRG-GSADGIPEL--TCYQRSKCGKCGTVPTQ 304
                   P    G      QG     G RG   ADGI  L  T  ++ + G  G     
Sbjct: 771 --------PGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDM 822

Query: 305 GPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIA 364
           G  G   +   PG  G   P   + R   G  G     GPPG   +  +PG  G      
Sbjct: 823 GIKGDRGEIGPPGPRGEDGPEGPKGRG--GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQG 880

Query: 365 ARGR--YRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG----GGKPSQALAAGPTV 418
            +G   +   P  N   G     G+  P GQ+ P   +G  G     GKP      GP  
Sbjct: 881 PKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKP------GP-- 932

Query: 419 SMCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRR 478
                   +G S    P  PP     G +   G   FP   G           G  GQR 
Sbjct: 933 --------KGNSGGDGPAGPPGE--RGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRG 982

Query: 479 SGGSWGETQSP 489
             G  G+T  P
Sbjct: 983 ETGFQGKTGPP 993



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 65/247 (26%), Positives = 82/247 (33%), Gaps = 29/247 (11%)

Query: 144  PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
            PG P  P P G  GP    G     G  GS   +G     P  P G             A
Sbjct: 1347 PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGE--PGPSGPPGKRG------PPGPA 1398

Query: 204  GPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPS-SRPHALSTAASPRPCWGAGH 262
            GP  R      GA   +GL        P    P GP+ +  +P        P P    G 
Sbjct: 1399 GPEGRQ--GEKGAKGEAGLEGP-----PGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGL 1451

Query: 263  SQTWRQGAGEAQGTRGGSADGIPELT--CYQRSKCGKCGTVPTQGPPGTNPQCA---MPG 317
              +   G     G  G    G+P L      + + G  G +   GPPG   +     +PG
Sbjct: 1452 PGS--PGPDGPPGPMG--PPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1507

Query: 318  ASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNC 377
              G+  P     +   G  G +   GPPG        GA G+  P   +G    HP G  
Sbjct: 1508 PQGSSGPKG--EQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGE-AGHP-GPP 1563

Query: 378  SPGSSPG 384
             P   PG
Sbjct: 1564 GPPGPPG 1570



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 102/419 (24%), Positives = 122/419 (29%), Gaps = 102/419 (24%)

Query: 140  PQKPPG--GPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVR----PAGHVAC 193
            P  PPG  GPQ P+  G  GP    G     GP G     GL      +    PAG    
Sbjct: 992  PPGPPGVVGPQGPT--GETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGK 1049

Query: 194  GAGIWTRAQAGPH--KRAVGA-----------------------AAGAAQSSGLFSKWVP 228
                  R   G       VGA                        AGAA   G     +P
Sbjct: 1050 DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIG-----IP 1104

Query: 229  CQPLSQHPTGPE-------------PSSRPHALSTAASPRPCWGAG----HSQTWRQGAG 271
             +P  Q P GP              P+ R         P P    G           G  
Sbjct: 1105 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEP 1164

Query: 272  EAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIA----- 326
              +G++G   +  P      +   G+ G     G PG   Q  + G  G   P       
Sbjct: 1165 GQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPP 1224

Query: 327  -----------TRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRS-HPK 374
                          + + G  G +   GPPG       PGA G   P    G   +   K
Sbjct: 1225 GPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEK 1284

Query: 375  GNCSPGSSPGF-GELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSL 433
            G       PG  GE  P G   P   +G  G   PS   AAGP                 
Sbjct: 1285 GEPGEAGEPGLPGEGGPPG---PKGERGEKGESGPSG--AAGPPG--------------- 1324

Query: 434  LPKWPPATLWLGDDLFTGS---CHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSP 489
             PK PP     GDD   GS     FP   G          +G  G +   G  G+T SP
Sbjct: 1325 -PKGPP-----GDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSP 1377



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 54/223 (24%), Positives = 68/223 (30%), Gaps = 40/223 (17%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
            P  PPG    P P G  G +   G+    G +G   K+G     P+ P G          
Sbjct: 1385 PSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTG-----PIGPQG---------- 1429

Query: 200  RAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCW 258
             A   P    +    G     GL        P S  P GP  P   P          P  
Sbjct: 1430 -APGKPGPDGLRGIPGPVGEQGL--------PGSPGPDGPPGPMGPPGLPGLKGDSGPKG 1480

Query: 259  GAGH-------SQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNP 311
              GH            QG    +G  G      P+    ++   G  G +   GPPG   
Sbjct: 1481 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPK---GEQGITGPSGPIGPPGPPGLPG 1537

Query: 312  QCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMP 354
                 GA G+  P   +     G+ G     GPPG   E   P
Sbjct: 1538 PPGPKGAKGSSGPTGPK-----GEAGHPGPPGPPGPPGEVIQP 1575



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 77/319 (24%), Positives = 103/319 (32%), Gaps = 65/319 (20%)

Query: 150  PSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPH--- 206
            P P G RGP    G+   +GP G +   G      V   G            + GP    
Sbjct: 1251 PGPPGPRGPSGAPGADGPQGPPGGIGNPGA-----VGEKGEPGEAGEPGLPGEGGPPGPK 1305

Query: 207  -KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGAGHSQ 264
             +R     +G + ++G         P  + P G + P   P  +     P P    G + 
Sbjct: 1306 GERGEKGESGPSGAAG--------PPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPA- 1356

Query: 265  TWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSP 324
                G     G +G   DG P     Q    G  G     GPPG       PG +G    
Sbjct: 1357 ----GQDGPPGDKGD--DGEPG----QTGSPGPTGEPGPSGPPGKR---GPPGPAGPEG- 1402

Query: 325  IATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-------------RYRS 371
                R+ + G  G    +GPPG        GA G   P   RG                 
Sbjct: 1403 ----RQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPD 1458

Query: 372  HPKGNCSPGSSPGF-GELWPLGQQ---------CPCVAQGPHGG-GKPSQALAAGPTVSM 420
             P G   P   PG  G+  P G++          P   QG  G  G P    ++GP    
Sbjct: 1459 GPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPK--- 1515

Query: 421  CGMRPLQGWSRSLLPKWPP 439
             G + + G S  + P  PP
Sbjct: 1516 -GEQGITGPSGPIGPPGPP 1533



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 74/268 (27%), Positives = 88/268 (32%), Gaps = 56/268 (20%)

Query: 262 HSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
           +  T  +G G  +G +G   +  I E         G  G     GPPGT       G  G
Sbjct: 437 NQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPG 496

Query: 321 TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGG---------------------T 359
            R P       + G  G     GPPGT         GG                      
Sbjct: 497 ERGP-----PGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQ 551

Query: 360 HSPIAARG-------RYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG-GGKPSQA 411
            + +A RG         R  P G   PGS    GE   +G Q P   QGP G  GKP + 
Sbjct: 552 QARLALRGPAGPMGLTGRPGPVG--PPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRR 609

Query: 412 LAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQR-CLSPSIQT 470
             AG      G R + G +    PK        GD  F G    P   G R    PS   
Sbjct: 610 GRAGSD----GARGMPGQTG---PK--------GDRGFDGLAGLPGEKGHRGDPGPSGPP 654

Query: 471 N--GGDGQRRSGGSWGETQSP-EAGAQG 495
              G DG+R   G  G    P E G +G
Sbjct: 655 GPPGDDGERGDDGEVGPRGLPGEPGPRG 682



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 43/174 (24%), Positives = 54/174 (31%), Gaps = 27/174 (15%)

Query: 584 FPAFKTEMQPSADTQQPTPPGPNHRGKRTANRYTHHPHGGQRALPVHMADAIGHGRADRK 643
           FP FK +M    D  +  PPGP         +    P+G                  D  
Sbjct: 815 FPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNG------------------DPG 856

Query: 644 GLFPPTQKNALQIATPTIP-------MADSVHFPSTRQMLGLAEGLVMPSEHSRNAMRFP 696
            L PP +K  L +  P +P          S+ FP      G   G   P +      R P
Sbjct: 857 PLGPPGEKGKLGV--PGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGP 914

Query: 697 SSAASEQGLELCRPGSGKKGAMASPQPFLVCGVSSPKTPQRPPEGFGHKVPKHP 750
           +    E+G        G KG      P    G   P  PQ P    G K P  P
Sbjct: 915 TGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGP 968


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 112/412 (27%), Positives = 135/412 (32%), Gaps = 90/412 (21%)

Query: 112 SGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGS-----SP 166
           SGL+   G       A PAG        P+  PG P      G  GPR L G      +P
Sbjct: 271 SGLDGAKG------DAGPAG--------PKGEPGSPGENGAPGQMGPRGLPGERGRPGAP 316

Query: 167 WRGPQGSLCKSGLCCAH----PVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGL 222
             GP G+    G   A     P  PAG       +  + +AGP         G   S G 
Sbjct: 317 --GPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ--------GPRGSEG- 365

Query: 223 FSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSAD 282
                        P G      P   + AA P    GA   Q   +GA  A G  G  A 
Sbjct: 366 -------------PQGVRGEPGPPGPAGAAGPAGNPGAD-GQPGAKGANGAPGIAG--AP 409

Query: 283 GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQ 342
           G P          G  G     GPPG       PGA G++     +     G+ G V  Q
Sbjct: 410 GFPGAR-------GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK-----GEPGPVGVQ 457

Query: 343 GPPGTHAECAMPGAGGTHSPIAARG--RYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQ 400
           GPPG   E    GA G   P    G    R  P     PG+    G   P G++      
Sbjct: 458 GPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPA 517

Query: 401 GPHG----GGKPSQALAAGPTVSMCGMRPLQGWSRSLLP---KWPPATLWLGDDLFTGSC 453
           GP G     G+P +A        + G + L G   S  P     PP     G D   G  
Sbjct: 518 GPKGSPGEAGRPGEA-------GLPGAKGLTGSPGSPGPDGKTGPPGP--AGQDGRPGPP 568

Query: 454 HFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSP----------EAGAQG 495
             P + GQ  +       G  G+    G  G    P          EAGAQG
Sbjct: 569 GPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQG 620



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 79/296 (26%), Positives = 99/296 (33%), Gaps = 39/296 (13%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P+  PG   RP   GL G + L+GS    GP G     G     P    G          
Sbjct: 519 PKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPG-----PAGQDGRPGPPGPPGA 573

Query: 200 RAQAG----PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR 255
           R QAG    P  +      G A   G     VP  P +  P G +  +          P 
Sbjct: 574 RGQAGVMGFPGPKGAAGEPGKAGERG-----VPGPPGAVGPAGKDGEA-----GAQGPPG 623

Query: 256 PCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAM 315
           P   AG  +   QG   + G +G      P     +  + G  G +   GP G   +   
Sbjct: 624 PAGPAG--ERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGF 681

Query: 316 PGASGTRSPIATR-------------RRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSP 362
           PG  G + P                  +   G  G   +QG PG        GA G   P
Sbjct: 682 PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP 741

Query: 363 IAARGRYRSHPKG-NCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPT 417
              RG   + PKG + SPG     G   P+G   P  A G  G   PS    AGPT
Sbjct: 742 KGDRG--DAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSG--PAGPT 793



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 89/346 (25%), Positives = 111/346 (32%), Gaps = 42/346 (12%)

Query: 91  GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQR- 149
           G PG+   +G+T  P   G+D G     G       A   GF       P+   G P + 
Sbjct: 542 GSPGSPGPDGKTGPPGPAGQD-GRPGPPGPPGARGQAGVMGFP-----GPKGAAGEPGKA 595

Query: 150 -----PSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAH-PVRPAGHVACGAGIWTRAQA 203
                P P G  GP    G +  +GP G    +G      P    G            +A
Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655

Query: 204 G-PHKRAVGAAAGAAQSSGLFS-KWVPCQPLSQHPTGPE-------PSSRPHALSTAASP 254
           G P ++ V    GA   SG    +  P +   Q P GP              A   A +P
Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAP 715

Query: 255 RPCWGAG----HSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTN 310
                 G          +GA    G +G   D  P+       K G  G     GPPG  
Sbjct: 716 GAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP- 774

Query: 311 PQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYR 370
                PG  G   P         G  G   A+G PG   E   PG  G   P  A G+  
Sbjct: 775 --AGAPGDKGESGP--------SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQ-- 822

Query: 371 SHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGG-GKPSQALAAG 415
             P     PG +   G+  P G   P    GP G  G P    A G
Sbjct: 823 --PGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARG 866



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 79/303 (26%), Positives = 103/303 (33%), Gaps = 40/303 (13%)

Query: 135 LAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACG 194
           L++ + +K  GG   P P G  GPR L G     GPQG           P    G     
Sbjct: 163 LSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQG--------FQGPPGEPGEPGAS 214

Query: 195 AGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASP 254
             +  R   GP         G     G   K  P +P  + P GP+ +       TA  P
Sbjct: 215 GPMGPRGPPGP--------PGKNGDDGEAGK--PGRPGERGPPGPQGAR--GLPGTAGLP 262

Query: 255 RPCWGAGHS----------QTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQ 304
                 G S              +G   + G  G      P     +R + G  G    +
Sbjct: 263 GMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGAR 322

Query: 305 GPPGTNPQCAMPGASGTRSPI----ATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTH 360
           G  G       PG +G   P     A   + + G  G   ++GP G   E   PG  G  
Sbjct: 323 GNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAA 382

Query: 361 SPIAARGR-YRSHPKG-NCSPG--SSPGF-GELWPLGQQCPCVAQGPHG-GGKPSQALAA 414
            P    G   +   KG N +PG   +PGF G   P G Q P    GP G  G+P    + 
Sbjct: 383 GPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSK 442

Query: 415 GPT 417
           G T
Sbjct: 443 GDT 445



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 107/425 (25%), Positives = 133/425 (31%), Gaps = 62/425 (14%)

Query: 90   AGGPGNWRAEGETEAPLTVGR--DSGLEAGVGVGCGLRTAQPAGFELLAWQHPQK----P 143
            AG PG     G+  AP   G   + G     GV      A P G          K     
Sbjct: 655  AGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGA 714

Query: 144  PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
            PG P      GL+G     G++   GP+G    +G        P G           A  
Sbjct: 715  PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAG--------PKG-----------ADG 755

Query: 204  GPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGAGH 262
             P K  V    G     G      P       P+GP  P+    A      P P   AG 
Sbjct: 756  SPGKDGVRGLTGPIGPPG--PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF 813

Query: 263  S----QTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGA 318
            +       + GA    G  G   D  P          G  G V   G  G       PGA
Sbjct: 814  AGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGA 873

Query: 319  SGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCS 378
            +G             G  G V   GPPG       PG  G       +G     P+G   
Sbjct: 874  TGFP-----------GAAGRV---GPPGPSGNAGPPGPPGPAGKEGGKG-----PRGETG 914

Query: 379  PGSSPGF----GELWPLGQQCPCVAQGPHGG-GKPSQALAAGP--TVSMCGMRPLQGWSR 431
            P   PG     G   P G++    A GP G  G P     AG    V + G R  +G+  
Sbjct: 915  PAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974

Query: 432  SLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSPEA 491
               P   P     G    +G    P   G   L+     +G +G   + GS G   SP  
Sbjct: 975  LPGPSGEPGK--QGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSP-- 1030

Query: 492  GAQGN 496
            GA+G+
Sbjct: 1031 GAKGD 1035



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 72/266 (27%), Positives = 88/266 (33%), Gaps = 45/266 (16%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            PPG    P   G  GP   SG++   GP G   K G                 G   R +
Sbjct: 870  PPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEG-----------------GKGPRGE 912

Query: 203  AGPHKR--AVG--AAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCW 258
             GP  R   VG     G A   G         P +  P G   +  P  +   A  R   
Sbjct: 913  TGPAGRPGEVGPPGPPGPAGEKG--------SPGADGPAGAPGTPGPQGI---AGQRGVV 961

Query: 259  GAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGA 318
            G    Q   +G     G  G      P     +R   G  G     GPPG + +   PGA
Sbjct: 962  GL-PGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGA 1020

Query: 319  SGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCS 378
             G  SP         G  G     GPPG       PGA G   P+   G  +S  +G   
Sbjct: 1021 EG--SPGRDGSPGAKGDRGETGPAGPPGA------PGAPGAPGPVGPAG--KSGDRGETG 1070

Query: 379  PGSSPGFGELWPLGQQCPCVAQGPHG 404
            P      G + P+G + P   QGP G
Sbjct: 1071 PAGPA--GPVGPVGARGPAGPQGPRG 1094



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 102/415 (24%), Positives = 132/415 (31%), Gaps = 46/415 (11%)

Query: 91  GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRP 150
           G PG   A G    P   G+     A    G       P        Q P  PPG     
Sbjct: 374 GPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNS 433

Query: 151 SPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHKRAV 210
              G  G +  +G+    GP G           P  PAG          R + GP     
Sbjct: 434 GEPGAPGSKGDTGAKGEPGPVG--------VQGPPGPAGEEGKRG---ARGEPGP----T 478

Query: 211 GAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGAGHSQTWRQG 269
           G      +  G  S+  P       P GP      P       SP      G +     G
Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEA-----G 533

Query: 270 AGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRR 329
              A+G  G      P+         G+ G     GPPG   Q  + G  G +       
Sbjct: 534 LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKG-----A 588

Query: 330 RSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGF-GEL 388
             + GK G     GPPG        G  G   P    G   +  +G   P  SPGF G  
Sbjct: 589 AGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG--PAGERGEQGPAGSPGFQGLP 646

Query: 389 WPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPP-------AT 441
            P G   P  A  P   G P    A GP+    G R  +G+      + PP       A 
Sbjct: 647 GPAGP--PGEAGKPGEQGVPGDLGAPGPS----GARGERGFPGERGVQGPPGPAGPRGAN 700

Query: 442 LWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWG-ETQSPEAGAQG 495
              G+D   G    P + G +  +P +Q  G  G+R + G  G +    +AG +G
Sbjct: 701 GAPGNDGAKGDAGAPGAPGSQG-APGLQ--GMPGERGAAGLPGPKGDRGDAGPKG 752



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 64/241 (26%), Positives = 83/241 (34%), Gaps = 28/241 (11%)

Query: 145  GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG 204
            G P  P P G  G +  SG+S  RGP G +   GL  A P   +G         +  + G
Sbjct: 971  GFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGL--AGPPGESGREGAPGAEGSPGRDG 1028

Query: 205  PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQ 264
                + GA     ++        P  P +  P GP   S     +  A P    G     
Sbjct: 1029 ----SPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVG----P 1080

Query: 265  TWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSP 324
               +G    QG RG   +   +     R   G  G    QGPPG       PG+ G + P
Sbjct: 1081 VGARGPAGPQGPRGDKGETGEQ---GDRGIKGHRGFSGLQGPPGP------PGSPGEQGP 1131

Query: 325  IATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYRSHPKGNCSPGSSP 383
                     G  G    +GPPG+       G  G   PI   G R R+   G   P   P
Sbjct: 1132 --------SGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPP 1183

Query: 384  G 384
            G
Sbjct: 1184 G 1184



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 80/289 (27%), Positives = 100/289 (34%), Gaps = 58/289 (20%)

Query: 144 PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKS--GLCCAHPVRPAGHVACGAGIWTRA 201
           PG P  P P G  GP  L G+   +   G   KS  G+    P+ P+G          R 
Sbjct: 138 PGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSG---------PRG 188

Query: 202 QAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE----PSSRPHALSTAASPRPC 257
             GP       A G     G      P +P +  P GP     P  +      A  P   
Sbjct: 189 LPGP-----PGAPGPQGFQG--PPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKP--- 238

Query: 258 WGAGHSQTWRQGAGEAQGTRG--GSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAM 315
                 +   +G    QG RG  G+A G+P +  + R   G  G     GP G   +   
Sbjct: 239 -----GRPGERGPPGPQGARGLPGTA-GLPGMKGH-RGFSGLDGAKGDAGPAGPKGEPGS 291

Query: 316 PGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKG 375
           PG +G  +P     R   G+ G   A GP G        GA G              P G
Sbjct: 292 PGENG--APGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAG--------------PPG 335

Query: 376 NCSPGSSPGF----GELWPLGQQCPCVAQGPHG----GGKPSQALAAGP 416
              P   PGF    G     G Q P  ++GP G     G P  A AAGP
Sbjct: 336 PTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGP 384



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 72/290 (24%), Positives = 87/290 (30%), Gaps = 86/290 (29%)

Query: 90   AGGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQR 149
            AG PG    EG   A  + GRD    A    G       PAG           PPG P  
Sbjct: 1006 AGPPGESGREGAPGAEGSPGRDGSPGAKGDRG----ETGPAG-----------PPGAPGA 1050

Query: 150  PSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHKRA 209
            P   G  GP   SG     GP G         A PV P G          R  AGP    
Sbjct: 1051 PGAPGPVGPAGKSGDRGETGPAGP--------AGPVGPVG---------ARGPAGP---- 1089

Query: 210  VGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQG 269
                                    Q P G +                       +T  QG
Sbjct: 1090 ------------------------QGPRGDK----------------------GETGEQG 1103

Query: 270  AGEAQGTRGGS---ADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIA 326
                +G RG S       P  +  ++   G  G    +GPPG+       G +G   PI 
Sbjct: 1104 DRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIG 1163

Query: 327  -TRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKG 375
                R + G  G V   GPPG       P AG   S +    + ++H  G
Sbjct: 1164 PPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGG 1213



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 37/121 (30%), Positives = 43/121 (35%), Gaps = 15/121 (12%)

Query: 300 TVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGT 359
           T   +GP G        G  G R P     R   G  G     GPPG       PG GG 
Sbjct: 107 TTGVEGPKGDT------GPRGPRGPAGPPGRD--GIPGQPGLPGPPGPPGPPGPPGLGGN 158

Query: 360 HSPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG----GGKPSQALAAG 415
            +P  + G       G   PG     G   P G   P  A GP G     G+P +  A+G
Sbjct: 159 FAPQLSYGYDEKSTGGISVPGP---MGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASG 215

Query: 416 P 416
           P
Sbjct: 216 P 216


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 95/360 (26%), Positives = 119/360 (33%), Gaps = 59/360 (16%)

Query: 142 KPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCA-------HPVRPAGHVACG 194
           K P GPQ   P G +GPR   G    +G  G   + G            P  P G    G
Sbjct: 119 KGPPGPQ--GPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLG 176

Query: 195 AGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASP 254
                +   G  ++A GA  G  Q                 P GP     P   + A  P
Sbjct: 177 GNFAAQMAGGFDEKAGGAQLGVMQG----------------PMGPMGPRGPPGPAGAPGP 220

Query: 255 RPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCA 314
           +   G    +    G     G RG      P        + GK G    +GPPG      
Sbjct: 221 QGFQG-NPGEPGEPGVSGPMGPRGPPG---PPGKPGDDGEAGKPGKAGERGPPGPQGARG 276

Query: 315 MPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG----RYR 370
            PG  G   P     R   G  G     G PG   E   PG  G+  P+  RG    R R
Sbjct: 277 FPGTPGL--PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 334

Query: 371 SHPKGNCSPGSSPGFGELWPLGQQCPC-VAQGPHGGGKPSQALAAGPTVSMCGMRPLQGW 429
           + P G  + G+    G+  P G   P   A GP   G P     AGPT +  G    QG 
Sbjct: 335 TGPAG--AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR-GPEGAQG- 390

Query: 430 SRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSP 489
                P+  P T              P S G    S +  T+G  G + S G+ G   +P
Sbjct: 391 -----PRGEPGT--------------PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 431



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 82/285 (28%), Positives = 100/285 (35%), Gaps = 18/285 (6%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P+   G P RP   GL G R L+G     GPQG +  SG       RP      GA    
Sbjct: 541 PKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG-APGEDGRPGPPGPQGARGQP 599

Query: 200 RAQAGPHKRAVGAAAGAAQSSGL-FSKWVPCQPLSQHPTG----PEPSSRPHALSTAASP 254
                P  +      G A   GL  +  +   P     TG    P P+          +P
Sbjct: 600 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 659

Query: 255 RPCWGAG-HSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
            P    G        G G   G +G   + G P L    R + G  G   + G  G    
Sbjct: 660 GPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV-GPRGERGFPGERGSPGAQGLQGP 718

Query: 313 CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY-RS 371
             +PG  GT  P     +   G  G   AQGPPG        GA G   P   RG     
Sbjct: 719 RGLPGTPGTDGP-----KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEK 773

Query: 372 HPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGG-GKPSQALAAG 415
            P+G  +PG   G G   P+G   P  A G  G  G P  A +AG
Sbjct: 774 GPEG--APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 816



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 83/289 (28%), Positives = 96/289 (33%), Gaps = 50/289 (17%)

Query: 145  GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG 204
            G P  P P G  G +   G+S  RGP G +   GL       PAG         +    G
Sbjct: 993  GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGL-----TGPAGEPGREG---SPGADG 1044

Query: 205  PHKR--AVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR-PCWGAG 261
            P  R  A G      ++  + +   P  P S  P GP         + A  P  P   AG
Sbjct: 1045 PPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG 1104

Query: 262  HSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
                  +G    QG RG   + G P     +R   G  G    QG PG        GASG
Sbjct: 1105 -----ARGIQGPQGPRGDKGEAGEPG----ERGLKGHRGFTGLQGLPGPPGPSGDQGASG 1155

Query: 321  TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYRSHPKGNCSP 379
               P   R              GPPG        GA G   PI   G R RS   G   P
Sbjct: 1156 PAGPSGPR--------------GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1201

Query: 380  GSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAA-GPTVSMCGMRPLQ 427
              +PG           P    GP G G    A A  GP     G  PLQ
Sbjct: 1202 PGNPG-----------PPGPPGPPGPGIDMSAFAGLGPREK--GPDPLQ 1237



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 77/290 (26%), Positives = 97/290 (33%), Gaps = 58/290 (20%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P  PPG P  P  GG    +   G     G        G     P+ P G          
Sbjct: 163 PPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG-----PMGPMG---------P 208

Query: 200 RAQAGPHKRAVGAAAGAAQSSGL-FSKWVPCQPLSQHPTGPE----PSSRPHALSTAASP 254
           R   GP        AGA    G   +   P +P    P GP     P  +P     A  P
Sbjct: 209 RGPPGP--------AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP 260

Query: 255 RPCWGAGHSQTWRQGAGEAQGTRG-GSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQC 313
                    +   +G    QG RG     G+P +  + R   G  G     G PG   + 
Sbjct: 261 --------GKAGERGPPGPQGARGFPGTPGLPGVKGH-RGYPGLDGAKGEAGAPGVKGES 311

Query: 314 AMPGASGTRSPIATR----RRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY 369
             PG +G+  P+  R     R + G  G   A+G  G       PG  G   P+   G  
Sbjct: 312 GSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDG------QPGPAGPPGPVGPAG-- 363

Query: 370 RSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG----GGKPSQALAAG 415
                G   PG+    GE  P G + P  AQGP G     G P  A A+G
Sbjct: 364 -----GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASG 408



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 84/319 (26%), Positives = 105/319 (32%), Gaps = 59/319 (18%)

Query: 91  GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRP 150
           G PG    +G    P T G D    A    G       P G      Q P    G P   
Sbjct: 708 GSPGAQGLQGPRGLPGTPGTDGPKGASGPAG-------PPGA-----QGPPGLQGMPGER 755

Query: 151 SPGGLRGPRSLSGSSPWRGPQGSLCK-SGLCCAHPVRPAGHVACGAGIWTRAQAGPHKRA 209
              G+ GP+   G    +GP+G+  K  G     P+ P G          + + GP   A
Sbjct: 756 GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG---EKGEVGPPGPA 812

Query: 210 VGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQG 269
             A A  A             P  +  TGP P     A    A  +P       +  ++G
Sbjct: 813 GSAGARGA-------------PGERGETGP-PGPAGFAGPPGADGQPGAKGEQGEAGQKG 858

Query: 270 AGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRR 329
              A G +G S    P+         G  G    QGPPG       PGA+G         
Sbjct: 859 DAGAPGPQGPSGAPGPQ---GPTGVTGPKGARGAQGPPGAT---GFPGAAG--------- 903

Query: 330 RSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY----RSHPKGNCSPGSSPGF 385
             + G  G+    GPPG       PG  G   P  ARG      R+   G   P   P  
Sbjct: 904 --RVGPPGSNGNPGPPGP------PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP-- 953

Query: 386 GELWPLGQQCPCVAQGPHG 404
           GE    G   P  A+GP G
Sbjct: 954 GEKGEPGDDGPSGAEGPPG 972



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 72/292 (24%), Positives = 93/292 (31%), Gaps = 55/292 (18%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC----------CAHPVRPAG 189
            PQ P G P    P G+ GP+   G+   +GP G+    G               P  P G
Sbjct: 865  PQGPSGAPGPQGPTGVTGPKGARGA---QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921

Query: 190  HVACGAGIWTRAQAGPHKRA----VGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRP 245
                      R  +GP  RA    +   AG     G        +P    P+G E    P
Sbjct: 922  PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG--------EPGDDGPSGAEGPPGP 973

Query: 246  HALS-----------TAASPRPCWGAGHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRS 293
              L+                 P       +  +QGA  A G RG     G P LT     
Sbjct: 974  QGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT----- 1028

Query: 294  KCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAM 353
              G  G    +G PG +      GA+G +       R + G  G   A GPPG+      
Sbjct: 1029 --GPAGEPGREGSPGADGPPGRDGAAGVKGD-----RGETGAVGAPGAPGPPGSPGPAGP 1081

Query: 354  PGAGGTHSPIAARGRYRSHPKGNCSPGSSPGF-GELWPLGQQCPCVAQGPHG 404
             G  G      A+G     P G   P  + G  G   P G +      G  G
Sbjct: 1082 TGKQGDRGEAGAQG-----PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERG 1128



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 97/371 (26%), Positives = 119/371 (32%), Gaps = 53/371 (14%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P+ PPG P +P   G  G    +G     GPQG+    G      V+  GH         
Sbjct: 241 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVK--GHRGYPGLDGA 298

Query: 200 RAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE--PSSRPHALSTAASPRPC 257
           + +AG        A G    SG      P +  S  P GP   P  R         P   
Sbjct: 299 KGEAG--------APGVKGESG-----SPGENGSPGPMGPRGLPGERGR-----TGPAGA 340

Query: 258 WGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPG 317
            GA  +      AG           G P          G+ G    +GP G       PG
Sbjct: 341 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAP----GAKGEAGPTGARGPEGAQGPRGEPG 396

Query: 318 ASGTRSPI-ATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGN 376
             G+  P  A+      G  G   + G PG       PG  G   P  A G     PKG 
Sbjct: 397 TPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL--GPKGQ 454

Query: 377 CSPGSSPGF-GELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLP 435
                  GF GE  P G+  P    GP G   P     AG      G R  +G    + P
Sbjct: 455 TGEPGIAGFKGEQGPKGEPGPA---GPQGAPGP-----AGEE----GKRGARGEPGGVGP 502

Query: 436 KWPPATL-------WLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRS---GGSWGE 485
             PP          + G D   G    P   G   L+     NG  G+       G+ G 
Sbjct: 503 IGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGL 562

Query: 486 TQSP-EAGAQG 495
           T  P +AG QG
Sbjct: 563 TGRPGDAGPQG 573



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 69/264 (26%), Positives = 90/264 (34%), Gaps = 34/264 (12%)

Query: 146 GPQRPS-PGGLRGPRSLSGSSPWRG---PQGSLCKSGLCCAHPVRPAGHVACGAGIWTRA 201
           GP  P+ P G RG +   G S ++G   P G   + G      V   G       +  R 
Sbjct: 642 GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV--PGEAGAPGLVGPRG 699

Query: 202 QAG-PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGA 260
           + G P +R    A G     GL        P +    GP+ +S P     A  P    G 
Sbjct: 700 ERGFPGERGSPGAQGLQGPRGL--------PGTPGTDGPKGASGPAGPPGAQGPPGLQGM 751

Query: 261 GHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
              +    G    +G RG   +  PE    +    G  G +   GP G N      G  G
Sbjct: 752 P-GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN------GEKG 804

Query: 321 TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPG 380
              P         G  G+  A+G PG   E   PG  G   P  A G+    P      G
Sbjct: 805 EVGPP--------GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ----PGAKGEQG 852

Query: 381 SSPGFGELWPLGQQCPCVAQGPHG 404
            +   G+    G Q P  A GP G
Sbjct: 853 EAGQKGDAGAPGPQGPSGAPGPQG 876



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 90/360 (25%), Positives = 111/360 (30%), Gaps = 47/360 (13%)

Query: 138 QHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCA----HPVRPAGHVAC 193
           Q P+  PG P  P P G  G     G     G +GS    G+  A     P  P G    
Sbjct: 389 QGPRGEPGTPGSPGPAGASGNPGTDGIP---GAKGSAGAPGIAGAPGFPGPRGPPGPQGA 445

Query: 194 GAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTG-PEPSSRPHALSTAA 252
              +  + Q G  +  +    G     G        +P    P G P P+          
Sbjct: 446 TGPLGPKGQTG--EPGIAGFKGEQGPKG--------EPGPAGPQGAPGPAGEEGKRGARG 495

Query: 253 SPRPCWGAGHSQTWRQGAGEAQGTRG-GSADGI--PELTCYQRSKCGKCGTVPTQGPPGT 309
            P      G       G   A G RG    DG+  P+    +R   G  G     G PG 
Sbjct: 496 EP-----GGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 550

Query: 310 NPQCAMPGASG-TRSPIATRRRSKCGKCGTVTAQ---GPPGTHAECAMPGAGGTHSPIAA 365
             +  +PGA G T  P     + K G  G        GPPG       PG  G   P  A
Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 610

Query: 366 RGRYRSHPKGNCSPGSSPGFGELWPL-GQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMR 424
            G       G       PG   L  L G+     A GP G   P+            G +
Sbjct: 611 NGE-----PGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ 665

Query: 425 PLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWG 484
            L G      P  PP     G+    G    P   G   L       G  G+R S G+ G
Sbjct: 666 GLPG------PPGPP-----GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQG 714



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 37/125 (29%), Positives = 46/125 (36%), Gaps = 11/125 (8%)

Query: 301 VPTQGPPGTNPQCAMPGASGTRSPIATRR----RSKCGKCGTVTAQGPPGTHAECAMPGA 356
           V  +GPPG        G  G R     +     R + G+ GT    GPPG       PG 
Sbjct: 116 VGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGL 175

Query: 357 GGTHSPIAARGRYRSHPKGNCSPGSSPG-FGELWPLGQQCPCVAQGPHG----GGKPSQA 411
           GG  +   A G       G    G   G  G + P G   P  A GP G     G+P + 
Sbjct: 176 GGNFAAQMAGG--FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEP 233

Query: 412 LAAGP 416
             +GP
Sbjct: 234 GVSGP 238



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 54/233 (23%), Positives = 67/233 (28%), Gaps = 73/233 (31%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            PPG P    P G +G R  +G+    GP G     G+    P  P G          + +
Sbjct: 1072 PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI--QGPQGPRG---------DKGE 1120

Query: 203  AG-PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAG 261
            AG P +R +    G     GL             P  P PS                   
Sbjct: 1121 AGEPGERGLKGHRGFTGLQGL-------------PGPPGPS------------------- 1148

Query: 262  HSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGT 321
                         G +G S               G  G    +GPPG        GA+G 
Sbjct: 1149 -------------GDQGAS---------------GPAGPSGPRGPPGPVGPSGKDGANGI 1180

Query: 322  RSPIA-TRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHP 373
              PI     R + G+ G     G PG       PG G   S  A  G     P
Sbjct: 1181 PGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGP 1233


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 95/360 (26%), Positives = 119/360 (33%), Gaps = 59/360 (16%)

Query: 142 KPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCA-------HPVRPAGHVACG 194
           K P GPQ   P G +GPR   G    +G  G   + G            P  P G    G
Sbjct: 50  KGPPGPQ--GPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLG 107

Query: 195 AGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASP 254
                +   G  ++A GA  G  Q                 P GP     P   + A  P
Sbjct: 108 GNFAAQMAGGFDEKAGGAQLGVMQG----------------PMGPMGPRGPPGPAGAPGP 151

Query: 255 RPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCA 314
           +   G    +    G     G RG      P        + GK G    +GPPG      
Sbjct: 152 QGFQG-NPGEPGEPGVSGPMGPRGPPG---PPGKPGDDGEAGKPGKAGERGPPGPQGARG 207

Query: 315 MPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG----RYR 370
            PG  G   P     R   G  G     G PG   E   PG  G+  P+  RG    R R
Sbjct: 208 FPGTPGL--PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 265

Query: 371 SHPKGNCSPGSSPGFGELWPLGQQCPC-VAQGPHGGGKPSQALAAGPTVSMCGMRPLQGW 429
           + P G  + G+    G+  P G   P   A GP   G P     AGPT +  G    QG 
Sbjct: 266 TGPAG--AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR-GPEGAQG- 321

Query: 430 SRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSP 489
                P+  P T              P S G    S +  T+G  G + S G+ G   +P
Sbjct: 322 -----PRGEPGT--------------PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 362



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 82/285 (28%), Positives = 100/285 (35%), Gaps = 18/285 (6%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P+   G P RP   GL G R L+G     GPQG +  SG       RP      GA    
Sbjct: 472 PKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG-APGEDGRPGPPGPQGARGQP 530

Query: 200 RAQAGPHKRAVGAAAGAAQSSGL-FSKWVPCQPLSQHPTG----PEPSSRPHALSTAASP 254
                P  +      G A   GL  +  +   P     TG    P P+          +P
Sbjct: 531 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 590

Query: 255 RPCWGAG-HSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
            P    G        G G   G +G   + G P L    R + G  G   + G  G    
Sbjct: 591 GPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV-GPRGERGFPGERGSPGAQGLQGP 649

Query: 313 CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY-RS 371
             +PG  GT  P     +   G  G   AQGPPG        GA G   P   RG     
Sbjct: 650 RGLPGTPGTDGP-----KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEK 704

Query: 372 HPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGG-GKPSQALAAG 415
            P+G  +PG   G G   P+G   P  A G  G  G P  A +AG
Sbjct: 705 GPEG--APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 747



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 83/289 (28%), Positives = 96/289 (33%), Gaps = 50/289 (17%)

Query: 145  GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG 204
            G P  P P G  G +   G+S  RGP G +   GL       PAG         +    G
Sbjct: 924  GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGL-----TGPAGEPGREG---SPGADG 975

Query: 205  PHKR--AVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR-PCWGAG 261
            P  R  A G      ++  + +   P  P S  P GP         + A  P  P   AG
Sbjct: 976  PPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG 1035

Query: 262  HSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
                  +G    QG RG   + G P     +R   G  G    QG PG        GASG
Sbjct: 1036 -----ARGIQGPQGPRGDKGEAGEPG----ERGLKGHRGFTGLQGLPGPPGPSGDQGASG 1086

Query: 321  TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYRSHPKGNCSP 379
               P   R              GPPG        GA G   PI   G R RS   G   P
Sbjct: 1087 PAGPSGPR--------------GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1132

Query: 380  GSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAA-GPTVSMCGMRPLQ 427
              +PG           P    GP G G    A A  GP     G  PLQ
Sbjct: 1133 PGNPG-----------PPGPPGPPGPGIDMSAFAGLGPREK--GPDPLQ 1168



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 77/290 (26%), Positives = 97/290 (33%), Gaps = 58/290 (20%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P  PPG P  P  GG    +   G     G        G     P+ P G          
Sbjct: 94  PPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG-----PMGPMG---------P 139

Query: 200 RAQAGPHKRAVGAAAGAAQSSGL-FSKWVPCQPLSQHPTGPE----PSSRPHALSTAASP 254
           R   GP        AGA    G   +   P +P    P GP     P  +P     A  P
Sbjct: 140 RGPPGP--------AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP 191

Query: 255 RPCWGAGHSQTWRQGAGEAQGTRG-GSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQC 313
                    +   +G    QG RG     G+P +  + R   G  G     G PG   + 
Sbjct: 192 --------GKAGERGPPGPQGARGFPGTPGLPGVKGH-RGYPGLDGAKGEAGAPGVKGES 242

Query: 314 AMPGASGTRSPIATR----RRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY 369
             PG +G+  P+  R     R + G  G   A+G  G       PG  G   P+   G  
Sbjct: 243 GSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDG------QPGPAGPPGPVGPAG-- 294

Query: 370 RSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG----GGKPSQALAAG 415
                G   PG+    GE  P G + P  AQGP G     G P  A A+G
Sbjct: 295 -----GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASG 339



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 84/319 (26%), Positives = 105/319 (32%), Gaps = 59/319 (18%)

Query: 91  GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRP 150
           G PG    +G    P T G D    A    G       P G      Q P    G P   
Sbjct: 639 GSPGAQGLQGPRGLPGTPGTDGPKGASGPAG-------PPGA-----QGPPGLQGMPGER 686

Query: 151 SPGGLRGPRSLSGSSPWRGPQGSLCK-SGLCCAHPVRPAGHVACGAGIWTRAQAGPHKRA 209
              G+ GP+   G    +GP+G+  K  G     P+ P G          + + GP   A
Sbjct: 687 GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG---EKGEVGPPGPA 743

Query: 210 VGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQG 269
             A A  A             P  +  TGP P     A    A  +P       +  ++G
Sbjct: 744 GSAGARGA-------------PGERGETGP-PGPAGFAGPPGADGQPGAKGEQGEAGQKG 789

Query: 270 AGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRR 329
              A G +G S    P+         G  G    QGPPG       PGA+G         
Sbjct: 790 DAGAPGPQGPSGAPGPQ---GPTGVTGPKGARGAQGPPGAT---GFPGAAG--------- 834

Query: 330 RSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY----RSHPKGNCSPGSSPGF 385
             + G  G+    GPPG       PG  G   P  ARG      R+   G   P   P  
Sbjct: 835 --RVGPPGSNGNPGPPGP------PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP-- 884

Query: 386 GELWPLGQQCPCVAQGPHG 404
           GE    G   P  A+GP G
Sbjct: 885 GEKGEPGDDGPSGAEGPPG 903



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 72/292 (24%), Positives = 93/292 (31%), Gaps = 55/292 (18%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC----------CAHPVRPAG 189
            PQ P G P    P G+ GP+   G+   +GP G+    G               P  P G
Sbjct: 796  PQGPSGAPGPQGPTGVTGPKGARGA---QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852

Query: 190  HVACGAGIWTRAQAGPHKRA----VGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRP 245
                      R  +GP  RA    +   AG     G        +P    P+G E    P
Sbjct: 853  PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG--------EPGDDGPSGAEGPPGP 904

Query: 246  HALS-----------TAASPRPCWGAGHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRS 293
              L+                 P       +  +QGA  A G RG     G P LT     
Sbjct: 905  QGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT----- 959

Query: 294  KCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAM 353
              G  G    +G PG +      GA+G +       R + G  G   A GPPG+      
Sbjct: 960  --GPAGEPGREGSPGADGPPGRDGAAGVKGD-----RGETGAVGAPGAPGPPGSPGPAGP 1012

Query: 354  PGAGGTHSPIAARGRYRSHPKGNCSPGSSPGF-GELWPLGQQCPCVAQGPHG 404
             G  G      A+G     P G   P  + G  G   P G +      G  G
Sbjct: 1013 TGKQGDRGEAGAQG-----PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERG 1059



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 97/371 (26%), Positives = 119/371 (32%), Gaps = 53/371 (14%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P+ PPG P +P   G  G    +G     GPQG+    G      V+  GH         
Sbjct: 172 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVK--GHRGYPGLDGA 229

Query: 200 RAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE--PSSRPHALSTAASPRPC 257
           + +AG        A G    SG      P +  S  P GP   P  R         P   
Sbjct: 230 KGEAG--------APGVKGESG-----SPGENGSPGPMGPRGLPGERGR-----TGPAGA 271

Query: 258 WGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPG 317
            GA  +      AG           G P          G+ G    +GP G       PG
Sbjct: 272 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAP----GAKGEAGPTGARGPEGAQGPRGEPG 327

Query: 318 ASGTRSPI-ATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGN 376
             G+  P  A+      G  G   + G PG       PG  G   P  A G     PKG 
Sbjct: 328 TPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL--GPKGQ 385

Query: 377 CSPGSSPGF-GELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLP 435
                  GF GE  P G+  P    GP G   P     AG      G R  +G    + P
Sbjct: 386 TGEPGIAGFKGEQGPKGEPGPA---GPQGAPGP-----AGEE----GKRGARGEPGGVGP 433

Query: 436 KWPPATL-------WLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRS---GGSWGE 485
             PP          + G D   G    P   G   L+     NG  G+       G+ G 
Sbjct: 434 IGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGL 493

Query: 486 TQSP-EAGAQG 495
           T  P +AG QG
Sbjct: 494 TGRPGDAGPQG 504



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 69/264 (26%), Positives = 90/264 (34%), Gaps = 34/264 (12%)

Query: 146 GPQRPS-PGGLRGPRSLSGSSPWRG---PQGSLCKSGLCCAHPVRPAGHVACGAGIWTRA 201
           GP  P+ P G RG +   G S ++G   P G   + G      V   G       +  R 
Sbjct: 573 GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV--PGEAGAPGLVGPRG 630

Query: 202 QAG-PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGA 260
           + G P +R    A G     GL        P +    GP+ +S P     A  P    G 
Sbjct: 631 ERGFPGERGSPGAQGLQGPRGL--------PGTPGTDGPKGASGPAGPPGAQGPPGLQGM 682

Query: 261 GHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
              +    G    +G RG   +  PE    +    G  G +   GP G N      G  G
Sbjct: 683 P-GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN------GEKG 735

Query: 321 TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPG 380
              P         G  G+  A+G PG   E   PG  G   P  A G+    P      G
Sbjct: 736 EVGPP--------GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ----PGAKGEQG 783

Query: 381 SSPGFGELWPLGQQCPCVAQGPHG 404
            +   G+    G Q P  A GP G
Sbjct: 784 EAGQKGDAGAPGPQGPSGAPGPQG 807



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 90/360 (25%), Positives = 111/360 (30%), Gaps = 47/360 (13%)

Query: 138 QHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCA----HPVRPAGHVAC 193
           Q P+  PG P  P P G  G     G     G +GS    G+  A     P  P G    
Sbjct: 320 QGPRGEPGTPGSPGPAGASGNPGTDGIP---GAKGSAGAPGIAGAPGFPGPRGPPGPQGA 376

Query: 194 GAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTG-PEPSSRPHALSTAA 252
              +  + Q G  +  +    G     G        +P    P G P P+          
Sbjct: 377 TGPLGPKGQTG--EPGIAGFKGEQGPKG--------EPGPAGPQGAPGPAGEEGKRGARG 426

Query: 253 SPRPCWGAGHSQTWRQGAGEAQGTRG-GSADGI--PELTCYQRSKCGKCGTVPTQGPPGT 309
            P      G       G   A G RG    DG+  P+    +R   G  G     G PG 
Sbjct: 427 EP-----GGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 481

Query: 310 NPQCAMPGASG-TRSPIATRRRSKCGKCGTVTAQ---GPPGTHAECAMPGAGGTHSPIAA 365
             +  +PGA G T  P     + K G  G        GPPG       PG  G   P  A
Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 541

Query: 366 RGRYRSHPKGNCSPGSSPGFGELWPL-GQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMR 424
            G       G       PG   L  L G+     A GP G   P+            G +
Sbjct: 542 NGE-----PGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ 596

Query: 425 PLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWG 484
            L G      P  PP     G+    G    P   G   L       G  G+R S G+ G
Sbjct: 597 GLPG------PPGPP-----GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQG 645



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 37/125 (29%), Positives = 46/125 (36%), Gaps = 11/125 (8%)

Query: 301 VPTQGPPGTNPQCAMPGASGTRSPIATRR----RSKCGKCGTVTAQGPPGTHAECAMPGA 356
           V  +GPPG        G  G R     +     R + G+ GT    GPPG       PG 
Sbjct: 47  VGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGL 106

Query: 357 GGTHSPIAARGRYRSHPKGNCSPGSSPG-FGELWPLGQQCPCVAQGPHG----GGKPSQA 411
           GG  +   A G       G    G   G  G + P G   P  A GP G     G+P + 
Sbjct: 107 GGNFAAQMAGG--FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEP 164

Query: 412 LAAGP 416
             +GP
Sbjct: 165 GVSGP 169



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 54/233 (23%), Positives = 67/233 (28%), Gaps = 73/233 (31%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            PPG P    P G +G R  +G+    GP G     G+    P  P G          + +
Sbjct: 1003 PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI--QGPQGPRG---------DKGE 1051

Query: 203  AG-PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAG 261
            AG P +R +    G     GL             P  P PS                   
Sbjct: 1052 AGEPGERGLKGHRGFTGLQGL-------------PGPPGPS------------------- 1079

Query: 262  HSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGT 321
                         G +G S               G  G    +GPPG        GA+G 
Sbjct: 1080 -------------GDQGAS---------------GPAGPSGPRGPPGPVGPSGKDGANGI 1111

Query: 322  RSPIA-TRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHP 373
              PI     R + G+ G     G PG       PG G   S  A  G     P
Sbjct: 1112 PGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGP 1164


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 98/389 (25%), Positives = 126/389 (32%), Gaps = 54/389 (13%)

Query: 143  PPGGPQRPSPGGLRGPRSLSG-----SSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGI 197
            PPG P    P G +GP  L G       P RG  G     GL    P  P+G V      
Sbjct: 2187 PPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGL--PGPPGPSGLVGPQGSP 2244

Query: 198  WTRAQAGPHKR--AVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR 255
                Q G   +  A G    + +     S  VP  P    P GP+    P      A   
Sbjct: 2245 GLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVG 2304

Query: 256  PCWGAGHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCA 314
                 G        AG+  G  G   D G+P      R + G+ G     G PG + Q  
Sbjct: 2305 LPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPG----PRGEKGEAGRAGEPGDPGEDGQKG 2360

Query: 315  MPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPK 374
             PG  G +           G  G+    GPPG   +  +PG  G    +   G  ++ P+
Sbjct: 2361 APGPKGFKGDPGV------GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPG--QTGPR 2412

Query: 375  GNC-SPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSL 433
            G    PG S   G   P G++           G P      GP  S+             
Sbjct: 2413 GEMGQPGPSGERGLAGPPGRE-----------GIPGPLGPPGPPGSV------------- 2448

Query: 434  LPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSP-EAG 492
                PP    L  D        P   G+R   P I+  G DG+    G  G T  P   G
Sbjct: 2449 ---GPPGASGLKGDKGDPGVGLPGPRGERG-EPGIR--GEDGRPGQEGPRGLTGPPGSRG 2502

Query: 493  AQGNHVFCVDFAISGGKEDSHRLARSPWP 521
             +G         + G K DS  +   P P
Sbjct: 2503 ERGEKGDVGSAGLKGDKGDSAVILGPPGP 2531



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 72/290 (24%), Positives = 90/290 (31%), Gaps = 22/290 (7%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            PPG P  P   G  GP+   GS+  +G +G     G     P R       GA     + 
Sbjct: 1270 PPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGR-PGSPGRAGNPGTPGAPGLKGSP 1328

Query: 203  AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTG-------PEPSSRPHALSTAASPR 255
              P  R      G     G      P Q +     G       P PS  P        P 
Sbjct: 1329 GLPGPRGDPGERGPRGPKG--EPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPG 1386

Query: 256  PCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAM 315
            P    G   T  +G    +G RG    G   +   +    G  G+   QGP G       
Sbjct: 1387 PRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGP------ 1440

Query: 316  PGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYRSHPK 374
            PG  G +           G+ G+   QGP G        G  G   P+   G +    P 
Sbjct: 1441 PGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPP 1500

Query: 375  GNCSPGSSPGF----GELWPLGQQCPCVAQGPHG-GGKPSQALAAGPTVS 419
            G       PG     G   P G   P   QG  G  G+P      GP V+
Sbjct: 1501 GPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVA 1550



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 99/414 (23%), Positives = 136/414 (32%), Gaps = 34/414 (8%)

Query: 91   GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRP 150
            G PG+   +G+   P   G    L   V  G G R     G      + P+ P G P  P
Sbjct: 1685 GSPGSSGPKGDRGEPGPPGPPGRL---VDTGPGAREKGEPGDR--GQEGPRGPKGDPGLP 1739

Query: 151  -SPG-----GLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG 204
             +PG     G RGP    G    RGP G     G     P    G             +G
Sbjct: 1740 GAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRG-----PPGLDGRSGLDGKPGAAGPSG 1794

Query: 205  PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGAGHS 263
            P+      AAG A   G     +P     Q   GP  P   P         +P     + 
Sbjct: 1795 PN-----GAAGKAGDPG--RDGLPGLRGEQGLPGPSGPPGLPG--KPGEDGKPGLNGKNG 1845

Query: 264  QTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRS 323
            +    G    +G +G S     E     + + G  G +  QGPPG       PG      
Sbjct: 1846 EPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGV 1905

Query: 324  PIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSP 383
            P  T  +   G+ G+   QG PG       PG+      +      ++            
Sbjct: 1906 PGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDE 1965

Query: 384  GFGELWPLGQQCPCVAQGPHG-GGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATL 442
              G   P+ ++     +GP G  G+       GP +   G R L+G      P+ PP  L
Sbjct: 1966 SSGSFLPVPER----RRGPKGDSGEQGPPGKEGP-IGFPGERGLKGDRGDPGPQGPPG-L 2019

Query: 443  WLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGET-QSPEAGAQG 495
             LG+    G        G+  +       GG G+    G  GE  +  E G QG
Sbjct: 2020 ALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQG 2073



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 76/296 (25%), Positives = 92/296 (31%), Gaps = 50/296 (16%)

Query: 138  QHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGI 197
            Q P+ PPG        G  GP   +G    RGP G     GL                G+
Sbjct: 1467 QGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGL---------------PGV 1511

Query: 198  WTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPC 257
              R    P  +      G     G   K  P +P      GP  +  P        P   
Sbjct: 1512 AGR----PGAKGPEGPPGPTGRQG--EKGEPGRPGDPAVVGPAVAG-PKGEKGDVGPAGP 1564

Query: 258  WGAGHSQTWRQGAGEA----QGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQC 313
             GA   Q  R   G       G +G   D  P          G+ G     GPPG     
Sbjct: 1565 RGATGVQGERGPPGLVLPGDPGPKGDPGDRGP------IGLTGRAGPPGDSGPPGEKGDP 1618

Query: 314  AMPGASGTRSPIATRRRSKCGKCGTVTAQGP------PGTHAECAMPGAGGTHSPIAARG 367
              PG  G   P     R + G+ G    +GP      PG   E  + GA G   P+  +G
Sbjct: 1619 GRPGPPGPVGP-----RGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKG 1673

Query: 368  RYRSHPKG--NCSPGSS---PGFGELWPLGQQCPCVAQGP--HGGGKPSQALAAGP 416
                  +   N SPGSS      GE  P G     V  GP     G+P      GP
Sbjct: 1674 DQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGP 1729



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 56/197 (28%), Positives = 69/197 (35%), Gaps = 27/197 (13%)

Query: 239  PEPSSRPH-ALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGK 297
            P P   P  AL     P P   AG  +  + G     G  GG  +        +R + G+
Sbjct: 2011 PGPQGPPGLALGERGPPGPSGLAG--EPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGE 2068

Query: 298  CGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAG 357
             G     GPPG      +PG  G   P   +        G    QGPPG       PG+ 
Sbjct: 2069 RGEQGRDGPPG------LPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSN 2122

Query: 358  GTHSPIAARG-------RYRSHPKG-NCSPGSSPGFGELWPLGQ---QCPCVAQGPHGG- 405
            G   P   RG       R    P+G + +PG     G   P G+   Q P    GP GG 
Sbjct: 2123 GDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGH 2182

Query: 406  ------GKPSQALAAGP 416
                  G P  A  AGP
Sbjct: 2183 GDPGPPGAPGLAGPAGP 2199



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 67/254 (26%), Positives = 79/254 (31%), Gaps = 43/254 (16%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAH-------PVRPAGHVACGA 195
            PPG P  P P G  GP+ +S   P  G  G     GL  A           P G      
Sbjct: 2077 PPGLPGTPGPPGPPGPK-VSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPG 2135

Query: 196  GIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR 255
                R + GP         G   + GL        P  +   GPE   +P        P 
Sbjct: 2136 IKGDRGEPGPR--------GQDGNPGL--------PGERGMAGPE--GKPGLQGPRGPPG 2177

Query: 256  PCWGAGHSQTWRQGAGEAQGTRG----GSADGIP-ELTCYQRSKCGKCGTVPTQGPPGTN 310
            P    GH      GA    G  G        G P E     R   G  G V   GPPG +
Sbjct: 2178 PV--GGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPS 2235

Query: 311  PQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYR 370
                  G+ G   P       K G  G   A G  G      +PG+ G   P+       
Sbjct: 2236 GLVGPQGSPGL--PGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVG------ 2287

Query: 371  SHPKGNCSPGSSPG 384
              PKG   P  +PG
Sbjct: 2288 --PKGEPGPTGAPG 2299



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 73/289 (25%), Positives = 86/289 (29%), Gaps = 54/289 (18%)

Query: 141  QKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTR 200
            Q  PG   R    G  GP+   G     GP G L  +G        P            R
Sbjct: 1675 QGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPG----------DR 1724

Query: 201  AQAGPH-KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGP--EPSSRPHALSTAASPRPC 257
             Q GP   +      GA    G+           + P GP  +P  R  A        P 
Sbjct: 1725 GQEGPRGPKGDPGLPGAPGERGIEG--------FRGPPGPQGDPGVRGPAGEKGDRGPPG 1776

Query: 258  WGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPG 317
                     + GA    G  G +               GK G     G PG   +  +PG
Sbjct: 1777 LDGRSGLDGKPGAAGPSGPNGAA---------------GKAGDPGRDGLPGLRGEQGLPG 1821

Query: 318  ASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGN- 376
             SG   P    +  + GK G     G PG   E    G  G        G  R  PKG  
Sbjct: 1822 PSG--PPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREG--RDGPKGER 1877

Query: 377  -----CSPGSSPGF-GELWPLGQQCPCV--AQGPHG-----GGKPSQAL 412
                   P   PG  G + P GQ  P V    GP G     G K  Q L
Sbjct: 1878 GAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGL 1926



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 98/407 (24%), Positives = 126/407 (30%), Gaps = 73/407 (17%)

Query: 91   GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRP 150
            G PG     G    P   G+  G   G G G   R   P          P  PPG     
Sbjct: 1335 GDPGERGPRGPKGEPGAPGQVIG---GEGPGLPGRKGDPG---------PSGPPGPRGPL 1382

Query: 151  SPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHKRAV 210
               G RGP  L G++  +G +G   + G     P  P      G G              
Sbjct: 1383 GDPGPRGPPGLPGTA-MKGDKGDRGERG-----PPGP------GEG-------------- 1416

Query: 211  GAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASP-RPCWGAGHSQTWRQG 269
            G A G     GL     P  P  Q P GP         S   +P  P       +   +G
Sbjct: 1417 GIAPGEPGLPGL-----PGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRG 1471

Query: 270  AGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIA-TR 328
               A G +G      P     ++ + G  G   ++G PG       PGA G   P   T 
Sbjct: 1472 PPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGV---AGRPGAKGPEGPPGPTG 1528

Query: 329  RRSKCGKCGT--------VTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPG 380
            R+ + G+ G             GP G   +    G  G       RG       G+  P 
Sbjct: 1529 RQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPK 1588

Query: 381  SSPG-FGELWPLGQQCPCVAQGPHG-GGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWP 438
              PG  G +   G+  P    GP G  G P +    GP     G R   G       + P
Sbjct: 1589 GDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPV----GPRGRDGEVGEKGDEGP 1644

Query: 439  PATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGE 485
            P           G    P   G+R L  +    G  G++   G  GE
Sbjct: 1645 P-----------GDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGE 1680



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 63/281 (22%), Positives = 85/281 (30%), Gaps = 64/281 (22%)

Query: 144  PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
            PG P  P   G+ G R   G   + GP+G   + G+         G          + +A
Sbjct: 2595 PGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGV--------KGACGLDGEKGDKGEA 2646

Query: 204  GPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHS 263
            GP  R      G A   G   +          P  P  S  P                  
Sbjct: 2647 GPPGR-----PGLAGHKGEMGE----------PGVPGQSGAP------------------ 2673

Query: 264  QTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRS 323
               ++G    +G RG      P+    ++ + G  G     GP G +     PG  G+  
Sbjct: 2674 --GKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVG 2731

Query: 324  PIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSP 383
            P     R   G  G    +GPPG     A PG  G       +GR      G   P    
Sbjct: 2732 P-----RGPEGLQGQKGERGPPGERVVGA-PGVPGAPGERGEQGR-----PGPAGPRGEK 2780

Query: 384  GFGEL----------WPLGQQCPCVAQGPHGGGKPSQALAA 414
            G   L            + Q C C  Q    G +P  + AA
Sbjct: 2781 GEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYAA 2821



 Score = 33.5 bits (75), Expect = 0.75
 Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 20/148 (13%)

Query: 274  QGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKC 333
            +G RG   D  P      R   G  G   ++G PG      +PG  G   P         
Sbjct: 2541 RGPRGLDGDKGP------RGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGP--------Q 2586

Query: 334  GKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG----RYRSHPKGNCS-PGSSPGFGEL 388
            G+ G     G PG+  +  +PG  G    +   G    +     KG C   G     GE 
Sbjct: 2587 GQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEA 2646

Query: 389  WPLGQQCPCVAQGPHG-GGKPSQALAAG 415
             P G+      +G  G  G P Q+ A G
Sbjct: 2647 GPPGRPGLAGHKGEMGEPGVPGQSGAPG 2674



 Score = 33.1 bits (74), Expect = 0.98
 Identities = 37/144 (25%), Positives = 46/144 (31%), Gaps = 22/144 (15%)

Query: 291  QRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPI-------------ATRRRSKCGKCG 337
            Q+ + G+ G     GPPG        GA G + P              A  R    G+ G
Sbjct: 1255 QKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAG 1314

Query: 338  TVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYRSHPKGNCSPGSSPGF-------GELW 389
                 G PG      +PG  G       RG +      G    G  PG        G   
Sbjct: 1315 NPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSG 1374

Query: 390  PLGQQCPCVAQGPHG-GGKPSQAL 412
            P G + P    GP G  G P  A+
Sbjct: 1375 PPGPRGPLGDPGPRGPPGLPGTAM 1398


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 88/329 (26%), Positives = 111/329 (33%), Gaps = 50/329 (15%)

Query: 117 GVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPR------SLSGSSPWRGP 170
           GVG+G G     P G        P+ PPG    P P G +GP         +G +  RGP
Sbjct: 85  GVGLGPG-----PMGL-----MGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGP 134

Query: 171 QGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQ 230
            G   K+G    HP +P      G      A+  P    +    G    +GL        
Sbjct: 135 AGPPGKAGE-DGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGL-------D 186

Query: 231 PLSQHPTGPEPSSRPHALSTAASPRPCWGAG-HSQTWRQGAGEAQGTRG----------- 278
            L   P  P     P A     +P      G   +  R GA    G RG           
Sbjct: 187 GLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPA 246

Query: 279 ---GSA--DGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKC 333
              GSA   G P      + + G  G     GP G   +  +PG SG   P      +  
Sbjct: 247 GPIGSAGPPGFPGAP-GPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGAN-- 303

Query: 334 GKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRS-----HPKGNCSPGSSPGFGEL 388
           G  G   A G PG      +PG  G   P+ A G   +      P    S G S   GE 
Sbjct: 304 GLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEP 363

Query: 389 WPLGQQCPCVAQGPHGGGKPS-QALAAGP 416
              G Q P    G  G   P+ +A +AGP
Sbjct: 364 GSAGPQGPPGPSGEEGKRGPNGEAGSAGP 392



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 77/284 (27%), Positives = 94/284 (33%), Gaps = 52/284 (18%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P  PPG P  P P GL G  + +     +G                        G G   
Sbjct: 58  PTGPPGPPGPPGPPGLGG--NFAAQYDGKG-----------------------VGLGPGP 92

Query: 200 RAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWG 259
               GP  R    AAGA    G        Q  +  P  P  +    A   A  P     
Sbjct: 93  MGLMGP--RGPPGAAGAPGPQGF-------QGPAGEPGEPGQTGPAGARGPAGPPGKAGE 143

Query: 260 AGH----SQTWRQGAGEAQGTRGGSADGIPELTCYQ--RSKCGKCGTVPTQGPPGTNPQC 313
            GH     +   +G    QG RG    G P L  ++  R   G  G     G PG   + 
Sbjct: 144 DGHPGKPGRPGERGVVGPQGARG--FPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEP 201

Query: 314 AMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHP 373
             PG +GT  P  T  R   G+ G V A GP G        G  G   PI + G     P
Sbjct: 202 GAPGENGT--PGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAG-----P 254

Query: 374 KGNCSPGSSPGFGELWPLGQQCPCVAQGPHGG-GKPSQALAAGP 416
            G   PG+    GE+  +G   P    GP G  G P  +   GP
Sbjct: 255 PG--FPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGP 296



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 94/346 (27%), Positives = 118/346 (34%), Gaps = 34/346 (9%)

Query: 85  ITGAW--AGGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQK 142
           +TGA   AG PG   A G    P  +    G     G    +    PAG +  +    + 
Sbjct: 305 LTGAKGAAGLPGVAGAPG-LPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEP 363

Query: 143 PPGGPQRPSPG-----GLRGPRSLSGSSPWRGP---QGSLCKSGLCCAHPVRPAGHVACG 194
              GPQ P PG     G RGP   +GS+   GP   +GS    GL  A      G     
Sbjct: 364 GSAGPQGP-PGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGAD-----GRAGVM 417

Query: 195 AGIWTRAQAGPHK-RAVGAAAGAAQSSGLFS-KWVPCQPLSQHPTGPE-PSSRPHALSTA 251
               +R  +GP   R     AG     GL   + +P  P +  P G E P   P      
Sbjct: 418 GPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLP---GID 474

Query: 252 ASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNP 311
             P P   AG       G     G +G + D         +   G  G     GP G N 
Sbjct: 475 GRPGPIGPAG--ARGEPGNIGFPGPKGPTGDPGKN---GDKGHAGLAGARGAPGPDGNNG 529

Query: 312 QCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRS 371
               PG  G +       +   G  G     GP G   E   PG  G H      G   +
Sbjct: 530 AQGPPGPQGVQG--GKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGP--A 585

Query: 372 HPKGNCSP-GSSPGFGELWPLGQQCPCVAQGPHGG-GKPSQALAAG 415
            P+G   P G S   G   P+G + P    GP G  G+P    A G
Sbjct: 586 GPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVG 631



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 93/354 (26%), Positives = 112/354 (31%), Gaps = 53/354 (14%)

Query: 91  GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQ-PAGFELLAWQHPQKPPGGPQR 149
           G PG   + G    P   GR     AGV    G R A  PAG         + P G   R
Sbjct: 394 GPPGLRGSPGSRGLPGADGR-----AGVMGPPGSRGASGPAGV--------RGPNGDAGR 440

Query: 150 PSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAH----PVRPAGHVACGAGIWTRAQAG- 204
           P   GL GPR L GS    GP G     GL        P+ PAG       I      G 
Sbjct: 441 PGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGP 500

Query: 205 ---PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-------PSSRPHALSTAASP 254
              P K      AG A + G  +        +Q P GP+           P        P
Sbjct: 501 TGDPGKNGDKGHAGLAGARG--APGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLP 558

Query: 255 RPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCA 314
            P   AG  +  + G     G  G      P     +R   G+ G     GP G+     
Sbjct: 559 GPSGPAG--EVGKPGERGLHGEFGLPGPAGPR---GERGPPGESGAAGPTGPIGSRGPSG 613

Query: 315 MPGASGTRSPIATRRRSKCGKCGTVTAQGP---PGTHAECAMPGAGGTHSPIAARGRY-- 369
            PG  G +           G  GT    GP   PG      +PG  G       RG    
Sbjct: 614 PPGPDGNKG-----EPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGN 668

Query: 370 ------RSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGG-GKPSQALAAGP 416
                 R  P    +PG +   G+    G   P    GP G  G+  +   AGP
Sbjct: 669 PGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGP 722



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 90/349 (25%), Positives = 109/349 (31%), Gaps = 42/349 (12%)

Query: 91   GGPGNWRAEGETEAPLTVGRD--SGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQ 148
            G  GN   +G   AP  VG    +G     G       A PAG      +  +  P GP 
Sbjct: 664  GEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPN 723

Query: 149  ----------RPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIW 198
                      +P   G RG +   G +   GP G +  +G        PAG         
Sbjct: 724  GFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAG--------PAGPNGPPGPAG 775

Query: 199  TRAQAGPHKRA--VGAA--AGAAQSSGLFSKWVPCQPLSQHP-TGPEPSSRP--HALSTA 251
            +R   GP       GAA   G    SG+     P  P  +    GP     P        
Sbjct: 776  SRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVG 835

Query: 252  ASPRPCWGAGHSQTWRQGAGEAQGTRGG----SADGIPELTCYQRSKCGKCGTVPTQGPP 307
            A   P +      +   G     GT G      A GI  L    R + G  G     G P
Sbjct: 836  AVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLP-GSRGERGLPGVAGAVGEP 894

Query: 308  GTNPQCAMPGASG----TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGA---GGTH 360
            G       PGA G      SP       + G+ G     GPPG   +    G     G  
Sbjct: 895  GPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNI 954

Query: 361  SPIAARGRYRSHPKGNCSPGSSPG-FGELWPLGQQCPCVAQGPHGGGKP 408
             P+ A G     P G   P    G  GE  P G   P  A GP G   P
Sbjct: 955  GPVGAAG--APGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGP 1001



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 90/335 (26%), Positives = 101/335 (30%), Gaps = 59/335 (17%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAH----PVRPAGHVACGAGIW 198
            PPG    P   G  GP   SG S   GP G   K GL        PV   G V       
Sbjct: 782  PPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPG 841

Query: 199  TRAQAGPHKRA-VGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPC 257
               + GP   A      G     GL         +   P        P        P P 
Sbjct: 842  FAGEKGPSGEAGTAGPPGTPGPQGLLG----APGILGLPGSRGERGLPGVAGAVGEPGPL 897

Query: 258  WGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPG 317
              AG      +G   A G+ G   +G P        + G+ G     GPPG + Q   PG
Sbjct: 898  GIAG--PPGARGPPGAVGSPG--VNGAP-------GEAGRDGNPGNDGPPGRDGQ---PG 943

Query: 318  ASGTRS-PIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYRSHPKG 375
              G R  P         G  G     GP G H      G  G   P  A G R  S P+G
Sbjct: 944  HKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQG 1003

Query: 376  NCSPGSSPGFGELWPLG----------QQCPCVAQGPHGG-GKPSQALAAGP-------- 416
                   P  GE  P G          Q  P +A G HG  G P     AGP        
Sbjct: 1004 IRGDKGEP--GEKGPRGLPGLKGHNGLQGLPGIA-GHHGDQGAPGSVGPAGPRGPAGPSG 1060

Query: 417  ------------TVSMCGMRPLQGWSRSLLPKWPP 439
                        TV   G+R  QG      P  PP
Sbjct: 1061 PAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPP 1095



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 76/294 (25%), Positives = 94/294 (31%), Gaps = 59/294 (20%)

Query: 90   AGGPGNWRAEGETEAPLTVGRDS--------GLEAGVGVGCGLRTAQPAGFELLAWQHPQ 141
            AG PG    +G   AP  +G           G+   VG    L  A P G         +
Sbjct: 855  AGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPG--------AR 906

Query: 142  KPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRA 201
             PPG    P   G  G     G+    GP G   + G          GH         + 
Sbjct: 907  GPPGAVGSPGVNGAPGEAGRDGNPGNDGPPG---RDG--------QPGH---------KG 946

Query: 202  QAG-PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQH----PTGPEPSSRPHALSTAASPRP 256
            + G P       AAGA    G      P  P  +H     TGP   S P   + A  PR 
Sbjct: 947  ERGYPGNIGPVGAAGAPGPHG------PVGPAGKHGNRGETGP---SGPVGPAGAVGPR- 996

Query: 257  CWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQ--RSKCGKCGTVPTQGPPGTNPQCA 314
              G    Q  R   GE  G +G    G+P L  +   +   G  G    QG PG+     
Sbjct: 997  --GPSGPQGIRGDKGEP-GEKGPR--GLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAG 1051

Query: 315  MPGASGTRSPIATRRRS-KCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG 367
              G +G   P     R+   G  G    +GP G       PG  G   P    G
Sbjct: 1052 PRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 98/380 (25%), Positives = 115/380 (30%), Gaps = 59/380 (15%)

Query: 127 AQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVR 186
           A P GF  +    P   PG    P   GLRG   + G    RGP G              
Sbjct: 114 AGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPG-------------- 159

Query: 187 PAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPH 246
           P G              GP    +    GA        + VP  P  Q   GP+    P 
Sbjct: 160 PPG------------LPGPSGITIPGKPGA--------QGVPGPPGFQGEPGPQGEPGPP 199

Query: 247 ALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSA-------DGIPELTCYQRSKCGKCG 299
                         G      QG         G A       DG+P          G  G
Sbjct: 200 GDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLP----------GAPG 249

Query: 300 TVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGT 359
                GPPG       PGA G + P         G  G    QGP G   E    G  G 
Sbjct: 250 DKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGL 309

Query: 360 HSPIAARGRYRSHPKGNCSPGSSPG-FGELWPLGQQCPCVAQGPHG-GGKPSQALAAGPT 417
             P          PKG+  P   PG  G+    G+      QGP G GG P    +AG  
Sbjct: 310 IGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAG-- 367

Query: 418 VSMCGMRPLQGWSRSLLPKWPPATLWL-GDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQ 476
             + G R   G      P  PP    + GD   +G    P   G+R L  +    G  G 
Sbjct: 368 --LPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGP 425

Query: 477 RRSGGSWGETQSP-EAGAQG 495
           +   G  G    P  AGA G
Sbjct: 426 KGEPGFTGRPGGPGVAGALG 445



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 99/339 (29%), Positives = 113/339 (33%), Gaps = 74/339 (21%)

Query: 90  AGGPGNWRAEGETEAPLTVGRDSGLEAGVGVGC-GLRTAQ----PAGFE-LLAWQHPQKP 143
           AG PG     G    P T G   GL    G G  GL   +    PAG   LL  +     
Sbjct: 286 AGLPGPQGPSGAKGEPGTRG-PPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGE 344

Query: 144 PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
            G P    P GL GP  L GS+   G +G           P  P G    G         
Sbjct: 345 DGEPGEQGPQGLGGPPGLPGSAGLPGRRG-----------PPGPKGEAGPG--------- 384

Query: 204 GPHKRAVGAAAGAAQSSGLFSK-WVPCQ---PLSQHPTGPE-PSSRPHALSTAASPRPCW 258
           GP    V    G    SGL  K  VP +   P +  P GP  P   P        P    
Sbjct: 385 GPP--GVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAG 442

Query: 259 GAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGA 318
             G  Q    G     G RG S  GIP L        G  G +  QG PG   +  +PG 
Sbjct: 443 ALG--QKGDLGLPGQPGLRGPS--GIPGLQ-------GPAGPIGPQGLPGLKGEPGLPGP 491

Query: 319 SGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCS 378
            G           + G+ GT    GPPG      +PG+ G   P    G     P G   
Sbjct: 492 PG---------EGRAGEPGTAGPTGPPG------VPGSPGITGPPGPPG-----PPG--P 529

Query: 379 PGSSPGFGELWPLGQQCPCVAQGPHG-----GGKPSQAL 412
           PG+   F E    G   P    G  G     GGKP   L
Sbjct: 530 PGAPGAFDETGIAGLHLP--NGGVEGAVLGKGGKPQFGL 566



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 79/325 (24%), Positives = 106/325 (32%), Gaps = 54/325 (16%)

Query: 140 PQKPPG--GPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGI 197
           P+ PPG  G   P   GL GP+  SG+   +G  G+    GL     + P G+   G   
Sbjct: 271 PKGPPGVDGVGVPGAAGLPGPQGPSGA---KGEPGTRGPPGL-----IGPTGYGMPGL-- 320

Query: 198 WTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPC 257
                 GP     G    A     L  +  P +       GP+    P  L  +A     
Sbjct: 321 -----PGPK----GDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAG---- 367

Query: 258 WGAGHSQTWRQGAGEAQGTRG-GSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMP 316
                    R+G    +G  G G   G+P +        G  G     G PG   +  +P
Sbjct: 368 ------LPGRRGPPGPKGEAGPGGPPGVPGIR-------GDQGPSGLAGKPGVPGERGLP 414

Query: 317 GASGTRSPIATRRRSK-CGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKG 375
           GA G   P   +      G+ G     G  G   +  +PG  G   P    G     P G
Sbjct: 415 GAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGL--QGPAG 472

Query: 376 NCSPGSSPGF-GELWPLGQQCPCVAQGPHGGGKPSQALAAGPT--VSMCGMRPLQGWSRS 432
              P   PG  GE             GP G G+  +   AGPT    + G   + G    
Sbjct: 473 PIGPQGLPGLKGEPG---------LPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGP 523

Query: 433 LLPKWPPATLWLGDDLFTGSCHFPS 457
             P  PP      D+      H P+
Sbjct: 524 PGPPGPPGAPGAFDETGIAGLHLPN 548


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 86/324 (26%), Positives = 104/324 (32%), Gaps = 38/324 (11%)

Query: 91   GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQH--PQKPPGGPQ 148
            G PG   A+GE          +G +   G+   L    P G +    +    + PPG P 
Sbjct: 1294 GAPGRMGAQGEPGL-------AGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPG 1346

Query: 149  RPSPGGLRGPRSLSGSSPW---RGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGP 205
               P G RG R   G   +    G QG   K G     P  P      G      A+   
Sbjct: 1347 DRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQ-GQPGHPGPRGWPGPKGSKGAEGPK 1405

Query: 206  HKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQT 265
             K+    A G     GL           Q   GP        L   A P    G      
Sbjct: 1406 GKQGKAGAPGRRGVQGL-----------QGLPGPRGVVGRQGLEGIAGPDGLPG------ 1448

Query: 266  WRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPI 325
             R G    QG +G   D  P     +R   G  G    QGPPG   +  +PG  G     
Sbjct: 1449 -RDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKR 1507

Query: 326  ATRRRSKC-GKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPG 384
             T  R+   G  G   ++G PG   E   PG  G   P    G      KG   P   PG
Sbjct: 1508 GTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGF--KGIQGPRGPPG 1565

Query: 385  F----GELWPLGQQCPCVAQGPHG 404
                 G + PLG   P    GP G
Sbjct: 1566 LMGKEGIVGPLGILGPSGLPGPKG 1589



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 93/375 (24%), Positives = 123/375 (32%), Gaps = 75/375 (20%)

Query: 144  PGGPQRPSPGGLRGPRSLSG--SSPW----RGPQGSLCKSGLCCAHPVRPAGHVACGAGI 197
            PG P RP P G +G     G    P     +G +G +   G+    P    GH     G+
Sbjct: 981  PGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGV--PGPKGSMGHPGMPGGM 1038

Query: 198  WTRAQAGPH----KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAA 252
             T  + GP      R      GA    G              P GP+ P+    +     
Sbjct: 1039 GTPGEPGPQGPPGSRGPPGMRGAKGRRG--------------PRGPDGPAGEQGSRGLKG 1084

Query: 253  SPRPCWGAGHSQTWRQGAGEAQGTRGG-SADGIPELTCYQRSKCGKCGTVPTQGPPGTNP 311
             P P       +  R G     G RG   + G P             G     GPPGT  
Sbjct: 1085 PPGP-----QGRPGRPGQQGVAGERGHLGSRGFP-------------GIPGPSGPPGTKG 1126

Query: 312  QCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRS 371
                PG  G + PI        G  G +  +GPPG   E  +PG  G    +   G    
Sbjct: 1127 LPGEPGPQGPQGPI--------GPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLG--TP 1176

Query: 372  HPKGNCSPGSSPGF----GELWPLGQQCPCVAQGPHG--GGKPSQALAA--GP--TVSMC 421
              +G       PG     G + P G +      GP G  G K  + L    GP     + 
Sbjct: 1177 GEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVT 1236

Query: 422  GMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGG 481
            G+R  +G S     K        G     G+  +    G+  +       G  G + S G
Sbjct: 1237 GVRGPEGKSGKQGEK--------GRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRG 1288

Query: 482  SWGETQSP-EAGAQG 495
            S G T +P   GAQG
Sbjct: 1289 SLGPTGAPGRMGAQG 1303



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 68/282 (24%), Positives = 97/282 (34%), Gaps = 51/282 (18%)

Query: 139  HPQKP-----PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAH----PVRPAG 189
            HP  P     PG P    P G RGP  + G+   RGP+G    +G   +     P  P G
Sbjct: 1031 HPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQG 1090

Query: 190  HVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGP-------EPS 242
                        + G H  + G       S    +K +P +P  Q P GP        P 
Sbjct: 1091 RPGRPGQQGVAGERG-HLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPK 1149

Query: 243  SRPHALSTAASP---------RPCWGAGHSQTWRQ----------GAGEAQGTRGGSADG 283
              P A+     P          P    G      Q          G     G +G   D 
Sbjct: 1150 GPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDP 1209

Query: 284  IPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIA-TRRRSKCGKCGTVTAQ 342
             P+    +  + G+ G +   GPPG       PG +G R P   + ++ + G+ G   A+
Sbjct: 1210 GPD---GEHGEKGQEGLMGEDGPPGP------PGVTGVRGPEGKSGKQGEKGRTGAKGAK 1260

Query: 343  GPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPG 384
            G  G   E  +PG  G       +G      +G+  P  +PG
Sbjct: 1261 GYQGQLGEMGVPGDPGPPGTPGPKG-----SRGSLGPTGAPG 1297



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 78/272 (28%), Positives = 94/272 (34%), Gaps = 51/272 (18%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P  P G    P P GL G   + G+   RGP G     GL    P  P            
Sbjct: 626 PPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGL----PGPPG----------A 671

Query: 200 RAQAGPHKRAVGAA-AGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCW 258
           + Q G    + G A  GA    GL         LS +P GP P  + H       P P  
Sbjct: 672 KGQKGDPGLSPGKAHDGAKGDMGL-------PGLSGNP-GP-PGRKGH----KGYPGP-- 716

Query: 259 GAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGA 318
            AGH     QG    +G+ G  A G P        + G  G V   GP G+     +PG 
Sbjct: 717 -AGH--PGEQGQPGPEGSPG--AKGYP-------GRQGLPGPVGDPGPKGSRGYIGLPGL 764

Query: 319 SGTRSPIATRRRSKC-GKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNC 377
            G       R      GK G +   G PG   E   PG  G    +   G     P G  
Sbjct: 765 FGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPG-----PPG-- 817

Query: 378 SPGSSPGFGELWPLGQQCPCVAQGPHGG-GKP 408
            PG     G L P+G   P   +G  G  G+P
Sbjct: 818 VPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEP 849



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 93/414 (22%), Positives = 131/414 (31%), Gaps = 74/414 (17%)

Query: 100 GETEAPLTVGRDSGLEA-----GVGVGCGLRTAQPAGFE----LLAWQHPQKPPGGPQRP 150
           G  + PL   + S   A        VG   RT +PA  +    + A + P+  P  P  P
Sbjct: 316 GPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAP 375

Query: 151 SPG--GLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHKR 208
           S     ++ P     ++P      S  KS L                   T+ Q  P  R
Sbjct: 376 STSIVPIKSPHPTQKTAP-----SSFTKSALP------------------TQKQVPPTSR 412

Query: 209 AVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQ 268
            V A               P Q     P  P PS+RP   +T++S +P      ++    
Sbjct: 413 PVPARVSRPAEK-------PIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKIT 465

Query: 269 GAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATR 328
                  +   S    P  T    S     G+  +  PP T     +P  SGT +P    
Sbjct: 466 SHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPAT----MVPPTSGTSTP---- 517

Query: 329 RRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGN------CSPGSS 382
                    T  A   PG+          G+  PI +    ++ PK +        PG +
Sbjct: 518 --------RTAPAVPTPGS-------APTGSKKPIGSEASKKAGPKSSPRKPVPLRPGKA 562

Query: 383 PGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATL 442
                L  L  +       P     P+  LA    +S        G+S   L    P  L
Sbjct: 563 ARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPL 622

Query: 443 WLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSP-EAGAQG 495
            +G     G C  P   G   L P I   G  G R   G +G    P   GA+G
Sbjct: 623 LMGPPGPKGDCGLPGPPGLPGL-PGIP--GARGPRGPPGPYGNPGLPGPPGAKG 673



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 96/381 (25%), Positives = 123/381 (32%), Gaps = 62/381 (16%)

Query: 126 TAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPV 185
           T +P  F  L+   P   PG  +   P     P +   S+P   P  ++   G       
Sbjct: 478 THKPPPFTALS-SSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAP--AVPTPGSAPTGSK 534

Query: 186 RPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRP 245
           +P G  A        +   P     G AA     S L ++  P QP     T P     P
Sbjct: 535 KPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAP 594

Query: 246 HALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQG 305
            A   ++SPRP   +G+S     G+              P L                 G
Sbjct: 595 -AQFLSSSPRPT-SSGYSIFHLAGSTP-----------FPLL----------------MG 625

Query: 306 PPGTNPQCAMPGASGTRS----PIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHS 361
           PPG    C +PG  G       P A   R   G  G     GPPG   +   PG     S
Sbjct: 626 PPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGL----S 681

Query: 362 PIAARGRYRSHPKGNCS-PGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVS- 419
           P    G+     KG+   PG S   G   P G++      GP   G P +    GP  S 
Sbjct: 682 P----GKAHDGAKGDMGLPGLS---GNPGPPGRKGHKGYPGP--AGHPGEQGQPGPEGSP 732

Query: 420 ----MCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDG 475
                 G + L G      PK     + L      G    P S G+R L       G  G
Sbjct: 733 GAKGYPGRQGLPGPVGDPGPKGSRGYIGL-----PGLFGLPGSDGERGLPGVPGKRGKMG 787

Query: 476 QRRSGGSWGETQSPEAGAQGN 496
                G +GE   P  G  GN
Sbjct: 788 MPGFPGVFGERGPP--GLDGN 806



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 33/116 (28%), Positives = 44/116 (37%), Gaps = 13/116 (11%)

Query: 296 GKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPG 355
           G  G    QG  G+      PGA G   P+      K G  G++   GPPG        G
Sbjct: 862 GVSGDPGFQGDKGSQGLPGFPGARGKPGPLG-----KVGDKGSIGFPGPPGPEGFPGDIG 916

Query: 356 AGGTHSPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG-GGKPSQ 410
             G + P   +G+    P     PG     G+L P G + P    G  G  G+P +
Sbjct: 917 PPGDNGPEGMKGK----PGARGLPGPR---GQLGPEGDEGPMGPPGAPGLEGQPGR 965



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 56/203 (27%), Positives = 68/203 (33%), Gaps = 50/203 (24%)

Query: 296  GKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPG 355
            G  G     GP G+     MPG  GT               G    QGPPG+     M G
Sbjct: 1015 GMMGPPGVPGPKGSMGHPGMPGGMGTP--------------GEPGPQGPPGSRGPPGMRG 1060

Query: 356  AGGTHSPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG-GGKPSQALAA 414
            A G           R  P+G   P      GE    G + P    GP G  G+P Q   A
Sbjct: 1061 AKG-----------RRGPRGPDGPA-----GEQGSRGLKGP---PGPQGRPGRPGQQGVA 1101

Query: 415  GPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGD 474
            G      G    +G+     P  PP T  L           P   G +     I   G  
Sbjct: 1102 GER----GHLGSRGFPGIPGPSGPPGTKGL-----------PGEPGPQGPQGPIGPPGEM 1146

Query: 475  GQRRSGGSWGETQSP-EAGAQGN 496
            G +   G+ GE   P EAG +G+
Sbjct: 1147 GPKGPPGAVGEPGLPGEAGMKGD 1169


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 113/402 (28%), Positives = 140/402 (34%), Gaps = 61/402 (15%)

Query: 112 SGLEAGVGVGCG-LRTAQPAGFELLAWQH----PQKPPGGPQRPSPGGLRGPRSLSGSSP 166
           SGL + VG+  G +    P G + L  Q     P  PPG P  P P G  G R   G   
Sbjct: 202 SGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPG 261

Query: 167 WRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKW 226
             G  G   ++G    +P       + GA  +  A   P  +      G     G     
Sbjct: 262 KPGEDGEPGRNG----NPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKG--EVG 315

Query: 227 VPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPE 286
            P       PTGP  +  P        PR   G    +  R G   A G RG  A G+P 
Sbjct: 316 APGSKGEAGPTGPMGAMGP------LGPRGMPG----ERGRLGPQGAPGQRG--AHGMP- 362

Query: 287 LTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPG 346
                    GK G +   G PG++     PG  G   P  T  R   G  G     GPPG
Sbjct: 363 ---------GKPGPMGPLGIPGSSGFPGNPGMKGEAGP--TGARGPEGPQGQRGETGPPG 411

Query: 347 THAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG-- 404
                 +PGA GT     A+G     P G  SPG+S   G   P G   P  + GP G  
Sbjct: 412 PVGSPGLPGAIGTDGTPGAKG-----PTG--SPGTSGPPGSAGPPGSPGPQGSTGPQGIR 464

Query: 405 -----GGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATLW-LGDDLFTGSCHFPSS 458
                 G P     AGP     G   +QG      P  PP      G     G+   P  
Sbjct: 465 GQPGDPGVPGFKGEAGPK-GEPGPHGIQG------PIGPPGEEGKRGPRGDPGTVGPPGP 517

Query: 459 FGQRCLSPSIQTNGGDGQRRSGGSWGET----QSPEAGAQGN 496
            G+R    +    G DG     G+ GE      S   G+QG+
Sbjct: 518 VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGD 559



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 90/336 (26%), Positives = 108/336 (32%), Gaps = 44/336 (13%)

Query: 91  GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRP 150
           G PG    EG+   PL    + G     G   G+R  QP    L   +     PG P   
Sbjct: 576 GNPGVQGPEGKL-GPLGAPGEDGRPGPPG-SIGIR-GQPGSMGLPGPKGSSGDPGKPGEA 632

Query: 151 SPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAH----PVRPAGHVACGAGIWTRAQAGPH 206
              G+ G R   G     GP G +   GL        P  P G            Q  P 
Sbjct: 633 GNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGF-----------QGLPG 681

Query: 207 KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGP-----EPSSRPHALSTAASPRPCWGAG 261
                   G     G     VP  P +  P GP      P  R     T          G
Sbjct: 682 PPGPPGEGGKPGDQG-----VPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGG 736

Query: 262 HSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGT 321
           H     +G+    GT G +  G P L    +   G+ G   T GP G        GA GT
Sbjct: 737 HGPDGPKGSPGPSGTPGDT--GPPGL----QGMPGERGIAGTPGPKGDRGGIGEKGAEGT 790

Query: 322 RSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGS 381
                 R     G  G +   GP G   E   PG  G   P  +RG   S  +G   P  
Sbjct: 791 AGNDGAR-----GLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGS--RGENGPTG 843

Query: 382 SPGF-GELWPLGQQCPCVAQGPHGGGKPSQALAAGP 416
           + GF G   P GQ  P V   P   G+   A + GP
Sbjct: 844 AVGFAGPQGPDGQ--PGVKGEPGEPGQKGDAGSPGP 877



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 91/359 (25%), Positives = 120/359 (33%), Gaps = 77/359 (21%)

Query: 144 PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
           PG P  P   G RG + L G     G  GS  ++G        P G +     +  R   
Sbjct: 290 PGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAG--------PTGPMGAMGPLGPRGMP 341

Query: 204 GPHKR-AVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGH 262
           G   R     A G   + G+  K  P  PL    +   P +    +   A P        
Sbjct: 342 GERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNP--GMKGEAGP-------- 391

Query: 263 SQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTR 322
             T  +G    QG RG +                        GPPG      +PGA GT 
Sbjct: 392 --TGARGPEGPQGQRGET------------------------GPPGPVGSPGLPGAIGTD 425

Query: 323 SPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSS 382
                +     G  G+    GPPG+      PG  G+  P   RG+          PG  
Sbjct: 426 GTPGAK-----GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ----------PGDP 470

Query: 383 --PGF-GELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPP 439
             PGF GE  P G+  P   QGP   G P +    GP          +G   ++ P  P 
Sbjct: 471 GVPGFKGEAGPKGEPGPHGIQGPI--GPPGEEGKRGP----------RGDPGTVGPPGPV 518

Query: 440 ATLWL-GDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSPEA-GAQGN 496
                 G+  F GS   P   G +     + ++G  G +   G  GE   P A G  GN
Sbjct: 519 GERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGN 577



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 74/292 (25%), Positives = 98/292 (33%), Gaps = 41/292 (14%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGL--------CCAHPVRPA------ 188
           P G P    P G RGP+   G    RGPQG   + G+           HP  P       
Sbjct: 133 PAGPPGSQGPRGERGPKGRPGP---RGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSR 189

Query: 189 GHVACGAGIWTRAQAGPHKRAVGAAAG----------AAQSSGLFSKWVPCQPLSQHPTG 238
              A  AG+  ++  G     +  + G            Q  G      P +P    P G
Sbjct: 190 PFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMG 249

Query: 239 PEPSSRPHAL--STAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCG 296
           P  S  P            P       +    G+  A+G  G  A G+P L  ++  K G
Sbjct: 250 PIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPG--APGLPGLKGHRGHK-G 306

Query: 297 KCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGA 356
             G     G PG+  +    G  G   P+    R   G+ G +  QG PG      MPG 
Sbjct: 307 LEGPKGEVGAPGSKGEAGPTGPMGAMGPLGP--RGMPGERGRLGPQGAPGQRGAHGMPGK 364

Query: 357 GGTHSPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKP 408
            G   P+         P  +  PG+    GE  P G + P   QG  G   P
Sbjct: 365 PGPMGPLGI-------PGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGP 409



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 96/355 (27%), Positives = 116/355 (32%), Gaps = 52/355 (14%)

Query: 144  PGGPQRPSPGGLRGPRSLSGSSPWRGPQG-SLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            PG P +    G  GP+ L+GS    GP G    K G     P    G       +     
Sbjct: 863  PGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGP 922

Query: 203  AG----------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
            AG          P K       G   S G      P  P    P GP     P       
Sbjct: 923  AGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGP----PGGPGDKGDPGEDGQPG 978

Query: 253  SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPEL--TCYQRSKCGKCGTVPTQ------ 304
               P   AG   T ++G     G RG    G+P L        K G  G    +      
Sbjct: 979  PDGPPGPAG--TTGQRGIVGMPGQRG--ERGMPGLPGPAGTPGKVGPTGATGDKGPPGPV 1034

Query: 305  GPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIA 364
            GPPG+N     PG  G      T  R   G  G    +G PG        GA GT  P+ 
Sbjct: 1035 GPPGSNGPVGEPGPEGPAGNDGTPGRD--GAVGERGDRGDPGPAGLPGSQGAPGTPGPVG 1092

Query: 365  ARG--RYRSHPKGNCSPGSSPG-FGELWPLGQQCPCVAQGPHGG-GKPSQALAAGPTVSM 420
            A G    R  P G+  P   PG  G+    G Q P   +G HG  G   Q    G T   
Sbjct: 1093 APGDAGQRGDP-GSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFT--- 1148

Query: 421  CGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDG 475
             G++ L G         PP     G +   GS   P  FG R     +  +G +G
Sbjct: 1149 -GLQGLPG---------PP-----GPNGEQGSAGIPGPFGPRGPPGPVGPSGKEG 1188



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 66/247 (26%), Positives = 83/247 (33%), Gaps = 29/247 (11%)

Query: 144 PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
           PG    P P G +G R   GSS  +G QG   + G     P  P      G         
Sbjct: 530 PGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPG----EPGLPGARGLTG----NPGVQ 581

Query: 204 GPHKR--AVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAG 261
           GP  +   +GA     +     S  +  QP S    GP+ SS          P     AG
Sbjct: 582 GPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS-----GDPGKPGEAGNAG 636

Query: 262 HSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQ---GPPGTNPQCAMPGA 318
                ++GA    G  G S    P     +R + G  G    Q   GPPG   +   PG 
Sbjct: 637 --VPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGD 694

Query: 319 SGT-RSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNC 377
            G    P A       G+ G    +G PG        G  G H P          PKG+ 
Sbjct: 695 QGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGP--------DGPKGSP 746

Query: 378 SPGSSPG 384
            P  +PG
Sbjct: 747 GPSGTPG 753



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 89/363 (24%), Positives = 112/363 (30%), Gaps = 58/363 (15%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
            P  P G    P P GL GP    G+   RG  G     G   A P  P G          
Sbjct: 808  PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGF--AGPQGPDGQPGVKGEPGE 865

Query: 200  RAQAG----PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSR-PHALSTAASP 254
              Q G    P  + +  + G    +G     VP     +   GP  ++  P +      P
Sbjct: 866  PGQKGDAGSPGPQGLAGSPGPHGPNG-----VPGLKGGRGTQGPPGATGFPGSAGRVGPP 920

Query: 255  RPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCA 314
             P    G +     G    +G  G   D         R   G  G    +G PG + Q  
Sbjct: 921  GPAGAPGPAGP--LGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQ-- 976

Query: 315  MPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPK 374
             PG  G   P  T      G+ G V   G  G      +PG  GT   +   G   +  K
Sbjct: 977  -PGPDGPPGPAGT-----TGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG--ATGDK 1028

Query: 375  GNCSPGSSPGFGELWPLGQQCPCVAQGPHGG-GKPSQALAAGPTVSMCGMRPLQGWSRSL 433
            G   P   PG     P+G+  P   +GP G  G P +  A G                  
Sbjct: 1029 GPPGPVGPPGSN--GPVGEPGP---EGPAGNDGTPGRDGAVGER---------------- 1067

Query: 434  LPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSP-EAG 492
                       GD    G    P S G       +   G  GQR   GS G    P  AG
Sbjct: 1068 -----------GDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAG 1116

Query: 493  AQG 495
             +G
Sbjct: 1117 KRG 1119



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 60/245 (24%), Positives = 73/245 (29%), Gaps = 50/245 (20%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
            P  P G P    P G  GP   +G+    G  G++ + G        PAG         T
Sbjct: 1030 PPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG--DRGDPGPAGLPGSQGAPGT 1087

Query: 200  RAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWG 259
                GP    VGA   A Q            P S+ P GP                    
Sbjct: 1088 ---PGP----VGAPGDAGQRG---------DPGSRGPIGPP------------------- 1112

Query: 260  AGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGAS 319
                +  ++G    QG RG   D        Q+   G  G     GPPG N +    G  
Sbjct: 1113 ---GRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIP 1169

Query: 320  GTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSP 379
            G   P     R   G  G    +G PG       PG  G+       G     P G   P
Sbjct: 1170 GPFGP-----RGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEG-----PPGEPGP 1219

Query: 380  GSSPG 384
               PG
Sbjct: 1220 PGPPG 1224



 Score = 33.5 bits (75), Expect = 0.75
 Identities = 36/137 (26%), Positives = 49/137 (35%), Gaps = 28/137 (20%)

Query: 275 GTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCG 334
           G RG      P  +   R + G  G    +GP G + +  +PG  G              
Sbjct: 126 GIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPG-------------- 171

Query: 335 KCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGF--GELWPLG 392
                 A GPPG  +    PG  G   P +A+        G    GS  G   G + P+G
Sbjct: 172 ------APGPPGHPSH---PGPDGLSRPFSAQMAGLDEKSG---LGSQVGLMPGSVGPVG 219

Query: 393 QQCPCVAQGPHGGGKPS 409
            + P   QG  GG  P+
Sbjct: 220 PRGPQGLQGQQGGAGPT 236


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 100/365 (27%), Positives = 125/365 (34%), Gaps = 48/365 (13%)

Query: 143  PPGGPQRPSPGGLR---GPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAG----HVACGA 195
            PPG P +  P GLR   G R L G++   G +G+   SG     P  PAG      A G+
Sbjct: 885  PPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG-----PPGPAGSPGERGAAGS 939

Query: 196  GIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR 255
            G        P  +    AAG         K VP +     PTG +    P  L   A P 
Sbjct: 940  GGPIGPPGRPGPQGPPGAAG--------EKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP- 990

Query: 256  PCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAM 315
            P            G    +GT+G   +  P          G  G +   G PG       
Sbjct: 991  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP---------GPPGPIGPVGQPGAAGADGE 1041

Query: 316  PGASGTRSPIATR----RRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYR 370
            PGA G +     +     R   G  G +  QG PG   E    G  G   P    G R  
Sbjct: 1042 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP 1101

Query: 371  SHPKGNCSPGSSP-GFGELWPLGQQC-PCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQG 428
            + P G   P   P G G L P G++  P  +  P   G+P      GP     G R  +G
Sbjct: 1102 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPG---VKGPR----GERGEKG 1154

Query: 429  WSRSLLPKWPPATLW-LGDDLFTGS---CHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWG 484
             S       PP      GDD   G+     FP   G          +G  G R   G  G
Sbjct: 1155 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1214

Query: 485  ETQSP 489
            +  SP
Sbjct: 1215 QPGSP 1219



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 95/361 (26%), Positives = 122/361 (33%), Gaps = 81/361 (22%)

Query: 90   AGGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQR 149
            AGGPG    EG +  P   G             G R A  +G        P  PPG P  
Sbjct: 910  AGGPGLKGNEGPSGPPGPAGSP-----------GERGAAGSG-------GPIGPPGRPGP 951

Query: 150  PSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPV---RPAGHVACGAGIWTRAQAG-P 205
              P G  G + + G    +GP G   + G+    PV    PAG          + + G P
Sbjct: 952  QGPPGAAGEKGVPGE---KGPIGPTGRDGV--QGPVGLPGPAGPPGVAGEDGDKGEVGDP 1006

Query: 206  HKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGP-EPSSRPHALSTAASPRPCWGAGHSQ 264
             ++      G     G              P GP  P  +P A      P      GH  
Sbjct: 1007 GQKGTKGNKGEHGPPG--------------PPGPIGPVGQPGAAGADGEPGARGPQGHF- 1051

Query: 265  TWRQGAGEAQGTRGGSA-------DGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPG 317
                GA   +GTRG +         G+P     ++ + G  G +   GPPG        G
Sbjct: 1052 ----GAKGDEGTRGFNGPPGPIGLQGLPG-PSGEKGETGDVGPMGPPGPPGPRGPAGPNG 1106

Query: 318  ASGTRSPIA-------TRRRSKCGKCGTVTAQGPPGT---------HAECAMPGAGGTHS 361
            A G + P            + + G+ G+   QG PG            E   PG  G   
Sbjct: 1107 ADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1166

Query: 362  PIAARGRYRSHPKGNCSPGSSPGF----GELWPLGQQCPCVAQGPHG-GGKPSQALAAGP 416
            P    G     PKGN  P   PG     GE  P GQ     A+G  G  G+P Q  + GP
Sbjct: 1167 PKGPTG--DDGPKGNPGPVGFPGDPGPPGEGGPRGQD---GAKGDRGEDGEPGQPGSPGP 1221

Query: 417  T 417
            T
Sbjct: 1222 T 1222



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 75/280 (26%), Positives = 87/280 (31%), Gaps = 38/280 (13%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
            PQ P G P    P G  G   L G    RG  G   K+G     P  P G V        
Sbjct: 795  PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG-----PPGPPGVVGPQGAAGE 849

Query: 200  RAQAG----------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHAL- 248
                G          P ++ +   AG   + G      P  P    P G         L 
Sbjct: 850  TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG--DPGPPGAPGKDGPAGLRGFPGERGLP 907

Query: 249  STAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPG 308
             TA  P      G S     G   + G RG +  G P          G  G    QGPPG
Sbjct: 908  GTAGGPGLKGNEGPSGP--PGPAGSPGERGAAGSGGP---------IGPPGRPGPQGPPG 956

Query: 309  TNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGR 368
               +  +PG  G   P  T R    G  G     GPPG   E    G  G       +G 
Sbjct: 957  AAGEKGVPGEKGPIGP--TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGN 1014

Query: 369  YRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKP 408
                 KG   P   P  G + P+GQ     A G  G   P
Sbjct: 1015 -----KGEHGPPGPP--GPIGPVGQPGAAGADGEPGARGP 1047



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 75/276 (27%), Positives = 92/276 (33%), Gaps = 46/276 (16%)

Query: 144  PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
            P GP  P   GL GP+  +G    +GP G   K GL         GH      +  + + 
Sbjct: 783  PHGP--PGERGLPGPQGPNGFPGPKGPPGPPGKDGL--------PGHPGQRGEVGFQGKT 832

Query: 204  GPH-KRAVGAAAGAAQSSGLFSKWVPCQPLSQ--HPTGPEPSSRPHALSTAASPRPCWGA 260
            GP     V    GAA  +G         P+ +  HP  P P        TA         
Sbjct: 833  GPPGPPGVVGPQGAAGETG---------PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 883

Query: 261  GHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGAS 319
            G       G     G RG   + G+P          G  G     GPPG        GA+
Sbjct: 884  GPPGA--PGKDGPAGLRGFPGERGLPGTA----GGPGLKGNEGPSGPPGPAGSPGERGAA 937

Query: 320  GTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSP 379
            G+  PI        G  G    QGPPG   E  +PG  G   P    G     P G   P
Sbjct: 938  GSGGPI--------GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDG--VQGPVGLPGP 987

Query: 380  GSSPGF-------GELWPLGQQCPCVAQGPHGGGKP 408
               PG        GE+   GQ+     +G HG   P
Sbjct: 988  AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGP 1023



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 88/332 (26%), Positives = 102/332 (30%), Gaps = 57/332 (17%)

Query: 91  GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFEL----------LAWQHP 140
           G PG     G   AP   G    L    G G G +    A  E           LA + P
Sbjct: 343 GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGP 402

Query: 141 QKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTR 200
             P G   RP P G  G   L G S   GPQG     GL    P   AG          R
Sbjct: 403 PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL--TGPPGKAGRRGRAGADGAR 460

Query: 201 AQAG----PHKRAVGAAAGAAQSSG----LFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
              G       R      G     G      ++ +P  P      G +    P  L   +
Sbjct: 461 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 520

Query: 253 SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
            PR   G         G     G RG   DG P+         G  G++  QG PG   Q
Sbjct: 521 GPRGLLG----PKGPPGIPGPPGVRG--MDG-PQ---------GPKGSLGPQGEPGPPGQ 564

Query: 313 CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH 372
              PG  G   P     +   G  G    QG PG      +PG  G+  P         H
Sbjct: 565 QGTPGTQGLPGP-----QGAIGPHGEKGPQGKPG------LPGMPGSDGP-------PGH 606

Query: 373 PKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG 404
           P     PG+    G   P G Q P    GP G
Sbjct: 607 PGKEGPPGTK---GNQGPSGPQGPLGYPGPRG 635



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 75/279 (26%), Positives = 87/279 (31%), Gaps = 46/279 (16%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            P G P  P P G  GPR   G+   RG  G   + G        P G       +  R  
Sbjct: 1182 PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG-----SPGPTGENGPPGPLGKRGP 1236

Query: 203  AG-PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGA 260
            AG P         GA    G         P    P GP  P+ +P        P      
Sbjct: 1237 AGSPGSEGRQGGKGAKGDPGAIG-----APGKTGPVGPAGPAGKPGPDGLRGLP-----G 1286

Query: 261  GHSQTWRQGAGEAQGTRGG-SADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGAS 319
               Q  R GA    G  G     G+P L        G  G    +G PG       PG  
Sbjct: 1287 SVGQQGRPGATGQAGPPGPVGPPGLPGLR-------GDAGAKGEKGHPGLIGLIGPPGEQ 1339

Query: 320  GTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSP 379
            G +           G  G    QG PG   E  +PGA G   PI   G     P G   P
Sbjct: 1340 GEK-----------GDRGLPGPQGSPGQKGEMGIPGASG---PIGPGG-----PPGLPGP 1380

Query: 380  GSSPGF-GELWPLGQQCPCVAQGPHG-GGKPSQALAAGP 416
                G  G   P G +     QGP G  G P + +   P
Sbjct: 1381 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1419



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 76/304 (25%), Positives = 96/304 (31%), Gaps = 49/304 (16%)

Query: 135  LAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGL--------CCAHPVR 186
            + +Q    PPG P    P G  G     G     GP G   + GL            P  
Sbjct: 826  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 885

Query: 187  PAGHVACG-AGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSR 244
            P      G AG+    +  P +R +   AG     G           ++ P+GP  P+  
Sbjct: 886  PGAPGKDGPAGL----RGFPGERGLPGTAGGPGLKG-----------NEGPSGPPGPAGS 930

Query: 245  PHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQ 304
            P     A S  P    G  +   QG   A G +G   +  P     +    G  G     
Sbjct: 931  PGERGAAGSGGPIGPPG--RPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPA 988

Query: 305  GPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIA 364
            GPPG   +    G  G      T+     G  G     GPPG       PGA G      
Sbjct: 989  GPPGVAGEDGDKGEVGDPGQKGTK-----GNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1043

Query: 365  ARG-------------RYRSHPKGNCS----PGSSPGFGELWPLGQQCPCVAQGPHGGGK 407
            ARG             R  + P G       PG S   GE   +G   P    GP G   
Sbjct: 1044 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAG 1103

Query: 408  PSQA 411
            P+ A
Sbjct: 1104 PNGA 1107



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 76/295 (25%), Positives = 96/295 (32%), Gaps = 61/295 (20%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
           PPG    P P G  G R   G +   G  G+    G     P R       G G      
Sbjct: 326 PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR----FGSGGG-----D 376

Query: 203 AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA--------SP 254
            GP   A  A A A       +   P  P+  +   P P  +P +              P
Sbjct: 377 KGPVVAAQEAQAQAILQQARLALRGPPGPMG-YTGRPGPLGQPGSPGLKGESGDLGPQGP 435

Query: 255 RPCWG--AGHSQTWRQGAGEAQGTRG----------GSADGIPELTCYQRSKCGKCGTVP 302
           R   G      +  R+G   A G RG             DG+P L   ++   G  G   
Sbjct: 436 RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLP-GEKGHRGDTGAQG 494

Query: 303 TQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSP 362
             GPPG + +    G  G R         + G  G +  +GPPG      +PG  G    
Sbjct: 495 LPGPPGEDGERGDDGEIGPRG-----LPGESGPRGLLGPKGPPG------IPGPPGVRGM 543

Query: 363 IAARGRYRSHPKGNCSPGSSPGFGELWPLGQQ---------CPCVAQGPHGGGKP 408
              +G     PKG+  P   PG     P GQQ          P  A GPHG   P
Sbjct: 544 DGPQG-----PKGSLGPQGEPG-----PPGQQGTPGTQGLPGPQGAIGPHGEKGP 588



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 82/319 (25%), Positives = 102/319 (31%), Gaps = 58/319 (18%)

Query: 140 PQKPPGGP-QRPSPG--GLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAG 196
           PQ  PG P Q+ +PG  GL GP+   G    +GPQG     G+  +    P GH      
Sbjct: 555 PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG--PPGHPGKEGP 612

Query: 197 IWTRAQAGP--------------------------HKRAVGAAAGAAQSSGLFSKWVPCQ 230
             T+   GP                          HK   G          +  K    +
Sbjct: 613 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 672

Query: 231 ---PLSQHPTGPE-PSSRPHALSTAASPRPCWGAGH-SQTWRQGAGEAQGTRGGSA-DGI 284
              P S+   GPE P  R         P      G        G    QG +G     G 
Sbjct: 673 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 732

Query: 285 PELTCYQ--RSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQ 342
           P  +  +  R   GK G    +GP G   Q    GA+G           K G  GT    
Sbjct: 733 PGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG-----------KSGAKGTSGGD 781

Query: 343 GPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGF-GELWPLGQQCPCVAQG 401
           GP G   E  +PG  G +     +G     P G       PG  G+   +G Q      G
Sbjct: 782 GPHGPPGERGLPGPQGPNGFPGPKG-----PPGPPGKDGLPGHPGQRGEVGFQGKTGPPG 836

Query: 402 PHGGGKPSQALAAGPTVSM 420
           P G   P    AAG T  M
Sbjct: 837 PPGVVGPQG--AAGETGPM 853


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 100/365 (27%), Positives = 125/365 (34%), Gaps = 48/365 (13%)

Query: 143  PPGGPQRPSPGGLR---GPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAG----HVACGA 195
            PPG P +  P GLR   G R L G++   G +G+   SG     P  PAG      A G+
Sbjct: 864  PPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG-----PPGPAGSPGERGAAGS 918

Query: 196  GIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR 255
            G        P  +    AAG         K VP +     PTG +    P  L   A P 
Sbjct: 919  GGPIGPPGRPGPQGPPGAAG--------EKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP- 969

Query: 256  PCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAM 315
            P            G    +GT+G   +  P          G  G +   G PG       
Sbjct: 970  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP---------GPPGPIGPVGQPGAAGADGE 1020

Query: 316  PGASGTRSPIATR----RRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYR 370
            PGA G +     +     R   G  G +  QG PG   E    G  G   P    G R  
Sbjct: 1021 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP 1080

Query: 371  SHPKGNCSPGSSP-GFGELWPLGQQC-PCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQG 428
            + P G   P   P G G L P G++  P  +  P   G+P      GP     G R  +G
Sbjct: 1081 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPG---VKGPR----GERGEKG 1133

Query: 429  WSRSLLPKWPPATLW-LGDDLFTGS---CHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWG 484
             S       PP      GDD   G+     FP   G          +G  G R   G  G
Sbjct: 1134 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193

Query: 485  ETQSP 489
            +  SP
Sbjct: 1194 QPGSP 1198



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 95/361 (26%), Positives = 122/361 (33%), Gaps = 81/361 (22%)

Query: 90   AGGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQR 149
            AGGPG    EG +  P   G             G R A  +G        P  PPG P  
Sbjct: 889  AGGPGLKGNEGPSGPPGPAGSP-----------GERGAAGSG-------GPIGPPGRPGP 930

Query: 150  PSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPV---RPAGHVACGAGIWTRAQAG-P 205
              P G  G + + G    +GP G   + G+    PV    PAG          + + G P
Sbjct: 931  QGPPGAAGEKGVPGE---KGPIGPTGRDGV--QGPVGLPGPAGPPGVAGEDGDKGEVGDP 985

Query: 206  HKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGP-EPSSRPHALSTAASPRPCWGAGHSQ 264
             ++      G     G              P GP  P  +P A      P      GH  
Sbjct: 986  GQKGTKGNKGEHGPPG--------------PPGPIGPVGQPGAAGADGEPGARGPQGHF- 1030

Query: 265  TWRQGAGEAQGTRGGSA-------DGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPG 317
                GA   +GTRG +         G+P     ++ + G  G +   GPPG        G
Sbjct: 1031 ----GAKGDEGTRGFNGPPGPIGLQGLPG-PSGEKGETGDVGPMGPPGPPGPRGPAGPNG 1085

Query: 318  ASGTRSPIA-------TRRRSKCGKCGTVTAQGPPGT---------HAECAMPGAGGTHS 361
            A G + P            + + G+ G+   QG PG            E   PG  G   
Sbjct: 1086 ADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1145

Query: 362  PIAARGRYRSHPKGNCSPGSSPGF----GELWPLGQQCPCVAQGPHG-GGKPSQALAAGP 416
            P    G     PKGN  P   PG     GE  P GQ     A+G  G  G+P Q  + GP
Sbjct: 1146 PKGPTG--DDGPKGNPGPVGFPGDPGPPGEGGPRGQD---GAKGDRGEDGEPGQPGSPGP 1200

Query: 417  T 417
            T
Sbjct: 1201 T 1201



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 75/280 (26%), Positives = 87/280 (31%), Gaps = 38/280 (13%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
            PQ P G P    P G  G   L G    RG  G   K+G     P  P G V        
Sbjct: 774  PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG-----PPGPPGVVGPQGAAGE 828

Query: 200  RAQAG----------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHAL- 248
                G          P ++ +   AG   + G      P  P    P G         L 
Sbjct: 829  TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG--DPGPPGAPGKDGPAGLRGFPGERGLP 886

Query: 249  STAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPG 308
             TA  P      G S     G   + G RG +  G P          G  G    QGPPG
Sbjct: 887  GTAGGPGLKGNEGPSGP--PGPAGSPGERGAAGSGGP---------IGPPGRPGPQGPPG 935

Query: 309  TNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGR 368
               +  +PG  G   P  T R    G  G     GPPG   E    G  G       +G 
Sbjct: 936  AAGEKGVPGEKGPIGP--TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGN 993

Query: 369  YRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKP 408
                 KG   P   P  G + P+GQ     A G  G   P
Sbjct: 994  -----KGEHGPPGPP--GPIGPVGQPGAAGADGEPGARGP 1026



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 75/276 (27%), Positives = 92/276 (33%), Gaps = 46/276 (16%)

Query: 144  PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
            P GP  P   GL GP+  +G    +GP G   K GL         GH      +  + + 
Sbjct: 762  PHGP--PGERGLPGPQGPNGFPGPKGPPGPPGKDGL--------PGHPGQRGEVGFQGKT 811

Query: 204  GPH-KRAVGAAAGAAQSSGLFSKWVPCQPLSQ--HPTGPEPSSRPHALSTAASPRPCWGA 260
            GP     V    GAA  +G         P+ +  HP  P P        TA         
Sbjct: 812  GPPGPPGVVGPQGAAGETG---------PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 862

Query: 261  GHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGAS 319
            G       G     G RG   + G+P          G  G     GPPG        GA+
Sbjct: 863  GPPGA--PGKDGPAGLRGFPGERGLPGTA----GGPGLKGNEGPSGPPGPAGSPGERGAA 916

Query: 320  GTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSP 379
            G+  PI        G  G    QGPPG   E  +PG  G   P    G     P G   P
Sbjct: 917  GSGGPI--------GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDG--VQGPVGLPGP 966

Query: 380  GSSPGF-------GELWPLGQQCPCVAQGPHGGGKP 408
               PG        GE+   GQ+     +G HG   P
Sbjct: 967  AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGP 1002



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 88/332 (26%), Positives = 102/332 (30%), Gaps = 57/332 (17%)

Query: 91  GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFEL----------LAWQHP 140
           G PG     G   AP   G    L    G G G +    A  E           LA + P
Sbjct: 322 GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGP 381

Query: 141 QKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTR 200
             P G   RP P G  G   L G S   GPQG     GL    P   AG          R
Sbjct: 382 PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL--TGPPGKAGRRGRAGADGAR 439

Query: 201 AQAG----PHKRAVGAAAGAAQSSG----LFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
              G       R      G     G      ++ +P  P      G +    P  L   +
Sbjct: 440 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499

Query: 253 SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
            PR   G         G     G RG   DG P+         G  G++  QG PG   Q
Sbjct: 500 GPRGLLG----PKGPPGIPGPPGVRG--MDG-PQ---------GPKGSLGPQGEPGPPGQ 543

Query: 313 CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH 372
              PG  G   P     +   G  G    QG PG      +PG  G+  P         H
Sbjct: 544 QGTPGTQGLPGP-----QGAIGPHGEKGPQGKPG------LPGMPGSDGP-------PGH 585

Query: 373 PKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG 404
           P     PG+    G   P G Q P    GP G
Sbjct: 586 PGKEGPPGTK---GNQGPSGPQGPLGYPGPRG 614



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 75/279 (26%), Positives = 87/279 (31%), Gaps = 46/279 (16%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            P G P  P P G  GPR   G+   RG  G   + G        P G       +  R  
Sbjct: 1161 PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG-----SPGPTGENGPPGPLGKRGP 1215

Query: 203  AG-PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGA 260
            AG P         GA    G         P    P GP  P+ +P        P      
Sbjct: 1216 AGSPGSEGRQGGKGAKGDPGAIG-----APGKTGPVGPAGPAGKPGPDGLRGLP-----G 1265

Query: 261  GHSQTWRQGAGEAQGTRGG-SADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGAS 319
               Q  R GA    G  G     G+P L        G  G    +G PG       PG  
Sbjct: 1266 SVGQQGRPGATGQAGPPGPVGPPGLPGLR-------GDAGAKGEKGHPGLIGLIGPPGEQ 1318

Query: 320  GTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSP 379
            G +           G  G    QG PG   E  +PGA G   PI   G     P G   P
Sbjct: 1319 GEK-----------GDRGLPGPQGSPGQKGEMGIPGASG---PIGPGG-----PPGLPGP 1359

Query: 380  GSSPGF-GELWPLGQQCPCVAQGPHG-GGKPSQALAAGP 416
                G  G   P G +     QGP G  G P + +   P
Sbjct: 1360 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1398



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 76/304 (25%), Positives = 96/304 (31%), Gaps = 49/304 (16%)

Query: 135  LAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGL--------CCAHPVR 186
            + +Q    PPG P    P G  G     G     GP G   + GL            P  
Sbjct: 805  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 864

Query: 187  PAGHVACG-AGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSR 244
            P      G AG+    +  P +R +   AG     G           ++ P+GP  P+  
Sbjct: 865  PGAPGKDGPAGL----RGFPGERGLPGTAGGPGLKG-----------NEGPSGPPGPAGS 909

Query: 245  PHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQ 304
            P     A S  P    G  +   QG   A G +G   +  P     +    G  G     
Sbjct: 910  PGERGAAGSGGPIGPPG--RPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPA 967

Query: 305  GPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIA 364
            GPPG   +    G  G      T+     G  G     GPPG       PGA G      
Sbjct: 968  GPPGVAGEDGDKGEVGDPGQKGTK-----GNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1022

Query: 365  ARG-------------RYRSHPKGNCS----PGSSPGFGELWPLGQQCPCVAQGPHGGGK 407
            ARG             R  + P G       PG S   GE   +G   P    GP G   
Sbjct: 1023 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAG 1082

Query: 408  PSQA 411
            P+ A
Sbjct: 1083 PNGA 1086



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 76/295 (25%), Positives = 96/295 (32%), Gaps = 61/295 (20%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
           PPG    P P G  G R   G +   G  G+    G     P R       G G      
Sbjct: 305 PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR----FGSGGG-----D 355

Query: 203 AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA--------SP 254
            GP   A  A A A       +   P  P+  +   P P  +P +              P
Sbjct: 356 KGPVVAAQEAQAQAILQQARLALRGPPGPMG-YTGRPGPLGQPGSPGLKGESGDLGPQGP 414

Query: 255 RPCWG--AGHSQTWRQGAGEAQGTRG----------GSADGIPELTCYQRSKCGKCGTVP 302
           R   G      +  R+G   A G RG             DG+P L   ++   G  G   
Sbjct: 415 RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLP-GEKGHRGDTGAQG 473

Query: 303 TQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSP 362
             GPPG + +    G  G R         + G  G +  +GPPG      +PG  G    
Sbjct: 474 LPGPPGEDGERGDDGEIGPRG-----LPGESGPRGLLGPKGPPG------IPGPPGVRGM 522

Query: 363 IAARGRYRSHPKGNCSPGSSPGFGELWPLGQQ---------CPCVAQGPHGGGKP 408
              +G     PKG+  P   PG     P GQQ          P  A GPHG   P
Sbjct: 523 DGPQG-----PKGSLGPQGEPG-----PPGQQGTPGTQGLPGPQGAIGPHGEKGP 567



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 82/319 (25%), Positives = 102/319 (31%), Gaps = 58/319 (18%)

Query: 140 PQKPPGGP-QRPSPG--GLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAG 196
           PQ  PG P Q+ +PG  GL GP+   G    +GPQG     G+  +    P GH      
Sbjct: 534 PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG--PPGHPGKEGP 591

Query: 197 IWTRAQAGP--------------------------HKRAVGAAAGAAQSSGLFSKWVPCQ 230
             T+   GP                          HK   G          +  K    +
Sbjct: 592 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 651

Query: 231 ---PLSQHPTGPE-PSSRPHALSTAASPRPCWGAGH-SQTWRQGAGEAQGTRGGSA-DGI 284
              P S+   GPE P  R         P      G        G    QG +G     G 
Sbjct: 652 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 711

Query: 285 PELTCYQ--RSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQ 342
           P  +  +  R   GK G    +GP G   Q    GA+G           K G  GT    
Sbjct: 712 PGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG-----------KSGAKGTSGGD 760

Query: 343 GPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGF-GELWPLGQQCPCVAQG 401
           GP G   E  +PG  G +     +G     P G       PG  G+   +G Q      G
Sbjct: 761 GPHGPPGERGLPGPQGPNGFPGPKG-----PPGPPGKDGLPGHPGQRGEVGFQGKTGPPG 815

Query: 402 PHGGGKPSQALAAGPTVSM 420
           P G   P    AAG T  M
Sbjct: 816 PPGVVGPQG--AAGETGPM 832


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 100/365 (27%), Positives = 125/365 (34%), Gaps = 48/365 (13%)

Query: 143  PPGGPQRPSPGGLR---GPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAG----HVACGA 195
            PPG P +  P GLR   G R L G++   G +G+   SG     P  PAG      A G+
Sbjct: 971  PPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG-----PPGPAGSPGERGAAGS 1025

Query: 196  GIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR 255
            G        P  +    AAG         K VP +     PTG +    P  L   A P 
Sbjct: 1026 GGPIGPPGRPGPQGPPGAAG--------EKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP- 1076

Query: 256  PCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAM 315
            P            G    +GT+G   +  P          G  G +   G PG       
Sbjct: 1077 PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPP---------GPPGPIGPVGQPGAAGADGE 1127

Query: 316  PGASGTRSPIATR----RRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYR 370
            PGA G +     +     R   G  G +  QG PG   E    G  G   P    G R  
Sbjct: 1128 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP 1187

Query: 371  SHPKGNCSPGSSP-GFGELWPLGQQC-PCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQG 428
            + P G   P   P G G L P G++  P  +  P   G+P      GP     G R  +G
Sbjct: 1188 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPG---VKGPR----GERGEKG 1240

Query: 429  WSRSLLPKWPPATLW-LGDDLFTGS---CHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWG 484
             S       PP      GDD   G+     FP   G          +G  G R   G  G
Sbjct: 1241 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1300

Query: 485  ETQSP 489
            +  SP
Sbjct: 1301 QPGSP 1305



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 95/361 (26%), Positives = 122/361 (33%), Gaps = 81/361 (22%)

Query: 90   AGGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQR 149
            AGGPG    EG +  P   G             G R A  +G        P  PPG P  
Sbjct: 996  AGGPGLKGNEGPSGPPGPAGSP-----------GERGAAGSG-------GPIGPPGRPGP 1037

Query: 150  PSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPV---RPAGHVACGAGIWTRAQAG-P 205
              P G  G + + G    +GP G   + G+    PV    PAG          + + G P
Sbjct: 1038 QGPPGAAGEKGVPGE---KGPIGPTGRDGV--QGPVGLPGPAGPPGVAGEDGDKGEVGDP 1092

Query: 206  HKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGP-EPSSRPHALSTAASPRPCWGAGHSQ 264
             ++      G     G              P GP  P  +P A      P      GH  
Sbjct: 1093 GQKGTKGNKGEHGPPG--------------PPGPIGPVGQPGAAGADGEPGARGPQGHF- 1137

Query: 265  TWRQGAGEAQGTRGGSA-------DGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPG 317
                GA   +GTRG +         G+P     ++ + G  G +   GPPG        G
Sbjct: 1138 ----GAKGDEGTRGFNGPPGPIGLQGLPG-PSGEKGETGDVGPMGPPGPPGPRGPAGPNG 1192

Query: 318  ASGTRSPIA-------TRRRSKCGKCGTVTAQGPPGT---------HAECAMPGAGGTHS 361
            A G + P            + + G+ G+   QG PG            E   PG  G   
Sbjct: 1193 ADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1252

Query: 362  PIAARGRYRSHPKGNCSPGSSPGF----GELWPLGQQCPCVAQGPHG-GGKPSQALAAGP 416
            P    G     PKGN  P   PG     GE  P GQ     A+G  G  G+P Q  + GP
Sbjct: 1253 PKGPTG--DDGPKGNPGPVGFPGDPGPPGEGGPRGQD---GAKGDRGEDGEPGQPGSPGP 1307

Query: 417  T 417
            T
Sbjct: 1308 T 1308



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 75/280 (26%), Positives = 87/280 (31%), Gaps = 38/280 (13%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
            PQ P G P    P G  G   L G    RG  G   K+G     P  P G V        
Sbjct: 881  PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG-----PPGPPGVVGPQGAAGE 935

Query: 200  RAQAG----------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHAL- 248
                G          P ++ +   AG   + G      P  P    P G         L 
Sbjct: 936  TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG--DPGPPGAPGKDGPAGLRGFPGERGLP 993

Query: 249  STAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPG 308
             TA  P      G S     G   + G RG +  G P          G  G    QGPPG
Sbjct: 994  GTAGGPGLKGNEGPSGP--PGPAGSPGERGAAGSGGP---------IGPPGRPGPQGPPG 1042

Query: 309  TNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGR 368
               +  +PG  G   P  T R    G  G     GPPG   E    G  G       +G 
Sbjct: 1043 AAGEKGVPGEKGPIGP--TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGN 1100

Query: 369  YRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKP 408
                 KG   P   P  G + P+GQ     A G  G   P
Sbjct: 1101 -----KGEHGPPGPP--GPIGPVGQPGAAGADGEPGARGP 1133



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 75/276 (27%), Positives = 92/276 (33%), Gaps = 46/276 (16%)

Query: 144  PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
            P GP  P   GL GP+  +G    +GP G   K GL         GH      +  + + 
Sbjct: 869  PHGP--PGERGLPGPQGPNGFPGPKGPPGPPGKDGL--------PGHPGQRGEVGFQGKT 918

Query: 204  GPH-KRAVGAAAGAAQSSGLFSKWVPCQPLSQ--HPTGPEPSSRPHALSTAASPRPCWGA 260
            GP     V    GAA  +G         P+ +  HP  P P        TA         
Sbjct: 919  GPPGPPGVVGPQGAAGETG---------PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 969

Query: 261  GHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGAS 319
            G       G     G RG   + G+P          G  G     GPPG        GA+
Sbjct: 970  GPPGA--PGKDGPAGLRGFPGERGLPGTA----GGPGLKGNEGPSGPPGPAGSPGERGAA 1023

Query: 320  GTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSP 379
            G+  PI        G  G    QGPPG   E  +PG  G   P    G     P G   P
Sbjct: 1024 GSGGPI--------GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDG--VQGPVGLPGP 1073

Query: 380  GSSPGF-------GELWPLGQQCPCVAQGPHGGGKP 408
               PG        GE+   GQ+     +G HG   P
Sbjct: 1074 AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGP 1109



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 88/332 (26%), Positives = 102/332 (30%), Gaps = 57/332 (17%)

Query: 91  GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFEL----------LAWQHP 140
           G PG     G   AP   G    L    G G G +    A  E           LA + P
Sbjct: 429 GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGP 488

Query: 141 QKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTR 200
             P G   RP P G  G   L G S   GPQG     GL    P   AG          R
Sbjct: 489 PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL--TGPPGKAGRRGRAGADGAR 546

Query: 201 AQAG----PHKRAVGAAAGAAQSSG----LFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
              G       R      G     G      ++ +P  P      G +    P  L   +
Sbjct: 547 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 606

Query: 253 SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
            PR   G         G     G RG   DG P+         G  G++  QG PG   Q
Sbjct: 607 GPRGLLG----PKGPPGIPGPPGVRG--MDG-PQ---------GPKGSLGPQGEPGPPGQ 650

Query: 313 CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH 372
              PG  G   P     +   G  G    QG PG      +PG  G+  P         H
Sbjct: 651 QGTPGTQGLPGP-----QGAIGPHGEKGPQGKPG------LPGMPGSDGP-------PGH 692

Query: 373 PKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG 404
           P     PG+    G   P G Q P    GP G
Sbjct: 693 PGKEGPPGTK---GNQGPSGPQGPLGYPGPRG 721



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 75/279 (26%), Positives = 87/279 (31%), Gaps = 46/279 (16%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            P G P  P P G  GPR   G+   RG  G   + G        P G       +  R  
Sbjct: 1268 PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG-----SPGPTGENGPPGPLGKRGP 1322

Query: 203  AG-PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGA 260
            AG P         GA    G         P    P GP  P+ +P        P      
Sbjct: 1323 AGSPGSEGRQGGKGAKGDPGAIG-----APGKTGPVGPAGPAGKPGPDGLRGLP-----G 1372

Query: 261  GHSQTWRQGAGEAQGTRGG-SADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGAS 319
               Q  R GA    G  G     G+P L        G  G    +G PG       PG  
Sbjct: 1373 SVGQQGRPGATGQAGPPGPVGPPGLPGLR-------GDAGAKGEKGHPGLIGLIGPPGEQ 1425

Query: 320  GTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSP 379
            G +           G  G    QG PG   E  +PGA G   PI   G     P G   P
Sbjct: 1426 GEK-----------GDRGLPGPQGSPGQKGEMGIPGASG---PIGPGG-----PPGLPGP 1466

Query: 380  GSSPGF-GELWPLGQQCPCVAQGPHG-GGKPSQALAAGP 416
                G  G   P G +     QGP G  G P + +   P
Sbjct: 1467 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1505



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 76/304 (25%), Positives = 96/304 (31%), Gaps = 49/304 (16%)

Query: 135  LAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGL--------CCAHPVR 186
            + +Q    PPG P    P G  G     G     GP G   + GL            P  
Sbjct: 912  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 971

Query: 187  PAGHVACG-AGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSR 244
            P      G AG+    +  P +R +   AG     G           ++ P+GP  P+  
Sbjct: 972  PGAPGKDGPAGL----RGFPGERGLPGTAGGPGLKG-----------NEGPSGPPGPAGS 1016

Query: 245  PHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQ 304
            P     A S  P    G  +   QG   A G +G   +  P     +    G  G     
Sbjct: 1017 PGERGAAGSGGPIGPPG--RPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPA 1074

Query: 305  GPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIA 364
            GPPG   +    G  G      T+     G  G     GPPG       PGA G      
Sbjct: 1075 GPPGVAGEDGDKGEVGDPGQKGTK-----GNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1129

Query: 365  ARG-------------RYRSHPKGNCS----PGSSPGFGELWPLGQQCPCVAQGPHGGGK 407
            ARG             R  + P G       PG S   GE   +G   P    GP G   
Sbjct: 1130 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAG 1189

Query: 408  PSQA 411
            P+ A
Sbjct: 1190 PNGA 1193



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 76/295 (25%), Positives = 96/295 (32%), Gaps = 61/295 (20%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
           PPG    P P G  G R   G +   G  G+    G     P R       G G      
Sbjct: 412 PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR----FGSGGG-----D 462

Query: 203 AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA--------SP 254
            GP   A  A A A       +   P  P+  +   P P  +P +              P
Sbjct: 463 KGPVVAAQEAQAQAILQQARLALRGPPGPMG-YTGRPGPLGQPGSPGLKGESGDLGPQGP 521

Query: 255 RPCWG--AGHSQTWRQGAGEAQGTRG----------GSADGIPELTCYQRSKCGKCGTVP 302
           R   G      +  R+G   A G RG             DG+P L   ++   G  G   
Sbjct: 522 RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLP-GEKGHRGDTGAQG 580

Query: 303 TQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSP 362
             GPPG + +    G  G R         + G  G +  +GPPG      +PG  G    
Sbjct: 581 LPGPPGEDGERGDDGEIGPRG-----LPGESGPRGLLGPKGPPG------IPGPPGVRGM 629

Query: 363 IAARGRYRSHPKGNCSPGSSPGFGELWPLGQQ---------CPCVAQGPHGGGKP 408
              +G     PKG+  P   PG     P GQQ          P  A GPHG   P
Sbjct: 630 DGPQG-----PKGSLGPQGEPG-----PPGQQGTPGTQGLPGPQGAIGPHGEKGP 674



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 82/319 (25%), Positives = 102/319 (31%), Gaps = 58/319 (18%)

Query: 140 PQKPPGGP-QRPSPG--GLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAG 196
           PQ  PG P Q+ +PG  GL GP+   G    +GPQG     G+  +    P GH      
Sbjct: 641 PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG--PPGHPGKEGP 698

Query: 197 IWTRAQAGP--------------------------HKRAVGAAAGAAQSSGLFSKWVPCQ 230
             T+   GP                          HK   G          +  K    +
Sbjct: 699 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 758

Query: 231 ---PLSQHPTGPE-PSSRPHALSTAASPRPCWGAGH-SQTWRQGAGEAQGTRGGSA-DGI 284
              P S+   GPE P  R         P      G        G    QG +G     G 
Sbjct: 759 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 818

Query: 285 PELTCYQ--RSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQ 342
           P  +  +  R   GK G    +GP G   Q    GA+G           K G  GT    
Sbjct: 819 PGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG-----------KSGAKGTSGGD 867

Query: 343 GPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGF-GELWPLGQQCPCVAQG 401
           GP G   E  +PG  G +     +G     P G       PG  G+   +G Q      G
Sbjct: 868 GPHGPPGERGLPGPQGPNGFPGPKG-----PPGPPGKDGLPGHPGQRGEVGFQGKTGPPG 922

Query: 402 PHGGGKPSQALAAGPTVSM 420
           P G   P    AAG T  M
Sbjct: 923 PPGVVGPQG--AAGETGPM 939


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 67/246 (27%), Positives = 82/246 (33%), Gaps = 31/246 (12%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
            P+   G P  P P G++GP    G +   G +G     G    H V P G V        
Sbjct: 1152 PRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGE 1211

Query: 200  RAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWG 259
            R   G        + G +       K  P  P S  P GP       A +T  +P+    
Sbjct: 1212 RGDPG--------SPGISPPGPRGKKGPPGPPGSSGPPGP-------AGATGRAPKDIPD 1256

Query: 260  AGHSQTWRQGAGEAQGTRGG-SADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGA 318
             G      QG     G RG     G+P      R + G CG     GPPG       PG 
Sbjct: 1257 PG--PPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGP------PGP 1308

Query: 319  SGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCS 378
             G +         K G+ G V   GP G H     PG  G   P   +G     P G   
Sbjct: 1309 PGYKG--FPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKG-----PTGLPG 1361

Query: 379  PGSSPG 384
            P   PG
Sbjct: 1362 PRGEPG 1367



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 74/282 (26%), Positives = 95/282 (33%), Gaps = 53/282 (18%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            P G    P P G +GPR L G   + G +G     G  C       G          R  
Sbjct: 892  PFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEG--CPGAKGEPGEKGMSGLPGDRGL 949

Query: 203  AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE--PSSRPHALSTAASPRPCWGA 260
             G  K A+G      + + +  K  P +P    P G +  P  R                
Sbjct: 950  RGA-KGAIGPPGDEGEMAIISQKGTPGEP---GPPGDDGFPGERGD-------------- 991

Query: 261  GHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
                   +G    QG RG      P    + R + G+ G     GPPG       PG++G
Sbjct: 992  -------KGTPGMQGRRGEPGRYGP--PGFHRGEPGEKGQPGPPGPPGP------PGSTG 1036

Query: 321  TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH-----PKG 375
             R  I        G  G    QG PG+       G  G   P   +G   SH     PKG
Sbjct: 1037 LRGFI--------GFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKG 1088

Query: 376  NCSPGSSPGFGELWPLGQQCPCVAQGPHGG-GKPSQALAAGP 416
               PGS    G     G+Q     QGP G  G+P    ++GP
Sbjct: 1089 --EPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGP 1128



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 100/423 (23%), Positives = 125/423 (29%), Gaps = 45/423 (10%)

Query: 91  GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRP 150
           G PG +   G+   P       GL    G  C      P          PQ  PG P  P
Sbjct: 373 GFPGRYGETGDVGPP----GPPGLLGRPGEACAGMIGPPG---------PQGFPGLPGLP 419

Query: 151 SPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPH--KR 208
              G+ G    +   P  G  GS    G      +  +  + C  G       GP   K 
Sbjct: 420 GEAGIPGRPDSAPGKP--GKPGSPGLPGAPGLQGLPGSSVIYCSVG-----NPGPQGIKG 472

Query: 209 AVGAAAGAAQSSGLFSKWV-PCQPLSQHPTGPE--PSSR--------PHALSTAASPRPC 257
            VG   G        ++ +  C+P    P GP   P  +        P  L T   P P 
Sbjct: 473 KVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPP 532

Query: 258 WGAGH-SQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMP 316
              G      + GA    G +G   D +       + + G  G     G PG++ +    
Sbjct: 533 GAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHA 592

Query: 317 GASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGN 376
           G  G   P      +  G  G     GPPG       PG G    P       R HP   
Sbjct: 593 GEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPP-----GERGHPGVP 647

Query: 377 CSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLPK 436
             PG     G     G    C    P   G P      GP     G +   G S S   K
Sbjct: 648 GHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPK-GFPGPQGAPGLSGSDGHK 706

Query: 437 WPPATLWL----GDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSPEAG 492
             P T       G   F G    P   G++  SP +   G  G     G  G    P  G
Sbjct: 707 GRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSP-VGPPGPPGSPGVNGQKGIPGDPAFG 765

Query: 493 AQG 495
             G
Sbjct: 766 HLG 768



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 92/390 (23%), Positives = 120/390 (30%), Gaps = 72/390 (18%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAG--------HV 191
           P  P  GP  P   G  G    +G     GP G L + G  CA  + P G         +
Sbjct: 361 PPLPLKGP--PGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGL 418

Query: 192 ACGAGIWTRAQAGPHKRAVGAAAGAAQSSGL----FSKWVPCQPLSQHP------TGPEP 241
              AGI  R  + P K     + G   + GL     S  + C   +  P       GP  
Sbjct: 419 PGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPG 478

Query: 242 SSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTV 301
              P           C           G    QG++G    G+P          G  GT 
Sbjct: 479 GRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDL--GLP----------GWLGTK 526

Query: 302 PTQGPPGTNPQCAMPGASGTRSPIATR-------------RRSKCGKCGTVTAQGPPGTH 348
              GPPG      +PG  G   P   +              + + G  G     G PG+H
Sbjct: 527 GDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSH 586

Query: 349 ------AECAMPGAGGTHSPIAARGR---YRSHPKGNCSPGSSPGFGELWPLGQQCPCVA 399
                  E   PG  G H      G+       P G   P   PG G   P G++     
Sbjct: 587 GRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGER----- 641

Query: 400 QGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSF 459
                 G P      GP     G++  +G + S    +P      G D   G   FP   
Sbjct: 642 ---GHPGVPGHPGVRGPD----GLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQ 694

Query: 460 GQRCLSPSIQTNGGDGQRRSGGSWGETQSP 489
           G   LS      G DG +   G+ G  + P
Sbjct: 695 GAPGLS------GSDGHKGRPGTPGTAEIP 718



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 74/279 (26%), Positives = 85/279 (30%), Gaps = 41/279 (14%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVR-PAGHVACGAGIW--T 199
            PPG P  P   GLRG     G    +G  GS    G       R P G+    A  +   
Sbjct: 1025 PPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP 1084

Query: 200  RAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWG 259
              +  P         GA+   GL        P  Q P G      P   S    P  C G
Sbjct: 1085 GPKGEPGSPGCPGHFGASGEQGL--------PGIQGPRGSPGRPGPPGSS---GPPGCPG 1133

Query: 260  AGHSQTWRQGAGEA--QGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMP 316
                   R   GE    G RG   D GIP          G  G     G PG N    + 
Sbjct: 1134 DHGMPGLRGQPGEMGDPGPRGLQGDPGIP----------GPPGIKGPSGSPGLNGLHGLK 1183

Query: 317  GASGTRSPIATRRRSKCGKCGTVTAQG-----------PPGTHAECAMPGAGGTHSPIAA 365
            G  GT+           G  G    +G           PPG   +   PG  G+  P   
Sbjct: 1184 GQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGP 1243

Query: 366  RGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG 404
             G     PK    PG     G+  P G   P  A GP G
Sbjct: 1244 AGATGRAPKDIPDPGPP---GDQGPPGPDGPRGAPGPPG 1279



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 88/350 (25%), Positives = 107/350 (30%), Gaps = 47/350 (13%)

Query: 91   GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFE-LLAWQHPQKPPGGPQR 149
            G PG     G    P   G  SGL    G+        P G E  +A    +  PG P  
Sbjct: 921  GKPGAEGCPGAKGEPGEKGM-SGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGP 979

Query: 150  PSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHKRA 209
            P   G  G R   G+   +G +G   + G    H   P            + Q GP    
Sbjct: 980  PGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPG----------EKGQPGPP--- 1026

Query: 210  VGAAAGAAQSSGLFSK-WVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQ 268
                 G   S+GL      P  P  Q   G         +  A  P+   G   S     
Sbjct: 1027 --GPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP 1084

Query: 269  GAGEAQGTRG-------GSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGT 321
            G     G+ G           G+P +    R   G+ G   + GPPG      MPG  G 
Sbjct: 1085 GPKGEPGSPGCPGHFGASGEQGLPGIQG-PRGSPGRPGPPGSSGPPGCPGDHGMPGLRG- 1142

Query: 322  RSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHS------PIAARGRYRSHP-- 373
              P         G  G     GPPG       PG  G H          A G +   P  
Sbjct: 1143 -QPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPG 1201

Query: 374  -------KGNCSPGSSPGFGELWPLGQQCPCVAQGPHG-GGKPSQALAAG 415
                   KG      SPG     P G++ P    GP G  G P  A A G
Sbjct: 1202 PVGIPGLKGERGDPGSPGISPPGPRGKKGP---PGPPGSSGPPGPAGATG 1248



 Score = 36.6 bits (83), Expect = 0.088
 Identities = 69/271 (25%), Positives = 85/271 (31%), Gaps = 59/271 (21%)

Query: 145 GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG 204
           G P  P P G RG   +SG +  RG  G     G     P  P GH         + + G
Sbjct: 122 GIPGHPGPPGPRGKPGMSGHNGSRGDPG--FPGGRGALGPGGPLGHPG------EKGEKG 173

Query: 205 PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGAGHS 263
                +GA  G     G     +P  P S    GP  P+  P        P         
Sbjct: 174 NSVFILGAVKGIQGDRG--DPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPP--------- 222

Query: 264 QTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTN------PQCAMPG 317
                G     G +G    G+       + + G  G V  QG PG          C   G
Sbjct: 223 -----GQPGRPGLKGNPGVGV-------KGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKG 270

Query: 318 ASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNC 377
             G +           G  G V   GPPG   E  + GA G        G     P+G+ 
Sbjct: 271 EKGIK-----------GIPGMVGLPGPPGRKGESGI-GAKGEKGIPGFPG-----PRGDP 313

Query: 378 SPGSSPGF----GELWPLGQQCPCVAQGPHG 404
               SPGF    GEL  +G        GP G
Sbjct: 314 GSYGSPGFPGLKGELGLVGDPGLFGLIGPKG 344



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 33/118 (27%), Positives = 41/118 (34%), Gaps = 8/118 (6%)

Query: 305 GPPGTNPQCAMPGASGTR-SPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPI 363
           GPPG      +PG  G R  P         G  G +  +GP G       PG  G     
Sbjct: 768 GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHS 827

Query: 364 AARGR-----YRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGP 416
             RG          P    SPG+  G G+   +G   P   +G    G P +  A GP
Sbjct: 828 CERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGL--PGLPGRPGAHGP 883



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 83/362 (22%), Positives = 114/362 (31%), Gaps = 51/362 (14%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            PPG    P P G  GP+   G S   G +G     G   A    P G            +
Sbjct: 678  PPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGT--AEIPGPPGFRGDMGDPGFGGE 735

Query: 203  AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGH 262
             G          G+   +G   K +P  P   H  GP        +     PR       
Sbjct: 736  KGSSPVGPPGPPGSPGVNG--QKGIPGDPAFGH-LGPPGKRGLSGVPGIKGPR------- 785

Query: 263  SQTWRQGAGEAQGTRGGSADGIPELTCYQ--RSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
                  G     G  G +  GIP     +  + + G  G     GPPG + +   PG  G
Sbjct: 786  ------GDPGCPGAEGPA--GIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPG 837

Query: 321  TRS----PIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-------RY 369
                   P +       G+ G V   GP G      +PG  G H P    G         
Sbjct: 838  QPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDG 897

Query: 370  RSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGW 429
               P G   P   PGF   +P  +  P     P   G+P +   +G    + G R L+G 
Sbjct: 898  LPGPPGPKGPRGLPGFPG-FPGERGKPGAEGCPGAKGEPGEKGMSG----LPGDRGLRGA 952

Query: 430  SRSLLPKWPPATLWL-------GDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGS 482
              ++ P      + +       G+    G   FP   G +       T G  G+R   G 
Sbjct: 953  KGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDK------GTPGMQGRRGEPGR 1006

Query: 483  WG 484
            +G
Sbjct: 1007 YG 1008


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
           sapiens]
          Length = 1818

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 82/271 (30%), Positives = 91/271 (33%), Gaps = 46/271 (16%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWR-GPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRA 201
           PPG P  P   GL GP       P+R G  GS    G   +     A  +   A I  R 
Sbjct: 485 PPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS---KGPTISAQEAQAQAILQQARIALRG 541

Query: 202 QAGP-HKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTG----PEPSSRPHALSTAASPRP 256
             GP          G   SSG  +K     P  Q P G    P P+ +P         RP
Sbjct: 542 PPGPMGLTGRPGPVGGPGSSG--AKGESGDPGPQGPRGVQGPPGPTGKP-----GKRGRP 594

Query: 257 CWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMP 316
               G       G   A+G RG   DG+P L        G  G    QGPPG      M 
Sbjct: 595 GADGGRGMPGEPG---AKGDRG--FDGLPGLP----GDKGHRGERGPQGPPGPPGDDGMR 645

Query: 317 GASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGN 376
           G  G   P     R   G+ G     GP GT      PG  G   P          PKGN
Sbjct: 646 GEDGEIGP-----RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP--------PGPKGN 692

Query: 377 CSPGSSPGFGELWPLGQQ---CPCVAQGPHG 404
             P   PG     P GQQ    P    GP G
Sbjct: 693 MGPQGEPG-----PPGQQGNPGPQGLPGPQG 718



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 71/276 (25%), Positives = 85/276 (30%), Gaps = 45/276 (16%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            P G P RP P G  GP    G+   +GPQG              PAG       +     
Sbjct: 1082 PIGLPGRPGPQGPPGPAGEKGAPGEKGPQG--------------PAGRDGVQGPVGLPGP 1127

Query: 203  AGP--------HKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASP 254
            AGP         K  +G                P  P  Q P G      P        P
Sbjct: 1128 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG-----APGIAGGDGEP 1182

Query: 255  RPCWGAG-HSQTWRQGAGEAQGTRGG-SADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
             P    G   Q   +GA    G  G     G+P     ++ + G  G +   GPPG    
Sbjct: 1183 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPG-PPGEKGENGDVGPMGPPGPPGPRGP 1241

Query: 313  CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH 372
                GA G + P         G  G V  +G PG       PG  G   P   RG     
Sbjct: 1242 QGPNGADGPQGP-----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE---- 1292

Query: 373  PKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKP 408
             KG   P  + G     P G + P    GP G   P
Sbjct: 1293 -KGEAGPPGAAG-----PPGAKGPPGDDGPKGNPGP 1322



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 74/276 (26%), Positives = 89/276 (32%), Gaps = 50/276 (18%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
           PPG    P P GL GP+   G    +GPQG    +GL  A    P GH            
Sbjct: 701 PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD--GPPGH------------ 746

Query: 203 AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGH 262
             P K       GA    G              P GP     P  +  A   R   G+  
Sbjct: 747 --PGKEGQSGEKGALGPPG--------------PQGPIGYPGPRGVKGADGVRGLKGS-K 789

Query: 263 SQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGP---PGTNPQC------ 313
            +    G    +G  G   D         R + G  G     GP   PG + Q       
Sbjct: 790 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 849

Query: 314 ---AMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RY 369
               +PG  G + P     +   G  G   A G  G       PG  G   P   RG R 
Sbjct: 850 GVPGLPGYPGRQGP-----KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 904

Query: 370 RSHPKGNCSP-GSSPGFGELWPLGQQCPCVAQGPHG 404
              P G   P G+S G G   P G++ P   QGP G
Sbjct: 905 ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 940



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 77/283 (27%), Positives = 92/283 (32%), Gaps = 45/283 (15%)

Query: 138  QHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSG-LCCAHPVRPAGHVACGAG 196
            Q PQ P G P    P G  G   L G    RG  G   K+G       V P G       
Sbjct: 933  QGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP 992

Query: 197  IWTRAQAG----PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
            I  R   G    P ++ +  AAG   + G              P G      P  L    
Sbjct: 993  IGERGHPGPPGPPGEQGLPGAAGKEGAKG-----------DPGPQGISGKDGPAGLRGFP 1041

Query: 253  SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTV------PTQGP 306
              R   GA       QGA   +G  G      P  +  +R   G  G +        QGP
Sbjct: 1042 GERGLPGA-------QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGP 1094

Query: 307  PGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAAR 366
            PG   +   PG  G + P         G+ G     G PG       PG  G    I   
Sbjct: 1095 PGPAGEKGAPGEKGPQGP--------AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP 1146

Query: 367  GRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGG-GKP 408
            G+  S  KG+      PG     P G Q P  A G  GG G+P
Sbjct: 1147 GQKGS--KGDKGENGPPG-----PPGLQGPVGAPGIAGGDGEP 1182



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 86/361 (23%), Positives = 99/361 (27%), Gaps = 84/361 (23%)

Query: 144  PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
            PG P      G  GP    G    RGPQG     G     P  P G V    G+  + + 
Sbjct: 1215 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG-----PQGPPGSVGSVGGVGEKGEP 1269

Query: 204  G-------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRP 256
            G       P +  VG   G     G                GP                 
Sbjct: 1270 GEAGNPGPPGEAGVGGPKGERGEKG--------------EAGPP---------------- 1299

Query: 257  CWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMP 316
                        GA    G +G   D  P      +   G  G     GPPG        
Sbjct: 1300 ------------GAAGPPGAKGPPGDDGP------KGNPGPVGFPGDPGPPGEPGPAGQD 1341

Query: 317  GASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYRSHPKG 375
            G  G +           G+ G     GPPG   E   PG  G   P  A G   R   KG
Sbjct: 1342 GVGGDK-----------GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1390

Query: 376  NCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLP 435
                  + G     P G+  P   QGP G   P         V   G+    G      P
Sbjct: 1391 AKGEAGAEG-----PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP 1445

Query: 436  KWPPATLWL-GDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSPEAGAQ 494
              PP    L GD    G    P   G       I   G  G++   G  G   SP A   
Sbjct: 1446 MGPPGLPGLKGDPGSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGD 1499

Query: 495  G 495
            G
Sbjct: 1500 G 1500



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 82/336 (24%), Positives = 104/336 (30%), Gaps = 58/336 (17%)

Query: 88   AWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGP 147
            A  GGP   R E     P       G +   G         P GF          PPG P
Sbjct: 1281 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP-----GDPGPPGEP 1335

Query: 148  QRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHK 207
                  G+ G +   G     GP G   ++G     P  P G            + GP  
Sbjct: 1336 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG-----PPGPPG------------KRGP-P 1377

Query: 208  RAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGAGHSQTW 266
             A GA     +            P    P GP+ P+ +P        P P          
Sbjct: 1378 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP---------- 1427

Query: 267  RQGAGEAQGTRGGSA-DGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPI 325
                GE QG  G +  DG P          G  G    +G PG+  +   PG  G   P 
Sbjct: 1428 ---VGE-QGLPGAAGQDGPP-------GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP- 1475

Query: 326  ATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH-PKGNCSPGSSPG 384
                + + G  G    QG PG   +  +PG  G   P    G      PKGN        
Sbjct: 1476 -PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN-------- 1526

Query: 385  FGELWPLGQQCPCVAQGPHGG-GKPSQALAAGPTVS 419
             G   P GQ+      GP G  G P + +   P +S
Sbjct: 1527 KGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILS 1562



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 97/381 (25%), Positives = 119/381 (31%), Gaps = 61/381 (16%)

Query: 138 QHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGI 197
           Q P  PPG        G  GPR L G +   GP+G L   G   A P +P G        
Sbjct: 633 QGPPGPPGDDGMRGEDGEIGPRGLPGEA---GPRGLLGPRGTPGA-PGQP-GMAGVDGPP 687

Query: 198 WTRAQAGPH-KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE----PSSRPHALSTAA 252
             +   GP  +       G     GL        P  Q P GP     P  +P       
Sbjct: 688 GPKGNMGPQGEPGPPGQQGNPGPQGL--------PGPQGPIGPPGEKGPQGKPGLAGLPG 739

Query: 253 SPRPCWGAG-HSQTWRQGAGEAQGTRG----------GSADGIPELTCYQRSKCGKCGTV 301
           +  P    G   Q+  +GA    G +G            ADG+       R   G  G  
Sbjct: 740 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV-------RGLKGSKGEK 792

Query: 302 PTQGPPGTNPQCAMPGASGTRSPIATR----RRSKCGKCGTVTAQGPPGTHAE------C 351
              G PG      + G  G    I  R         G+ G     GP G   E       
Sbjct: 793 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 852

Query: 352 AMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQA 411
            +PG  G   P  + G +   P  N   G+    G+  P GQ+ P   +G  G       
Sbjct: 853 GLPGYPGRQGPKGSTG-FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG------- 904

Query: 412 LAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTN 471
            A GPT    G    +G S    P  PP     G     G   FP   G           
Sbjct: 905 -ARGPT----GKPGPKGTSGGDGPPGPPGE--RGPQGPQGPVGFPGPKGPPGPPGKDGLP 957

Query: 472 GGDGQRRSGGSWGETQSPEAG 492
           G  GQR   G  G+T  P  G
Sbjct: 958 GHPGQRGETGFQGKTGPPGPG 978



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 83/370 (22%), Positives = 117/370 (31%), Gaps = 70/370 (18%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGL----CCAHPVRPAGHVACGA 195
            P  P G    P P G RGP   +G+   +G +G+  ++G         PV P G      
Sbjct: 1358 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1417

Query: 196  GIWTRAQAGP-HKRAVGAAAGAAQSSGLFSKWVPCQP-LSQHPTGPEPSSRPHALSTAAS 253
                R   GP  ++ +  AAG     G      P  P L   P        P  +     
Sbjct: 1418 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP--PGLPGLKGDPGSKGEKGHPGLIGLIGP 1475

Query: 254  PRPCWGAGHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
            P         +   +G    QG+ G   D GIP          G  G +   GPPG    
Sbjct: 1476 P-----GEQGEKGDRGLPGTQGSPGAKGDGGIP----------GPAGPLGPPGPPG---- 1516

Query: 313  CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH 372
              +PG  G +       +   G  G     G PG       PG      PI +  + R H
Sbjct: 1517 --LPGPQGPKG-----NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRH 1569

Query: 373  PKG----------NCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCG 422
             +G          + S G    FG L  L Q    +        K        P  +   
Sbjct: 1570 TEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHM--------KFPMGTQTNPARTCKD 1621

Query: 423  MRPLQGWSRSLLPKWPPATLWL------GDDLFTGSCHFPSSFGQRCLSPSIQTNG---G 473
            ++          P +P    W+        D F   C+F S  G+ C+ P  ++ G    
Sbjct: 1622 LQLSH-------PDFPDGEYWIDPNQGCSGDSFKVYCNFTSG-GETCIYPDKKSEGVRIS 1673

Query: 474  DGQRRSGGSW 483
               +   GSW
Sbjct: 1674 SWPKEKPGSW 1683



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 68/230 (29%), Positives = 74/230 (32%), Gaps = 52/230 (22%)

Query: 296 GKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMP- 354
           G  G     GPPG       PG  G R P       + G  G     GPPGT        
Sbjct: 457 GPAGPAGIMGPPGLQGPTGPPGDPGDRGP-----PGRPGLPGADGLPGPPGTMLMLPFRY 511

Query: 355 GAGGTHSP-----------------IAARG-------RYRSHPKGNCSPGSSPGFGELWP 390
           G  G+  P                 IA RG         R  P G   PGSS   GE   
Sbjct: 512 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVG--GPGSSGAKGESGD 569

Query: 391 LGQQCPCVAQGPHG-GGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLF 449
            G Q P   QGP G  GKP +             RP     R  +P  P A    GD  F
Sbjct: 570 PGPQGPRGVQGPPGPTGKPGKR-----------GRPGADGGRG-MPGEPGAK---GDRGF 614

Query: 450 TGSCHFPSS---FGQRCLSPSIQTNGGDGQRRSGGSWGETQSP-EAGAQG 495
            G    P      G+R         G DG R   G  G    P EAG +G
Sbjct: 615 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 664


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
           sapiens]
          Length = 1767

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 82/271 (30%), Positives = 91/271 (33%), Gaps = 46/271 (16%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWR-GPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRA 201
           PPG P  P   GL GP       P+R G  GS    G   +     A  +   A I  R 
Sbjct: 434 PPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS---KGPTISAQEAQAQAILQQARIALRG 490

Query: 202 QAGP-HKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTG----PEPSSRPHALSTAASPRP 256
             GP          G   SSG  +K     P  Q P G    P P+ +P         RP
Sbjct: 491 PPGPMGLTGRPGPVGGPGSSG--AKGESGDPGPQGPRGVQGPPGPTGKP-----GKRGRP 543

Query: 257 CWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMP 316
               G       G   A+G RG   DG+P L        G  G    QGPPG      M 
Sbjct: 544 GADGGRGMPGEPG---AKGDRG--FDGLPGLP----GDKGHRGERGPQGPPGPPGDDGMR 594

Query: 317 GASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGN 376
           G  G   P     R   G+ G     GP GT      PG  G   P          PKGN
Sbjct: 595 GEDGEIGP-----RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP--------PGPKGN 641

Query: 377 CSPGSSPGFGELWPLGQQ---CPCVAQGPHG 404
             P   PG     P GQQ    P    GP G
Sbjct: 642 MGPQGEPG-----PPGQQGNPGPQGLPGPQG 667



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 71/276 (25%), Positives = 85/276 (30%), Gaps = 45/276 (16%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            P G P RP P G  GP    G+   +GPQG              PAG       +     
Sbjct: 1031 PIGLPGRPGPQGPPGPAGEKGAPGEKGPQG--------------PAGRDGVQGPVGLPGP 1076

Query: 203  AGP--------HKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASP 254
            AGP         K  +G                P  P  Q P G      P        P
Sbjct: 1077 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG-----APGIAGGDGEP 1131

Query: 255  RPCWGAG-HSQTWRQGAGEAQGTRGG-SADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
             P    G   Q   +GA    G  G     G+P     ++ + G  G +   GPPG    
Sbjct: 1132 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPG-PPGEKGENGDVGPMGPPGPPGPRGP 1190

Query: 313  CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH 372
                GA G + P         G  G V  +G PG       PG  G   P   RG     
Sbjct: 1191 QGPNGADGPQGP-----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE---- 1241

Query: 373  PKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKP 408
             KG   P  + G     P G + P    GP G   P
Sbjct: 1242 -KGEAGPPGAAG-----PPGAKGPPGDDGPKGNPGP 1271



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 74/276 (26%), Positives = 89/276 (32%), Gaps = 50/276 (18%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
           PPG    P P GL GP+   G    +GPQG    +GL  A    P GH            
Sbjct: 650 PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD--GPPGH------------ 695

Query: 203 AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGH 262
             P K       GA    G              P GP     P  +  A   R   G+  
Sbjct: 696 --PGKEGQSGEKGALGPPG--------------PQGPIGYPGPRGVKGADGVRGLKGS-K 738

Query: 263 SQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGP---PGTNPQC------ 313
            +    G    +G  G   D         R + G  G     GP   PG + Q       
Sbjct: 739 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 798

Query: 314 ---AMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RY 369
               +PG  G + P     +   G  G   A G  G       PG  G   P   RG R 
Sbjct: 799 GVPGLPGYPGRQGP-----KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 853

Query: 370 RSHPKGNCSP-GSSPGFGELWPLGQQCPCVAQGPHG 404
              P G   P G+S G G   P G++ P   QGP G
Sbjct: 854 ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 889



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 77/283 (27%), Positives = 92/283 (32%), Gaps = 45/283 (15%)

Query: 138  QHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSG-LCCAHPVRPAGHVACGAG 196
            Q PQ P G P    P G  G   L G    RG  G   K+G       V P G       
Sbjct: 882  QGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP 941

Query: 197  IWTRAQAG----PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
            I  R   G    P ++ +  AAG   + G              P G      P  L    
Sbjct: 942  IGERGHPGPPGPPGEQGLPGAAGKEGAKG-----------DPGPQGISGKDGPAGLRGFP 990

Query: 253  SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTV------PTQGP 306
              R   GA       QGA   +G  G      P  +  +R   G  G +        QGP
Sbjct: 991  GERGLPGA-------QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGP 1043

Query: 307  PGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAAR 366
            PG   +   PG  G + P         G+ G     G PG       PG  G    I   
Sbjct: 1044 PGPAGEKGAPGEKGPQGP--------AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP 1095

Query: 367  GRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGG-GKP 408
            G+  S  KG+      PG     P G Q P  A G  GG G+P
Sbjct: 1096 GQKGS--KGDKGENGPPG-----PPGLQGPVGAPGIAGGDGEP 1131



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 86/361 (23%), Positives = 99/361 (27%), Gaps = 84/361 (23%)

Query: 144  PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
            PG P      G  GP    G    RGPQG     G     P  P G V    G+  + + 
Sbjct: 1164 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG-----PQGPPGSVGSVGGVGEKGEP 1218

Query: 204  G-------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRP 256
            G       P +  VG   G     G                GP                 
Sbjct: 1219 GEAGNPGPPGEAGVGGPKGERGEKG--------------EAGPP---------------- 1248

Query: 257  CWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMP 316
                        GA    G +G   D  P      +   G  G     GPPG        
Sbjct: 1249 ------------GAAGPPGAKGPPGDDGP------KGNPGPVGFPGDPGPPGEPGPAGQD 1290

Query: 317  GASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYRSHPKG 375
            G  G +           G+ G     GPPG   E   PG  G   P  A G   R   KG
Sbjct: 1291 GVGGDK-----------GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1339

Query: 376  NCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLP 435
                  + G     P G+  P   QGP G   P         V   G+    G      P
Sbjct: 1340 AKGEAGAEG-----PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP 1394

Query: 436  KWPPATLWL-GDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSPEAGAQ 494
              PP    L GD    G    P   G       I   G  G++   G  G   SP A   
Sbjct: 1395 MGPPGLPGLKGDPGSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGD 1448

Query: 495  G 495
            G
Sbjct: 1449 G 1449



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 82/336 (24%), Positives = 104/336 (30%), Gaps = 58/336 (17%)

Query: 88   AWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGP 147
            A  GGP   R E     P       G +   G         P GF          PPG P
Sbjct: 1230 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP-----GDPGPPGEP 1284

Query: 148  QRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHK 207
                  G+ G +   G     GP G   ++G     P  P G            + GP  
Sbjct: 1285 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG-----PPGPPG------------KRGP-P 1326

Query: 208  RAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGAGHSQTW 266
             A GA     +            P    P GP+ P+ +P        P P          
Sbjct: 1327 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP---------- 1376

Query: 267  RQGAGEAQGTRGGSA-DGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPI 325
                GE QG  G +  DG P          G  G    +G PG+  +   PG  G   P 
Sbjct: 1377 ---VGE-QGLPGAAGQDGPP-------GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP- 1424

Query: 326  ATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH-PKGNCSPGSSPG 384
                + + G  G    QG PG   +  +PG  G   P    G      PKGN        
Sbjct: 1425 -PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN-------- 1475

Query: 385  FGELWPLGQQCPCVAQGPHGG-GKPSQALAAGPTVS 419
             G   P GQ+      GP G  G P + +   P +S
Sbjct: 1476 KGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILS 1511



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 97/381 (25%), Positives = 119/381 (31%), Gaps = 61/381 (16%)

Query: 138 QHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGI 197
           Q P  PPG        G  GPR L G +   GP+G L   G   A P +P G        
Sbjct: 582 QGPPGPPGDDGMRGEDGEIGPRGLPGEA---GPRGLLGPRGTPGA-PGQP-GMAGVDGPP 636

Query: 198 WTRAQAGPH-KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE----PSSRPHALSTAA 252
             +   GP  +       G     GL        P  Q P GP     P  +P       
Sbjct: 637 GPKGNMGPQGEPGPPGQQGNPGPQGL--------PGPQGPIGPPGEKGPQGKPGLAGLPG 688

Query: 253 SPRPCWGAG-HSQTWRQGAGEAQGTRG----------GSADGIPELTCYQRSKCGKCGTV 301
           +  P    G   Q+  +GA    G +G            ADG+       R   G  G  
Sbjct: 689 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV-------RGLKGSKGEK 741

Query: 302 PTQGPPGTNPQCAMPGASGTRSPIATR----RRSKCGKCGTVTAQGPPGTHAE------C 351
              G PG      + G  G    I  R         G+ G     GP G   E       
Sbjct: 742 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 801

Query: 352 AMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQA 411
            +PG  G   P  + G +   P  N   G+    G+  P GQ+ P   +G  G       
Sbjct: 802 GLPGYPGRQGPKGSTG-FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG------- 853

Query: 412 LAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTN 471
            A GPT    G    +G S    P  PP     G     G   FP   G           
Sbjct: 854 -ARGPT----GKPGPKGTSGGDGPPGPPGE--RGPQGPQGPVGFPGPKGPPGPPGKDGLP 906

Query: 472 GGDGQRRSGGSWGETQSPEAG 492
           G  GQR   G  G+T  P  G
Sbjct: 907 GHPGQRGETGFQGKTGPPGPG 927



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 83/370 (22%), Positives = 117/370 (31%), Gaps = 70/370 (18%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGL----CCAHPVRPAGHVACGA 195
            P  P G    P P G RGP   +G+   +G +G+  ++G         PV P G      
Sbjct: 1307 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1366

Query: 196  GIWTRAQAGP-HKRAVGAAAGAAQSSGLFSKWVPCQP-LSQHPTGPEPSSRPHALSTAAS 253
                R   GP  ++ +  AAG     G      P  P L   P        P  +     
Sbjct: 1367 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP--PGLPGLKGDPGSKGEKGHPGLIGLIGP 1424

Query: 254  PRPCWGAGHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
            P         +   +G    QG+ G   D GIP          G  G +   GPPG    
Sbjct: 1425 P-----GEQGEKGDRGLPGTQGSPGAKGDGGIP----------GPAGPLGPPGPPG---- 1465

Query: 313  CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH 372
              +PG  G +       +   G  G     G PG       PG      PI +  + R H
Sbjct: 1466 --LPGPQGPKG-----NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRH 1518

Query: 373  PKG----------NCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCG 422
             +G          + S G    FG L  L Q    +        K        P  +   
Sbjct: 1519 TEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHM--------KFPMGTQTNPARTCKD 1570

Query: 423  MRPLQGWSRSLLPKWPPATLWL------GDDLFTGSCHFPSSFGQRCLSPSIQTNG---G 473
            ++          P +P    W+        D F   C+F S  G+ C+ P  ++ G    
Sbjct: 1571 LQLSH-------PDFPDGEYWIDPNQGCSGDSFKVYCNFTSG-GETCIYPDKKSEGVRIS 1622

Query: 474  DGQRRSGGSW 483
               +   GSW
Sbjct: 1623 SWPKEKPGSW 1632



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 68/230 (29%), Positives = 74/230 (32%), Gaps = 52/230 (22%)

Query: 296 GKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMP- 354
           G  G     GPPG       PG  G R P       + G  G     GPPGT        
Sbjct: 406 GPAGPAGIMGPPGLQGPTGPPGDPGDRGP-----PGRPGLPGADGLPGPPGTMLMLPFRY 460

Query: 355 GAGGTHSP-----------------IAARG-------RYRSHPKGNCSPGSSPGFGELWP 390
           G  G+  P                 IA RG         R  P G   PGSS   GE   
Sbjct: 461 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVG--GPGSSGAKGESGD 518

Query: 391 LGQQCPCVAQGPHG-GGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLF 449
            G Q P   QGP G  GKP +             RP     R  +P  P A    GD  F
Sbjct: 519 PGPQGPRGVQGPPGPTGKPGKR-----------GRPGADGGRG-MPGEPGAK---GDRGF 563

Query: 450 TGSCHFPSS---FGQRCLSPSIQTNGGDGQRRSGGSWGETQSP-EAGAQG 495
            G    P      G+R         G DG R   G  G    P EAG +G
Sbjct: 564 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 613


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
           sapiens]
          Length = 1806

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 82/271 (30%), Positives = 91/271 (33%), Gaps = 46/271 (16%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWR-GPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRA 201
           PPG P  P   GL GP       P+R G  GS    G   +     A  +   A I  R 
Sbjct: 473 PPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS---KGPTISAQEAQAQAILQQARIALRG 529

Query: 202 QAGP-HKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTG----PEPSSRPHALSTAASPRP 256
             GP          G   SSG  +K     P  Q P G    P P+ +P         RP
Sbjct: 530 PPGPMGLTGRPGPVGGPGSSG--AKGESGDPGPQGPRGVQGPPGPTGKP-----GKRGRP 582

Query: 257 CWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMP 316
               G       G   A+G RG   DG+P L        G  G    QGPPG      M 
Sbjct: 583 GADGGRGMPGEPG---AKGDRG--FDGLPGLP----GDKGHRGERGPQGPPGPPGDDGMR 633

Query: 317 GASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGN 376
           G  G   P     R   G+ G     GP GT      PG  G   P          PKGN
Sbjct: 634 GEDGEIGP-----RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP--------PGPKGN 680

Query: 377 CSPGSSPGFGELWPLGQQ---CPCVAQGPHG 404
             P   PG     P GQQ    P    GP G
Sbjct: 681 MGPQGEPG-----PPGQQGNPGPQGLPGPQG 706



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 71/276 (25%), Positives = 85/276 (30%), Gaps = 45/276 (16%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            P G P RP P G  GP    G+   +GPQG              PAG       +     
Sbjct: 1070 PIGLPGRPGPQGPPGPAGEKGAPGEKGPQG--------------PAGRDGVQGPVGLPGP 1115

Query: 203  AGP--------HKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASP 254
            AGP         K  +G                P  P  Q P G      P        P
Sbjct: 1116 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG-----APGIAGGDGEP 1170

Query: 255  RPCWGAG-HSQTWRQGAGEAQGTRGG-SADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
             P    G   Q   +GA    G  G     G+P     ++ + G  G +   GPPG    
Sbjct: 1171 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPG-PPGEKGENGDVGPMGPPGPPGPRGP 1229

Query: 313  CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH 372
                GA G + P         G  G V  +G PG       PG  G   P   RG     
Sbjct: 1230 QGPNGADGPQGP-----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE---- 1280

Query: 373  PKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKP 408
             KG   P  + G     P G + P    GP G   P
Sbjct: 1281 -KGEAGPPGAAG-----PPGAKGPPGDDGPKGNPGP 1310



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 74/276 (26%), Positives = 89/276 (32%), Gaps = 50/276 (18%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
           PPG    P P GL GP+   G    +GPQG    +GL  A    P GH            
Sbjct: 689 PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD--GPPGH------------ 734

Query: 203 AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGH 262
             P K       GA    G              P GP     P  +  A   R   G+  
Sbjct: 735 --PGKEGQSGEKGALGPPG--------------PQGPIGYPGPRGVKGADGVRGLKGS-K 777

Query: 263 SQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGP---PGTNPQC------ 313
            +    G    +G  G   D         R + G  G     GP   PG + Q       
Sbjct: 778 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 837

Query: 314 ---AMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RY 369
               +PG  G + P     +   G  G   A G  G       PG  G   P   RG R 
Sbjct: 838 GVPGLPGYPGRQGP-----KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 892

Query: 370 RSHPKGNCSP-GSSPGFGELWPLGQQCPCVAQGPHG 404
              P G   P G+S G G   P G++ P   QGP G
Sbjct: 893 ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 928



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 77/283 (27%), Positives = 92/283 (32%), Gaps = 45/283 (15%)

Query: 138  QHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSG-LCCAHPVRPAGHVACGAG 196
            Q PQ P G P    P G  G   L G    RG  G   K+G       V P G       
Sbjct: 921  QGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP 980

Query: 197  IWTRAQAG----PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
            I  R   G    P ++ +  AAG   + G              P G      P  L    
Sbjct: 981  IGERGHPGPPGPPGEQGLPGAAGKEGAKG-----------DPGPQGISGKDGPAGLRGFP 1029

Query: 253  SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTV------PTQGP 306
              R   GA       QGA   +G  G      P  +  +R   G  G +        QGP
Sbjct: 1030 GERGLPGA-------QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGP 1082

Query: 307  PGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAAR 366
            PG   +   PG  G + P         G+ G     G PG       PG  G    I   
Sbjct: 1083 PGPAGEKGAPGEKGPQGP--------AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP 1134

Query: 367  GRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGG-GKP 408
            G+  S  KG+      PG     P G Q P  A G  GG G+P
Sbjct: 1135 GQKGS--KGDKGENGPPG-----PPGLQGPVGAPGIAGGDGEP 1170



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 86/361 (23%), Positives = 99/361 (27%), Gaps = 84/361 (23%)

Query: 144  PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
            PG P      G  GP    G    RGPQG     G     P  P G V    G+  + + 
Sbjct: 1203 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG-----PQGPPGSVGSVGGVGEKGEP 1257

Query: 204  G-------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRP 256
            G       P +  VG   G     G                GP                 
Sbjct: 1258 GEAGNPGPPGEAGVGGPKGERGEKG--------------EAGPP---------------- 1287

Query: 257  CWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMP 316
                        GA    G +G   D  P      +   G  G     GPPG        
Sbjct: 1288 ------------GAAGPPGAKGPPGDDGP------KGNPGPVGFPGDPGPPGEPGPAGQD 1329

Query: 317  GASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG-RYRSHPKG 375
            G  G +           G+ G     GPPG   E   PG  G   P  A G   R   KG
Sbjct: 1330 GVGGDK-----------GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1378

Query: 376  NCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLP 435
                  + G     P G+  P   QGP G   P         V   G+    G      P
Sbjct: 1379 AKGEAGAEG-----PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP 1433

Query: 436  KWPPATLWL-GDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSPEAGAQ 494
              PP    L GD    G    P   G       I   G  G++   G  G   SP A   
Sbjct: 1434 MGPPGLPGLKGDPGSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGD 1487

Query: 495  G 495
            G
Sbjct: 1488 G 1488



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 82/336 (24%), Positives = 104/336 (30%), Gaps = 58/336 (17%)

Query: 88   AWAGGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGP 147
            A  GGP   R E     P       G +   G         P GF          PPG P
Sbjct: 1269 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP-----GDPGPPGEP 1323

Query: 148  QRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHK 207
                  G+ G +   G     GP G   ++G     P  P G            + GP  
Sbjct: 1324 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG-----PPGPPG------------KRGP-P 1365

Query: 208  RAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGAGHSQTW 266
             A GA     +            P    P GP+ P+ +P        P P          
Sbjct: 1366 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP---------- 1415

Query: 267  RQGAGEAQGTRGGSA-DGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPI 325
                GE QG  G +  DG P          G  G    +G PG+  +   PG  G   P 
Sbjct: 1416 ---VGE-QGLPGAAGQDGPP-------GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP- 1463

Query: 326  ATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH-PKGNCSPGSSPG 384
                + + G  G    QG PG   +  +PG  G   P    G      PKGN        
Sbjct: 1464 -PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN-------- 1514

Query: 385  FGELWPLGQQCPCVAQGPHGG-GKPSQALAAGPTVS 419
             G   P GQ+      GP G  G P + +   P +S
Sbjct: 1515 KGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILS 1550



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 97/381 (25%), Positives = 119/381 (31%), Gaps = 61/381 (16%)

Query: 138 QHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGI 197
           Q P  PPG        G  GPR L G +   GP+G L   G   A P +P G        
Sbjct: 621 QGPPGPPGDDGMRGEDGEIGPRGLPGEA---GPRGLLGPRGTPGA-PGQP-GMAGVDGPP 675

Query: 198 WTRAQAGPH-KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE----PSSRPHALSTAA 252
             +   GP  +       G     GL        P  Q P GP     P  +P       
Sbjct: 676 GPKGNMGPQGEPGPPGQQGNPGPQGL--------PGPQGPIGPPGEKGPQGKPGLAGLPG 727

Query: 253 SPRPCWGAG-HSQTWRQGAGEAQGTRG----------GSADGIPELTCYQRSKCGKCGTV 301
           +  P    G   Q+  +GA    G +G            ADG+       R   G  G  
Sbjct: 728 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV-------RGLKGSKGEK 780

Query: 302 PTQGPPGTNPQCAMPGASGTRSPIATR----RRSKCGKCGTVTAQGPPGTHAE------C 351
              G PG      + G  G    I  R         G+ G     GP G   E       
Sbjct: 781 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 840

Query: 352 AMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQA 411
            +PG  G   P  + G +   P  N   G+    G+  P GQ+ P   +G  G       
Sbjct: 841 GLPGYPGRQGPKGSTG-FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG------- 892

Query: 412 LAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTN 471
            A GPT    G    +G S    P  PP     G     G   FP   G           
Sbjct: 893 -ARGPT----GKPGPKGTSGGDGPPGPPGE--RGPQGPQGPVGFPGPKGPPGPPGKDGLP 945

Query: 472 GGDGQRRSGGSWGETQSPEAG 492
           G  GQR   G  G+T  P  G
Sbjct: 946 GHPGQRGETGFQGKTGPPGPG 966



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 83/370 (22%), Positives = 117/370 (31%), Gaps = 70/370 (18%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGL----CCAHPVRPAGHVACGA 195
            P  P G    P P G RGP   +G+   +G +G+  ++G         PV P G      
Sbjct: 1346 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1405

Query: 196  GIWTRAQAGP-HKRAVGAAAGAAQSSGLFSKWVPCQP-LSQHPTGPEPSSRPHALSTAAS 253
                R   GP  ++ +  AAG     G      P  P L   P        P  +     
Sbjct: 1406 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP--PGLPGLKGDPGSKGEKGHPGLIGLIGP 1463

Query: 254  PRPCWGAGHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
            P         +   +G    QG+ G   D GIP          G  G +   GPPG    
Sbjct: 1464 P-----GEQGEKGDRGLPGTQGSPGAKGDGGIP----------GPAGPLGPPGPPG---- 1504

Query: 313  CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH 372
              +PG  G +       +   G  G     G PG       PG      PI +  + R H
Sbjct: 1505 --LPGPQGPKG-----NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRH 1557

Query: 373  PKG----------NCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCG 422
             +G          + S G    FG L  L Q    +        K        P  +   
Sbjct: 1558 TEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHM--------KFPMGTQTNPARTCKD 1609

Query: 423  MRPLQGWSRSLLPKWPPATLWL------GDDLFTGSCHFPSSFGQRCLSPSIQTNG---G 473
            ++          P +P    W+        D F   C+F S  G+ C+ P  ++ G    
Sbjct: 1610 LQLSH-------PDFPDGEYWIDPNQGCSGDSFKVYCNFTSG-GETCIYPDKKSEGVRIS 1661

Query: 474  DGQRRSGGSW 483
               +   GSW
Sbjct: 1662 SWPKEKPGSW 1671



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 68/230 (29%), Positives = 74/230 (32%), Gaps = 52/230 (22%)

Query: 296 GKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMP- 354
           G  G     GPPG       PG  G R P       + G  G     GPPGT        
Sbjct: 445 GPAGPAGIMGPPGLQGPTGPPGDPGDRGP-----PGRPGLPGADGLPGPPGTMLMLPFRY 499

Query: 355 GAGGTHSP-----------------IAARG-------RYRSHPKGNCSPGSSPGFGELWP 390
           G  G+  P                 IA RG         R  P G   PGSS   GE   
Sbjct: 500 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVG--GPGSSGAKGESGD 557

Query: 391 LGQQCPCVAQGPHG-GGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLF 449
            G Q P   QGP G  GKP +             RP     R  +P  P A    GD  F
Sbjct: 558 PGPQGPRGVQGPPGPTGKPGKR-----------GRPGADGGRG-MPGEPGAK---GDRGF 602

Query: 450 TGSCHFPSS---FGQRCLSPSIQTNGGDGQRRSGGSWGETQSP-EAGAQG 495
            G    P      G+R         G DG R   G  G    P EAG +G
Sbjct: 603 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 652


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 117/455 (25%), Positives = 140/455 (30%), Gaps = 71/455 (15%)

Query: 91  GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLR--TAQPAGFELLAWQHPQKPPGGPQ 148
           G PG     G    P   GRD     GV  G G+R     P G        P    G   
Sbjct: 510 GAPGPAGPRGAAGEP---GRD-----GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESG 561

Query: 149 RPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAH--PVRPAGHVACGAGIWTRAQAGPH 206
           RP P G  GPR   G   + GP+G+    G       P  P      G    T  Q  P 
Sbjct: 562 RPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPG 621

Query: 207 KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE-PSSRPHALSTAASPRPCWGAGHS-- 263
               G   G     G   + +   P +  P G       P     A +P    G G +  
Sbjct: 622 PTGPGGDKGDTGPPG--PQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGA 679

Query: 264 --QTWRQGAGEAQGTRGGSADGIPE---LTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGA 318
             +    G   A G RGG+    PE            G  GT   QG PG       PG 
Sbjct: 680 PGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGP 739

Query: 319 SGTRS----------PIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGR 368
            G +           P     R   G  G     G PG   E   PG  G   P  + G 
Sbjct: 740 KGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE 799

Query: 369 -----------YRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPT 417
                      +   P  N  PG     G     G+  P    GP GG  P     AGP 
Sbjct: 800 RGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGP-----AGPP 854

Query: 418 VSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQR 477
               G + ++G   S  P  P            G+  FP   G R L     +NG  G  
Sbjct: 855 ----GPQGVKGERGS--PGGP------------GAAGFP---GARGLPGPPGSNGNPGPP 893

Query: 478 RSGGSWGETQSPEAGAQGNHVFCVDFAISGGKEDS 512
              GS G+   P  G  GN        +SG K D+
Sbjct: 894 GPSGSPGKDGPP--GPAGNTGAPGSPGVSGPKGDA 926



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 76/282 (26%), Positives = 98/282 (34%), Gaps = 64/282 (22%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
           P G P  P P G  G     GS  ++GP G   ++G   + P  P G +           
Sbjct: 175 PAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAG--PSGPPGPPGAI---------GP 223

Query: 203 AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGH 262
           +GP        AG    SG      P +P  +   GP     P     A  P      GH
Sbjct: 224 SGP--------AGKDGESGR-----PGRPGERGLPGP-----PGIKGPAGIPGFPGMKGH 265

Query: 263 ----SQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGA 318
                +   +G   A G +G   +G+P        + G  G +  +G PG   +  +PGA
Sbjct: 266 RGFDGRNGEKGETGAPGLKG--ENGLP-------GENGAPGPMGPRGAPGERGRPGLPGA 316

Query: 319 SGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCS 378
           +G R     R     G  G     GPPGT      PGA G   P               S
Sbjct: 317 AGARGNDGAR-----GSDGQPGPPGPPGTAGFPGSPGAKGEVGPAG-------------S 358

Query: 379 PGSSPGFGELWPLGQQCPCVAQGPHG----GGKPSQALAAGP 416
           PGS+   G+    G Q    AQGP G     G P      GP
Sbjct: 359 PGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGP 400



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 98/365 (26%), Positives = 115/365 (31%), Gaps = 49/365 (13%)

Query: 145 GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSG-------LCCAHPVRPAGHVACGAGI 197
           G P  P   GL G     G+  +RGP G     G            P  P G  A G   
Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRG--AAGEPG 525

Query: 198 WTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTG----PEPSSRPHALSTAAS 253
                 GP  R +  + G   S G      P  P SQ  +G    P PS           
Sbjct: 526 RDGVPGGPGMRGMPGSPGGPGSDG-----KPGPPGSQGESGRPGPPGPSGPRGQPGVMGF 580

Query: 254 PRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQC 313
           P P            GA    G RGG     P+         GK G    QGPPG     
Sbjct: 581 PGP--------KGNDGAPGKNGERGGPGGPGPQ------GPPGKNGETGPQGPPGPTGPG 626

Query: 314 AMPGASGTRSPIATR-RRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH 372
              G +G   P   +      G  G     G PG   +   PGA G      A G  R  
Sbjct: 627 GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGE-RGP 685

Query: 373 PKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSRS 432
           P    +PG   G G   P G        G    G P    AAG T  + GM   +G   S
Sbjct: 686 PGLAGAPGLRGGAGPPGPEG--------GKGAAGPPGPPGAAG-TPGLQGMPGERGGLGS 736

Query: 433 LLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSPE-A 491
             PK        G+    G+   P   G R  +  I   G  GQ    G  G    P  A
Sbjct: 737 PGPKGDK-----GEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA 791

Query: 492 GAQGN 496
           G +G+
Sbjct: 792 GPRGS 796



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 79/302 (26%), Positives = 99/302 (32%), Gaps = 32/302 (10%)

Query: 141  QKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTR 200
            Q PPG P      G+ G R L+G     GP+GS    G+      +P  +   G     R
Sbjct: 938  QGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV-KGESGKPGANGLSG----ER 992

Query: 201  AQAGPH--KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSS----RPHALSTAASP 254
               GP       G A    +     S  +P +  S    G    +     P A      P
Sbjct: 993  GPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPP 1052

Query: 255  RPCWGAGHS-------QTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPP 307
             P   AG S            GA    G+RG      P     +  + G  G    +G P
Sbjct: 1053 GPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFP 1112

Query: 308  GTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG 367
            G       PG +G +  I +      G  G V   GPPG       PG  G   P   RG
Sbjct: 1113 GNPGAPGSPGPAGQQGAIGS--PGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRG 1170

Query: 368  RYRSHPKGNCSPGSSPGF-GELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPL 426
               S          SPG  G+  P G   P  A GP  GG  + A+A        G  P 
Sbjct: 1171 ERGSE--------GSPGHPGQPGPPG---PPGAPGPCCGGVGAAAIAGIGGEKAGGFAPY 1219

Query: 427  QG 428
             G
Sbjct: 1220 YG 1221



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 75/298 (25%), Positives = 94/298 (31%), Gaps = 21/298 (7%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSG----LCCAHPVRPAGHVACGA 195
            P  P G P +  P G  G     GS    GP+G   + G         P    G +    
Sbjct: 892  PPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAG 951

Query: 196  GIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR 255
                R  AGP        +   Q     S       LS     P P   P    TA  P 
Sbjct: 952  ITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG 1011

Query: 256  PCWGAG-HSQTWRQGAGEAQGTRG-GSADGIPELTCY--QRSKCGKCGTVPTQGPPGTNP 311
                 G      R G+   +G RG   + G P    +       G  G    +G  G   
Sbjct: 1012 RDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAG 1071

Query: 312  QCAMPGASGTR-SPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYR 370
                PG +G+R +P     R   G+ G   A G  G       PGA G+  P   +G   
Sbjct: 1072 PAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIG 1131

Query: 371  S----HPKGNCSPGSSPG----FGELWPLGQQCPCVAQGPHGG----GKPSQALAAGP 416
            S     P+G   P   PG     G   P+G   P   +G  G     G P Q    GP
Sbjct: 1132 SPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGP 1189



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 83/338 (24%), Positives = 110/338 (32%), Gaps = 37/338 (10%)

Query: 90  AGGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQR 149
           AG PG+  A+GE     + G +         G   +  +P        Q P  PPG    
Sbjct: 341 AGFPGSPGAKGEVGPAGSPGSN---------GAPGQRGEPGPQGHAGAQGPPGPPGINGS 391

Query: 150 PSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPH-KR 208
           P   G  GP  + G+    G +G    +G   A  +R         G   + + GP  +R
Sbjct: 392 PGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNG--AKGEPGPRGER 449

Query: 209 AVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAG------- 261
                 G   + G   K          P  P  +  P A     +P     AG       
Sbjct: 450 GEAGIPGVPGAKGEDGK-------DGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE 502

Query: 262 HSQTWRQGAGEAQGTRGGSA----DGIPELTCYQ--RSKCGKCGTVPTQGPPGTNPQCAM 315
                 +GA    G RG +     DG+P     +      G  G+    GPPG+  +   
Sbjct: 503 KGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGR 562

Query: 316 PGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH-PK 374
           PG  G   P    +    G  G     G PG + E   PG  G   P    G      P 
Sbjct: 563 PGPPGPSGP--RGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPP 620

Query: 375 GNCSPGSSPG-FGELWPLGQQCPCVAQGPHG-GGKPSQ 410
           G   PG   G  G   P G Q      GP G  GKP +
Sbjct: 621 GPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGE 658



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 103/382 (26%), Positives = 126/382 (32%), Gaps = 51/382 (13%)

Query: 141 QKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACG------ 194
           Q PPG P +  P G  GP    G S   GP G   +SG     P RP      G      
Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIGPS---GPAGKDGESG----RPGRPGERGLPGPPGIKG 252

Query: 195 -AGIWTRAQAGPHKRAVG--AAAGAAQSSGLFSK-WVPCQPLSQHPTGPE--PSSRPH-A 247
            AGI        H+   G     G   + GL  +  +P +  +  P GP   P  R    
Sbjct: 253 PAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPG 312

Query: 248 LSTAASPRPCWGAGHSQ-----------TWRQGAGEAQGTRGGSADGIPELTCYQRSKCG 296
           L  AA  R   GA  S                G+  A+G  G +          QR + G
Sbjct: 313 LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPG 372

Query: 297 KCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPG- 355
             G    QGPPG       PG  G   P         G  G + A+GPPG       PG 
Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIP-----GAPGLMGARGPPGPAGANGAPGL 427

Query: 356 AGGTHSPIAARGRYRSHPKGNCSPGSSPGF----GELWPLGQQCPCVAQGPHGG----GK 407
            GG   P     +    P+G       PG     GE    G      A G  G     G 
Sbjct: 428 RGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGA 487

Query: 408 PSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPS 467
           P     AGP   + G +   G   +  P  P      G+    G    P   G R +  S
Sbjct: 488 PGFRGPAGPN-GIPGEKGPAGERGAPGPAGPRGA--AGE---PGRDGVPGGPGMRGMPGS 541

Query: 468 IQTNGGDGQRRSGGSWGETQSP 489
               G DG+    GS GE+  P
Sbjct: 542 PGGPGSDGKPGPPGSQGESGRP 563



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 62/225 (27%), Positives = 77/225 (34%), Gaps = 42/225 (18%)

Query: 296 GKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRS-------------KCGKCGTVTAQ 342
           G  G     GPPGT+     PG+ G + P     ++               G  G     
Sbjct: 174 GPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGES 233

Query: 343 GPPGTHAECAMPGAGGTHSPIAARG-----RYRSHPKGNCSPG--SSPGF-GELWPLGQQ 394
           G PG   E  +PG  G   P    G      +R     N   G   +PG  GE    G+ 
Sbjct: 234 GRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN 293

Query: 395 CPCVAQGPHGG----GKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFT 450
                 GP G     G+P    AAG      G    +G      P  PP T       F 
Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGAR----GNDGARGSDGQPGPPGPPGTAG-----FP 344

Query: 451 GSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSPEAGAQG 495
           GS   P + G+   + S  +NG  GQR   G  G      AGAQG
Sbjct: 345 GS---PGAKGEVGPAGSPGSNGAPGQRGEPGPQG-----HAGAQG 381



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 63/249 (25%), Positives = 81/249 (32%), Gaps = 61/249 (24%)

Query: 295 CGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSK----CGKCGTVTAQGPPGTHAE 350
           C +  T PT+ P G  PQ    G  G   P     R+      G+ G+  + GPPG    
Sbjct: 88  CPQPPTAPTRPPNGQGPQ----GPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICES 143

Query: 351 C--------------------------AMPGAGGTHSPIAARGRYRSHPKGNCSPG--SS 382
           C                            PG  G   P    G    HP    SPG    
Sbjct: 144 CPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGT-SGHPGSPGSPGYQGP 202

Query: 383 PGF-GELWPLGQQCPCVAQGPHG----------GGKPSQALAAGPTVSMCGMRPLQGWSR 431
           PG  G+  P G   P  A GP G           G+P +    GP     G++   G   
Sbjct: 203 PGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPP----GIKGPAG--- 255

Query: 432 SLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSP-- 489
             +P +P      G D   G      + G +  +     NG  G     G+ GE   P  
Sbjct: 256 --IPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGL 313

Query: 490 --EAGAQGN 496
              AGA+GN
Sbjct: 314 PGAAGARGN 322


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 83/294 (28%), Positives = 99/294 (33%), Gaps = 33/294 (11%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           PQ PPG    P P G  G   L G    +G +G   + GL    P +P G          
Sbjct: 570 PQGPPG---LPGPPGRVGAPGLQGERGEKGTRGEKGERGL-DGFPGKP-GDTGQQGRPGP 624

Query: 200 RAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWG 259
              AGP  +      G A   G+    V  + L      P P     A     +  P   
Sbjct: 625 SGVAGP--QGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGP 682

Query: 260 AGHSQTWRQGAGEAQGTRGGSAD----GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAM 315
            G     R G    QG RG   D    GIP L   Q    G  G     GPPG      +
Sbjct: 683 EG-----RDGPPGLQGLRGKKGDMGPPGIPGLLGLQ----GPPGPPGVPGPPGPGGSPGL 733

Query: 316 PGASG-TRSPIATRRRSKCGKCGTVTAQGPPGT------HAECAMPGAGGTHSPIAARG- 367
           PG  G    P         GK G     GPPGT        E  +PG  G    I  +G 
Sbjct: 734 PGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGL 793

Query: 368 RYRSHPKGNCSPGSSPGF----GELWPLGQQCPCVAQGPHGG-GKPSQALAAGP 416
             R   KG      +PGF    GE    G++      G  G  G+  +A  AGP
Sbjct: 794 AGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGP 847



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 70/278 (25%), Positives = 93/278 (33%), Gaps = 32/278 (11%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            PPG P  P   G +G + + G     G +G   ++G     P  P      G       Q
Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAG----PPGLPGPPGIAG------PQ 1167

Query: 203  AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGH 262
                +R      G     G      P  P    P G         ++ AA P    G+  
Sbjct: 1168 GSQGERGADGEVGQKGDQG-----HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS-- 1220

Query: 263  SQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTR 322
                ++G    QG  G    GIP     +  K G+ G     G PG   +  +PG  G R
Sbjct: 1221 --PGKEGPPGPQGPSG--LPGIPG----EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGAR 1272

Query: 323  SPIATR-RRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY--RSHPKGNCSP 379
             P   +      G  G     G  G   +  +PG  G   P   +G    R  P  N SP
Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332

Query: 380  GSSPGFGELWPLGQQCPCVAQGPHGG-GKPSQALAAGP 416
            GS    GE  P G      ++G +G  G P      GP
Sbjct: 1333 GSP---GEPGPSGTPGQKGSKGENGSPGLPGFLGPRGP 1367



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 93/344 (27%), Positives = 120/344 (34%), Gaps = 47/344 (13%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC--CAHPVRPAGHVACGAGI 197
            P   PG P    P G +G R   G    +G QG     G      +P  P      GA  
Sbjct: 1154 PPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAG 1213

Query: 198  WTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTG-PEPSSRPHALSTAASPRP 256
                Q  P K       G +   G     +P +   +   G P P   P        P P
Sbjct: 1214 PPGIQGSPGKEGPPGPQGPSGLPG-----IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP 1268

Query: 257  CWGAGHSQTWRQGAGE--AQGTRGGS-ADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQC 313
              GA     ++   G+  A G RG S A G+P     Q    GK G     GP G     
Sbjct: 1269 -EGARGPPGFKGHTGDSGAPGPRGESGAMGLPG----QEGLPGKDGDTGPTGPQGPQGPR 1323

Query: 314  AMPGASGT-RSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSH 372
              PG +G+  SP       + G  GT   +G  G +    +PG  G   P    G  +  
Sbjct: 1324 GPPGKNGSPGSP------GEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGE-KGV 1376

Query: 373  PKGNCSPG--SSPGF-GELWPLGQQCPCVAQGPHGG-GKPSQALAAGPT--VSMCGMRPL 426
            P     PG    PGF GE    G +     +GP GG G+P      G      + G + L
Sbjct: 1377 PGKEGVPGKPGEPGFKGERGDPGIKGD---KGPPGGKGQPGDPGIPGHKGHTGLMGPQGL 1433

Query: 427  QGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQT 470
             G +  + P  PP           G   FP   G R  SPS++T
Sbjct: 1434 PGENGPVGPPGPP-----------GQPGFP---GLRGESPSMET 1463



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 97/389 (24%), Positives = 123/389 (31%), Gaps = 82/389 (21%)

Query: 134  LLAWQHPQKPPGGPQRPSPG---GLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGH 190
            LL  Q P  PPG P  P PG   GL G     G     GP G   K G     P  P G 
Sbjct: 709  LLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDG-----PNGPPGP 763

Query: 191  VACGAGIWTRAQAG-PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALS 249
                     R + G P K  +    G    +G                      RP    
Sbjct: 764  PGTKGEPGERGEDGLPGKPGLRGEIGEQGLAG----------------------RPGEKG 801

Query: 250  TAASPRPCWGAGHSQTWRQGAGEAQGTRGGSAD-------GIPELTCYQRSKCGKCGTVP 302
             A  P              GA    G RG   D       G+P L    R + G+ G   
Sbjct: 802  EAGLP--------------GAPGFPGVRGEKGDQGEKGELGLPGLK-GDRGEKGEAGPAG 846

Query: 303  TQGPPGT----NPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGG 358
              G PGT     P   MPG  G +           G+ G     G PG        G  G
Sbjct: 847  PPGLPGTTSLFTPHPRMPGEQGPK-----------GEKGDPGLPGEPGLQGRPGELGPQG 895

Query: 359  THSPIAARGRYRSH--PKGNCSPGSSPGFGELWPLGQQCPCVAQG----PHGGGKPSQAL 412
               P  A+G+  +H  P    +PG+    G   P G      A G    P   G+  +  
Sbjct: 896  PTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKG 955

Query: 413  AAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTN- 471
            AAG   S   + P        LP  PP     G+    GS   P   G +     ++ + 
Sbjct: 956  AAGEEGSPGPVGPRGDPGAPGLP-GPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE 1014

Query: 472  ----GGDGQRRSGGSWGETQSPEAGAQGN 496
                GG   +   G+ G   SP  G++G+
Sbjct: 1015 NCALGGQCVKGDRGAPGIPGSP--GSRGD 1041



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 73/276 (26%), Positives = 93/276 (33%), Gaps = 43/276 (15%)

Query: 154  GLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHKRAVGAA 213
            GL+G R   G +   GP G    + L   HP  P              + GP  +     
Sbjct: 831  GLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPG-------------EQGP--KGEKGD 875

Query: 214  AGAAQSSGLFSKWVPCQPLSQHPTGPEPSS-------RPHALSTAASPRPCWGAGHSQTW 266
             G     GL  +  P +   Q PTGP  +         P A     +P      G S   
Sbjct: 876  PGLPGEPGLQGR--PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGP- 932

Query: 267  RQGAGEAQGTRGGSA-DGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPI 325
              G+  A G RG    DG       +R + G  G   + GP G       PGA G   P 
Sbjct: 933  -PGSVGAPGLRGTPGKDG-------ERGEKGAAGEEGSPGPVGPRGD---PGAPGLPGPP 981

Query: 326  ATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAAR--GRYRSHPKGNCSPGS-- 381
               +  + G  G+    GP GT A C     G  +  +  +     R  P    SPGS  
Sbjct: 982  GKGKDGEPGLRGSPGLPGPLGTKAACGKV-RGSENCALGGQCVKGDRGAPGIPGSPGSRG 1040

Query: 382  SPGFGELWPLGQQCPCVAQG-PHGGGKPSQALAAGP 416
             PG G   P G   P   +G P   G P      GP
Sbjct: 1041 DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGP 1076



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 48/195 (24%), Positives = 63/195 (32%), Gaps = 34/195 (17%)

Query: 239 PEPSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKC 298
           P P     A+    +P P    G       G GE +G +G    G+P          G+ 
Sbjct: 495 PGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGE-KGEKGSL--GLP-------GPPGRD 544

Query: 299 GTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGG 358
           G+   +G PG   +  +PG  G R P                 QGPPG        GA G
Sbjct: 545 GSKGMRGEPGELGEPGLPGEVGMRGP-----------------QGPPGLPGPPGRVGAPG 587

Query: 359 THSPIAARGRYRSHPKGNCSPGSSPGF-GELWPLGQQCPCVAQGPHGG----GKPSQALA 413
                  +G      KG       PG  G+    G+  P    GP G     G       
Sbjct: 588 LQGERGEKG--TRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGV 645

Query: 414 AGPTVSMCGMRPLQG 428
            G  V   G++  QG
Sbjct: 646 PGSVVQQEGLKGEQG 660



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 17/47 (36%), Positives = 20/47 (42%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAG 189
            P G P RP  GGL GP    G    RG +G     G+     + P G
Sbjct: 1516 PMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPG 1562


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 73/297 (24%), Positives = 92/297 (30%), Gaps = 61/297 (20%)

Query: 140 PQKPPGGPQRPS-----------------PGGLRGPRSLSGSSPWRGPQGSLCKSGLCCA 182
           P  PPG P RP                  P G++GP  L G     G +G L   G    
Sbjct: 150 PPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPG---- 205

Query: 183 HPVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPS 242
           H  +P      GA         P  + +    G A                    GP+  
Sbjct: 206 HQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMA--------------------GPKGE 245

Query: 243 SRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVP 302
           + PH            G    +  R   G A G +G   +G P +    R   G  G   
Sbjct: 246 TGPHGYKGMVGAIGATGPPGEEGPRGPPGRA-GEKGD--EGSPGI----RGPQGITGPKG 298

Query: 303 TQGPPGTNPQCAMPGASGTRS-------PIATRRRSKCGKCGTVTAQGPPGTHAECAMPG 355
             GPPG N +   PG  G +        P +   +   G  G    +G PG   E    G
Sbjct: 299 ATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQG 358

Query: 356 AGGTHSPIAARGRYRSHPKGNCSP----GSSPGFGELWPLGQQCPCVAQGPHGGGKP 408
             G   P    G     P+G   P    G     GE  P+GQ  P   QGP G   P
Sbjct: 359 LPGFSGPPGKEGE--PGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGP 413



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 95/367 (25%), Positives = 115/367 (31%), Gaps = 53/367 (14%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P  PPG P  P   G+ G     G +   GP+G   K+G     P  P G          
Sbjct: 34  PPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAG-----PDGPDGKPGIDGLTGA 88

Query: 200 RAQAGPHK-RAVGAAAGAAQSSGLFSKWVPCQPLSQHPTG-------PEPSSRPHALSTA 251
           + + GP     V    G     GL        P    P G         P   P     +
Sbjct: 89  KGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPS 148

Query: 252 ASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNP 311
             P P    G         G  QG   GSAD +    C    K G  G    +G  G   
Sbjct: 149 GPPGPPGKPGR-------PGTIQGLE-GSADFLCPTNCPPGMK-GPPGLQGVKGHAGKRG 199

Query: 312 QCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRS 371
               PG  G   P     +   G  G     GPPG       PG  G             
Sbjct: 200 ILGDPGHQGKPGP-----KGDVGASGEQGIPGPPGPQGIRGYPGMAG------------- 241

Query: 372 HPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPLQGWSR 431
            PKG   P    G   +  +G   P   +GP   G P +A   G   S  G+R  QG + 
Sbjct: 242 -PKGETGPHGYKGM--VGAIGATGPPGEEGPR--GPPGRAGEKGDEGSP-GIRGPQGITG 295

Query: 432 SLLPKWPPATLWLGDDLFTGSCHFPSSFGQ--RCLSPSIQTNGG-DGQRRSGGSWGETQS 488
                 PP     G D   G+     S GQ  +  SP  Q   G  GQ  + G  G+   
Sbjct: 296 PKGATGPPGI--NGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGE 353

Query: 489 PEAGAQG 495
           P  G QG
Sbjct: 354 P--GPQG 358



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 65/256 (25%), Positives = 84/256 (32%), Gaps = 53/256 (20%)

Query: 140 PQKPPG-GPQRPSPG--GLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAG 196
           P+ PPG   ++   G  G+RGP+ ++G     GP G   K G     P  P    + G  
Sbjct: 269 PRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGT----PGTPGMKGSAG-- 322

Query: 197 IWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRP 256
                QAG          G+    GL    VP QP ++   G +    P  L   + P  
Sbjct: 323 -----QAGQ--------PGSPGHQGLAG--VPGQPGTKGGPGDQGEPGPQGLPGFSGPPG 367

Query: 257 CWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMP 316
             G    +   +G    QG  G   D        Q    G+ G    QGPPG      +P
Sbjct: 368 KEG----EPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLP 423

Query: 317 GASGTR-SPIATRRRSKCGKCGTVTAQGP------------------------PGTHAEC 351
           G  G + SP  T  R K G  G     G                         PG   + 
Sbjct: 424 GVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDA 483

Query: 352 AMPGAGGTHSPIAARG 367
             PG  G   P   RG
Sbjct: 484 GAPGVQGYPGPPGPRG 499


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 114/444 (25%), Positives = 145/444 (32%), Gaps = 69/444 (15%)

Query: 92  GPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRPS 151
           G G   A+GE   P  + +    E   G         P+G        P  PPG P  P 
Sbjct: 371 GAGEKGAKGE---PAVIEKGQQFEGPPGAPGPQGVVGPSG--------PPGPPGFPGDPG 419

Query: 152 PGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGI-WTRAQA-GPHKRA 209
           P G  G   + G    RGP G++         P + AG    G  + + +AQA    ++ 
Sbjct: 420 PPGPAGLPGIPGIDGIRGPPGTVIMM------PFQFAGGSFKGPPVSFQQAQAQAVLQQT 473

Query: 210 VGAAAGAAQSSGLFSK----WVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQT 265
             +  G     GL  +     +P  P  +   G E    P  L     P    G    + 
Sbjct: 474 QLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVG----KM 529

Query: 266 WRQGAGEAQGTRGGSA-------DGIPELT-----------CYQRSKCGKCGTVPTQGPP 307
            R GA  A+G  G +        DG+P L              Q    G+ G    +GPP
Sbjct: 530 GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPP 589

Query: 308 GTNPQCAMPGASG----TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPI 363
           G   Q   PG  G      SP  T R    G  G   A+G  G   E   PG  G H   
Sbjct: 590 GPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQ 649

Query: 364 AARGRY-------RSHPKGNCS-PGSSPGFGELWPLGQQCPC---VAQGPHGGGKPSQAL 412
              G            P GN   PG     G L   G + P     AQGP G   P    
Sbjct: 650 GLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYP 709

Query: 413 AAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNG 472
                    G R LQG          P   + GD    G    P + G R        +G
Sbjct: 710 GPRGVKGTSGNRGLQGEKGEKGEDGFPG--FKGDVGLKGDQGKPGAPGPR------GEDG 761

Query: 473 GDGQRRSGGSWGETQSP-EAGAQG 495
            +G +   G  GE   P  AG +G
Sbjct: 762 PEGPKGQAGQAGEEGPPGSAGEKG 785



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 76/303 (25%), Positives = 97/303 (32%), Gaps = 41/303 (13%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVR-PAGHVACGAGIW 198
            P  P G P    P G  G +   G+   +G +G    +G      +R PAGH        
Sbjct: 1059 PLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADG 1118

Query: 199  TRAQAGPH-------KRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTA 251
             + + GP           V    G     GL  + +P  P  +   G   S  PH     
Sbjct: 1119 AQGRRGPPGLFGQKGDDGVRGFVGVIGPPGL--QGLPGPPGEKGEVGDVGSMGPHGAPGP 1176

Query: 252  ASPRPCWGAGHSQTWRQGAGEA-----QGTRGGSAD-------GIPELTCYQRSKCGKCG 299
              P+   G+  +     G G+      +G RG + D       GIP        K G  G
Sbjct: 1177 RGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEK-GDSG 1235

Query: 300  TVPTQGPPGTNPQCAMPGASGTRSPIATR----------------RRSKCGKCGTVTAQG 343
                 GPPG        GA G+  P                       + G  G V   G
Sbjct: 1236 PSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPG 1295

Query: 344  PPGTHAECAMPGAGGTHSPIAARGRY-RSHPKG-NCSPGSSPGFGELWPLGQQCPCVAQG 401
            PPG   E   PG  G   P    GR  R   KG    PG     G   P+G + P    G
Sbjct: 1296 PPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVG 1355

Query: 402  PHG 404
            P G
Sbjct: 1356 PEG 1358



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 70/278 (25%), Positives = 94/278 (33%), Gaps = 48/278 (17%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
           PPG        GL GP+ L G+   +GP G+    GL  +    P GH         +  
Sbjct: 639 PPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDG--PLGHPGHEGPTGEKGA 696

Query: 203 AGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR-----PC 257
            GP       +AG     G              P G + +S    L      +     P 
Sbjct: 697 QGPP-----GSAGPPGYPG--------------PRGVKGTSGNRGLQGEKGEKGEDGFPG 737

Query: 258 WGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPG 317
           +         QG   A G RG      P+    Q  + G  G+   +G  G       PG
Sbjct: 738 FKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPG 797

Query: 318 ASGTRS---------PIATRRRS-KCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG 367
             G +          PI  + +S K G+ G    +GPPG+  E   PGA G         
Sbjct: 798 RPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATG--------- 848

Query: 368 RYRSHPKGNCSPGSSPGF-GELWPLGQQCPCVAQGPHG 404
             +  PKG+     +PG  GE    G Q P    GP G
Sbjct: 849 --QPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKG 884



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 75/282 (26%), Positives = 88/282 (31%), Gaps = 35/282 (12%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPV-RPAGHVACGAGIWTRA 201
            PPG P  P   GL G     G+    GP G L K G         P G          + 
Sbjct: 936  PPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKG 995

Query: 202  QAGPHKRAVGAAAGAAQSSGLFSK---WVPCQPLSQHPTGP--EPSSR-----PHALSTA 251
              GP    VGA     +   L       +P Q  S+ P GP  +  SR     P      
Sbjct: 996  DKGP-PGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKD 1054

Query: 252  ASPRPCWGAGHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTN 310
              P P    G       GA    G  G   D G P      +   G  G     G PG  
Sbjct: 1055 GIPGPLGPLG-----PPGAAGPSGEEGDKGDVGAPG----HKGSKGDKGDAGPPGQPGIR 1105

Query: 311  PQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYR 370
                 PG  G     A  RR   G  G     G  G       PG  G   P   +G   
Sbjct: 1106 GPAGHPGPPGADG--AQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVG 1163

Query: 371  SHPKGNCSPGSSPGFGELWPLGQQCPCVAQG----PHGGGKP 408
                G+  P  +PG     P G Q P  ++G    P G G+P
Sbjct: 1164 D--VGSMGPHGAPG-----PRGPQGPTGSEGTPGLPGGVGQP 1198



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 81/322 (25%), Positives = 103/322 (31%), Gaps = 76/322 (23%)

Query: 91   GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRP 150
            G PG     GE   P   GR+ G +  +G    L    PAG           P GGP  P
Sbjct: 935  GPPGPPGPPGEQGLPGLEGRE-GAKGELGPPGPLGKEGPAGLRGFPG-----PKGGPGDP 988

Query: 151  SPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHKRAV 210
             P GL+G +   G     G  GS  + G     P+ PAG +       +    GP     
Sbjct: 989  GPTGLKGDKGPPGPV---GANGSPGERG-----PLGPAGGIGLPGQSGSEGPVGP----- 1035

Query: 211  GAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSR-PHALSTAASPRPCWGAGHS-QTWRQ 268
               AG   S G            + P GP      P  L     P     +G        
Sbjct: 1036 ---AGKKGSRG-----------ERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDV 1081

Query: 269  GAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIAT- 327
            GA   +G++G   D  P        + G  G     GPPG +      GA G R P    
Sbjct: 1082 GAPGHKGSKGDKGDAGPP------GQPGIRGPAGHPGPPGAD------GAQGRRGPPGLF 1129

Query: 328  RRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGFGE 387
             ++   G  G V   GPPG      +PG  G                           GE
Sbjct: 1130 GQKGDDGVRGFVGVIGPPGLQG---LPGPPGEK-------------------------GE 1161

Query: 388  LWPLGQQCPCVAQGPHGGGKPS 409
            +  +G   P  A GP G   P+
Sbjct: 1162 VGDVGSMGPHGAPGPRGPQGPT 1183



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 73/286 (25%), Positives = 89/286 (31%), Gaps = 54/286 (18%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            PPG P  P P G  G +  SG S   GP G   K G        P G       +     
Sbjct: 1215 PPGAPGIPGPKGDIGEKGDSGPSGAAGPPG---KKG--------PPGEDGAKGSVGPTGL 1263

Query: 203  AG----PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCW 258
             G    P    V    G+    G         P      GP     P A     +P P  
Sbjct: 1264 PGDLGPPGDPGVSGIDGSPGEKG--------DPGDVGGPGP-----PGASGEPGAPGPPG 1310

Query: 259  GAGHS-QTWRQGAGEAQGTRGGSA-DGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMP 316
              G S    R+G    +G +G    DG P          G+ G +  +GPPG   +    
Sbjct: 1311 KRGPSGHMGREGREGEKGAKGEPGPDGPP----------GRTGPMGARGPPG---RVGPE 1357

Query: 317  GASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY----RSH 372
            G  G   P+      + G  G     GPPG      +PG  G   P   +G         
Sbjct: 1358 GLRGIPGPVG-----EPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIG 1412

Query: 373  PKGNCSPGSSPGF-GELWPLGQQCPCVAQGPHGG-GKPSQALAAGP 416
            P G        G  G   P G +      GP G  G P     AGP
Sbjct: 1413 PPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGP 1458



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 72/293 (24%), Positives = 100/293 (34%), Gaps = 40/293 (13%)

Query: 141  QKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCA-----HPVRPAGHVACGA 195
            Q  PG P      G  GP+  +G +   GP GS  + G         +P RP    + G 
Sbjct: 748  QGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGF 807

Query: 196  GIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR 255
                    GP    +G    + ++          QP  +   GP P SR       A+ +
Sbjct: 808  P----GPLGP----IGEKGKSGKTG---------QPGLEGERGP-PGSRGERGQPGATGQ 849

Query: 256  PCWGAGHSQTWRQGA-GEA--QGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQ 312
            P       Q    G  GE    G +G      P+     + K G+ G    +G  G   Q
Sbjct: 850  PGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQ 909

Query: 313  CAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY--- 369
               PG +G   P     + K G+ G +  +GPPG        G  G      A+G     
Sbjct: 910  TGPPGPAGVLGP-----QGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPP 964

Query: 370  ----RSHPKG-NCSPGSSPGFGELWPLGQQCPCVAQGPHG-GGKPSQALAAGP 416
                +  P G    PG   G G+  P G +      GP G  G P +    GP
Sbjct: 965  GPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGP 1017



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 67/260 (25%), Positives = 81/260 (31%), Gaps = 60/260 (23%)

Query: 91   GGPGNWRAEGETEAPLTVGRDSGLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRP 150
            GGPG   A GE  AP   G+  G    +G     R  +           P  PPG   R 
Sbjct: 1292 GGPGPPGASGEPGAPGPPGK-RGPSGHMG-----REGREGEKGAKGEPGPDGPPG---RT 1342

Query: 151  SPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAGPHKRAV 210
             P G RGP    G    RG  G + + GL                 +    Q GP     
Sbjct: 1343 GPMGARGPPGRVGPEGLRGIPGPVGEPGL-----------------LGAPGQMGP----- 1380

Query: 211  GAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQGA 270
                G    SGL        P  +  TGP+       L     P    G    +   QG 
Sbjct: 1381 ---PGPLGPSGL--------PGLKGDTGPKGEKGHIGLIGLIGPPGEAG----EKGDQGL 1425

Query: 271  GEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRR 330
               QG  G   D  P          G  G++   GPPG        G+ G+   +  R  
Sbjct: 1426 PGVQGPPGPKGDPGPP---------GPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPR-- 1474

Query: 331  SKCGKCGTVTAQGPPGTHAE 350
               G  G     GPPG  AE
Sbjct: 1475 ---GDTGPAGPPGPPGAPAE 1491


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 88/336 (26%), Positives = 115/336 (34%), Gaps = 33/336 (9%)

Query: 123  GLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRG-----PQGSLCKS 177
            GL T  P G        P  P GG   P P G     + +  SP  G     P+G+    
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198

Query: 178  GLCCAHPVRPAGHVACGA--GIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQH 235
                A P  P G +A  +  G  T   A P     G A  + + +       P  P    
Sbjct: 1199 A---ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG- 1254

Query: 236  PTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQ-----GTRGGSADGIPE---- 286
            P  P P   P     AA+P P    G +    +GA           +GG A   P+    
Sbjct: 1255 PATPPPKGAP--TPPAATP-PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311

Query: 287  -LTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPP 345
                   S  G  GT P +G P T P    P   GT +  AT   SK G     + +GP 
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAP-TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT 1370

Query: 346  GTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHGG 405
               A  +  G      P   RG     PKG+    +SP    L P  ++ P       G 
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGD---PTSPAVIPLSP--KKAPATPVTREGA 1425

Query: 406  GKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPAT 441
              PS+     P V+   ++     S    PK  PAT
Sbjct: 1426 ATPSKGDLTPPAVTPVSLKKAPATS---APKGGPAT 1458



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 80/325 (24%), Positives = 103/325 (31%), Gaps = 34/325 (10%)

Query: 123  GLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC-- 180
            G  T  P G        P  P GGP  PSP G   P +++  SP   P  +    G    
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035

Query: 181  -CAHPVRPAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPT-- 237
              A P  P G  A    +   A   P         G A  S    K  P  P +  P+  
Sbjct: 1036 PAATPPSPKGSPA-ATPLPKGAPTTPAATLPSPKGGPATPS---LKGAPTPPAATPPSPK 1091

Query: 238  -GP-EPSSRPHALSTAASPRPCWGA----GHSQTWRQGAGEAQGTRGGSADGIPE----- 286
             GP  PS +   +  AA+P    G      H       A      +GG A   P+     
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151

Query: 287  LTCYQRSKCGKCGTVPTQG--------PPGTNPQCAMPGASGTRSPIATRRRSKCGKCGT 338
                  S  G   T P +G        PP      A P   G  +  A    S  G   T
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1211

Query: 339  VTAQGPPGTHAECAMPGAGGTHSPI---AARGRYRSHPKGNCSPGSSPGFGELWPLGQQC 395
             + +G P T A       GG  +P    A      + P     P + P  G   P     
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271

Query: 396  PCVAQG---PHGGGKPSQALAAGPT 417
            P +  G   P   G P+ A+   P+
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPS 1296



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 71/309 (22%), Positives = 96/309 (31%), Gaps = 42/309 (13%)

Query: 140  PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
            P  P GGP  PSP G   P + +  SP  GP     K          P+   +  A  + 
Sbjct: 970  PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP 1029

Query: 200  RAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWG 259
            +  + P      +  G+  ++ L  K  P  P +   T P P   P   S   +P P   
Sbjct: 1030 KGASTPPAATPPSPKGSPAATPL-PKGAPTTPAA---TLPSPKGGPATPSLKGAPTP--- 1082

Query: 260  AGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGAS 319
                      A      +GG A   P+               P   PP      A P   
Sbjct: 1083 ---------PAATPPSPKGGPATPSPK----------GAPMPPAATPPSPKGGLATPPHK 1123

Query: 320  GTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKG-NCS 378
            G  +  A    S  G   T   +G P T A       GG  +P          PKG   +
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP---------PPKGAPTT 1174

Query: 379  PGSSP-----GFGELWPLGQQCPCVAQGPH-GGGKPSQALAAGPTVSMCGMRPLQGWSRS 432
            P ++P     G     P G      A  P   GG  + +    PT         +G   +
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234

Query: 433  LLPKWPPAT 441
              PK  P T
Sbjct: 1235 PSPKGAPTT 1243



 Score = 36.6 bits (83), Expect = 0.088
 Identities = 75/310 (24%), Positives = 97/310 (31%), Gaps = 27/310 (8%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLC--CAHPVRPAGHVACGA--GIW 198
            P G P  PSP G   P + +  SP  GP     K       A P  P G  A  +  G  
Sbjct: 927  PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986

Query: 199  TRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCW 258
            T   A P     G A  + + +       P  P       P P     +   AA+P    
Sbjct: 987  TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGA--STPPAATPPSPK 1044

Query: 259  GAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGA 318
            G+  +    +GA         S  G P     + +      T P   PP      A P  
Sbjct: 1045 GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP-----TPPAATPPSPKGGPATPSP 1099

Query: 319  SGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKG-NC 377
             G   P A    S  G   T   +G P T A       GG  +P          PKG   
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP---------PPKGAPT 1150

Query: 378  SPGSSP-----GFGELWPLGQQCPCVAQGPH-GGGKPSQALAAGPTVSMCGMRPLQGWSR 431
            +P ++P     G     P G      A  P   GG  + +    PT         +G   
Sbjct: 1151 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1210

Query: 432  SLLPKWPPAT 441
            +  PK  P T
Sbjct: 1211 TPSPKGAPTT 1220


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 100/381 (26%), Positives = 123/381 (32%), Gaps = 55/381 (14%)

Query: 145 GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAH----PVRPAGHVACGAGIWTR 200
           G P R    GL GP+   GS   +G +G     G   +     P  P G+   G  I  +
Sbjct: 559 GSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGP-IGDK 617

Query: 201 AQAGPHKRAVGAAAGAAQSSGLFSKWVP------CQPLSQHPTGPEPSSRPHALSTAASP 254
            QAG        + G     G   K VP       + L   P  P P        T    
Sbjct: 618 GQAG--FPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPG-- 673

Query: 255 RPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCA 314
           RP          + G G          DG+P          G  G   T G PG N    
Sbjct: 674 RPGLPGEKGAVGQPGIGFPGPPGPKGVDGLP----------GDMGPPGTPGRPGFNGLPG 723

Query: 315 MPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG--RYRSH 372
            PG  G +           G  G     G PG      +PG  G H  I   G    R  
Sbjct: 724 NPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGE 783

Query: 373 PKGNCSPGS--SPGFGELWPLGQQCPCVAQGPHG-----GGKPSQALAAGPTVSMCGMRP 425
           P     PGS  SPG   + P G + P   QGP G     G K  +     P + M G + 
Sbjct: 784 PGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKG 843

Query: 426 LQG-------WSRSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRR 478
            +G         +S LP  P      G     G   FP S G+      +   G  GQ  
Sbjct: 844 DKGAQGLPGITGQSGLPGLP------GQQGAPGIPGFPGSKGE------MGVMGTPGQPG 891

Query: 479 SGGSWGETQSPEAGAQGNHVF 499
           S G  G    P  G +G+H F
Sbjct: 892 SPGPVGAPGLP--GEKGDHGF 910



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 73/269 (27%), Positives = 88/269 (32%), Gaps = 27/269 (10%)

Query: 143 PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGL--CCAHPVRPAGHVACGAGIWTR 200
           PPG P  P   G +G R   G     G  G+    GL      P    GHV    G+  +
Sbjct: 116 PPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVP---GMLLK 172

Query: 201 AQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGA 260
            + G          G     GL        P  Q P GP   + P        P P    
Sbjct: 173 GERG-----FPGIPGTPGPPGL--------PGLQGPVGPPGFTGPPG--PPGPPGPPGEK 217

Query: 261 GHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGAS 319
           G      QG    +G +G S   G+P     Q    G   T   +G  G      MPG  
Sbjct: 218 GQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEK--GDFATKGEKGQKGEPGFQGMPGVG 275

Query: 320 GTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSP 379
               P     R K GK G    +G PG   E   PG  G   P   +G   + P G   P
Sbjct: 276 EKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKG--EAGPPG--PP 331

Query: 380 GSSPGFGELWPLGQQCPCVAQGPHGGGKP 408
           G   G G L   G++      GP G   P
Sbjct: 332 GIVIGTGPLGEKGERGYPGTPGPRGEPGP 360



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 74/310 (23%), Positives = 100/310 (32%), Gaps = 47/310 (15%)

Query: 144  PGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQA 203
            PG P  P P G  G   L G+   +G  G     G     P  P    A G     + QA
Sbjct: 1001 PGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQG----SPGLPGDKGAKG----EKGQA 1052

Query: 204  GPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASP-RPCWGAGH 262
            GP    +    G     G          ++  P  P       ++     P  P      
Sbjct: 1053 GPPGIGIPGLRGEKGDQG----------IAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSP 1102

Query: 263  SQTWRQGAGEAQGTRGGSA----DGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGA 318
                  G+    G +G       DGIP +        G+ G   T GP G   Q   PG+
Sbjct: 1103 GSVGYPGSPGLPGEKGDKGLPGLDGIPGVK-------GEAGLPGTPGPTGPAGQKGEPGS 1155

Query: 319  SGTRSPIATRRRSKC---GKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGR--YRSHP 373
             G       +        G  G   A+G  G+  E   PG  G+     ++G   +   P
Sbjct: 1156 DGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPP 1215

Query: 374  KGNCSPG--SSPGFGELWPLGQQCPCVAQGPHG-GGKPSQALAAGPTVSMCGMRPLQGWS 430
                 PG   SPG     P G       +GP G  G P      GP   + G+  ++G  
Sbjct: 1216 GPQGQPGLPGSPGHATEGPKGD------RGPQGQPGLPGLPGPMGPP-GLPGIDGVKGDK 1268

Query: 431  RSLLPKWPPA 440
             +  P WP A
Sbjct: 1269 GN--PGWPGA 1276



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 90/382 (23%), Positives = 125/382 (32%), Gaps = 37/382 (9%)

Query: 138 QHPQKPPGGPQRPSPGGLRGPRSLSGSS--PWRGPQGSLCKSGLCCAHPVRPAGHVACGA 195
           Q P  PPG    P P G  GP    G     ++GP+G     G+     V     V    
Sbjct: 193 QGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKG 252

Query: 196 GIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR 255
              T+ + G          G     G+  K  P +P  +   G +   +    S      
Sbjct: 253 DFATKGEKGQK-----GEPGFQGMPGVGEKGEPGKPGPRGKPGKD-GDKGEKGSPGFPGE 306

Query: 256 PCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAM 315
           P +     +   QG     G  G     I      ++ + G  GT   +G PG      +
Sbjct: 307 PGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGL 366

Query: 316 PGASGTRS-PIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPK 374
           PG  G    P+           G   A G PG   E    G  GT  P  +       P 
Sbjct: 367 PGQPGPPGLPVP----------GQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPP 416

Query: 375 GNCSPGSSPGFGELWPLGQQCPCVAQGPHG-GGKP---SQALAAGPTVSMCGMRPLQGWS 430
           G+  P   PG+       Q  P   QGP G  G+P    +    G     C +  + G+ 
Sbjct: 417 GSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYR 476

Query: 431 RSLLPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQRRSGGSWGETQSPE 490
               P+ PP     G+  F G    P + G R L       G  G + + G  G     +
Sbjct: 477 GPPGPQGPP-----GEIGFPGQ---PGAKGDRGLPGRDGVAGVPGPQGTPGLIG-----Q 523

Query: 491 AGAQGN-HVFCVDFAISGGKED 511
            GA+G    F  D  + G K D
Sbjct: 524 PGAKGEPGEFYFDLRLKGDKGD 545



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 49/182 (26%), Positives = 62/182 (34%), Gaps = 27/182 (14%)

Query: 249 STAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPG 308
           S AA+   C G+G  +    G    +G RG    G+  +  +     G  G    QGPPG
Sbjct: 23  SRAAAKGGCAGSGCGKCDCHGVKGQKGERG--LPGLQGVIGFP----GMQGPEGPQGPPG 76

Query: 309 TNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARG- 367
                  PG  GT+           G  G   A G PG      +PG  G   P    G 
Sbjct: 77  QKGDTGEPGLPGTK-----------GTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGC 125

Query: 368 RYRSHPKGNCSPGSSPGF-GELWPLGQQCPCVAQGPHGGGKPSQALAAGPTVSMCGMRPL 426
                 +G   P   PGF G   P G         P   G P + L   P + + G R  
Sbjct: 126 NGTKGERGPLGPPGLPGFAGNPGPPGL--------PGMKGDPGEILGHVPGMLLKGERGF 177

Query: 427 QG 428
            G
Sbjct: 178 PG 179



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 96/378 (25%), Positives = 125/378 (33%), Gaps = 39/378 (10%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            PPG   R  PGG +GP  LSG    +G +G     GL    P    G             
Sbjct: 803  PPGA--RGPPGG-QGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGL 859

Query: 203  AG-PHKRAVGAAAGAAQSSGLFSKW-VPCQPLSQHPTGPE--PSSR-PHALSTAASPRPC 257
             G P ++      G   S G       P QP S  P G    P  +  H    ++ PR  
Sbjct: 860  PGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGD 919

Query: 258  WGA-------------GHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQ 304
             G              G       G+ + Q    G    I  +      + G  G   T 
Sbjct: 920  PGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPI-----GEKGSRGDPGTP 974

Query: 305  GPPGTNPQCAMPGASGTRSPIATRRRSKC----GKCGTVTAQGPPGTHAECAMPGAGGTH 360
            G PG + Q   PG  G +               G  G+V   G PGT  E  +PG  G  
Sbjct: 975  GVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQ 1034

Query: 361  -SPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQ-CPCVAQGPHGGGKPSQALAAGPTV 418
             SP     +     KG   P   PG G     G++    +A  P   G+  +  + G   
Sbjct: 1035 GSPGLPGDKGAKGEKGQAGP---PGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIG-IP 1090

Query: 419  SMCGMRPLQGWSRSL-LPKWPPATLWLGDDLFTGSCHFPSSFGQRCLSPSIQTNGGDGQR 477
             M G   L+G   S+  P  P      GD    G    P   G+  L  +    G  GQ+
Sbjct: 1091 GMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQK 1150

Query: 478  RSGGSWGETQSPEAGAQG 495
               GS G   S  AG +G
Sbjct: 1151 GEPGSDGIPGS--AGEKG 1166



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 74/288 (25%), Positives = 100/288 (34%), Gaps = 39/288 (13%)

Query: 141  QKPPGGPQRPSPGGLRGPRS------LSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACG 194
            +K   GP      GLRG +         GS   +G +GS+   G+    P  P    + G
Sbjct: 1048 EKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGM----PGSPGLKGSPG 1103

Query: 195  AGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGP-----EPSSRPHALS 249
            +  +  +   P ++      G     G+  K     P +  PTGP     EP S     S
Sbjct: 1104 SVGYPGSPGLPGEKGDKGLPGLDGIPGV--KGEAGLPGTPGPTGPAGQKGEPGSDGIPGS 1161

Query: 250  TAASPRPCWGAGHSQTWRQGAGEAQGTRGGSAD-GIPELTCYQRSKCGKCGTVPTQGPPG 308
                  P    G       G   A+G +G   + G P L        G  G     GPPG
Sbjct: 1162 AGEKGEP----GLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIP-GSKGEQGFMGPPG 1216

Query: 309  TNPQCAMPGASG--TRSPIATR-RRSKCGKCGTVTAQGPP---------GTHAECAMPGA 356
               Q  +PG+ G  T  P   R  + + G  G     GPP         G       PGA
Sbjct: 1217 PQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGA 1276

Query: 357  GGTHSPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG 404
             G   P    G ++  P    SPG +   G++ P G       QGP G
Sbjct: 1277 PGVPGPKGDPG-FQGMPGIGGSPGITGSKGDMGPPGVP---GFQGPKG 1320



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 80/318 (25%), Positives = 106/318 (33%), Gaps = 60/318 (18%)

Query: 91  GGPGNWRAEGETEAPLTVGRDS--GLEAGVGV-GCGLRTAQ-PAGFELLAWQHPQKPPGG 146
           G PG    +G+   P T GR    G +  VG  G G      P G + L       PPG 
Sbjct: 655 GSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGD--MGPPGT 712

Query: 147 PQRP-------SPG-------------GLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVR 186
           P RP       +PG             GL+G   L G     G +GS+   G+       
Sbjct: 713 PGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGV------- 765

Query: 187 PAGHVACGAGIWTRAQAGPHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPH 246
           P  H A G       +  P    +  + G+    G+        P  Q P  P  S  P 
Sbjct: 766 PGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGP--PGLSGPPG 823

Query: 247 ALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGP 306
                  P      G       G    +G +G  A G+P +T     + G  G    QG 
Sbjct: 824 IKGEKGFP------GFPGLDMPG---PKGDKG--AQGLPGIT----GQSGLPGLPGQQGA 868

Query: 307 PGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAAR 366
           PG       PG+ G    + T    + G  G V A G PG   +   PG+ G       +
Sbjct: 869 PGIP---GFPGSKGEMGVMGT--PGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLK 923

Query: 367 GRYRSHPKGNCSPGSSPG 384
           G      KG+      PG
Sbjct: 924 G-----DKGDVGLPGKPG 936



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 67/257 (26%), Positives = 83/257 (32%), Gaps = 39/257 (15%)

Query: 143  PPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQ 202
            PPG   +P   G  G  +  G    RGPQG     GL    P+ P G          +  
Sbjct: 1214 PPGPQGQPGLPGSPG-HATEGPKGDRGPQGQPGLPGL--PGPMGPPGLPGIDGVKGDKGN 1270

Query: 203  AG-PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAG 261
             G P    V    G     G+     P    S   TG +    P  +     P+   G  
Sbjct: 1271 PGWPGAPGVPGPKGDPGFQGM-----PGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGL- 1324

Query: 262  HSQTWRQGAGEAQGTRG-GSADGIPELTC----YQRSKCGKCGTVPTQGPPGTNPQCAMP 316
                  QG    QG +G   A G+P        Y   K G+ G    +GPPG      +P
Sbjct: 1325 ------QGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIK-GEPGLPGPEGPPGLKGLQGLP 1377

Query: 317  GASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGN 376
            G  G +           G  G V   GPPG       PG  G   P    G     P+G 
Sbjct: 1378 GPKGQQ-----------GVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTG-----PRGF 1421

Query: 377  CSPGSSPGF-GELWPLG 392
              P    G  G + P G
Sbjct: 1422 PGPPGPDGLPGSMGPPG 1438


>gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens]
          Length = 717

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 65/253 (25%), Positives = 84/253 (33%), Gaps = 38/253 (15%)

Query: 145 GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG 204
           G P  P   G +GPR   G     GPQG   K G        P G         +  + G
Sbjct: 488 GLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDG--------PPGVKGENGHPGSPGEKG 539

Query: 205 PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQ 264
             K   G A    +      K  P   +   P GPE    P  L     P+        +
Sbjct: 540 -EKGETGQAGSPGEKGEAGEKGNPGAEVPGLP-GPEGPPGPPGLQGVPGPK-------GE 590

Query: 265 TWRQGAGEAQGTRGGSAD----GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
               GA   +G +G   D    G+P          G  G     GPPGT     +PG +G
Sbjct: 591 AGLDGAKGEKGFQGEKGDRGPLGLP----------GASGLDGRPGPPGTPGPIGVPGPAG 640

Query: 321 TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPG 380
            +    +  +   G  G   A G PG H      G  G      +RG     PKG+    
Sbjct: 641 PKGERGS--KGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRG-----PKGDKGDQ 693

Query: 381 SSPGFGELWPLGQ 393
            +PG     PLG+
Sbjct: 694 GAPGLDAPCPLGE 706



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 74/305 (24%), Positives = 103/305 (33%), Gaps = 51/305 (16%)

Query: 113 GLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQG 172
           G +  +G+   + +   AG  ++    P+ PPG P      G  GP  L G     GP+G
Sbjct: 134 GDKGAIGMPGRVGSPGDAGLSIIG---PRGPPGQPGTRGFPGFPGPIGLDGKPGHPGPKG 190

Query: 173 SLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG--PHKRAVGAAAGAAQSSGLFS-KWVPC 229
            +  +G        P G          + Q G  PH+  + +   A +SS + + K +P 
Sbjct: 191 DMGLTG--------PPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLLPL 242

Query: 230 QPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSAD-GIPELT 288
             L+     P P  +          R  +    SQ   QG     G  G S   G P L 
Sbjct: 243 --LNSVRLAPPPVIK----------RRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLP 290

Query: 289 CYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRS----PIATRRRSKCGKCGTVTA--- 341
                  G  G     GPPG      + G  G +     P    +    G  G   A   
Sbjct: 291 -------GPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMK 343

Query: 342 --QGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSPGFGELWPLGQQCPCVA 399
              G PGT  E    G+ G    +  +G      KG+       G GE  P G   P   
Sbjct: 344 GEPGIPGTKGEKGAEGSPGLPGLLGQKGE-----KGDAGNSIGGGRGEPGPPGLPGP--- 395

Query: 400 QGPHG 404
            GP G
Sbjct: 396 PGPKG 400



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 67/289 (23%), Positives = 88/289 (30%), Gaps = 47/289 (16%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P  PPG P  P P G  G +   G    RG  G   K G   A  +  AG         T
Sbjct: 292 PMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGT 351

Query: 200 RAQAG-------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
           + + G       P         G A +S    +  P  P    P GP+  +         
Sbjct: 352 KGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG-QVGP 410

Query: 253 SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQ---RSKCGKCGTVPTQGPPGT 309
             +P           QG    +G++G    G  E+  Y         +  T+   GPPG 
Sbjct: 411 PGQPGDKGERGAAGEQGPDGPKGSKGEPGKG--EMVDYNGNINEALQEIRTLALMGPPGL 468

Query: 310 NPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY 369
             Q   PGA G                        PG   E  +PG  G       RG+ 
Sbjct: 469 PGQIGPPGAPGI-----------------------PGQKGEIGLPGPPGHDGEKGPRGK- 504

Query: 370 RSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG-GGKPSQALAAGPT 417
                    PG     G   P G+  P   +G +G  G P +    G T
Sbjct: 505 ---------PGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGET 544


>gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens]
          Length = 655

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 65/253 (25%), Positives = 84/253 (33%), Gaps = 38/253 (15%)

Query: 145 GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG 204
           G P  P   G +GPR   G     GPQG   K G        P G         +  + G
Sbjct: 426 GLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDG--------PPGVKGENGHPGSPGEKG 477

Query: 205 PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQ 264
             K   G A    +      K  P   +   P GPE    P  L     P+        +
Sbjct: 478 -EKGETGQAGSPGEKGEAGEKGNPGAEVPGLP-GPEGPPGPPGLQGVPGPK-------GE 528

Query: 265 TWRQGAGEAQGTRGGSAD----GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
               GA   +G +G   D    G+P          G  G     GPPGT     +PG +G
Sbjct: 529 AGLDGAKGEKGFQGEKGDRGPLGLP----------GASGLDGRPGPPGTPGPIGVPGPAG 578

Query: 321 TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPG 380
            +    +  +   G  G   A G PG H      G  G      +RG     PKG+    
Sbjct: 579 PKGERGS--KGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRG-----PKGDKGDQ 631

Query: 381 SSPGFGELWPLGQ 393
            +PG     PLG+
Sbjct: 632 GAPGLDAPCPLGE 644



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 68/262 (25%), Positives = 85/262 (32%), Gaps = 30/262 (11%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P+ PPG P      G  GP  L G     GP+G +  +G        P G          
Sbjct: 137 PRGPPGQPGTRGFPGFPGPIGLDGKPGHPGPKGDMGLTG--------PPGQPGPQGQKGE 188

Query: 200 RAQAG--PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR-- 255
           + Q G  PH R   + A      G      P  PL  HP  P P   P  L     P+  
Sbjct: 189 KGQCGEYPH-RGEQSQASIQGPPGPPGPPGPSGPLG-HPGLPGPMG-PPGLPGPPGPKGD 245

Query: 256 PCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAM 315
           P     H +   +G     G  G  A G P +        G+ G   T+G  G      +
Sbjct: 246 PGIQGYHGRKGERGMPGMPGKHG--AKGAPGIAV--AGMKGEPGIPGTKGEKGAEGSPGL 301

Query: 316 PGASGTRSPIATRRRS---KCGKCGTVTAQGPPGTHAECAM------PGAGGTHSPIAAR 366
           PG  G +        S     G+ G     GPPG   E  +      PG  G      A 
Sbjct: 302 PGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAA 361

Query: 367 GRYRSHPKGNCSPGSSPGFGEL 388
           G     P G       PG GE+
Sbjct: 362 G--EQGPDGPKGSKGEPGKGEM 381



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 75/294 (25%), Positives = 93/294 (31%), Gaps = 54/294 (18%)

Query: 138 QHPQKPPG--GPQRP----------SPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPV 185
           Q P  PPG  GP  P           P GL GP    G    +G  G   + G+    P 
Sbjct: 207 QGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGM----PG 262

Query: 186 RPAGHVACGA-GIWTRAQAG----PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE 240
            P  H A GA GI      G    P  +    A G+    GL  +            G  
Sbjct: 263 MPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGR 322

Query: 241 PSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGK--- 297
               P  L     P+   G    Q    G    +G RG + +  P+     + + GK   
Sbjct: 323 GEPGPPGLPGPPGPKGEAGV-DGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEM 381

Query: 298 -------------CGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGP 344
                          T+   GPPG   Q   PGA G             G+ G +   GP
Sbjct: 382 VDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIP-----------GQKGEIGLPGP 430

Query: 345 PGTHAECAMPGAGGTHSPIAARG-RYRSHPKG----NCSPGSSPGFGELWPLGQ 393
           PG   E    G  G   P   +G   +  P G    N  PGS    GE    GQ
Sbjct: 431 PGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQ 484



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 67/289 (23%), Positives = 88/289 (30%), Gaps = 47/289 (16%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P  PPG P  P P G  G +   G    RG  G   K G   A  +  AG         T
Sbjct: 230 PMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGT 289

Query: 200 RAQAG-------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
           + + G       P         G A +S    +  P  P    P GP+  +         
Sbjct: 290 KGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG-QVGP 348

Query: 253 SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQ---RSKCGKCGTVPTQGPPGT 309
             +P           QG    +G++G    G  E+  Y         +  T+   GPPG 
Sbjct: 349 PGQPGDKGERGAAGEQGPDGPKGSKGEPGKG--EMVDYNGNINEALQEIRTLALMGPPGL 406

Query: 310 NPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY 369
             Q   PGA G                        PG   E  +PG  G       RG+ 
Sbjct: 407 PGQIGPPGAPGI-----------------------PGQKGEIGLPGPPGHDGEKGPRGK- 442

Query: 370 RSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG-GGKPSQALAAGPT 417
                    PG     G   P G+  P   +G +G  G P +    G T
Sbjct: 443 ---------PGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGET 482


>gi|22027599 alpha 1 type XIII collagen isoform 14 [Homo sapiens]
          Length = 664

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 65/253 (25%), Positives = 84/253 (33%), Gaps = 38/253 (15%)

Query: 145 GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG 204
           G P  P   G +GPR   G     GPQG   K G        P G         +  + G
Sbjct: 435 GLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDG--------PPGVKGENGHPGSPGEKG 486

Query: 205 PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQ 264
             K   G A    +      K  P   +   P GPE    P  L     P+        +
Sbjct: 487 -EKGETGQAGSPGEKGEAGEKGNPGAEVPGLP-GPEGPPGPPGLQGVPGPK-------GE 537

Query: 265 TWRQGAGEAQGTRGGSAD----GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
               GA   +G +G   D    G+P          G  G     GPPGT     +PG +G
Sbjct: 538 AGLDGAKGEKGFQGEKGDRGPLGLP----------GASGLDGRPGPPGTPGPIGVPGPAG 587

Query: 321 TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPG 380
            +    +  +   G  G   A G PG H      G  G      +RG     PKG+    
Sbjct: 588 PKGERGS--KGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRG-----PKGDKGDQ 640

Query: 381 SSPGFGELWPLGQ 393
            +PG     PLG+
Sbjct: 641 GAPGLDAPCPLGE 653



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 68/262 (25%), Positives = 85/262 (32%), Gaps = 30/262 (11%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P+ PPG P      G  GP  L G     GP+G +  +G        P G          
Sbjct: 146 PRGPPGQPGTRGFPGFPGPIGLDGKPGHPGPKGDMGLTG--------PPGQPGPQGQKGE 197

Query: 200 RAQAG--PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPR-- 255
           + Q G  PH R   + A      G      P  PL  HP  P P   P  L     P+  
Sbjct: 198 KGQCGEYPH-RGEQSQASIQGPPGPPGPPGPSGPLG-HPGLPGPMG-PPGLPGPPGPKGD 254

Query: 256 PCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAM 315
           P     H +   +G     G  G  A G P +        G+ G   T+G  G      +
Sbjct: 255 PGIQGYHGRKGERGMPGMPGKHG--AKGAPGIAV--AGMKGEPGIPGTKGEKGAEGSPGL 310

Query: 316 PGASGTRSPIATRRRS---KCGKCGTVTAQGPPGTHAECAM------PGAGGTHSPIAAR 366
           PG  G +        S     G+ G     GPPG   E  +      PG  G      A 
Sbjct: 311 PGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAA 370

Query: 367 GRYRSHPKGNCSPGSSPGFGEL 388
           G     P G       PG GE+
Sbjct: 371 G--EQGPDGPKGSKGEPGKGEM 390



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 75/294 (25%), Positives = 93/294 (31%), Gaps = 54/294 (18%)

Query: 138 QHPQKPPG--GPQRP----------SPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPV 185
           Q P  PPG  GP  P           P GL GP    G    +G  G   + G+    P 
Sbjct: 216 QGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGM----PG 271

Query: 186 RPAGHVACGA-GIWTRAQAG----PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPE 240
            P  H A GA GI      G    P  +    A G+    GL  +            G  
Sbjct: 272 MPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGR 331

Query: 241 PSSRPHALSTAASPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQRSKCGK--- 297
               P  L     P+   G    Q    G    +G RG + +  P+     + + GK   
Sbjct: 332 GEPGPPGLPGPPGPKGEAGV-DGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEM 390

Query: 298 -------------CGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGP 344
                          T+   GPPG   Q   PGA G             G+ G +   GP
Sbjct: 391 VDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIP-----------GQKGEIGLPGP 439

Query: 345 PGTHAECAMPGAGGTHSPIAARG-RYRSHPKG----NCSPGSSPGFGELWPLGQ 393
           PG   E    G  G   P   +G   +  P G    N  PGS    GE    GQ
Sbjct: 440 PGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQ 493



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 67/289 (23%), Positives = 88/289 (30%), Gaps = 47/289 (16%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P  PPG P  P P G  G +   G    RG  G   K G   A  +  AG         T
Sbjct: 239 PMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGT 298

Query: 200 RAQAG-------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
           + + G       P         G A +S    +  P  P    P GP+  +         
Sbjct: 299 KGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG-QVGP 357

Query: 253 SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQ---RSKCGKCGTVPTQGPPGT 309
             +P           QG    +G++G    G  E+  Y         +  T+   GPPG 
Sbjct: 358 PGQPGDKGERGAAGEQGPDGPKGSKGEPGKG--EMVDYNGNINEALQEIRTLALMGPPGL 415

Query: 310 NPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY 369
             Q   PGA G                        PG   E  +PG  G       RG+ 
Sbjct: 416 PGQIGPPGAPGI-----------------------PGQKGEIGLPGPPGHDGEKGPRGK- 451

Query: 370 RSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG-GGKPSQALAAGPT 417
                    PG     G   P G+  P   +G +G  G P +    G T
Sbjct: 452 ---------PGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGET 491


>gi|22027591 alpha 1 type XIII collagen isoform 10 [Homo sapiens]
          Length = 676

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 65/253 (25%), Positives = 84/253 (33%), Gaps = 38/253 (15%)

Query: 145 GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG 204
           G P  P   G +GPR   G     GPQG   K G        P G         +  + G
Sbjct: 447 GLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDG--------PPGVKGENGHPGSPGEKG 498

Query: 205 PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQ 264
             K   G A    +      K  P   +   P GPE    P  L     P+        +
Sbjct: 499 -EKGETGQAGSPGEKGEAGEKGNPGAEVPGLP-GPEGPPGPPGLQGVPGPK-------GE 549

Query: 265 TWRQGAGEAQGTRGGSAD----GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
               GA   +G +G   D    G+P          G  G     GPPGT     +PG +G
Sbjct: 550 AGLDGAKGEKGFQGEKGDRGPLGLP----------GASGLDGRPGPPGTPGPIGVPGPAG 599

Query: 321 TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPG 380
            +    +  +   G  G   A G PG H      G  G      +RG     PKG+    
Sbjct: 600 PKGERGS--KGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRG-----PKGDKGDQ 652

Query: 381 SSPGFGELWPLGQ 393
            +PG     PLG+
Sbjct: 653 GAPGLDAPCPLGE 665



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 72/289 (24%), Positives = 96/289 (33%), Gaps = 33/289 (11%)

Query: 113 GLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQG 172
           G +  +G+   + +   AG  ++    P+ PPG P      G  GP  L G     GP+G
Sbjct: 134 GDKGAIGMPGRVGSPGDAGLSIIG---PRGPPGQPGTRGFPGFPGPIGLDGKPGHPGPKG 190

Query: 173 SLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG--PHKRAVGAAAGAAQSSGLFSKWVPCQ 230
            +  +G        P G          + Q G  PH R   + A      G      P  
Sbjct: 191 DMGLTG--------PPGQPGPQGQKGEKGQCGEYPH-RGEQSQASIQGPPGPPGPPGPSG 241

Query: 231 PLSQHPTGPEPSSRPHALSTAASPR--PCWGAGHSQTWRQGAGEAQGTRGGSADGIPELT 288
           PL  HP  P P   P  L     P+  P     H +   +G     G  G  A G P + 
Sbjct: 242 PLG-HPGLPGPMG-PPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHG--AKGAPGIA 297

Query: 289 CYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRS---KCGKCGTVTAQGPP 345
                  G+ G   T+G  G      +PG  G +        S     G+ G     GPP
Sbjct: 298 V--AGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPP 355

Query: 346 GTHAECAM------PGAGGTHSPIAARGRYRSHPKGNCSPGSSPGFGEL 388
           G   E  +      PG  G      A G     P G       PG GE+
Sbjct: 356 GPKGEAGVDGQVGPPGQPGDKGERGAAG--EQGPDGPKGSKGEPGKGEM 402



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 67/289 (23%), Positives = 88/289 (30%), Gaps = 47/289 (16%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P  PPG P  P P G  G +   G    RG  G   K G   A  +  AG         T
Sbjct: 251 PMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGT 310

Query: 200 RAQAG-------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
           + + G       P         G A +S    +  P  P    P GP+  +         
Sbjct: 311 KGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG-QVGP 369

Query: 253 SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQ---RSKCGKCGTVPTQGPPGT 309
             +P           QG    +G++G    G  E+  Y         +  T+   GPPG 
Sbjct: 370 PGQPGDKGERGAAGEQGPDGPKGSKGEPGKG--EMVDYNGNINEALQEIRTLALMGPPGL 427

Query: 310 NPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY 369
             Q   PGA G                        PG   E  +PG  G       RG+ 
Sbjct: 428 PGQIGPPGAPGI-----------------------PGQKGEIGLPGPPGHDGEKGPRGK- 463

Query: 370 RSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG-GGKPSQALAAGPT 417
                    PG     G   P G+  P   +G +G  G P +    G T
Sbjct: 464 ---------PGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGET 503


>gi|22027577 alpha 1 type XIII collagen isoform 5 [Homo sapiens]
          Length = 695

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 65/253 (25%), Positives = 84/253 (33%), Gaps = 38/253 (15%)

Query: 145 GGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG 204
           G P  P   G +GPR   G     GPQG   K G        P G         +  + G
Sbjct: 466 GLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDG--------PPGVKGENGHPGSPGEKG 517

Query: 205 PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQ 264
             K   G A    +      K  P   +   P GPE    P  L     P+        +
Sbjct: 518 -EKGETGQAGSPGEKGEAGEKGNPGAEVPGLP-GPEGPPGPPGLQGVPGPK-------GE 568

Query: 265 TWRQGAGEAQGTRGGSAD----GIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASG 320
               GA   +G +G   D    G+P          G  G     GPPGT     +PG +G
Sbjct: 569 AGLDGAKGEKGFQGEKGDRGPLGLP----------GASGLDGRPGPPGTPGPIGVPGPAG 618

Query: 321 TRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRYRSHPKGNCSPG 380
            +    +  +   G  G   A G PG H      G  G      +RG     PKG+    
Sbjct: 619 PKGERGS--KGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRG-----PKGDKGDQ 671

Query: 381 SSPGFGELWPLGQ 393
            +PG     PLG+
Sbjct: 672 GAPGLDAPCPLGE 684



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 72/305 (23%), Positives = 100/305 (32%), Gaps = 46/305 (15%)

Query: 113 GLEAGVGVGCGLRTAQPAGFELLAWQHPQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQG 172
           G +  +G+   + +   AG  ++    P+ PPG P      G  GP  L G     GP+G
Sbjct: 134 GDKGAIGMPGRVGSPGDAGLSIIG---PRGPPGQPGTRGFPGFPGPIGLDGKPGHPGPKG 190

Query: 173 SLCKSGLCCAHPVRPAGHVACGAGIWTRAQAG--PHKRAVGAAAGAAQSSGLFS-KWVPC 229
            +  +G        P G          + Q G  PH+  + +   A +SS + + K    
Sbjct: 191 DMGLTG--------PPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKGEQS 242

Query: 230 QPLSQHPTGPE-PSSRPHALSTAASPRPCWGAG----------------HSQTWRQGAGE 272
           Q   Q P GP  P      L     P P    G                H +   +G   
Sbjct: 243 QASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPG 302

Query: 273 AQGTRGGSADGIPELTCYQRSKCGKCGTVPTQGPPGTNPQCAMPGASGTRSPIATRRRS- 331
             G  G  A G P +        G+ G   T+G  G      +PG  G +        S 
Sbjct: 303 MPGKHG--AKGAPGIAV--AGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSI 358

Query: 332 --KCGKCGTVTAQGPPGTHAECAM------PGAGGTHSPIAARGRYRSHPKGNCSPGSSP 383
               G+ G     GPPG   E  +      PG  G      A G     P G       P
Sbjct: 359 GGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAG--EQGPDGPKGSKGEP 416

Query: 384 GFGEL 388
           G GE+
Sbjct: 417 GKGEM 421



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 67/289 (23%), Positives = 88/289 (30%), Gaps = 47/289 (16%)

Query: 140 PQKPPGGPQRPSPGGLRGPRSLSGSSPWRGPQGSLCKSGLCCAHPVRPAGHVACGAGIWT 199
           P  PPG P  P P G  G +   G    RG  G   K G   A  +  AG         T
Sbjct: 270 PMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGT 329

Query: 200 RAQAG-------PHKRAVGAAAGAAQSSGLFSKWVPCQPLSQHPTGPEPSSRPHALSTAA 252
           + + G       P         G A +S    +  P  P    P GP+  +         
Sbjct: 330 KGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG-QVGP 388

Query: 253 SPRPCWGAGHSQTWRQGAGEAQGTRGGSADGIPELTCYQ---RSKCGKCGTVPTQGPPGT 309
             +P           QG    +G++G    G  E+  Y         +  T+   GPPG 
Sbjct: 389 PGQPGDKGERGAAGEQGPDGPKGSKGEPGKG--EMVDYNGNINEALQEIRTLALMGPPGL 446

Query: 310 NPQCAMPGASGTRSPIATRRRSKCGKCGTVTAQGPPGTHAECAMPGAGGTHSPIAARGRY 369
             Q   PGA G                        PG   E  +PG  G       RG+ 
Sbjct: 447 PGQIGPPGAPGI-----------------------PGQKGEIGLPGPPGHDGEKGPRGK- 482

Query: 370 RSHPKGNCSPGSSPGFGELWPLGQQCPCVAQGPHG-GGKPSQALAAGPT 417
                    PG     G   P G+  P   +G +G  G P +    G T
Sbjct: 483 ---------PGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGET 522


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,936,900
Number of Sequences: 37866
Number of extensions: 2504426
Number of successful extensions: 17461
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 443
Number of HSP's that attempted gapping in prelim test: 10180
Number of HSP's gapped (non-prelim): 3040
length of query: 755
length of database: 18,247,518
effective HSP length: 110
effective length of query: 645
effective length of database: 14,082,258
effective search space: 9083056410
effective search space used: 9083056410
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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