Guide to the Human Genome
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Search of human proteins with 239756278

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239756278 PREDICTED: hypothetical protein XP_002344871 [Homo
sapiens]
         (238 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239756278 PREDICTED: hypothetical protein XP_002344871 [Homo ...   486   e-138
gi|239750809 PREDICTED: hypothetical protein XP_002347567 [Homo ...   486   e-138
gi|239745169 PREDICTED: hypothetical protein XP_002343388 [Homo ...   486   e-138
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       51   8e-07
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]        51   8e-07
gi|33286446 opioid growth factor receptor [Homo sapiens]               50   1e-06
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                    50   1e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    50   2e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    50   2e-06
gi|50511941 EMI domain containing 1 [Homo sapiens]                     50   2e-06
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      49   5e-06
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    47   1e-05
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    47   1e-05
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    47   1e-05
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         47   1e-05
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    47   1e-05
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     46   3e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    45   4e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    45   4e-05
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    45   6e-05
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    45   6e-05
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    45   6e-05
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    45   6e-05
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        45   6e-05
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      45   7e-05
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     44   9e-05
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       44   1e-04
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]       44   1e-04
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    44   1e-04
gi|6754638 microtubule-associated protein tau isoform 2 [Homo sa...    44   2e-04

>gi|239756278 PREDICTED: hypothetical protein XP_002344871 [Homo
           sapiens]
          Length = 238

 Score =  486 bits (1252), Expect = e-138
 Identities = 238/238 (100%), Positives = 238/238 (100%)

Query: 1   MMSKGTQTRLAQIPEQARFLMNLLVTDLNTVVRQVDHNTMKLTEQRAYEDDDLHGGGELA 60
           MMSKGTQTRLAQIPEQARFLMNLLVTDLNTVVRQVDHNTMKLTEQRAYEDDDLHGGGELA
Sbjct: 1   MMSKGTQTRLAQIPEQARFLMNLLVTDLNTVVRQVDHNTMKLTEQRAYEDDDLHGGGELA 60

Query: 61  VQLRLAELPERAAVHTRSLGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGAS 120
           VQLRLAELPERAAVHTRSLGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGAS
Sbjct: 61  VQLRLAELPERAAVHTRSLGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGAS 120

Query: 121 PPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHK 180
           PPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHK
Sbjct: 121 PPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHK 180

Query: 181 KAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           KAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG
Sbjct: 181 KAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238


>gi|239750809 PREDICTED: hypothetical protein XP_002347567 [Homo
           sapiens]
          Length = 238

 Score =  486 bits (1252), Expect = e-138
 Identities = 238/238 (100%), Positives = 238/238 (100%)

Query: 1   MMSKGTQTRLAQIPEQARFLMNLLVTDLNTVVRQVDHNTMKLTEQRAYEDDDLHGGGELA 60
           MMSKGTQTRLAQIPEQARFLMNLLVTDLNTVVRQVDHNTMKLTEQRAYEDDDLHGGGELA
Sbjct: 1   MMSKGTQTRLAQIPEQARFLMNLLVTDLNTVVRQVDHNTMKLTEQRAYEDDDLHGGGELA 60

Query: 61  VQLRLAELPERAAVHTRSLGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGAS 120
           VQLRLAELPERAAVHTRSLGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGAS
Sbjct: 61  VQLRLAELPERAAVHTRSLGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGAS 120

Query: 121 PPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHK 180
           PPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHK
Sbjct: 121 PPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHK 180

Query: 181 KAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           KAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG
Sbjct: 181 KAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238


>gi|239745169 PREDICTED: hypothetical protein XP_002343388 [Homo
           sapiens]
          Length = 238

 Score =  486 bits (1252), Expect = e-138
 Identities = 238/238 (100%), Positives = 238/238 (100%)

Query: 1   MMSKGTQTRLAQIPEQARFLMNLLVTDLNTVVRQVDHNTMKLTEQRAYEDDDLHGGGELA 60
           MMSKGTQTRLAQIPEQARFLMNLLVTDLNTVVRQVDHNTMKLTEQRAYEDDDLHGGGELA
Sbjct: 1   MMSKGTQTRLAQIPEQARFLMNLLVTDLNTVVRQVDHNTMKLTEQRAYEDDDLHGGGELA 60

Query: 61  VQLRLAELPERAAVHTRSLGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGAS 120
           VQLRLAELPERAAVHTRSLGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGAS
Sbjct: 61  VQLRLAELPERAAVHTRSLGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGAS 120

Query: 121 PPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHK 180
           PPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHK
Sbjct: 121 PPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHK 180

Query: 181 KAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           KAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG
Sbjct: 181 KAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 51.2 bits (121), Expect = 8e-07
 Identities = 50/166 (30%), Positives = 61/166 (36%), Gaps = 23/166 (13%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTS-PT 152
           P P  S G  G P      L  P+G+S  PG+ G AG    PG+ GA      V  S P 
Sbjct: 599 PGPPGSIGIRGQPGSMG--LPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPV 656

Query: 153 PAPGRRGGREARLRPMPT-------PSWIPVSSHKKAARSEPAE--------RRPSLLQG 197
             PG  G R  +  P PT       P   P    K   +  P +         R      
Sbjct: 657 GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNP 716

Query: 198 GQRGPAHSTGMETQKEAFDGQGGRSPLPLP-----PSTAGPPPLEG 238
           G+RG    TG+  +K    G G   P   P     P   GPP L+G
Sbjct: 717 GERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQG 762



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 46/157 (29%), Positives = 55/157 (35%), Gaps = 37/157 (23%)

Query: 87  LAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAA----- 141
           L G    P P    GE G P PR        G   PPG  G  G+    G  GA      
Sbjct: 799 LPGPLGPPGPAGPTGEKGEPGPR--------GLVGPPGSRGNPGSRGENGPTGAVGFAGP 850

Query: 142 ---DGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGG 198
              DG P V   P   PG++G   +     P P  +  S         P       L+GG
Sbjct: 851 QGPDGQPGVKGEP-GEPGQKGDAGS-----PGPQGLAGSPGPHGPNGVPG------LKGG 898

Query: 199 Q--RGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGP 233
           +  +GP  +TG       F G  GR   P P    GP
Sbjct: 899 RGTQGPPGATG-------FPGSAGRVGPPGPAGAPGP 928



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 47/150 (31%), Positives = 56/150 (37%), Gaps = 16/150 (10%)

Query: 89   GIWRDPAPVMSHGEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAGA-ADGSPH 146
            G+   P P   HG  G P  +  R    P GA+  PG  GR G    PG AGA     P 
Sbjct: 879  GLAGSPGP---HGPNGVPGLKGGRGTQGPPGATGFPGSAGRVG---PPGPAGAPGPAGPL 932

Query: 147  VSTSPTPAPGRRG--GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAH 204
                    PG RG  G   R+     P+  P     K    E  +  P     G  GPA 
Sbjct: 933  GEPGKEGPPGLRGDPGSHGRVGDR-GPAGPPGGPGDKGDPGEDGQPGPD----GPPGPAG 987

Query: 205  STGMETQKEAFDGQGGRSPLPLPPSTAGPP 234
            +TG +       GQ G   +P  P  AG P
Sbjct: 988  TTG-QRGIVGMPGQRGERGMPGLPGPAGTP 1016



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 20/152 (13%)

Query: 96  PVMSHGEAGTPAPRAARLGA--PRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSP-- 151
           P    GE G P P    +G+  P G    PGE+G  G   +PGE G A GSP     P  
Sbjct: 235 PTGPPGEPGDPGPMGP-IGSRGPEGPPGKPGEDGEPGRNGNPGEVGFA-GSPGARGFPGA 292

Query: 152 TPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQ 211
              PG +G R  +    P        S  +A  + P          G  GP    GM  +
Sbjct: 293 PGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPM---------GAMGPLGPRGMPGE 343

Query: 212 K-----EAFDGQGGRSPLPLPPSTAGPPPLEG 238
           +     +   GQ G   +P  P   GP  + G
Sbjct: 344 RGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPG 375



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 47/153 (30%), Positives = 60/153 (39%), Gaps = 35/153 (22%)

Query: 101 GEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAGA--ADGSPHV-----STSPT 152
           G  G P P+ A+    P G+S P G +G  G    PG  GA    G+P V        P 
Sbjct: 531 GSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPL 590

Query: 153 PAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAER-----RPSLLQGGQRGPAHSTG 207
            APG  G      RP P P  I +       R +P        + S    G+ G A + G
Sbjct: 591 GAPGEDG------RPGP-PGSIGI-------RGQPGSMGLPGPKGSSGDPGKPGEAGNAG 636

Query: 208 METQKEA--FDGQGGRSPLPLPPSTAGPPPLEG 238
           +  Q+ A   DG+ G      P    GPP L G
Sbjct: 637 VPGQRGAPGKDGEVG------PSGPVGPPGLAG 663



 Score = 36.2 bits (82), Expect = 0.026
 Identities = 41/151 (27%), Positives = 59/151 (39%), Gaps = 17/151 (11%)

Query: 96  PVMSHGEAGTPA-PRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA--------ADGSPH 146
           P+   G +G P  P       P GA  P G +G+ G    PG  G+         DG+P 
Sbjct: 370 PLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPG 429

Query: 147 VSTSPTPAPGRRGGREARLRP-MPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPA 203
            +  PT +PG  G   +   P  P P     S+  +  R +P +      +G  G +G  
Sbjct: 430 -AKGPTGSPGTSGPPGSAGPPGSPGPQG---STGPQGIRGQPGDPGVPGFKGEAGPKGEP 485

Query: 204 HSTGMETQKEAFDGQGGRSPLPLPPSTAGPP 234
              G++        +G R P    P T GPP
Sbjct: 486 GPHGIQGPIGPPGEEGKRGPRG-DPGTVGPP 515



 Score = 36.2 bits (82), Expect = 0.026
 Identities = 39/141 (27%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 99   SHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG-AADGSPHVSTSPTPAPGR 157
            S G  G P P  A    P G    PG+EG  G    PG  G   D  P     P   PG 
Sbjct: 913  SAGRVGPPGPAGAP--GPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP---AGPPGGPGD 967

Query: 158  RGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDG 217
            +G      +P P     P  +  +        +R      G  GPA + G      A   
Sbjct: 968  KGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGD 1027

Query: 218  QGGRSPLPLPPSTAGPPPLEG 238
            +G       PP   GPP   G
Sbjct: 1028 KG-------PPGPVGPPGSNG 1041



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 45/146 (30%), Positives = 56/146 (38%), Gaps = 19/146 (13%)

Query: 101 GEAGTPAPRAARLGAP--RGASPPPGEEGRAGAWRSPGEAGAADGSPHV--STSPTPAPG 156
           GE G   P+    GAP  RGA   PG+ G  G    PG +G   G+P +     PT A G
Sbjct: 342 GERGRLGPQ----GAPGQRGAHGMPGKPGPMGPLGIPGSSG-FPGNPGMKGEAGPTGARG 396

Query: 157 RRG--GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGME 209
             G  G+     P P P   P           P  + P+   G     G  GP  S G +
Sbjct: 397 PEGPQGQRGETGP-PGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQ 455

Query: 210 --TQKEAFDGQGGRSPLPLPPSTAGP 233
             T  +   GQ G   +P     AGP
Sbjct: 456 GSTGPQGIRGQPGDPGVPGFKGEAGP 481



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 42/155 (27%), Positives = 57/155 (36%), Gaps = 28/155 (18%)

Query: 96   PVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAA--DGSPHVSTSPTP 153
            P  S+G  G P P       P G    PG +G  G     G+ G A   GS     +P P
Sbjct: 1036 PPGSNGPVGEPGPEG-----PAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGP 1090

Query: 154  --APGRRG--GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--------GQRG 201
              APG  G  G      P+  P        +   R  P  + P   +G        GQ+G
Sbjct: 1091 VGAPGDAGQRGDPGSRGPIGPPG-------RAGKRGLPGPQGPRGDKGDHGDRGDRGQKG 1143

Query: 202  PAHSTGME--TQKEAFDGQGGRSPLPLPPSTAGPP 234
                TG++        +G+ G + +P P    GPP
Sbjct: 1144 HRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPP 1178



 Score = 34.3 bits (77), Expect = 0.097
 Identities = 50/177 (28%), Positives = 62/177 (35%), Gaps = 27/177 (15%)

Query: 82  GRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAA 141
           G V  + GI   P P    G  G+  PR  R   P+G   P G +G  G    PG+ G A
Sbjct: 119 GLVPVVTGIRGRPGPA---GPPGSQGPRGER--GPKGRPGPRGPQGIDGEPGVPGQPG-A 172

Query: 142 DGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEP-AERRPSLLQG--- 197
            G P   + P P  G      A++  +   S +            P   R P  LQG   
Sbjct: 173 PGPPGHPSHPGP-DGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQG 231

Query: 198 --------------GQRGPAHSTGME--TQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                         G  GP  S G E    K   DG+ GR+  P     AG P   G
Sbjct: 232 GAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARG 288



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 43/151 (28%), Positives = 54/151 (35%), Gaps = 31/151 (20%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAP-GRRG 159
           G AG   P   + G+P G S  PG+ G  G    PGE G A          TP P G RG
Sbjct: 732 GMAGGHGPDGPK-GSP-GPSGTPGDTGPPGLQGMPGERGIAG---------TPGPKGDRG 780

Query: 160 GREAR----------LRPMPTPSWIPVSSHKKAARSEPAER--------RPSLLQGGQRG 201
           G   +           R +P P   P  +     + EP  R        R +    G+ G
Sbjct: 781 GIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENG 840

Query: 202 PAHSTGMETQKEAFDGQGGRSPLPLPPSTAG 232
           P  + G     +  DGQ G    P  P   G
Sbjct: 841 PTGAVGF-AGPQGPDGQPGVKGEPGEPGQKG 870



 Score = 31.6 bits (70), Expect = 0.63
 Identities = 44/141 (31%), Positives = 52/141 (36%), Gaps = 32/141 (22%)

Query: 101  GEAGTPAPRAARLGA-----PRGASPPPGEEGRAGAWRSPGEAGAA--DGSPHVSTSPTP 153
            G AGTP  +    GA     P G   PPG  G  G    PG  G A  DG+P        
Sbjct: 1011 GPAGTPG-KVGPTGATGDKGPPGPVGPPGSNGPVG---EPGPEGPAGNDGTP----GRDG 1062

Query: 154  APGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQ 211
            A G RG R       P P+ +P       ++  P    P    G  GQRG   S G    
Sbjct: 1063 AVGERGDRGD-----PGPAGLP------GSQGAPGTPGPVGAPGDAGQRGDPGSRG---- 1107

Query: 212  KEAFDGQGGRSPLPLPPSTAG 232
                 G+ G+  LP P    G
Sbjct: 1108 PIGPPGRAGKRGLPGPQGPRG 1128



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 24/73 (32%), Positives = 28/73 (38%), Gaps = 12/73 (16%)

Query: 94   PAPVMSHGEAGTPAPRAARLGAP--------RGASPPPGEEGRAGAWRSPGEAGAADG-- 143
            P PV   G+ G P P    +G P         G   PPGE G  G    PG   AA G  
Sbjct: 1178 PGPVGPSGKEGNPGPLGP-IGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDI 1236

Query: 144  -SPHVSTSPTPAP 155
               +  + P P P
Sbjct: 1237 MGHYDESMPDPLP 1249



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 26/78 (33%), Positives = 29/78 (37%), Gaps = 14/78 (17%)

Query: 87   LAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPH 146
            L G+   P P    G AG P P   R         PPG  G +G   +PG  G   G P 
Sbjct: 1150 LQGLPGPPGPNGEQGSAGIPGPFGPR--------GPPGPVGPSGKEGNPGPLGPI-GPPG 1200

Query: 147  VSTS-----PTPAPGRRG 159
            V  S     P   PG  G
Sbjct: 1201 VRGSVGEAGPEGPPGEPG 1218


>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score = 51.2 bits (121), Expect = 8e-07
 Identities = 50/155 (32%), Positives = 60/155 (38%), Gaps = 31/155 (20%)

Query: 93  DPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAA--DGSPHVSTS 150
           DP      GE G P       G P G+S P G+EG+ G    PGE G A  +G+P     
Sbjct: 363 DPGAFGLKGEKGEPGADG-EAGRP-GSSGPSGDEGQPGEPGPPGEKGEAGDEGNP----G 416

Query: 151 PTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----------GQ 199
           P  APG RGG   R  P  TP         +  R +P E  P   QG           G+
Sbjct: 417 PDGAPGERGGPGER-GPRGTPG-------TRGPRGDPGEAGPQGDQGREGPVGVPGDPGE 468

Query: 200 RGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPP 234
            GP    G    +     +G R      P  AGPP
Sbjct: 469 AGPIGPKGYRGDEGPPGSEGARG----APGPAGPP 499



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 47/148 (31%), Positives = 56/148 (37%), Gaps = 26/148 (17%)

Query: 101 GEAGTPAPRAARLGAPR--GASPPPGEEGRAGAWRSPGEAG--AADGSPHVSTSPTPA-- 154
           GE G P     + G+P   G   PPG +G  GA+   GE G   ADG      S  P+  
Sbjct: 335 GEMGYPGLPGCK-GSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGD 393

Query: 155 ---------PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHS 205
                    PG +G  EA     P P   P        R  P ER P     G RGP   
Sbjct: 394 EGQPGEPGPPGEKG--EAGDEGNPGPDGAP------GERGGPGERGPRGTP-GTRGPRGD 444

Query: 206 TGMETQKEAFDGQGGRSPLPLPPSTAGP 233
            G E   +   G+ G   +P  P  AGP
Sbjct: 445 PG-EAGPQGDQGREGPVGVPGDPGEAGP 471



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 34/123 (27%), Positives = 41/123 (33%), Gaps = 27/123 (21%)

Query: 116 PRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIP 175
           P G    PG EG  G    PGE G A G P              GR   L P+       
Sbjct: 258 PPGLRGDPGFEGERGKPGLPGEKGEA-GDP--------------GRPGDLGPVGYQG--- 299

Query: 176 VSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPP 235
               +K +R E   R P     G +G     G+    +  DG  G    P  P   G P 
Sbjct: 300 -MKGEKGSRGEKGSRGPK----GYKGEKGKRGI----DGVDGVKGEMGYPGLPGCKGSPG 350

Query: 236 LEG 238
            +G
Sbjct: 351 FDG 353



 Score = 28.9 bits (63), Expect = 4.1
 Identities = 40/142 (28%), Positives = 47/142 (33%), Gaps = 25/142 (17%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
           GEAG   P+  R     G   PPG EG  GA   PG AG           P   PG  G 
Sbjct: 467 GEAGPIGPKGYR-----GDEGPPGSEGARGA---PGPAG-----------PPGDPGLMGE 507

Query: 161 R----EARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFD 216
           R     A       P +     ++ A      +  P L   G  G A   G +    A  
Sbjct: 508 RGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGL--KGDEGEAGDPGDDNNDIAPR 565

Query: 217 GQGGRSPLPLPPSTAGPPPLEG 238
           G  G      P    GPP  +G
Sbjct: 566 GVKGAKGYRGPEGPQGPPGHQG 587


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 54/177 (30%), Positives = 65/177 (36%), Gaps = 25/177 (14%)

Query: 80  GAGRVVRLAGIWRDPAPV----MSHGEAGTP-------APRAARLGAPR---GASP--PP 123
           G  + + LAG    PAP       H E G          P+    G+P    G SP  P 
Sbjct: 474 GGAQTLALAG---SPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPA 530

Query: 124 GEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAA 183
           G+E       +PG   A       + SP+  PG R    A   P  +PS  P  S     
Sbjct: 531 GDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 590

Query: 184 RSEPAERRPSLLQGGQ-RGPAHSTGMETQKEAFD----GQGGRSPLPLPPSTAGPPP 235
           R EPAE  PS   G +  GPA     E+  E       G  G  P   P  T GP P
Sbjct: 591 RDEPAE-SPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSP 646



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 26/96 (27%), Positives = 35/96 (36%), Gaps = 1/96 (1%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTP 153
           P P  +      PA   +    P  A P   E   + +  +PG   A       + SP+ 
Sbjct: 562 PGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPS-ETPGPRPAGPAGDEPAESPSE 620

Query: 154 APGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAE 189
            PG R    A   P  +PS  P  S     R EPA+
Sbjct: 621 TPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAK 656



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 22/79 (27%), Positives = 27/79 (34%), Gaps = 17/79 (21%)

Query: 159 GGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQ 218
           G +   L   P PS  P + H +    E  E        G+ GP         KE   G 
Sbjct: 475 GAQTLALAGSPAPSGHPKAGHSENGVEEDTE--------GRTGP---------KEGTPGS 517

Query: 219 GGRSPLPLPPSTAGPPPLE 237
              +P P P   AG  P E
Sbjct: 518 PSETPGPSPAGPAGDEPAE 536


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 48/161 (29%), Positives = 65/161 (40%), Gaps = 25/161 (15%)

Query: 94  PAPVMSHGEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAGAA-----DGSP-H 146
           P      G+ G+P  R  + +  P+GA+ PPG  G+ G   +PG  G+A      GSP H
Sbjct: 273 PGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGH 332

Query: 147 VSTSPTPA-PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-------- 197
              +  P  PG +GG     +  P P  +P  S       EP  R     QG        
Sbjct: 333 QGLAGVPGQPGTKGGPGD--QGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQ 390

Query: 198 GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G+RGP    G + ++     QG       PP   GP  L G
Sbjct: 391 GERGPVGQPGPQGRQGPKGEQG-------PPGIPGPQGLPG 424



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 44/166 (26%), Positives = 57/166 (34%), Gaps = 33/166 (19%)

Query: 101 GEAGTPAPRAARLGAPR-----GASPPPGEEGRAGAWRSPGEAG--AADGSPHVS--TSP 151
           GE G P P     G P      G + PPG+ G  G    PG+AG    DG P +   T  
Sbjct: 30  GERGPPGPPGPP-GVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGA 88

Query: 152 TPAPGRRGGREARLRP------------------MPTPSWIPVSSHKKAARSEPAERRPS 193
              PG  G    + +P                   P P  +P     +  + +P    PS
Sbjct: 89  KGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPS 148

Query: 194 LLQGGQRGPAHSTGMETQKEAFDGQGG-RSPLPLPPSTAGPPPLEG 238
               G  GP    G     +  +G      P   PP   GPP L+G
Sbjct: 149 ----GPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQG 190



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 50/159 (31%), Positives = 59/159 (37%), Gaps = 29/159 (18%)

Query: 89  GIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--AADGSPH 146
           GI   P      GE G P      +GA  GA+ PPGEEG  G    PG AG    +GSP 
Sbjct: 232 GIRGYPGMAGPKGETG-PHGYKGMVGAI-GATGPPGEEGPRG---PPGRAGEKGDEGSPG 286

Query: 147 VS-----TSPTPAPGRRG--GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQ 199
           +      T P  A G  G  G++       TP   P          +P          G 
Sbjct: 287 IRGPQGITGPKGATGPPGINGKDG------TPG-TPGMKGSAGQAGQPG-------SPGH 332

Query: 200 RGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           +G A   G    K     QG   P  L P  +GPP  EG
Sbjct: 333 QGLAGVPGQPGTKGGPGDQGEPGPQGL-PGFSGPPGKEG 370



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 8/61 (13%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAAD--GSPHVSTSPTPAPGRR 158
           G AG P  +  +     G S  PG +G+ G    PG  G +   G+P V   P P PG R
Sbjct: 445 GVAGLPGEKGEK-----GESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGP-PGPR 498

Query: 159 G 159
           G
Sbjct: 499 G 499



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 37/130 (28%), Positives = 43/130 (33%), Gaps = 25/130 (19%)

Query: 110 AARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHV----STSPTPAPGRRG--GREA 163
           A  +  P G   PPG  G+ G    PG  G       V    +T P    G +G  G   
Sbjct: 551 AVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG 610

Query: 164 RLRP-MPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRS 222
           R  P MP P  IP               RP     G+ G   S G         G+ GR 
Sbjct: 611 RGHPGMPGPPGIP-----------GLPGRPGQAINGKDGDRGSPGA-------PGEAGRP 652

Query: 223 PLPLPPSTAG 232
            LP P    G
Sbjct: 653 GLPGPVGLPG 662



 Score = 29.3 bits (64), Expect = 3.1
 Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 3/41 (7%)

Query: 101 GEAGTPAPRAARLGAP--RGASPPPGEEGRAGAWRSPGEAG 139
           GE G P P +   GAP  +G   PPG  G AG    PG+ G
Sbjct: 472 GEPGYPGP-SGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPG 511



 Score = 28.9 bits (63), Expect = 4.1
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 3/76 (3%)

Query: 96  PVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAP 155
           P    G  G P P+   L   +G    PG+ G  G    PG AG          S  P P
Sbjct: 407 PKGEQGPPGIPGPQG--LPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGP 464

Query: 156 -GRRGGREARLRPMPT 170
            G++G R     P P+
Sbjct: 465 KGQQGVRGEPGYPGPS 480


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 48/166 (28%), Positives = 64/166 (38%), Gaps = 28/166 (16%)

Query: 101 GEAGTPAPRAAR-------LGAPRGASPPPGEEGRAGAWRSPGEAG--AADGSPHVSTSP 151
           G  G P P+ AR          P+GA+  PG+ G  G   +PG  G    DG    +  P
Sbjct: 585 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 644

Query: 152 TPA--PGRRGGREA----RLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-------- 197
            PA   G RG + A      + +P P   P    K   +  P E     L G        
Sbjct: 645 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFP 704

Query: 198 GQRGPAHSTGMETQK-----EAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G+RG   + G++  +        DG  G S    PP   GPP L+G
Sbjct: 705 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQG 750



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 52/150 (34%), Positives = 62/150 (41%), Gaps = 18/150 (12%)

Query: 94   PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA--ADGSPHVSTSP 151
            P PV   G  G PA    R G+P GA  PPG +G AG     GE GA  A G+P    SP
Sbjct: 1019 PGPVGPPGLTG-PAGEPGREGSP-GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1076

Query: 152  TPA--PGRRGGR-EARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGM 208
             PA   G++G R EA  +    P      S    AR     + P     G +G A   G 
Sbjct: 1077 GPAGPTGKQGDRGEAGAQGPMGP------SGPAGARGIQGPQGPR----GDKGEAGEPG- 1125

Query: 209  ETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            E   +   G  G   LP PP  +G     G
Sbjct: 1126 ERGLKGHRGFTGLQGLPGPPGPSGDQGASG 1155



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 48/154 (31%), Positives = 58/154 (37%), Gaps = 21/154 (13%)

Query: 96  PVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAAD--------GSPHV 147
           P    GE G P P   + G P G   PPGE G+ G    PGEAGA          G P  
Sbjct: 649 PAGERGEQGAPGPSGFQ-GLP-GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 706

Query: 148 STSPTPAPGRRGGREARLRP-------MPTPSWIPVSSHKKAARSEPAERRPSLLQG--G 198
             SP  A G +G R     P          P+  P +      +  P ER  + + G  G
Sbjct: 707 RGSP-GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 765

Query: 199 QRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAG 232
            RG     G E       G+G   P+  PP  AG
Sbjct: 766 DRGDVGEKGPEGAPGKDGGRGLTGPIG-PPGPAG 798



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 41/141 (29%), Positives = 51/141 (36%), Gaps = 20/141 (14%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG-AADGSPHVSTSPTPAPGRRG 159
           G  G P P  A     +G   PPG  G AGA  +PGE G      P     P  A G+ G
Sbjct: 789 GPIGPPGPAGAN--GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 846

Query: 160 GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQG 219
            +  +             + +K     P  + PS    G  GP   TG+   K A   QG
Sbjct: 847 AKGEQ-----------GEAGQKGDAGAPGPQGPS----GAPGPQGPTGVTGPKGARGAQG 891

Query: 220 --GRSPLPLPPSTAGPPPLEG 238
             G +  P      GPP   G
Sbjct: 892 PPGATGFPGAAGRVGPPGSNG 912



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 40/133 (30%), Positives = 46/133 (34%), Gaps = 29/133 (21%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
           G  G P P       P+GA  P GEEG+ GA   PG  G           P   PG RG 
Sbjct: 468 GPKGEPGP-----AGPQGAPGPAGEEGKRGARGEPGGVG-----------PIGPPGERGA 511

Query: 161 REARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGG 220
                   P     P        +  P ER PS    G  GP  + G +  +    G  G
Sbjct: 512 --------PGNRGFPGQDGLAGPKGAPGERGPS----GLAGPKGANG-DPGRPGEPGLPG 558

Query: 221 RSPLPLPPSTAGP 233
              L   P  AGP
Sbjct: 559 ARGLTGRPGDAGP 571



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 47/158 (29%), Positives = 55/158 (34%), Gaps = 19/158 (12%)

Query: 94  PAPVMSHGEAGTPA-PRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--------AADGS 144
           P P    G  G P  P  +    PRG   PPG+ G  G    PG+AG         A G 
Sbjct: 218 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 277

Query: 145 PHVSTSPTPAPGRRG--GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQR 200
           P     P    G RG  G +        P  +   S        P    P  L G  G+ 
Sbjct: 278 PGTPGLP-GVKGHRGYPGLDGAKGEAGAPG-VKGESGSPGENGSPGPMGPRGLPGERGRT 335

Query: 201 GPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           GPA + G        DGQ G +  P P   AG P   G
Sbjct: 336 GPAGAAGARGN----DGQPGPAGPPGPVGPAGGPGFPG 369



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 46/144 (31%), Positives = 52/144 (36%), Gaps = 20/144 (13%)

Query: 94  PAPVMSHGEAGTP-APRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPT 152
           P PV   G  G P AP A     P GA  P G +G  G   +PG  G A  S +  T   
Sbjct: 356 PGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD-- 413

Query: 153 PAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMET 210
             PG +G   A     P  +  P           P  R P   QG  G  GP   TG E 
Sbjct: 414 GIPGAKGSAGA-----PGIAGAP---------GFPGPRGPPGPQGATGPLGPKGQTG-EP 458

Query: 211 QKEAFDGQGGRSPLPLPPSTAGPP 234
               F G+ G    P P    G P
Sbjct: 459 GIAGFKGEQGPKGEPGPAGPQGAP 482



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 45/133 (33%), Positives = 55/133 (41%), Gaps = 19/133 (14%)

Query: 96   PVMSHGEAGTPAPRAARLGAPRGASPP-----PGEEGRAGAWRSPGEAGAADGSPHVSTS 150
            P  + G++G P  RA   G    A PP     PG++G +GA   PG  G A     V   
Sbjct: 928  PKGARGDSGPPG-RAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVG-- 984

Query: 151  PTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGM 208
                PG+RG  E     +P PS  P    K+ A     +R P    G  G  GPA   G 
Sbjct: 985  ---LPGQRG--ERGFPGLPGPSGEP---GKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 1036

Query: 209  ETQKEAFDGQGGR 221
            E    A DG  GR
Sbjct: 1037 EGSPGA-DGPPGR 1048



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 48/153 (31%), Positives = 58/153 (37%), Gaps = 23/153 (15%)

Query: 101 GEAGTPAPRAARLGAPRGASPP--------PGEEGRAGAWRSPGEAGAADGSPHVSTSPT 152
           GE G P  R    G P  A P         PGE+GR G    PG  GA  G P V   P 
Sbjct: 552 GEPGLPGARGLT-GRPGDAGPQGKVGPSGAPGEDGRPG---PPGPQGAR-GQPGVMGFPG 606

Query: 153 P-----APGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHS 205
           P      PG+ G  E  L   P    +P    +  A   P    P+  +G  G  GP+  
Sbjct: 607 PKGANGEPGKAG--EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664

Query: 206 TGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            G+        G+GG+      P  AG P L G
Sbjct: 665 QGLPGPPGP-PGEGGKPGDQGVPGEAGAPGLVG 696



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 45/151 (29%), Positives = 57/151 (37%), Gaps = 31/151 (20%)

Query: 101  GEAGTPAPRAARLGA--PRGASP---------PPGEEGRAGAWRSPGEAGAADGSPHVST 149
            G  G   P+ AR GA  P GA+          PPG  G  G    PG +G  DG P  + 
Sbjct: 876  GPTGVTGPKGAR-GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSG-KDG-PKGAR 932

Query: 150  SPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGME 209
              +  PGR G  E  L+    P            + EP +  PS    G  GP    G+ 
Sbjct: 933  GDSGPPGRAG--EPGLQGPAGP---------PGEKGEPGDDGPS----GAEGPPGPQGLA 977

Query: 210  TQK--EAFDGQGGRSPLPLPPSTAGPPPLEG 238
             Q+      GQ G    P  P  +G P  +G
Sbjct: 978  GQRGIVGLPGQRGERGFPGLPGPSGEPGKQG 1008



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 37/142 (26%), Positives = 48/142 (33%), Gaps = 16/142 (11%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
           G  G P  R A      G + P G+ G  G     G  G   G         P P    G
Sbjct: 747 GLQGMPGERGAA-----GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 801

Query: 161 REARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQK--EAFD 216
            +  + P       P  +    AR  P ER  +   G  G  GP  + G    K  +   
Sbjct: 802 EKGEVGP-------PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEA 854

Query: 217 GQGGRSPLPLPPSTAGPPPLEG 238
           GQ G +  P P   +G P  +G
Sbjct: 855 GQKGDAGAPGPQGPSGAPGPQG 876



 Score = 32.0 bits (71), Expect = 0.48
 Identities = 37/137 (27%), Positives = 40/137 (29%), Gaps = 14/137 (10%)

Query: 101  GEAGTPAPRAARLGA-PRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRG 159
            GEAG   P      A  RG   P G  G  G    PGE G             P P    
Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1148

Query: 160  GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQKEAFDG 217
            G +    P          +     R  P    PS   G  G  GP    G    +    G
Sbjct: 1149 GDQGASGP----------AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG-PRGRSGETG 1197

Query: 218  QGGRSPLPLPPSTAGPP 234
              G    P PP   GPP
Sbjct: 1198 PAGPPGNPGPPGPPGPP 1214



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 40/153 (26%), Positives = 51/153 (33%), Gaps = 27/153 (17%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA-----ADGSPHVS 148
           P P    GE G         G P G   P GE+G  G     GE GA      DG P   
Sbjct: 100 PGPKGQKGEPGDIKDIVGPKGPP-GPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 158

Query: 149 TSPTP--------APGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQR 200
            +P P         PG  G   A++              +KA  ++    +  +   G R
Sbjct: 159 GNPGPPGPPGPPGPPGLGGNFAAQMAG---------GFDEKAGGAQLGVMQGPMGPMGPR 209

Query: 201 GPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGP 233
           GP    G     + F G  G    P  P  +GP
Sbjct: 210 GPPGPAG-APGPQGFQGNPGE---PGEPGVSGP 238



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 32/110 (29%), Positives = 39/110 (35%), Gaps = 10/110 (9%)

Query: 87   LAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPH 146
            L G+   P P    G +G   P       PRG   P G  G+ GA   PG  G     P 
Sbjct: 1138 LQGLPGPPGPSGDQGASGPAGP-----SGPRGPPGPVGPSGKDGANGIPGPIGPP--GPR 1190

Query: 147  VSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQ 196
              +  T   G  G       P P    I +S+    A   P E+ P  LQ
Sbjct: 1191 GRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF---AGLGPREKGPDPLQ 1237


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 48/166 (28%), Positives = 64/166 (38%), Gaps = 28/166 (16%)

Query: 101 GEAGTPAPRAAR-------LGAPRGASPPPGEEGRAGAWRSPGEAG--AADGSPHVSTSP 151
           G  G P P+ AR          P+GA+  PG+ G  G   +PG  G    DG    +  P
Sbjct: 516 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 575

Query: 152 TPA--PGRRGGREA----RLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-------- 197
            PA   G RG + A      + +P P   P    K   +  P E     L G        
Sbjct: 576 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFP 635

Query: 198 GQRGPAHSTGMETQK-----EAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G+RG   + G++  +        DG  G S    PP   GPP L+G
Sbjct: 636 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQG 681



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 52/150 (34%), Positives = 62/150 (41%), Gaps = 18/150 (12%)

Query: 94   PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA--ADGSPHVSTSP 151
            P PV   G  G PA    R G+P GA  PPG +G AG     GE GA  A G+P    SP
Sbjct: 950  PGPVGPPGLTG-PAGEPGREGSP-GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1007

Query: 152  TPA--PGRRGGR-EARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGM 208
             PA   G++G R EA  +    P      S    AR     + P     G +G A   G 
Sbjct: 1008 GPAGPTGKQGDRGEAGAQGPMGP------SGPAGARGIQGPQGPR----GDKGEAGEPG- 1056

Query: 209  ETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            E   +   G  G   LP PP  +G     G
Sbjct: 1057 ERGLKGHRGFTGLQGLPGPPGPSGDQGASG 1086



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 48/154 (31%), Positives = 58/154 (37%), Gaps = 21/154 (13%)

Query: 96  PVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAAD--------GSPHV 147
           P    GE G P P   + G P G   PPGE G+ G    PGEAGA          G P  
Sbjct: 580 PAGERGEQGAPGPSGFQ-GLP-GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 637

Query: 148 STSPTPAPGRRGGREARLRP-------MPTPSWIPVSSHKKAARSEPAERRPSLLQG--G 198
             SP  A G +G R     P          P+  P +      +  P ER  + + G  G
Sbjct: 638 RGSP-GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 696

Query: 199 QRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAG 232
            RG     G E       G+G   P+  PP  AG
Sbjct: 697 DRGDVGEKGPEGAPGKDGGRGLTGPIG-PPGPAG 729



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 41/141 (29%), Positives = 51/141 (36%), Gaps = 20/141 (14%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG-AADGSPHVSTSPTPAPGRRG 159
           G  G P P  A     +G   PPG  G AGA  +PGE G      P     P  A G+ G
Sbjct: 720 GPIGPPGPAGAN--GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 777

Query: 160 GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQG 219
            +  +             + +K     P  + PS    G  GP   TG+   K A   QG
Sbjct: 778 AKGEQ-----------GEAGQKGDAGAPGPQGPS----GAPGPQGPTGVTGPKGARGAQG 822

Query: 220 --GRSPLPLPPSTAGPPPLEG 238
             G +  P      GPP   G
Sbjct: 823 PPGATGFPGAAGRVGPPGSNG 843



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 40/133 (30%), Positives = 46/133 (34%), Gaps = 29/133 (21%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
           G  G P P       P+GA  P GEEG+ GA   PG  G           P   PG RG 
Sbjct: 399 GPKGEPGP-----AGPQGAPGPAGEEGKRGARGEPGGVG-----------PIGPPGERGA 442

Query: 161 REARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGG 220
                   P     P        +  P ER PS    G  GP  + G +  +    G  G
Sbjct: 443 --------PGNRGFPGQDGLAGPKGAPGERGPS----GLAGPKGANG-DPGRPGEPGLPG 489

Query: 221 RSPLPLPPSTAGP 233
              L   P  AGP
Sbjct: 490 ARGLTGRPGDAGP 502



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 47/158 (29%), Positives = 55/158 (34%), Gaps = 19/158 (12%)

Query: 94  PAPVMSHGEAGTPA-PRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--------AADGS 144
           P P    G  G P  P  +    PRG   PPG+ G  G    PG+AG         A G 
Sbjct: 149 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 208

Query: 145 PHVSTSPTPAPGRRG--GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQR 200
           P     P    G RG  G +        P  +   S        P    P  L G  G+ 
Sbjct: 209 PGTPGLP-GVKGHRGYPGLDGAKGEAGAPG-VKGESGSPGENGSPGPMGPRGLPGERGRT 266

Query: 201 GPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           GPA + G        DGQ G +  P P   AG P   G
Sbjct: 267 GPAGAAGARGN----DGQPGPAGPPGPVGPAGGPGFPG 300



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 46/144 (31%), Positives = 52/144 (36%), Gaps = 20/144 (13%)

Query: 94  PAPVMSHGEAGTP-APRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPT 152
           P PV   G  G P AP A     P GA  P G +G  G   +PG  G A  S +  T   
Sbjct: 287 PGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD-- 344

Query: 153 PAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMET 210
             PG +G   A     P  +  P           P  R P   QG  G  GP   TG E 
Sbjct: 345 GIPGAKGSAGA-----PGIAGAP---------GFPGPRGPPGPQGATGPLGPKGQTG-EP 389

Query: 211 QKEAFDGQGGRSPLPLPPSTAGPP 234
               F G+ G    P P    G P
Sbjct: 390 GIAGFKGEQGPKGEPGPAGPQGAP 413



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 45/133 (33%), Positives = 55/133 (41%), Gaps = 19/133 (14%)

Query: 96  PVMSHGEAGTPAPRAARLGAPRGASPP-----PGEEGRAGAWRSPGEAGAADGSPHVSTS 150
           P  + G++G P  RA   G    A PP     PG++G +GA   PG  G A     V   
Sbjct: 859 PKGARGDSGPPG-RAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVG-- 915

Query: 151 PTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGM 208
               PG+RG  E     +P PS  P    K+ A     +R P    G  G  GPA   G 
Sbjct: 916 ---LPGQRG--ERGFPGLPGPSGEP---GKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 967

Query: 209 ETQKEAFDGQGGR 221
           E    A DG  GR
Sbjct: 968 EGSPGA-DGPPGR 979



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 48/153 (31%), Positives = 58/153 (37%), Gaps = 23/153 (15%)

Query: 101 GEAGTPAPRAARLGAPRGASPP--------PGEEGRAGAWRSPGEAGAADGSPHVSTSPT 152
           GE G P  R    G P  A P         PGE+GR G    PG  GA  G P V   P 
Sbjct: 483 GEPGLPGARGLT-GRPGDAGPQGKVGPSGAPGEDGRPG---PPGPQGAR-GQPGVMGFPG 537

Query: 153 P-----APGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHS 205
           P      PG+ G  E  L   P    +P    +  A   P    P+  +G  G  GP+  
Sbjct: 538 PKGANGEPGKAG--EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595

Query: 206 TGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            G+        G+GG+      P  AG P L G
Sbjct: 596 QGLPGPPGP-PGEGGKPGDQGVPGEAGAPGLVG 627



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 45/151 (29%), Positives = 57/151 (37%), Gaps = 31/151 (20%)

Query: 101 GEAGTPAPRAARLGA--PRGASP---------PPGEEGRAGAWRSPGEAGAADGSPHVST 149
           G  G   P+ AR GA  P GA+          PPG  G  G    PG +G  DG P  + 
Sbjct: 807 GPTGVTGPKGAR-GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSG-KDG-PKGAR 863

Query: 150 SPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGME 209
             +  PGR G  E  L+    P            + EP +  PS    G  GP    G+ 
Sbjct: 864 GDSGPPGRAG--EPGLQGPAGP---------PGEKGEPGDDGPS----GAEGPPGPQGLA 908

Query: 210 TQK--EAFDGQGGRSPLPLPPSTAGPPPLEG 238
            Q+      GQ G    P  P  +G P  +G
Sbjct: 909 GQRGIVGLPGQRGERGFPGLPGPSGEPGKQG 939



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 37/142 (26%), Positives = 48/142 (33%), Gaps = 16/142 (11%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
           G  G P  R A      G + P G+ G  G     G  G   G         P P    G
Sbjct: 678 GLQGMPGERGAA-----GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 732

Query: 161 REARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQK--EAFD 216
            +  + P       P  +    AR  P ER  +   G  G  GP  + G    K  +   
Sbjct: 733 EKGEVGP-------PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEA 785

Query: 217 GQGGRSPLPLPPSTAGPPPLEG 238
           GQ G +  P P   +G P  +G
Sbjct: 786 GQKGDAGAPGPQGPSGAPGPQG 807



 Score = 32.7 bits (73), Expect = 0.28
 Identities = 41/155 (26%), Positives = 52/155 (33%), Gaps = 27/155 (17%)

Query: 92  RDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA-----ADGSPH 146
           R P P    GE G         G P G   P GE+G  G     GE GA      DG P 
Sbjct: 29  RQPGPKGQKGEPGDIKDIVGPKGPP-GPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPG 87

Query: 147 VSTSPTP--------APGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGG 198
              +P P         PG  G   A++              +KA  ++    +  +   G
Sbjct: 88  TPGNPGPPGPPGPPGPPGLGGNFAAQMAG---------GFDEKAGGAQLGVMQGPMGPMG 138

Query: 199 QRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGP 233
            RGP    G     + F G  G    P  P  +GP
Sbjct: 139 PRGPPGPAG-APGPQGFQGNPGE---PGEPGVSGP 169



 Score = 32.0 bits (71), Expect = 0.48
 Identities = 37/137 (27%), Positives = 40/137 (29%), Gaps = 14/137 (10%)

Query: 101  GEAGTPAPRAARLGA-PRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRG 159
            GEAG   P      A  RG   P G  G  G    PGE G             P P    
Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1079

Query: 160  GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQKEAFDG 217
            G +    P          +     R  P    PS   G  G  GP    G    +    G
Sbjct: 1080 GDQGASGP----------AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG-PRGRSGETG 1128

Query: 218  QGGRSPLPLPPSTAGPP 234
              G    P PP   GPP
Sbjct: 1129 PAGPPGNPGPPGPPGPP 1145



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 32/110 (29%), Positives = 39/110 (35%), Gaps = 10/110 (9%)

Query: 87   LAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPH 146
            L G+   P P    G +G   P       PRG   P G  G+ GA   PG  G     P 
Sbjct: 1069 LQGLPGPPGPSGDQGASGPAGP-----SGPRGPPGPVGPSGKDGANGIPGPIGPP--GPR 1121

Query: 147  VSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQ 196
              +  T   G  G       P P    I +S+    A   P E+ P  LQ
Sbjct: 1122 GRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF---AGLGPREKGPDPLQ 1168


>gi|50511941 EMI domain containing 1 [Homo sapiens]
          Length = 443

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 50/166 (30%), Positives = 64/166 (38%), Gaps = 23/166 (13%)

Query: 78  SLGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGE 137
           S G G +    G W  P P    G+AG+  P   R   P G   PPG  GRAGA  +PGE
Sbjct: 188 SPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMR--GPPGPQGPPGSPGRAGAVGTPGE 245

Query: 138 AGAADGSPHVSTSPTPAPGRRGGREARLR----PMPTPSWIPVSSH-KKAARSEPAERRP 192
            G   G P     P P P   G   AR+     P+ + ++   ++H  +     P    P
Sbjct: 246 RG-PPGPPGPPGPPGP-PAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGPPGP 303

Query: 193 SLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                G  GP   TG+        G  G      PP   GP  + G
Sbjct: 304 M----GPPGPPGPTGV-------PGSPGHIG---PPGPTGPKGISG 335



 Score = 34.3 bits (77), Expect = 0.097
 Identities = 44/154 (28%), Positives = 50/154 (32%), Gaps = 39/154 (25%)

Query: 106 PAPRAARLGAPRGASPP----PGEEG---RAGAWRSPGEAGAADGSPHVSTSPTPAPGRR 158
           P P      AP    PP    PG+ G   + GAW  PG  G           P    G R
Sbjct: 168 PTPATPEDPAPLWGPPPAQGSPGDGGLQDQVGAWGLPGPTG-----------PKGDAGSR 216

Query: 159 GGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQKEAFD 216
           G     +R  P P   P S  +  A   P ER P    G  G  GP    G    + +  
Sbjct: 217 G--PMGMRGPPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQH 274

Query: 217 G----------------QGGRSPLPLPPSTAGPP 234
           G                QG   P P PP   GPP
Sbjct: 275 GDPLLSNTFTETNNHWPQGPTGP-PGPPGPMGPP 307



 Score = 31.6 bits (70), Expect = 0.63
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 11/62 (17%)

Query: 99  SHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAAD--GSPHVSTSPTPAPG 156
           S G  G P P       P+G S  PGE+G  G    PG  G+A   G P     P   PG
Sbjct: 318 SPGHIGPPGPTG-----PKGISGHPGEKGERGLRGEPGPQGSAGQRGEP----GPKGDPG 368

Query: 157 RR 158
            +
Sbjct: 369 EK 370


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 50/156 (32%), Positives = 56/156 (35%), Gaps = 25/156 (16%)

Query: 96   PVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHV-----STS 150
            P  + GE G P P       P G + PPGE GR GA  + G  G  DGSP        T 
Sbjct: 987  PSGASGERGPPGPMG-----PPGLAGPPGESGREGAPGAEGSPG-RDGSPGAKGDRGETG 1040

Query: 151  PTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMET 210
            P   PG  G   A   P P     P         + PA     +   G RGPA   G   
Sbjct: 1041 PAGPPGAPGAPGA---PGPVG---PAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRG 1094

Query: 211  QKEAFDGQGGR--------SPLPLPPSTAGPPPLEG 238
             K     QG R        S L  PP   G P  +G
Sbjct: 1095 DKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQG 1130



 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 51/173 (29%), Positives = 65/173 (37%), Gaps = 28/173 (16%)

Query: 94  PAPVMSHGEAGTPAPRAARLGA-------PRGASPPPGEEGRAGAWRSPGEAGAA--DGS 144
           P P    G  G P P  AR  A       P+GA+  PG+ G  G    PG  G A  DG 
Sbjct: 556 PGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGE 615

Query: 145 PHVSTSPTPA--PGRRGGREARLRP----MPTPSWIPVSSHKKAARSEPAE---RRPSLL 195
                 P PA   G RG +     P    +P P+  P  + K   +  P +     PS  
Sbjct: 616 AGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGA 675

Query: 196 QG--------GQRGPAHSTGMETQKEA--FDGQGGRSPLPLPPSTAGPPPLEG 238
           +G        G +GP    G      A   DG  G +  P  P + G P L+G
Sbjct: 676 RGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQG 728



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 42/135 (31%), Positives = 48/135 (35%), Gaps = 40/135 (29%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA-ADGSPHVSTSPTPAPGRRG 159
           G+ G P P       P G + PPG +G+ GA   PG+AGA  D  P     P   PG  G
Sbjct: 800 GDRGEPGPPG-----PAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854

Query: 160 GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQG 219
              A                 K AR             G  GP  +TG       F G  
Sbjct: 855 NVGA--------------PGAKGAR-------------GSAGPPGATG-------FPGAA 880

Query: 220 GRSPLPLPPSTAGPP 234
           GR   P P   AGPP
Sbjct: 881 GRVGPPGPSGNAGPP 895



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 54/161 (33%), Positives = 62/161 (38%), Gaps = 29/161 (18%)

Query: 87  LAGIWRDPAPVMSHGEAGTPAPRAA--RLGAPRGASPPPGEEGRAGAWRSPGEAGAA--D 142
           L G   D  P    GE G+P    A  ++G PRG    PGE GR GA   PG AGA   D
Sbjct: 273 LDGAKGDAGPAGPKGEPGSPGENGAPGQMG-PRGL---PGERGRPGA---PGPAGARGND 325

Query: 143 GS-----PHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG 197
           G+     P   T P   PG  G   A  +    P     S   +  R EP    P+    
Sbjct: 326 GATGAAGPPGPTGPAGPPGFPGAVGA--KGEAGPQGPRGSEGPQGVRGEPGPPGPA---- 379

Query: 198 GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G  GPA + G        DGQ G       P  AG P   G
Sbjct: 380 GAAGPAGNPGA-------DGQPGAKGANGAPGIAGAPGFPG 413



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 44/150 (29%), Positives = 56/150 (37%), Gaps = 26/150 (17%)

Query: 89  GIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVS 148
           G+   P      G+ G P P A + G P G   PPG  G+AG    PG  GAA       
Sbjct: 539 GLTGSPGSPGPDGKTGPPGP-AGQDGRP-GPPGPPGARGQAGVMGFPGPKGAAG------ 590

Query: 149 TSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGM 208
                 PG+ G R     P P  +  P     +A    P        + G++GPA S G 
Sbjct: 591 -----EPGKAGERGV---PGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF 642

Query: 209 ETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
               +   G  G      PP  AG P  +G
Sbjct: 643 ----QGLPGPAG------PPGEAGKPGEQG 662



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 51/172 (29%), Positives = 59/172 (34%), Gaps = 29/172 (16%)

Query: 88   AGIWRDPAPVMSHGEAGTPAPRAARLGA-PRGASP---------PPGEEGRAGAWRSPGE 137
            AG    P P+   G  G P  + AR  A P GA+          PPG  G AG    PG 
Sbjct: 844  AGPAGPPGPI---GNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGP 900

Query: 138  AGAADG-SPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQ 196
            AG   G  P   T P   PG  G         P P+    S         P    P  + 
Sbjct: 901  AGKEGGKGPRGETGPAGRPGEVGPPGP-----PGPAGEKGSPGADGPAGAPGTPGPQGIA 955

Query: 197  G--------GQRGPAHSTGM--ETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            G        GQRG     G+   + +    G  G S    PP   GPP L G
Sbjct: 956  GQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAG 1007



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 49/148 (33%), Positives = 57/148 (38%), Gaps = 22/148 (14%)

Query: 101 GEAGTPA-PRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--AADGSP---HVSTSPTPA 154
           G AG P  P A     P+G   PPG +G +G   +PG  G   A G P    V   P PA
Sbjct: 404 GIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPA 463

Query: 155 PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGM--ET 210
            G  G R AR  P PT    P        R  P  R      G  G +GPA   G     
Sbjct: 464 -GEEGKRGARGEPGPTGLPGP-----PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPA 517

Query: 211 QKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
             +   G+ GR      P  AG P  +G
Sbjct: 518 GPKGSPGEAGR------PGEAGLPGAKG 539



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 50/171 (29%), Positives = 59/171 (34%), Gaps = 31/171 (18%)

Query: 89  GIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA-------- 140
           G+   P P    G  G P    A+  A  GA   PG +G  G    PGE GA        
Sbjct: 686 GVQGPPGPAGPRGANGAPGNDGAKGDA--GAPGAPGSQGAPGLQGMPGERGAAGLPGPKG 743

Query: 141 ---------ADGSPHVS-----TSPTPAPGRRGGREARLRPMPTPSWIPVSSH-KKAARS 185
                    ADGSP        T P   PG  G    +    P+    P  +      R 
Sbjct: 744 DRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG 803

Query: 186 EPAERRPSLLQGGQRGPAHSTGMETQK-EAFD-GQGGRSPLPLPPSTAGPP 234
           EP    P+    G  GP  + G    K E  D G  G +  P P   AGPP
Sbjct: 804 EPGPPGPA----GFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP 850



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 46/154 (29%), Positives = 56/154 (36%), Gaps = 24/154 (15%)

Query: 101 GEAGTPAPRAARLG-APRGASPPPGEEGRAGAWRSPGEAGA-ADGSPHVSTSPTPAPGRR 158
           G  G P P  AR      GA+ PPG  G AG    PG  GA  +  P     P  + G +
Sbjct: 311 GRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ---GPRGSEGPQ 367

Query: 159 GGREARLRPMPT----PSWIPVSSHKKAARSE------------PAERRPSLLQ--GGQR 200
           G R     P P     P+  P +  +  A+              P  R PS  Q  GG  
Sbjct: 368 GVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPP 427

Query: 201 GPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPP 234
           GP  ++G E       G  G    P P    GPP
Sbjct: 428 GPKGNSG-EPGAPGSKGDTGAKGEPGPVGVQGPP 460



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 44/158 (27%), Positives = 52/158 (32%), Gaps = 26/158 (16%)

Query: 89  GIWRDPAPVMSHG-----EAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADG 143
           G+  + AP +S+G       G   P       PRG   PPG  G  G    PGE G    
Sbjct: 154 GLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGA 213

Query: 144 S-PHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQR 200
           S P     P   PG+ G      +P                   P ER P   QG  G  
Sbjct: 214 SGPMGPRGPPGPPGKNGDDGEAGKP-----------------GRPGERGPPGPQGARGLP 256

Query: 201 GPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G A   GM+  +  F G  G      P    G P   G
Sbjct: 257 GTAGLPGMKGHR-GFSGLDGAKGDAGPAGPKGEPGSPG 293



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 41/144 (28%), Positives = 50/144 (34%), Gaps = 20/144 (13%)

Query: 101 GEAGTPA----PRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPG 156
           GE G P     P A  +  P+G +   G  G AG   SPGEAG               PG
Sbjct: 485 GERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAG--------RPGEAGLPG 536

Query: 157 RRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAF- 215
            +G   +   P P     P     +  R  P          G RG A   G    K A  
Sbjct: 537 AKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPG------PPGARGQAGVMGFPGPKGAAG 590

Query: 216 -DGQGGRSPLPLPPSTAGPPPLEG 238
             G+ G   +P PP   GP   +G
Sbjct: 591 EPGKAGERGVPGPPGAVGPAGKDG 614



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 44/155 (28%), Positives = 53/155 (34%), Gaps = 32/155 (20%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG-----------------AADG 143
           G  G   PR      PRG + PPG +G  G    PG  G                  + G
Sbjct: 112 GPKGDTGPRG-----PRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYG 166

Query: 144 SPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPA 203
               ST     PG  G   +  R +P P   P     +    EP E   S    G RGP 
Sbjct: 167 YDEKSTGGISVPGPMG--PSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPM-GPRGPP 223

Query: 204 HSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
              G    K   DG+ G+   P  P   GPP  +G
Sbjct: 224 GPPG----KNGDDGEAGK---PGRPGERGPPGPQG 251



 Score = 32.0 bits (71), Expect = 0.48
 Identities = 25/72 (34%), Positives = 31/72 (43%), Gaps = 16/72 (22%)

Query: 88   AGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHV 147
            +G+   P P  S GE G           P GAS P G  G  G+  +PG+ G  +G P  
Sbjct: 1114 SGLQGPPGPPGSPGEQG-----------PSGASGPAGPRGPPGSAGAPGKDG-LNGLP-- 1159

Query: 148  STSPTPAPGRRG 159
               P   PG RG
Sbjct: 1160 --GPIGPPGPRG 1169


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
           sapiens]
          Length = 1818

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 40/129 (31%), Positives = 51/129 (39%), Gaps = 15/129 (11%)

Query: 116 PRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPA-PGRRGGREARLRPMPTPSWI 174
           PRG   P G +GRAG    PG +G A     +     P  PGR+G + +   P       
Sbjct: 818 PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP-----GF 872

Query: 175 PVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGME-----TQKEAFDGQGGRSPLPLPPS 229
           P ++ +K AR    +  P     GQRGP    G       T K    G  G    P PP 
Sbjct: 873 PGANGEKGARGVAGKPGPR----GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG 928

Query: 230 TAGPPPLEG 238
             GP   +G
Sbjct: 929 ERGPQGPQG 937



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 53/196 (27%), Positives = 65/196 (33%), Gaps = 44/196 (22%)

Query: 80   GAGRVVRLAGIWRDPAPVMSHGEAGTPAP--------RAARLGA--------------PR 117
            G G VV   G   +  P+   G  G P P         A + GA              P 
Sbjct: 976  GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1035

Query: 118  GASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREAR----LRPMPTPSW 173
            G    PGE G  GA  +PG  G     P     P  +PG RG         L   P P  
Sbjct: 1036 GLRGFPGERGLPGAQGAPGLKGGE--GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1093

Query: 174  IPVSSHKKAARSEPAERRPSLLQG--------GQRGPAHSTGMETQK--------EAFDG 217
             P  + +K A  E   + P+   G        G  GPA S G +  K        +   G
Sbjct: 1094 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1153

Query: 218  QGGRSPLPLPPSTAGP 233
              G +  P PP   GP
Sbjct: 1154 DKGENGPPGPPGLQGP 1169



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 20/167 (11%)

Query: 82   GRVVRLAGIWRDPAPVMSHGEAGTPAPRA-ARLGAPRGASPPPGEEGRAGAWRSPGEAG- 139
            G V  + G+     P    GEAG P P   A +G P+G     GE G  GA   PG  G 
Sbjct: 1255 GSVGSVGGVGEKGEP----GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP 1310

Query: 140  AADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-- 197
              D  P  +  P   PG  G         P P+        K    +P +  P    G  
Sbjct: 1311 PGDDGPKGNPGPVGFPGDPGPPGE-----PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1365

Query: 198  ------GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                  G+RGP  + G E  ++   G  G +    PP   GP   +G
Sbjct: 1366 GPPGPPGKRGPPGAAGAE-GRQGEKGAKGEAGAEGPPGKTGPVGPQG 1411



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 45/164 (27%), Positives = 60/164 (36%), Gaps = 18/164 (10%)

Query: 85   VRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAA--D 142
            + L G+   P     +G+ G   P       PRG   P G +G  G   S G  G     
Sbjct: 1209 IGLQGLPGPPGEKGENGDVGPMGPPGPP--GPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266

Query: 143  GSPHVSTSPTPAPGRRG-GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG---- 197
            G P  + +P P PG  G G     R     +  P ++    A+  P +  P    G    
Sbjct: 1267 GEPGEAGNPGP-PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1325

Query: 198  -------GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPP 234
                   G+ GPA   G+   K   DG  G+   P P   AGPP
Sbjct: 1326 PGDPGPPGEPGPAGQDGVGGDK-GEDGDPGQPGPPGPSGEAGPP 1368



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 40/139 (28%), Positives = 52/139 (37%), Gaps = 18/139 (12%)

Query: 101  GEAGTPAPRAARLG--APRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRR 158
            G+ G P P    +G   P G + P GE G  G    PGE G    +        P P   
Sbjct: 970  GKTGPPGPGGV-VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1028

Query: 159  GGRE--ARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-GQRGPAHSTGMETQKEAF 215
             G++  A LR  P    +P            A+  P L  G G +GP    G   ++ + 
Sbjct: 1029 SGKDGPAGLRGFPGERGLP-----------GAQGAPGLKGGEGPQGPPGPVGSPGERGS- 1076

Query: 216  DGQGGRSPLPLPPSTAGPP 234
             G  G   LP  P   GPP
Sbjct: 1077 AGTAGPIGLPGRPGPQGPP 1095



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 46/163 (28%), Positives = 54/163 (33%), Gaps = 32/163 (19%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSP-- 151
           P    + GE+G P P+      PRG   PPG  G+ G    PG    ADG   +   P  
Sbjct: 558 PGSSGAKGESGDPGPQG-----PRGVQGPPGPTGKPGKRGRPG----ADGGRGMPGEPGA 608

Query: 152 ---------TPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG----- 197
                       PG +G R  R      P   P        R E  E  P  L G     
Sbjct: 609 KGDRGFDGLPGLPGDKGHRGER-----GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR 663

Query: 198 GQRGPAHSTGMETQ--KEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G  GP  + G   Q      DG  G      P    GPP  +G
Sbjct: 664 GLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG 706



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 43/165 (26%), Positives = 57/165 (34%), Gaps = 21/165 (12%)

Query: 94   PAPVMSHGEAGTPAPRAAR----------LGAPRGASPPPGEEGRAGAWRSPGEAG---- 139
            P P  + G  G P P   R             P+G   PPG++G  G     GE G    
Sbjct: 912  PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 971

Query: 140  AADGSPHVSTSPTPAPGRRGGREARLRP----MPTPSWIPVSSHKKAARSEPAERRPSLL 195
                 P     P    G  G    R  P     P    +P ++ K+ A+ +P  +  S  
Sbjct: 972  TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1031

Query: 196  QG--GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
             G  G RG     G+   + A   +GG  P   PP   G P   G
Sbjct: 1032 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG-PPGPVGSPGERG 1075



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 49/162 (30%), Positives = 57/162 (35%), Gaps = 27/162 (16%)

Query: 94   PAPVMSHGEAGTPAPRAARLG-----APRGASPPPGEEGRAGAWRSPGEAGAADGSPHVS 148
            P PV S GE G+ A  A  +G      P+G   P GE+G  G     G AG  DG     
Sbjct: 1065 PGPVGSPGERGS-AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG-RDGVQGPV 1122

Query: 149  TSPTPA-PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG---------- 197
              P PA P    G +     +  P         K  + E     P  LQG          
Sbjct: 1123 GLPGPAGPAGSPGEDGDKGEIGEPG----QKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1178

Query: 198  -GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
             G+ GP    GM  QK    G  G    P PP   G   L G
Sbjct: 1179 DGEPGPRGQQGMFGQK----GDEGARGFPGPPGPIGLQGLPG 1216



 Score = 35.8 bits (81), Expect = 0.033
 Identities = 48/148 (32%), Positives = 54/148 (36%), Gaps = 28/148 (18%)

Query: 94   PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTP 153
            P PV   GE G P   AA    P G   PPG  G  G   S GE G     P +     P
Sbjct: 1425 PGPV---GEQGLPG--AAGQDGPPGPMGPPGLPGLKGDPGSKGEKG----HPGLIGLIGP 1475

Query: 154  APGRRGGREARLRPMPTPS-------WIPVSSHKKAARSEPAERRPSLLQGGQRGPAHST 206
             PG +G +  R  P    S        IP  +        P    P     G +G   ST
Sbjct: 1476 -PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQ----GPKGNKGST 1530

Query: 207  GMETQKEAFDGQGGRSPLPLPPSTAGPP 234
            G         GQ G S LP PP + GPP
Sbjct: 1531 GPA-------GQKGDSGLPGPPGSPGPP 1551



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 48/173 (27%)

Query: 104 GTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--------AADGSPHVSTSPTPAP 155
           G P P       P G   PPG +G  G    PG+ G         ADG P    +    P
Sbjct: 454 GPPGP-----AGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 508

Query: 156 GRRGG-------------------REARLR------PM-----PTPSWIPVSSHKKAARS 185
            R GG                   ++AR+       PM     P P   P SS  K    
Sbjct: 509 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 568

Query: 186 EPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           +P  + P     G +GP   TG   ++      GGR  +P  P   G    +G
Sbjct: 569 DPGPQGPR----GVQGPPGPTGKPGKRGRPGADGGRG-MPGEPGAKGDRGFDG 616



 Score = 31.6 bits (70), Expect = 0.63
 Identities = 34/131 (25%), Positives = 47/131 (35%), Gaps = 20/131 (15%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
           G  G P P+      P+G   PPG++G  G    PG  G           P   PG +G 
Sbjct: 682 GVDGPPGPKGNM--GPQGEPGPPGQQGNPGPQGLPGPQG-----------PIGPPGEKGP 728

Query: 161 R-EARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMETQKEA 214
           + +  L  +P     P    K+    E     P   QG     G RG   + G+   K +
Sbjct: 729 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 788

Query: 215 FDGQGGRSPLP 225
             G+ G    P
Sbjct: 789 -KGEKGEDGFP 798



 Score = 28.9 bits (63), Expect = 4.1
 Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 10/74 (13%)

Query: 96  PVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA--ADGSP-------- 145
           P +S  EA   A       A RG   P G  GR G    PG +GA    G P        
Sbjct: 519 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 578

Query: 146 HVSTSPTPAPGRRG 159
                PT  PG+RG
Sbjct: 579 QGPPGPTGKPGKRG 592



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 19/59 (32%), Positives = 24/59 (40%), Gaps = 4/59 (6%)

Query: 180 KKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           +K  + EPA   P +L  G  GPA   G+        G  G +  P  P   GPP   G
Sbjct: 436 EKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP----PGLQGPTGPPGDPGDRGPPGRPG 490


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
           sapiens]
          Length = 1767

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 40/129 (31%), Positives = 51/129 (39%), Gaps = 15/129 (11%)

Query: 116 PRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPA-PGRRGGREARLRPMPTPSWI 174
           PRG   P G +GRAG    PG +G A     +     P  PGR+G + +   P       
Sbjct: 767 PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP-----GF 821

Query: 175 PVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGME-----TQKEAFDGQGGRSPLPLPPS 229
           P ++ +K AR    +  P     GQRGP    G       T K    G  G    P PP 
Sbjct: 822 PGANGEKGARGVAGKPGPR----GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG 877

Query: 230 TAGPPPLEG 238
             GP   +G
Sbjct: 878 ERGPQGPQG 886



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 53/196 (27%), Positives = 65/196 (33%), Gaps = 44/196 (22%)

Query: 80   GAGRVVRLAGIWRDPAPVMSHGEAGTPAP--------RAARLGA--------------PR 117
            G G VV   G   +  P+   G  G P P         A + GA              P 
Sbjct: 925  GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 984

Query: 118  GASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREAR----LRPMPTPSW 173
            G    PGE G  GA  +PG  G     P     P  +PG RG         L   P P  
Sbjct: 985  GLRGFPGERGLPGAQGAPGLKGGE--GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1042

Query: 174  IPVSSHKKAARSEPAERRPSLLQG--------GQRGPAHSTGMETQK--------EAFDG 217
             P  + +K A  E   + P+   G        G  GPA S G +  K        +   G
Sbjct: 1043 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1102

Query: 218  QGGRSPLPLPPSTAGP 233
              G +  P PP   GP
Sbjct: 1103 DKGENGPPGPPGLQGP 1118



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 20/167 (11%)

Query: 82   GRVVRLAGIWRDPAPVMSHGEAGTPAPRA-ARLGAPRGASPPPGEEGRAGAWRSPGEAG- 139
            G V  + G+     P    GEAG P P   A +G P+G     GE G  GA   PG  G 
Sbjct: 1204 GSVGSVGGVGEKGEP----GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP 1259

Query: 140  AADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-- 197
              D  P  +  P   PG  G         P P+        K    +P +  P    G  
Sbjct: 1260 PGDDGPKGNPGPVGFPGDPGPPGE-----PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1314

Query: 198  ------GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                  G+RGP  + G E  ++   G  G +    PP   GP   +G
Sbjct: 1315 GPPGPPGKRGPPGAAGAE-GRQGEKGAKGEAGAEGPPGKTGPVGPQG 1360



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 45/164 (27%), Positives = 60/164 (36%), Gaps = 18/164 (10%)

Query: 85   VRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAA--D 142
            + L G+   P     +G+ G   P       PRG   P G +G  G   S G  G     
Sbjct: 1158 IGLQGLPGPPGEKGENGDVGPMGPPGPP--GPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215

Query: 143  GSPHVSTSPTPAPGRRG-GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG---- 197
            G P  + +P P PG  G G     R     +  P ++    A+  P +  P    G    
Sbjct: 1216 GEPGEAGNPGP-PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1274

Query: 198  -------GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPP 234
                   G+ GPA   G+   K   DG  G+   P P   AGPP
Sbjct: 1275 PGDPGPPGEPGPAGQDGVGGDK-GEDGDPGQPGPPGPSGEAGPP 1317



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 40/139 (28%), Positives = 52/139 (37%), Gaps = 18/139 (12%)

Query: 101  GEAGTPAPRAARLG--APRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRR 158
            G+ G P P    +G   P G + P GE G  G    PGE G    +        P P   
Sbjct: 919  GKTGPPGPGGV-VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 977

Query: 159  GGRE--ARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-GQRGPAHSTGMETQKEAF 215
             G++  A LR  P    +P            A+  P L  G G +GP    G   ++ + 
Sbjct: 978  SGKDGPAGLRGFPGERGLP-----------GAQGAPGLKGGEGPQGPPGPVGSPGERGS- 1025

Query: 216  DGQGGRSPLPLPPSTAGPP 234
             G  G   LP  P   GPP
Sbjct: 1026 AGTAGPIGLPGRPGPQGPP 1044



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 46/163 (28%), Positives = 54/163 (33%), Gaps = 32/163 (19%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSP-- 151
           P    + GE+G P P+      PRG   PPG  G+ G    PG    ADG   +   P  
Sbjct: 507 PGSSGAKGESGDPGPQG-----PRGVQGPPGPTGKPGKRGRPG----ADGGRGMPGEPGA 557

Query: 152 ---------TPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG----- 197
                       PG +G R  R      P   P        R E  E  P  L G     
Sbjct: 558 KGDRGFDGLPGLPGDKGHRGER-----GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR 612

Query: 198 GQRGPAHSTGMETQ--KEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G  GP  + G   Q      DG  G      P    GPP  +G
Sbjct: 613 GLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG 655



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 43/165 (26%), Positives = 57/165 (34%), Gaps = 21/165 (12%)

Query: 94   PAPVMSHGEAGTPAPRAAR----------LGAPRGASPPPGEEGRAGAWRSPGEAG---- 139
            P P  + G  G P P   R             P+G   PPG++G  G     GE G    
Sbjct: 861  PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 920

Query: 140  AADGSPHVSTSPTPAPGRRGGREARLRP----MPTPSWIPVSSHKKAARSEPAERRPSLL 195
                 P     P    G  G    R  P     P    +P ++ K+ A+ +P  +  S  
Sbjct: 921  TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 980

Query: 196  QG--GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
             G  G RG     G+   + A   +GG  P   PP   G P   G
Sbjct: 981  DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG-PPGPVGSPGERG 1024



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 49/162 (30%), Positives = 57/162 (35%), Gaps = 27/162 (16%)

Query: 94   PAPVMSHGEAGTPAPRAARLG-----APRGASPPPGEEGRAGAWRSPGEAGAADGSPHVS 148
            P PV S GE G+ A  A  +G      P+G   P GE+G  G     G AG  DG     
Sbjct: 1014 PGPVGSPGERGS-AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG-RDGVQGPV 1071

Query: 149  TSPTPA-PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG---------- 197
              P PA P    G +     +  P         K  + E     P  LQG          
Sbjct: 1072 GLPGPAGPAGSPGEDGDKGEIGEPG----QKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1127

Query: 198  -GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
             G+ GP    GM  QK    G  G    P PP   G   L G
Sbjct: 1128 DGEPGPRGQQGMFGQK----GDEGARGFPGPPGPIGLQGLPG 1165



 Score = 35.8 bits (81), Expect = 0.033
 Identities = 48/148 (32%), Positives = 54/148 (36%), Gaps = 28/148 (18%)

Query: 94   PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTP 153
            P PV   GE G P   AA    P G   PPG  G  G   S GE G     P +     P
Sbjct: 1374 PGPV---GEQGLPG--AAGQDGPPGPMGPPGLPGLKGDPGSKGEKG----HPGLIGLIGP 1424

Query: 154  APGRRGGREARLRPMPTPS-------WIPVSSHKKAARSEPAERRPSLLQGGQRGPAHST 206
             PG +G +  R  P    S        IP  +        P    P     G +G   ST
Sbjct: 1425 -PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQ----GPKGNKGST 1479

Query: 207  GMETQKEAFDGQGGRSPLPLPPSTAGPP 234
            G         GQ G S LP PP + GPP
Sbjct: 1480 GPA-------GQKGDSGLPGPPGSPGPP 1500



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 48/173 (27%)

Query: 104 GTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--------AADGSPHVSTSPTPAP 155
           G P P       P G   PPG +G  G    PG+ G         ADG P    +    P
Sbjct: 403 GPPGP-----AGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 457

Query: 156 GRRGG-------------------REARLR------PM-----PTPSWIPVSSHKKAARS 185
            R GG                   ++AR+       PM     P P   P SS  K    
Sbjct: 458 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 517

Query: 186 EPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           +P  + P     G +GP   TG   ++      GGR  +P  P   G    +G
Sbjct: 518 DPGPQGPR----GVQGPPGPTGKPGKRGRPGADGGRG-MPGEPGAKGDRGFDG 565



 Score = 31.6 bits (70), Expect = 0.63
 Identities = 34/131 (25%), Positives = 47/131 (35%), Gaps = 20/131 (15%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
           G  G P P+      P+G   PPG++G  G    PG  G           P   PG +G 
Sbjct: 631 GVDGPPGPKGNM--GPQGEPGPPGQQGNPGPQGLPGPQG-----------PIGPPGEKGP 677

Query: 161 R-EARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMETQKEA 214
           + +  L  +P     P    K+    E     P   QG     G RG   + G+   K +
Sbjct: 678 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737

Query: 215 FDGQGGRSPLP 225
             G+ G    P
Sbjct: 738 -KGEKGEDGFP 747



 Score = 28.9 bits (63), Expect = 4.1
 Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 10/74 (13%)

Query: 96  PVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA--ADGSP-------- 145
           P +S  EA   A       A RG   P G  GR G    PG +GA    G P        
Sbjct: 468 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 527

Query: 146 HVSTSPTPAPGRRG 159
                PT  PG+RG
Sbjct: 528 QGPPGPTGKPGKRG 541



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 19/59 (32%), Positives = 24/59 (40%), Gaps = 4/59 (6%)

Query: 180 KKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           +K  + EPA   P +L  G  GPA   G+        G  G +  P  P   GPP   G
Sbjct: 385 EKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP----PGLQGPTGPPGDPGDRGPPGRPG 439


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
           sapiens]
          Length = 1806

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 40/129 (31%), Positives = 51/129 (39%), Gaps = 15/129 (11%)

Query: 116 PRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPA-PGRRGGREARLRPMPTPSWI 174
           PRG   P G +GRAG    PG +G A     +     P  PGR+G + +   P       
Sbjct: 806 PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP-----GF 860

Query: 175 PVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGME-----TQKEAFDGQGGRSPLPLPPS 229
           P ++ +K AR    +  P     GQRGP    G       T K    G  G    P PP 
Sbjct: 861 PGANGEKGARGVAGKPGPR----GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG 916

Query: 230 TAGPPPLEG 238
             GP   +G
Sbjct: 917 ERGPQGPQG 925



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 53/196 (27%), Positives = 65/196 (33%), Gaps = 44/196 (22%)

Query: 80   GAGRVVRLAGIWRDPAPVMSHGEAGTPAP--------RAARLGA--------------PR 117
            G G VV   G   +  P+   G  G P P         A + GA              P 
Sbjct: 964  GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1023

Query: 118  GASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREAR----LRPMPTPSW 173
            G    PGE G  GA  +PG  G     P     P  +PG RG         L   P P  
Sbjct: 1024 GLRGFPGERGLPGAQGAPGLKGGE--GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1081

Query: 174  IPVSSHKKAARSEPAERRPSLLQG--------GQRGPAHSTGMETQK--------EAFDG 217
             P  + +K A  E   + P+   G        G  GPA S G +  K        +   G
Sbjct: 1082 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1141

Query: 218  QGGRSPLPLPPSTAGP 233
              G +  P PP   GP
Sbjct: 1142 DKGENGPPGPPGLQGP 1157



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 20/167 (11%)

Query: 82   GRVVRLAGIWRDPAPVMSHGEAGTPAPRA-ARLGAPRGASPPPGEEGRAGAWRSPGEAG- 139
            G V  + G+     P    GEAG P P   A +G P+G     GE G  GA   PG  G 
Sbjct: 1243 GSVGSVGGVGEKGEP----GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP 1298

Query: 140  AADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-- 197
              D  P  +  P   PG  G         P P+        K    +P +  P    G  
Sbjct: 1299 PGDDGPKGNPGPVGFPGDPGPPGE-----PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA 1353

Query: 198  ------GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                  G+RGP  + G E  ++   G  G +    PP   GP   +G
Sbjct: 1354 GPPGPPGKRGPPGAAGAE-GRQGEKGAKGEAGAEGPPGKTGPVGPQG 1399



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 45/164 (27%), Positives = 60/164 (36%), Gaps = 18/164 (10%)

Query: 85   VRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAA--D 142
            + L G+   P     +G+ G   P       PRG   P G +G  G   S G  G     
Sbjct: 1197 IGLQGLPGPPGEKGENGDVGPMGPPGPP--GPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254

Query: 143  GSPHVSTSPTPAPGRRG-GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG---- 197
            G P  + +P P PG  G G     R     +  P ++    A+  P +  P    G    
Sbjct: 1255 GEPGEAGNPGP-PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1313

Query: 198  -------GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPP 234
                   G+ GPA   G+   K   DG  G+   P P   AGPP
Sbjct: 1314 PGDPGPPGEPGPAGQDGVGGDK-GEDGDPGQPGPPGPSGEAGPP 1356



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 40/139 (28%), Positives = 52/139 (37%), Gaps = 18/139 (12%)

Query: 101  GEAGTPAPRAARLG--APRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRR 158
            G+ G P P    +G   P G + P GE G  G    PGE G    +        P P   
Sbjct: 958  GKTGPPGPGGV-VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1016

Query: 159  GGRE--ARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-GQRGPAHSTGMETQKEAF 215
             G++  A LR  P    +P            A+  P L  G G +GP    G   ++ + 
Sbjct: 1017 SGKDGPAGLRGFPGERGLP-----------GAQGAPGLKGGEGPQGPPGPVGSPGERGS- 1064

Query: 216  DGQGGRSPLPLPPSTAGPP 234
             G  G   LP  P   GPP
Sbjct: 1065 AGTAGPIGLPGRPGPQGPP 1083



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 46/163 (28%), Positives = 54/163 (33%), Gaps = 32/163 (19%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSP-- 151
           P    + GE+G P P+      PRG   PPG  G+ G    PG    ADG   +   P  
Sbjct: 546 PGSSGAKGESGDPGPQG-----PRGVQGPPGPTGKPGKRGRPG----ADGGRGMPGEPGA 596

Query: 152 ---------TPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG----- 197
                       PG +G R  R      P   P        R E  E  P  L G     
Sbjct: 597 KGDRGFDGLPGLPGDKGHRGER-----GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR 651

Query: 198 GQRGPAHSTGMETQ--KEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G  GP  + G   Q      DG  G      P    GPP  +G
Sbjct: 652 GLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG 694



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 43/165 (26%), Positives = 57/165 (34%), Gaps = 21/165 (12%)

Query: 94   PAPVMSHGEAGTPAPRAAR----------LGAPRGASPPPGEEGRAGAWRSPGEAG---- 139
            P P  + G  G P P   R             P+G   PPG++G  G     GE G    
Sbjct: 900  PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 959

Query: 140  AADGSPHVSTSPTPAPGRRGGREARLRP----MPTPSWIPVSSHKKAARSEPAERRPSLL 195
                 P     P    G  G    R  P     P    +P ++ K+ A+ +P  +  S  
Sbjct: 960  TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1019

Query: 196  QG--GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
             G  G RG     G+   + A   +GG  P   PP   G P   G
Sbjct: 1020 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG-PPGPVGSPGERG 1063



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 49/162 (30%), Positives = 57/162 (35%), Gaps = 27/162 (16%)

Query: 94   PAPVMSHGEAGTPAPRAARLG-----APRGASPPPGEEGRAGAWRSPGEAGAADGSPHVS 148
            P PV S GE G+ A  A  +G      P+G   P GE+G  G     G AG  DG     
Sbjct: 1053 PGPVGSPGERGS-AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG-RDGVQGPV 1110

Query: 149  TSPTPA-PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG---------- 197
              P PA P    G +     +  P         K  + E     P  LQG          
Sbjct: 1111 GLPGPAGPAGSPGEDGDKGEIGEPG----QKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1166

Query: 198  -GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
             G+ GP    GM  QK    G  G    P PP   G   L G
Sbjct: 1167 DGEPGPRGQQGMFGQK----GDEGARGFPGPPGPIGLQGLPG 1204



 Score = 35.8 bits (81), Expect = 0.033
 Identities = 48/148 (32%), Positives = 54/148 (36%), Gaps = 28/148 (18%)

Query: 94   PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTP 153
            P PV   GE G P   AA    P G   PPG  G  G   S GE G     P +     P
Sbjct: 1413 PGPV---GEQGLPG--AAGQDGPPGPMGPPGLPGLKGDPGSKGEKG----HPGLIGLIGP 1463

Query: 154  APGRRGGREARLRPMPTPS-------WIPVSSHKKAARSEPAERRPSLLQGGQRGPAHST 206
             PG +G +  R  P    S        IP  +        P    P     G +G   ST
Sbjct: 1464 -PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQ----GPKGNKGST 1518

Query: 207  GMETQKEAFDGQGGRSPLPLPPSTAGPP 234
            G         GQ G S LP PP + GPP
Sbjct: 1519 GPA-------GQKGDSGLPGPPGSPGPP 1539



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 48/173 (27%)

Query: 104 GTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--------AADGSPHVSTSPTPAP 155
           G P P       P G   PPG +G  G    PG+ G         ADG P    +    P
Sbjct: 442 GPPGP-----AGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 496

Query: 156 GRRGG-------------------REARLR------PM-----PTPSWIPVSSHKKAARS 185
            R GG                   ++AR+       PM     P P   P SS  K    
Sbjct: 497 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 556

Query: 186 EPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           +P  + P     G +GP   TG   ++      GGR  +P  P   G    +G
Sbjct: 557 DPGPQGPR----GVQGPPGPTGKPGKRGRPGADGGRG-MPGEPGAKGDRGFDG 604



 Score = 31.6 bits (70), Expect = 0.63
 Identities = 34/131 (25%), Positives = 47/131 (35%), Gaps = 20/131 (15%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
           G  G P P+      P+G   PPG++G  G    PG  G           P   PG +G 
Sbjct: 670 GVDGPPGPKGNM--GPQGEPGPPGQQGNPGPQGLPGPQG-----------PIGPPGEKGP 716

Query: 161 R-EARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMETQKEA 214
           + +  L  +P     P    K+    E     P   QG     G RG   + G+   K +
Sbjct: 717 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776

Query: 215 FDGQGGRSPLP 225
             G+ G    P
Sbjct: 777 -KGEKGEDGFP 786



 Score = 28.9 bits (63), Expect = 4.1
 Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 10/74 (13%)

Query: 96  PVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA--ADGSP-------- 145
           P +S  EA   A       A RG   P G  GR G    PG +GA    G P        
Sbjct: 507 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 566

Query: 146 HVSTSPTPAPGRRG 159
                PT  PG+RG
Sbjct: 567 QGPPGPTGKPGKRG 580



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 19/59 (32%), Positives = 24/59 (40%), Gaps = 4/59 (6%)

Query: 180 KKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           +K  + EPA   P +L  G  GPA   G+        G  G +  P  P   GPP   G
Sbjct: 424 EKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP----PGLQGPTGPPGDPGDRGPPGRPG 478


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 47/156 (30%), Positives = 53/156 (33%), Gaps = 22/156 (14%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTP------- 153
            GE G P         PRG   PPG  G +G    PG AGA   +P     P P       
Sbjct: 1210 GERGDPGSPGISPPGPRGKKGPPGPPGSSG---PPGPAGATGRAPKDIPDPGPPGDQGPP 1266

Query: 154  -------APGRRG--GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGP 202
                   APG  G  G    LR  P    +P           P  +      G  GQ+GP
Sbjct: 1267 GPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGP 1326

Query: 203  AHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                G +     F G  G   LP PP   GP  L G
Sbjct: 1327 VGFPGPQ-GPHGFPGPPGEKGLPGPPGRKGPTGLPG 1361



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 46/163 (28%), Positives = 58/163 (35%), Gaps = 34/163 (20%)

Query: 94   PAPVMSHGEAGTPAPRAARLGAPR-----GASPPPGEEGRAGAWRSPGEAGAADGSPHVS 148
            P P    G  G P P+  R G P      G    PG EG  GA   PGE G +       
Sbjct: 890  PGPFGDDGLPGPPGPKGPR-GLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSG------ 942

Query: 149  TSPTPAPGRRG--GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAH 204
                  PG RG  G +  + P      + + S K      P E  P    G  G+RG   
Sbjct: 943  -----LPGDRGLRGAKGAIGPPGDEGEMAIISQK----GTPGEPGPPGDDGFPGERGDKG 993

Query: 205  STGMETQKEA---------FDGQGGRSPLPLPPSTAGPPPLEG 238
            + GM+ ++             G+ G    P PP   GPP   G
Sbjct: 994  TPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTG 1036



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 41/146 (28%), Positives = 51/146 (34%), Gaps = 24/146 (16%)

Query: 93   DPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPT 152
            DP P    G+ G P P   +   P G+    G  G  G   + G +G  D  P     P 
Sbjct: 1149 DPGPRGLQGDPGIPGPPGIK--GPSGSPGLNGLHGLKGQKGTKGASGLHDVGP---PGPV 1203

Query: 153  PAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQK 212
              PG +G R     P  +P   P    KK     P          G  GPA +TG   + 
Sbjct: 1204 GIPGLKGERGDPGSPGISP---PGPRGKKGPPGPPG-------SSGPPGPAGATGRAPKD 1253

Query: 213  EAFDGQGGRSPLPLPPSTAGPPPLEG 238
                      P P PP   GPP  +G
Sbjct: 1254 ---------IPDPGPPGDQGPPGPDG 1270



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 45/162 (27%), Positives = 60/162 (37%), Gaps = 24/162 (14%)

Query: 94   PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAA--DGSPHVSTSP 151
            P P    G  G   P+  + G P     PPG +G  G+   PG  GA+   G P +   P
Sbjct: 1056 PGPPGFSGIDGARGPKGNK-GDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQ-GP 1113

Query: 152  TPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAER---RPSLLQG--------GQR 200
              +PGR G   +       P   P        R +P E     P  LQG        G +
Sbjct: 1114 RGSPGRPGPPGS-----SGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIK 1168

Query: 201  GPAHSTGMETQKEAFDGQGGRSPLPL----PPSTAGPPPLEG 238
            GP+ S G+         +G +    L    PP   G P L+G
Sbjct: 1169 GPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKG 1210



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 34/134 (25%), Positives = 43/134 (32%), Gaps = 11/134 (8%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
            G+ GT          P G    PG +G  G    PG  G +   P     P   PG  G 
Sbjct: 1184 GQKGTKGASGLHDVGPPGPVGIPGLKGERG---DPGSPGISPPGPRGKKGPPGPPGSSG- 1239

Query: 161  REARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGG 220
                    P P+     + K      P   +      G RG     G+    +   G+ G
Sbjct: 1240 -------PPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPG 1292

Query: 221  RSPLPLPPSTAGPP 234
               LP PP   GPP
Sbjct: 1293 DCGLPGPPGPPGPP 1306



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 51/168 (30%), Positives = 58/168 (34%), Gaps = 37/168 (22%)

Query: 101 GEAGTPAPRAARLGAP----RGASPPPGEEGRAGAWRSPGEAG------AADGSPHVSTS 150
           G+ G P P    LG P     G   PPG +G  G    PGEAG      +A G P    S
Sbjct: 382 GDVGPPGPPGL-LGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGS 440

Query: 151 PTPAPGRRGGREARLRPMPTPSWI------PVSSHKKAARSEPAERRPSLLQG------- 197
           P   PG  G     L+ +P  S I      P     K     P  R P   +G       
Sbjct: 441 P-GLPGAPG-----LQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCAC 494

Query: 198 -----GQRGPAHSTGMETQKE--AFDGQGGRSPLPLPPSTAGPPPLEG 238
                G  GP    G +  K      G  G    P PP   GPP L G
Sbjct: 495 EPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPG 542



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 47/172 (27%), Positives = 61/172 (35%), Gaps = 32/172 (18%)

Query: 93  DPAPVMSHGEAGTPAPRAAR--------LGA-----PRGASPPPGEEGRAGAWRSPGEAG 139
           +P P+   G  G P  + ++        LG      P GA  PPG  G+ GA   PG  G
Sbjct: 495 EPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKG 554

Query: 140 AADGSPHVS-----------TSPTPAPGRRG--GREARLRPMPTPSWIPVSSHKKAARSE 186
            A G   VS             P   PG+ G  GR+        P   P   H+ A    
Sbjct: 555 -AKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPG--PPGDHEDATPGG 611

Query: 187 PAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                P L   G+ GP    G+        G+ G   +P  P   GP  L+G
Sbjct: 612 KGFPGP-LGPPGKAGPVGPPGLGFPGP--PGERGHPGVPGHPGVRGPDGLKG 660



 Score = 32.7 bits (73), Expect = 0.28
 Identities = 47/159 (29%), Positives = 54/159 (33%), Gaps = 19/159 (11%)

Query: 96  PVMSHGEAGTPA-PRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPA 154
           P    G AG P  P        RGA   PG+ G  G   SPG  G   G P     P PA
Sbjct: 808 PKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPG-GKGQPGDVGPPGPA 866

Query: 155 PGRRG-----GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAH 204
            G +G     GR     P   P  IP           P  + P  L G     G+RG   
Sbjct: 867 -GMKGLPGLPGRPGAHGPPGLPG-IPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPG 924

Query: 205 STGM-----ETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           + G      E  ++   G  G   L       GPP  EG
Sbjct: 925 AEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEG 963



 Score = 32.0 bits (71), Expect = 0.48
 Identities = 39/139 (28%), Positives = 55/139 (39%), Gaps = 19/139 (13%)

Query: 116 PRGASPPPGEEGRAGAWRSPGEAGA-----ADGSPHVSTSPTPAPGRRG-------GREA 163
           P G   PPG +G  G   +PG +G+       G+P  +  P P PG RG       G E 
Sbjct: 678 PPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGP-PGFRGDMGDPGFGGEK 736

Query: 164 RLRPM--PTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGR 221
              P+  P P   P  + +K    +PA     L   G+RG +   G++  +      G  
Sbjct: 737 GSSPVGPPGPPGSPGVNGQKGIPGDPAFGH--LGPPGKRGLSGVPGIKGPRGDPGCPGAE 794

Query: 222 SPLPLPP--STAGPPPLEG 238
            P  +P      GP   EG
Sbjct: 795 GPAGIPGFLGLKGPKGREG 813



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 42/148 (28%), Positives = 51/148 (34%), Gaps = 25/148 (16%)

Query: 101  GEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAGA------ADGSPHVSTSPTP 153
            G  G P P+       P G    PG  GR G    PG  G        D  P +   P  
Sbjct: 1325 GPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLP-G 1383

Query: 154  APGRRGGREARLRP-MPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMET 210
            APG RG   A   P M  PS           + EP       + G  G  GP    G +T
Sbjct: 1384 APGMRGPEGAMGLPGMRGPS-------GPGCKGEPGLDGRRGVDGVPGSPGPPGRKG-DT 1435

Query: 211  QKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
             ++ + G  G      PP   G P  +G
Sbjct: 1436 GEDGYPGGPG------PPGPIGDPGPKG 1457



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 19/68 (27%), Positives = 25/68 (36%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTP 153
           P P    G+ G P     +  +P G   PPG  G  G    PG+       P      + 
Sbjct: 718 PGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSG 777

Query: 154 APGRRGGR 161
            PG +G R
Sbjct: 778 VPGIKGPR 785



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 41/152 (26%), Positives = 55/152 (36%), Gaps = 12/152 (7%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTP 153
           P P  + G +G+   +  R G P G +  PG  G  G    PG  G    SP     P  
Sbjct: 691 PGPQGAPGLSGSDGHKG-RPGTP-GTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPG 748

Query: 154 APGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQ 211
           +PG  G +     P       P    K+     P  + P    G  G  GPA   G    
Sbjct: 749 SPGVNGQKGIPGDPAFGHLGPP---GKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGL 805

Query: 212 K--EAFDGQGGRSPLPLPPSTA---GPPPLEG 238
           K  +  +G  G   +P PP  +   G P + G
Sbjct: 806 KGPKGREGHAGFPGVPGPPGHSCERGAPGIPG 837



 Score = 28.5 bits (62), Expect = 5.3
 Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 6/69 (8%)

Query: 96  PVMSHGEAGTPAPRAARLGAPRGASPP---PGEEGRAGAWRSPGEAGAA--DGSPHVSTS 150
           P+   GE G        LGA +G       PG  G  G+W + G AG     G P +   
Sbjct: 162 PLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGL-VG 220

Query: 151 PTPAPGRRG 159
           P   PGR G
Sbjct: 221 PPGQPGRPG 229



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 2/48 (4%)

Query: 101 GEAGTPA-PRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHV 147
           G+ G P  P +   G P G +  PGE G  G    PG  G   G+P V
Sbjct: 190 GDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPG-LKGNPGV 236



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 31/138 (22%), Positives = 43/138 (31%), Gaps = 33/138 (23%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
           G  G P P    +  P     PPG+ G  G +   G+ G           P    GR G 
Sbjct: 347 GNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVG--------PPGPPGLLGRPGE 398

Query: 161 REARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGG 220
             A +   P P   P                      G  G     G+  + ++  G+ G
Sbjct: 399 ACAGMIGPPGPQGFP----------------------GLPGLPGEAGIPGRPDSAPGKPG 436

Query: 221 RSPLPLPPSTAGPPPLEG 238
           +   P  P   G P L+G
Sbjct: 437 K---PGSPGLPGAPGLQG 451


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 56/162 (34%), Positives = 67/162 (41%), Gaps = 30/162 (18%)

Query: 92   RDPAP--VMSHGEAGTPAPRAARLG-APRGASPPPGEEGRA----GAWRSPGEAGAAD-- 142
            R PAP  V+S    G  AP    LG AP+  +  PG E RA    GA R+PG AG  D  
Sbjct: 1083 RAPAPSAVVSSRNGGETAP--GPLGPAPKNGTLEPGTERRAPETGGAPRAPG-AGRLDLG 1139

Query: 143  --GSPHVSTSPTPAPGRRGGREARL------RPMPTPSWIPVSSHKKAARSEPA--ERRP 192
              G   V T   P  G   G +A+       RP P P  +P     +  R EPA    RP
Sbjct: 1140 SGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARP 1199

Query: 193  SLLQGGQRG-PAHSTGMETQKEAFDGQGGRSPLPLPPSTAGP 233
             +   G+ G P    G +T   A  G G     P  P   GP
Sbjct: 1200 EVAPEGEPGAPDSRAGGDT---ALSGDGD----PPKPERKGP 1234



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 35/135 (25%), Positives = 48/135 (35%), Gaps = 21/135 (15%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
           G   T A   A +   RG +P   EE       SPGE  ++ G           P RRG 
Sbjct: 645 GAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGG---------GPSRRG- 694

Query: 161 REARLRPMPTPSWIPVSSHKKAARSEPAERRPSLL-QGGQRGPAHSTGMETQKEAFDGQG 219
                 P+P     P+ S + A    P ER  ++   GG          E        +G
Sbjct: 695 ------PLP----CPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERG 744

Query: 220 GRSPLPLPPSTAGPP 234
             + LP+ P  + PP
Sbjct: 745 SLADLPMAPPASAPP 759


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 46/160 (28%), Positives = 58/160 (36%), Gaps = 26/160 (16%)

Query: 79  LGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEA 138
           +GA       G+  +P P  S GE+G      +    P+G   P GEEG+ G     GEA
Sbjct: 333 VGAAGATGARGLVGEPGPAGSKGESGNKGEPGS--AGPQGPPGPSGEEGKRG---PNGEA 387

Query: 139 GAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGG 198
           G+A         P   PG RG         P    +P +  +      P  R  S    G
Sbjct: 388 GSA--------GPPGPPGLRGS--------PGSRGLPGADGRAGVMGPPGSRGAS-GPAG 430

Query: 199 QRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            RGP    G    +    G  G   LP  P   GP   EG
Sbjct: 431 VRGPNGDAG----RPGEPGLMGPRGLPGSPGNIGPAGKEG 466



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 48/158 (30%), Positives = 57/158 (36%), Gaps = 16/158 (10%)

Query: 88  AGIWRDPAPVMSHGEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPH 146
           AG    P P    G  G P P     L  PRG   P G  G  GA   PG AG    S  
Sbjct: 792 AGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGE 851

Query: 147 VSTS-PTPAPGRRGGREARLRPMPTPSWIPVSSHKK---AARSEPAERRPSLLQG--GQR 200
             T+ P   PG +G     L   P    +P S  ++          E  P  + G  G R
Sbjct: 852 AGTAGPPGTPGPQG-----LLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGAR 906

Query: 201 GPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           GP  + G      A  G+ GR      P   GPP  +G
Sbjct: 907 GPPGAVGSPGVNGA-PGEAGRDG---NPGNDGPPGRDG 940



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 46/158 (29%), Positives = 58/158 (36%), Gaps = 15/158 (9%)

Query: 79   LGAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEA 138
            LGA  ++ L G   +       G  G P P    +  P GA  PPG  G  G   +PGEA
Sbjct: 867  LGAPGILGLPGSRGERGLPGVAGAVGEPGPLG--IAGPPGARGPPGAVGSPGVNGAPGEA 924

Query: 139  GAADGSPHVSTSP--TPAPGRRGGR---------EARLRPMPTPSWIPVSSHKKAARSEP 187
            G  DG+P     P     PG +G R          A   P P     P   H     + P
Sbjct: 925  G-RDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGP 983

Query: 188  AERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLP 225
            +         G RGP+   G+   K    G+ G   LP
Sbjct: 984  SGPVGPAGAVGPRGPSGPQGIRGDK-GEPGEKGPRGLP 1020



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 47/162 (29%), Positives = 59/162 (36%), Gaps = 32/162 (19%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--------AADGSPHVSTSPT 152
           GE G   P       P GA+  PG +G  GA    GE G         A G    +  P 
Sbjct: 715 GEVGPAGPNG--FAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG 772

Query: 153 PA--------PGRRG--GREARLRPMPTPSWI------PVSSHKKAARSEPAERRPSLLQ 196
           PA        PG  G  G   R  P P PS I      P  + K+  R    ++ P + +
Sbjct: 773 PAGSRGDGGPPGMTGFPGAAGRTGP-PGPSGISGPPGPPGPAGKEGLRGPRGDQGP-VGR 830

Query: 197 GGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            G+ G     G   +K    G  G +    PP T GP  L G
Sbjct: 831 TGEVGAVGPPGFAGEK----GPSGEAGTAGPPGTPGPQGLLG 868



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 42/153 (27%), Positives = 50/153 (32%), Gaps = 28/153 (18%)

Query: 96  PVMSHGEAGTPAPR----------AARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSP 145
           P+ S G +G P P           A     P G S  PGE G AG     GE G      
Sbjct: 605 PIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRG 664

Query: 146 HVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHS 205
            +       PGR G R A     P     P  +     R E     P+    G  GP  S
Sbjct: 665 EIGN-----PGRDGARGA-----PGAVGAPGPAGATGDRGEAGAAGPA----GPAGPRGS 710

Query: 206 TGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            G   +     G  G +    P   AG P  +G
Sbjct: 711 PGERGEV----GPAGPNGFAGPAGAAGQPGAKG 739



 Score = 35.8 bits (81), Expect = 0.033
 Identities = 26/76 (34%), Positives = 29/76 (38%), Gaps = 21/76 (27%)

Query: 100 HGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAA--------DGSPHV---- 147
           HGE G P P       PRG   PPGE G AG     G  G +         G P V    
Sbjct: 576 HGEFGLPGP-----AGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAV 630

Query: 148 ----STSPTPAPGRRG 159
                + P+  PG RG
Sbjct: 631 GTAGPSGPSGLPGERG 646



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 44/162 (27%), Positives = 58/162 (35%), Gaps = 31/162 (19%)

Query: 87  LAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPH 146
           LAG    P P  ++G  G P P+  + G  +G   PPG  G  G    PG +G A     
Sbjct: 515 LAGARGAPGPDGNNGAQGPPGPQGVQGG--KGEQGPPGPPGFQGL---PGPSGPA----- 564

Query: 147 VSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAH 204
                   PG RG        +     +P  +  +  R  P E   +   G  G RGP+ 
Sbjct: 565 ---GEVGKPGERG--------LHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSG 613

Query: 205 STGMETQK--------EAFDGQGGRSPLPLPPSTAGPPPLEG 238
             G +  K            G  G S LP     AG P  +G
Sbjct: 614 PPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKG 655



 Score = 35.0 bits (79), Expect = 0.057
 Identities = 43/156 (27%), Positives = 50/156 (32%), Gaps = 34/156 (21%)

Query: 96   PVMSHGEAGTPAPRA----ARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSP 151
            P   HG  G   P      A    PRG S P G  G  G    PGE G           P
Sbjct: 971  PAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKG---EPGEKG-----------P 1016

Query: 152  TPAPGRRGGREARLRP--------MPTPSWI-PVSSHKKAARSEPAERRPSLLQGGQRGP 202
               PG +G    +  P           P  + P      A  S PA +       G  GP
Sbjct: 1017 RGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGP 1076

Query: 203  AHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            A   G +       G  G +  P PP   GPP + G
Sbjct: 1077 AGIRGPQ-------GHQGPAGPPGPPGPPGPPGVSG 1105



 Score = 34.3 bits (77), Expect = 0.097
 Identities = 49/164 (29%), Positives = 57/164 (34%), Gaps = 35/164 (21%)

Query: 87  LAGIWRDPAPVMSHGEAGTPAPRAARLGAP--RGASPPPGEEGRAGAWRSPGEAGA--AD 142
           L G+   P      GE G P       G P   GA   PGE GR GA   PG AGA  +D
Sbjct: 185 LDGLKGQPGAPGVKGEPGAPGEN----GTPGQTGARGLPGERGRVGA---PGPAGARGSD 237

Query: 143 GS--------PHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSL 194
           GS        P  S  P   PG  G +              + +   A  + PA  R  +
Sbjct: 238 GSVGPVGPAGPIGSAGPPGFPGAPGPKG------------EIGAVGNAGPAGPAGPRGEV 285

Query: 195 LQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
              G  GP    G         G  G + L   P  AG P L G
Sbjct: 286 GLPGLSGPVGPPG-NPGANGLTGAKGAAGL---PGVAGAPGLPG 325



 Score = 32.7 bits (73), Expect = 0.28
 Identities = 42/152 (27%), Positives = 47/152 (30%), Gaps = 32/152 (21%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG------------AADGSPHVS 148
           G AG   PR  R     G   PPG +G  G    PG  G            A      V 
Sbjct: 33  GPAGDRGPRGER-----GPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVG 87

Query: 149 TSPTP--APGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHST 206
             P P    G RG   A   P P     P     +  ++ PA         G RGPA   
Sbjct: 88  LGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPA---------GARGPAGPP 138

Query: 207 GMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G    K   DG  G+   P      GP    G
Sbjct: 139 G----KAGEDGHPGKPGRPGERGVVGPQGARG 166



 Score = 32.0 bits (71), Expect = 0.48
 Identities = 41/148 (27%), Positives = 50/148 (33%), Gaps = 17/148 (11%)

Query: 94  PAPVMSHGEAGTPAPRA-ARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPT 152
           P P    G+ G    +  A L   RGA   PG +G  GA   PG  G   G       P 
Sbjct: 495 PGPKGPTGDPGKNGDKGHAGLAGARGA---PGPDGNNGAQGPPGPQGVQGGKG--EQGPP 549

Query: 153 PAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMET 210
             PG +G        +P PS       K   R    E       G  G+RGP   +G   
Sbjct: 550 GPPGFQG--------LPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAG 601

Query: 211 QKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                  +G   P P P    G P + G
Sbjct: 602 PTGPIGSRGPSGP-PGPDGNKGEPGVVG 628



 Score = 31.2 bits (69), Expect = 0.82
 Identities = 24/74 (32%), Positives = 27/74 (36%), Gaps = 3/74 (4%)

Query: 89  GIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVS 148
           G+   P P+   G  G P   AA    P+G   P GE G  G     G  G A       
Sbjct: 85  GVGLGPGPMGLMGPRGPPG--AAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAG 142

Query: 149 TSPTPA-PGRRGGR 161
               P  PGR G R
Sbjct: 143 EDGHPGKPGRPGER 156



 Score = 29.3 bits (64), Expect = 3.1
 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 12/63 (19%)

Query: 177 SSHKKAARSEPA-ERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPP 235
           S  ++  R  PA +R P     G+RGP    G        DG+ G +  P PP   GPP 
Sbjct: 24  SLQEETVRKGPAGDRGPR----GERGPPGPPGR-------DGEDGPTGPPGPPGPPGPPG 72

Query: 236 LEG 238
           L G
Sbjct: 73  LGG 75



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 35/142 (24%), Positives = 46/142 (32%), Gaps = 19/142 (13%)

Query: 101 GEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRG 159
           G AG   P  +R    P G   P G+ GR G     G  G      ++  +    P    
Sbjct: 412 GRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLP 471

Query: 160 GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQG 219
           G + R  P+              AR EP     ++   G +GP    G    K    G  
Sbjct: 472 GIDGRPGPI----------GPAGARGEPG----NIGFPGPKGPTGDPGKNGDK-GHAGLA 516

Query: 220 GRSPLPLPP---STAGPPPLEG 238
           G    P P       GPP  +G
Sbjct: 517 GARGAPGPDGNNGAQGPPGPQG 538


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 45/160 (28%), Positives = 56/160 (35%), Gaps = 21/160 (13%)

Query: 90  IWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHV-- 147
           I R+  P         P P   R  A   A PPP    R G    P  +   D +P +  
Sbjct: 277 IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQ 336

Query: 148 -------STSPTPAPGRRGGREARLRPMPTP--SWIPVSSHKKAARSEPAERRPSLLQGG 198
                  ST P P+PGR G       P+P P     P        RS P    P + + G
Sbjct: 337 RNLSLSSSTPPLPSPGRSG-------PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNG 389

Query: 199 QRGPA-HSTGMETQKEAFDG--QGGRSPLPLPPSTAGPPP 235
               A  +T     +   D    G R PLP    +AG PP
Sbjct: 390 STSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPP 429



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 44/179 (24%), Positives = 58/179 (32%), Gaps = 36/179 (20%)

Query: 94  PAPVMS--HGEAGTPAPRAARLGAPRGASPP-PGEEGRAGAWRSPGEAGAADGSPHVSTS 150
           P P+ S  H     P P   R  +P    PP PG  G A    S  ++  +  SP  +  
Sbjct: 191 PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRP 250

Query: 151 PTPAPGRRG------------------GREARLRPMPTPSWIPVSSHKKAARSE------ 186
           P P    R                    REA   P P  +  PV S  + + S       
Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP 310

Query: 187 --PAERRPSLLQGGQRG-------PAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPL 236
             P+   P  L     G       P  +  + +        G   PLP PPS   PPP+
Sbjct: 311 PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPV 369


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 45/160 (28%), Positives = 56/160 (35%), Gaps = 21/160 (13%)

Query: 90  IWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHV-- 147
           I R+  P         P P   R  A   A PPP    R G    P  +   D +P +  
Sbjct: 277 IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQ 336

Query: 148 -------STSPTPAPGRRGGREARLRPMPTP--SWIPVSSHKKAARSEPAERRPSLLQGG 198
                  ST P P+PGR G       P+P P     P        RS P    P + + G
Sbjct: 337 RNLSLSSSTPPLPSPGRSG-------PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNG 389

Query: 199 QRGPA-HSTGMETQKEAFDG--QGGRSPLPLPPSTAGPPP 235
               A  +T     +   D    G R PLP    +AG PP
Sbjct: 390 STSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPP 429



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 44/179 (24%), Positives = 58/179 (32%), Gaps = 36/179 (20%)

Query: 94  PAPVMS--HGEAGTPAPRAARLGAPRGASPP-PGEEGRAGAWRSPGEAGAADGSPHVSTS 150
           P P+ S  H     P P   R  +P    PP PG  G A    S  ++  +  SP  +  
Sbjct: 191 PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRP 250

Query: 151 PTPAPGRRG------------------GREARLRPMPTPSWIPVSSHKKAARSE------ 186
           P P    R                    REA   P P  +  PV S  + + S       
Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP 310

Query: 187 --PAERRPSLLQGGQRG-------PAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPL 236
             P+   P  L     G       P  +  + +        G   PLP PPS   PPP+
Sbjct: 311 PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPV 369


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 46/153 (30%), Positives = 58/153 (37%), Gaps = 25/153 (16%)

Query: 101 GEAGTPAPRAARLGAP--RGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPA-PGR 157
           G+ G    R   +G P  RG   P G +GR G    PG  G       +     P  PGR
Sbjct: 662 GDIGVKGDRG-EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 720

Query: 158 RGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMETQK 212
           +G + +   P       P +S +K AR    +  P   +G     GQRGP  +TG    K
Sbjct: 721 QGPKGSLGFP-----GFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK 775

Query: 213 EAFDGQGGRSP-----LPLP------PSTAGPP 234
               G G   P     LP P      P   GPP
Sbjct: 776 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 808



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 43/148 (29%), Positives = 56/148 (37%), Gaps = 28/148 (18%)

Query: 101 GEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAG-----AADGSPHVSTSPTPA 154
           GE G P P+       P+G   PPG++G  G     GE G        G P V   P  A
Sbjct: 788 GERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV-VGPQGA 846

Query: 155 PGRRGGREARLRP----MPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMET 210
            G  G    R  P     P    +P ++ K+  + +P          G+ GPA   G   
Sbjct: 847 AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP----GKDGPAGLRG--- 899

Query: 211 QKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
               F G+ G       P TAG P L+G
Sbjct: 900 ----FPGERGL------PGTAGGPGLKG 917



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 42/143 (29%), Positives = 54/143 (37%), Gaps = 18/143 (12%)

Query: 101 GEAGTPAPRAARLGAPRGASP---PPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGR 157
           G+ G P P    +  P+GA+    P GE G  G    PGE G    +    T   P P  
Sbjct: 830 GKTGPPGPPG--VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 887

Query: 158 RGGRE--ARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAF 215
             G++  A LR  P    +P ++     +       PS    G  GPA S G    +   
Sbjct: 888 APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG---PS----GPPGPAGSPG----ERGA 936

Query: 216 DGQGGRSPLPLPPSTAGPPPLEG 238
            G GG    P  P   GPP   G
Sbjct: 937 AGSGGPIGPPGRPGPQGPPGAAG 959



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 36/118 (30%), Positives = 45/118 (38%), Gaps = 14/118 (11%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTP 153
           P P    G  G   P+ + LG P+G   PPG++G  G    PG  GA    PH    P  
Sbjct: 535 PGPPGVRGMDGPQGPKGS-LG-PQGEPGPPGQQGTPGTQGLPGPQGAI--GPHGEKGPQG 590

Query: 154 APGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGME 209
            PG  G        MP     P    K+        + PS  QG  G  GP    G++
Sbjct: 591 KPGLPG--------MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 640



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 40/143 (27%), Positives = 53/143 (37%), Gaps = 9/143 (6%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
            GE G P  +  +    +G   PPG  G  G    PG AG ADG P  +  P    G +G 
Sbjct: 1001 GEVGDPGQKGTK--GNKGEHGPPGPPGPIGPVGQPGAAG-ADGEPG-ARGPQGHFGAKGD 1056

Query: 161  REAR-LRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQKEAFDG 217
               R     P P  +         + E  +  P    G  G RGPA   G +  +    G
Sbjct: 1057 EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGG 1116

Query: 218  QGGRSP--LPLPPSTAGPPPLEG 238
             G   P      P  +G P ++G
Sbjct: 1117 VGNLGPPGEKGEPGESGSPGIQG 1139



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 40/139 (28%), Positives = 47/139 (33%), Gaps = 34/139 (24%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADG-SPHVSTSPTPAPGRRG 159
            GE G P    +    P G + PPG  G+ G   SPG  G   G           APG+ G
Sbjct: 1208 GEDGEPGQPGSP--GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265

Query: 160  GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQG 219
                           PV     A +  P          G RG   S G + +  A  GQ 
Sbjct: 1266 ---------------PVGPAGPAGKPGP---------DGLRGLPGSVGQQGRPGA-TGQA 1300

Query: 220  GRSPLPLPPSTAGPPPLEG 238
            G      PP   GPP L G
Sbjct: 1301 G------PPGPVGPPGLPG 1313



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 36/138 (26%), Positives = 47/138 (34%), Gaps = 15/138 (10%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
            GE G   PR  R    +G S  PGE G  G     G+ G       V     P P   GG
Sbjct: 1139 GEPGVKGPRGER--GEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1196

Query: 161  REARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMETQKEAF 215
               +               +     +P    P+   G     G+RGPA S G E ++   
Sbjct: 1197 PRGQ-------DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1249

Query: 216  DGQGGRSPLPLPPSTAGP 233
              +G    +  P  T GP
Sbjct: 1250 GAKGDPGAIGAPGKT-GP 1266



 Score = 34.3 bits (77), Expect = 0.097
 Identities = 47/174 (27%), Positives = 56/174 (32%), Gaps = 35/174 (20%)

Query: 93  DPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGS-------- 144
           D  PV++  EA   A       A RG   P G  GR G    PG  G    S        
Sbjct: 376 DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP 435

Query: 145 --PHVSTSPTPAPGRRGGREA-RLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRG 201
             P   T P    GRRG   A   R MP    +            P E+       G RG
Sbjct: 436 RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEK-------GHRG 488

Query: 202 PAHSTGM-----ETQKEAFDGQGGRSPLP------------LPPSTAGPPPLEG 238
              + G+     E  +   DG+ G   LP             PP   GPP + G
Sbjct: 489 DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 542



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 40/144 (27%), Positives = 50/144 (34%), Gaps = 22/144 (15%)

Query: 104 GTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--------AADGSPHVSTSPTPAP 155
           G P P       P G   PPG +G  G    PGE G         +DG+P    +    P
Sbjct: 313 GPPGPEG-----PAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLP 367

Query: 156 GRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMET 210
            R G       P+         +  + AR   A R P    G     G  G   S G++ 
Sbjct: 368 FRFGSGGGDKGPVVAAQEAQAQAILQQARL--ALRGPPGPMGYTGRPGPLGQPGSPGLKG 425

Query: 211 QKEAFDGQGGRSPLPL--PPSTAG 232
           +      QG R P  L  PP  AG
Sbjct: 426 ESGDLGPQGPRGPQGLTGPPGKAG 449



 Score = 31.2 bits (69), Expect = 0.82
 Identities = 41/163 (25%), Positives = 53/163 (32%), Gaps = 9/163 (5%)

Query: 80  GAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG 139
           G   ++   GI  +P PV   GE G P     R G P G+   PG  G +        +G
Sbjct: 319 GPAGLIGPPGIQGNPGPVGDPGERGPP----GRAGLP-GSDGAPGPPGTSLMLPFRFGSG 373

Query: 140 AADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPS--LLQG 197
             D  P V+     A          LR  P P               P  +  S  L   
Sbjct: 374 GGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQ 433

Query: 198 GQRGPAHSTGM--ETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G RGP   TG   +  +    G  G   +P  P   G    +G
Sbjct: 434 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDG 476



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 53/188 (28%), Positives = 65/188 (34%), Gaps = 43/188 (22%)

Query: 89   GIWRDPAPVMSHGEAGTPAPR-AARLGAPRGASPPPGEEG---RAGAWRSPGEAG----- 139
            G+  +  P    G AG+P  R AA  G P G    PG +G    AG    PGE G     
Sbjct: 914  GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 973

Query: 140  AADGSPHVSTSPTPA-----------------PGRRG--GREARLRPMPTPSWI-PVSSH 179
              DG       P PA                 PG++G  G +    P   P  I PV   
Sbjct: 974  GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1033

Query: 180  KKA-ARSEPAERRPSLLQG--------GQRGPAHSTGME-----TQKEAFDGQGGRSPLP 225
              A A  EP  R P    G        G  GP    G++     + ++   G  G    P
Sbjct: 1034 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1093

Query: 226  LPPSTAGP 233
             PP   GP
Sbjct: 1094 GPPGPRGP 1101



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 38/146 (26%), Positives = 47/146 (32%), Gaps = 18/146 (12%)

Query: 94   PAPVMSHGEAGTPAPRAARLGA----PRGASPPPGEEGRAGAWRSPGEAGAADGSPHVST 149
            P P    G  G   P+    G     P G    PGE G  G    PG  G          
Sbjct: 1096 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1155

Query: 150  SPTPA-PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGM 208
            S  P  PG  G +       P  +  PV          P +  P     G+ GP    G 
Sbjct: 1156 SGQPGEPGPPGPKGPTGDDGPKGNPGPVGF--------PGDPGPP----GEGGPRGQDGA 1203

Query: 209  ETQKEAFDGQGGRSPLPLPPSTAGPP 234
            +  +   DG+ G+   P P    GPP
Sbjct: 1204 KGDR-GEDGEPGQPGSPGPTGENGPP 1228



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 41/138 (29%), Positives = 50/138 (36%), Gaps = 15/138 (10%)

Query: 99   SHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRR 158
            S G+ G P   A     P G   PPG  G  G   + GE     G P +     P PG +
Sbjct: 1287 SVGQQGRPG--ATGQAGPPGPVGPPGLPGLRGDAGAKGE----KGHPGLIGLIGP-PGEQ 1339

Query: 159  GGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAF--D 216
            G  E   R +P P   P    +K     P    P +  GG  G     G +  K A    
Sbjct: 1340 G--EKGDRGLPGPQGSP---GQKGEMGIPGASGP-IGPGGPPGLPGPAGPKGAKGATGPG 1393

Query: 217  GQGGRSPLPLPPSTAGPP 234
            G  G   +  PP   GPP
Sbjct: 1394 GPKGEKGVQGPPGHPGPP 1411



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 30/115 (26%), Positives = 38/115 (33%), Gaps = 14/115 (12%)

Query: 94   PAPVMSHGEAGTPAPRAAR--LGAPR--GASPPPGEEGRAGAWRSPGEAGAADGSPHVST 149
            P PV   G  G      A+   G P   G   PPGE+G  G    PG  G+      +  
Sbjct: 1303 PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGI 1362

Query: 150  SPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAH 204
                 P   GG          P  +P  +  K A+       P   +G Q  P H
Sbjct: 1363 PGASGPIGPGG----------PPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1407



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 16/51 (31%), Positives = 21/51 (41%), Gaps = 2/51 (3%)

Query: 89   GIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG 139
            GI     P+   G  G P P   +    +GA+ P G +G  G    PG  G
Sbjct: 1361 GIPGASGPIGPGGPPGLPGPAGPK--GAKGATGPGGPKGEKGVQGPPGHPG 1409


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 46/153 (30%), Positives = 58/153 (37%), Gaps = 25/153 (16%)

Query: 101 GEAGTPAPRAARLGAP--RGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPA-PGR 157
           G+ G    R   +G P  RG   P G +GR G    PG  G       +     P  PGR
Sbjct: 641 GDIGVKGDRG-EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 699

Query: 158 RGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMETQK 212
           +G + +   P       P +S +K AR    +  P   +G     GQRGP  +TG    K
Sbjct: 700 QGPKGSLGFP-----GFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK 754

Query: 213 EAFDGQGGRSP-----LPLP------PSTAGPP 234
               G G   P     LP P      P   GPP
Sbjct: 755 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 787



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 43/148 (29%), Positives = 56/148 (37%), Gaps = 28/148 (18%)

Query: 101 GEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAG-----AADGSPHVSTSPTPA 154
           GE G P P+       P+G   PPG++G  G     GE G        G P V   P  A
Sbjct: 767 GERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV-VGPQGA 825

Query: 155 PGRRGGREARLRP----MPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMET 210
            G  G    R  P     P    +P ++ K+  + +P          G+ GPA   G   
Sbjct: 826 AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP----GKDGPAGLRG--- 878

Query: 211 QKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
               F G+ G       P TAG P L+G
Sbjct: 879 ----FPGERGL------PGTAGGPGLKG 896



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 42/143 (29%), Positives = 54/143 (37%), Gaps = 18/143 (12%)

Query: 101 GEAGTPAPRAARLGAPRGASP---PPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGR 157
           G+ G P P    +  P+GA+    P GE G  G    PGE G    +    T   P P  
Sbjct: 809 GKTGPPGPPG--VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 866

Query: 158 RGGRE--ARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAF 215
             G++  A LR  P    +P ++     +       PS    G  GPA S G    +   
Sbjct: 867 APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG---PS----GPPGPAGSPG----ERGA 915

Query: 216 DGQGGRSPLPLPPSTAGPPPLEG 238
            G GG    P  P   GPP   G
Sbjct: 916 AGSGGPIGPPGRPGPQGPPGAAG 938



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 36/118 (30%), Positives = 45/118 (38%), Gaps = 14/118 (11%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTP 153
           P P    G  G   P+ + LG P+G   PPG++G  G    PG  GA    PH    P  
Sbjct: 514 PGPPGVRGMDGPQGPKGS-LG-PQGEPGPPGQQGTPGTQGLPGPQGAI--GPHGEKGPQG 569

Query: 154 APGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGME 209
            PG  G        MP     P    K+        + PS  QG  G  GP    G++
Sbjct: 570 KPGLPG--------MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 619



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 40/143 (27%), Positives = 53/143 (37%), Gaps = 9/143 (6%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
            GE G P  +  +    +G   PPG  G  G    PG AG ADG P  +  P    G +G 
Sbjct: 980  GEVGDPGQKGTK--GNKGEHGPPGPPGPIGPVGQPGAAG-ADGEPG-ARGPQGHFGAKGD 1035

Query: 161  REAR-LRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQKEAFDG 217
               R     P P  +         + E  +  P    G  G RGPA   G +  +    G
Sbjct: 1036 EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGG 1095

Query: 218  QGGRSP--LPLPPSTAGPPPLEG 238
             G   P      P  +G P ++G
Sbjct: 1096 VGNLGPPGEKGEPGESGSPGIQG 1118



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 40/139 (28%), Positives = 47/139 (33%), Gaps = 34/139 (24%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADG-SPHVSTSPTPAPGRRG 159
            GE G P    +    P G + PPG  G+ G   SPG  G   G           APG+ G
Sbjct: 1187 GEDGEPGQPGSP--GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1244

Query: 160  GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQG 219
                           PV     A +  P          G RG   S G + +  A  GQ 
Sbjct: 1245 ---------------PVGPAGPAGKPGP---------DGLRGLPGSVGQQGRPGA-TGQA 1279

Query: 220  GRSPLPLPPSTAGPPPLEG 238
            G      PP   GPP L G
Sbjct: 1280 G------PPGPVGPPGLPG 1292



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 36/138 (26%), Positives = 47/138 (34%), Gaps = 15/138 (10%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
            GE G   PR  R    +G S  PGE G  G     G+ G       V     P P   GG
Sbjct: 1118 GEPGVKGPRGER--GEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1175

Query: 161  REARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMETQKEAF 215
               +               +     +P    P+   G     G+RGPA S G E ++   
Sbjct: 1176 PRGQ-------DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1228

Query: 216  DGQGGRSPLPLPPSTAGP 233
              +G    +  P  T GP
Sbjct: 1229 GAKGDPGAIGAPGKT-GP 1245



 Score = 34.3 bits (77), Expect = 0.097
 Identities = 47/174 (27%), Positives = 56/174 (32%), Gaps = 35/174 (20%)

Query: 93  DPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGS-------- 144
           D  PV++  EA   A       A RG   P G  GR G    PG  G    S        
Sbjct: 355 DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP 414

Query: 145 --PHVSTSPTPAPGRRGGREA-RLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRG 201
             P   T P    GRRG   A   R MP    +            P E+       G RG
Sbjct: 415 RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEK-------GHRG 467

Query: 202 PAHSTGM-----ETQKEAFDGQGGRSPLP------------LPPSTAGPPPLEG 238
              + G+     E  +   DG+ G   LP             PP   GPP + G
Sbjct: 468 DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 521



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 40/144 (27%), Positives = 50/144 (34%), Gaps = 22/144 (15%)

Query: 104 GTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--------AADGSPHVSTSPTPAP 155
           G P P       P G   PPG +G  G    PGE G         +DG+P    +    P
Sbjct: 292 GPPGPEG-----PAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLP 346

Query: 156 GRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMET 210
            R G       P+         +  + AR   A R P    G     G  G   S G++ 
Sbjct: 347 FRFGSGGGDKGPVVAAQEAQAQAILQQARL--ALRGPPGPMGYTGRPGPLGQPGSPGLKG 404

Query: 211 QKEAFDGQGGRSPLPL--PPSTAG 232
           +      QG R P  L  PP  AG
Sbjct: 405 ESGDLGPQGPRGPQGLTGPPGKAG 428



 Score = 31.2 bits (69), Expect = 0.82
 Identities = 41/163 (25%), Positives = 53/163 (32%), Gaps = 9/163 (5%)

Query: 80  GAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG 139
           G   ++   GI  +P PV   GE G P     R G P G+   PG  G +        +G
Sbjct: 298 GPAGLIGPPGIQGNPGPVGDPGERGPP----GRAGLP-GSDGAPGPPGTSLMLPFRFGSG 352

Query: 140 AADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPS--LLQG 197
             D  P V+     A          LR  P P               P  +  S  L   
Sbjct: 353 GGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQ 412

Query: 198 GQRGPAHSTGM--ETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G RGP   TG   +  +    G  G   +P  P   G    +G
Sbjct: 413 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDG 455



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 53/188 (28%), Positives = 65/188 (34%), Gaps = 43/188 (22%)

Query: 89   GIWRDPAPVMSHGEAGTPAPR-AARLGAPRGASPPPGEEG---RAGAWRSPGEAG----- 139
            G+  +  P    G AG+P  R AA  G P G    PG +G    AG    PGE G     
Sbjct: 893  GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 952

Query: 140  AADGSPHVSTSPTPA-----------------PGRRG--GREARLRPMPTPSWI-PVSSH 179
              DG       P PA                 PG++G  G +    P   P  I PV   
Sbjct: 953  GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1012

Query: 180  KKA-ARSEPAERRPSLLQG--------GQRGPAHSTGME-----TQKEAFDGQGGRSPLP 225
              A A  EP  R P    G        G  GP    G++     + ++   G  G    P
Sbjct: 1013 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1072

Query: 226  LPPSTAGP 233
             PP   GP
Sbjct: 1073 GPPGPRGP 1080



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 38/146 (26%), Positives = 47/146 (32%), Gaps = 18/146 (12%)

Query: 94   PAPVMSHGEAGTPAPRAARLGA----PRGASPPPGEEGRAGAWRSPGEAGAADGSPHVST 149
            P P    G  G   P+    G     P G    PGE G  G    PG  G          
Sbjct: 1075 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1134

Query: 150  SPTPA-PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGM 208
            S  P  PG  G +       P  +  PV          P +  P     G+ GP    G 
Sbjct: 1135 SGQPGEPGPPGPKGPTGDDGPKGNPGPVGF--------PGDPGPP----GEGGPRGQDGA 1182

Query: 209  ETQKEAFDGQGGRSPLPLPPSTAGPP 234
            +  +   DG+ G+   P P    GPP
Sbjct: 1183 KGDR-GEDGEPGQPGSPGPTGENGPP 1207



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 41/138 (29%), Positives = 50/138 (36%), Gaps = 15/138 (10%)

Query: 99   SHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRR 158
            S G+ G P   A     P G   PPG  G  G   + GE     G P +     P PG +
Sbjct: 1266 SVGQQGRPG--ATGQAGPPGPVGPPGLPGLRGDAGAKGE----KGHPGLIGLIGP-PGEQ 1318

Query: 159  GGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAF--D 216
            G  E   R +P P   P    +K     P    P +  GG  G     G +  K A    
Sbjct: 1319 G--EKGDRGLPGPQGSP---GQKGEMGIPGASGP-IGPGGPPGLPGPAGPKGAKGATGPG 1372

Query: 217  GQGGRSPLPLPPSTAGPP 234
            G  G   +  PP   GPP
Sbjct: 1373 GPKGEKGVQGPPGHPGPP 1390



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 30/115 (26%), Positives = 38/115 (33%), Gaps = 14/115 (12%)

Query: 94   PAPVMSHGEAGTPAPRAAR--LGAPR--GASPPPGEEGRAGAWRSPGEAGAADGSPHVST 149
            P PV   G  G      A+   G P   G   PPGE+G  G    PG  G+      +  
Sbjct: 1282 PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGI 1341

Query: 150  SPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAH 204
                 P   GG          P  +P  +  K A+       P   +G Q  P H
Sbjct: 1342 PGASGPIGPGG----------PPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1386



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 16/51 (31%), Positives = 21/51 (41%), Gaps = 2/51 (3%)

Query: 89   GIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG 139
            GI     P+   G  G P P   +    +GA+ P G +G  G    PG  G
Sbjct: 1340 GIPGASGPIGPGGPPGLPGPAGPK--GAKGATGPGGPKGEKGVQGPPGHPG 1388


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
           [Homo sapiens]
          Length = 1736

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 46/153 (30%), Positives = 58/153 (37%), Gaps = 25/153 (16%)

Query: 101 GEAGTPAPRAARLGAP--RGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPA-PGR 157
           G+ G    R   +G P  RG   P G +GR G    PG  G       +     P  PGR
Sbjct: 748 GDIGVKGDRG-EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 806

Query: 158 RGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMETQK 212
           +G + +   P       P +S +K AR    +  P   +G     GQRGP  +TG    K
Sbjct: 807 QGPKGSLGFP-----GFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK 861

Query: 213 EAFDGQGGRSP-----LPLP------PSTAGPP 234
               G G   P     LP P      P   GPP
Sbjct: 862 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 894



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 43/148 (29%), Positives = 56/148 (37%), Gaps = 28/148 (18%)

Query: 101  GEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAG-----AADGSPHVSTSPTPA 154
            GE G P P+       P+G   PPG++G  G     GE G        G P V   P  A
Sbjct: 874  GERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV-VGPQGA 932

Query: 155  PGRRGGREARLRP----MPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMET 210
             G  G    R  P     P    +P ++ K+  + +P          G+ GPA   G   
Sbjct: 933  AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP----GKDGPAGLRG--- 985

Query: 211  QKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                F G+ G       P TAG P L+G
Sbjct: 986  ----FPGERGL------PGTAGGPGLKG 1003



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 42/143 (29%), Positives = 54/143 (37%), Gaps = 18/143 (12%)

Query: 101  GEAGTPAPRAARLGAPRGASP---PPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGR 157
            G+ G P P    +  P+GA+    P GE G  G    PGE G    +    T   P P  
Sbjct: 916  GKTGPPGPPG--VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 973

Query: 158  RGGRE--ARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAF 215
              G++  A LR  P    +P ++     +       PS    G  GPA S G    +   
Sbjct: 974  APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG---PS----GPPGPAGSPG----ERGA 1022

Query: 216  DGQGGRSPLPLPPSTAGPPPLEG 238
             G GG    P  P   GPP   G
Sbjct: 1023 AGSGGPIGPPGRPGPQGPPGAAG 1045



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 36/118 (30%), Positives = 45/118 (38%), Gaps = 14/118 (11%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTP 153
           P P    G  G   P+ + LG P+G   PPG++G  G    PG  GA    PH    P  
Sbjct: 621 PGPPGVRGMDGPQGPKGS-LG-PQGEPGPPGQQGTPGTQGLPGPQGAI--GPHGEKGPQG 676

Query: 154 APGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGME 209
            PG  G        MP     P    K+        + PS  QG  G  GP    G++
Sbjct: 677 KPGLPG--------MPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVD 726



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 40/143 (27%), Positives = 53/143 (37%), Gaps = 9/143 (6%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
            GE G P  +  +    +G   PPG  G  G    PG AG ADG P  +  P    G +G 
Sbjct: 1087 GEVGDPGQKGTK--GNKGEHGPPGPPGPIGPVGQPGAAG-ADGEPG-ARGPQGHFGAKGD 1142

Query: 161  REAR-LRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQKEAFDG 217
               R     P P  +         + E  +  P    G  G RGPA   G +  +    G
Sbjct: 1143 EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGG 1202

Query: 218  QGGRSP--LPLPPSTAGPPPLEG 238
             G   P      P  +G P ++G
Sbjct: 1203 VGNLGPPGEKGEPGESGSPGIQG 1225



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 40/139 (28%), Positives = 47/139 (33%), Gaps = 34/139 (24%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADG-SPHVSTSPTPAPGRRG 159
            GE G P    +    P G + PPG  G+ G   SPG  G   G           APG+ G
Sbjct: 1294 GEDGEPGQPGSP--GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1351

Query: 160  GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQG 219
                           PV     A +  P          G RG   S G + +  A  GQ 
Sbjct: 1352 ---------------PVGPAGPAGKPGP---------DGLRGLPGSVGQQGRPGA-TGQA 1386

Query: 220  GRSPLPLPPSTAGPPPLEG 238
            G      PP   GPP L G
Sbjct: 1387 G------PPGPVGPPGLPG 1399



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 36/138 (26%), Positives = 47/138 (34%), Gaps = 15/138 (10%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
            GE G   PR  R    +G S  PGE G  G     G+ G       V     P P   GG
Sbjct: 1225 GEPGVKGPRGER--GEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1282

Query: 161  REARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMETQKEAF 215
               +               +     +P    P+   G     G+RGPA S G E ++   
Sbjct: 1283 PRGQ-------DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1335

Query: 216  DGQGGRSPLPLPPSTAGP 233
              +G    +  P  T GP
Sbjct: 1336 GAKGDPGAIGAPGKT-GP 1352



 Score = 34.3 bits (77), Expect = 0.097
 Identities = 47/174 (27%), Positives = 56/174 (32%), Gaps = 35/174 (20%)

Query: 93  DPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGS-------- 144
           D  PV++  EA   A       A RG   P G  GR G    PG  G    S        
Sbjct: 462 DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP 521

Query: 145 --PHVSTSPTPAPGRRGGREA-RLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRG 201
             P   T P    GRRG   A   R MP    +            P E+       G RG
Sbjct: 522 RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEK-------GHRG 574

Query: 202 PAHSTGM-----ETQKEAFDGQGGRSPLP------------LPPSTAGPPPLEG 238
              + G+     E  +   DG+ G   LP             PP   GPP + G
Sbjct: 575 DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 628



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 40/144 (27%), Positives = 50/144 (34%), Gaps = 22/144 (15%)

Query: 104 GTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--------AADGSPHVSTSPTPAP 155
           G P P       P G   PPG +G  G    PGE G         +DG+P    +    P
Sbjct: 399 GPPGPEG-----PAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLP 453

Query: 156 GRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMET 210
            R G       P+         +  + AR   A R P    G     G  G   S G++ 
Sbjct: 454 FRFGSGGGDKGPVVAAQEAQAQAILQQARL--ALRGPPGPMGYTGRPGPLGQPGSPGLKG 511

Query: 211 QKEAFDGQGGRSPLPL--PPSTAG 232
           +      QG R P  L  PP  AG
Sbjct: 512 ESGDLGPQGPRGPQGLTGPPGKAG 535



 Score = 31.2 bits (69), Expect = 0.82
 Identities = 41/163 (25%), Positives = 53/163 (32%), Gaps = 9/163 (5%)

Query: 80  GAGRVVRLAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG 139
           G   ++   GI  +P PV   GE G P     R G P G+   PG  G +        +G
Sbjct: 405 GPAGLIGPPGIQGNPGPVGDPGERGPP----GRAGLP-GSDGAPGPPGTSLMLPFRFGSG 459

Query: 140 AADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPS--LLQG 197
             D  P V+     A          LR  P P               P  +  S  L   
Sbjct: 460 GGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQ 519

Query: 198 GQRGPAHSTGM--ETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           G RGP   TG   +  +    G  G   +P  P   G    +G
Sbjct: 520 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDG 562



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 53/188 (28%), Positives = 65/188 (34%), Gaps = 43/188 (22%)

Query: 89   GIWRDPAPVMSHGEAGTPAPR-AARLGAPRGASPPPGEEG---RAGAWRSPGEAG----- 139
            G+  +  P    G AG+P  R AA  G P G    PG +G    AG    PGE G     
Sbjct: 1000 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 1059

Query: 140  AADGSPHVSTSPTPA-----------------PGRRG--GREARLRPMPTPSWI-PVSSH 179
              DG       P PA                 PG++G  G +    P   P  I PV   
Sbjct: 1060 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1119

Query: 180  KKA-ARSEPAERRPSLLQG--------GQRGPAHSTGME-----TQKEAFDGQGGRSPLP 225
              A A  EP  R P    G        G  GP    G++     + ++   G  G    P
Sbjct: 1120 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1179

Query: 226  LPPSTAGP 233
             PP   GP
Sbjct: 1180 GPPGPRGP 1187



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 38/146 (26%), Positives = 47/146 (32%), Gaps = 18/146 (12%)

Query: 94   PAPVMSHGEAGTPAPRAARLGA----PRGASPPPGEEGRAGAWRSPGEAGAADGSPHVST 149
            P P    G  G   P+    G     P G    PGE G  G    PG  G          
Sbjct: 1182 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1241

Query: 150  SPTPA-PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGM 208
            S  P  PG  G +       P  +  PV          P +  P     G+ GP    G 
Sbjct: 1242 SGQPGEPGPPGPKGPTGDDGPKGNPGPVGF--------PGDPGPP----GEGGPRGQDGA 1289

Query: 209  ETQKEAFDGQGGRSPLPLPPSTAGPP 234
            +  +   DG+ G+   P P    GPP
Sbjct: 1290 KGDR-GEDGEPGQPGSPGPTGENGPP 1314



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 41/138 (29%), Positives = 50/138 (36%), Gaps = 15/138 (10%)

Query: 99   SHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRR 158
            S G+ G P   A     P G   PPG  G  G   + GE     G P +     P PG +
Sbjct: 1373 SVGQQGRPG--ATGQAGPPGPVGPPGLPGLRGDAGAKGE----KGHPGLIGLIGP-PGEQ 1425

Query: 159  GGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAF--D 216
            G  E   R +P P   P    +K     P    P +  GG  G     G +  K A    
Sbjct: 1426 G--EKGDRGLPGPQGSP---GQKGEMGIPGASGP-IGPGGPPGLPGPAGPKGAKGATGPG 1479

Query: 217  GQGGRSPLPLPPSTAGPP 234
            G  G   +  PP   GPP
Sbjct: 1480 GPKGEKGVQGPPGHPGPP 1497



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 30/115 (26%), Positives = 38/115 (33%), Gaps = 14/115 (12%)

Query: 94   PAPVMSHGEAGTPAPRAAR--LGAPR--GASPPPGEEGRAGAWRSPGEAGAADGSPHVST 149
            P PV   G  G      A+   G P   G   PPGE+G  G    PG  G+      +  
Sbjct: 1389 PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGI 1448

Query: 150  SPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAH 204
                 P   GG          P  +P  +  K A+       P   +G Q  P H
Sbjct: 1449 PGASGPIGPGG----------PPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1493



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 16/51 (31%), Positives = 21/51 (41%), Gaps = 2/51 (3%)

Query: 89   GIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG 139
            GI     P+   G  G P P   +    +GA+ P G +G  G    PG  G
Sbjct: 1447 GIPGASGPIGPGGPPGLPGPAGPK--GAKGATGPGGPKGEKGVQGPPGHPG 1495


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 49/157 (31%), Positives = 61/157 (38%), Gaps = 23/157 (14%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAP--RGASPPPG---EEGRAGAWRSPGEAG--AADGSPH 146
           P P+   GE G    ++ + G P   G   PPG   E G+ GA   PG  G    DG+P 
Sbjct: 808 PGPLGPIGEKG----KSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPG 863

Query: 147 VSTSPTPAPGRRGGREARLRP-MPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPA 203
           +       PG +G    +  P  P P   P    K      P +R     QG  G  GPA
Sbjct: 864 I-------PGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPA 916

Query: 204 HSTGMETQKEAFDGQGGRSP--LPLPPSTAGPPPLEG 238
              G + +       G R P   P PP   G P LEG
Sbjct: 917 GVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEG 953



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 48/153 (31%), Positives = 56/153 (36%), Gaps = 34/153 (22%)

Query: 101  GEAGTPAPRAAR-----LGAPRGASPPPGEEGRAGAWRSPGEAG-----AADGSPHVSTS 150
            G+ G P    A+      G P G   PPG+ G +G   SPGE G        G P  S  
Sbjct: 1244 GKKGPPGEDGAKGSVGPTGLP-GDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGE 1302

Query: 151  P--TPAPGRRG-----GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRG 201
            P     PG+RG     GRE R               +K A+ EP    P    G  G RG
Sbjct: 1303 PGAPGPPGKRGPSGHMGREGR-------------EGEKGAKGEPGPDGPPGRTGPMGARG 1349

Query: 202  PAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPP 234
            P    G E  +    G  G   L   P   GPP
Sbjct: 1350 PPGRVGPEGLR-GIPGPVGEPGLLGAPGQMGPP 1381



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 40/143 (27%), Positives = 51/143 (35%), Gaps = 26/143 (18%)

Query: 118 GASPPPGEEGRAGAWRSPGEAGAADG-------SPHVSTSPTPAPGRRG-----GREARL 165
           G   PPGE+G  GA   PG  G A          P  S  PT  PG  G     G +  +
Sbjct: 572 GQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNV 631

Query: 166 RPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGM--------ETQKEAF 215
            P   P   P       ++  P    P  L G  G++GP  + G+               
Sbjct: 632 GPPGEPG-PPGQQGNHGSQGLPG---PQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGH 687

Query: 216 DGQGGRSPLPLPPSTAGPPPLEG 238
           +G  G      PP +AGPP   G
Sbjct: 688 EGPTGEKGAQGPPGSAGPPGYPG 710



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 53/178 (29%), Positives = 55/178 (30%), Gaps = 46/178 (25%)

Query: 89  GIWRDPAPVMSHGEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAGAA------ 141
           G+   P PV   G  G      A     PRG   P G  GR G    PG  GA       
Sbjct: 485 GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544

Query: 142 --------DGSP-------------HVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHK 180
                   DG P             HV   P P PG  G R A   P PT          
Sbjct: 545 GPKGDRGFDGLPGLPGEKGQRGDFGHVG-QPGP-PGEDGERGAEGPPGPT---------- 592

Query: 181 KAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                EP  R   LL  G RG    TG        DG  G      PP   GPP  +G
Sbjct: 593 -GQAGEPGPR--GLL--GPRGSPGPTG-RPGVTGIDGAPGAKGNVGPPGEPGPPGQQG 644



 Score = 35.0 bits (79), Expect = 0.057
 Identities = 47/184 (25%), Positives = 61/184 (33%), Gaps = 42/184 (22%)

Query: 87  LAGIWRDPAPVMSHGEAGTP-APRAARLGAPRGASPPPGEEGRAGAWRSPGEAG------ 139
           L G    P P    G  G   AP A     P G   PPG++G  G+   PG  G      
Sbjct: 603 LLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPG 662

Query: 140 --AADGSPHV-----STSPTPAPGRRG--GREARLRP--------MPTPSWIPVSSHKKA 182
                G+P +     S  P   PG  G  G +    P         P P  +  +S  + 
Sbjct: 663 EKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRG 722

Query: 183 ARSEPAERRPSLLQG--------------GQRGPAHSTGMETQKEAFDGQGGRSPLPLPP 228
            + E  E+      G              G  GP    G E  K    GQ G++    PP
Sbjct: 723 LQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPK----GQAGQAGEEGPP 778

Query: 229 STAG 232
            +AG
Sbjct: 779 GSAG 782



 Score = 35.0 bits (79), Expect = 0.057
 Identities = 42/144 (29%), Positives = 57/144 (39%), Gaps = 23/144 (15%)

Query: 101 GEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRG 159
           G+ G P PR       P+G +   GEEG  G+    G+ G   G P         PGR G
Sbjct: 749 GKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLG-VPGLPGY-------PGRPG 800

Query: 160 GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAF---- 215
            + +   P P     P+    K+ ++     +P L   G+RGP  S G   Q  A     
Sbjct: 801 PKGSIGFPGPLG---PIGEKGKSGKT----GQPGL--EGERGPPGSRGERGQPGATGQPG 851

Query: 216 -DGQGGRSPLPLPPSTAGPPPLEG 238
             G  G+   P  P   G P L+G
Sbjct: 852 PKGDVGQDGAPGIPGEKGLPGLQG 875



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 12/90 (13%)

Query: 87   LAGIWRDPAPVMSHGEAGTPAPRAARLG--APRGASPPPGEEGRAGAWRSPGEAGA-ADG 143
            L G+   P P    G+ G P P  + LG   P G + P G++G  G   SPG  G   D 
Sbjct: 1425 LPGVQGPPGP---KGDPGPPGPIGS-LGHPGPPGVAGPLGQKGSKG---SPGSMGPRGDT 1477

Query: 144  SPHVSTSPTPAPGRRGG--REARLRPMPTP 171
             P     P  AP    G  R  R  P+P P
Sbjct: 1478 GPAGPPGPPGAPAELHGLRRRRRFVPVPLP 1507



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 46/159 (28%), Positives = 58/159 (36%), Gaps = 18/159 (11%)

Query: 94   PAPVMSHGEAGT---PAPRAARLG-APRGASPPPGEEGRAGAWRSPGEAG-----AADGS 144
            P P+   G AG    P P+       P G     G  G  GA  SPGE G        G 
Sbjct: 964  PGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGL 1023

Query: 145  PHVSTS--PTPAPGRRGGREARLRPMPT-PSWIPVSSHKKAARSEPAERRPSLLQGGQRG 201
            P  S S  P    G++G R  R  P PT    IP           P    PS  + G +G
Sbjct: 1024 PGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIP---GPLGPLGPPGAAGPS-GEEGDKG 1079

Query: 202  PAHSTGMETQK--EAFDGQGGRSPLPLPPSTAGPPPLEG 238
               + G +  K  +   G  G+  +  P    GPP  +G
Sbjct: 1080 DVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADG 1118



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 44/167 (26%), Positives = 54/167 (32%), Gaps = 36/167 (21%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG-----------AADGSPHVST 149
            G+AG P     R   P G   PPG +G  G    PG  G              G P +  
Sbjct: 1094 GDAGPPGQPGIR--GPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQG 1151

Query: 150  SPTPAPGRRG--GREARLRPMPTPS--------------WIPVSSHKKAARSEPAERRPS 193
             P P PG +G  G    + P   P                +P    +  A  E  ER   
Sbjct: 1152 LPGP-PGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERG-- 1208

Query: 194  LLQGGQRGPAHSTGMETQKEAF--DGQGGRSPLPLPPSTAGPPPLEG 238
                G  GP  + G+   K      G  G S    PP   GPP  +G
Sbjct: 1209 --DAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDG 1253



 Score = 31.2 bits (69), Expect = 0.82
 Identities = 39/154 (25%), Positives = 51/154 (33%), Gaps = 27/154 (17%)

Query: 87   LAGIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPH 146
            L G+   P      G+ G+  P  A    PRG   P G EG  G     G+ GA      
Sbjct: 1149 LQGLPGPPGEKGEVGDVGSMGPHGAP--GPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGE 1206

Query: 147  VSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAH 204
               +  P P    G       +P P         K    E  +  PS   G  G++GP  
Sbjct: 1207 RGDAGDPGPPGAPG-------IPGP---------KGDIGEKGDSGPSGAAGPPGKKGPPG 1250

Query: 205  STGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
              G +       G  G + LP      G P + G
Sbjct: 1251 EDGAK-------GSVGPTGLPGDLGPPGDPGVSG 1277



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 38/145 (26%), Positives = 55/145 (37%), Gaps = 21/145 (14%)

Query: 6   TQTRLAQIPEQARFLM--NLLVTDLNTVV--RQVDHNT---MKLTEQRAYEDDDLHGGGE 58
           T+T    +P     L+  + + T LN  +  R +D ++   +   E +A  +D+      
Sbjct: 291 TETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEEGDDST 350

Query: 59  LAVQLRLAELPERAAVHTRSLGAGRVVRLAGIWRDPAPVMS----HGEAGTPAPRAARLG 114
           +    R AE P R        GAG      G   +PA +       G  G P P+     
Sbjct: 351 MGPDFRAAEYPSRTQFQIFP-GAGE----KGAKGEPAVIEKGQQFEGPPGAPGPQGVV-- 403

Query: 115 APRGASPPPGEEGRAGAWRSPGEAG 139
              G S PPG  G  G    PG AG
Sbjct: 404 ---GPSGPPGPPGFPGDPGPPGPAG 425



 Score = 28.9 bits (63), Expect = 4.1
 Identities = 43/160 (26%), Positives = 60/160 (37%), Gaps = 25/160 (15%)

Query: 90   IWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVST 149
            + +D AP +  GE G P  +    G P G   PPG +G+ G    PG+ G   G    + 
Sbjct: 856  VGQDGAPGIP-GEKGLPGLQGPP-GFP-GPKGPPGHQGKDGRPGHPGQRGEL-GFQGQTG 911

Query: 150  SPTPAPGRRG--GREARLRPM-----------PTPSWIPVSSHKKAARSEPAERRPSLLQ 196
             P PA G  G  G+   + P+           P    +P    ++ A+ E     P    
Sbjct: 912  PPGPA-GVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPL--- 967

Query: 197  GGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPL 236
             G+ GPA   G    K    G G   P  L      P P+
Sbjct: 968  -GKEGPAGLRGFPGPK---GGPGDPGPTGLKGDKGPPGPV 1003



 Score = 28.5 bits (62), Expect = 5.3
 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 13/59 (22%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRG 159
            G+ G P  + ++    +G + PPG+ G  G    PG  G ADG          A GRRG
Sbjct: 1079 GDVGAPGHKGSK--GDKGDAGPPGQPGIRGPAGHPGPPG-ADG----------AQGRRG 1124



 Score = 28.5 bits (62), Expect = 5.3
 Identities = 33/118 (27%), Positives = 38/118 (32%), Gaps = 17/118 (14%)

Query: 118  GASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVS 177
            G   PPGE G  G    PG      G P     P P PG  G         P P  +   
Sbjct: 1409 GLIGPPGEAGEKGDQGLPG----VQGPPGPKGDPGP-PGPIGS-----LGHPGPPGVAGP 1458

Query: 178  SHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRS---PLPLPPSTAG 232
              +K ++  P    P     G  GPA   G         G   R    P+PLP    G
Sbjct: 1459 LGQKGSKGSPGSMGPR----GDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEGG 1512


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 49/164 (29%), Positives = 62/164 (37%), Gaps = 25/164 (15%)

Query: 87  LAGIWRDPAPVMS-----HGEAGTPA-PRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA 140
           L G+  +P P         GE G P  P    L  PRG   PPG  G  GA  SPG  GA
Sbjct: 775 LKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRG---PPGPTGEKGAQGSPGVKGA 831

Query: 141 AD--GSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAE----RRPSL 194
               G P  S S  P    R G++ +     TP         +  + EP E     +  L
Sbjct: 832 TGPVGPPGASVSGPPG---RDGQQGQTGLRGTPG----EKGPRGEKGEPGECSCPSQGDL 884

Query: 195 LQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           +  G  G   + G+        G  G   +P PP   G P L+G
Sbjct: 885 IFSGMPG---APGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQG 925



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 47/157 (29%), Positives = 59/157 (37%), Gaps = 21/157 (13%)

Query: 87   LAGIWRDPAPVMSHGEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAGAADGSP 145
            L GI  +     S GE G P P  +  L  P G + P GE G  G     G+ G   G P
Sbjct: 1100 LPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGF-QGQP 1158

Query: 146  HVSTSPTPA--PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPA 203
                 P P   PG+ G               P     +A +     R PS L G   GP 
Sbjct: 1159 GFPGPPGPPGFPGKVGS--------------PGPPGPQAEKGSEGIRGPSGLPGSP-GPP 1203

Query: 204  HSTGMETQK--EAFDGQGGRSPLPLPPSTAGPPPLEG 238
               G++     +  DG+ G+  L   P  AGPP L G
Sbjct: 1204 GPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMG 1240



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 42/154 (27%), Positives = 54/154 (35%), Gaps = 21/154 (13%)

Query: 82  GRVVRLAGIWRDPAPVMSHGEAGTPAP-RAARLGAPRGASPPPGEEGRAGAWRSPGEAGA 140
           G V  +AG    P P    G  G   P +  + G P G   PPG +G  G    PG  G 
Sbjct: 732 GTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLP-GVQGPPGLKGVQG---EPGPPGR 787

Query: 141 ADGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQR 200
               P         PG +G        +P P   P  + +K A+  P  +       G  
Sbjct: 788 GVQGPQGEPGAPGLPGIQG--------LPGPRGPPGPTGEKGAQGSPGVK-------GAT 832

Query: 201 GPAHSTGMETQ-KEAFDGQGGRSPLPLPPSTAGP 233
           GP    G         DGQ G++ L   P   GP
Sbjct: 833 GPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGP 866



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 39/142 (27%), Positives = 51/142 (35%), Gaps = 29/142 (20%)

Query: 101 GEAGTPAPRAAR----LGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPG 156
           G AG P  +  +       P G+  PPG  G AG   + GE             P PA  
Sbjct: 590 GRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGE----------PCEPCPALS 639

Query: 157 RRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFD 216
                + R+  +P PS           + EP    P     G++G A   G++ QK    
Sbjct: 640 NLQDGDVRVVALPGPS---------GEKGEPGP--PGFGLPGKQGKAGERGLKGQK---- 684

Query: 217 GQGGRSPLPLPPSTAGPPPLEG 238
           G  G    P  P T G P L G
Sbjct: 685 GDAGNPGDPGTPGTTGRPGLSG 706



 Score = 35.8 bits (81), Expect = 0.033
 Identities = 48/172 (27%), Positives = 58/172 (33%), Gaps = 29/172 (16%)

Query: 89   GIWRDPAPVMSHGEAGTPAPRAAR----LGAPRG---ASPPPGEEGRAGAWRSPGEAGAA 141
            G+  DP P    G  G P  +       L  P+G      PPG  GR GA   PG  G  
Sbjct: 1225 GLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQ 1284

Query: 142  D--------GSPHVSTSPTP----APGRRGGREAR-------LRPMPTPSWIPVSSHKKA 182
                     G P     P P    A G +G R A        L   P P   P    +  
Sbjct: 1285 GRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPG 1344

Query: 183  ARSEPAERRPSLLQG--GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAG 232
                  +  P   QG  G  GP    G   QK    G+ GR+ +P  P  +G
Sbjct: 1345 TDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQK-GQAGEKGRAGMPGGPGKSG 1395



 Score = 35.0 bits (79), Expect = 0.057
 Identities = 42/133 (31%), Positives = 53/133 (39%), Gaps = 18/133 (13%)

Query: 115 APRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTP----APGRRG--GREARLRPM 168
           AP G     GE G  G   S GE GA  G+  V  SP      A G +G  G    L   
Sbjct: 331 APSGPKGGKGERGLPGPPGSKGEKGAR-GNDCVRISPDAPLQCAEGPKGEKGESGAL--- 386

Query: 169 PTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMETQK--EAFDGQGGR 221
             PS +P S+ +K  + E  +     + G     G+ G     G + QK    F G  G 
Sbjct: 387 -GPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGL 445

Query: 222 SPLPLPPSTAGPP 234
           +  P PP   GPP
Sbjct: 446 AGEPGPPGLPGPP 458



 Score = 34.3 bits (77), Expect = 0.097
 Identities = 43/165 (26%), Positives = 57/165 (34%), Gaps = 30/165 (18%)

Query: 94   PAPVMSHGEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAG-----AADGSPHV 147
            P  V S G  G    R    L   +G   PPG+ G  GA   PG  G        GS   
Sbjct: 1056 PGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGE 1115

Query: 148  STSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG---------- 197
               P P PG  G        +P P        ++  +    E+     QG          
Sbjct: 1116 KGEPGP-PGSEG--------LPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGP 1166

Query: 198  ----GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                G+ G     G + +K + +G  G S LP  P   GPP ++G
Sbjct: 1167 PGFPGKVGSPGPPGPQAEKGS-EGIRGPSGLPGSPGPPGPPGIQG 1210



 Score = 32.0 bits (71), Expect = 0.48
 Identities = 40/149 (26%), Positives = 54/149 (36%), Gaps = 38/149 (25%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--AADGSPHVSTSPTPAPGRR 158
           GE G P P    L   +G +   G +G+ G   +PG+ G     G P +S      PG +
Sbjct: 656 GEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGE----PGVQ 711

Query: 159 GGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG---------GQRGPAHSTGME 209
           G                  +  K  + +     PS LQG         GQ GP    G E
Sbjct: 712 G-----------------PAGPKGEKGDGCTACPS-LQGTVTDMAGRPGQPGPKGEQGPE 753

Query: 210 TQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                  G+ G+   P  P   GPP L+G
Sbjct: 754 GV-----GRPGKPGQPGLPGVQGPPGLKG 777



 Score = 31.6 bits (70), Expect = 0.63
 Identities = 42/178 (23%), Positives = 61/178 (34%), Gaps = 41/178 (23%)

Query: 101 GEAGTPAPRAARL-GAPRGASPPPGEEGRAGAWRSPGE--AGAADGSPHVS--------- 148
           G  G P P    L G P     PPG +G  G+   PG+   G   G P V          
Sbjct: 450 GPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEV 509

Query: 149 ------------------------TSPTPA---PGRRGGREARLRPMPTPSWIPVSSHKK 181
                                     P PA   PG +G +  +  P  + S +  + H  
Sbjct: 510 CPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLV 569

Query: 182 AARSEPAE-RRPSLLQGGQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           ++     +   P     G  G A   G++ +K  F G+ G +  P PP   GP  ++G
Sbjct: 570 SSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNF-GEAGPAGSPGPPGPVGPAGIKG 626



 Score = 31.6 bits (70), Expect = 0.63
 Identities = 41/129 (31%), Positives = 46/129 (35%), Gaps = 22/129 (17%)

Query: 113  LGAPRGASPPPGEEGRAGAWRSPGEAG--AADGSPHVSTSPTPAPGRRGGRE----ARLR 166
            L  P G     GEEG  G   SPG  G     G P    SP   PG +G R        +
Sbjct: 1022 LPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSP-GLPGLQGERGLTGLTGDK 1080

Query: 167  PMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQKEAFDGQGGRSPL 224
              P P   P           P    P  L G  G+RG   S G    ++   G  G   L
Sbjct: 1081 GEPGPPGQP---------GYPGATGPPGLPGIKGERGYTGSAG----EKGEPGPPGSEGL 1127

Query: 225  PLPPSTAGP 233
            P PP  AGP
Sbjct: 1128 PGPPGPAGP 1136



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 25/77 (32%), Positives = 30/77 (38%), Gaps = 10/77 (12%)

Query: 96   PVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAP 155
            P    G  G P P+     A  G     GE+GRAG    PG++G        S  P   P
Sbjct: 1354 PPGKQGFYGPPGPKGDPGAA--GQKGQAGEKGRAGMPGGPGKSG--------SMGPVGPP 1403

Query: 156  GRRGGREARLRPMPTPS 172
            G  G R     P P+ S
Sbjct: 1404 GPAGERGHPGAPGPSGS 1420


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 49/184 (26%), Positives = 58/184 (31%), Gaps = 47/184 (25%)

Query: 94  PAPVMSHGEAGTPAPRAAR----------LGAPRGASPPPGEEGRAGAWRSPGEAGAADG 143
           P P  S GE+G P P                 P+G    PG+ G  G    PG  G    
Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610

Query: 144 SPHVSTSPTPAPGRRGGREARLRPMPTPSWI---------------------------PV 176
           +        P P   GG +    P P P  +                           P 
Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGP-PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPG 669

Query: 177 SSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPP 234
           +   K     P ER P  L G  G RG A   G E       G+G   P P PP  AG P
Sbjct: 670 APGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPE------GGKGAAGP-PGPPGAAGTP 722

Query: 235 PLEG 238
            L+G
Sbjct: 723 GLQG 726



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 49/168 (29%), Positives = 61/168 (36%), Gaps = 35/168 (20%)

Query: 94   PAPVMSHGEAGTP-------APRAARLGAPRGASPPPGEEGRAGAWRSPGEAG----AAD 142
            P P  S G+ G P       AP +  +  P+G +  PGE+G  GA   PG  G    A  
Sbjct: 893  PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGI 952

Query: 143  GSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG----- 197
                    P   PG RG         P P  +   S K  A     ER P   QG     
Sbjct: 953  TGARGLAGPPGMPGPRGS--------PGPQGVKGESGKPGANGLSGERGPPGPQGLPGLA 1004

Query: 198  ------GQRGPAHSTGMETQKEAFDGQGGR----SP-LPLPPSTAGPP 234
                  G+ G   S G+  +  +  G+G R    SP  P  P   GPP
Sbjct: 1005 GTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPP 1052



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 48/144 (33%), Positives = 56/144 (38%), Gaps = 23/144 (15%)

Query: 101 GEAGTPAPRA--ARLGAP--RGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPG 156
           G+AG P  R      GAP  RG + PPG EG  GA   PG  GAA G+P +       PG
Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAA-GTPGLQ----GMPG 729

Query: 157 RRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQKEA 214
            RGG  +     P P           A   P +  P    G  G  GPA   G +     
Sbjct: 730 ERGGLGS-----PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDK----- 779

Query: 215 FDGQGGRSPLPLPPSTAGPPPLEG 238
             G+GG   LP      G P   G
Sbjct: 780 --GEGGAPGLPGIAGPRGSPGERG 801



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 45/140 (32%), Positives = 51/140 (36%), Gaps = 24/140 (17%)

Query: 101 GEAGTPAPRAARLGAPRGASP--PPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRR 158
           GE G P       G P G+ P  PPG +G  G   SPG  GAA G P     P P PG  
Sbjct: 834 GEGGPPGVA----GPPGGSGPAGPPGPQGVKGERGSPGGPGAA-GFPGARGLPGP-PGSN 887

Query: 159 GGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEAFDGQ 218
           G         P P   P  S  K     PA    +    G  GP    G   +K +   Q
Sbjct: 888 GN--------PGPPG-PSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQ 938

Query: 219 GGRSPLPLPPSTAGPPPLEG 238
           G       PP   GP  + G
Sbjct: 939 G-------PPGAPGPLGIAG 951



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 48/161 (29%), Positives = 61/161 (37%), Gaps = 27/161 (16%)

Query: 94  PAPVMSHGEAGTP-APRAARLGAPRGASPP---------PGEEGRAGAWRSPGEAGAADG 143
           P P    GE G P A        PRG + P         PG++G  GA   PG AG   G
Sbjct: 737 PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPR-G 795

Query: 144 SPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----G 198
           SP      T  PG  G   A     P  +  P    ++ A  E  E  P  + G     G
Sbjct: 796 SPG-ERGETGPPGPAGFPGA-----PGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSG 849

Query: 199 QRGPAHSTGMETQKEAFDGQG-----GRSPLPLPPSTAGPP 234
             GP    G++ ++ +  G G     G   LP PP + G P
Sbjct: 850 PAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNP 890



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 45/142 (31%), Positives = 53/142 (37%), Gaps = 16/142 (11%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--AADGSPHVSTSPTPAPGRR 158
           GE G P  R      P G +  PGE+G AG   +PG AG   A G P     P   PG R
Sbjct: 483 GERGAPGFRG-----PAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP-GGPGMR 536

Query: 159 GGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQK--EAFD 216
           G   +   P       P  S  ++ R  P    PS    G RG     G    K  +   
Sbjct: 537 GMPGSPGGPGSDGKPGPPGSQGESGR--PGPPGPS----GPRGQPGVMGFPGPKGNDGAP 590

Query: 217 GQGGRSPLPLPPSTAGPPPLEG 238
           G+ G    P  P   GPP   G
Sbjct: 591 GKNGERGGPGGPGPQGPPGKNG 612



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 46/163 (28%), Positives = 58/163 (35%), Gaps = 24/163 (14%)

Query: 87   LAGIWRDPAPVMSHGEAGTPAPRAARLG-APRGASPPPGEEGRAGAWRSPGEAGAA---- 141
            LAG   +P    + G  G P    +  G   RG +  PG  G  G    PG  G A    
Sbjct: 1003 LAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSG 1062

Query: 142  DGSPHVSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG---- 197
            D        P  APG  G R A           P     +  + E  ER  + ++G    
Sbjct: 1063 DRGESGPAGPAGAPGPAGSRGA-----------PGPQGPRGDKGETGERGAAGIKGHRGF 1111

Query: 198  -GQRGPAHSTGMETQKEAFDGQGGRSPL-PLPPSTAGPPPLEG 238
             G  G   S G   Q+ A    G   P  P+ PS  GPP  +G
Sbjct: 1112 PGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPS--GPPGKDG 1152



 Score = 36.2 bits (82), Expect = 0.026
 Identities = 45/167 (26%), Positives = 57/167 (34%), Gaps = 29/167 (17%)

Query: 99  SHGEAGTPAP--RAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPG 156
           S G+ G P P   A   G+P GA    G  G  G+  +PG+ G      H      P P 
Sbjct: 328 SDGQPGPPGPPGTAGFPGSP-GAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPP 386

Query: 157 RRGGREARLRPMPTPSWIPVSSHKKAARSEP----AERRPSLLQG--------------- 197
              G       M  P+ IP +     AR  P    A   P L  G               
Sbjct: 387 GINGSPGGKGEM-GPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGP 445

Query: 198 -GQRGPAHSTGM-----ETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            G+RG A   G+     E  K+   G+ G + LP      G P   G
Sbjct: 446 RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRG 492



 Score = 35.0 bits (79), Expect = 0.057
 Identities = 41/142 (28%), Positives = 45/142 (31%), Gaps = 22/142 (15%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRGG 160
           G AG P P       P G   PPG  G  G+  SPG  G          S  P P    G
Sbjct: 168 GLAGYPGP-----AGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG 222

Query: 161 REARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQK--EAFD 216
                     PS       +      P ER    L G  G +GPA   G    K    FD
Sbjct: 223 ----------PSGPAGKDGESGRPGRPGERG---LPGPPGIKGPAGIPGFPGMKGHRGFD 269

Query: 217 GQGGRSPLPLPPSTAGPPPLEG 238
           G+ G       P   G   L G
Sbjct: 270 GRNGEKGETGAPGLKGENGLPG 291



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 44/166 (26%), Positives = 58/166 (34%), Gaps = 31/166 (18%)

Query: 103 AGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGA--ADGSPHVSTSPTPAPG---- 156
           A T  P       P+G   PPG  GR G    PG+ G+  + G P +  S    P     
Sbjct: 94  APTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSP 153

Query: 157 -------RRGGREARLRPMPTPSWIP-------VSSHKKAARS--------EPAERRPSL 194
                  + G     L   P P+  P        S H  +  S        EP +  PS 
Sbjct: 154 QYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSG 213

Query: 195 LQG--GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
             G  G  GP+   G + +     G+ G   LP PP   GP  + G
Sbjct: 214 PPGPPGAIGPSGPAGKDGE-SGRPGRPGERGLPGPPGIKGPAGIPG 258



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 50/172 (29%), Positives = 59/172 (34%), Gaps = 52/172 (30%)

Query: 101 GEAGTPAPRAAR-LGAPRGASPP------PGEEGRAGAWRSPGEAGA--------ADGSP 145
           GE G P  +    L    GA  P      PGE GR G    PG AGA        +DG P
Sbjct: 276 GETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGL---PGAAGARGNDGARGSDGQP 332

Query: 146 HVSTSPTPAPGRRG-----GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--- 197
                P   PG  G     G +  + P  +P     S+     R EP  +  +  QG   
Sbjct: 333 ----GPPGPPGTAGFPGSPGAKGEVGPAGSPG----SNGAPGQRGEPGPQGHAGAQGPPG 384

Query: 198 -----------GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                      G+ GPA   G      A    G R P P P    G P L G
Sbjct: 385 PPGINGSPGGKGEMGPAGIPG------APGLMGARGP-PGPAGANGAPGLRG 429



 Score = 32.0 bits (71), Expect = 0.48
 Identities = 24/77 (31%), Positives = 28/77 (36%), Gaps = 17/77 (22%)

Query: 94   PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG-----------AAD 142
            P P    G  G+P P       PRG   P G  G+ G    PG  G            ++
Sbjct: 1121 PGPAGQQGAIGSPGP-----AGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSE 1175

Query: 143  GSPHVSTSPTPAPGRRG 159
            GSP     P P PG  G
Sbjct: 1176 GSPGHPGQPGP-PGPPG 1191



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 16/43 (37%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 101  GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADG 143
            G  G P PR  R    RG+   PG  G+ G    PG  G   G
Sbjct: 1158 GPIGPPGPRGNR--GERGSEGSPGHPGQPGPPGPPGAPGPCCG 1198


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 41/140 (29%), Positives = 50/140 (35%), Gaps = 28/140 (20%)

Query: 96  PVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGA-WRSPGEAGAADGSPHVSTSPTPA 154
           P       G PA  AA    P  A PPP     A A  R+P  A AA  +P     P+P 
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP-----PSPG 163

Query: 155 PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQKEA 214
           P + G R  R  P+  P   P         + PA   P+   G +R P  +         
Sbjct: 164 PAQPGPRAQRAAPLAAPPPAPA--------APPAVAPPA---GPRRAPPPAVAAR----- 207

Query: 215 FDGQGGRSPLPLPPSTAGPP 234
                   PLP PP    PP
Sbjct: 208 ------EPPLPPPPQPPAPP 221



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 39/133 (29%), Positives = 48/133 (36%), Gaps = 7/133 (5%)

Query: 94  PAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEG----RAGAWRSPGEAGAADGSPHVST 149
           PAPV +   A   APRAA   A    SP P + G    RA    +P  A AA  +     
Sbjct: 137 PAPVAAAAPAR--APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPA 194

Query: 150 SPTPAPGRR-GGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGM 208
            P  AP      RE  L P P P   P        + +P     ++  GG   P     +
Sbjct: 195 GPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREV 254

Query: 209 ETQKEAFDGQGGR 221
                   G GGR
Sbjct: 255 VRYLGGSGGAGGR 267



 Score = 28.9 bits (63), Expect = 4.1
 Identities = 44/164 (26%), Positives = 54/164 (32%), Gaps = 51/164 (31%)

Query: 108 PRAARLG-APRGASPPPGEEGRAGAWR-------------SPGEAGAADGSPHVSTSPTP 153
           PR  R G AP  AS  P    R G  R                E   ++GS  V  S  P
Sbjct: 298 PRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGS-EVPESDRP 356

Query: 154 AP-------GRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHST 206
           A        G RG + A+ R      W P   H+               Q   RGPA  +
Sbjct: 357 AGAQHHQLNGERGPQSAKER---VKEWTPCGPHQG--------------QDEGRGPAPGS 399

Query: 207 GMET--QKEAFDGQGGR----------SPLPLPPSTAGPPPLEG 238
           G        A + +GG           SP+PLPP     P  +G
Sbjct: 400 GTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPALPGADG 443


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 46/152 (30%), Positives = 56/152 (36%), Gaps = 31/152 (20%)

Query: 96   PVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPA- 154
            P    G  G+P P    +G P G   PPGE G AG    PG+ G  DG P  + SP P  
Sbjct: 1328 PPGDDGPKGSPGP----VGFP-GDPGPPGEPGPAGQDGPPGDKG-DDGEPGQTGSPGPTG 1381

Query: 155  -------PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTG 207
                   PG+RG         P P+       +K A+ E     P     G+ GP    G
Sbjct: 1382 EPGPSGPPGKRG--------PPGPAGPEGRQGEKGAKGEAGLEGPP----GKTGPIGPQG 1429

Query: 208  METQK-----EAFDGQGGRSPLPLPPSTAGPP 234
               +          G  G   LP  P   GPP
Sbjct: 1430 APGKPGPDGLRGIPGPVGEQGLPGSPGPDGPP 1461



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 43/158 (27%), Positives = 55/158 (34%), Gaps = 33/158 (20%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPA-PGRRG 159
           GE G P PR        G   P G +GR G    PG  G       +     P  PGR+G
Sbjct: 829 GEIGPPGPR--------GEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQG 880

Query: 160 GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMETQKEA 214
            + +   P       P ++ +K  R  P +  P   +G     G+RGP   TG    K  
Sbjct: 881 PKGSIGFP-----GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGN 935

Query: 215 FDGQGGRSP--------------LPLPPSTAGPPPLEG 238
             G G   P               P P    GPP  +G
Sbjct: 936 SGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDG 973



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 45/152 (29%), Positives = 54/152 (35%), Gaps = 16/152 (10%)

Query: 94   PAPVMSHGEAGTPAPRAARLG-----APRGASPPPGEEGRAGAWRSPGEAGAADGSPHVS 148
            P P  + GE G P  +    G      PRG   PPG  G  G    PGE G       + 
Sbjct: 1191 PGPSGADGEPG-PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMG 1249

Query: 149  TSPTPAPGRRGGREARLRPMPTPSWI--PVSSHKKAARSEPAERRPSLLQGGQRGPAHST 206
                P P    G      P   P  I  P +  +K    E  E  P L   G+ GP    
Sbjct: 1250 PPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGE--PGL--PGEGGPPGPK 1305

Query: 207  GMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            G   +K    G+ G S    PP   GPP  +G
Sbjct: 1306 GERGEK----GESGPSGAAGPPGPKGPPGDDG 1333



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 32/82 (39%), Positives = 38/82 (46%), Gaps = 9/82 (10%)

Query: 87  LAGIWRDPAP---VMSHGEAGTPA----PRAARLGAPRGASPPPGEEGRAGAWRSPGEAG 139
           + G+   P P   V   GE G P     P A  L  P+GA  PPGE+G  G    PG  G
Sbjct: 698 VTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPG 757

Query: 140 AADGSPHVSTSPTPAPGRRGGR 161
            ADG P       P PG +GG+
Sbjct: 758 -ADGPPGHPGKEGP-PGEKGGQ 777



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 47/157 (29%), Positives = 57/157 (36%), Gaps = 18/157 (11%)

Query: 93   DPAPVMSHGEAGTPAPRAARLGAP--RGASPPPGEEGRAGAWRSPGEAGAADGSPHVS-- 148
            +P    S G  G P P     G P  RG   P G EGR G   + GEAG  +G P  +  
Sbjct: 1370 EPGQTGSPGPTGEPGPS----GPPGKRGPPGPAGPEGRQGEKGAKGEAG-LEGPPGKTGP 1424

Query: 149  TSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHST 206
              P  APG+ G     LR +P P               P    P  L G  G  GP    
Sbjct: 1425 IGPQGAPGKPG--PDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEK 1482

Query: 207  GME-----TQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            G              G+ G   LP P  ++GP   +G
Sbjct: 1483 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQG 1519



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 50/174 (28%), Positives = 56/174 (32%), Gaps = 32/174 (18%)

Query: 89  GIWRDPAPVMSHGEAGTPA-PRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHV 147
           G+   P PV   G  G    P       PRG   PPG  G+ G     G  GA  G P  
Sbjct: 565 GLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR-GMPG- 622

Query: 148 STSP---------TPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG- 197
            T P            PG +G R       P PS  P        R +  E  P  L G 
Sbjct: 623 QTGPKGDRGFDGLAGLPGEKGHRGD-----PGPSGPPGPPGDDGERGDDGEVGPRGLPGE 677

Query: 198 -------------GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
                        G  GP   TGM+ Q     G  G    P PP   G P  +G
Sbjct: 678 PGPRGLLGPKGPPGPPGPPGVTGMDGQPGP-KGNVGPQGEPGPPGQQGNPGAQG 730



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 45/170 (26%), Positives = 56/170 (32%), Gaps = 33/170 (19%)

Query: 101  GEAGTPAPRAARLG--APRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRR 158
            G+ G P P    +G   P G + P GE G  G    PGE G    +    T   P P   
Sbjct: 988  GKTGPPGPPGV-VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGL 1046

Query: 159  GGREA--RLRPMPTPSWIPVSSHKKAAR------------SEPAERRPSLLQG------- 197
             G++    LR  P    +P        +              P ER P+   G       
Sbjct: 1047 PGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGR 1106

Query: 198  ----GQRGPAHSTGMETQK-----EAFDGQGGRSPLPLPPSTAGPPPLEG 238
                G  GPA   G   +K        DG  G   LP P    GPP  +G
Sbjct: 1107 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDG 1156



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 44/158 (27%), Positives = 56/158 (35%), Gaps = 20/158 (12%)

Query: 96   PVMSHGEAGTPAPRAAR-LGAPRGASPPPGEEGRAGAWRSPGEAG-----AADGSPHVST 149
            P    GE G   P+       P+G   PPG++G  G     GE G        G P V  
Sbjct: 941  PAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV-V 999

Query: 150  SPTPAPGRRGGREARLRP----MPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQR 200
             P    G  G    R  P     P    +P  + K+  + +P    P+ L G     G R
Sbjct: 1000 GPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPG---PAGLPGKDGPPGLR 1056

Query: 201  GPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
            G     G+     A   +G   P P PP  AG P   G
Sbjct: 1057 GFPGDRGLPGPVGALGLKGNEGP-PGPPGPAGSPGERG 1093



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 42/148 (28%), Positives = 51/148 (34%), Gaps = 19/148 (12%)

Query: 104 GTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAG--------AADGSPHVSTSPTPAP 155
           G P P       P G   PPG  G  G    PGE G         ADG P    +    P
Sbjct: 469 GPPGPEG-----PAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLP 523

Query: 156 GRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG-----GQRGPAHSTGMET 210
            R GG        P  S     +     ++  A R P+   G     G  GP  S G++ 
Sbjct: 524 FRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKG 583

Query: 211 QKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           +      QG R  +  PP  AG P   G
Sbjct: 584 EPGDVGPQGPRG-VQGPPGPAGKPGRRG 610



 Score = 34.7 bits (78), Expect = 0.075
 Identities = 44/160 (27%), Positives = 53/160 (33%), Gaps = 23/160 (14%)

Query: 94   PAPVMSHGEAGTPAPRAAR----------LGAPRGASPPPGEEGRAGAWRSPGEAGA--- 140
            P P    G  G   P+             L  P G   PPGE+G  G    PG+ G+   
Sbjct: 1113 PGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGD 1172

Query: 141  -ADGSPHVSTSPTPAPGRRGGREARLRPMPT-PSWIPVSSHKKAARSEPAERRPSLLQGG 198
              +  P   T P    G+ G   A   P P     +      +  R  P    P  LQ G
Sbjct: 1173 KGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQ-G 1231

Query: 199  QRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
              GP    G ET      G  G+   P PP   GP    G
Sbjct: 1232 LPGPPGEKG-ET------GDVGQMGPPGPPGPRGPSGAPG 1264



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 45/161 (27%), Positives = 53/161 (32%), Gaps = 52/161 (32%)

Query: 101 GEAGTPAP-------------RAARLGAPRGASPPPGEEGRAGAWRSPGEAG-------- 139
           G+AG+  P             + ARL A RG + P G  GR G    PG  G        
Sbjct: 530 GDAGSKGPMVSAQESQAQAILQQARL-ALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDV 588

Query: 140 AADGSPHVSTSPTPA--PGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG 197
              G   V   P PA  PGRRG                       A S+ A   P     
Sbjct: 589 GPQGPRGVQGPPGPAGKPGRRG----------------------RAGSDGARGMP----- 621

Query: 198 GQRGPAHSTGMETQKEAFDGQGGRSPLPLPPSTAGPPPLEG 238
           GQ GP    G +       G+ G    P P    GPP  +G
Sbjct: 622 GQTGPKGDRGFD-GLAGLPGEKGHRGDPGPSGPPGPPGDDG 661



 Score = 29.3 bits (64), Expect = 3.1
 Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 6/73 (8%)

Query: 89   GIWRDPAPVMSHGEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVS 148
            GI     P+   G  G P P   +    +G+S P G +G AG    PG  G   G P   
Sbjct: 1519 GITGPSGPIGPPGPPGLPGPPGPK--GAKGSSGPTGPKGEAG---HPGPPG-PPGPPGEV 1572

Query: 149  TSPTPAPGRRGGR 161
              P P    R  R
Sbjct: 1573 IQPLPIQASRTRR 1585


>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
          Length = 957

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 39/131 (29%), Positives = 58/131 (44%), Gaps = 13/131 (9%)

Query: 99  SHGEAGTPA-PRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGR 157
           + GE G P  P    L   +G   PPG++G+ GA   PG  G ++GSP         PG 
Sbjct: 600 TRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMG-SNGSP----GQPGTPGS 654

Query: 158 RGGR-EARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQG--GQRGPAHSTGMETQKEA 214
           +G + E  ++ MP  S +        +  EP       +QG  G +G     G++ QK  
Sbjct: 655 KGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQK-- 712

Query: 215 FDGQGGRSPLP 225
             G+ GR  +P
Sbjct: 713 --GENGRQGIP 721



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 14/146 (9%)

Query: 99  SHGEAGTPAPRAARLGAP--RGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPA-- 154
           S G+ GTP  + ++ G P  +G     G +G  GA  SPGE G   G P +         
Sbjct: 645 SPGQPGTPGSKGSK-GEPGIQGMPGASGLKGEPGATGSPGEPGYM-GLPGIQGKKGDKGN 702

Query: 155 PGRRG--GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQK 212
            G +G  G++        P    +  H   A+ E  E+     + G RG   S G E+  
Sbjct: 703 QGEKGIQGQKGENGRQGIPGQQGIQGHH-GAKGERGEKG----EPGVRGAIGSKG-ESGV 756

Query: 213 EAFDGQGGRSPLPLPPSTAGPPPLEG 238
           +   G  G    P  P   GPP L+G
Sbjct: 757 DGLMGPAGPKGQPGDPGPQGPPGLDG 782



 Score = 32.0 bits (71), Expect = 0.48
 Identities = 43/143 (30%), Positives = 51/143 (35%), Gaps = 26/143 (18%)

Query: 101 GEAGTPAPRAARLGAPRGASPPPGEEGRAGAWRSP---GEAGAADGSPHVSTSPTPA--- 154
           G AG P       G P G +  PG  G+ G   SP   GEAG+        T   P    
Sbjct: 557 GNAGFP-------GLP-GPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPG 608

Query: 155 -PGRRG--GREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHSTGMETQ 211
            PG RG  G++  + P       P    KK A   P     S    GQ G   S G + +
Sbjct: 609 FPGNRGLMGQKGEIGP-------PGQQGKKGAPGMPG-LMGSNGSPGQPGTPGSKGSKGE 660

Query: 212 KEAFDGQGGRSPLPLPPSTAGPP 234
                G  G S L   P   G P
Sbjct: 661 -PGIQGMPGASGLKGEPGATGSP 682


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 38/140 (27%), Positives = 52/140 (37%), Gaps = 11/140 (7%)

Query: 92   RDPAPVMSHG----EAGTPAPRAARLG-APRGASPPPGEEGRAGAWRSPGEAGAADGSPH 146
            +DP P  S        G P P    L   P  ++ P G +      R P  AG +  SPH
Sbjct: 1024 QDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPH 1083

Query: 147  VSTSPTPAPGRRGGREARLRPMPTPSWIPVSSHKKAARSEPAERRPSLLQGGQRGPAHST 206
            +  SP P+PG        + P P  +  P    + AA ++     P    GG + P    
Sbjct: 1084 LVPSPAPSPG-----PGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQ 1138

Query: 207  GMETQKEAFDGQGGRSPLPL 226
             +  Q    D   GR P  L
Sbjct: 1139 PL-LQPTKVDAAEGRRPQAL 1157


>gi|6754638 microtubule-associated protein tau isoform 2 [Homo
           sapiens]
          Length = 441

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 40/156 (25%), Positives = 59/156 (37%), Gaps = 23/156 (14%)

Query: 57  GELAVQLRLAELPERAAVHTRSLG---------AGRVVRLAGIWRDPAPVMSHGEAGTPA 107
           G+ A      E+PE        +G         AG V +   + +      S  +    A
Sbjct: 86  GKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGA 145

Query: 108 PRAARLGAPRGASPPPGEEGRAGAWRSPGEAGAADGSPHVSTSPTPAPGRRG-------- 159
               ++  PRGA+PP G++G+A A R P +   A  +P  S  P  +  R G        
Sbjct: 146 DGKTKIATPRGAAPP-GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPG 204

Query: 160 --GREARLRPMPTPSWIPVSSHKKAARSEPAERRPS 193
             G  +R   +PTP   P    KK A      + PS
Sbjct: 205 TPGSRSRTPSLPTP---PTREPKKVAVVRTPPKSPS 237


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,584,617
Number of Sequences: 37866
Number of extensions: 848645
Number of successful extensions: 9524
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 207
Number of HSP's successfully gapped in prelim test: 952
Number of HSP's that attempted gapping in prelim test: 5101
Number of HSP's gapped (non-prelim): 3251
length of query: 238
length of database: 18,247,518
effective HSP length: 99
effective length of query: 139
effective length of database: 14,498,784
effective search space: 2015330976
effective search space used: 2015330976
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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