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Search of human proteins with 21040351
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
(246 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 512 e-145
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 502 e-142
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 465 e-131
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 456 e-128
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 456 e-128
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 311 4e-85
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 309 2e-84
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 268 2e-72
gi|17986001 major histocompatibility complex, class I, B precurs... 158 5e-39
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 150 1e-36
gi|149158702 major histocompatibility complex, class I, F isofor... 149 2e-36
gi|149158698 major histocompatibility complex, class I, F isofor... 149 2e-36
gi|52630342 major histocompatibility complex, class I, C precurs... 148 5e-36
gi|24797067 major histocompatibility complex, class I, A precurs... 145 3e-35
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 142 3e-34
gi|4504415 major histocompatibility complex, class I, G precurso... 142 3e-34
gi|4504417 major histocompatibility complex, class I-related [Ho... 142 3e-34
gi|62912479 major histocompatibility complex, class I, E precurs... 138 5e-33
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 103 2e-22
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 100 2e-21
gi|21040357 hemochromatosis protein isoform 11 precursor [Homo s... 99 3e-21
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 99 4e-21
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 99 4e-21
gi|239740918 PREDICTED: similar to major histocompatibility comp... 83 3e-16
gi|239740920 PREDICTED: similar to major histocompatibility comp... 82 3e-16
gi|169168591 PREDICTED: similar to major histocompatibility comp... 79 4e-15
gi|24797076 major histocompatibility complex, class II, DP beta ... 78 8e-15
gi|150418002 major histocompatibility complex, class II, DQ beta... 75 5e-14
gi|52630344 major histocompatibility complex, class II, DR beta ... 75 5e-14
gi|239758090 PREDICTED: major histocompatibility complex, class ... 75 5e-14
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 512 bits (1318), Expect = e-145
Identities = 246/246 (100%), Positives = 246/246 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
Query: 61 CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT 120
CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT
Sbjct: 61 CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT 120
Query: 121 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 180
LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC
Sbjct: 121 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 180
Query: 181 QVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 240
QVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY
Sbjct: 181 QVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 240
Query: 241 VLAERE 246
VLAERE
Sbjct: 241 VLAERE 246
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 502 bits (1293), Expect = e-142
Identities = 246/260 (94%), Positives = 246/260 (94%), Gaps = 14/260 (5%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
Query: 61 CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV-- 118
CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV
Sbjct: 61 CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPP 120
Query: 119 ------------TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 166
TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI
Sbjct: 121 LVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 180
Query: 167 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 226
TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII
Sbjct: 181 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 240
Query: 227 LRKRQGSRGAMGHYVLAERE 246
LRKRQGSRGAMGHYVLAERE
Sbjct: 241 LRKRQGSRGAMGHYVLAERE 260
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 465 bits (1197), Expect = e-131
Identities = 220/221 (99%), Positives = 221/221 (100%)
Query: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 114 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 173
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMD 145
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMD
Sbjct: 174 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMD 233
Query: 146 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 205
AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI
Sbjct: 234 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 293
Query: 206 GVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 246
GVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 294 GVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334
Score = 59.3 bits (142), Expect = 3e-09
Identities = 31/52 (59%), Positives = 37/52 (71%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGY 52
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGY 52
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 456 bits (1172), Expect = e-128
Identities = 220/235 (93%), Positives = 221/235 (94%), Gaps = 14/235 (5%)
Query: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 91 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 150
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV--------------TTLRCRALNYYPQ 131
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV TTLRCRALNYYPQ
Sbjct: 151 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 210
Query: 132 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 191
NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL
Sbjct: 211 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 270
Query: 192 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 246
IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 271 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325
Score = 50.1 bits (118), Expect = 2e-06
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 456 bits (1172), Expect = e-128
Identities = 220/235 (93%), Positives = 221/235 (94%), Gaps = 14/235 (5%)
Query: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 114 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 173
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV--------------TTLRCRALNYYPQ 131
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV TTLRCRALNYYPQ
Sbjct: 174 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 233
Query: 132 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 191
NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL
Sbjct: 234 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 293
Query: 192 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 246
IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 294 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348
Score = 59.3 bits (142), Expect = 3e-09
Identities = 31/52 (59%), Positives = 37/52 (71%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGY 52
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGY 52
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 311 bits (796), Expect = 4e-85
Identities = 168/247 (68%), Positives = 184/247 (74%), Gaps = 6/247 (2%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY F
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 CPDTLDWRAAEPRA-WPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVT 119
+ R EPR W + + ++ Q+ + ++E +VT
Sbjct: 61 YDH--ESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN---HSKVT 115
Query: 120 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 179
TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT
Sbjct: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
Query: 180 CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGH 239
CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGH
Sbjct: 176 CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGH 235
Query: 240 YVLAERE 246
YVLAERE
Sbjct: 236 YVLAERE 242
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 309 bits (791), Expect = 2e-84
Identities = 170/259 (65%), Positives = 189/259 (72%), Gaps = 16/259 (6%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY F
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 CPDTLDWRAAEPRA-WPTKLEWERHKIRARQNR------------AYLERDCPAQLQQLL 107
+ R EPR W + + ++ Q+ +E +++ L+
Sbjct: 61 YDH--ESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVPPLV 118
Query: 108 ELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWIT 167
++ V VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWIT
Sbjct: 119 KVTHHVTSS-VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWIT 177
Query: 168 LAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIIL 227
LAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIIL
Sbjct: 178 LAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIIL 237
Query: 228 RKRQGSRGAMGHYVLAERE 246
RKRQGSRGAMGHYVLAERE
Sbjct: 238 RKRQGSRGAMGHYVLAERE 256
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 268 bits (686), Expect = 2e-72
Identities = 129/129 (100%), Positives = 129/129 (100%)
Query: 118 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 177
VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR
Sbjct: 40 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 99
Query: 178 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 237
YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM
Sbjct: 100 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 159
Query: 238 GHYVLAERE 246
GHYVLAERE
Sbjct: 160 GHYVLAERE 168
Score = 50.1 bits (118), Expect = 2e-06
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 158 bits (399), Expect = 5e-39
Identities = 85/231 (36%), Positives = 130/231 (56%), Gaps = 19/231 (8%)
Query: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ + GC++ D G+ +Y YDG+D++ D W AA+ A T+ +WE +
Sbjct: 116 SHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR 175
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYP 130
A Q RAYLE +C L++ LE G+ L++ TLRC AL +YP
Sbjct: 176 -EAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYP 234
Query: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
IT+ W +D + ++ E + P GD T+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 235 AEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKP 293
Query: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 240
L + WEPS T+ ++G+++G+AV V++ ++ ++ +R+ S G G Y
Sbjct: 294 LTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY 344
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 150 bits (378), Expect = 1e-36
Identities = 85/228 (37%), Positives = 125/228 (54%), Gaps = 19/228 (8%)
Query: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ++ GC++ D G+ + YDG+D++ D W AA+ A TK + E
Sbjct: 129 SHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQITKRKREAAG 188
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVL---------------DQQVTTLRCRALNYYP 130
RQ R YLE C L++ LE G+ L ++ TLRC AL +YP
Sbjct: 189 AAERQ-RNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTLRCWALGFYP 247
Query: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
+ I++ W ++ + ++ E + P+GDGT+Q W L VP GEEQRYTC+V+H GL +P
Sbjct: 248 EEISLTWQREGEDQ-TQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGLQEP 306
Query: 191 LIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 238
L + WEP + L++G+I G+ + VV L G + I +KR G G G
Sbjct: 307 LTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV-IWRKKRSGREGREG 353
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 149 bits (377), Expect = 2e-36
Identities = 83/231 (35%), Positives = 127/231 (54%), Gaps = 19/231 (8%)
Query: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ + GC+M D GY ++ YDG+D++ D W AA+ A T+ +E +
Sbjct: 113 SHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE 172
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYP 130
A + R YLE +C L++ LE G+ L + TLRC AL +YP
Sbjct: 173 Y-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYP 231
Query: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QP
Sbjct: 232 AEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQP 290
Query: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 240
LI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 291 LILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 149 bits (377), Expect = 2e-36
Identities = 83/231 (35%), Positives = 127/231 (54%), Gaps = 19/231 (8%)
Query: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ + GC+M D GY ++ YDG+D++ D W AA+ A T+ +E +
Sbjct: 113 SHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE 172
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYP 130
A + R YLE +C L++ LE G+ L + TLRC AL +YP
Sbjct: 173 Y-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYP 231
Query: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QP
Sbjct: 232 AEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQP 290
Query: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 240
LI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 291 LILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 148 bits (373), Expect = 5e-36
Identities = 84/229 (36%), Positives = 125/229 (54%), Gaps = 19/229 (8%)
Query: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ + GC++ D GY + YDG+D++ D W AA+ A T+ + E +
Sbjct: 116 SHTLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAAR 175
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYP 130
A Q RAYLE C L++ LE G+ L + TLRC AL +YP
Sbjct: 176 A-AEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYP 234
Query: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
IT+ W +D + ++ E + P GDGT+Q W + VP G+EQRYTC ++H GL +P
Sbjct: 235 AEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEP 293
Query: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 238
L + WEPS T+ ++G+++G+AV VV+ +G + + R+ S G G
Sbjct: 294 LTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKG 342
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 145 bits (366), Expect = 3e-35
Identities = 82/234 (35%), Positives = 125/234 (53%), Gaps = 19/234 (8%)
Query: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHT+Q++ GC++ D GY + YDG+D++ D W AA+ A TK +WE
Sbjct: 116 SHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH 175
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYP 130
A Q RAYL+ C L++ LE G+ L + TLRC AL +YP
Sbjct: 176 -EAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYP 234
Query: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 235 AEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKP 293
Query: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLA 243
L + WE S T+ ++G+I+G+ + ++ ++ ++ +R+ S G Y A
Sbjct: 294 LTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQA 347
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 142 bits (358), Expect = 3e-34
Identities = 73/190 (38%), Positives = 110/190 (57%), Gaps = 23/190 (12%)
Query: 27 SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKI 86
SH LQ GCE++ + S+ +WKY YDG+D++EF + W +P A TK +WE +
Sbjct: 114 SHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPV 173
Query: 87 RARQNRAYLERDCPAQLQQLLELGRGVLDQQ------VTT---------LRCRALNYYPQ 131
++ +AYLE +CPA L++ L+ + +LD+Q VT+ L+C A ++YP
Sbjct: 174 YVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPG 233
Query: 132 NITMKWLKDKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLD 188
I + W + + EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+H L
Sbjct: 234 KIDVHWTRAGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLA 288
Query: 189 QPLIVIWEPS 198
QPL+V WE S
Sbjct: 289 QPLVVPWEAS 298
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 142 bits (357), Expect = 3e-34
Identities = 81/224 (36%), Positives = 124/224 (55%), Gaps = 19/224 (8%)
Query: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ ++GC++ D GY +Y YDG+D+L D W AA+ A +K + E
Sbjct: 116 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN 175
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQ------QVT---------TLRCRALNYYP 130
+ A Q RAYLE C L + LE G+ +L + VT TLRC AL +YP
Sbjct: 176 V-AEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYP 234
Query: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
I + W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 235 AEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEP 293
Query: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 233
L++ W+ S T+ ++G+++G+ V ++ + +L +++ S
Sbjct: 294 LMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 142 bits (357), Expect = 3e-34
Identities = 81/219 (36%), Positives = 120/219 (54%), Gaps = 18/219 (8%)
Query: 27 SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKI 86
SHT Q ++GCE+ ED ST G+ +Y YDGQD L F DTL W A + A K WE ++
Sbjct: 111 SHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQH 170
Query: 87 RARQNRAYLERDCPAQLQQLLELGRGVLDQQ---------------VTTLRCRALNYYPQ 131
+ +LE +C A L++ LE G+ L + VT L C+A +YP
Sbjct: 171 ELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPP 230
Query: 132 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 191
I M W+K+ + + +E + D+LP+GDGTYQ W ++ + P Y+C VEH G+ L
Sbjct: 231 EIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVL 289
Query: 192 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 230
V E S + LV+ +SG V V++L G+ ++ R+R
Sbjct: 290 QVPQE-SETIPLVMKAVSGSIVLVIVL-AGVGVLVWRRR 326
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 138 bits (347), Expect = 5e-33
Identities = 79/235 (33%), Positives = 122/235 (51%), Gaps = 19/235 (8%)
Query: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ + GCE+ D GY ++ YDG+D+L D W A + A ++ +
Sbjct: 113 SHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDA 171
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVL---------------DQQVTTLRCRALNYYP 130
A RAYLE C L + LE G+ L TLRC AL +YP
Sbjct: 172 SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYP 231
Query: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 232 AEITLTWQQDGEG-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEP 290
Query: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 244
+ + W+P+ T+ ++G+I+G+ + ++ ++ ++ +++ S G G Y AE
Sbjct: 291 VTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAE 345
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 103 bits (256), Expect = 2e-22
Identities = 66/221 (29%), Positives = 103/221 (46%), Gaps = 34/221 (15%)
Query: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRA-----AEPRAWPTKLEWE 82
H+LQ I CE+ EDNST + YDG+ L +T +W A+ A + +
Sbjct: 111 HSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLK 170
Query: 83 RHKIRARQNRAYLERDCPAQLQQLLELG--------------RGVLDQQVTTLRCRALNY 128
++ + + + DC +L++ L+ G R + T+ CRA +
Sbjct: 171 EDAMKTKTHYHAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGF 230
Query: 129 YPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLD 188
YP NIT+ W +D + + DVLP+G+GTYQ W+ + GEEQR+TC +EH G
Sbjct: 231 YPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNH 290
Query: 189 QPLIVIWEPSPSG----------TLVIGVISGIAVFVVILF 219
P PSG T + ++ A+FV+I+F
Sbjct: 291 ST-----HPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIF 326
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 99.8 bits (247), Expect = 2e-21
Identities = 61/197 (30%), Positives = 99/197 (50%), Gaps = 24/197 (12%)
Query: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQ----DHLEFCPDTLDWRA-AEPRAWPTKLEWE 82
H+LQ I CE+ ED+ST G + YDG+ +LE T+ + A+ A W+
Sbjct: 111 HSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWK 170
Query: 83 RHKIRARQNRAYLERDCPAQLQQLLELGRGV--------------LDQQVTTLRCRALNY 128
++ + + ++ DC +LQ+ L+ G + + + T+ CRA ++
Sbjct: 171 EDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSF 230
Query: 129 YPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLD 188
YP+NIT+ W +D + + DVLP+G+GTYQ W+ + GEEQR+TC +EH G
Sbjct: 231 YPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNH 290
Query: 189 QPLIVIWEPSPSGTLVI 205
P PSG ++
Sbjct: 291 GT-----HPVPSGKALV 302
>gi|21040357 hemochromatosis protein isoform 11 precursor [Homo
sapiens]
Length = 76
Score = 99.0 bits (245), Expect = 3e-21
Identities = 50/51 (98%), Positives = 51/51 (100%)
Query: 196 EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 246
+PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 26 QPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 76
Score = 52.0 bits (123), Expect = 5e-07
Identities = 26/26 (100%), Positives = 26/26 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQ 26
MGPRARPALLLLMLLQTAVLQGRLLQ
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQ 26
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 98.6 bits (244), Expect = 4e-21
Identities = 61/212 (28%), Positives = 101/212 (47%), Gaps = 19/212 (8%)
Query: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIR 87
+TLQ +LGCE+ DN++ K+ +G++ + F W P A W++
Sbjct: 111 YTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKA 170
Query: 88 ARQNRAYLERDCPAQLQQLLELGRGVLDQQ---------------VTTLRCRALNYYPQN 132
A + +L CP +L++ LE GRG L+ + + L C A ++YP
Sbjct: 171 ANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPE 230
Query: 133 ITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLI 192
+ +++L++ + D PN DG++ +L V G+E Y C V+H GL QPL
Sbjct: 231 LQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLR 287
Query: 193 VIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 223
V E P+ S LV+G++ G+ + G L
Sbjct: 288 VELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 98.6 bits (244), Expect = 4e-21
Identities = 61/212 (28%), Positives = 101/212 (47%), Gaps = 19/212 (8%)
Query: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIR 87
+TLQ +LGCE+ DN++ K+ +G++ + F W P A W++
Sbjct: 111 YTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKA 170
Query: 88 ARQNRAYLERDCPAQLQQLLELGRGVLDQQ---------------VTTLRCRALNYYPQN 132
A + +L CP +L++ LE GRG L+ + + L C A ++YP
Sbjct: 171 ANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPE 230
Query: 133 ITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLI 192
+ +++L++ + D PN DG++ +L V G+E Y C V+H GL QPL
Sbjct: 231 LQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLR 287
Query: 193 VIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 223
V E P+ S LV+G++ G+ + G L
Sbjct: 288 VELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 82.8 bits (203), Expect = 3e-16
Identities = 73/258 (28%), Positives = 110/258 (42%), Gaps = 27/258 (10%)
Query: 2 GPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTE---GYWKYGYDGQDHL 58
G R L+L +L T V +GR + G N TE G +Y Y+ +++
Sbjct: 12 GLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGM-CYFTNGTERVRGVTRYIYNREEYA 70
Query: 59 EFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV 118
F D +RA P P W K + RA L+ C Q LEL R L ++V
Sbjct: 71 RFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQ--LEL-RTTLQRRV 127
Query: 119 -----------------TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 161
L C ++YP I ++W ++ Q + ++ NGD T
Sbjct: 128 EPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQE-ETTGVVSTPLIRNGDWT 186
Query: 162 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 220
+Q + L + P YTC VEHP L P+IV W + S + ++SGI FV+ ++F+
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSESAQSKMLSGIGGFVLGLIFL 245
Query: 221 GILFIILRKRQGSRGAMG 238
G+ II + Q G
Sbjct: 246 GLGLIIHHRSQKGEEPQG 263
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 82.4 bits (202), Expect = 3e-16
Identities = 72/251 (28%), Positives = 109/251 (43%), Gaps = 27/251 (10%)
Query: 2 GPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTE---GYWKYGYDGQDHL 58
G R L+L +L T V +GR + G N TE G +Y Y+ +++
Sbjct: 12 GLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGM-CYFTNGTERVRGVTRYIYNREEYA 70
Query: 59 EFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV 118
F D +RA P P W K + RA L+ C Q LEL R L ++V
Sbjct: 71 RFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQ--LEL-RTTLQRRV 127
Query: 119 -----------------TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 161
L C ++YP I ++W ++ Q + ++ NGD T
Sbjct: 128 EPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQE-ETTGVVSTPLIRNGDWT 186
Query: 162 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 220
+Q + L + P YTC VEHP L P+IV W + S + ++SGI FV+ ++F+
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSESAQSKMLSGIGGFVLGLIFL 245
Query: 221 GILFIILRKRQ 231
G+ II + Q
Sbjct: 246 GLGLIIHHRSQ 256
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 79.0 bits (193), Expect = 4e-15
Identities = 71/251 (28%), Positives = 108/251 (43%), Gaps = 27/251 (10%)
Query: 2 GPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTE---GYWKYGYDGQDHL 58
G R L+L +L T V +GR + G N TE G +Y Y+ +++
Sbjct: 12 GLRVATVTLMLAMLSTPVAEGRDSPEDFVFQFKGM-CYFTNGTERVRGVTRYIYNREEYA 70
Query: 59 EFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV 118
F D +RA P P W K + RA ++ C Q LEL R L ++V
Sbjct: 71 RFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCRHNYQ--LEL-RTTLQRRV 127
Query: 119 -----------------TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 161
L C ++YP I ++W ++ Q A ++ NGD T
Sbjct: 128 EPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTP-LIRNGDWT 186
Query: 162 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 220
+Q + L + P YTC VEHP L P+ V W + S + ++SGI FV+ ++F+
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGFVLGLIFL 245
Query: 221 GILFIILRKRQ 231
G+ II + Q
Sbjct: 246 GLGLIIHHRSQ 256
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 77.8 bits (190), Expect = 8e-15
Identities = 71/252 (28%), Positives = 116/252 (46%), Gaps = 22/252 (8%)
Query: 3 PRARPALLLLMLLQTAVLQGRLL-QSHTLQVILGCEMQEDNSTEGYW-KYGYDGQDHLEF 60
PR LLM+L T+V+QGR +++ Q C N T+ + +Y Y+ ++ F
Sbjct: 10 PRTVALTALLMVLLTSVVQGRATPENYLFQGRQEC--YAFNGTQRFLERYIYNREEFARF 67
Query: 61 CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDC--------PAQLQQLLELGRG 112
D ++RA P W K + RA +R C P LQ+ ++
Sbjct: 68 DSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVN 127
Query: 113 VLD------QQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 166
V Q L C ++YP +I ++W + Q A +++ NGD T+Q +
Sbjct: 128 VSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVST-NLIRNGDWTFQILV 186
Query: 167 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFI-GI-LF 224
L + P + YTCQVEH LD P+ V W+ + S + ++G FV+ L I G+ +F
Sbjct: 187 MLEMTPQQGDVYTCQVEHTSLDSPVTVEWK-AQSDSARSKTLTGAGGFVLGLIICGVGIF 245
Query: 225 IILRKRQGSRGA 236
+ R ++ RG+
Sbjct: 246 MHRRSKKVQRGS 257
>gi|150418002 major histocompatibility complex, class II, DQ beta 1
precursor [Homo sapiens]
Length = 261
Score = 75.1 bits (183), Expect = 5e-14
Identities = 54/201 (26%), Positives = 90/201 (44%), Gaps = 23/201 (11%)
Query: 49 KYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLE 108
+Y Y+ +++ F D +RA P+ P W K RA L+ C +
Sbjct: 61 RYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAF- 119
Query: 109 LGRGVLDQQV-----------------TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEP 151
RG+L ++V L C ++YP I ++W ++ Q A
Sbjct: 120 --RGILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVST 177
Query: 152 KDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGI 211
++ NGD T+Q + L + P YTC VEHP L P+ V W + S + ++SG+
Sbjct: 178 P-LIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGV 235
Query: 212 AVFVV-ILFIGILFIILRKRQ 231
FV+ ++F+G+ II ++ Q
Sbjct: 236 GGFVLGLIFLGLGLIIRQRSQ 256
>gi|52630344 major histocompatibility complex, class II, DR beta 4
precursor [Homo sapiens]
Length = 266
Score = 75.1 bits (183), Expect = 5e-14
Identities = 59/219 (26%), Positives = 99/219 (45%), Gaps = 21/219 (9%)
Query: 36 CEMQEDNSTEGYW---KYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 92
CE N TE W +Y Y+ +++ + D +++A P W K + R
Sbjct: 42 CECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRR 101
Query: 93 AYLERDCPAQ--------LQQLLELGRGVLDQQVTTLR------CRALNYYPQNITMKWL 138
A ++ C +Q+ ++ V + L+ C +YP +I ++W
Sbjct: 102 AEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWF 161
Query: 139 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 198
++ Q A ++ NGD T+Q + L P + YTCQVEHP + PL V W +
Sbjct: 162 RNGQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWS-A 219
Query: 199 PSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 235
S + ++SG+ FV+ +LF+G LFI R ++G G
Sbjct: 220 RSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSG 258
>gi|239758090 PREDICTED: major histocompatibility complex, class II,
DR beta 4 [Homo sapiens]
Length = 278
Score = 75.1 bits (183), Expect = 5e-14
Identities = 59/219 (26%), Positives = 99/219 (45%), Gaps = 21/219 (9%)
Query: 36 CEMQEDNSTEGYW---KYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 92
CE N TE W +Y Y+ +++ + D +++A P W K + R
Sbjct: 54 CECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRR 113
Query: 93 AYLERDCPAQ--------LQQLLELGRGVLDQQVTTLR------CRALNYYPQNITMKWL 138
A ++ C +Q+ ++ V + L+ C +YP +I ++W
Sbjct: 114 AEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWF 173
Query: 139 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 198
++ Q A ++ NGD T+Q + L P + YTCQVEHP + PL V W +
Sbjct: 174 RNGQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWS-A 231
Query: 199 PSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 235
S + ++SG+ FV+ +LF+G LFI R ++G G
Sbjct: 232 RSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSG 270
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.140 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,667,146
Number of Sequences: 37866
Number of extensions: 518961
Number of successful extensions: 1462
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 1254
Number of HSP's gapped (non-prelim): 147
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.