Search of human proteins with 21314684

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21314684 single stranded DNA binding protein 3 isoform b
[Homo sapiens]
         (368 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21314684 single stranded DNA binding protein 3 isoform b [Hom...   802   0.0  
gi|21955170 single stranded DNA binding protein 3 isoform a [Hom...   790   0.0  
gi|58218981 single stranded DNA binding protein 3 isoform c [Hom...   736   0.0  
gi|40787999 single-stranded DNA binding protein 2 [Homo sapiens]      612   e-175
gi|14249150 single stranded DNA binding protein 4 isoform a [Hom...   565   e-161
gi|58218984 single stranded DNA binding protein 4 isoform b [Hom...   541   e-154
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     99   6e-21
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    91   2e-18
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      89   8e-18
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    84   2e-16
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                83   3e-16
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      81   1e-15
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    79   5e-15
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    79   5e-15
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    79   5e-15
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    79   5e-15
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           79   5e-15
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    79   6e-15
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    79   6e-15
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    79   8e-15
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    79   8e-15
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                   78   1e-14
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 78   1e-14
gi|23510333 pygopus homolog 2 [Homo sapiens]                           76   4e-14
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       75   7e-14
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       75   9e-14
gi|160707881 formin 2 [Homo sapiens]                                   75   9e-14
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    75   9e-14
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    75   9e-14
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    75   9e-14

>gi|21314684 single stranded DNA binding protein 3 isoform b [Homo
           sapiens]
          Length = 368

 Score =  802 bits (2072), Expect = 0.0
 Identities = 368/368 (100%), Positives = 368/368 (100%)

Query: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60
           MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH
Sbjct: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60

Query: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120
           SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF
Sbjct: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120

Query: 121 FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSM 180
           FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSM
Sbjct: 121 FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSM 180

Query: 181 QRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSS 240
           QRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSS
Sbjct: 181 QRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSS 240

Query: 241 SSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 300
           SSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM
Sbjct: 241 SSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 300

Query: 301 GGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNY 360
           GGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNY
Sbjct: 301 GGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNY 360

Query: 361 SPSMTMSV 368
           SPSMTMSV
Sbjct: 361 SPSMTMSV 368


>gi|21955170 single stranded DNA binding protein 3 isoform a [Homo
           sapiens]
          Length = 388

 Score =  790 bits (2041), Expect = 0.0
 Identities = 368/388 (94%), Positives = 368/388 (94%), Gaps = 20/388 (5%)

Query: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60
           MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH
Sbjct: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60

Query: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120
           SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF
Sbjct: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120

Query: 121 FQGPPGSQPSPHAQPPPHNPSSMMGPHSQP--------------------PGGVPGTQPL 160
           FQGPPGSQPSPHAQPPPHNPSSMMGPHSQP                    PGGVPGTQPL
Sbjct: 121 FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPL 180

Query: 161 LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG 220
           LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG
Sbjct: 181 LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG 240

Query: 221 PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP 280
           PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP
Sbjct: 241 PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP 300

Query: 281 VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 340
           VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT
Sbjct: 301 VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 360

Query: 341 PRDDGELGGNFLHSFQNDNYSPSMTMSV 368
           PRDDGELGGNFLHSFQNDNYSPSMTMSV
Sbjct: 361 PRDDGELGGNFLHSFQNDNYSPSMTMSV 388


>gi|58218981 single stranded DNA binding protein 3 isoform c [Homo
           sapiens]
          Length = 361

 Score =  736 bits (1901), Expect = 0.0
 Identities = 348/368 (94%), Positives = 349/368 (94%), Gaps = 7/368 (1%)

Query: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60
           MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH
Sbjct: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60

Query: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120
           SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF
Sbjct: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120

Query: 121 FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSM 180
           FQ  P   P     P    P   MG  +QPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSM
Sbjct: 121 FQ--PFMSPRYAGGP---RPPIRMG--NQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSM 173

Query: 181 QRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSS 240
           QRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSS
Sbjct: 174 QRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSS 233

Query: 241 SSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 300
           SSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM
Sbjct: 234 SSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 293

Query: 301 GGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNY 360
           GGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNY
Sbjct: 294 GGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNY 353

Query: 361 SPSMTMSV 368
           SPSMTMSV
Sbjct: 354 SPSMTMSV 361


>gi|40787999 single-stranded DNA binding protein 2 [Homo sapiens]
          Length = 361

 Score =  612 bits (1579), Expect = e-175
 Identities = 292/372 (78%), Positives = 318/372 (85%), Gaps = 15/372 (4%)

Query: 1   MFAKGKG--SAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGF 58
           M+ KGK   SAVPSD QAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGF
Sbjct: 1   MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGF 60

Query: 59  LHSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPP 118
           LHSWWCVFWDLYCAAPERR+TCEHSSEAKAFHDYSAAAAPSPVLGNIPP DGMP GP+PP
Sbjct: 61  LHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPP 120

Query: 119 GFFQGPPGSQPSPHAQPP-PHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMG 177
           GFFQ        P   P  P  P   +   +Q  GGVPG+QPLLP+ MDPTRQQGHPNMG
Sbjct: 121 GFFQ--------PFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMG 172

Query: 178 GSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL-GPAMPGINMGPGAGRPWPNPNSANSI 236
           G MQRM PPRGM P+  GPQNYG  MRPP N+L GP MPG+NMGPG GRPWPNP +ANSI
Sbjct: 173 GPMQRMTPPRGMVPL--GPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSI 230

Query: 237 PYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGS 296
           PYSS+SPG YVGPPGGGGPPGTPIMPSPADSTNS DN+YT++N VPPG +R NFPMGPGS
Sbjct: 231 PYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGS 290

Query: 297 DGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQ 356
           DGPMGG+GGME HHMNGSLGSGD+D + KNSPNN+S +SN PGTPRDDGE+GGNFL+ FQ
Sbjct: 291 DGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMS-LSNQPGTPRDDGEMGGNFLNPFQ 349

Query: 357 NDNYSPSMTMSV 368
           +++YSPSMTMSV
Sbjct: 350 SESYSPSMTMSV 361


>gi|14249150 single stranded DNA binding protein 4 isoform a [Homo
           sapiens]
          Length = 385

 Score =  565 bits (1457), Expect = e-161
 Identities = 272/394 (69%), Positives = 313/394 (79%), Gaps = 35/394 (8%)

Query: 1   MFAKG-KGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFL 59
           M+AKG KGSAVPSD QAREKLALYVYEYLLH+GAQKSAQTFLSEIRWEKNITLGEPPGFL
Sbjct: 1   MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL 60

Query: 60  HSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPG 119
           HSWWCVFWDLYCAAP+RR+ CEHS EAKAF DYSAAAAPSPV+G++ P D M  G +  G
Sbjct: 61  HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG 120

Query: 120 FFQGPPGSQPSPHAQPPPHNPSS-MMGPH--------------------SQPPGGVPGTQ 158
           FFQGPPGSQPS      PHNP++ MMGPH                    SQPP G+PG+Q
Sbjct: 121 FFQGPPGSQPS------PHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQ 174

Query: 159 PLLPNSMDPT-RQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL-GPAMPG 216
           PLLP +M+P+ R QGHP+MGG MQR+ PPRGM  +  GPQ+YG GMRPPPNSL GP +P 
Sbjct: 175 PLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASV--GPQSYGGGMRPPPNSLAGPGLPA 232

Query: 217 INMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYT 276
           +NMGPG   PW +P S NSIPYSSSSPG+Y GPPGGGGPPGTPIMPSP DSTNSS+N+YT
Sbjct: 233 MNMGPGVRGPWASP-SGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYT 291

Query: 277 MINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISN 336
           ++NP+  G  R+NFP+GPG +GPM  M  MEPHH+NGSLGSGD+DGLPK+SP  ++G+SN
Sbjct: 292 IMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSN 351

Query: 337 PPGTPRDDGEL--GGNFLHSFQNDNYSPSMTMSV 368
            PGTPRDDGE+   G FLH F +++YSP MTMSV
Sbjct: 352 APGTPRDDGEMAAAGTFLHPFPSESYSPGMTMSV 385


>gi|58218984 single stranded DNA binding protein 4 isoform b [Homo
           sapiens]
          Length = 363

 Score =  541 bits (1394), Expect = e-154
 Identities = 259/374 (69%), Positives = 299/374 (79%), Gaps = 17/374 (4%)

Query: 1   MFAKG-KGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFL 59
           M+AKG KGSAVPSD QAREKLALYVYEYLLH+GAQKSAQTFLSEIRWEKNITLGEPPGFL
Sbjct: 1   MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL 60

Query: 60  HSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPG 119
           HSWWCVFWDLYCAAP+RR+ CEHS EAKAF DYSAAAAPSPV+G++ P D M  G +  G
Sbjct: 61  HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG 120

Query: 120 FFQGPPGSQPSPHAQPP-PHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPT-RQQGHPNMG 177
           FFQ        P   P  P  P   +   SQPP G+PG+QPLLP +M+P+ R QGHP+MG
Sbjct: 121 FFQ--------PFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMG 172

Query: 178 GSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL-GPAMPGINMGPGAGRPWPNPNSANSI 236
           G MQR+ PPRGM  +  GPQ+YG GMRPPPNSL GP +P +NMGPG   PW +P S NSI
Sbjct: 173 GPMQRVTPPRGMASV--GPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASP-SGNSI 229

Query: 237 PYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGS 296
           PYSSSSPG+Y GPPGGGGPPGTPIMPSP DSTNSS+N+YT++NP+  G  R+NFP+GPG 
Sbjct: 230 PYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGP 289

Query: 297 DGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGEL--GGNFLHS 354
           +GPM  M  MEPHH+NGSLGSGD+DGLPK+SP  ++G+SN PGTPRDDGE+   G FLH 
Sbjct: 290 EGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHP 349

Query: 355 FQNDNYSPSMTMSV 368
           F +++YSP MTMSV
Sbjct: 350 FPSESYSPGMTMSV 363


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 99.0 bits (245), Expect = 6e-21
 Identities = 97/303 (32%), Positives = 108/303 (35%), Gaps = 38/303 (12%)

Query: 83  SSEAKAFHDYSAAAAPSPVLGN---IPPNDGMP--GGPIPPGFFQGPP---GSQPSPHAQ 134
           SS      D S   +PS + GN    PP  G    G P PPG  QGPP   G+QP     
Sbjct: 14  SSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP 73

Query: 135 PP--PHNPSSMMG--PHSQPPGGVP------GTQPLLPNSMDPTRQQGHPNMGGSMQRMN 184
           PP  P  P    G  P   PP G P      G +   P S  P + QG P  GG+  +  
Sbjct: 74  PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS-PPGKPQGPPPQGGNQPQGP 132

Query: 185 PPRGMGPMGPGPQ--NYGSGMRPPPNSLGPAMPGINMGPGAGRP-----WPNPNSANSIP 237
           PP    P GP PQ  N   G  PP    GP   G N    +  P      P P   N   
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ 192

Query: 238 YSSSSPGTYVGPPGGGG-------PPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNF 290
                PG   GPP  GG       PPG P  P P     S         P  P     N 
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ 252

Query: 291 PMGPGSDGPMGGMGGMEPHHMNGSLG---SGDIDGLPKNSPNNISGISNPPGTPRDDGEL 347
           P GP    P G   G  P   N   G    G   G P    +      +PPG P+     
Sbjct: 253 PQGP--PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQ 310

Query: 348 GGN 350
           GGN
Sbjct: 311 GGN 313



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 69/226 (30%), Positives = 75/226 (33%), Gaps = 44/226 (19%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGFFQGPPG----------SQPSPHAQPPPHNPSSMMGPH 147
           P    G  P     P GP PPG  QGPP           S P     PPP   +   GP 
Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP- 256

Query: 148 SQPPGGVPGTQPLLPNSMD----PTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGM 203
             PPG   G  P   N       P + QG P  GGS  R +      P GP PQ      
Sbjct: 257 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQ 316

Query: 204 RPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGG--------P 255
            PPP       PG   GP        P    + P     PG   GPP  GG        P
Sbjct: 317 GPPP------PPGKPQGP--------PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP 362

Query: 256 PGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMG 301
           PG P  P   +  N          P PP G     P  P +  P G
Sbjct: 363 PGKPQGPPQQEGNNPQ-------GPPPPAGGNPQQPQAPPAGQPQG 401



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 59/168 (35%), Positives = 66/168 (39%), Gaps = 18/168 (10%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGFFQGPP--GSQPSPHAQPPPHNPSSMMGPHSQPPGGVP 155
           P    G  P     P GP PPG  QGPP  G   S  ++ PP  P    GP   PP G  
Sbjct: 260 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQ---GP---PPQG-- 311

Query: 156 GTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYG---SGMRPPPNSLGP 212
           G QP  P    P + QG P  GG+  +  PP G  P GP PQ      S   PP    GP
Sbjct: 312 GNQPQGPPP-PPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGGSKSRSARSPPGKPQGP 369

Query: 213 AMPGINMGPGAGRP-WPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTP 259
                N   G   P   NP    + P  +  P     PP GG P   P
Sbjct: 370 PQQEGNNPQGPPPPAGGNPQQPQAPP--AGQPQGPPRPPQGGRPSRPP 415



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 40/124 (32%), Positives = 45/124 (36%), Gaps = 14/124 (11%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGG-PIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPP 151
           S+ + P    G  P     P G P PPG  QGPP    +    PPP  P    GP   P 
Sbjct: 296 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP--PGKPQGP--PPQ 351

Query: 152 GG-------VPGTQPLLPNSMDPTRQQGHPNMGGS--MQRMNPPRGMGPMGPGPQNYGSG 202
           GG        P  +P  P   +    QG P   G    Q   PP G     P P   G  
Sbjct: 352 GGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 411

Query: 203 MRPP 206
            RPP
Sbjct: 412 SRPP 415


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 92/290 (31%), Positives = 104/290 (35%), Gaps = 35/290 (12%)

Query: 83  SSEAKAFHDYSAAAAPSPVLGN----IPPNDGMPGGPIPP-GFFQGPPGSQPSPHAQPPP 137
           SS      D S   +PS + GN     P     P GP PP G  QGPP    +    PPP
Sbjct: 14  SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP 73

Query: 138 HNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQ 197
             P    GP   PP G     P  P    P + QG P  GG+  +  PP    P GP PQ
Sbjct: 74  --PGKPQGP---PPQGDKSRSPRSP----PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 124

Query: 198 --NYGSGMRPPPNSLGPAMPGIN----MGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPG 251
             N   G  PP    GP   G        P      P P   N        PG   GPP 
Sbjct: 125 GGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 184

Query: 252 GGG-------PPGTPIMPSP-ADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGM 303
            GG       PPG P  P P  D + SS +        PP G   N P GP    P G  
Sbjct: 185 QGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG--GNQPQGP--PPPPGKP 240

Query: 304 GGMEPHHMNGSLG---SGDIDGLPKNSPNNISGISNPPGTPRDDGELGGN 350
            G  P   N   G    G   G P    +      +PPG P+   +  GN
Sbjct: 241 QGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN 290



 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 71/218 (32%), Positives = 78/218 (35%), Gaps = 30/218 (13%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGT 157
           P    G  P     P GP PPG  QGPP   P       P +P     P   PP G  G 
Sbjct: 115 PGKPQGPPPQGGNRPQGPPPPGKPQGPP---PQGDKSRSPRSPPGK--PQGPPPQG--GN 167

Query: 158 QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQN--YGSGMRPPPNSLGPAMP 215
           QP  P    P + QG P  GG   +  PP G  P GP PQ     S   PP    GP   
Sbjct: 168 QPQGPPP-PPGKPQGPPPQGGKKPQGPPPPGK-PQGPPPQGDKSRSSQSPPGKPQGPPPQ 225

Query: 216 GINMGPGA----GRPWPNPNSANSIPYSSSSPGTYVGPPGGGG--------PPGTPIMPS 263
           G N   G     G+P   P    + P     PG   GPP  GG        PPG P  P 
Sbjct: 226 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPP 285

Query: 264 PADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMG 301
             +  N          P PP G     P  P +  P G
Sbjct: 286 QQEGNNPQ-------GPPPPAGGNPQQPQAPPAGQPQG 316



 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 78/245 (31%), Positives = 85/245 (34%), Gaps = 43/245 (17%)

Query: 98  PSPVLGNIP---PNDGMPGGP-----------IPPGFFQGPP---GSQPSPHAQPP--PH 138
           P P  GN P   P  G P GP            PPG  QGPP   G+QP     PP  P 
Sbjct: 60  PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 119

Query: 139 NPSSMMG--PHSQPPGGVP------GTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMG 190
            P    G  P   PP G P      G +   P S  P + QG P  GG+  +  PP    
Sbjct: 120 GPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRS-PPGKPQGPPPQGGNQPQGPPPPPGK 178

Query: 191 PMGPGPQNYGSGMRPPP--NSLGPAMPG----INMGPGAGRPWPNPNSANSIPYSSSSPG 244
           P GP PQ       PPP     GP   G     +  P      P P   N        PG
Sbjct: 179 PQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG 238

Query: 245 TYVGPPGGGG-------PPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSD 297
              GPP  GG       PPG P  P     + S         P  P     N P GP   
Sbjct: 239 KPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP--P 296

Query: 298 GPMGG 302
            P GG
Sbjct: 297 PPAGG 301



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 41/121 (33%), Positives = 49/121 (40%), Gaps = 8/121 (6%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPP-GFFQGPPGSQPS-PHAQPPP---HNPSSMMGPH 147
           S+ + P    G  P     P GP PP G  QGPP    + P   PPP     P +  G  
Sbjct: 211 SSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK 270

Query: 148 SQPPGGVPGTQPLLPNSMDPTRQQGHPN-MGGSMQRMNPPRGMGPMG-PGPQNYGSGMRP 205
           SQ     PG +P  P   +    QG P   GG+ Q+   P    P G P P   G   RP
Sbjct: 271 SQSARSPPG-KPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329

Query: 206 P 206
           P
Sbjct: 330 P 330


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 88/291 (30%), Positives = 101/291 (34%), Gaps = 32/291 (10%)

Query: 96  AAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVP 155
           A P    G  P  DG+PGGP   G   G PG   S     PP +      P    P G P
Sbjct: 515 AGPRGAAGE-PGRDGVPGGPGMRGM-PGSPGGPGSDGKPGPPGSQGESGRPGPPGPSG-P 571

Query: 156 GTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLG---- 211
             QP +     P    G P   G       P G GP GP  +N  +G + PP   G    
Sbjct: 572 RGQPGVMGFPGPKGNDGAPGKNGER---GGPGGPGPQGPPGKNGETGPQGPPGPTGPGGD 628

Query: 212 ------PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPA 265
                 P   G+   PG G P P  N     P      G   G PGG G  G P    P 
Sbjct: 629 KGDTGPPGPQGLQGLPGTGGP-PGENGKPGEPGPKGDAGA-PGAPGGKGDAGAPGERGPP 686

Query: 266 DSTNSSDNIYTMINPVPPGGSRSNFPMGP----------GSDGPMGGMGGMEPHHMNGSL 315
               +         P P GG  +  P GP          G  G  GG+G   P    G  
Sbjct: 687 GLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEP 746

Query: 316 GSGDIDGLP-KNSPNNISGISNPP---GTPRDDGELGGNFLHSFQNDNYSP 362
           G    DG+P K+ P   +G   PP   G P D GE G   L        SP
Sbjct: 747 GGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSP 797



 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 83/281 (29%), Positives = 105/281 (37%), Gaps = 47/281 (16%)

Query: 105 IPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMM---------GPHSQP-PGGV 154
           IP   G PG P PPG  +  P    +   Q   ++  S +         GP   P P G 
Sbjct: 125 IPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP 184

Query: 155 PGTQ--PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLG- 211
           PGT   P  P S       G P   G      PP  +GP GP  ++  SG    P   G 
Sbjct: 185 PGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGL 244

Query: 212 PAMPGINMGPGAGRPW----------------------PNPNSANSIPYSSSSPGTYVGP 249
           P  PGI  GP AG P                       P     N +P  + +PG  +GP
Sbjct: 245 PGPPGIK-GP-AGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGP-MGP 301

Query: 250 PGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGG-SRSNFPMGPGSDGPMGGMGGMEP 308
            G  G  G P +P  A +  +     +   P PPG    + FP  PG+ G +G  G    
Sbjct: 302 RGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSP-- 359

Query: 309 HHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGG 349
               GS G+    G P   P   +G   PPG P  +G  GG
Sbjct: 360 ----GSNGAPGQRGEP--GPQGHAGAQGPPGPPGINGSPGG 394



 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 74/249 (29%), Positives = 87/249 (34%), Gaps = 24/249 (9%)

Query: 110  GMPGGPIPPGF-----FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNS 164
            G PGGP   GF       GPPGS  +P    P  +P     P      G PG+    P  
Sbjct: 864  GSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGS----PGV 919

Query: 165  MDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGP-AMPGINMGPG- 222
              P    G P   GS     PP   GP+G        G+  PP   GP   PG     G 
Sbjct: 920  SGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGE 979

Query: 223  AGRPWPNPNSA-NSIPYSSSSPGT--YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMIN 279
            +G+P  N  S     P     PG     G PG  G PG+  +P    S     +     +
Sbjct: 980  SGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGS 1039

Query: 280  PVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPG 339
            P  PG      P  PG  GP+G  G       +G  G     G     P    G   P G
Sbjct: 1040 PGAPGA-----PGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG-----PAGSRGAPGPQG 1089

Query: 340  TPRDDGELG 348
               D GE G
Sbjct: 1090 PRGDKGETG 1098



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 82/279 (29%), Positives = 96/279 (34%), Gaps = 63/279 (22%)

Query: 110 GMPGGPIPPGFF--------QGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLL 161
           G PG   PPG           GPPG +    A  PP  P +   P  Q   G+PG +  L
Sbjct: 678 GAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ---GMPGERGGL 734

Query: 162 PNSMDPTRQQGHPNMGGS--MQRMNPPRG----MGPMGPG--PQNYGSGMRP-------- 205
             S  P   +G P   G+  +   + PRG    +GP GP   P + G G  P        
Sbjct: 735 -GSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGP 793

Query: 206 -----------PPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGG 253
                      PP   G P  PG N  PG       P            P    GPPGG 
Sbjct: 794 RGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGE-----GGPPGVAGPPGGS 848

Query: 254 GPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNG 313
           GP G P  P        S          P G   + FP   G  GP G  G   P   +G
Sbjct: 849 GPAGPP-GPQGVKGERGS----------PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSG 897

Query: 314 SLGSGDIDGLPKNSPN----NISGISNPPGTPRDDGELG 348
           S G    DG P  + N       G+S P G     GE G
Sbjct: 898 SPGK---DGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG 933



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 74/259 (28%), Positives = 91/259 (35%), Gaps = 52/259 (20%)

Query: 108 NDGMPGGPIPPGF--FQGPPGSQ--------------PSPHAQPPPHNPSSMMGPHSQPP 151
           +DG PG P PPG   F G PG++              P    +P P   +   GP   PP
Sbjct: 328 SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPG-PP 386

Query: 152 G--GVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNS 209
           G  G PG +      M P    G P + G+          GP GP   N   G+R     
Sbjct: 387 GINGSPGGK----GEMGPAGIPGAPGLMGAR---------GPPGPAGANGAPGLRG---- 429

Query: 210 LGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTN 269
            G   PG N   G   P      A  IP    + G   G  G  G PG   +P  A    
Sbjct: 430 -GAGEPGKNGAKGEPGPRGERGEAG-IPGVPGAKGED-GKDGSPGEPGANGLPGAAGERG 486

Query: 270 SSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPN 329
           +         P  P G        PG  GP G  G   P    G+ G    DG+P     
Sbjct: 487 APG----FRGPAGPNGI-------PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP-- 533

Query: 330 NISGISNPPGTPRDDGELG 348
            + G+   PG P  DG+ G
Sbjct: 534 GMRGMPGSPGGPGSDGKPG 552



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 79/281 (28%), Positives = 91/281 (32%), Gaps = 54/281 (19%)

Query: 106  PPNDGMPGGPIPPGF--------FQGPPGSQPSPHAQPPPHNPSSMMGPHSQ-------- 149
            P   G PG P P G           GPPG  P P   P P       G            
Sbjct: 935  PGAQGPPGAPGPLGIAGITGARGLAGPPG-MPGPRGSPGPQGVKGESGKPGANGLSGERG 993

Query: 150  PPG--GVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-------------- 193
            PPG  G+PG   L   + +P R  G+P   G   R   P G G  G              
Sbjct: 994  PPGPQGLPG---LAGTAGEPGRD-GNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHP 1049

Query: 194  --PGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT--YVGP 249
              PGP    +G        GPA P    GP   R  P P         +   G     G 
Sbjct: 1050 GPPGPVG-PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGH 1108

Query: 250  PGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEP 308
             G  G PG P  P PA    +  +      P P G      P GP G DG  G  G + P
Sbjct: 1109 RGFPGNPGAPGSPGPAGQQGAIGS------PGPAGPRGPVGPSGPPGKDGTSGHPGPIGP 1162

Query: 309  HHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGG 349
                G+ G    +G P +      G   PPG P   G   G
Sbjct: 1163 PGPRGNRGERGSEGSPGH-----PGQPGPPGPPGAPGPCCG 1198



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 71/274 (25%), Positives = 100/274 (36%), Gaps = 44/274 (16%)

Query: 94   AAAAPSPVLGNIPPNDGMPGGPIPPG-----FFQGPPGSQPSP-HAQPP-PHNPSSMMGP 146
            A  A  P     P +DG+PG    PG        G PG+  +P H  PP P  P+   G 
Sbjct: 1004 AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGD 1063

Query: 147  HSQP----PGGVPGTQPL--LPNSMDPTRQQGHPNMGGSM----QRMNPPRGMGPMGPGP 196
              +     P G PG       P    P   +G     G+      R  P     P  PGP
Sbjct: 1064 RGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGP 1123

Query: 197  QNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPP 256
                +G +    S GPA P   +GP +G P  +  S +  P     P    G  G  G P
Sbjct: 1124 ----AGQQGAIGSPGPAGPRGPVGP-SGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSP 1178

Query: 257  GTPIMPSPADSTNSSDNIYTMINPVPPGG-SRSNFPMGPGSDGPMGG--MGGMEPHH--- 310
            G P  P P               P PPG        +G  +   +GG   GG  P++   
Sbjct: 1179 GHPGQPGP---------------PGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDE 1223

Query: 311  -MNGSLGSGDIDGLPKNSPNNISGISNPPGTPRD 343
             M+  + + +I    K+    I  + +P G+ ++
Sbjct: 1224 PMDFKINTDEIMTSLKSVNGQIESLISPDGSRKN 1257


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 67/200 (33%), Positives = 77/200 (38%), Gaps = 25/200 (12%)

Query: 106 PPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQP--PGGVP---GTQ 158
           PP  G P GP P G    QGPP     P   PPP   +   GP  +P  P G P   G Q
Sbjct: 114 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEG-PPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 172

Query: 159 PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGIN 218
              P    P + +G P  GG+  +  PPR   P GP PQ       PPP    P  P   
Sbjct: 173 SQGPPP-HPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQ 231

Query: 219 MG-------PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSS 271
            G       P  G+P   P    + P     PG   GPP  GG P  P +P PA      
Sbjct: 232 GGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQP-LPPPAGKPQGP 290

Query: 272 DNIYTMINPVPPGGSRSNFP 291
                   P PP G R + P
Sbjct: 291 --------PPPPQGGRPHRP 302



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 87/289 (30%), Positives = 103/289 (35%), Gaps = 48/289 (16%)

Query: 83  SSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGG-------PIPPGFFQGPPGSQPSPHAQP 135
           SS      D S   +PS + G   P    P G       P PPG  +G P  Q    +Q 
Sbjct: 14  SSAQSLNEDVSQEESPSVISGK--PEGRRPQGGNQPQRTPPPPGKPEGRP-PQGGNQSQG 70

Query: 136 PPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPG 195
           PP  P    GP   PP G   +Q   P    P + +G P  GG+  +  PPR   P GP 
Sbjct: 71  PPPRPGKPEGP---PPQGGNQSQGPPPR---PGKPEGQPPQGGNQSQGPPPRPGKPEGPP 124

Query: 196 PQNYGSGMRPPP---NSLGPAMPGINMG----PGAGRP-WPNPNSANSIPYSSSSPGTYV 247
           PQ       PPP      GP   G N      P  G+P  P P   N        PG   
Sbjct: 125 PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPE 184

Query: 248 GPP--GGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNF-PMGPGSDGPMGGMG 304
           GPP  GG    G P  P   +             P P GG++S   P  PG        G
Sbjct: 185 GPPPQGGNQSQGPPPRPGKPE------------GPPPQGGNQSQGPPPRPGKPEGPPSQG 232

Query: 305 GMEPHHMNGSLGSGDIDGLPKNSP---NNISGISNPPGTPRDDGELGGN 350
           G +P       G     G P+  P    N      PPG P+     GGN
Sbjct: 233 GNKPQ------GPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGN 275



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 59/177 (33%), Positives = 67/177 (37%), Gaps = 32/177 (18%)

Query: 98  PSPVLGNI----PPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPP---------PHNPSS 142
           P P  GN     PP  G P GP P G    QGPP     P   PP         P  P  
Sbjct: 144 PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGK 203

Query: 143 MMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSG 202
             GP   PP G   +Q   P    P + +G P+ GG+  +  PP    P GP PQ     
Sbjct: 204 PEGP---PPQGGNQSQGPPPR---PGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKP 257

Query: 203 MRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTP 259
            RPPP       PG   GP    P P  N    +P  +  P     PP GG P   P
Sbjct: 258 QRPPP-------PGRPQGP----PPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPP 303



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 46/126 (36%), Positives = 50/126 (39%), Gaps = 14/126 (11%)

Query: 98  PSPVLGNI----PPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQP- 150
           P P  GN     PP  G P GP P G    QGPP     P   PP    +   GP   P 
Sbjct: 186 PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEG-PPSQGGNKPQGPPPHPG 244

Query: 151 -PGGVP---GTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPP 206
            P G P   G +P  P    P R QG P  GG+ Q+  PP    P GP P   G     P
Sbjct: 245 KPQGPPPQEGNKPQRPPP--PGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRP 302

Query: 207 PNSLGP 212
           P    P
Sbjct: 303 PQGQPP 308


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 88/256 (34%), Positives = 104/256 (40%), Gaps = 38/256 (14%)

Query: 106 PPNDGMPGGPIPPGFFQGPPG-SQPSPHAQPPPHNPS--SMMGPHSQPPGGVPGTQPLLP 162
           PP    P GP  P  F G PG  +P  H QP P  P   S MG  + PPG        LP
Sbjct: 81  PPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMG-KAGPPG--------LP 131

Query: 163 NSMDPTRQ---QGHPNMGGSMQRMNPPRGMGPMG-PGPQNYGSGMRPP--PNSLG-PAMP 215
             + P  Q   +G P + G      PP   GP G PGP    SG+  P  P + G P  P
Sbjct: 132 GKVGPPGQPGLRGEPGIRGDQGLRGPP---GPPGLPGP----SGITIPGKPGAQGVPGPP 184

Query: 216 GINMGPG-AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPAD-STNSSDN 273
           G    PG  G P P  +           PG   G PG GG PG P +P PA       D 
Sbjct: 185 GFQGEPGPQGEPGPPGDRGLKGDNGVGQPG-LPGAPGQGGAPGPPGLPGPAGLGKPGLDG 243

Query: 274 IYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNIS 332
           +     P  PG    + P G PG  G  G +G   P  ++G +G     GLP   P   S
Sbjct: 244 L-----PGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG-VGVPGAAGLP--GPQGPS 295

Query: 333 GISNPPGTPRDDGELG 348
           G    PGT    G +G
Sbjct: 296 GAKGEPGTRGPPGLIG 311



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 83/264 (31%), Positives = 98/264 (37%), Gaps = 43/264 (16%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMG---------PHS 148
           P P    IP   G  G P PPG FQG PG    P  +P P     + G         P +
Sbjct: 164 PGPSGITIPGKPGAQGVPGPPG-FQGEPG----PQGEPGPPGDRGLKGDNGVGQPGLPGA 218

Query: 149 QPPGGVPGTQPLL-PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNYGSGMRPP 206
              GG PG   L  P  +      G P   G      PP   GP G PG      G + P
Sbjct: 219 PGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPG----AVGPKGP 274

Query: 207 PNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPP--GTPIMPSP 264
           P   G  +PG      AG P P   S      +   PGT  GPPG  GP   G P +P P
Sbjct: 275 PGVDGVGVPG-----AAGLPGPQGPSG-----AKGEPGTR-GPPGLIGPTGYGMPGLPGP 323

Query: 265 ADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP 324
                 +     + +   PG         PG  GP  G+GG  P  + GS G     G P
Sbjct: 324 KGDRGPAGVPGLLGDRGEPGEDGE-----PGEQGPQ-GLGG--PPGLPGSAGLPGRRGPP 375

Query: 325 KNSPNNISGISNPPGTPRDDGELG 348
              P   +G   PPG P   G+ G
Sbjct: 376 --GPKGEAGPGGPPGVPGIRGDQG 397



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 86/307 (28%), Positives = 106/307 (34%), Gaps = 74/307 (24%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGT 157
           P P     P  DG+PG P   G   GPPG  P P  +P    P    GP      GVPG 
Sbjct: 231 PGPAGLGKPGLDGLPGAPGDKGE-SGPPGV-PGPRGEPGAVGPK---GPPGVDGVGVPGA 285

Query: 158 QPLLPNSMDPTRQQGHPNMGGSMQRMNP----------PRG-MGPMG------------- 193
             L P    P+  +G P   G    + P          P+G  GP G             
Sbjct: 286 AGL-PGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGE 344

Query: 194 ------PGPQNYGS-----------GMRPPPNSLG-------PAMPGI--NMGPG--AGR 225
                  GPQ  G            G R PP   G       P +PGI  + GP   AG+
Sbjct: 345 DGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGK 404

Query: 226 PWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGG 285
           P         +P     PG + GPPG  GP G P           +  +    +   PG 
Sbjct: 405 P--------GVPGERGLPGAH-GPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ 455

Query: 286 SRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP---KNSPNNISGISNPPGTP 341
                P G PG  GP G +G   P  + G  G   + G P   +      +G + PPG P
Sbjct: 456 PGLRGPSGIPGLQGPAGPIG---PQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVP 512

Query: 342 RDDGELG 348
              G  G
Sbjct: 513 GSPGITG 519



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 68/219 (31%), Positives = 78/219 (35%), Gaps = 38/219 (17%)

Query: 106 PPNDGMPGGP--IP-------PGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-----P 151
           P  +  PGGP  +P       P    G PG  P     P  H P    GP  +P     P
Sbjct: 377 PKGEAGPGGPPGVPGIRGDQGPSGLAGKPGV-PGERGLPGAHGPPGPTGPKGEPGFTGRP 435

Query: 152 GGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYGSGMRPPPNSL 210
           GG PG    L    D     G P   G       P   GP GP GPQ    G++  P   
Sbjct: 436 GG-PGVAGALGQKGD----LGLPGQPGLRGPSGIPGLQGPAGPIGPQGL-PGLKGEPGLP 489

Query: 211 GPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNS 270
           GP   G    PG   P   P     +P    SPG   GPPG  GPPG P  P   D T  
Sbjct: 490 GPPGEGRAGEPGTAGPTGPPG----VP---GSPGI-TGPPGPPGPPGPPGAPGAFDETG- 540

Query: 271 SDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPH 309
                 +     P G      +G G   P  G+G +  H
Sbjct: 541 ------IAGLHLPNGGVEGAVLGKGGK-PQFGLGELSAH 572



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 73/266 (27%), Positives = 88/266 (33%), Gaps = 54/266 (20%)

Query: 110 GMPGGPIPPGFFQGPPGSQPSPHAQPPP-------HNPSSMMGPHS-QPPGGVPGT---- 157
           G+PG    PG  QGP G++  P  + PP       +    + GP   + P GVPG     
Sbjct: 281 GVPGAAGLPGP-QGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDR 339

Query: 158 ----QPLLPNSMDPTRQQGHPNMGGSMQ---RMNPPRGMGPMGPGPQNYGSGMRPPPNSL 210
               +   P    P    G P + GS     R  PP   G  GPG      G+R      
Sbjct: 340 GEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPS 399

Query: 211 G----PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT--------------YVGPPGG 252
           G    P +PG    PGA  P P P      P  +  PG                 G PG 
Sbjct: 400 GLAGKPGVPGERGLPGAHGP-PGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGL 458

Query: 253 GGPPGTPIMPSPADSTNSSDNIYTMINPV---PPGGSRSN------------FPMGPGSD 297
            GP G P +  PA              P    PPG  R+              P  PG  
Sbjct: 459 RGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGIT 518

Query: 298 GPMGGMGGMEPHHMNGSLGSGDIDGL 323
           GP G  G   P    G+     I GL
Sbjct: 519 GPPGPPGPPGPPGAPGAFDETGIAGL 544



 Score = 35.4 bits (80), Expect = 0.082
 Identities = 31/102 (30%), Positives = 34/102 (33%), Gaps = 6/102 (5%)

Query: 247 VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGM 306
           VGPP   G      MP P    +          P PPG      P GP       GMG  
Sbjct: 52  VGPPFREGKGQYLEMPLPLLPMDLKGE------PGPPGKPGPRGPPGPPGFPGKPGMGKP 105

Query: 307 EPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
             H   G  G      + K  P  + G   PPG P   GE G
Sbjct: 106 GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPG 147



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 28/78 (35%), Positives = 33/78 (42%), Gaps = 10/78 (12%)

Query: 105 IPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSS--MMGPHSQP-PGGVPGTQPLL 161
           +P   G PG P PPG  +G  G   +     PP  P S  + GP   P P G PG     
Sbjct: 479 LPGLKGEPGLPGPPG--EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGA---- 532

Query: 162 PNSMDPTRQQG-HPNMGG 178
           P + D T   G H   GG
Sbjct: 533 PGAFDETGIAGLHLPNGG 550


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 83/268 (30%), Positives = 99/268 (36%), Gaps = 50/268 (18%)

Query: 110 GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGT--------QPLL 161
           G PG P P GF QGPPG    P A  P       MGP   P  G PG         +P  
Sbjct: 191 GPPGAPGPQGF-QGPPGEPGEPGASGP-------MGPRGPP--GPPGKNGDDGEAGKPGR 240

Query: 162 PNSMDPTRQQGHPNMGGS--MQRMNPPRGM----------GPMGPGPQNYGSGMRPPPNS 209
           P    P   QG   + G+  +  M   RG           GP GP  +    G    P  
Sbjct: 241 PGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQ 300

Query: 210 LGP-AMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIM------P 262
           +GP  +PG    PGA    P P  A     ++ + G   GP G  GPPG P         
Sbjct: 301 MGPRGLPGERGRPGA----PGPAGARGNDGATGAAGP-PGPTGPAGPPGFPGAVGAKGEA 355

Query: 263 SPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDID 321
            P     S         P PPG + +  P G PG+DG  G  G       NG+ G     
Sbjct: 356 GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGA------NGAPGIAGAP 409

Query: 322 GLP-KNSPNNISGISNPPGTPRDDGELG 348
           G P    P+   G   PPG   + GE G
Sbjct: 410 GFPGARGPSGPQGPGGPPGPKGNSGEPG 437



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 80/263 (30%), Positives = 97/263 (36%), Gaps = 38/263 (14%)

Query: 108  NDGMPGGPIPPGFFQGP-------PGSQPSPHAQPPPHNPSSMMG-PHSQPPGGVPGTQP 159
            N G PG P P G   G        P  +P     P P  P+   G P +  P G PGT  
Sbjct: 891  NAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGT-- 948

Query: 160  LLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQ--NYGSGMRPPPNSLGPAMPG 216
              P       Q+G   + G       P   GP G PG Q  +  SG R PP  +GP  PG
Sbjct: 949  --PGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGP--PG 1004

Query: 217  INMGPGAGRPWPNPNSANSIPYSSSSPGTY--------VGPPGGGGPPGTPIMPSPADST 268
            +   PG       P +  S P    SPG           GPPG  G PG P    PA  +
Sbjct: 1005 LAGPPGESGREGAPGAEGS-PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKS 1063

Query: 269  NSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNS 327
                       P  P G     P+GP G+ GP G  G        G  G   I G     
Sbjct: 1064 GDRGET----GPAGPAG-----PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKG--HRG 1112

Query: 328  PNNISGISNPPGTPRDDGELGGN 350
             + + G   PPG+P + G  G +
Sbjct: 1113 FSGLQGPPGPPGSPGEQGPSGAS 1135



 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 88/286 (30%), Positives = 103/286 (36%), Gaps = 47/286 (16%)

Query: 93   SAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHN--------PSSMM 144
            S  A P+   G  P + G PG P P GF  GPPG+   P A+  P +        P    
Sbjct: 787  SGPAGPTGARG-APGDRGEPGPPGPAGF-AGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844

Query: 145  GPHSQPPG-----GVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQN 198
            GP + PPG     G PG +     S  P    G P   G +    P    GP G PGP  
Sbjct: 845  GP-AGPPGPIGNVGAPGAKG-ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAG 902

Query: 199  YGSGMRP--------------PPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPG 244
               G  P              PP   GPA  G    PGA  P   P +    P   +   
Sbjct: 903  KEGGKGPRGETGPAGRPGEVGPPGPPGPA--GEKGSPGADGPAGAPGTPG--PQGIAGQR 958

Query: 245  TYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGM 303
              VG PG  G  G P +P P+                PPG      PMG PG  GP G  
Sbjct: 959  GVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG------PMGPPGLAGPPGES 1012

Query: 304  GGMEPHHMNGSLGSGDIDGLP-KNSPNNISGISNPPGTPRDDGELG 348
            G        G+ GS   DG P        +G + PPG P   G  G
Sbjct: 1013 G---REGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPG 1055



 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 87/289 (30%), Positives = 102/289 (35%), Gaps = 56/289 (19%)

Query: 97  APSPVLGNIPPNDGMPGGPIPPGFFQGPPG---------------------SQPSPHAQP 135
           A  P    IP   G+PG P PPG   GPPG                     S P P    
Sbjct: 126 AGPPGRDGIPGQPGLPGPPGPPG-PPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMG-- 182

Query: 136 PPHNPSSMMGPHSQP-------PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRG 188
            P  P  + GP   P       P G PG +P     M P    G P   G       P  
Sbjct: 183 -PSGPRGLPGPPGAPGPQGFQGPPGEPG-EPGASGPMGPRGPPGPPGKNGDDGEAGKPGR 240

Query: 189 MGPMG-PGPQNYGSGMRPPPNSLG-PAM------PGINMGPGAGRPWPNPNSANSIPYSS 240
            G  G PGPQ    G R  P + G P M       G++   G   P   P      P  +
Sbjct: 241 PGERGPPGPQ----GARGLPGTAGLPGMKGHRGFSGLDGAKGDAGP-AGPKGEPGSPGEN 295

Query: 241 SSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGP 299
            +PG  +GP G  G  G P  P PA     +D       P  P G     P G PG  G 
Sbjct: 296 GAPG-QMGPRGLPGERGRPGAPGPA-GARGNDGATGAAGPPGPTG-----PAGPPGFPGA 348

Query: 300 MGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
           +G  G   P    GS G   + G P   P   +G + P G P  DG+ G
Sbjct: 349 VGAKGEAGPQGPRGSEGPQGVRGEP--GPPGPAGAAGPAGNPGADGQPG 395



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 78/260 (30%), Positives = 97/260 (37%), Gaps = 47/260 (18%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPG--GVP 155
           P P        +  P GP  P   +G PG +     +P P  P+   G    PPG  G P
Sbjct: 772 PGPAGAPGDKGESGPSGPAGPTGARGAPGDR----GEPGPPGPAGFAG----PPGADGQP 823

Query: 156 GTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGP-QNYGS-GMRPPPNSLGP 212
           G              +G P   G+     PP   GP G PGP  N G+ G +    S GP
Sbjct: 824 GA-------------KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP 870

Query: 213 AMPGINMGPG-AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSS 271
             PG    PG AGR  P   S N+            GPPG  GP G      P   T  +
Sbjct: 871 --PGATGFPGAAGRVGPPGPSGNA------------GPPGPPGPAGKEGGKGPRGETGPA 916

Query: 272 DNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNN 330
                +  P PPG +       PG+DGP G  G   P  + G  G   + GLP +     
Sbjct: 917 GRPGEVGPPGPPGPAGEK--GSPGADGPAGAPGTPGPQGIAGQRG---VVGLPGQRGERG 971

Query: 331 ISGISNPPGTPRDDGELGGN 350
             G+  P G P   G  G +
Sbjct: 972 FPGLPGPSGEPGKQGPSGAS 991



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 84/285 (29%), Positives = 95/285 (33%), Gaps = 59/285 (20%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHS--------QPPG----- 152
           P   G+PG   PPG   G PG Q  P     P  PS   G            PPG     
Sbjct: 640 PGFQGLPGPAGPPGE-AGKPGEQGVPGDLGAP-GPSGARGERGFPGERGVQGPPGPAGPR 697

Query: 153 ---GVPGTQ--------PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-----GP 196
              G PG          P  P S      QG P   G+     P    G  GP      P
Sbjct: 698 GANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSP 757

Query: 197 QNYG-SGMRPPPNSLGPA-MPGINMGPGAGRPWPNPNSANSIPYSSSSPGT-----YVGP 249
              G  G+  P    GPA  PG     G   P   P  A   P     PG      + GP
Sbjct: 758 GKDGVRGLTGPIGPPGPAGAPGDKGESGPSGP-AGPTGARGAPGDRGEPGPPGPAGFAGP 816

Query: 250 PGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEP 308
           PG  G PG    P  A +   +          PPG      P GP G  GP+G +G    
Sbjct: 817 PGADGQPGAKGEPGDAGAKGDAG---------PPG------PAGPAGPPGPIGNVGAPGA 861

Query: 309 HHMNGSLGSGDIDGLP----KNSPNNISGISNPPGTPRDDGELGG 349
               GS G     G P    +  P   SG + PPG P   G+ GG
Sbjct: 862 KGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGG 906



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 85/276 (30%), Positives = 98/276 (35%), Gaps = 42/276 (15%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-P 151
           + AA P+   GN P  DG PG         G PG   +P   P    PS   GP   P P
Sbjct: 379 AGAAGPA---GN-PGADGQPGAKGA----NGAPGIAGAP-GFPGARGPSGPQGPGGPPGP 429

Query: 152 GGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNP-----PRGM----GPMG-PGP--QNY 199
            G  G +P  P S   T  +G P   G      P      RG     GP G PGP  +  
Sbjct: 430 KGNSG-EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG 488

Query: 200 GSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTP 259
           G G R  P + G A P    GP   R  P P      P  +  PG   G PG  G  G+P
Sbjct: 489 GPGSRGFPGADGVAGP---KGPAGERGSPGPAGPKGSPGEAGRPGE-AGLPGAKGLTGSP 544

Query: 260 IMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGD 319
             P P   T           P PPG         PG+ G  G MG   P    G  G   
Sbjct: 545 GSPGPDGKTGPPGPAGQDGRPGPPG--------PPGARGQAGVMGFPGPKGAAGEPGKAG 596

Query: 320 IDGLP-------KNSPNNISGISNPPGTPRDDGELG 348
             G+P           +  +G   PPG     GE G
Sbjct: 597 ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG 632



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 72/250 (28%), Positives = 91/250 (36%), Gaps = 23/250 (9%)

Query: 106 PPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGT--QPLL 161
           P   G PG    PG     G PGS P P  +  P  P+   G    P  G PG   Q  +
Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGS-PGPDGKTGPPGPAGQDGRPGPP--GPPGARGQAGV 579

Query: 162 PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGP 221
                P    G P   G      PP  +GP G   +   +G + PP   GPA      GP
Sbjct: 580 MGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGE---AGAQGPPGPAGPAGERGEQGP 636

Query: 222 GAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPV 281
            AG P         +P  +  PG   G PG  G PG    P P+ +              
Sbjct: 637 -AGSP-----GFQGLPGPAGPPGE-AGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQG 689

Query: 282 PPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 340
           PPG +      G PG+DG  G  G        GS G+  + G+P       +G+  P G 
Sbjct: 690 PPGPAGPRGANGAPGNDGAKGDAGA---PGAPGSQGAPGLQGMP--GERGAAGLPGPKGD 744

Query: 341 PRDDGELGGN 350
             D G  G +
Sbjct: 745 RGDAGPKGAD 754



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 81/278 (29%), Positives = 96/278 (34%), Gaps = 56/278 (20%)

Query: 112 PGGPIPPGFFQG--PPGSQ-PSPHAQPPPHNPSSMMGPHSQ-----PPG--GVPGTQPLL 161
           PG  +P G      P GS+ P+         P    GP        PPG  G+PG QP L
Sbjct: 82  PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPG-QPGL 140

Query: 162 PNSMDPTRQQGHPNMGG-------------SMQRMNPPRGMGPMGPGPQNYGSGMRPPPN 208
           P    P    G P +GG             S   ++ P  MGP GP       G+  PP 
Sbjct: 141 PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGP------RGLPGPPG 194

Query: 209 SLGP----AMPGINMGPGAGRPW-----PNPNSANSIPYSSSSPGT-----YVGPPGGGG 254
           + GP      PG    PGA  P      P P   N     +  PG        GP G  G
Sbjct: 195 APGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARG 254

Query: 255 PPGTPIMPSPADSTNSS--DNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMN 312
            PGT  +P        S  D       P  P G        PGS G  G  G M P  + 
Sbjct: 255 LPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGE-------PGSPGENGAPGQMGPRGLP 307

Query: 313 GSLGSGDIDGLPKNSPNN--ISGISNPPGTPRDDGELG 348
           G  G     G P  +  N   +G + PPG     G  G
Sbjct: 308 GERGRPGAPG-PAGARGNDGATGAAGPPGPTGPAGPPG 344



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 52/167 (31%), Positives = 66/167 (39%), Gaps = 27/167 (16%)

Query: 106  PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGP-HSQPPGGVPGTQPLLPNS 164
            P   G PG P P G     P  +     +  P  P+  +GP  ++ P G  G +      
Sbjct: 1045 PGAPGAPGAPGPVG-----PAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPR----GD 1095

Query: 165  MDPTRQQG------HPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLG-PAMPGI 217
               T +QG      H    G      PP   G  GP   +  +G R PP S G P   G+
Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGL 1155

Query: 218  NMGPG-AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPS 263
            N  PG  G P P   + ++ P         VGPPG  GPPG P  PS
Sbjct: 1156 NGLPGPIGPPGPRGRTGDAGP---------VGPPGPPGPPGPPGPPS 1193



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 58/230 (25%), Positives = 71/230 (30%), Gaps = 49/230 (21%)

Query: 110  GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPG-GVPGTQ--PLLPNSMD 166
            G+PG    PG  QGP G+       P P  P  + GP  +    G PG +  P    S  
Sbjct: 974  GLPGPSGEPGK-QGPSGAS-GERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPG 1031

Query: 167  PTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGA--- 223
                +G     G       P   GP+GP  ++   G   P    GP  P    GP     
Sbjct: 1032 AKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG 1091

Query: 224  --------------------------GRPWPNPNSANSIPYSSSSPGTYVGPPGGG---- 253
                                      G P P  +     P  +S P    GPPG      
Sbjct: 1092 PRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPG 1151

Query: 254  -----GPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDG 298
                 G PG    P P   T  +  +     P PPG      P GP S G
Sbjct: 1152 KDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPG------PPGPPSAG 1195



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 32/90 (35%), Positives = 36/90 (40%), Gaps = 6/90 (6%)

Query: 122  QGPPGSQPSPHAQPPPHNPSSMMGPHSQPPG--GVPGTQPL--LPNSMDPTRQQGHPNMG 177
            QGPPG   SP  Q P    S   GP   PPG  G PG   L  LP  + P   +G     
Sbjct: 1117 QGPPGPPGSPGEQGPS-GASGPAGPRG-PPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDA 1174

Query: 178  GSMQRMNPPRGMGPMGPGPQNYGSGMRPPP 207
            G +    PP   GP GP    +     P P
Sbjct: 1175 GPVGPPGPPGPPGPPGPPSAGFDFSFLPQP 1204


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 84/304 (27%), Positives = 103/304 (33%), Gaps = 56/304 (18%)

Query: 98   PSPVLGNI-PPND-GMPGGPIPPGFFQGPPG--------------SQPSPHAQPPPHNPS 141
            P   +GN+ PP + G PG    PG  QG PG               QP     P P  P+
Sbjct: 1113 PPGGVGNLGPPGEKGEPGESGSPGI-QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1171

Query: 142  SMMGPHSQP-PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGP 196
               GP   P P G PG  P  P    P  Q G     G       P   GP G    PGP
Sbjct: 1172 GDDGPKGNPGPVGFPG-DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP 1230

Query: 197  --------------QNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSS 242
                          +  G G +  P ++G       +GP      P P+    +P S   
Sbjct: 1231 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1290

Query: 243  PGT-----YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGS 296
             G        GPPG  GPPG P +   A +     +   +    PPG        G PG 
Sbjct: 1291 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1350

Query: 297  DGPMGGMGGMEPHHMNGSLGSGDIDGLP-------------KNSPNNISGISNPPGTPRD 343
             G  G  G M     +G +G G   GLP                P    G+  PPG P  
Sbjct: 1351 QGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1410

Query: 344  DGEL 347
             GE+
Sbjct: 1411 PGEV 1414



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 80/256 (31%), Positives = 93/256 (36%), Gaps = 43/256 (16%)

Query: 98   PSPV-LGNIPPNDGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGV 154
            P P+ L  +P   G  G  G + P    GPPG  P P     P  P+   GP   PPGGV
Sbjct: 1066 PGPIGLQGLPGPSGEKGETGDVGP---MGPPGP-PGPRG---PAGPNGADGPQG-PPGGV 1117

Query: 155  PGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAM 214
                     ++ P  ++G P   GS      P   GP G   +   SG    P   GP  
Sbjct: 1118 --------GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1169

Query: 215  PGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNI 274
            P  + GP  G P P              PG   GPPG GGP G       A      D  
Sbjct: 1170 PTGDDGP-KGNPGP-----------VGFPGD-PGPPGEGGPRG----QDGAKGDRGEDG- 1211

Query: 275  YTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNIS 332
                 P  PG +  N P GP G  GP G  G        G+ G     G P K  P    
Sbjct: 1212 -EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGP---V 1267

Query: 333  GISNPPGTPRDDGELG 348
            G + P G P  DG  G
Sbjct: 1268 GPAGPAGKPGPDGLRG 1283



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 69/243 (28%), Positives = 89/243 (36%), Gaps = 22/243 (9%)

Query: 112  PGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPL--LPNSMDPTR 169
            P GPI P    G  G+   P A+ P  +  +     ++   G PG   L  LP    P+ 
Sbjct: 1023 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPG---PSG 1079

Query: 170  QQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPN 229
            ++G     G +  M PP   GP GP   N   G + PP  +G      N+GP   +  P 
Sbjct: 1080 EKGET---GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG------NLGPPGEKGEPG 1130

Query: 230  PNSANSIPYSSS--SPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSR 287
             + +  I        P    G  G  G PG P  P P   T          NP P G   
Sbjct: 1131 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG---PKGNPGPVGFPG 1187

Query: 288  SNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDG-LPKNSPNNISGISNPPGTPRDDGE 346
               P  PG  GP G  G       +G  G     G   +N P    G   P G+P  +G 
Sbjct: 1188 DPGP--PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGR 1245

Query: 347  LGG 349
             GG
Sbjct: 1246 QGG 1248



 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 83/293 (28%), Positives = 103/293 (35%), Gaps = 65/293 (22%)

Query: 109 DGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP--PG--------GVPG 156
           DG PG  G I     +G  G  P    +  P  P    GP   P  PG        GVPG
Sbjct: 655 DGFPGFKGDIGVKGDRGEVGV-PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 713

Query: 157 TQPLLPNSMDPTRQQGHPNMGGS--------MQRMNPPRG-MGPMGP----GPQ------ 197
             P  P    P    G P   G+        +   + PRG  GP GP    GP+      
Sbjct: 714 L-PGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 772

Query: 198 -----NYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPG 251
                + G G   PP   G P   G N  PG   P P P   + +P      G  VG  G
Sbjct: 773 GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP-PGPPGKDGLPGHPGQRGE-VGFQG 830

Query: 252 GGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--------------GSRSN--FPMGPG 295
             GPPG P +  P  +   +  +    +P PPG              G++ +   P  PG
Sbjct: 831 KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 890

Query: 296 SDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            DGP G  G      + G+ G   + G          G S PPG     GE G
Sbjct: 891 KDGPAGLRGFPGERGLPGTAGGPGLKG--------NEGPSGPPGPAGSPGERG 935



 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 80/270 (29%), Positives = 98/270 (36%), Gaps = 38/270 (14%)

Query: 102  LGNIPPNDGMPGGPIPPGFF-----QGPPGSQPSPHAQPP-----PHNPSSMMGPHSQPP 151
            L   P   G+PG    PG        GPPG   SP  +       P  P    GP   PP
Sbjct: 897  LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG-PP 955

Query: 152  G-----GVPGTQ-PLLPNSMDPTR-QQGHPNMGGSMQRMNPPRGMGPMG-PGPQNY--GS 201
            G     GVPG + P+ P   D  +   G P   G           G +G PG +      
Sbjct: 956  GAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNK 1015

Query: 202  GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT--YVGPPGGGGPPGTP 259
            G   PP   GP  P    G       P          +    GT  + GPP   GP G  
Sbjct: 1016 GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP---GPIGLQ 1072

Query: 260  IMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSG 318
             +P P+     + ++  M  P PPG      P GP G+DGP G  GG+      G+LG  
Sbjct: 1073 GLPGPSGEKGETGDVGPMGPPGPPG---PRGPAGPNGADGPQGPPGGV------GNLGPP 1123

Query: 319  DIDGLPKNSPNNISGISNPPGTPRDDGELG 348
               G P  S +   GI   PG     GE G
Sbjct: 1124 GEKGEPGESGS--PGIQGEPGVKGPRGERG 1151



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 70/250 (28%), Positives = 89/250 (35%), Gaps = 41/250 (16%)

Query: 106  PPND-GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPS-----SMMGPHSQP-PGGVPGTQ 158
            PP + G+PG P  P  F GP G    P     P +P         G    P P GV G Q
Sbjct: 786  PPGERGLPG-PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 844

Query: 159  PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGIN 218
                    P  ++GHP   G      PP   G  G   +    G   PP + G       
Sbjct: 845  G-AAGETGPMGERGHPGPPG------PPGEQGLPGTAGKEGTKGDPGPPGAPG------K 891

Query: 219  MGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMI 278
             GP   R +P       +P ++  PG   G  G  GPPG    P    +  S        
Sbjct: 892  DGPAGLRGFP---GERGLPGTAGGPG-LKGNEGPSGPPGPAGSPGERGAAGSG------- 940

Query: 279  NPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPP 338
             P+ P G        PG  GP G  G        G +G    DG+    P  + G + PP
Sbjct: 941  GPIGPPGR-------PGPQGPPGAAGEKGVPGEKGPIGPTGRDGV--QGPVGLPGPAGPP 991

Query: 339  GTPRDDGELG 348
            G   +DG+ G
Sbjct: 992  GVAGEDGDKG 1001



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 72/253 (28%), Positives = 87/253 (34%), Gaps = 27/253 (10%)

Query: 112 PGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMG-PHSQPPGGVPGTQPLLPNSMDPTRQ 170
           P GP  P    GPPG +     +        M G P  +   G  G  P LP       +
Sbjct: 432 PQGPRGPQGLTGPPG-KAGRRGRAGADGARGMPGDPGVKGDRGFDGL-PGLPG------E 483

Query: 171 QGHPNMGGSMQRMNPPRGMGPMGP----GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRP 226
           +GH    G+     PP   G  G     GP+    G   P   LGP  P    GP   R 
Sbjct: 484 KGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL-PGESGPRGLLGPKGPPGIPGPPGVRG 542

Query: 227 WPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGS 286
              P      P  S  P    GPPG  G PGT  +P P  +            P  PG  
Sbjct: 543 MDGPQG----PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 598

Query: 287 RSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 345
            S+ P G PG +GP G  G   P    G LG           P  + G+    G     G
Sbjct: 599 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG--------YPGPRGVKGVDGIRGLKGHKG 650

Query: 346 ELGGNFLHSFQND 358
           E G +    F+ D
Sbjct: 651 EKGEDGFPGFKGD 663



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 83/268 (30%), Positives = 96/268 (35%), Gaps = 40/268 (14%)

Query: 113  GGPI-PPGFF--QGPPGSQ-----PSPHAQPPPHNPSSMMGPHSQP----PGGVPGTQPL 160
            GGPI PPG    QGPPG+      P       P     + GP   P    P GV G    
Sbjct: 940  GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 999

Query: 161  LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGP----AMPG 216
                 DP    G     G+     PP   GP+GP  Q   +G    P + GP       G
Sbjct: 1000 KGEVGDP----GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1055

Query: 217  INMGPGAGRPWPNPNSANSIPYSSSSPGTY--VGPPGGGGPPGT--PIMPSPADSTNSSD 272
                 G   P P P     +P  S   G    VGP G  GPPG   P  P+ AD      
Sbjct: 1056 DEGTRGFNGP-PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1114

Query: 273  NIYTMINPV----PPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLG-------SGDI 320
                 + P      PG S S    G PG  GP G  G        G  G       +GD 
Sbjct: 1115 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD- 1173

Query: 321  DGLPKNSPNNISGISNPPGTPRDDGELG 348
            DG PK +P  + G    PG P + G  G
Sbjct: 1174 DG-PKGNPGPV-GFPGDPGPPGEGGPRG 1199



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 79/321 (24%), Positives = 96/321 (29%), Gaps = 89/321 (27%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLP--- 162
           PP    P G I P   QG PG    P  + PP        P S    G PGT  +LP   
Sbjct: 314 PPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL---PGSDGAPGPPGTSLMLPFRF 370

Query: 163 ---------------------------------------NSMDPTRQQGHPNMGGSMQRM 183
                                                      P  Q G P + G    +
Sbjct: 371 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 430

Query: 184 NPPRGMGPMG-PGPQNY--------GSGMRPPPNSLG----------PAMPGI--NMGPG 222
            P    GP G  GP             G R  P   G          P +PG   + G  
Sbjct: 431 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 490

Query: 223 AGRPWPNPNSAN------------SIPYSSSSPGTY--VGPPGGGGPPGTPIMPSPADST 268
             +  P P   +             +P  S   G     GPPG  GPPG   M  P    
Sbjct: 491 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 550

Query: 269 NSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNS 327
            S   +     P PPG   +     PG+ G  G  G + PH   G  G   + G+P  + 
Sbjct: 551 GS---LGPQGEPGPPGQQGT-----PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 602

Query: 328 PNNISGISNPPGTPRDDGELG 348
           P    G   PPGT  + G  G
Sbjct: 603 PPGHPGKEGPPGTKGNQGPSG 623



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 60/207 (28%), Positives = 72/207 (34%), Gaps = 30/207 (14%)

Query: 107  PNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMD 166
            P    P GP  P    GP G +  P +      P +        P G PG  P L     
Sbjct: 1261 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL-PGLRGDAG 1319

Query: 167  PTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGS--GMRPPPNSLGPAMPGINMG 220
               ++GHP + G +    PP   G  G    PGPQ      G    P + GP  PG   G
Sbjct: 1320 AKGEKGHPGLIGLI---GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPG---G 1373

Query: 221  PGAGRPWP-NPNSANSIPYSSSSPGT--YVGPPGGGGPPGTPIMPSPADSTNSS------ 271
            P  G P P  P  A          G     GPPG  GPPG  I P P      +      
Sbjct: 1374 P-PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDG 1432

Query: 272  DNIYTMINPVPPGGSRSNFPMGPGSDG 298
              +      +P GG+       PGS G
Sbjct: 1433 SRLMQEDEAIPTGGA-------PGSPG 1452



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 68/260 (26%), Positives = 88/260 (33%), Gaps = 55/260 (21%)

Query: 124 PPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSM--- 180
           P   QP    + P   PS +  P +Q            P S DPT  +    +  S+   
Sbjct: 236 PQNQQPHRAQRSPQQQPSRLHRPQNQE-----------PQSQDPTPGEEEEILESSLLPP 284

Query: 181 --QRMNPPRGM-GPMG-PGPQNYGSGMRPPPNSLGPA----MPGINMGPG-AGRPWP-NP 230
             +  + PRG+ G  G P     G  +  PP   GPA     PGI   PG  G P    P
Sbjct: 285 LEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP 344

Query: 231 NSANSIPYSSSSPGTYVGPPG-----------GGGPPGTPIMPSPADSTNSSDNIYTMIN 279
                +P S  +P    GPPG           GGG  G  +    A +          + 
Sbjct: 345 PGRAGLPGSDGAP----GPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALR 400

Query: 280 PVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPP 338
             PPG      PMG  G  GP+G  G       +G LG           P    G++ PP
Sbjct: 401 G-PPG------PMGYTGRPGPLGQPGSPGLKGESGDLG--------PQGPRGPQGLTGPP 445

Query: 339 GTPRDDGELGGNFLHSFQND 358
           G     G  G +       D
Sbjct: 446 GKAGRRGRAGADGARGMPGD 465


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 84/304 (27%), Positives = 103/304 (33%), Gaps = 56/304 (18%)

Query: 98   PSPVLGNI-PPND-GMPGGPIPPGFFQGPPG--------------SQPSPHAQPPPHNPS 141
            P   +GN+ PP + G PG    PG  QG PG               QP     P P  P+
Sbjct: 1092 PPGGVGNLGPPGEKGEPGESGSPGI-QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1150

Query: 142  SMMGPHSQP-PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGP 196
               GP   P P G PG  P  P    P  Q G     G       P   GP G    PGP
Sbjct: 1151 GDDGPKGNPGPVGFPG-DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP 1209

Query: 197  --------------QNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSS 242
                          +  G G +  P ++G       +GP      P P+    +P S   
Sbjct: 1210 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1269

Query: 243  PGT-----YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGS 296
             G        GPPG  GPPG P +   A +     +   +    PPG        G PG 
Sbjct: 1270 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1329

Query: 297  DGPMGGMGGMEPHHMNGSLGSGDIDGLP-------------KNSPNNISGISNPPGTPRD 343
             G  G  G M     +G +G G   GLP                P    G+  PPG P  
Sbjct: 1330 QGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1389

Query: 344  DGEL 347
             GE+
Sbjct: 1390 PGEV 1393



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 80/256 (31%), Positives = 93/256 (36%), Gaps = 43/256 (16%)

Query: 98   PSPV-LGNIPPNDGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGV 154
            P P+ L  +P   G  G  G + P    GPPG  P P     P  P+   GP   PPGGV
Sbjct: 1045 PGPIGLQGLPGPSGEKGETGDVGP---MGPPGP-PGPRG---PAGPNGADGPQG-PPGGV 1096

Query: 155  PGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAM 214
                     ++ P  ++G P   GS      P   GP G   +   SG    P   GP  
Sbjct: 1097 --------GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1148

Query: 215  PGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNI 274
            P  + GP  G P P              PG   GPPG GGP G       A      D  
Sbjct: 1149 PTGDDGP-KGNPGP-----------VGFPGD-PGPPGEGGPRG----QDGAKGDRGEDG- 1190

Query: 275  YTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNIS 332
                 P  PG +  N P GP G  GP G  G        G+ G     G P K  P    
Sbjct: 1191 -EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGP---V 1246

Query: 333  GISNPPGTPRDDGELG 348
            G + P G P  DG  G
Sbjct: 1247 GPAGPAGKPGPDGLRG 1262



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 69/243 (28%), Positives = 89/243 (36%), Gaps = 22/243 (9%)

Query: 112  PGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPL--LPNSMDPTR 169
            P GPI P    G  G+   P A+ P  +  +     ++   G PG   L  LP    P+ 
Sbjct: 1002 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPG---PSG 1058

Query: 170  QQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPN 229
            ++G     G +  M PP   GP GP   N   G + PP  +G      N+GP   +  P 
Sbjct: 1059 EKGET---GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG------NLGPPGEKGEPG 1109

Query: 230  PNSANSIPYSSS--SPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSR 287
             + +  I        P    G  G  G PG P  P P   T          NP P G   
Sbjct: 1110 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG---PKGNPGPVGFPG 1166

Query: 288  SNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDG-LPKNSPNNISGISNPPGTPRDDGE 346
               P  PG  GP G  G       +G  G     G   +N P    G   P G+P  +G 
Sbjct: 1167 DPGP--PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGR 1224

Query: 347  LGG 349
             GG
Sbjct: 1225 QGG 1227



 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 83/293 (28%), Positives = 103/293 (35%), Gaps = 65/293 (22%)

Query: 109 DGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP--PG--------GVPG 156
           DG PG  G I     +G  G  P    +  P  P    GP   P  PG        GVPG
Sbjct: 634 DGFPGFKGDIGVKGDRGEVGV-PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 692

Query: 157 TQPLLPNSMDPTRQQGHPNMGGS--------MQRMNPPRG-MGPMGP----GPQ------ 197
             P  P    P    G P   G+        +   + PRG  GP GP    GP+      
Sbjct: 693 L-PGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 751

Query: 198 -----NYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPG 251
                + G G   PP   G P   G N  PG   P P P   + +P      G  VG  G
Sbjct: 752 GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP-PGPPGKDGLPGHPGQRGE-VGFQG 809

Query: 252 GGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--------------GSRSN--FPMGPG 295
             GPPG P +  P  +   +  +    +P PPG              G++ +   P  PG
Sbjct: 810 KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 869

Query: 296 SDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            DGP G  G      + G+ G   + G          G S PPG     GE G
Sbjct: 870 KDGPAGLRGFPGERGLPGTAGGPGLKG--------NEGPSGPPGPAGSPGERG 914



 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 80/270 (29%), Positives = 98/270 (36%), Gaps = 38/270 (14%)

Query: 102  LGNIPPNDGMPGGPIPPGFF-----QGPPGSQPSPHAQPP-----PHNPSSMMGPHSQPP 151
            L   P   G+PG    PG        GPPG   SP  +       P  P    GP   PP
Sbjct: 876  LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG-PP 934

Query: 152  G-----GVPGTQ-PLLPNSMDPTR-QQGHPNMGGSMQRMNPPRGMGPMG-PGPQNY--GS 201
            G     GVPG + P+ P   D  +   G P   G           G +G PG +      
Sbjct: 935  GAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNK 994

Query: 202  GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT--YVGPPGGGGPPGTP 259
            G   PP   GP  P    G       P          +    GT  + GPP   GP G  
Sbjct: 995  GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP---GPIGLQ 1051

Query: 260  IMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSG 318
             +P P+     + ++  M  P PPG      P GP G+DGP G  GG+      G+LG  
Sbjct: 1052 GLPGPSGEKGETGDVGPMGPPGPPG---PRGPAGPNGADGPQGPPGGV------GNLGPP 1102

Query: 319  DIDGLPKNSPNNISGISNPPGTPRDDGELG 348
               G P  S +   GI   PG     GE G
Sbjct: 1103 GEKGEPGESGS--PGIQGEPGVKGPRGERG 1130



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 70/250 (28%), Positives = 89/250 (35%), Gaps = 41/250 (16%)

Query: 106 PPND-GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPS-----SMMGPHSQP-PGGVPGTQ 158
           PP + G+PG P  P  F GP G    P     P +P         G    P P GV G Q
Sbjct: 765 PPGERGLPG-PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 823

Query: 159 PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGIN 218
                   P  ++GHP   G      PP   G  G   +    G   PP + G       
Sbjct: 824 G-AAGETGPMGERGHPGPPG------PPGEQGLPGTAGKEGTKGDPGPPGAPG------K 870

Query: 219 MGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMI 278
            GP   R +P       +P ++  PG   G  G  GPPG    P    +  S        
Sbjct: 871 DGPAGLRGFP---GERGLPGTAGGPG-LKGNEGPSGPPGPAGSPGERGAAGSG------- 919

Query: 279 NPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPP 338
            P+ P G        PG  GP G  G        G +G    DG+    P  + G + PP
Sbjct: 920 GPIGPPGR-------PGPQGPPGAAGEKGVPGEKGPIGPTGRDGV--QGPVGLPGPAGPP 970

Query: 339 GTPRDDGELG 348
           G   +DG+ G
Sbjct: 971 GVAGEDGDKG 980



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 72/253 (28%), Positives = 87/253 (34%), Gaps = 27/253 (10%)

Query: 112 PGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMG-PHSQPPGGVPGTQPLLPNSMDPTRQ 170
           P GP  P    GPPG +     +        M G P  +   G  G  P LP       +
Sbjct: 411 PQGPRGPQGLTGPPG-KAGRRGRAGADGARGMPGDPGVKGDRGFDGL-PGLPG------E 462

Query: 171 QGHPNMGGSMQRMNPPRGMGPMGP----GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRP 226
           +GH    G+     PP   G  G     GP+    G   P   LGP  P    GP   R 
Sbjct: 463 KGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL-PGESGPRGLLGPKGPPGIPGPPGVRG 521

Query: 227 WPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGS 286
              P      P  S  P    GPPG  G PGT  +P P  +            P  PG  
Sbjct: 522 MDGPQG----PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 577

Query: 287 RSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 345
            S+ P G PG +GP G  G   P    G LG           P  + G+    G     G
Sbjct: 578 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG--------YPGPRGVKGVDGIRGLKGHKG 629

Query: 346 ELGGNFLHSFQND 358
           E G +    F+ D
Sbjct: 630 EKGEDGFPGFKGD 642



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 83/268 (30%), Positives = 96/268 (35%), Gaps = 40/268 (14%)

Query: 113  GGPI-PPGFF--QGPPGSQ-----PSPHAQPPPHNPSSMMGPHSQP----PGGVPGTQPL 160
            GGPI PPG    QGPPG+      P       P     + GP   P    P GV G    
Sbjct: 919  GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 978

Query: 161  LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGP----AMPG 216
                 DP    G     G+     PP   GP+GP  Q   +G    P + GP       G
Sbjct: 979  KGEVGDP----GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1034

Query: 217  INMGPGAGRPWPNPNSANSIPYSSSSPGTY--VGPPGGGGPPGT--PIMPSPADSTNSSD 272
                 G   P P P     +P  S   G    VGP G  GPPG   P  P+ AD      
Sbjct: 1035 DEGTRGFNGP-PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1093

Query: 273  NIYTMINPV----PPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLG-------SGDI 320
                 + P      PG S S    G PG  GP G  G        G  G       +GD 
Sbjct: 1094 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD- 1152

Query: 321  DGLPKNSPNNISGISNPPGTPRDDGELG 348
            DG PK +P  + G    PG P + G  G
Sbjct: 1153 DG-PKGNPGPV-GFPGDPGPPGEGGPRG 1178



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 79/321 (24%), Positives = 96/321 (29%), Gaps = 89/321 (27%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLP--- 162
           PP    P G I P   QG PG    P  + PP        P S    G PGT  +LP   
Sbjct: 293 PPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL---PGSDGAPGPPGTSLMLPFRF 349

Query: 163 ---------------------------------------NSMDPTRQQGHPNMGGSMQRM 183
                                                      P  Q G P + G    +
Sbjct: 350 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 409

Query: 184 NPPRGMGPMG-PGPQNY--------GSGMRPPPNSLG----------PAMPGI--NMGPG 222
            P    GP G  GP             G R  P   G          P +PG   + G  
Sbjct: 410 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 469

Query: 223 AGRPWPNPNSAN------------SIPYSSSSPGTY--VGPPGGGGPPGTPIMPSPADST 268
             +  P P   +             +P  S   G     GPPG  GPPG   M  P    
Sbjct: 470 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 529

Query: 269 NSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNS 327
            S   +     P PPG   +     PG+ G  G  G + PH   G  G   + G+P  + 
Sbjct: 530 GS---LGPQGEPGPPGQQGT-----PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581

Query: 328 PNNISGISNPPGTPRDDGELG 348
           P    G   PPGT  + G  G
Sbjct: 582 PPGHPGKEGPPGTKGNQGPSG 602



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 60/207 (28%), Positives = 72/207 (34%), Gaps = 30/207 (14%)

Query: 107  PNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMD 166
            P    P GP  P    GP G +  P +      P +        P G PG  P L     
Sbjct: 1240 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL-PGLRGDAG 1298

Query: 167  PTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGS--GMRPPPNSLGPAMPGINMG 220
               ++GHP + G +    PP   G  G    PGPQ      G    P + GP  PG   G
Sbjct: 1299 AKGEKGHPGLIGLI---GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPG---G 1352

Query: 221  PGAGRPWP-NPNSANSIPYSSSSPGT--YVGPPGGGGPPGTPIMPSPADSTNSS------ 271
            P  G P P  P  A          G     GPPG  GPPG  I P P      +      
Sbjct: 1353 P-PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDG 1411

Query: 272  DNIYTMINPVPPGGSRSNFPMGPGSDG 298
              +      +P GG+       PGS G
Sbjct: 1412 SRLMQEDEAIPTGGA-------PGSPG 1431



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 70/264 (26%), Positives = 88/264 (33%), Gaps = 53/264 (20%)

Query: 124 PPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPL-------LPNSMDP-TRQQGHPN 175
           P   QP    + P   PS +  P +Q P       P         P  ++P    +G P 
Sbjct: 236 PQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPG 295

Query: 176 MGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANS 235
             G    + PP   G   PGP     G R PP   G  +PG +  PG       P ++  
Sbjct: 296 PEGPAGLIGPPGIQG--NPGPVG-DPGERGPPGRAG--LPGSDGAPGP------PGTSLM 344

Query: 236 IPYSSSSPGTYVGP--------------------PGGGGPPGTPIMPSPADSTNSSDNIY 275
           +P+   S G   GP                     G  GP G    P P      S  + 
Sbjct: 345 LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP-GSPGLK 403

Query: 276 TMINPVPPGGSRSNFPMG----PGSDGPMGGMGGMEPHHMNGSLG-SGD--IDGLP---- 324
                + P G R   P G    PG  G  G  G      M G  G  GD   DGLP    
Sbjct: 404 GESGDLGPQGPRG--PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPG 461

Query: 325 KNSPNNISGISNPPGTPRDDGELG 348
           +      +G    PG P +DGE G
Sbjct: 462 EKGHRGDTGAQGLPGPPGEDGERG 485


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 84/304 (27%), Positives = 103/304 (33%), Gaps = 56/304 (18%)

Query: 98   PSPVLGNI-PPND-GMPGGPIPPGFFQGPPG--------------SQPSPHAQPPPHNPS 141
            P   +GN+ PP + G PG    PG  QG PG               QP     P P  P+
Sbjct: 1199 PPGGVGNLGPPGEKGEPGESGSPGI-QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1257

Query: 142  SMMGPHSQP-PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGP 196
               GP   P P G PG  P  P    P  Q G     G       P   GP G    PGP
Sbjct: 1258 GDDGPKGNPGPVGFPG-DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP 1316

Query: 197  --------------QNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSS 242
                          +  G G +  P ++G       +GP      P P+    +P S   
Sbjct: 1317 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1376

Query: 243  PGT-----YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGS 296
             G        GPPG  GPPG P +   A +     +   +    PPG        G PG 
Sbjct: 1377 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1436

Query: 297  DGPMGGMGGMEPHHMNGSLGSGDIDGLP-------------KNSPNNISGISNPPGTPRD 343
             G  G  G M     +G +G G   GLP                P    G+  PPG P  
Sbjct: 1437 QGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1496

Query: 344  DGEL 347
             GE+
Sbjct: 1497 PGEV 1500



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 80/256 (31%), Positives = 93/256 (36%), Gaps = 43/256 (16%)

Query: 98   PSPV-LGNIPPNDGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGV 154
            P P+ L  +P   G  G  G + P    GPPG  P P     P  P+   GP   PPGGV
Sbjct: 1152 PGPIGLQGLPGPSGEKGETGDVGP---MGPPGP-PGPRG---PAGPNGADGPQG-PPGGV 1203

Query: 155  PGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAM 214
                     ++ P  ++G P   GS      P   GP G   +   SG    P   GP  
Sbjct: 1204 --------GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1255

Query: 215  PGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNI 274
            P  + GP  G P P              PG   GPPG GGP G       A      D  
Sbjct: 1256 PTGDDGP-KGNPGP-----------VGFPGD-PGPPGEGGPRG----QDGAKGDRGEDG- 1297

Query: 275  YTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNIS 332
                 P  PG +  N P GP G  GP G  G        G+ G     G P K  P    
Sbjct: 1298 -EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGP---V 1353

Query: 333  GISNPPGTPRDDGELG 348
            G + P G P  DG  G
Sbjct: 1354 GPAGPAGKPGPDGLRG 1369



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 69/243 (28%), Positives = 89/243 (36%), Gaps = 22/243 (9%)

Query: 112  PGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPL--LPNSMDPTR 169
            P GPI P    G  G+   P A+ P  +  +     ++   G PG   L  LP    P+ 
Sbjct: 1109 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPG---PSG 1165

Query: 170  QQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPN 229
            ++G     G +  M PP   GP GP   N   G + PP  +G      N+GP   +  P 
Sbjct: 1166 EKGET---GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG------NLGPPGEKGEPG 1216

Query: 230  PNSANSIPYSSS--SPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSR 287
             + +  I        P    G  G  G PG P  P P   T          NP P G   
Sbjct: 1217 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG---PKGNPGPVGFPG 1273

Query: 288  SNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDG-LPKNSPNNISGISNPPGTPRDDGE 346
               P  PG  GP G  G       +G  G     G   +N P    G   P G+P  +G 
Sbjct: 1274 DPGP--PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGR 1331

Query: 347  LGG 349
             GG
Sbjct: 1332 QGG 1334



 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 83/293 (28%), Positives = 103/293 (35%), Gaps = 65/293 (22%)

Query: 109  DGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP--PG--------GVPG 156
            DG PG  G I     +G  G  P    +  P  P    GP   P  PG        GVPG
Sbjct: 741  DGFPGFKGDIGVKGDRGEVGV-PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 799

Query: 157  TQPLLPNSMDPTRQQGHPNMGGS--------MQRMNPPRG-MGPMGP----GPQ------ 197
              P  P    P    G P   G+        +   + PRG  GP GP    GP+      
Sbjct: 800  L-PGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 858

Query: 198  -----NYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPG 251
                 + G G   PP   G P   G N  PG   P P P   + +P      G  VG  G
Sbjct: 859  GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP-PGPPGKDGLPGHPGQRGE-VGFQG 916

Query: 252  GGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--------------GSRSN--FPMGPG 295
              GPPG P +  P  +   +  +    +P PPG              G++ +   P  PG
Sbjct: 917  KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 976

Query: 296  SDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
             DGP G  G      + G+ G   + G          G S PPG     GE G
Sbjct: 977  KDGPAGLRGFPGERGLPGTAGGPGLKG--------NEGPSGPPGPAGSPGERG 1021



 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 80/270 (29%), Positives = 98/270 (36%), Gaps = 38/270 (14%)

Query: 102  LGNIPPNDGMPGGPIPPGFF-----QGPPGSQPSPHAQPP-----PHNPSSMMGPHSQPP 151
            L   P   G+PG    PG        GPPG   SP  +       P  P    GP   PP
Sbjct: 983  LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG-PP 1041

Query: 152  G-----GVPGTQ-PLLPNSMDPTR-QQGHPNMGGSMQRMNPPRGMGPMG-PGPQNY--GS 201
            G     GVPG + P+ P   D  +   G P   G           G +G PG +      
Sbjct: 1042 GAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNK 1101

Query: 202  GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT--YVGPPGGGGPPGTP 259
            G   PP   GP  P    G       P          +    GT  + GPP   GP G  
Sbjct: 1102 GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP---GPIGLQ 1158

Query: 260  IMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSG 318
             +P P+     + ++  M  P PPG      P GP G+DGP G  GG+      G+LG  
Sbjct: 1159 GLPGPSGEKGETGDVGPMGPPGPPG---PRGPAGPNGADGPQGPPGGV------GNLGPP 1209

Query: 319  DIDGLPKNSPNNISGISNPPGTPRDDGELG 348
               G P  S +   GI   PG     GE G
Sbjct: 1210 GEKGEPGESGS--PGIQGEPGVKGPRGERG 1237



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 70/250 (28%), Positives = 89/250 (35%), Gaps = 41/250 (16%)

Query: 106  PPND-GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPS-----SMMGPHSQP-PGGVPGTQ 158
            PP + G+PG P  P  F GP G    P     P +P         G    P P GV G Q
Sbjct: 872  PPGERGLPG-PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 930

Query: 159  PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGIN 218
                    P  ++GHP   G      PP   G  G   +    G   PP + G       
Sbjct: 931  G-AAGETGPMGERGHPGPPG------PPGEQGLPGTAGKEGTKGDPGPPGAPG------K 977

Query: 219  MGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMI 278
             GP   R +P       +P ++  PG   G  G  GPPG    P    +  S        
Sbjct: 978  DGPAGLRGFP---GERGLPGTAGGPG-LKGNEGPSGPPGPAGSPGERGAAGSG------- 1026

Query: 279  NPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPP 338
             P+ P G        PG  GP G  G        G +G    DG+    P  + G + PP
Sbjct: 1027 GPIGPPGR-------PGPQGPPGAAGEKGVPGEKGPIGPTGRDGV--QGPVGLPGPAGPP 1077

Query: 339  GTPRDDGELG 348
            G   +DG+ G
Sbjct: 1078 GVAGEDGDKG 1087



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 72/253 (28%), Positives = 87/253 (34%), Gaps = 27/253 (10%)

Query: 112 PGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMG-PHSQPPGGVPGTQPLLPNSMDPTRQ 170
           P GP  P    GPPG +     +        M G P  +   G  G  P LP       +
Sbjct: 518 PQGPRGPQGLTGPPG-KAGRRGRAGADGARGMPGDPGVKGDRGFDGL-PGLPG------E 569

Query: 171 QGHPNMGGSMQRMNPPRGMGPMGP----GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRP 226
           +GH    G+     PP   G  G     GP+    G   P   LGP  P    GP   R 
Sbjct: 570 KGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL-PGESGPRGLLGPKGPPGIPGPPGVRG 628

Query: 227 WPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGS 286
              P      P  S  P    GPPG  G PGT  +P P  +            P  PG  
Sbjct: 629 MDGPQG----PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 684

Query: 287 RSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 345
            S+ P G PG +GP G  G   P    G LG           P  + G+    G     G
Sbjct: 685 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG--------YPGPRGVKGVDGIRGLKGHKG 736

Query: 346 ELGGNFLHSFQND 358
           E G +    F+ D
Sbjct: 737 EKGEDGFPGFKGD 749



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 83/268 (30%), Positives = 96/268 (35%), Gaps = 40/268 (14%)

Query: 113  GGPI-PPGFF--QGPPGSQ-----PSPHAQPPPHNPSSMMGPHSQP----PGGVPGTQPL 160
            GGPI PPG    QGPPG+      P       P     + GP   P    P GV G    
Sbjct: 1026 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 1085

Query: 161  LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGP----AMPG 216
                 DP    G     G+     PP   GP+GP  Q   +G    P + GP       G
Sbjct: 1086 KGEVGDP----GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1141

Query: 217  INMGPGAGRPWPNPNSANSIPYSSSSPGTY--VGPPGGGGPPGT--PIMPSPADSTNSSD 272
                 G   P P P     +P  S   G    VGP G  GPPG   P  P+ AD      
Sbjct: 1142 DEGTRGFNGP-PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1200

Query: 273  NIYTMINPV----PPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLG-------SGDI 320
                 + P      PG S S    G PG  GP G  G        G  G       +GD 
Sbjct: 1201 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD- 1259

Query: 321  DGLPKNSPNNISGISNPPGTPRDDGELG 348
            DG PK +P  + G    PG P + G  G
Sbjct: 1260 DG-PKGNPGPV-GFPGDPGPPGEGGPRG 1285



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 79/321 (24%), Positives = 96/321 (29%), Gaps = 89/321 (27%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLP--- 162
           PP    P G I P   QG PG    P  + PP        P S    G PGT  +LP   
Sbjct: 400 PPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL---PGSDGAPGPPGTSLMLPFRF 456

Query: 163 ---------------------------------------NSMDPTRQQGHPNMGGSMQRM 183
                                                      P  Q G P + G    +
Sbjct: 457 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 516

Query: 184 NPPRGMGPMG-PGPQNY--------GSGMRPPPNSLG----------PAMPGI--NMGPG 222
            P    GP G  GP             G R  P   G          P +PG   + G  
Sbjct: 517 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 576

Query: 223 AGRPWPNPNSAN------------SIPYSSSSPGTY--VGPPGGGGPPGTPIMPSPADST 268
             +  P P   +             +P  S   G     GPPG  GPPG   M  P    
Sbjct: 577 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 636

Query: 269 NSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNS 327
            S   +     P PPG   +     PG+ G  G  G + PH   G  G   + G+P  + 
Sbjct: 637 GS---LGPQGEPGPPGQQGT-----PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 688

Query: 328 PNNISGISNPPGTPRDDGELG 348
           P    G   PPGT  + G  G
Sbjct: 689 PPGHPGKEGPPGTKGNQGPSG 709



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 60/207 (28%), Positives = 72/207 (34%), Gaps = 30/207 (14%)

Query: 107  PNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMD 166
            P    P GP  P    GP G +  P +      P +        P G PG  P L     
Sbjct: 1347 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGL-PGLRGDAG 1405

Query: 167  PTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGS--GMRPPPNSLGPAMPGINMG 220
               ++GHP + G +    PP   G  G    PGPQ      G    P + GP  PG   G
Sbjct: 1406 AKGEKGHPGLIGLI---GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPG---G 1459

Query: 221  PGAGRPWP-NPNSANSIPYSSSSPGT--YVGPPGGGGPPGTPIMPSPADSTNSS------ 271
            P  G P P  P  A          G     GPPG  GPPG  I P P      +      
Sbjct: 1460 P-PGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDG 1518

Query: 272  DNIYTMINPVPPGGSRSNFPMGPGSDG 298
              +      +P GG+       PGS G
Sbjct: 1519 SRLMQEDEAIPTGGA-------PGSPG 1538



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 74/282 (26%), Positives = 93/282 (32%), Gaps = 64/282 (22%)

Query: 123 GPPGSQPSPHAQPPPHNPSSMMGPHSQP----PG----GVPGTQPLLPNSMDPTRQQGHP 174
           GP  S  + H+    H P  + G   +P    PG    G PG +      + P   QG+P
Sbjct: 361 GPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEG-PAGLIGPPGIQGNP 419

Query: 175 NMGGSMQRMNPPRGMGPMG----PGPQ--------NYGSG-------------------- 202
              G      PP   G  G    PGP          +GSG                    
Sbjct: 420 GPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 479

Query: 203 -----MRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPP 256
                +R PP  +G    PG    PG+  P     S +  P     P    GPPG  G  
Sbjct: 480 QARLALRGPPGPMGYTGRPGPLGQPGS--PGLKGESGDLGPQGPRGPQGLTGPPGKAGRR 537

Query: 257 GTP----IMPSPADSTNSSDNIYTMINPVP-PGGSRSN-----FPMGPGSDGPMGGMGGM 306
           G          P D     D  +  +  +P   G R +      P  PG DG  G  G +
Sbjct: 538 GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 597

Query: 307 EPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            P  + G  G   + G PK  P    GI  PPG    DG  G
Sbjct: 598 GPRGLPGESGPRGLLG-PKGPP----GIPGPPGVRGMDGPQG 634



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 71/316 (22%), Positives = 86/316 (27%), Gaps = 81/316 (25%)

Query: 124 PPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPG---------------TQPLLPNSMDPT 168
           P   QP    + P   PS +  P +Q P   P                T    P+  DPT
Sbjct: 236 PQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQPTESLYYDYEPPYYDVMTTGTTPDYQDPT 295

Query: 169 RQQGHPNMGGSM---------QRMNPPR---------GMG----PMGPGPQNYGSG-MRP 205
             +    +  S+             PP          G G    P GP    YG G    
Sbjct: 296 PGEEEEILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYR 355

Query: 206 PPNSLGPAMPGINMGPGAGRPWP-------------NPNSANSIPYSSSSPGTYVGPPGG 252
               LGPA+       GA    P              P      P     P   +GPPG 
Sbjct: 356 EETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGI 415

Query: 253 GGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGS--------RSNFPMGP---------- 294
            G PG    P        +    +   P PPG S              GP          
Sbjct: 416 QGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQ 475

Query: 295 -----------GSDGPMGGMGGMEPHHMNGSLG-SGDIDGLPKNSPNNISGISNPPGTPR 342
                      G  GPMG  G   P    GS G  G+   L    P    G++ PPG   
Sbjct: 476 AILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAG 535

Query: 343 DDGELGGNFLHSFQND 358
             G  G +       D
Sbjct: 536 RRGRAGADGARGMPGD 551


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 79/256 (30%), Positives = 95/256 (37%), Gaps = 25/256 (9%)

Query: 100  PVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGT-- 157
            P L   P N G+ G    PG     PG   +P A+  P  P     P    P G+ G   
Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGL----PGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1140

Query: 158  QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGI 217
             P LP    P    GHP   G       P   G  GP  Q    G     N   P +PG+
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 218  NMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTM 277
            +   G G   P       +P     PG + G PG  GPPG P  P PA            
Sbjct: 1201 SGQKGDG-GLPGIPGNPGLPGPKGEPG-FHGFPGVQGPPGPPGSPGPALEGPKG------ 1252

Query: 278  INPVPPG-GSRSNFPMGPGSDGPMG--GMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGI 334
             NP P G   R  F   PG +GP G  G GG++     G+ G   + GLP      + G 
Sbjct: 1253 -NPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGE--KGNPGQPGLPGLP-----GLKGD 1304

Query: 335  SNPPGTPRDDGELGGN 350
              PPG   + G  G N
Sbjct: 1305 QGPPGLQGNPGRPGLN 1320



 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 89/276 (32%), Positives = 111/276 (40%), Gaps = 63/276 (22%)

Query: 102  LGNIPPNDGMPGGPIPPGFF-----QGPPG--SQPSPHAQPPPHNPSSMMGPHSQP--PG 152
            L  IP N G+PG    PGF      QGPPG    P P  + P  NP    GP   P  PG
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP----GPQGPPGRPG 1264

Query: 153  --GVPGTQ--PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPN 208
              G+PG +  P LP +     ++G+P   G       P   G  GP P   G+  RP  N
Sbjct: 1265 FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLP---GLPGLKGDQGP-PGLQGNPGRPGLN 1320

Query: 209  SL--GPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPAD 266
             +   P +PG+   PG   P   P SA              G PG  GPPG P +P P  
Sbjct: 1321 GMKGDPGLPGVPGFPGMKGPSGVPGSAGP-----------EGEPGLIGPPGPPGLPGP-- 1367

Query: 267  STNSSDNIYTMINPVPPG-----GSRS----NFPMG-PGSDGPMG-----------GMGG 305
               S  +I    +  PPG     G +       P G PG  GP G           G GG
Sbjct: 1368 ---SGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1424

Query: 306  ME-PHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 340
             +    + G  G+  +DG P   P+ + G   PPGT
Sbjct: 1425 RKGDPGLPGQPGTRGLDGPP--GPDGLQGPPGPPGT 1458



 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 79/254 (31%), Positives = 100/254 (39%), Gaps = 39/254 (15%)

Query: 110 GMPGGPIPPGFFQGPPG--SQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQ--PLLPNSM 165
           G+PG P P    +GPPG   Q      P P  P  + GP   P  G PGT   P +P   
Sbjct: 60  GLPGFPGP----EGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP--GFPGTPGLPGMPGHD 113

Query: 166 DPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRPPPNSL-GPAMPGINMG 220
                QG P   G+      P   G  G    PGP     GM+  P S+   ++PG    
Sbjct: 114 GAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI-PGMKGEPGSIIMSSLPGPKGN 172

Query: 221 PGAGRPWPNPNSANSIPYSSSSPGTY--VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMI 278
           PG    +P P     +P  +  PG     GPPG  GPPG P +P P  +          +
Sbjct: 173 PG----YPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMG--------L 220

Query: 279 NPVPPGGSRSNFPMGPGSDGPMGGMGGM--EPHHMNGSLGSGDIDGLP-KNSPNNISGIS 335
           N   P G +       G  GP G  G +  +   ++     GD  GLP    P    GI 
Sbjct: 221 NFQGPKGEKGE----QGLQGPPGPPGQISEQKRPIDVEFQKGD-QGLPGDRGPPGPPGIR 275

Query: 336 NPPGTP-RDDGELG 348
            PPG P  + GE G
Sbjct: 276 GPPGPPGGEKGEKG 289



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 96/310 (30%), Positives = 115/310 (37%), Gaps = 66/310 (21%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPPG-----FFQGPPGSQPSPHAQPPPHNPSSMMGPH 147
           S  A   P L   P  DG+PG P P G      F+G  G   +P     P N   M  P 
Sbjct: 565 SPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624

Query: 148 SQPPG--------GVPGT--QPLLPNSM-DPTR---QQGHPNMGGSMQRMNPPRGMGPMG 193
             PPG        GV G   QP +P    DP +   Q G P + G     NP R  G +G
Sbjct: 625 FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG-----NPGRD-GDVG 678

Query: 194 -PGPQNYGS--GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP 249
            PG        G+   P S G P +PGI + PG     P P     IP    +PGT  G 
Sbjct: 679 LPGDPGLPGQPGLPGIPGSKGEPGIPGIGL-PGP----PGPKGFPGIPGPPGAPGT-PGR 732

Query: 250 PGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG-----------GSRSNFPMGPGS-- 296
            G  GPPG P  P P               P PPG           G R  FP  PG   
Sbjct: 733 IGLEGPPGPPGFPGP----KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGPPGPPG 787

Query: 297 ----DGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFL 352
               DG  G  G + P+   G +G   + G+       + G   PPG P   G +G   L
Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI------GVQGPPGPPGIP---GPIGQPGL 838

Query: 353 HSFQNDNYSP 362
           H    +   P
Sbjct: 839 HGIPGEKGDP 848



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 85/281 (30%), Positives = 103/281 (36%), Gaps = 45/281 (16%)

Query: 106 PPNDGMPG-----GPI-PPGFFQGPPGSQPSPHAQPPPHNPSS--MMGPHSQP------P 151
           P N G+PG     GP+ PPGF  GPPG       Q    NP    + GP   P      P
Sbjct: 605 PGNPGLPGLPGNIGPMGPPGF--GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQP 662

Query: 152 G--GVPGTQPL-----LPNSMDPTRQQGHPNMGGSMQRMNPPRGMG-PMGPGPQNYGSGM 203
           G  G+PG         LP       Q G P + GS      P G+G P  PGP+ +  G+
Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIP-GIGLPGPPGPKGF-PGI 720

Query: 204 RPPPNSLG-PAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGT--------------YV 247
             PP + G P   G+   PG  G P P      ++P     PG               + 
Sbjct: 721 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 780

Query: 248 GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGME 307
           GPPG  G  G   +P P      +     M  P  PG      P  PG  GP+G  G   
Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG--- 837

Query: 308 PHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            H + G  G     GL    P    G    PG P   G  G
Sbjct: 838 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG 878



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 87/314 (27%), Positives = 102/314 (32%), Gaps = 79/314 (25%)

Query: 103  GNIPPNDGMPGGPIPPGF----FQGPPGSQ--PSPHAQPPPHNPSSMMGPHSQPPGGVPG 156
            G++ PN G PG   PPG      QGPPG    P P  QP  H      G    P   VPG
Sbjct: 799  GDVGPN-GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPG 857

Query: 157  T-----QPLLPNSMDPTRQQGHPNMGGS------------MQRMNPPRGMGPMG------ 193
                   P +P +  P    G P + G             M  M PP   GP+G      
Sbjct: 858  PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917

Query: 194  ----------------PGPQNYGSGMRPP----------PNSLG-------PAMPGINMG 220
                            PGP         P          PN LG       P +PGI   
Sbjct: 918  VPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI--- 974

Query: 221  PGAGRPWPNPNSANSIPYSSSSPGT-----YVGPPGGGGPPGTPIMPSPADSTNSSDNIY 275
            PG       P     +P     PG        GPPG  G PG P  P           I 
Sbjct: 975  PGVS----GPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 276  TMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGI 334
             M  P P G      P G PG  G   G+ G +    +  + S  + GLP   P    G+
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPG-SPGLPGQKGDKGDPGISSIGLPGLP--GPKGEPGL 1087

Query: 335  SNPPGTPRDDGELG 348
               PG P   G +G
Sbjct: 1088 PGYPGNPGIKGSVG 1101



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 88/304 (28%), Positives = 98/304 (32%), Gaps = 73/304 (24%)

Query: 106  PPND-GMPGGPIPPGFFQGPPGSQPSPHAQ-----PPPHNPSSMMGPHSQP-PGGVPGTQ 158
            PP + G PG P  PG   GPPGS   P        P       MMGP   P P G+PG  
Sbjct: 858  PPGERGSPGIPGAPGPI-GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 159  --PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYGS-------------G 202
              P L        Q G P   G       P   GP GP  P   GS             G
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 203  MRPPPNSLG----PAMPGINMGPGAGRPWPNPNSANSIPYSSS----------------- 241
            +  P    G    P  PG++  PG   P P P     +P                     
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGP-PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 242  SPGTYVGPPGGGGPPGTPIMPS-PADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 300
             P    GPPG  G PG P  P  P    +  D          PG S    P  PG  G  
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD----------PGISSIGLPGLPGPKGEP 1085

Query: 301  GGMGGMEPHHMNGSLGSGDIDGLPKN----------------SPNNISGISNPPGTPRDD 344
            G  G      + GS+G   + GLP                   P    GIS PPG P   
Sbjct: 1086 GLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145

Query: 345  GELG 348
            GE G
Sbjct: 1146 GEPG 1149



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 81/295 (27%), Positives = 98/295 (33%), Gaps = 61/295 (20%)

Query: 99  SPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-------- 150
           S ++ ++P   G PG P PPG  QG PG    P    PP  P  +MGP   P        
Sbjct: 160 SIIMSSLPGPKGNPGYPGPPG-IQGLPGPTGIPGPIGPP-GPPGLMGPPGPPGLPGPKGN 217

Query: 151 -------------------PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGP 191
                              P G PG        +D   Q+G   + G      PP   GP
Sbjct: 218 MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 192 MG-PGPQNYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP 249
            G PG +    G +  P   G P   G N  PG             IP     PG Y G 
Sbjct: 278 PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------IPGLPGDPG-YPGE 323

Query: 250 P---------GGGGPPGTP--IMPSPADSTNSSDNIYTMINPVPPGGSRSNFP---MGPG 295
           P         G  GPPG P  ++P P       +     +  +P       FP     PG
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383

Query: 296 SDGPMGG--MGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
             GP G   MG   P    G  G    +G P  S     G+   PG P   G  G
Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG 438



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 82/283 (28%), Positives = 98/283 (34%), Gaps = 47/283 (16%)

Query: 94  AAAAPSPVLGNIPPNDGMPGGPIPPGF-FQGPPG--SQPSPHAQPPPHNPSSMMGPHSQP 150
           AA    P     P   G  G   PPG    GPPG   QP     P P  P+   GPH  P
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA---GPHIPP 446

Query: 151 PGGV--PGTQPLLPNSMDPTRQQGHPNMGGSM-QRMNPPRGMGPMGPGPQNYGSGMRPPP 207
              +  PG  P  P S      QG   + G          G G  GP  Q    G+  PP
Sbjct: 447 SDEICEPGP-PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 208 NSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPAD 266
            SLG P   G     GA      P     IP +  +PG     PG  G PG  I+  P  
Sbjct: 506 GSLGFPGQKGEKGQAGA----TGPKGLPGIPGAPGAPGF----PGSKGEPGD-ILTFPGM 556

Query: 267 STNSSDNIYTMINPVPPGGSRSNFPMGPGSDG------PMGGMGGMEPHHMNGSLGSGDI 320
             +  +    + +P  PG      P  PG DG      P G  GG+      G  G+  +
Sbjct: 557 KGDKGE----LGSPGAPG--LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610

Query: 321 DGLPKN---------------SPNNISGISNPPGTPRDDGELG 348
            GLP N                   I G++  PG P   G  G
Sbjct: 611 PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKG 653



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 59/189 (31%), Positives = 70/189 (37%), Gaps = 30/189 (15%)

Query: 171 QGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRPPPNSLG----PAMPGINMGPG 222
           +GHP + G      PP   G  G    PGP     G+R PP   G    P +PG+    G
Sbjct: 56  EGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPG-PKGIRGPPGLPGFPGTPGLPGMPGHDG 114

Query: 223 AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVP 282
           A  P   P   N        PG+  G PG  GPPG P +P       S   I     P P
Sbjct: 115 APGPQGIPG-CNGTKGERGFPGS-PGFPGLQGPPGPPGIPGMKGEPGS---IIMSSLPGP 169

Query: 283 PGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPR 342
            G         PG  GP G  G   P  + G +G           P  + G   PPG P 
Sbjct: 170 KGN--------PGYPGPPGIQGLPGPTGIPGPIGPP--------GPPGLMGPPGPPGLPG 213

Query: 343 DDGELGGNF 351
             G +G NF
Sbjct: 214 PKGNMGLNF 222



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 79/275 (28%), Positives = 98/275 (35%), Gaps = 57/275 (20%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSM 165
           P   G+ G P PPG  +G  G Q  P  +  P       G + QP  G+PG    LP   
Sbjct: 269 PGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD----GENGQP--GIPG----LPGDP 318

Query: 166 DPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQ---------NYG-------------SGM 203
               + G     G      PP   G + P P          N G              G+
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI 378

Query: 204 RPPPNSLGPAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP 262
           + PP   GP    +   PG  G P       +  P   S PG    PPG  G PG P +P
Sbjct: 379 QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG----PPGLDGQPGAPGLP 434

Query: 263 SPADSTN----SSDNIYTMINPVPPGGSRSNFPMGPGSDGPMG--GMGGMEPHHMNGSLG 316
            P          SD I     P PPG      P  PG  G  G  G+ G +       +G
Sbjct: 435 GPPGPAGPHIPPSDEI---CEPGPPGP-----PGSPGDKGLQGEQGVKGDKGDTCFNCIG 486

Query: 317 SGDIDGLPKNSPNNISGISNPPGT---PRDDGELG 348
           +G I G P   P  + G+  PPG+   P   GE G
Sbjct: 487 TG-ISG-PPGQP-GLPGLPGPPGSLGFPGQKGEKG 518



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/124 (31%), Positives = 44/124 (35%), Gaps = 10/124 (8%)

Query: 248 GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--GSRS-----NFPMGPGSDGPM 300
           G PG  G PG P  P P               P PPG  G R       FP  PG  G  
Sbjct: 51  GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMP 110

Query: 301 GGMGGMEPHHMNGSLGSGDIDGLPKNSPN--NISGISNPPGTPRDDGELGGNFLHSFQND 358
           G  G   P  + G  G+    G P  SP    + G   PPG P   GE G   + S    
Sbjct: 111 GHDGAPGPQGIPGCNGTKGERGFP-GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169

Query: 359 NYSP 362
             +P
Sbjct: 170 KGNP 173


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 81/280 (28%), Positives = 97/280 (34%), Gaps = 56/280 (20%)

Query: 110 GMPG--GPIPPGFFQGPPGSQP-----SPHAQPPPHNPS-----------SMMGPHSQPP 151
           G PG  GPI P   QGPPG +       P A   P  P             + GP   P 
Sbjct: 238 GFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG 297

Query: 152 GGVPGTQPL--------LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGM 203
            G PG   L        LP       +QG   + G      PP  MGP GP       G+
Sbjct: 298 FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGL 357

Query: 204 RPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPS 263
             P    GPA P       AG  +P        P S   PG Y G PG  GP G P +P 
Sbjct: 358 PGPKGETGPAGP-------AG--YPGAKGERGSPGSDGKPG-YPGKPGLDGPKGNPGLPG 407

Query: 264 PADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGL 323
           P            +  PV P G++      PG +G  G  G        G +G   I G 
Sbjct: 408 PKGDPGVG-GPPGLPGPVGPAGAKGM----PGHNGEAGPRGAPGIPGTRGPIGPPGIPGF 462

Query: 324 P--KNSPNN-------------ISGISNPPGTPRDDGELG 348
           P  K  P +             ++G + PPG P   G  G
Sbjct: 463 PGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSG 502



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 88/287 (30%), Positives = 100/287 (34%), Gaps = 63/287 (21%)

Query: 91  DYSAAAAPSPVLGNIPPNDGMPGGPIPPGF-FQGPPGSQ-----PSPHAQPPPHNPSSMM 144
           D   A  P P     PP  G PG P P G    G PG Q     P P   P       + 
Sbjct: 128 DVGPAGLPGP---RGPP--GPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVP 182

Query: 145 GPHSQPPG---GVPGT--QPLLPNSMDPTRQQGHPNMGGSMQRMNP-----------PRG 188
           G + Q      G PG   +  LP    PT   G P +G   +   P           P  
Sbjct: 183 GMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGE 242

Query: 189 MGPMG-PGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT-- 245
           MGP+G PGPQ        PP   GP         G G+P      A   P     PGT  
Sbjct: 243 MGPIGPPGPQG-------PPGERGP--------EGIGKP-----GAAGAPGQPGIPGTKG 282

Query: 246 YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG----PGSDGPMG 301
             G PG  GPPG P    P       +     + P  PG      P G    PG  GP G
Sbjct: 283 LPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGL-PGGPGAKGEQGPAGLPGKPGLTGPPG 341

Query: 302 GMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            MG   P  + GS       GLP   P   +G + P G P   GE G
Sbjct: 342 NMGPQGPKGIPGS------HGLP--GPKGETGPAGPAGYPGAKGERG 380



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 79/256 (30%), Positives = 90/256 (35%), Gaps = 53/256 (20%)

Query: 96  AAPSPVLGNIPPNDGMPGGPI------PPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQ 149
           AA +P    IP   G+PG P       PPGF  G PG       + P   P        Q
Sbjct: 268 AAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF--GKPGLPGLKGERGPAGLPGGPGAKGEQ 325

Query: 150 PPGGVPGTQPLL--PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPP 207
            P G+PG   L   P +M P   +G P   GS     P    GP GP       G R  P
Sbjct: 326 GPAGLPGKPGLTGPPGNMGPQGPKGIP---GSHGLPGPKGETGPAGPAGYPGAKGERGSP 382

Query: 208 NSLG----------------PAMPGINMGPGAGRPWP-----NPNSANSIPYSSSS---- 242
            S G                P +PG    PG G P        P  A  +P  +      
Sbjct: 383 GSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPR 442

Query: 243 -----PGTY--VGPPG------GGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG-GSRS 288
                PGT   +GPPG        G PG+P  P PA       N  T   P PPG    S
Sbjct: 443 GAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTG-PPGPPGPRGHS 501

Query: 289 NFPMGPGSDGPMGGMG 304
             P  PG  GP G  G
Sbjct: 502 GEPGLPGPPGPPGPPG 517



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 61/180 (33%), Positives = 73/180 (40%), Gaps = 30/180 (16%)

Query: 105 IPPNDGMPG-----GPIPPGFFQGPPGSQPSPHAQPPPHNPSS--MMGPHSQP----PGG 153
           IP + G+PG     GP  P  + G  G + SP +   P  P    + GP   P    P G
Sbjct: 351 IPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKG 410

Query: 154 VPGT--QPLLPNSMDPTRQQGHPNMGGSM-QRMNP--PRGMGPMGPG-----PQNYGSGM 203
            PG    P LP  + P   +G P   G    R  P  P   GP+GP      P + G   
Sbjct: 411 DPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPG 470

Query: 204 RP-PPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP 262
            P PP   G A  G+N   G   P P P         S  PG   GPPG  GPPG  +MP
Sbjct: 471 SPGPPGPAGIATKGLNGPTGPPGP-PGPRG------HSGEPGL-PGPPGPPGPPGQAVMP 522



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 80/247 (32%), Positives = 97/247 (39%), Gaps = 41/247 (16%)

Query: 123 GPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQ--PLLPNSMDPTR--QQGHPNMGG 178
           GPPG    P   P P       GP  +P  G PG Q  P LP    P+   + G P + G
Sbjct: 63  GPPGPA-GPRGHPGPS------GPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPG 115

Query: 179 SMQRMNP--PRG-MGPMG-PGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRP-------- 226
                 P  P+G +GP G PGP+    G   PP   GPA   +   PG   P        
Sbjct: 116 KPGERGPYGPKGDVGPAGLPGPR----GPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRG 171

Query: 227 WPNPNSANSIPYSSSSPGTY-VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVP--P 283
           +P    A  +P  +   G    G PG  G  G P    P   +          N VP  P
Sbjct: 172 FPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQP 231

Query: 284 G--GSRSNFP--MGP-GSDGPMGGMGGMEPHHMN--GSLGSGDIDGLP--KNSPNNISGI 334
           G  G R  FP  MGP G  GP G  G   P  +   G+ G+    G+P  K  P    GI
Sbjct: 232 GIKGDR-GFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP-GAPGI 289

Query: 335 SNPPGTP 341
           + PPG P
Sbjct: 290 AGPPGPP 296



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 58/178 (32%), Positives = 67/178 (37%), Gaps = 32/178 (17%)

Query: 178 GSMQRMNPPRGMGPMG-PGPQNYGSGMRPPPNSLGPAMPGINMGPGA-GRPWPNPNSANS 235
           G      PP   GP G PGP         PP   G   PG+   PG  G P P+      
Sbjct: 57  GEQGTPGPPGPAGPRGHPGPSG-------PPGKPGYGSPGLQGEPGLPGPPGPSAVGKPG 109

Query: 236 IPYSSSSPGTY--------VGP---PGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG 284
           +P     PG          VGP   PG  GPPG P +P PA        I     P   G
Sbjct: 110 VPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPA-------GISVPGKPGQQG 162

Query: 285 GSRSNFPMG-PGSDGPMG--GMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPG 339
            + +  P G PG  G  G  GM G +     G+ G     GLP   P   +G S PPG
Sbjct: 163 PTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLP--GPQGPTGPSGPPG 218



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 48/161 (29%), Positives = 57/161 (35%), Gaps = 21/161 (13%)

Query: 219 MGPGAGRPWPNPNSANSIPYSSSSPGTYV-------GPPGGGGPPGTPIMPSPADSTN-S 270
           M  G   P PN  +   IPY+  S G  V       GPPG  GP G P    P       
Sbjct: 27  MPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYG 86

Query: 271 SDNIYTMIN-PVPPGGSR------SNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGL 323
           S  +      P PPG S          P  PG  GP G  G + P  + G  G     G+
Sbjct: 87  SPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI 146

Query: 324 PKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNYSPSM 364
           P   P  IS     PG P   G  G      F  +  +P +
Sbjct: 147 P--GPAGIS----VPGKPGQQGPTGAPGPRGFPGEKGAPGV 181


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 79.0 bits (193), Expect = 6e-15
 Identities = 80/266 (30%), Positives = 94/266 (35%), Gaps = 41/266 (15%)

Query: 106  PPNDGMPGGPIPPGFF-----------QGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGV 154
            P ++G PG P PPG              GPPG    P  Q P   P     P    P G 
Sbjct: 908  PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA 967

Query: 155  PGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNY--GSGMRPPPNSLG 211
             G     P       Q+G   + G       P   GP G PG Q     SG R PP  +G
Sbjct: 968  EGP----PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 1023

Query: 212  P-------AMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSP 264
            P         PG    PGA  P P  + A  +       G  VG PG  GPPG+   P P
Sbjct: 1024 PPGLTGPAGEPGREGSPGADGP-PGRDGAAGVKGDRGETGA-VGAPGAPGPPGS---PGP 1078

Query: 265  ADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSGDIDGL 323
            A  T    +          G + +  PMGP G  G  G  G   P    G  G     GL
Sbjct: 1079 AGPTGKQGD---------RGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL 1129

Query: 324  PKNSP-NNISGISNPPGTPRDDGELG 348
              +     + G+  PPG   D G  G
Sbjct: 1130 KGHRGFTGLQGLPGPPGPSGDQGASG 1155



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 84/287 (29%), Positives = 100/287 (34%), Gaps = 45/287 (15%)

Query: 95  AAAPSP--VLGNIPPNDGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP 150
           A AP P    GN P   G PG  GP+ P    GPPG          P        P  Q 
Sbjct: 215 AGAPGPQGFQGN-PGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 273

Query: 151 PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPR------------GMGPMGP---- 194
             G PGT P LP        +G+P + G+      P               GPMGP    
Sbjct: 274 ARGFPGT-PGLPGVKG---HRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 329

Query: 195 ------GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVG 248
                 GP    +G R      GPA P   +GP  G  +P    A       + P    G
Sbjct: 330 GERGRTGPAG-AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK----GEAGPTGARG 384

Query: 249 PPGGGGP---PGTPIMPSPADSTNS--SDNIYTMINP--VPPGGSRSNFPMGPGSDGPMG 301
           P G  GP   PGTP  P PA ++ +  +D I         P       FP   G  GP G
Sbjct: 385 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 444

Query: 302 GMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
             G + P    G  G     G  +  P    G + P G P   GE G
Sbjct: 445 ATGPLGPKGQTGEPGIAGFKG--EQGPKGEPGPAGPQGAPGPAGEEG 489



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 80/286 (27%), Positives = 93/286 (32%), Gaps = 42/286 (14%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQP--PG- 152
           P+   GN P  DG+PG     G     G PG  P P   P P   +  +GP  Q   PG 
Sbjct: 403 PAGASGN-PGTDGIPGAKGSAGAPGIAGAPGF-PGPRGPPGPQGATGPLGPKGQTGEPGI 460

Query: 153 -GVPGTQPLL--PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNS 209
            G  G Q     P    P    G     G       P G+GP+GP  +    G R  P  
Sbjct: 461 AGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQ 520

Query: 210 LGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT-----YVGPPGGGGP--------- 255
            G A P    G         P  AN  P     PG        G PG  GP         
Sbjct: 521 DGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGA 580

Query: 256 PGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-------------PGSDGPMGG 302
           PG    P P     +      M  P P G +      G             PG DG  G 
Sbjct: 581 PGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGA 640

Query: 303 MGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            G   P    G  G     G P   P+   G+  PPG P + G+ G
Sbjct: 641 AG---PPGPAGPAGERGEQGAP--GPSGFQGLPGPPGPPGEGGKPG 681



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 82/296 (27%), Positives = 104/296 (35%), Gaps = 73/296 (24%)

Query: 110 GMPGG--PIPPGFFQGPPGSQ--------PSPHAQPPPHNPSSMMGPHSQ--PPG----- 152
           G PGG  PI P   +G PG++          P   P    PS + GP      PG     
Sbjct: 495 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 554

Query: 153 GVPGTQPLL--PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-------PGPQNYGSGM 203
           G+PG + L   P    P  + G     G   R  PP   G  G       PGP+    G 
Sbjct: 555 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK----GA 610

Query: 204 RPPPNSLG----PAMPGINMGPG-------AGRPWPNPNSANSIPYSSSSPGTYVG---- 248
              P   G    P  PG+   PG       AG P P   +       +  P  + G    
Sbjct: 611 NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 670

Query: 249 --PPGGGGPPGTPIMPSPADSTNSSDNIYTMINP----------VPPGGSRSNFPMG--- 293
             PPG GG PG   +P  A +         ++ P            PG      P G   
Sbjct: 671 PGPPGEGGKPGDQGVPGEAGAPG-------LVGPRGERGFPGERGSPGAQGLQGPRGLPG 723

Query: 294 -PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            PG+DGP G  G   P    G+ G   + G+P       +GI+ P G   D GE G
Sbjct: 724 TPGTDGPKGASGPAGP---PGAQGPPGLQGMP--GERGAAGIAGPKGDRGDVGEKG 774



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 80/304 (26%), Positives = 96/304 (31%), Gaps = 66/304 (21%)

Query: 102  LGNIPPNDGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHS-------QPPG 152
            L   P  DG  G  GP  P   QGPPG Q      P     + + GP         + P 
Sbjct: 721  LPGTPGTDGPKGASGPAGPPGAQGPPGLQ----GMPGERGAAGIAGPKGDRGDVGEKGPE 776

Query: 153  GVPG-------TQPLLP----NSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYG 200
            G PG       T P+ P     +     + G P   GS      P   G  GP GP  + 
Sbjct: 777  GAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 836

Query: 201  S--------------------------GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSAN 234
                                       G + P  + GP  P    GP   R    P  A 
Sbjct: 837  GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 896

Query: 235  SIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG- 293
              P ++      VGPPG  G PG P  P P+              P   G      P G 
Sbjct: 897  GFPGAAGR----VGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 952

Query: 294  ------PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGISNPPGTPRDDGE 346
                  PG DGP G  G   P  + G  G   I GLP +       G+  P G P   G 
Sbjct: 953  PGEKGEPGDDGPSGAEGPPGPQGLAGQRG---IVGLPGQRGERGFPGLPGPSGEPGKQGA 1009

Query: 347  LGGN 350
             G +
Sbjct: 1010 PGAS 1013



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 79/284 (27%), Positives = 96/284 (33%), Gaps = 69/284 (24%)

Query: 109  DGMPGGPIPPGFFQGP---PGSQPSPHAQPPP--HNPSSMMGPHSQPPG-GVPGTQ--PL 160
            D  P GP+ P    GP   PG + SP A  PP     + + G   +    G PG    P 
Sbjct: 1015 DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPG 1074

Query: 161  LPNSMDPTRQQGHPNMGGSMQRMNP--PRG----MGPMGPG--------PQNYG------ 200
             P    PT +QG     G+   M P  P G     GP GP         P   G      
Sbjct: 1075 SPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRG 1134

Query: 201  ----SGMRPPPNSLGPAMPGINMGPGAGRPWPNP------NSANSIPYSSSSPGTY---- 246
                 G+  PP   G        GP   R  P P      + AN IP     PG      
Sbjct: 1135 FTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSG 1194

Query: 247  ----VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFP-MGPGSDGPMG 301
                 GPPG  GPPG P                    P  PG   S F  +GP   GP  
Sbjct: 1195 ETGPAGPPGNPGPPGPP-------------------GPPGPGIDMSAFAGLGPREKGP-D 1234

Query: 302  GMGGMEPHHMNGSLGSGD--IDGLPKNSPNNISGISNPPGTPRD 343
             +  M      G L   D  +D   K+  N I  I +P G+ ++
Sbjct: 1235 PLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKN 1278



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 73/290 (25%), Positives = 90/290 (31%), Gaps = 48/290 (16%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSM 165
           PP    P G   P   +G  G + +P  +     P +   P    P G PG  P L  + 
Sbjct: 121 PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG-PPGLGGNF 179

Query: 166 DPTRQQGHPNMGGSMQRMNPPRGMGPMG----------PGPQNYGSGMRPP--PNSLGPA 213
                 G     G  Q       MGPMG          PGPQ +      P  P   GP 
Sbjct: 180 AAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM 239

Query: 214 MPGINMGP--------GAGRPW-------PNPNSANSIPYSSSSPGT-----YVGPPGGG 253
            P    GP         AG+P        P P  A   P +   PG      Y G  G  
Sbjct: 240 GPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAK 299

Query: 254 GPPGTPIMPSPADSTNSSDNIYTM-----------INPVPPGGSRSN--FPMGPGSDGPM 300
           G  G P +   + S   + +   M             P    G+R N   P   G  GP+
Sbjct: 300 GEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPV 359

Query: 301 GGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGN 350
           G  GG  P         G+        P    G    PGTP   G  G +
Sbjct: 360 GPAGG--PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS 407



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 53/167 (31%), Positives = 60/167 (35%), Gaps = 17/167 (10%)

Query: 190 GPMG----PGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT 245
           GP G    PG      G + PP   GP  P    GP   R       A         PGT
Sbjct: 101 GPKGQKGEPGDIKDIVGPKGPP---GPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157

Query: 246 YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNF---PMGP-GSDGPMG 301
               PG  GPPG P  P P     +             GG++      PMGP G  GP G
Sbjct: 158 ----PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 213

Query: 302 GMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
             G   P    G+ G     G+  + P    G   PPG P DDGE G
Sbjct: 214 PAGAPGPQGFQGNPGEPGEPGV--SGPMGPRGPPGPPGKPGDDGEAG 258


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 79.0 bits (193), Expect = 6e-15
 Identities = 80/266 (30%), Positives = 94/266 (35%), Gaps = 41/266 (15%)

Query: 106  PPNDGMPGGPIPPGFF-----------QGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGV 154
            P ++G PG P PPG              GPPG    P  Q P   P     P    P G 
Sbjct: 839  PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA 898

Query: 155  PGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNY--GSGMRPPPNSLG 211
             G     P       Q+G   + G       P   GP G PG Q     SG R PP  +G
Sbjct: 899  EGP----PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 954

Query: 212  P-------AMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSP 264
            P         PG    PGA  P P  + A  +       G  VG PG  GPPG+   P P
Sbjct: 955  PPGLTGPAGEPGREGSPGADGP-PGRDGAAGVKGDRGETGA-VGAPGAPGPPGS---PGP 1009

Query: 265  ADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSGDIDGL 323
            A  T    +          G + +  PMGP G  G  G  G   P    G  G     GL
Sbjct: 1010 AGPTGKQGD---------RGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL 1060

Query: 324  PKNSP-NNISGISNPPGTPRDDGELG 348
              +     + G+  PPG   D G  G
Sbjct: 1061 KGHRGFTGLQGLPGPPGPSGDQGASG 1086



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 84/287 (29%), Positives = 100/287 (34%), Gaps = 45/287 (15%)

Query: 95  AAAPSP--VLGNIPPNDGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP 150
           A AP P    GN P   G PG  GP+ P    GPPG          P        P  Q 
Sbjct: 146 AGAPGPQGFQGN-PGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 204

Query: 151 PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPR------------GMGPMGP---- 194
             G PGT P LP        +G+P + G+      P               GPMGP    
Sbjct: 205 ARGFPGT-PGLPGVKG---HRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 260

Query: 195 ------GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVG 248
                 GP    +G R      GPA P   +GP  G  +P    A       + P    G
Sbjct: 261 GERGRTGPAG-AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK----GEAGPTGARG 315

Query: 249 PPGGGGP---PGTPIMPSPADSTNS--SDNIYTMINP--VPPGGSRSNFPMGPGSDGPMG 301
           P G  GP   PGTP  P PA ++ +  +D I         P       FP   G  GP G
Sbjct: 316 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 375

Query: 302 GMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
             G + P    G  G     G  +  P    G + P G P   GE G
Sbjct: 376 ATGPLGPKGQTGEPGIAGFKG--EQGPKGEPGPAGPQGAPGPAGEEG 420



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 80/286 (27%), Positives = 93/286 (32%), Gaps = 42/286 (14%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQP--PG- 152
           P+   GN P  DG+PG     G     G PG  P P   P P   +  +GP  Q   PG 
Sbjct: 334 PAGASGN-PGTDGIPGAKGSAGAPGIAGAPGF-PGPRGPPGPQGATGPLGPKGQTGEPGI 391

Query: 153 -GVPGTQPLL--PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNS 209
            G  G Q     P    P    G     G       P G+GP+GP  +    G R  P  
Sbjct: 392 AGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQ 451

Query: 210 LGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT-----YVGPPGGGGP--------- 255
            G A P    G         P  AN  P     PG        G PG  GP         
Sbjct: 452 DGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGA 511

Query: 256 PGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-------------PGSDGPMGG 302
           PG    P P     +      M  P P G +      G             PG DG  G 
Sbjct: 512 PGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGA 571

Query: 303 MGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            G   P    G  G     G P   P+   G+  PPG P + G+ G
Sbjct: 572 AG---PPGPAGPAGERGEQGAP--GPSGFQGLPGPPGPPGEGGKPG 612



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 82/296 (27%), Positives = 104/296 (35%), Gaps = 73/296 (24%)

Query: 110 GMPGG--PIPPGFFQGPPGSQ--------PSPHAQPPPHNPSSMMGPHSQ--PPG----- 152
           G PGG  PI P   +G PG++          P   P    PS + GP      PG     
Sbjct: 426 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485

Query: 153 GVPGTQPLL--PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-------PGPQNYGSGM 203
           G+PG + L   P    P  + G     G   R  PP   G  G       PGP+    G 
Sbjct: 486 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK----GA 541

Query: 204 RPPPNSLG----PAMPGINMGPG-------AGRPWPNPNSANSIPYSSSSPGTYVG---- 248
              P   G    P  PG+   PG       AG P P   +       +  P  + G    
Sbjct: 542 NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 601

Query: 249 --PPGGGGPPGTPIMPSPADSTNSSDNIYTMINP----------VPPGGSRSNFPMG--- 293
             PPG GG PG   +P  A +         ++ P            PG      P G   
Sbjct: 602 PGPPGEGGKPGDQGVPGEAGAPG-------LVGPRGERGFPGERGSPGAQGLQGPRGLPG 654

Query: 294 -PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            PG+DGP G  G   P    G+ G   + G+P       +GI+ P G   D GE G
Sbjct: 655 TPGTDGPKGASGPAGP---PGAQGPPGLQGMP--GERGAAGIAGPKGDRGDVGEKG 705



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 80/304 (26%), Positives = 96/304 (31%), Gaps = 66/304 (21%)

Query: 102 LGNIPPNDGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHS-------QPPG 152
           L   P  DG  G  GP  P   QGPPG Q      P     + + GP         + P 
Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGPPGLQ----GMPGERGAAGIAGPKGDRGDVGEKGPE 707

Query: 153 GVPG-------TQPLLP----NSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYG 200
           G PG       T P+ P     +     + G P   GS      P   G  GP GP  + 
Sbjct: 708 GAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 767

Query: 201 S--------------------------GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSAN 234
                                      G + P  + GP  P    GP   R    P  A 
Sbjct: 768 GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 827

Query: 235 SIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG- 293
             P ++      VGPPG  G PG P  P P+              P   G      P G 
Sbjct: 828 GFPGAAGR----VGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 883

Query: 294 ------PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGISNPPGTPRDDGE 346
                 PG DGP G  G   P  + G  G   I GLP +       G+  P G P   G 
Sbjct: 884 PGEKGEPGDDGPSGAEGPPGPQGLAGQRG---IVGLPGQRGERGFPGLPGPSGEPGKQGA 940

Query: 347 LGGN 350
            G +
Sbjct: 941 PGAS 944



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 79/284 (27%), Positives = 96/284 (33%), Gaps = 69/284 (24%)

Query: 109  DGMPGGPIPPGFFQGP---PGSQPSPHAQPPP--HNPSSMMGPHSQPPG-GVPGTQ--PL 160
            D  P GP+ P    GP   PG + SP A  PP     + + G   +    G PG    P 
Sbjct: 946  DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPG 1005

Query: 161  LPNSMDPTRQQGHPNMGGSMQRMNP--PRG----MGPMGPG--------PQNYG------ 200
             P    PT +QG     G+   M P  P G     GP GP         P   G      
Sbjct: 1006 SPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRG 1065

Query: 201  ----SGMRPPPNSLGPAMPGINMGPGAGRPWPNP------NSANSIPYSSSSPGTY---- 246
                 G+  PP   G        GP   R  P P      + AN IP     PG      
Sbjct: 1066 FTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSG 1125

Query: 247  ----VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFP-MGPGSDGPMG 301
                 GPPG  GPPG P                    P  PG   S F  +GP   GP  
Sbjct: 1126 ETGPAGPPGNPGPPGPP-------------------GPPGPGIDMSAFAGLGPREKGP-D 1165

Query: 302  GMGGMEPHHMNGSLGSGD--IDGLPKNSPNNISGISNPPGTPRD 343
             +  M      G L   D  +D   K+  N I  I +P G+ ++
Sbjct: 1166 PLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKN 1209



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 73/290 (25%), Positives = 90/290 (31%), Gaps = 48/290 (16%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSM 165
           PP    P G   P   +G  G + +P  +     P +   P    P G PG  P L  + 
Sbjct: 52  PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG-PPGLGGNF 110

Query: 166 DPTRQQGHPNMGGSMQRMNPPRGMGPMG----------PGPQNYGSGMRPP--PNSLGPA 213
                 G     G  Q       MGPMG          PGPQ +      P  P   GP 
Sbjct: 111 AAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM 170

Query: 214 MPGINMGP--------GAGRPW-------PNPNSANSIPYSSSSPGT-----YVGPPGGG 253
            P    GP         AG+P        P P  A   P +   PG      Y G  G  
Sbjct: 171 GPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAK 230

Query: 254 GPPGTPIMPSPADSTNSSDNIYTM-----------INPVPPGGSRSN--FPMGPGSDGPM 300
           G  G P +   + S   + +   M             P    G+R N   P   G  GP+
Sbjct: 231 GEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPV 290

Query: 301 GGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGN 350
           G  GG  P         G+        P    G    PGTP   G  G +
Sbjct: 291 GPAGG--PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS 338



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 54/170 (31%), Positives = 61/170 (35%), Gaps = 17/170 (10%)

Query: 187 RGMGPMG----PGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSS 242
           R  GP G    PG      G + PP   GP  P    GP   R       A         
Sbjct: 29  RQPGPKGQKGEPGDIKDIVGPKGPP---GPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGE 85

Query: 243 PGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNF---PMGP-GSDG 298
           PGT    PG  GPPG P  P P     +             GG++      PMGP G  G
Sbjct: 86  PGT----PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRG 141

Query: 299 PMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
           P G  G   P    G+ G     G+  + P    G   PPG P DDGE G
Sbjct: 142 PPGPAGAPGPQGFQGNPGEPGEPGV--SGPMGPRGPPGPPGKPGDDGEAG 189


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 78.6 bits (192), Expect = 8e-15
 Identities = 79/259 (30%), Positives = 95/259 (36%), Gaps = 28/259 (10%)

Query: 100  PVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGT-- 157
            P L   P N G+ G    PG     PG   +P A+  P  P     P    P G+ G   
Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGL----PGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1140

Query: 158  QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGI 217
             P LP    P    GHP   G       P   G  GP  Q    G     N   P +PG+
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 218  NMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTM 277
            +   G G   P       +P     PG + G PG  GPPG P  P PA            
Sbjct: 1201 SGQKGDG-GLPGIPGNPGLPGPKGEPG-FHGFPGVQGPPGPPGSPGPALEGPKG------ 1252

Query: 278  INPVPPGGSRSNFPMG----PGSDGPMG--GMGGMEPHHMNGSLGSGDIDGLPKNSPNNI 331
             NP P G      P G    PG +GP G  G GG++     G+ G   + GLP      +
Sbjct: 1253 -NPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGE--KGNPGQPGLPGLP-----GL 1304

Query: 332  SGISNPPGTPRDDGELGGN 350
             G   PPG   + G  G N
Sbjct: 1305 KGDQGPPGLQGNPGRPGLN 1323



 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 89/279 (31%), Positives = 111/279 (39%), Gaps = 66/279 (23%)

Query: 102  LGNIPPNDGMPGGPIPPGFF-----QGPPG--SQPSPHAQPPPHNPSSMMGPHSQP--PG 152
            L  IP N G+PG    PGF      QGPPG    P P  + P  NP    GP   P  PG
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP----GPQGPPGRPG 1264

Query: 153  -----GVPGTQ--PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRP 205
                 G+PG +  P LP +     ++G+P   G       P   G  GP P   G+  RP
Sbjct: 1265 PTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLP---GLPGLKGDQGP-PGLQGNPGRP 1320

Query: 206  PPNSL--GPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPS 263
              N +   P +PG+   PG   P   P SA              G PG  GPPG P +P 
Sbjct: 1321 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP-----------EGEPGLIGPPGPPGLPG 1369

Query: 264  PADSTNSSDNIYTMINPVPPG-----GSRS----NFPMG-PGSDGPMG-----------G 302
            P     S  +I    +  PPG     G +       P G PG  GP G           G
Sbjct: 1370 P-----SGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDG 1424

Query: 303  MGGME-PHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 340
             GG +    + G  G+  +DG P   P+ + G   PPGT
Sbjct: 1425 AGGRKGDPGLPGQPGTRGLDGPP--GPDGLQGPPGPPGT 1461



 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 79/254 (31%), Positives = 100/254 (39%), Gaps = 39/254 (15%)

Query: 110 GMPGGPIPPGFFQGPPG--SQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQ--PLLPNSM 165
           G+PG P P    +GPPG   Q      P P  P  + GP   P  G PGT   P +P   
Sbjct: 60  GLPGFPGP----EGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP--GFPGTPGLPGMPGHD 113

Query: 166 DPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRPPPNSL-GPAMPGINMG 220
                QG P   G+      P   G  G    PGP     GM+  P S+   ++PG    
Sbjct: 114 GAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI-PGMKGEPGSIIMSSLPGPKGN 172

Query: 221 PGAGRPWPNPNSANSIPYSSSSPGTY--VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMI 278
           PG    +P P     +P  +  PG     GPPG  GPPG P +P P  +          +
Sbjct: 173 PG----YPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMG--------L 220

Query: 279 NPVPPGGSRSNFPMGPGSDGPMGGMGGM--EPHHMNGSLGSGDIDGLP-KNSPNNISGIS 335
           N   P G +       G  GP G  G +  +   ++     GD  GLP    P    GI 
Sbjct: 221 NFQGPKGEKGE----QGLQGPPGPPGQISEQKRPIDVEFQKGD-QGLPGDRGPPGPPGIR 275

Query: 336 NPPGTP-RDDGELG 348
            PPG P  + GE G
Sbjct: 276 GPPGPPGGEKGEKG 289



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 96/310 (30%), Positives = 115/310 (37%), Gaps = 66/310 (21%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPPG-----FFQGPPGSQPSPHAQPPPHNPSSMMGPH 147
           S  A   P L   P  DG+PG P P G      F+G  G   +P     P N   M  P 
Sbjct: 565 SPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624

Query: 148 SQPPG--------GVPGT--QPLLPNSM-DPTR---QQGHPNMGGSMQRMNPPRGMGPMG 193
             PPG        GV G   QP +P    DP +   Q G P + G     NP R  G +G
Sbjct: 625 FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG-----NPGRD-GDVG 678

Query: 194 -PGPQNYGS--GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP 249
            PG        G+   P S G P +PGI + PG     P P     IP    +PGT  G 
Sbjct: 679 LPGDPGLPGQPGLPGIPGSKGEPGIPGIGL-PGP----PGPKGFPGIPGPPGAPGT-PGR 732

Query: 250 PGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG-----------GSRSNFPMGPGS-- 296
            G  GPPG P  P P               P PPG           G R  FP  PG   
Sbjct: 733 IGLEGPPGPPGFPGP----KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGPPGPPG 787

Query: 297 ----DGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFL 352
               DG  G  G + P+   G +G   + G+       + G   PPG P   G +G   L
Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI------GVQGPPGPPGIP---GPIGQPGL 838

Query: 353 HSFQNDNYSP 362
           H    +   P
Sbjct: 839 HGIPGEKGDP 848



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 85/281 (30%), Positives = 103/281 (36%), Gaps = 45/281 (16%)

Query: 106 PPNDGMPG-----GPI-PPGFFQGPPGSQPSPHAQPPPHNPSS--MMGPHSQP------P 151
           P N G+PG     GP+ PPGF  GPPG       Q    NP    + GP   P      P
Sbjct: 605 PGNPGLPGLPGNIGPMGPPGF--GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQP 662

Query: 152 G--GVPGTQPL-----LPNSMDPTRQQGHPNMGGSMQRMNPPRGMG-PMGPGPQNYGSGM 203
           G  G+PG         LP       Q G P + GS      P G+G P  PGP+ +  G+
Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIP-GIGLPGPPGPKGF-PGI 720

Query: 204 RPPPNSLG-PAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGT--------------YV 247
             PP + G P   G+   PG  G P P      ++P     PG               + 
Sbjct: 721 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 780

Query: 248 GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGME 307
           GPPG  G  G   +P P      +     M  P  PG      P  PG  GP+G  G   
Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG--- 837

Query: 308 PHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            H + G  G     GL    P    G    PG P   G  G
Sbjct: 838 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG 878



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 87/314 (27%), Positives = 102/314 (32%), Gaps = 79/314 (25%)

Query: 103  GNIPPNDGMPGGPIPPGF----FQGPPGSQ--PSPHAQPPPHNPSSMMGPHSQPPGGVPG 156
            G++ PN G PG   PPG      QGPPG    P P  QP  H      G    P   VPG
Sbjct: 799  GDVGPN-GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPG 857

Query: 157  T-----QPLLPNSMDPTRQQGHPNMGGS------------MQRMNPPRGMGPMG------ 193
                   P +P +  P    G P + G             M  M PP   GP+G      
Sbjct: 858  PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917

Query: 194  ----------------PGPQNYGSGMRPP----------PNSLG-------PAMPGINMG 220
                            PGP         P          PN LG       P +PGI   
Sbjct: 918  VPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI--- 974

Query: 221  PGAGRPWPNPNSANSIPYSSSSPGT-----YVGPPGGGGPPGTPIMPSPADSTNSSDNIY 275
            PG       P     +P     PG        GPPG  G PG P  P           I 
Sbjct: 975  PGVS----GPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 276  TMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGI 334
             M  P P G      P G PG  G   G+ G +    +  + S  + GLP   P    G+
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPG-SPGLPGQKGDKGDPGISSIGLPGLP--GPKGEPGL 1087

Query: 335  SNPPGTPRDDGELG 348
               PG P   G +G
Sbjct: 1088 PGYPGNPGIKGSVG 1101



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 88/304 (28%), Positives = 98/304 (32%), Gaps = 73/304 (24%)

Query: 106  PPND-GMPGGPIPPGFFQGPPGSQPSPHAQ-----PPPHNPSSMMGPHSQP-PGGVPGTQ 158
            PP + G PG P  PG   GPPGS   P        P       MMGP   P P G+PG  
Sbjct: 858  PPGERGSPGIPGAPGPI-GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 159  --PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYGS-------------G 202
              P L        Q G P   G       P   GP GP  P   GS             G
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 203  MRPPPNSLG----PAMPGINMGPGAGRPWPNPNSANSIPYSSS----------------- 241
            +  P    G    P  PG++  PG   P P P     +P                     
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGP-PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 242  SPGTYVGPPGGGGPPGTPIMPS-PADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 300
             P    GPPG  G PG P  P  P    +  D          PG S    P  PG  G  
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD----------PGISSIGLPGLPGPKGEP 1085

Query: 301  GGMGGMEPHHMNGSLGSGDIDGLPKN----------------SPNNISGISNPPGTPRDD 344
            G  G      + GS+G   + GLP                   P    GIS PPG P   
Sbjct: 1086 GLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145

Query: 345  GELG 348
            GE G
Sbjct: 1146 GEPG 1149



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 81/295 (27%), Positives = 98/295 (33%), Gaps = 61/295 (20%)

Query: 99  SPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-------- 150
           S ++ ++P   G PG P PPG  QG PG    P    PP  P  +MGP   P        
Sbjct: 160 SIIMSSLPGPKGNPGYPGPPG-IQGLPGPTGIPGPIGPP-GPPGLMGPPGPPGLPGPKGN 217

Query: 151 -------------------PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGP 191
                              P G PG        +D   Q+G   + G      PP   GP
Sbjct: 218 MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 192 MG-PGPQNYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP 249
            G PG +    G +  P   G P   G N  PG             IP     PG Y G 
Sbjct: 278 PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------IPGLPGDPG-YPGE 323

Query: 250 P---------GGGGPPGTP--IMPSPADSTNSSDNIYTMINPVPPGGSRSNFP---MGPG 295
           P         G  GPPG P  ++P P       +     +  +P       FP     PG
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383

Query: 296 SDGPMGG--MGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
             GP G   MG   P    G  G    +G P  S     G+   PG P   G  G
Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG 438



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 82/283 (28%), Positives = 98/283 (34%), Gaps = 47/283 (16%)

Query: 94  AAAAPSPVLGNIPPNDGMPGGPIPPGF-FQGPPG--SQPSPHAQPPPHNPSSMMGPHSQP 150
           AA    P     P   G  G   PPG    GPPG   QP     P P  P+   GPH  P
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA---GPHIPP 446

Query: 151 PGGV--PGTQPLLPNSMDPTRQQGHPNMGGSM-QRMNPPRGMGPMGPGPQNYGSGMRPPP 207
              +  PG  P  P S      QG   + G          G G  GP  Q    G+  PP
Sbjct: 447 SDEICEPGP-PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 208 NSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPAD 266
            SLG P   G     GA      P     IP +  +PG     PG  G PG  I+  P  
Sbjct: 506 GSLGFPGQKGEKGQAGA----TGPKGLPGIPGAPGAPGF----PGSKGEPGD-ILTFPGM 556

Query: 267 STNSSDNIYTMINPVPPGGSRSNFPMGPGSDG------PMGGMGGMEPHHMNGSLGSGDI 320
             +  +    + +P  PG      P  PG DG      P G  GG+      G  G+  +
Sbjct: 557 KGDKGE----LGSPGAPG--LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610

Query: 321 DGLPKN---------------SPNNISGISNPPGTPRDDGELG 348
            GLP N                   I G++  PG P   G  G
Sbjct: 611 PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKG 653



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 59/189 (31%), Positives = 70/189 (37%), Gaps = 30/189 (15%)

Query: 171 QGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRPPPNSLG----PAMPGINMGPG 222
           +GHP + G      PP   G  G    PGP     G+R PP   G    P +PG+    G
Sbjct: 56  EGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPG-PKGIRGPPGLPGFPGTPGLPGMPGHDG 114

Query: 223 AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVP 282
           A  P   P   N        PG+  G PG  GPPG P +P       S   I     P P
Sbjct: 115 APGPQGIPG-CNGTKGERGFPGS-PGFPGLQGPPGPPGIPGMKGEPGS---IIMSSLPGP 169

Query: 283 PGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPR 342
            G         PG  GP G  G   P  + G +G           P  + G   PPG P 
Sbjct: 170 KGN--------PGYPGPPGIQGLPGPTGIPGPIGPP--------GPPGLMGPPGPPGLPG 213

Query: 343 DDGELGGNF 351
             G +G NF
Sbjct: 214 PKGNMGLNF 222



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 79/275 (28%), Positives = 98/275 (35%), Gaps = 57/275 (20%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSM 165
           P   G+ G P PPG  +G  G Q  P  +  P       G + QP  G+PG    LP   
Sbjct: 269 PGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD----GENGQP--GIPG----LPGDP 318

Query: 166 DPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQ---------NYG-------------SGM 203
               + G     G      PP   G + P P          N G              G+
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI 378

Query: 204 RPPPNSLGPAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP 262
           + PP   GP    +   PG  G P       +  P   S PG    PPG  G PG P +P
Sbjct: 379 QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG----PPGLDGQPGAPGLP 434

Query: 263 SPADSTN----SSDNIYTMINPVPPGGSRSNFPMGPGSDGPMG--GMGGMEPHHMNGSLG 316
            P          SD I     P PPG      P  PG  G  G  G+ G +       +G
Sbjct: 435 GPPGPAGPHIPPSDEI---CEPGPPGP-----PGSPGDKGLQGEQGVKGDKGDTCFNCIG 486

Query: 317 SGDIDGLPKNSPNNISGISNPPGT---PRDDGELG 348
           +G I G P   P  + G+  PPG+   P   GE G
Sbjct: 487 TG-ISG-PPGQP-GLPGLPGPPGSLGFPGQKGEKG 518



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/124 (31%), Positives = 44/124 (35%), Gaps = 10/124 (8%)

Query: 248 GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--GSRS-----NFPMGPGSDGPM 300
           G PG  G PG P  P P               P PPG  G R       FP  PG  G  
Sbjct: 51  GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMP 110

Query: 301 GGMGGMEPHHMNGSLGSGDIDGLPKNSPN--NISGISNPPGTPRDDGELGGNFLHSFQND 358
           G  G   P  + G  G+    G P  SP    + G   PPG P   GE G   + S    
Sbjct: 111 GHDGAPGPQGIPGCNGTKGERGFP-GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169

Query: 359 NYSP 362
             +P
Sbjct: 170 KGNP 173


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 78.6 bits (192), Expect = 8e-15
 Identities = 87/272 (31%), Positives = 110/272 (40%), Gaps = 58/272 (21%)

Query: 102  LGNIPPNDGMPGGPIPPGFF-----QGPPG--SQPSPHAQPPPHNPSSMMGPHSQPPGGV 154
            L  IP N G+PG    PGF      QGPPG    P P  + P  NP    GP  +P  G+
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ-GPPGRP--GL 1265

Query: 155  PGTQ--PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL-- 210
            PG +  P LP +     ++G+P   G       P   G  GP P   G+  RP  N +  
Sbjct: 1266 PGPEGPPGLPGNGGIKGEKGNPGQPGLP---GLPGLKGDQGP-PGLQGNPGRPGLNGMKG 1321

Query: 211  GPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNS 270
             P +PG+   PG   P   P SA              G PG  GPPG P +P P     S
Sbjct: 1322 DPGLPGVPGFPGMKGPSGVPGSAGP-----------EGEPGLIGPPGPPGLPGP-----S 1365

Query: 271  SDNIYTMINPVPPG-----GSRS----NFPMG-PGSDGPMG-----------GMGGME-P 308
              +I    +  PPG     G +       P G PG  GP G           G GG +  
Sbjct: 1366 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD 1425

Query: 309  HHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 340
              + G  G+  +DG P   P+ + G   PPGT
Sbjct: 1426 PGLPGQPGTRGLDGPP--GPDGLQGPPGPPGT 1455



 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 78/255 (30%), Positives = 94/255 (36%), Gaps = 26/255 (10%)

Query: 100  PVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGT-- 157
            P L   P N G+ G    PG     PG   +P A+  P  P     P    P G+ G   
Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGL----PGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1140

Query: 158  QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGI 217
             P LP    P    GHP   G       P   G  GP  Q    G     N   P +PG+
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 218  NMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTM 277
            +   G G   P       +P     PG + G PG  GPPG P  P PA            
Sbjct: 1201 SGQKGDG-GLPGIPGNPGLPGPKGEPG-FHGFPGVQGPPGPPGSPGPALEGPKG------ 1252

Query: 278  INPVPPGGSRSNFPMGPGSDGPMG--GMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGIS 335
             NP P G      P  PG +GP G  G GG++     G+ G   + GLP      + G  
Sbjct: 1253 -NPGPQG--PPGRPGLPGPEGPPGLPGNGGIKGE--KGNPGQPGLPGLP-----GLKGDQ 1302

Query: 336  NPPGTPRDDGELGGN 350
             PPG   + G  G N
Sbjct: 1303 GPPGLQGNPGRPGLN 1317



 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 79/254 (31%), Positives = 100/254 (39%), Gaps = 39/254 (15%)

Query: 110 GMPGGPIPPGFFQGPPG--SQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQ--PLLPNSM 165
           G+PG P P    +GPPG   Q      P P  P  + GP   P  G PGT   P +P   
Sbjct: 60  GLPGFPGP----EGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP--GFPGTPGLPGMPGHD 113

Query: 166 DPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRPPPNSL-GPAMPGINMG 220
                QG P   G+      P   G  G    PGP     GM+  P S+   ++PG    
Sbjct: 114 GAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI-PGMKGEPGSIIMSSLPGPKGN 172

Query: 221 PGAGRPWPNPNSANSIPYSSSSPGTY--VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMI 278
           PG    +P P     +P  +  PG     GPPG  GPPG P +P P  +          +
Sbjct: 173 PG----YPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMG--------L 220

Query: 279 NPVPPGGSRSNFPMGPGSDGPMGGMGGM--EPHHMNGSLGSGDIDGLP-KNSPNNISGIS 335
           N   P G +       G  GP G  G +  +   ++     GD  GLP    P    GI 
Sbjct: 221 NFQGPKGEKGE----QGLQGPPGPPGQISEQKRPIDVEFQKGD-QGLPGDRGPPGPPGIR 275

Query: 336 NPPGTP-RDDGELG 348
            PPG P  + GE G
Sbjct: 276 GPPGPPGGEKGEKG 289



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 96/310 (30%), Positives = 115/310 (37%), Gaps = 66/310 (21%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPPG-----FFQGPPGSQPSPHAQPPPHNPSSMMGPH 147
           S  A   P L   P  DG+PG P P G      F+G  G   +P     P N   M  P 
Sbjct: 565 SPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624

Query: 148 SQPPG--------GVPGT--QPLLPNSM-DPTR---QQGHPNMGGSMQRMNPPRGMGPMG 193
             PPG        GV G   QP +P    DP +   Q G P + G     NP R  G +G
Sbjct: 625 FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG-----NPGRD-GDVG 678

Query: 194 -PGPQNYGS--GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP 249
            PG        G+   P S G P +PGI + PG     P P     IP    +PGT  G 
Sbjct: 679 LPGDPGLPGQPGLPGIPGSKGEPGIPGIGL-PGP----PGPKGFPGIPGPPGAPGT-PGR 732

Query: 250 PGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG-----------GSRSNFPMGPGS-- 296
            G  GPPG P  P P               P PPG           G R  FP  PG   
Sbjct: 733 IGLEGPPGPPGFPGP----KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGPPGPPG 787

Query: 297 ----DGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFL 352
               DG  G  G + P+   G +G   + G+       + G   PPG P   G +G   L
Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI------GVQGPPGPPGIP---GPIGQPGL 838

Query: 353 HSFQNDNYSP 362
           H    +   P
Sbjct: 839 HGIPGEKGDP 848



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 85/281 (30%), Positives = 103/281 (36%), Gaps = 45/281 (16%)

Query: 106 PPNDGMPG-----GPI-PPGFFQGPPGSQPSPHAQPPPHNPSS--MMGPHSQP------P 151
           P N G+PG     GP+ PPGF  GPPG       Q    NP    + GP   P      P
Sbjct: 605 PGNPGLPGLPGNIGPMGPPGF--GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQP 662

Query: 152 G--GVPGTQPL-----LPNSMDPTRQQGHPNMGGSMQRMNPPRGMG-PMGPGPQNYGSGM 203
           G  G+PG         LP       Q G P + GS      P G+G P  PGP+ +  G+
Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIP-GIGLPGPPGPKGF-PGI 720

Query: 204 RPPPNSLG-PAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGT--------------YV 247
             PP + G P   G+   PG  G P P      ++P     PG               + 
Sbjct: 721 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 780

Query: 248 GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGME 307
           GPPG  G  G   +P P      +     M  P  PG      P  PG  GP+G  G   
Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG--- 837

Query: 308 PHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            H + G  G     GL    P    G    PG P   G  G
Sbjct: 838 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG 878



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 87/314 (27%), Positives = 102/314 (32%), Gaps = 79/314 (25%)

Query: 103  GNIPPNDGMPGGPIPPGF----FQGPPGSQ--PSPHAQPPPHNPSSMMGPHSQPPGGVPG 156
            G++ PN G PG   PPG      QGPPG    P P  QP  H      G    P   VPG
Sbjct: 799  GDVGPN-GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPG 857

Query: 157  T-----QPLLPNSMDPTRQQGHPNMGGS------------MQRMNPPRGMGPMG------ 193
                   P +P +  P    G P + G             M  M PP   GP+G      
Sbjct: 858  PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917

Query: 194  ----------------PGPQNYGSGMRPP----------PNSLG-------PAMPGINMG 220
                            PGP         P          PN LG       P +PGI   
Sbjct: 918  VPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI--- 974

Query: 221  PGAGRPWPNPNSANSIPYSSSSPGT-----YVGPPGGGGPPGTPIMPSPADSTNSSDNIY 275
            PG       P     +P     PG        GPPG  G PG P  P           I 
Sbjct: 975  PGVS----GPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 276  TMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGI 334
             M  P P G      P G PG  G   G+ G +    +  + S  + GLP   P    G+
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPG-SPGLPGQKGDKGDPGISSIGLPGLP--GPKGEPGL 1087

Query: 335  SNPPGTPRDDGELG 348
               PG P   G +G
Sbjct: 1088 PGYPGNPGIKGSVG 1101



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 88/304 (28%), Positives = 98/304 (32%), Gaps = 73/304 (24%)

Query: 106  PPND-GMPGGPIPPGFFQGPPGSQPSPHAQ-----PPPHNPSSMMGPHSQP-PGGVPGTQ 158
            PP + G PG P  PG   GPPGS   P        P       MMGP   P P G+PG  
Sbjct: 858  PPGERGSPGIPGAPGPI-GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 159  --PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYGS-------------G 202
              P L        Q G P   G       P   GP GP  P   GS             G
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 203  MRPPPNSLG----PAMPGINMGPGAGRPWPNPNSANSIPYSSS----------------- 241
            +  P    G    P  PG++  PG   P P P     +P                     
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGP-PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 242  SPGTYVGPPGGGGPPGTPIMPS-PADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 300
             P    GPPG  G PG P  P  P    +  D          PG S    P  PG  G  
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD----------PGISSIGLPGLPGPKGEP 1085

Query: 301  GGMGGMEPHHMNGSLGSGDIDGLPKN----------------SPNNISGISNPPGTPRDD 344
            G  G      + GS+G   + GLP                   P    GIS PPG P   
Sbjct: 1086 GLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145

Query: 345  GELG 348
            GE G
Sbjct: 1146 GEPG 1149



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 81/295 (27%), Positives = 98/295 (33%), Gaps = 61/295 (20%)

Query: 99  SPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-------- 150
           S ++ ++P   G PG P PPG  QG PG    P    PP  P  +MGP   P        
Sbjct: 160 SIIMSSLPGPKGNPGYPGPPG-IQGLPGPTGIPGPIGPP-GPPGLMGPPGPPGLPGPKGN 217

Query: 151 -------------------PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGP 191
                              P G PG        +D   Q+G   + G      PP   GP
Sbjct: 218 MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 192 MG-PGPQNYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP 249
            G PG +    G +  P   G P   G N  PG             IP     PG Y G 
Sbjct: 278 PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------IPGLPGDPG-YPGE 323

Query: 250 P---------GGGGPPGTP--IMPSPADSTNSSDNIYTMINPVPPGGSRSNFP---MGPG 295
           P         G  GPPG P  ++P P       +     +  +P       FP     PG
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383

Query: 296 SDGPMGG--MGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
             GP G   MG   P    G  G    +G P  S     G+   PG P   G  G
Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG 438



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 82/283 (28%), Positives = 98/283 (34%), Gaps = 47/283 (16%)

Query: 94  AAAAPSPVLGNIPPNDGMPGGPIPPGF-FQGPPG--SQPSPHAQPPPHNPSSMMGPHSQP 150
           AA    P     P   G  G   PPG    GPPG   QP     P P  P+   GPH  P
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA---GPHIPP 446

Query: 151 PGGV--PGTQPLLPNSMDPTRQQGHPNMGGSM-QRMNPPRGMGPMGPGPQNYGSGMRPPP 207
              +  PG  P  P S      QG   + G          G G  GP  Q    G+  PP
Sbjct: 447 SDEICEPGP-PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 208 NSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPAD 266
            SLG P   G     GA      P     IP +  +PG     PG  G PG  I+  P  
Sbjct: 506 GSLGFPGQKGEKGQAGA----TGPKGLPGIPGAPGAPGF----PGSKGEPGD-ILTFPGM 556

Query: 267 STNSSDNIYTMINPVPPGGSRSNFPMGPGSDG------PMGGMGGMEPHHMNGSLGSGDI 320
             +  +    + +P  PG      P  PG DG      P G  GG+      G  G+  +
Sbjct: 557 KGDKGE----LGSPGAPG--LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610

Query: 321 DGLPKN---------------SPNNISGISNPPGTPRDDGELG 348
            GLP N                   I G++  PG P   G  G
Sbjct: 611 PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKG 653



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 59/189 (31%), Positives = 70/189 (37%), Gaps = 30/189 (15%)

Query: 171 QGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRPPPNSLG----PAMPGINMGPG 222
           +GHP + G      PP   G  G    PGP     G+R PP   G    P +PG+    G
Sbjct: 56  EGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPG-PKGIRGPPGLPGFPGTPGLPGMPGHDG 114

Query: 223 AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVP 282
           A  P   P   N        PG+  G PG  GPPG P +P       S   I     P P
Sbjct: 115 APGPQGIPG-CNGTKGERGFPGS-PGFPGLQGPPGPPGIPGMKGEPGS---IIMSSLPGP 169

Query: 283 PGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPR 342
            G         PG  GP G  G   P  + G +G           P  + G   PPG P 
Sbjct: 170 KGN--------PGYPGPPGIQGLPGPTGIPGPIGPP--------GPPGLMGPPGPPGLPG 213

Query: 343 DDGELGGNF 351
             G +G NF
Sbjct: 214 PKGNMGLNF 222



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 79/275 (28%), Positives = 98/275 (35%), Gaps = 57/275 (20%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSM 165
           P   G+ G P PPG  +G  G Q  P  +  P       G + QP  G+PG    LP   
Sbjct: 269 PGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD----GENGQP--GIPG----LPGDP 318

Query: 166 DPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQ---------NYG-------------SGM 203
               + G     G      PP   G + P P          N G              G+
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI 378

Query: 204 RPPPNSLGPAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP 262
           + PP   GP    +   PG  G P       +  P   S PG    PPG  G PG P +P
Sbjct: 379 QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG----PPGLDGQPGAPGLP 434

Query: 263 SPADSTN----SSDNIYTMINPVPPGGSRSNFPMGPGSDGPMG--GMGGMEPHHMNGSLG 316
            P          SD I     P PPG      P  PG  G  G  G+ G +       +G
Sbjct: 435 GPPGPAGPHIPPSDEI---CEPGPPGP-----PGSPGDKGLQGEQGVKGDKGDTCFNCIG 486

Query: 317 SGDIDGLPKNSPNNISGISNPPGT---PRDDGELG 348
           +G I G P   P  + G+  PPG+   P   GE G
Sbjct: 487 TG-ISG-PPGQP-GLPGLPGPPGSLGFPGQKGEKG 518



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/124 (31%), Positives = 44/124 (35%), Gaps = 10/124 (8%)

Query: 248 GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--GSRS-----NFPMGPGSDGPM 300
           G PG  G PG P  P P               P PPG  G R       FP  PG  G  
Sbjct: 51  GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMP 110

Query: 301 GGMGGMEPHHMNGSLGSGDIDGLPKNSPN--NISGISNPPGTPRDDGELGGNFLHSFQND 358
           G  G   P  + G  G+    G P  SP    + G   PPG P   GE G   + S    
Sbjct: 111 GHDGAPGPQGIPGCNGTKGERGFP-GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169

Query: 359 NYSP 362
             +P
Sbjct: 170 KGNP 173


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 87/291 (29%), Positives = 107/291 (36%), Gaps = 61/291 (20%)

Query: 110 GMPGGPIPPGFFQGPPG--------SQPSPHAQPPPHNPSSMMGPHSQP-PGGVPGTQPL 160
           G+PG P PP    GPPG         +  P   P P  P    G   +P   G+PG   +
Sbjct: 29  GLPGPPGPP----GPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGV 84

Query: 161 --LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNY--------GSGMRPPPNS 209
             L     P   +G P   GS+    PP G+G  G PGP           G G+R PP  
Sbjct: 85  DGLTGRDGPPGPKGAPGERGSLGPPGPP-GLGGKGLPGPPGEAGVSGPPGGIGLRGPPGP 143

Query: 210 LG-PAMPGINMGPG-AGRPWPNPNSANSIPYSSSSPGTYVGPP----------------- 250
            G P +PG    PG  G P   P  A  +   S  P    GPP                 
Sbjct: 144 SGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGE 203

Query: 251 -GGGGPPGTPIMPSPADSTNS-----SDNIYTMINPVPPGGSRSNFPMG-------PGSD 297
            G  G  G P  P PA    S        +  +  P+ P G R   P+G       PG+ 
Sbjct: 204 VGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRG--PIGFRGPPGIPGAP 261

Query: 298 GPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
           G  G  G   P    G  G     G PK +P  ++G S  PG P  DG+ G
Sbjct: 262 GKAGDRGERGPEGFRGPKGDLGRPG-PKGTP-GVAGPSGEPGMPGKDGQNG 310



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 75/279 (26%), Positives = 92/279 (32%), Gaps = 58/279 (20%)

Query: 110 GMPGGPIPPGFFQGPPGSQPSPHAQPPP--------HNPSSMMGPHSQP----PGGVPGT 157
           G PG P   GF QG  GS   P    P           P    GP          G+PG 
Sbjct: 394 GPPGAPGVRGF-QGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGD 452

Query: 158 QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLG----PA 213
           +      + P+   G     GS   + P    G  GP   +   G+  PP  LG    P 
Sbjct: 453 K----GELGPSGLVGPKGESGSRGELGPK---GTQGPNGTSGVQGVPGPPGPLGLQGVPG 505

Query: 214 MPGINMGPGAGRPWPNPNSANSI---------------------PYSSSSPGTYVGPPGG 252
           +PGI   PG      +      +                     P S   PG   GPPG 
Sbjct: 506 VPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGP-AGPPGP 564

Query: 253 GGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--GSRSNF-PMGPGSDGPMGGMGGMEPH 309
            GPPG+   P              + +P P G  G R +    G G DGP G  G   P 
Sbjct: 565 PGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQ 624

Query: 310 HMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            + G+   G  DG P        G   PPG P   G +G
Sbjct: 625 GVPGTSKDGQ-DGAP--------GEPGPPGDPGLPGAIG 654



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 84/327 (25%), Positives = 101/327 (30%), Gaps = 94/327 (28%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSM 165
           P   G+PG P PPG    PPG  P  H    P   + +  P   PPG  P   P +P   
Sbjct: 141 PGPSGLPGLPGPPG----PPG--PPGHPGVLPEGATDLQCPSICPPG--PPGPPGMPGFK 192

Query: 166 DPTRQQGHPN-MGGSMQRMNP----------------PRGM----GPMGPGPQNYGSGMR 204
            PT  +G    +G   ++ +P                PRG+    GP+GP       G R
Sbjct: 193 GPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFR 252

Query: 205 PPPNSLGP----------------------AMPGINMGPGAGRP-----WPNPNSANSIP 237
            PP   G                         PG    PG   P      P  +  N +P
Sbjct: 253 GPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVP 312

Query: 238 YSSSSPGTYV--GPPGGGGPPGTPIMPSPADSTNSS---------DNIYTMINPVPPG-- 284
                 G     G PG  GP G P +P  A S                     P  PG  
Sbjct: 313 GLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDA 372

Query: 285 ---GSRSNF----------PMGP----------GSDGPMGGMGGMEPHHMNGSLGSGDID 321
              G R             P GP          G  G MG  G   P  + G +G     
Sbjct: 373 GMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPG 432

Query: 322 GLPKNSPNNISGISNPPGTPRDDGELG 348
           G     P    GI+   G P D GELG
Sbjct: 433 GAA--GPKGDQGIAGSDGLPGDKGELG 457



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 70/253 (27%), Positives = 87/253 (34%), Gaps = 45/253 (17%)

Query: 100 PVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQP 159
           P    +P   G PG P PPG            H    P   + +  P   PPG  P   P
Sbjct: 141 PGPSGLPGLPGPPGPPGPPG------------HPGVLPEGATDLQCPSICPPG--PPGPP 186

Query: 160 LLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNYGS--GMRPPPNSLGPAMPG 216
            +P    PT  +G     G       P   GP G PG        G+R  P  LGP  PG
Sbjct: 187 GMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGP--PG 244

Query: 217 INMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYT 276
            + GP   R    P      P  +   G   GP G  GP G    P P  +         
Sbjct: 245 -DRGPIGFR---GPPGIPGAPGKAGDRGER-GPEGFRGPKGDLGRPGPKGT--------- 290

Query: 277 MINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGIS 335
                P     S  P  PG DG  G  G      ++G  G    +G P +  PN + G+ 
Sbjct: 291 -----PGVAGPSGEPGMPGKDGQNGVPG------LDGQKGEAGRNGAPGEKGPNGLPGLP 339

Query: 336 NPPGTPRDDGELG 348
              G+  + GE G
Sbjct: 340 GRAGSKGEKGERG 352



 Score = 36.2 bits (82), Expect = 0.048
 Identities = 37/129 (28%), Positives = 43/129 (33%), Gaps = 19/129 (14%)

Query: 211 GPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNS 270
           G    G+   PG   P P     + I   +  PG   GPPG  G PG P  P  A     
Sbjct: 24  GAQRVGLPGPPGPPGP-PGKPGQDGIDGEAGPPGL-PGPPGPKGAPGKPGKPGEAGL--- 78

Query: 271 SDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNN 330
                    P  PG          G DGP G  G        G  G   + G     P  
Sbjct: 79  ---------PGLPGVDGLT-----GRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPG 124

Query: 331 ISGISNPPG 339
            +G+S PPG
Sbjct: 125 EAGVSGPPG 133


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 91/310 (29%), Positives = 110/310 (35%), Gaps = 53/310 (17%)

Query: 94  AAAAPSP-----VLGNIPPNDGMPGGPIPPGFFQGPPG-----------------SQPSP 131
           AA  P P     V G++ P  G  G P P    QGPPG                     P
Sbjct: 648 AAGEPGPHGPPGVPGSVGPK-GSSGSPGP----QGPPGPVGLQGLRGEVGLPGVKGDKGP 702

Query: 132 HAQPPPHNPSSMMGPH--SQPPG--GVPGT--QPLLPNSMDPTRQQGHPNMGGSMQRMNP 185
              P P       GP   +  PG  G+PG   +P    +M P    GH    G       
Sbjct: 703 MGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGM 762

Query: 186 PRGMGPMGPGPQNYGSGMRPPPNSLG----PAMPGINMGPGA-GRPWPNPNSAN-SIPYS 239
           P   GP GP       G+  P    G    P  PGI   PGA G+   +  S+  ++P  
Sbjct: 763 PGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGP 822

Query: 240 SSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGP 299
              PG  +GPPG   PPG P    PA      + +     P PPG      P  PG  GP
Sbjct: 823 PGPPGA-MGPPG---PPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGP 878

Query: 300 MG--GMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQN 357
            G  G G   P    GS  S        NS   +SG   PPG P   G+ G       Q 
Sbjct: 879 RGPPGEGLPGPPGPPGSFLS--------NSETFLSGPPGPPGPPGPKGDQGPPGPRGHQG 930

Query: 358 DNYSPSMTMS 367
           +   P  + S
Sbjct: 931 EQGLPGFSTS 940



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 71/250 (28%), Positives = 90/250 (36%), Gaps = 38/250 (15%)

Query: 111  MPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQ-PLLPNSMDPTR 169
            +PG P PPG   GPPG   +P    P   P      + Q P G PG + P  P+   P  
Sbjct: 819  VPGPPGPPGAM-GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPG 877

Query: 170  QQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPN 229
             +G P  G       PP   GP G    N  + +  PP   GP  P  + GP   R    
Sbjct: 878  PRGPPGEG----LPGPP---GPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQG 930

Query: 230  PNSANSIPYSSSSPG--TYVGPPGGGGP------------PGTPIMPSPADSTNSSDNIY 275
                     S SS       GPPG  GP            PG   +PS      SS  +Y
Sbjct: 931  EQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMY 990

Query: 276  TMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGIS 335
                P PPG         PG  G +   G     +++  + S  I        + +SG+ 
Sbjct: 991  VSGPPGPPG--------PPGPPGSISSSGQEIQQYISEYMQSDSI-------RSYLSGVQ 1035

Query: 336  NPPGTPRDDG 345
             PPG P   G
Sbjct: 1036 GPPGPPGPPG 1045



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 65/240 (27%), Positives = 79/240 (32%), Gaps = 39/240 (16%)

Query: 128 QPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPR 187
           Q + + +  P     M  P  +   G PGT P +P  +     QG     GS+     P 
Sbjct: 560 QENGNLRGSPGPKGDMGSPGPKGDRGFPGT-PGIPGPLGHPGPQGPKGQKGSV---GDPG 615

Query: 188 GMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYV 247
             GPMG   Q    G   P    GP   G     GA    P P+    +P S       V
Sbjct: 616 MEGPMG---QRGREGPMGPRGEAGPPGSGEKGERGAAGE-PGPHGPPGVPGS-------V 664

Query: 248 GPPGGGGPPGTPIMPSPADSTNSSDNI---------YTMINPVPPGGSRSNFPMG----- 293
           GP G  G PG    P P         +           M  P P G      P G     
Sbjct: 665 GPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEP 724

Query: 294 -----PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
                PG+ G  G  G M P   +G  G     GL       + GI  PPG   D G+ G
Sbjct: 725 GMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGL-----TGMPGIRGPPGPSGDPGKPG 779



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 31/104 (29%), Positives = 38/104 (36%), Gaps = 13/104 (12%)

Query: 248 GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGM 306
           GP G  G PGTP +P P            + +P P G       +G PG +GPMG  G  
Sbjct: 579 GPKGDRGFPGTPGIPGP------------LGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626

Query: 307 EPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGN 350
            P    G  G        +       G   PPG P   G  G +
Sbjct: 627 GPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSS 670



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 53/209 (25%), Positives = 74/209 (35%), Gaps = 31/209 (14%)

Query: 143  MMGPHSQP-PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNY-- 199
            +MGP   P P G  G   LL         +    M  S   +  P   GP G    +Y  
Sbjct: 1104 LMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE 1163

Query: 200  ------GS---GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYV--- 247
                  GS   G+  PP   GP  PGI      G  W + +  +   Y  ++  +++   
Sbjct: 1164 LLSLLRGSEFRGIVGPPGPPGP--PGI-----PGNVWSSISVEDLSSYLHTAGLSFIPGP 1216

Query: 248  ----GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGM 303
                GPPG  GPPG     +   + NS      +I+ +     RS     PG  GP G  
Sbjct: 1217 PGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPP 1276

Query: 304  G-----GMEPHHMNGSLGSGDIDGLPKNS 327
            G       +  H  GS  S     + + S
Sbjct: 1277 GDSRLLSTDASHSRGSSSSSHSSSVRRGS 1305



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 48/189 (25%), Positives = 68/189 (35%), Gaps = 33/189 (17%)

Query: 189  MGPMGP----GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSS---- 240
            MGP GP    G    GS +      L   +       G     P P     +P +S    
Sbjct: 1105 MGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEEL 1164

Query: 241  ------SSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP 294
                  S     VGPPG  GPPG   +P    S+ S +++ + ++        +     P
Sbjct: 1165 LSLLRGSEFRGIVGPPGPPGPPG---IPGNVWSSISVEDLSSYLHT-------AGLSFIP 1214

Query: 295  GSDGPMGGMGGMEPHHMNGSLGSGDIDGLPK---------NSPNNISGISNPPGTPRDDG 345
            G  GP G  G   P  ++G+L +   +              SP+  S I  PPG P   G
Sbjct: 1215 GPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQG 1274

Query: 346  ELGGNFLHS 354
              G + L S
Sbjct: 1275 PPGDSRLLS 1283



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 56/204 (27%), Positives = 81/204 (39%), Gaps = 33/204 (16%)

Query: 110  GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-PGGVPGTQPLLPNSMDPT 168
            G+PG P PPG    P  S     +         ++GP   P P G+PG    + +S+   
Sbjct: 1146 GLPGPPGPPGL---PGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGN---VWSSISVE 1199

Query: 169  RQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWP 228
                + +  G      PP   GP  PGP+             GP  PG++ G  A     
Sbjct: 1200 DLSSYLHTAGLSFIPGPPGPPGP--PGPR-------------GP--PGVS-GALATYAAE 1241

Query: 229  NPNSANS--IPY-SSSSPGTYV----GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPV 281
            N +S  S  I Y +S    +++    GPPG  GPPG   + S   S +   +  +  + V
Sbjct: 1242 NSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV 1301

Query: 282  PPGGS-RSNFPMGPGSDGPMGGMG 304
              G S  S+   G G  G +G  G
Sbjct: 1302 RRGSSYSSSMSTGGGGAGSLGAGG 1325



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 64/245 (26%), Positives = 88/245 (35%), Gaps = 51/245 (20%)

Query: 106  PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSM 165
            PP    P GP       G PG+   P    P    SS     S PPG  P   P  P S+
Sbjct: 952  PPGPPGPQGPKGDKGDPGVPGALGIPSG--PSEGGSSSTMYVSGPPG--PPGPPGPPGSI 1007

Query: 166  DPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGR 225
              + Q+    +   MQ               ++Y SG++ PP   GP  P   +      
Sbjct: 1008 SSSGQEIQQYISEYMQ-----------SDSIRSYLSGVQGPPGPPGPPGPVTTI------ 1050

Query: 226  PWPNPNSANSIPYS--SSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPP 283
                  +  +  YS  +S   +Y+   G G         S   S+ SS++I  ++     
Sbjct: 1051 ------TGETFDYSELASHVVSYLRTSGYG--------VSLFSSSISSEDILAVLQRDDV 1096

Query: 284  GGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKN-----SPNNIS-GISN 336
                  + MGP G  GP G  G       +GSL S D   L        S + IS G+  
Sbjct: 1097 RQYLRQYLMGPRGPPGPPGASG-------DGSLLSLDYAELSSRILSYMSSSGISIGLPG 1149

Query: 337  PPGTP 341
            PPG P
Sbjct: 1150 PPGPP 1154


>gi|23510333 pygopus homolog 2 [Homo sapiens]
          Length = 406

 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 86/293 (29%), Positives = 109/293 (37%), Gaps = 55/293 (18%)

Query: 73  APERRDTCEHSSEAKAFHDYSAA-----AAPSPVLGNIPPNDGMP-----GGPIPPGFFQ 122
           AP      +H   +  F D   A     AAP P LG+  P  G        G +PPG+  
Sbjct: 62  APPPTPMVDHLVASNPFEDDFGAPKVGVAAP-PFLGSPVPFGGFRVQGGMAGQVPPGYST 120

Query: 123 GPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQR 182
           G  G       QPPP  P+ M    + PP G PG  P  P +M+   Q  +  +G   Q 
Sbjct: 121 GGGGGPQPLRRQPPPFPPNPMGPAFNMPPQG-PGYPP--PGNMNFPSQPFNQPLG---QN 174

Query: 183 MNPPRGM---GPMGP-GPQNYGSGMRPPPNSLGP-------AMPGINMGPGAGRPWPNPN 231
            +PP G    GP+G  GP    +  +PP   LGP       A PG   GP   +  P   
Sbjct: 175 FSPPSGQMMPGPVGGFGPMISPTMGQPPRAELGPPSLSQRFAQPGAPFGPSPLQR-PGQG 233

Query: 232 SANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFP 291
             +  P +S  PG   G PG GG  G   +  PA +                      FP
Sbjct: 234 LPSLPPNTSPFPGPDPGFPGPGGEDGGKPLNPPASTA---------------------FP 272

Query: 292 MGPGSDGPMGGMGGMEPHHMNGSLGSG----DIDGL-PKNSPNNISGISNPPG 339
             P S  P   + G +P     S G G    D + L P       SG   PPG
Sbjct: 273 QEPHSGSPAAAVNGNQPSFPPNSSGRGGGTPDANSLAPPGKAGGGSGPQPPPG 325



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 66/243 (27%), Positives = 83/243 (34%), Gaps = 40/243 (16%)

Query: 122 QGPPGSQPSPHAQPPPHNPSSMMGPHS-QPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSM 180
           QGP  S  +  A PP      ++  +  +   G P      P  +      G   + G M
Sbjct: 51  QGPAYSHLTEFAPPPTPMVDHLVASNPFEDDFGAPKVGVAAPPFLGSPVPFGGFRVQGGM 110

Query: 181 QRMNPPRGMGPMGPGPQNYGSGMRP-PPNSLGPAMPGINMGP-GAGRPWPNPNSANSIPY 238
               PP      G GPQ       P PPN +GPA    NM P G G P P   +  S P+
Sbjct: 111 AGQVPPGYSTGGGGGPQPLRRQPPPFPPNPMGPAF---NMPPQGPGYPPPGNMNFPSQPF 167

Query: 239 SS------SSPGTYV--GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNF 290
           +       S P   +  GP GG GP  +P M  P  +          + P P    R   
Sbjct: 168 NQPLGQNFSPPSGQMMPGPVGGFGPMISPTMGQPPRAE---------LGP-PSLSQRFAQ 217

Query: 291 PMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGN 350
           P  P    P+   G                 GLP   PN        PG P   GE GG 
Sbjct: 218 PGAPFGPSPLQRPG----------------QGLPSLPPNTSPFPGPDPGFPGPGGEDGGK 261

Query: 351 FLH 353
            L+
Sbjct: 262 PLN 264



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 41/136 (30%), Positives = 52/136 (38%), Gaps = 23/136 (16%)

Query: 84  SEAKAFHDYSAAAAPSPV------LGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPP 137
           S ++ F    A   PSP+      L ++PPN     GP  PGF    PG +       PP
Sbjct: 210 SLSQRFAQPGAPFGPSPLQRPGQGLPSLPPNTSPFPGP-DPGF--PGPGGEDGGKPLNPP 266

Query: 138 HNPSSMMGPHS-QPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGP 196
            + +    PHS  P   V G QP  P           PN  G          + P  PG 
Sbjct: 267 ASTAFPQEPHSGSPAAAVNGNQPSFP-----------PNSSGRGGGTPDANSLAP--PGK 313

Query: 197 QNYGSGMRPPPNSLGP 212
              GSG +PPP  + P
Sbjct: 314 AGGGSGPQPPPGLVYP 329


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 80/262 (30%), Positives = 101/262 (38%), Gaps = 44/262 (16%)

Query: 112 PGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDP---T 168
           P GP+      G  G+  +P A+ P  +P +   P S  P G PG Q     S  P    
Sbjct: 409 PPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQ----GSTGPQGIR 464

Query: 169 RQQGHPNMGGSMQRMNP-----PRGM-GPMGPGPQNYGSGMRPPPNSLGP-------AMP 215
            Q G P + G      P     P G+ GP+GP  +    G R  P ++GP         P
Sbjct: 465 GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAP 524

Query: 216 GINMGPGA-GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNI 274
           G    PG+ G P P        P  SS P    G  G  G PG P +P     T      
Sbjct: 525 GNRGFPGSDGLPGPKGAQGERGPVGSSGP---KGSQGDPGRPGEPGLPGARGLTG----- 576

Query: 275 YTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLG-------SGDIDGLPKN 326
               NP   G      P+G PG DG  G  G +      GS+G       SGD  G P  
Sbjct: 577 ----NPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGD-PGKPGE 631

Query: 327 SPNNISGISNPPGTPRDDGELG 348
           + N  +G+    G P  DGE+G
Sbjct: 632 AGN--AGVPGQRGAPGKDGEVG 651



 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 77/269 (28%), Positives = 93/269 (34%), Gaps = 32/269 (11%)

Query: 100 PVLGNIPPNDGMPG-----GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGV 154
           P  G  P + G+PG     GP+ P   +G PG +  P     P       G     P G 
Sbjct: 686 PGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGS 745

Query: 155 PGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPP---RGMGPMGPGPQNYGSGMRPPPNSLG 211
           PG     P    P   QG P   G      P     G+G  G        G R  P  LG
Sbjct: 746 PGPSG-TPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLG 804

Query: 212 PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT-----------YVGPPGGGGPPGTPI 260
           P  P    GP   +  P P      P S  +PG+           + GP G  G PG  +
Sbjct: 805 PPGPA---GPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPG--V 859

Query: 261 MPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSGD 319
              P +     D      +P P G + S  P GP G  G  GG G   P    G  GS  
Sbjct: 860 KGEPGEPGQKGD----AGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAG 915

Query: 320 IDGLPKNSPNNISGISNPPGTPRDDGELG 348
             G P   P    G + P G P  +G  G
Sbjct: 916 RVGPP--GPAGAPGPAGPLGEPGKEGPPG 942



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 78/278 (28%), Positives = 97/278 (34%), Gaps = 55/278 (19%)

Query: 110 GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTR 169
           G PG   PPG  QGP G +  P  +P P  P  + G   +P  GVPG     P +  P  
Sbjct: 129 GRPGPAGPPGS-QGPRGER-GPKGRPGPRGPQGIDG---EP--GVPGQ----PGAPGPPG 177

Query: 170 QQGHPNMGGSMQRMNP------------------PRGMGPMGP-GPQNY-----GSGMRP 205
              HP   G  +  +                   P  +GP+GP GPQ       G+G   
Sbjct: 178 HPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTG 237

Query: 206 PPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT--YVGPPGGGGPPGTPIMPS 263
           PP   G   P   +G       P     +  P  + +PG   + G PG  G PG P +P 
Sbjct: 238 PPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPG 297

Query: 264 PADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGL 323
                     +      V   GS+       G  GPMG MG + P  M G  G     G 
Sbjct: 298 -LKGHRGHKGLEGPKGEVGAPGSKGE----AGPTGPMGAMGPLGPRGMPGERGRLGPQGA 352

Query: 324 PKN-------------SPNNISGISNPPGTPRDDGELG 348
           P                P  I G S  PG P   GE G
Sbjct: 353 PGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 78/283 (27%), Positives = 102/283 (36%), Gaps = 45/283 (15%)

Query: 106  PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLL---- 161
            P   G PG   PPG  QG PG +       P  +   +    ++   G  G + L     
Sbjct: 746  PGPSGTPGDTGPPGL-QGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLG 804

Query: 162  -PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGP-AMPGINM 219
             P    PT ++G P   G +    PP   G  G   +N  +G        GP   PG+  
Sbjct: 805  PPGPAGPTGEKGEPGPRGLV---GPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKG 861

Query: 220  GPG-------AGRPWPN-------PNSANSIPYSSSSPGTYVGPPGGGGPPGTPIM---P 262
             PG       AG P P        P+  N +P      GT  GPPG  G PG+      P
Sbjct: 862  EPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQ-GPPGATGFPGSAGRVGPP 920

Query: 263  SPADSTNSSDNIYTMINPVPPG-----GSRSNF--------PMGPGSDGPMG--GMGGME 307
             PA +   +  +       PPG     GS            P GPG  G  G  G  G +
Sbjct: 921  GPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPD 980

Query: 308  -PHHMNGSLGSGDIDGLP-KNSPNNISGISNPPGTPRDDGELG 348
             P    G+ G   I G+P +     + G+  P GTP   G  G
Sbjct: 981  GPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG 1023



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 75/270 (27%), Positives = 89/270 (32%), Gaps = 41/270 (15%)

Query: 95   AAAPSPV--LGNIPPNDGMPGGPIPPGFF--------QGPPGS-----QPSPHAQPPPHN 139
            A AP P   LG  P  +G PG    PG           GPPG       P    QP P  
Sbjct: 923  AGAPGPAGPLGE-PGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDG 981

Query: 140  PSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNY 199
            P    G   Q   G+ G    +P         G P   G+  ++ P    G  GP     
Sbjct: 982  PPGPAGTTGQR--GIVG----MPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGP----- 1030

Query: 200  GSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTP 259
              G   PP S GP       GP      P  + A         PG   G PG  G PGTP
Sbjct: 1031 -PGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGP-AGLPGSQGAPGTP 1088

Query: 260  -IMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSG 318
              + +P D+    D       P+ P G      + PG  GP G  G        G  G  
Sbjct: 1089 GPVGAPGDAGQRGDP--GSRGPIGPPGRAGKRGL-PGPQGPRGDKGDHGDRGDRGQKGHR 1145

Query: 319  DIDGLPKNSPNNISGISNPPGTPRDDGELG 348
               GL         G+  PPG   + G  G
Sbjct: 1146 GFTGL--------QGLPGPPGPNGEQGSAG 1167



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 86/308 (27%), Positives = 101/308 (32%), Gaps = 72/308 (23%)

Query: 102 LGNIPPNDGMPGGPIPPGFFQGP-----PGSQPSPHAQPPPHNPSSMMGPHSQP--PG-- 152
           +G +P + G P GP  P   QG      P   P     P P  P    GP   P  PG  
Sbjct: 208 VGLMPGSVG-PVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGED 266

Query: 153 ---------------GVPGTQ-----PLLPNSM---------DPTRQQGHPNMGGSMQRM 183
                          G PG +     P LP             P  + G P   G     
Sbjct: 267 GEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPT 326

Query: 184 NPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSP 243
            P   MGP+GP       G   P  +  P   G +  PG     P P     IP SS  P
Sbjct: 327 GPMGAMGPLGPRGMPGERGRLGPQGA--PGQRGAHGMPGK----PGPMGPLGIPGSSGFP 380

Query: 244 GT-----YVGPPGGGGPPGTPIM------PSPADSTNSSDNIYTMINP---VPPGGSRSN 289
           G        GP G  GP G          P P  S      I T   P    P G   ++
Sbjct: 381 GNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTS 440

Query: 290 FPMG----PGSDGPMGGMGGMEPHHMNGSLGSGDIDGL-----PKNSPNNISGISNPPGT 340
            P G    PGS GP G  G   P  + G  G   + G      PK  P    GI  P G 
Sbjct: 441 GPPGSAGPPGSPGPQGSTG---PQGIRGQPGDPGVPGFKGEAGPKGEPGP-HGIQGPIGP 496

Query: 341 PRDDGELG 348
           P ++G+ G
Sbjct: 497 PGEEGKRG 504



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 75/266 (28%), Positives = 93/266 (34%), Gaps = 50/266 (18%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQ----PLL 161
           P +DG+PG     G  +GP GS     +Q  P  P     P ++   G PG Q     L 
Sbjct: 530 PGSDGLPGPKGAQGE-RGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLG 588

Query: 162 PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPG--------PQNYGS----GMRPPPNS 209
           P  +    + G P   GS+     P  MG  GP         P   G+    G R  P  
Sbjct: 589 P--LGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGK 646

Query: 210 LGPAMPGINMGP-------GAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP 262
            G   P   +GP       G   P P P     +P          GPPG GG PG   +P
Sbjct: 647 DGEVGPSGPVGPPGLAGERGEQGP-PGPTGFQGLPGPP-------GPPGEGGKPGDQGVP 698

Query: 263 SPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDG 322
               +          + P+ P G R N    PG  G  G  G      M G  G     G
Sbjct: 699 GDPGA----------VGPLGPRGERGN----PGERGEPGITGLPGEKGMAGGHGPDGPKG 744

Query: 323 LPKNSPNNISGISNPPGTPRDDGELG 348
            P   P+   G + PPG     GE G
Sbjct: 745 SP--GPSGTPGDTGPPGLQGMPGERG 768



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 52/183 (28%), Positives = 63/183 (34%), Gaps = 17/183 (9%)

Query: 172 GHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPN 231
           G+ N G   +      G+ P+  G +    G   PP S GP       G    +  P P 
Sbjct: 103 GNTNFGRGRKGQKGEPGLVPVVTGIRGR-PGPAGPPGSQGPR------GERGPKGRPGPR 155

Query: 232 SANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFP 291
               I      PG     PG  GPPG P  P P   +        M       G  S   
Sbjct: 156 GPQGIDGEPGVPGQ----PGAPGPPGHPSHPGPDGLSRPFSA--QMAGLDEKSGLGSQVG 209

Query: 292 MGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKN----SPNNISGISNPPGTPRDDGEL 347
           + PGS GP+G  G        G  G     G P +     P    G   PPG P +DGE 
Sbjct: 210 LMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEP 269

Query: 348 GGN 350
           G N
Sbjct: 270 GRN 272



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 54/184 (29%), Positives = 66/184 (35%), Gaps = 40/184 (21%)

Query: 108  NDGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQ-PL---- 160
            NDG PG  G +     +G PG    P +Q  P  P  +  P      G PG++ P+    
Sbjct: 1054 NDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPG 1113

Query: 161  ------LPNSMDPTR------------QQGHPNMGGSMQRMNPPRGMGPMG----PGPQN 198
                  LP    P              Q+GH    G      PP   G  G    PGP  
Sbjct: 1114 RAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGP-- 1171

Query: 199  YGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGT 258
               G R PP  +GP+  G    PG   P   P    S+  +        GPPG  GPPG 
Sbjct: 1172 --FGPRGPPGPVGPS--GKEGNPGPLGPIGPPGVRGSVGEAGPE-----GPPGEPGPPGP 1222

Query: 259  PIMP 262
            P  P
Sbjct: 1223 PGPP 1226


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 85/280 (30%), Positives = 102/280 (36%), Gaps = 49/280 (17%)

Query: 93   SAAAAPSPVLGNIPPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNP---------S 141
            S AA P    G  P +DG  G P P GF    GPPG +P P  Q  P            +
Sbjct: 1317 SGAAGPPGPKGP-PGDDGPKGSPGPVGFPGDPGPPG-EPGPAGQDGPPGDKGDDGEPGQT 1374

Query: 142  SMMGPHSQP-PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP--GPQN 198
               GP  +P P G PG +   P    P  +QG     G      PP   GP+GP   P  
Sbjct: 1375 GSPGPTGEPGPSGPPGKRGP-PGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGK 1433

Query: 199  YG-SGMRPPPNSLG----PAMPGINMGPGAGRPWPNPN-SANSIPYSSSS-PGTY--VGP 249
             G  G+R  P  +G    P  PG +  PG   P   P    +S P      PG    +GP
Sbjct: 1434 PGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGP 1493

Query: 250  PGGGGPPGTPIMPSPADSTN--SSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGME 307
            PG  G  G   +P P  S+       I     P+ P G     P  PG  GP G  G   
Sbjct: 1494 PGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGP----PGLPGPPGPKGAKGSSG 1549

Query: 308  PHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGEL 347
            P                   P   +G   PPG P   GE+
Sbjct: 1550 P-----------------TGPKGEAGHPGPPGPPGPPGEV 1572



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 63/185 (34%), Positives = 75/185 (40%), Gaps = 23/185 (12%)

Query: 98   PSPVLGNIPPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVP 155
            P    G I P  G PG P P G     GP G Q  P   P P  P   MGP      G+P
Sbjct: 1418 PPGKTGPIGPQ-GAPGKPGPDGLRGIPGPVGEQGLP-GSPGPDGPPGPMGPP-----GLP 1470

Query: 156  GTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRPPPNSLG 211
            G    L     P  ++GHP + G +    PP   G  G    PGPQ   SG +      G
Sbjct: 1471 G----LKGDSGPKGEKGHPGLIGLI---GPPGEQGEKGDRGLPGPQG-SSGPKGEQGITG 1522

Query: 212  PAMPGINMGPGA--GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTN 269
            P+ P    GP    G P P     +S P        + GPPG  GPPG  I P P  ++ 
Sbjct: 1523 PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASR 1582

Query: 270  SSDNI 274
            +  NI
Sbjct: 1583 TRRNI 1587



 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 78/279 (27%), Positives = 95/279 (34%), Gaps = 49/279 (17%)

Query: 109 DGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMD 166
           DG PG  G + P    GPPG Q +P AQ  P    ++  P  + P G PG  P +P +  
Sbjct: 702 DGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGL-PGMPGADG 760

Query: 167 PTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNY--GSGMRPPPNSLG----PAMPGI-- 217
           P    G     G      PP   GP+G PGP+      G+R    + G       PG   
Sbjct: 761 PPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKG 820

Query: 218 ---------NMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADST 268
                     +GP   R    P         +  PG  +GPPG  G  G P +P      
Sbjct: 821 DMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGP-LGPPGEKGKLGVPGLPGYPGRQ 879

Query: 269 NSSDNI----YTMIN--------PVPPGGSRSNFPMGP----------GSDGPMGGMGGM 306
               +I    +   N        P  PG      P GP          G  GP G  GG 
Sbjct: 880 GPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGD 939

Query: 307 EPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 345
            P    G  G     G     P    G   PPG P  DG
Sbjct: 940 GPAGPPGERGPNGPQG-----PTGFPGPKGPPGPPGKDG 973



 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 85/295 (28%), Positives = 98/295 (33%), Gaps = 65/295 (22%)

Query: 110  GMPGGPIPPGF--FQGPPGS--------QPSPHAQPPPHNPSSMMGPHSQ--PPGGV--P 155
            G PG P P G     GPPG         Q  P   P P  PS   G      PPGG+  P
Sbjct: 1219 GFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNP 1278

Query: 156  GT-----------QPLLPNS---MDPTRQQGHPNMGGSMQRMNPPRGMGPMG-------P 194
            G            +P LP       P  ++G     G      PP   GP G       P
Sbjct: 1279 GAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSP 1338

Query: 195  GPQNYGSGMRPP--PNSLG----PAMPGINMGPG-AGRPWPNPNSANSIPYSSSSPGTYV 247
            GP  +     PP  P   G    P   G +  PG  G P P      S P     P    
Sbjct: 1339 GPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPA 1398

Query: 248  GPPGGGG------------PPGT--PIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG 293
            GP G  G            PPG   PI P  A      D +  +  PV   G     P  
Sbjct: 1399 GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQG----LPGS 1454

Query: 294  PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
            PG DGP G MG      + G  G     G P      + G+  PPG   + G+ G
Sbjct: 1455 PGPDGPPGPMGPPGLPGLKGDSGPKGEKGHP-----GLIGLIGPPGEQGEKGDRG 1504



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 74/251 (29%), Positives = 88/251 (35%), Gaps = 28/251 (11%)

Query: 110  GMPGGPIPPGFFQGP-PGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPT 168
            G+ G P P G   G  P   P       P  P+   GP   P  G PG   L  +     
Sbjct: 925  GITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPP--GPPGKDGLPGH----P 978

Query: 169  RQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPG-AGRPW 227
             Q+G     G      PP  +GP GP  +    G R  P   GP  PG    PG AG+  
Sbjct: 979  GQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGP--PGEQGLPGLAGK-- 1034

Query: 228  PNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSR 287
                     P  +  PG   GPPG  G PG   +P P  +     N      P P G   
Sbjct: 1035 ---EGTKGDPGPAGLPGK-DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPG 1090

Query: 288  SNFPMG----------PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNP 337
               P G          PG  GP G  G        G  G    DGL    P  + G + P
Sbjct: 1091 ERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGL--QGPVGLPGPAGP 1148

Query: 338  PGTPRDDGELG 348
             G P +DG+ G
Sbjct: 1149 VGPPGEDGDKG 1159



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 84/290 (28%), Positives = 99/290 (34%), Gaps = 49/290 (16%)

Query: 94   AAAAPSPVLGNIPPND----GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQ 149
            A   P P     PP +    G PG P  PG   GPPG    P  + PP        P  Q
Sbjct: 728  AQGLPGPQGAIGPPGEKGPLGKPGLPGMPGA-DGPPGH---PGKEGPPGEKGGQGPPGPQ 783

Query: 150  PPGGVPGTQPL--------LPNSMDPTRQQGHPNMGGSM------QRMNP--PRG----M 189
             P G PG + +        L  +     + G P   G M        + P  PRG     
Sbjct: 784  GPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPE 843

Query: 190  GPMGPGPQNYGSGMRPPPNSLG----PAMPGI--NMGPGAGRPWPNPNSANSIPYSSSSP 243
            GP G G  N   G   PP   G    P +PG     GP     +P    AN       +P
Sbjct: 844  GPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTP 903

Query: 244  GTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP----GSDGP 299
            G   GP G  GP G      P   T           P P G S  + P GP    G +GP
Sbjct: 904  GK-PGPRGQRGPTGPRGERGPRGITG---------KPGPKGNSGGDGPAGPPGERGPNGP 953

Query: 300  MGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGISNPPGTPRDDGELG 348
             G  G   P    G  G   + G P +       G + PPG P   G  G
Sbjct: 954  QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQG 1003



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 76/275 (27%), Positives = 95/275 (34%), Gaps = 48/275 (17%)

Query: 110  GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQ-PLLPNSMDPT 168
            G+PG P P G   GP G + +P  +  P  P+   G   Q P G+PG   P+ P   D  
Sbjct: 1102 GIPGRPGPQGP-PGPAGEKGAP-GEKGPQGPAGRDG--LQGPVGLPGPAGPVGPPGEDGD 1157

Query: 169  RQQ-GHPNMGGSMQ---RMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAG 224
            + + G P   GS        PP   GP GP  Q   SG                     G
Sbjct: 1158 KGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG-------------------ADG 1198

Query: 225  RPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG 284
             P P              P  + GPP   GP G   +P P      + ++  M  P PPG
Sbjct: 1199 EPGPRGQQGLFGQKGDEGPRGFPGPP---GPVGLQGLPGPPGEKGETGDVGQMGPPGPPG 1255

Query: 285  -GSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP----------------KNS 327
                S  P   G  GP GG+G        G  G     GLP                ++ 
Sbjct: 1256 PRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESG 1315

Query: 328  PNNISGISNPPGTPRDDGELGGNFLHSFQNDNYSP 362
            P+  +G   P G P DDG  G      F  D   P
Sbjct: 1316 PSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPP 1350



 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 78/297 (26%), Positives = 97/297 (32%), Gaps = 66/297 (22%)

Query: 106  PPNDGMPGGPIPPGFFQGPPGS--QPSPHAQPPPHNPSSMMGPHSQP-PGGVPGTQPLLP 162
            PP    P GPI      GP G+  +P P  Q          GP   P P G  G Q L  
Sbjct: 1178 PPGPTGPQGPIGQ---PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGL-- 1232

Query: 163  NSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLG----------- 211
                P  ++G     G + +M PP   GP GP       G + PP  +G           
Sbjct: 1233 --PGPPGEKGET---GDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEP 1287

Query: 212  -----PAMPGINMGPG----------------AGRPWPNPNSANSIPYSSSSPGTYVGPP 250
                 P +PG    PG                AG P P     +  P  S  P  + G P
Sbjct: 1288 GEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDP 1347

Query: 251  GGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHH 310
            G  G PG      P              +P P G    + P  PG  GP G  G      
Sbjct: 1348 GPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGP--PGKRGPPGPAGPEGRQG 1405

Query: 311  MNGSLGSGDIDGLP-------------KNSPNNISGISNP------PGTPRDDGELG 348
              G+ G   ++G P             K  P+ + GI  P      PG+P  DG  G
Sbjct: 1406 EKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPG 1462



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 64/249 (25%), Positives = 81/249 (32%), Gaps = 54/249 (21%)

Query: 110 GMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPL------- 160
           G PG   PPG    +G PG          P  P  + GP    P G PG +         
Sbjct: 568 GRPGPVGPPGSGGLKGEPGDVG-------PQGPRGVQGPPG--PAGKPGRRGRAGSDGAR 618

Query: 161 -LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINM 219
            +P    P   +G   + G           GP GP       G R     +GP   G+  
Sbjct: 619 GMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPR--GLPG 676

Query: 220 GPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMIN 279
            PG                    P   +GP G  GPPG P +           N+     
Sbjct: 677 EPG--------------------PRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGE 716

Query: 280 PVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPG 339
           P PPG   +     PG+ G  G  G + P    G LG   + G+P        G   PPG
Sbjct: 717 PGPPGQQGN-----PGAQGLPGPQGAIGPPGEKGPLGKPGLPGMP--------GADGPPG 763

Query: 340 TPRDDGELG 348
            P  +G  G
Sbjct: 764 HPGKEGPPG 772



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 78/295 (26%), Positives = 103/295 (34%), Gaps = 58/295 (19%)

Query: 94  AAAAPSPVLGNIPPNDGMPGGPIPPGFF-----------QGPPGSQPSPHAQPPPHNPSS 142
           A   P  ++   P  +G  G P PPG             +GPPG    P A   P  P +
Sbjct: 459 AIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGT 518

Query: 143 M-MGPHSQPPGGVPGTQPLLPNSMDPTR----QQGHPNMGGSMQRMNPPRGMGPMGPGPQ 197
           M M P     GG  G++  + ++ +       QQ    + G    M      GP+GP   
Sbjct: 519 MLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPG- 577

Query: 198 NYGSGMRPPPNSLGPAMP-GINMGPG-AGRPW----PNPNSANSIPYSSSSPGT------ 245
               G++  P  +GP  P G+   PG AG+P        + A  +P  +   G       
Sbjct: 578 --SGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGL 635

Query: 246 --------YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSD 297
                   + G PG  GPPG      P D     D+       V P G        PG  
Sbjct: 636 AGLPGEKGHRGDPGPSGPPG-----PPGDDGERGDD-----GEVGPRGL-------PGEP 678

Query: 298 GPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFL 352
           GP G +G   P    G  G   +DG P   P    G    PG P   G  G   L
Sbjct: 679 GPRGLLGPKGPPGPPGPPGVTGMDGQP--GPKGNVGPQGEPGPPGQQGNPGAQGL 731



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 69/271 (25%), Positives = 86/271 (31%), Gaps = 56/271 (20%)

Query: 107 PNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMD 166
           P D   G  IP         S P+P   PP      + G  ++        + L  N  D
Sbjct: 367 PTDPGAGAEIPTSTADTSNSSNPAP---PPGEGADDLEGEFTEET-----IRNLDENYYD 418

Query: 167 PTRQQGHPNMGGSMQRMNPPRGMGPMGPG-PQNYGS---GMRPPPNSLGPAMPGINMGPG 222
           P                +P      +GPG P N  +   G+  P    G       + PG
Sbjct: 419 PY--------------YDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPG 464

Query: 223 A---GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMIN 279
               G P P   +    P  +  P   VG PG  GPPG P +P  AD          M+ 
Sbjct: 465 MLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPG-ADGLPGPPGTMLML- 522

Query: 280 PVPPGGSRSNFPMGP---------------------GSDGPMGGMGGMEPHHMNGSLGSG 318
           P   GG       GP                     G  GPMG  G   P    G  GSG
Sbjct: 523 PFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGP---VGPPGSG 579

Query: 319 DIDGLPKN-SPNNISGISNPPGTPRDDGELG 348
            + G P +  P    G+  PPG     G  G
Sbjct: 580 GLKGEPGDVGPQGPRGVQGPPGPAGKPGRRG 610


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 64/202 (31%), Positives = 83/202 (41%), Gaps = 22/202 (10%)

Query: 98   PSPVLG-NIPPNDGMPGGPIPP-----GFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPP 151
            P P+ G  IPP   +PG  IPP     G    PP   P     PPP  P + + P    P
Sbjct: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1136

Query: 152  G-GVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL 210
            G G+P   PL    + P      P + G+     PP     + P P   G G+ PPP   
Sbjct: 1137 GAGIPPPPPLPRVGIPPP-----PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1191

Query: 211  GPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPP-------GTPIMPS 263
            G  +P     PGAG P P P     IP + + P   + PPG G PP       G P++P 
Sbjct: 1192 GVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPP---LPPPGTGIPPPPLLPVSGPPLLPQ 1248

Query: 264  PADSTNSSDNIYTMINPVPPGG 285
               ST  +  +   + P  P G
Sbjct: 1249 VGSSTLPTPQVCGFLPPPLPSG 1270



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 80/276 (28%), Positives = 103/276 (37%), Gaps = 47/276 (17%)

Query: 93   SAAAAPSPVLGNI---PPNDGMPGGPIPP-------GFFQGPPGSQPSPHAQPPPHNPSS 142
            +A   P P+ G     PP   +PG  IPP       G    PP   P     PPP  P +
Sbjct: 894  TAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP--LPGAGIPPPPPLPGA 951

Query: 143  MMGPHSQPPG-GVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGS 201
             + P    PG G+P   PL    + P      P + G+     PP     + P P   G+
Sbjct: 952  AIPPPPPLPGAGIPLPPPLPGAGIPPP-----PPLPGAGIPPPPPLPGAGIPPPPPLPGA 1006

Query: 202  GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP----PGGGGPPG 257
            G+ PPP   G  +P     PGAG P P P     IP     PG  + P    PG G PP 
Sbjct: 1007 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1066

Query: 258  TPI----MPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDG-------PMGGMGGM 306
             P+    +P P     +         P PP    +  P  P   G       P+ G G  
Sbjct: 1067 PPLPGAGIPPPPPLPGAG-------IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIP 1119

Query: 307  EPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPR 342
             P  + G+       G+P   P   +GI  PP  PR
Sbjct: 1120 PPPPLPGA-------GIPPPPPLPGAGIPPPPPLPR 1148



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 77/285 (27%), Positives = 103/285 (36%), Gaps = 38/285 (13%)

Query: 65   VFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGP 124
            + W      P  +     S+E +  H++S ++A      NIP    +P            
Sbjct: 816  LLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSC-NIPSPPPLP--------CTES 866

Query: 125  PGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMN 184
              S P     PPP  P   M   + P   +P   PL    M P      P  G       
Sbjct: 867  SSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPL 926

Query: 185  PPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPG 244
            P  G+ P+ P P   G+G+ PPP   G A+P     PGAG P P P     IP     PG
Sbjct: 927  PGAGILPLPPLP---GAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPG 983

Query: 245  TYVGP----PGGGGPPGTPI----MPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGS 296
              + P    PG G PP  P+    +P P     +         P PP    +  P  P  
Sbjct: 984  AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-------IPPPPPLPGAGIPPPP-- 1034

Query: 297  DGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTP 341
              P+ G G   P  + G+       G+P   P   +GI  PP  P
Sbjct: 1035 --PLPGAGIPPPPPLPGA-------GIPPPPPLPGAGIPPPPPLP 1070



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 59/181 (32%), Positives = 71/181 (39%), Gaps = 15/181 (8%)

Query: 98   PSPVLG-NIPPNDGMPGGPIPP-----GFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPP 151
            P P+ G  IPP   +PG  IPP     G    PP   P     PPP  P   + P    P
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1114

Query: 152  G-GVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL 210
            G G+P   PL    + P      P + G+     PP     + P P   G+G+ PPP   
Sbjct: 1115 GAGIPPPPPLPGAGIPPP-----PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP 1169

Query: 211  GPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPP---GGGGPPGTPIMPSPADS 267
            G  +P     PG G P P P     IP     PG  + PP    G G P  P  P P   
Sbjct: 1170 GAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPG 1229

Query: 268  T 268
            T
Sbjct: 1230 T 1230



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 41/131 (31%), Positives = 47/131 (35%), Gaps = 31/131 (23%)

Query: 98   PSPVLGNIPPND----GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPG- 152
            P P +G  PP      G+P  P  PG    PP   P     P P        P   PPG 
Sbjct: 1178 PLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP-------APPLPPPGT 1230

Query: 153  GVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGP 212
            G+P   PLLP S  P      P +G S              P PQ    G  PPP   G 
Sbjct: 1231 GIP-PPPLLPVSGPPLL----PQVGSSTL------------PTPQ--VCGFLPPPLPSGL 1271

Query: 213  AMPGINMGPGA 223
               G+N   G+
Sbjct: 1272 FGLGMNQDKGS 1282


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
           sapiens]
          Length = 1424

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 85/268 (31%), Positives = 100/268 (37%), Gaps = 51/268 (19%)

Query: 102 LGNIPPNDGMPGGPIPPGFF--------QGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGG 153
           L  IP   G+ G P P G          QGPPG   SP   P P  P+   G   Q   G
Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP-GSPGPAGPAGPPGYGPQGEPG 625

Query: 154 VPGTQPLLPNSMDPTRQQG-HPNMGGSMQRMNPPRGMGPMG-PGPQNYGSGMRPP--PNS 209
           + GTQ + P +  P  + G    +  S     PP   GP G PGPQ       PP  P S
Sbjct: 626 LQGTQGV-PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG------PPGIPGS 678

Query: 210 LG----PAMPGINMGPGA---GRPWP-NPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIM 261
           LG    P +PG +  PG    G P P  P      P +  S    +G PG  G PG P  
Sbjct: 679 LGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS----LGCPGKMGEPGLPGK 734

Query: 262 PSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDID 321
           P                 P   G      P GPG+ G  G  G    H   G +G   + 
Sbjct: 735 PGL---------------PGAKGEPAVAMPGGPGTPGFPGERGNSGEH---GEIGLPGLP 776

Query: 322 GLPKNSPN-NISGISNPPGTPRDDGELG 348
           GLP    N  + G    PG P   GE G
Sbjct: 777 GLPGTPGNEGLDGPRGDPGQPGPPGEQG 804



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 90/303 (29%), Positives = 109/303 (35%), Gaps = 76/303 (25%)

Query: 96   AAPSPVLGNIPPNDGMPGGPIPPGFFQ--------GPPGSQPSPHAQPPPHNPSSM---- 143
            A P    G+ P + G+PG P P G           GPPG +  P     P +P  M    
Sbjct: 1097 AGPEGAPGS-PGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155

Query: 144  -------MGPHSQ---------PPG--GVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNP 185
                    GP  +         PPG  G PG Q    +   P    G P + G    M  
Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP----GFPGLPGRKGAMGD 1211

Query: 186  PRGMGPMG----PGPQNYGSGMRP-PPNSLGPAMPGINMGPGAGRPWPNPNSANSI---- 236
                GP G    PGP      + P    + GP  PG    PGA  P P P  ++ I    
Sbjct: 1212 AGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGP--PGSRGSPGAPGP-PGPPGSHVIGIKG 1268

Query: 237  -------PYSSSSPGTY--VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--G 285
                   P     PGT   +GPPG  G PGTP +P P                  PG  G
Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGF---------PGVKG 1319

Query: 286  SRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 345
             + N P   GS GP G +G   P  + G  G+  I  LP        G   PPGTP + G
Sbjct: 1320 EKGN-PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP--------GSPGPPGTPGEPG 1370

Query: 346  ELG 348
              G
Sbjct: 1371 MQG 1373



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 76/267 (28%), Positives = 92/267 (34%), Gaps = 34/267 (12%)

Query: 106 PPNDGMPGGPIPPGFFQGPPG--SQPSPHAQPP-----PHNPSSMMGPHSQPPGGVPGTQ 158
           P N G+PG P  PG  QG PG   +     QP      P +P     P  +   G+PGT 
Sbjct: 516 PGNTGLPGFPGFPGA-QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP 574

Query: 159 PL--LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYGSGMRPPPNSLGPAMP 215
            +  LP         G     G       P   GP GP GP  YG     P     P + 
Sbjct: 575 GVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYG-----PQGE--PGLQ 627

Query: 216 GINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIY 275
           G    PGA  P         +  S+  PG    PPG   PPG P  P P        ++ 
Sbjct: 628 GTQGVPGAPGPPGEAGPRGELSVSTPVPG----PPG---PPGPPGHPGPQGPPGIPGSLG 680

Query: 276 TMINPVPPGGSRS------NFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDI---DGLPKN 326
              +P  PG           FP  PG  G  G  G        G +G   +    GLP  
Sbjct: 681 KCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA 740

Query: 327 SPNNISGISNPPGTPRDDGELGGNFLH 353
                  +   PGTP   GE G +  H
Sbjct: 741 KGEPAVAMPGGPGTPGFPGERGNSGEH 767



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 84/301 (27%), Positives = 101/301 (33%), Gaps = 55/301 (18%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-- 150
           S   A SP    +P + G PG P    F +GPPG    P     P  P  + GP  +P  
Sbjct: 419 SPGCAGSP---GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGL 474

Query: 151 ----------PGGVPGTQPL-----LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-P 194
                     P G+PG   L     +P        +G P   G+      P   G  G P
Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534

Query: 195 GPQNYGSGMRPPPNSLG-PAMPGINMGPG-------------AGRPWPNPNSANS----- 235
           G +        P   +G P  PG+   PG              G P P    A S     
Sbjct: 535 GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 236 --IPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNF--- 290
              P    SPG+  GP G  GPPG    P        +  +     P    G R      
Sbjct: 595 QGPPGDPGSPGS-PGPAGPAGPPG--YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVS 651

Query: 291 ---PMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGIS--NPPGTPRDD 344
              P  PG  GP G  G   P  + GSLG     GLP  +    I GI    PPG   D 
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQ 711

Query: 345 G 345
           G
Sbjct: 712 G 712



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 82/314 (26%), Positives = 107/314 (34%), Gaps = 71/314 (22%)

Query: 100  PVLGNIPPNDGM------PGGPIPPGFFQGPPG----------SQPSPHAQPPPHNPSSM 143
            P L   P N+G+      PG P PPG  QGPPG            P  +           
Sbjct: 776  PGLPGTPGNEGLDGPRGDPGQPGPPGE-QGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834

Query: 144  MGPHSQPPGGVPGTQPL-LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSG 202
             GP   P  G+PG      P         GH    G + +   P   G +GP  ++   G
Sbjct: 835  TGPKGDP--GIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG 892

Query: 203  MRPPPNSLGPAMPGINMG-------------------PGA-----GRPWPNPNSANSIPY 238
            M   P ++GP  P  N G                   PGA      +  P P+  + +  
Sbjct: 893  MMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIG 952

Query: 239  SSSSPGT--YVGPPGGGGPPGTPIM---------PSPADSTNSSDNIYTMINPVPPG--- 284
                PG   + G PG  G  G P M         P PA       ++ +  NP  PG   
Sbjct: 953  DKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012

Query: 285  --GSRSNFPMGPGSDGPMGGMG--------GMEPHHMNGSLGSGDIDGLPKNSPNNISGI 334
              GS  N  M PGS G  G +G        G+   H  G  G     G  + +     G 
Sbjct: 1013 IPGSMGNMGM-PGSKGKRGTLGFPGRAGRPGLPGIH--GLQGDKGEPGYSEGTRPGPPGP 1069

Query: 335  SNPPGTPRDDGELG 348
            +  PG P D G+ G
Sbjct: 1070 TGDPGLPGDMGKKG 1083



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 83/294 (28%), Positives = 98/294 (33%), Gaps = 58/294 (19%)

Query: 91  DYSAAAAPSPVLGNIPPNDGMPGGPIPPGFF--QGPPGSQPSPHAQPPPHNPSSMMGPH- 147
           D    A   P L   P   G+PG P  PG     GPPG    P A   P  P   MG   
Sbjct: 164 DIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM-GPRGPKGHMGERV 222

Query: 148 -----------SQPPGGVPGTQPL-LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPG 195
                         P G PGT  + L    + T  +G     G+M    PP   GP G  
Sbjct: 223 IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP---GPSGLP 279

Query: 196 PQNYGS--------GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTY 246
            ++YGS        G++  P   G P  PG + G    R +P     + I          
Sbjct: 280 GESYGSEKGAPGDPGLQGKPGKDGVPGFPG-SEGVKGNRGFPGLMGEDGIKGQKGD---- 334

Query: 247 VGPPGGGGP------------PGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP 294
           +GPPG  GP             GTP  P P  +            P  PG SR      P
Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAP 394

Query: 295 GSDGPMGGMG-----GMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRD 343
           G  G  G  G     G +     GS G     GLP        G   PPG P D
Sbjct: 395 GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLP--------GSPGPPGPPGD 440



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 73/229 (31%), Positives = 83/229 (36%), Gaps = 55/229 (24%)

Query: 109  DGMPGGPIPPGFF-------QGPPGSQPSPHAQPPPHNPSSMM-------GPHSQP-PGG 153
            +G PG P  PG         +GPPGS+ SP A  PP  P S +       G    P P G
Sbjct: 1221 EGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG 1280

Query: 154  VPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGS--GMRPPPN--- 208
             PGT       M P  + G P   G    +  PRG     PG Q +    G +  P    
Sbjct: 1281 PPGTA----GDMGPPGRLGAPGTPG----LPGPRG----DPGFQGFPGVKGEKGNPGFLG 1328

Query: 209  SLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADST 268
            S+GP  P    GP   R  P      S+P S        GPPG  G PG    P P    
Sbjct: 1329 SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSP-------GPPGTPGEPGMQGEPGP---- 1377

Query: 269  NSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLG 316
                       P PPG      P G PG DG  G  G        GS G
Sbjct: 1378 -----------PGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 80/292 (27%), Positives = 100/292 (34%), Gaps = 69/292 (23%)

Query: 106 PPND-GMPGGPIP------PGFF-QGPPGSQ--------PSPHAQPPPHNPSSMMGPHSQ 149
           PP D G PG P P      PG+  QG PG Q        P P  +  P    S+  P   
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656

Query: 150 PP--GGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPP 207
           PP   G PG              QG P + GS+ +   P   GP G  P   G G   PP
Sbjct: 657 PPGPPGPPG----------HPGPQGPPGIPGSLGKCGDPGLPGPDGE-PGIPGIGFPGPP 705

Query: 208 NSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT----YVGPPGGGGPPGTPIMP 262
              G    PG     G     P       +P     PG      V  PGG G PG     
Sbjct: 706 GPKGDQGFPGTKGSLGC----PGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG----- 756

Query: 263 SPADSTNSSDNIYTMINPVP-----PGGSRSNFPMG-------PGSDGPMG--------- 301
            P +  NS ++    +  +P     PG    + P G       PG  GP G         
Sbjct: 757 FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 302 ----GMGGMEPHH-MNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
               G+ G++      G  G     G+P    +   G +  PG P   GE+G
Sbjct: 817 QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG 868



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 77/258 (29%), Positives = 86/258 (33%), Gaps = 48/258 (18%)

Query: 95  AAAPSPVLGNIPPN------DGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHS 148
           AAAP+   G +  +      DG  G     GF  GPPGS      Q     P  + GP  
Sbjct: 22  AAAPAASKGCVCKDKGQCFCDGAKGEKGEKGF-PGPPGSP----GQKGFTGPEGLPGP-- 74

Query: 149 QPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMR 204
           Q P G PG  P L  S       G P   GS      P   GP G    PG         
Sbjct: 75  QGPKGFPGL-PGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133

Query: 205 PP--PNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP 262
            P  P +LG   PGI    G       P     I   +       G PG  G PG P  P
Sbjct: 134 FPGLPGTLG--YPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191

Query: 263 SPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDG 322
            P               P PPG     FP   G  GP G MG      + G  G   + G
Sbjct: 192 GPVGP------------PGPPGFF--GFPGAMGPRGPKGHMG----ERVIGHKGERGVKG 233

Query: 323 LPKNSPNNISGISNPPGT 340
           L        +G   PPGT
Sbjct: 234 L--------TGPPGPPGT 243



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 80/261 (30%), Positives = 90/261 (34%), Gaps = 57/261 (21%)

Query: 100  PVLGNIPP---NDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPG 156
            P L  IP    N GMPG     G   G PG    P   P  H      G     PG   G
Sbjct: 1008 PGLRGIPGSMGNMGMPGSKGKRGTL-GFPGRAGRP-GLPGIHGLQGDKGE----PGYSEG 1061

Query: 157  TQPLLPNSMDPTRQQGHP-NMG--GSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPA 213
            T+P  P    PT   G P +MG  G M +  PP  +GP GP            P S  P 
Sbjct: 1062 TRPGPPG---PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP---------EGAPGS--PG 1107

Query: 214  MPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP-SPADSTNSSD 272
             PG+      G+P P+ +               +GPPG  GPPG P  P SP       D
Sbjct: 1108 SPGL-----PGKPGPHGD------LGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156

Query: 273  NIYTMINPVPPG--GSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP------ 324
                 I P P G  G        PG  G  G  G        G  G+    GLP      
Sbjct: 1157 QGRDGI-PGPAGEKGETGLLRAPPGPRGNPGAQGA------KGDRGAPGFPGLPGRKGAM 1209

Query: 325  ----KNSPNNISGISNPPGTP 341
                   P  I G   PPG P
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLP 1230



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 89/337 (26%), Positives = 109/337 (32%), Gaps = 85/337 (25%)

Query: 81  EHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGG---PIPPGFFQGPPGSQPSPHAQPPP 137
           E   E  A  D     AP P    +P   G PG    P PPGFF  P    P     P  
Sbjct: 162 EEDIELDAKGDPGLPGAPGPQ--GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRG---PKG 216

Query: 138 HNPSSMMGPHSQP-------PGGVPGTQPLLPNSMDP-TRQQGHPNMGGSMQRMNPPRGM 189
           H    ++G   +        P G PGT  +     D  T  +G     G+M    PP   
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP--- 273

Query: 190 GPMGPGPQNYGS--------GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSI---- 236
           GP G   ++YGS        G++  P   G P  PG + G    R +P     + I    
Sbjct: 274 GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPG-SEGVKGNRGFPGLMGEDGIKGQK 332

Query: 237 ----PYSSSSPGTYV---------------------GPPGGGGPPGTPIMPSP------- 264
               P     P  Y                      GP G  GPPG P  P         
Sbjct: 333 GDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRG 392

Query: 265 ---------ADSTNSSDNIYTMINPVPPGGSRS-NFPMGPGSDGPMGGM----GGMEPHH 310
                    +           M  P  PG + S   P  PG  GP G +    G    H 
Sbjct: 393 APGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHG 452

Query: 311 MNGSLGSGDIDGL--PKNSPNNISG----ISNPPGTP 341
           + G LGS  I G+  PK  P  +      I  PPG P
Sbjct: 453 LPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLP 489



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 44/127 (34%), Positives = 52/127 (40%), Gaps = 17/127 (13%)

Query: 106  PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSM--------MGPHSQPPG--GVP 155
            P   G PG P  PG  +G PG Q  P  +    NP  +        +GP   PPG  G P
Sbjct: 1291 PGRLGAPGTPGLPGP-RGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKG-PPGVRGDP 1348

Query: 156  GTQPL--LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPA 213
            GT  +  LP S  P    G P M G      PP  +GP GP  +    G    P + GPA
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGK---PGKDGKPGTPGPA 1405

Query: 214  MPGINMG 220
                N G
Sbjct: 1406 GEKGNKG 1412


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
           sapiens]
          Length = 1494

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 85/268 (31%), Positives = 100/268 (37%), Gaps = 51/268 (19%)

Query: 102 LGNIPPNDGMPGGPIPPGFF--------QGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGG 153
           L  IP   G+ G P P G          QGPPG   SP   P P  P+   G   Q   G
Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP-GSPGPAGPAGPPGYGPQGEPG 625

Query: 154 VPGTQPLLPNSMDPTRQQG-HPNMGGSMQRMNPPRGMGPMG-PGPQNYGSGMRPP--PNS 209
           + GTQ + P +  P  + G    +  S     PP   GP G PGPQ       PP  P S
Sbjct: 626 LQGTQGV-PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG------PPGIPGS 678

Query: 210 LG----PAMPGINMGPGA---GRPWP-NPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIM 261
           LG    P +PG +  PG    G P P  P      P +  S    +G PG  G PG P  
Sbjct: 679 LGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS----LGCPGKMGEPGLPGK 734

Query: 262 PSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDID 321
           P                 P   G      P GPG+ G  G  G    H   G +G   + 
Sbjct: 735 PGL---------------PGAKGEPAVAMPGGPGTPGFPGERGNSGEH---GEIGLPGLP 776

Query: 322 GLPKNSPN-NISGISNPPGTPRDDGELG 348
           GLP    N  + G    PG P   GE G
Sbjct: 777 GLPGTPGNEGLDGPRGDPGQPGPPGEQG 804



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 90/303 (29%), Positives = 109/303 (35%), Gaps = 76/303 (25%)

Query: 96   AAPSPVLGNIPPNDGMPGGPIPPGFFQ--------GPPGSQPSPHAQPPPHNPSSM---- 143
            A P    G+ P + G+PG P P G           GPPG +  P     P +P  M    
Sbjct: 1097 AGPEGAPGS-PGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155

Query: 144  -------MGPHSQ---------PPG--GVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNP 185
                    GP  +         PPG  G PG Q    +   P    G P + G    M  
Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP----GFPGLPGRKGAMGD 1211

Query: 186  PRGMGPMG----PGPQNYGSGMRP-PPNSLGPAMPGINMGPGAGRPWPNPNSANSI---- 236
                GP G    PGP      + P    + GP  PG    PGA  P P P  ++ I    
Sbjct: 1212 AGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGP--PGSRGSPGAPGP-PGPPGSHVIGIKG 1268

Query: 237  -------PYSSSSPGTY--VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--G 285
                   P     PGT   +GPPG  G PGTP +P P                  PG  G
Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGF---------PGVKG 1319

Query: 286  SRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 345
             + N P   GS GP G +G   P  + G  G+  I  LP        G   PPGTP + G
Sbjct: 1320 EKGN-PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP--------GSPGPPGTPGEPG 1370

Query: 346  ELG 348
              G
Sbjct: 1371 MQG 1373



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 76/267 (28%), Positives = 92/267 (34%), Gaps = 34/267 (12%)

Query: 106 PPNDGMPGGPIPPGFFQGPPG--SQPSPHAQPP-----PHNPSSMMGPHSQPPGGVPGTQ 158
           P N G+PG P  PG  QG PG   +     QP      P +P     P  +   G+PGT 
Sbjct: 516 PGNTGLPGFPGFPGA-QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP 574

Query: 159 PL--LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYGSGMRPPPNSLGPAMP 215
            +  LP         G     G       P   GP GP GP  YG     P     P + 
Sbjct: 575 GVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYG-----PQGE--PGLQ 627

Query: 216 GINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIY 275
           G    PGA  P         +  S+  PG    PPG   PPG P  P P        ++ 
Sbjct: 628 GTQGVPGAPGPPGEAGPRGELSVSTPVPG----PPG---PPGPPGHPGPQGPPGIPGSLG 680

Query: 276 TMINPVPPGGSRS------NFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDI---DGLPKN 326
              +P  PG           FP  PG  G  G  G        G +G   +    GLP  
Sbjct: 681 KCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA 740

Query: 327 SPNNISGISNPPGTPRDDGELGGNFLH 353
                  +   PGTP   GE G +  H
Sbjct: 741 KGEPAVAMPGGPGTPGFPGERGNSGEH 767



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 74/235 (31%), Positives = 88/235 (37%), Gaps = 47/235 (20%)

Query: 109  DGMPGGPIPPGFF-------QGPPGSQPSPHAQPPPHNPSSMM-------GPHSQP-PGG 153
            +G PG P  PG         +GPPGS+ SP A  PP  P S +       G    P P G
Sbjct: 1221 EGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG 1280

Query: 154  VPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGS--GMRPPPN--- 208
             PGT       M P  + G P   G    +  PRG     PG Q +    G +  P    
Sbjct: 1281 PPGTA----GDMGPPGRLGAPGTPG----LPGPRG----DPGFQGFPGVKGEKGNPGFLG 1328

Query: 209  SLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADST 268
            S+GP  P    GP   R  P      S+P S   PGT  G PG  G PG P  P      
Sbjct: 1329 SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT-PGEPGMQGEPGPPGPPG----- 1382

Query: 269  NSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGL 323
                     + P  P G +      PG+ GP G  G        G  GS  + GL
Sbjct: 1383 --------NLGPCGPRG-KPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGL 1428



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 84/301 (27%), Positives = 101/301 (33%), Gaps = 55/301 (18%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-- 150
           S   A SP    +P + G PG P    F +GPPG    P     P  P  + GP  +P  
Sbjct: 419 SPGCAGSP---GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGL 474

Query: 151 ----------PGGVPGTQPL-----LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-P 194
                     P G+PG   L     +P        +G P   G+      P   G  G P
Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534

Query: 195 GPQNYGSGMRPPPNSLG-PAMPGINMGPG-------------AGRPWPNPNSANS----- 235
           G +        P   +G P  PG+   PG              G P P    A S     
Sbjct: 535 GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 236 --IPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNF--- 290
              P    SPG+  GP G  GPPG    P        +  +     P    G R      
Sbjct: 595 QGPPGDPGSPGS-PGPAGPAGPPG--YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVS 651

Query: 291 ---PMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGIS--NPPGTPRDD 344
              P  PG  GP G  G   P  + GSLG     GLP  +    I GI    PPG   D 
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQ 711

Query: 345 G 345
           G
Sbjct: 712 G 712



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 82/314 (26%), Positives = 107/314 (34%), Gaps = 71/314 (22%)

Query: 100  PVLGNIPPNDGM------PGGPIPPGFFQGPPG----------SQPSPHAQPPPHNPSSM 143
            P L   P N+G+      PG P PPG  QGPPG            P  +           
Sbjct: 776  PGLPGTPGNEGLDGPRGDPGQPGPPGE-QGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834

Query: 144  MGPHSQPPGGVPGTQPL-LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSG 202
             GP   P  G+PG      P         GH    G + +   P   G +GP  ++   G
Sbjct: 835  TGPKGDP--GIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG 892

Query: 203  MRPPPNSLGPAMPGINMG-------------------PGA-----GRPWPNPNSANSIPY 238
            M   P ++GP  P  N G                   PGA      +  P P+  + +  
Sbjct: 893  MMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIG 952

Query: 239  SSSSPGT--YVGPPGGGGPPGTPIM---------PSPADSTNSSDNIYTMINPVPPG--- 284
                PG   + G PG  G  G P M         P PA       ++ +  NP  PG   
Sbjct: 953  DKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012

Query: 285  --GSRSNFPMGPGSDGPMGGMG--------GMEPHHMNGSLGSGDIDGLPKNSPNNISGI 334
              GS  N  M PGS G  G +G        G+   H  G  G     G  + +     G 
Sbjct: 1013 IPGSMGNMGM-PGSKGKRGTLGFPGRAGRPGLPGIH--GLQGDKGEPGYSEGTRPGPPGP 1069

Query: 335  SNPPGTPRDDGELG 348
            +  PG P D G+ G
Sbjct: 1070 TGDPGLPGDMGKKG 1083



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 83/294 (28%), Positives = 98/294 (33%), Gaps = 58/294 (19%)

Query: 91  DYSAAAAPSPVLGNIPPNDGMPGGPIPPGFF--QGPPGSQPSPHAQPPPHNPSSMMGPH- 147
           D    A   P L   P   G+PG P  PG     GPPG    P A   P  P   MG   
Sbjct: 164 DIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM-GPRGPKGHMGERV 222

Query: 148 -----------SQPPGGVPGTQPL-LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPG 195
                         P G PGT  + L    + T  +G     G+M    PP   GP G  
Sbjct: 223 IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP---GPSGLP 279

Query: 196 PQNYGS--------GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTY 246
            ++YGS        G++  P   G P  PG + G    R +P     + I          
Sbjct: 280 GESYGSEKGAPGDPGLQGKPGKDGVPGFPG-SEGVKGNRGFPGLMGEDGIKGQKGD---- 334

Query: 247 VGPPGGGGP------------PGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP 294
           +GPPG  GP             GTP  P P  +            P  PG SR      P
Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAP 394

Query: 295 GSDGPMGGMG-----GMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRD 343
           G  G  G  G     G +     GS G     GLP        G   PPG P D
Sbjct: 395 GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLP--------GSPGPPGPPGD 440



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 80/292 (27%), Positives = 100/292 (34%), Gaps = 69/292 (23%)

Query: 106 PPND-GMPGGPIP------PGFF-QGPPGSQ--------PSPHAQPPPHNPSSMMGPHSQ 149
           PP D G PG P P      PG+  QG PG Q        P P  +  P    S+  P   
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656

Query: 150 PP--GGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPP 207
           PP   G PG              QG P + GS+ +   P   GP G  P   G G   PP
Sbjct: 657 PPGPPGPPG----------HPGPQGPPGIPGSLGKCGDPGLPGPDGE-PGIPGIGFPGPP 705

Query: 208 NSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT----YVGPPGGGGPPGTPIMP 262
              G    PG     G     P       +P     PG      V  PGG G PG     
Sbjct: 706 GPKGDQGFPGTKGSLGC----PGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG----- 756

Query: 263 SPADSTNSSDNIYTMINPVP-----PGGSRSNFPMG-------PGSDGPMG--------- 301
            P +  NS ++    +  +P     PG    + P G       PG  GP G         
Sbjct: 757 FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 302 ----GMGGMEPHH-MNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
               G+ G++      G  G     G+P    +   G +  PG P   GE+G
Sbjct: 817 QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG 868



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 77/258 (29%), Positives = 86/258 (33%), Gaps = 48/258 (18%)

Query: 95  AAAPSPVLGNIPPN------DGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHS 148
           AAAP+   G +  +      DG  G     GF  GPPGS      Q     P  + GP  
Sbjct: 22  AAAPAASKGCVCKDKGQCFCDGAKGEKGEKGF-PGPPGSP----GQKGFTGPEGLPGP-- 74

Query: 149 QPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMR 204
           Q P G PG  P L  S       G P   GS      P   GP G    PG         
Sbjct: 75  QGPKGFPGL-PGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133

Query: 205 PP--PNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP 262
            P  P +LG   PGI    G       P     I   +       G PG  G PG P  P
Sbjct: 134 FPGLPGTLG--YPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191

Query: 263 SPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDG 322
            P               P PPG     FP   G  GP G MG      + G  G   + G
Sbjct: 192 GPVGP------------PGPPGFF--GFPGAMGPRGPKGHMG----ERVIGHKGERGVKG 233

Query: 323 LPKNSPNNISGISNPPGT 340
           L        +G   PPGT
Sbjct: 234 L--------TGPPGPPGT 243



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 80/261 (30%), Positives = 90/261 (34%), Gaps = 57/261 (21%)

Query: 100  PVLGNIPP---NDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPG 156
            P L  IP    N GMPG     G   G PG    P   P  H      G     PG   G
Sbjct: 1008 PGLRGIPGSMGNMGMPGSKGKRGTL-GFPGRAGRP-GLPGIHGLQGDKGE----PGYSEG 1061

Query: 157  TQPLLPNSMDPTRQQGHP-NMG--GSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPA 213
            T+P  P    PT   G P +MG  G M +  PP  +GP GP            P S  P 
Sbjct: 1062 TRPGPPG---PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP---------EGAPGS--PG 1107

Query: 214  MPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP-SPADSTNSSD 272
             PG+      G+P P+ +               +GPPG  GPPG P  P SP       D
Sbjct: 1108 SPGL-----PGKPGPHGD------LGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156

Query: 273  NIYTMINPVPPG--GSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP------ 324
                 I P P G  G        PG  G  G  G        G  G+    GLP      
Sbjct: 1157 QGRDGI-PGPAGEKGETGLLRAPPGPRGNPGAQGA------KGDRGAPGFPGLPGRKGAM 1209

Query: 325  ----KNSPNNISGISNPPGTP 341
                   P  I G   PPG P
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLP 1230



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 89/337 (26%), Positives = 109/337 (32%), Gaps = 85/337 (25%)

Query: 81  EHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGG---PIPPGFFQGPPGSQPSPHAQPPP 137
           E   E  A  D     AP P    +P   G PG    P PPGFF  P    P     P  
Sbjct: 162 EEDIELDAKGDPGLPGAPGPQ--GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRG---PKG 216

Query: 138 HNPSSMMGPHSQP-------PGGVPGTQPLLPNSMDP-TRQQGHPNMGGSMQRMNPPRGM 189
           H    ++G   +        P G PGT  +     D  T  +G     G+M    PP   
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP--- 273

Query: 190 GPMGPGPQNYGS--------GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSI---- 236
           GP G   ++YGS        G++  P   G P  PG + G    R +P     + I    
Sbjct: 274 GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPG-SEGVKGNRGFPGLMGEDGIKGQK 332

Query: 237 ----PYSSSSPGTYV---------------------GPPGGGGPPGTPIMPSP------- 264
               P     P  Y                      GP G  GPPG P  P         
Sbjct: 333 GDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRG 392

Query: 265 ---------ADSTNSSDNIYTMINPVPPGGSRS-NFPMGPGSDGPMGGM----GGMEPHH 310
                    +           M  P  PG + S   P  PG  GP G +    G    H 
Sbjct: 393 APGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHG 452

Query: 311 MNGSLGSGDIDGL--PKNSPNNISG----ISNPPGTP 341
           + G LGS  I G+  PK  P  +      I  PPG P
Sbjct: 453 LPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLP 489



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 26/159 (16%)

Query: 106  PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSM--------MGPHSQPPG--GVP 155
            P   G PG P  PG  +G PG Q  P  +    NP  +        +GP   PPG  G P
Sbjct: 1291 PGRLGAPGTPGLPGP-RGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKG-PPGVRGDP 1348

Query: 156  GTQPL--LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPA 213
            GT  +  LP S  P    G P M G      PP  +GP GP  +    G    P + GPA
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGK---PGKDGKPGTPGPA 1405

Query: 214  MPGINMGPGAGRPWPNPNSANSIP------YSSSSPGTY 246
                N G    +  P P  ++ +P        S SP T+
Sbjct: 1406 GEKGNKG---SKGEPGPAGSDGLPGLKGKRGDSGSPATW 1441


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1637

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 85/268 (31%), Positives = 100/268 (37%), Gaps = 51/268 (19%)

Query: 102 LGNIPPNDGMPGGPIPPGFF--------QGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGG 153
           L  IP   G+ G P P G          QGPPG   SP   P P  P+   G   Q   G
Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP-GSPGPAGPAGPPGYGPQGEPG 625

Query: 154 VPGTQPLLPNSMDPTRQQG-HPNMGGSMQRMNPPRGMGPMG-PGPQNYGSGMRPP--PNS 209
           + GTQ + P +  P  + G    +  S     PP   GP G PGPQ       PP  P S
Sbjct: 626 LQGTQGV-PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG------PPGIPGS 678

Query: 210 LG----PAMPGINMGPGA---GRPWP-NPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIM 261
           LG    P +PG +  PG    G P P  P      P +  S    +G PG  G PG P  
Sbjct: 679 LGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS----LGCPGKMGEPGLPGK 734

Query: 262 PSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDID 321
           P                 P   G      P GPG+ G  G  G    H   G +G   + 
Sbjct: 735 PGL---------------PGAKGEPAVAMPGGPGTPGFPGERGNSGEH---GEIGLPGLP 776

Query: 322 GLPKNSPN-NISGISNPPGTPRDDGELG 348
           GLP    N  + G    PG P   GE G
Sbjct: 777 GLPGTPGNEGLDGPRGDPGQPGPPGEQG 804



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 90/303 (29%), Positives = 109/303 (35%), Gaps = 76/303 (25%)

Query: 96   AAPSPVLGNIPPNDGMPGGPIPPGFFQ--------GPPGSQPSPHAQPPPHNPSSM---- 143
            A P    G+ P + G+PG P P G           GPPG +  P     P +P  M    
Sbjct: 1097 AGPEGAPGS-PGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155

Query: 144  -------MGPHSQ---------PPG--GVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNP 185
                    GP  +         PPG  G PG Q    +   P    G P + G    M  
Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP----GFPGLPGRKGAMGD 1211

Query: 186  PRGMGPMG----PGPQNYGSGMRP-PPNSLGPAMPGINMGPGAGRPWPNPNSANSI---- 236
                GP G    PGP      + P    + GP  PG    PGA  P P P  ++ I    
Sbjct: 1212 AGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGP--PGSRGSPGAPGP-PGPPGSHVIGIKG 1268

Query: 237  -------PYSSSSPGTY--VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--G 285
                   P     PGT   +GPPG  G PGTP +P P                  PG  G
Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGF---------PGVKG 1319

Query: 286  SRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 345
             + N P   GS GP G +G   P  + G  G+  I  LP        G   PPGTP + G
Sbjct: 1320 EKGN-PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP--------GSPGPPGTPGEPG 1370

Query: 346  ELG 348
              G
Sbjct: 1371 MQG 1373



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 76/267 (28%), Positives = 92/267 (34%), Gaps = 34/267 (12%)

Query: 106 PPNDGMPGGPIPPGFFQGPPG--SQPSPHAQPP-----PHNPSSMMGPHSQPPGGVPGTQ 158
           P N G+PG P  PG  QG PG   +     QP      P +P     P  +   G+PGT 
Sbjct: 516 PGNTGLPGFPGFPGA-QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP 574

Query: 159 PL--LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYGSGMRPPPNSLGPAMP 215
            +  LP         G     G       P   GP GP GP  YG     P     P + 
Sbjct: 575 GVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYG-----PQGE--PGLQ 627

Query: 216 GINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIY 275
           G    PGA  P         +  S+  PG    PPG   PPG P  P P        ++ 
Sbjct: 628 GTQGVPGAPGPPGEAGPRGELSVSTPVPG----PPG---PPGPPGHPGPQGPPGIPGSLG 680

Query: 276 TMINPVPPGGSRS------NFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDI---DGLPKN 326
              +P  PG           FP  PG  G  G  G        G +G   +    GLP  
Sbjct: 681 KCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA 740

Query: 327 SPNNISGISNPPGTPRDDGELGGNFLH 353
                  +   PGTP   GE G +  H
Sbjct: 741 KGEPAVAMPGGPGTPGFPGERGNSGEH 767



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 74/235 (31%), Positives = 88/235 (37%), Gaps = 47/235 (20%)

Query: 109  DGMPGGPIPPGFF-------QGPPGSQPSPHAQPPPHNPSSMM-------GPHSQP-PGG 153
            +G PG P  PG         +GPPGS+ SP A  PP  P S +       G    P P G
Sbjct: 1221 EGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG 1280

Query: 154  VPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGS--GMRPPPN--- 208
             PGT       M P  + G P   G    +  PRG     PG Q +    G +  P    
Sbjct: 1281 PPGTA----GDMGPPGRLGAPGTPG----LPGPRG----DPGFQGFPGVKGEKGNPGFLG 1328

Query: 209  SLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADST 268
            S+GP  P    GP   R  P      S+P S   PGT  G PG  G PG P  P      
Sbjct: 1329 SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT-PGEPGMQGEPGPPGPPG----- 1382

Query: 269  NSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGL 323
                     + P  P G +      PG+ GP G  G        G  GS  + GL
Sbjct: 1383 --------NLGPCGPRG-KPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGL 1428



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 84/301 (27%), Positives = 101/301 (33%), Gaps = 55/301 (18%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-- 150
           S   A SP    +P + G PG P    F +GPPG    P     P  P  + GP  +P  
Sbjct: 419 SPGCAGSP---GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGL 474

Query: 151 ----------PGGVPGTQPL-----LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-P 194
                     P G+PG   L     +P        +G P   G+      P   G  G P
Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534

Query: 195 GPQNYGSGMRPPPNSLG-PAMPGINMGPG-------------AGRPWPNPNSANS----- 235
           G +        P   +G P  PG+   PG              G P P    A S     
Sbjct: 535 GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 236 --IPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNF--- 290
              P    SPG+  GP G  GPPG    P        +  +     P    G R      
Sbjct: 595 QGPPGDPGSPGS-PGPAGPAGPPG--YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVS 651

Query: 291 ---PMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGIS--NPPGTPRDD 344
              P  PG  GP G  G   P  + GSLG     GLP  +    I GI    PPG   D 
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQ 711

Query: 345 G 345
           G
Sbjct: 712 G 712



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 82/314 (26%), Positives = 107/314 (34%), Gaps = 71/314 (22%)

Query: 100  PVLGNIPPNDGM------PGGPIPPGFFQGPPG----------SQPSPHAQPPPHNPSSM 143
            P L   P N+G+      PG P PPG  QGPPG            P  +           
Sbjct: 776  PGLPGTPGNEGLDGPRGDPGQPGPPGE-QGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834

Query: 144  MGPHSQPPGGVPGTQPL-LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSG 202
             GP   P  G+PG      P         GH    G + +   P   G +GP  ++   G
Sbjct: 835  TGPKGDP--GIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG 892

Query: 203  MRPPPNSLGPAMPGINMG-------------------PGA-----GRPWPNPNSANSIPY 238
            M   P ++GP  P  N G                   PGA      +  P P+  + +  
Sbjct: 893  MMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIG 952

Query: 239  SSSSPGT--YVGPPGGGGPPGTPIM---------PSPADSTNSSDNIYTMINPVPPG--- 284
                PG   + G PG  G  G P M         P PA       ++ +  NP  PG   
Sbjct: 953  DKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012

Query: 285  --GSRSNFPMGPGSDGPMGGMG--------GMEPHHMNGSLGSGDIDGLPKNSPNNISGI 334
              GS  N  M PGS G  G +G        G+   H  G  G     G  + +     G 
Sbjct: 1013 IPGSMGNMGM-PGSKGKRGTLGFPGRAGRPGLPGIH--GLQGDKGEPGYSEGTRPGPPGP 1069

Query: 335  SNPPGTPRDDGELG 348
            +  PG P D G+ G
Sbjct: 1070 TGDPGLPGDMGKKG 1083



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 83/294 (28%), Positives = 98/294 (33%), Gaps = 58/294 (19%)

Query: 91  DYSAAAAPSPVLGNIPPNDGMPGGPIPPGFF--QGPPGSQPSPHAQPPPHNPSSMMGPH- 147
           D    A   P L   P   G+PG P  PG     GPPG    P A   P  P   MG   
Sbjct: 164 DIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM-GPRGPKGHMGERV 222

Query: 148 -----------SQPPGGVPGTQPL-LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPG 195
                         P G PGT  + L    + T  +G     G+M    PP   GP G  
Sbjct: 223 IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP---GPSGLP 279

Query: 196 PQNYGS--------GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTY 246
            ++YGS        G++  P   G P  PG + G    R +P     + I          
Sbjct: 280 GESYGSEKGAPGDPGLQGKPGKDGVPGFPG-SEGVKGNRGFPGLMGEDGIKGQKGD---- 334

Query: 247 VGPPGGGGP------------PGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP 294
           +GPPG  GP             GTP  P P  +            P  PG SR      P
Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAP 394

Query: 295 GSDGPMGGMG-----GMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRD 343
           G  G  G  G     G +     GS G     GLP        G   PPG P D
Sbjct: 395 GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLP--------GSPGPPGPPGD 440



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 80/292 (27%), Positives = 100/292 (34%), Gaps = 69/292 (23%)

Query: 106 PPND-GMPGGPIP------PGFF-QGPPGSQ--------PSPHAQPPPHNPSSMMGPHSQ 149
           PP D G PG P P      PG+  QG PG Q        P P  +  P    S+  P   
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656

Query: 150 PP--GGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPP 207
           PP   G PG              QG P + GS+ +   P   GP G  P   G G   PP
Sbjct: 657 PPGPPGPPG----------HPGPQGPPGIPGSLGKCGDPGLPGPDGE-PGIPGIGFPGPP 705

Query: 208 NSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT----YVGPPGGGGPPGTPIMP 262
              G    PG     G     P       +P     PG      V  PGG G PG     
Sbjct: 706 GPKGDQGFPGTKGSLGC----PGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG----- 756

Query: 263 SPADSTNSSDNIYTMINPVP-----PGGSRSNFPMG-------PGSDGPMG--------- 301
            P +  NS ++    +  +P     PG    + P G       PG  GP G         
Sbjct: 757 FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 302 ----GMGGMEPHH-MNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 348
               G+ G++      G  G     G+P    +   G +  PG P   GE+G
Sbjct: 817 QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG 868



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 77/258 (29%), Positives = 86/258 (33%), Gaps = 48/258 (18%)

Query: 95  AAAPSPVLGNIPPN------DGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHS 148
           AAAP+   G +  +      DG  G     GF  GPPGS      Q     P  + GP  
Sbjct: 22  AAAPAASKGCVCKDKGQCFCDGAKGEKGEKGF-PGPPGSP----GQKGFTGPEGLPGP-- 74

Query: 149 QPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMR 204
           Q P G PG  P L  S       G P   GS      P   GP G    PG         
Sbjct: 75  QGPKGFPGL-PGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133

Query: 205 PP--PNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP 262
            P  P +LG   PGI    G       P     I   +       G PG  G PG P  P
Sbjct: 134 FPGLPGTLG--YPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191

Query: 263 SPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDG 322
            P               P PPG     FP   G  GP G MG      + G  G   + G
Sbjct: 192 GPVGP------------PGPPGFF--GFPGAMGPRGPKGHMG----ERVIGHKGERGVKG 233

Query: 323 LPKNSPNNISGISNPPGT 340
           L        +G   PPGT
Sbjct: 234 L--------TGPPGPPGT 243



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 80/261 (30%), Positives = 90/261 (34%), Gaps = 57/261 (21%)

Query: 100  PVLGNIPP---NDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPG 156
            P L  IP    N GMPG     G   G PG    P   P  H      G     PG   G
Sbjct: 1008 PGLRGIPGSMGNMGMPGSKGKRGTL-GFPGRAGRP-GLPGIHGLQGDKGE----PGYSEG 1061

Query: 157  TQPLLPNSMDPTRQQGHP-NMG--GSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPA 213
            T+P  P    PT   G P +MG  G M +  PP  +GP GP            P S  P 
Sbjct: 1062 TRPGPPG---PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP---------EGAPGS--PG 1107

Query: 214  MPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP-SPADSTNSSD 272
             PG+      G+P P+ +               +GPPG  GPPG P  P SP       D
Sbjct: 1108 SPGL-----PGKPGPHGD------LGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156

Query: 273  NIYTMINPVPPG--GSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP------ 324
                 I P P G  G        PG  G  G  G        G  G+    GLP      
Sbjct: 1157 QGRDGI-PGPAGEKGETGLLRAPPGPRGNPGAQGA------KGDRGAPGFPGLPGRKGAM 1209

Query: 325  ----KNSPNNISGISNPPGTP 341
                   P  I G   PPG P
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLP 1230



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 89/337 (26%), Positives = 109/337 (32%), Gaps = 85/337 (25%)

Query: 81  EHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGG---PIPPGFFQGPPGSQPSPHAQPPP 137
           E   E  A  D     AP P    +P   G PG    P PPGFF  P    P     P  
Sbjct: 162 EEDIELDAKGDPGLPGAPGPQ--GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRG---PKG 216

Query: 138 HNPSSMMGPHSQP-------PGGVPGTQPLLPNSMDP-TRQQGHPNMGGSMQRMNPPRGM 189
           H    ++G   +        P G PGT  +     D  T  +G     G+M    PP   
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP--- 273

Query: 190 GPMGPGPQNYGS--------GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSI---- 236
           GP G   ++YGS        G++  P   G P  PG + G    R +P     + I    
Sbjct: 274 GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPG-SEGVKGNRGFPGLMGEDGIKGQK 332

Query: 237 ----PYSSSSPGTYV---------------------GPPGGGGPPGTPIMPSP------- 264
               P     P  Y                      GP G  GPPG P  P         
Sbjct: 333 GDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRG 392

Query: 265 ---------ADSTNSSDNIYTMINPVPPGGSRS-NFPMGPGSDGPMGGM----GGMEPHH 310
                    +           M  P  PG + S   P  PG  GP G +    G    H 
Sbjct: 393 APGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHG 452

Query: 311 MNGSLGSGDIDGL--PKNSPNNISG----ISNPPGTP 341
           + G LGS  I G+  PK  P  +      I  PPG P
Sbjct: 453 LPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLP 489



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 26/159 (16%)

Query: 106  PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSM--------MGPHSQPPG--GVP 155
            P   G PG P  PG  +G PG Q  P  +    NP  +        +GP   PPG  G P
Sbjct: 1291 PGRLGAPGTPGLPGP-RGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKG-PPGVRGDP 1348

Query: 156  GTQPL--LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPA 213
            GT  +  LP S  P    G P M G      PP  +GP GP  +    G    P + GPA
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGK---PGKDGKPGTPGPA 1405

Query: 214  MPGINMGPGAGRPWPNPNSANSIP------YSSSSPGTY 246
                N G    +  P P  ++ +P        S SP T+
Sbjct: 1406 GEKGNKG---SKGEPGPAGSDGLPGLKGKRGDSGSPATW 1441


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.136    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,813,887
Number of Sequences: 37866
Number of extensions: 2062546
Number of successful extensions: 23306
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 322
Number of HSP's successfully gapped in prelim test: 1460
Number of HSP's that attempted gapping in prelim test: 8699
Number of HSP's gapped (non-prelim): 6361
length of query: 368
length of database: 18,247,518
effective HSP length: 104
effective length of query: 264
effective length of database: 14,309,454
effective search space: 3777695856
effective search space used: 3777695856
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.