Guide to the Human Genome
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Search of human proteins with 239754651

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239754651 PREDICTED: hypothetical protein XP_002346061 [Homo
sapiens]
         (368 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754651 PREDICTED: hypothetical protein XP_002346061 [Homo ...   752   0.0  
gi|239749205 PREDICTED: hypothetical protein XP_002346953 [Homo ...   502   e-142
gi|239743285 PREDICTED: hypothetical protein XP_002342817 [Homo ...   502   e-142
gi|239508969 PREDICTED: hypothetical protein [Homo sapiens]           502   e-142
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    55   1e-07
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    51   1e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    51   1e-06
gi|117938759 GNAS complex locus XLas [Homo sapiens]                    51   2e-06
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 50   3e-06
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       49   9e-06
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      48   2e-05
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                48   2e-05
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  47   2e-05
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      47   3e-05
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     47   3e-05
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap...    47   4e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    46   6e-05
gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]           45   8e-05
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        45   8e-05
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          45   1e-04
gi|12707580 paired-like homeobox 2b [Homo sapiens]                     45   1e-04
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]               45   1e-04
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    45   1e-04
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    45   1e-04
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    45   1e-04
gi|38150007 small nuclear ribonucleoprotein polypeptide B/B' iso...    45   1e-04
gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isof...    45   1e-04
gi|22027609 alpha 1 type XIII collagen isoform 19 [Homo sapiens]       45   1e-04
gi|22027601 alpha 1 type XIII collagen isoform 15 [Homo sapiens]       45   1e-04
gi|91208420 bassoon protein [Homo sapiens]                             44   2e-04

>gi|239754651 PREDICTED: hypothetical protein XP_002346061 [Homo
           sapiens]
          Length = 368

 Score =  752 bits (1942), Expect = 0.0
 Identities = 368/368 (100%), Positives = 368/368 (100%)

Query: 1   MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR 60
           MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR
Sbjct: 1   MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR 60

Query: 61  APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120
           APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP
Sbjct: 61  APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120

Query: 121 DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV 180
           DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV
Sbjct: 121 DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV 180

Query: 181 GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP 240
           GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP
Sbjct: 181 GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP 240

Query: 241 SPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKAR 300
           SPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKAR
Sbjct: 241 SPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKAR 300

Query: 301 GSRSRRRYLWRWDSAAGVAGGARAALSSSAAEAAAAAAAAAAARMDFLSGPSPAASAASP 360
           GSRSRRRYLWRWDSAAGVAGGARAALSSSAAEAAAAAAAAAAARMDFLSGPSPAASAASP
Sbjct: 301 GSRSRRRYLWRWDSAAGVAGGARAALSSSAAEAAAAAAAAAAARMDFLSGPSPAASAASP 360

Query: 361 ERRDPARQ 368
           ERRDPARQ
Sbjct: 361 ERRDPARQ 368


>gi|239749205 PREDICTED: hypothetical protein XP_002346953 [Homo
           sapiens]
          Length = 261

 Score =  502 bits (1292), Expect = e-142
 Identities = 243/246 (98%), Positives = 244/246 (99%)

Query: 1   MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR 60
           MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR
Sbjct: 1   MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR 60

Query: 61  APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120
           APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP
Sbjct: 61  APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120

Query: 121 DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV 180
           DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV
Sbjct: 121 DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV 180

Query: 181 GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP 240
           GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP
Sbjct: 181 GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP 240

Query: 241 SPLRSG 246
           SP+  G
Sbjct: 241 SPVWPG 246


>gi|239743285 PREDICTED: hypothetical protein XP_002342817 [Homo
           sapiens]
          Length = 261

 Score =  502 bits (1292), Expect = e-142
 Identities = 243/246 (98%), Positives = 244/246 (99%)

Query: 1   MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR 60
           MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR
Sbjct: 1   MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR 60

Query: 61  APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120
           APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP
Sbjct: 61  APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120

Query: 121 DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV 180
           DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV
Sbjct: 121 DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV 180

Query: 181 GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP 240
           GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP
Sbjct: 181 GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP 240

Query: 241 SPLRSG 246
           SP+  G
Sbjct: 241 SPVWPG 246


>gi|239508969 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 261

 Score =  502 bits (1292), Expect = e-142
 Identities = 243/246 (98%), Positives = 244/246 (99%)

Query: 1   MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR 60
           MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR
Sbjct: 1   MRASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGR 60

Query: 61  APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120
           APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP
Sbjct: 61  APPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120

Query: 121 DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV 180
           DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV
Sbjct: 121 DVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAV 180

Query: 181 GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP 240
           GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP
Sbjct: 181 GEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP 240

Query: 241 SPLRSG 246
           SP+  G
Sbjct: 241 SPVWPG 246


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 78/304 (25%), Positives = 104/304 (34%), Gaps = 43/304 (14%)

Query: 66  GPVGVGPLVPDLEEGVPGAR------GHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGI 119
           G  G GP  P   EG PGA       G +    G P+                     G 
Sbjct: 69  GAAGAGPAAP--AEGAPGAAPEPPPAGRARPGGGGPQRP-------------------GP 107

Query: 120 PDVAVEVVVASEQQPSAA-REGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGV 178
           P     +V A    P+A  R    G A     +     +  GP  E A  G  +  G   
Sbjct: 108 PSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGP--EPAPAGPAKPAGPAA 165

Query: 179 AVGEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGP 238
                    GP  G G G   G+  G G       + L    +   + H   P  +    
Sbjct: 166 LAARAGPGPGPGPGPGPGPGPGKPAGPG-----AAQTLNGSAALLNSHHAAAPAVSLVNN 220

Query: 239 GPSPLRSGHQVPSPGSVLS--PHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRP 296
           GP+ L    +  +PG+V+   P +    PP+ A         +P P  P A  PP PP P
Sbjct: 221 GPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPA---APAPAAPAAAPPPPPPAP 277

Query: 297 QKARGSRSRRRYLWRWDSAAGVAGGARAALSSSAAEAAAAAAAAAAARMDFLSGPSPAAS 356
             A  +R          +A  V   A AA +  +A AA A A AA         P P A+
Sbjct: 278 --ATLARPPGHPAGPPTAAPAVPPPA-AAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA 334

Query: 357 AASP 360
           AA+P
Sbjct: 335 AAAP 338



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 60/229 (26%), Positives = 76/229 (33%), Gaps = 35/229 (15%)

Query: 171 VRAGGEGVAVGEELQDTGPRWGEGEGEEQGRE--PGSGNTTGTLGKELVSQVSTRRAVHP 228
           VRA   G A+G  +    P    G G     E  PG+       G+        +R   P
Sbjct: 50  VRAAAAG-ALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRP-GP 107

Query: 229 PTPKRARTGPGPSPLRSGHQVPSPGSVLS-------------PHMLFGHPPSAAGGGDSG 275
           P+P+R     GP+P  +  + P  GS  S             P      P   AG     
Sbjct: 108 PSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALA 167

Query: 276 GEGSPEPLLPPAQGP-PAPPRP------QKARGSRSRRRYLWRWDSAAGVAGGARAALSS 328
               P P   P  GP P P +P      Q   GS +          A  +     AAL  
Sbjct: 168 ARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLP 227

Query: 329 SAAEAA-----------AAAAAAAAARMDFLSGPSPAASAASPERRDPA 366
               AA            AAA  A A     + P+PAA AA+P    PA
Sbjct: 228 LPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPA 276


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 85/311 (27%), Positives = 102/311 (32%), Gaps = 52/311 (16%)

Query: 19  SGGPGRNQTWVGGQGPKAP--WPGEGGWDCASPAALACSVGMGRAPPGLGPVG-VGPLVP 75
           SG PG N    G  GP  P   PGE G     PA  A + G    P   GP G VGP   
Sbjct: 311 SGSPGEN----GSPGPMGPRGLPGERGR--TGPAGAAGARGNDGQPGPAGPPGPVGPAGG 364

Query: 76  DLEEGVPGARGHSHAI-VGDPEAAHAVVVASEDSSVTCTVALHGIPDV-AVEVVVASEQQ 133
               G PGA+G +       PE A                   G P    +     S   
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 424

Query: 134 PSAARE----GNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGP 189
           P  A      G RG        G      +GP+ +    G+    GE    GE     GP
Sbjct: 425 PGIAGAPGFPGPRGPPGPQGATGP-----LGPKGQTGEPGIAGFKGEQGPKGEP-GPAGP 478

Query: 190 RWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRA---RTGPGPSPLRSG 246
           +   G   E+G+    G   G               + PP  + A   R  PG   L   
Sbjct: 479 QGAPGPAGEEGKRGARGEPGGV------------GPIGPPGERGAPGNRGFPGQDGLAGP 526

Query: 247 HQVPS---PGSVLSPHMLFGHP--------PSAAG----GGDSGGEGSPEPLLPPAQ-GP 290
              P    P  +  P    G P        P A G     GD+G +G   P   P + G 
Sbjct: 527 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 586

Query: 291 PAPPRPQKARG 301
           P PP PQ ARG
Sbjct: 587 PGPPGPQGARG 597



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 72/275 (26%), Positives = 89/275 (32%), Gaps = 52/275 (18%)

Query: 60   RAPPG-LGPVGV-GPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALH 117
            R PPG +GP G+ GP      EG PGA G        P           D   T  V   
Sbjct: 1016 RGPPGPVGPPGLTGPAGEPGREGSPGADG--------PPGRDGAAGVKGDRGETGAVGAP 1067

Query: 118  GIPDVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEG 177
            G P        A        ++G+RG+A     MG        P     ARG+     +G
Sbjct: 1068 GAPGPPGSPGPAGP----TGKQGDRGEAGAQGPMG--------PSGPAGARGI-----QG 1110

Query: 178  VAVGEELQDTGPRWGEGEGEEQGREPGSGNT--TGTLGKELVSQVSTRRAVHPPTPKRAR 235
                      GPR  +GE  E G     G+   TG  G       S  +    P      
Sbjct: 1111 --------PQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP 1162

Query: 236  TGP----GPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPP 291
             GP    GPS     + +P P     P    G    A   G+ G  G P        GPP
Sbjct: 1163 RGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP--------GPP 1214

Query: 292  APPRPQKA---RGSRSRRRYLWRWDSAAGVAGGAR 323
             P     A    G R +     ++  A   AGG R
Sbjct: 1215 GPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLR 1249



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 79/313 (25%), Positives = 103/313 (32%), Gaps = 67/313 (21%)

Query: 20  GGPGRNQTWVGGQGPKAPWPGEGG--WDCASPAALACSVGMGRAPPGLGPVGVGPLVPDL 77
           G PG +  + G  GP  P PGEGG   D   P       G   AP  +GP G        
Sbjct: 657 GAPGPSG-FQGLPGPPGP-PGEGGKPGDQGVP-------GEAGAPGLVGPRG-------- 699

Query: 78  EEGVPGARGHSHA--------IVGDP--EAAHAVVVASEDSSVTCTVALHGIPDVAVEVV 127
           E G PG RG   A        + G P  +        +          L G+P       
Sbjct: 700 ERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG------ 753

Query: 128 VASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVR---------AGGEGV 178
               ++ +A   G +GD  D     V E+   G   ++  RG+           A GE  
Sbjct: 754 ----ERGAAGIAGPKGDRGD-----VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG 804

Query: 179 AVGEE--LQDTGPRWGEGEGEEQGRE--------PGSGNTTGTLGKELVSQVSTRRAVHP 228
            VG        G R   GE  E G          PG+    G  G++   +   +     
Sbjct: 805 EVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ--GEAGQKGDAGA 862

Query: 229 PTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQ 288
           P P+     PGP                 P    G P +A   G  G  G+P P  PP  
Sbjct: 863 PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP-- 920

Query: 289 GPPAPPRPQKARG 301
           GP     P+ ARG
Sbjct: 921 GPSGKDGPKGARG 933



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 72/303 (23%), Positives = 94/303 (31%), Gaps = 40/303 (13%)

Query: 20   GGPGRN--QTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVG----VGPL 73
            G PG++  +   G  GP  P    G      P   A S G   AP   G  G     G  
Sbjct: 777  GAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 836

Query: 74   VPDLEEGVPGARGHS-------HAIVGDPEAAHAVVVASEDSSVTCTVALHGI--PDVAV 124
             P   +G PGA+G          A    P+           + VT      G   P  A 
Sbjct: 837  GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 896

Query: 125  EVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEEL 184
                A+ +       GN G                GP  ++  +G     G     GE  
Sbjct: 897  GFPGAAGRVGPPGSNGNPGPPGPP-----------GPSGKDGPKGARGDSGPPGRAGEP- 944

Query: 185  QDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTG----PGP 240
               G +   G   E+G EPG    +G  G      ++ +R +     +R   G    PGP
Sbjct: 945  ---GLQGPAGPPGEKG-EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP 1000

Query: 241  SPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKAR 300
            S        P       P    G P      G+ G EGS     P A GPP        +
Sbjct: 1001 SGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS-----PGADGPPGRDGAAGVK 1055

Query: 301  GSR 303
            G R
Sbjct: 1056 GDR 1058



 Score = 36.2 bits (82), Expect = 0.048
 Identities = 49/196 (25%), Positives = 60/196 (30%), Gaps = 20/196 (10%)

Query: 120 PDVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVA 179
           P    ++  AS Q     ++G  GD  D +V         GP  E+  RG     GE  A
Sbjct: 87  PICPTDLATASGQPGPKGQKGEPGDIKD-IVGPKGPPGPQGPAGEQGPRGDRGDKGEKGA 145

Query: 180 VGEELQD--------------TGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRA 225
            G   +D               GP    G G     +   G      G +L         
Sbjct: 146 PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGP 205

Query: 226 VHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLP 285
           + P  P      PGP   +     P    V  P    G P      GD G  G      P
Sbjct: 206 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK-----P 260

Query: 286 PAQGPPAPPRPQKARG 301
              G   PP PQ ARG
Sbjct: 261 GKAGERGPPGPQGARG 276



 Score = 35.4 bits (80), Expect = 0.082
 Identities = 73/272 (26%), Positives = 88/272 (32%), Gaps = 68/272 (25%)

Query: 30  GGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVGPLVPDLEEGVPGARGHSH 89
           G QGPK   PG  G   A   A        R  PG    GVGP+ P  E G PG RG   
Sbjct: 465 GEQGPKGE-PGPAGPQGAPGPAGEEGKRGARGEPG----GVGPIGPPGERGAPGNRGFP- 518

Query: 90  AIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPS--AAREGNRGDATD 147
                                       G   +A       E+ PS  A  +G  GD   
Sbjct: 519 ----------------------------GQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 550

Query: 148 DVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQGREPGSGN 207
               G+             ARG+    G+    G+     GP    GE    GR PG   
Sbjct: 551 PGEPGL-----------PGARGLTGRPGDAGPQGK----VGPSGAPGE---DGR-PGPPG 591

Query: 208 TTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGH--P 265
             G  G+  V           P PK A   PG +  +     P    +       G   P
Sbjct: 592 PQGARGQPGVMGF--------PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 643

Query: 266 PSAAG-GGDSGGEGSPEPLLPPAQGPPAPPRP 296
           P  AG  G+ G +G+P P     QG P PP P
Sbjct: 644 PGPAGPAGERGEQGAPGP--SGFQGLPGPPGP 673



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 73/308 (23%), Positives = 94/308 (30%), Gaps = 38/308 (12%)

Query: 13  SPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVGP 72
           +P      GP   +   G QGP+   PG  G     PA  + + G    P   G  G   
Sbjct: 370 APGAKGEAGPTGARGPEGAQGPRGE-PGTPG--SPGPAGASGNPGTDGIPGAKGSAGAPG 426

Query: 73  LVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQ 132
           +      G PG RG        P+ A   +     +         G      E   A  Q
Sbjct: 427 IAG--APGFPGPRGPP-----GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 479

Query: 133 QPS--AAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQD---- 186
                A  EG RG   +   +G      IGP  E  A G     G+    G +       
Sbjct: 480 GAPGPAGEEGKRGARGEPGGVGP-----IGPPGERGAPGNRGFPGQDGLAGPKGAPGERG 534

Query: 187 ----TGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSP 242
                GP+   G+    G EPG     G  G+        +  V P         PGP  
Sbjct: 535 PSGLAGPKGANGDPGRPG-EPGLPGARGLTGRP--GDAGPQGKVGPSGAPGEDGRPGPPG 591

Query: 243 LRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPP-------AQGPPAPPR 295
            +     P       P    G P  A   G+ G  G+P     P       A GPP P  
Sbjct: 592 PQGARGQPGVMGFPGPKGANGEPGKA---GEKGLPGAPGLRGLPGKDGETGAAGPPGPAG 648

Query: 296 PQKARGSR 303
           P   RG +
Sbjct: 649 PAGERGEQ 656


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 85/311 (27%), Positives = 102/311 (32%), Gaps = 52/311 (16%)

Query: 19  SGGPGRNQTWVGGQGPKAP--WPGEGGWDCASPAALACSVGMGRAPPGLGPVG-VGPLVP 75
           SG PG N    G  GP  P   PGE G     PA  A + G    P   GP G VGP   
Sbjct: 242 SGSPGEN----GSPGPMGPRGLPGERGR--TGPAGAAGARGNDGQPGPAGPPGPVGPAGG 295

Query: 76  DLEEGVPGARGHSHAI-VGDPEAAHAVVVASEDSSVTCTVALHGIPDV-AVEVVVASEQQ 133
               G PGA+G +       PE A                   G P    +     S   
Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 355

Query: 134 PSAARE----GNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGP 189
           P  A      G RG        G      +GP+ +    G+    GE    GE     GP
Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGP-----LGPKGQTGEPGIAGFKGEQGPKGEP-GPAGP 409

Query: 190 RWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRA---RTGPGPSPLRSG 246
           +   G   E+G+    G   G               + PP  + A   R  PG   L   
Sbjct: 410 QGAPGPAGEEGKRGARGEPGGV------------GPIGPPGERGAPGNRGFPGQDGLAGP 457

Query: 247 HQVPS---PGSVLSPHMLFGHP--------PSAAG----GGDSGGEGSPEPLLPPAQ-GP 290
              P    P  +  P    G P        P A G     GD+G +G   P   P + G 
Sbjct: 458 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 517

Query: 291 PAPPRPQKARG 301
           P PP PQ ARG
Sbjct: 518 PGPPGPQGARG 528



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 72/275 (26%), Positives = 89/275 (32%), Gaps = 52/275 (18%)

Query: 60   RAPPG-LGPVGV-GPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALH 117
            R PPG +GP G+ GP      EG PGA G        P           D   T  V   
Sbjct: 947  RGPPGPVGPPGLTGPAGEPGREGSPGADG--------PPGRDGAAGVKGDRGETGAVGAP 998

Query: 118  GIPDVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEG 177
            G P        A        ++G+RG+A     MG        P     ARG+     +G
Sbjct: 999  GAPGPPGSPGPAGP----TGKQGDRGEAGAQGPMG--------PSGPAGARGI-----QG 1041

Query: 178  VAVGEELQDTGPRWGEGEGEEQGREPGSGNT--TGTLGKELVSQVSTRRAVHPPTPKRAR 235
                      GPR  +GE  E G     G+   TG  G       S  +    P      
Sbjct: 1042 --------PQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP 1093

Query: 236  TGP----GPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPP 291
             GP    GPS     + +P P     P    G    A   G+ G  G P        GPP
Sbjct: 1094 RGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP--------GPP 1145

Query: 292  APPRPQKA---RGSRSRRRYLWRWDSAAGVAGGAR 323
             P     A    G R +     ++  A   AGG R
Sbjct: 1146 GPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLR 1180



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 79/313 (25%), Positives = 103/313 (32%), Gaps = 67/313 (21%)

Query: 20  GGPGRNQTWVGGQGPKAPWPGEGG--WDCASPAALACSVGMGRAPPGLGPVGVGPLVPDL 77
           G PG +  + G  GP  P PGEGG   D   P       G   AP  +GP G        
Sbjct: 588 GAPGPSG-FQGLPGPPGP-PGEGGKPGDQGVP-------GEAGAPGLVGPRG-------- 630

Query: 78  EEGVPGARGHSHA--------IVGDP--EAAHAVVVASEDSSVTCTVALHGIPDVAVEVV 127
           E G PG RG   A        + G P  +        +          L G+P       
Sbjct: 631 ERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG------ 684

Query: 128 VASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVR---------AGGEGV 178
               ++ +A   G +GD  D     V E+   G   ++  RG+           A GE  
Sbjct: 685 ----ERGAAGIAGPKGDRGD-----VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG 735

Query: 179 AVGEE--LQDTGPRWGEGEGEEQGRE--------PGSGNTTGTLGKELVSQVSTRRAVHP 228
            VG        G R   GE  E G          PG+    G  G++   +   +     
Sbjct: 736 EVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ--GEAGQKGDAGA 793

Query: 229 PTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQ 288
           P P+     PGP                 P    G P +A   G  G  G+P P  PP  
Sbjct: 794 PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP-- 851

Query: 289 GPPAPPRPQKARG 301
           GP     P+ ARG
Sbjct: 852 GPSGKDGPKGARG 864



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 72/303 (23%), Positives = 94/303 (31%), Gaps = 40/303 (13%)

Query: 20  GGPGRN--QTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVG----VGPL 73
           G PG++  +   G  GP  P    G      P   A S G   AP   G  G     G  
Sbjct: 708 GAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 767

Query: 74  VPDLEEGVPGARGHS-------HAIVGDPEAAHAVVVASEDSSVTCTVALHGI--PDVAV 124
            P   +G PGA+G          A    P+           + VT      G   P  A 
Sbjct: 768 GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 827

Query: 125 EVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEEL 184
               A+ +       GN G                GP  ++  +G     G     GE  
Sbjct: 828 GFPGAAGRVGPPGSNGNPGPPGPP-----------GPSGKDGPKGARGDSGPPGRAGEP- 875

Query: 185 QDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTG----PGP 240
              G +   G   E+G EPG    +G  G      ++ +R +     +R   G    PGP
Sbjct: 876 ---GLQGPAGPPGEKG-EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP 931

Query: 241 SPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKAR 300
           S        P       P    G P      G+ G EGS     P A GPP        +
Sbjct: 932 SGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS-----PGADGPPGRDGAAGVK 986

Query: 301 GSR 303
           G R
Sbjct: 987 GDR 989



 Score = 35.4 bits (80), Expect = 0.082
 Identities = 73/272 (26%), Positives = 88/272 (32%), Gaps = 68/272 (25%)

Query: 30  GGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVGPLVPDLEEGVPGARGHSH 89
           G QGPK   PG  G   A   A        R  PG    GVGP+ P  E G PG RG   
Sbjct: 396 GEQGPKGE-PGPAGPQGAPGPAGEEGKRGARGEPG----GVGPIGPPGERGAPGNRGFP- 449

Query: 90  AIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPS--AAREGNRGDATD 147
                                       G   +A       E+ PS  A  +G  GD   
Sbjct: 450 ----------------------------GQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 481

Query: 148 DVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQGREPGSGN 207
               G+             ARG+    G+    G+     GP    GE    GR PG   
Sbjct: 482 PGEPGL-----------PGARGLTGRPGDAGPQGK----VGPSGAPGE---DGR-PGPPG 522

Query: 208 TTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGH--P 265
             G  G+  V           P PK A   PG +  +     P    +       G   P
Sbjct: 523 PQGARGQPGVMGF--------PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 574

Query: 266 PSAAG-GGDSGGEGSPEPLLPPAQGPPAPPRP 296
           P  AG  G+ G +G+P P     QG P PP P
Sbjct: 575 PGPAGPAGERGEQGAPGP--SGFQGLPGPPGP 604



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 40/156 (25%), Positives = 46/156 (29%), Gaps = 19/156 (12%)

Query: 160 GPQVEEAARGVVRAGGEGVAVGEELQD--------------TGPRWGEGEGEEQGREPGS 205
           GP  E+  RG     GE  A G   +D               GP    G G     +   
Sbjct: 57  GPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAG 116

Query: 206 GNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHP 265
           G      G +L         + P  P      PGP   +     P    V  P    G P
Sbjct: 117 GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPP 176

Query: 266 PSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARG 301
                 GD G  G      P   G   PP PQ ARG
Sbjct: 177 GPPGKPGDDGEAGK-----PGKAGERGPPGPQGARG 207



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 73/308 (23%), Positives = 94/308 (30%), Gaps = 38/308 (12%)

Query: 13  SPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVGP 72
           +P      GP   +   G QGP+   PG  G     PA  + + G    P   G  G   
Sbjct: 301 APGAKGEAGPTGARGPEGAQGPRGE-PGTPG--SPGPAGASGNPGTDGIPGAKGSAGAPG 357

Query: 73  LVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQ 132
           +      G PG RG        P+ A   +     +         G      E   A  Q
Sbjct: 358 IAG--APGFPGPRGPP-----GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 410

Query: 133 QPS--AAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQD---- 186
                A  EG RG   +   +G      IGP  E  A G     G+    G +       
Sbjct: 411 GAPGPAGEEGKRGARGEPGGVGP-----IGPPGERGAPGNRGFPGQDGLAGPKGAPGERG 465

Query: 187 ----TGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSP 242
                GP+   G+    G EPG     G  G+        +  V P         PGP  
Sbjct: 466 PSGLAGPKGANGDPGRPG-EPGLPGARGLTGRP--GDAGPQGKVGPSGAPGEDGRPGPPG 522

Query: 243 LRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPP-------AQGPPAPPR 295
            +     P       P    G P  A   G+ G  G+P     P       A GPP P  
Sbjct: 523 PQGARGQPGVMGFPGPKGANGEPGKA---GEKGLPGAPGLRGLPGKDGETGAAGPPGPAG 579

Query: 296 PQKARGSR 303
           P   RG +
Sbjct: 580 PAGERGEQ 587


>gi|117938759 GNAS complex locus XLas [Homo sapiens]
          Length = 1037

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 59/221 (26%), Positives = 80/221 (36%), Gaps = 16/221 (7%)

Query: 158 LIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELV 217
           L GP ++ +     R   E   V EE  +     G  +  E G+ P  G  +   G    
Sbjct: 332 LDGPPIKVSGAPDKRERAERPPVEEEAAEME---GAADAAEGGKVPSPGYGSPAAGAASA 388

Query: 218 SQVSTRRAVHPP------TPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLF----GHPPS 267
              +      P       TP+   +G  P+   SG     P S  +P        G  P 
Sbjct: 389 DTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPD 448

Query: 268 AAGGGDSGGEGSPE-PLLPPAQGPPAPPRPQKARGSRSRRRYLWRWDSAAGVAGGARAAL 326
           A    DSG   +P+ P  P A   P  P    A  +R+        D+ A  A  A A  
Sbjct: 449 APADPDSGA--APDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATR 506

Query: 327 SSSAAEAAAAAAAAAAARMDFLSGPSPAASAASPERRDPAR 367
           ++    AA+AA A+ A R   L  PSP   AA P    P R
Sbjct: 507 AAQVRRAASAAPASGARRKIHLRPPSPEIQAADPPTPRPTR 547



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 58/218 (26%), Positives = 81/218 (37%), Gaps = 17/218 (7%)

Query: 161 PQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEG-EEQGREPGSGNTTGTL-GKELVS 218
           P  E  A    +AG  G       ++T P   +GEG  +    PG       + G    +
Sbjct: 198 PPEEPQALRPAKAGSRG-GYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFA 256

Query: 219 QVSTRRAVH--PPTPKRARTGPGP--SPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDS 274
            V+   AV   P         PG   SP +   + PS  +  SP M    PP   G   +
Sbjct: 257 AVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPA 316

Query: 275 GGEGSPEPLLPPAQGPPAPPRPQKARGSRSRRRYLWR---WDSAAGVAGGARAALSSSAA 331
           G + +P  +  P      P  P K  G+  +R    R    + AA + G A AA      
Sbjct: 317 GVDDTPVNMDSPPIALDGP--PIKVSGAPDKRERAERPPVEEEAAEMEGAADAAEGGKVP 374

Query: 332 EAAAAAAAAAAARMDFLSGPSPAA-----SAASPERRD 364
                + AA AA  D  +  +PAA     S A+PE  D
Sbjct: 375 SPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPD 412


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 81/309 (26%), Positives = 105/309 (33%), Gaps = 76/309 (24%)

Query: 2   RASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRA 61
           R +     P   P    S GP  +    G QGP  P   +G         L   VG+   
Sbjct: 646 RGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQG---------LRGEVGLPGV 696

Query: 62  PPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPD 121
               GP+G  P  P  ++G  G RG    + G+P                    + G+P 
Sbjct: 697 KGDKGPMG--PPGPKGDQGEKGPRG----LTGEP-------------------GMRGLPG 731

Query: 122 VAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVG 181
              E        P A  +G  G A  D     H+    GP+ E+   G+    G     G
Sbjct: 732 AVGE--------PGA--KGAMGPAGPDG----HQ----GPRGEQGLTGMPGIRGPPGPSG 773

Query: 182 EELQD--TGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVH-PPTPKRARTGP 238
           +  +   TGP+  +G     GR PG     G  GK + S+ S+   V  PP P  A   P
Sbjct: 774 DPGKPGLTGPQGPQGLPGTPGR-PGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPP 832

Query: 239 GPSPLRSGHQVPSPGSVLSPHMLFGH-----------PPSAAGGGDSGGEGSPEPLLPPA 287
           GP         P       P  L GH           PP   G       G P P  PP 
Sbjct: 833 GP---------PGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG 883

Query: 288 QGPPAPPRP 296
           +G P PP P
Sbjct: 884 EGLPGPPGP 892



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 89/314 (28%), Positives = 101/314 (32%), Gaps = 68/314 (21%)

Query: 20   GGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMG--RAPPGLG--PVGVGPLVP 75
            G PG      G  GP  P   +G      P       GM   R PPG    P   G   P
Sbjct: 734  GEPGAK----GAMGPAGPDGHQG------PRGEQGLTGMPGIRGPPGPSGDPGKPGLTGP 783

Query: 76   DLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPS 135
               +G+PG  G    I G+P  A   +V SE SS+       G P               
Sbjct: 784  QGPQGLPGTPGRP-GIKGEP-GAPGKIVTSEGSSMLTVPGPPGPPGA----------MGP 831

Query: 136  AAREGNRGDATDDVVMGVHEEL-LIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEG 194
                G  G A    + G  E L L GP      RG       G          GPR   G
Sbjct: 832  PGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPG--------PPGPRGPPG 883

Query: 195  EGEEQGREPGSGNTTGTLGKELVSQVSTRRAVH-PPTPKRARTGPGPSPLRSGHQVPS-- 251
            EG      PG     G+      + +S       PP PK  +  PGP     GHQ     
Sbjct: 884  EGL-----PGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPR----GHQGEQGL 934

Query: 252  PGSVLSPHMLFG-------HPPSAAGG-GDSGGEGSPEPLLPPA-------------QGP 290
            PG   S    FG        PP   G  GD G  G P  L  P+              GP
Sbjct: 935  PGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGP 994

Query: 291  PAPPRPQKARGSRS 304
            P PP P    GS S
Sbjct: 995  PGPPGPPGPPGSIS 1008



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 50/165 (30%), Positives = 61/165 (36%), Gaps = 37/165 (22%)

Query: 169  GVVRAGGE-GVAVGEELQ---DTGPRWGEGEGEEQGREPGSGNTTGTLG---------KE 215
            G + AGG  G A G+      D GP  G G   E G   G+G   G LG          E
Sbjct: 1319 GSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNG---GLLGADFAGDLDYNE 1375

Query: 216  LVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPG---------SVLSPHMLF---- 262
            L  +VS            A T  GP P + G Q P PG         +V +  M F    
Sbjct: 1376 LAVRVSESMQRQGLLQGMAYTVQGP-PGQPGPQGP-PGISKVFSAYSNVTADLMDFFQTY 1433

Query: 263  ----GHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGSR 303
                G P      G  G +G   P  PP  G P PP P+  +G +
Sbjct: 1434 GAIQGPPGQKGEMGTPGPKGDRGPAGPP--GHPGPPGPRGHKGEK 1476



 Score = 29.3 bits (64), Expect = 5.9
 Identities = 35/128 (27%), Positives = 41/128 (32%), Gaps = 20/128 (15%)

Query: 186  DTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRS 245
            D GP    G   EQG    S + + + G  L           P   K     PG   + S
Sbjct: 919  DQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPS 978

Query: 246  GHQVPSPGSVLSPHMLFGHP-----PSAAGGGDSGGE------------GSPEPLLPPAQ 288
            G   PS G   S   + G P     P   G   S G+             S    L   Q
Sbjct: 979  G---PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQ 1035

Query: 289  GPPAPPRP 296
            GPP PP P
Sbjct: 1036 GPPGPPGP 1043


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 75/290 (25%), Positives = 99/290 (34%), Gaps = 70/290 (24%)

Query: 30   GGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVGPLVPDLEEGVPGARGHS- 88
            G +GP  P    G      PA  A  +G+   P   GP G     P  E+G PG +G   
Sbjct: 1075 GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPG-----PAGEKGAPGEKGPQG 1129

Query: 89   -------HAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAAREGN 141
                      VG P  A  V    ED                        +     ++G+
Sbjct: 1130 PAGRDGLQGPVGLPGPAGPVGPPGEDGD--------------------KGEIGEPGQKGS 1169

Query: 142  RGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEE-----LQDTGPRWGEGEG 196
            +GD  +    G       GPQ      G   A GE    G++       D GPR   G  
Sbjct: 1170 KGDKGEQGPPGP-----TGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPP 1224

Query: 197  EEQGRE-----PGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPS 251
               G +     PG    TG +G+           + PP P   R GP  +P   G Q P 
Sbjct: 1225 GPVGLQGLPGPPGEKGETGDVGQ-----------MGPPGPPGPR-GPSGAPGADGPQGP- 1271

Query: 252  PGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARG 301
            PG +       G+P +    G+ G  G  EP LP   GPP P   +  +G
Sbjct: 1272 PGGI-------GNPGAVGEKGEPGEAG--EPGLPGEGGPPGPKGERGEKG 1312



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 76/293 (25%), Positives = 95/293 (32%), Gaps = 42/293 (14%)

Query: 30   GGQGPKAPWPGEGG--WDCASPAALACSVGMG-RAPPG-LGPVG-VGPLVPDLEEGVPGA 84
            G  GP  P PGE G   +   P         G + PPG  GP G +G   P   +G PG 
Sbjct: 1144 GPAGPVGP-PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGP 1202

Query: 85   RGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAAREGNRGD 144
            RG         +                 V L G+P                   G +G+
Sbjct: 1203 RGQQGLFGQKGDEGPRGFPGPPGP-----VGLQGLP----------------GPPGEKGE 1241

Query: 145  ATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQGREPG 204
              D   MG       GP+    A G     G    +G      G +   GE  E G  PG
Sbjct: 1242 TGDVGQMGPPGPP--GPRGPSGAPGADGPQGPPGGIGNP-GAVGEKGEPGEAGEPGL-PG 1297

Query: 205  SGNTTGTLGKE-LVSQVSTRRAVHPPTPKRARTGPGP--SPLRSGHQV-PSPGSVLSPHM 260
             G   G  G+     +     A  PP PK      GP  SP   G    P P     P  
Sbjct: 1298 EGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAG 1357

Query: 261  LFGHPPSAAGGGDSGGEGSPEPLLPPA-------QGPPAPPRPQKARGSRSRR 306
              G P      G+ G  GSP P   P        +GPP P  P+  +G +  +
Sbjct: 1358 QDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAK 1410



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 77/294 (26%), Positives = 94/294 (31%), Gaps = 47/294 (15%)

Query: 21   GPGRNQTWVGGQGPKAPWPGEGGWDC--ASPAALACSVGMGRAPPGLGPVGVGPLVPDLE 78
            GP   Q   G  GPK P PG  G D     P     +   G+  P   P  VGP  P  E
Sbjct: 949  GPNGPQGPTGFPGPKGP-PGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGE 1007

Query: 79   EGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSA-- 136
             G  G RGH     G P                      G+P +A +     +  P+   
Sbjct: 1008 TGPMGERGHP----GPPGPPGE----------------QGLPGLAGKEGTKGDPGPAGLP 1047

Query: 137  ---AREGNRGDATDDVVMGVHEEL-LIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWG 192
                  G RG   D  + G    L L G +      G   + GE    G      GP   
Sbjct: 1048 GKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGA----AGPIGI 1103

Query: 193  EGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSP 252
             G    QG  PG     G  G++     + R  +  P       GP   P   G +    
Sbjct: 1104 PGRPGPQG-PPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDK---- 1158

Query: 253  GSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGSRSRR 306
            G +       G P      GD G +G P P  P  QGP   P P  A G    R
Sbjct: 1159 GEI-------GEPGQKGSKGDKGEQGPPGPTGP--QGPIGQPGPSGADGEPGPR 1203



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 78/307 (25%), Positives = 106/307 (34%), Gaps = 63/307 (20%)

Query: 6   SSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGL 65
           S +  I   + L   GP       G  GP  P PG GG              +   P  +
Sbjct: 544 SQAQAILQQARLALRGPAGPMGLTGRPGPVGP-PGSGG--------------LKGEPGDV 588

Query: 66  GPVGV-GPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAV 124
           GP G  G   P    G PG RG + +     + A  +   +          L G+P    
Sbjct: 589 GPQGPRGVQGPPGPAGKPGRRGRAGS-----DGARGMPGQTGPKGDRGFDGLAGLPG--- 640

Query: 125 EVVVASEQQPSA-----AREGNRGDATDDVVMGVHEEL----LIGPQVEEAARGVVRAGG 175
           E     +  PS        +G RGD  +    G+  E     L+GP+      G     G
Sbjct: 641 EKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTG 700

Query: 176 EGVAVGEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRAR 235
                G +  + GP+   G   +QG  PG+    G  G           A+ PP  K   
Sbjct: 701 MDGQPGPK-GNVGPQGEPGPPGQQGN-PGAQGLPGPQG-----------AIGPPGEK--- 744

Query: 236 TGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPR 295
            GP   P   G     PG+   P    GHP      G+ GG+G P P     QGP   P 
Sbjct: 745 -GPLGKPGLPG----MPGADGPP----GHPGKEGPPGEKGGQGPPGP-----QGPIGYPG 790

Query: 296 PQKARGS 302
           P+  +G+
Sbjct: 791 PRGVKGA 797



 Score = 33.1 bits (74), Expect = 0.41
 Identities = 73/287 (25%), Positives = 100/287 (34%), Gaps = 63/287 (21%)

Query: 33  GPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVGPLVPDLEEGVPGARGHSHAIV 92
           GPK P PG  G     P  +    GM   P   G VG     P  E G PG +G+  A  
Sbjct: 685 GPKGP-PGPPG-----PPGVT---GMDGQPGPKGNVG-----PQGEPGPPGQQGNPGA-Q 729

Query: 93  GDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAAREGN----------- 141
           G P    A+    E   +     L G+P          ++ P   + G            
Sbjct: 730 GLPGPQGAIGPPGEKGPLG-KPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGY 788

Query: 142 ---RGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGE--ELQDTGPRWGEGEG 196
              RG    D + G     L G + E+   G     G+    G+  E+   GPR  +G  
Sbjct: 789 PGPRGVKGADGIRG-----LKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPE 843

Query: 197 EEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVL 256
             +GR   +G+  G LG               P  ++ + G    P   G Q P  GS+ 
Sbjct: 844 GPKGRGGPNGDP-GPLG---------------PPGEKGKLGVPGLPGYPGRQGPK-GSI- 885

Query: 257 SPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGSR 303
                 G P      G+ GG G+P    P  +G   P  P+  RG R
Sbjct: 886 ------GFPGFPGANGEKGGRGTPGK--PGPRGQRGPTGPRGERGPR 924



 Score = 32.0 bits (71), Expect = 0.91
 Identities = 49/184 (26%), Positives = 64/184 (34%), Gaps = 47/184 (25%)

Query: 160  GPQVEEAARGVV-RAGGEGVAVGEELQDTGPRWGEGEGEEQGRE--PGSGNTTGTLGKEL 216
            GP+ E   RG+  + G +G + G+     GP    G    QG    PG     G  GK+ 
Sbjct: 916  GPRGERGPRGITGKPGPKGNSGGDG--PAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDG 973

Query: 217  VSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHP----------- 265
            +     +R     T  + +TGP   P   G Q P+  +   P    GHP           
Sbjct: 974  LPGHPGQRG---ETGFQGKTGPPGPPGVVGPQGPTGET--GPMGERGHPGPPGPPGEQGL 1028

Query: 266  PSAAGG----GDSGGEGSPEPLLPPA----------------------QGPPAPPRPQKA 299
            P  AG     GD G  G P    PP                       +GPP PP P  +
Sbjct: 1029 PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGS 1088

Query: 300  RGSR 303
             G R
Sbjct: 1089 PGER 1092



 Score = 32.0 bits (71), Expect = 0.91
 Identities = 78/303 (25%), Positives = 98/303 (32%), Gaps = 49/303 (16%)

Query: 30   GGQGPKAPWPGEGGWDCASPAALACSVGMGRA-PPGLGPVGVGPLVPDLEEGVPGARGHS 88
            G  GP+ P  G G     +P A+      G A  PGL   G GP  P  E G  G  G S
Sbjct: 1264 GADGPQGPPGGIG-----NPGAVGEKGEPGEAGEPGLPGEG-GPPGPKGERGEKGESGPS 1317

Query: 89   HAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAAREGNRGDATDD 148
             A    P                  V   G P    E   A +  P     G++GD  + 
Sbjct: 1318 GA--AGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPP----GDKGDDGEP 1371

Query: 149  VVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQGREPGSGNT 208
               G       GP  E    G     G     G E +  G +  +GE   +G  PG    
Sbjct: 1372 GQTGSP-----GPTGEPGPSGPPGKRGPPGPAGPEGRQ-GEKGAKGEAGLEG-PPGKTGP 1424

Query: 209  TGTLGKELVSQVSTRRAVHPPTPKRARTG-PGPS--PLRSGHQ-VPSPGSVLSPHMLFGH 264
             G  G          R +  P  ++   G PGP   P   G   +P       P    GH
Sbjct: 1425 IGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGH 1484

Query: 265  P----------------------PSAAGG--GDSGGEGSPEPLLPPAQ-GPPAPPRPQKA 299
            P                      P  + G  G+ G  G   P+ PP   G P PP P+ A
Sbjct: 1485 PGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGA 1544

Query: 300  RGS 302
            +GS
Sbjct: 1545 KGS 1547


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 97/359 (27%), Positives = 121/359 (33%), Gaps = 62/359 (17%)

Query: 20  GGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVGPLVPDLEE 79
           G PG +   +G +GP  P PG+ G D    A      G  R PPG  P G   L      
Sbjct: 209 GEPGASGP-MGPRGPPGP-PGKNGDD--GEAGKPGRPGE-RGPPG--PQGARGLPGTA-- 259

Query: 80  GVPGARGHS-----HAIVGD--PEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQ 132
           G+PG +GH          GD  P        +  ++     +   G+P    E       
Sbjct: 260 GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG---ERGRPGAP 316

Query: 133 QPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWG 192
            P+ AR GN G        G       GP       G V A GE           GPR  
Sbjct: 317 GPAGAR-GNDGATGAAGPPGP-----TGPAGPPGFPGAVGAKGEA-------GPQGPRGS 363

Query: 193 EGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPG--PSPLRSGHQVP 250
           EG    +G EPG     G  G           A   P  K A   PG   +P   G + P
Sbjct: 364 EGPQGVRG-EPGPPGPAGAAGP-----AGNPGADGQPGAKGANGAPGIAGAPGFPGARGP 417

Query: 251 S----PGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGSRSRR 306
           S    PG    P    G P +    GD+G +G P P+    QGPP P   +  RG+R   
Sbjct: 418 SGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV--GVQGPPGPAGEEGKRGARGE- 474

Query: 307 RYLWRWDSAAGVAG-----GARAALSSSAAEAAAAAAAAAAARMDFLSGPSPAASAASP 360
                     G+ G     G   +     A+  A     A  R      P PA    SP
Sbjct: 475 ------PGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGER----GSPGPAGPKGSP 523



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 104/377 (27%), Positives = 125/377 (33%), Gaps = 55/377 (14%)

Query: 13  SPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGV-G 71
           +P +  + GP       G QGP  P PG  G +   P A   S G   A    GPVGV G
Sbjct: 408 APGFPGARGPS------GPQGPGGP-PGPKG-NSGEPGAPG-SKGDTGAKGEPGPVGVQG 458

Query: 72  PLVPDLEEGVPGARGHSH--AIVGDP-----EAAHAVVVASEDSSVTCTVALHGIPDVAV 124
           P  P  EEG  GARG      + G P       +     A   +         G P  A 
Sbjct: 459 PPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG 518

Query: 125 EVVVASEQ-QPSAAR-------EGNRGDATDDVVMG----VHEELLIGPQVEEAARGVVR 172
                 E  +P  A         G+ G    D   G      ++   GP     ARG  +
Sbjct: 519 PKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG--Q 576

Query: 173 AGGEGVAVGEELQDTGPRWGEGEGEEQGRE--PGSGNTTGTLGKELVSQVSTRRAVHPPT 230
           AG  G          GP+   GE  + G    PG     G  GK+  +          P 
Sbjct: 577 AGVMGFP--------GPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPA 628

Query: 231 PKRARTGPGPSPLRSGHQVPS--PGSVLSPHMLFGHPPSAAGGGDSGGEGSPE-PLLPPA 287
            +R   GP  SP   G   P+  PG    P    G P      G SG  G    P     
Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQ-GVPGDLGAPGPSGARGERGFPGERGV 687

Query: 288 QGPPAPPRPQKARGSRSRRRYLWRWDSAAGVAGGARAALSSSAAEAAAAAAAAAAARMDF 347
           QGPP P  P+ A G+          D A G AG   A  S  A           AA    
Sbjct: 688 QGPPGPAGPRGANGAPGN-------DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAG--- 737

Query: 348 LSGPSPAASAASPERRD 364
           L GP      A P+  D
Sbjct: 738 LPGPKGDRGDAGPKGAD 754



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 88/359 (24%), Positives = 107/359 (29%), Gaps = 78/359 (21%)

Query: 21  GPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVGPLVPDLEEG 80
           GP       G QGP  P         A PA      G   +P   G  G  P  P  E G
Sbjct: 608 GPAGKDGEAGAQGPPGP---------AGPAGERGEQGPAGSPGFQGLPG--PAGPPGEAG 656

Query: 81  VPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAAREG 140
            PG +G    + GD  A        E           G P    E  V     P+  R  
Sbjct: 657 KPGEQG----VPGDLGAPGPSGARGE----------RGFPG---ERGVQGPPGPAGPRGA 699

Query: 141 NRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVG-----EELQDTGPRWGEGE 195
           N     D            G    + A G+    GE  A G      +  D GP+  +G 
Sbjct: 700 NGAPGNDGAKGDAGAP---GAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS 756

Query: 196 GEEQGRE--------PGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGH 247
             + G          PG     G  G+   S         P  P  AR  PG    R   
Sbjct: 757 PGKDGVRGLTGPIGPPGPAGAPGDKGESGPSG--------PAGPTGARGAPGD---RGEP 805

Query: 248 QVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGSRSRRR 307
             P P     P    G P +    GD+G +G   P  P   GP  PP P    G      
Sbjct: 806 GPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGP--PGPAGPAGPPGPIGNVG------ 857

Query: 308 YLWRWDSAAGVAGGARAALSSSAAEAAAAAAAAAAARMDFLSGPSPAASAASPERRDPA 366
                      A GA+ A  S+    A     AA      +  P P+ +A  P    PA
Sbjct: 858 -----------APGAKGARGSAGPPGATGFPGAAGR----VGPPGPSGNAGPPGPPGPA 901



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 84/287 (29%), Positives = 95/287 (33%), Gaps = 71/287 (24%)

Query: 31   GQGPKAPWPGEGGWDCASPAALACSVGMG-RAPPG-LGPVGV-GPLVPDLEEGVPGARGH 87
            GQ  +  +PG  G     P     S   G R PPG +GP G+ GP      EG PGA G 
Sbjct: 965  GQRGERGFPGLPG-PSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEG- 1022

Query: 88   SHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAAREGNRGDATD 147
            S    G P A         D   T      G P        A      A + G+RG+   
Sbjct: 1023 SPGRDGSPGA-------KGDRGETGPAGPPGAPGAPG----APGPVGPAGKSGDRGET-- 1069

Query: 148  DVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQGREPGSGN 207
                        GP       G V A G            GPR  +GE  EQG + G   
Sbjct: 1070 ------------GPAGPAGPVGPVGARGPA-------GPQGPRGDKGETGEQG-DRGIKG 1109

Query: 208  TTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPS 267
              G  G +            PP       GP  SP   G Q PS  S   P    G P S
Sbjct: 1110 HRGFSGLQ-----------GPP-------GPPGSP---GEQGPSGAS--GPAGPRGPPGS 1146

Query: 268  AAGGGDSGGEGSPEPLLPPAQ----------GPPAPPRPQKARGSRS 304
            A   G  G  G P P+ PP            GPP PP P    G  S
Sbjct: 1147 AGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPS 1193



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 84/314 (26%), Positives = 104/314 (33%), Gaps = 69/314 (21%)

Query: 21  GPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGV---------- 70
           GP  ++   G +G   P PG  G   A PA    + G   A    G  G+          
Sbjct: 359 GPRGSEGPQGVRGEPGP-PGPAG--AAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415

Query: 71  GPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVAS 130
           GP  P    G PG +G+S    G+P A  +             V + G P  A E     
Sbjct: 416 GPSGPQGPGGPPGPKGNS----GEPGAPGSKGDTGAKGEPG-PVGVQGPPGPAGE----- 465

Query: 131 EQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVR-AGGEGVAVGE----ELQ 185
                   EG RG   +    G     L GP  E    G     G +GVA  +    E  
Sbjct: 466 --------EGKRGARGEPGPTG-----LPGPPGERGGPGSRGFPGADGVAGPKGPAGERG 512

Query: 186 DTGPRWGEGEGEEQGRE-----PGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGP 240
             GP   +G   E GR      PG+   TG+ G               P  K    GP  
Sbjct: 513 SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSP------------GPDGKTGPPGPAG 560

Query: 241 SPLRSGHQVPSPGSVLSPHMLFGHPPSAAG----GGDSGGEGSPEPLLPP-------AQG 289
              R G   P      +  M F  P  AAG     G+ G  G P  + P        AQG
Sbjct: 561 QDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQG 620

Query: 290 PPAPPRPQKARGSR 303
           PP P  P   RG +
Sbjct: 621 PPGPAGPAGERGEQ 634



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 84/314 (26%), Positives = 99/314 (31%), Gaps = 69/314 (21%)

Query: 21   GPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVG-VGPLVPDLEE 79
            GP   +   G +G   P PG  G+  A P       G    P   G  G  GP  P    
Sbjct: 791  GPTGARGAPGDRGEPGP-PGPAGF--AGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPA 847

Query: 80   GVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAARE 139
            G PG  G+    VG P A  A   A    +        G P  A  V       PS    
Sbjct: 848  GPPGPIGN----VGAPGAKGARGSAGPPGAT-------GFPGAAGRV---GPPGPS---- 889

Query: 140  GNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQ 199
            GN G                GP  +E  +G     G     GE     GP    G   E+
Sbjct: 890  GNAGPPGPP-----------GPAGKEGGKGPRGETGPAGRPGE----VGPPGPPGPAGEK 934

Query: 200  GREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTG----PGPSPLRSGHQVPS---- 251
            G  PG+    G  G      ++ +R V     +R   G    PGPS    G Q PS    
Sbjct: 935  G-SPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSG-EPGKQGPSGASG 992

Query: 252  ---PGSVLSPHMLFGHPPSAAGGGDSGGEGSP-------------------EPLLPPAQG 289
               P   + P  L G P  +   G  G EGSP                    P  P A G
Sbjct: 993  ERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPG 1052

Query: 290  PPAPPRPQKARGSR 303
             P P  P    G R
Sbjct: 1053 APGPVGPAGKSGDR 1066



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 84/302 (27%), Positives = 104/302 (34%), Gaps = 42/302 (13%)

Query: 21  GPGRNQTWVGGQGPKAPWPGEGG--WDCASPAALACSVGMG-RAPPGL-GPVGV-GPLVP 75
           GP  +  + G  GP  P PGE G   +   P  L      G R   G  G  GV GP  P
Sbjct: 635 GPAGSPGFQGLPGPAGP-PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGP 693

Query: 76  DLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDV--AVEVVVASEQQ 133
               G  GA G+  A  GD  A  A    S+ +       L G+P    A  +      +
Sbjct: 694 AGPRGANGAPGNDGA-KGDAGAPGAP--GSQGAP-----GLQGMPGERGAAGLPGPKGDR 745

Query: 134 PSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGE 193
             A  +G  G    D V G+     IGP     A G     G     G     TG R   
Sbjct: 746 GDAGPKGADGSPGKDGVRGLTGP--IGPPGPAGAPGDKGESGPSGPAGP----TGARGAP 799

Query: 194 GEGEEQGRE--------PGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRS 245
           G+  E G          PG+    G  G+        +    PP P      PGP     
Sbjct: 800 GDRGEPGPPGPAGFAGPPGADGQPGAKGEP--GDAGAKGDAGPPGPAGPAGPPGPIG--- 854

Query: 246 GHQVPSPGSVLSPHMLFGHPPSAAG-GGDSGGEGSPEPLLPPAQGPPAPPRPQKARGSRS 304
              V +PG+  +       PP A G  G +G  G P P      GPP PP P    G + 
Sbjct: 855 --NVGAPGAKGARGS--AGPPGATGFPGAAGRVGPPGP--SGNAGPPGPPGPAGKEGGKG 908

Query: 305 RR 306
            R
Sbjct: 909 PR 910



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 38/142 (26%), Positives = 44/142 (30%), Gaps = 29/142 (20%)

Query: 186 DTGPRWGEGEGEEQGRE--PGSGNTTGT-----------LGKELVSQVSTRRAVHPPTPK 232
           DTGPR   G     GR+  PG     G            LG     Q+S     +     
Sbjct: 116 DTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYG---YDEKST 172

Query: 233 RARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQ---- 288
              + PGP        +P P     P    G P      G SG  G   P  PP +    
Sbjct: 173 GGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDD 232

Query: 289 ---------GPPAPPRPQKARG 301
                    G   PP PQ ARG
Sbjct: 233 GEAGKPGRPGERGPPGPQGARG 254


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 87/294 (29%), Positives = 103/294 (35%), Gaps = 50/294 (17%)

Query: 21  GPGRNQTWVGGQGPKAPWPGEGGW---DCASPAALACSVGMGRAP--PGL-GPVGVGPLV 74
           GP   Q   G QG   P PG+ G    +      L  + G G AP  PGL GP G+G   
Sbjct: 182 GPPGFQGEPGPQGEPGP-PGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPG 240

Query: 75  PDLEEGVPGARGHSHAI-VGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQ 133
            D   G PG +G S    V  P      V       V       G+P  A    +   Q 
Sbjct: 241 LDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV----GVPGAAG---LPGPQG 293

Query: 134 PSAAR--EGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRW 191
           PS A+   G RG        G     L GP+ +    GV    G+    GE+  + G + 
Sbjct: 294 PSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGED-GEPGEQG 352

Query: 192 GEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPS 251
            +G G   G  PGS    G  G              PP PK    GPG  P      VP 
Sbjct: 353 PQGLGGPPGL-PGSAGLPGRRG--------------PPGPK-GEAGPGGPP-----GVPG 391

Query: 252 PGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGSRSR 305
                 P  L G P      G  G  G     LP A GPP P  P+   G   R
Sbjct: 392 IRGDQGPSGLAGKP------GVPGERG-----LPGAHGPPGPTGPKGEPGFTGR 434



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 91/345 (26%), Positives = 112/345 (32%), Gaps = 42/345 (12%)

Query: 30  GGQGPKAPWPGEGGWDCASPAALACSVGMG--------RAPPGL-GPVGVGPLVPDLEEG 80
           G  GPK P PG  G      A L    G          R PPGL GP G G        G
Sbjct: 267 GAVGPKGP-PGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGM------PG 319

Query: 81  VPGARGHSHAIVGDPEAAHAVVVASEDSSV--TCTVALHGIPDVAVEVVVASEQQPSAAR 138
           +PG +G      G P          ED          L G P +     +   + P   +
Sbjct: 320 LPGPKG-DRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPK 378

Query: 139 EGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEE 198
            G  G      V G+  +   GP       GV    G   A G      GP   +GE   
Sbjct: 379 -GEAGPGGPPGVPGIRGDQ--GPSGLAGKPGVPGERGLPGAHGPP----GPTGPKGEPGF 431

Query: 199 QGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGP----GPSPLRSGHQVPS--- 251
            GR PG     G LG++    +  +  +  P+      GP    GP  L      P    
Sbjct: 432 TGR-PGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPG 490

Query: 252 -PGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGSRSRRRYLW 310
            PG   +     G P +A   G  G  GSP    PP  GPP PP P  A G+        
Sbjct: 491 PPGEGRA-----GEPGTAGPTGPPGVPGSPGITGPP--GPPGPPGPPGAPGAFDETGIAG 543

Query: 311 RWDSAAGVAGGARAALSSSAAEAAAAAAAAAAARMDFLSGPSPAA 355
                 GV G                +A A  A    L+ P PA+
Sbjct: 544 LHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPAS 588



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 39/137 (28%), Positives = 46/137 (33%), Gaps = 32/137 (23%)

Query: 188 GPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGH 247
           GP   +GE   QG EPG     G  G   V Q        P  P     G  P P     
Sbjct: 182 GPPGFQGEPGPQG-EPGPPGDRGLKGDNGVGQ--------PGLPGAPGQGGAPGP----P 228

Query: 248 QVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPL------------------LPPAQG 289
            +P P  +  P  L G P +    G+SG  G P P                   +P A G
Sbjct: 229 GLPGPAGLGKPG-LDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAG 287

Query: 290 PPAPPRPQKARGSRSRR 306
            P P  P  A+G    R
Sbjct: 288 LPGPQGPSGAKGEPGTR 304


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 52/171 (30%), Positives = 64/171 (37%), Gaps = 22/171 (12%)

Query: 193  EGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRART-GPGPSPLRSGHQVPS 251
            EGE  +  + P S          L   V   +    PT K+    GPG   ++  H  P 
Sbjct: 1215 EGEARKPAKPPVSPKPV------LTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPP 1268

Query: 252  PGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPA----PPRPQKARGSRSRRR 307
            P S   P       P  A  G   G   P P   PA+ PPA    PP    + G+     
Sbjct: 1269 PVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGA----- 1323

Query: 308  YLWRWDSAAGVAGGARAA-LSSSAAEAAAAAAAAAAARMDFLSGPSPAASA 357
                   A   + GA A  + +    AAAAAAAAAAA      G SP  SA
Sbjct: 1324 -----SPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSA 1369


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 87/316 (27%), Positives = 106/316 (33%), Gaps = 66/316 (20%)

Query: 12  PSPSYLHSGGPGRN-----QTWVGGQGPKAPWPG----EGGWDCASPAALACSVGM--GR 60
           P+ S   +G PG+      Q   G QGP  P PG     GG     PA +  + G+   R
Sbjct: 355 PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGP-PGINGSPGGKGEMGPAGIPGAPGLMGAR 413

Query: 61  APPGLGPV--------GVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTC 112
            PPG            G G    +  +G PG RG      G P    A     +D S   
Sbjct: 414 GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE-RGEAGIPGVPGAKGEDGKDGSPGE 472

Query: 113 TVALHGIPDVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVR 172
             A +G+P  A E              G RG A  + + G       GP  E  A G   
Sbjct: 473 PGA-NGLPGAAGE----------RGAPGFRGPAGPNGIPGEK-----GPAGERGAPGPAG 516

Query: 173 AGGEGVAVGEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPK 232
             G     G +    GP      G   G  PGS    G  G    SQ  + R   PP P 
Sbjct: 517 PRGAAGEPGRDGVPGGPGMRGMPGSPGG--PGSDGKPGPPG----SQGESGRP-GPPGPS 569

Query: 233 RARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPA----- 287
             R  PG          P P          G+  +    G+ GG G P P  PP      
Sbjct: 570 GPRGQPGVMGF------PGPK---------GNDGAPGKNGERGGPGGPGPQGPPGKNGET 614

Query: 288 --QGPPAPPRPQKARG 301
             QGPP P  P   +G
Sbjct: 615 GPQGPPGPTGPGGDKG 630



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 84/319 (26%), Positives = 105/319 (32%), Gaps = 74/319 (23%)

Query: 18  HSGGPGRN--QTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVG----VG 71
           + G PG+N  +   GG GP+ P PG+ G             G    P   GP G     G
Sbjct: 586 NDGAPGKNGERGGPGGPGPQGP-PGKNG-----------ETGPQGPPGPTGPGGDKGDTG 633

Query: 72  PLVPDLEEGVPGARGH--SHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVA 129
           P  P   +G+PG  G    +   G+P                      G P    +    
Sbjct: 634 PPGPQGLQGLPGTGGPPGENGKPGEPGPKG-------------DAGAPGAPGGKGDAGAP 680

Query: 130 SEQQPS--AAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEE-LQD 186
            E+ P   A   G RG A              GP   E  +G     G   A G   LQ 
Sbjct: 681 GERGPPGLAGAPGLRGGA--------------GPPGPEGGKGAAGPPGPPGAAGTPGLQG 726

Query: 187 T-GPRWGEGEGEEQGR--EPGSGNTTGTLGKELVSQVSTRRAVHPPTP--KRARTGPGPS 241
             G R G G    +G   EPG     G  GK+          + PP P  +    G G +
Sbjct: 727 MPGERGGLGSPGPKGDKGEPGGPGADGVPGKD--GPRGPTGPIGPPGPAGQPGDKGEGGA 784

Query: 242 PLRSGHQVP--SPGS--VLSPHMLFGHPPSAAGGGDSGG-----------EGSPEPLLPP 286
           P   G   P  SPG      P    G P +    G+ GG           EG P  +  P
Sbjct: 785 PGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP 844

Query: 287 --AQGPPAPPRPQKARGSR 303
               GP  PP PQ  +G R
Sbjct: 845 PGGSGPAGPPGPQGVKGER 863



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 76/282 (26%), Positives = 92/282 (32%), Gaps = 48/282 (17%)

Query: 30  GGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVGPLVPDLEEGVPGARGHSH 89
           G  GP  P PG  G+   SP A    VG   +P   G  G        + G PG +GH+ 
Sbjct: 330 GQPGPPGP-PGTAGFP-GSPGAKG-EVGPAGSPGSNGAPG--------QRGEPGPQGHAG 378

Query: 90  A--------IVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAAR--E 139
           A        I G P     +  A             GIP     +       P+ A    
Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPA-------------GIPGAPGLMGARGPPGPAGANGAP 425

Query: 140 GNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQ 199
           G RG A +    G   E   GP+ E    G+    G   A GE+ +D  P    GE    
Sbjct: 426 GLRGGAGEPGKNGAKGEP--GPRGERGEAGIPGVPG---AKGEDGKDGSP----GEPGAN 476

Query: 200 GREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPH 259
           G  PG+    G  G                 P   R  PGP+  R     P    V    
Sbjct: 477 GL-PGAAGERGAPGFR--GPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533

Query: 260 MLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARG 301
            + G P S  G G  G  G P        G P PP P   RG
Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGS--QGESGRPGPPGPSGPRG 573



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 81/322 (25%), Positives = 105/322 (32%), Gaps = 69/322 (21%)

Query: 20   GGPGRNQTWVGGQGPKAPW--PGEGGWDCASPAALACSVGMGRAPPGLGPVGVGPLVPDL 77
            G PG N    G  GP  P   PG+ G     P   A + G   +P   GP G        
Sbjct: 882  GPPGSN----GNPGPPGPSGSPGKDG-----PPGPAGNTGAPGSPGVSGPKG-------- 924

Query: 78   EEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAA 137
            + G PG +G S    G P A   + +A     +T    L G P +          + S  
Sbjct: 925  DAGQPGEKG-SPGAQGPPGAPGPLGIAG----ITGARGLAGPPGMP-------GPRGSPG 972

Query: 138  REGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQD-----TGPRWG 192
             +G +G++      G+  E   GP   +   G+    GE    G    D      G   G
Sbjct: 973  PQGVKGESGKPGANGLSGER--GPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG 1030

Query: 193  EGEGEEQGR--------EPGSGNTTGTLGKELV-SQVSTRRAVHPPTPKRARTGPGPSPL 243
            +G+  E G          PG     G  GK     +         P P  +R  PGP   
Sbjct: 1031 KGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGP 1090

Query: 244  RS--GHQVPSPGSVLSPHMLFGHPPSAAGG----GDSGGEGSPEPLLPPA---------- 287
            R   G       + +  H  F   P A G     G  G  GSP P  P            
Sbjct: 1091 RGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGK 1150

Query: 288  ------QGPPAPPRPQKARGSR 303
                   GP  PP P+  RG R
Sbjct: 1151 DGTSGHPGPIGPPGPRGNRGER 1172



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 93/321 (28%), Positives = 108/321 (33%), Gaps = 59/321 (18%)

Query: 20   GGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGV-----GPLV 74
            G PG+N    GG+G +   PGE G +   P       G G A P  GP GV      P  
Sbjct: 813  GAPGQNGE-PGGKGERGA-PGEKG-EGGPPGVAGPPGGSGPAGPP-GPQGVKGERGSPGG 868

Query: 75   PDLEEGVPGARG-----HSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVA 129
            P    G PGARG      S+   G P  + +            T A  G P V       
Sbjct: 869  PGAA-GFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGA-PGSPGV------- 919

Query: 130  SEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGP 189
            S  +  A + G +G        G    L I       ARG+  AG  G+         GP
Sbjct: 920  SGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGIT--GARGL--AGPPGMP--------GP 967

Query: 190  RWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQV 249
            R            PG     G  GK   + +S  R    P       G    P R G+  
Sbjct: 968  RGS----------PGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGN-- 1015

Query: 250  PSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGSRSRRRYL 309
              PGS   P    G   S  G GD G  GSP    P A G P PP P    G    R   
Sbjct: 1016 --PGSDGLP----GRDGSPGGKGDRGENGSPGA--PGAPGHPGPPGPVGPAGKSGDRGE- 1066

Query: 310  WRWDSAAGVAGGARAALSSSA 330
                  AG AG    A S  A
Sbjct: 1067 ---SGPAGPAGAPGPAGSRGA 1084



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 58/218 (26%), Positives = 76/218 (34%), Gaps = 32/218 (14%)

Query: 177 GVAVGEELQDTGPRWGEGEGEEQGRE--PGSGNTTGTLGKELVSQVSTRRAVHPPTPKRA 234
           GVAVG      GP    G     G    PGS  + G  G     +        PP P  A
Sbjct: 163 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPP--GEPGQAGPSGPPGPPGA 220

Query: 235 RTGPGPS--------PLRSGHQ-VPSPGSVLSPHMLFGHPPSAAG------GGDSGGEGS 279
               GP+        P R G + +P P  +  P  + G P            G+ G  G+
Sbjct: 221 IGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGA 280

Query: 280 P----EPLLPPAQGPPAPPRPQKARGSRSRRRYLWRWDSAAGVAG--GARAALSSSAAEA 333
           P    E  LP   G P P  P+ A G R R         AAG  G  GAR +        
Sbjct: 281 PGLKGENGLPGENGAPGPMGPRGAPGERGRPGL----PGAAGARGNDGARGSDGQPGPPG 336

Query: 334 AAAAA---AAAAARMDFLSGPSPAASAASPERRDPARQ 368
               A    +  A+ +     SP ++ A  +R +P  Q
Sbjct: 337 PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQ 374


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 47/161 (29%), Positives = 66/161 (40%), Gaps = 23/161 (14%)

Query: 225 AVHPPTPKRARTGPGP---SPLRSGHQVPS-PGSVLSPHMLFGHPPSAAGGGDSGGEGSP 280
           A  PP+P  A+ GP     +PL +    P+ P +V  P      PP A    +      P
Sbjct: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPP 215

Query: 281 EPLLPPAQGPPAPPRPQ------KARGSRSRR----RYLWRWDSAAGVAGG--ARAALSS 328
           +P  PP Q  P PP+PQ        R   + R    R + R+   +G AGG   R  +  
Sbjct: 216 QPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQG 275

Query: 329 SAAEAAAAAAAAAAARMDFLS-------GPSPAASAASPER 362
              E AAA       R+  L+       G +P A++A P R
Sbjct: 276 LLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSR 316



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 37/146 (25%), Positives = 43/146 (29%), Gaps = 35/146 (23%)

Query: 220 VSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGS 279
           +S R A     P+R  T P P                 P    G P +AA          
Sbjct: 91  ISYRNAARVQPPRRGATPPAP-----------------PRAPRGAPAAAAAAAP------ 127

Query: 280 PEPLLPPAQGPPAPPRPQKARGSRSRRRYLWRWDSAAGVAGGARAALSSSAAEAAAAAAA 339
                PP   PP PP P  A       R       AA  A  A  +   +     A  AA
Sbjct: 128 -----PPTPAPPPPPAPVAAAAPARAPR-------AAAAAATAPPSPGPAQPGPRAQRAA 175

Query: 340 AAAARMDFLSGPSPAASAASPERRDP 365
             AA     + P   A  A P R  P
Sbjct: 176 PLAAPPPAPAAPPAVAPPAGPRRAPP 201


>gi|111120318 NK6 transcription factor related, locus 1 [Homo
           sapiens]
          Length = 367

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 50/149 (33%), Positives = 62/149 (41%), Gaps = 21/149 (14%)

Query: 225 AVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLL 284
           A +PP P     GP PS   S     SP   L  H   G  P A GG  S G        
Sbjct: 38  AAYPPLP----AGP-PSSSSSSSSSSSPSPPLGTHNPGGLKPPATGGLSSLGS------- 85

Query: 285 PPAQGPPAPP--------RPQKARGSRSRRRYLWRWDSAAGVAGGARAALSSSAAEAAAA 336
           PP Q   A P        RP     S +         S++  +  A A+ +S+AA AAAA
Sbjct: 86  PPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAA 145

Query: 337 AAAAAAARMDFLSGPSPAASAASPERRDP 365
           AAAAA++    L+G  P  S+ SP    P
Sbjct: 146 AAAAASSPAGLLAG-LPRFSSLSPPPPPP 173


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 50/161 (31%), Positives = 57/161 (35%), Gaps = 30/161 (18%)

Query: 162 QVEEAARGVVRAG---GEGVA--VGEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKE- 215
           Q E  +R   ++G   GEG A   G   +   P+ G G G   G  PG     G  G   
Sbjct: 166 QFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGG 225

Query: 216 -----LVSQVSTRRAVHPPTPKRARTGPGPS---------PLRSGHQVPSPGSVLSPHML 261
                   Q   R  + PP P      P P          P   G + P P  VL P   
Sbjct: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPP--VLFPGQP 283

Query: 262 FGHPPSAAGGGDSG------GEGSPEPLLPPAQGPPAPPRP 296
           FG PP   G    G      G G P    PP QGPP PP P
Sbjct: 284 FGQPP--LGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGP 322


>gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]
          Length = 602

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 31/81 (38%), Positives = 42/81 (51%), Gaps = 3/81 (3%)

Query: 266 PSAAGGGDSGGEGSPEPLLPPA--QGPPAP-PRPQKARGSRSRRRYLWRWDSAAGVAGGA 322
           PS  G   SGG        PPA  Q PP P P PQ+      + +   +     G  GG 
Sbjct: 18  PSEKGAHPSGGADDVAKKPPPAPQQPPPPPAPHPQQHPQQHPQNQAHGKGGHRGGGGGGG 77

Query: 323 RAALSSSAAEAAAAAAAAAAA 343
           +++ SSSA+ AAAAAAA+++A
Sbjct: 78  KSSSSSSASAAAAAAAASSSA 98


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 95/336 (28%), Positives = 130/336 (38%), Gaps = 65/336 (19%)

Query: 7    SSSPIPSPSYLHSGGPGRN----QTWVGG----QGPKAPWPGEGGWDCASPAALACSVGM 58
            ++ P+  P    SG PGR+    QT + G    +GP+      G   C S   L  S GM
Sbjct: 831  ATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFS-GM 889

Query: 59   GRAP---------PG-LGPVGV-GPLVPDLEEGVPGARG--HSHAIVGDPEAAHAVVVAS 105
              AP         PG  GP G+ GP  P    GVPG +G   ++ + G P       + +
Sbjct: 890  PGAPGLWMGSSWQPGPQGPPGIPGPPGPP---GVPGLQGVPGNNGLPGQPG------LTA 940

Query: 106  EDSSVTCTVALHGIPDVAVEVVVASEQQPS-AAREGNRGDATDDVVMGVHEEL-----LI 159
            E  S+   +  H +  +  + V      P     +G +GD     V G+         L 
Sbjct: 941  ELGSLP--IEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLE 998

Query: 160  GPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQ 219
             P+ EEA RG    G  G      L   GP    G+  E+G  PG   + G  G   +  
Sbjct: 999  RPRAEEA-RGDNSEGDPGCVGSPGLP--GPPGLPGQRGEEG-PPGMRGSPGPPGP--IGP 1052

Query: 220  VSTRRAVHPP-----TPKRARTG-------PGPSPLRSGHQVPSPGSVLSPHMLFGHPPS 267
                 AV  P       +R  TG       PGP P + G+    PG+   P  L G    
Sbjct: 1053 PGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGP-PGQPGY----PGAT-GPPGLPGIKGE 1106

Query: 268  AAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGSR 303
                G +G +G P P  P ++G P PP P   RG R
Sbjct: 1107 RGYTGSAGEKGEPGP--PGSEGLPGPPGPAGPRGER 1140



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 26/68 (38%), Positives = 33/68 (48%), Gaps = 8/68 (11%)

Query: 20   GGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGL-GPVGVGPLVPDLE 78
            G PG+    VG  GP  P   +G      P+ L  S G    PPG+ GP G+  L  D +
Sbjct: 1168 GFPGK----VGSPGPPGPQAEKGSEGIRGPSGLPGSPG-PPGPPGIQGPAGLDGL--DGK 1220

Query: 79   EGVPGARG 86
            +G PG RG
Sbjct: 1221 DGKPGLRG 1228



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 27/69 (39%), Positives = 29/69 (42%), Gaps = 4/69 (5%)

Query: 21   GPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVG-VGPLVPDLEE 79
            GP   Q + G  GPK   PG  G      A      GM   P   G +G VGP  P  E 
Sbjct: 1353 GPPGKQGFYGPPGPKGD-PGAAGQK--GQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGER 1409

Query: 80   GVPGARGHS 88
            G PGA G S
Sbjct: 1410 GHPGAPGPS 1418



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 78/327 (23%), Positives = 107/327 (32%), Gaps = 61/327 (18%)

Query: 3   ASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAP 62
           +S  +S  + SP +   G PGR     G  G K    GE G               G A 
Sbjct: 570 SSTGASGDVGSPGFGLPGLPGR----AGVPGLK----GEKG-------------NFGEAG 608

Query: 63  PGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDV 122
           P   P   GP+ P    G+ GA+G       +P      +   +D  V   VAL G    
Sbjct: 609 PAGSPGPPGPVGP---AGIKGAKG-------EPCEPCPALSNLQDGDVR-VVALPGPSGE 657

Query: 123 AVE-----VVVASEQQPSAAR--EGNRGDATDDVVMGVHEEL----LIGPQVEEAARGVV 171
             E       +  +Q  +  R  +G +GDA +    G         L G    +   G  
Sbjct: 658 KGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPK 717

Query: 172 RAGGEGVAVGEELQDT-----------GPRWGEG-EGEEQGREPGSGNTTGTLGKELVSQ 219
              G+G      LQ T           GP+  +G EG  +  +PG     G  G   +  
Sbjct: 718 GEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKG 777

Query: 220 VSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGS 279
           V       P  P R   GP   P   G  +P    +  P    G        G  G +G+
Sbjct: 778 VQGE----PGPPGRGVQGPQGEPGAPG--LPGIQGLPGPRGPPGPTGEKGAQGSPGVKGA 831

Query: 280 PEPLLPPAQGPPAPPRPQKARGSRSRR 306
             P+ PP      PP     +G    R
Sbjct: 832 TGPVGPPGASVSGPPGRDGQQGQTGLR 858



 Score = 28.9 bits (63), Expect = 7.7
 Identities = 76/301 (25%), Positives = 96/301 (31%), Gaps = 47/301 (15%)

Query: 30  GGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVG-PLVPDLEEGVPGARGHS 88
           G QG K    GE    C+S       V    A   +G  G G P +P    GVPG +G  
Sbjct: 544 GIQGIKGE-KGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPG-RAGVPGLKGEK 601

Query: 89  HAI-----VGDP----EAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAARE 139
                    G P        A +  ++        AL  + D  V VV            
Sbjct: 602 GNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEP 661

Query: 140 GNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQ 199
           G  G              L G Q +   RG+    G+    G    D G     G     
Sbjct: 662 GPPGFG------------LPGKQGKAGERGLKGQKGDAGNPG----DPGTPGTTGRPGLS 705

Query: 200 GREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTG-PGPSPLRSGHQVPSPGSVLSP 258
           G EPG     G  G++     +        T    R G PGP   +    V  PG    P
Sbjct: 706 G-EPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQP 764

Query: 259 HM--LFGHP--------PSAAGGGDSGGEGSP-EPLLPPAQG------PPAPPRPQKARG 301
            +  + G P        P   G G  G +G P  P LP  QG      PP P   + A+G
Sbjct: 765 GLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQG 824

Query: 302 S 302
           S
Sbjct: 825 S 825



 Score = 28.9 bits (63), Expect = 7.7
 Identities = 35/116 (30%), Positives = 42/116 (36%), Gaps = 9/116 (7%)

Query: 188  GPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGH 247
            G R   G   E+G EPG   + G  G    +     R     + ++   G    P   G 
Sbjct: 1105 GERGYTGSAGEKG-EPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGP 1163

Query: 248  QVPS--PGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARG 301
              P   PG V SP    G P   A  G  G  G     LP + GPP PP  Q   G
Sbjct: 1164 PGPPGFPGKVGSP----GPPGPQAEKGSEGIRGPSG--LPGSPGPPGPPGIQGPAG 1213


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 86/316 (27%), Positives = 107/316 (33%), Gaps = 65/316 (20%)

Query: 20   GGPGRNQTWVGGQGPKAPW----PGEGG----------WDCASPAALACSVGMG------ 59
            G PG     +GG+GP  P     PG  G               P  L  +   G      
Sbjct: 1347 GEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRG 1406

Query: 60   -RAPPGLGPVGVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHG 118
             R PPG G  G+ P  P L  G+PG+ G    +   P         SED          G
Sbjct: 1407 ERGPPGPGEGGIAPGEPGL-PGLPGSPGPQGPV--GPPGKKGEKGDSED----------G 1453

Query: 119  IPDVAVEVVVASEQQPSA--AREGNRGDATDDVVMG-VHEELLIGPQVEEAARGVVRAGG 175
             P +  +     EQ P       G +GD      +G   E+   GP     +RG+    G
Sbjct: 1454 APGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAG 1513

Query: 176  EGVAVGEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRAR 235
               A G E    GP    G   E+G EPG       +G  +      +  V P  P R  
Sbjct: 1514 RPGAKGPE----GPPGPTGRQGEKG-EPGRPGDPAVVGPAVAGPKGEKGDVGPAGP-RGA 1567

Query: 236  TGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGD------SGGEGSPEPLLPPAQ- 288
            TG        G + P PG VL      G P      GD      +G  G P    PP + 
Sbjct: 1568 TGV------QGERGP-PGLVLP-----GDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEK 1615

Query: 289  ---GPPAPPRPQKARG 301
               G P PP P   RG
Sbjct: 1616 GDPGRPGPPGPVGPRG 1631



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 82/288 (28%), Positives = 96/288 (33%), Gaps = 26/288 (9%)

Query: 29   VGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVGPLVPDLEEGVPGARGHS 88
            VGG G   P PG  G   A PA      G+   P   GP G G   P    G+PG  G S
Sbjct: 2179 VGGHGDPGP-PGAPG--LAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPS 2235

Query: 89   HAI--VGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAAREGNRGDAT 146
              +   G P     V    +  +     A     D     V  S   P     G +G+  
Sbjct: 2236 GLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPV--GPKGEPG 2293

Query: 147  DDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGE-----ELQDTGPRWGEGEGEEQGR 201
                 G     L G + E+ A G    G  G  VGE     +    GPR  +GE    G 
Sbjct: 2294 PTGAPGQAVVGLPGAKGEKGAPG----GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGE 2349

Query: 202  -----EPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVL 256
                 E G     G  G +    V    +  PP P   +   G   L     V       
Sbjct: 2350 PGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQT 2409

Query: 257  SPHMLFGHP-PSAAGG--GDSGGEGSPEPLLPPAQGPPAPPRPQKARG 301
             P    G P PS   G  G  G EG P PL PP  GPP    P  A G
Sbjct: 2410 GPRGEMGQPGPSGERGLAGPPGREGIPGPLGPP--GPPGSVGPPGASG 2455



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 43/157 (27%), Positives = 56/157 (35%), Gaps = 16/157 (10%)

Query: 160  GPQVEEAARGVVRAGGEGVAVGEELQDTGPRW--GEGEGEEQGREPGSGNTTGTLGKELV 217
            GP  +   RG    G  G A+  +  D G R   G GEG     EPG     G+ G +  
Sbjct: 1380 GPLGDPGPRGP--PGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGP 1437

Query: 218  SQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVP-SPGSVLSPHMLFGHPPSAAGGGDSGG 276
                 ++     +   A   PG  P   G Q P  P   + P    G P      G+ G 
Sbjct: 1438 VGPPGKKGEKGDSEDGAPGLPG-QPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGE 1496

Query: 277  EGSPEPL----------LPPAQGPPAPPRPQKARGSR 303
             G P P            P A+GP  PP P   +G +
Sbjct: 1497 RGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEK 1533



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 75/285 (26%), Positives = 98/285 (34%), Gaps = 59/285 (20%)

Query: 29   VGGQGPKAPWPGEGGWDCASPAALACSVGMG-RAPPGLGPVGVGPLVPDLEEGVPGARGH 87
            VG  G K    G+       P        MG R P GL     G   P  + G PG +G 
Sbjct: 2510 VGSAGLKGD-KGDSAVILGPPGPRGAKGDMGERGPRGLD----GDKGPRGDNGDPGDKG- 2563

Query: 88   SHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAAR-EGNRGDAT 146
            S    GD  +A                   G+P   +  ++  + QP AA   G+ G   
Sbjct: 2564 SKGEPGDKGSA-------------------GLP--GLRGLLGPQGQPGAAGIPGDPGSPG 2602

Query: 147  DDVVMGVHEEL----LIGPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQGR- 201
             D V G+  E      +GP+  +  RGV  A G     G++  + GP    G    +G  
Sbjct: 2603 KDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDK-GEAGPPGRPGLAGHKGEM 2661

Query: 202  -EPGSGNTTGTLGKE-LVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPH 259
             EPG    +G  GKE L+     R     P PK  +   G                    
Sbjct: 2662 GEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGER------------------ 2703

Query: 260  MLFGHPPSAAGGGDSGGEGSPEPLLPPAQ-GPPAPPRPQKARGSR 303
               G P      G SG +GS  P  PP   GP  P   Q  +G R
Sbjct: 2704 ---GTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGER 2745



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 66/252 (26%), Positives = 80/252 (31%), Gaps = 44/252 (17%)

Query: 60   RAPPGL-GPVGV-GPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALH 117
            + PPG  GP+G  G      + G PG +G     +G+        +A E           
Sbjct: 1987 QGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKP------- 2039

Query: 118  GIPDVAVEVVVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEG 177
            GIP +        E    A R G RG+  +    G  E+   GP       G     G  
Sbjct: 2040 GIPGLPGRAGGVGE----AGRPGERGERGEKGERG--EQGRDGPPGLPGTPGPPGPPGPK 2093

Query: 178  VAVGEELQDTGPRWGEGEGEEQGR--------EPGSGNTTGTLGKELVSQVSTRRAVHPP 229
            V+V E         G G   EQG         EPGS    G  G   V           P
Sbjct: 2094 VSVDEP--------GPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGV-----------P 2134

Query: 230  TPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQG 289
              K  R  PGP        +P    +  P    G        G  GG G P P  P A G
Sbjct: 2135 GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGP--PGAPG 2192

Query: 290  PPAPPRPQKARG 301
               P  PQ   G
Sbjct: 2193 LAGPAGPQGPSG 2204



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 39/142 (27%), Positives = 50/142 (35%), Gaps = 13/142 (9%)

Query: 172  RAGGEGVAVGEELQDT----GPRWGEGEGEEQGR--EPGS-GNTTGTLGKELVSQVSTRR 224
            RAG  G      L+ +    GPR   GE   +G   EPG+ G   G  G  L  +     
Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPG 1371

Query: 225  AVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLL 284
               PP P+     PGP           PG+ +             G G+ GG    EP L
Sbjct: 1372 PSGPPGPRGPLGDPGPRGPPG-----LPGTAMKGDKGDRGERGPPGPGE-GGIAPGEPGL 1425

Query: 285  PPAQGPPAPPRPQKARGSRSRR 306
            P   G P P  P    G +  +
Sbjct: 1426 PGLPGSPGPQGPVGPPGKKGEK 1447



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 71/310 (22%), Positives = 100/310 (32%), Gaps = 49/310 (15%)

Query: 21   GPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPVGVGPLVPDLEEG 80
            GP      VG +G + P PG+ G         A   G+  AP   GPVG        ++G
Sbjct: 1628 GPRGRDGEVGEKGDEGP-PGDPGLP-----GKAGERGLRGAPGVRGPVGEKG-----DQG 1676

Query: 81   VPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSAA--- 137
             PG  G +    G P ++       E           G P   V+    + ++       
Sbjct: 1677 DPGEDGRN----GSPGSSGPKGDRGEPGPP-------GPPGRLVDTGPGAREKGEPGDRG 1725

Query: 138  REGNRGDATDDVVMGVHEELLI-------GPQVEEAARGVVRAGGEGVAVGEELQD---- 186
            +EG RG   D  + G   E  I       GPQ +   RG     G+    G + +     
Sbjct: 1726 QEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDG 1785

Query: 187  -------TGPRWGEGEGEEQGRE--PGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTG 237
                   +GP    G+  + GR+  PG     G  G      +  +           + G
Sbjct: 1786 KPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNG 1845

Query: 238  PGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGG----GDSGGEGSPEPLLPPAQGPPAP 293
                P   G +     S  S       P    G     G  G  G P P+ PP QG P  
Sbjct: 1846 EPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGV 1905

Query: 294  PRPQKARGSR 303
            P     +G R
Sbjct: 1906 PGGTGPKGDR 1915



 Score = 28.9 bits (63), Expect = 7.7
 Identities = 39/143 (27%), Positives = 52/143 (36%), Gaps = 11/143 (7%)

Query: 160  GPQVEEAARGVVRAGGEGVAVGEELQDTGPRWGEGEGEEQGRE--PGSGNTTGTLGKELV 217
            GP   + A+G   + G+    G+     G +   GE   +G++  PG     G  G E  
Sbjct: 2108 GPPGLKGAKGEPGSNGDQGPKGDR-GVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGK 2166

Query: 218  SQVSTRRAVHPPTPKRARTGPGP--SPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSG 275
              +   R   PP P      PGP  +P  +G   P   S L        PP     G +G
Sbjct: 2167 PGLQGPRG--PPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTG 2224

Query: 276  GEGSPEPLLPPA----QGPPAPP 294
              G P P  P      QG P  P
Sbjct: 2225 AVGLPGPPGPSGLVGPQGSPGLP 2247


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 38/147 (25%), Positives = 51/147 (34%), Gaps = 34/147 (23%)

Query: 210 GTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAA 269
           G+ GK+  S           T   +  GPGP+P                       P+ +
Sbjct: 170 GSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNP----------------------NPTPS 207

Query: 270 GGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGSRSRRRYLWRWDSAAGVAGGARAALSSS 329
            G + GG G P P   P    P  P  +  +G             AA  A  A AA +++
Sbjct: 208 CGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGG------------AAAAAAAAAAAAAAA 255

Query: 330 AAEAAAAAAAAAAARMDFLSGPSPAAS 356
           AA AA   AAA      +  GP P  S
Sbjct: 256 AAAAAGGLAAAGGPGQGWAPGPGPITS 282



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 5/69 (7%)

Query: 9   SPIPSPSYLHSGGPGRNQTWVGGQGPKAPW-----PGEGGWDCASPAALACSVGMGRAPP 63
           +P P+PS   +GG G   +  G  G   P      PG+GG   A+ AA A +     A  
Sbjct: 201 NPNPTPSCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAA 260

Query: 64  GLGPVGVGP 72
           G      GP
Sbjct: 261 GGLAAAGGP 269


>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
          Length = 411

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 38/118 (32%), Positives = 47/118 (39%), Gaps = 4/118 (3%)

Query: 188 GPRWGEGEGEEQGREPG--SGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRS 245
           GP  G   G   G  PG  SG   G +   +   +S    +  P P  A+  PGP  L+ 
Sbjct: 225 GPIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQI-PGPGRLQG 283

Query: 246 GHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGP-PAPPRPQKARGS 302
              + SPG + SP  L G  P    G   G    P P+  P   P PAP  PQ    S
Sbjct: 284 PGPILSPGRMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPLWPQSPDAS 341



 Score = 35.4 bits (80), Expect = 0.082
 Identities = 31/119 (26%), Positives = 44/119 (36%), Gaps = 11/119 (9%)

Query: 187 TGPRWGEGEGEEQGREPG--SGNTTGTLGKELVSQVS--TRRAVHPPTPKRARTGPGPSP 242
           +GP  G   G   G  PG  SG   G +   +   +       +  P P     GP P P
Sbjct: 172 SGPNPGPIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNP-----GPIPGP 226

Query: 243 LRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARG 301
           +      P+PG +  P  + G  P    G   G    P P++ P   P   P P + +G
Sbjct: 227 IPGPISGPNPGPIPGP--ISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQG 283



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 6/66 (9%)

Query: 237 GPGPSPLRSGHQVPSP------GSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGP 290
           GP P+P+    Q+P P      G +  P  +    P+   G  SG    P P   P  GP
Sbjct: 97  GPIPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPISGPVQIPGPFRGPIPGP 156

Query: 291 PAPPRP 296
            + P P
Sbjct: 157 ISGPAP 162



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 19/59 (32%), Positives = 24/59 (40%)

Query: 238 PGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRP 296
           PGP+ + S    P PG +  P  + G       G  SG    P P+  P  GP   P P
Sbjct: 122 PGPAQIPSPIPAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIP 180


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 86/338 (25%), Positives = 110/338 (32%), Gaps = 77/338 (22%)

Query: 21   GPGRNQTWVGGQGPKAPWPGEGGWDC--ASPAALACSVGMGRA-PPG------------- 64
            GP   Q  VG  GPK P PG  G D     P     +   G+  PPG             
Sbjct: 931  GPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 989

Query: 65   LGPVGV----GPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120
             GP+G     GP  P  E+G+PGA G   A  GDP     +      + +       G+P
Sbjct: 990  TGPIGERGHPGPPGPPGEQGLPGAAGKEGA-KGDP-GPQGISGKDGPAGLRGFPGERGLP 1047

Query: 121  DVAVEVVVASEQQPS-----AAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGG 175
                   +   + P          G RG A     +G+      GPQ      G   A G
Sbjct: 1048 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR--PGPQGPPGPAGEKGAPG 1105

Query: 176  EGVAVGEELQD-----------TGPRWGEGEGEEQGR--EPGSGNTTGTLGKELVSQVST 222
            E    G   +D            GP    GE  ++G   EPG   + G  G+        
Sbjct: 1106 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN------- 1158

Query: 223  RRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGH-----------PPSAAG- 270
                 PP P   +   G   +  G   P P        +FG            PP   G 
Sbjct: 1159 ----GPPGPPGLQGPVGAPGIAGGDGEPGP---RGQQGMFGQKGDEGARGFPGPPGPIGL 1211

Query: 271  ------GGDSGGEGSPEPLLPPAQGPPAPPRPQKARGS 302
                   G+ G  G   P+ PP  GPP P  PQ   G+
Sbjct: 1212 QGLPGPPGEKGENGDVGPMGPP--GPPGPRGPQGPNGA 1247



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 80/305 (26%), Positives = 108/305 (35%), Gaps = 51/305 (16%)

Query: 2    RASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRA 61
            R S  ++ PI        G PGR     G QGP  P   +G      P   A   G+   
Sbjct: 1074 RGSAGTAGPI--------GLPGR----PGPQGPPGPAGEKGAPGEKGPQGPAGRDGV--- 1118

Query: 62   PPGLGPVGV-GPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120
                GPVG+ GP  P    G  G +G     +G+P    +     E+        L G  
Sbjct: 1119 ---QGPVGLPGPAGPAGSPGEDGDKGE----IGEPGQKGSKGDKGENGP-PGPPGLQG-- 1168

Query: 121  DVAVEVVVASEQQPS-AAREGNRGDATDDVVMG-------VHEELLIGPQVEEAARGVVR 172
             V    +   + +P    ++G  G   D+   G       +  + L GP  E+   G V 
Sbjct: 1169 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1228

Query: 173  AGGEGVAVGEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPK 232
              G     G      GP+   G    QG  PGS  + G +G+    +     A +P  P 
Sbjct: 1229 PMGPPGPPGPR----GPQGPNGADGPQG-PPGSVGSVGGVGE----KGEPGEAGNPGPPG 1279

Query: 233  RARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPL-LPPAQGPP 291
             A  G GP   R       P     P    G P      GD G +G+P P+  P   GPP
Sbjct: 1280 EAGVG-GPKGERGEKGEAGPPGAAGPPGAKGPP------GDDGPKGNPGPVGFPGDPGPP 1332

Query: 292  APPRP 296
              P P
Sbjct: 1333 GEPGP 1337



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 77/291 (26%), Positives = 105/291 (36%), Gaps = 59/291 (20%)

Query: 26  QTWVGGQGPKAPW-----PGEGGWDCASPAALACSVGMGRAPPGLGPVGV----GPLVPD 76
           Q  +  +GP  P      PG  G   +S A      G    P   GP GV    GP    
Sbjct: 534 QARIALRGPPGPMGLTGRPGPVGGPGSSGAK-----GESGDPGPQGPRGVQGPPGPTGKP 588

Query: 77  LEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSA 136
            + G PGA G    + G+P A                    G+P +  +     E+ P  
Sbjct: 589 GKRGRPGADG-GRGMPGEPGAKG-------------DRGFDGLPGLPGDKGHRGERGP-- 632

Query: 137 AREGNRGDATDDVVMGVHEELLIGPQV---EEAARGVVRAGGEGVAVGEELQD--TGPRW 191
             +G  G   DD + G   E  IGP+    E   RG++   G   A G+       GP  
Sbjct: 633 --QGPPGPPGDDGMRGEDGE--IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 688

Query: 192 GEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPS 251
            +G    QG EPG     G  G + +     +  + PP  K  +  PG + L        
Sbjct: 689 PKGNMGPQG-EPGPPGQQGNPGPQGLP--GPQGPIGPPGEKGPQGKPGLAGL-------- 737

Query: 252 PGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGS 302
           PG+   P    GHP      G+ G  G P P     QGP   P P+  +G+
Sbjct: 738 PGADGPP----GHPGKEGQSGEKGALGPPGP-----QGPIGYPGPRGVKGA 779



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 99/369 (26%), Positives = 114/369 (30%), Gaps = 87/369 (23%)

Query: 20   GGPGRN--QTWVGGQGPKAPW--PGEGG--WDCASPAALACSVGMGR----APPGL-GPV 68
            G  GR+  Q  VG  GP  P   PGE G   +   P         G      PPGL GPV
Sbjct: 1111 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1170

Query: 69   GVGPLVPDLEEGVPGARGHSHAI--VGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEV 126
            G   +     +G PG RG        GD E A               + L G+P    E 
Sbjct: 1171 GAPGIAGG--DGEPGPRGQQGMFGQKGD-EGARGF------PGPPGPIGLQGLPGPPGEK 1221

Query: 127  VVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGE---- 182
                +  P     G  G        G       GPQ    + G V   GE    GE    
Sbjct: 1222 GENGDVGPMGP-PGPPGPRGPQGPNGAD-----GPQGPPGSVGSVGGVGEKGEPGEAGNP 1275

Query: 183  ----ELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGP 238
                E    GP+   GE  E G  PG+    G  G              PP     +  P
Sbjct: 1276 GPPGEAGVGGPKGERGEKGEAG-PPGAAGPPGAKG--------------PPGDDGPKGNP 1320

Query: 239  GPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAG---GGDSGGEGSP-EPLLPPAQGPPAPP 294
            GP        V  PG    P    G P  A     GGD G +G P +P  P   G   PP
Sbjct: 1321 GP--------VGFPGDPGPP----GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1368

Query: 295  RPQKARGSRSRRRYLWRWDSAAGVAG--GARAALSSSAAEAAAAAAAAAAARMDFLSGPS 352
             P   RG             AAG  G  G + A   + AE                 GP 
Sbjct: 1369 GPPGKRGP----------PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV--------GPQ 1410

Query: 353  PAASAASPE 361
              A    PE
Sbjct: 1411 GPAGKPGPE 1419



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 43/156 (27%), Positives = 58/156 (37%), Gaps = 21/156 (13%)

Query: 160  GPQVEEAARGVVRAGGEGVAVGEE--LQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELV 217
            G + E   +G     G G  VG +    +TGP    G     G  PG     G  GKE  
Sbjct: 961  GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG-PPGEQGLPGAAGKE-- 1017

Query: 218  SQVSTRRAVHPPTPKRARTGPGPSPLRS-GHQVPSPGSVLSPHMLFGHPPSAAGG----- 271
                   A   P P+      GP+ LR    +   PG+  +P +  G  P    G     
Sbjct: 1018 ------GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP 1071

Query: 272  GDSGGEGSPEPL----LPPAQGPPAPPRPQKARGSR 303
            G+ G  G+  P+     P  QGPP P   + A G +
Sbjct: 1072 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1107



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 82/304 (26%), Positives = 100/304 (32%), Gaps = 49/304 (16%)

Query: 21   GPGRNQTWVGGQGPKAPWPGEGG-------WDCASPAALACSVGMGRAPPGLGPVGV-GP 72
            GP  +   VGG G K   PGE G            P       G    P   GP G  GP
Sbjct: 1252 GPPGSVGSVGGVGEKGE-PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP 1310

Query: 73   LVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQ 132
               D  +G PG  G      GDP        A +D  V       G P        + E 
Sbjct: 1311 PGDDGPKGNPGPVGFP----GDPGPPGEPGPAGQDG-VGGDKGEDGDPGQPGPPGPSGEA 1365

Query: 133  QPSA--AREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPR 190
             P     + G  G A  +           G Q E+ A+G   AG EG         TGP 
Sbjct: 1366 GPPGPPGKRGPPGAAGAE-----------GRQGEKGAKG--EAGAEGPP-----GKTGPV 1407

Query: 191  WGEGEGEEQGREPGSGNTTGTLGKE----LVSQVSTRRAVHPPTPKRARTGPGPSPLRSG 246
              +G   + G E G     G +G++       Q      + PP     +  PG S    G
Sbjct: 1408 GPQGPAGKPGPE-GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG-SKGEKG 1465

Query: 247  HQ-------VPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKA 299
            H         P          L G   S    GD G  G   PL PP  GPP  P PQ  
Sbjct: 1466 HPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GPPGLPGPQGP 1523

Query: 300  RGSR 303
            +G++
Sbjct: 1524 KGNK 1527


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 86/338 (25%), Positives = 110/338 (32%), Gaps = 77/338 (22%)

Query: 21   GPGRNQTWVGGQGPKAPWPGEGGWDC--ASPAALACSVGMGRA-PPG------------- 64
            GP   Q  VG  GPK P PG  G D     P     +   G+  PPG             
Sbjct: 880  GPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 938

Query: 65   LGPVGV----GPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120
             GP+G     GP  P  E+G+PGA G   A  GDP     +      + +       G+P
Sbjct: 939  TGPIGERGHPGPPGPPGEQGLPGAAGKEGA-KGDP-GPQGISGKDGPAGLRGFPGERGLP 996

Query: 121  DVAVEVVVASEQQPS-----AAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGG 175
                   +   + P          G RG A     +G+      GPQ      G   A G
Sbjct: 997  GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR--PGPQGPPGPAGEKGAPG 1054

Query: 176  EGVAVGEELQD-----------TGPRWGEGEGEEQGR--EPGSGNTTGTLGKELVSQVST 222
            E    G   +D            GP    GE  ++G   EPG   + G  G+        
Sbjct: 1055 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN------- 1107

Query: 223  RRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGH-----------PPSAAG- 270
                 PP P   +   G   +  G   P P        +FG            PP   G 
Sbjct: 1108 ----GPPGPPGLQGPVGAPGIAGGDGEPGP---RGQQGMFGQKGDEGARGFPGPPGPIGL 1160

Query: 271  ------GGDSGGEGSPEPLLPPAQGPPAPPRPQKARGS 302
                   G+ G  G   P+ PP  GPP P  PQ   G+
Sbjct: 1161 QGLPGPPGEKGENGDVGPMGPP--GPPGPRGPQGPNGA 1196



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 80/305 (26%), Positives = 108/305 (35%), Gaps = 51/305 (16%)

Query: 2    RASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRA 61
            R S  ++ PI        G PGR     G QGP  P   +G      P   A   G+   
Sbjct: 1023 RGSAGTAGPI--------GLPGR----PGPQGPPGPAGEKGAPGEKGPQGPAGRDGV--- 1067

Query: 62   PPGLGPVGV-GPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120
                GPVG+ GP  P    G  G +G     +G+P    +     E+        L G  
Sbjct: 1068 ---QGPVGLPGPAGPAGSPGEDGDKGE----IGEPGQKGSKGDKGENGP-PGPPGLQG-- 1117

Query: 121  DVAVEVVVASEQQPS-AAREGNRGDATDDVVMG-------VHEELLIGPQVEEAARGVVR 172
             V    +   + +P    ++G  G   D+   G       +  + L GP  E+   G V 
Sbjct: 1118 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1177

Query: 173  AGGEGVAVGEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPK 232
              G     G      GP+   G    QG  PGS  + G +G+    +     A +P  P 
Sbjct: 1178 PMGPPGPPGPR----GPQGPNGADGPQG-PPGSVGSVGGVGE----KGEPGEAGNPGPPG 1228

Query: 233  RARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPL-LPPAQGPP 291
             A  G GP   R       P     P    G P      GD G +G+P P+  P   GPP
Sbjct: 1229 EAGVG-GPKGERGEKGEAGPPGAAGPPGAKGPP------GDDGPKGNPGPVGFPGDPGPP 1281

Query: 292  APPRP 296
              P P
Sbjct: 1282 GEPGP 1286



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 77/291 (26%), Positives = 105/291 (36%), Gaps = 59/291 (20%)

Query: 26  QTWVGGQGPKAPW-----PGEGGWDCASPAALACSVGMGRAPPGLGPVGV----GPLVPD 76
           Q  +  +GP  P      PG  G   +S A      G    P   GP GV    GP    
Sbjct: 483 QARIALRGPPGPMGLTGRPGPVGGPGSSGAK-----GESGDPGPQGPRGVQGPPGPTGKP 537

Query: 77  LEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSA 136
            + G PGA G    + G+P A                    G+P +  +     E+ P  
Sbjct: 538 GKRGRPGADG-GRGMPGEPGAKG-------------DRGFDGLPGLPGDKGHRGERGP-- 581

Query: 137 AREGNRGDATDDVVMGVHEELLIGPQV---EEAARGVVRAGGEGVAVGEELQD--TGPRW 191
             +G  G   DD + G   E  IGP+    E   RG++   G   A G+       GP  
Sbjct: 582 --QGPPGPPGDDGMRGEDGE--IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 637

Query: 192 GEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPS 251
            +G    QG EPG     G  G + +     +  + PP  K  +  PG + L        
Sbjct: 638 PKGNMGPQG-EPGPPGQQGNPGPQGLP--GPQGPIGPPGEKGPQGKPGLAGL-------- 686

Query: 252 PGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGS 302
           PG+   P    GHP      G+ G  G P P     QGP   P P+  +G+
Sbjct: 687 PGADGPP----GHPGKEGQSGEKGALGPPGP-----QGPIGYPGPRGVKGA 728



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 99/369 (26%), Positives = 114/369 (30%), Gaps = 87/369 (23%)

Query: 20   GGPGRN--QTWVGGQGPKAPW--PGEGG--WDCASPAALACSVGMGR----APPGL-GPV 68
            G  GR+  Q  VG  GP  P   PGE G   +   P         G      PPGL GPV
Sbjct: 1060 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1119

Query: 69   GVGPLVPDLEEGVPGARGHSHAI--VGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEV 126
            G   +     +G PG RG        GD E A               + L G+P    E 
Sbjct: 1120 GAPGIAGG--DGEPGPRGQQGMFGQKGD-EGARGF------PGPPGPIGLQGLPGPPGEK 1170

Query: 127  VVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGE---- 182
                +  P     G  G        G       GPQ    + G V   GE    GE    
Sbjct: 1171 GENGDVGPMGP-PGPPGPRGPQGPNGAD-----GPQGPPGSVGSVGGVGEKGEPGEAGNP 1224

Query: 183  ----ELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGP 238
                E    GP+   GE  E G  PG+    G  G              PP     +  P
Sbjct: 1225 GPPGEAGVGGPKGERGEKGEAG-PPGAAGPPGAKG--------------PPGDDGPKGNP 1269

Query: 239  GPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAG---GGDSGGEGSP-EPLLPPAQGPPAPP 294
            GP        V  PG    P    G P  A     GGD G +G P +P  P   G   PP
Sbjct: 1270 GP--------VGFPGDPGPP----GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1317

Query: 295  RPQKARGSRSRRRYLWRWDSAAGVAG--GARAALSSSAAEAAAAAAAAAAARMDFLSGPS 352
             P   RG             AAG  G  G + A   + AE                 GP 
Sbjct: 1318 GPPGKRGP----------PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV--------GPQ 1359

Query: 353  PAASAASPE 361
              A    PE
Sbjct: 1360 GPAGKPGPE 1368



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 43/156 (27%), Positives = 58/156 (37%), Gaps = 21/156 (13%)

Query: 160  GPQVEEAARGVVRAGGEGVAVGEE--LQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELV 217
            G + E   +G     G G  VG +    +TGP    G     G  PG     G  GKE  
Sbjct: 910  GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG-PPGEQGLPGAAGKE-- 966

Query: 218  SQVSTRRAVHPPTPKRARTGPGPSPLRS-GHQVPSPGSVLSPHMLFGHPPSAAGG----- 271
                   A   P P+      GP+ LR    +   PG+  +P +  G  P    G     
Sbjct: 967  ------GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP 1020

Query: 272  GDSGGEGSPEPL----LPPAQGPPAPPRPQKARGSR 303
            G+ G  G+  P+     P  QGPP P   + A G +
Sbjct: 1021 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1056



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 82/304 (26%), Positives = 100/304 (32%), Gaps = 49/304 (16%)

Query: 21   GPGRNQTWVGGQGPKAPWPGEGG-------WDCASPAALACSVGMGRAPPGLGPVGV-GP 72
            GP  +   VGG G K   PGE G            P       G    P   GP G  GP
Sbjct: 1201 GPPGSVGSVGGVGEKGE-PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP 1259

Query: 73   LVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQ 132
               D  +G PG  G      GDP        A +D  V       G P        + E 
Sbjct: 1260 PGDDGPKGNPGPVGFP----GDPGPPGEPGPAGQDG-VGGDKGEDGDPGQPGPPGPSGEA 1314

Query: 133  QPSA--AREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPR 190
             P     + G  G A  +           G Q E+ A+G   AG EG         TGP 
Sbjct: 1315 GPPGPPGKRGPPGAAGAE-----------GRQGEKGAKG--EAGAEGPP-----GKTGPV 1356

Query: 191  WGEGEGEEQGREPGSGNTTGTLGKE----LVSQVSTRRAVHPPTPKRARTGPGPSPLRSG 246
              +G   + G E G     G +G++       Q      + PP     +  PG S    G
Sbjct: 1357 GPQGPAGKPGPE-GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG-SKGEKG 1414

Query: 247  HQ-------VPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKA 299
            H         P          L G   S    GD G  G   PL PP  GPP  P PQ  
Sbjct: 1415 HPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GPPGLPGPQGP 1472

Query: 300  RGSR 303
            +G++
Sbjct: 1473 KGNK 1476


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 86/338 (25%), Positives = 110/338 (32%), Gaps = 77/338 (22%)

Query: 21   GPGRNQTWVGGQGPKAPWPGEGGWDC--ASPAALACSVGMGRA-PPG------------- 64
            GP   Q  VG  GPK P PG  G D     P     +   G+  PPG             
Sbjct: 919  GPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 977

Query: 65   LGPVGV----GPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120
             GP+G     GP  P  E+G+PGA G   A  GDP     +      + +       G+P
Sbjct: 978  TGPIGERGHPGPPGPPGEQGLPGAAGKEGA-KGDP-GPQGISGKDGPAGLRGFPGERGLP 1035

Query: 121  DVAVEVVVASEQQPS-----AAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGG 175
                   +   + P          G RG A     +G+      GPQ      G   A G
Sbjct: 1036 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR--PGPQGPPGPAGEKGAPG 1093

Query: 176  EGVAVGEELQD-----------TGPRWGEGEGEEQGR--EPGSGNTTGTLGKELVSQVST 222
            E    G   +D            GP    GE  ++G   EPG   + G  G+        
Sbjct: 1094 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN------- 1146

Query: 223  RRAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGH-----------PPSAAG- 270
                 PP P   +   G   +  G   P P        +FG            PP   G 
Sbjct: 1147 ----GPPGPPGLQGPVGAPGIAGGDGEPGP---RGQQGMFGQKGDEGARGFPGPPGPIGL 1199

Query: 271  ------GGDSGGEGSPEPLLPPAQGPPAPPRPQKARGS 302
                   G+ G  G   P+ PP  GPP P  PQ   G+
Sbjct: 1200 QGLPGPPGEKGENGDVGPMGPP--GPPGPRGPQGPNGA 1235



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 80/305 (26%), Positives = 108/305 (35%), Gaps = 51/305 (16%)

Query: 2    RASCSSSSPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRA 61
            R S  ++ PI        G PGR     G QGP  P   +G      P   A   G+   
Sbjct: 1062 RGSAGTAGPI--------GLPGR----PGPQGPPGPAGEKGAPGEKGPQGPAGRDGV--- 1106

Query: 62   PPGLGPVGV-GPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIP 120
                GPVG+ GP  P    G  G +G     +G+P    +     E+        L G  
Sbjct: 1107 ---QGPVGLPGPAGPAGSPGEDGDKGE----IGEPGQKGSKGDKGENGP-PGPPGLQG-- 1156

Query: 121  DVAVEVVVASEQQPS-AAREGNRGDATDDVVMG-------VHEELLIGPQVEEAARGVVR 172
             V    +   + +P    ++G  G   D+   G       +  + L GP  E+   G V 
Sbjct: 1157 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1216

Query: 173  AGGEGVAVGEELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPK 232
              G     G      GP+   G    QG  PGS  + G +G+    +     A +P  P 
Sbjct: 1217 PMGPPGPPGPR----GPQGPNGADGPQG-PPGSVGSVGGVGE----KGEPGEAGNPGPPG 1267

Query: 233  RARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPL-LPPAQGPP 291
             A  G GP   R       P     P    G P      GD G +G+P P+  P   GPP
Sbjct: 1268 EAGVG-GPKGERGEKGEAGPPGAAGPPGAKGPP------GDDGPKGNPGPVGFPGDPGPP 1320

Query: 292  APPRP 296
              P P
Sbjct: 1321 GEPGP 1325



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 77/291 (26%), Positives = 105/291 (36%), Gaps = 59/291 (20%)

Query: 26  QTWVGGQGPKAPW-----PGEGGWDCASPAALACSVGMGRAPPGLGPVGV----GPLVPD 76
           Q  +  +GP  P      PG  G   +S A      G    P   GP GV    GP    
Sbjct: 522 QARIALRGPPGPMGLTGRPGPVGGPGSSGAK-----GESGDPGPQGPRGVQGPPGPTGKP 576

Query: 77  LEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQQPSA 136
            + G PGA G    + G+P A                    G+P +  +     E+ P  
Sbjct: 577 GKRGRPGADG-GRGMPGEPGAKG-------------DRGFDGLPGLPGDKGHRGERGP-- 620

Query: 137 AREGNRGDATDDVVMGVHEELLIGPQV---EEAARGVVRAGGEGVAVGEELQD--TGPRW 191
             +G  G   DD + G   E  IGP+    E   RG++   G   A G+       GP  
Sbjct: 621 --QGPPGPPGDDGMRGEDGE--IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 676

Query: 192 GEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGPGPSPLRSGHQVPS 251
            +G    QG EPG     G  G + +     +  + PP  K  +  PG + L        
Sbjct: 677 PKGNMGPQG-EPGPPGQQGNPGPQGLP--GPQGPIGPPGEKGPQGKPGLAGL-------- 725

Query: 252 PGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKARGS 302
           PG+   P    GHP      G+ G  G P P     QGP   P P+  +G+
Sbjct: 726 PGADGPP----GHPGKEGQSGEKGALGPPGP-----QGPIGYPGPRGVKGA 767



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 99/369 (26%), Positives = 114/369 (30%), Gaps = 87/369 (23%)

Query: 20   GGPGRN--QTWVGGQGPKAPW--PGEGG--WDCASPAALACSVGMGR----APPGL-GPV 68
            G  GR+  Q  VG  GP  P   PGE G   +   P         G      PPGL GPV
Sbjct: 1099 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1158

Query: 69   GVGPLVPDLEEGVPGARGHSHAI--VGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEV 126
            G   +     +G PG RG        GD E A               + L G+P    E 
Sbjct: 1159 GAPGIAGG--DGEPGPRGQQGMFGQKGD-EGARGF------PGPPGPIGLQGLPGPPGEK 1209

Query: 127  VVASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGE---- 182
                +  P     G  G        G       GPQ    + G V   GE    GE    
Sbjct: 1210 GENGDVGPMGP-PGPPGPRGPQGPNGAD-----GPQGPPGSVGSVGGVGEKGEPGEAGNP 1263

Query: 183  ----ELQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPTPKRARTGP 238
                E    GP+   GE  E G  PG+    G  G              PP     +  P
Sbjct: 1264 GPPGEAGVGGPKGERGEKGEAG-PPGAAGPPGAKG--------------PPGDDGPKGNP 1308

Query: 239  GPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAG---GGDSGGEGSP-EPLLPPAQGPPAPP 294
            GP        V  PG    P    G P  A     GGD G +G P +P  P   G   PP
Sbjct: 1309 GP--------VGFPGDPGPP----GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1356

Query: 295  RPQKARGSRSRRRYLWRWDSAAGVAG--GARAALSSSAAEAAAAAAAAAAARMDFLSGPS 352
             P   RG             AAG  G  G + A   + AE                 GP 
Sbjct: 1357 GPPGKRGP----------PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV--------GPQ 1398

Query: 353  PAASAASPE 361
              A    PE
Sbjct: 1399 GPAGKPGPE 1407



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 43/156 (27%), Positives = 58/156 (37%), Gaps = 21/156 (13%)

Query: 160  GPQVEEAARGVVRAGGEGVAVGEE--LQDTGPRWGEGEGEEQGREPGSGNTTGTLGKELV 217
            G + E   +G     G G  VG +    +TGP    G     G  PG     G  GKE  
Sbjct: 949  GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG-PPGEQGLPGAAGKE-- 1005

Query: 218  SQVSTRRAVHPPTPKRARTGPGPSPLRS-GHQVPSPGSVLSPHMLFGHPPSAAGG----- 271
                   A   P P+      GP+ LR    +   PG+  +P +  G  P    G     
Sbjct: 1006 ------GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP 1059

Query: 272  GDSGGEGSPEPL----LPPAQGPPAPPRPQKARGSR 303
            G+ G  G+  P+     P  QGPP P   + A G +
Sbjct: 1060 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1095



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 82/304 (26%), Positives = 100/304 (32%), Gaps = 49/304 (16%)

Query: 21   GPGRNQTWVGGQGPKAPWPGEGG-------WDCASPAALACSVGMGRAPPGLGPVGV-GP 72
            GP  +   VGG G K   PGE G            P       G    P   GP G  GP
Sbjct: 1240 GPPGSVGSVGGVGEKGE-PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP 1298

Query: 73   LVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGIPDVAVEVVVASEQ 132
               D  +G PG  G      GDP        A +D  V       G P        + E 
Sbjct: 1299 PGDDGPKGNPGPVGFP----GDPGPPGEPGPAGQDG-VGGDKGEDGDPGQPGPPGPSGEA 1353

Query: 133  QPSA--AREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAGGEGVAVGEELQDTGPR 190
             P     + G  G A  +           G Q E+ A+G   AG EG         TGP 
Sbjct: 1354 GPPGPPGKRGPPGAAGAE-----------GRQGEKGAKG--EAGAEGPP-----GKTGPV 1395

Query: 191  WGEGEGEEQGREPGSGNTTGTLGKE----LVSQVSTRRAVHPPTPKRARTGPGPSPLRSG 246
              +G   + G E G     G +G++       Q      + PP     +  PG S    G
Sbjct: 1396 GPQGPAGKPGPE-GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG-SKGEKG 1453

Query: 247  HQ-------VPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPLLPPAQGPPAPPRPQKA 299
            H         P          L G   S    GD G  G   PL PP  GPP  P PQ  
Sbjct: 1454 HPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GPPGLPGPQGP 1511

Query: 300  RGSR 303
            +G++
Sbjct: 1512 KGNK 1515


>gi|38150007 small nuclear ribonucleoprotein polypeptide B/B'
           isoform B' [Homo sapiens]
          Length = 240

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 36/130 (27%), Positives = 49/130 (37%), Gaps = 14/130 (10%)

Query: 169 GVVRAGGEGVAVGEELQDT-----GPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTR 223
           G+ RA G G+  G  +        GP  G G   +Q   P    T         + ++  
Sbjct: 105 GIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGA 164

Query: 224 RAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPL 283
              +PP     R GP P P+  G   P PG +  P  +   PP     G   G G+P  +
Sbjct: 165 PTQYPP----GRGGP-PPPM--GRGAPPPGMMGPPPGM--RPPMGPPMGIPPGRGTPMGM 215

Query: 284 LPPAQGPPAP 293
            PP   PP P
Sbjct: 216 PPPGMRPPPP 225


>gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isoform
           B [Homo sapiens]
          Length = 231

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 36/130 (27%), Positives = 49/130 (37%), Gaps = 14/130 (10%)

Query: 169 GVVRAGGEGVAVGEELQDT-----GPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTR 223
           G+ RA G G+  G  +        GP  G G   +Q   P    T         + ++  
Sbjct: 105 GIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGA 164

Query: 224 RAVHPPTPKRARTGPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSAAGGGDSGGEGSPEPL 283
              +PP     R GP P P+  G   P PG +  P  +   PP     G   G G+P  +
Sbjct: 165 PTQYPP----GRGGP-PPPM--GRGAPPPGMMGPPPGM--RPPMGPPMGIPPGRGTPMGM 215

Query: 284 LPPAQGPPAP 293
            PP   PP P
Sbjct: 216 PPPGMRPPPP 225


>gi|22027609 alpha 1 type XIII collagen isoform 19 [Homo sapiens]
          Length = 610

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 93/356 (26%), Positives = 122/356 (34%), Gaps = 82/356 (23%)

Query: 5   CSSSSP--IPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAP 62
           C SS P  + S   +   G     +  G  GP  P PG  G            +G    P
Sbjct: 192 CLSSMPAALRSSQIIALKGEQSQASIQGPPGPPGP-PGPSG-----------PLGHPGLP 239

Query: 63  PGLGPVGV-GPLVPDLEEGVPGARGHS--HAIVGDP-----EAAHAVVVASEDSSVTCTV 114
             +GP G+ GP  P  + G+ G  G      + G P     + A  + VA          
Sbjct: 240 GPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEP---- 295

Query: 115 ALHGIPDVAVEVVVASEQQPSA----AREGNRGDATDDVVMGVHEELLIGPQVEEAARGV 170
              GIP    E    +E  P       ++G +GDA + +  G  E    GP       G 
Sbjct: 296 ---GIPGTKGEK--GAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEP---GPPGLPGPPGP 347

Query: 171 VRAGGEGVAVGEELQ--DTGPRWGEGEGEEQGR-----EPGSGNTTGTLGK--ELVSQVS 221
               G    VG   Q  D G R   GE    G      EPG G      G   E + ++ 
Sbjct: 348 KGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIR 407

Query: 222 TRRAVHPP--------------TPKRARTG-PGPSPLRSGHQVP--SPGSVLSPHMLF-- 262
           T   + PP                ++   G PGP P   G + P   PG +  P      
Sbjct: 408 TLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGP-PGHDGEKGPRGKPGDMGPPGPQGPP 466

Query: 263 ------------GHP--PSAAGG-GDSGGEGSPEPLLPPAQGPPAPPRPQKARGSR 303
                       GHP  P   G  G++G  GSP P LP  +GPP PP  Q   G +
Sbjct: 467 GKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGPPGPPGLQGVPGPK 522


>gi|22027601 alpha 1 type XIII collagen isoform 15 [Homo sapiens]
          Length = 668

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 93/356 (26%), Positives = 122/356 (34%), Gaps = 82/356 (23%)

Query: 5   CSSSSP--IPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAP 62
           C SS P  + S   +   G     +  G  GP  P PG  G            +G    P
Sbjct: 221 CLSSMPAALRSSQIIALKGEQSQASIQGPPGPPGP-PGPSG-----------PLGHPGLP 268

Query: 63  PGLGPVGV-GPLVPDLEEGVPGARGHS--HAIVGDP-----EAAHAVVVASEDSSVTCTV 114
             +GP G+ GP  P  + G+ G  G      + G P     + A  + VA          
Sbjct: 269 GPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEP---- 324

Query: 115 ALHGIPDVAVEVVVASEQQPSA----AREGNRGDATDDVVMGVHEELLIGPQVEEAARGV 170
              GIP    E    +E  P       ++G +GDA + +  G  E    GP       G 
Sbjct: 325 ---GIPGTKGEK--GAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEP---GPPGLPGPPGP 376

Query: 171 VRAGGEGVAVGEELQ--DTGPRWGEGEGEEQGR-----EPGSGNTTGTLGK--ELVSQVS 221
               G    VG   Q  D G R   GE    G      EPG G      G   E + ++ 
Sbjct: 377 KGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIR 436

Query: 222 TRRAVHPP--------------TPKRARTG-PGPSPLRSGHQVP--SPGSVLSPHMLF-- 262
           T   + PP                ++   G PGP P   G + P   PG +  P      
Sbjct: 437 TLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGP-PGHDGEKGPRGKPGDMGPPGPQGPP 495

Query: 263 ------------GHP--PSAAGG-GDSGGEGSPEPLLPPAQGPPAPPRPQKARGSR 303
                       GHP  P   G  G++G  GSP P LP  +GPP PP  Q   G +
Sbjct: 496 GKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGPPGPPGLQGVPGPK 551


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 81/378 (21%), Positives = 132/378 (34%), Gaps = 40/378 (10%)

Query: 9   SPIPSPSYLHSGGPGRNQTWVGGQGPKAPWPGEGGWDCASPAALACSVGMGRAPPGLGPV 68
           SP  SP+    G P + ++    +GP  P PG    + A   ++        APP +G V
Sbjct: 248 SPAHSPAKQPLGKPDQERS----RGPGGPQPGSRQAETARATSVP-GPAQAAAPPEVGRV 302

Query: 69  GVGPLVPDLEEGVPGARGHSHAIVGDPEAAHAVVVASEDSSVTCTVALHGI-PDVAVEVV 127
              P  P              A      A  A + A+E +    T  L G+   +  +  
Sbjct: 303 SPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQAS 362

Query: 128 VASEQQPSAAREGNRGDATDDVVMGVHEELLIGPQVEEAARGVVRAG-GEGVAVGEELQD 186
                QP A  +G    +          +++     +EA    + +G G G A G + + 
Sbjct: 363 TLMSVQPEADTQGQPAPSKGT------PKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEP 416

Query: 187 TGPRWGEGEGEEQGREPGSGNTTGTLGKELVSQVSTRRAVHPPT-PKRARTGP-GPSPLR 244
            G R G G G   G  P +G TT         Q +++ A  P T PK     P   + L 
Sbjct: 417 -GARMGPGSGP--GALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELN 473

Query: 245 SGHQVPSPGSVLSPHML-------FGHPPSAAGGGD------------SGGEGSPEPLLP 285
            G + P+  +  +   L       F   P      +             G  G P PL P
Sbjct: 474 VGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPP 533

Query: 286 PAQGPPAPPRPQKARGSRSRRRYLWRWDSAAGVAGGARAALSSSAAEAAAAAAAAAAARM 345
           P    P    P +A G+   ++   +     G   G   A +S  +  A+   + A+ + 
Sbjct: 534 PTSQQPPVGAPHRASGTSPLKQ---KGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQA 590

Query: 346 DFLSGPSPAASAASPERR 363
             L    P+ + +S + +
Sbjct: 591 KPLRASEPSKTPSSVQEK 608



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 43/128 (33%), Positives = 50/128 (39%), Gaps = 12/128 (9%)

Query: 237 GPGPSPLRSGHQVPSPGSVLSPHMLFGHPPSA-AGGGDSGGEGSPEPL-LPPAQGPPAPP 294
           G G  PL  G   P PG    P    G PPSA AGGG     G+     +PP  GP   P
Sbjct: 10  GAGDGPLPPGGAGPGPGPGPGPGA--GKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGP 67

Query: 295 RPQKARGSRSRRRYLWRWDSAAGVAGGARAALSSSAAEAAAAAAAAAAARMDFLSGPSPA 354
            P    GS SRR             G  RAA S +  +A+A      + R     GP+  
Sbjct: 68  GPGPGPGSTSRRL------DPKEPLGNQRAA-SPTPKQASATTPGHESPRETRAQGPA-G 119

Query: 355 ASAASPER 362
             A  P R
Sbjct: 120 QEADGPRR 127



 Score = 28.9 bits (63), Expect = 7.7
 Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 20/92 (21%)

Query: 228  PPTPKRARTGPGPSPLRSGHQVPSP--GSVLSPHML-----FGHPPSAAGGGD------- 273
            P TP      P P+ L  G+  P+   GS  SP        +GH P+ A  G        
Sbjct: 1378 PGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQ 1437

Query: 274  ------SGGEGSPEPLLPPAQGPPAPPRPQKA 299
                  + G  + E  L  + G    P+P +A
Sbjct: 1438 APSGLAAAGRAAREKPLSASDGEGGTPQPSRA 1469


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.130    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,645,532
Number of Sequences: 37866
Number of extensions: 1437509
Number of successful extensions: 16026
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 243
Number of HSP's successfully gapped in prelim test: 1138
Number of HSP's that attempted gapping in prelim test: 10161
Number of HSP's gapped (non-prelim): 5090
length of query: 368
length of database: 18,247,518
effective HSP length: 104
effective length of query: 264
effective length of database: 14,309,454
effective search space: 3777695856
effective search space used: 3777695856
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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