Guide to the Human Genome
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Search of human proteins with 239750914

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239750914 PREDICTED: hypothetical protein XP_002347614 [Homo
sapiens]
         (492 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239750914 PREDICTED: hypothetical protein XP_002347614 [Homo ...  1009   0.0  
gi|239745312 PREDICTED: hypothetical protein XP_002343435 [Homo ...  1009   0.0  
gi|239756393 PREDICTED: hypothetical protein XP_002344913 [Homo ...   664   0.0  
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      54   3e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    53   7e-07
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      52   1e-06
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    52   1e-06
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    52   1e-06
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    52   1e-06
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          51   3e-06
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ...    51   3e-06
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [...    51   3e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    50   4e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    50   4e-06
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              50   5e-06
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    50   6e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    49   1e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    49   1e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    49   1e-05
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         48   2e-05
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    47   4e-05
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    46   7e-05
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    46   7e-05
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    46   7e-05
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    46   7e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    46   7e-05
gi|239757942 PREDICTED: hypothetical protein XP_002346387 [Homo ...    46   7e-05
gi|40353727 synaptopodin isoform A [Homo sapiens]                      46   7e-05
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             46   7e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        46   7e-05

>gi|239750914 PREDICTED: hypothetical protein XP_002347614 [Homo
           sapiens]
          Length = 492

 Score = 1009 bits (2609), Expect = 0.0
 Identities = 492/492 (100%), Positives = 492/492 (100%)

Query: 1   MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60
           MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF
Sbjct: 1   MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60

Query: 61  GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120
           GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA
Sbjct: 61  GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120

Query: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180
           GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR
Sbjct: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180

Query: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240
           PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS
Sbjct: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240

Query: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300
           VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR
Sbjct: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300

Query: 301 SLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGE 360
           SLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGE
Sbjct: 301 SLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGE 360

Query: 361 GGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPG 420
           GGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPG
Sbjct: 361 GGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPG 420

Query: 421 GRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDLSVGVSAASSSLGS 480
           GRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDLSVGVSAASSSLGS
Sbjct: 421 GRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDLSVGVSAASSSLGS 480

Query: 481 TELEKNMGSGGG 492
           TELEKNMGSGGG
Sbjct: 481 TELEKNMGSGGG 492


>gi|239745312 PREDICTED: hypothetical protein XP_002343435 [Homo
           sapiens]
          Length = 492

 Score = 1009 bits (2609), Expect = 0.0
 Identities = 492/492 (100%), Positives = 492/492 (100%)

Query: 1   MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60
           MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF
Sbjct: 1   MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60

Query: 61  GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120
           GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA
Sbjct: 61  GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120

Query: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180
           GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR
Sbjct: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180

Query: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240
           PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS
Sbjct: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240

Query: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300
           VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR
Sbjct: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300

Query: 301 SLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGE 360
           SLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGE
Sbjct: 301 SLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGE 360

Query: 361 GGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPG 420
           GGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPG
Sbjct: 361 GGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPG 420

Query: 421 GRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDLSVGVSAASSSLGS 480
           GRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDLSVGVSAASSSLGS
Sbjct: 421 GRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDLSVGVSAASSSLGS 480

Query: 481 TELEKNMGSGGG 492
           TELEKNMGSGGG
Sbjct: 481 TELEKNMGSGGG 492


>gi|239756393 PREDICTED: hypothetical protein XP_002344913 [Homo
           sapiens]
          Length = 422

 Score =  664 bits (1712), Expect = 0.0
 Identities = 349/431 (80%), Positives = 359/431 (83%), Gaps = 20/431 (4%)

Query: 1   MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60
           MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF
Sbjct: 1   MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60

Query: 61  GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120
           GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA
Sbjct: 61  GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120

Query: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180
           GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR
Sbjct: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180

Query: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240
           PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS
Sbjct: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240

Query: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300
           VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR
Sbjct: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300

Query: 301 SLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRG- 359
           SLVAPSESGSAG+R GTNG ATPR+        G K +       H   P   F      
Sbjct: 301 SLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGGKAKA------HGWAPLTAFLRRLHS 354

Query: 360 -----EGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPL----PCLPPAAVC 410
                +GG GG  A +T+ RA P R      R++   A  G   PPL     CLP  +  
Sbjct: 355 ALVGVKGGAGG--AALTSLRAVPAREGGAGSRSEPREAARG-QEPPLRHCRACLPQLSAM 411

Query: 411 HALAGAGAPGG 421
            +  G G P G
Sbjct: 412 RS-PGQGRPEG 421


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 62/178 (34%), Positives = 65/178 (36%), Gaps = 42/178 (23%)

Query: 299 PRSLVAPSESGSAGRRG--------GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPP 350
           P  L AP  SG+ G RG        G  G A PR   G     G KG     GAP S   
Sbjct: 664 PGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGA 723

Query: 351 P-----PPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLP 405
           P     P  R   G  G  G R D  AG          P  A  S  + G      P  P
Sbjct: 724 PGLQGMPGERGAAGLPGPKGDRGD--AG----------PKGADGSPGKDGVRGLTGPIGP 771

Query: 406 PAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
           P         AGAPG + E G S         G A PT A  AP  R  PGP PGP G
Sbjct: 772 PGP-------AGAPGDKGESGPS---------GPAGPTGARGAPGDRGEPGP-PGPAG 812



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 61/207 (29%), Positives = 73/207 (35%), Gaps = 32/207 (15%)

Query: 270 LSSPFFPKQLGSLSLELP-ARLPTRCLPSPPRSLVAPSESGSAGRRG--GTNGVATPREK 326
           LS  +  K  G +S+  P      R LP PP +       G  G  G  G +G   PR  
Sbjct: 163 LSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGP 222

Query: 327 LGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRG----------EGGGGGSRADVTAGRAR 376
            G     G  G+  + G P    PP P +  RG          +G  G S  D   G A 
Sbjct: 223 PGPPGKNGDDGEAGKPGRPGERGPPGP-QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAG 281

Query: 377 PRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIRG 436
           P   + EP     +GA PG   P                 G PG R   G +PG    RG
Sbjct: 282 PAGPKGEPGSPGENGA-PGQMGP----------------RGLPGERGRPG-APGPAGARG 323

Query: 437 GGAAVPTAAPPAPLPRWGPGPLPGPTG 463
              A   A PP P    GP   PG  G
Sbjct: 324 NDGATGAAGPPGPTGPAGPPGFPGAVG 350



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 106/374 (28%), Positives = 121/374 (32%), Gaps = 78/374 (20%)

Query: 140  GAEGKGGGPQALGR-GRR----VNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE 194
            GA G  G P   G  G R    + GP+G DR   G + A     +   R L      PG 
Sbjct: 716  GAPGSQGAPGLQGMPGERGAAGLPGPKG-DRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774

Query: 195  GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAG-- 252
               A     E+GPS    P+          R      G PG        P      AG  
Sbjct: 775  AG-APGDKGESGPSGPAGPTGA--------RGAPGDRGEPG--------PPGPAGFAGPP 817

Query: 253  GKDKTPPFSQEVDDPHALSSPFFPKQLGSL-------SLELPARLPTRCLPSPPRSLVAP 305
            G D  P    E  D  A      P   G         ++  P     R    PP +   P
Sbjct: 818  GADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFP 877

Query: 306  SESGSAGRRG-----GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGE 360
              +G  G  G     G  G   P  K GGK   G  G   R G      PP P       
Sbjct: 878  GAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSP 937

Query: 361  GGGGGSRADVTAGR----------ARPRRR-----------RWEPLRAQRSGARPGAPAP 399
            G  G + A  T G             P +R             EP +   SGA  G   P
Sbjct: 938  GADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA-SGERGP 996

Query: 400  PLPCLPPAAVCHALAG-------AGAPGGRLELGL--SPGTRLIRG-GGAAVPTAAPPAP 449
            P P  PP      LAG        GAPG     G   SPG +  RG  G A P  AP AP
Sbjct: 997  PGPMGPP-----GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAP 1051

Query: 450  LPRWGPGPLPGPTG 463
                 PGP+ GP G
Sbjct: 1052 ---GAPGPV-GPAG 1061



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 55/166 (33%), Positives = 64/166 (38%), Gaps = 37/166 (22%)

Query: 304 APSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEG 361
           AP   G  G +G  G  GV  P    G +   G +G+      P  LP PP  R G   G
Sbjct: 438 APGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP----GPTGLPGPPGERGG--PG 491

Query: 362 GGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGG 421
             G   AD  AG   P   R             G+P P  P   P         AG PG 
Sbjct: 492 SRGFPGADGVAGPKGPAGER-------------GSPGPAGPKGSPGE-------AGRPG- 530

Query: 422 RLELGLSPGTRLIRGG-GAAVP--TAAPPAPLPRWG-PGPLPGPTG 463
             E GL PG + + G  G+  P     PP P  + G PGP PGP G
Sbjct: 531 --EAGL-PGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGP-PGPPG 572



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 47/166 (28%), Positives = 58/166 (34%), Gaps = 19/166 (11%)

Query: 304 APSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGA-----PHSLPPPPPFRTGR 358
           +P E+G+ G+ G   G+   R + G     G +G     GA     P     PP F    
Sbjct: 291 SPGENGAPGQMG-PRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAV 349

Query: 359 GEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAG-AG 417
           G  G  G +     G   P+  R EP     +GA   A  P     P A   +   G AG
Sbjct: 350 GAKGEAGPQGP--RGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAG 407

Query: 418 APGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
           APG        PG R   G         PP P    G    PG  G
Sbjct: 408 APG-------FPGAR---GPSGPQGPGGPPGPKGNSGEPGAPGSKG 443



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 39/121 (32%), Positives = 43/121 (35%), Gaps = 18/121 (14%)

Query: 345 PHSLPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCL 404
           P     P    T   EG  G +      G A P  R   P        +PG P PP P  
Sbjct: 96  PDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIP-------GQPGLPGPPGPPG 148

Query: 405 PPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGP--LPGPT 462
           PP        G    GG     LS G      GG +VP    P+  PR  PGP   PGP 
Sbjct: 149 PP--------GPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSG-PRGLPGPPGAPGPQ 199

Query: 463 G 463
           G
Sbjct: 200 G 200



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 33/106 (31%), Positives = 38/106 (35%), Gaps = 33/106 (31%)

Query: 305  PSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGG 362
            P   GS G +G  G +G A PR   G     G+ G     G P  + PP P    RG  G
Sbjct: 1120 PGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLN---GLPGPIGPPGP----RGRTG 1172

Query: 363  GGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAA 408
                     AG   P                PG P PP P  PP+A
Sbjct: 1173 D--------AGPVGP----------------PGPPGPPGPPGPPSA 1194


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 65/210 (30%), Positives = 78/210 (37%), Gaps = 36/210 (17%)

Query: 279 LGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQ 338
           +GSL  +L A        +P    V  + +G+ G    +   A       G  G G    
Sbjct: 26  VGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPA-------GAAGAGPAAP 78

Query: 339 GTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPA 398
               GAP + P PPP   GR   GGGG +     G   PRR    PL        P  PA
Sbjct: 79  AE--GAPGAAPEPPP--AGRARPGGGGPQRP---GPPSPRR----PLV-------PAGPA 120

Query: 399 PPLPCLPP-----AAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRW 453
           PP   L P     A  C  +  A A     E   +P       G AA+   A P P P  
Sbjct: 121 PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEP--APAGPAKPAGPAALAARAGPGPGPGP 178

Query: 454 GPGPLPGPTGLFDLSVGVSAASSSLGSTEL 483
           GPGP PGP        G  AA +  GS  L
Sbjct: 179 GPGPGPGP----GKPAGPGAAQTLNGSAAL 204



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 53/213 (24%), Positives = 63/213 (29%), Gaps = 50/213 (23%)

Query: 296 PSPPRSLVAPSESGSAGR-----------RGGTNGVATPREKLGGKRGVGRKGQGTRLGA 344
           P+PP + + P   GSAG             G     A P +  G      R G G   G 
Sbjct: 119 PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG- 177

Query: 345 PHSLPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSG------------- 391
           P   P P P   G+  G G     + +A            +    +G             
Sbjct: 178 PGPGPGPGP---GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP 234

Query: 392 ------------ARPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGA 439
                       A P APA P P   PA    A A    P     L   PG     G   
Sbjct: 235 GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP--AGPPT 292

Query: 440 AVPTAAPPAPLPRWG-----PGPLP---GPTGL 464
           A P   PPA     G     P P P   GP G+
Sbjct: 293 AAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGV 325



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 67/288 (23%), Positives = 86/288 (29%), Gaps = 33/288 (11%)

Query: 181 PARALNSGQWSPGEGRRAALGLEE---------AGPSLEGIPSSEWDTFSRDKRSLLSSH 231
           PA A  +G  +P EG   A               GP   G PS         +R L+ + 
Sbjct: 67  PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSP--------RRPLVPAG 118

Query: 232 GSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLP 291
            +P   +          +CA         +     P   + P  P  L + +   P   P
Sbjct: 119 PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178

Query: 292 TRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPP- 350
               P P      P+  G+A    G+  +            +   G    L  P    P 
Sbjct: 179 G---PGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPG 235

Query: 351 ----PPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARP-GAPAPP---LP 402
                PPF                    A P      P  A  + ARP G PA P    P
Sbjct: 236 TVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP 295

Query: 403 CLPPAAVCHALAGAG-APGGRLELGLSPGTRLIRGGGAAVPTAAPPAP 449
            +PP A       AG AP      G   G     G GAA   AA PAP
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA---AAAPAP 340


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 107/420 (25%), Positives = 135/420 (32%), Gaps = 95/420 (22%)

Query: 122 GPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPN-----GFRPARQR 176
           GP+       ES R  R G  G  G P        + GP G   +P      GF      
Sbjct: 222 GPSGPAGKDGESGRPGRPGERGLPGPPG-------IKGPAGIPGFPGMKGHRGFDGRNGE 274

Query: 177 RTRRPARALNSGQWSPGE-------GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLS 229
           +    A  L      PGE       G R A G E   P L G   +  +  +R       
Sbjct: 275 KGETGAPGLKGENGLPGENGAPGPMGPRGAPG-ERGRPGLPGAAGARGNDGARGSDGQPG 333

Query: 230 SHGSPGTIQ-----------SSVDIPSLTNTCAGGKDKTPPF----SQEVDDPHALS-SP 273
             G PGT                  P  +N   G + +  P     +Q    P  ++ SP
Sbjct: 334 PPGPPGTAGFPGSPGAKGEVGPAGSPG-SNGAPGQRGEPGPQGHAGAQGPPGPPGINGSP 392

Query: 274 FFPKQLGSLSLE-LPARLPTRCLPSPPRSLVAPSESGSAGRRG--GTNGVATPREKLG-- 328
               ++G   +   P  +  R  P P  +  AP   G AG  G  G  G   PR + G  
Sbjct: 393 GGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEA 452

Query: 329 GKRGV-GRKGQGTRLGAP-----HSLPPP------PPFRTGRGEGGGGGSRADV----TA 372
           G  GV G KG+  + G+P     + LP        P FR   G  G  G +         
Sbjct: 453 GIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAP 512

Query: 373 GRARPRRRRWEPLR-----------------------------AQRSGARPGAPAPPLPC 403
           G A PR    EP R                             +Q    RPG P P  P 
Sbjct: 513 GPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPR 572

Query: 404 LPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
             P  +       G PG +   G +PG    RGG        PP      GP   PGPTG
Sbjct: 573 GQPGVM-------GFPGPKGNDG-APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG 624



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 109/425 (25%), Positives = 142/425 (33%), Gaps = 62/425 (14%)

Query: 108 SPSRQSETQITPAGGPAA--FCDSTAESKRQLRVGAEGKGGGPQALGR--GRRVNGPQGP 163
           SP  + E  + PAG P +        E   Q   GA+G  G P   G   G+   GP G 
Sbjct: 346 SPGAKGE--VGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGI 403

Query: 164 DRWPN--GFRPARQRRTRRPARALNSGQWSPGE----------GRRAALGLE-------E 204
              P   G R          A  L  G   PG+          G R   G+        E
Sbjct: 404 PGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGE 463

Query: 205 AG-------PSLEGIPSSEWDTFSRDKRSLLSSHGSPGTI----QSSVDIPSLTNTCAG- 252
            G       P   G+P +  +  +   R     +G PG      +     P+     AG 
Sbjct: 464 DGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGE 523

Query: 253 -GKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSA 311
            G+D  P        P +   P    + G    +  +  P    PS PR    P   G  
Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRG--QPGVMGFP 581

Query: 312 GRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVT 371
           G +G  +G      + GG  G G +G   + G      PP P        G GG + D  
Sbjct: 582 GPKGN-DGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT-------GPGGDKGDT- 632

Query: 372 AGRARPRRRRWEPLRAQRSG--ARPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSP 429
            G   P+  +  P      G   +PG P P      P A       AGAPG R   GL+ 
Sbjct: 633 -GPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAP-GGKGDAGAPGERGPPGLA- 689

Query: 430 GTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDLS--VGVSAASSSLGSTELEKNM 487
           G   +RGG      A PP P    G    PGP G        G+      LGS   + + 
Sbjct: 690 GAPGLRGG------AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDK 743

Query: 488 GSGGG 492
           G  GG
Sbjct: 744 GEPGG 748



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 97/341 (28%), Positives = 120/341 (35%), Gaps = 54/341 (15%)

Query: 140 GAEGKGGGPQALG-RGRR-VNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRR 197
           G  G  G P A G RG     GP GP+  P    PA +R    PA      + + GE  R
Sbjct: 471 GEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPA----GPRGAAGEPGR 526

Query: 198 AALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKT 257
             +     GP + G+P S     S  K       G PG+   S            G+   
Sbjct: 527 DGV---PGGPGMRGMPGSPGGPGSDGKP------GPPGSQGES------------GRPGP 565

Query: 258 PPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRG-- 315
           P  S     P  +    FP   G+     P +   R  P  P     P ++G  G +G  
Sbjct: 566 PGPSGPRGQPGVMG---FPGPKGNDGA--PGKNGERGGPGGPGPQGPPGKNGETGPQGPP 620

Query: 316 GTNGVATPREKLGGKRGVGRKGQGTRLGAP--HSLPPPPPFRTGRGEGGGGGSRADVTA- 372
           G  G    +   G     G +G     G P  +  P  P  +   G  G  G + D  A 
Sbjct: 621 GPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAP 680

Query: 373 GRARPRRRRWEPLRAQRSGARP-------GAPAPPLPCLPPAAVCHALAGAGAPGGRLEL 425
           G   P      P    R GA P       GA  PP P  P AA    L G   PG R  L
Sbjct: 681 GERGPPGLAGAP--GLRGGAGPPGPEGGKGAAGPPGP--PGAAGTPGLQGM--PGERGGL 734

Query: 426 GLSPGTRLIRGG-GAAVPTAAPPAPLPRWGPGPL--PGPTG 463
           G SPG +  +G  G       P    PR   GP+  PGP G
Sbjct: 735 G-SPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAG 774



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 77/285 (27%), Positives = 93/285 (32%), Gaps = 48/285 (16%)

Query: 207 PSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDD 266
           P   GIP    D        +    GSPG    S   P +  +C  G     P     D 
Sbjct: 111 PGPPGIPGRNGDP------GIPGQPGSPG----SPGPPGICESCPTGPQNYSPQYDSYDV 160

Query: 267 PHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRG--------GTN 318
              ++        G      PA  P    P PP +   P   GS G +G        G +
Sbjct: 161 KSGVAVG------GLAGYPGPAGPPGP--PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPS 212

Query: 319 GVATPREKLGGKRGVGRKGQGTRLGAP--HSLPPPPPFRTGRGEGGGGGSRAD-VTAGRA 375
           G   P   +G     G+ G+  R G P    LP PP  +   G  G  G +      GR 
Sbjct: 213 GPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRN 272

Query: 376 RPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIR 435
             +     P     +G  PG    P P  P           GAPG R   GL PG    R
Sbjct: 273 GEKGETGAPGLKGENGL-PGENGAPGPMGP----------RGAPGERGRPGL-PGAAGAR 320

Query: 436 GGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDLSVGVSAASSSLGS 480
           G   A  +   P P     PGP PG  G F  S G        GS
Sbjct: 321 GNDGARGSDGQPGP-----PGP-PGTAG-FPGSPGAKGEVGPAGS 358



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 36/119 (30%), Positives = 43/119 (36%), Gaps = 30/119 (25%)

Query: 304  APSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEG 361
            AP   G AG++G  G+ G A PR  +G     G+ G     G P  + PP P R  RGE 
Sbjct: 1117 APGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTS---GHPGPIGPPGP-RGNRGER 1172

Query: 362  GGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPG 420
            G  GS                           PG P PP P   P   C  +  A   G
Sbjct: 1173 GSEGSPG------------------------HPGQPGPPGPPGAPGPCCGGVGAAAIAG 1207



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 85/372 (22%), Positives = 108/372 (29%), Gaps = 79/372 (21%)

Query: 140  GAEGKGGGPQALG--RGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRR 197
            G  G  GGP A G    R + GP G +  P    P+                 SPG+   
Sbjct: 861  GERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSG----------------SPGKDGP 904

Query: 198  AALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKT 257
                     P   G+   + D     ++    + G PG     + I  +T          
Sbjct: 905  PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGA-PGPLGIAGITGARGLAGPPG 963

Query: 258  PPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRG-- 315
             P  +    P  +           LS E            PP     P  +G+AG  G  
Sbjct: 964  MPGPRGSPGPQGVKGESGKPGANGLSGER----------GPPGPQGLPGLAGTAGEPGRD 1013

Query: 316  ---GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTA 372
               G++G+       GGK   G  G     GAP    PP P       G  G S     A
Sbjct: 1014 GNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPA 1073

Query: 373  GRARPRRRRWEP-------------------LRAQRS-GARPGAPAPPLPCLPPAAVCHA 412
            G   P   R  P                   ++  R     PGAP  P     PA    A
Sbjct: 1074 GAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP----GPAGQQGA 1129

Query: 413  LAGAGAPGGRLELGLS-----------------PGTRLIRG----GGAAVPTAAPPAPLP 451
            +   G  G R  +G S                 PG R  RG     G+      P  P P
Sbjct: 1130 IGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGP 1189

Query: 452  RWGPGPLPGPTG 463
               PGP  G  G
Sbjct: 1190 PGAPGPCCGGVG 1201


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 95/344 (27%), Positives = 118/344 (34%), Gaps = 57/344 (16%)

Query: 140  GAEGKGGG--PQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-GR 196
            GA+G  GG  P      R + GPQGP+ +P    P        P      G   PG  G+
Sbjct: 773  GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP--------PGPPGKDG--LPGHPGQ 822

Query: 197  RAALGLE-----EAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCA 251
            R  +G +        P + G   +  +T    +R      G PG       +P       
Sbjct: 823  RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG----EQGLPGTAGKEG 878

Query: 252  GGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPS-PPRSLVAPSESGS 310
               D  PP +   D P  L    FP + G         L     PS PP    +P E G+
Sbjct: 879  TKGDPGPPGAPGKDGPAGLRG--FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 936

Query: 311  AGRRG--GTNGVATPREKLG--GKRGV-GRKGQGTRLG-----APHSLPPPPPFRTGRGE 360
            AG  G  G  G   P+   G  G++GV G KG     G      P  LP P       GE
Sbjct: 937  AGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE 996

Query: 361  GGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPC-LPPAAVCHALAGAGAP 419
             G  G   D      +  +    P         PG P P  P   P AA      GA  P
Sbjct: 997  DGDKGEVGDPGQKGTKGNKGEHGP---------PGPPGPIGPVGQPGAAGADGEPGARGP 1047

Query: 420  GGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
             G        GTR   G         PP P+   G   LPGP+G
Sbjct: 1048 QGHFGAKGDEGTRGFNG---------PPGPIGLQG---LPGPSG 1079



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 57/192 (29%), Positives = 70/192 (36%), Gaps = 25/192 (13%)

Query: 298  PPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLG--------APHSLP 349
            PP     P ESGS G +G   GV  PR + G K   G+ G+    G         P   P
Sbjct: 1122 PPGEKGEPGESGSPGIQGEP-GVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1180

Query: 350  PPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAV 409
             P  F    G  G GG R     G    R    EP        +PG+P P     PP  +
Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQ--DGAKGDRGEDGEP-------GQPGSPGPTGENGPPGPL 1231

Query: 410  CHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDL-- 467
                  AG+PG         G +  +G   A+       P+   GP   PGP GL  L  
Sbjct: 1232 GKR-GPAGSPGSEGR----QGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG 1286

Query: 468  SVGVSAASSSLG 479
            SVG      + G
Sbjct: 1287 SVGQQGRPGATG 1298



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 89/354 (25%), Positives = 118/354 (33%), Gaps = 75/354 (21%)

Query: 140 GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAA 199
           G +G+ G P  L  G  V GP GP                              EG    
Sbjct: 294 GLKGEKGEPAVLEPGMLVEGPPGP------------------------------EGPAGL 323

Query: 200 LGLEEAGPSLEGIPSSEWDTFSR---DKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDK 256
           +G     P ++G P    D   R    +  L  S G+PG   +S+ +P      +GG DK
Sbjct: 324 IG----PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG--SGGGDK 377

Query: 257 TPPFSQEVDDPHALSSPFFPKQLGSLSLE-LPARLPTRCLPSP---PRSLVAPSESGSAG 312
            P  + +     A+       Q   L+L   P  +     P P   P S     ESG  G
Sbjct: 378 GPVVAAQEAQAQAI------LQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG 431

Query: 313 RRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAP--------HSLPPPPPFRTGRGEGG 362
            +G  G  G+  P  K G +   G  G     G P          LP  P  +  RG+ G
Sbjct: 432 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTG 491

Query: 363 G---------GGSRADVTAGRARPRRRRWE--PLRAQRSGARPGAPAPP--LPCLPPAAV 409
                      G R D   G   PR    E  P         PG P PP       P   
Sbjct: 492 AQGLPGPPGEDGERGD--DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 549

Query: 410 CHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
             +L   G PG   + G +PGT+ + G   A+       P  + G   +PG  G
Sbjct: 550 KGSLGPQGEPGPPGQQG-TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 602



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 56/196 (28%), Positives = 69/196 (35%), Gaps = 34/196 (17%)

Query: 292  TRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPP 351
            TR    PP  +      G +G +G T  V      +G     G +G     GA     PP
Sbjct: 1059 TRGFNGPPGPIGLQGLPGPSGEKGETGDVGP----MGPPGPPGPRGPAGPNGADGPQGPP 1114

Query: 352  -------PPFRTGR-GEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPC 403
                   PP   G  GE G  G + +   G   PR  R E    +    +PG P PP P 
Sbjct: 1115 GGVGNLGPPGEKGEPGESGSPGIQGE--PGVKGPRGERGE----KGESGQPGEPGPPGPK 1168

Query: 404  LP-----PAAVCHALAGAGAPGGRLELGL--SPGTRLIRGG-------GAAVPTA--APP 447
             P     P      +   G PG   E G     G +  RG        G+  PT    PP
Sbjct: 1169 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1228

Query: 448  APLPRWGPGPLPGPTG 463
             PL + GP   PG  G
Sbjct: 1229 GPLGKRGPAGSPGSEG 1244



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 62/224 (27%), Positives = 78/224 (34%), Gaps = 59/224 (26%)

Query: 296  PSPPRSLVAPSESGSAGRRG--------GTNGVATPREKLGGKRGVGRKGQGTRLGAP-- 345
            P PP       + G  G  G        G  G   PR + G K   G  G+  + G+P  
Sbjct: 1162 PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1221

Query: 346  --HSLPPPPPFRTG-------RGEGGGGGSRADV----------------TAGRARPRRR 380
               + PP P  + G        G  GG G++ D                  AG+  P   
Sbjct: 1222 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1281

Query: 381  RWEPLRAQRSGARPGAPA---PPLPCLPPAAVCHALAG-AGAPGGRLELGL-----SPGT 431
            R  P    + G RPGA     PP P  PP      L G AGA G +   GL      PG 
Sbjct: 1282 RGLPGSVGQQG-RPGATGQAGPPGPVGPPGLP--GLRGDAGAKGEKGHPGLIGLIGPPGE 1338

Query: 432  RLIRGG-GAAVPTAAP-----------PAPLPRWGPGPLPGPTG 463
            +  +G  G   P  +P             P+   GP  LPGP G
Sbjct: 1339 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAG 1382



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 87/341 (25%), Positives = 115/341 (33%), Gaps = 63/341 (18%)

Query: 138 RVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE--- 194
           R G  G+ G P   G    + GPQGP R P G      +  RR     +  +  PG+   
Sbjct: 411 RPGPLGQPGSPGLKGESGDL-GPQGP-RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 468

Query: 195 -GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGG 253
            G R   GL    P L G      DT          + G PG                 G
Sbjct: 469 KGDRGFDGL----PGLPGEKGHRGDT---------GAQGLPGP---------------PG 500

Query: 254 KDKTPPFSQEVDDPHALSSPFFPKQL----GSLSLELPARLPTRCLPSPPRSLVAPS-ES 308
           +D       E+  P  L     P+ L    G   +  P  +     P  P+  + P  E 
Sbjct: 501 EDGERGDDGEIG-PRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 559

Query: 309 GSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPP-PFRTGRG--EGGG 363
           G  G++G  GT G+  P+  +G     G +G+    G P S  PP  P + G    +G  
Sbjct: 560 GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 619

Query: 364 GGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGRL 423
           G S      G   PR  +         G +        P              G  G R 
Sbjct: 620 GPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK--------GDIGVKGDRG 671

Query: 424 ELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGL 464
           E+G+ PG+R   G         P  P  R GP   PGP GL
Sbjct: 672 EVGV-PGSRGEDG---------PEGPKGRTGPTGDPGPPGL 702



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 60/272 (22%), Positives = 89/272 (32%), Gaps = 64/272 (23%)

Query: 140  GAEGKGGGPQALGRGRRVNGPQGP--DRWPNGFRPARQRRTRRPARALNSGQWSPGEGRR 197
            G  G+ G P   G     NGP GP   R P G   +  R+  + A+       +PG  + 
Sbjct: 1211 GEPGQPGSPGPTGE----NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG--KT 1264

Query: 198  AALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKT 257
              +G   AGP+  G P  +               G PG++               G+   
Sbjct: 1265 GPVG--PAGPA--GKPGPD------------GLRGLPGSV---------------GQQGR 1293

Query: 258  PPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGT 317
            P  + +   P  +  P  P   G    +       +  P     +  P E G  G RG  
Sbjct: 1294 PGATGQAGPPGPVGPPGLPGLRGDAGAK-----GEKGHPGLIGLIGPPGEQGEKGDRGLP 1348

Query: 318  NGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAGRARP 377
                +P +K  G+ G+         G P  LP P   +  +G  G GG + +   G   P
Sbjct: 1349 GPQGSPGQK--GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE--KGVQGP 1404

Query: 378  RRRRWEPLRAQRSGARPGAPAPPLPCLPPAAV 409
                            PG P PP   + P  +
Sbjct: 1405 ----------------PGHPGPPGEVIQPLPI 1420


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 95/344 (27%), Positives = 118/344 (34%), Gaps = 57/344 (16%)

Query: 140  GAEGKGGG--PQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-GR 196
            GA+G  GG  P      R + GPQGP+ +P    P        P      G   PG  G+
Sbjct: 752  GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP--------PGPPGKDG--LPGHPGQ 801

Query: 197  RAALGLE-----EAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCA 251
            R  +G +        P + G   +  +T    +R      G PG       +P       
Sbjct: 802  RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG----EQGLPGTAGKEG 857

Query: 252  GGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPS-PPRSLVAPSESGS 310
               D  PP +   D P  L    FP + G         L     PS PP    +P E G+
Sbjct: 858  TKGDPGPPGAPGKDGPAGLRG--FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 915

Query: 311  AGRRG--GTNGVATPREKLG--GKRGV-GRKGQGTRLG-----APHSLPPPPPFRTGRGE 360
            AG  G  G  G   P+   G  G++GV G KG     G      P  LP P       GE
Sbjct: 916  AGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE 975

Query: 361  GGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPC-LPPAAVCHALAGAGAP 419
             G  G   D      +  +    P         PG P P  P   P AA      GA  P
Sbjct: 976  DGDKGEVGDPGQKGTKGNKGEHGP---------PGPPGPIGPVGQPGAAGADGEPGARGP 1026

Query: 420  GGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
             G        GTR   G         PP P+   G   LPGP+G
Sbjct: 1027 QGHFGAKGDEGTRGFNG---------PPGPIGLQG---LPGPSG 1058



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 57/192 (29%), Positives = 70/192 (36%), Gaps = 25/192 (13%)

Query: 298  PPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLG--------APHSLP 349
            PP     P ESGS G +G   GV  PR + G K   G+ G+    G         P   P
Sbjct: 1101 PPGEKGEPGESGSPGIQGEP-GVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1159

Query: 350  PPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAV 409
             P  F    G  G GG R     G    R    EP        +PG+P P     PP  +
Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQ--DGAKGDRGEDGEP-------GQPGSPGPTGENGPPGPL 1210

Query: 410  CHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDL-- 467
                  AG+PG         G +  +G   A+       P+   GP   PGP GL  L  
Sbjct: 1211 GKR-GPAGSPGSEGR----QGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG 1265

Query: 468  SVGVSAASSSLG 479
            SVG      + G
Sbjct: 1266 SVGQQGRPGATG 1277



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 89/354 (25%), Positives = 118/354 (33%), Gaps = 75/354 (21%)

Query: 140 GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAA 199
           G +G+ G P  L  G  V GP GP                              EG    
Sbjct: 273 GLKGEKGEPAVLEPGMLVEGPPGP------------------------------EGPAGL 302

Query: 200 LGLEEAGPSLEGIPSSEWDTFSR---DKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDK 256
           +G     P ++G P    D   R    +  L  S G+PG   +S+ +P      +GG DK
Sbjct: 303 IG----PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG--SGGGDK 356

Query: 257 TPPFSQEVDDPHALSSPFFPKQLGSLSLE-LPARLPTRCLPSP---PRSLVAPSESGSAG 312
            P  + +     A+       Q   L+L   P  +     P P   P S     ESG  G
Sbjct: 357 GPVVAAQEAQAQAI------LQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG 410

Query: 313 RRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAP--------HSLPPPPPFRTGRGEGG 362
            +G  G  G+  P  K G +   G  G     G P          LP  P  +  RG+ G
Sbjct: 411 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTG 470

Query: 363 G---------GGSRADVTAGRARPRRRRWE--PLRAQRSGARPGAPAPP--LPCLPPAAV 409
                      G R D   G   PR    E  P         PG P PP       P   
Sbjct: 471 AQGLPGPPGEDGERGD--DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 528

Query: 410 CHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
             +L   G PG   + G +PGT+ + G   A+       P  + G   +PG  G
Sbjct: 529 KGSLGPQGEPGPPGQQG-TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 56/196 (28%), Positives = 69/196 (35%), Gaps = 34/196 (17%)

Query: 292  TRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPP 351
            TR    PP  +      G +G +G T  V      +G     G +G     GA     PP
Sbjct: 1038 TRGFNGPPGPIGLQGLPGPSGEKGETGDVGP----MGPPGPPGPRGPAGPNGADGPQGPP 1093

Query: 352  -------PPFRTGR-GEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPC 403
                   PP   G  GE G  G + +   G   PR  R E    +    +PG P PP P 
Sbjct: 1094 GGVGNLGPPGEKGEPGESGSPGIQGE--PGVKGPRGERGE----KGESGQPGEPGPPGPK 1147

Query: 404  LP-----PAAVCHALAGAGAPGGRLELGL--SPGTRLIRGG-------GAAVPTA--APP 447
             P     P      +   G PG   E G     G +  RG        G+  PT    PP
Sbjct: 1148 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1207

Query: 448  APLPRWGPGPLPGPTG 463
             PL + GP   PG  G
Sbjct: 1208 GPLGKRGPAGSPGSEG 1223



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 62/224 (27%), Positives = 78/224 (34%), Gaps = 59/224 (26%)

Query: 296  PSPPRSLVAPSESGSAGRRG--------GTNGVATPREKLGGKRGVGRKGQGTRLGAP-- 345
            P PP       + G  G  G        G  G   PR + G K   G  G+  + G+P  
Sbjct: 1141 PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1200

Query: 346  --HSLPPPPPFRTG-------RGEGGGGGSRADV----------------TAGRARPRRR 380
               + PP P  + G        G  GG G++ D                  AG+  P   
Sbjct: 1201 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1260

Query: 381  RWEPLRAQRSGARPGAPA---PPLPCLPPAAVCHALAG-AGAPGGRLELGL-----SPGT 431
            R  P    + G RPGA     PP P  PP      L G AGA G +   GL      PG 
Sbjct: 1261 RGLPGSVGQQG-RPGATGQAGPPGPVGPPGLP--GLRGDAGAKGEKGHPGLIGLIGPPGE 1317

Query: 432  RLIRGG-GAAVPTAAP-----------PAPLPRWGPGPLPGPTG 463
            +  +G  G   P  +P             P+   GP  LPGP G
Sbjct: 1318 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAG 1361



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 87/341 (25%), Positives = 115/341 (33%), Gaps = 63/341 (18%)

Query: 138 RVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE--- 194
           R G  G+ G P   G    + GPQGP R P G      +  RR     +  +  PG+   
Sbjct: 390 RPGPLGQPGSPGLKGESGDL-GPQGP-RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 447

Query: 195 -GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGG 253
            G R   GL    P L G      DT          + G PG                 G
Sbjct: 448 KGDRGFDGL----PGLPGEKGHRGDT---------GAQGLPGP---------------PG 479

Query: 254 KDKTPPFSQEVDDPHALSSPFFPKQL----GSLSLELPARLPTRCLPSPPRSLVAPS-ES 308
           +D       E+  P  L     P+ L    G   +  P  +     P  P+  + P  E 
Sbjct: 480 EDGERGDDGEIG-PRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 538

Query: 309 GSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPP-PFRTGRG--EGGG 363
           G  G++G  GT G+  P+  +G     G +G+    G P S  PP  P + G    +G  
Sbjct: 539 GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 598

Query: 364 GGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGRL 423
           G S      G   PR  +         G +        P              G  G R 
Sbjct: 599 GPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK--------GDIGVKGDRG 650

Query: 424 ELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGL 464
           E+G+ PG+R   G         P  P  R GP   PGP GL
Sbjct: 651 EVGV-PGSRGEDG---------PEGPKGRTGPTGDPGPPGL 681



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 60/272 (22%), Positives = 89/272 (32%), Gaps = 64/272 (23%)

Query: 140  GAEGKGGGPQALGRGRRVNGPQGP--DRWPNGFRPARQRRTRRPARALNSGQWSPGEGRR 197
            G  G+ G P   G     NGP GP   R P G   +  R+  + A+       +PG  + 
Sbjct: 1190 GEPGQPGSPGPTGE----NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG--KT 1243

Query: 198  AALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKT 257
              +G   AGP+  G P  +               G PG++               G+   
Sbjct: 1244 GPVG--PAGPA--GKPGPD------------GLRGLPGSV---------------GQQGR 1272

Query: 258  PPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGT 317
            P  + +   P  +  P  P   G    +       +  P     +  P E G  G RG  
Sbjct: 1273 PGATGQAGPPGPVGPPGLPGLRGDAGAK-----GEKGHPGLIGLIGPPGEQGEKGDRGLP 1327

Query: 318  NGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAGRARP 377
                +P +K  G+ G+         G P  LP P   +  +G  G GG + +   G   P
Sbjct: 1328 GPQGSPGQK--GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE--KGVQGP 1383

Query: 378  RRRRWEPLRAQRSGARPGAPAPPLPCLPPAAV 409
                            PG P PP   + P  +
Sbjct: 1384 ----------------PGHPGPPGEVIQPLPI 1399


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 95/344 (27%), Positives = 118/344 (34%), Gaps = 57/344 (16%)

Query: 140  GAEGKGGG--PQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-GR 196
            GA+G  GG  P      R + GPQGP+ +P    P        P      G   PG  G+
Sbjct: 859  GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP--------PGPPGKDG--LPGHPGQ 908

Query: 197  RAALGLE-----EAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCA 251
            R  +G +        P + G   +  +T    +R      G PG       +P       
Sbjct: 909  RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG----EQGLPGTAGKEG 964

Query: 252  GGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPS-PPRSLVAPSESGS 310
               D  PP +   D P  L    FP + G         L     PS PP    +P E G+
Sbjct: 965  TKGDPGPPGAPGKDGPAGLRG--FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 1022

Query: 311  AGRRG--GTNGVATPREKLG--GKRGV-GRKGQGTRLG-----APHSLPPPPPFRTGRGE 360
            AG  G  G  G   P+   G  G++GV G KG     G      P  LP P       GE
Sbjct: 1023 AGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE 1082

Query: 361  GGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPC-LPPAAVCHALAGAGAP 419
             G  G   D      +  +    P         PG P P  P   P AA      GA  P
Sbjct: 1083 DGDKGEVGDPGQKGTKGNKGEHGP---------PGPPGPIGPVGQPGAAGADGEPGARGP 1133

Query: 420  GGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
             G        GTR   G         PP P+   G   LPGP+G
Sbjct: 1134 QGHFGAKGDEGTRGFNG---------PPGPIGLQG---LPGPSG 1165



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 57/192 (29%), Positives = 70/192 (36%), Gaps = 25/192 (13%)

Query: 298  PPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLG--------APHSLP 349
            PP     P ESGS G +G   GV  PR + G K   G+ G+    G         P   P
Sbjct: 1208 PPGEKGEPGESGSPGIQGEP-GVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1266

Query: 350  PPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAV 409
             P  F    G  G GG R     G    R    EP        +PG+P P     PP  +
Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQ--DGAKGDRGEDGEP-------GQPGSPGPTGENGPPGPL 1317

Query: 410  CHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDL-- 467
                  AG+PG         G +  +G   A+       P+   GP   PGP GL  L  
Sbjct: 1318 GKR-GPAGSPGSEGR----QGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG 1372

Query: 468  SVGVSAASSSLG 479
            SVG      + G
Sbjct: 1373 SVGQQGRPGATG 1384



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 96/383 (25%), Positives = 129/383 (33%), Gaps = 80/383 (20%)

Query: 112 QSETQITPA-GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGF 170
           + ET++ PA     A   + A   R    G +G+ G P  L  G  V GP GP       
Sbjct: 355 REETELGPALSAETAHSGAAAHGPR----GLKGEKGEPAVLEPGMLVEGPPGP------- 403

Query: 171 RPARQRRTRRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSR---DKRSL 227
                                  EG    +G     P ++G P    D   R    +  L
Sbjct: 404 -----------------------EGPAGLIG----PPGIQGNPGPVGDPGERGPPGRAGL 436

Query: 228 LSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLE-L 286
             S G+PG   +S+ +P      +GG DK P  + +     A+       Q   L+L   
Sbjct: 437 PGSDGAPGPPGTSLMLPFRFG--SGGGDKGPVVAAQEAQAQAI------LQQARLALRGP 488

Query: 287 PARLPTRCLPSP---PRSLVAPSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTR 341
           P  +     P P   P S     ESG  G +G  G  G+  P  K G +   G  G    
Sbjct: 489 PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGM 548

Query: 342 LGAP--------HSLPPPPPFRTGRGEGGG---------GGSRADVTAGRARPRRRRWE- 383
            G P          LP  P  +  RG+ G           G R D   G   PR    E 
Sbjct: 549 PGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD--DGEIGPRGLPGES 606

Query: 384 -PLRAQRSGARPGAPAPP--LPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAA 440
            P         PG P PP       P     +L   G PG   + G +PGT+ + G   A
Sbjct: 607 GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG-TPGTQGLPGPQGA 665

Query: 441 VPTAAPPAPLPRWGPGPLPGPTG 463
           +       P  + G   +PG  G
Sbjct: 666 IGPHGEKGPQGKPGLPGMPGSDG 688



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 56/196 (28%), Positives = 69/196 (35%), Gaps = 34/196 (17%)

Query: 292  TRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPP 351
            TR    PP  +      G +G +G T  V      +G     G +G     GA     PP
Sbjct: 1145 TRGFNGPPGPIGLQGLPGPSGEKGETGDVGP----MGPPGPPGPRGPAGPNGADGPQGPP 1200

Query: 352  -------PPFRTGR-GEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPC 403
                   PP   G  GE G  G + +   G   PR  R E    +    +PG P PP P 
Sbjct: 1201 GGVGNLGPPGEKGEPGESGSPGIQGE--PGVKGPRGERGE----KGESGQPGEPGPPGPK 1254

Query: 404  LP-----PAAVCHALAGAGAPGGRLELGL--SPGTRLIRGG-------GAAVPTA--APP 447
             P     P      +   G PG   E G     G +  RG        G+  PT    PP
Sbjct: 1255 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1314

Query: 448  APLPRWGPGPLPGPTG 463
             PL + GP   PG  G
Sbjct: 1315 GPLGKRGPAGSPGSEG 1330



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 62/224 (27%), Positives = 78/224 (34%), Gaps = 59/224 (26%)

Query: 296  PSPPRSLVAPSESGSAGRRG--------GTNGVATPREKLGGKRGVGRKGQGTRLGAP-- 345
            P PP       + G  G  G        G  G   PR + G K   G  G+  + G+P  
Sbjct: 1248 PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1307

Query: 346  --HSLPPPPPFRTG-------RGEGGGGGSRADV----------------TAGRARPRRR 380
               + PP P  + G        G  GG G++ D                  AG+  P   
Sbjct: 1308 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1367

Query: 381  RWEPLRAQRSGARPGAPA---PPLPCLPPAAVCHALAG-AGAPGGRLELGL-----SPGT 431
            R  P    + G RPGA     PP P  PP      L G AGA G +   GL      PG 
Sbjct: 1368 RGLPGSVGQQG-RPGATGQAGPPGPVGPPGLP--GLRGDAGAKGEKGHPGLIGLIGPPGE 1424

Query: 432  RLIRGG-GAAVPTAAP-----------PAPLPRWGPGPLPGPTG 463
            +  +G  G   P  +P             P+   GP  LPGP G
Sbjct: 1425 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAG 1468



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 87/341 (25%), Positives = 115/341 (33%), Gaps = 63/341 (18%)

Query: 138 RVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE--- 194
           R G  G+ G P   G    + GPQGP R P G      +  RR     +  +  PG+   
Sbjct: 497 RPGPLGQPGSPGLKGESGDL-GPQGP-RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 554

Query: 195 -GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGG 253
            G R   GL    P L G      DT          + G PG                 G
Sbjct: 555 KGDRGFDGL----PGLPGEKGHRGDT---------GAQGLPGP---------------PG 586

Query: 254 KDKTPPFSQEVDDPHALSSPFFPKQL----GSLSLELPARLPTRCLPSPPRSLVAPS-ES 308
           +D       E+  P  L     P+ L    G   +  P  +     P  P+  + P  E 
Sbjct: 587 EDGERGDDGEIG-PRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 645

Query: 309 GSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPP-PFRTGRG--EGGG 363
           G  G++G  GT G+  P+  +G     G +G+    G P S  PP  P + G    +G  
Sbjct: 646 GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 705

Query: 364 GGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGRL 423
           G S      G   PR  +         G +        P              G  G R 
Sbjct: 706 GPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK--------GDIGVKGDRG 757

Query: 424 ELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGL 464
           E+G+ PG+R   G         P  P  R GP   PGP GL
Sbjct: 758 EVGV-PGSRGEDG---------PEGPKGRTGPTGDPGPPGL 788



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 60/272 (22%), Positives = 89/272 (32%), Gaps = 64/272 (23%)

Query: 140  GAEGKGGGPQALGRGRRVNGPQGP--DRWPNGFRPARQRRTRRPARALNSGQWSPGEGRR 197
            G  G+ G P   G     NGP GP   R P G   +  R+  + A+       +PG  + 
Sbjct: 1297 GEPGQPGSPGPTGE----NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG--KT 1350

Query: 198  AALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKT 257
              +G   AGP+  G P  +               G PG++               G+   
Sbjct: 1351 GPVG--PAGPA--GKPGPD------------GLRGLPGSV---------------GQQGR 1379

Query: 258  PPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGT 317
            P  + +   P  +  P  P   G    +       +  P     +  P E G  G RG  
Sbjct: 1380 PGATGQAGPPGPVGPPGLPGLRGDAGAK-----GEKGHPGLIGLIGPPGEQGEKGDRGLP 1434

Query: 318  NGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAGRARP 377
                +P +K  G+ G+         G P  LP P   +  +G  G GG + +   G   P
Sbjct: 1435 GPQGSPGQK--GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE--KGVQGP 1490

Query: 378  RRRRWEPLRAQRSGARPGAPAPPLPCLPPAAV 409
                            PG P PP   + P  +
Sbjct: 1491 ----------------PGHPGPPGEVIQPLPI 1506


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 93/335 (27%), Positives = 118/335 (35%), Gaps = 81/335 (24%)

Query: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240
           PA A  +   SP  GRR +L     GP L G                LS    PG   +S
Sbjct: 95  PAPASPARPVSPAPGRRLSLWAVPPGPPLSG---------------GLSPDPKPGGAPTS 139

Query: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSP-P 299
              P L++   GG +   P  +        SSP      G+ S  L    P    P+P P
Sbjct: 140 SRRPLLSSPSWGGPE---PEGRAGGGIPGSSSP----HPGTGSRRLKVAPPP---PAPKP 189

Query: 300 RSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRG 359
              V  S + + G +G  + ++ P  +  GK  V  KG  +  G   S+           
Sbjct: 190 CKTVTTSGAKAGGGKGAGSRLSWPESE--GKPRV--KGSKSSAGTGASVSA----AATAA 241

Query: 360 EGGGGGSRADVTAG-------RARPRRRRWEPLRAQRSGARPGAPA--PP---LPCLPPA 407
             GGGGS A  + G       R +   R+ +      S   PG PA  PP   LP  P  
Sbjct: 242 AAGGGGSTASTSGGVGAGAGARGKLSPRKGKSKTLDNSDLHPGPPAGSPPPLTLPPTPSP 301

Query: 408 AVCHALAGAGAPGGRLELGL---SPGTRLIRGGGAA----------------VPTAAPPA 448
           A     A A  PG    + L   +PG +  R GG A                  T  PP 
Sbjct: 302 ATAVTAASAQPPGPAPPITLEPPAPGLKRGREGGRASTRDRKMLKFISGIFTKSTGGPP- 360

Query: 449 PLPRWGPGPLPGPTGLFDLSVGVSAASSSLGSTEL 483
                G GPLPGP  L          SS  GS EL
Sbjct: 361 -----GSGPLPGPPSL----------SSGSGSREL 380



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 45/156 (28%), Positives = 55/156 (35%), Gaps = 31/156 (19%)

Query: 347 SLPPPPPFRTGRGEGGGGGSRADV-----TAGRARPRRRRWEPLRAQR-------SGARP 394
           S+PPPPP  +    G  G   ++        G   P ++R E L  ++       S A  
Sbjct: 26  SVPPPPPSPSAAAAGAAGARGSETGDPGSPRGAEEPGKKRHERLFHRQDALWISTSSAGT 85

Query: 395 GAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWG 454
           G   PP   L PA    A   + APG RL L                  A PP P    G
Sbjct: 86  GGAEPP--ALSPAPASPARPVSPAPGRRLSLW-----------------AVPPGPPLSGG 126

Query: 455 PGPLPGPTGLFDLSVGVSAASSSLGSTELEKNMGSG 490
             P P P G    S     +S S G  E E   G G
Sbjct: 127 LSPDPKPGGAPTSSRRPLLSSPSWGGPEPEGRAGGG 162


>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
            sapiens]
          Length = 1899

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 73/251 (29%), Positives = 90/251 (35%), Gaps = 55/251 (21%)

Query: 255  DKTPPFSQEVDDPHALSSPFFPKQLGSLSLE-------LPARLPTRCLPSPPRSLVAPSE 307
            D  PP  Q    P   +    P + G   ++       LP R  T  LP PP  +  P +
Sbjct: 1617 DIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD 1676

Query: 308  SGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGG 365
             G  G+ G  G  G   P    G     G  G+  + G  H  P P      +GE G  G
Sbjct: 1677 RGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG-DHGRPGPSGL---KGEKGDRG 1732

Query: 366  SRADVTAGRARPRR----------RRWE------PLRAQRSGARPGAPAPPLPCLPPAAV 409
              A     RA  R+           R+       P   Q S  +PG P PP P  P +A 
Sbjct: 1733 DIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP--PGSA- 1789

Query: 410  CHALAGAGAPGGRL-------------ELGLSPGTRLIRGGGAAVPTAAPPAPLP----R 452
                 G   PGGR              E GL PG +  RG G++ P   P  P P    R
Sbjct: 1790 --GARGEPGPGGRPGFPGTPGMQGPPGERGL-PGEKGERGTGSSGPRGLPGPPGPQGESR 1846

Query: 453  WGPGPLPGPTG 463
             GP   PG TG
Sbjct: 1847 TGP---PGSTG 1854



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 50/170 (29%), Positives = 59/170 (34%), Gaps = 31/170 (18%)

Query: 296  PSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFR 355
            P PP     P   G  G RG +  +  P     G RG         +G P    PP    
Sbjct: 1585 PGPPGPAGGPGAKGPRGERGISGAIGPP-----GPRG--------DIGPPGPQGPP---- 1627

Query: 356  TGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPA-AVCHALA 414
               G  G  G       GR   +    EP    R+G  PG P PP P  PP         
Sbjct: 1628 ---GPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGT-PGLPGPPGPMGPPGDRGFTGKD 1683

Query: 415  GAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGL 464
            GA  P G      SPG+  + G     P+  P  P    G    PGP+GL
Sbjct: 1684 GAMGPRGPPGPPGSPGSPGVTG-----PSGKPGKP----GDHGRPGPSGL 1724


>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
            sapiens]
          Length = 3063

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 73/251 (29%), Positives = 90/251 (35%), Gaps = 55/251 (21%)

Query: 255  DKTPPFSQEVDDPHALSSPFFPKQLGSLSLE-------LPARLPTRCLPSPPRSLVAPSE 307
            D  PP  Q    P   +    P + G   ++       LP R  T  LP PP  +  P +
Sbjct: 2781 DIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD 2840

Query: 308  SGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGG 365
             G  G+ G  G  G   P    G     G  G+  + G  H  P P      +GE G  G
Sbjct: 2841 RGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG-DHGRPGPSGL---KGEKGDRG 2896

Query: 366  SRADVTAGRARPRR----------RRWE------PLRAQRSGARPGAPAPPLPCLPPAAV 409
              A     RA  R+           R+       P   Q S  +PG P PP P  P +A 
Sbjct: 2897 DIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP--PGSA- 2953

Query: 410  CHALAGAGAPGGRL-------------ELGLSPGTRLIRGGGAAVPTAAPPAPLP----R 452
                 G   PGGR              E GL PG +  RG G++ P   P  P P    R
Sbjct: 2954 --GARGEPGPGGRPGFPGTPGMQGPPGERGL-PGEKGERGTGSSGPRGLPGPPGPQGESR 3010

Query: 453  WGPGPLPGPTG 463
             GP   PG TG
Sbjct: 3011 TGP---PGSTG 3018



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 50/170 (29%), Positives = 59/170 (34%), Gaps = 31/170 (18%)

Query: 296  PSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFR 355
            P PP     P   G  G RG +  +  P     G RG         +G P    PP    
Sbjct: 2749 PGPPGPAGGPGAKGPRGERGISGAIGPP-----GPRG--------DIGPPGPQGPP---- 2791

Query: 356  TGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPA-AVCHALA 414
               G  G  G       GR   +    EP    R+G  PG P PP P  PP         
Sbjct: 2792 ---GPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGT-PGLPGPPGPMGPPGDRGFTGKD 2847

Query: 415  GAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGL 464
            GA  P G      SPG+  + G     P+  P  P    G    PGP+GL
Sbjct: 2848 GAMGPRGPPGPPGSPGSPGVTG-----PSGKPGKP----GDHGRPGPSGL 2888


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 88/343 (25%), Positives = 105/343 (30%), Gaps = 49/343 (14%)

Query: 140 GAEGKGGGPQALGRGRRV--NGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRR 197
           GA+G+ G P   G       NG  GP   P G    R R     A         PG    
Sbjct: 297 GAKGEAGAPGVKGESGSPGENGSPGP-MGPRGLPGERGRTGPAGAAGARGNDGQPGPAGP 355

Query: 198 AALGLEEAGPSLEGIPSSEWD---TFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGK 254
                   GP   G P ++ +   T +R         G PGT  S     +  N    G 
Sbjct: 356 PGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP---GT 412

Query: 255 DKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAP-------SE 307
           D  P        P    +P FP   G               P  P+    P        E
Sbjct: 413 DGIPGAKGSAGAPGIAGAPGFPGPRG---------------PPGPQGATGPLGPKGQTGE 457

Query: 308 SGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPP--PPPFRTGRGEGGG 363
            G AG +G  G  G   P    G     G +G+    G P  + P  PP  R   G  G 
Sbjct: 458 PGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 517

Query: 364 GGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGRL 423
            G   D  AG       R     A   GA      P  P LP A       G   P G++
Sbjct: 518 PGQ--DGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKV 575

Query: 424 ELGLSPGTRLIRGGGAAVPTAAPPAPL-PRWGPGPL--PGPTG 463
               +PG     G         PP P   R  PG +  PGP G
Sbjct: 576 GPSGAPGEDGRPG---------PPGPQGARGQPGVMGFPGPKG 609



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 58/181 (32%), Positives = 63/181 (34%), Gaps = 28/181 (15%)

Query: 296  PSPPRSLVAPSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPP 353
            P P     AP   G  G  G  G  G   P    G     GR G     G P    PP P
Sbjct: 863  PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP 922

Query: 354  F-----RTGRGEGGGGGSRADV-TAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPA 407
                  +  RG+ G  G   +    G A P   + EP     SGA  G P P        
Sbjct: 923  SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE-GPPGP-------- 973

Query: 408  AVCHALAG----AGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
                 LAG     G PG R E G  PG  L    G      AP A   R  PGP+ GP G
Sbjct: 974  ---QGLAGQRGIVGLPGQRGERGF-PG--LPGPSGEPGKQGAPGASGDRGPPGPV-GPPG 1026

Query: 464  L 464
            L
Sbjct: 1027 L 1027



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 98/401 (24%), Positives = 120/401 (29%), Gaps = 76/401 (18%)

Query: 122  GPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTR-- 179
            GPA F        +    G +G+ G     G      GPQGP   P    P      +  
Sbjct: 831  GPAGFAGPPGADGQPGAKGEQGEAGQKGDAG----APGPQGPSGAPGPQGPTGVTGPKGA 886

Query: 180  RPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQS 239
            R A+        PG   R         P   G P        +  R      G PG    
Sbjct: 887  RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG---DSGPPGRAGE 943

Query: 240  SVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLS--LELPARLPTRCLPS 297
                P L        +K  P     D P     P  P+ L      + LP +   R  P 
Sbjct: 944  ----PGLQGPAGPPGEKGEPGD---DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 996

Query: 298  PPRSLVAPSESGSAGRRG--------GTNGVATPREKLG--------------GKRGV-G 334
             P     P + G+ G  G        G  G+  P  + G              G  GV G
Sbjct: 997  LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 1056

Query: 335  RKGQGTRLGAPHSLPPP----PPFRTG----RGEGGGGGSRADVTAGRAR----PRRRRW 382
             +G+   +GAP +  PP    P   TG    RGE G  G         AR    P+  R 
Sbjct: 1057 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116

Query: 383  EPLRAQRSGAR-----------PGAPAPPLPCLPPAAVCHA-LAGAGAPGGRLELGLSPG 430
            +   A   G R            G P PP P     A   A  +G   P G +      G
Sbjct: 1117 DKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDG 1176

Query: 431  TRLIRG----------GGAAVPTAAPPAPLPRWGPGPLPGP 461
               I G           G   P   P  P P   PGP PGP
Sbjct: 1177 ANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP-PGP 1216



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 86/347 (24%), Positives = 104/347 (29%), Gaps = 69/347 (19%)

Query: 140 GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAA 199
           GA G  G P   G      GP GP   P G R  +        + L      PGEG +  
Sbjct: 624 GAPGLRGLPGKDGETGAA-GPPGP-AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 681

Query: 200 LGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGT--IQSSVDIPSLTNTCAGGKDKT 257
              ++  P   G P        R +R      GSPG   +Q    +P    T        
Sbjct: 682 ---DQGVPGEAGAPGL---VGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT-------- 727

Query: 258 PPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGT 317
                  D P   S P                        PP +   P   G  G RG  
Sbjct: 728 -------DGPKGASGP----------------------AGPPGAQGPPGLQGMPGERGAA 758

Query: 318 NGVATPREKLG-----GKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTA 372
            G+A P+   G     G  G   K  G  L  P   P P      +GE G  G      A
Sbjct: 759 -GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGA 817

Query: 373 GRARPRRRRWEPLRAQRSGARPGAPAPP--------LPCLPPAAVCHALAGAGAPGGRLE 424
             A   R    P         PGA   P              A        +GAPG +  
Sbjct: 818 RGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGP 877

Query: 425 LGLS--PGTRLIRG--GGAAVPTAA----PPAPLPRWGPGPLPGPTG 463
            G++   G R  +G  G    P AA    PP      GP   PGP+G
Sbjct: 878 TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSG 924



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 61/241 (25%), Positives = 79/241 (32%), Gaps = 34/241 (14%)

Query: 267 PHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRG--GTNGVATPR 324
           P     P  P  L + S + P     +  P   + +V P   G  G +G  G  G    R
Sbjct: 81  PFGECCPICPTDLATASGQ-PGPKGQKGEPGDIKDIVGPK--GPPGPQGPAGEQGPRGDR 137

Query: 325 EKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEP 384
              G K   G +G+    G P +  PP P       G GG   A +  G         E 
Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFD-------EK 190

Query: 385 LRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTA 444
               + G   G   P  P  PP         AGAPG +   G +PG     G    +   
Sbjct: 191 AGGAQLGVMQGPMGPMGPRGPPGP-------AGAPGPQGFQG-NPGEPGEPGVSGPMGPR 242

Query: 445 APPAPLPRWG-------PGPL-----PGPTGL--FDLSVGVSAASSSLGSTELEKNMGSG 490
            PP P  + G       PG       PGP G   F  + G+       G   L+   G  
Sbjct: 243 GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA 302

Query: 491 G 491
           G
Sbjct: 303 G 303



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 39/127 (30%), Positives = 44/127 (34%), Gaps = 17/127 (13%)

Query: 305  PSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGG 362
            P E G  G RG  G  G+  P    G +   G  G     G P  + P        G+ G
Sbjct: 1124 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPS-------GKDG 1176

Query: 363  GGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGR 422
              G    +  G   PR R  E   A      PG P PP P  PP       A AG   G 
Sbjct: 1177 ANGIPGPI--GPPGPRGRSGETGPA----GPPGNPGPPGPPGPPGPGIDMSAFAGL--GP 1228

Query: 423  LELGLSP 429
             E G  P
Sbjct: 1229 REKGPDP 1235



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 14/101 (13%)

Query: 296  PSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFR 355
            PS PR    P   G +G+  G NG+  P   +G     GR G+    G P +  PP    
Sbjct: 1159 PSGPRG--PPGPVGPSGK-DGANGIPGP---IGPPGPRGRSGETGPAGPPGNPGPP---- 1208

Query: 356  TGRGEGGGGGSRADVTA-GRARPRRRRWEPLRAQRSGARPG 395
               G  G  G   D++A     PR +  +PL+  R+    G
Sbjct: 1209 ---GPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAG 1246


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 88/343 (25%), Positives = 105/343 (30%), Gaps = 49/343 (14%)

Query: 140 GAEGKGGGPQALGRGRRV--NGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRR 197
           GA+G+ G P   G       NG  GP   P G    R R     A         PG    
Sbjct: 228 GAKGEAGAPGVKGESGSPGENGSPGP-MGPRGLPGERGRTGPAGAAGARGNDGQPGPAGP 286

Query: 198 AALGLEEAGPSLEGIPSSEWD---TFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGK 254
                   GP   G P ++ +   T +R         G PGT  S     +  N    G 
Sbjct: 287 PGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP---GT 343

Query: 255 DKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAP-------SE 307
           D  P        P    +P FP   G               P  P+    P        E
Sbjct: 344 DGIPGAKGSAGAPGIAGAPGFPGPRG---------------PPGPQGATGPLGPKGQTGE 388

Query: 308 SGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPP--PPPFRTGRGEGGG 363
            G AG +G  G  G   P    G     G +G+    G P  + P  PP  R   G  G 
Sbjct: 389 PGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 448

Query: 364 GGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGRL 423
            G   D  AG       R     A   GA      P  P LP A       G   P G++
Sbjct: 449 PGQ--DGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKV 506

Query: 424 ELGLSPGTRLIRGGGAAVPTAAPPAPL-PRWGPGPL--PGPTG 463
               +PG     G         PP P   R  PG +  PGP G
Sbjct: 507 GPSGAPGEDGRPG---------PPGPQGARGQPGVMGFPGPKG 540



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 58/181 (32%), Positives = 63/181 (34%), Gaps = 28/181 (15%)

Query: 296 PSPPRSLVAPSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPP 353
           P P     AP   G  G  G  G  G   P    G     GR G     G P    PP P
Sbjct: 794 PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP 853

Query: 354 F-----RTGRGEGGGGGSRADV-TAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPA 407
                 +  RG+ G  G   +    G A P   + EP     SGA  G P P        
Sbjct: 854 SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE-GPPGP-------- 904

Query: 408 AVCHALAG----AGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
                LAG     G PG R E G  PG  L    G      AP A   R  PGP+ GP G
Sbjct: 905 ---QGLAGQRGIVGLPGQRGERGF-PG--LPGPSGEPGKQGAPGASGDRGPPGPV-GPPG 957

Query: 464 L 464
           L
Sbjct: 958 L 958



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 98/401 (24%), Positives = 120/401 (29%), Gaps = 76/401 (18%)

Query: 122  GPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTR-- 179
            GPA F        +    G +G+ G     G      GPQGP   P    P      +  
Sbjct: 762  GPAGFAGPPGADGQPGAKGEQGEAGQKGDAG----APGPQGPSGAPGPQGPTGVTGPKGA 817

Query: 180  RPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQS 239
            R A+        PG   R         P   G P        +  R      G PG    
Sbjct: 818  RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG---DSGPPGRAGE 874

Query: 240  SVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLS--LELPARLPTRCLPS 297
                P L        +K  P     D P     P  P+ L      + LP +   R  P 
Sbjct: 875  ----PGLQGPAGPPGEKGEPGD---DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 927

Query: 298  PPRSLVAPSESGSAGRRG--------GTNGVATPREKLG--------------GKRGV-G 334
             P     P + G+ G  G        G  G+  P  + G              G  GV G
Sbjct: 928  LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987

Query: 335  RKGQGTRLGAPHSLPPP----PPFRTG----RGEGGGGGSRADVTAGRAR----PRRRRW 382
             +G+   +GAP +  PP    P   TG    RGE G  G         AR    P+  R 
Sbjct: 988  DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047

Query: 383  EPLRAQRSGAR-----------PGAPAPPLPCLPPAAVCHA-LAGAGAPGGRLELGLSPG 430
            +   A   G R            G P PP P     A   A  +G   P G +      G
Sbjct: 1048 DKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDG 1107

Query: 431  TRLIRG----------GGAAVPTAAPPAPLPRWGPGPLPGP 461
               I G           G   P   P  P P   PGP PGP
Sbjct: 1108 ANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP-PGP 1147



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 86/347 (24%), Positives = 104/347 (29%), Gaps = 69/347 (19%)

Query: 140 GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAA 199
           GA G  G P   G      GP GP   P G R  +        + L      PGEG +  
Sbjct: 555 GAPGLRGLPGKDGETGAA-GPPGP-AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 612

Query: 200 LGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGT--IQSSVDIPSLTNTCAGGKDKT 257
              ++  P   G P        R +R      GSPG   +Q    +P    T        
Sbjct: 613 ---DQGVPGEAGAPGL---VGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT-------- 658

Query: 258 PPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGT 317
                  D P   S P                        PP +   P   G  G RG  
Sbjct: 659 -------DGPKGASGP----------------------AGPPGAQGPPGLQGMPGERGAA 689

Query: 318 NGVATPREKLG-----GKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTA 372
            G+A P+   G     G  G   K  G  L  P   P P      +GE G  G      A
Sbjct: 690 -GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGA 748

Query: 373 GRARPRRRRWEPLRAQRSGARPGAPAPP--------LPCLPPAAVCHALAGAGAPGGRLE 424
             A   R    P         PGA   P              A        +GAPG +  
Sbjct: 749 RGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGP 808

Query: 425 LGLS--PGTRLIRG--GGAAVPTAA----PPAPLPRWGPGPLPGPTG 463
            G++   G R  +G  G    P AA    PP      GP   PGP+G
Sbjct: 809 TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSG 855



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 55/212 (25%), Positives = 70/212 (33%), Gaps = 33/212 (15%)

Query: 296 PSPPRSLVAPSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPP 353
           P   + +V P   G  G +G  G  G    R   G K   G +G+    G P +  PP P
Sbjct: 40  PGDIKDIVGPK--GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGP 97

Query: 354 FRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHAL 413
                  G GG   A +  G         E     + G   G   P  P  PP       
Sbjct: 98  PGPPGPPGLGGNFAAQMAGGFD-------EKAGGAQLGVMQGPMGPMGPRGPPGP----- 145

Query: 414 AGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWG-------PGPL-----PGP 461
             AGAPG +   G +PG     G    +    PP P  + G       PG       PGP
Sbjct: 146 --AGAPGPQGFQG-NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 202

Query: 462 TGL--FDLSVGVSAASSSLGSTELEKNMGSGG 491
            G   F  + G+       G   L+   G  G
Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 234



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 39/127 (30%), Positives = 44/127 (34%), Gaps = 17/127 (13%)

Query: 305  PSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGG 362
            P E G  G RG  G  G+  P    G +   G  G     G P  + P        G+ G
Sbjct: 1055 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPS-------GKDG 1107

Query: 363  GGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGR 422
              G    +  G   PR R  E   A      PG P PP P  PP       A AG   G 
Sbjct: 1108 ANGIPGPI--GPPGPRGRSGETGPA----GPPGNPGPPGPPGPPGPGIDMSAFAGL--GP 1159

Query: 423  LELGLSP 429
             E G  P
Sbjct: 1160 REKGPDP 1166



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 14/101 (13%)

Query: 296  PSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFR 355
            PS PR    P   G +G+  G NG+  P   +G     GR G+    G P +  PP    
Sbjct: 1090 PSGPRG--PPGPVGPSGK-DGANGIPGP---IGPPGPRGRSGETGPAGPPGNPGPP---- 1139

Query: 356  TGRGEGGGGGSRADVTA-GRARPRRRRWEPLRAQRSGARPG 395
               G  G  G   D++A     PR +  +PL+  R+    G
Sbjct: 1140 ---GPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAG 1177


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 112/482 (23%), Positives = 154/482 (31%), Gaps = 91/482 (18%)

Query: 23   PGGKRGTEIRAVGEQLESWRSWRK-------------DVAGCSSPTPIPEFGAAAPTKSA 69
            P G+  +E R+ G + E     R+             D+A      P P+ G       A
Sbjct: 1079 PRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLA 1138

Query: 70   LQVQVVPSSQA-VEFGQHPGRGLQDRTQPTRIIRG--------CTVTSPSRQSETQITPA 120
                  P S A   F    GR    R  P+R  RG        C   SP  +S     P 
Sbjct: 1139 PPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPP 1198

Query: 121  GGPAAFCDSTAESKRQLRVG-----AEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQ 175
             GP     S    K +L  G     A G   G   +G               +G RP R+
Sbjct: 1199 TGPLP--PSKEPLKEKLIPGPLSPVARGGSNGGSNVGM-------------EDGERPRRR 1243

Query: 176  RRTRRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHG-SP 234
            R  R         Q  P   RR     E A    EG PS      +      L++   +P
Sbjct: 1244 RHGRAQQ------QDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAP 1297

Query: 235  GTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRC 294
               +++   P L+N  +   ++    + E       SS F  ++ G              
Sbjct: 1298 APRRAAAKSPDLSNQNSDQANEEWETASE-------SSDFTSERRGDKE----------- 1339

Query: 295  LPSPPRSLVAPSESGSAGRRGG---------TNGVATPREKLGGKRGVGRKGQGTRLGAP 345
              +PP  L+ P   G+ G  GG         + G  + R K   KR    +  G      
Sbjct: 1340 --APPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNR 1397

Query: 346  HSLPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLP 405
               P      +G   GGGGG     T G  R  +R W   + +        P  PLP  P
Sbjct: 1398 RPGPGGKAGSSGSSSGGGGGGPGGRT-GPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPP 1456

Query: 406  PAA--------VCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGP 457
            P++        V H+   AG      +L    G+    GG    P   P  P    GP P
Sbjct: 1457 PSSSAVFRLDQVIHS-NPAGIQQALAQLSSRQGSVTAPGGH---PRHKPGLPQAPQGPSP 1512

Query: 458  LP 459
             P
Sbjct: 1513 RP 1514



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 80/323 (24%), Positives = 104/323 (32%), Gaps = 60/323 (18%)

Query: 179  RRPARALNSGQWSPGEGRRAALGLEEAGP----SLEGIPSSEWDTFSRDKRSLLS----- 229
            R+PAR + SG   P   RR +      GP    S  GIP  E     R    +       
Sbjct: 900  RKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPT 959

Query: 230  --SHGSPGTIQSSVDIPS--------LTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQL 279
                  P  ++   + P         +T    GG  +TPP       P  L   +  +++
Sbjct: 960  KVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPR-LRRDYSYERV 1018

Query: 280  GSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQG 339
            G          PT C         A    G  G  GG    A  RE    +   G  G+G
Sbjct: 1019 G----------PTSCRGRGRGEYFARGR-GFRGTYGGRGRGARSREFRSYREFRGDDGRG 1067

Query: 340  TRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRW----------------- 382
               G P+  PP P  RT       G    ++      P+RRR                  
Sbjct: 1068 GGTGGPNH-PPAPRGRTASETRSEGSEYEEI------PKRRRQRGSETGSETHESDLAPS 1120

Query: 383  -EPLRAQRSGARPGAP-APPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAA 440
             +     + G     P APP P  PP+    A A   A GGR+       +R  RGGG  
Sbjct: 1121 DKEAPTPKEGTLTQVPLAPPPPGAPPSP---APARFTARGGRVFTPRGVPSRRGRGGGRP 1177

Query: 441  VPTAAPPAPLPRWGPGPLPGPTG 463
             P   P    P     P   PTG
Sbjct: 1178 PPQVCPGWSPPAKSLAPKKPPTG 1200



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 81/344 (23%), Positives = 107/344 (31%), Gaps = 45/344 (13%)

Query: 159 GPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAAL---GLEEAGPSLEGIPSS 215
           GPQGP R+P    P+R  R   P  +    +     GR + L    L+E    L+     
Sbjct: 266 GPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFD-QLDQENDD 324

Query: 216 EWDTFSRD---KRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSS 272
            W     +      L  S    G            ++ +   ++ PP +         S 
Sbjct: 325 GWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSE 384

Query: 273 PFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRG 332
           P  PK   + +   P   P    P PP   + P   G AG  G                 
Sbjct: 385 PPTPKTAWAETSRPPETEPGPPAPKPP---LPPPHRGPAGNWGPP--------------- 426

Query: 333 VGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGA 392
               G     G P   PP P             S ++++    R RRRR E  R  +   
Sbjct: 427 ----GDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEER 482

Query: 393 RPGAPAPPLPCLPPAAVCHALAGAGAPGGRL--ELGLSPGTRLIRGGGAAVPTA--APPA 448
           R  A A  L  L            GAP  RL  E    P          AVP    APPA
Sbjct: 483 R-AACAEKLKRLDEKF--------GAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPA 533

Query: 449 PLPRWGPGPLPGPTGLFDLSVGVSAASSSLGSTELEKNMGSGGG 492
           P P   P P   P    + +    A S+          + SGGG
Sbjct: 534 PPPASAPTPETEPE---EPAQAPPAQSTPTPGVAAAPTLVSGGG 574


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 42/116 (36%), Positives = 46/116 (39%), Gaps = 6/116 (5%)

Query: 349 PPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAA 408
           PPPPP  + +     G   A    G A P      P     SGA PG+   P P  PPA 
Sbjct: 99  PPPPPQDSSKPVVAQGPGPAP-GVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAV 157

Query: 409 VCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAP-PAPLPRWGPGPLPGPTG 463
                A  GAP         P T    GG    P A P P P P+ GPGP  GP G
Sbjct: 158 TS---APPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP-GGPKG 209



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 43/155 (27%), Positives = 54/155 (34%), Gaps = 25/155 (16%)

Query: 324 REKLGGKRGVGRKGQGTRLGAPHSLPPPPP---FRTGRGE--GGGGGSRADVTAGRARPR 378
           R + GG  G  R+G G   G  H    PPP       RG    G G S          P 
Sbjct: 7   RSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPH 66

Query: 379 RRRWEPLRAQRSGARPGAPAPP---------LPCLPPAAVCHALAGAGAPGGRLELGLSP 429
           +++ +P   Q    +P    PP          P  PP      +   G        G +P
Sbjct: 67  QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP-------GPAP 119

Query: 430 GTRLIRGGGAAVPTAAPP---APLPRWGPGPLPGP 461
           G        ++ P A PP   AP P  GPGP P P
Sbjct: 120 GVGSAPPASSSAPPATPPTSGAP-PGSGPGPTPTP 153



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 51/206 (24%), Positives = 67/206 (32%), Gaps = 41/206 (19%)

Query: 160 PQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDT 219
           PQ P        P   ++ + P    +S +    +G   A G+  A P+    P +   T
Sbjct: 79  PQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPT 138

Query: 220 FSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQL 279
                 S       PG   +    P++T+   G    TPP S           P  P Q 
Sbjct: 139 SGAPPGS------GPGPTPTPP--PAVTSAPPGAPPPTPPSS---------GVPTTPPQA 181

Query: 280 GSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRK-GQ 338
           G               P PP ++  P      G      G   P+   GGK   G K G 
Sbjct: 182 GGP-------------PPPPAAVPGPGPGPKQGP-----GPGGPK---GGKMPGGPKPGG 220

Query: 339 GTRLGAPHSLPPPPPFRTGRGEGGGG 364
           G  L  P   P PP    G GE  GG
Sbjct: 221 GPGLSTPGGHPKPP--HRGGGEPRGG 244


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 70/242 (28%), Positives = 88/242 (36%), Gaps = 59/242 (24%)

Query: 259 PFSQEVD---DPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRS--LVAPSESGSAGR 313
           PFS        P A   P  P  L +  L++P        PSPP S  L AP    + G 
Sbjct: 543 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVP--------PSPPASPTLQAPRRPPTPGP 594

Query: 314 RGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAG 373
               +G   PR  L    G                PPPPP R+      G       ++ 
Sbjct: 595 DTSVSG---PRLTLALAPG----------------PPPPPSRSPSSTLSGPDLAGHSSSA 635

Query: 374 RARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRL 433
            + P     E LR   SG   GA A P P    AA CH  A +  P   L    +PG  L
Sbjct: 636 TSTP-----EELRGYDSGPEGGAAASPPPDAELAA-CHPAAWSRGPAPPLAFRGAPGAPL 689

Query: 434 ----IRGGGAA----------VPTAAPPAPLPRWGPGPLPGPTGLFDLSVGVSAASSSLG 479
                 G G+A           P +A PAP     PGP PG +G      G +AA +  G
Sbjct: 690 PWPPATGPGSADGLCTIYETEGPESATPAP-GALDPGPSPGTSG------GKAAAGAGAG 742

Query: 480 ST 481
           ++
Sbjct: 743 AS 744



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 7/55 (12%)

Query: 394 PGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPA 448
           PG+P PP P  P  A    L  AGA G +     + G      GGA +P +AP A
Sbjct: 30  PGSPRPPPPVTP--AALRVLGAAGAVGRKPLAERAGGI-----GGATIPESAPRA 77


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 70/242 (28%), Positives = 88/242 (36%), Gaps = 59/242 (24%)

Query: 259  PFSQEVD---DPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRS--LVAPSESGSAGR 313
            PFS        P A   P  P  L +  L++P        PSPP S  L AP    + G 
Sbjct: 812  PFSPSASLPMSPLATPPPQAPPVLAAPLLQVP--------PSPPASPTLQAPRRPPTPGP 863

Query: 314  RGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAG 373
                +G   PR  L    G                PPPPP R+      G       ++ 
Sbjct: 864  DTSVSG---PRLTLALAPG----------------PPPPPSRSPSSTLSGPDLAGHSSSA 904

Query: 374  RARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRL 433
             + P     E LR   SG   GA A P P    AA CH  A +  P   L    +PG  L
Sbjct: 905  TSTP-----EELRGYDSGPEGGAAASPPPDAELAA-CHPAAWSRGPAPPLAFRGAPGAPL 958

Query: 434  ----IRGGGAA----------VPTAAPPAPLPRWGPGPLPGPTGLFDLSVGVSAASSSLG 479
                  G G+A           P +A PAP     PGP PG +G      G +AA +  G
Sbjct: 959  PWPPATGPGSADGLCTIYETEGPESATPAP-GALDPGPSPGTSG------GKAAAGAGAG 1011

Query: 480  ST 481
            ++
Sbjct: 1012 AS 1013



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 7/55 (12%)

Query: 394 PGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPA 448
           PG+P PP P  P  A    L  AGA G +     + G      GGA +P +AP A
Sbjct: 30  PGSPRPPPPVTP--AALRVLGAAGAVGRKPLAERAGGI-----GGATIPESAPRA 77



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 101/454 (22%), Positives = 152/454 (33%), Gaps = 79/454 (17%)

Query: 45  RKDVAGCSSPTPIPEFGA---AAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRII 101
           R+D +G +  TP P       AA T+  L  +  PS++     + P + +   ++ +   
Sbjct: 161 RRDTSGPTPGTPSPAMARRSRAAGTEVGLP-RPAPSARPRPPTEGPRKSVSSASEHS--- 216

Query: 102 RGCTVTSPSRQSETQITPAGG---PAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVN 158
                T PS  +  + +  GG   PA+   S + S   L   A     GP A G  R   
Sbjct: 217 ----TTEPSPAARRRPSAGGGLQRPAS--RSLSSSATPLSSPARS---GPSARGTPRAPA 267

Query: 159 GPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLEEAGPS-LEGIPSSEW 217
            P  P   P G +  R  +   P +       +P  G  ++  L    PS  +  P    
Sbjct: 268 HPSQPK--PKGLQALRPPQVTPPRKDA-----APALGPLSSSPLATPSPSGTKARPVPPP 320

Query: 218 DTFSRDKRSLLS--------------SHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQE 263
           D  +    + L               S  +P ++Q+    P+   + A     TPP    
Sbjct: 321 DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380

Query: 264 --------VDDPHALSSPFF---PKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAG 312
                   +  PH+L+SP     P  L   SL+    L +  L +    L        A 
Sbjct: 381 PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS 440

Query: 313 RRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTA 372
               +   +TP +                L AP SLP  PP +T         S +   +
Sbjct: 441 LTSPSRPASTPPDS-------------PPLQAPLSLPASPPLQT---------SLSPAVS 478

Query: 373 GRARPRRRRWEPLRAQRSGA--RPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPG 430
             + P      PL+A  S A   P AP   L  +PP     +LA          L   P 
Sbjct: 479 PLSSP--LTIHPLQALSSLASHSPQAPLSSL-IMPPLETQSSLAPPSLQTPPASLTTPPL 535

Query: 431 TRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGL 464
             L       + TA+ P   P     P P P  L
Sbjct: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 70/242 (28%), Positives = 88/242 (36%), Gaps = 59/242 (24%)

Query: 259 PFSQEVD---DPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRS--LVAPSESGSAGR 313
           PFS        P A   P  P  L +  L++P        PSPP S  L AP    + G 
Sbjct: 504 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVP--------PSPPASPTLQAPRRPPTPGP 555

Query: 314 RGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAG 373
               +G   PR  L    G                PPPPP R+      G       ++ 
Sbjct: 556 DTSVSG---PRLTLALAPG----------------PPPPPSRSPSSTLSGPDLAGHSSSA 596

Query: 374 RARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRL 433
            + P     E LR   SG   GA A P P    AA CH  A +  P   L    +PG  L
Sbjct: 597 TSTP-----EELRGYDSGPEGGAAASPPPDAELAA-CHPAAWSRGPAPPLAFRGAPGAPL 650

Query: 434 ----IRGGGAA----------VPTAAPPAPLPRWGPGPLPGPTGLFDLSVGVSAASSSLG 479
                 G G+A           P +A PAP     PGP PG +G      G +AA +  G
Sbjct: 651 PWPPATGPGSADGLCTIYETEGPESATPAP-GALDPGPSPGTSG------GKAAAGAGAG 703

Query: 480 ST 481
           ++
Sbjct: 704 AS 705



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 34/128 (26%), Positives = 43/128 (33%), Gaps = 36/128 (28%)

Query: 394 PGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPA----- 448
           PG+P PP P  P  A    L  AGA G +     + G      GGA +P +AP A     
Sbjct: 30  PGSPRPPPPVTP--AALRVLGAAGAVGRKPLAERAGGI-----GGATIPESAPRAGPTRT 82

Query: 449 -------------PLPRWGPGPL-----------PGPTGLFDLSVGVSAASSSLGSTELE 484
                        P     PGP+           PGP G   L +      +   +TE  
Sbjct: 83  SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 142

Query: 485 KNMGSGGG 492
           K      G
Sbjct: 143 KRSALSAG 150



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 48/176 (27%), Positives = 56/176 (31%), Gaps = 36/176 (20%)

Query: 288 ARLPTRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHS 347
           AR P    P PP S   P     A  R            LG    VGRK    R G    
Sbjct: 19  ARAPGLLTPRPPGSPRPPPPVTPAALR-----------VLGAAGAVGRKPLAERAG---- 63

Query: 348 LPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPA 407
                         G GG+    +A RA P R    P   +   A P     P P   P 
Sbjct: 64  --------------GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPG 109

Query: 408 AVCHALAGAGAPG--GRLELGLSPGTRLIRGGGAAVP-TAAPPAPLPRWGPGPLPG 460
                 +G   PG  G+  L +S    + RG     P  +A  A   R   GP PG
Sbjct: 110 RA----SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 161


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 95/349 (27%), Positives = 119/349 (34%), Gaps = 51/349 (14%)

Query: 140 GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAA 199
           G  G  G P + G G    GP GP  +P    P       +P R    G  +PG G +  
Sbjct: 190 GDPGLPGLPGSWGAG----GPAGPTGYPG--EPGLVGPPGQPGRPGLKG--NPGVGVKGQ 241

Query: 200 LGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGT--IQSSVDIPSL------TNTCA 251
           +G     P   G   S   T   +        G  G   I   V +P        +   A
Sbjct: 242 MG----DPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGA 297

Query: 252 GGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAP-SESGS 310
            G+   P F     DP +  SP FP   G L L     L           L+ P  + G+
Sbjct: 298 KGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGL---------FGLIGPKGDPGN 348

Query: 311 AGRRGGTNGVATPREKLGGKRG----VGRKGQGTRLGAPHSLPPPPPFRTGR-GE----- 360
            G  G    + TP   L G  G     GR G+   +G     PP PP   GR GE     
Sbjct: 349 RGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVG-----PPGPPGLLGRPGEACAGM 403

Query: 361 -GGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAP----APPLPCLPPAAVCHALAG 415
            G  G        G          P  A     +PG+P    AP L  LP ++V +   G
Sbjct: 404 IGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVG 463

Query: 416 AGAPGGRLELGLSPGTRLIRG-GGAAVPTAAPPAPLPRWGPGPLPGPTG 463
              P G       PG R  +G  G     A  P P+   GP  LPG  G
Sbjct: 464 NPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQG 512



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 93/348 (26%), Positives = 117/348 (33%), Gaps = 67/348 (19%)

Query: 140 GAEGKGGGPQALGRGRR----VNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE- 194
           G  G  G P  LGR       + GP GP  +P    P        P R  ++    PG+ 
Sbjct: 382 GDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPG--LPGLPGEAGIPGRPDSA----PGKP 435

Query: 195 GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGT--IQSSVDIPSLTNTCAG 252
           G+  + GL  A P L+G+P S           +  S G+PG   I+  V  P       G
Sbjct: 436 GKPGSPGLPGA-PGLQGLPGSS---------VIYCSVGNPGPQGIKGKVGPPGGRGP-KG 484

Query: 253 GKDKTPPFSQEVDDPHALSSPFFPKQLGSLS-LELPARLPTRCLPSPPRSLVAP------ 305
            K      + E         P  P + GS   L LP  L T+  P PP +   P      
Sbjct: 485 EKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKH 544

Query: 306 SESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTG-RGEGGGG 364
             SG  G +G    +   R K       G KG+    G     PP  P + G  G  G  
Sbjct: 545 GASGPPGNKGAKGDMVVSRVK-------GHKGERGPDG-----PPGFPGQPGSHGRDGHA 592

Query: 365 GSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAV----CHALAGAGAPG 420
           G + D                      A PG    P P  PP          L   G PG
Sbjct: 593 GEKGDPGP-------------PGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPG 639

Query: 421 GRLELGLSPGTRLIRG----GGAAVPTAAPPAPLP-RWGPGPLPGPTG 463
            R   G+ PG   +RG     G    T +     P R GP    GP G
Sbjct: 640 ERGHPGV-PGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPG 686



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 68/246 (27%), Positives = 79/246 (32%), Gaps = 60/246 (24%)

Query: 251 AGGK-DKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESG 309
           AG K D  PP   E   P       FP  LG      P   P    P PP     P   G
Sbjct: 592 AGEKGDPGPPGDHEDATPGGKG---FPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPG 648

Query: 310 SAGRRG-------------------------GTNGVATPREKLGGKRGVGRKGQGTRLGA 344
             G RG                         G +G   P+   G +   G  G     G 
Sbjct: 649 HPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGR 708

Query: 345 PHS-----LPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAP 399
           P +     +P PP FR   G+ G GG +     G   P      P     +G + G P  
Sbjct: 709 PGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGP------PGSPGVNGQK-GIPGD 761

Query: 400 PLPCLPPAAVCHALAGAGAPGGRLELGLS--PGTRLIRGGGAAVPTAAPPAPLPRWGPGP 457
           P           A    G PG R   GLS  PG +  R G    P A  PA +P  G   
Sbjct: 762 P-----------AFGHLGPPGKR---GLSGVPGIKGPR-GDPGCPGAEGPAGIP--GFLG 804

Query: 458 LPGPTG 463
           L GP G
Sbjct: 805 LKGPKG 810



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 84/338 (24%), Positives = 103/338 (30%), Gaps = 72/338 (21%)

Query: 140  GAEGKGGGPQALGR-----GRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSG----QW 190
            G +G+ G P   G       + + G QGP   P   RP     +  P    + G    + 
Sbjct: 1085 GPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPG--RPGPPGSSGPPGCPGDHGMPGLRG 1142

Query: 191  SPGE-GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNT 249
             PGE G     GL+   P + G P  +  + S     L    G  GT  +S     L + 
Sbjct: 1143 QPGEMGDPGPRGLQ-GDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGAS----GLHDV 1197

Query: 250  CAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESG 309
               G    P    E  DP            GS  +  P     +  P PP S   P  +G
Sbjct: 1198 GPPGPVGIPGLKGERGDP------------GSPGISPPGPRGKKGPPGPPGSSGPPGPAG 1245

Query: 310  SAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRAD 369
            + GR      +  P                   G P    PP P    RG  G  G    
Sbjct: 1246 ATGR--APKDIPDP-------------------GPPGDQGPPGP-DGPRGAPGPPGLPGS 1283

Query: 370  VTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPA----AVCHALAGAGAPGGRLEL 425
            V   R  P                PG P PP P  PP       C    G   P G    
Sbjct: 1284 VDLLRGEP-----------GDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVG---- 1328

Query: 426  GLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
               PG +   G          P P  R GP  LPGP G
Sbjct: 1329 --FPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRG 1364



 Score = 36.2 bits (82), Expect = 0.070
 Identities = 55/190 (28%), Positives = 63/190 (33%), Gaps = 36/190 (18%)

Query: 304 APSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEG 361
           AP  SGS G +G  GT G A      G +  +G  G G   G+    PP PP     G  
Sbjct: 696 APGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPP--GSPGVN 753

Query: 362 GGGGSRADVTAGRARPRRRRWEPLRAQRSGAR-----PGAPAPP-LPCL----------- 404
           G  G   D   G   P  +R         G R     PGA  P  +P             
Sbjct: 754 GQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREG 813

Query: 405 ---------PPAAVCHALAGAGAPGGRLELGLS--PGTRLIRGGGAAVPTAAPPAPLPRW 453
                    PP   C      GAPG   + GL   PG+    GG        PP P    
Sbjct: 814 HAGFPGVPGPPGHSCER----GAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMK 869

Query: 454 GPGPLPGPTG 463
           G   LPG  G
Sbjct: 870 GLPGLPGRPG 879


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 90/343 (26%), Positives = 110/343 (32%), Gaps = 58/343 (16%)

Query: 140  GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAA 199
            G +G  G P   G    + GP G    P       Q R   P      G     +G R  
Sbjct: 1091 GDKGDAGPPGQPG----IRGPAGHPGPPGA--DGAQGRRGPPGLFGQKGD----DGVRGF 1140

Query: 200  LGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPP 259
            +G+    P L+G+P    +         +  HG+PG        P+       G + TP 
Sbjct: 1141 VGVI-GPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGP--RGPQGPT-------GSEGTPG 1190

Query: 260  FSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRG--GT 317
                V  P A+         G               P PP +   P   G  G +G  G 
Sbjct: 1191 LPGGVGQPGAVGEKGERGDAGD--------------PGPPGAPGIPGPKGDIGEKGDSGP 1236

Query: 318  NGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPP-----------PPFRTGRGE-GGGGG 365
            +G A P  K G     G KG     G P  L PP           P  +   G+ GG G 
Sbjct: 1237 SGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGP 1296

Query: 366  SRADVTAGRARPRRRRWEPLRAQRSG--ARPGAPAPPLPCLPPAAVCHALAGAGAPGGRL 423
              A    G   P  +R       R G     GA   P P  PP        GA  P GR+
Sbjct: 1297 PGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRT--GPMGARGPPGRV 1354

Query: 424  ---ELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
                L   PG     G   A     PP PL   GP  LPG  G
Sbjct: 1355 GPEGLRGIPGPVGEPGLLGAPGQMGPPGPL---GPSGLPGLKG 1394



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 56/191 (29%), Positives = 68/191 (35%), Gaps = 44/191 (23%)

Query: 280  GSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRG-----GTNGVATPREKLGGKRGVG 334
            G L  E PA L  R  P P      P  +G  G +G     G NG    R  LG   G+G
Sbjct: 965  GPLGKEGPAGL--RGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIG 1022

Query: 335  RKGQGTRLGAPHSLPPPPPFRTG-RGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGAR 393
              GQ    G     P  P  + G RGE G  G                           +
Sbjct: 1023 LPGQSGSEG-----PVGPAGKKGSRGERGPPGPT------------------------GK 1053

Query: 394  PGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGG-GAAVPTAAPPAPLPR 452
             G P P  P  PP A       +G  G + ++G +PG +  +G  G A P   P    P 
Sbjct: 1054 DGIPGPLGPLGPPGAA----GPSGEEGDKGDVG-APGHKGSKGDKGDAGPPGQPGIRGPA 1108

Query: 453  WGPGPLPGPTG 463
              PGP PG  G
Sbjct: 1109 GHPGP-PGADG 1118



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 103/396 (26%), Positives = 123/396 (31%), Gaps = 83/396 (20%)

Query: 138 RVGAEGKGGGPQALGRGRRVNGPQGPD--RWPNGFRPARQRRTRRPA------------- 182
           R G  G  G P   G      GPQGP   + P+G  P R  +  RP              
Sbjct: 489 RPGPVGLPGHPGLKGE-EGAEGPQGPRGLQGPHG-PPGRVGKMGRPGADGARGLPGDTGP 546

Query: 183 ---RALNSGQWSPGE-GRRAALG-LEEAGP-------SLEGIPSSEWDTFSRDKRSLLSS 230
              R  +     PGE G+R   G + + GP         EG P           R LL  
Sbjct: 547 KGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGP 606

Query: 231 HGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARL 290
            GSPG        P +T     G D  P     V  P     P      GS  L  P  L
Sbjct: 607 RGSPGPTGR----PGVT-----GIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGL 657

Query: 291 -------------PTRCLPSPPRSLVAPSESGSAGRRG--------GTNGVATPREKLG- 328
                            LP     L  P   G  G +G        G  G   PR   G 
Sbjct: 658 IGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGT 717

Query: 329 -GKRGV-GRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADV----TAGRARPRRRRW 382
            G RG+ G KG+    G P         +  +G+ G  G R +       G+A       
Sbjct: 718 SGNRGLQGEKGEKGEDGFP-GFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEG 776

Query: 383 EPLRAQRSG--------ARPGAPAP------PLPCLPPAAVCHALAGAGAPGGRLELGLS 428
            P  A   G          PG P P      P P L P          G PG   E G  
Sbjct: 777 PPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGP-LGPIGEKGKSGKTGQPGLEGERG-P 834

Query: 429 PGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGL 464
           PG+R  RG   A     P   + + G   +PG  GL
Sbjct: 835 PGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGL 870



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 61/189 (32%), Positives = 71/189 (37%), Gaps = 64/189 (33%)

Query: 309 GSAGRRG--GTNGVATPREKLG--GKRGV-GRKGQGTRLGAPHSLPPP--PPFRTGR-GE 360
           GS G RG  G  G   P+  +G  G  G+ G KG     G P   P P  PP   G+ G 
Sbjct: 836 GSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPP-GFPGPKGPPGHQGKDGR 894

Query: 361 GGGGGSRADV----------TAGRARPRRRRWE--PLRAQRSGARPGAPAPPLPCLPPAA 408
            G  G R ++           AG   P+ +  E  PL     G R G P PP        
Sbjct: 895 PGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPL-----GER-GPPGPP-------- 940

Query: 409 VCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPL-------------PRWGP 455
                   G PG   E GL PG   + G   A     PP PL             P+ GP
Sbjct: 941 --------GPPG---EQGL-PG---LEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGP 985

Query: 456 GPLPGPTGL 464
           G  PGPTGL
Sbjct: 986 GD-PGPTGL 993


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
           [Homo sapiens]
          Length = 3969

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 38/122 (31%), Positives = 50/122 (40%), Gaps = 10/122 (8%)

Query: 353 PFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHA 412
           P R G   GGGGG R  +     +       P      G  PGAP  P P +  AA    
Sbjct: 10  PARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSP-PAVAAAAAAAG 68

Query: 413 LAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLFDLSVGVS 472
            +GAG PGG      +  +       ++   ++ PA L R GPG        FD ++ VS
Sbjct: 69  SSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPA-LLRVGPG--------FDAALQVS 119

Query: 473 AA 474
           AA
Sbjct: 120 AA 121


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 85/347 (24%), Positives = 107/347 (30%), Gaps = 55/347 (15%)

Query: 122  GPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRP 181
            GPA    S  E   +  +G  G+ G     G     NGP GP        P  Q     P
Sbjct: 1126 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE----NGPPGP--------PGLQGPVGAP 1173

Query: 182  ARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSV 241
              A   G+  P  G++   G ++      G P             L    G PG    + 
Sbjct: 1174 GIAGGDGEPGP-RGQQGMFG-QKGDEGARGFPGPPGPI------GLQGLPGPPGEKGENG 1225

Query: 242  DIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPK-QLGSLSLELPARLPTRC-LPSPP 299
            D+  +           PP  +    P+    P  P   +GS+        P     P PP
Sbjct: 1226 DVGPMG-------PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP 1278

Query: 300  RSLVAPSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTG 357
                     G  G +G  G  G A P    G     G KG    +G P    PP      
Sbjct: 1279 GEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPA 1338

Query: 358  RGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAG 417
              +G GG    D   G+  P     E           G P PP    PP A       AG
Sbjct: 1339 GQDGVGGDKGEDGDPGQPGPPGPSGEA----------GPPGPPGKRGPPGA-------AG 1381

Query: 418  APGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGL 464
            A G + E G        +G   A        P+   GP   PGP GL
Sbjct: 1382 AEGRQGEKGA-------KGEAGAEGPPGKTGPVGPQGPAGKPGPEGL 1421



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 91/345 (26%), Positives = 115/345 (33%), Gaps = 80/345 (23%)

Query: 140  GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-GRRA 198
            G +GK G P   G    V GPQGP        P  +R    P          PGE G   
Sbjct: 967  GFQGKTGPPGPGG----VVGPQGPTGETG---PIGERGHPGPPGP-------PGEQGLPG 1012

Query: 199  ALGLEEA--GPSLEGIPSSEWDTFSRD---KRSLLSSHGSPGTIQSSVDIPSLTNTCAGG 253
            A G E A   P  +GI   +     R    +R L  + G+PG                GG
Sbjct: 1013 AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGL--------------KGG 1058

Query: 254  KDKTPPFSQEVDDPHALSSPFFPKQLGSLS-LELPARLPTRCLPSPPRSLVAPSESGSAG 312
            +    P       P  + SP      G+   + LP R   +  P P     AP E G  G
Sbjct: 1059 EGPQGP-------PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1111

Query: 313  RRG-----------GTNGVATPREKLGGKRGVGRKGQ-GTRLGAPHSLPPPPPFRTGRGE 360
              G           G  G A    + G K  +G  GQ G++     + PP PP   G   
Sbjct: 1112 PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1171

Query: 361  GGGGGSRADVTAGRARPRRRRWEPLRAQRS--GARPGAPAPPLPCLPPAAVCHALAGAGA 418
              G      +  G   P  R  + +  Q+   GAR G P PP P          +   G 
Sbjct: 1172 APG------IAGGDGEPGPRGQQGMFGQKGDEGAR-GFPGPPGP----------IGLQGL 1214

Query: 419  PGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
            PG        PG +   G    +    PP P    GP    GP G
Sbjct: 1215 PG-------PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQG 1252



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 82/332 (24%), Positives = 98/332 (29%), Gaps = 45/332 (13%)

Query: 145  GGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLEE 204
            G GP      R   GPQGP  +P    P        P +    G   PG+        + 
Sbjct: 920  GDGPPGPPGERGPQGPQGPVGFPGPKGPPGP-----PGKDGLPGH--PGQRGETGFQGKT 972

Query: 205  AGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEV 264
              P   G+   +  T            G PG       +P          D  P      
Sbjct: 973  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGP-PGEQGLPGAAGKEGAKGDPGPQGISGK 1031

Query: 265  DDPHALSSPFFPKQLGSLSLE-LPARLPTRCLPSPPRSLVAPSESGSAGRRG-----GTN 318
            D P  L    FP + G    +  P          PP  + +P E GSAG  G     G  
Sbjct: 1032 DGPAGLRG--FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1089

Query: 319  GVATPREKLGGKRGVGRKGQGTRLG-----APHSLPPPPPFRTGRGEGGGGGSRADVTAG 373
            G   P    G K   G KG     G      P  LP P       GE G  G        
Sbjct: 1090 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG----- 1144

Query: 374  RARPRRRRWEPLRAQRSG--ARPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGT 431
                     EP +    G     G P PP     P        G G PG R + G+    
Sbjct: 1145 ---------EPGQKGSKGDKGENGPPGPP-GLQGPVGAPGIAGGDGEPGPRGQQGMFGQ- 1193

Query: 432  RLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
               +G   A     PP P+   G   LPGP G
Sbjct: 1194 ---KGDEGARGFPGPPGPIGLQG---LPGPPG 1219



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 88/363 (24%), Positives = 119/363 (32%), Gaps = 93/363 (25%)

Query: 119 PAGGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRT 178
           P GGP +              GA+G+ G P   G  R V GP GP   P           
Sbjct: 554 PVGGPGSS-------------GAKGESGDPGPQGP-RGVQGPPGPTGKPG---------- 589

Query: 179 RRPARALNSGQWSPGE-GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTI 237
           +R     + G+  PGE G +   G +       G+P    D   R +R      G PG  
Sbjct: 590 KRGRPGADGGRGMPGEPGAKGDRGFD-------GLPGLPGDKGHRGERGPQGPPGPPG-- 640

Query: 238 QSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPS 297
                     +    G+D                      ++G      P  LP     +
Sbjct: 641 ----------DDGMRGEDG---------------------EIG------PRGLPGE---A 660

Query: 298 PPRSLVAP-SESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPF 354
            PR L+ P    G+ G+ G  G +G   P+  +G +   G  GQ    G P  LP P   
Sbjct: 661 GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPG-PQGLPGPQGP 719

Query: 355 RTGRGEGG--GGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAV--- 409
               GE G  G    A +      P     E    ++    P  P  P+    P  V   
Sbjct: 720 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 779

Query: 410 --CHALAGA-------GAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPG 460
                L G+       G PG + ++GL  G R   G         P  P  R GP   PG
Sbjct: 780 DGVRGLKGSKGEKGEDGFPGFKGDMGLK-GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 838

Query: 461 PTG 463
           P+G
Sbjct: 839 PSG 841



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 85/337 (25%), Positives = 103/337 (30%), Gaps = 81/337 (24%)

Query: 140 GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFR--PARQRRTRRPARALNSGQWSPGE-GR 196
           G +G+ G P  +  G  V GP GP   P G    P  Q  T  P          PG+ G 
Sbjct: 435 GEKGQKGEPAVVEPGMLVEGPPGP-AGPAGIMGPPGLQGPTGPPG--------DPGDRGP 485

Query: 197 RAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDK 256
               GL    P  +G+P                  G PGT+        L     G   K
Sbjct: 486 PGRPGL----PGADGLP------------------GPPGTMLM------LPFRYGGDGSK 517

Query: 257 TPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSP------PRSLVAPSESGS 310
            P  S +     A+                 AR+  R  P P      P  +  P  SG+
Sbjct: 518 GPTISAQEAQAQAILQQ--------------ARIALRGPPGPMGLTGRPGPVGGPGSSGA 563

Query: 311 AGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAP--HSLPPPPPFRTGRGEGGGGGSRA 368
            G  G   G   PR   G     G+ G+  R GA     +P  P  +  RG  G  G   
Sbjct: 564 KGESGDP-GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPG 622

Query: 369 DVTAGRARPRRRRWEPLRAQRSGAR--PGAPAPPLPCLPPAAVCHALAGAGAPGGRLELG 426
           D   G    R  +  P      G R   G   P             L G   P G L   
Sbjct: 623 D--KGHRGERGPQGPPGPPGDDGMRGEDGEIGP-----------RGLPGEAGPRGLLGPR 669

Query: 427 LSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
            +PG     G         PP P    GP   PGP G
Sbjct: 670 GTPGAP---GQPGMAGVDGPPGPKGNMGPQGEPGPPG 703



 Score = 36.6 bits (83), Expect = 0.053
 Identities = 88/344 (25%), Positives = 109/344 (31%), Gaps = 67/344 (19%)

Query: 139  VGAEGKGG--GPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-- 194
            VG  G  G  GP+        +GPQGP           ++    P  A N G   PGE  
Sbjct: 1227 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG--EPGEAGNPGP--PGEAG 1282

Query: 195  -----GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNT 249
                 G R   G  EAGP     P +     ++         G+PG +    D       
Sbjct: 1283 VGGPKGERGEKG--EAGP-----PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1335

Query: 250  CAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESG 309
               G+D       E  DP     P    + G               P PP     P  +G
Sbjct: 1336 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP--------------PGPPGKRGPPGAAG 1381

Query: 310  SAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRAD 369
            + GR+G         EK       G KG+    G P    P  P      +G  G    +
Sbjct: 1382 AEGRQG---------EK-------GAKGEAGAEGPPGKTGPVGP------QGPAGKPGPE 1419

Query: 370  VTAGRARPRRRRWEPLRAQRSGARPGAPAPP-LPCLPPAAVCHALAG-------AGAPGG 421
               G   P   +  P  A + G  PG   PP LP L          G        G PG 
Sbjct: 1420 GLRGIPGPVGEQGLPGAAGQDGP-PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1478

Query: 422  RLELGLS--PGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
            + E G    PGT+   G         P  PL   GP  LPGP G
Sbjct: 1479 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1522


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 85/347 (24%), Positives = 107/347 (30%), Gaps = 55/347 (15%)

Query: 122  GPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRP 181
            GPA    S  E   +  +G  G+ G     G     NGP GP        P  Q     P
Sbjct: 1075 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE----NGPPGP--------PGLQGPVGAP 1122

Query: 182  ARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSV 241
              A   G+  P  G++   G ++      G P             L    G PG    + 
Sbjct: 1123 GIAGGDGEPGP-RGQQGMFG-QKGDEGARGFPGPPGPI------GLQGLPGPPGEKGENG 1174

Query: 242  DIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPK-QLGSLSLELPARLPTRC-LPSPP 299
            D+  +           PP  +    P+    P  P   +GS+        P     P PP
Sbjct: 1175 DVGPMG-------PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP 1227

Query: 300  RSLVAPSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTG 357
                     G  G +G  G  G A P    G     G KG    +G P    PP      
Sbjct: 1228 GEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPA 1287

Query: 358  RGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAG 417
              +G GG    D   G+  P     E           G P PP    PP A       AG
Sbjct: 1288 GQDGVGGDKGEDGDPGQPGPPGPSGEA----------GPPGPPGKRGPPGA-------AG 1330

Query: 418  APGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGL 464
            A G + E G        +G   A        P+   GP   PGP GL
Sbjct: 1331 AEGRQGEKGA-------KGEAGAEGPPGKTGPVGPQGPAGKPGPEGL 1370



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 91/345 (26%), Positives = 115/345 (33%), Gaps = 80/345 (23%)

Query: 140  GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-GRRA 198
            G +GK G P   G    V GPQGP        P  +R    P          PGE G   
Sbjct: 916  GFQGKTGPPGPGG----VVGPQGPTGETG---PIGERGHPGPPGP-------PGEQGLPG 961

Query: 199  ALGLEEA--GPSLEGIPSSEWDTFSRD---KRSLLSSHGSPGTIQSSVDIPSLTNTCAGG 253
            A G E A   P  +GI   +     R    +R L  + G+PG                GG
Sbjct: 962  AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGL--------------KGG 1007

Query: 254  KDKTPPFSQEVDDPHALSSPFFPKQLGSLS-LELPARLPTRCLPSPPRSLVAPSESGSAG 312
            +    P       P  + SP      G+   + LP R   +  P P     AP E G  G
Sbjct: 1008 EGPQGP-------PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1060

Query: 313  RRG-----------GTNGVATPREKLGGKRGVGRKGQ-GTRLGAPHSLPPPPPFRTGRGE 360
              G           G  G A    + G K  +G  GQ G++     + PP PP   G   
Sbjct: 1061 PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1120

Query: 361  GGGGGSRADVTAGRARPRRRRWEPLRAQRS--GARPGAPAPPLPCLPPAAVCHALAGAGA 418
              G      +  G   P  R  + +  Q+   GAR G P PP P          +   G 
Sbjct: 1121 APG------IAGGDGEPGPRGQQGMFGQKGDEGAR-GFPGPPGP----------IGLQGL 1163

Query: 419  PGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
            PG        PG +   G    +    PP P    GP    GP G
Sbjct: 1164 PG-------PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQG 1201



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 82/332 (24%), Positives = 98/332 (29%), Gaps = 45/332 (13%)

Query: 145  GGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLEE 204
            G GP      R   GPQGP  +P    P        P +    G   PG+        + 
Sbjct: 869  GDGPPGPPGERGPQGPQGPVGFPGPKGPPGP-----PGKDGLPGH--PGQRGETGFQGKT 921

Query: 205  AGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEV 264
              P   G+   +  T            G PG       +P          D  P      
Sbjct: 922  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGP-PGEQGLPGAAGKEGAKGDPGPQGISGK 980

Query: 265  DDPHALSSPFFPKQLGSLSLE-LPARLPTRCLPSPPRSLVAPSESGSAGRRG-----GTN 318
            D P  L    FP + G    +  P          PP  + +P E GSAG  G     G  
Sbjct: 981  DGPAGLRG--FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1038

Query: 319  GVATPREKLGGKRGVGRKGQGTRLG-----APHSLPPPPPFRTGRGEGGGGGSRADVTAG 373
            G   P    G K   G KG     G      P  LP P       GE G  G        
Sbjct: 1039 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG----- 1093

Query: 374  RARPRRRRWEPLRAQRSG--ARPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGT 431
                     EP +    G     G P PP     P        G G PG R + G+    
Sbjct: 1094 ---------EPGQKGSKGDKGENGPPGPP-GLQGPVGAPGIAGGDGEPGPRGQQGMFGQ- 1142

Query: 432  RLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
               +G   A     PP P+   G   LPGP G
Sbjct: 1143 ---KGDEGARGFPGPPGPIGLQG---LPGPPG 1168



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 88/363 (24%), Positives = 119/363 (32%), Gaps = 93/363 (25%)

Query: 119 PAGGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRT 178
           P GGP +              GA+G+ G P   G  R V GP GP   P           
Sbjct: 503 PVGGPGSS-------------GAKGESGDPGPQGP-RGVQGPPGPTGKPG---------- 538

Query: 179 RRPARALNSGQWSPGE-GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTI 237
           +R     + G+  PGE G +   G +       G+P    D   R +R      G PG  
Sbjct: 539 KRGRPGADGGRGMPGEPGAKGDRGFD-------GLPGLPGDKGHRGERGPQGPPGPPG-- 589

Query: 238 QSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPS 297
                     +    G+D                      ++G      P  LP     +
Sbjct: 590 ----------DDGMRGEDG---------------------EIG------PRGLPGE---A 609

Query: 298 PPRSLVAP-SESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPF 354
            PR L+ P    G+ G+ G  G +G   P+  +G +   G  GQ    G P  LP P   
Sbjct: 610 GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPG-PQGLPGPQGP 668

Query: 355 RTGRGEGG--GGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAV--- 409
               GE G  G    A +      P     E    ++    P  P  P+    P  V   
Sbjct: 669 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 728

Query: 410 --CHALAGA-------GAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPG 460
                L G+       G PG + ++GL  G R   G         P  P  R GP   PG
Sbjct: 729 DGVRGLKGSKGEKGEDGFPGFKGDMGLK-GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 787

Query: 461 PTG 463
           P+G
Sbjct: 788 PSG 790



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 85/337 (25%), Positives = 103/337 (30%), Gaps = 81/337 (24%)

Query: 140 GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFR--PARQRRTRRPARALNSGQWSPGE-GR 196
           G +G+ G P  +  G  V GP GP   P G    P  Q  T  P          PG+ G 
Sbjct: 384 GEKGQKGEPAVVEPGMLVEGPPGP-AGPAGIMGPPGLQGPTGPPG--------DPGDRGP 434

Query: 197 RAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDK 256
               GL    P  +G+P                  G PGT+        L     G   K
Sbjct: 435 PGRPGL----PGADGLP------------------GPPGTMLM------LPFRYGGDGSK 466

Query: 257 TPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSP------PRSLVAPSESGS 310
            P  S +     A+                 AR+  R  P P      P  +  P  SG+
Sbjct: 467 GPTISAQEAQAQAILQQ--------------ARIALRGPPGPMGLTGRPGPVGGPGSSGA 512

Query: 311 AGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAP--HSLPPPPPFRTGRGEGGGGGSRA 368
            G  G   G   PR   G     G+ G+  R GA     +P  P  +  RG  G  G   
Sbjct: 513 KGESGDP-GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPG 571

Query: 369 DVTAGRARPRRRRWEPLRAQRSGAR--PGAPAPPLPCLPPAAVCHALAGAGAPGGRLELG 426
           D   G    R  +  P      G R   G   P             L G   P G L   
Sbjct: 572 D--KGHRGERGPQGPPGPPGDDGMRGEDGEIGP-----------RGLPGEAGPRGLLGPR 618

Query: 427 LSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
            +PG     G         PP P    GP   PGP G
Sbjct: 619 GTPGAP---GQPGMAGVDGPPGPKGNMGPQGEPGPPG 652



 Score = 36.6 bits (83), Expect = 0.053
 Identities = 88/344 (25%), Positives = 109/344 (31%), Gaps = 67/344 (19%)

Query: 139  VGAEGKGG--GPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-- 194
            VG  G  G  GP+        +GPQGP           ++    P  A N G   PGE  
Sbjct: 1176 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG--EPGEAGNPGP--PGEAG 1231

Query: 195  -----GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNT 249
                 G R   G  EAGP     P +     ++         G+PG +    D       
Sbjct: 1232 VGGPKGERGEKG--EAGP-----PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1284

Query: 250  CAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESG 309
               G+D       E  DP     P    + G               P PP     P  +G
Sbjct: 1285 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP--------------PGPPGKRGPPGAAG 1330

Query: 310  SAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRAD 369
            + GR+G         EK       G KG+    G P    P  P      +G  G    +
Sbjct: 1331 AEGRQG---------EK-------GAKGEAGAEGPPGKTGPVGP------QGPAGKPGPE 1368

Query: 370  VTAGRARPRRRRWEPLRAQRSGARPGAPAPP-LPCLPPAAVCHALAG-------AGAPGG 421
               G   P   +  P  A + G  PG   PP LP L          G        G PG 
Sbjct: 1369 GLRGIPGPVGEQGLPGAAGQDGP-PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1427

Query: 422  RLELGLS--PGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
            + E G    PGT+   G         P  PL   GP  LPGP G
Sbjct: 1428 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1471


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 85/347 (24%), Positives = 107/347 (30%), Gaps = 55/347 (15%)

Query: 122  GPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRP 181
            GPA    S  E   +  +G  G+ G     G     NGP GP        P  Q     P
Sbjct: 1114 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE----NGPPGP--------PGLQGPVGAP 1161

Query: 182  ARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSV 241
              A   G+  P  G++   G ++      G P             L    G PG    + 
Sbjct: 1162 GIAGGDGEPGP-RGQQGMFG-QKGDEGARGFPGPPGPI------GLQGLPGPPGEKGENG 1213

Query: 242  DIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPK-QLGSLSLELPARLPTRC-LPSPP 299
            D+  +           PP  +    P+    P  P   +GS+        P     P PP
Sbjct: 1214 DVGPMG-------PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP 1266

Query: 300  RSLVAPSESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTG 357
                     G  G +G  G  G A P    G     G KG    +G P    PP      
Sbjct: 1267 GEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPA 1326

Query: 358  RGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAG 417
              +G GG    D   G+  P     E           G P PP    PP A       AG
Sbjct: 1327 GQDGVGGDKGEDGDPGQPGPPGPSGEA----------GPPGPPGKRGPPGA-------AG 1369

Query: 418  APGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGL 464
            A G + E G        +G   A        P+   GP   PGP GL
Sbjct: 1370 AEGRQGEKGA-------KGEAGAEGPPGKTGPVGPQGPAGKPGPEGL 1409



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 91/345 (26%), Positives = 115/345 (33%), Gaps = 80/345 (23%)

Query: 140  GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-GRRA 198
            G +GK G P   G    V GPQGP        P  +R    P          PGE G   
Sbjct: 955  GFQGKTGPPGPGG----VVGPQGPTGETG---PIGERGHPGPPGP-------PGEQGLPG 1000

Query: 199  ALGLEEA--GPSLEGIPSSEWDTFSRD---KRSLLSSHGSPGTIQSSVDIPSLTNTCAGG 253
            A G E A   P  +GI   +     R    +R L  + G+PG                GG
Sbjct: 1001 AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGL--------------KGG 1046

Query: 254  KDKTPPFSQEVDDPHALSSPFFPKQLGSLS-LELPARLPTRCLPSPPRSLVAPSESGSAG 312
            +    P       P  + SP      G+   + LP R   +  P P     AP E G  G
Sbjct: 1047 EGPQGP-------PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1099

Query: 313  RRG-----------GTNGVATPREKLGGKRGVGRKGQ-GTRLGAPHSLPPPPPFRTGRGE 360
              G           G  G A    + G K  +G  GQ G++     + PP PP   G   
Sbjct: 1100 PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1159

Query: 361  GGGGGSRADVTAGRARPRRRRWEPLRAQRS--GARPGAPAPPLPCLPPAAVCHALAGAGA 418
              G      +  G   P  R  + +  Q+   GAR G P PP P          +   G 
Sbjct: 1160 APG------IAGGDGEPGPRGQQGMFGQKGDEGAR-GFPGPPGP----------IGLQGL 1202

Query: 419  PGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
            PG        PG +   G    +    PP P    GP    GP G
Sbjct: 1203 PG-------PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQG 1240



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 82/332 (24%), Positives = 98/332 (29%), Gaps = 45/332 (13%)

Query: 145  GGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLEE 204
            G GP      R   GPQGP  +P    P        P +    G   PG+        + 
Sbjct: 908  GDGPPGPPGERGPQGPQGPVGFPGPKGPPGP-----PGKDGLPGH--PGQRGETGFQGKT 960

Query: 205  AGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEV 264
              P   G+   +  T            G PG       +P          D  P      
Sbjct: 961  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGP-PGEQGLPGAAGKEGAKGDPGPQGISGK 1019

Query: 265  DDPHALSSPFFPKQLGSLSLE-LPARLPTRCLPSPPRSLVAPSESGSAGRRG-----GTN 318
            D P  L    FP + G    +  P          PP  + +P E GSAG  G     G  
Sbjct: 1020 DGPAGLRG--FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1077

Query: 319  GVATPREKLGGKRGVGRKGQGTRLG-----APHSLPPPPPFRTGRGEGGGGGSRADVTAG 373
            G   P    G K   G KG     G      P  LP P       GE G  G        
Sbjct: 1078 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG----- 1132

Query: 374  RARPRRRRWEPLRAQRSG--ARPGAPAPPLPCLPPAAVCHALAGAGAPGGRLELGLSPGT 431
                     EP +    G     G P PP     P        G G PG R + G+    
Sbjct: 1133 ---------EPGQKGSKGDKGENGPPGPP-GLQGPVGAPGIAGGDGEPGPRGQQGMFGQ- 1181

Query: 432  RLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
               +G   A     PP P+   G   LPGP G
Sbjct: 1182 ---KGDEGARGFPGPPGPIGLQG---LPGPPG 1207



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 88/363 (24%), Positives = 119/363 (32%), Gaps = 93/363 (25%)

Query: 119 PAGGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRT 178
           P GGP +              GA+G+ G P   G  R V GP GP   P           
Sbjct: 542 PVGGPGSS-------------GAKGESGDPGPQGP-RGVQGPPGPTGKPG---------- 577

Query: 179 RRPARALNSGQWSPGE-GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTI 237
           +R     + G+  PGE G +   G +       G+P    D   R +R      G PG  
Sbjct: 578 KRGRPGADGGRGMPGEPGAKGDRGFD-------GLPGLPGDKGHRGERGPQGPPGPPG-- 628

Query: 238 QSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPS 297
                     +    G+D                      ++G      P  LP     +
Sbjct: 629 ----------DDGMRGEDG---------------------EIG------PRGLPGE---A 648

Query: 298 PPRSLVAP-SESGSAGRRG--GTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPF 354
            PR L+ P    G+ G+ G  G +G   P+  +G +   G  GQ    G P  LP P   
Sbjct: 649 GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPG-PQGLPGPQGP 707

Query: 355 RTGRGEGG--GGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAV--- 409
               GE G  G    A +      P     E    ++    P  P  P+    P  V   
Sbjct: 708 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 767

Query: 410 --CHALAGA-------GAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPG 460
                L G+       G PG + ++GL  G R   G         P  P  R GP   PG
Sbjct: 768 DGVRGLKGSKGEKGEDGFPGFKGDMGLK-GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 826

Query: 461 PTG 463
           P+G
Sbjct: 827 PSG 829



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 85/337 (25%), Positives = 103/337 (30%), Gaps = 81/337 (24%)

Query: 140 GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFR--PARQRRTRRPARALNSGQWSPGE-GR 196
           G +G+ G P  +  G  V GP GP   P G    P  Q  T  P          PG+ G 
Sbjct: 423 GEKGQKGEPAVVEPGMLVEGPPGP-AGPAGIMGPPGLQGPTGPPG--------DPGDRGP 473

Query: 197 RAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDK 256
               GL    P  +G+P                  G PGT+        L     G   K
Sbjct: 474 PGRPGL----PGADGLP------------------GPPGTMLM------LPFRYGGDGSK 505

Query: 257 TPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSP------PRSLVAPSESGS 310
            P  S +     A+                 AR+  R  P P      P  +  P  SG+
Sbjct: 506 GPTISAQEAQAQAILQQ--------------ARIALRGPPGPMGLTGRPGPVGGPGSSGA 551

Query: 311 AGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAP--HSLPPPPPFRTGRGEGGGGGSRA 368
            G  G   G   PR   G     G+ G+  R GA     +P  P  +  RG  G  G   
Sbjct: 552 KGESGDP-GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPG 610

Query: 369 DVTAGRARPRRRRWEPLRAQRSGAR--PGAPAPPLPCLPPAAVCHALAGAGAPGGRLELG 426
           D   G    R  +  P      G R   G   P             L G   P G L   
Sbjct: 611 D--KGHRGERGPQGPPGPPGDDGMRGEDGEIGP-----------RGLPGEAGPRGLLGPR 657

Query: 427 LSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
            +PG     G         PP P    GP   PGP G
Sbjct: 658 GTPGAP---GQPGMAGVDGPPGPKGNMGPQGEPGPPG 691



 Score = 36.6 bits (83), Expect = 0.053
 Identities = 88/344 (25%), Positives = 109/344 (31%), Gaps = 67/344 (19%)

Query: 139  VGAEGKGG--GPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-- 194
            VG  G  G  GP+        +GPQGP           ++    P  A N G   PGE  
Sbjct: 1215 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG--EPGEAGNPGP--PGEAG 1270

Query: 195  -----GRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNT 249
                 G R   G  EAGP     P +     ++         G+PG +    D       
Sbjct: 1271 VGGPKGERGEKG--EAGP-----PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1323

Query: 250  CAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESG 309
               G+D       E  DP     P    + G               P PP     P  +G
Sbjct: 1324 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP--------------PGPPGKRGPPGAAG 1369

Query: 310  SAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRAD 369
            + GR+G         EK       G KG+    G P    P  P      +G  G    +
Sbjct: 1370 AEGRQG---------EK-------GAKGEAGAEGPPGKTGPVGP------QGPAGKPGPE 1407

Query: 370  VTAGRARPRRRRWEPLRAQRSGARPGAPAPP-LPCLPPAAVCHALAG-------AGAPGG 421
               G   P   +  P  A + G  PG   PP LP L          G        G PG 
Sbjct: 1408 GLRGIPGPVGEQGLPGAAGQDGP-PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1466

Query: 422  RLELGLS--PGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
            + E G    PGT+   G         P  PL   GP  LPGP G
Sbjct: 1467 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1510


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 52/166 (31%), Positives = 59/166 (35%), Gaps = 34/166 (20%)

Query: 306 SESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSL-PPPPPFRTGR------ 358
           S  G AG  GG++  A P+   G  R  G    G R   P     PPPPF  G+      
Sbjct: 181 SGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPP 240

Query: 359 -GEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLPPAAVCHALAGAG 417
            G  G  G       G+  P      P R  R         PP P L P          G
Sbjct: 241 LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDR---------PPPPVLFP----------G 281

Query: 418 APGGRLELGLSPGTRLIRGGGAAVPTAAPP--APLPRWGPGPLPGP 461
            P G+  LG  P      G    VP   PP   P P+ GP P PGP
Sbjct: 282 QPFGQPPLGPLP-----PGPPPPVPGYGPPPGPPPPQQGPPPPPGP 322



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 25/77 (32%), Positives = 29/77 (37%), Gaps = 10/77 (12%)

Query: 105 TVTSPSRQSETQITPAGGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPD 164
           T  S     E +  P GG          S+     G  G+G  P A+  G R  GP GP 
Sbjct: 174 TTQSGQMSGEGKAGPPGG---------SSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPG 224

Query: 165 RWPNGFRPARQRRTRRP 181
             P  F PA Q   R P
Sbjct: 225 GPPPPF-PAGQTPPRPP 240


>gi|239757942 PREDICTED: hypothetical protein XP_002346387 [Homo
           sapiens]
          Length = 239

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 66/207 (31%), Positives = 76/207 (36%), Gaps = 33/207 (15%)

Query: 296 PSPP-RSLVAPSESGSAGRRGGTNGVATPREKLGGKRG-------VGRKGQGTRLGAP-- 345
           PSP   SL+A     S    G     A  R   GGK G         R G+    G P  
Sbjct: 36  PSPVLSSLMAGLSLRSPEVVGRVASRARARTWEGGKEGHAAVPQPATRSGRLGVWGGPLR 95

Query: 346 HSLPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPCLP 405
           HS  P P  +  +  GGGGG      AGR   R R     R +        P PP   L 
Sbjct: 96  HSWAPRPR-QASQTRGGGGGPSLPGPAGRPSGRSRSRVGARGRLPSGGSHLPQPPRS-LA 153

Query: 406 PAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTGLF 465
            A+   A+A         ELGLS G R         PT APP P PR    P P      
Sbjct: 154 AASAWQAVAR--------ELGLS-GPR---------PTEAPPFPAPRVRAPPPPQRPAQL 195

Query: 466 DLSVGVSAASSSLGSTELEKNMGSGGG 492
            L  G+    +SLG T   +  G G G
Sbjct: 196 RLLAGLRPVVTSLGVT---RRRGRGAG 219


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 79/275 (28%), Positives = 99/275 (36%), Gaps = 79/275 (28%)

Query: 222 RDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSP---FFPKQ 278
           R  RS    + SPG  Q S+  P+  +   GG D +P        P A  +P   F  + 
Sbjct: 615 RPSRSSPGLYTSPG--QDSLQ-PTAVSPPYGG-DISPVSPSRAWSPRAKQAPRPSFSTRN 670

Query: 279 LGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGG--KRGVGRK 336
            G  + +    LPT    SPP                 T G + P   L G    G    
Sbjct: 671 AGIEAQDRRESLPT----SPP----------------WTPGASRPPSSLDGWVSPGPWEP 710

Query: 337 GQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAGRARP-----------------RR 379
           G+G+ + +P  LPPPPP      E      R +     ARP                 RR
Sbjct: 711 GRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPET---EARPPSRQLQALLARNIINAARR 767

Query: 380 RRWEPLRAQRSGARPGAP--APPLPCLPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGG 437
           +   P  A     RP +P  APP P  PP            P  R+    SP  +  R G
Sbjct: 768 KSASPRSAGAENPRPFSPPRAPPPPPPPP-----------PPPPRMR---SP--QPARPG 811

Query: 438 GAAVPTAA----PPAPLPRWGP-------GPLPGP 461
            AAVP AA    P +PLP  GP        PLP P
Sbjct: 812 SAAVPGAAFAPIPRSPLPA-GPSSCTSPRSPLPAP 845


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 47/178 (26%), Positives = 63/178 (35%), Gaps = 11/178 (6%)

Query: 296 PSPPRSLVAPSESGSAGRRGGTNG-----VATPREKLGGKRGVGRKGQGTRLGAPHSLPP 350
           PS      +P  +G +G+R G +G       +P +K        R         P +   
Sbjct: 302 PSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGK 361

Query: 351 PPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRA-----QRSGARPGAPAPPLPCLP 405
             P         G G RA   AGR R RRRR    R+     +R G R   PAPP     
Sbjct: 362 ESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSR 421

Query: 406 PAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAAVPTAAPPAPLPRWGPGPLPGPTG 463
             +   + + +G+  G    G  PG+    GG        PP   P     P PG  G
Sbjct: 422 SLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPA-STSPSPGAHG 478



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 65/254 (25%), Positives = 83/254 (32%), Gaps = 71/254 (27%)

Query: 148 PQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLEEAGP 207
           P + GRG R  G  G           R+RR RR  R+ +S       GRR        G 
Sbjct: 370 PSSQGRGGRAAGGAG----------RRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRG- 418

Query: 208 SLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDP 267
                 SS   + +R      S  G+PG                       P S+     
Sbjct: 419 ------SSRSLSRARSSSDSGSGRGAPGP-------------------GPEPGSERGHGG 453

Query: 268 HALSSPFFPKQLGSLSLELPARL-PTRCLPSPPRSLVAPSESGSAGRRGGTNGVATPRE- 325
           H           G  + E P R  P    PSP          G+ GRRGG  G ++ R  
Sbjct: 454 H-----------GKRAKERPPRARPASTSPSP----------GAHGRRGGPEGKSSSRSP 492

Query: 326 -----KLGGKRGVGRKGQGTRLGAPHS-----LPPPPPFRTGRGEGGGGGSRADVTAGRA 375
                     R   +    +    PHS      P  P  R   GEG    S A+ T  RA
Sbjct: 493 GPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEAT--RA 550

Query: 376 RPRRRRWEPLRAQR 389
           R R R + P+R +R
Sbjct: 551 RRRSRSYSPIRKRR 564



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 61/243 (25%), Positives = 80/243 (32%), Gaps = 28/243 (11%)

Query: 165 RWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDK 224
           R P+   P  +   R+     +SG  SP            +G S  G P     +  R  
Sbjct: 273 RSPSRLSPKHRDEGRKTGSQRSSGSRSPSP----------SGGSGWGSPQRNGGSGQRS- 321

Query: 225 RSLLSSHGS-PGTIQSSVDIPSLTNTC----AGGKDKTPPFSQEVDDPHALSSPFFPKQL 279
                +HG  PG+  S  D PS  +      A     TPP ++  + P   S+P    + 
Sbjct: 322 ----GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPP-ARGKESPSPRSAPSSQGRG 376

Query: 280 GSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQG 339
           G  +     R   R      RS      S SA RR G      P    G  R + R    
Sbjct: 377 GRAAGGAGRRRRRRRRRRRSRS------SASAPRRRGRRR-PRPAPPRGSSRSLSRARSS 429

Query: 340 TRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAP 399
           +  G+    P P P        GG G RA     RARP      P    R G   G  + 
Sbjct: 430 SDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSS 489

Query: 400 PLP 402
             P
Sbjct: 490 RSP 492



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 7/117 (5%)

Query: 296 PSPPR-SLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPP---P 351
           P+PPR S  + S + S+   G   G   P  + G +RG G  G+  +   P + P    P
Sbjct: 413 PAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSP 472

Query: 352 PPFRTGR--GEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPA-PPLPCLP 405
            P   GR  G  G   SR+     R+    R     R++ +  RP +P+  P P  P
Sbjct: 473 SPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKP 529


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 74/297 (24%), Positives = 110/297 (37%), Gaps = 42/297 (14%)

Query: 108  SPSRQSETQITPAGGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWP 167
            SP  +SE+  +P        DS A+++  LR  +   G  P+   + R       P R  
Sbjct: 1552 SPQERSESDSSP--------DSKAKTRTPLRQRSRS-GSSPEVDSKSRL-----SPRRSR 1597

Query: 168  NGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSL 227
            +G  P  + + R   RA +    SP          E   P+   +P       S   R  
Sbjct: 1598 SGSSPEVKDKPRAAPRAQSGSDSSP----------EPKAPAPRALPRRSRSGSSSKGRGP 1647

Query: 228  LSSHGSPGTIQSSVDIPSLTNTCAGGKDKTP-PFSQEVDDPHALSSPFFPK--------- 277
             S  GS  T +SS + P  + T   G   +P P ++    P   SS   P+         
Sbjct: 1648 -SPEGSSST-ESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSR 1705

Query: 278  --QLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGR 335
              +  S S E  +R P R   SP  S   P+E   + RR      ++PR K   +RG   
Sbjct: 1706 RSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR--RRSASSPRTKTTSRRGRSP 1763

Query: 336  KGQGTRLGAPHSLPPPPPFRTGRGEGGGGGSRADVTAGRARPRRRRWEPLRAQRSGA 392
              +   L    S       RT R     G S++  T+ R +  R R    R +R G+
Sbjct: 1764 SPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQS--TSRRRQRSRSRSRVTRRRRGGS 1818



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 62/224 (27%), Positives = 89/224 (39%), Gaps = 47/224 (20%)

Query: 213 PSSEWDTFSRDKRSLLSSHGSPGTIQSSV--DIPSLTNTCA---GGKDK---TPPFSQEV 264
           PSS ++   +DK+   ++  SP   +SS   + P+ T   A   GG  +   T P SQE 
Sbjct: 331 PSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEP 390

Query: 265 DDPHALSSPFFPK----------QLGSLSLELPARLPTRCL------PSPPRSLVAPSE- 307
            +P + +SP   +          Q  S     P+  PT+        P  P+   AP   
Sbjct: 391 VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH 450

Query: 308 ---SGSAGRRGGTNGVA--------TPREKLG-------GKRGVGRKGQGTRLGAPHSLP 349
              S S   +  ++G A        TP  ++G        KRG  R    T+ G  HS  
Sbjct: 451 REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRG--HSRS 508

Query: 350 PPPPFRTGRGEGGGGGSRADVTAGRAR-PRRRRWEPLR-AQRSG 391
             P +R  R     G SR+    GR+R P+R  W   R  QR G
Sbjct: 509 RSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRG 552



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 88/388 (22%), Positives = 136/388 (35%), Gaps = 82/388 (21%)

Query: 34   VGEQLESWRSWRKDVAGCSSPTPIPEFGAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQD 93
            +G++  S  S   DV   +SP    E  ++  +K+  +    P  Q    G  P    + 
Sbjct: 1533 LGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRT---PLRQRSRSGSSPEVDSKS 1589

Query: 94   RTQPTRIIRGCTVTSPSRQSETQITPAGGPAAFCDSTAESK--------RQLRVGAEGKG 145
            R  P R   G   +SP  + + +  P     +  DS+ E K        R+ R G+  KG
Sbjct: 1590 RLSPRRSRSG---SSPEVKDKPRAAPRAQSGS--DSSPEPKAPAPRALPRRSRSGSSSKG 1644

Query: 146  GGPQALGRGRRVNGPQGPDRWPNGFR-----PARQRRTRRPARALNSGQWSPGEGRRAAL 200
             GP   G     + P+ P +     R     P  + ++R P R   S + SP   R+A  
Sbjct: 1645 RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR-RSSRSSPELTRKAR- 1702

Query: 201  GLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPF 260
             L     S    P +   T  R +RS                 PS+++     K ++   
Sbjct: 1703 -LSRRSRSASSSPETRSRTPPRHRRS-----------------PSVSSPEPAEKSRSSRR 1744

Query: 261  SQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSP-PRSLVAPSESGSAGRRGGTNG 319
             +    P   ++    +                  PSP PR L     S S  RR  T  
Sbjct: 1745 RRSASSPRTKTTSRRGRS-----------------PSPKPRGL---QRSRSRSRREKTR- 1783

Query: 320  VATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRGEGGGGG--------SRADVT 371
                R++ G  +   R+ Q +R  +          R  R   GG G          +  T
Sbjct: 1784 TTRRRDRSGSSQSTSRRRQRSRSRS----------RVTRRRRGGSGYHSRSPARQESSRT 1833

Query: 372  AGRARPRRRRWEPLRAQRSGARPGAPAP 399
            + R R  R R  P   +RS +R  +PAP
Sbjct: 1834 SSRRRRGRSRTPPTSRKRSRSRT-SPAP 1860



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 55/230 (23%), Positives = 80/230 (34%), Gaps = 22/230 (9%)

Query: 21  RRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEFGAAAPTKSALQVQVVPSSQA 80
           +RPG  R    +  G      RS R+  +   SP       +  P +        P+ + 
Sbjct: 538 QRPGWSRSRNTQRRGRS----RSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRR 593

Query: 81  VEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPAGGPAAFCDSTAESKRQLRVG 140
                   R  + RT P R  R  + T   R+S T+      P       + S+   R  
Sbjct: 594 SRSRTPTRRRSRSRT-PARRGRSRSRTPARRRSRTR-----SPVR---RRSRSRSPARRS 644

Query: 141 AEGKGGGPQALGRGR-RVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAA 199
              +   P   GR R R    +G  R     R + + R+R PAR   S   +P  GR  +
Sbjct: 645 GRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRS 704

Query: 200 LGLEEAGPSLEGIP--------SSEWDTFSRDKRSLLSSHGSPGTIQSSV 241
             L   G S    P        SSE    SR  +    S+ SP   +S +
Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.135    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,955,806
Number of Sequences: 37866
Number of extensions: 1831584
Number of successful extensions: 12950
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 1162
Number of HSP's that attempted gapping in prelim test: 9411
Number of HSP's gapped (non-prelim): 3882
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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