Guide to the Human Genome
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Search of human proteins with 21040362

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21040362 beta-site APP-cleaving enzyme 2 isoform B
preproprotein [Homo sapiens]
         (396 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprot...   797   0.0  
gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprot...   761   0.0  
gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprot...   655   0.0  
gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprote...   374   e-104
gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprot...   326   2e-89
gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprot...   306   2e-83
gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprot...   189   5e-48
gi|4505757 progastricsin (pepsinogen C) [Homo sapiens]                119   6e-27
gi|4503143 cathepsin D preproprotein [Homo sapiens]                    96   4e-20
gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens]          96   6e-20
gi|119372302 pepsinogen 4, group I [Homo sapiens]                      94   2e-19
gi|119372298 pepsinogen 3, group I [Homo sapiens]                      94   2e-19
gi|23943854 pepsinogen 5, group I [Homo sapiens]                       94   2e-19
gi|4506475 renin preproprotein [Homo sapiens]                          92   6e-19
gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens]         79   5e-15
gi|4758754 napsin A preproprotein [Homo sapiens]                       77   3e-14
gi|39995080 hypothetical protein LOC79567 [Homo sapiens]               33   0.45 
gi|197927448 WD repeat domain 6 protein [Homo sapiens]                 33   0.45 
gi|38683860 insulin receptor substrate 2 [Homo sapiens]                33   0.59 
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       33   0.59 
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       33   0.59 
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]           32   0.77 
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]           32   0.77 
gi|239753114 PREDICTED: hypothetical protein [Homo sapiens]            32   1.0  
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     32   1.0  
gi|124378039 SEC16 homolog A [Homo sapiens]                            31   1.7  
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             31   1.7  
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    30   3.8  
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    30   3.8  
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    30   3.8  

>gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprotein
           [Homo sapiens]
          Length = 396

 Score =  797 bits (2058), Expect = 0.0
 Identities = 396/396 (100%), Positives = 396/396 (100%)

Query: 1   MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60
           MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL
Sbjct: 1   MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60

Query: 61  ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120
           ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG
Sbjct: 61  ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120

Query: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180
           TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI
Sbjct: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180

Query: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240
           FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA
Sbjct: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240

Query: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300
           GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA
Sbjct: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300

Query: 301 IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI 360
           IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI
Sbjct: 301 IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI 360

Query: 361 YLRDENSSRSFRITILPQKLQVLQCLKFPGLSQQRM 396
           YLRDENSSRSFRITILPQKLQVLQCLKFPGLSQQRM
Sbjct: 361 YLRDENSSRSFRITILPQKLQVLQCLKFPGLSQQRM 396


>gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprotein
           [Homo sapiens]
          Length = 518

 Score =  761 bits (1966), Expect = 0.0
 Identities = 378/378 (100%), Positives = 378/378 (100%)

Query: 1   MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60
           MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL
Sbjct: 1   MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60

Query: 61  ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120
           ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG
Sbjct: 61  ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120

Query: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180
           TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI
Sbjct: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180

Query: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240
           FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA
Sbjct: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240

Query: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300
           GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA
Sbjct: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300

Query: 301 IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI 360
           IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI
Sbjct: 301 IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI 360

Query: 361 YLRDENSSRSFRITILPQ 378
           YLRDENSSRSFRITILPQ
Sbjct: 361 YLRDENSSRSFRITILPQ 378


>gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprotein
           [Homo sapiens]
          Length = 468

 Score =  655 bits (1691), Expect = 0.0
 Identities = 328/329 (99%), Positives = 329/329 (100%)

Query: 1   MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60
           MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL
Sbjct: 1   MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60

Query: 61  ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120
           ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG
Sbjct: 61  ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120

Query: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180
           TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI
Sbjct: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180

Query: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240
           FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA
Sbjct: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240

Query: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300
           GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA
Sbjct: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300

Query: 301 IVDSGTTLLRLPQKVFDAVVEAVARASLI 329
           IVDSGTTLLRLPQKVFDAVVEAVARASL+
Sbjct: 301 IVDSGTTLLRLPQKVFDAVVEAVARASLL 329


>gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprotein
           [Homo sapiens]
          Length = 501

 Score =  374 bits (960), Expect = e-104
 Identities = 176/312 (56%), Positives = 227/312 (72%), Gaps = 3/312 (0%)

Query: 71  PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
           P    +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV   PH ++  Y+
Sbjct: 54  PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113

Query: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPG 190
             + SSTYR     V V YTQG W G +G DLV+IP G N +   NIA I ES+ FF+ G
Sbjct: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFING 173

Query: 191 IKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGS---GTNGG 247
             W GILGLAYA +A+P  SLE FFDSLV Q ++PN+FS+Q+CGAG P+  S    + GG
Sbjct: 174 SNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGG 233

Query: 248 SLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTT 307
           S+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L +DC+EYN DK+IVDSGTT
Sbjct: 234 SMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTT 293

Query: 308 LLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENS 367
            LRLP+KVF+A V+++  AS   +F DGFW G QL CW    TPW+ FP IS+YL  E +
Sbjct: 294 NLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVT 353

Query: 368 SRSFRITILPQK 379
           ++SFRITILPQ+
Sbjct: 354 NQSFRITILPQQ 365


>gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprotein
           [Homo sapiens]
          Length = 476

 Score =  326 bits (836), Expect = 2e-89
 Identities = 160/312 (51%), Positives = 207/312 (66%), Gaps = 28/312 (8%)

Query: 71  PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
           P    +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV   PH ++  Y+
Sbjct: 54  PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113

Query: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPG 190
             + SSTYR     V V YTQG W G +G DLV+IP G N +   NIA I ES+ FF+ G
Sbjct: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFING 173

Query: 191 IKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGS---GTNGG 247
             W GILGLAYA +A+                         +CGAG P+  S    + GG
Sbjct: 174 SNWEGILGLAYAEIAR-------------------------LCGAGFPLNQSEVLASVGG 208

Query: 248 SLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTT 307
           S+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L +DC+EYN DK+IVDSGTT
Sbjct: 209 SMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTT 268

Query: 308 LLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENS 367
            LRLP+KVF+A V+++  AS   +F DGFW G QL CW    TPW+ FP IS+YL  E +
Sbjct: 269 NLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVT 328

Query: 368 SRSFRITILPQK 379
           ++SFRITILPQ+
Sbjct: 329 NQSFRITILPQQ 340


>gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprotein
           [Homo sapiens]
          Length = 457

 Score =  306 bits (784), Expect = 2e-83
 Identities = 152/312 (48%), Positives = 197/312 (63%), Gaps = 47/312 (15%)

Query: 71  PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
           P    +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV   PH ++  Y+
Sbjct: 54  PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113

Query: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPG 190
             + SSTYR     V V YTQG W G +G DL                            
Sbjct: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDL---------------------------- 145

Query: 191 IKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGS---GTNGG 247
                           P  SLE FFDSLV Q ++PN+FS+Q+CGAG P+  S    + GG
Sbjct: 146 ----------------PDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGG 189

Query: 248 SLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTT 307
           S+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L +DC+EYN DK+IVDSGTT
Sbjct: 190 SMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTT 249

Query: 308 LLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENS 367
            LRLP+KVF+A V+++  AS   +F DGFW G QL CW    TPW+ FP IS+YL  E +
Sbjct: 250 NLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVT 309

Query: 368 SRSFRITILPQK 379
           ++SFRITILPQ+
Sbjct: 310 NQSFRITILPQQ 321


>gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprotein
           [Homo sapiens]
          Length = 432

 Score =  189 bits (479), Expect = 5e-48
 Identities = 85/151 (56%), Positives = 114/151 (75%), Gaps = 3/151 (1%)

Query: 232 MCGAGLPVAGS---GTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSL 288
           +CGAG P+  S    + GGS+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L
Sbjct: 146 LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDL 205

Query: 289 NLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNS 348
            +DC+EYN DK+IVDSGTT LRLP+KVF+A V+++  AS   +F DGFW G QL CW   
Sbjct: 206 KMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAG 265

Query: 349 ETPWSYFPKISIYLRDENSSRSFRITILPQK 379
            TPW+ FP IS+YL  E +++SFRITILPQ+
Sbjct: 266 TTPWNIFPVISLYLMGEVTNQSFRITILPQQ 296



 Score =  109 bits (273), Expect = 4e-24
 Identities = 51/93 (54%), Positives = 64/93 (68%)

Query: 71  PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
           P    +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV   PH ++  Y+
Sbjct: 54  PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113

Query: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLV 163
             + SSTYR     V V YTQG W G +G DL+
Sbjct: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLL 146


>gi|4505757 progastricsin (pepsinogen C) [Homo sapiens]
          Length = 388

 Score =  119 bits (297), Expect = 6e-27
 Identities = 84/240 (35%), Positives = 131/240 (54%), Gaps = 26/240 (10%)

Query: 92  YYLEMLIGTPPQKLQILVDTGSSNFAV--------AGTPHSYIDTYFDTERSSTYRSKGF 143
           Y+ E+ IGTPPQ   +L DTGSSN  V        A T HS     F+   SSTY + G 
Sbjct: 73  YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSR----FNPSESSTYSTNGQ 128

Query: 144 DVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYAT 203
             +++Y  GS TGF G D +T+      +    ++      NF     +++GI+GLAY  
Sbjct: 129 TFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYA--QFDGIMGLAYPA 186

Query: 204 LAKPSSSLETFFDSLVTQANIPN-VFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGD 262
           L+   ++  T    +V +  + + VFS+ +          G++GG++V GG++ SLY G 
Sbjct: 187 LSVDEAT--TAMQGMVQEGALTSPVFSVYLSNQ------QGSSGGAVVFGGVDSSLYTGQ 238

Query: 263 IWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEA 322
           I++ P+ +E Y+QI I +  IGGQ+    C E    +AIVD+GT+LL +PQ+   A+++A
Sbjct: 239 IYWAPVTQELYWQIGIEEFLIGGQASGW-CSE--GCQAIVDTGTSLLTVPQQYMSALLQA 295


>gi|4503143 cathepsin D preproprotein [Homo sapiens]
          Length = 412

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 79/254 (31%), Positives = 128/254 (50%), Gaps = 27/254 (10%)

Query: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTY------FDTERSSTYRSKGFDV 145
           YY E+ IGTPPQ   ++ DTGSSN  V       +D        +++++SSTY   G   
Sbjct: 79  YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSF 138

Query: 146 TVKYTQGSWTGFVGEDLVTIP--KGFNTSFL--VNIATIFESENFFLPGI-----KWNGI 196
            + Y  GS +G++ +D V++P     + S L  V +      E    PGI     K++GI
Sbjct: 139 DIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGI 198

Query: 197 LGLAYATLAKPSSSLETFFDSLVTQANIP-NVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
           LG+AY  ++   +++   FD+L+ Q  +  N+FS       L        GG L+LGG +
Sbjct: 199 LGMAYPRISV--NNVLPVFDNLMQQKLVDQNIFSFY-----LSRDPDAQPGGELMLGGTD 251

Query: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKV 315
              YKG + Y  +  + Y+Q+ + ++E+    L L C+E    +AIVD+GT+L+  P   
Sbjct: 252 SKYYKGSLSYLNVTRKAYWQVHLDQVEV-ASGLTL-CKE--GCEAIVDTGTSLMVGPVDE 307

Query: 316 FDAVVEAVARASLI 329
              + +A+    LI
Sbjct: 308 VRELQKAIGAVPLI 321


>gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens]
          Length = 396

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 69/246 (28%), Positives = 122/246 (49%), Gaps = 16/246 (6%)

Query: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAG----TPHSYIDTYFDTERSSTYRSKGFDVTV 147
           Y+  + IG+PPQ   ++ DTGSSN  V      +P     + F   +SSTY   G   ++
Sbjct: 78  YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137

Query: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKP 207
           +Y  GS +G +G D V++ +G          ++ E    F+   +++GILGL Y +LA  
Sbjct: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVDA-EFDGILGLGYPSLAV- 194

Query: 208 SSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTP 267
              +   FD+++ Q    N+  + M    +     G  G  L+ GG + S + G + + P
Sbjct: 195 -GGVTPVFDNMMAQ----NLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249

Query: 268 IKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARAS 327
           + ++ Y+QI +  +++GG    + C E    +AIVD+GT+L+  P      +  A+  A 
Sbjct: 250 VTKQAYWQIALDNIQVGGTV--MFCSE--GCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305

Query: 328 LIPEFS 333
           +  E++
Sbjct: 306 VDGEYA 311


>gi|119372302 pepsinogen 4, group I [Homo sapiens]
          Length = 388

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/227 (32%), Positives = 120/227 (52%), Gaps = 22/227 (9%)

Query: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYI----DTYFDTERSSTYRSKGFDVTV 147
           Y+  + IGTP Q   ++ DTGSSN  V     S +       F+ E SSTY+S    V++
Sbjct: 76  YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135

Query: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESE-NFFLPGIKWNGILGLAYATLAK 206
            Y  GS TG +G D V +    +T+ +  ++   E+E   FL    ++GILGLAY +++ 
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLS---ETEPGSFLYYAPFDGILGLAYPSIS- 191

Query: 207 PSSSLETFFDSLVTQANIP-NVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWY 265
            SS     FD++  Q  +  ++FS+ +       +    +G  ++ GGI+ S Y G + +
Sbjct: 192 -SSGATPVFDNIWNQGLVSQDLFSVYL-------SADDQSGSVVIFGGIDSSYYTGSLNW 243

Query: 266 TPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLP 312
            P+  E Y+QI +  + + G++  + C E    +AIVD+GT+LL  P
Sbjct: 244 VPVTVEGYWQITVDSITMNGEA--IACAE--GCQAIVDTGTSLLTGP 286


>gi|119372298 pepsinogen 3, group I [Homo sapiens]
          Length = 388

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/227 (32%), Positives = 120/227 (52%), Gaps = 22/227 (9%)

Query: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYI----DTYFDTERSSTYRSKGFDVTV 147
           Y+  + IGTP Q   ++ DTGSSN  V     S +       F+ E SSTY+S    V++
Sbjct: 76  YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135

Query: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESE-NFFLPGIKWNGILGLAYATLAK 206
            Y  GS TG +G D V +    +T+ +  ++   E+E   FL    ++GILGLAY +++ 
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLS---ETEPGSFLYYAPFDGILGLAYPSIS- 191

Query: 207 PSSSLETFFDSLVTQANIP-NVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWY 265
            SS     FD++  Q  +  ++FS+ +       +    +G  ++ GGI+ S Y G + +
Sbjct: 192 -SSGATPVFDNIWNQGLVSQDLFSVYL-------SADDQSGSVVIFGGIDSSYYTGSLNW 243

Query: 266 TPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLP 312
            P+  E Y+QI +  + + G++  + C E    +AIVD+GT+LL  P
Sbjct: 244 VPVTVEGYWQITVDSITMNGEA--IACAE--GCQAIVDTGTSLLTGP 286


>gi|23943854 pepsinogen 5, group I [Homo sapiens]
          Length = 388

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/227 (32%), Positives = 120/227 (52%), Gaps = 22/227 (9%)

Query: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYI----DTYFDTERSSTYRSKGFDVTV 147
           Y+  + IGTP Q   ++ DTGSSN  V     S +       F+ E SSTY+S    V++
Sbjct: 76  YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135

Query: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESE-NFFLPGIKWNGILGLAYATLAK 206
            Y  GS TG +G D V +    +T+ +  ++   E+E   FL    ++GILGLAY +++ 
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLS---ETEPGSFLYYAPFDGILGLAYPSIS- 191

Query: 207 PSSSLETFFDSLVTQANIP-NVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWY 265
            SS     FD++  Q  +  ++FS+ +       +    +G  ++ GGI+ S Y G + +
Sbjct: 192 -SSGATPVFDNIWNQGLVSQDLFSVYL-------SADDKSGSVVIFGGIDSSYYTGSLNW 243

Query: 266 TPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLP 312
            P+  E Y+QI +  + + G++  + C E    +AIVD+GT+LL  P
Sbjct: 244 VPVTVEGYWQITVDSITMNGET--IACAE--GCQAIVDTGTSLLTGP 286


>gi|4506475 renin preproprotein [Homo sapiens]
          Length = 406

 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 64/239 (26%), Positives = 126/239 (52%), Gaps = 19/239 (7%)

Query: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDT------YFDTERSSTYRSKGFDV 145
           YY E+ IGTPPQ  +++ DTGSSN  V  +  S + T       FD   SS+Y+  G ++
Sbjct: 86  YYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTEL 145

Query: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
           T++Y+ G+ +GF+ +D++T+  G   + +    T   +  F L   +++G++G+ +  + 
Sbjct: 146 TLRYSTGTVSGFLSQDIITV-GGITVTQMFGEVTEMPALPFML--AEFDGVVGMGF--IE 200

Query: 206 KPSSSLETFFDSLVTQANI-PNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIW 264
           +    +   FD++++Q  +  +VFS            S + GG +VLGG +P  Y+G+  
Sbjct: 201 QAIGRVTPIFDNIISQGVLKEDVFSFYY---NRDSENSQSLGGQIVLGGSDPQHYEGNFH 257

Query: 265 YTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAV 323
           Y  + +   +QI++  + +G  +L  +    +   A+VD+G + +       + ++EA+
Sbjct: 258 YINLIKTGVWQIQMKGVSVGSSTLLCE----DGCLALVDTGASYISGSTSSIEKLMEAL 312


>gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens]
          Length = 363

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 12/191 (6%)

Query: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAG----TPHSYIDTYFDTERSSTYRSKGFDVTV 147
           Y+  + IG+PPQ   ++ DTGSSN  V      +P     + F   +SSTY   G   ++
Sbjct: 78  YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137

Query: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKP 207
           +Y  GS +G +G D V++ +G          ++ E    F+   +++GILGL Y +LA  
Sbjct: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVDA-EFDGILGLGYPSLA-- 193

Query: 208 SSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTP 267
              +   FD+++ Q    N+  + M    +     G  G  L+ GG + S + G + + P
Sbjct: 194 VGGVTPVFDNMMAQ----NLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249

Query: 268 IKEEWYYQIEI 278
           + ++ Y+QI +
Sbjct: 250 VTKQAYWQIAL 260


>gi|4758754 napsin A preproprotein [Homo sapiens]
          Length = 420

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 71/246 (28%), Positives = 120/246 (48%), Gaps = 22/246 (8%)

Query: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAG------TPHSYIDTYFDTERSSTYRSKGFDV 145
           Y+ E+ +GTPPQ   +  DTGSSN  V        +   ++   FD + SS++++ G   
Sbjct: 78  YFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKF 137

Query: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
            ++Y  G   G + ED +TI  G   + ++    ++E    F     ++GILGL +  L+
Sbjct: 138 AIQYGTGRVDGILSEDKLTIG-GIKGASVIFGEALWEPSLVFAFA-HFDGILGLGFPILS 195

Query: 206 KPSSSLETFFDSLVTQANIPN-VFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIW 264
                +    D LV Q  +   VFS       L       +GG LVLGG +P+ Y   + 
Sbjct: 196 V--EGVRPPMDVLVEQGLLDKPVFSFY-----LNRDPEEPDGGELVLGGSDPAHYIPPLT 248

Query: 265 YTPIKEEWYYQIEILKLEIG-GQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAV 323
           + P+    Y+QI + ++++G G +L   C +  A  AI+D+GT+L+  P +   A+  A+
Sbjct: 249 FVPVTVPAYWQIHMERVKVGPGLTL---CAKGCA--AILDTGTSLITGPTEEIRALHAAI 303

Query: 324 ARASLI 329
               L+
Sbjct: 304 GGIPLL 309


>gi|39995080 hypothetical protein LOC79567 [Homo sapiens]
          Length = 1219

 Score = 33.1 bits (74), Expect = 0.45
 Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 11/81 (13%)

Query: 22  PELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHAD-GLALALEPALASPAGAANFLAM 80
           P  +PAP       + +T + ++PTP P TPA +H+D  LA+A++  + + AG +   ++
Sbjct: 736 PLTSPAPDP-----SESTVQSLSPTPSPPTPAPQHSDLCLAMAVQTPVPTAAGGSGDRSL 790

Query: 81  VDNLQG-----DSGRGYYLEM 96
            + L       D  RG + E+
Sbjct: 791 EEALGALMAALDDYRGQFPEL 811


>gi|197927448 WD repeat domain 6 protein [Homo sapiens]
          Length = 1151

 Score = 33.1 bits (74), Expect = 0.45
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 17/102 (16%)

Query: 225 PNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE-----PSLY----------KGDIWYTPIK 269
           P V      GAG PV GSG++GG     G+      PSL+           G   YT  +
Sbjct: 558 PGVGGKARAGAGAPVVGSGSSGGGNAFTGLGPVSTLPSLHGKQGVTSVTCHGGYVYTTGR 617

Query: 270 EEWYYQIEILKLEIGGQSLNLDCREYN--ADKAIVDSGTTLL 309
           +  YYQ+ +   ++        CR  N  A   IV  G+ ++
Sbjct: 618 DGAYYQLFVRDGQLQPVLRQKSCRGMNWLAGLRIVPDGSMVI 659


>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
          Length = 1338

 Score = 32.7 bits (73), Expect = 0.59
 Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 12/89 (13%)

Query: 21   APELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGLALALEPALASPAGAANFLAM 80
            +PE +     LP R +A+ +  + P P P  P E +   L  A   A A   GAA+    
Sbjct: 1007 SPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYR--LPPASAVATAQGPGAAS---- 1060

Query: 81   VDNLQGDSG-RGYYLEMLIG---TPPQKL 105
              +L  D+G  G Y EM  G   TPPQ +
Sbjct: 1061 --SLSSDTGDNGDYTEMAFGVAATPPQPI 1087


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 32.7 bits (73), Expect = 0.59
 Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 46 TPGPGTPAERHADGLALALEPALASP--AGAANFLAMVDN 83
          TPGPGT     + G+A A  PA  SP  +G   F + + N
Sbjct: 43 TPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSN 82


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 32.7 bits (73), Expect = 0.59
 Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 46 TPGPGTPAERHADGLALALEPALASP--AGAANFLAMVDN 83
          TPGPGT     + G+A A  PA  SP  +G   F + + N
Sbjct: 43 TPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSN 82


>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
          Length = 4302

 Score = 32.3 bits (72), Expect = 0.77
 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 7/84 (8%)

Query: 117  AVAGTPHSYIDTY-FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLV 175
            A A  P  Y  T+ F TE ++  R++G +VT  Y         G  LVT+    N S   
Sbjct: 1402 ACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDP------GSYLVTVTASNNISAAN 1455

Query: 176  NIATIFESENFFLPGIKWNGILGL 199
            + A +   E   +  IK NG LGL
Sbjct: 1456 DSALVEVQEPVLVTSIKVNGSLGL 1479


>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
          Length = 4303

 Score = 32.3 bits (72), Expect = 0.77
 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 7/84 (8%)

Query: 117  AVAGTPHSYIDTY-FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLV 175
            A A  P  Y  T+ F TE ++  R++G +VT  Y         G  LVT+    N S   
Sbjct: 1402 ACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDP------GSYLVTVTASNNISAAN 1455

Query: 176  NIATIFESENFFLPGIKWNGILGL 199
            + A +   E   +  IK NG LGL
Sbjct: 1456 DSALVEVQEPVLVTSIKVNGSLGL 1479


>gi|239753114 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 322

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 5/45 (11%)

Query: 11  PLLAQWLLRAAPELA-----PAPFTLPLRVAAATNRVVAPTPGPG 50
           PL+A    ++AP L      PAP  L LR   A+  + AP+PG G
Sbjct: 204 PLIAPGAHQSAPPLPVLGRLPAPLPLQLRAGGASTGLAAPSPGRG 248


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 24/60 (40%), Positives = 26/60 (43%), Gaps = 9/60 (15%)

Query: 21  APELAPAPFTLPLRVAAATNRVVAPTPGPGTPAER-------HADGLALALEPALASPAG 73
           AP  A AP   P   AAA      P+PGP  P  R        A   A A  PA+A PAG
Sbjct: 138 APVAAAAPARAPRAAAAAA--TAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAG 195


>gi|124378039 SEC16 homolog A [Homo sapiens]
          Length = 2357

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 3/71 (4%)

Query: 19   RAAPELAPAPFTLPLRVAAATNRVVAPTPG---PGTPAERHADGLALALEPALASPAGAA 75
            R+ P LAPA F  PL      + +  PTP    P  P     +G A A   A   PA   
Sbjct: 2204 RSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEP 2263

Query: 76   NFLAMVDNLQG 86
              L+   +L G
Sbjct: 2264 KVLSSAASLPG 2274


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 26/71 (36%), Positives = 34/71 (47%), Gaps = 3/71 (4%)

Query: 21  APELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHAD-GLALALEPALASPAG-AANFL 78
           APE    P T P     A   VV  TP P  PAE   D G   +L P ++ P G A + L
Sbjct: 209 APEDPSGPGTGPSGTCEAPVAVVTVTPAP-EPAENSQDLGSTSSLGPGISGPRGQAPDTL 267

Query: 79  AMVDNLQGDSG 89
           + +D++   SG
Sbjct: 268 SYLDSVSLMSG 278


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 25/60 (41%), Positives = 29/60 (48%), Gaps = 3/60 (5%)

Query: 17  LLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPG-TPAERHADGLALALEPALA-SPAGA 74
           +L  AP  APAP   P+    A   V+AP P P   PA   A   A A  PA A +PA A
Sbjct: 142 VLAPAPAPAPAPVAAPVAAPVAV-AVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 200


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 25/60 (41%), Positives = 29/60 (48%), Gaps = 3/60 (5%)

Query: 17  LLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPG-TPAERHADGLALALEPALA-SPAGA 74
           +L  AP  APAP   P+    A   V+AP P P   PA   A   A A  PA A +PA A
Sbjct: 142 VLAPAPAPAPAPVAAPVAAPVAV-AVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 200


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 25/60 (41%), Positives = 29/60 (48%), Gaps = 3/60 (5%)

Query: 17  LLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPG-TPAERHADGLALALEPALA-SPAGA 74
           +L  AP  APAP   P+    A   V+AP P P   PA   A   A A  PA A +PA A
Sbjct: 153 VLAPAPAPAPAPVAAPVAAPVAV-AVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 211


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,919,210
Number of Sequences: 37866
Number of extensions: 796853
Number of successful extensions: 2360
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 2276
Number of HSP's gapped (non-prelim): 74
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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