Guide to the Human Genome
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Name: PGA3 Sequence: fasta or formatted (388aa) NCBI GI: 119372298
Description:

pepsinogen 3, group I

Referenced in:

Aspartic Proteases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.2         20           1
 C cysteine            1.8          7           1
 D aspartate           5.7         22           2
 E glutamate           4.1         16           1
 F phenylalanine       4.4         17           1
 G glycine             9.3         36           2
 H histidine           0.5          2           1
 I isoleucine          7.0         27           1
 K lysine              2.3          9           2
 L leucine             9.0         35           4
 M methionine          1.8          7           1
 N asparagine          4.6         18           2
 P proline             5.4         21           2
 Q glutamine           4.4         17           1
 R arginine            2.1          8           2
 S serine             11.3         44           3
 T threonine           7.2         28           1
 V valine              7.5         29           2
 W tryptophan          1.8          7           1
 Y tyrosine            4.6         18           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   pepsinogen 3, group I 
PGA4                  0.997   pepsinogen 4, group I 
PGA5                  0.992   pepsinogen 5, group I 
CTSE                  0.500   cathepsin E isoform a preproprotein 
PGC                   0.478   progastricsin (pepsinogen C) 
CTSD                  0.403   cathepsin D preproprotein 
NAPSA                 0.343   napsin A preproprotein 
CTSE                  0.319   cathepsin E isoform b preproprotein 
REN                   0.307   renin preproprotein 
LOC649034             0.176   PREDICTED: similar to pepsinogen 3, group I 
BACE2                 0.098   beta-site APP-cleaving enzyme 2 isoform A preproprot...
BACE1                 0.094   beta-site APP-cleaving enzyme 1 isoform A preproprote...
BACE2                 0.093   beta-site APP-cleaving enzyme 2 isoform C preproprot...
BACE2                 0.091   beta-site APP-cleaving enzyme 2 isoform B preproprot...
BACE1                 0.084   beta-site APP-cleaving enzyme 1 isoform B preproprot...
BACE1                 0.062   beta-site APP-cleaving enzyme 1 isoform C preproprot...
BACE1                 0.054   beta-site APP-cleaving enzyme 1 isoform D preproprot...
SMCHD1                0.013   structural maintenance of chromosomes flexible hing...
IGSF22                0.012   immunoglobulin superfamily, member 22 
APEH                  0.009   N-acylaminoacyl-peptide hydrolase 
BRCA2                 0.009   breast cancer 2, early onset 
NUAK2                 0.007   NUAK family, SNF1-like kinase, 2 
LHX4                  0.007   LIM homeobox protein 4 
TRIM24                0.005   transcriptional intermediary factor 1 alpha isoform ...
TRIM24                0.005   transcriptional intermediary factor 1 alpha isoform ...
TANC2                 0.005   tetratricopeptide repeat, ankyrin repeat and coiled...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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