BACE1 12612

Name: BACE1	Sequence: fasta or formatted (432aa)		NCBI GI: 21040368
Description: beta-site APP-cleaving enzyme 1 isoform D preproprotein		Referenced in: Aspartic Proteases Additional Brain Proteins
Other entries for this name: alt prot [457aa] beta-site APP-cleaving enzyme 1 isoform C preproprotein alt prot [476aa] beta-site APP-cleaving enzyme 1 isoform B preproprotein alt prot [501aa] beta-site APP-cleaving enzyme 1 isoform A preproprotein
Composition: Amino acid Percentage Count Longest homopolymer A alanine 6.5 28 2 C cysteine 2.5 11 1 D aspartate 5.3 23 2 E glutamate 5.6 24 2 F phenylalanine 3.9 17 1 G glycine 9.0 39 2 H histidine 1.9 8 1 I isoleucine 5.1 22 2 K lysine 3.2 14 2 L leucine 10.0 43 3 M methionine 3.2 14 1 N asparagine 2.3 10 1 P proline 5.3 23 2 Q glutamine 4.6 20 2 R arginine 5.6 24 2 S serine 6.2 27 2 T threonine 5.8 25 2 V valine 7.4 32 2 W tryptophan 2.1 9 1 Y tyrosine 4.4 19 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 beta-site APP-cleaving enzyme 1 isoform D preproprot... BACE1 0.984 beta-site APP-cleaving enzyme 1 isoform C preproprot... BACE1 0.976 beta-site APP-cleaving enzyme 1 isoform B preproprot... BACE1 0.655 beta-site APP-cleaving enzyme 1 isoform A preproprote... BACE2 0.279 beta-site APP-cleaving enzyme 2 isoform A preproprot... BACE2 0.189 beta-site APP-cleaving enzyme 2 isoform B preproprot... BACE2 0.166 beta-site APP-cleaving enzyme 2 isoform C preproprot... PGC 0.050 progastricsin (pepsinogen C) CTSE 0.048 cathepsin E isoform a preproprotein PGA4 0.047 pepsinogen 4, group I PGA3 0.047 pepsinogen 3, group I PGA5 0.047 pepsinogen 5, group I CTSD 0.033 cathepsin D preproprotein CTSE 0.031 cathepsin E isoform b preproprotein NAPSA 0.027 napsin A preproprotein REN 0.025 renin preproprotein ZNF385A 0.013 zinc finger protein 385A isoform b NSL1 0.009 NSL1, MIND kinetochore complex component isoform 2 ... NSL1 0.009 NSL1, MIND kinetochore complex component isoform 1 ... RPRD2 0.007 Regulation of nuclear pre-mRNA domain containing 2 ... HS3ST3A1 0.007 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3... ZNF385A 0.006 zinc finger protein 385A isoform a ZNF385A 0.006 zinc finger protein 385A isoform c C2orf3 0.006 hypothetical protein LOC6936 FAM134B 0.006 hypothetical protein LOC54463 isoform 1 ASB15 0.005 ankyrin repeat and SOCS box-containing 15 FLJ23834 0.005 hypothetical protein LOC222256 KCNJ15 0.005 potassium inwardly-rectifying channel J15 KCNJ15 0.005 potassium inwardly-rectifying channel J15 KCNJ15 0.005 potassium inwardly-rectifying channel J15 Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.