APEX2 9837

Name: APEX2	Sequence: fasta or formatted (518aa)		NCBI GI: 18375507
Description: apurinic/apyrimidinic endonuclease 2		Referenced in: DNases, Recombination, and DNA Repair
Composition: Amino acid Percentage Count Longest homopolymer A alanine 7.3 38 2 C cysteine 3.5 18 1 D aspartate 4.2 22 1 E glutamate 5.8 30 2 F phenylalanine 4.1 21 2 G glycine 6.8 35 2 H histidine 1.9 10 1 I isoleucine 2.9 15 2 K lysine 4.4 23 2 L leucine 10.0 52 2 M methionine 1.7 9 1 N asparagine 3.9 20 2 P proline 7.5 39 2 Q glutamine 5.0 26 1 R arginine 7.1 37 2 S serine 7.9 41 2 T threonine 5.6 29 1 V valine 6.8 35 2 W tryptophan 1.4 7 1 Y tyrosine 2.1 11 1			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 apurinic/apyrimidinic endonuclease 2 APEX1 0.056 APEX nuclease 1 APEX1 0.056 APEX nuclease 1 APEX1 0.056 APEX nuclease 1 NEIL3 0.023 nei endonuclease VIII-like 3 TOP3A 0.020 topoisomerase (DNA) III alpha DOT1L 0.009 DOT1-like, histone H3 methyltransferase NCOA6 0.008 nuclear receptor coactivator 6 SHANK1 0.008 SH3 and multiple ankyrin repeat domains 1 ERI2 0.008 exoribonuclease 2 isoform 1 HTRA2 0.007 HtrA serine peptidase 2 isoform 1 preproprotein [Homo... HTRA2 0.007 HtrA serine peptidase 2 isoform 2 ADAMTS7 0.007 ADAM metallopeptidase with thrombospondin type 1 mot... KIAA1486 0.007 hypothetical protein LOC57624 LOC100293817 0.007 PREDICTED: similar to hCG1811893 LOC100128084 0.007 PREDICTED: hypothetical protein MLL2 0.007 myeloid/lymphoid or mixed-lineage leukemia 2 MICAL3 0.007 microtubule associated monoxygenase, calponin and L... MLL3 0.006 myeloid/lymphoid or mixed-lineage leukemia 3 PPP1R15B 0.006 protein phosphatase 1, regulatory subunit 15B [Homo... MLXIP 0.006 MLX interacting protein LOC100131880 0.005 PREDICTED: hypothetical protein LOC100131880 0.005 PREDICTED: hypothetical protein IDH3A 0.005 isocitrate dehydrogenase 3 (NAD+) alpha precursor [Ho... TTF2 0.005 transcription termination factor, RNA polymerase II ... USH2A 0.005 usherin isoform B MLL5 0.005 myeloid/lymphoid or mixed-lineage leukemia 5 MLL5 0.005 myeloid/lymphoid or mixed-lineage leukemia 5 SPEN 0.005 spen homolog, transcriptional regulator SPERT 0.005 spermatid associated Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.