Guide to the Human Genome
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Name: NAPSA Sequence: fasta or formatted (420aa) NCBI GI: 4758754
Description:

napsin A preproprotein

Referenced in:

Aspartic Proteases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.4         31           2
 C cysteine            1.4          6           1
 D aspartate           4.5         19           1
 E glutamate           4.3         18           2
 F phenylalanine       5.7         24           2
 G glycine            11.2         47           2
 H histidine           2.1          9           2
 I isoleucine          5.7         24           2
 K lysine              2.6         11           1
 L leucine            12.6         53           5
 M methionine          1.0          4           1
 N asparagine          2.1          9           1
 P proline             9.8         41           3
 Q glutamine           2.9         12           1
 R arginine            5.2         22           2
 S serine              5.5         23           3
 T threonine           4.8         20           2
 V valine              7.1         30           1
 W tryptophan          1.9          8           1
 Y tyrosine            2.1          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   napsin A preproprotein 
CTSD                  0.429   cathepsin D preproprotein 
CTSE                  0.367   cathepsin E isoform a preproprotein 
REN                   0.325   renin preproprotein 
PGA5                  0.312   pepsinogen 5, group I 
PGA4                  0.310   pepsinogen 4, group I 
PGA3                  0.310   pepsinogen 3, group I 
PGC                   0.268   progastricsin (pepsinogen C) 
CTSE                  0.220   cathepsin E isoform b preproprotein 
BACE2                 0.063   beta-site APP-cleaving enzyme 2 isoform C preproprot...
BACE2                 0.062   beta-site APP-cleaving enzyme 2 isoform A preproprot...
BACE2                 0.062   beta-site APP-cleaving enzyme 2 isoform B preproprot...
LOC649034             0.050   PREDICTED: similar to pepsinogen 3, group I 
BACE1                 0.049   beta-site APP-cleaving enzyme 1 isoform A preproprote...
BACE1                 0.043   beta-site APP-cleaving enzyme 1 isoform B preproprot...
BACE1                 0.030   beta-site APP-cleaving enzyme 1 isoform C preproprot...
BACE1                 0.027   beta-site APP-cleaving enzyme 1 isoform D preproprot...
ARHGAP12              0.007   Rho GTPase activating protein 12 
IGFBP6                0.005   insulin-like growth factor binding protein 6 
LOC100292064          0.005   PREDICTED: hypothetical protein XP_002345331 
LOC100290378          0.005   PREDICTED: hypothetical protein XP_002347782 
LOC100287901          0.005   PREDICTED: hypothetical protein XP_002342210 
OXER1                 0.005   G-protein coupled receptor TG1019 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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