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Search of human proteins with 21040343
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
(256 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 526 e-150
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 489 e-138
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 339 2e-93
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 309 2e-84
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 297 7e-81
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 297 7e-81
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 295 2e-80
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 268 3e-72
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 119 2e-27
gi|17986001 major histocompatibility complex, class I, B precurs... 118 6e-27
gi|52630342 major histocompatibility complex, class I, C precurs... 117 1e-26
gi|149158702 major histocompatibility complex, class I, F isofor... 116 2e-26
gi|149158698 major histocompatibility complex, class I, F isofor... 116 2e-26
gi|62912479 major histocompatibility complex, class I, E precurs... 110 1e-24
gi|24797067 major histocompatibility complex, class I, A precurs... 108 6e-24
gi|4504415 major histocompatibility complex, class I, G precurso... 102 3e-22
gi|21040357 hemochromatosis protein isoform 11 precursor [Homo s... 99 4e-21
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 88 8e-18
gi|4504417 major histocompatibility complex, class I-related [Ho... 86 4e-17
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 83 2e-16
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 79 5e-15
gi|4504399 major histocompatibility complex, class II, DM beta p... 71 8e-13
gi|239740918 PREDICTED: similar to major histocompatibility comp... 69 3e-12
gi|239740920 PREDICTED: similar to major histocompatibility comp... 69 4e-12
gi|169168591 PREDICTED: similar to major histocompatibility comp... 68 7e-12
gi|52630344 major histocompatibility complex, class II, DR beta ... 68 9e-12
gi|239758090 PREDICTED: major histocompatibility complex, class ... 68 9e-12
gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo ... 67 1e-11
gi|239740859 PREDICTED: similar to major histocompatibility comp... 67 1e-11
gi|239740857 PREDICTED: similar to major histocompatibility comp... 67 1e-11
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 526 bits (1356), Expect = e-150
Identities = 256/256 (100%), Positives = 256/256 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVPPLVKV 120
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVPPLVKV
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVPPLVKV 120
Query: 121 THHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV 180
THHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV
Sbjct: 121 THHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV 180
Query: 181 PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 240
PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR
Sbjct: 181 PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 240
Query: 241 QGSRGAMGHYVLAERE 256
QGSRGAMGHYVLAERE
Sbjct: 241 QGSRGAMGHYVLAERE 256
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 489 bits (1258), Expect = e-138
Identities = 242/256 (94%), Positives = 242/256 (94%), Gaps = 14/256 (5%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVPPLVKV 120
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKV
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKV------ 114
Query: 121 THHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV 180
TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV
Sbjct: 115 --------TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV 166
Query: 181 PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 240
PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR
Sbjct: 167 PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 226
Query: 241 QGSRGAMGHYVLAERE 256
QGSRGAMGHYVLAERE
Sbjct: 227 QGSRGAMGHYVLAERE 242
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 339 bits (869), Expect = 2e-93
Identities = 182/261 (69%), Positives = 198/261 (75%), Gaps = 6/261 (2%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY F
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
Query: 61 YDH--ESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN---HSKVP 115
+ R EPR W + + ++ Q+ + ++E +VP
Sbjct: 61 CPDTLDWRAAEPRA-WPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVP 119
Query: 116 PLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGW 175
PLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGW
Sbjct: 120 PLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGW 179
Query: 176 ITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFI 235
ITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFI
Sbjct: 180 ITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFI 239
Query: 236 ILRKRQGSRGAMGHYVLAERE 256
ILRKRQGSRGAMGHYVLAERE
Sbjct: 240 ILRKRQGSRGAMGHYVLAERE 260
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 309 bits (791), Expect = 2e-84
Identities = 170/259 (65%), Positives = 189/259 (72%), Gaps = 16/259 (6%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY F
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
Query: 61 YDH--ESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVPPLV 118
+ R EPR W + + ++ Q+ +E +++ L+
Sbjct: 61 CPDTLDWRAAEPRA-WPTKLEWERHKIRARQNR------------AYLERDCPAQLQQLL 107
Query: 119 KVTHHVTSS-VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWIT 177
++ V VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWIT
Sbjct: 108 ELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWIT 167
Query: 178 LAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIIL 237
LAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIIL
Sbjct: 168 LAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIIL 227
Query: 238 RKRQGSRGAMGHYVLAERE 256
RKRQGSRGAMGHYVLAERE
Sbjct: 228 RKRQGSRGAMGHYVLAERE 246
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 297 bits (760), Expect = 7e-81
Identities = 143/144 (99%), Positives = 144/144 (100%)
Query: 113 KVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 172
+VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY
Sbjct: 182 QVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 241
Query: 173 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI 232
QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI
Sbjct: 242 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI 301
Query: 233 LFIILRKRQGSRGAMGHYVLAERE 256
LFIILRKRQGSRGAMGHYVLAERE
Sbjct: 302 LFIILRKRQGSRGAMGHYVLAERE 325
Score = 174 bits (440), Expect = 9e-44
Identities = 89/113 (78%), Positives = 89/113 (78%), Gaps = 23/113 (20%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 90
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 297 bits (760), Expect = 7e-81
Identities = 143/144 (99%), Positives = 144/144 (100%)
Query: 113 KVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 172
+VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY
Sbjct: 205 QVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 264
Query: 173 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI 232
QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI
Sbjct: 265 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI 324
Query: 233 LFIILRKRQGSRGAMGHYVLAERE 256
LFIILRKRQGSRGAMGHYVLAERE
Sbjct: 325 LFIILRKRQGSRGAMGHYVLAERE 348
Score = 234 bits (597), Expect = 5e-62
Identities = 113/113 (100%), Positives = 113/113 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 295 bits (756), Expect = 2e-80
Identities = 142/143 (99%), Positives = 143/143 (100%)
Query: 114 VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
+PPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ
Sbjct: 26 LPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
Query: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 233
GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL
Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
Query: 234 FIILRKRQGSRGAMGHYVLAERE 256
FIILRKRQGSRGAMGHYVLAERE
Sbjct: 146 FIILRKRQGSRGAMGHYVLAERE 168
Score = 50.1 bits (118), Expect = 2e-06
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 268 bits (686), Expect = 3e-72
Identities = 129/129 (100%), Positives = 129/129 (100%)
Query: 128 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 187
VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR
Sbjct: 206 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 265
Query: 188 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 247
YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM
Sbjct: 266 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 325
Query: 248 GHYVLAERE 256
GHYVLAERE
Sbjct: 326 GHYVLAERE 334
Score = 234 bits (597), Expect = 5e-62
Identities = 113/113 (100%), Positives = 113/113 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 119 bits (299), Expect = 2e-27
Identities = 58/135 (42%), Positives = 84/135 (62%), Gaps = 3/135 (2%)
Query: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
PP VTHH ++ TLRC AL +YP+ I++ W ++ + ++ E + P+GDGT+Q
Sbjct: 221 PPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGDGTFQ 279
Query: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 233
W L VP GEEQRYTC+V+H GL +PL + WEP + L++G+I G+ + VV L G +
Sbjct: 280 KWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV 339
Query: 234 FIILRKRQGSRGAMG 248
I +KR G G G
Sbjct: 340 -IWRKKRSGREGREG 353
Score = 53.1 bits (126), Expect = 2e-07
Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 27 SHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMW 84
SHSL Y + S LG F ++GYVDD FV +D +S R EPR PW+ + W
Sbjct: 39 SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYW 97
Query: 85 LQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
+ ++ +K F V T+ +N S+
Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSE 126
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 118 bits (295), Expect = 6e-27
Identities = 56/138 (40%), Positives = 85/138 (61%), Gaps = 3/138 (2%)
Query: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
PP VTHH ++ TLRC AL +YP IT+ W +D + ++ E + P GD T+Q
Sbjct: 208 PPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQ 266
Query: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232
W + VP GEEQRYTC V+H GL +PL + WEPS T+ ++G+++G+AV V++ +
Sbjct: 267 KWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAV 326
Query: 233 LFIILRKRQGSRGAMGHY 250
+ ++ +R+ S G G Y
Sbjct: 327 VAAVMCRRKSSGGKGGSY 344
Score = 49.7 bits (117), Expect = 3e-06
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
P +LL+L L SHS+ Y + S G F ++GYVDD FV +D +
Sbjct: 6 PRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAA 65
Query: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLK 92
S R EPR PW+ + W + +Q K
Sbjct: 66 SPREEPRAPWIEQE-GPEYWDRNTQIYK 92
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 117 bits (293), Expect = 1e-26
Identities = 57/136 (41%), Positives = 83/136 (61%), Gaps = 3/136 (2%)
Query: 115 PPLVKVTHHVTSS-VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
PP VTHH S TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q
Sbjct: 208 PPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQ 266
Query: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232
W + VP G+EQRYTC ++H GL +PL + WEPS T+ ++G+++G+AV VV+ +G
Sbjct: 267 KWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGA 326
Query: 233 LFIILRKRQGSRGAMG 248
+ + R+ S G G
Sbjct: 327 VVTAMMCRRKSSGGKG 342
Score = 48.1 bits (113), Expect = 7e-06
Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
M PRA LLL+L L SHS+ Y S G F ++GYVDD FV
Sbjct: 4 MAPRA----LLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVR 59
Query: 61 YDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLK 92
+D + S R EPR PWV + W + +Q K
Sbjct: 60 FDSDAASPRGEPRAPWVEQE-GPEYWDRETQKYK 92
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 116 bits (291), Expect = 2e-26
Identities = 55/138 (39%), Positives = 84/138 (60%), Gaps = 3/138 (2%)
Query: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
PP V HH ++ TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q
Sbjct: 205 PPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQ 263
Query: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232
W + VPPGEEQRYTC V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ +
Sbjct: 264 KWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAV 323
Query: 233 LFIILRKRQGSRGAMGHY 250
+ ++ +++ S G Y
Sbjct: 324 VAAVMWRKKSSDRNRGSY 341
Score = 45.8 bits (107), Expect = 4e-05
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
Query: 67 --RVEPRTPWVSSRISSQMW 84
R+EPR PWV Q W
Sbjct: 63 IPRMEPREPWVEQE-GPQYW 81
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 116 bits (291), Expect = 2e-26
Identities = 55/138 (39%), Positives = 84/138 (60%), Gaps = 3/138 (2%)
Query: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
PP V HH ++ TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q
Sbjct: 205 PPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQ 263
Query: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232
W + VPPGEEQRYTC V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ +
Sbjct: 264 KWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAV 323
Query: 233 LFIILRKRQGSRGAMGHY 250
+ ++ +++ S G Y
Sbjct: 324 VAAVMWRKKSSDRNRGSY 341
Score = 45.8 bits (107), Expect = 4e-05
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
Query: 67 --RVEPRTPWVSSRISSQMW 84
R+EPR PWV Q W
Sbjct: 63 IPRMEPREPWVEQE-GPQYW 81
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 110 bits (275), Expect = 1e-24
Identities = 53/142 (37%), Positives = 86/142 (60%), Gaps = 3/142 (2%)
Query: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
PP VTHH ++ TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q
Sbjct: 205 PPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEG-HTQDTELVETRPAGDGTFQ 263
Query: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232
W + VP GEEQRYTC V+H GL +P+ + W+P+ T+ ++G+I+G+ + ++ +
Sbjct: 264 KWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAV 323
Query: 233 LFIILRKRQGSRGAMGHYVLAE 254
+ ++ +++ S G G Y AE
Sbjct: 324 VAAVIWRKKSSGGKGGSYSKAE 345
Score = 55.8 bits (133), Expect = 3e-08
Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
Query: 10 LLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE--SRR 67
LLL+L + L SHSL Y S G F ++GYVDD FV +D++ S R
Sbjct: 6 LLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPR 65
Query: 68 VEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
+ PR PW+ S+ W + ++S + +F V+ T+ +N S+
Sbjct: 66 MVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSE 110
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 108 bits (269), Expect = 6e-24
Identities = 53/141 (37%), Positives = 83/141 (58%), Gaps = 3/141 (2%)
Query: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
PP +THH ++ TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q
Sbjct: 208 PPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQ 266
Query: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232
W + VP GEEQRYTC V+H GL +PL + WE S T+ ++G+I+G+ + ++ +
Sbjct: 267 KWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAV 326
Query: 233 LFIILRKRQGSRGAMGHYVLA 253
+ ++ +R+ S G Y A
Sbjct: 327 VAAVMWRRKSSDRKGGSYTQA 347
Score = 63.2 bits (152), Expect = 2e-10
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
P LLL+L L SHS+ Y F S G F A+GYVDD FV +D +
Sbjct: 6 PRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAA 65
Query: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
S+R+EPR PW+ + W Q ++++K VD T+ +N S+
Sbjct: 66 SQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSE 113
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 102 bits (254), Expect = 3e-22
Identities = 50/131 (38%), Positives = 78/131 (59%), Gaps = 3/131 (2%)
Query: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
PP VTHH V TLRC AL +YP I + W +D + ++ E + P GDGT+Q
Sbjct: 208 PPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQ 266
Query: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232
W + VP GEEQRYTC V+H GL +PL++ W+ S T+ ++G+++G+ V ++
Sbjct: 267 KWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAA 326
Query: 233 LFIILRKRQGS 243
+ +L +++ S
Sbjct: 327 VAAVLWRKKSS 337
Score = 53.1 bits (126), Expect = 2e-07
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 3/109 (2%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P L L+L L SHS+ Y S G F A+GYVDD FV +D +S
Sbjct: 6 PRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSA 65
Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
R+EPR PWV + W + +++ K ++ T+ +N S+
Sbjct: 66 CPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSE 113
>gi|21040357 hemochromatosis protein isoform 11 precursor [Homo
sapiens]
Length = 76
Score = 99.0 bits (245), Expect = 4e-21
Identities = 50/51 (98%), Positives = 51/51 (100%)
Query: 206 EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 256
+PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 26 QPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 76
Score = 51.6 bits (122), Expect = 7e-07
Identities = 29/53 (54%), Positives = 37/53 (69%), Gaps = 3/53 (5%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYV 53
MGPRARPALLLLMLLQTAVLQGRLL+ L +G G+++F + ++
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQPSPSGTLVIGVIS---GIAVFVVILFI 50
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 87.8 bits (216), Expect = 8e-18
Identities = 48/127 (37%), Positives = 67/127 (52%), Gaps = 16/127 (12%)
Query: 114 VPPLVKVTHHVTSSVT-TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 172
VPP+V VT S T+ CRA +YP NIT+ W +D + + DVLP+G+GTY
Sbjct: 205 VPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTY 264
Query: 173 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG----------TLVIGVISGIA 222
Q W+ + GEEQR+TC +EH G P PSG T + ++ A
Sbjct: 265 QTWVATRICQGEEQRFTCYMEHSGNHST-----HPVPSGKVLVLQSHWQTFHVSAVAAAA 319
Query: 223 VFVVILF 229
+FV+I+F
Sbjct: 320 IFVIIIF 326
Score = 30.8 bits (68), Expect = 1.2
Identities = 22/87 (25%), Positives = 35/87 (40%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P LLL + G HSL Y S S F ++D Q F+ D +
Sbjct: 5 PVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKC 64
Query: 67 RVEPRTPWVSSRISSQMWLQLSQSLKG 93
R +P+ W + ++ W + ++ L G
Sbjct: 65 RAKPQGQWAEDVLGNKTWDRETRDLTG 91
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 85.5 bits (210), Expect = 4e-17
Identities = 49/127 (38%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Query: 115 PPLVKVTHHVT-SSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
PPLV+V T VT L C+A +YP I M W+K+ + + +E + D+LP+GDGTYQ
Sbjct: 203 PPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQ 261
Query: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 233
W ++ + P Y+C VEH G+ L V E S + LV+ +SG V V++L G+
Sbjct: 262 AWASIELDPQSSNLYSCHVEHCGVHMVLQVPQE-SETIPLVMKAVSGSIVLVIVL-AGVG 319
Query: 234 FIILRKR 240
++ R+R
Sbjct: 320 VLVWRRR 326
Score = 75.1 bits (183), Expect = 6e-14
Identities = 35/102 (34%), Positives = 58/102 (56%)
Query: 11 LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEP 70
LL L+ +++ R+HSL Y +G S+ G+ F ++GYVD YD +R+ EP
Sbjct: 8 LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEP 67
Query: 71 RTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS 112
R PW++ ++ W + +Q L+GW MF V+ + ++NHS
Sbjct: 68 RAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS 109
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 83.2 bits (204), Expect = 2e-16
Identities = 42/103 (40%), Positives = 60/103 (58%), Gaps = 6/103 (5%)
Query: 114 VPPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 172
VPP+V VT V+ T+ CRA ++YP+NIT+ W +D + + DVLP+G+GTY
Sbjct: 205 VPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTY 264
Query: 173 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 215
Q W+ + GEEQR+TC +EH G P PSG ++
Sbjct: 265 QTWVATRIRQGEEQRFTCYMEHSGNHGT-----HPVPSGKALV 302
Score = 42.0 bits (97), Expect = 5e-04
Identities = 20/57 (35%), Positives = 31/57 (54%)
Query: 28 HSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMW 84
HSL Y M S+ S F A G++D Q F+ YD + RR +P+ W + + ++ W
Sbjct: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTW 82
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 78.6 bits (192), Expect = 5e-15
Identities = 41/98 (41%), Positives = 55/98 (56%), Gaps = 9/98 (9%)
Query: 115 PPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPK---DVLPNGDG 170
PP V VT H L+C A ++YP I + W + + EP+ DVL NG+G
Sbjct: 206 PPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQ-----EPELRGDVLHNGNG 260
Query: 171 TYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 208
TYQ W+ +AVPP + Y+C V+H L QPL+V WE S
Sbjct: 261 TYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298
Score = 46.6 bits (109), Expect = 2e-05
Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Query: 4 RARPALL-LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYD 62
R P LL LL+LL AV Q +SL Y++ G S+ + F+ALG ++D F Y+
Sbjct: 3 RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62
Query: 63 HESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS 112
+ R+ +P W + W Q SQ K + +F I+E +N S
Sbjct: 63 SKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYYNDS 111
>gi|4504399 major histocompatibility complex, class II, DM beta
precursor [Homo sapiens]
Length = 263
Score = 71.2 bits (173), Expect = 8e-13
Identities = 42/138 (30%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
Query: 99 TVDFWTIMENHNHSKVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKE 158
T FW + N + K T T L C +YP +T+ W K+ + +
Sbjct: 101 TQPFWGSLTNRTRPPSVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHS 160
Query: 159 FEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEP--SPSGTLVIG 216
K PNGD TYQ LA+ P YTC VEH G +P++ W P SP TL +
Sbjct: 161 SAHKTAQPNGDWTYQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPMQTLKVS 220
Query: 217 VIS-GIAVFVVILFIGIL 233
V + + + ++I +G++
Sbjct: 221 VSAVTLGLGLIIFSLGVI 238
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 69.3 bits (168), Expect = 3e-12
Identities = 65/260 (25%), Positives = 114/260 (43%), Gaps = 21/260 (8%)
Query: 2 GPRARPALLLLMLLQTAVLQGRLLRSHSLHYL-----FMGASEQDLGLSLF----EALGY 52
G R L+L +L T V +GR ++ F +E+ G++ + E
Sbjct: 12 GLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNREEYAR 71
Query: 53 VDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS 112
D + V+ R V P P + +SQ + L ++ D + ++ +
Sbjct: 72 FDSDVGVY-----RAVTPLGPPAAEYWNSQKEV-LERTRAELDTVCRHNYQLELRTTLQR 125
Query: 113 KVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGD 169
+V P V ++ T ++ L C ++YP I ++W ++ Q + ++ NGD
Sbjct: 126 RVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQE-ETTGVVSTPLIRNGD 184
Query: 170 GTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-IL 228
T+Q + L + P YTC VEHP L P+IV W + S + ++SGI FV+ ++
Sbjct: 185 WTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSESAQSKMLSGIGGFVLGLI 243
Query: 229 FIGILFIILRKRQGSRGAMG 248
F+G+ II + Q G
Sbjct: 244 FLGLGLIIHHRSQKGEEPQG 263
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 68.9 bits (167), Expect = 4e-12
Identities = 64/253 (25%), Positives = 113/253 (44%), Gaps = 21/253 (8%)
Query: 2 GPRARPALLLLMLLQTAVLQGRLLRSHSLHYL-----FMGASEQDLGLSLF----EALGY 52
G R L+L +L T V +GR ++ F +E+ G++ + E
Sbjct: 12 GLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNREEYAR 71
Query: 53 VDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS 112
D + V+ R V P P + +SQ + L ++ D + ++ +
Sbjct: 72 FDSDVGVY-----RAVTPLGPPAAEYWNSQKEV-LERTRAELDTVCRHNYQLELRTTLQR 125
Query: 113 KVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGD 169
+V P V ++ T ++ L C ++YP I ++W ++ Q + ++ NGD
Sbjct: 126 RVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQE-ETTGVVSTPLIRNGD 184
Query: 170 GTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-IL 228
T+Q + L + P YTC VEHP L P+IV W + S + ++SGI FV+ ++
Sbjct: 185 WTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSESAQSKMLSGIGGFVLGLI 243
Query: 229 FIGILFIILRKRQ 241
F+G+ II + Q
Sbjct: 244 FLGLGLIIHHRSQ 256
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 68.2 bits (165), Expect = 7e-12
Identities = 65/254 (25%), Positives = 114/254 (44%), Gaps = 23/254 (9%)
Query: 2 GPRARPALLLLMLLQTAVLQGR------LLRSHSLHYLFMGASEQDLGLSLF----EALG 51
G R L+L +L T V +GR + + + Y F +E+ G++ + E
Sbjct: 12 GLRVATVTLMLAMLSTPVAEGRDSPEDFVFQFKGMCY-FTNGTERVRGVTRYIYNREEYA 70
Query: 52 YVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNH 111
D + V+ R V P P + +SQ + L ++ D + ++ +
Sbjct: 71 RFDSDVGVY-----RAVTPLGPPAAEYWNSQKEV-LERTRASVDTVCRHNYQLELRTTLQ 124
Query: 112 SKVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNG 168
+V P V ++ T ++ L C ++YP I ++W ++ Q A ++ NG
Sbjct: 125 RRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTP-LIRNG 183
Query: 169 DGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-I 227
D T+Q + L + P YTC VEHP L P+ V W + S + ++SGI FV+ +
Sbjct: 184 DWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGFVLGL 242
Query: 228 LFIGILFIILRKRQ 241
+F+G+ II + Q
Sbjct: 243 IFLGLGLIIHHRSQ 256
>gi|52630344 major histocompatibility complex, class II, DR beta 4
precursor [Homo sapiens]
Length = 266
Score = 67.8 bits (164), Expect = 9e-12
Identities = 47/136 (34%), Positives = 69/136 (50%), Gaps = 12/136 (8%)
Query: 112 SKVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 171
SK PL HH L C +YP +I ++W ++ Q A ++ NGD T
Sbjct: 133 SKTQPL---QHH-----NLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWT 183
Query: 172 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 230
+Q + L P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+
Sbjct: 184 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWS-ARSESAQSKMLSGVGGFVLGLLFL 242
Query: 231 GI-LFIILRKRQGSRG 245
G LFI R ++G G
Sbjct: 243 GTGLFIYFRNQKGHSG 258
>gi|239758090 PREDICTED: major histocompatibility complex, class II,
DR beta 4 [Homo sapiens]
Length = 278
Score = 67.8 bits (164), Expect = 9e-12
Identities = 47/136 (34%), Positives = 69/136 (50%), Gaps = 12/136 (8%)
Query: 112 SKVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 171
SK PL HH L C +YP +I ++W ++ Q A ++ NGD T
Sbjct: 145 SKTQPL---QHH-----NLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWT 195
Query: 172 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 230
+Q + L P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+
Sbjct: 196 FQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWS-ARSESAQSKMLSGVGGFVLGLLFL 254
Query: 231 GI-LFIILRKRQGSRG 245
G LFI R ++G G
Sbjct: 255 GTGLFIYFRNQKGHSG 270
>gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo
sapiens]
Length = 266
Score = 67.4 bits (163), Expect = 1e-11
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 12/136 (8%)
Query: 112 SKVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 171
SK PL HH L C +YP +I ++W ++ Q + ++ NGD T
Sbjct: 133 SKTQPL---QHH-----NLLVCSVSGFYPGSIEVRWFRNGQE-EKTGVVSTGLIHNGDWT 183
Query: 172 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 230
+Q + L P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+
Sbjct: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFL 242
Query: 231 GI-LFIILRKRQGSRG 245
G LFI R ++G G
Sbjct: 243 GAGLFIYFRNQKGHSG 258
>gi|239740859 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 3 isoform 1 [Homo sapiens]
Length = 267
Score = 67.4 bits (163), Expect = 1e-11
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 12/136 (8%)
Query: 112 SKVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 171
SK PL HH L C +YP +I ++W ++ Q + ++ NGD T
Sbjct: 134 SKTQPL---QHH-----NLLVCSVSGFYPGSIEVRWFRNGQE-EKTGVVSTGLIHNGDWT 184
Query: 172 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 230
+Q + L P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+
Sbjct: 185 FQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFL 243
Query: 231 GI-LFIILRKRQGSRG 245
G LFI R ++G G
Sbjct: 244 GAGLFIYFRNQKGHSG 259
>gi|239740857 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 3 isoform 2 [Homo sapiens]
Length = 266
Score = 67.4 bits (163), Expect = 1e-11
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 12/136 (8%)
Query: 112 SKVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 171
SK PL HH L C +YP +I ++W ++ Q + ++ NGD T
Sbjct: 133 SKTQPL---QHH-----NLLVCSVSGFYPGSIEVRWFRNGQE-EKTGVVSTGLIHNGDWT 183
Query: 172 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 230
+Q + L P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+
Sbjct: 184 FQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFL 242
Query: 231 GI-LFIILRKRQGSRG 245
G LFI R ++G G
Sbjct: 243 GAGLFIYFRNQKGHSG 258
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,401,643
Number of Sequences: 37866
Number of extensions: 473185
Number of successful extensions: 1382
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 1192
Number of HSP's gapped (non-prelim): 156
length of query: 256
length of database: 18,247,518
effective HSP length: 100
effective length of query: 156
effective length of database: 14,460,918
effective search space: 2255903208
effective search space used: 2255903208
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.