Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help
Name: CTSD Sequence: fasta or formatted (412aa) NCBI GI: 4503143
Description:

cathepsin D preproprotein

Referenced in:

Aspartic Proteases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.8         28           2
 C cysteine            2.2          9           1
 D aspartate           5.1         21           1
 E glutamate           4.1         17           1
 F phenylalanine       3.4         14           1
 G glycine             9.5         39           2
 H histidine           1.5          6           2
 I isoleucine          5.6         23           1
 K lysine              5.6         23           1
 L leucine            10.0         41           2
 M methionine          2.4         10           1
 N asparagine          2.7         11           2
 P proline             6.3         26           3
 Q glutamine           4.1         17           2
 R arginine            2.9         12           2
 S serine              9.0         37           2
 T threonine           5.1         21           1
 V valine              8.3         34           2
 W tryptophan          1.0          4           1
 Y tyrosine            4.6         19           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cathepsin D preproprotein 
NAPSA                 0.447   napsin A preproprotein 
CTSE                  0.419   cathepsin E isoform a preproprotein 
PGA4                  0.380   pepsinogen 4, group I 
PGA3                  0.380   pepsinogen 3, group I 
PGA5                  0.379   pepsinogen 5, group I 
REN                   0.375   renin preproprotein 
PGC                   0.327   progastricsin (pepsinogen C) 
CTSE                  0.235   cathepsin E isoform b preproprotein 
BACE2                 0.097   beta-site APP-cleaving enzyme 2 isoform A preproprot...
BACE2                 0.097   beta-site APP-cleaving enzyme 2 isoform C preproprot...
BACE1                 0.094   beta-site APP-cleaving enzyme 1 isoform A preproprote...
BACE2                 0.088   beta-site APP-cleaving enzyme 2 isoform B preproprot...
BACE1                 0.077   beta-site APP-cleaving enzyme 1 isoform B preproprot...
BACE1                 0.061   beta-site APP-cleaving enzyme 1 isoform C preproprot...
LOC649034             0.055   PREDICTED: similar to pepsinogen 3, group I 
BACE1                 0.036   beta-site APP-cleaving enzyme 1 isoform D preproprot...
TMEM30B               0.009   transmembrane protein 30B 
MOSPD3                0.005   motile sperm domain containing 3 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press