Guide to the Human Genome
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Search of human proteins with 23200025

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23200025 tumor necrosis factor receptor superfamily, member
25 isoform 4 precursor [Homo sapiens]
         (372 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23200025 tumor necrosis factor receptor superfamily, member 2...   793   0.0  
gi|4507569 tumor necrosis factor receptor superfamily, member 25...   772   0.0  
gi|23200021 tumor necrosis factor receptor superfamily, member 2...   720   0.0  
gi|23200023 tumor necrosis factor receptor superfamily, member 2...   673   0.0  
gi|23200031 tumor necrosis factor receptor superfamily, member 2...   376   e-104
gi|89142745 tumor necrosis factor receptor superfamily, member 2...   282   4e-76
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi...    96   7e-20
gi|224494019 tumor necrosis factor receptor superfamily, member ...    55   1e-07
gi|224494026 tumor necrosis factor receptor superfamily, member ...    47   3e-05
gi|23238204 tumor necrosis factor receptor superfamily, member 1...    44   2e-04
gi|23238202 tumor necrosis factor receptor superfamily, member 1...    44   2e-04
gi|21361086 tumor necrosis factor receptor superfamily, member 1...    44   3e-04
gi|23200041 tumor necrosis factor receptor superfamily, member 1...    42   7e-04
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]                42   9e-04
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    41   0.002
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...    40   0.003
gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]         39   0.006
gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]         39   0.006
gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]         39   0.006
gi|110611156 laminin, gamma 3 precursor [Homo sapiens]                 39   0.006
gi|119703755 laminin, beta 2 precursor [Homo sapiens]                  39   0.008
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ...    39   0.008
gi|145309326 laminin, gamma 1 precursor [Homo sapiens]                 39   0.010
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]               39   0.010
gi|219842266 usherin isoform B [Homo sapiens]                          38   0.013
gi|219842259 usherin isoform A [Homo sapiens]                          38   0.013
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...    38   0.013
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu...    38   0.017
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu...    38   0.017
gi|145309306 scavenger receptor class F, member 1 isoform 5 prec...    38   0.017

>gi|23200025 tumor necrosis factor receptor superfamily, member 25
           isoform 4 precursor [Homo sapiens]
          Length = 372

 Score =  793 bits (2049), Expect = 0.0
 Identities = 372/372 (100%), Positives = 372/372 (100%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAASQVALE 60
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAASQVALE
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAASQVALE 60

Query: 61  NCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTC 120
           NCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTC
Sbjct: 61  NCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTC 120

Query: 121 LPGFYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYR 180
           LPGFYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYR
Sbjct: 121 LPGFYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYR 180

Query: 181 HCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGY 240
           HCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGY
Sbjct: 181 HCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGY 240

Query: 241 PETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPAR 300
           PETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPAR
Sbjct: 241 PETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPAR 300

Query: 301 RWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGC 360
           RWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGC
Sbjct: 301 RWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGC 360

Query: 361 VEDLRSRLQRGP 372
           VEDLRSRLQRGP
Sbjct: 361 VEDLRSRLQRGP 372


>gi|4507569 tumor necrosis factor receptor superfamily, member 25
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score =  772 bits (1993), Expect = 0.0
 Identities = 372/417 (89%), Positives = 372/417 (89%), Gaps = 45/417 (10%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA------- 53
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA       
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 54  --------------------------------------ASQVALENCSAVADTRCGCKPG 75
                                                 ASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 76  WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 135
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 136 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG 195
           TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG
Sbjct: 181 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG 240

Query: 196 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW 255
           MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
Sbjct: 241 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW 300

Query: 256 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE 315
           DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
Sbjct: 301 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE 360

Query: 316 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP 372
           IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
Sbjct: 361 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP 417


>gi|23200021 tumor necrosis factor receptor superfamily, member 25
           isoform 1 precursor [Homo sapiens]
          Length = 426

 Score =  720 bits (1859), Expect = 0.0
 Identities = 358/426 (84%), Positives = 361/426 (84%), Gaps = 54/426 (12%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA------- 53
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA       
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 54  --------------------------------------ASQVALENCSAVADTRCGCKPG 75
                                                 ASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 76  WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 135
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 136 TS--TLGSCPERCA------AVCGWRQ-MFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK 186
           T   +L   P          +V G R  +FWVQVLLAGLVVPLLLGATLTYTYRHCWPHK
Sbjct: 181 TPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK 240

Query: 187 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 246
           PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA
Sbjct: 241 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 300

Query: 247 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 306
           LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV
Sbjct: 301 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 360

Query: 307 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 366
           RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS
Sbjct: 361 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 420

Query: 367 RLQRGP 372
           RLQRGP
Sbjct: 421 RLQRGP 426


>gi|23200023 tumor necrosis factor receptor superfamily, member 25
           isoform 3 precursor [Homo sapiens]
          Length = 380

 Score =  673 bits (1736), Expect = 0.0
 Identities = 334/417 (80%), Positives = 335/417 (80%), Gaps = 82/417 (19%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA------- 53
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA       
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 54  --------------------------------------ASQVALENCSAVADTRCGCKPG 75
                                                 ASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 76  WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 135
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 136 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG 195
           TSTLGSCPERCAAVCGWRQ                                     +EAG
Sbjct: 181 TSTLGSCPERCAAVCGWRQ-------------------------------------NEAG 203

Query: 196 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW 255
           MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
Sbjct: 204 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW 263

Query: 256 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE 315
           DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
Sbjct: 264 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE 323

Query: 316 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP 372
           IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
Sbjct: 324 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP 380


>gi|23200031 tumor necrosis factor receptor superfamily, member 25
           isoform 7 precursor [Homo sapiens]
          Length = 234

 Score =  376 bits (966), Expect = e-104
 Identities = 182/182 (100%), Positives = 182/182 (100%)

Query: 191 ADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQ 250
           ADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQ
Sbjct: 53  ADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQ 112

Query: 251 VTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLG 310
           VTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLG
Sbjct: 113 VTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLG 172

Query: 311 LREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQR 370
           LREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQR
Sbjct: 173 LREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQR 232

Query: 371 GP 372
           GP
Sbjct: 233 GP 234



 Score =  116 bits (290), Expect = 4e-26
 Identities = 53/53 (100%), Positives = 53/53 (100%)

Query: 1  MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA 53
          MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA
Sbjct: 1  MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA 53


>gi|89142745 tumor necrosis factor receptor superfamily, member 25
           isoform 12 precursor [Homo sapiens]
          Length = 181

 Score =  282 bits (721), Expect = 4e-76
 Identities = 136/181 (75%), Positives = 136/181 (75%), Gaps = 45/181 (24%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA------- 53
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA       
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 54  --------------------------------------ASQVALENCSAVADTRCGCKPG 75
                                                 ASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 76  WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 135
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 136 T 136
           T
Sbjct: 181 T 181


>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
           sapiens]
          Length = 455

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 100/359 (27%), Positives = 139/359 (38%), Gaps = 34/359 (9%)

Query: 36  AGDFHKKIGLFCCRGCPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQP 95
           A + H +  L C +      QV + +C+   DT CGC+       Q     S + F C  
Sbjct: 91  ASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKN-----QYRHYWSENLFQCFN 145

Query: 96  CLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLG-SCPERCAA----VC 150
           C  C  L+    L C  +     TC  GF+   + CVSC        C + C      V 
Sbjct: 146 CSLC--LNGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVK 203

Query: 151 GWRQ----MFWVQVLLAGLVVPLLLGATLTYTYRH---------CWPHKPLVTADEAGME 197
           G       +    V+  GL +  LL   L Y Y+          C    P    +  G  
Sbjct: 204 GTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTT 263

Query: 198 ALTPPPATHLSPLDS-AHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWD 256
                P    SP      TL   P  S    +         P +   +  + P    + D
Sbjct: 264 TKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQGA-D 322

Query: 257 QLPSRALG--PAAAPTLSPESPAGSPAMMLQPGPQ-LYDVMDAVPARRWKEFVRTLGLRE 313
            + + AL   P   P    E  A  P  +    P  LY V++ VP  RWKEFVR LGL +
Sbjct: 323 PILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSD 382

Query: 314 AEIEAVEVEIGR-FRDQQYEMLKRWRQQQP---AGLGAVYAALERMGLDGCVEDLRSRL 368
            EI+ +E++ GR  R+ QY ML  WR++ P   A L  +   L  M L GC+ED+   L
Sbjct: 383 HEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEAL 441


>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
           isoform 1 precursor [Homo sapiens]
          Length = 440

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 80/330 (24%), Positives = 126/330 (38%), Gaps = 48/330 (14%)

Query: 45  LFC--CRGCPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGAL 102
           LFC  C  C +  +V L  C+   +T C C+ G F E         SP  C+ C      
Sbjct: 111 LFCLRCTRCDSG-EVELSPCTTTRNTVCQCEEGTFRE-------EDSPEMCRKC------ 156

Query: 103 HRHTRLLCSRRDTDCGTCLPG------FYEHG---DGCVSCPTSTLGSCPERCAAVCGWR 153
               R  C R     G C P         E G    G V     T+ S P   A+ C   
Sbjct: 157 ----RTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLS 212

Query: 154 QMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG----MEALTPPPATHLSP 209
            +  + V +A +V+ + +    +  ++   P+   + +   G    ++  +  P    + 
Sbjct: 213 GII-IGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAEDNV 271

Query: 210 LDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAP 269
           L+   ++L P    E+   VQ       P  P     L P  +    + P+ A       
Sbjct: 272 LNEIVSILQPTQVPEQEMEVQ------EPAEPTGVNMLSPGESEHLLE-PAEAERSQRRR 324

Query: 270 TLSPESPAGSPAMMLQPGPQLYD-VMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRD 328
            L P +  G P   L+   Q +D   D VP   W+  +R LGL + EI+  + E    RD
Sbjct: 325 LLVPANE-GDPTETLR---QCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRD 380

Query: 329 QQYEMLKRW--RQQQPAGLGAVYAALERMG 356
             Y ML +W  +  + A +  +  ALE +G
Sbjct: 381 TLYTMLIKWVNKTGRDASVHTLLDALETLG 410


>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
           isoform 2 precursor [Homo sapiens]
          Length = 411

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 75/317 (23%), Positives = 112/317 (35%), Gaps = 51/317 (16%)

Query: 45  LFC--CRGCPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGAL 102
           LFC  C  C +  +V L  C+   +T C C+ G F E         SP  C+ C      
Sbjct: 111 LFCLRCTRCDSG-EVELSPCTTTRNTVCQCEEGTFRE-------EDSPEMCRKC------ 156

Query: 103 HRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLL 162
               R  C R     G C P              S +    +    + G      V ++ 
Sbjct: 157 ----RTGCPRGMVKVGDCTPW-------------SDIECVHKESGIIIGVTVAAVVLIVA 199

Query: 163 AGLVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDS 222
             +   LL    L Y    C         D   ++  +  P    + L+   ++L P   
Sbjct: 200 VFVCKSLLWKKVLPYLKGICSGGG----GDPERVDRSSQRPGAEDNVLNEIVSILQPTQV 255

Query: 223 SEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAM 282
            E+   VQ       P  P     L P  +    + P+ A        L P +  G P  
Sbjct: 256 PEQEMEVQ------EPAEPTGVNMLSPGESEHLLE-PAEAERSQRRRLLVPANE-GDPTE 307

Query: 283 MLQPGPQLYD-VMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQ 339
            L+   Q +D   D VP   W+  +R LGL + EI+  + E    RD  Y ML +W  + 
Sbjct: 308 TLR---QCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKT 364

Query: 340 QQPAGLGAVYAALERMG 356
            + A +  +  ALE +G
Sbjct: 365 GRDASVHTLLDALETLG 381


>gi|23238204 tumor necrosis factor receptor superfamily, member 19
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 18/34 (52%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 93  CQPCLDCGALHRHTRLLCS-RRDTDCGTCLPGFY 125
           C+PCLDC  ++R  +  CS   D  CG CLPGFY
Sbjct: 89  CKPCLDCAVVNRFQKANCSATSDAICGDCLPGFY 122



 Score = 33.5 bits (75), Expect = 0.32
 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 4/52 (7%)

Query: 48  CRGCPAASQVALENCSAVADTRCG-CKPGWFVECQVSQCVSSSPFYCQPCLD 98
           C  C   ++    NCSA +D  CG C PG++   + ++ V      C PC D
Sbjct: 92  CLDCAVVNRFQKANCSATSDAICGDCLPGFY---RKTKLVGFQDMECVPCGD 140


>gi|23238202 tumor necrosis factor receptor superfamily, member 19
           isoform 1 precursor [Homo sapiens]
          Length = 423

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 18/34 (52%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 93  CQPCLDCGALHRHTRLLCS-RRDTDCGTCLPGFY 125
           C+PCLDC  ++R  +  CS   D  CG CLPGFY
Sbjct: 89  CKPCLDCAVVNRFQKANCSATSDAICGDCLPGFY 122



 Score = 33.5 bits (75), Expect = 0.32
 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 4/52 (7%)

Query: 48  CRGCPAASQVALENCSAVADTRCG-CKPGWFVECQVSQCVSSSPFYCQPCLD 98
           C  C   ++    NCSA +D  CG C PG++   + ++ V      C PC D
Sbjct: 92  CLDCAVVNRFQKANCSATSDAICGDCLPGFY---RKTKLVGFQDMECVPCGD 140


>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
           [Homo sapiens]
          Length = 468

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 81/302 (26%), Positives = 109/302 (36%), Gaps = 57/302 (18%)

Query: 87  SSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPERC 146
           S++ F C PC  C +         + R+T C  C PG + + +    C   + G CP   
Sbjct: 158 SNNLFACLPCTACKSDEEERSPCTTTRNTAC-QCKPGTFRNDNSAEMCRKCSRG-CPRGM 215

Query: 147 AAV---------------CGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTA 191
             V                G     WV +L+  LVVPLLL A L      C         
Sbjct: 216 VKVKDCTPWSDIECVHKESGNGHNIWV-ILVVTLVVPLLLVAVLIV----CCCIGSGCGG 270

Query: 192 DEAGME--------ALTPPPATHLSPLDSAHT-LLAPPDSSEKICTVQLVGNSWTPGYPE 242
           D   M+         L  P A      D+AH  +L+  DS     + Q +         E
Sbjct: 271 DPKCMDRVCFWRLGLLRGPGAE-----DNAHNEILSNADSLSTFVSEQQM---------E 316

Query: 243 TQEALCPQVTWSWDQLPSRA---LGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMD---- 295
           +QE     +T    Q P  A   LGPA A   S       PA    P   L    D    
Sbjct: 317 SQEP--ADLTGVTVQSPGEAQCLLGPAEAEG-SQRRRLLVPANGADPTETLMLFFDKFAN 373

Query: 296 AVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQPAGLGAVYAALE 353
            VP   W + +R L L + EI+ V        D  Y ML +W  +  + A +  +  ALE
Sbjct: 374 IVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTGRNASIHTLLDALE 433

Query: 354 RM 355
           RM
Sbjct: 434 RM 435


>gi|23200041 tumor necrosis factor receptor superfamily, member 14
           precursor [Homo sapiens]
          Length = 283

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 37/139 (26%), Positives = 53/139 (38%), Gaps = 26/139 (18%)

Query: 48  CRGC-PAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHT 106
           C+ C PA    A  NCS   +  CGC PG F       C+     +C  C          
Sbjct: 96  CQMCDPAMGLRASRNCSRTENAVCGCSPGHF-------CIVQDGDHCAACRAYATSSPGQ 148

Query: 107 RLL---CSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPE--RCA-----AVCGWRQMF 156
           R+       +DT C  C PG +         P  TL  C    +C+     A  G     
Sbjct: 149 RVQKGGTESQDTLCQNCPPGTFS--------PNGTLEECQHQTKCSWLVTKAGAGTSSSH 200

Query: 157 WVQVLLAGLVVPLLLGATL 175
           WV   L+G +V +++ +T+
Sbjct: 201 WVWWFLSGSLVIVIVCSTV 219


>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
          Length = 1140

 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 38/138 (27%), Positives = 51/138 (36%), Gaps = 27/138 (19%)

Query: 25  QGGTRSPRCDCAGDFHKKIGLFCCRGCPAASQVALENCSAVADTRCGCKPGWFVECQVSQ 84
           + G    RC+         G+ C + CP   +    +C  ++   C CKPGW        
Sbjct: 342 EAGFAGERCEARLCPEGLYGIKCDKRCPCHLENT-HSCHPMSG-ECACKPGW-------- 391

Query: 85  CVSSSPFYCQPCLDCGALHRHTRLLCS-RRDTDCG------TCLPGFYEHGDGCVSCPTS 137
               S  YC      G      + +CS +   DC       TC PGF +  D    CP  
Sbjct: 392 ----SGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGF-KGIDCSTPCPLG 446

Query: 138 TLG-SCPERCA----AVC 150
           T G +C  RC     AVC
Sbjct: 447 TYGINCSSRCGCKNDAVC 464



 Score = 32.0 bits (71), Expect = 0.92
 Identities = 39/141 (27%), Positives = 50/141 (35%), Gaps = 38/141 (26%)

Query: 27  GTRSP---RCDCAGDFHKKIGLFCCRGCPAA----SQVALENCSAVA-----DTRCGCKP 74
           GT +P    C C   +   IG  C + CP A    + +   NC   A     D  C C P
Sbjct: 679 GTCNPIDRSCQCYPGW---IGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTP 735

Query: 75  GWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCS-RRDTDCG------TCLPGFYEH 127
           GW            +  YC      G   +   L+C  +   DC       TC  GF   
Sbjct: 736 GW------------TGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFM-- 781

Query: 128 GDGC-VSCPTSTLG-SCPERC 146
           G  C   CP+ T G  C + C
Sbjct: 782 GRHCEQKCPSGTYGYGCRQIC 802



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 7/54 (12%)

Query: 103 HRHTRLLCSRRDTDCGTCLPGFYEHGDGCV-SCPTSTL-GSC--PERCAAVCGW 152
           +RH      RR + C    PGFYE G+ CV  C    + G C  P  C    GW
Sbjct: 80  YRHGEKTMYRRKSQC---CPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGW 130


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 49/162 (30%), Positives = 63/162 (38%), Gaps = 39/162 (24%)

Query: 163  AGLVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLD----SAHTLLA 218
            A L+VP L GA          P     + D+    A+ PP  ++L PLD    SA     
Sbjct: 1896 AELLVPSLEGAL---------PPDLDTSEDQQATAAIIPPEPSYLEPLDEGPFSAVITEE 1946

Query: 219  PPD---SSEKICTVQLVGN------SWTPG----------YPETQEALCPQVTWSWDQLP 259
            P +    SE+     L+G       SW  G          +PE+ +  CP      D L 
Sbjct: 1947 PVEWAHPSEQALASSLIGGTSENPVSWPVGSDLLLKSPQRFPESPKRFCPA-----DPLH 2001

Query: 260  SRALGPAAAPTLSPESPAGSPAMMLQP--GPQLYDVMDAVPA 299
            S A GP +A      +P  SPA    P   P L DV D V A
Sbjct: 2002 SAAPGPFSASEAPYPAPPASPAPYALPVAEPGLEDVKDGVDA 2043


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 27/97 (27%), Positives = 38/97 (39%), Gaps = 20/97 (20%)

Query: 53   AASQVALENCSAVADTRCGCKPGW---FVECQVSQCVSSSPFYCQPCLDCGALHRHT--- 106
            A++         +A  RC C PG+   F E ++  C      Y  PC + GA  R     
Sbjct: 1404 ASASTLFRPIQPIAGLRCRCPPGFTGDFCETELDLC------YSNPCRNGGACARREGGY 1457

Query: 107  RLLCSRR--------DTDCGTCLPGFYEHGDGCVSCP 135
              +C  R        DT+ G C+PG   +G  C   P
Sbjct: 1458 TCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTDAP 1494


>gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]
          Length = 1805

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 37/143 (25%), Positives = 55/143 (38%), Gaps = 17/143 (11%)

Query: 25  QGGTRSPRCDCAGDFHKKIGLFCCRG---CPAASQVALENCSAVADTRCGCKPGW---FV 78
           +G  +   C C G+   + G FC      CP  S     +    +  +C C+PGW     
Sbjct: 515 RGECQCGHCVCYGEGRYE-GQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC 573

Query: 79  ECQVSQ--CVSSSPFYC--QPCLDCGALHRHTRLLCSRRDTDC----GTCLPGFYEHGDG 130
           +C +S   C+ S+   C  +   +CG  H H + L +  DT C        PG  E    
Sbjct: 574 DCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYT--DTICEINYSAIHPGLCEDLRS 631

Query: 131 CVSCPTSTLGSCPERCAAVCGWR 153
           CV C     G    R    C ++
Sbjct: 632 CVQCQAWGTGEKKGRTCEECNFK 654


>gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]
          Length = 1822

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 37/143 (25%), Positives = 55/143 (38%), Gaps = 17/143 (11%)

Query: 25  QGGTRSPRCDCAGDFHKKIGLFCCRG---CPAASQVALENCSAVADTRCGCKPGW---FV 78
           +G  +   C C G+   + G FC      CP  S     +    +  +C C+PGW     
Sbjct: 515 RGECQCGHCVCYGEGRYE-GQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC 573

Query: 79  ECQVSQ--CVSSSPFYC--QPCLDCGALHRHTRLLCSRRDTDC----GTCLPGFYEHGDG 130
           +C +S   C+ S+   C  +   +CG  H H + L +  DT C        PG  E    
Sbjct: 574 DCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYT--DTICEINYSAIHPGLCEDLRS 631

Query: 131 CVSCPTSTLGSCPERCAAVCGWR 153
           CV C     G    R    C ++
Sbjct: 632 CVQCQAWGTGEKKGRTCEECNFK 654


>gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]
          Length = 1752

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 37/143 (25%), Positives = 55/143 (38%), Gaps = 17/143 (11%)

Query: 25  QGGTRSPRCDCAGDFHKKIGLFCCRG---CPAASQVALENCSAVADTRCGCKPGW---FV 78
           +G  +   C C G+   + G FC      CP  S     +    +  +C C+PGW     
Sbjct: 515 RGECQCGHCVCYGEGRYE-GQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC 573

Query: 79  ECQVSQ--CVSSSPFYC--QPCLDCGALHRHTRLLCSRRDTDC----GTCLPGFYEHGDG 130
           +C +S   C+ S+   C  +   +CG  H H + L +  DT C        PG  E    
Sbjct: 574 DCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYT--DTICEINYSAIHPGLCEDLRS 631

Query: 131 CVSCPTSTLGSCPERCAAVCGWR 153
           CV C     G    R    C ++
Sbjct: 632 CVQCQAWGTGEKKGRTCEECNFK 654


>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
          Length = 1575

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 38/154 (24%)

Query: 27  GTRSPRCDCAGD--FHKKIGLFC----CRGCPAASQV---ALENCSAVAD--TRC----- 70
           G R  RC+   D  F   +GLF     C  C  +  V   A+ NC  ++    RC     
Sbjct: 780 GQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTT 839

Query: 71  -----GCKPGWFVECQVSQCVSSSPFYCQPC-----------LDCGALHRHTRLLCSRRD 114
                 C+ G++      +        C PC           + C  +      L     
Sbjct: 840 GDHCEHCQEGFYGSALAPRPADK----CMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTA 895

Query: 115 TDCGTCLPGFYE--HGDGCVSCPTSTLGSCPERC 146
            DC  C PGF++   G GC SC    LGS  ++C
Sbjct: 896 RDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQC 929



 Score = 32.7 bits (73), Expect = 0.54
 Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 14/66 (21%)

Query: 93  CQPCLDC---GALHRHT--RLLCSRRDT----DCGTCLPGFYEHGDG----CVSCPTSTL 139
           CQPC DC   G+LH        C+ + T     C  CLPGF+   +G    C   P  +L
Sbjct: 380 CQPC-DCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL 438

Query: 140 GSCPER 145
            +C  R
Sbjct: 439 DTCDPR 444



 Score = 32.3 bits (72), Expect = 0.70
 Identities = 33/114 (28%), Positives = 43/114 (37%), Gaps = 19/114 (16%)

Query: 52  PAASQVALENC-SAVADTRC-GCKPGWFVECQVSQCVSSSPFYCQPCL--DCGALHRHTR 107
           P AS V + +C +      C  C PG+  E       +S    C PC     G    +T 
Sbjct: 665 PPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYAS----CVPCTCNQHGTCDPNTG 720

Query: 108 LLCSRRDTD---CGTCLPGFYEH-----GDGCVSCPTSTLGSC---PERCAAVC 150
           +      T+   C  CLPGFY +      D C  CP     +C   PE    VC
Sbjct: 721 ICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVC 774


>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
          Length = 1798

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 34/131 (25%), Positives = 48/131 (36%), Gaps = 19/131 (14%)

Query: 27  GTRSPRCDCAGDFHKKIGLFCCRGCPAASQVALENCSAVADTRCGCKPGWF-VECQVSQC 85
           G    RCD     +   G   C+ C  + + AL +       +C C+ G F + C   Q 
Sbjct: 807 GVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQR 866

Query: 86  VSSSPFYCQPCLDCG---ALHRHTRLLCSRRD----TDCGTCLPGFY-----EHGDGCVS 133
                  C+PC+  G     + HT      RD      C  C+ GF+      +G  C  
Sbjct: 867 GQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRP 926

Query: 134 CPTSTLGSCPE 144
           CP      CPE
Sbjct: 927 CP------CPE 931


>gi|4507579 tumor necrosis factor receptor superfamily, member 4
           precursor [Homo sapiens]
          Length = 277

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 45/167 (26%), Positives = 59/167 (35%), Gaps = 43/167 (25%)

Query: 13  AALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAASQVALENCSAVADTRCG- 71
           AALLL+ LG     G       C GD +      CC  C   + + +  CS   +T C  
Sbjct: 14  AALLLLGLGLSTVTGLH-----CVGDTYPSNDR-CCHECRPGNGM-VSRCSRSQNTVCRP 66

Query: 72  CKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTR--LLCSRRDT-------------- 115
           C PG++     +  VSS P  C+PC  C       R  L  + +DT              
Sbjct: 67  CGPGFY-----NDVVSSKP--CKPCTWCNLRSGSERKQLCTATQDTVCRCRAGTQPLDSY 119

Query: 116 ----DCGTCLPGFYEHGD--------GCVSCPTSTLGSCPERCAAVC 150
               DC  C PG +  GD         C      TL        A+C
Sbjct: 120 KPGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSSDAIC 166


>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
          Length = 1609

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 39/152 (25%), Positives = 54/152 (35%), Gaps = 34/152 (22%)

Query: 27  GTRSPRCDCAGD--FHKKIG----LFCCRGCPAASQV---ALENCSAVADT--RC----- 70
           GT   RC+   D  F   +G    +  CR C  +  +   A+ NC+ +     +C     
Sbjct: 798 GTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTA 857

Query: 71  -----GCKPGWFV---------ECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTD 116
                 CK G+F          +C+   C        Q    C  +      L      D
Sbjct: 858 GFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQS--SCNPVTGQCECLPHVTGQD 915

Query: 117 CGTCLPGFY--EHGDGCVSCPTSTLGSCPERC 146
           CG C PGFY  + G GC  C    LGS   +C
Sbjct: 916 CGACDPGFYNLQSGQGCERCDCHALGSTNGQC 947


>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
          Length = 1044

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 33/135 (24%)

Query: 27  GTRSPRCD---CAGDFHKKIGLFCCRGCPAASQVALENCSAVADTRCGCKPGWFVECQVS 83
           G + PRC    C    H   G  C   CP  +   + +C  V    C C+PGW       
Sbjct: 338 GYKGPRCQERLCPEGLH---GPGCTLPCPCDADNTI-SCHPVTGA-CTCQPGW------- 385

Query: 84  QCVSSSPFYCQPCLDCGALHRHTRLLCS-RRDTDCG------TCLPGFYEHGDGC-VSCP 135
                S  +C      G      +L C+ +   DC       TC PGF   G+ C VSC 
Sbjct: 386 -----SGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFM--GEVCAVSCA 438

Query: 136 TSTLGSCPERCAAVC 150
             T G     C+++C
Sbjct: 439 AGTYG---PNCSSIC 450



 Score = 37.0 bits (84), Expect = 0.029
 Identities = 36/117 (30%), Positives = 42/117 (35%), Gaps = 16/117 (13%)

Query: 44  GLFCCRGCPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVS-------SSPFYCQPC 96
           GL C   C  A+  A   CS + D  C C PGW  +     C         S    C   
Sbjct: 486 GLNCNESCTCANGAA---CSPI-DGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHA 541

Query: 97  LDCGALHRHTRLLCSRRDTDC-GTCLPGFYEHGDGC-VSCPTSTLGSC-PERCAAVC 150
             C  +  H   L       C  TC PG +  G  C VSC     GSC PE  +  C
Sbjct: 542 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRW--GPNCSVSCSCENGGSCSPEDGSCEC 596



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 36/119 (30%), Positives = 46/119 (38%), Gaps = 22/119 (18%)

Query: 35  CAGDFHKKIGLFCCRGCPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSP--FY 92
           CAG +    G  C + C  A+      CS + D  C C PGW  +     C  + P  F+
Sbjct: 654 CAGGY---FGQDCAQLCSCANN---GTCSPI-DGSCQCFPGWIGK----DCSQACPPGFW 702

Query: 93  CQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVS-CPTSTLGSCPERCAAVC 150
              C    A   H    CS  D  C  C PG+   G  C   CP +  G   + C  VC
Sbjct: 703 GPACFH--ACSCHNGASCSAEDGAC-HCTPGW--TGLFCTQRCPAAFFG---KDCGRVC 753



 Score = 33.1 bits (74), Expect = 0.41
 Identities = 40/138 (28%), Positives = 52/138 (37%), Gaps = 37/138 (26%)

Query: 24  AQGGTRSP---RCDCAGDFHKKIGLFCCRGCP----------AASQVALENCSAVADTRC 70
           A  GT SP    C C   F   IG  C + CP          A S     +CSA  D  C
Sbjct: 670 ANNGTCSPIDGSCQC---FPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSA-EDGAC 725

Query: 71  GCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDG 130
            C PGW       +C ++  F+ +   DCG      R+   +    C        +H  G
Sbjct: 726 HCTPGWTGLFCTQRCPAA--FFGK---DCG------RVCQCQNGASC--------DHISG 766

Query: 131 CVSCPTSTLGS-CPERCA 147
             +C T   G  C +RCA
Sbjct: 767 KCTCRTGFTGQHCEQRCA 784



 Score = 32.0 bits (71), Expect = 0.92
 Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 8/56 (14%)

Query: 101 ALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTL--GSC--PERCAAVCGW 152
           A  R  R +  RR      C PG+YE GD C+   T     G C  P+ C    GW
Sbjct: 73  AYRRGLRTMYRRRSQ----CCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGW 124



 Score = 28.9 bits (63), Expect = 7.8
 Identities = 35/131 (26%), Positives = 46/131 (35%), Gaps = 25/131 (19%)

Query: 29  RSPRCDCAGDFHKKIGLFCCRGCPAASQVA-------LEN---CSAVADTRCGCKPGWFV 78
           R+  C CA  +    G++C   CP  S  A        +N   C  +    C C PGW  
Sbjct: 200 RAGECLCAPGY---TGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITG-ECACPPGWTG 255

Query: 79  ECQVSQCVSSSPFYCQPC-LDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGC-VSCPT 136
                 C   +  + Q C  DC   H      C      C  C  G+   GD C   CP 
Sbjct: 256 AVCAQPCPPGT--FGQNCSQDCPCHHGGQ---CDHVTGQC-HCTAGYM--GDRCQEECPF 307

Query: 137 STLG-SCPERC 146
            + G  C + C
Sbjct: 308 GSFGFQCSQHC 318


>gi|219842266 usherin isoform B [Homo sapiens]
          Length = 5202

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 31/125 (24%), Positives = 45/125 (36%), Gaps = 11/125 (8%)

Query: 33  CDCAGDFHKKIGLFCCRG---CPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSS 89
           CD  G  +    L C +    CP    V    C+     R       F  CQ+ +C S  
Sbjct: 849 CDKTGTINGS--LLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLG 906

Query: 90  PFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFY---EHGDGCVSCPTSTLGSCPERC 146
                P   C  +      + +R+   C  C PGFY    +  GC+ C   T G+    C
Sbjct: 907 TL---PGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHIC 963

Query: 147 AAVCG 151
            ++ G
Sbjct: 964 NSLTG 968


>gi|219842259 usherin isoform A [Homo sapiens]
          Length = 1546

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 31/125 (24%), Positives = 45/125 (36%), Gaps = 11/125 (8%)

Query: 33  CDCAGDFHKKIGLFCCRG---CPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSS 89
           CD  G  +    L C +    CP    V    C+     R       F  CQ+ +C S  
Sbjct: 849 CDKTGTINGS--LLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLG 906

Query: 90  PFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFY---EHGDGCVSCPTSTLGSCPERC 146
                P   C  +      + +R+   C  C PGFY    +  GC+ C   T G+    C
Sbjct: 907 TL---PGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHIC 963

Query: 147 AAVCG 151
            ++ G
Sbjct: 964 NSLTG 968


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 27/121 (22%), Positives = 47/121 (38%), Gaps = 8/121 (6%)

Query: 32   RCDCAGDFHKKIGLFCCRGCPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPF 91
            +C C  +++K +    C  C      +      +A  +C CKPG  +  Q ++C   +PF
Sbjct: 1984 QCQCKENYYKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKPG-VIGRQCNRC--DNPF 2040

Query: 92   YCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPERCAAVCG 151
                 L C  ++      C +   + G   P         V CP  ++G+    C+   G
Sbjct: 2041 AEVTTLGCEVIYNG----CPKA-FEAGIWWPQTKFGQPAAVPCPKGSVGNAVRHCSGEKG 2095

Query: 152  W 152
            W
Sbjct: 2096 W 2096


>gi|33598931 scavenger receptor class F, member 1 isoform 3
           precursor [Homo sapiens]
          Length = 569

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 45/135 (33%), Positives = 53/135 (39%), Gaps = 23/135 (17%)

Query: 32  RCDCA-GDFHKKIGLFC--CRGCPAASQVALENCSAVADTRCGCKPGWF-------VECQ 81
           RCD A G  H + G +   CR  P     A   C   A   C CKPGW+         C 
Sbjct: 140 RCDPATGVCHCEPGWWSSTCRR-PCQCNTAAARCEQ-ATGACVCKPGWWGRRCSFRCNCH 197

Query: 82  VSQC-VSSSPFYCQPCL---DCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGC-VSCPT 136
            S C   S    C+P     +C       R  CS    +C TC PGF   G  C + CP 
Sbjct: 198 GSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGEC-TCPPGF--RGARCELPCPA 254

Query: 137 STLGSCPERCAAVCG 151
              GS   +CA  CG
Sbjct: 255 ---GSHGVQCAHSCG 266


>gi|33598929 scavenger receptor class F, member 1 isoform 1
           precursor [Homo sapiens]
          Length = 830

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 45/135 (33%), Positives = 53/135 (39%), Gaps = 23/135 (17%)

Query: 32  RCDCA-GDFHKKIGLFC--CRGCPAASQVALENCSAVADTRCGCKPGWF-------VECQ 81
           RCD A G  H + G +   CR  P     A   C   A   C CKPGW+         C 
Sbjct: 140 RCDPATGVCHCEPGWWSSTCRR-PCQCNTAAARCEQ-ATGACVCKPGWWGRRCSFRCNCH 197

Query: 82  VSQC-VSSSPFYCQPCL---DCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGC-VSCPT 136
            S C   S    C+P     +C       R  CS    +C TC PGF   G  C + CP 
Sbjct: 198 GSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGEC-TCPPGF--RGARCELPCPA 254

Query: 137 STLGSCPERCAAVCG 151
              GS   +CA  CG
Sbjct: 255 ---GSHGVQCAHSCG 266


>gi|145309306 scavenger receptor class F, member 1 isoform 5
           precursor [Homo sapiens]
          Length = 744

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 45/135 (33%), Positives = 53/135 (39%), Gaps = 23/135 (17%)

Query: 32  RCDCA-GDFHKKIGLFC--CRGCPAASQVALENCSAVADTRCGCKPGWF-------VECQ 81
           RCD A G  H + G +   CR  P     A   C   A   C CKPGW+         C 
Sbjct: 140 RCDPATGVCHCEPGWWSSTCRR-PCQCNTAAARCEQ-ATGACVCKPGWWGRRCSFRCNCH 197

Query: 82  VSQC-VSSSPFYCQPCL---DCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGC-VSCPT 136
            S C   S    C+P     +C       R  CS    +C TC PGF   G  C + CP 
Sbjct: 198 GSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGEC-TCPPGF--RGARCELPCPA 254

Query: 137 STLGSCPERCAAVCG 151
              GS   +CA  CG
Sbjct: 255 ---GSHGVQCAHSCG 266


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.462 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,975,570
Number of Sequences: 37866
Number of extensions: 989085
Number of successful extensions: 4542
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 166
Number of HSP's that attempted gapping in prelim test: 4235
Number of HSP's gapped (non-prelim): 466
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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