Guide to the Human Genome
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Name: PGC Sequence: fasta or formatted (388aa) NCBI GI: 4505757
Description:

progastricsin (pepsinogen C)

Referenced in:

Aspartic Proteases
Stomach, Small Intestine, and Colon

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.9         23           2
 C cysteine            1.8          7           1
 D aspartate           3.1         12           1
 E glutamate           5.2         20           2
 F phenylalanine       5.4         21           2
 G glycine             9.8         38           2
 H histidine           0.5          2           1
 I isoleucine          3.9         15           2
 K lysine              2.3          9           2
 L leucine             9.5         37           2
 M methionine          2.3          9           1
 N asparagine          4.4         17           2
 P proline             4.9         19           2
 Q glutamine           7.0         27           2
 R arginine            1.5          6           1
 S serine             10.1         39           2
 T threonine           6.7         26           2
 V valine              8.0         31           3
 W tryptophan          1.8          7           1
 Y tyrosine            5.9         23           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   progastricsin (pepsinogen C) 
PGA4                  0.475   pepsinogen 4, group I 
PGA3                  0.475   pepsinogen 3, group I 
PGA5                  0.471   pepsinogen 5, group I 
CTSE                  0.428   cathepsin E isoform a preproprotein 
CTSD                  0.345   cathepsin D preproprotein 
NAPSA                 0.294   napsin A preproprotein 
CTSE                  0.291   cathepsin E isoform b preproprotein 
REN                   0.273   renin preproprotein 
BACE2                 0.128   beta-site APP-cleaving enzyme 2 isoform C preproprot...
BACE2                 0.123   beta-site APP-cleaving enzyme 2 isoform A preproprot...
BACE2                 0.123   beta-site APP-cleaving enzyme 2 isoform B preproprot...
BACE1                 0.085   beta-site APP-cleaving enzyme 1 isoform B preproprot...
BACE1                 0.085   beta-site APP-cleaving enzyme 1 isoform A preproprote...
LOC649034             0.078   PREDICTED: similar to pepsinogen 3, group I 
BACE1                 0.064   beta-site APP-cleaving enzyme 1 isoform C preproprot...
BACE1                 0.056   beta-site APP-cleaving enzyme 1 isoform D preproprot...
EYA4                  0.016   eyes absent 4 isoform d 
EYA4                  0.016   eyes absent 4 isoform b 
EYA4                  0.016   eyes absent 4 isoform a 
LRP2                  0.005   low density lipoprotein-related protein 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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