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Search of human proteins with 21040347
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
(334 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 696 0.0
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 687 0.0
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 626 e-180
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 465 e-131
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 456 e-128
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 269 3e-72
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 268 4e-72
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 268 4e-72
gi|4504417 major histocompatibility complex, class I-related [Ho... 207 1e-53
gi|24797067 major histocompatibility complex, class I, A precurs... 199 4e-51
gi|17986001 major histocompatibility complex, class I, B precurs... 196 2e-50
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 193 2e-49
gi|52630342 major histocompatibility complex, class I, C precurs... 187 9e-48
gi|149158702 major histocompatibility complex, class I, F isofor... 186 3e-47
gi|149158698 major histocompatibility complex, class I, F isofor... 186 3e-47
gi|4504415 major histocompatibility complex, class I, G precurso... 186 3e-47
gi|62912479 major histocompatibility complex, class I, E precurs... 184 1e-46
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 183 2e-46
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 127 1e-29
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 120 2e-27
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 116 3e-26
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 116 3e-26
gi|21040357 hemochromatosis protein isoform 11 precursor [Homo s... 99 5e-21
gi|149158700 major histocompatibility complex, class I, F isofor... 92 5e-19
gi|4502649 CD1D antigen precursor [Homo sapiens] 84 2e-16
gi|239740918 PREDICTED: similar to major histocompatibility comp... 78 1e-14
gi|239740920 PREDICTED: similar to major histocompatibility comp... 77 2e-14
gi|150418002 major histocompatibility complex, class II, DQ beta... 75 8e-14
gi|52630344 major histocompatibility complex, class II, DR beta ... 75 8e-14
gi|239758090 PREDICTED: major histocompatibility complex, class ... 75 8e-14
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 696 bits (1797), Expect = 0.0
Identities = 334/334 (100%), Positives = 334/334 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Query: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR
Sbjct: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
Query: 181 AYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPK 240
AYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPK
Sbjct: 181 AYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPK 240
Query: 241 DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIA 300
DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIA
Sbjct: 241 DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIA 300
Query: 301 VFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334
VFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 301 VFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 687 bits (1772), Expect = 0.0
Identities = 334/348 (95%), Positives = 334/348 (95%), Gaps = 14/348 (4%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Query: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR
Sbjct: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
Query: 181 AYLERDCPAQLQQLLELGRGVLDQQ--------------VTTLRCRALNYYPQNITMKWL 226
AYLERDCPAQLQQLLELGRGVLDQQ VTTLRCRALNYYPQNITMKWL
Sbjct: 181 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 240
Query: 227 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 286
KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS
Sbjct: 241 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 300
Query: 287 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334
PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 301 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 626 bits (1615), Expect = e-180
Identities = 310/348 (89%), Positives = 310/348 (89%), Gaps = 37/348 (10%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV
Sbjct: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 97
Query: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR
Sbjct: 98 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 157
Query: 181 AYLERDCPAQLQQLLELGRGVLDQQ--------------VTTLRCRALNYYPQNITMKWL 226
AYLERDCPAQLQQLLELGRGVLDQQ VTTLRCRALNYYPQNITMKWL
Sbjct: 158 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 217
Query: 227 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 286
KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS
Sbjct: 218 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 277
Query: 287 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334
PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 278 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 465 bits (1197), Expect = e-131
Identities = 220/221 (99%), Positives = 221/221 (100%)
Query: 114 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 173
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 174 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMD 233
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMD
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMD 145
Query: 234 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 293
AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI
Sbjct: 146 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 205
Query: 294 GVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334
GVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 206 GVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 246
Score = 59.3 bits (142), Expect = 5e-09
Identities = 31/52 (59%), Positives = 37/52 (71%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGY 52
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGY 52
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 456 bits (1172), Expect = e-128
Identities = 220/235 (93%), Positives = 221/235 (94%), Gaps = 14/235 (5%)
Query: 114 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 173
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 174 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV--------------TTLRCRALNYYPQ 219
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV TTLRCRALNYYPQ
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 145
Query: 220 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 279
NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL
Sbjct: 146 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 205
Query: 280 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334
IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 206 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 260
Score = 59.3 bits (142), Expect = 5e-09
Identities = 31/52 (59%), Positives = 37/52 (71%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGY 52
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGY 52
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 269 bits (687), Expect = 3e-72
Identities = 129/130 (99%), Positives = 130/130 (100%)
Query: 205 QVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQ 264
+VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQ
Sbjct: 113 KVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQ 172
Query: 265 RYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGA 324
RYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGA
Sbjct: 173 RYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGA 232
Query: 325 MGHYVLAERE 334
MGHYVLAERE
Sbjct: 233 MGHYVLAERE 242
Score = 234 bits (597), Expect = 8e-62
Identities = 113/113 (100%), Positives = 113/113 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 268 bits (686), Expect = 4e-72
Identities = 129/129 (100%), Positives = 129/129 (100%)
Query: 206 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 265
VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR
Sbjct: 40 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 99
Query: 266 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 325
YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM
Sbjct: 100 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 159
Query: 326 GHYVLAERE 334
GHYVLAERE
Sbjct: 160 GHYVLAERE 168
Score = 50.1 bits (118), Expect = 3e-06
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 268 bits (686), Expect = 4e-72
Identities = 129/129 (100%), Positives = 129/129 (100%)
Query: 206 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 265
VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR
Sbjct: 128 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 187
Query: 266 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 325
YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM
Sbjct: 188 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 247
Query: 326 GHYVLAERE 334
GHYVLAERE
Sbjct: 248 GHYVLAERE 256
Score = 234 bits (597), Expect = 8e-62
Identities = 113/113 (100%), Positives = 113/113 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 207 bits (526), Expect = 1e-53
Identities = 116/323 (35%), Positives = 178/323 (55%), Gaps = 19/323 (5%)
Query: 11 LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEP 70
LL L+ +++ R+HSL Y +G S+ G+ F ++GYVD YD +R+ EP
Sbjct: 8 LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEP 67
Query: 71 RTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDN 130
R PW++ ++ W + +Q L+GW MF V+ + ++NHS SHT Q ++GCE+ ED
Sbjct: 68 RAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSG-SHTYQRMIGCELLEDG 126
Query: 131 STEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQ 190
ST G+ +Y YDGQD L F DTL W A + A K WE ++ + +LE +C A
Sbjct: 127 STTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAW 186
Query: 191 LQQLLELGRGVLDQQ---------------VTTLRCRALNYYPQNITMKWLKDKQPMDAK 235
L++ LE G+ L + VT L C+A +YP I M W+K+ + + +
Sbjct: 187 LKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEI-VQ 245
Query: 236 EFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGV 295
E + D+LP+GDGTYQ W ++ + P Y+C VEH G+ L V E S + LV+
Sbjct: 246 EIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQE-SETIPLVMKA 304
Query: 296 ISGIAVFVVILFIGILFIILRKR 318
+SG V V++L G+ ++ R+R
Sbjct: 305 VSGSIVLVIVL-AGVGVLVWRRR 326
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 199 bits (505), Expect = 4e-51
Identities = 120/345 (34%), Positives = 179/345 (51%), Gaps = 23/345 (6%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
P LLL+L L SHS+ Y F S G F A+GYVDD FV +D +
Sbjct: 6 PRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAA 65
Query: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
S+R+EPR PW+ + W Q ++++K VD T+ +N S+ SHT+Q++ G
Sbjct: 66 SQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYG 124
Query: 124 CEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C++ D GY + YDG+D++ D W AA+ A TK +WE A Q RAY
Sbjct: 125 CDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH-EAEQLRAY 183
Query: 183 LERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYPQNITMKWLK 227
L+ C L++ LE G+ L + TLRC AL +YP IT+ W +
Sbjct: 184 LDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQR 243
Query: 228 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 287
D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +PL + WE S
Sbjct: 244 DGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSS 302
Query: 288 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLA 331
T+ ++G+I+G+ + ++ ++ ++ +R+ S G Y A
Sbjct: 303 QPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQA 347
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 196 bits (499), Expect = 2e-50
Identities = 117/342 (34%), Positives = 177/342 (51%), Gaps = 23/342 (6%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
P +LL+L L SHS+ Y + S G F ++GYVDD FV +D +
Sbjct: 6 PRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAA 65
Query: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
S R EPR PW+ + W + +Q K + +N S+ SHTLQ + G
Sbjct: 66 SPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYG 124
Query: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C++ D G+ +Y YDG+D++ D W AA+ A T+ +WE + A Q RAY
Sbjct: 125 CDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR-EAEQRRAY 183
Query: 183 LERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYPQNITMKWLK 227
LE +C L++ LE G+ L++ TLRC AL +YP IT+ W +
Sbjct: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243
Query: 228 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 287
D + ++ E + P GD T+Q W + VP GEEQRYTC V+H GL +PL + WEPS
Sbjct: 244 DGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSS 302
Query: 288 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 328
T+ ++G+++G+AV V++ ++ ++ +R+ S G G Y
Sbjct: 303 QSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY 344
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 193 bits (491), Expect = 2e-49
Identities = 116/319 (36%), Positives = 170/319 (53%), Gaps = 23/319 (7%)
Query: 27 SHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMW 84
SHSL Y + S LG F ++GYVDD FV +D +S R EPR PW+ + W
Sbjct: 39 SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYW 97
Query: 85 LQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDG 142
+ ++ +K F V T+ +N S+ SHTLQ++ GC++ D G+ + YDG
Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
Query: 143 QDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVL 202
+D++ D W AA+ A TK + E RQ R YLE C L++ LE G+ L
Sbjct: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQ-RNYLEGRCVEGLRRYLETGKDAL 216
Query: 203 ---------------DQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGD 247
++ TLRC AL +YP+ I++ W ++ + ++ E + P+GD
Sbjct: 217 LRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGD 275
Query: 248 GTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILF 307
GT+Q W L VP GEEQRYTC+V+H GL +PL + WEP + L++G+I G+ + VV L
Sbjct: 276 GTFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALV 335
Query: 308 IGILFIILRKRQGSRGAMG 326
G + I +KR G G G
Sbjct: 336 AGAV-IWRKKRSGREGREG 353
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 187 bits (476), Expect = 9e-48
Identities = 122/346 (35%), Positives = 176/346 (50%), Gaps = 27/346 (7%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
M PRA LLL+L L SHS+ Y S G F ++GYVDD FV
Sbjct: 4 MAPRA----LLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVR 59
Query: 61 YDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHT 117
+D + S R EPR PWV + W + +Q K V + +N S++ SHT
Sbjct: 60 FDSDAASPRGEPRAPWVEQE-GPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHT 118
Query: 118 LQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRA 176
LQ + GC++ D GY + YDG+D++ D W AA+ A T+ + E + A
Sbjct: 119 LQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARA-A 177
Query: 177 RQNRAYLERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYPQNI 221
Q RAYLE C L++ LE G+ L + TLRC AL +YP I
Sbjct: 178 EQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEI 237
Query: 222 TMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIV 281
T+ W +D + ++ E + P GDGT+Q W + VP G+EQRYTC ++H GL +PL +
Sbjct: 238 TLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTL 296
Query: 282 IWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 326
WEPS T+ ++G+++G+AV VV+ +G + + R+ S G G
Sbjct: 297 SWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKG 342
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 186 bits (471), Expect = 3e-47
Identities = 116/342 (33%), Positives = 173/342 (50%), Gaps = 23/342 (6%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
R+EPR PWV Q W + K V ++ +N S+ SHTLQ + G
Sbjct: 63 IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNG 121
Query: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C+M D GY ++ YDG+D++ D W AA+ A T+ +E + A + R Y
Sbjct: 122 CDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEY-AEEFRTY 180
Query: 183 LERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYPQNITMKWLK 227
LE +C L++ LE G+ L + TLRC AL +YP IT+ W +
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 228 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 287
D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QPLI+ WE SP
Sbjct: 241 DGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSP 299
Query: 288 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 328
T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 300 QPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 186 bits (471), Expect = 3e-47
Identities = 116/342 (33%), Positives = 173/342 (50%), Gaps = 23/342 (6%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
R+EPR PWV Q W + K V ++ +N S+ SHTLQ + G
Sbjct: 63 IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNG 121
Query: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C+M D GY ++ YDG+D++ D W AA+ A T+ +E + A + R Y
Sbjct: 122 CDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEY-AEEFRTY 180
Query: 183 LERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYPQNITMKWLK 227
LE +C L++ LE G+ L + TLRC AL +YP IT+ W +
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 228 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 287
D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QPLI+ WE SP
Sbjct: 241 DGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSP 299
Query: 288 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 328
T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 300 QPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 186 bits (471), Expect = 3e-47
Identities = 115/335 (34%), Positives = 174/335 (51%), Gaps = 23/335 (6%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P L L+L L SHS+ Y S G F A+GYVDD FV +D +S
Sbjct: 6 PRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSA 65
Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK-ESHTLQVILG 123
R+EPR PWV + W + +++ K ++ T+ +N S+ SHTLQ ++G
Sbjct: 66 CPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIG 124
Query: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C++ D GY +Y YDG+D+L D W AA+ A +K + E + A Q RAY
Sbjct: 125 CDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANV-AEQRRAY 183
Query: 183 LERDCPAQLQQLLELGRGVLDQ------QVT---------TLRCRALNYYPQNITMKWLK 227
LE C L + LE G+ +L + VT TLRC AL +YP I + W +
Sbjct: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
Query: 228 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 287
D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +PL++ W+ S
Sbjct: 244 DGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSS 302
Query: 288 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 321
T+ ++G+++G+ V ++ + +L +++ S
Sbjct: 303 LPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 184 bits (467), Expect = 1e-46
Identities = 114/343 (33%), Positives = 176/343 (51%), Gaps = 23/343 (6%)
Query: 10 LLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE--SRR 67
LLL+L + L SHSL Y S G F ++GYVDD FV +D++ S R
Sbjct: 6 LLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPR 65
Query: 68 VEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILGCEM 126
+ PR PW+ S+ W + ++S + +F V+ T+ +N S+ SHTLQ + GCE+
Sbjct: 66 MVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCEL 124
Query: 127 QEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLER 185
D GY ++ YDG+D+L D W A + A ++ + A RAYLE
Sbjct: 125 GPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDASEAEHQRAYLED 183
Query: 186 DCPAQLQQLLELGRGVL---------------DQQVTTLRCRALNYYPQNITMKWLKDKQ 230
C L + LE G+ L TLRC AL +YP IT+ W +D +
Sbjct: 184 TCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGE 243
Query: 231 PMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGT 290
++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P+ + W+P+ T
Sbjct: 244 G-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPT 302
Query: 291 L-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 332
+ ++G+I+G+ + ++ ++ ++ +++ S G G Y AE
Sbjct: 303 IPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAE 345
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 183 bits (465), Expect = 2e-46
Identities = 109/302 (36%), Positives = 164/302 (54%), Gaps = 25/302 (8%)
Query: 4 RARPALL-LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYD 62
R P LL LL+LL AV Q +SL Y++ G S+ + F+ALG ++D F Y+
Sbjct: 3 RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62
Query: 63 HESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVIL 122
+ R+ +P W + W Q SQ K + +F I+E +N S SH LQ
Sbjct: 63 SKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRF 121
Query: 123 GCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
GCE++ + S+ +WKY YDG+D++EF + W +P A TK +WE + ++ +AY
Sbjct: 122 GCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAY 181
Query: 183 LERDCPAQLQQLLELGRGVLDQQ------VTT---------LRCRALNYYPQNITMKWLK 227
LE +CPA L++ L+ + +LD+Q VT+ L+C A ++YP I + W +
Sbjct: 182 LEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTR 241
Query: 228 DKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE 284
+ EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+H L QPL+V WE
Sbjct: 242 AGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWE 296
Query: 285 PS 286
S
Sbjct: 297 AS 298
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 127 bits (319), Expect = 1e-29
Identities = 85/289 (29%), Positives = 139/289 (48%), Gaps = 35/289 (12%)
Query: 28 HSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQL 87
HSL Y M S+ S F A G++D Q F+ YD + RR +P+ W + + ++ W
Sbjct: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTE 85
Query: 88 SQSLKGWDHMFTVDFWTIMENHNHSKES----HTLQVILGCEMQEDNSTEGYWKYGYDGQ 143
++ L T + + H K+ H+LQ I CE+ ED+ST G + YDG+
Sbjct: 86 TEDL-------TENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGE 138
Query: 144 ----DHLEFCPDTLDWRA-AEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELG 198
+LE T+ + A+ A W+ ++ + + ++ DC +LQ+ L+ G
Sbjct: 139 LFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSG 198
Query: 199 RGV--------------LDQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLP 244
+ + + T+ CRA ++YP+NIT+ W +D + + DVLP
Sbjct: 199 VAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLP 258
Query: 245 NGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 293
+G+GTYQ W+ + GEEQR+TC +EH G P PSG ++
Sbjct: 259 DGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGT-----HPVPSGKALV 302
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 120 bits (301), Expect = 2e-27
Identities = 89/330 (26%), Positives = 143/330 (43%), Gaps = 37/330 (11%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P LLL + G HSL Y S S F ++D Q F+ D +
Sbjct: 5 PVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKC 64
Query: 67 RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEM 126
R +P+ W + ++ W + ++ L G + T+ + + H+LQ I CE+
Sbjct: 65 RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRM---TLAHIKDQKEGLHSLQEIRVCEI 121
Query: 127 QEDNSTEGYWKYGYDGQDHLEFCPDTLDWRA-----AEPRAWPTKLEWERHKIRARQNRA 181
EDNST + YDG+ L +T +W A+ A + + ++ + +
Sbjct: 122 HEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYH 181
Query: 182 YLERDCPAQLQQLLELG--------------RGVLDQQVTTLRCRALNYYPQNITMKWLK 227
+ DC +L++ L+ G R + T+ CRA +YP NIT+ W +
Sbjct: 182 AMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQ 241
Query: 228 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 287
D + + DVLP+G+GTYQ W+ + GEEQR+TC +EH G P P
Sbjct: 242 DGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHST-----HPVP 296
Query: 288 SG----------TLVIGVISGIAVFVVILF 307
SG T + ++ A+FV+I+F
Sbjct: 297 SGKVLVLQSHWQTFHVSAVAAAAIFVIIIF 326
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 116 bits (290), Expect = 3e-26
Identities = 91/327 (27%), Positives = 145/327 (44%), Gaps = 29/327 (8%)
Query: 3 PRARPALLLLMLLQTAVLQGRL-LRSH-SLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
PR +P L L+L +L G L SH SL Y S G F G++ Q ++
Sbjct: 4 PRPQPWALGLLLF---LLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Y+ EP WV S W + + L+ + +F F + K +TLQ
Sbjct: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL-----GGKGPYTLQG 115
Query: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
+LGCE+ DN++ K+ +G++ + F W P A W++ A +
Sbjct: 116 LLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKEL 175
Query: 181 AYLERDCPAQLQQLLELGRGVLDQQ---------------VTTLRCRALNYYPQNITMKW 225
+L CP +L++ LE GRG L+ + + L C A ++YP + +++
Sbjct: 176 TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRF 235
Query: 226 LKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE- 284
L++ + D PN DG++ +L V G+E Y C V+H GL QPL V E
Sbjct: 236 LRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELES 292
Query: 285 PSPSGTLVIGVISGIAVFVVILFIGIL 311
P+ S LV+G++ G+ + G L
Sbjct: 293 PAKSSVLVVGIVIGVLLLTAAAVGGAL 319
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 116 bits (290), Expect = 3e-26
Identities = 91/327 (27%), Positives = 145/327 (44%), Gaps = 29/327 (8%)
Query: 3 PRARPALLLLMLLQTAVLQGRL-LRSH-SLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
PR +P L L+L +L G L SH SL Y S G F G++ Q ++
Sbjct: 4 PRPQPWALGLLLF---LLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Y+ EP WV S W + + L+ + +F F + K +TLQ
Sbjct: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL-----GGKGPYTLQG 115
Query: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
+LGCE+ DN++ K+ +G++ + F W P A W++ A +
Sbjct: 116 LLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKEL 175
Query: 181 AYLERDCPAQLQQLLELGRGVLDQQ---------------VTTLRCRALNYYPQNITMKW 225
+L CP +L++ LE GRG L+ + + L C A ++YP + +++
Sbjct: 176 TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRF 235
Query: 226 LKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE- 284
L++ + D PN DG++ +L V G+E Y C V+H GL QPL V E
Sbjct: 236 LRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELES 292
Query: 285 PSPSGTLVIGVISGIAVFVVILFIGIL 311
P+ S LV+G++ G+ + G L
Sbjct: 293 PAKSSVLVVGIVIGVLLLTAAAVGGAL 319
>gi|21040357 hemochromatosis protein isoform 11 precursor [Homo
sapiens]
Length = 76
Score = 99.0 bits (245), Expect = 5e-21
Identities = 50/51 (98%), Positives = 51/51 (100%)
Query: 284 EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334
+PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 26 QPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 76
Score = 51.6 bits (122), Expect = 1e-06
Identities = 29/53 (54%), Positives = 37/53 (69%), Gaps = 3/53 (5%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYV 53
MGPRARPALLLLMLLQTAVLQGRLL+ L +G G+++F + ++
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQPSPSGTLVIGVIS---GIAVFVVILFI 50
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 92.4 bits (228), Expect = 5e-19
Identities = 66/202 (32%), Positives = 96/202 (47%), Gaps = 6/202 (2%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
R+EPR PWV Q W + K V ++ +N S+ SHTLQ + G
Sbjct: 63 IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNG 121
Query: 124 CEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C+M D GY ++ YDG+D++ D W AA+ A T+ +E + A + R Y
Sbjct: 122 CDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEY-AEEFRTY 180
Query: 183 LERDCPAQLQQLLELGRGVLDQ 204
LE +C L++ LE G+ L +
Sbjct: 181 LEGECLELLRRYLENGKETLQR 202
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 84.0 bits (206), Expect = 2e-16
Identities = 76/289 (26%), Positives = 123/289 (42%), Gaps = 44/289 (15%)
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTL-- 118
+ ++S V PW S Q W L + + FT D + E + S+ L
Sbjct: 58 WSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRD---VKEFAKMLRLSYPLEL 114
Query: 119 QVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL--------EWE 170
QV GCE+ N++ ++ + G+D L F W + L +W
Sbjct: 115 QVSAGCEVHPGNASNNFFHVAFQGKDILSF--QGTSWEPTQEAPLWVNLAIQVLNQDKWT 172
Query: 171 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT----------------LRCRAL 214
R ++ N CP + LLE G+ L +QV L C
Sbjct: 173 RETVQWLLNGT-----CPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVS 227
Query: 215 NYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPG 274
+YP+ + +KW++ +Q + P D+LPN D T+ TL V GE +C+V+H
Sbjct: 228 GFYPKPVWVKWMRGEQEQQGTQ--PGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285
Query: 275 LD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILR-KRQGS 321
L+ Q +++ W S + +G+I+ +AV +LF+ I+ R KRQ S
Sbjct: 286 LEGQDIVLYWGGSYTS---MGLIA-LAVLACLLFLLIVGFTSRFKRQTS 330
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 77.8 bits (190), Expect = 1e-14
Identities = 63/218 (28%), Positives = 96/218 (44%), Gaps = 26/218 (11%)
Query: 130 NSTE---GYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 186
N TE G +Y Y+ +++ F D +RA P P W K + RA L+
Sbjct: 51 NGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTV 110
Query: 187 CPAQLQQLLELGRGVLDQQV-----------------TTLRCRALNYYPQNITMKWLKDK 229
C Q LEL R L ++V L C ++YP I ++W ++
Sbjct: 111 CRHNYQ--LEL-RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRND 167
Query: 230 QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG 289
Q + ++ NGD T+Q + L + P YTC VEHP L P+IV W + S
Sbjct: 168 QE-ETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSE 225
Query: 290 TLVIGVISGIAVFVV-ILFIGILFIILRKRQGSRGAMG 326
+ ++SGI FV+ ++F+G+ II + Q G
Sbjct: 226 SAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKGEEPQG 263
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 77.4 bits (189), Expect = 2e-14
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 26/211 (12%)
Query: 130 NSTE---GYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 186
N TE G +Y Y+ +++ F D +RA P P W K + RA L+
Sbjct: 51 NGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTV 110
Query: 187 CPAQLQQLLELGRGVLDQQV-----------------TTLRCRALNYYPQNITMKWLKDK 229
C Q LEL R L ++V L C ++YP I ++W ++
Sbjct: 111 CRHNYQ--LEL-RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRND 167
Query: 230 QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG 289
Q + ++ NGD T+Q + L + P YTC VEHP L P+IV W + S
Sbjct: 168 QE-ETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSE 225
Query: 290 TLVIGVISGIAVFVV-ILFIGILFIILRKRQ 319
+ ++SGI FV+ ++F+G+ II + Q
Sbjct: 226 SAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQ 256
>gi|150418002 major histocompatibility complex, class II, DQ beta 1
precursor [Homo sapiens]
Length = 261
Score = 75.1 bits (183), Expect = 8e-14
Identities = 54/201 (26%), Positives = 90/201 (44%), Gaps = 23/201 (11%)
Query: 137 KYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLE 196
+Y Y+ +++ F D +RA P+ P W K RA L+ C +
Sbjct: 61 RYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAF- 119
Query: 197 LGRGVLDQQV-----------------TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEP 239
RG+L ++V L C ++YP I ++W ++ Q A
Sbjct: 120 --RGILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVST 177
Query: 240 KDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGI 299
++ NGD T+Q + L + P YTC VEHP L P+ V W + S + ++SG+
Sbjct: 178 P-LIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGV 235
Query: 300 AVFVV-ILFIGILFIILRKRQ 319
FV+ ++F+G+ II ++ Q
Sbjct: 236 GGFVLGLIFLGLGLIIRQRSQ 256
>gi|52630344 major histocompatibility complex, class II, DR beta 4
precursor [Homo sapiens]
Length = 266
Score = 75.1 bits (183), Expect = 8e-14
Identities = 59/219 (26%), Positives = 99/219 (45%), Gaps = 21/219 (9%)
Query: 124 CEMQEDNSTEGYW---KYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
CE N TE W +Y Y+ +++ + D +++A P W K + R
Sbjct: 42 CECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRR 101
Query: 181 AYLERDCPAQ--------LQQLLELGRGVLDQQVTTLR------CRALNYYPQNITMKWL 226
A ++ C +Q+ ++ V + L+ C +YP +I ++W
Sbjct: 102 AEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWF 161
Query: 227 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 286
++ Q A ++ NGD T+Q + L P + YTCQVEHP + PL V W +
Sbjct: 162 RNGQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWS-A 219
Query: 287 PSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 323
S + ++SG+ FV+ +LF+G LFI R ++G G
Sbjct: 220 RSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSG 258
>gi|239758090 PREDICTED: major histocompatibility complex, class II,
DR beta 4 [Homo sapiens]
Length = 278
Score = 75.1 bits (183), Expect = 8e-14
Identities = 59/219 (26%), Positives = 99/219 (45%), Gaps = 21/219 (9%)
Query: 124 CEMQEDNSTEGYW---KYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
CE N TE W +Y Y+ +++ + D +++A P W K + R
Sbjct: 54 CECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRR 113
Query: 181 AYLERDCPAQ--------LQQLLELGRGVLDQQVTTLR------CRALNYYPQNITMKWL 226
A ++ C +Q+ ++ V + L+ C +YP +I ++W
Sbjct: 114 AEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWF 173
Query: 227 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 286
++ Q A ++ NGD T+Q + L P + YTCQVEHP + PL V W +
Sbjct: 174 RNGQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWS-A 231
Query: 287 PSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 323
S + ++SG+ FV+ +LF+G LFI R ++G G
Sbjct: 232 RSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSG 270
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,822,920
Number of Sequences: 37866
Number of extensions: 651589
Number of successful extensions: 1799
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 1569
Number of HSP's gapped (non-prelim): 142
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.