Guide to the Human Genome
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Name: REN Sequence: fasta or formatted (406aa) NCBI GI: 4506475
Description:

renin preproprotein

Referenced in:

Aspartic Proteases
Cardiovascular System
Kidney
Peptide-processing Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.2         17           1
 C cysteine            1.7          7           1
 D aspartate           4.9         20           1
 E glutamate           4.7         19           1
 F phenylalanine       5.4         22           1
 G glycine             9.9         40           2
 H histidine           1.5          6           1
 I isoleucine          5.9         24           2
 K lysine              4.7         19           2
 L leucine             9.1         37           5
 M methionine          3.2         13           1
 N asparagine          3.0         12           2
 P proline             4.4         18           3
 Q glutamine           3.2         13           1
 R arginine            4.7         19           2
 S serine              9.1         37           3
 T threonine           8.6         35           3
 V valine              5.9         24           2
 W tryptophan          1.7          7           1
 Y tyrosine            4.2         17           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   renin preproprotein 
CTSD                  0.376   cathepsin D preproprotein 
NAPSA                 0.339   napsin A preproprotein 
CTSE                  0.325   cathepsin E isoform a preproprotein 
PGA5                  0.293   pepsinogen 5, group I 
PGA4                  0.291   pepsinogen 4, group I 
PGA3                  0.291   pepsinogen 3, group I 
PGC                   0.260   progastricsin (pepsinogen C) 
CTSE                  0.188   cathepsin E isoform b preproprotein 
BACE2                 0.098   beta-site APP-cleaving enzyme 2 isoform A preproprot...
BACE2                 0.093   beta-site APP-cleaving enzyme 2 isoform C preproprot...
BACE2                 0.083   beta-site APP-cleaving enzyme 2 isoform B preproprot...
BACE1                 0.072   beta-site APP-cleaving enzyme 1 isoform A preproprote...
BACE1                 0.061   beta-site APP-cleaving enzyme 1 isoform B preproprot...
BACE1                 0.041   beta-site APP-cleaving enzyme 1 isoform C preproprot...
LOC649034             0.041   PREDICTED: similar to pepsinogen 3, group I 
BACE1                 0.027   beta-site APP-cleaving enzyme 1 isoform D preproprot...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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