BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|10835218 topoisomerase (DNA) III alpha [Homo sapiens] (1001 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|10835218 topoisomerase (DNA) III alpha [Homo sapiens] 2071 0.0 gi|4507635 topoisomerase (DNA) III beta [Homo sapiens] 397 e-110 gi|157388969 nei endonuclease VIII-like 3 [Homo sapiens] 60 1e-08 gi|18375507 apurinic/apyrimidinic endonuclease 2 [Homo sapiens] 46 2e-04 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 40 0.008 gi|218505680 exoribonuclease 2 isoform 1 [Homo sapiens] 39 0.032 gi|47271475 SPOC domain containing 1 [Homo sapiens] 37 0.093 gi|208431824 forkhead box I3 [Homo sapiens] 37 0.12 gi|50083281 KIAA1853 protein [Homo sapiens] 36 0.16 gi|91208420 bassoon protein [Homo sapiens] 35 0.46 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 35 0.46 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 35 0.46 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 35 0.46 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 35 0.46 gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens] 34 0.79 gi|48762934 alpha 2 type I collagen [Homo sapiens] 33 1.0 gi|38150007 small nuclear ribonucleoprotein polypeptide B/B' iso... 33 1.3 gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isof... 33 1.3 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 33 1.3 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 33 1.3 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 33 1.3 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 33 1.3 gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] 33 1.8 gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens] 33 1.8 gi|154146199 sal-like 3 [Homo sapiens] 33 1.8 gi|31881740 solute carrier family 12 (potassium/chloride transpo... 32 2.3 gi|40807471 transcription termination factor, RNA polymerase II ... 32 2.3 gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] 32 3.0 gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 32 3.0 gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 32 3.9 >gi|10835218 topoisomerase (DNA) III alpha [Homo sapiens] Length = 1001 Score = 2071 bits (5365), Expect = 0.0 Identities = 1001/1001 (100%), Positives = 1001/1001 (100%) Query: 1 MIFPVARYALRWLRRPEDRAFSRAAMEMALRGVRKVLCVAEKNDAAKGIADLLSNGRMRR 60 MIFPVARYALRWLRRPEDRAFSRAAMEMALRGVRKVLCVAEKNDAAKGIADLLSNGRMRR Sbjct: 1 MIFPVARYALRWLRRPEDRAFSRAAMEMALRGVRKVLCVAEKNDAAKGIADLLSNGRMRR 60 Query: 61 REGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEK 120 REGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEK Sbjct: 61 REGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEK 120 Query: 121 YCPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVLRARFSE 180 YCPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVLRARFSE Sbjct: 121 YCPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVLRARFSE 180 Query: 181 ITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLIS 240 ITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLIS Sbjct: 181 ITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLIS 240 Query: 241 YGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTHDHKDGIVEFNWKRHRLFNHTACLVLY 300 YGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTHDHKDGIVEFNWKRHRLFNHTACLVLY Sbjct: 241 YGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTHDHKDGIVEFNWKRHRLFNHTACLVLY 300 Query: 301 QLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI 360 QLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI Sbjct: 301 QLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI 360 Query: 361 SYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPT 420 SYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPT Sbjct: 361 SYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPT 420 Query: 421 KYTNNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDV 480 KYTNNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDV Sbjct: 421 KYTNNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDV 480 Query: 481 YPYDHWSDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAE 540 YPYDHWSDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAE Sbjct: 481 YPYDHWSDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAE 540 Query: 541 HIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKK 600 HIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKK Sbjct: 541 HIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKK 600 Query: 601 DKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGTELAQQEDIYPAMPEPIRKCPQ 660 DKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGTELAQQEDIYPAMPEPIRKCPQ Sbjct: 601 DKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGTELAQQEDIYPAMPEPIRKCPQ 660 Query: 661 CNKDMVLKTKKNGGFYLSCMGFPECRSAVWLPDSVLEASRDSSVCPVCQPHPVYRLKLKF 720 CNKDMVLKTKKNGGFYLSCMGFPECRSAVWLPDSVLEASRDSSVCPVCQPHPVYRLKLKF Sbjct: 661 CNKDMVLKTKKNGGFYLSCMGFPECRSAVWLPDSVLEASRDSSVCPVCQPHPVYRLKLKF 720 Query: 721 KRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQH 780 KRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQH Sbjct: 721 KRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQH 780 Query: 781 PQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCNG 840 PQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCNG Sbjct: 781 PQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCNG 840 Query: 841 GSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCS 900 GSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCS Sbjct: 841 GSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCS 900 Query: 901 QPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLES 960 QPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLES Sbjct: 901 QPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLES 960 Query: 961 EARSKRPRASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR 1001 EARSKRPRASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR Sbjct: 961 EARSKRPRASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR 1001 >gi|4507635 topoisomerase (DNA) III beta [Homo sapiens] Length = 862 Score = 397 bits (1020), Expect = e-110 Identities = 264/716 (36%), Positives = 371/716 (51%), Gaps = 51/716 (7%) Query: 33 VRKVLCVAEKNDAAKGIADLLSNGRMRRREGLSKFNKIYEFDYHLYGQNVTMVMTSVSGH 92 ++ VL VAEK A+ IA +LS G + +GL+ ++E+ GQ V MTSV GH Sbjct: 1 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH 60 Query: 93 LLAHDFQMQFRKWQSCNPLVLF-EAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDR 151 ++ DF ++ KW +P LF +A EK +++ K L+ E R C +V+W DCD+ Sbjct: 61 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK 120 Query: 152 EGENIGFEIIHVC-----KAVKPNLQVLRARFSEITPHAVRTACENLTEPDQRVSDAVDV 206 EGENI FE++ KA V RARFS IT + A L EPD + +VD Sbjct: 121 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA 180 Query: 207 RQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEI 266 RQELDLRIG AFTRFQT Q + + L LIS+G CQ PTLGF VER IQ+F PE Sbjct: 181 RQELDLRIGCAFTRFQTKYFQGKYGD-LDSSLISFGPCQTPTLGFCVERHDKIQSFKPET 239 Query: 267 FH--RIKVTHDHKDGIVEFNWKRHRLFNHTACLVLYQLCVEDPMATVVEVRSKPKSKWRP 324 + + KV D KD + +W R R+F+ + + + A V K K+K RP Sbjct: 240 YWVLQAKVNTD-KDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRP 298 Query: 325 QALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPRDLNLTVLVEQQT 384 AL+TVE+ ++AS L + + M+ AE+LYTQGYISYPRTET +P + +L + QQ Sbjct: 299 LALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQA 358 Query: 385 PDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPTKYTNN--LQGDEQRLYEFIVRHFL 442 P W + +L G PR G+ + HPPI P K L GD RLYE+I RHF+ Sbjct: 359 NHPYWADTVKRLLAEGINRPRKGHDAGD-HPPITPMKSATEAELGGDAWRLYEYITRHFI 417 Query: 443 ACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDHWS-DKILPVYEQGSHFQ 501 A S D + ++T+ I E F G +L+ + +V P+ ++ LP ++G F Sbjct: 418 ATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFP 477 Query: 502 PSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLP 561 V+M++ +T+PP LTEA+LI LMEKHGIGTDA+ HI I R YV + +R P Sbjct: 478 VGEVKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKP 537 Query: 562 GHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKKDKFVVLRQQVQKYKQVFIEAV 621 +LG+ LV GY + E+ P +R+ +E L LI GK D VL + +K+ F V Sbjct: 538 TNLGIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFV 597 Query: 622 AKAKKLDEALAQYFGNGTELAQQEDIYPAMPEPIRKCPQCNKDMVLKTKKNGGFYLSCMG 681 +DE + F + LA A +P+ +C +C++ M K + S Sbjct: 598 DSIAGMDELMEVSF---SPLA-------ATGKPLSRCGKCHRFMKYIQAKPSRLHCS--- 644 Query: 682 FPECRSAVWLPDS------------------VLEAS----RDSSVCPVCQPHPVYR 715 C LP + VL +S + +CP C HP +R Sbjct: 645 --HCDETYTLPQNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFR 698 >gi|157388969 nei endonuclease VIII-like 3 [Homo sapiens] Length = 605 Score = 59.7 bits (143), Expect = 1e-08 Identities = 41/132 (31%), Positives = 51/132 (38%), Gaps = 46/132 (34%) Query: 820 VLLTVRKEGPNRGRQFFKC---NGGSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPG 876 +L VRK+G N+GRQF+ C C FF WAD P Sbjct: 515 ILRVVRKDGENKGRQFYACPLPREAQCGFFEWADLSFP---------------------- 552 Query: 877 PGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWV 936 F N G + S +TV K GPN G+ F C +E+QC FFQW Sbjct: 553 -------FCNHG------------KRSTMKTVLKIGPNNGKNFFVCPLGKEKQCNFFQWA 593 Query: 937 DENTAPGTSGAP 948 + PG P Sbjct: 594 E--NGPGIKIIP 603 Score = 57.8 bits (138), Expect = 5e-08 Identities = 27/52 (51%), Positives = 32/52 (61%), Gaps = 4/52 (7%) Query: 886 NPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVD 937 NP S + LC + R V+KDG NKGRQF+ C PRE QCGFF+W D Sbjct: 501 NPDSPRCSKHNRLC----ILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD 548 Score = 45.1 bits (105), Expect = 3e-04 Identities = 22/46 (47%), Positives = 28/46 (60%), Gaps = 4/46 (8%) Query: 813 CNCGQEAVLLTVRKEGPNRGRQFFKCNGG---SCNFFLWADSPNPG 855 CN G+ + + TV K GPN G+ FF C G CNFF WA++ PG Sbjct: 554 CNHGKRSTMKTVLKIGPNNGKNFFVCPLGKEKQCNFFQWAEN-GPG 598 >gi|18375507 apurinic/apyrimidinic endonuclease 2 [Homo sapiens] Length = 518 Score = 45.8 bits (107), Expect = 2e-04 Identities = 20/41 (48%), Positives = 26/41 (63%), Gaps = 6/41 (14%) Query: 901 QPSVTRTVQKDGPNKGRQFHTCAKPR------EQQCGFFQW 935 +P V RTV+K GPN GR+F+ CA+PR +C FF W Sbjct: 474 EPCVMRTVKKPGPNLGRRFYMCARPRGPPTDPSSRCNFFLW 514 Score = 39.7 bits (91), Expect = 0.014 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 10/76 (13%) Query: 784 ADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQE-AVLLTVRKEGPNRGRQFFKC---- 838 A + + K L + AG + C +E V+ TV+K GPN GR+F+ C Sbjct: 440 AKTSEAKDEKELRTSFWKSVLAGPLRTPLCGGHREPCVMRTVKKPGPNLGRRFYMCARPR 499 Query: 839 -----NGGSCNFFLWA 849 CNFFLW+ Sbjct: 500 GPPTDPSSRCNFFLWS 515 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 40.4 bits (93), Expect = 0.008 Identities = 32/108 (29%), Positives = 36/108 (33%), Gaps = 19/108 (17%) Query: 850 DSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQ 909 D+ PG GPP LA P PPGP G G PG +GT L P + Sbjct: 676 DAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLG 735 Query: 910 KDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRT 957 GP + E PG G P G RG T Sbjct: 736 SPGPKGDK-------------------GEPGGPGADGVPGKDGPRGPT 764 Score = 33.9 bits (76), Expect = 0.79 Identities = 17/40 (42%), Positives = 21/40 (52%) Query: 855 GAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSG 894 G GGPP +A P G+ PPGP G G+PG +G Sbjct: 834 GEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAG 873 Score = 30.4 bits (67), Expect = 8.7 Identities = 31/111 (27%), Positives = 39/111 (35%), Gaps = 11/111 (9%) Query: 853 NPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKDG 912 +PG GPP P A PPGP +G G G SG + + G Sbjct: 196 SPGYQGPPG---EPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKG 252 Query: 913 P--------NKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRG 955 P KG + + + G EN PG +GAP G RG Sbjct: 253 PAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRG 303 >gi|218505680 exoribonuclease 2 isoform 1 [Homo sapiens] Length = 691 Score = 38.5 bits (88), Expect = 0.032 Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 7/57 (12%) Query: 799 LPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKC-------NGGSCNFFLW 848 L P +G+ C CG+ + L V GPN G+ F+ C N C +F W Sbjct: 583 LQEPWKSGKMTPPLCKCGRRSKRLVVSNNGPNHGKVFYCCPIGKYQENRKCCGYFKW 639 Score = 35.8 bits (81), Expect = 0.21 Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 4/43 (9%) Query: 897 CLCSQPSVTRTVQKDGPNKGRQFHTCAKPREQQ----CGFFQW 935 C C + S V +GPN G+ F+ C + Q+ CG+F+W Sbjct: 597 CKCGRRSKRLVVSNNGPNHGKVFYCCPIGKYQENRKCCGYFKW 639 >gi|47271475 SPOC domain containing 1 [Homo sapiens] Length = 1216 Score = 37.0 bits (84), Expect = 0.093 Identities = 43/162 (26%), Positives = 62/162 (38%), Gaps = 16/162 (9%) Query: 741 DDTLREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQHPQPADSRQTGSSKALAQTLP 800 DD+ L R +G P RA RL + ++ + +P ++R G S Sbjct: 128 DDSCPRKLCSRSAGLPERALACRERLAGVEEVSCL------RPREARDGGMSSPGCDRRS 181 Query: 801 PPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCNGGSCNFFLWADSPNPG----- 855 P + E + V + VRK+ +G +C G+ +F LW D G Sbjct: 182 PTLSKEEPPGRPLTSSPDPVPVRVRKKWRRQGAHS-ECEEGAGDF-LWLDQSPRGDNLLS 239 Query: 856 AGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSC 897 G PP +A SLG P P PG+ GSG C Sbjct: 240 VGDPPQVADLE---SLGGPCRPPSPKDTGSGPGEPGGSGAGC 278 >gi|208431824 forkhead box I3 [Homo sapiens] Length = 420 Score = 36.6 bits (83), Expect = 0.12 Identities = 21/55 (38%), Positives = 27/55 (49%), Gaps = 5/55 (9%) Query: 842 SCNFFLWADSPNPGAGGPPALAYRPLGASLGC---PPGPGIHLGGFGNPGDGSGS 893 + N +LW + P G GGPP+ A A LG PP PG G F P +G+ Sbjct: 49 AANPYLWLNGP--GVGGPPSAAAAAAAAYLGAPPPPPPPGAAAGPFLQPPPAAGT 101 >gi|50083281 KIAA1853 protein [Homo sapiens] Length = 611 Score = 36.2 bits (82), Expect = 0.16 Identities = 50/212 (23%), Positives = 77/212 (36%), Gaps = 31/212 (14%) Query: 774 RMDNSQHPQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGR 833 R D +H + + SR S + P + + ES +C R P G+ Sbjct: 163 RRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRH-------RGRSPEEGQ 215 Query: 834 QFFKCNGGSCNFFLWADSPNPGAGGPPALAYRPLG--ASLGCPPGPGIHLGGFGNPGD-- 889 + + + C+ L DSP + PP+ + LG ++ G G G F Sbjct: 216 KSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPL 275 Query: 890 ----------GSGSGTSCLCSQPSV-TRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDE 938 SG+ TS S PS T + + G KG +K RE G Sbjct: 276 TTSRGRSQEYDSGNDTS---SPPSTQTSSARSRGQEKGSPSGGLSKSRELNSG------N 326 Query: 939 NTAPGTSGAPSWTGDRGRTLESEARSKRPRAS 970 + G S S ++G LE+ + + R R S Sbjct: 327 TSDSGNSFTTSSPQNKGAMLENLSPTSRGRES 358 >gi|91208420 bassoon protein [Homo sapiens] Length = 3926 Score = 34.7 bits (78), Expect = 0.46 Identities = 41/140 (29%), Positives = 53/140 (37%), Gaps = 23/140 (16%) Query: 852 PNPGAGGPPA-------LAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSV 904 P PGAG PP+ L S PP PG G PG G G G++ P Sbjct: 29 PGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPG----PGPGPGPGSTSRRLDPKE 84 Query: 905 TRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARS 964 Q+ +Q E E A G +G + G R RTL+ ++R+ Sbjct: 85 PLGNQRAASPTPKQASATTPGHESP-------RETRAQGPAGQEA-DGPR-RTLQVDSRT 135 Query: 965 KRPRAS---SSDMGSTAKKP 981 +R S S D GST P Sbjct: 136 QRSGRSPSVSPDRGSTPTSP 155 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 34.7 bits (78), Expect = 0.46 Identities = 35/107 (32%), Positives = 38/107 (35%), Gaps = 21/107 (19%) Query: 854 PGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSC-----LCSQPSVTRTV 908 PG GPP L P GA++ PPGP G G GD G S L QP Sbjct: 376 PGIQGPPGLP-GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLP 434 Query: 909 QKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRG 955 GP A P DE PG G P GD+G Sbjct: 435 GPPGP---------AGPHIPPS------DEICEPGPPGPPGSPGDKG 466 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 34.7 bits (78), Expect = 0.46 Identities = 35/107 (32%), Positives = 38/107 (35%), Gaps = 21/107 (19%) Query: 854 PGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSC-----LCSQPSVTRTV 908 PG GPP L P GA++ PPGP G G GD G S L QP Sbjct: 376 PGIQGPPGLP-GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLP 434 Query: 909 QKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRG 955 GP A P DE PG G P GD+G Sbjct: 435 GPPGP---------AGPHIPPS------DEICEPGPPGPPGSPGDKG 466 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 34.7 bits (78), Expect = 0.46 Identities = 35/107 (32%), Positives = 38/107 (35%), Gaps = 21/107 (19%) Query: 854 PGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSC-----LCSQPSVTRTV 908 PG GPP L P GA++ PPGP G G GD G S L QP Sbjct: 376 PGIQGPPGLP-GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLP 434 Query: 909 QKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRG 955 GP A P DE PG G P GD+G Sbjct: 435 GPPGP---------AGPHIPPS------DEICEPGPPGPPGSPGDKG 466 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 34.7 bits (78), Expect = 0.46 Identities = 36/124 (29%), Positives = 42/124 (33%), Gaps = 28/124 (22%) Query: 850 DSPNPGAGGPPALAYRP-------------LGASLGCPPGPGIH-----LGGFGNPGDGS 891 DS GA GPP P L LG P PG+ G G+PGD Sbjct: 1233 DSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVG 1292 Query: 892 GSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWT 951 G G +P K GP+ H + RE + G PG G P T Sbjct: 1293 GPGPPGASGEPGAPGPPGKRGPSG----HMGREGREGEKG------AKGEPGPDGPPGRT 1342 Query: 952 GDRG 955 G G Sbjct: 1343 GPMG 1346 >gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens] Length = 796 Score = 33.9 bits (76), Expect = 0.79 Identities = 49/192 (25%), Positives = 64/192 (33%), Gaps = 45/192 (23%) Query: 761 QPSGRLQANQSLNRMDNSQHPQ----PADSRQTGSSKALAQTL--------------PPP 802 Q + Q Q LN +D S P P+ + G S A A PPP Sbjct: 117 QQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPP 176 Query: 803 TAAGESNSVTCNC-----GQEAVLLTVRKEGPNR-GRQFFKCNGGSCNFF--------LW 848 + S+S T G +EGP RQ + + + L Sbjct: 177 PVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLV 236 Query: 849 ADSPNPGAGGPPALAYRP----------LGASLGCPPGPGIHLGGFGNP---GDGSGSGT 895 PNPG GG P L P ++ PP P LG G P G+ G Sbjct: 237 TGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAPGGP 296 Query: 896 SCLCSQPSVTRT 907 +CL P V+ T Sbjct: 297 ACLGGTPGVSAT 308 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 33.5 bits (75), Expect = 1.0 Identities = 33/111 (29%), Positives = 37/111 (33%), Gaps = 9/111 (8%) Query: 854 PGAGGPPALAYRPLGASLGCPP----GPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQ 909 PG GG A Y G LG P GP G G PG G + +P T Sbjct: 71 PGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAG 130 Query: 910 KDGP-----NKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRG 955 GP G H R + G PGT G P + G RG Sbjct: 131 ARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRG 181 >gi|38150007 small nuclear ribonucleoprotein polypeptide B/B' isoform B' [Homo sapiens] Length = 240 Score = 33.1 bits (74), Expect = 1.3 Identities = 14/32 (43%), Positives = 18/32 (56%) Query: 851 SPNPGAGGPPALAYRPLGASLGCPPGPGIHLG 882 +P PG GPP P+G +G PPG G +G Sbjct: 183 APPPGMMGPPPGMRPPMGPPMGIPPGRGTPMG 214 >gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isoform B [Homo sapiens] Length = 231 Score = 33.1 bits (74), Expect = 1.3 Identities = 14/32 (43%), Positives = 18/32 (56%) Query: 851 SPNPGAGGPPALAYRPLGASLGCPPGPGIHLG 882 +P PG GPP P+G +G PPG G +G Sbjct: 183 APPPGMMGPPPGMRPPMGPPMGIPPGRGTPMG 214 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 33.1 bits (74), Expect = 1.3 Identities = 40/150 (26%), Positives = 52/150 (34%), Gaps = 23/150 (15%) Query: 853 NPGAGGPPAL-AYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKD 911 N G G P L + L G PPGP LG GNPG+ G P + Sbjct: 971 NRGVPGMPGLKGLKGLPGPAG-PPGPRGDLGSTGNPGEPGLRGI------PGSMGNMGMP 1023 Query: 912 GPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARSKRPRASS 971 G +KG++ G + PG G GD+G SE P + Sbjct: 1024 G-SKGKR------------GTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPT 1070 Query: 972 SDMGSTAKKPRKCSLCH--QPGHTRPFCPQ 999 D G +K + PGH P P+ Sbjct: 1071 GDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 33.1 bits (74), Expect = 1.3 Identities = 40/150 (26%), Positives = 52/150 (34%), Gaps = 23/150 (15%) Query: 853 NPGAGGPPAL-AYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKD 911 N G G P L + L G PPGP LG GNPG+ G P + Sbjct: 971 NRGVPGMPGLKGLKGLPGPAG-PPGPRGDLGSTGNPGEPGLRGI------PGSMGNMGMP 1023 Query: 912 GPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARSKRPRASS 971 G +KG++ G + PG G GD+G SE P + Sbjct: 1024 G-SKGKR------------GTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPT 1070 Query: 972 SDMGSTAKKPRKCSLCH--QPGHTRPFCPQ 999 D G +K + PGH P P+ Sbjct: 1071 GDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 33.1 bits (74), Expect = 1.3 Identities = 40/150 (26%), Positives = 52/150 (34%), Gaps = 23/150 (15%) Query: 853 NPGAGGPPAL-AYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKD 911 N G G P L + L G PPGP LG GNPG+ G P + Sbjct: 971 NRGVPGMPGLKGLKGLPGPAG-PPGPRGDLGSTGNPGEPGLRGI------PGSMGNMGMP 1023 Query: 912 GPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARSKRPRASS 971 G +KG++ G + PG G GD+G SE P + Sbjct: 1024 G-SKGKR------------GTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPT 1070 Query: 972 SDMGSTAKKPRKCSLCH--QPGHTRPFCPQ 999 D G +K + PGH P P+ Sbjct: 1071 GDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 33.1 bits (74), Expect = 1.3 Identities = 40/150 (26%), Positives = 52/150 (34%), Gaps = 23/150 (15%) Query: 853 NPGAGGPPAL-AYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKD 911 N G G P L + L G PPGP LG GNPG+ G P + Sbjct: 971 NRGVPGMPGLKGLKGLPGPAG-PPGPRGDLGSTGNPGEPGLRGI------PGSMGNMGMP 1023 Query: 912 GPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARSKRPRASS 971 G +KG++ G + PG G GD+G SE P + Sbjct: 1024 G-SKGKR------------GTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPT 1070 Query: 972 SDMGSTAKKPRKCSLCH--QPGHTRPFCPQ 999 D G +K + PGH P P+ Sbjct: 1071 GDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100 >gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] Length = 1388 Score = 32.7 bits (73), Expect = 1.8 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 4/53 (7%) Query: 855 GAGGPPALAYRPLGASLGCPPGPGIHLG-GFGNPGDGSGSGTSCLCSQPSVTR 906 G GPP + P PPGPG +G GF D GSG++ L ++P ++R Sbjct: 709 GQAGPPGVMGPPGPPGPPGPPGPGCTMGLGF---EDTEGSGSTQLLNEPKLSR 758 >gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens] Length = 460 Score = 32.7 bits (73), Expect = 1.8 Identities = 30/102 (29%), Positives = 36/102 (35%), Gaps = 6/102 (5%) Query: 881 LGGFGNPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENT 940 L G PG G GS +S SQP + + GR C PR Q + W +E Sbjct: 225 LQGSETPGKGGGSSSSSERSQPGAEGSPETP---PGRCCRCCRAPRLLQA--YSWKEEEE 279 Query: 941 APGTSGAPSWTGDRGRTLESEARSKRPRASSSDMGSTAKKPR 982 S S T G SE K P T + PR Sbjct: 280 EDEGS-MESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPR 320 >gi|154146199 sal-like 3 [Homo sapiens] Length = 1300 Score = 32.7 bits (73), Expect = 1.8 Identities = 33/123 (26%), Positives = 47/123 (38%), Gaps = 8/123 (6%) Query: 692 PDSVLEASRD-----SSVCPVCQPHPVYRLKLKFKRGSLPPTMPLEFVCCIGGCD---DT 743 P S+L SR+ S+VC VC + L+ S P C GC + Sbjct: 961 PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020 Query: 744 LREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQHPQPADSRQTGSSKALAQTLPPPT 803 + +L R P + P+ L +QS + +S P G KA+A PP Sbjct: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080 Query: 804 AAG 806 AG Sbjct: 1081 PAG 1083 >gi|31881740 solute carrier family 12 (potassium/chloride transporters), member 9 [Homo sapiens] Length = 914 Score = 32.3 bits (72), Expect = 2.3 Identities = 14/30 (46%), Positives = 19/30 (63%) Query: 782 QPADSRQTGSSKALAQTLPPPTAAGESNSV 811 +PADS + GSS AL+ PPP A G ++ Sbjct: 649 EPADSTREGSSPALSTLFPPPRAPGSPRAL 678 >gi|40807471 transcription termination factor, RNA polymerase II [Homo sapiens] Length = 1162 Score = 32.3 bits (72), Expect = 2.3 Identities = 13/37 (35%), Positives = 20/37 (54%) Query: 816 GQEAVLLTVRKEGPNRGRQFFKCNGGSCNFFLWADSP 852 G L T ++GPN+G+ F+ C +C+F D P Sbjct: 10 GTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIP 46 >gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] Length = 651 Score = 32.0 bits (71), Expect = 3.0 Identities = 43/171 (25%), Positives = 57/171 (33%), Gaps = 27/171 (15%) Query: 847 LWADSPNPGAGGPPALAYRPLGASLGCPP-----------GPGIHLGGFGNPGDGSGSGT 895 LWA +PN G P A A +LG P GP + G +P GSG+G Sbjct: 372 LWAKTPNQGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGG 431 Query: 896 SCLCSQ--PSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTA---PGTSGAPSW 950 ++ + T D + G F A W A P SG + Sbjct: 432 FAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTV 491 Query: 951 TGDRGRTLESEARSKRPRASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR 1001 G G P A+ + S A PR +PG R P +R Sbjct: 492 NGAPG-----------PPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSR 531 >gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] Length = 753 Score = 32.0 bits (71), Expect = 3.0 Identities = 33/117 (28%), Positives = 41/117 (35%), Gaps = 14/117 (11%) Query: 782 QPADSRQTGSSKALAQTLP--PPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCN 839 +P S Q S A+ T P PP AA ++ N G A GP + Sbjct: 306 KPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNS 365 Query: 840 GGSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTS 896 G +P A PPA P G S P P + G G G G G +S Sbjct: 366 G--------TPAPYAQAVAPPA----PSGPSTTQPRPPSVQPSGGGGGGSGGGGSSS 410 >gi|7662236 TSC22 domain family, member 2 [Homo sapiens] Length = 780 Score = 31.6 bits (70), Expect = 3.9 Identities = 51/206 (24%), Positives = 74/206 (35%), Gaps = 25/206 (12%) Query: 761 QPSGRLQANQSLNRMDNSQHPQPADSRQTG--SSKALAQTLPPPTAAGESN--SVTCNCG 816 QPSG+ + Q + Q P PA TG +S A A TLP T S+ + Sbjct: 373 QPSGQSEYLQQ--HVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGAS 430 Query: 817 QEAVLLTVRKEGPNRGRQFFKCNGGSCNFFLWADSPNP-----GAGGPPALAYRPLGAS- 870 + + GP +G Q C P GAG P ++ +G S Sbjct: 431 SQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSG 490 Query: 871 --LGCPPGPGIHLGGFGN-----PGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCA 923 P GP + G N P S ++ + P+V + + ++ HT Sbjct: 491 PLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQ---SQQLSSHT-- 545 Query: 924 KPREQQCGFFQWVDENTAPGTSGAPS 949 P + Q V APGT AP+ Sbjct: 546 -PVSRSSSIIQHVGLPLAPGTHSAPT 570 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 43,506,151 Number of Sequences: 37866 Number of extensions: 2296117 Number of successful extensions: 8245 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 53 Number of HSP's that attempted gapping in prelim test: 8029 Number of HSP's gapped (non-prelim): 276 length of query: 1001 length of database: 18,247,518 effective HSP length: 112 effective length of query: 889 effective length of database: 14,006,526 effective search space: 12451801614 effective search space used: 12451801614 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.