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Search of human proteins with 208022661
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|208022661 hypothetical protein LOC57701 [Homo sapiens]
(1334 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|208022661 hypothetical protein LOC57701 [Homo sapiens] 2759 0.0
gi|126362969 Nck-associated protein 5 isoform 2 [Homo sapiens] 122 3e-27
gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens] 122 3e-27
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 95 4e-19
gi|163965366 nascent polypeptide-associated complex alpha subuni... 92 3e-18
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 89 3e-17
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 87 8e-17
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 86 2e-16
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 85 4e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 82 3e-15
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 82 4e-15
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 81 6e-15
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 80 1e-14
gi|150170670 piccolo isoform 2 [Homo sapiens] 80 1e-14
gi|150378539 piccolo isoform 1 [Homo sapiens] 80 1e-14
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 80 2e-14
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 80 2e-14
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 80 2e-14
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 78 5e-14
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 78 5e-14
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 78 5e-14
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 78 5e-14
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 77 8e-14
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 77 8e-14
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 77 8e-14
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 77 1e-13
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 77 1e-13
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 77 1e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 76 2e-13
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 74 7e-13
>gi|208022661 hypothetical protein LOC57701 [Homo sapiens]
Length = 1334
Score = 2759 bits (7151), Expect = 0.0
Identities = 1334/1334 (100%), Positives = 1334/1334 (100%)
Query: 1 MSEAMDQPAGGPGNPRPGEGDDGSMEPGTCQELLHRLRELEAENSALAQANENQRETYER 60
MSEAMDQPAGGPGNPRPGEGDDGSMEPGTCQELLHRLRELEAENSALAQANENQRETYER
Sbjct: 1 MSEAMDQPAGGPGNPRPGEGDDGSMEPGTCQELLHRLRELEAENSALAQANENQRETYER 60
Query: 61 CLDEVANHVVQALLNQKDLREECIKLKKRVFDLERQNQMLSALFQQKLQLTTGSLPQIPL 120
CLDEVANHVVQALLNQKDLREECIKLKKRVFDLERQNQMLSALFQQKLQLTTGSLPQIPL
Sbjct: 61 CLDEVANHVVQALLNQKDLREECIKLKKRVFDLERQNQMLSALFQQKLQLTTGSLPQIPL 120
Query: 121 TPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDAL 180
TPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDAL
Sbjct: 121 TPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDAL 180
Query: 181 SPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPPQPEPSPW 240
SPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPPQPEPSPW
Sbjct: 181 SPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPPQPEPSPW 240
Query: 241 APCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSS 300
APCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSS
Sbjct: 241 APCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSS 300
Query: 301 SSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQS 360
SSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQS
Sbjct: 301 SSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQS 360
Query: 361 SSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSR 420
SSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSR
Sbjct: 361 SSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSR 420
Query: 421 PGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQL 480
PGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQL
Sbjct: 421 PGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQL 480
Query: 481 PRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQS 540
PRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQS
Sbjct: 481 PRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQS 540
Query: 541 ALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRS 600
ALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRS
Sbjct: 541 ALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRS 600
Query: 601 PGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTP 660
PGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTP
Sbjct: 601 PGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTP 660
Query: 661 LRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLE 720
LRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLE
Sbjct: 661 LRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLE 720
Query: 721 AKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKS 780
AKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKS
Sbjct: 721 AKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKS 780
Query: 781 RLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESP 840
RLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESP
Sbjct: 781 RLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESP 840
Query: 841 KPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQG 900
KPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQG
Sbjct: 841 KPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQG 900
Query: 901 QERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGAGGGSPLRREVKMEARK 960
QERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGAGGGSPLRREVKMEARK
Sbjct: 901 QERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGAGGGSPLRREVKMEARK 960
Query: 961 LEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPNTGLGQVQGQLAGMYQ 1020
LEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPNTGLGQVQGQLAGMYQ
Sbjct: 961 LEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPNTGLGQVQGQLAGMYQ 1020
Query: 1021 GADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGC 1080
GADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGC
Sbjct: 1021 GADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGC 1080
Query: 1081 GKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTP 1140
GKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTP
Sbjct: 1081 GKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTP 1140
Query: 1141 SKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPA 1200
SKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPA
Sbjct: 1141 SKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPA 1200
Query: 1201 LLPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLP 1260
LLPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLP
Sbjct: 1201 LLPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLP 1260
Query: 1261 RTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGPPGLETSESLS 1320
RTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGPPGLETSESLS
Sbjct: 1261 RTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGPPGLETSESLS 1320
Query: 1321 DSLYDSLSSCGSQG 1334
DSLYDSLSSCGSQG
Sbjct: 1321 DSLYDSLSSCGSQG 1334
>gi|126362969 Nck-associated protein 5 isoform 2 [Homo sapiens]
Length = 590
Score = 122 bits (305), Expect = 3e-27
Identities = 63/85 (74%), Positives = 71/85 (83%)
Query: 33 LLHRLRELEAENSALAQANENQRETYERCLDEVANHVVQALLNQKDLREECIKLKKRVFD 92
LL RL+ LEAENSALA NENQRE YERCLDEVAN VVQALL QKDLREEC+KLK RVFD
Sbjct: 185 LLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFD 244
Query: 93 LERQNQMLSALFQQKLQLTTGSLPQ 117
LE+QN+ LS LFQQ+++ T+ L Q
Sbjct: 245 LEQQNRTLSILFQQRVRPTSDLLLQ 269
Score = 52.4 bits (124), Expect = 3e-06
Identities = 36/101 (35%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 1081 GKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTP 1140
GK K E + +D++A+ V SH RTLDSGIGTFP PD G+ T
Sbjct: 358 GKNLRKRVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTG 417
Query: 1141 SKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVP 1181
P +P + P + RA TLEREVP
Sbjct: 418 RYLCQPDSPEDAEP---LLPLQSALSAVSSMRAQTLEREVP 455
>gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens]
Length = 1909
Score = 122 bits (305), Expect = 3e-27
Identities = 63/85 (74%), Positives = 71/85 (83%)
Query: 33 LLHRLRELEAENSALAQANENQRETYERCLDEVANHVVQALLNQKDLREECIKLKKRVFD 92
LL RL+ LEAENSALA NENQRE YERCLDEVAN VVQALL QKDLREEC+KLK RVFD
Sbjct: 185 LLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFD 244
Query: 93 LERQNQMLSALFQQKLQLTTGSLPQ 117
LE+QN+ LS LFQQ+++ T+ L Q
Sbjct: 245 LEQQNRTLSILFQQRVRPTSDLLLQ 269
Score = 118 bits (296), Expect = 3e-26
Identities = 239/949 (25%), Positives = 337/949 (35%), Gaps = 187/949 (19%)
Query: 352 GDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMG 411
G P SS PP + G PEA G S P P S+ +
Sbjct: 894 GSRSRPAIESSDSGEPPT--------RDEHCGSGPEA-----GVKSPSPPPPPGRSVSLL 940
Query: 412 AGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEA---QGPLLP---------SPARGLKFL 459
A RP + +S + +K + PS + PLL +PA
Sbjct: 941 A-------RPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQR 993
Query: 460 KLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGL 519
K P + K P P SP+ +R P +PS LG ++SP+ +G+
Sbjct: 994 KKPSVAFKKPIFTHPMPSPEAVIQTRCPAH------APSSSFTVMALGPPKVSPK--RGV 1045
Query: 520 P-TSPSPCYTTPD-STQLRPPQSALST----TLSPGPVVSPCYENILDLSRSTFRGPSPE 573
P TSP TP L+ P+ + ST ++ VSP + L+ S ST
Sbjct: 1046 PKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSAST------P 1099
Query: 574 PPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYG--SPQEKSLD------- 624
P PS L V P + S SP + P+G S EK L
Sbjct: 1100 PKPSFLGVNESPSSQVS---------SSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGL 1150
Query: 625 KAGSESPHPGRRT---PG-------NSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTG 674
K +SP R++ PG N + K S + + P + A + T
Sbjct: 1151 KVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTL 1210
Query: 675 PEG-ALGSEKNGVPARPGTEK---TRGPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVA 730
P+ A GS +G+P ++ + PG G D +R + + + A
Sbjct: 1211 PDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVD-----NRSMRRSLSSSKPHLKPA 1265
Query: 731 LGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCL-TKVELAKSRLAGALCPQ 789
LG N K + + +S+HS G + P+ + T++ + +L Q
Sbjct: 1266 LGMNGAKAR---------SHSFSTHS-GDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQ 1315
Query: 790 VPRT---PAKVPT-----SAPSLGKPNKSP----------------HSSPTKLPSKSPTK 825
T P K P+ S PS+G+P+ P H SP+KLP + P K
Sbjct: 1316 NSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPK 1375
Query: 826 ----VVPR-------------PGAPLVTKESPKPDKGKGPPW-ADC-------GSTTAQS 860
++P P A + P D+ PP DC G T S
Sbjct: 1376 SEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPS 1435
Query: 861 T----------------PLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERA 904
T TD L+P IEEKVM I+ENV + Q Q +
Sbjct: 1436 TFETSSTSKLETSGRHPDASATATDAVSSEAPLSP--TIEEKVMLCIQENVEKGQVQTKP 1493
Query: 905 PGAEVKHRNTSSIASWFGLKKSKLPALNRR--------TEATKNKEGAGGGSPLRREVKM 956
E K + S ASWFG +KS+LPAL+ R E K G L+ E K
Sbjct: 1494 TSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKK 1553
Query: 957 EARKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPNTGLGQVQGQLA 1016
E +K E + ++L+ +D + A + S R P +A
Sbjct: 1554 EKKKPELQCETENELI---KDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHSPVA 1610
Query: 1017 GMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSDPK----SPWPACGPRNG 1072
DTFM +LLNRVD K P + SS S G
Sbjct: 1611 --CSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGNHKK 1668
Query: 1073 LVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPP 1132
+ P E + +D++A+ V SH RTLDSGIGTFP P
Sbjct: 1669 NMKIKADMEVPKDSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLP 1728
Query: 1133 DHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVP 1181
D G+ T P +P + P + RA TLEREVP
Sbjct: 1729 DSGNRSTGRYLCQPDSPEDAEP---LLPLQSALSAVSSMRAQTLEREVP 1774
Score = 48.5 bits (114), Expect = 4e-05
Identities = 109/485 (22%), Positives = 168/485 (34%), Gaps = 70/485 (14%)
Query: 440 SPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSP 499
SP A G L +R +K P E P P+ S QLP +SR+P R S
Sbjct: 836 SPALAPGKL----SRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQ 891
Query: 500 LLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENI 559
R E S G PT C + P++ P SP P P ++
Sbjct: 892 TPGSRSRPAIESSDSGEP--PTRDEHCGSGPEAGVKSP---------SPPP---PPGRSV 937
Query: 560 LDLSRSTF-RGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSP 618
L+R ++ P+P S +VP+ T P +L+ P P
Sbjct: 938 SLLARPSYDYSPAPSSTKSETRVPSE---TARTPFKSPLLKGISAPVISSNP-------- 986
Query: 619 QEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRD-RLAALGKLKTGPEG 677
+ + + P + P + PS + + P P + ALG K P
Sbjct: 987 ---ATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSP-- 1041
Query: 678 ALGSEKNGVPARPGTEKTRGPGKS-GESAGDMVPSIHRPLEQLEAKGGIRGAVA-LGTNS 735
K GVP + P + G + PS H PLE +K G L ++
Sbjct: 1042 -----KRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSA 1096
Query: 736 LKQQEPGLMG---DPGARVYSSHSMGARVDLEPVSPRSCLTKVELA-KSRLAGALCPQVP 791
+P +G P ++V SS S + SP C + E K+RL L
Sbjct: 1097 STPPKPSFLGVNESPSSQVSSSSSSSSPAKSHN-SPHGCQSAHEKGLKTRLPVGL----- 1150
Query: 792 RTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWA 851
KV +P L + + + +P K + V KP+ K P A
Sbjct: 1151 ----KVLMKSPQLLRKSST-------VPGKHEKDSLNEASKSSVAVNKSKPEDSKNP--A 1197
Query: 852 DCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAEVKH 911
T + +P SQ LA +E + + +E ++ G++ ++
Sbjct: 1198 SMEITAGERNVTLP----DSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRR 1253
Query: 912 RNTSS 916
+SS
Sbjct: 1254 SLSSS 1258
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 95.1 bits (235), Expect = 4e-19
Identities = 215/837 (25%), Positives = 270/837 (32%), Gaps = 167/837 (19%)
Query: 116 PQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPP 175
P+ L P PP PP P ++ +G P P G+ Q E Q G PG P P
Sbjct: 680 PRGLLGPKGPPG-PPGPPGVTGMDGQ--PGPKGNVGPQGEPGPPGQ--QGNPGAQGLPGP 734
Query: 176 ALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGP-GSP--EPINGELCGP 232
A+ P K L P P P GP G P E GE G
Sbjct: 735 Q-GAIGPPGEKGP----------------LGKPGLPGMPGADGPPGHPGKEGPPGEKGG- 776
Query: 233 PQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNC 292
Q P P P GP + G L G G + + G P + GP
Sbjct: 777 -QGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPG 835
Query: 293 APGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQL-LEDTESYLQAFLAGAAGP-- 349
G G PN P P LG + G+L + Y G GP
Sbjct: 836 PRGEDGPEGPKGRGGPNGDPGP---LGPPGEK----GKLGVPGLPGY-----PGRQGPKG 883
Query: 350 ---------LNGDHPGPGQSSSP-------------DQAPPQLSKSKGLPKSAWGGGTPE 387
NG+ G G P ++ P ++ G PK GG P
Sbjct: 884 SIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPG-PKGNSGGDGP- 941
Query: 388 AHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGP 447
A PG + QGP F G PGHP + + + GPP P GP
Sbjct: 942 AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGP 1001
Query: 448 LLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLP--------RNSRIPCRNSGSDGSPS- 498
P+ G P P P GP LP + P G DG P
Sbjct: 1002 QGPTGETG------PMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGL 1055
Query: 499 -PLLARRGLGG--GELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPC 555
RGL G G L +G +G P P P S R P A GP+ P
Sbjct: 1056 RGFPGDRGLPGPVGALGLKGNEGPPGPPGPA----GSPGERGPAGA------AGPIGIP- 1104
Query: 556 YENILDLSRSTFRGPSPEPPPSPLQVPTYP-QLTLEVPQAPEVLRSPGVPPSPCLPESYP 614
P P+ PP P P + + P + L+ P P P P P
Sbjct: 1105 ------------GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPP 1152
Query: 615 --------YGSPQEKSLDKAGSESPHPGRRTPGNSSKKPS-QGSGRRPGDPGSTPLRDRL 665
G P +K E PG P +P G+ PG G L +
Sbjct: 1153 GEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQK 1212
Query: 666 AALG-KLKTGPEGALGSEKNGVPARPGTEKTRG-------PGKSGESAGDMVPSIHRPLE 717
G + GP G +G + G+P PG + G PG G P P
Sbjct: 1213 GDEGPRGFPGPPGPVGLQ--GLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGP-- 1268
Query: 718 QLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVEL 777
GGI A+G ++ EPG G+PG P P+ + E
Sbjct: 1269 -QGPPGGIGNPGAVG----EKGEPGEAGEPGLPGEGG----------PPGPKG--ERGEK 1311
Query: 778 AKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTK 837
+S +GA P P+ P P P SP P P P P +
Sbjct: 1312 GESGPSGAAGPPGPKGP-------PGDDGPKGSP--GPVGFPGDPGPPGEPGPAG----Q 1358
Query: 838 ESPKPDKG-KGPPWADCGSTTAQSTPLVPGPTDP--SQGPEGLA-PHSAIEEKVMKG 890
+ P DKG G P G T + PGP+ P +GP G A P EK KG
Sbjct: 1359 DGPPGDKGDDGEP----GQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKG 1411
Score = 79.0 bits (193), Expect = 3e-14
Identities = 198/780 (25%), Positives = 256/780 (32%), Gaps = 160/780 (20%)
Query: 165 GGPGPPAAP-PPALDALSPFLRKKAQILEV-LRALE-ETDPLLLCSPATPWRPPGQGPGS 221
G PGP P PP D ++ EV R L E P L P P PPG P
Sbjct: 646 GDPGPSGPPGPPGDDG------ERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPG--PPG 697
Query: 222 PEPINGELCGP-----PQPEPSPWAPCLLLGPGNLG-----GLLHWERLLGGLGGEEDTG 271
++G+ GP PQ EP P PG G GL + +G G + G
Sbjct: 698 VTGMDGQP-GPKGNVGPQGEPGP--------PGQQGNPGAQGLPGPQGAIGPPGEKGPLG 748
Query: 272 RPWGPSR----GPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLN 327
+P P GPP G GP PG P P P + GA R L
Sbjct: 749 KPGLPGMPGADGPPGHPG-KEGP---PGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLK 804
Query: 328 LGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPE 387
G E E F G G + GD G + P+ K +G P G P
Sbjct: 805 -GTKGEKGEDGFPGF-KGDMG-IKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGP- 860
Query: 388 AHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSR--PGHPHSSSQVKSKLQIGPPSPGEAQ 445
PG +G+ +P L + G P GS PG P ++ + + G P P +
Sbjct: 861 ---PG----EKGKLGVPGLPGYPGR-QGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQR 912
Query: 446 GPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRG 505
GP P RG + + T + P P P R P G G P P
Sbjct: 913 GPTGPRGERGPRGI----TGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGP------ 962
Query: 506 LGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRS 565
G P G GLP P T + PP P VV P
Sbjct: 963 --KGPPGPPGKDGLPGHPGQRGETGFQGKTGPP--------GPPGVVGP----------- 1001
Query: 566 TFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLP----ESYPYGSPQEK 621
+GP+ E P + P PG P LP + G P
Sbjct: 1002 --QGPTGETGPMGERGHPGP---------------PGPPGEQGLPGLAGKEGTKGDPGPA 1044
Query: 622 SLDKAGSESP-----HPG-RRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGP 675
L G + P PG R PG +G+ PG PG A + GP
Sbjct: 1045 GL--PGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPG--------PAGSPGERGP 1094
Query: 676 EGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNS 735
GA G G+P RPG + GP + G+ P + + G++G V L +
Sbjct: 1095 AGAAG--PIGIPGRPGPQGPPGPAGEKGAPGEKGP------QGPAGRDGLQGPVGLPGPA 1146
Query: 736 LKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPA 795
PG GD G + G++ D P P P+ P
Sbjct: 1147 GPVGPPGEDGDKG-EIGEPGQKGSKGDKGEQGPPG-----------------PTGPQGPI 1188
Query: 796 KVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGS 855
P + + G+P + P P P+ + P P KG + G
Sbjct: 1189 GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKG----ETGD 1244
Query: 856 TTAQSTPLVPGPTDPS--------QGPE-GLAPHSAIEEKVMKGIEENVLRLQGQERAPG 906
P PGP PS QGP G+ A+ EK G E L G+ PG
Sbjct: 1245 VGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPG-EAGEPGLPGEGGPPG 1303
Score = 65.5 bits (158), Expect = 3e-10
Identities = 126/444 (28%), Positives = 150/444 (33%), Gaps = 112/444 (25%)
Query: 126 PSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDALSPFLR 185
P P SP G A P+ + PG PGP P PA + +P
Sbjct: 1082 PPGPAGSPGERGPAGAAGPIGI----------------PGRPGPQGPPGPAGEKGAPG-E 1124
Query: 186 KKAQILEVLRALEETDPLLLCSPATPWRPPG----------------------QGPGSPE 223
K Q L+ P+ L PA P PPG QGP P
Sbjct: 1125 KGPQGPAGRDGLQ--GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPT 1182
Query: 224 PINGELCGPPQP-----EPSPWAPCLLLGP-GNLG--------GLLHWERLLGGLGGEED 269
G + G P P EP P L G G+ G G + + L G G + +
Sbjct: 1183 GPQGPI-GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGE 1241
Query: 270 TGR-----PWGPS--RGPPQAQGTSSGPNCAPGSSSSSSS-DEAGDPNEAPSPDTLLGAL 321
TG P GP RGP A G + GP PG + + E G+P EA P L
Sbjct: 1242 TGDVGQMGPPGPPGPRGPSGAPG-ADGPQGPPGGIGNPGAVGEKGEPGEAGEPG--LPGE 1298
Query: 322 ARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAW 381
G+ E ES +GAAGP PGP + PP KG P
Sbjct: 1299 GGPPGPKGERGEKGESGP----SGAAGP-----PGP-------KGPPGDDGPKGSPGPVG 1342
Query: 382 GGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSP 441
G P PG + GP GD PG S GPP
Sbjct: 1343 FPGDPGP--PGEPGPAGQDGP---------PGDKGDDGEPGQTGSPGPTGEPGPSGPPGK 1391
Query: 442 GEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLL 501
GP P +G K K E P GP + PQ G+ G P P
Sbjct: 1392 RGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGP-IGPQ------------GAPGKPGPD- 1437
Query: 502 ARRGLGGGELSPEGAQGLPTSPSP 525
RG+ G P G QGLP SP P
Sbjct: 1438 GLRGIPG----PVGEQGLPGSPGP 1457
Score = 45.1 bits (105), Expect = 5e-04
Identities = 105/383 (27%), Positives = 126/383 (32%), Gaps = 71/383 (18%)
Query: 112 TGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPA 171
TG + Q+ P P +P +GP + G++ E PG PG
Sbjct: 1242 TGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAG-EPGLPGEGG 1300
Query: 172 APPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQ-GP-GSPEPINGEL 229
P P K + E E+ P P P PPG GP GSP P+
Sbjct: 1301 PPGP-----------KGERGEK----GESGPSGAAGPPGPKGPPGDDGPKGSPGPVG--F 1343
Query: 230 CGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTS-- 287
G P P P PG+ G + G G TG P GPS GPP +G
Sbjct: 1344 PGDPGPPGEPGPAGQDGPPGDKGD----DGEPGQTGSPGPTGEP-GPS-GPPGKRGPPGP 1397
Query: 288 SGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAA 347
+GP G + P P GA + + L G
Sbjct: 1398 AGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPD--------------GLRGIP 1443
Query: 348 GPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTP-EAHRPGF----GATSEGQGP 402
GP+ G+ PG S PD PP GLP G E PG G E QG
Sbjct: 1444 GPV-GEQGLPG-SPGPD-GPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGE-QGE 1499
Query: 403 LPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKL-------QIGPPSPGEAQGPLLPSPARG 455
GD L PG P SS K + IGPP P GP P A+G
Sbjct: 1500 ---------KGDRGL---PG-PQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKG 1546
Query: 456 LKFLKLPPTSEKSPSPGGPQLSP 478
P P P GP P
Sbjct: 1547 SSGPTGPKGEAGHPGPPGPPGPP 1569
Score = 38.1 bits (87), Expect = 0.057
Identities = 60/254 (23%), Positives = 82/254 (32%), Gaps = 54/254 (21%)
Query: 1096 EMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKT-------- 1147
+ P++ +PTS T + PPP G+ + +T
Sbjct: 365 DQPTDPGAGAEIPTS--------TADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENY 416
Query: 1148 KPPRLDP---PPGVPPARPPPLTKVPR-----RAHTLEREVPGIEE--LLVSGRHPSMPA 1197
P DP P + P P + R ++ P I E +L+ G P P
Sbjct: 417 YDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEG--PPGPE 474
Query: 1198 FPALLPAAPGHRGHETCPDDPCED--------------PGPTPPVQLAKNWTFPNTRAAG 1243
PA LP PG G DP E PGP P L + F AG
Sbjct: 475 GPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGP-PGTMLMLPFRFGGGGDAG 533
Query: 1244 SSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPS-----PTPQGPPFGGSRTPSTSD 1298
S + Q + + L R + P+ P P P GPP G D
Sbjct: 534 SKGPMVSAQESQAQAI------LQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD 587
Query: 1299 MAEEGRVASGGPPG 1312
+ +G GPPG
Sbjct: 588 VGPQGPRGVQGPPG 601
Score = 36.6 bits (83), Expect = 0.17
Identities = 67/257 (26%), Positives = 88/257 (34%), Gaps = 51/257 (19%)
Query: 1072 GLVGPL--QGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTF 1129
G VGP +G PPG P+ +PGRR S+ + P T
Sbjct: 586 GDVGPQGPRGVQGPPG-PAGKPGRRGRAGSDGARGMPGQTG------------------- 625
Query: 1130 PPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREV---PGIEEL 1186
P D G G LP K R DP P PP P + R + PG L
Sbjct: 626 PKGDRGFDGLAG--LPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGL 683
Query: 1187 LVSGRHPSMPAFPAL--LPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGS 1244
L P P P + + PG +G+ P +PG PP Q G+
Sbjct: 684 LGPKGPPGPPGPPGVTGMDGQPGPKGNV----GPQGEPG--PPGQQGNPGAQGLPGPQGA 737
Query: 1245 SSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPP--FGGSRTPSTSDMAEE 1302
P P GLP P A P P +GPP GG P +
Sbjct: 738 IGPPGEKGPLGKPGLPGMPGA-------DGPPGHPG--KEGPPGEKGGQGPP-----GPQ 783
Query: 1303 GRVASGGPPGLETSESL 1319
G + GP G++ ++ +
Sbjct: 784 GPIGYPGPRGVKGADGI 800
Score = 36.2 bits (82), Expect = 0.22
Identities = 41/139 (29%), Positives = 52/139 (37%), Gaps = 15/139 (10%)
Query: 208 PATPWRPPG----QGPGSPEPINGE-----LCGPPQPEPSPWAPCLLLGPGNLGGLLHWE 258
P P PPG +G P+ G L GPP E L GP G +
Sbjct: 1460 PPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPG-EQGEKGDRGLPGPQGSSGPKGEQ 1518
Query: 259 RLLGGLGGEEDTGRPWGPSRGPPQAQGT--SSGPNCAPGSSSSSSSD-EAGDPNEAPSPD 315
+ G G G P P GPP +G SSGP G + G P E P
Sbjct: 1519 GITGPSGPIGPPGPPGLP--GPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPL 1576
Query: 316 TLLGALARRQLNLGQLLED 334
+ + RR ++ QLL+D
Sbjct: 1577 PIQASRTRRNIDASQLLDD 1595
Score = 33.9 bits (76), Expect = 1.1
Identities = 54/210 (25%), Positives = 69/210 (32%), Gaps = 30/210 (14%)
Query: 1130 PPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPAR---PPPLTKVPRRAHTLEREVPGIEEL 1186
PP D G G P + + P +P P PP + P P R+ + G+E
Sbjct: 1361 PPGDKGDDGEPGQT--GSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGP 1418
Query: 1187 ------LVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCED--PGPTPPVQLA--KNWTF 1236
+ P P P L PG G + P P D PGP P L K +
Sbjct: 1419 PGKTGPIGPQGAPGKPG-PDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSG 1477
Query: 1237 PNTRAAGSSSDPLMCPPRQL-----EGLPRTPMAL-PVDRKRSQEPSRPS--------PT 1282
P L+ PP + GLP + P + PS P P
Sbjct: 1478 PKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPG 1537
Query: 1283 PQGPPFGGSRTPSTSDMAEEGRVASGGPPG 1312
P GP + T E G GPPG
Sbjct: 1538 PPGPKGAKGSSGPTGPKGEAGHPGPPGPPG 1567
Score = 33.5 bits (75), Expect = 1.4
Identities = 72/273 (26%), Positives = 86/273 (31%), Gaps = 64/273 (23%)
Query: 1072 GLVGP-----LQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGI 1126
GL GP L+G PPG P E P+ A P+ G R G
Sbjct: 1063 GLPGPVGALGLKGNEGPPGPPGPAGSPGERGPA--GAAGPI--------GIPGRPGPQG- 1111
Query: 1127 GTFPPPDHGSSGTPSKNLPKTKPPR--LDPPPGVP-PARP--PPLTKVPRRAHTLEREVP 1181
PP G G P + P+ R L P G+P PA P PP E
Sbjct: 1112 ---PPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPP------------GEDG 1156
Query: 1182 GIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCEDPGPT----PPVQLAKNWTFP 1237
E+ G+ S P P T P P PGP+ P + F
Sbjct: 1157 DKGEIGEPGQKGSKGDKGEQGPPGP------TGPQGPIGQPGPSGADGEPGPRGQQGLFG 1210
Query: 1238 NTRAAGSSSDPLMCPPRQLEGLPRTP--MALPVDRKRSQEPSRPSPT----------PQG 1285
G P P L+GLP P D + P P P PQG
Sbjct: 1211 QKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQG 1270
Query: 1286 PPFGGSRTPSTSDMAEEGRV------ASGGPPG 1312
PP G + + E G GGPPG
Sbjct: 1271 PPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPG 1303
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 92.0 bits (227), Expect = 3e-18
Identities = 266/1147 (23%), Positives = 369/1147 (32%), Gaps = 204/1147 (17%)
Query: 276 PSRGPPQAQGTSSGPNCAPGSSSSSS-SDEAGDPNEAPSPDTLLGALARRQLNLGQLLED 334
PS P A GT G G S +S+ + A P E P+ D+ A A + L
Sbjct: 735 PSPSLPPA-GTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTL------ 787
Query: 335 TESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFG 394
+LA + PL G S SP P K G TP G
Sbjct: 788 ------TYLADSPSPL-------GVSVSPQTKRPPTKKGSA------GPDTP------IG 822
Query: 395 ATSEGQGP-----LPFLSM-FMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPL 448
S P LP S+ F G+ D+P + P S + + P SP P
Sbjct: 823 NLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPP 882
Query: 449 LPSPARGLKFLKLPPTSEKSPSP-GGPQLS--PQLPRNSRIPCRNSGSDGSPSPLLARRG 505
+P + L P +P+P P LS P+ +R G SPSP A
Sbjct: 883 KETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942
Query: 506 LGGGELSPEGAQGLPT---SPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDL 562
SP+G P+ +P+P TP S + P + +P P +P
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP-PAATPPSPKGGPA 1001
Query: 563 SRSTFRGPSPE--PPPSPLQVPT---YPQLTLEVPQA--PEVLRSP-------GVPPSPC 608
+ S P+P PPSP P +P+ P A P SP G P +P
Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA 1061
Query: 609 LPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGR-RPGDPGSTPLRDRLAA 667
P G P SL A P P TP + P+ S + P P +TP +
Sbjct: 1062 ATLPSPKGGPATPSLKGA----PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK--- 1114
Query: 668 LGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAKGGIRG 727
G L T P + P P P K + P KGG+
Sbjct: 1115 -GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP--------SPKGGLAT 1165
Query: 728 AVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVD--LEPVSPRSCL----------TKV 775
G + P P + + GA P SP+ L T
Sbjct: 1166 PPPKGAPTTPAATP---PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222
Query: 776 ELAKSRLAGALCPQ---VPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPT-----KVV 827
S G P P TPA P S P G P +PT + P+
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPPS-PKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281
Query: 828 PRPGAP---LVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIE 884
P GAP +VT SPK PP T +TP P + + P+G A+
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSPPKG--APTPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339
Query: 885 EKVMKG---IEENVLRLQGQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNK 941
KG + +G P ++ ++ S G + P +R A +
Sbjct: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG-GPAMTPPSPKRGPAIPSP 1398
Query: 942 EG-------------AGGGSPLRREVKMEARKLEAESLNISKLMAKAEDLRRALEEEKAY 988
+G +P+ RE K + ++ + K A + A
Sbjct: 1399 KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458
Query: 989 LSSRARPR-PGGPAPGPN---------TGLGQVQGQLAGMYQGADTFMQQLLNRVDGKEL 1038
SS+ P P P P T + GA T + + KE+
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS--SPKEV 1516
Query: 1039 PSKSWREPKPEYGDFQPVSSDPKSPWPA-CGPRNGLVGPLQGCGKPPGKPS-SEPGRREE 1096
P+ P P ++ PA P+ L+ P P P+ P
Sbjct: 1517 PA----TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572
Query: 1097 MPSEDSLAEP--VPTSHFTACGSLTRTLDSGIGTFPPPDHG------SSGTPSKNLPKTK 1148
PS + P V S + S L T P P + +P K P T
Sbjct: 1573 TPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG-PATP 1631
Query: 1149 PPRLDP--PPGVP------PARPPPLT-----KVPRRAHTL--EREVPGIEELLVSGRHP 1193
P+ P PP P P P +T VP+ + L ++ ++E+LV+
Sbjct: 1632 APKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPE 1691
Query: 1194 SMPAFPALLPAAPGHRGHET----------CPDDPCED----------PGPTPPVQLAKN 1233
S P + AP +G +T CPD ++ P P PVQ +
Sbjct: 1692 STP-----IITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSS 1746
Query: 1234 WTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMA----LPVDRKRSQE---------PSRPS 1280
T A+ S PL PP P T A LP S P PS
Sbjct: 1747 KTAKGKDASHSPKGPL-APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805
Query: 1281 PTPQGPP 1287
P P PP
Sbjct: 1806 PVPTLPP 1812
Score = 90.5 bits (223), Expect = 1e-17
Identities = 216/898 (24%), Positives = 302/898 (33%), Gaps = 157/898 (17%)
Query: 116 PQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPP 175
P P L P PA+PSL P A P G G P PPAA PP
Sbjct: 1057 PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP-----ATPSPKGAPMPPAATPP 1111
Query: 176 A-LDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPPQ 234
+ L+ K A L P P P SP+ G L PP
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK---GGLATPP- 1167
Query: 235 PEPSPWAPCLLLGPGNLGGLLHWE-------------RLLGGLGGEEDTGRPWGPSRGPP 281
P+ +P P P GGL GGL G P P+ PP
Sbjct: 1168 PKGAPTTPA-ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226
Query: 282 QAQG--TSSGPNCAPGSSSSSSSDEAG-----DPNEAPSPDTLLGALARRQLNLGQLLED 334
+G + P AP + +++ G P AP+P A L G
Sbjct: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP----AATPPSLKGGLATPP 1282
Query: 335 TESYLQAFLAGAAGPLNGDHPGP--GQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPG 392
+ + P G P G + P PP S G P G TP A P
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK-GAPTPPAVTP- 1340
Query: 393 FGATSEGQGPLPFLSMFMGAGDAPLGSR--PGHPHSSSQVKSKLQIGPPSPGEAQGPLLP 450
+ +G LP + G S+ P P ++ K + PPSP +GP +P
Sbjct: 1341 --PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP--KRGPAIP 1396
Query: 451 SPARGLKFLKLPPTSEKSPSPGGPQLSPQLP---RNSRIPCRNSGSDGSPSPLLARRGLG 507
SP K PTS + P P+ +P P + P + + + +P+ ++
Sbjct: 1397 SP-------KGDPTS-PAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448
Query: 508 -----GGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPG------------- 549
GG +P ++G PT P+ TP S + P ++T+ SP
Sbjct: 1449 TSAPKGGPATP-SSKGDPTLPA---VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT 1504
Query: 550 -PVVSPCYENILDLSRSTFRGP--------SPEPPP--SPLQVPTYPQLTL----EVPQA 594
P V P + + S+ R P S + P +P + P +T+ + P
Sbjct: 1505 LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAI 1564
Query: 595 PEVLRSPGVPPS------PCLPESYPYGSPQEKSL-------DKAGSESPHPGRRTPGNS 641
P +P P S P + S G+P K L + E+P P TP +
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624
Query: 642 SKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVP-ARPGTEKTRGPGK 700
K P+ + + G P S P+ ++L T P VP A G +GP
Sbjct: 1625 EKGPATPAPK--GTPTSPPVTP--SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA 1680
Query: 701 SGE----SAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHS 756
E A + P I P + T P + DP A+ S
Sbjct: 1681 LKEVLVAPAPESTPIITAPTRK-----------GPQTKKSSATSPPICPDPSAKNGSKGP 1729
Query: 757 MG--ARVDLEPVSPRSCLT-KVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHS 813
+ A L PV S T K + A G L P P + A P +A + K P S
Sbjct: 1730 LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAP--PESKASTPLTAAAFEKVLPKPES 1787
Query: 814 S--------PTKLP-SKSPTKVVP-----RPGAPLVTKESPKPDKGKG---------PPW 850
+ P LP + SP +P P +P + ESP PP
Sbjct: 1788 ASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPE 1847
Query: 851 ADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAE 908
G QS LV PT S G P + ++ V K + + E P E
Sbjct: 1848 PISGGVPFQSV-LVNMPTPKSAGIP--VPTPSAKQPVTKNNKGSGTESDSDESVPELE 1902
Score = 90.1 bits (222), Expect = 1e-17
Identities = 200/822 (24%), Positives = 267/822 (32%), Gaps = 121/822 (14%)
Query: 119 PLTP---LQPPSEPPASPSLSST----EGPAAPLPLGHCAGQREVCWEQQLR--PGGPGP 169
PL+P PP E P +PS+ + EGPA P P A ++ R P G
Sbjct: 872 PLSPKGVTLPPKETP-TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI 930
Query: 170 PAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATP---WRPPGQGPGSPEPIN 226
PA+P P P T P PATP W P P P
Sbjct: 931 PASPSPKGAPTPP---------------AATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975
Query: 227 GELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGT 286
G P+ P+P A GG G P P+ PP +G+
Sbjct: 976 GPATPSPKGAPTPPAATP-------------PSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022
Query: 287 SSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGA 346
P P +S+ A P+ SP L L GA
Sbjct: 1023 ---PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 347 AGPLNGDHPGP---GQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPL 403
P P P + SP AP + + PK GG G T P
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK----GGLATPPHKGAPTTPAATPPS 1135
Query: 404 PFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLL--PSPARGLKFLKL 461
P G P P P ++ PP G P PSP GL
Sbjct: 1136 P----KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL----- 1186
Query: 462 PPTSEKSPSP-GGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLP 520
+PSP G P P + + G+P+ A G L+ +G P
Sbjct: 1187 -----ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241
Query: 521 TSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRG---PSPEPPPS 577
T+P+ +P PP T P P + L+ +G P+ PPS
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPT---PPAATPPSLKG--GLATPPHKGAPNPAVVTPPS 1296
Query: 578 PLQVP-TYPQLTLEVPQA---PEVLRSPGVPP---SPCLPESYPYGSPQEKSLDKAGSES 630
P P T P P A P SPG PP +P P P SP+ A + S
Sbjct: 1297 PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP-PSPKGTPTLPATTPS 1355
Query: 631 PHPGRRTPGN-SSKKPSQGSGRRPGDPGST-PLRDRLAALGKLKTGP--EGALGSEKNGV 686
G TP + P + G P T P R A+ K P +
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415
Query: 687 PARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEA------KGGIRGAVALGTNSLKQQE 740
PA P T + G + S GD+ P P+ +A KGG + G +L
Sbjct: 1416 PATPVTRE----GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 741 PGLMGDPGA--RVYSSHS----------MGARV--DLEPVSPRSCLTKVELAKSRLAGAL 786
P +P A +V +S S MGA + P SP+ + +A
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
Query: 787 CPQVPRTPAKVPTS------APSLGKPNKSPH-SSPTKLPSKSPTKVVPRPGA--PLVTK 837
+TPA + A ++ P K+P +P + P+ +K P A P K
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591
Query: 838 ESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAP 879
+P P + PP S TP P P +GP AP
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633
Score = 79.7 bits (195), Expect = 2e-14
Identities = 226/941 (24%), Positives = 309/941 (32%), Gaps = 151/941 (16%)
Query: 419 SRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSP 478
S P P S +K +G P P + SP + + K+ S GP +
Sbjct: 578 SSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG----VNSSASVIKTDSYAGPDSAG 633
Query: 479 QLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCY--TTPDSTQLR 536
L ++S I + PL + G + +G T+ SP T + +
Sbjct: 634 PLLKSSLIT-----PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNH 688
Query: 537 PPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPE 596
P + TTL P+V EN PSP+ +PL + APE
Sbjct: 689 PVKEGTLTTL---PLVPTASENCPV-------APSPQNTCAPLAT---------LVLAPE 729
Query: 597 VLRSPGVPPSPCLPESYPYGSPQ-EKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGD 655
+ +S PSP LP P G+P K +D H P SS K D
Sbjct: 730 IPKSV---PSPSLP---PAGTPPGTKKVDGIS----HTSALAPVASSPKECPTE-----D 774
Query: 656 PGSTPLRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDM-VPSIHR 714
G++ L L P GV P T+ R P K G + D + ++
Sbjct: 775 SGASATASSKGTLTYLADSPSPL------GVSVSPQTK--RPPTKKGSAGPDTPIGNLSS 826
Query: 715 PLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHS------MGARVD--LEPV 766
P+ +EA L NSL Q G P ++HS GA + P+
Sbjct: 827 PVSPVEAS-------FLPENSLSFQ--GSKDSPA----TTHSPTPPSPKGAPTPSAVTPL 873
Query: 767 SPRSC-LTKVELAKSRLAGALCPQV-PRTPAKVPTSAPSLGKPNKSPHSS-----PTKLP 819
SP+ L E + P+ P TPA P AP+L + SP + P +P
Sbjct: 874 SPKGVTLPPKETPTPSVVNLPFPKEGPATPA--PKQAPALSMTSSSPKKARATPAPKGIP 931
Query: 820 SKSPTKVVPRPGAPLVTKESPKPDKGK-GPPWADCGSTTAQSTPLVP--GPTDPSQGPEG 876
+ K P P P T SPK P WA T +TP P GP PS P+G
Sbjct: 932 ASPSPKGAPTP--PAATPPSPKGGPATPSPKWAP---TPPAATPPSPKGGPATPS--PKG 984
Query: 877 LAPHSAIEEKVMKGIEENVLRLQGQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTE 936
A KG +G P S A+ F S PA +
Sbjct: 985 APTPPAATPPSPKGGPATPSP-KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043
Query: 937 ATKNKEGAGGGSPLRREVKMEARKLEAESLNISKLMAKAEDLRRALEEEKAYLSSR---- 992
GSP + A A +L K L+ A A S
Sbjct: 1044 K---------GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
Query: 993 ARPRP-GGPAPGPNTGLGQVQGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYG 1051
A P P G P P T G ++GA T P P P+
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT------TPAATPPSPKGGLATPPPKGA 1148
Query: 1052 DFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSH 1111
P ++ P P+ GL P PP + P P + LA P P
Sbjct: 1149 PTTPAATPPS-------PKGGLATP------PPKGAPTTPAATPPSP-KGGLATPSPKGA 1194
Query: 1112 FTACGSLTRTLDSGIGT------------FPPPDHGSSGTPSKNLPKTKPPRLDPPPGVP 1159
T + + G+ T PP G TPS T P P P
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254
Query: 1160 PARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPC 1219
PA PPP A T P ++ L + H P + P +P + P
Sbjct: 1255 PATPPPKGAPTPPAAT----PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
Query: 1220 EDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEP-SR 1278
P TPP T P G+ + P + PP +G P P P + P S+
Sbjct: 1311 TPPAATPPSPKGSPGTPP---PKGAPTPPAVTPPSP-KGTPTLPATTPSSKGGPTTPSSK 1366
Query: 1279 PSPTPQGPPFGGSRTPSTSDMAEEGRVASGGPPGLETSESL 1319
PTP P+ + + + A P G TS ++
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407
Score = 77.8 bits (190), Expect = 6e-14
Identities = 215/961 (22%), Positives = 302/961 (31%), Gaps = 173/961 (18%)
Query: 423 HPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPR 482
H + + S+ + PP P + PA F + P+ +K PS
Sbjct: 343 HSSTGASYPSQRSVIPPLPSRNE----VVPATVAAFPVVAPSVDKGPST----------- 387
Query: 483 NSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSAL 542
S I C SGS + LSP + L +SP+ Y P Q+ P S++
Sbjct: 388 ISSITCSPSGSLNVATSF---------SLSPTTSLILKSSPNATYHYPLVAQM--PVSSV 436
Query: 543 STTLSPGPVVSPCYENILDLSRSTFRGPSPEPPP---SPLQ--VPTYPQLTLEVPQAPE- 596
TT P V +PC I +TF + PP P+ PT P + P AP+
Sbjct: 437 GTT--PLVVTNPC--TIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKE 492
Query: 597 -------VLRSPGVPPSPC------LPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSK 643
LR P PP P LP S P +K L + +
Sbjct: 493 PSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLE--------GAPF 544
Query: 644 KPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGE 703
P+Q DP PL K P S +P P + +
Sbjct: 545 SPAQAGLTTKKDPTVLPLVQAAP-----KNSPSFQSTSSSPEIPLSPEATLAK------K 593
Query: 704 SAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDL 763
S G+ +P I +P + + LG NS A V + S
Sbjct: 594 SLGEPLP-IGKPASSMTSP--------LGVNS------------SASVIKTDSYAGPDSA 632
Query: 764 EPVSPRSCLTKV----ELAKSRLAGALCPQVPRTPAKVPTSAPSL-GKPNKSPHSSPTKL 818
P+ S +T L + AG T T++P L G + +P + P K
Sbjct: 633 GPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKE 692
Query: 819 PSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLA 878
+ + +VP SP+ +T A LV P P P
Sbjct: 693 GTLTTLPLVPTASENCPVAPSPQ-------------NTCAPLATLVLAPEIPKSVPSPSL 739
Query: 879 PHSAIEE--KVMKGIEENVLRLQGQERAPGAEVKHRNTSSIASWFG----LKKSKLP--- 929
P + K + GI + S+ AS G L S P
Sbjct: 740 PPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGV 799
Query: 930 ALNRRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNISKLMAKAEDLRRALEEEKAYL 989
+++ +T+ K+G+ G + +EA L + L + ++ A
Sbjct: 800 SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS------KDSPATT 853
Query: 990 SSRARPRP-GGPAPGPNTGLGQVQGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKP 1048
S P P G P P T L L +T ++N KE P+ + P
Sbjct: 854 HSPTPPSPKGAPTPSAVTPLSPKGVTLPPK----ETPTPSVVNLPFPKEGPATPAPKQAP 909
Query: 1049 EYGDFQPVSSDPKSPWPACGPRNGLVGPL-QGCGKPPGKPSSEPGRREEMPSEDSLAEPV 1107
SS PK P+ P +G PP P PS P
Sbjct: 910 A---LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
Query: 1108 PTSHFTACGSLTRTLDSGIGT----FPPPDHGSSGTPSKNLPKTKPPRLDPPP------- 1156
+ + G G T PP G TPS T P P P
Sbjct: 967 AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
Query: 1157 ------GVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRG 1210
PPA PP K A L + P + PS P PA P +G
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL----PS----PKGGPATPSLKG 1078
Query: 1211 HETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDR 1270
T P P P K P S L PP + G P TP A P
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHK--GAPTTPAATPPSP 1136
Query: 1271 KRS----------QEPSRPSPTPQG-----PPFGGSRTPSTSDMAEEGRVASGGPPGLET 1315
K P+ P+P+G PP G TP+ + + +G +A+ P G T
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196
Query: 1316 S 1316
+
Sbjct: 1197 T 1197
Score = 50.8 bits (120), Expect = 8e-06
Identities = 113/490 (23%), Positives = 165/490 (33%), Gaps = 93/490 (18%)
Query: 114 SLPQI-PLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGP-PA 171
+LP + P +P +PP+ + S S + PA P P+G + P P PA
Sbjct: 1466 TLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI-------PSSPKEVPA 1518
Query: 172 APPPALDALSP---FLRKKAQIL----EVLRALEETDPLLLCSPATPWRPPGQGPGSPEP 224
P D ++P L KK E L T P +PA P P + P +P
Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIP--TPKEAPATPS- 1575
Query: 225 INGELCGPPQPEPSPW----APCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGP 280
+ E PP PS + +P LL P + E P P +GP
Sbjct: 1576 -SKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE------APTPPAVTPPSPEKGP 1628
Query: 281 --PQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESY 338
P +GT + P P S S P S +GA Q + G + +
Sbjct: 1629 ATPAPKGTPTSPPVTPSSLKDS-------PTSPASVTCKMGATV-PQASKGLPAKKGPTA 1680
Query: 339 LQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSE 398
L+ L A P+ P + ++ P++ T P A +
Sbjct: 1681 LKEVLVAPA---------------PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNG 1725
Query: 399 GQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSK----LQIGPPSPGEAQGPLLPSPAR 454
+GPL + AP P SS K K GP +P E++ + A
Sbjct: 1726 SKGPLSTV--------APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
Query: 455 GLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPE 514
K L P ++ S +P P P P SP P L P
Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAP--------------SPVPTL-----------PP 1812
Query: 515 GAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPC-YENILDLSRSTFRGPSPE 573
Q LP+SP +P + L + P P+ ++++L + P
Sbjct: 1813 KQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPV 1872
Query: 574 PPPSPLQVPT 583
P PS Q T
Sbjct: 1873 PTPSAKQPVT 1882
Score = 43.9 bits (102), Expect = 0.001
Identities = 67/270 (24%), Positives = 83/270 (30%), Gaps = 49/270 (18%)
Query: 1060 PKSPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRRE--EMPSEDSLAEPVPTSHFTACGS 1117
P P P P + V PL P K + P RE PS+ L P T
Sbjct: 1393 PAIPSPKGDPTSPAVIPLS-----PKKAPATPVTREGAATPSKGDLTPPAVTPV------ 1441
Query: 1118 LTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPA----------RPPPLT 1167
+L T P G TPS T P P P PPA + P T
Sbjct: 1442 ---SLKKAPATSAPK--GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496
Query: 1168 KVPRRAHTLEREVPG----IEELLVSGRHPSMPAFP--------------ALLPAAPGHR 1209
P A TL +P + S R P P AL+P A
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556
Query: 1210 GHETCPDDPCEDPGPTPPVQLAKNW---TFPNTRAAGSSSDPLMCPPRQLEGLPRTPMAL 1266
+ P P P P + P+T S L+ PP P+
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616
Query: 1267 PVDRKRSQEPSRPSPTPQGPPFGGSRTPST 1296
P S E +P P+G P TPS+
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646
Score = 42.7 bits (99), Expect = 0.002
Identities = 108/448 (24%), Positives = 152/448 (33%), Gaps = 76/448 (16%)
Query: 446 GPLLPSPARGL-KFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARR 504
GP LP P + L ++ SP P P P P S G+ PL
Sbjct: 42 GPTLPPPCSPAPQQCPLSAANQASPFPS-PSTIASTPLEVPFP---QSSSGTALPL---- 93
Query: 505 GLGGGELSPEGAQGLPTSP-SPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLS 563
G +P L P SP S + P ++ +P +V+ ++
Sbjct: 94 --GTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQ--K 149
Query: 564 RSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAP------------EVLRSP-GVPPSPCLP 610
S F PPS + +TL P AP EV+ +P G P PC+
Sbjct: 150 SSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIV 209
Query: 611 ESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGR------RPGDPGSTPLRDR 664
+ PY + ++G S T + P P +PGS L+
Sbjct: 210 STVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGP 269
Query: 665 LAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGE---SAGDMVPSIHRPLEQLEA 721
++ P AL +P ++KT GP + S G + +H+
Sbjct: 270 VS--------PPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQ------- 314
Query: 722 KGGIRGAVALGTNSLKQQEPGLMGDPGARVYS--SHSMGARVDLEPVSPRSCLTKVELAK 779
G+V L L Q P + DP + S S GA S RS + +
Sbjct: 315 --SSFGSVQL----LGQTGPSALSDPTVKTISVDHSSTGASYP----SQRSVIPPLPSRN 364
Query: 780 SRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKS---PTKVVPRPGAPLVT 836
VP T A P APS+ K S SS T PS S T P L+
Sbjct: 365 E--------VVPATVAAFPVVAPSVDK-GPSTISSITCSPSGSLNVATSFSLSPTTSLIL 415
Query: 837 KESPKPDKGKGPPWADCGSTTAQSTPLV 864
K SP P A ++ +TPLV
Sbjct: 416 KSSPNATY-HYPLVAQMPVSSVGTTPLV 442
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 89.0 bits (219), Expect = 3e-17
Identities = 229/875 (26%), Positives = 287/875 (32%), Gaps = 201/875 (22%)
Query: 115 LPQIPLTPLQPP-SEPPASPSLSSTEGPAAPL----PLGHCAGQ-REVCWEQQLRPGGPG 168
+P+ P+ P SE P + EGP P G R+ Q PG PG
Sbjct: 86 VPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPG 145
Query: 169 PPAAP-PPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPG--QGPGSPEPI 225
PP P PP L A L + T + + P P P G PG+P P
Sbjct: 146 PPGPPGPPGLGG------NFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQ 199
Query: 226 NGELCGPP-QP-EPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGP-SRGPPQ 282
+ GPP +P EP P +GP G G G + + G+P P RGPP
Sbjct: 200 GFQ--GPPGEPGEPGASGP---MGPRGPPG------PPGKNGDDGEAGKPGRPGERGPPG 248
Query: 283 AQGTSSGPNCA--PGSSS----SSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTE 336
QG P A PG S GD
Sbjct: 249 PQGARGLPGTAGLPGMKGHRGFSGLDGAKGD----------------------------- 279
Query: 337 SYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQ-LSKSKGLPKSAWGGGTPEAHRPGFGA 395
AG AGP G+ PG++ +P Q P+ L +G P G P R GA
Sbjct: 280 -------AGPAGP-KGEPGSPGENGAPGQMGPRGLPGERGRP----GAPGPAGARGNDGA 327
Query: 396 TSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARG 455
T P P P G PG P V +K + GP P ++G P RG
Sbjct: 328 TGAAGPPGP---------TGPAGP-PGFP---GAVGAKGEAGPQGPRGSEG---PQGVRG 371
Query: 456 LKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLAR--RGLGG----- 508
P P G P + P N G+DG P A G+ G
Sbjct: 372 ------------EPGPPG-------PAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412
Query: 509 GELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTL--SPGPV-----VSPCYENILD 561
G P G QG P P +S + P S T PGPV P E
Sbjct: 413 GARGPSGPQGPGGPPGP---KGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE---- 465
Query: 562 LSRSTFRGPSPEPPPSPLQVPT----------YPQLT-LEVPQAPEVLRSPGVPPSPCLP 610
RG EP P+ L P +P + P+ P R P P P
Sbjct: 466 ---EGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERG---SPGPAGP 519
Query: 611 ESYP--YGSPQEKSLDKAGSESPHPGRRTPGNSSKKPS-QGSGRRPGDPGSTPLRDRLAA 667
+ P G P E L A + PG P + P G RPG PG R +
Sbjct: 520 KGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGV 579
Query: 668 LGKLKTGPEGALG----SEKNGVPARPGTEKTRGP-GKSGESAGDMVPSIHRPLEQLEAK 722
+G GP+GA G + + GVP PG GP GK GE+ P P + +
Sbjct: 580 MG--FPGPKGAAGEPGKAGERGVPGPPGAV---GPAGKDGEAGAQGPPGPAGPAGERGEQ 634
Query: 723 G--------GIRGAVALGTNSLKQQEPGLMGDPGARVYSS--------HSMGARVDLEPV 766
G G+ G + K E G+ GD GA S G + P
Sbjct: 635 GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPA 694
Query: 767 SPRSC--LTKVELAKSRLAGALCPQVPRTPA--KVPTSAPSLGKPN----------KSPH 812
PR + AK P P +P + G P K
Sbjct: 695 GPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGAD 754
Query: 813 SSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQ 872
SP K + T + PG DKG+ P G T A+ P G P
Sbjct: 755 GSPGKDGVRGLTGPIGPPG-----PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGP-P 808
Query: 873 GPEGLA-PHSAIEEKVMKGIEENVLRLQGQERAPG 906
GP G A P A + KG E +G PG
Sbjct: 809 GPAGFAGPPGADGQPGAKG-EPGDAGAKGDAGPPG 842
Score = 86.3 bits (212), Expect = 2e-16
Identities = 227/928 (24%), Positives = 293/928 (31%), Gaps = 215/928 (23%)
Query: 116 PQIPLTPLQP-PSEPPA-----SPSLS------STEGPAAPLPLGHCAGQREVCWEQQLR 163
P +P P P P PP +P LS ST G + P P+G +G R
Sbjct: 138 PGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGP-SGPR--------- 187
Query: 164 PGGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQG----- 218
G PGPP AP P F + E + P+ P P PPG+
Sbjct: 188 -GLPGPPGAPGP-----QGFQGPPGEPGEP----GASGPM---GPRGPPGPPGKNGDDGE 234
Query: 219 ---PGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWG 275
PG P GE GPP P+ + P PG G R GL G + P G
Sbjct: 235 AGKPGRP----GER-GPPGPQGARGLPGTAGLPGMKG-----HRGFSGLDGAKGDAGPAG 284
Query: 276 PS-----------------RGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEA--PSPDT 316
P RG P +G P A + ++ AG P P
Sbjct: 285 PKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG 344
Query: 317 LLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAP-----PQLS 371
GA+ + Q +E + G GP PGP ++ P P P
Sbjct: 345 FPGAVGAKGEAGPQGPRGSEG--PQGVRGEPGP-----PGPAGAAGPAGNPGADGQPGAK 397
Query: 372 KSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGS--RPGHPHSSSQ 429
+ G P A G P A P S QGP G P G+ PG P S
Sbjct: 398 GANGAPGIAGAPGFPGARGP-----SGPQGP--------GGPPGPKGNSGEPGAPGSKGD 444
Query: 430 VKSKLQIGP------PSPGEAQGPL----------LPSP--------------ARGLKFL 459
+K + GP P P +G LP P A G+
Sbjct: 445 TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGP 504
Query: 460 KLPPTSEKSPSPGGPQLSPQ---LPRNSRIPCRN--SGSDGSPSPLLARRGLGGGELSPE 514
K P SP P GP+ SP P + +P +GS GSP P + G G P
Sbjct: 505 KGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPD-GKTGPPG----PA 559
Query: 515 GAQGLPTSPSPC----------YTTPDSTQLRPPQSALSTTLSPGPVVSPCYEN------ 558
G G P P P + P P ++ P V P ++
Sbjct: 560 GQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ 619
Query: 559 -----ILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVP-PSPCLPES 612
+GP+ P L P P P V G P PS E
Sbjct: 620 GPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGER 679
Query: 613 YPYGSPQEKSLD-KAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKL 671
G P E+ + G P PGN K G+ PG G+ L+ G
Sbjct: 680 ---GFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAA 736
Query: 672 -KTGPEGALG-SEKNGVPARPGTEKTRG-------------PGKSGES--AGDMVPSIHR 714
GP+G G + G PG + RG PG GES +G P+ R
Sbjct: 737 GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGAR 796
Query: 715 PLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTK 774
+ G G +PG G+PG GA+ D P P
Sbjct: 797 GAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG-------DAGAKGDAGPPGPAGPAGP 849
Query: 775 V----ELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPS---------- 820
+ GA P P +A +G P S ++ P P
Sbjct: 850 PGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGP 909
Query: 821 KSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPH 880
+ T RPG + P P KG P AD G A TP GP+G+A
Sbjct: 910 RGETGPAGRPG-EVGPPGPPGPAGEKGSPGAD-GPAGAPGTP----------GPQGIAGQ 957
Query: 881 SAIEEKVMKGIEENVLRLQGQERAPGAE 908
+ + E L G PG +
Sbjct: 958 RGVVGLPGQRGERGFPGLPGPSGEPGKQ 985
Score = 71.2 bits (173), Expect = 6e-12
Identities = 209/816 (25%), Positives = 258/816 (31%), Gaps = 154/816 (18%)
Query: 116 PQIPLTPLQPPS------EPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRP--GGP 167
P P P PP EP A S T P P+G G E+ R G P
Sbjct: 417 PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVG-VQGPPGPAGEEGKRGARGEP 475
Query: 168 GPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQ----GPGSPE 223
GP P P + P R D + A P P G+ GP P+
Sbjct: 476 GPTGLPGPPGERGGPGSR----------GFPGADGV-----AGPKGPAGERGSPGPAGPK 520
Query: 224 PINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQA 283
GE G P P A L PG+ G + G G GRP P GPP A
Sbjct: 521 GSPGE-AGRPGEAGLPGAKGLTGSPGSPGP----DGKTGPPGPAGQDGRPGPP--GPPGA 573
Query: 284 QGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFL 343
+G +G PG ++ P P +G + D E+ Q
Sbjct: 574 RG-QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGK----------DGEAGAQG-P 621
Query: 344 AGAAGPLN-----GDHPGPGQSSSPDQAPPQLSKSK----GLPKSAWGGGTPEAH-RPGF 393
G AGP G PG P A P K G+P G A GF
Sbjct: 622 PGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGF 681
Query: 394 GATSEGQGPLPFLSMFMGAGDAPLGS-------RPGHPHSSSQVKSKLQIGPPSPGEAQG 446
QGP P + GA AP PG P SQ LQ PGE
Sbjct: 682 PGERGVQGP-PGPAGPRGANGAPGNDGAKGDAGAPGAP--GSQGAPGLQ---GMPGERGA 735
Query: 447 PLLPSPARGLKFLKLPPTSEKSPSPGGPQ-----LSPQLPRNSRIPCRNSGSDGSPSPLL 501
LP P +G + P ++ SP G + + P P + SG G P
Sbjct: 736 AGLPGP-KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTG 794
Query: 502 ARRGLG----------GGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPV 551
AR G G P GA G P + PP A PGP+
Sbjct: 795 ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA-GPAGPPGPI 853
Query: 552 VSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEV-PQAPEVLRSPGVPPSPCLP 610
N+ RG + P + +P V P P P PP P
Sbjct: 854 -----GNVGAPGAKGARGSAGPPGATG-----FPGAAGRVGPPGPSGNAGPPGPPGPAGK 903
Query: 611 ESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGK 670
E + + G P PG PG + +K S G+ G PG TP
Sbjct: 904 EGGKGPRGETGPAGRPGEVGP-PG--PPGPAGEKGSPGADGPAGAPG-TP---------- 949
Query: 671 LKTGPEGALGSEKNGVPARPGTEKTRG----PGKSGESAGDMVPSIHRPLEQLEAKGGIR 726
GP+G G + GV PG RG PG SGE G PS G
Sbjct: 950 ---GPQGIAG--QRGVVGLPGQRGERGFPGLPGPSGEP-GKQGPSGASGERGPPGPMGPP 1003
Query: 727 GAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGAL 786
G S ++ PG G PG R S + G R + P P
Sbjct: 1004 GLAGPPGESGREGAPGAEGSPG-RDGSPGAKGDRGETGPAGPPGA--------------- 1047
Query: 787 CPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPR-PGAPLVTKESPKPDKG 845
P P P V + S + P P+ V R P P + P+ DKG
Sbjct: 1048 -PGAPGAPGPVGPAGKSGDRGETGPAG-----PAGPVGPVGARGPAGP----QGPRGDKG 1097
Query: 846 KGPPWADCGSTTAQSTPLVPGPTDP-----SQGPEG 876
+ D G + + GP P QGP G
Sbjct: 1098 ETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSG 1133
Score = 47.4 bits (111), Expect = 9e-05
Identities = 107/419 (25%), Positives = 121/419 (28%), Gaps = 114/419 (27%)
Query: 129 PPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDALSPFLRKKA 188
PP P + EG P AG RPG GPP P PA + SP A
Sbjct: 894 PPGPPGPAGKEGGKGPRGETGPAG----------RPGEVGPPGPPGPAGEKGSPGADGPA 943
Query: 189 QILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPPQPEPSPWAPCLLLGP 248
P P QG + G L G P P P
Sbjct: 944 --------------------GAPGTPGPQGIAGQRGVVG-LPGQRGERGFPGLPGPSGEP 982
Query: 249 GNLGGLLHWERLLGGLGGEEDTGRPWGPS--RGPPQAQGTSSGPNCAPGSSSSSSSDEAG 306
G G G GE P GP GPP G P S G
Sbjct: 983 GKQGP--------SGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKG 1034
Query: 307 DPNEA--PSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGP-GQSSSP 363
D E P GA GA GP+ GP G+S
Sbjct: 1035 DRGETGPAGPPGAPGA-----------------------PGAPGPV-----GPAGKSGDR 1066
Query: 364 DQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGH 423
+ P P A G P+ R G T E GD + G
Sbjct: 1067 GETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGE-------------QGDRGIKGHRGF 1113
Query: 424 PHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRN 483
S LQ GPP P + G PS A G + PP S +P G P
Sbjct: 1114 --------SGLQ-GPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLP----- 1159
Query: 484 SRIPCRNSGSDGSPSPLLARRGLGG--GELSPEGAQGLPTSPSPCYTTPDSTQL-RPPQ 539
G G P P RG G G + P G G P P P D + L +PPQ
Sbjct: 1160 --------GPIGPPGP----RGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQ 1206
Score = 39.3 bits (90), Expect = 0.026
Identities = 48/190 (25%), Positives = 66/190 (34%), Gaps = 23/190 (12%)
Query: 1141 SKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPA 1200
+KN P + P + P P P ++E G+E P P PA
Sbjct: 78 TKNCPGAEVPEGECCPVCPDGSESPT----------DQETTGVEGPK-GDTGPRGPRGPA 126
Query: 1201 LLPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNWTFP-----NTRAAGSSSDPLMCPPRQ 1255
P G G P P PGP P L N+ + ++ G S P P
Sbjct: 127 GPPGRDGIPGQPGLPGPP-GPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSG 185
Query: 1256 LEGLPRTPMALPVDRKRSQ--EPSRPSPT----PQGPPFGGSRTPSTSDMAEEGRVASGG 1309
GLP P A + EP P + P+GPP + + + GR G
Sbjct: 186 PRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERG 245
Query: 1310 PPGLETSESL 1319
PPG + + L
Sbjct: 246 PPGPQGARGL 255
Score = 37.7 bits (86), Expect = 0.074
Identities = 91/362 (25%), Positives = 115/362 (31%), Gaps = 64/362 (17%)
Query: 995 PRPGGPAPGPNTGLGQVQGQLAGMYQGADT---FMQQLLNRVDGKELPS-------KSWR 1044
P P GP PGP G QL+ Y T + + + LP + ++
Sbjct: 144 PGPPGP-PGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQ 202
Query: 1045 EPKPEYGDFQPVSSDPKSPWPACGP--RNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDS 1102
P E G+ P +S P P GP +NG G G+P + P +P
Sbjct: 203 GPPGEPGE--PGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAG 260
Query: 1103 LAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKN-LPKTKPPRLDPPPGVPPA 1161
L P H G D+G P G G+P +N P PR P P
Sbjct: 261 L--PGMKGHRGFSGLDGAKGDAG----PAGPKGEPGSPGENGAPGQMGPRGLPGERGRPG 314
Query: 1162 RPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCE- 1220
P P T PG P+ PA P P A G +G E P P
Sbjct: 315 APGPAGARGNDGATGAAGPPG----------PTGPAGPPGFPGAVGAKG-EAGPQGPRGS 363
Query: 1221 --------DPGPTPPVQLAKNWTFPNTR----AAGSSSDPLMCPPRQLEGL-----PRTP 1263
+PGP P A P A G++ P + G P+ P
Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423
Query: 1264 MALPVDRKRSQEPSRPS----------PTP---QGPPFGGSRTPSTSDMAEEGRVASGGP 1310
P + S EP P P P QGPP E G GP
Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483
Query: 1311 PG 1312
PG
Sbjct: 484 PG 485
Score = 31.6 bits (70), Expect = 5.3
Identities = 66/275 (24%), Positives = 85/275 (30%), Gaps = 37/275 (13%)
Query: 1060 PKSPWPACGPRN----GLVGPLQGCGK--PPGKPSSEPGRREEMPS--------EDSLAE 1105
P +P PA N G GP G PPG P + + E P + E
Sbjct: 313 PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGE 372
Query: 1106 PVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTP----SKNLPKTKPPRLDPPPGVPPA 1161
P P A G G P G++G P + P + P PG PP
Sbjct: 373 PGPPGPAGAAGPAGNPGADG----QPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG 428
Query: 1162 RPPPLTKVP----RRAHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDD 1217
P + P + T + PG V + P PA A G G P
Sbjct: 429 -PKGNSGEPGAPGSKGDTGAKGEPGP----VGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483
Query: 1218 PCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPS 1277
P E GP + AG P P+ G P + + S
Sbjct: 484 PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGS 543
Query: 1278 RPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGPPG 1312
SP P G +T ++GR GPPG
Sbjct: 544 PGSPGPDG------KTGPPGPAGQDGRPGPPGPPG 572
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 87.4 bits (215), Expect = 8e-17
Identities = 188/688 (27%), Positives = 230/688 (33%), Gaps = 152/688 (22%)
Query: 126 PSEPPASPSLSSTEGP----AAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDALS 181
PS P P + GP AP G G PGGPGP PP +
Sbjct: 568 PSGPRGQPGVMGFPGPKGNDGAPGKNGERGG-----------PGGPGPQG--PPGKNG-- 612
Query: 182 PFLRKKAQILEVLRALEETDPLLLCSPATP------WRPPG-------QGPGSPEPINGE 228
ET P P P PPG G G P NG+
Sbjct: 613 -----------------ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGK 655
Query: 229 LCGPPQPEPSPWAPCLLLGPGNLG--------GLLHWERLLGGLG--GEEDTGRPWGPSR 278
G P P+ AP G G+ G GL L GG G G E GP
Sbjct: 656 -PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPP- 713
Query: 279 GPPQAQGT---SSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLN-------- 327
GPP A GT P G S + G+P P D + G R
Sbjct: 714 GPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPG-GPGADGVPGKDGPRGPTGPIGPPGP 772
Query: 328 LGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLP-KSAWGGGTP 386
GQ + E L G AGP PG+ + PP + G P ++ GG
Sbjct: 773 AGQPGDKGEGGAPG-LPGIAGP----RGSPGERG--ETGPPGPAGFPGAPGQNGEPGGKG 825
Query: 387 EAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQG 446
E PG +G+G P G P GS P P VK + + P PG A
Sbjct: 826 ERGAPG----EKGEGGPP------GVAGPPGGSGPAGPPGPQGVKGE-RGSPGGPGAAGF 874
Query: 447 PLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGL 506
P G + L PP S +P P GP SP P N+G+ GSP + +G
Sbjct: 875 P-------GARGLPGPPGSNGNPGPPGPSGSPG-KDGPPGPAGNTGAPGSPG-VSGPKGD 925
Query: 507 GG--GELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSR 564
G GE GAQG P +P P + + PGP SP + +
Sbjct: 926 AGQPGEKGSPGAQGPPGAPGPL----GIAGITGARGLAGPPGMPGPRGSPGPQGV----- 976
Query: 565 STFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSP---GVPPSPCLPESYPYGSPQEK 621
+G S +P + L P +P P G P S LP GSP K
Sbjct: 977 ---KGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGR--DGSPGGK 1031
Query: 622 SLDKAGSESP-------HPGRRTP----GNSSKKPSQGSGRRPGDPGSTPLRDRLAALG- 669
D+ + SP HPG P G S + G G PG R G
Sbjct: 1032 G-DRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGP 1090
Query: 670 ---KLKTGPEGALGSE-KNGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAKGGI 725
K +TG GA G + G P PG + GP + G P+ G
Sbjct: 1091 RGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPA------------GP 1138
Query: 726 RGAVALGTNSLK---QQEPGLMGDPGAR 750
RG V K PG +G PG R
Sbjct: 1139 RGPVGPSGPPGKDGTSGHPGPIGPPGPR 1166
Score = 80.1 bits (196), Expect = 1e-14
Identities = 193/738 (26%), Positives = 242/738 (32%), Gaps = 132/738 (17%)
Query: 165 GGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEP 224
G PGPP P A SP K ++ P P QGP P
Sbjct: 330 GQPGPPGPPGTAGFPGSP--GAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPG 387
Query: 225 INGELCGPPQPEPS--PWAPCLL--LGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGP 280
ING G + P+ P AP L+ GP G L GG G G P GP
Sbjct: 388 INGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEP--GP 445
Query: 281 PQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQ 340
+G + P PG+ D G P E P + L GA R
Sbjct: 446 RGERGEAGIPG-VPGAKGEDGKD--GSPGE-PGANGLPGAAGERGA-------------- 487
Query: 341 AFLAGAAGP--LNGDHPGPGQSSSPDQAPPQLSKSK----GLPKSAWGGGTPEAHRPGFG 394
G AGP + G+ G+ +P A P+ + + G+P G P + PG G
Sbjct: 488 PGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGS--PG-G 544
Query: 395 ATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPAR 454
S+G+ P G RPG P S +G P P G + R
Sbjct: 545 PGSDGKPGPP--------GSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGER 596
Query: 455 GLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRN--SGSDGSPSPLLARRGLGG--GE 510
G PGGP PQ P P +N +G G P P G GG G+
Sbjct: 597 G--------------GPGGP--GPQGP-----PGKNGETGPQGPPGPT----GPGGDKGD 631
Query: 511 LSPEGAQGLPTSPSPCYTTPDSTQLRP----PQSALSTTLSPGPVVSPCYENILDLSRST 566
P G QGL P P +P P+ +PG +
Sbjct: 632 TGPPGPQGLQGLPGT--GGPPGENGKPGEPGPKGDAGAPGAPG-------------GKGD 676
Query: 567 FRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYP--YGSPQEKSLD 624
P PP P P PE + PP P P G P E+
Sbjct: 677 AGAPGERGPPGLAGAPGLRGGA--GPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERG-- 732
Query: 625 KAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSE-K 683
G +PG K G G PG R +G GP G G + +
Sbjct: 733 ---------GLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG--PPGPAGQPGDKGE 781
Query: 684 NGVPARPGTEKTRG-PGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPG 742
G P PG RG PG+ GE+ G P+ + G +G + PG
Sbjct: 782 GGAPGLPGIAGPRGSPGERGET-GPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPG 840
Query: 743 LMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAP 802
+ G PG S G P P+ K E GA R P S
Sbjct: 841 VAGPPG----GSGPAG------PPGPQG--VKGERGSPGGPGAAGFPGARGLPGPPGSNG 888
Query: 803 SLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTP 862
+ G P P SP K P PG+P V+ PK D G+ + GS AQ P
Sbjct: 889 NPGPP--GPSGSPGKDGPPGPAGNTGAPGSPGVS--GPKGDAGQP---GEKGSPGAQGPP 941
Query: 863 LVPGPTDPS--QGPEGLA 878
PGP + G GLA
Sbjct: 942 GAPGPLGIAGITGARGLA 959
Score = 75.9 bits (185), Expect = 2e-13
Identities = 269/1128 (23%), Positives = 331/1128 (29%), Gaps = 235/1128 (20%)
Query: 221 SPEPINGELCGP-PQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSR- 278
+PE GE C PQP +P P GP G + D G P P R
Sbjct: 76 NPEIPFGECCAVCPQPPTAPTRPPNGQGPQ---------------GPKGDPGPPGIPGRN 120
Query: 279 GPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESY 338
G P G P +PG S G N +P D+ D +S
Sbjct: 121 GDPGIPGQPGSPG-SPGPPGICESCPTGPQNYSPQYDSY----------------DVKSG 163
Query: 339 LQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSE 398
+ A G L G +PGP P PP S G P S G P PG S
Sbjct: 164 V------AVGGLAG-YPGPAGPPGPP-GPPGTSGHPGSPGSPGYQGPPG--EPGQAGPSG 213
Query: 399 GQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKF 458
GP + AG RPG P G P P +GP + G
Sbjct: 214 PPGPPGAIGPSGPAGKDGESGRPGRPGER---------GLPGPPGIKGP---AGIPGFPG 261
Query: 459 LKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQG 518
+K + G +P L + +P G +G+P P+ P GA G
Sbjct: 262 MKGHRGFDGRNGEKGETGAPGLKGENGLP----GENGAPGPM-----------GPRGAPG 306
Query: 519 LPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSP 578
P P + R A + PGP PP
Sbjct: 307 ERGRPG----LPGAAGARGNDGARGSDGQPGP----------------------PGPPGT 340
Query: 579 LQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTP 638
P P EV A G P S P PQ AG++ P
Sbjct: 341 AGFPGSPGAKGEVGPA-------GSPGSNGAPGQRGEPGPQ----GHAGAQGPPGPPGIN 389
Query: 639 GNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEK-NGVPARPGTEKTRG 697
G+ K G PG PG R GP GA G+ G PG +G
Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARG--------PPGPAGANGAPGLRGGAGEPGKNGAKG 441
Query: 698 -PGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHS 756
PG GE +P G+ GA EPG G PGA +
Sbjct: 442 EPGPRGERGEAGIP-------------GVPGAKGEDGKDGSPGEPGANGLPGA----AGE 484
Query: 757 MGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPT 816
GA P P + A R GA P PR A P G P
Sbjct: 485 RGAPGFRGPAGPNGIPGEKGPAGER--GAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSP 542
Query: 817 KLPSKSPTKVVPRPGAPLVTKES-----PKPDKGKGPPWADCGSTTAQSTPLVPGPTDPS 871
P +PG P ES P P +G P G + PG
Sbjct: 543 GGPGSDG-----KPGPPGSQGESGRPGPPGPSGPRGQPGV-MGFPGPKGNDGAPGKNGER 596
Query: 872 QGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAEVKHRNTSSIASWFGLKKSKLPAL 931
GP G P + G + PG + GL + P
Sbjct: 597 GGPGGPGPQGPPGKNGETGPQG-----PPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG 651
Query: 932 NRRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNISKLMAKAEDLRRALEEEKAYLSS 991
+G G+P K +A A +A A LR
Sbjct: 652 ENGKPGEPGPKG-DAGAPGAPGGKGDAG---APGERGPPGLAGAPGLRGGAGPPGPEGGK 707
Query: 992 RARPRPGGPAPGPNTGLGQVQGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYG 1051
A PG P GL + G+ G+ G P EP
Sbjct: 708 GAAGPPGPPGAAGTPGLQGMPGERGGL----------------GSPGPKGDKGEPGGPGA 751
Query: 1052 DFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREE--MPSEDSLAEPVPT 1109
D P P+ P GP+ PPG P+ +PG + E P +A P +
Sbjct: 752 DGVPGKDGPRGP----------TGPIG----PPG-PAGQPGDKGEGGAPGLPGIAGPRGS 796
Query: 1110 SHFTACGSLTRTLDSGIGTFP--------PPDHGSSGTPSKNLPKTKPPRLDPPPGVPPA 1161
G T G FP P G G P + P PP G PA
Sbjct: 797 P-----GERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPA 851
Query: 1162 RPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPAL--LPAAPGHRGHETCPDDPC 1219
PP V ER PG P FP LP PG G+ P P
Sbjct: 852 GPPGPQGVKG-----ERGSPG---------GPGAAGFPGARGLPGPPGSNGNPG-PPGPS 896
Query: 1220 EDPGPTPPVQLAKNWTFPNTRAA----GSSSDPLMCPPRQLEGLPRTPMALPV-----DR 1270
PG P A N P + G + P +G P P L + R
Sbjct: 897 GSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR 956
Query: 1271 KRSQEPSRP----SPTPQGPPFGGSRTPSTSDMA-EEGRVASGGPPGL 1313
+ P P SP PQG G S P + ++ E G G PGL
Sbjct: 957 GLAGPPGMPGPRGSPGPQGVK-GESGKPGANGLSGERGPPGPQGLPGL 1003
Score = 70.9 bits (172), Expect = 8e-12
Identities = 201/767 (26%), Positives = 247/767 (32%), Gaps = 188/767 (24%)
Query: 208 PATPWRPP-GQGP----GSPEP-----------INGELCGPPQPEPSPWAPCLLLGPGNL 251
P P RPP GQGP G P P I G+ P P P GP N
Sbjct: 92 PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNY 151
Query: 252 GGLLHWERLLGGL--GGEEDTGRPWGPSRGPPQAQGTSSGPNC--APGSSSSSSSDEAGD 307
+ G+ GG P GP GPP GTS P +PG
Sbjct: 152 SPQYDSYDVKSGVAVGGLAGYPGPAGPP-GPPGPPGTSGHPGSPGSPGYQGPPGEPGQAG 210
Query: 308 PNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAG-PLNGDHPGPGQSSSPDQA 366
P+ P P +G G +D ES G G P PGP P
Sbjct: 211 PSGPPGPPGAIGPS-------GPAGKDGES-------GRPGRPGERGLPGPPGIKGPAGI 256
Query: 367 P--PQLSKSKGLPKSAWGGGTPEAHRPGF----GATSEGQGPLPFLSMFMGAGDAP-LGS 419
P P + +G G E PG G E P P MG AP
Sbjct: 257 PGFPGMKGHRGF--DGRNGEKGETGAPGLKGENGLPGENGAPGP-----MGPRGAPGERG 309
Query: 420 RPGHPHSSSQVK------SKLQIGPPSP-GEAQGPLLPSPARGLKFLKLPPTSEKSPSPG 472
RPG P ++ S Q GPP P G A P P A+G P S +P
Sbjct: 310 RPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPG-AKGEVGPAGSPGSNGAPGQR 368
Query: 473 GPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDS 532
G + PQ ++ P G +GSP G GE+ P G G P
Sbjct: 369 G-EPGPQGHAGAQGPPGPPGINGSPG--------GKGEMGPAGIPG----------APGL 409
Query: 533 TQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRG-PSPEPPPSPLQVPTYPQLTLEV 591
R P +PG + ++ +G P P +P P E
Sbjct: 410 MGARGPPGPAGANGAPG-----LRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGED 464
Query: 592 PQAPEVLRSPGVPPSPCLPESY-------------PYGSPQEKS-LDKAGSESP------ 631
+ SPG P + LP + P G P EK + G+ P
Sbjct: 465 GKDG----SPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520
Query: 632 --HPGRR-------------TPGN--SSKKP----SQGSGRRPGDPGSTPLRDRLAALGK 670
PGR +PG S KP SQG RPG PG + R + +G
Sbjct: 521 AGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMG- 579
Query: 671 LKTGPEGALGSE-KNGVPARPGTEKTRG-PGKSGESA--------------GDMVPSIHR 714
GP+G G+ KNG PG +G PGK+GE+ GD P +
Sbjct: 580 -FPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQ 638
Query: 715 PLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTK 774
L+ L GG G + K EPG GD GA + G + D
Sbjct: 639 GLQGLPGTGGPPG------ENGKPGEPGPKGDAGA----PGAPGGKGD------------ 676
Query: 775 VELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPL 834
AGA + P A P G P P P PG
Sbjct: 677 --------AGAPGERGPPGLAGAPGLRGGAGPP--GPEGGKGAAGPPGPPGAAGTPGLQG 726
Query: 835 VTKE-----SPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEG 876
+ E SP P KG P G A P GP P+ GP G
Sbjct: 727 MPGERGGLGSPGPKGDKGEP----GGPGADGVPGKDGPRGPT-GPIG 768
Score = 55.8 bits (133), Expect = 3e-07
Identities = 107/420 (25%), Positives = 141/420 (33%), Gaps = 92/420 (21%)
Query: 126 PSEPPASPSLSSTEG-PAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDALSPFL 184
P+ PP + G P P G G R + PG PG P P + SP
Sbjct: 850 PAGPPGPQGVKGERGSPGGPGAAGF-PGARGL-------PGPPGSNGNPGPPGPSGSPG- 900
Query: 185 RKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPPQPEPSPWAPCL 244
++ P + P P GP GE G P + P AP
Sbjct: 901 -------------KDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEK-GSPGAQGPPGAP-- 944
Query: 245 LLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPS-----RGPPQAQGTSS-----GPNCAP 294
GP + G+ L G G G P GP G P A G S GP P
Sbjct: 945 --GPLGIAGITGARGLAGPPGMPGPRGSP-GPQGVKGESGKPGANGLSGERGPPGPQGLP 1001
Query: 295 GSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAG-PLNGD 353
G + + AG+P +P + L R + G + E+ G+ G P
Sbjct: 1002 GLAGT-----AGEPGRDGNPGS--DGLPGRDGSPGGKGDRGEN-------GSPGAPGAPG 1047
Query: 354 HPGP-------GQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFL 406
HPGP G+S ++ P P + G P+ R G T E +G
Sbjct: 1048 HPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGE-RGAAGI- 1105
Query: 407 SMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSE 466
G PG P S + IG P P +GP+ PS PP +
Sbjct: 1106 -----KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSG---------PPGKD 1151
Query: 467 KSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPC 526
+ GP + P PR +R GS+GSP G G G P +P PC
Sbjct: 1152 GTSGHPGP-IGPPGPRGNR---GERGSEGSP-----------GHPGQPGPPGPPGAPGPC 1196
Score = 32.7 bits (73), Expect = 2.4
Identities = 69/273 (25%), Positives = 81/273 (29%), Gaps = 42/273 (15%)
Query: 1060 PKSPWPACGP-RNGLVGPLQGCGKP-PGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGS 1117
P P A P GL GP G P P PS PG+ P P + A GS
Sbjct: 866 PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKD---------GPPGPAGNTGAPGS 916
Query: 1118 LTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLD-----------PPPGVPPARPPPL 1166
+ G P G G+P P P L PPG+P R P
Sbjct: 917 PGVSGPKGDAGQP----GEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPG 972
Query: 1167 TKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALLPAA--PGHRGHETCPDDPCEDPGP 1224
+ + E PG L P P L A PG G+ P D P
Sbjct: 973 PQGVKG----ESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSP 1028
Query: 1225 TPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGL-----PRTPMALPVDRKRSQEPSRP 1279
+N + A G P P G P P P SR
Sbjct: 1029 GGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAP-----GPAGSRG 1083
Query: 1280 SPTPQGPPFGGSRTPSTSDMAEEGRVASGGPPG 1312
+P PQGP T +G G PG
Sbjct: 1084 APGPQGPRGDKGETGERGAAGIKGHRGFPGNPG 1116
Score = 30.8 bits (68), Expect = 9.1
Identities = 43/179 (24%), Positives = 53/179 (29%), Gaps = 43/179 (24%)
Query: 1140 PSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFP 1199
P+ +P + + P P P RPP +G+ P P
Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPP------------------------NGQGPQGPKGD 110
Query: 1200 ALLPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGL 1259
P PG G P P P PP T P + S + + GL
Sbjct: 111 PGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVA-VGGL 169
Query: 1260 -----PRTPMALPVDRKRSQEPSRP-SPTPQGPPFGGSRTPSTSDMAEEGRVASGGPPG 1312
P P P S P P SP QGPP E G+ GPPG
Sbjct: 170 AGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPP------------GEPGQAGPSGPPG 216
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 86.3 bits (212), Expect = 2e-16
Identities = 191/769 (24%), Positives = 245/769 (31%), Gaps = 152/769 (19%)
Query: 162 LRPGGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGS 221
L P PG P PPP A L VL A L A
Sbjct: 25 LTPRPPGSPRPPPPVTPA----------ALRVLGAAGAVGRKPLAERA------------ 62
Query: 222 PEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRG-- 279
G + G PE +P A GP G RP RG
Sbjct: 63 -----GGIGGATIPESAPRA-----GPTR----------SAGTSSRNPASRPPASGRGER 102
Query: 280 PPQAQGTSSGPNCAPGSSSSS-------------SSDEA---GDPNEAPSPDTLLGALAR 323
P A+ TS GP +PG +S + S++E G EAP + L A AR
Sbjct: 103 APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK-RSALSAGAR 161
Query: 324 RQLNLGQLLEDTESYLQAFLAGAAGPLNG-DHPGPGQSSSPDQAPPQLSKSKGLPKSAWG 382
R + T S A + AAG G P P P P+ S S S
Sbjct: 162 R--DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219
Query: 383 GGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGS----------RPGHPHSSSQVKS 432
RP S G G S + + PL S P P SQ K
Sbjct: 220 PSPAARRRP-----SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274
Query: 433 K-------LQIGPP--SPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRN 483
K Q+ PP A GPL SP L P S S P L P P +
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSP------LATPSPSAALQSQAPPTL-PATPHS 327
Query: 484 SRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPD--STQLRPPQSA 541
S + C+ + +P PL SP L T PSP T P +T L P
Sbjct: 328 SSLTCQLA----TPLPL--------APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 375
Query: 542 LSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAP-----E 596
+ + P P +SP + P + PPSP P L PQAP
Sbjct: 376 ATHSFLPSPPLSP-LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434
Query: 597 VLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDP 656
+L++P PP P P P+ P + S S P + P + + P Q P P
Sbjct: 435 LLQAPFSPP-PSPPVQAPFSPPASPPV----SPSATPPSQAPPSLAAPPLQVPPSPPASP 489
Query: 657 GSTPLRDRLAALGKLKTGPEGALGSEKNGVP---ARPGTEKTRGPGKSGESAGDMVPSIH 713
+P P L P A P + P S PS
Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 549
Query: 714 RPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLT 773
P+ L Q P ++ P +V S + P P +
Sbjct: 550 LPMSPLATP--------------PPQAPPVLAAPLLQVPPSPPASPTLQ-APRRPPTPGP 594
Query: 774 KVELAKSRLAGALCPQVPRTPAKVPT---SAPSLGKPNKSPHSSPTKLPS-----KSPTK 825
++ RL AL P P P++ P+ S P L + S S+P +L +
Sbjct: 595 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 654
Query: 826 VVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGP 874
P P A L +G PP A G+ P P P P+ GP
Sbjct: 655 ASPPPDAELAACHPAAWSRGPAPPLAFRGA------PGAPLPWPPATGP 697
Score = 77.8 bits (190), Expect = 6e-14
Identities = 193/736 (26%), Positives = 242/736 (32%), Gaps = 164/736 (22%)
Query: 214 PPGQGPG--SPEPINGELCGPPQPEPSPWAPCLL--LGPGNLGGLLHWERLLGGLGG--- 266
P + PG +P P G P+P P P P L LG G GG+GG
Sbjct: 17 PAARAPGLLTPRPP-----GSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 267 -----------------EEDTGRPWGPSRGP--PQAQGTSSGPNCAPGSSSSS------- 300
RP RG P A+ TS GP +PG +S +
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 301 ------SSDEA---GDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLN 351
S++E G EAP L A ARR + T S A + AAG
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSAL-SAGARRDTS--GPTPGTPSPAMARRSRAAGTEV 187
Query: 352 G-DHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFM 410
G P P P P+ S S S RP S G G S +
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP-----SAGGGLQRPASRSL 242
Query: 411 GAGDAPLGS----------RPGHPHSSSQVKSK-------LQIGPP--SPGEAQGPLLPS 451
+ PL S P P SQ K K Q+ PP A GPL S
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
Query: 452 PARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGEL 511
P L P S S P L P P +S + C+ + +P PL
Sbjct: 303 P------LATPSPSAALQSQAPPTL-PATPHSSSLTCQLA----TPLPLAPP-------- 343
Query: 512 SPEGAQGLPTSPSPCYTTPD--STQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRG 569
SP L T PSP T P +T L P + + P P +SP
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP------------LAT 391
Query: 570 PSPEPPPS----PLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDK 625
P P+ PP+ PLQ P P P +P + SP PSP P + L
Sbjct: 392 PPPQAPPALALPPLQAPPSP------PASPPL--SPLATPSPQAPNALAV-----HLLQA 438
Query: 626 AGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNG 685
S P P + P + P P P +TP + +L +
Sbjct: 439 PFSPPPSPPVQAPFSPPASP-------PVSPSATP-----------PSQAPPSLAAPPLQ 480
Query: 686 VPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMG 745
VP P P S P + P QL AK + AL T L+
Sbjct: 481 VPPSPPASPPMSP--SATPPPQAPPPLAAPPLQL-AKPPPQAPPALATPPLQALPSPPAS 537
Query: 746 DPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLG 805
PG +S + P+SP + T A LA L P PA +P+L
Sbjct: 538 FPGQAPFSPSAS------LPMSPLA--TPPPQAPPVLAAPLLQVPPSPPA-----SPTLQ 584
Query: 806 KPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVP 865
P + P P S + PG P SP GP A S++A STP
Sbjct: 585 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL-SGPDLAG-HSSSATSTPEEL 642
Query: 866 GPTDPSQGPEGLAPHS 881
D GPEG A S
Sbjct: 643 RGYD--SGPEGGAAAS 656
Score = 64.3 bits (155), Expect = 7e-10
Identities = 108/387 (27%), Positives = 146/387 (37%), Gaps = 47/387 (12%)
Query: 116 PQIPLTPLQPPSEPPASPSLS--STEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPA-A 172
P + L PLQ P PPASP LS +T P AP L V Q P PP A
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALA-------VHLLQAPFSPPPSPPVQA 450
Query: 173 P--PPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEP-INGEL 229
P PPA +SP +Q L A P L P+ P PP +P P L
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAA-----PPLQVPPSPPASPPMSPSATPPPQAPPPL 505
Query: 230 CGPP--QPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGP-SRGPPQAQGT 286
PP +P P AP L P G P P + PPQA
Sbjct: 506 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 565
Query: 287 SSGPNC-APGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAG 345
+ P P S +S + +A P PDT +++ +L L ++ +
Sbjct: 566 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDT---SVSGPRLTLALAPGPPPPPSRSPSST 622
Query: 346 AAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGT----PEAHRPGFGATSEGQG 401
+GP G SSS P +L +G GG P+A + +G
Sbjct: 623 LSGP-----DLAGHSSSATSTPEEL---RGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674
Query: 402 PLPFLSMFMGAGDAPLGSRPG-HPHSSSQVKSKLQI-GPPSPGEAQGPLLPSPARGLKFL 459
P P L+ F GA APL P P S+ + + + GP S A G L P P+ G
Sbjct: 675 PAPPLA-FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG---- 729
Query: 460 KLPPTSEKSPSPGGPQLSPQLPRNSRI 486
+ K+ + G S + P+ +R+
Sbjct: 730 ---TSGGKAAAGAGAGASSRSPKQARL 753
Score = 63.5 bits (153), Expect = 1e-09
Identities = 148/619 (23%), Positives = 196/619 (31%), Gaps = 131/619 (21%)
Query: 116 PQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPP 175
P L PP+ P S S T A PLPL P P+APP
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLA------------------PPSPSAPPS 350
Query: 176 ALDALSPFLRKKAQILEVLRA--LEETDPLLLCSPATPWR-PPGQGPGSPEPINGELCGP 232
SP +Q L + L+ T L P +P PP Q P P L P
Sbjct: 351 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP--PALALPPLQAP 408
Query: 233 PQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNC 292
P P SP L L L P+ P PP Q S P
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQA----------PFSPPPSPP-VQAPFSPPAS 457
Query: 293 APGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNG 352
P S S++ +A AP LQ + A P
Sbjct: 458 PPVSPSATPPSQAPPSLAAPP-------------------------LQVPPSPPASPPMS 492
Query: 353 DHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHR-PGFGATSEGQGPL-PFLSMFM 410
P + P A P L +K P++ TP P A+ GQ P P S+ M
Sbjct: 493 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 552
Query: 411 GAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPS 470
+PL + P P + + + L PPSP + P L +P R PPT S
Sbjct: 553 ----SPLATPP--PQAPPVLAAPLLQVPPSPPAS--PTLQAPRR-------PPTPGPDTS 597
Query: 471 PGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTP 530
GP+L+ L +P P P P +P
Sbjct: 598 VSGPRLTLAL---------------APGP-----------------------PPPPSRSP 619
Query: 531 DSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLE 590
ST P + S++ + P E + G + PPP +P
Sbjct: 620 SSTLSGPDLAGHSSSATSTP------EELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 673
Query: 591 VPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSL-DKAGSES--PHPGR----RTPGNSSK 643
P P R P P P + P + ++ + G ES P PG +PG S
Sbjct: 674 GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG 733
Query: 644 KPSQGSGRRPGDPGSTPLRDRLA--ALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKS 701
K + G+G G +P + RL LG L+ L S + A G G G
Sbjct: 734 KAAAGAG--AGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG 791
Query: 702 GESAGDMVPSIHRPLEQLE 720
G G + L E
Sbjct: 792 GAEGGGVTGGARAALSDAE 810
Score = 58.9 bits (141), Expect = 3e-08
Identities = 115/448 (25%), Positives = 147/448 (32%), Gaps = 83/448 (18%)
Query: 114 SLPQIPLTPLQPPSEPPASPSLSSTEG--PAAPL-PLGHCAGQREVCWEQQLRPGGPGPP 170
+LP P TP + SP+L +T P+ PL PL Q P PP
Sbjct: 353 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412
Query: 171 AAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSP---EPING 227
A+PP LSP Q L LL + P PP Q P SP P++
Sbjct: 413 ASPP-----LSPLATPSPQAPNALAV-----HLLQAPFSPPPSPPVQAPFSPPASPPVSP 462
Query: 228 ELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTS 287
P Q PS AP L + P P PP + +
Sbjct: 463 SATPPSQAPPSLAAPPLQVPP--------------------------SPPASPPMSPSAT 496
Query: 288 SGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAA 347
P AP ++ A P +AP ALA L+ S +F A
Sbjct: 497 PPPQ-APPPLAAPPLQLAKPPPQAPP------ALATPP------LQALPSPPASFPGQAP 543
Query: 348 GPLNGDHPGPGQSSSPDQAPPQLSKS-KGLPKSAWGGGTPEAHR--PGFGATSEGQGPLP 404
+ P ++ P QAPP L+ +P S T +A R P G + GP
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603
Query: 405 FLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPL-LPSPARGLKFLKLPP 463
L++ PG P S+ S GP G + P RG
Sbjct: 604 TLAL-----------APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY------- 645
Query: 464 TSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSP 523
S GG SP P C + P+P LA RG G L A G ++
Sbjct: 646 ---DSGPEGGAAASPP-PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 701
Query: 524 SPC--YTTPDSTQLRPPQSALSTTLSPG 549
C Y T P AL SPG
Sbjct: 702 GLCTIYETEGPESATPAPGALDPGPSPG 729
Score = 54.3 bits (129), Expect = 8e-07
Identities = 63/231 (27%), Positives = 80/231 (34%), Gaps = 43/231 (18%)
Query: 1048 PEYGDFQPVSSDPKSPW---PACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSED--- 1101
P F P +S P SP P+ P + PLQ PP P P +
Sbjct: 447 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 506
Query: 1102 ----SLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPPPG 1157
LA+P P + + L S +FP + +PS +LP + P PPP
Sbjct: 507 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ---APFSPSASLPMS--PLATPPPQ 561
Query: 1158 VPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPAL-LPAAPGHRGHETCPD 1216
PP PL +VP PS PA P L P P G +T
Sbjct: 562 APPVLAAPLLQVP----------------------PSPPASPTLQAPRRPPTPGPDTSVS 599
Query: 1217 DP----CEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTP 1263
P PGP PP + + T AG SS P +L G P
Sbjct: 600 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS-ATSTPEELRGYDSGP 649
Score = 48.1 bits (113), Expect = 5e-05
Identities = 122/552 (22%), Positives = 179/552 (32%), Gaps = 95/552 (17%)
Query: 777 LAKSRLAGALCPQVPRTPA--KVPTSAPSLGK---------------PNKSPHSSPTKLP 819
L R G+ P P TPA +V +A ++G+ P +P + PT+
Sbjct: 24 LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA 83
Query: 820 SKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAP 879
S RP A + +P P K P S S PGP G +GL
Sbjct: 84 GTSSRNPASRPPASGRGERAP-PAKNTSP--GPVSSPGRASGTTRPGPL----GQKGL-- 134
Query: 880 HSAIEEKVMKGIEENVLRLQGQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATK 939
+ EE V +G + +R+ + R+TS + PA+ RR+ A
Sbjct: 135 RISAEETVARG-----KATEAPKRSALSAGARRDTSGPTPG-----TPSPAMARRSRAAG 184
Query: 940 NKEGAGGGSPLRREVKMEARKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGG 999
+ G +P R R E + +SS +
Sbjct: 185 TEVGLPRPAPSARP-------------------------RPPTEGPRKSVSSASEHSTTE 219
Query: 1000 PAPG----PNTGLGQVQGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQP 1055
P+P P+ G G + + A + + P +P+ Q
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279
Query: 1056 -----VSSDPKSPWPACGPRNG--LVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPVP 1108
V+ K PA GP + L P P + P LA P+P
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLP 339
Query: 1109 TSHFTACGSLT-RTLDSGIGTFPPPDHGSSGTPSKNLPKT--KPPRLDPPPGVPPARPPP 1165
+ + + +TL S T P S G+P+ + P L P PP PP
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 399
Query: 1166 LTKVPRRAHTLEREVPGIEELLV-SGRHPSMPAF-----PALLPAAPGHRGHETCPDDPC 1219
L P +A P + L S + P+ A P P +P + + P P
Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 459
Query: 1220 EDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRP 1279
P TPP Q + P PL PP P +P A P + + P
Sbjct: 460 VSPSATPPSQAPPSLAAP----------PLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509
Query: 1280 ----SPTPQGPP 1287
P PQ PP
Sbjct: 510 LQLAKPPPQAPP 521
Score = 45.8 bits (107), Expect = 3e-04
Identities = 109/434 (25%), Positives = 142/434 (32%), Gaps = 66/434 (15%)
Query: 926 SKLPALNR--RTEATKNKEGAGGGSPLRREVKMEARKLEAESLNISKLMAKAEDLRRALE 983
S+ PA R R KN SP R L + L IS A +A E
Sbjct: 92 SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG--KATE 149
Query: 984 EEK-AYLSSRARPRPGGPAPG-PNTGLGQ---VQGQLAGMYQGADTFMQQLLNRVDGKEL 1038
K + LS+ AR GP PG P+ + + G G+ + A + + K +
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 209
Query: 1039 PSKSWR---EPKPEY-------GDFQ------------PVSSDPKSPWPACGPRNGLVGP 1076
S S EP P G Q P+SS +S A G P
Sbjct: 210 SSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 269
Query: 1077 LQGCGKPPG-----KPSSEPGRREEMP-----SEDSLAEPVPTSHFTACGSLTRTLDSGI 1126
Q KP G P P R++ P S LA P P++ +
Sbjct: 270 SQP--KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS---------QAP 318
Query: 1127 GTFPPPDHGSSGTPSKNLP-KTKPPRLDPPPGV-----PPARPPPLTKVPRRAHTLEREV 1180
T P H SS T P PP PP + PPA PP + TL+
Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 378
Query: 1181 PGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTR 1240
+ +S P P L A P + + P P P TP Q PN
Sbjct: 379 SFLPSPPLSPLATPPPQAPPAL-ALPPLQAPPSPPASPPLSPLATPSPQA------PNAL 431
Query: 1241 AAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPSTS-DM 1299
A P PP P +P A P + PS+ P+ PP +P S M
Sbjct: 432 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491
Query: 1300 AEEGRVASGGPPGL 1313
+ PP L
Sbjct: 492 SPSATPPPQAPPPL 505
Score = 37.0 bits (84), Expect = 0.13
Identities = 73/307 (23%), Positives = 98/307 (31%), Gaps = 74/307 (24%)
Query: 1065 PACGPRNGLVGPLQGCGKPPGKPSSEP---GRREEMP-----SEDSLAEPVPTSHFTACG 1116
P PR GP + G P+S P GR E P S ++ P S T G
Sbjct: 71 PESAPR---AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 1117 SLTR---------TLDSGIGTFPPPDHGSS------------GTPSKNLPKTKPP---RL 1152
L + T+ G T P S GTPS + + +
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 1153 DPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHP--------------SMPAF 1198
P P ARP P T+ PR++ + E E + R P S A
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 1199 PALLPA--APGHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQ- 1255
P PA P RG P P + P + + P + PPR+
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQ----------------PKPKGLQALRPPQVTPPRKD 291
Query: 1256 ----LEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGPP 1311
L L +P+A P Q S+ PT P S T + + PP
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQ--SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP 349
Query: 1312 GLETSES 1318
L+T S
Sbjct: 350 SLQTLPS 356
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 85.1 bits (209), Expect = 4e-16
Identities = 202/780 (25%), Positives = 258/780 (33%), Gaps = 146/780 (18%)
Query: 207 SPATPWRPPGQGPGSPEPINGELCGP----------PQPEPSPWAPCLLLGPGNLGGLLH 256
S P P QG P+ I G+ P P+ EP P +GP G
Sbjct: 445 SAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRG 504
Query: 257 WERLLGGLGGEEDTGRPWGP-SRGPPQAQGTSSGPNCAPGS----SSSSSSDEAGDPNEA 311
G +G G P +RG P + G GP A G SS GDP
Sbjct: 505 PRGDPGTVGPPGPVGERGAPGNRGFPGSDGLP-GPKGAQGERGPVGSSGPKGSQGDPGRP 563
Query: 312 PSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLS 371
P G R L ++ E G GPL PG+ P PP
Sbjct: 564 GEP----GLPGARGLTGNPGVQGPE--------GKLGPLGA----PGEDGRP--GPPGSI 605
Query: 372 KSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVK 431
+G P S G P+ G E AG+A + + G P +V
Sbjct: 606 GIRGQPGSMGLPG-PKGSSGDPGKPGE-------------AGNAGVPGQRGAPGKDGEVG 651
Query: 432 SKLQIGPPS-PGEA--QGPLLPSPARGLKFLKLPPTSEKSPS----PGGP-QLSPQLPRN 483
+GPP GE QGP P+ +GL PP P PG P + P PR
Sbjct: 652 PSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRG 711
Query: 484 SRIPCRNSGSDGSP--SPLLARRGLGGGELSPEGAQGLP-TSPSPCYTTPDSTQLRPPQS 540
R N G G P + L +G+ GG P+G +G P S +P T P Q P +
Sbjct: 712 ER---GNPGERGEPGITGLPGEKGMAGGH-GPDGPKGSPGPSGTPGDTGPPGLQGMPGER 767
Query: 541 ALSTTLSP----GPVVSPCYENILDLSRSTFRG-PSPEPPPSPLQVPTYPQ--------- 586
++ T P G + E RG P P PP P PT +
Sbjct: 768 GIAGTPGPKGDRGGIGEKGAEGTA--GNDGARGLPGPLGPPGPAG-PTGEKGEPGPRGLV 824
Query: 587 --------------------LTLEVPQAPEVLRSPGVPPSPCLP-ESYPYGSPQEKSLDK 625
+ PQ P+ PGV P P + GSP + L
Sbjct: 825 GPPGSRGNPGSRGENGPTGAVGFAGPQGPD--GQPGVKGEPGEPGQKGDAGSPGPQGL-- 880
Query: 626 AGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKL-KTGPEGALGSE-K 683
AGS PH PG + +QG G PGS R+ G GP G LG K
Sbjct: 881 AGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSA---GRVGPPGPAGAPGPAGPLGEPGK 937
Query: 684 NGVPARPGTEKTR-------------GPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVA 730
G P G + GPG G+ D P P G RG V
Sbjct: 938 EGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQ-RGIVG 996
Query: 731 LGTNSLKQQEPGLMGDPG--ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCP 788
+ ++ PGL G G +V + + G + PV P V G P
Sbjct: 997 MPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPV--------GEPGP 1048
Query: 789 QVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRP-GAPLVTKESPKPDKGKG 847
+ P P ++G+ P LP P P GAP + D G
Sbjct: 1049 EGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAP--GDAGQRGDPGSR 1106
Query: 848 PPWADCGSTTAQSTPLVPGPTDPSQGPEG-LAPHSAIEEKVMKGIEENVLRLQGQERAPG 906
P G + +PGP QGP G H ++ KG LQG PG
Sbjct: 1107 GPIGPPGRAGKRG---LPGP----QGPRGDKGDHGDRGDRGQKG-HRGFTGLQGLPGPPG 1158
Score = 77.4 bits (189), Expect = 8e-14
Identities = 216/838 (25%), Positives = 273/838 (32%), Gaps = 166/838 (19%)
Query: 126 PSEPPASPSLSSTEGPAA-PLPLGHCAGQREVCWEQQLRPGGPGPPAAPP-PALDALS-P 182
P+ PP S GP P P G E Q PG PGPP P P D LS P
Sbjct: 133 PAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQ--PGAPGPPGHPSHPGPDGLSRP 190
Query: 183 FLRKKAQILE-------VLRALEETDPLLLCSP---------ATPWRPPGQGPGSPEPIN 226
F + A + E V P+ P A P PPG+ PG P P+
Sbjct: 191 FSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGE-PGDPGPMG 249
Query: 227 --------------------------GEL--CGPPQPEPSPWAPCLLLGPGNLG--GLLH 256
GE+ G P P AP L G+ G GL
Sbjct: 250 PIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEG 309
Query: 257 WERLLGGLGGEEDTGRPWGPS--------RGPPQAQGTSSGPNCAPGSSSSSSSDEAGDP 308
+ +G G + + G P GP RG P +G GP APG + G P
Sbjct: 310 PKGEVGAPGSKGEAG-PTGPMGAMGPLGPRGMPGERGRL-GPQGAPGQRGAH-----GMP 362
Query: 309 NEAPSPDTLLGALARRQL--NLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQA 366
+ P P LG N G + G AGP P Q +
Sbjct: 363 GK-PGPMGPLGIPGSSGFPGNPG-------------MKGEAGPTGARGPEGPQGQRGETG 408
Query: 367 PPQLSKSKGLPKSAWGGGTPEAH----RPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPG 422
PP S GLP + GTP A PG GP G + +PG
Sbjct: 409 PPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPG 468
Query: 423 HPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPR 482
P G P P QGP+ P G + + P + P P G + P
Sbjct: 469 DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGER---GAPG 525
Query: 483 NSRIPCRNSGSDGSPSPLLARRGLGG-GELSPEGAQGLPTSPSP-----CYTTPDSTQLR 536
N P GSDG P P A+ G G P+G+QG P P + ++
Sbjct: 526 NRGFP----GSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQ 581
Query: 537 PPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPE 596
P+ L +PG P + + RG P + +P P+ + P P
Sbjct: 582 GPEGKLGPLGAPGEDGRPGPPGSIGI-----RG-----QPGSMGLPG-PKGSSGDPGKPG 630
Query: 597 VLRSPGVPPSPCLP----ESYPYGSPQEKSLDKAGSESPHPGRR----------TPGNSS 642
+ GVP P E P G L E PG PG
Sbjct: 631 EAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGG 690
Query: 643 KKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSG 702
K QG PGDPG A+G L GP G G+ G PG T PG+ G
Sbjct: 691 KPGDQGV---PGDPG---------AVGPL--GPRGERGNP--GERGEPGI--TGLPGEKG 732
Query: 703 ESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVD 762
+ G H P G +G+ PGL G PG R + + G + D
Sbjct: 733 MAGG------HGP-------DGPKGSPGPSGTPGDTGPPGLQGMPGERGIAG-TPGPKGD 778
Query: 763 LEPVSPRSCLTKVELAKSR-LAGALCPQVPRTPA---KVPTSAPSLGKPNKSPHSSPTKL 818
+ + +R L G L P P P P +G P +P
Sbjct: 779 RGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGS--RGNPGSR 836
Query: 819 PSKSPTKVVPRPGAPLVTKESP--KPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGP 874
PT V G P P K + G+ D GS Q PGP P+ P
Sbjct: 837 GENGPTGAVGFAG-PQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP 893
Score = 75.5 bits (184), Expect = 3e-13
Identities = 178/676 (26%), Positives = 225/676 (33%), Gaps = 136/676 (20%)
Query: 126 PSEPPASPSLSSTEGPAAPL-PLGHCAGQREVCWEQQLRPGGPGPPA-----------AP 173
PS P P L+ G P P G Q PG PGPP
Sbjct: 652 PSGPVGPPGLAGERGEQGPPGPTGF-----------QGLPGPPGPPGEGGKPGDQGVPGD 700
Query: 174 PPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPP 233
P A+ L P + E +P + P G GP P+ G P
Sbjct: 701 PGAVGPLGPRGERG-------NPGERGEPGITGLPGEKGMAGGHGPDGPK-------GSP 746
Query: 234 QPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSS----- 288
P +P GP L G+ + G G + D G G A+GT+
Sbjct: 747 GPSGTPGDT----GPPGLQGMPGERGIAGTPGPKGDRG-----GIGEKGAEGTAGNDGAR 797
Query: 289 ---GPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAG 345
GP PG + + E G+P P L+G R N G E+ + F AG
Sbjct: 798 GLPGPLGPPGPAGPTG--EKGEPG----PRGLVGPPGSRG-NPGSRGENGPTGAVGF-AG 849
Query: 346 AAGP-----LNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRP-GFGATSEG 399
GP + G+ PGQ PQ GL G+P H P G G
Sbjct: 850 PQGPDGQPGVKGEPGEPGQKGDAGSPGPQ-----GL------AGSPGPHGPNGVPGLKGG 898
Query: 400 QGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLP--SPAR-GL 456
+G P G+ G P S+ +V GPP P A GP P P + G
Sbjct: 899 RGT-----------QGPPGAT-GFPGSAGRV------GPPGPAGAPGPAGPLGEPGKEGP 940
Query: 457 KFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNS--GSDGSPSP--LLARRGLGGGELS 512
L+ P S GP P P + P + G DG P P +RG+ G
Sbjct: 941 PGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMP-G 999
Query: 513 PEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSP 572
G +G+P P P TP P A PGPV P S P P
Sbjct: 1000 QRGERGMPGLPGPA-GTPGKV---GPTGATGDKGPPGPVGPPG-------SNGPVGEPGP 1048
Query: 573 EPPPSPLQVPTYPQLTLEVPQA--PEVLRSPGVPPSPCLPESYPYGSPQEK-SLDKAGSE 629
E P P E P PG +P P P G+P + GS
Sbjct: 1049 EGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPG--PVGAPGDAGQRGDPGSR 1106
Query: 630 SP--HPGRR----TPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEK 683
P PGR PG + +G GD G R G GP G G +
Sbjct: 1107 GPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQG--LPGPPGPNGEQ- 1163
Query: 684 NGVPARPGTEKTRG-PGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPG 742
G PG RG PG G S + P P+ G+RG+V EPG
Sbjct: 1164 -GSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPI----GPPGVRGSVGEAGPEGPPGEPG 1218
Query: 743 LMGDPGARVYSSHSMG 758
G PG + + ++G
Sbjct: 1219 PPGPPGPPGHLTAALG 1234
Score = 37.0 bits (84), Expect = 0.13
Identities = 63/266 (23%), Positives = 95/266 (35%), Gaps = 52/266 (19%)
Query: 636 RTPGNSSKKPSQGSGRRPGDPGSTP----LRDRLAALG-------------KLKTGPEGA 678
+TPG + +G + G+PG P +R R G K + GP G
Sbjct: 98 QTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGP 157
Query: 679 LGSE-KNGVPARPGTEKTRGPGKSGESAGDMVPSIHRP----LEQLEAKGGIRGAVALGT 733
G + + GVP +PG PG G + + RP + L+ K G+ V L
Sbjct: 158 QGIDGEPGVPGQPG-----APGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMP 212
Query: 734 NSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRT 793
S+ G +G G + GA P P G + P R
Sbjct: 213 GSV-----GPVGPRGPQGLQGQQGGAGPTGPPGEPGD------------PGPMGPIGSRG 255
Query: 794 PAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAP-LVTKESPKPDKGKGPPWAD 852
P P G+P + + +P ++ PGAP L + + KG P +
Sbjct: 256 PEGPPGKPGEDGEPGR--NGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGE 313
Query: 853 CGSTTAQSTPLVPGPTDP--SQGPEG 876
G+ ++ GPT P + GP G
Sbjct: 314 VGAPGSKGE---AGPTGPMGAMGPLG 336
Score = 37.0 bits (84), Expect = 0.13
Identities = 78/270 (28%), Positives = 96/270 (35%), Gaps = 57/270 (21%)
Query: 1072 GLVGPLQGCGKP--PGKPSSEPGRREEM--PSEDSLA-EPVPTSHFTACGSLTRTLDSGI 1126
G GP G+P G+P EPG++ + P LA P P G L G
Sbjct: 846 GFAGPQGPDGQPGVKGEPG-EPGQKGDAGSPGPQGLAGSPGPHGPNGVPG-----LKGGR 899
Query: 1127 GTFPPPDHGSSGTPSKNLPKTKPPRLDPP-PGVPPARPPPLTKVPRRAHTLEREVPGIEE 1185
GT PP G++G P R+ PP P P PL + + R PG
Sbjct: 900 GTQGPP--GATGFPGS------AGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHG 951
Query: 1186 LLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCED--PGPTPPVQLAKNWTFPNTRAAG 1243
V R P+ P P PG +G DP ED PGP P A T G
Sbjct: 952 R-VGDRGPAGP------PGGPGDKG------DPGEDGQPGPDGPPGPAGT-----TGQRG 993
Query: 1244 SSSDPLMCPPRQLEGLPR---TPMAL-PVDRKRSQEPSRP-----------SPTPQGPPF 1288
P R + GLP TP + P + P P P P+GP
Sbjct: 994 IVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPA- 1052
Query: 1289 GGSRTPSTSD-MAEEGRVASGGPPGLETSE 1317
G TP + E G GP GL S+
Sbjct: 1053 GNDGTPGRDGAVGERGDRGDPGPAGLPGSQ 1082
Score = 35.4 bits (80), Expect = 0.37
Identities = 71/308 (23%), Positives = 101/308 (32%), Gaps = 71/308 (23%)
Query: 627 GSESPHPGRRTPGNSSKKPSQGSGRRPGDPG-------------------STPLRDRLAA 667
GS+ P R G + QG PG PG S P ++A
Sbjct: 138 GSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAG 197
Query: 668 LGKLKTGPEGALGSEKNGVPARPGTEKTRGP-------GKSGESAGDMVPSIHRPLEQLE 720
L + + LGS+ +P G RGP G +G + P P+ +
Sbjct: 198 LDE-----KSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIG 252
Query: 721 AKG-----------------GIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDL 763
++G G G V + + PG G PG + + H
Sbjct: 253 SRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKG 312
Query: 764 EPVSPRSCLTKVELAKSRLAGALCPQVPR---------TPAKVPTSAPSLGKPNKSPHSS 814
E +P S K E + GA+ P PR P P + G P K
Sbjct: 313 EVGAPGS---KGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMG 369
Query: 815 PTKLPSKSPTKVVPRPGAPLVTKES-PKPDKGKGPPWADCGSTTAQ---STPLVPGP--T 868
P +P S PG P + E+ P +G P G T +P +PG T
Sbjct: 370 PLGIPGSSGF-----PGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGT 424
Query: 869 DPSQGPEG 876
D + G +G
Sbjct: 425 DGTPGAKG 432
Score = 33.1 bits (74), Expect = 1.8
Identities = 70/290 (24%), Positives = 90/290 (31%), Gaps = 60/290 (20%)
Query: 1060 PKSPWPACGPRN--------GLVGPLQGCGKP--PGKPSSE-PGRREEMPSEDSLAEPVP 1108
P P + GPR G GP G+P PG+P + P P D L+ P
Sbjct: 133 PAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFS 192
Query: 1109 TS-----HFTACGSLTRTLDSGIGTFPPPD----HGSSGTPSKNLPKTKPPRLDPP---- 1155
+ GS + +G P G G P +P P
Sbjct: 193 AQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIG 252
Query: 1156 ---PGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPAL--LPAAPGHRG 1210
P PP +P + R + E G P FP LP GHRG
Sbjct: 253 SRGPEGPPGKPGEDGEPGRNGNPGEVGFAG---------SPGARGFPGAPGLPGLKGHRG 303
Query: 1211 HETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPL-MCPPRQLEGLPRT-----PM 1264
H+ GP V P ++ + P+ P G+P P
Sbjct: 304 HKGL-------EGPKGEVGA------PGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQ 350
Query: 1265 ALPVDRKRSQEPSRPSPT-PQGPPFGGSRTPSTSDM-AEEGRVASGGPPG 1312
P R P +P P P G P G S P M E G + GP G
Sbjct: 351 GAPGQRGAHGMPGKPGPMGPLGIP-GSSGFPGNPGMKGEAGPTGARGPEG 399
Score = 31.2 bits (69), Expect = 7.0
Identities = 48/185 (25%), Positives = 62/185 (33%), Gaps = 20/185 (10%)
Query: 1135 GSSGTPSKNLPKTKPPRLDPPPGV-PPARPPPLTKV-PR--RAHTLEREVPGIEELLVSG 1190
G+ GTP P P PP PP P P P+ R + VPG +
Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482
Query: 1191 RHPSMPAF--PALLPAAPGHRGHETCPDDPCEDPGPT-PPVQLAKNWTFPNTRAAGSSSD 1247
P P P G RG P DPG PP + + N GS
Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRG-------PRGDPGTVGPPGPVGERGAPGNRGFPGSDGL 535
Query: 1248 PLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPSTSDMAEEGRVAS 1307
P P+ +G R P+ + +P RP G P T + EG++
Sbjct: 536 P---GPKGAQG-ERGPVGSSGPKGSQGDPGRPG--EPGLPGARGLTGNPGVQGPEGKLGP 589
Query: 1308 GGPPG 1312
G PG
Sbjct: 590 LGAPG 594
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 82.4 bits (202), Expect = 3e-15
Identities = 202/851 (23%), Positives = 277/851 (32%), Gaps = 186/851 (21%)
Query: 119 PLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALD 178
PL PPS P A+P + P+AP P Q P PP PP+L
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAP-PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384
Query: 179 ALSPFLRKKAQILEVLRA--------------------LEETDPLLLCSP-------ATP 211
+ P + L+A L+ T L SP +P
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP 444
Query: 212 WRPPGQGPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTG 271
RP P SP P+ L P P P + + P + +H + L L
Sbjct: 445 SRPASTPPDSP-PLQAPLSLPASP-PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQA 502
Query: 272 RPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQL 331
P + Q + + P+ +S ++ P+ AP P
Sbjct: 503 PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP----------------- 545
Query: 332 LEDTESYLQAFLAGAAGPLNGDH--PGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAH 389
L A+ PL H P + P QAPP + P++ TP
Sbjct: 546 -----------LQTASAPLTTPHLETPPCPAPCPLQAPPS-PLTTPPPETPSSIATPPPQ 593
Query: 390 RPGFGATSEGQG-PLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPL 448
P A+ QG P P LS PL + P P + + PPSP A PL
Sbjct: 594 APPALASPPLQGLPSPPLS--------PLATPP--PQAPPXLALPPLQAPPSP-PASPPL 642
Query: 449 ----LPSP----ARGLKFLKL---PPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSP 497
PSP A + L+ PP S +P P SP + ++ P + S +P
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
Query: 498 SPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYE 557
PL ++ P P SPS TP Q PP +A + P P SP
Sbjct: 703 -PL---------QVPPSPPASPPMSPS---ATP-PPQAPPPLAAPPLQVPPSPPASP--- 745
Query: 558 NILDLSRSTFRGPSPEPPP----SPLQVPTYPQLTLEV-------PQAPEVLRSPGVPPS 606
S P P PP PLQVP P +L + PQAP L +P +
Sbjct: 746 -----PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800
Query: 607 PCLPESYPYGSP--QEKSLDKAGSESPHPGR---------RTPGNSSKKPSQGSGRRPGD 655
P P S+P +P SL + +P P + P + P+ + RRP
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860
Query: 656 PGSTPLRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHRP 715
PG L GP P+R + GP +G S+ + P
Sbjct: 861 PGPDTSVSGPRLTLALAPGPPPP--------PSRSPSSTLSGPDLAGHSSS----ATSTP 908
Query: 716 LEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKV 775
E G G A P A + + H A P P +
Sbjct: 909 EELRGYDSGPEGGAAASP------------PPDAELAACHP--AAWSRGPAPPLA----- 949
Query: 776 ELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLV 835
GA +P PA P SA L T ++ P P PGA L
Sbjct: 950 ------FRGAPGAPLPWPPATGPGSADGL----------CTIYETEGPESATPAPGA-LD 992
Query: 836 TKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENV 895
SP GK A G+++ P Q G P A++ V++ +
Sbjct: 993 PGPSPGTSGGKAAAGAGAGASS----------RSPKQARLGELPLGALQASVVQHLLSRT 1042
Query: 896 LRLQGQERAPG 906
L L E A G
Sbjct: 1043 LLLAAAEGAAG 1053
Score = 76.3 bits (186), Expect = 2e-13
Identities = 191/744 (25%), Positives = 248/744 (33%), Gaps = 139/744 (18%)
Query: 214 PPGQGPG--SPEPINGELCGPPQPEPSPWAPCLL--LGPGNLGGLLHWERLLGGLGG--- 266
P + PG +P P G P+P P P P L LG G GG+GG
Sbjct: 17 PAARAPGLLTPRPP-----GSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 267 -----------------EEDTGRPWGPSRGP--PQAQGTSSGPNCAPGSSSSSSSDEAGD 307
RP RG P A+ TS GP +PG +S G
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS-------GT 123
Query: 308 PNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAP 367
P L A + G+ E + A AGA +G PG +P A
Sbjct: 124 TRPGPLGQKGLRISAEETVARGKATEAPKR--SALSAGARRDTSGPTPG-----TPSPAM 176
Query: 368 PQLSKSK----GLPK---SAWGGGTPEAHRPGFGATSEGQ--GPLPFLSMFMGAGDAPLG 418
+ S++ GLP+ SA E R + SE P P AG
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL-- 234
Query: 419 SRPGH---PHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQ 475
RP S++ + S + GP + G + P PS + L P PQ
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP----------PQ 284
Query: 476 LSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQL 535
++P PR P S SPL SP G + P P TP L
Sbjct: 285 VTP--PRKDAAPALGPLSS---SPLATP--------SPSGTKARPVPPPDNAATPLPATL 331
Query: 536 RPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPS----PLQVPTYPQLTLEV 591
PP L+T L P SP L S P + PPS P+Q P Q T+
Sbjct: 332 -PPSPPLATPLPLAP-PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ-TIPP 388
Query: 592 PQAPEVLRSPGV--PPSP----CLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKP 645
Q P L SP + PPSP L + GSP ++ + SP + + + S+
Sbjct: 389 IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA 448
Query: 646 SQGSGRRP-----GDPGSTPLRDRLAAL-----GKLKTGPEGALGSEKNGVPARPGTEKT 695
S P P S PL+ L+ L P AL S + P P +
Sbjct: 449 STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508
Query: 696 RGPGKSGESAGDMVPSIHR--------PLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDP 747
P ++ S PS+ PLE L + L T S P L P
Sbjct: 509 MPPLETQSSLAP--PSLQTPPASLTTPPLENLPS----LAPPPLQTASAPLTTPHLETPP 562
Query: 748 GARVYSSHSMGARVDL-EPVSPRSCLTKVELAKSRLAGALCPQVPRTP-----AKVPTSA 801
+ + + P +P S T A LA +P P P +
Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP 622
Query: 802 PSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAP-------LVTKESPKPDKGKGPPWADCG 854
P L P SP P SP P P AP L SP P P+
Sbjct: 623 PXLALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF---- 677
Query: 855 STTAQSTPLVPGPTDPSQGPEGLA 878
+ S P+ P T PSQ P LA
Sbjct: 678 -SPPASPPVSPSATPPSQAPPSLA 700
Score = 66.6 bits (161), Expect = 1e-10
Identities = 204/791 (25%), Positives = 264/791 (33%), Gaps = 141/791 (17%)
Query: 130 PASPSLSSTEGP-AAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPP-ALDALSP--FLR 185
PAS SLSS+ P ++P G A + P P P+ P P L AL P
Sbjct: 237 PASRSLSSSATPLSSPARSGPSA---------RGTPRAPAHPSQPKPKGLQALRPPQVTP 287
Query: 186 KKAQILEVLRALEETDPLLLCSPA-TPWRPPGQGPGSPEPINGELC-GPPQPEPSPWAPC 243
+ L L + PL SP+ T RP + P+ L PP P P AP
Sbjct: 288 PRKDAAPALGPLSSS-PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
Query: 244 LLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNC-APGSSSSSSS 302
P +L L P P+ P QA + + P AP S +
Sbjct: 347 SPSAPPSLQTL------------------PSPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388
Query: 303 DEAGDPNEAPS----PDTLLGALARRQLNLGQ-LLEDTESYLQAFLAGAAGPLNGDHPGP 357
+ +PS P L + + +LG L+ T S+L L P
Sbjct: 389 IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTS--PSR 446
Query: 358 GQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPF------LSMFMG 411
S+ PD P Q S LP S P A S PL S+
Sbjct: 447 PASTPPDSPPLQAPLS--LPAS------PPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498
Query: 412 AGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSP 471
+ APL S P ++++ + PPS L P L L PP S
Sbjct: 499 SPQAPLSSLIMPP-----LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553
Query: 472 GGPQL-SPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTP 530
P L +P P PC PSPL T+P P TP
Sbjct: 554 TTPHLETPPCPA----PCP---LQAPPSPL--------------------TTPPP--ETP 584
Query: 531 DSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPS----PLQVPTYPQ 586
S PPQ+ P + SP + + S P P+ PP PLQ P P
Sbjct: 585 SSIATPPPQA-------PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP 637
Query: 587 -------LTLEVPQAPE-----VLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPG 634
L PQAP +L++P PP P P P+ P + S S P
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPP-PSPPVQAPFSPPASPPV----SPSATPP 692
Query: 635 RRTPGNSSKKPSQGSGRRPGDPGSTP-LRDRLAALGKLKTGPEGALGSEKNGVPARPG-T 692
+ P + + P Q P P +P A L P S P P T
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT 752
Query: 693 EKTRGPGKSGESAGDMVPS--IHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGAR 750
R P + PS P+ L AK + AL T L+ PG
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPASLPMSPL-AKPPPQAPPALATPPLQALPSPPASFPGQA 811
Query: 751 VYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKS 810
+S + P+SP + T A LA L P PA +P+L P +
Sbjct: 812 PFSPSAS------LPMSPLA--TPPPQAPPVLAAPLLQVPPSPPA-----SPTLQAPRRP 858
Query: 811 PHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDP 870
P P S + PG P SP GP A S++A STP D
Sbjct: 859 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL-SGPDLAG-HSSSATSTPEELRGYD- 915
Query: 871 SQGPEGLAPHS 881
GPEG A S
Sbjct: 916 -SGPEGGAAAS 925
Score = 62.8 bits (151), Expect = 2e-09
Identities = 157/627 (25%), Positives = 208/627 (33%), Gaps = 104/627 (16%)
Query: 114 SLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGG-PGPPAA 172
+LP + PLQ S P +P L E P P P A + P PP
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHL---ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 173 PPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGP 232
PPAL A P + L L P L P P + P P SP P++
Sbjct: 594 APPAL-ASPPLQGLPSPPLSPLATPPPQAPPXLALP--PLQAPPSPPASP-PLS------ 643
Query: 233 PQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNC 292
P PSP AP L +H + P+ P PP Q S P
Sbjct: 644 PLATPSPQAPNAL--------AVHLLQ------------APFSPPPSPP-VQAPFSPPAS 682
Query: 293 APGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNG 352
P S S A P++AP +LA L + A+ P++
Sbjct: 683 PPVSPS------ATPPSQAPP------SLAAPPLQVPP------------SPPASPPMSP 718
Query: 353 DHPGPGQSSSPDQAPP-QLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQ-GPLPFLSMFM 410
P Q+ P APP Q+ S TP P A Q P P S+ M
Sbjct: 719 SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM 778
Query: 411 GAGDAPLGSRPGH-PHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPP------ 463
+PL P P + + + PP+ Q P PS + + L PP
Sbjct: 779 ----SPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 834
Query: 464 -TSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTS 522
+ P P SP L R P G D S S G L+ A G P
Sbjct: 835 LAAPLLQVPPSPPASPTLQAPRRPP--TPGPDTSVS---------GPRLTLALAPGPPPP 883
Query: 523 PSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVP 582
PS +P ST P + S++ + P E + G + PPP
Sbjct: 884 PS---RSPSSTLSGPDLAGHSSSATSTP------EELRGYDSGPEGGAAASPPPDAELAA 934
Query: 583 TYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSL-DKAGSES--PHPGR---- 635
+P P P R P P P + P + ++ + G ES P PG
Sbjct: 935 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 994
Query: 636 RTPGNSSKKPSQGSGRRPGDPGSTPLRDRLA--ALGKLKTGPEGALGSEKNGVPARPGTE 693
+PG S K + G+G G +P + RL LG L+ L S + A G
Sbjct: 995 PSPGTSGGKAAAGAG--AGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAA 1052
Query: 694 KTRGPGKSGESAGDMVPSIHRPLEQLE 720
G G G G + L E
Sbjct: 1053 GGSGGGPGGAEGGGVTGGARAALSDAE 1079
Score = 59.7 bits (143), Expect = 2e-08
Identities = 76/288 (26%), Positives = 97/288 (33%), Gaps = 49/288 (17%)
Query: 1048 PEYGDFQPVSSDPKSPW---PACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLA 1104
P F P +S P SP P+ P + PLQ PP P P + LA
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
Query: 1105 EP---VPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPA 1161
P VP S PP +P + T PPR+ P PP
Sbjct: 732 APPLQVPPS--------------------PP-----ASPPMSPSATPPPRVPPLLAAPPL 766
Query: 1162 RPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCED 1221
+ PP L + P L + ++P+ PA P + P P
Sbjct: 767 QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826
Query: 1222 PGP-TPPVQLAKNWTFPNTRAAGSS-----SDPLMCPPRQLEGLPRTPMALPVDRKRSQE 1275
P P PPV A P + A + P P + G PR +AL
Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG-PRLTLALAPG--PPPP 883
Query: 1276 PSR-PSPTPQGPPFGGSRTPSTS--------DMAEEGRVASGGPPGLE 1314
PSR PS T GP G + +TS D EG A+ PP E
Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 931
Score = 45.8 bits (107), Expect = 3e-04
Identities = 71/289 (24%), Positives = 99/289 (34%), Gaps = 33/289 (11%)
Query: 1054 QPVSSDPKSPWPACGPRNGLVGP-LQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHF 1112
+P S+ P SP P P + P LQ P P S P + + SLA P +
Sbjct: 446 RPASTPPDSP-PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL 504
Query: 1113 TACGSLTRTLDSGIGTFPP----PDHGSSGTPSKNLPKTKPP------------RLDPPP 1156
++ + L++ PP P + P +NLP PP L+ PP
Sbjct: 505 SSL--IMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPP 562
Query: 1157 GVPP----ARPPPLTKVPRRA-HTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGH 1211
P A P PLT P ++ P L S +P+ P A P +
Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP 622
Query: 1212 ETCPDDPCEDPGPTPPVQ------LAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMA 1265
P + P P+PP + PN A P PP P +P A
Sbjct: 623 PXLALPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681
Query: 1266 LPVDRKRSQEPSRPSPTPQGPPFGGSRTPSTS-DMAEEGRVASGGPPGL 1313
P + PS+ P+ PP +P S M+ PP L
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 730
Score = 42.7 bits (99), Expect = 0.002
Identities = 125/604 (20%), Positives = 199/604 (32%), Gaps = 138/604 (22%)
Query: 777 LAKSRLAGALCPQVPRTPA--KVPTSAPSLGK---------------PNKSPHSSPTKLP 819
L R G+ P P TPA +V +A ++G+ P +P + PT+
Sbjct: 24 LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA 83
Query: 820 SKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAP 879
S RP A + +P P K P S S PGP G +GL
Sbjct: 84 GTSSRNPASRPPASGRGERAP-PAKNTSP--GPVSSPGRASGTTRPGPL----GQKGL-- 134
Query: 880 HSAIEEKVMKGIEENVLRLQGQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATK 939
+ EE V +G + +R+ + R+TS + PA+ RR+ A
Sbjct: 135 RISAEETVARG-----KATEAPKRSALSAGARRDTSGPTPG-----TPSPAMARRSRAAG 184
Query: 940 NKEGAGGGSPLRREVKMEARKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGG 999
+ G +P R R E + +SS +
Sbjct: 185 TEVGLPRPAPSARP-------------------------RPPTEGPRKSVSSASEHSTTE 219
Query: 1000 PAPG----PNTGLGQVQGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQP 1055
P+P P+ G G + + A + + P +P+ Q
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279
Query: 1056 VSSDPKSPWPACGPRNGL---VGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHF 1112
+ +P PR +GPL P PS + +P D+ A P+P
Sbjct: 280 LRPPQVTP-----PRKDAAPALGPLSS--SPLATPSPSGTKARPVPPPDNAATPLPA--- 329
Query: 1113 TACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDP---PPGVPPARPPP-LTK 1168
T PP ++ P + PP L PP PP++ PP +T
Sbjct: 330 ---------------TLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT 374
Query: 1169 VPRRAHTLEREVPGIE----------------------ELLVSGRHPSMPAFPALLPAAP 1206
P +A + +P I+ + S P++ A + L +P
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434
Query: 1207 GH-RGHETCPDDPCEDPGPTPPVQLAKNWTFPN------TRAAGSSSDPLMCPPRQ-LEG 1258
+ T P P P +PP+Q + + A S PL P Q L
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494
Query: 1259 L----PRTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGPPGLE 1314
L P+ P++ + + S P+ Q PP + P + + S PP L+
Sbjct: 495 LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN-------LPSLAPPPLQ 547
Query: 1315 TSES 1318
T+ +
Sbjct: 548 TASA 551
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 81.6 bits (200), Expect = 4e-15
Identities = 253/1114 (22%), Positives = 363/1114 (32%), Gaps = 253/1114 (22%)
Query: 167 PGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGP-----GS 221
P PP PPP D P+ PW P P S
Sbjct: 446 PRPPPPPPPPRDGPFPW---------------------------PWPPAHSAPRPGTLSS 478
Query: 222 PEPINGELCGPPQPEPSPWAPCLLLGPG-NLGGLLHWERLLGGLGGEEDTGRP-WGPSRG 279
P P+ L G P +P G NL L WE+ G G G P W P+
Sbjct: 479 PFPL---LDGFPGADPDDVLTVTESSRGLNLECL--WEKARRGAG--RGGGAPAWQPASA 531
Query: 280 PPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQ----LLEDT 335
PP S P EA S ++L ++ R ++ LE+
Sbjct: 532 PPAPHANPSNPFY-----------------EALSTPSVLPVISARSPSVSSEYYIRLEEH 574
Query: 336 ESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGA 395
S + PL+ P P +P + P +S++ W A RP F A
Sbjct: 575 GSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSET-------WASPLFPAPRP-FPA 626
Query: 396 TSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARG 455
S G F+ +G P G G + P E G +P
Sbjct: 627 QSSASGS------FLLSGWDPEGRGAGETLAGD------------PAEVLGERGTAP--- 665
Query: 456 LKFLKLPPTSEKSPSPG--GPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSP 513
+++ E+ SPG L R +PC +G+ S L RG
Sbjct: 666 --WVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGG 723
Query: 514 EGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSP--CYENILDLSRSTFRG-- 569
A G P P D + LR + +L+ P +P + ++ + + G
Sbjct: 724 HPALGCPHPPE------DDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRG 777
Query: 570 --PSPEPPPSPLQVPTYPQLTLEVPQA----PEVLRSPGVPPSPCLPESYPYGSPQEKSL 623
P+P PPP P + P P + + P A L SPG P E+ SP+
Sbjct: 778 PPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPE--GA 835
Query: 624 DKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPL---RDRLAALGKLKTGPEGALG 680
G + G P + P G+ R P DPG PL R++ + ++ T E L
Sbjct: 836 FPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVST--EQLLM 893
Query: 681 S-----EKNGVPARPGTEKTRGPGKSGESAG--DMVPSIHRPLEQLEAKGGIRGAVALGT 733
S +N + + T + GP K+G G + VP ++R L G +++L
Sbjct: 894 SLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVL-GNGKQAPSLSLPV 952
Query: 734 NSLKQQEPGLMGDPG--ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLA-------- 783
N + E G PG + + ++G+ E V LT + L
Sbjct: 953 NGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPE 1012
Query: 784 --------GALCPQVPRTPAKVPTSAPSLGKPN--KSPHSSPTKLPSKSPTKVVPRPGAP 833
G L P P++ KV + N + P + P + P P + P P
Sbjct: 1013 AGEKVLVNGGLTP--PKSEDKVSENGGLRFPRNTERPPETGPWRAP--GPWEKTPESWGP 1068
Query: 834 LVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEE 893
T P P+ A ++++ G T P GP G AP + E G E
Sbjct: 1069 APTIGEPAPETSLERAPAPSAVVSSRN----GGETAP--GPLGPAPKNGTLE---PGTER 1119
Query: 894 NVLRLQGQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGAGGGSPLRRE 953
G RAPGA + L + R T G G GS + +
Sbjct: 1120 RAPETGGAPRAPGA----------------GRLDLGSGGRAPVGTGTAPGGGPGSGV--D 1161
Query: 954 VKMEARKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPR--PGGPAPGPNTGLGQV 1011
K L E R LE RARP P G P++ G
Sbjct: 1162 AKAGWVDNTRPQPPPPPLPPPPEAQPRRLEP----APPRARPEVAPEGEPGAPDSRAG-- 1215
Query: 1012 QGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSD-----------P 1060
G A G ++ G E+P + + + P G+ + + +
Sbjct: 1216 -GDTALSGDGDPPKPER-----KGPEMP-RLFLDLGPPQGNSEQIKARLSRLSLALPPLT 1268
Query: 1061 KSPWPACGPRN--------GLVGPLQGCGKPPGKPSSEPGRREEMPSED----------- 1101
+P+P GPR G G G PG P+ E G E+ E+
Sbjct: 1269 LTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPG-PAEEDGEDEDEDEEEDEEAAAPGAAA 1327
Query: 1102 -------SLAEPVP----TSHFTACGSLTRTLDSGIGTFPPPD------------HG--- 1135
+ A PVP ++ A L L S G P D HG
Sbjct: 1328 GPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVT 1387
Query: 1136 ----SSGTPSKNLPKTKPPRLDPPPGVPPARPPP 1165
TP+ L PP D P PPA P P
Sbjct: 1388 VYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTP 1421
Score = 78.2 bits (191), Expect = 5e-14
Identities = 215/835 (25%), Positives = 278/835 (33%), Gaps = 150/835 (17%)
Query: 416 PLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQ 475
P RP Q+ L PP P P P P R F P + +P PG
Sbjct: 423 PPAQRPSASDLQLQLTYLLSERPPRP-----PPPPPPPRDGPFPWPWPPAHSAPRPG--T 475
Query: 476 LSPQLPRNSRIPCRN--------SGSDGSPSPLL---ARRGLGGGELSPEGAQGLPTSPS 524
LS P P + S G L ARRG G G +P P S
Sbjct: 476 LSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAPAWQ---PASAP 532
Query: 525 PCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTY 584
P P + P ALST S PV+S ++ S R PP PL +
Sbjct: 533 PA---PHANPSNPFYEALSTP-SVLPVISARSPSVS--SEYYIRLEEHGSPPEPLFPNDW 586
Query: 585 PQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKK 644
L PGVP +P P++ P PQ S A P P R P SS
Sbjct: 587 DPL------------DPGVP-APQAPQA-PSEVPQLVSETWASPLFPAP-RPFPAQSSAS 631
Query: 645 PS---QGSGRRPGDPGSTPLRDRLAALGKLKTGP--EGALGSEKNGVPARPGTEKTRGPG 699
S G G T D LG+ T P E E+ P + GP
Sbjct: 632 GSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPS 691
Query: 700 KSGESAGDMVPSIHR-------PLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVY 752
+ G P R PLE+ +A G G ALG + + L +
Sbjct: 692 RRGPLP---CPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAE------ 742
Query: 753 SSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVP-RTPAKVPTSAPSLGKPNKSP 811
G+ DL P S + L GA PQ P R P P P + P
Sbjct: 743 ----RGSLADLPMAPPASAPPEF---LDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADP 795
Query: 812 HSSPTKLPSKSPTKVVPRPGAPLVTKESPKP-DKGK------GPPWADCGSTTAQSTPLV 864
+SP P V PG+ L + PKP D G P A G A+ V
Sbjct: 796 AASP------DPPSAVASPGSGL-SSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEG-V 847
Query: 865 PGPTDPSQGPEGLAPHSAIE---------------------EKVMKGIEENVLR-LQGQE 902
P P P + P+ AP + E+++ + E+V R L G++
Sbjct: 848 PRPRAPPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEK 907
Query: 903 RAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKN-KEGAGGGSPL----------R 951
A E R + K+P LNR N K+ P+ +
Sbjct: 908 GATARETGPRKAGRGPG----NREKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQ 963
Query: 952 REVKMEARKLEAESLNISKLMAKA---EDLRRALEEEKAYLSSRARPRPGGPAPGPNTGL 1008
R +E + E +L + K +L EEKA + R G N GL
Sbjct: 964 RAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGL 1023
Query: 1009 GQVQGQLAGMYQGADTFMQQLLN-------RVDGK-ELPSKSWREPKPEYGDFQPVSSDP 1060
+ + G F + R G E +SW P P G+ P +S
Sbjct: 1024 TPPKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWG-PAPTIGEPAPETSLE 1082
Query: 1061 KSPWPAC--GPRNG---LVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTAC 1115
++P P+ RNG GPL G P + EPG P E A P +
Sbjct: 1083 RAPAPSAVVSSRNGGETAPGPL---GPAPKNGTLEPGTERRAP-ETGGAPRAPGAGRLDL 1138
Query: 1116 GSLTRTLDSGIGTFPPPDHGS-----SGTPSKNLPKTKPPRLDPPPGVPPARPPP 1165
GS R G GT P GS +G P+ PP L PPP P R P
Sbjct: 1139 GSGGRA-PVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEP 1192
Score = 51.2 bits (121), Expect = 6e-06
Identities = 161/655 (24%), Positives = 221/655 (33%), Gaps = 147/655 (22%)
Query: 108 LQLTTGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGP 167
L+ GSL +P+ P P S PP L G AAP + G
Sbjct: 739 LRAERGSLADLPMAP--PASAPPEF--LDPLMGAAAP------------------QYPGR 776
Query: 168 GPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPA------------------ 209
GPP APPP P R A A P + SP
Sbjct: 777 GPPPAPPPP----PPPPRAPAD-----PAASPDPPSAVASPGSGLSSPGPKPGDSGYETE 827
Query: 210 TPWRPPGQGPGS--------------PEPINGELCGPPQPEPSPWAPCLLLGPGNLGGL- 254
TP+ P G PG PEP + G P+P P P P L GP
Sbjct: 828 TPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDP---GAPRPPPDP-GPLPLPGPREKPTFV 883
Query: 255 --LHWERLLGG---------LGGEEDTGRPWGP---SRGP---PQAQGTSSGPNCAPGSS 297
+ E+LL LG + T R GP RGP + G + P
Sbjct: 884 VQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGK 943
Query: 298 SSSSSD---------EAGDP-----NEAPSPDTLLGALARRQ--LNLGQLLEDTESYLQA 341
+ S E GD E + + LG+ R + L G+L
Sbjct: 944 QAPSLSLPVNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKAL 1003
Query: 342 FLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEA---HRPG-FGATS 397
P G+ +P ++ ++S++ GL PE PG + T
Sbjct: 1004 ENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTP 1063
Query: 398 EGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGE-AQGPLLPSPARGL 456
E GP P + AP S P S+ V S+ + GE A GPL P+P G
Sbjct: 1064 ESWGPAPTI-----GEPAPETSLERAPAPSAVVSSR------NGGETAPGPLGPAPKNG- 1111
Query: 457 KFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGA 516
P T ++P GG +P+ P R+ G +P+ GGG S A
Sbjct: 1112 --TLEPGTERRAPETGG---APRAPGAGRLDL----GSGGRAPVGTGTAPGGGPGSGVDA 1162
Query: 517 Q-GLPTSPSPCYTTPDSTQLRPPQSALSTTLSPG-----PVVSPCYENILDLSRS---TF 567
+ G + P P L PP A L P P V+P E SR+ T
Sbjct: 1163 KAGWVDNTRP---QPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTA 1219
Query: 568 RGPSPEPPPSPLQVPTYPQLTLEV--PQA-PEVLRSPGVPPSPCLP--ESYPYGSPQEKS 622
+PP + P P+L L++ PQ E +++ S LP P+ P +
Sbjct: 1220 LSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRR 1279
Query: 623 LDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEG 677
G+++ G G + P++ G D D AA GP G
Sbjct: 1280 PPWEGADAGAAGGEAGGAGAPGPAEEDGE---DEDEDEEEDEEAAAPGAAAGPRG 1331
Score = 38.9 bits (89), Expect = 0.033
Identities = 91/373 (24%), Positives = 110/373 (29%), Gaps = 90/373 (24%)
Query: 130 PASPSLSSTEGPAAPLPLGHCAG-------QREVCWEQQLRPGGPGPPAAPPPALDALSP 182
P + L G AP+ G G + W RP P PP PPP
Sbjct: 1131 PGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQP--- 1187
Query: 183 FLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPING---ELCG---PPQPE 236
R LE P A P P PG+P+ G L G PP+PE
Sbjct: 1188 ------------RRLEPAPP-----RARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPE 1230
Query: 237 -PSPWAPCLLLGPGNLGG-----LLHWERLLGGLGGEEDTGRPWGPSRGPP------QAQ 284
P P L L G G RL L T P R PP A
Sbjct: 1231 RKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGAA 1290
Query: 285 GTSSGPNCAPGSSSSSSSDEAGD---PNEAPSPDTLLGALARRQLNLGQLLEDTESYLQA 341
G +G APG + DE D EA +P G + + + +
Sbjct: 1291 GGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPV----PVVVSS 1346
Query: 342 FLAGAAGPLNGDHPGPGQSSSPD---------------------------------QAPP 368
A AA PL G P + P+ QAPP
Sbjct: 1347 ADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPP 1406
Query: 369 QLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSS 428
+ P + P PG G S G F F A D PL PG P S
Sbjct: 1407 EGDTDPSTPPAP--PTPPHPATPGDGFPSNDSG---FGGSFEWAEDFPLLPPPGPPLCFS 1461
Query: 429 QVKSKLQIGPPSP 441
+ + P P
Sbjct: 1462 RFSVSPALETPGP 1474
Score = 37.0 bits (84), Expect = 0.13
Identities = 45/155 (29%), Positives = 56/155 (36%), Gaps = 26/155 (16%)
Query: 1055 PVSSDPKSPWPACGPRNGLVGP-LQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFT 1113
P++ +P P G P G G PP P P R D A P P S
Sbjct: 750 PMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPA---DPAASPDPPSAVA 806
Query: 1114 ACGS--------------LTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPPPGV- 1158
+ GS T T S G FP G + +P+ + P P PG
Sbjct: 807 SPGSGLSSPGPKPGDSGYETETPFSPEGAFP----GGGAAEEEGVPRPRAPPEPPDPGAP 862
Query: 1159 -PPARPPPL-TKVPRRAHTLEREVPGIEELLVSGR 1191
PP P PL PR T +V E+LL+S R
Sbjct: 863 RPPPDPGPLPLPGPREKPTFVVQV-STEQLLMSLR 896
>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
Length = 1604
Score = 81.3 bits (199), Expect = 6e-15
Identities = 165/621 (26%), Positives = 207/621 (33%), Gaps = 115/621 (18%)
Query: 199 ETDPLLLCSPATPWRP--PGQ-GPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLL 255
E DP + SP P P PGQ G P + G GPP P P P + PG G L
Sbjct: 1011 EGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSP-GPPGPIGPPGFPGAVGSPGLPG--L 1067
Query: 256 HWERLLGGLGGEEDTGRPWGPSR-GPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEA--- 311
ER L GL G D G P P + G P A G P + S+ E G+P
Sbjct: 1068 QGERGLTGLTG--DKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSE 1125
Query: 312 --PSPDTLLGALARR--QLNLGQLLEDTESYLQAFLAGAAGPLNGDHPG-PGQSSSPDQA 366
P P G R Q N G+ D Q G GP PG PG+ SP
Sbjct: 1126 GLPGPPGPAGPRGERGPQGNSGEK-GDQGFQGQPGFPGPPGP-----PGFPGKVGSPGPP 1179
Query: 367 PPQLSKSK-------GLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGS 419
PQ K GLP S G P P +G+ P L GD
Sbjct: 1180 GPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLR-----GDPGPAG 1234
Query: 420 RPGHPHSSSQVKSKLQIGPPS-PGEAQGPLLPSPARGLKFLKLP-----PTSEKSPSPGG 473
PG +GPP G+ P LP P P P +E P G
Sbjct: 1235 PPG------------LMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMG 1282
Query: 474 PQLSPQLPRNSRIPCRNSGSDGSPSPL-------------LARRGLGG--GELSPEGAQG 518
PQ P P + P G G P P RGL G G+ P G G
Sbjct: 1283 PQGRPGPPGHVGPP----GPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPG 1338
Query: 519 LPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSP 578
P P T + P PGP P + R P P
Sbjct: 1339 PPGEPG----TDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKS 1394
Query: 579 LQV----PTYPQLTLEVPQAPEVLRSPGVPPSP-CLPESYPYGSPQE-------KSLDK- 625
+ P P P AP SPG+P P + + Y + K D+
Sbjct: 1395 GSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDER 1454
Query: 626 -----AGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKL--------- 671
+ + P PG G+ RPG PGS L ++ G+
Sbjct: 1455 MAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLP 1514
Query: 672 -KTGPEGALG---SEKNGVPARPGTEKTRGPGKSGESAGDM-------VPSIHRPLEQLE 720
G +G +G + +NG+P PG + G GK G + G M +P P+ Q
Sbjct: 1515 GTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMG-ATGPMGQQGIPGIPGPPGPMGQPG 1573
Query: 721 AKGGIRGAVALGTNSLKQQEP 741
G + G ++QQ P
Sbjct: 1574 KAGHCNPSDCFGAMPMEQQYP 1594
Score = 72.0 bits (175), Expect = 4e-12
Identities = 203/796 (25%), Positives = 254/796 (31%), Gaps = 192/796 (24%)
Query: 124 QPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDALSPF 183
+P + PA P +G A C + + RPG PGP
Sbjct: 707 EPGVQGPAGPKGEKGDGCTA------CPSLQGTVTDMAGRPGQPGPKG------------ 748
Query: 184 LRKKAQILEVLRALEETDPLLLCSPATPWRP--PG-QGPGSPEPINGELCGPPQ-----P 235
E P + P P +P PG QGP + + GE GPP P
Sbjct: 749 ---------------EQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEP-GPPGRGVQGP 792
Query: 236 EPSPWAPCL-----LLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPS----RGPPQAQGT 286
+ P AP L L GP G + G G + TG P GP GPP G
Sbjct: 793 QGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATG-PVGPPGASVSGPPGRDGQ 851
Query: 287 SSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGA 346
E G+P E P G L+ + GA
Sbjct: 852 QGQTGLRGTPGEKGPRGEKGEPGECSCPSQ------------GDLIFSG-------MPGA 892
Query: 347 AGPLNGDHPGPGQSSSPD----QAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGP 402
G G PG P PP + +G+P + G P G T+E G
Sbjct: 893 PGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQP-------GLTAE-LGS 944
Query: 403 LPFLSMFMGA--GDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLK 460
LP + + GD G R HP + K G P P L + A+ L+
Sbjct: 945 LPIEQHLLKSICGDCVQGQR-AHPGYLVEKGEKGDQGIPGV-----PGLDNCAQCFLSLE 998
Query: 461 LPPTSEK--SPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGG--GELSPEGA 516
P E S G P GS G P P GL G GE P G
Sbjct: 999 RPRAEEARGDNSEGDPGCV--------------GSPGLPGP----PGLPGQRGEEGPPGM 1040
Query: 517 QGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENIL-DLSRSTFRGPSPEPP 575
+G P P P + PP PG V SP + + + G EP
Sbjct: 1041 RGSPGPPGP---------IGPPGF-------PGAVGSPGLPGLQGERGLTGLTGDKGEPG 1084
Query: 576 PSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLD-KAGSESPHPG 634
P P Q P YP T P P + G S E G P + L G P
Sbjct: 1085 P-PGQ-PGYPGAT-GPPGLPGIKGERGYTGSA--GEKGEPGPPGSEGLPGPPGPAGPRGE 1139
Query: 635 RRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKN----GVPARP 690
R GNS +K QG +PG PG GP G G + G A
Sbjct: 1140 RGPQGNSGEKGDQGFQGQPGFPG--------------PPGPPGFPGKVGSPGPPGPQAEK 1185
Query: 691 GTEKTRGP-GKSGESAGDMVPSIHRP--LEQLEAKGGIRGAVALGTNSLKQQEPGLMGDP 747
G+E RGP G G P I P L+ L+ K G G L + PGLMG P
Sbjct: 1186 GSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPG---LRGDPGPAGPPGLMGPP 1242
Query: 748 GARVYSSHS--MGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLG 805
G + + H G + D P + GA+ PQ G
Sbjct: 1243 GFKGKTGHPGLPGPKGDCGKPGPPGSTGRP--GAEGEPGAMGPQ---------------G 1285
Query: 806 KPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVP 865
+P H P P +PG ++ K D+G G P P
Sbjct: 1286 RPGPPGHVGPPGPPG--------QPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHP 1337
Query: 866 GP-----TDPSQGPEG 876
GP TD + G EG
Sbjct: 1338 GPPGEPGTDGAAGKEG 1353
Score = 65.5 bits (158), Expect = 3e-10
Identities = 252/1083 (23%), Positives = 340/1083 (31%), Gaps = 191/1083 (17%)
Query: 215 PGQGPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPW 274
P PG P P+ G + P PC L G + R++ G + G P
Sbjct: 609 PAGSPGPPGPVGP--AGIKGAKGEPCEPCPALSNLQDGDV----RVVALPGPSGEKGEPG 662
Query: 275 GPSRGPPQAQGTSS--------------GPNCAPGSSSSSS-SDEAGDPNEA-PSPDTLL 318
P G P QG + G PG++ S E G A P +
Sbjct: 663 PPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGD 722
Query: 319 GALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPG-PGQSSSPD-QAPPQLSKSKGL 376
G A L G + + Q G GP PG PGQ P Q PP L +G
Sbjct: 723 GCTACPSLQ-GTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGE 781
Query: 377 PKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKL-Q 435
P G PG LP + G P + S VK
Sbjct: 782 PGPPGRGVQGPQGEPGAPG-------LPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGP 834
Query: 436 IGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRN----S 491
+GPP GP +G L+ +P GP+ P P + S
Sbjct: 835 VGPPG-ASVSGPPGRDGQQGQTGLR------GTPGEKGPRGEKGEPGECSCPSQGDLIFS 887
Query: 492 GSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSP-----CYTTPDSTQLRPPQSALSTTL 546
G G+P + G P+G G+P P P P + L P Q L+ L
Sbjct: 888 GMPGAPGLWMGSSWQPG----PQGPPGIPGPPGPPGVPGLQGVPGNNGL-PGQPGLTAEL 942
Query: 547 SPGPVVSPCYENILD------------LSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQA 594
P+ ++I L +G P L L+LE P+A
Sbjct: 943 GSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRA 1002
Query: 595 PEVLRS-----PGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGS 649
E PG SP LP P G P ++ G E P R +PG G
Sbjct: 1003 EEARGDNSEGDPGCVGSPGLPG--PPGLPGQR-----GEEGPPGMRGSPGPPGPIGPPGF 1055
Query: 650 GRRPGDPGSTPLRDRLAALG----KLKTGPEGALGSE-KNGVPARPGTEKTRGPGKSGES 704
G PG L+ G K + GP G G G P PG + RG S
Sbjct: 1056 PGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGE 1115
Query: 705 AGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPG-----------ARVYS 753
G+ P L G RG NS ++ + G G PG +V S
Sbjct: 1116 KGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGS 1175
Query: 754 SHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVP---RTPAKVPTSAPSLGKPNKS 810
G + + R S L G+ P P + PA + GKP
Sbjct: 1176 PGPPGPQAEKGSEGIRG--------PSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLR 1227
Query: 811 PHSSPTKLPS-KSPTKVVPRPGAPLVTKESPKPDKGK-GPPWA--------DCGSTTAQS 860
P P P + G P + PK D GK GPP + + G+ Q
Sbjct: 1228 GDPGPAGPPGLMGPPGFKGKTGHPGLP--GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQG 1285
Query: 861 TPLVPGPTDPSQGPEGLAPHSAIEEKVMKGI-----EENVLRLQGQERAPGAEVKHRNTS 915
P PG P GP G + I +KG E + L GQ PG H
Sbjct: 1286 RPGPPGHVGP-PGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPG----HPGPP 1340
Query: 916 SIASWFGLKKSKLPALNRRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNISKLMAKA 975
G + P + +G G + + + + R S M
Sbjct: 1341 GEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPV 1400
Query: 976 EDLRRALEEEKAYLSSRARPRPGGPAPGPNTGLGQVQGQLAGM--YQGADTFMQQLLNRV 1033
A E R PG P P + GL V G + M Y F++Q + ++
Sbjct: 1401 GPPGPAGE----------RGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKM 1450
Query: 1034 DGKELPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKP--PGKPSSEP 1091
+ + + R P +++ P P P ++G G G P PG+ E
Sbjct: 1451 FDERMAYYTSRMQFP-----MEMAAAPGRPGPP--GKDGAPGRPGAPGSPGLPGQIGRE- 1502
Query: 1092 GRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPR 1151
R+ +P L G+ D GIG G +G P
Sbjct: 1503 -GRQGLPGVRGLP-----------GTKGEKGDIGIGI-----AGENGLPG---------- 1535
Query: 1152 LDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGH 1211
PPG P PP K+ ++ +PGI P P P P GH
Sbjct: 1536 ---PPG--PQGPPGYGKMGATGPMGQQGIPGI---------PGPPG-PMGQPGKAGHCNP 1580
Query: 1212 ETC 1214
C
Sbjct: 1581 SDC 1583
Score = 60.8 bits (146), Expect = 8e-09
Identities = 96/337 (28%), Positives = 123/337 (36%), Gaps = 51/337 (15%)
Query: 129 PPASPSLSSTEGPAAPL----PLGHCAGQREVCWEQQLRPGGPGPPAAP--PPALDALSP 182
PP S L GPA P P G+ + + ++ Q PG PGPP P P + + P
Sbjct: 1121 PPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQ--PGFPGPPGPPGFPGKVGSPGP 1178
Query: 183 FLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPP--QPEPSPW 240
+ + E +R L SP P P QGP + ++G+ G P + +P P
Sbjct: 1179 PGPQAEKGSEGIRGPSG----LPGSPGPPGPPGIQGPAGLDGLDGK-DGKPGLRGDPGPA 1233
Query: 241 APCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGP-SRGPPQAQGT--SSGPNCAPGSS 297
P L+GP G L G G D G+P P S G P A+G + GP PG
Sbjct: 1234 GPPGLMGPPGFKGKTGHPGLPGPKG---DCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPP 1290
Query: 298 SSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGP 357
G P P G + L T A L G GP HPGP
Sbjct: 1291 G-----HVGPPGPPGQP----GPAGISAVGLKGDRGATGERGLAGLPGQPGP--PGHPGP 1339
Query: 358 GQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPL 417
D A + +G P G P A +GQ AG+
Sbjct: 1340 PGEPGTDGA----AGKEGPPGKQGFYGPPGPKGDPGAAGQKGQ-----------AGEKGR 1384
Query: 418 GSRPGHPHSSSQVKSKLQIGPPSP-GEAQGPLLPSPA 453
PG P S S +GPP P GE P P P+
Sbjct: 1385 AGMPGGPGKSG---SMGPVGPPGPAGERGHPGAPGPS 1418
Score = 59.3 bits (142), Expect = 2e-08
Identities = 295/1248 (23%), Positives = 388/1248 (31%), Gaps = 242/1248 (19%)
Query: 164 PGGPGPPAAPP----------------PALDALSPFLR-KKAQILEVLRALEETDPLLLC 206
PG PG P PP P P ++ +K EV L E +
Sbjct: 463 PGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVG 522
Query: 207 SPATPWRPPGQGPGSPEPINGE--LCGPPQPEPSPWAPC--------LLLGPGNLGGL-- 254
P P P G+ PG P P G+ + G + P C L+ G G +
Sbjct: 523 LPGKPG-PKGE-PGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGS 580
Query: 255 -------LHWERLLGGLGGEEDTGRPWGP--SRGPPQAQGTSS-----GPNCAPGSSSSS 300
L + GL GE+ GP S GPP G + G C P + S+
Sbjct: 581 PGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSN 640
Query: 301 SSDEAGDPNEAPSPDTLLGALARRQLNL-GQLLEDTESYLQAFLAGAAGPLNGDHPG--- 356
D P P G L G+ + E L+ A P + PG
Sbjct: 641 LQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTG 700
Query: 357 -PGQSSSPD---QAPPQLSKSKGLPK--SAWGGGTPEAHRPGFGATSEGQGPLPFLSMFM 410
PG S P A P+ K G S G T A RPG QGP
Sbjct: 701 RPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGP-------E 753
Query: 411 GAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGE--AQGPLLPSPARGLKFLKLPPTSEKS 468
G G +PG P K G P P QGP A GL ++ P
Sbjct: 754 GVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGP 813
Query: 469 PSPGGPQLSPQLP--RNSRIPCRNSGSDGSPSP----LLARRGLGG--GELSPEGAQGLP 520
P P G + + P + + P G+ S P + GL G GE P G +G P
Sbjct: 814 PGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEP 873
Query: 521 TSPSPCYTTPD---STQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPS 577
S C + D S P + ++ PGP P P P PP
Sbjct: 874 GECS-CPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGI-------------PGPPGPPG 919
Query: 578 PLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGS-PQEKSLDKAGSESPHPGRR 636
VP V + G+P P L GS P E+ L K+ G+R
Sbjct: 920 -------------VPGLQGVPGNNGLPGQPGLTAEL--GSLPIEQHLLKSICGDCVQGQR 964
Query: 637 T-PGNSSKKPSQGSGRRPGDPGSTPLRDRLAAL---------GKLKTGPEGALGSEKNGV 686
PG +K +G PG PG +L G G G +GS G+
Sbjct: 965 AHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSP--GL 1022
Query: 687 PARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGD 746
P PG PG+ GE E G+RG+ PG +G
Sbjct: 1023 PGPPGL-----PGQRGE----------------EGPPGMRGSPGPPGPIGPPGFPGAVGS 1061
Query: 747 PGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSL-G 805
PG L + LT + K P P A P P + G
Sbjct: 1062 PG--------------LPGLQGERGLTGLTGDKGEPGPPGQPGYPG--ATGPPGLPGIKG 1105
Query: 806 KPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVP 865
+ + + P ++ +P P P P+ ++G + G Q P P
Sbjct: 1106 ERGYTGSAGEKGEPGPPGSEGLPGPPGPA----GPRGERGPQGNSGEKGDQGFQGQPGFP 1161
Query: 866 GPTDPSQGPEGLA---PHSAIEEKVMKGIEENVLRLQGQERAPGAEVKHRNTSSIASWFG 922
GP P P + P EK +GI L G PG A G
Sbjct: 1162 GPPGPPGFPGKVGSPGPPGPQAEKGSEGIR-GPSGLPGSPGPPGPP----GIQGPAGLDG 1216
Query: 923 LK-KSKLPALNRRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNISKLMAKAEDLRRA 981
L K P L R G G P + K L + K R
Sbjct: 1217 LDGKDGKPGL-RGDPGPAGPPGLMG--PPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPG 1273
Query: 982 LEEEKAYLSSRARPRPGGPA--PGPNTGLGQVQGQLAGMYQGADTFMQQLLNRVDGKELP 1039
E E + + RP P G PGP G G+ ++ L + G+ P
Sbjct: 1274 AEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGP 1333
Query: 1040 SKSWREPKPEYGDFQPVSSDPKSPWPACGPRN----GLVGP--LQGCGKPPGKPSSEPGR 1093
P P P P G GP QG PPG P +PG
Sbjct: 1334 --------------------PGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPG-PKGDPGA 1372
Query: 1094 REEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLD 1153
+ GS+ +G PP G G P P P
Sbjct: 1373 AGQKGQAGEKGRAGMPGGPGKSGSM-----GPVG--PPGPAGERGHPGAPGPSGSPGL-- 1423
Query: 1154 PPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHET 1213
PGVP + + + + + +E + + S FP + AAPG
Sbjct: 1424 --PGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAY--YTSRMQFPMEMAAAPGR----- 1474
Query: 1214 CPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKR- 1272
P P +D P P A GS P +GLP LP +
Sbjct: 1475 -PGPPGKDGAPGRP------------GAPGSPGLPGQIGREGRQGLPGV-RGLPGTKGEK 1520
Query: 1273 -------SQEPSRPSPT-PQGPPFGGSRTPSTSDMAEEGRVASGGPPG 1312
+ E P P PQGPP G + +T M ++G GPPG
Sbjct: 1521 GDIGIGIAGENGLPGPPGPQGPP-GYGKMGATGPMGQQGIPGIPGPPG 1567
Score = 55.1 bits (131), Expect = 4e-07
Identities = 137/532 (25%), Positives = 175/532 (32%), Gaps = 107/532 (20%)
Query: 271 GRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQ 330
G+ P P+ GP PG GDP P P G+
Sbjct: 432 GQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGS---------- 481
Query: 331 LLEDTESYLQAFLAGAAGPLNGDHPG----PGQSSSPDQAPPQLSK---------SKGLP 377
+ + G GP G PG G+ P + P L + K P
Sbjct: 482 ----------SGIPGKEGP--GGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGP 529
Query: 378 KSAWGGGTPEAHRPGF-GATSEGQGPLPFLSMFMGA----------GDA-----PLGSRP 421
K G P PG G E P S +GA GD L P
Sbjct: 530 KGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLP 589
Query: 422 GHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLP 481
G K G P + GP P G+K K P P P L
Sbjct: 590 GRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPC---EPCPALSNLQDGDV 646
Query: 482 RNSRIPCRNSGSDGSPSP----LLARRGLGG--GELSPEGAQGLPTSPSPCYTTPDSTQL 535
R +P SG G P P L ++G G G +G G P P TP +T
Sbjct: 647 RVVALP-GPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPG----TPGTTG- 700
Query: 536 RPPQSALSTTLSP---------GPVVSPCYE-NILDLS-RSTFRGPSPEPPPSPLQVPTY 584
RP S P G P + + D++ R GP E P + P
Sbjct: 701 RPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGK 760
Query: 585 P-QLTLEVPQAPEVLRS-PGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSS 642
P Q L Q P L+ G P P P G P L G + R PG +
Sbjct: 761 PGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGL--PGIQGLPGPRGPPGPTG 818
Query: 643 KKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSE-KNGVPARPGTEKTRG-PGK 700
+K +QGS PG G+T + G +GP G G + + G+ PG + RG G+
Sbjct: 819 EKGAQGS---PGVKGAT---GPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGE 872
Query: 701 SGE----SAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPG 748
GE S GD++ S G+ GA L S +PG G PG
Sbjct: 873 PGECSCPSQGDLIFS------------GMPGAPGLWMGS--SWQPGPQGPPG 910
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 80.1 bits (196), Expect = 1e-14
Identities = 200/820 (24%), Positives = 260/820 (31%), Gaps = 174/820 (21%)
Query: 162 LRPGGPGPPAAPPPALDALSPFLRKKAQILEVLRA----------LEETDPLLLCSPATP 211
L P PG P PPP A L + A + E+ P P
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR--AGPTRT 82
Query: 212 WRPPGQGPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLG--GL-LHWERLLG------ 262
RPP G G P P P SP PG LG GL + E +
Sbjct: 83 SRPPASGRGERAPPAKNTS--PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140
Query: 263 -------GLGGEEDTGRPWGPSRGPP--------QAQGTSSG------------PNCAPG 295
G DT GP+ G P +A GT G P P
Sbjct: 141 APKRSALSAGARRDTS---GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 197
Query: 296 SSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGD-H 354
S SS+S+ + PSP ARR+ + G L+ S L+ +A PL+
Sbjct: 198 KSVSSASEHS---TTEPSP------AARRRPSAGGGLQRPAS---RSLSSSATPLSSPAR 245
Query: 355 PGPGQSSSPDQ-APPQLSKSKGLPKSAWGGGTPEAH--RPGFGATSEGQGPLPFLSMFMG 411
GP +P A P K KGL TP P G S P S
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305
Query: 412 AGDAPLGSRPGHPHSSSQVKSKLQIGPPS--------PGEAQGPLLPSPARGLKFLKLPP 463
P P ++ ++ +G P+ P PL P + L LPP
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 464 TSEKSPSPGGPQLSP------QLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQ 517
P P LSP Q P + + PSP + SP +
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ------APFSPPASP 419
Query: 518 GLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPS 577
P SPS TP S Q P +A + P P SP S P P+ PP
Sbjct: 420 --PVSPS---ATPPS-QAPPSLAAPPLQVPPSPPASP--------PMSPSATPPPQAPP- 464
Query: 578 PLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSP--QEKSLDKAGSESPHPGR 635
PL P QL PQAP L +P + P P S+P +P SL + +P P
Sbjct: 465 PLAAPPL-QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 523
Query: 636 ---------RTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGV 686
+ P + P+ + RRP PG L GP
Sbjct: 524 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP-------- 575
Query: 687 PARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGD 746
P+R + GP +G S+ + P E G G A
Sbjct: 576 PSRSPSSTLSGPDLAGHSSS----ATSTPEELRGYDSGPEGGAAASP------------P 619
Query: 747 PGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGK 806
P A + + H A P P + GA +P PA P SA L
Sbjct: 620 PDAELAACHP--AAWSRGPAPPLA-----------FRGAPGAPLPWPPATGPGSADGL-- 664
Query: 807 PNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPG 866
T ++ P P PGA L SP GK A G+++
Sbjct: 665 --------CTIYETEGPESATPAPGA-LDPGPSPGTSGGKAAAGAGAGASS--------- 706
Query: 867 PTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPG 906
P Q G P A++ V++ + L L E A G
Sbjct: 707 -RSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAG 745
Score = 77.4 bits (189), Expect = 8e-14
Identities = 184/705 (26%), Positives = 238/705 (33%), Gaps = 141/705 (20%)
Query: 214 PPGQGPG--SPEPINGELCGPPQPEPSPWAPCLL--LGPGNLGGLLHWERLLGGLGGEE- 268
P + PG +P P G P+P P P P L LG G GG+GG
Sbjct: 17 PAARAPGLLTPRPP-----GSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 269 ----------DTGRPWGPSRGP--PQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDT 316
T RP RG P A+ TS GP +PG +S G P
Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRAS-------GTTRPGPLGQK 123
Query: 317 LLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKG- 375
L A + G+ E + A AGA +G PG +P A + S++ G
Sbjct: 124 GLRISAEETVARGKATEAPKR--SALSAGARRDTSGPTPG-----TPSPAMARRSRAAGT 176
Query: 376 ---LPK---SAWGGGTPEAHRPGFGATSEGQG--PLPFLSMFMGAGDAPLGSRPGHPHSS 427
LP+ SA E R + SE P P AG RP S
Sbjct: 177 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL--QRPASRSLS 234
Query: 428 SQ---VKSKLQIGPPSPGEAQGPLLPSPAR--GLKFLKLPPTSEKSPSPGGPQLSPQLPR 482
S + S + GP + G + P PS + GL+ L+ PP P L P
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR-PPQVTPPRKDAAPALGPL--- 290
Query: 483 NSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPD--STQLRPPQS 540
+S +PSP SP L T PSP T P +T L P
Sbjct: 291 -------SSSPLATPSP--------SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335
Query: 541 ALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPS----PLQVPTYPQLTLEVPQAPE 596
+ + P P +SP P P+ PP+ PLQ P P P +P
Sbjct: 336 QATHSFLPSPPLSP------------LATPPPQAPPALALPPLQAPPSP------PASPP 377
Query: 597 VLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDP 656
+ SP PSP P + L S P P + P + P P P
Sbjct: 378 L--SPLATPSPQAPNALAV-----HLLQAPFSPPPSPPVQAPFSPPASP-------PVSP 423
Query: 657 GSTPLRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHRPL 716
+TP + +L + VP P P S P + P
Sbjct: 424 SATP-----------PSQAPPSLAAPPLQVPPSPPASPPMSP--SATPPPQAPPPLAAPP 470
Query: 717 EQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVE 776
QL AK + AL T L+ PG +S + P+SP + T
Sbjct: 471 LQL-AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS------LPMSPLA--TPPP 521
Query: 777 LAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVT 836
A LA L P PA +P+L P + P P S + PG P
Sbjct: 522 QAPPVLAAPLLQVPPSPPA-----SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576
Query: 837 KESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHS 881
SP GP A S++A STP D GPEG A S
Sbjct: 577 SRSPSSTL-SGPDLAG-HSSSATSTPEELRGYD--SGPEGGAAAS 617
Score = 64.7 bits (156), Expect = 6e-10
Identities = 145/615 (23%), Positives = 196/615 (31%), Gaps = 125/615 (20%)
Query: 120 LTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDA 179
L L+PP P + GP + PL + P P P+APP
Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPS------------PSAPPSPSAPPSLQTL 315
Query: 180 LSPFLRKKAQILEVLRA--LEETDPLLLCSPATPWR-PPGQGPGSPEPINGELCGPPQPE 236
SP +Q L + L+ T L P +P PP Q P P L PP P
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP--PALALPPLQAPPSPP 373
Query: 237 PSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGS 296
SP L L L P+ P PP Q S P P S
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQA----------PFSPPPSPP-VQAPFSPPASPPVS 422
Query: 297 SSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPG 356
S++ +A AP LQ + A P
Sbjct: 423 PSATPPSQAPPSLAAPP-------------------------LQVPPSPPASPPMSPSAT 457
Query: 357 PGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHR-PGFGATSEGQGPL-PFLSMFMGAGD 414
P + P A P L +K P++ TP P A+ GQ P P S+ M
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM---- 513
Query: 415 APLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGP 474
+PL + P P + + + L PPSP + P L +P R PPT S GP
Sbjct: 514 SPLATPP--PQAPPVLAAPLLQVPPSPPAS--PTLQAPRR-------PPTPGPDTSVSGP 562
Query: 475 QLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQ 534
+L+ L +P P P P +P ST
Sbjct: 563 RLTLAL---------------APGP-----------------------PPPPSRSPSSTL 584
Query: 535 LRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQA 594
P + S++ + P E + G + PPP +P P
Sbjct: 585 SGPDLAGHSSSATSTP------EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 638
Query: 595 PEVLRSPGVPPSPCLPESYPYGSPQEKSL-DKAGSES--PHPGR----RTPGNSSKKPSQ 647
P R P P P + P + ++ + G ES P PG +PG S K +
Sbjct: 639 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 698
Query: 648 GSGRRPGDPGSTPLRDRLA--ALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESA 705
G+G G +P + RL LG L+ L S + A G G G G
Sbjct: 699 GAG--AGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEG 756
Query: 706 GDMVPSIHRPLEQLE 720
G + L E
Sbjct: 757 GGVTGGARAALSDAE 771
Score = 64.3 bits (155), Expect = 7e-10
Identities = 108/387 (27%), Positives = 146/387 (37%), Gaps = 47/387 (12%)
Query: 116 PQIPLTPLQPPSEPPASPSLS--STEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPA-A 172
P + L PLQ P PPASP LS +T P AP L V Q P PP A
Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALA-------VHLLQAPFSPPPSPPVQA 411
Query: 173 P--PPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEP-INGEL 229
P PPA +SP +Q L A P L P+ P PP +P P L
Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLAA-----PPLQVPPSPPASPPMSPSATPPPQAPPPL 466
Query: 230 CGPP--QPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGP-SRGPPQAQGT 286
PP +P P AP L P G P P + PPQA
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526
Query: 287 SSGPNC-APGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAG 345
+ P P S +S + +A P PDT +++ +L L ++ +
Sbjct: 527 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDT---SVSGPRLTLALAPGPPPPPSRSPSST 583
Query: 346 AAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGT----PEAHRPGFGATSEGQG 401
+GP G SSS P +L +G GG P+A + +G
Sbjct: 584 LSGP-----DLAGHSSSATSTPEEL---RGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635
Query: 402 PLPFLSMFMGAGDAPLGSRPG-HPHSSSQVKSKLQI-GPPSPGEAQGPLLPSPARGLKFL 459
P P L+ F GA APL P P S+ + + + GP S A G L P P+ G
Sbjct: 636 PAPPLA-FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG---- 690
Query: 460 KLPPTSEKSPSPGGPQLSPQLPRNSRI 486
+ K+ + G S + P+ +R+
Sbjct: 691 ---TSGGKAAAGAGAGASSRSPKQARL 714
Score = 58.9 bits (141), Expect = 3e-08
Identities = 115/448 (25%), Positives = 147/448 (32%), Gaps = 83/448 (18%)
Query: 114 SLPQIPLTPLQPPSEPPASPSLSSTEG--PAAPL-PLGHCAGQREVCWEQQLRPGGPGPP 170
+LP P TP + SP+L +T P+ PL PL Q P PP
Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 373
Query: 171 AAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSP---EPING 227
A+PP LSP Q L LL + P PP Q P SP P++
Sbjct: 374 ASPP-----LSPLATPSPQAPNALAV-----HLLQAPFSPPPSPPVQAPFSPPASPPVSP 423
Query: 228 ELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTS 287
P Q PS AP L + P P PP + +
Sbjct: 424 SATPPSQAPPSLAAPPLQVPP--------------------------SPPASPPMSPSAT 457
Query: 288 SGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAA 347
P AP ++ A P +AP ALA L+ S +F A
Sbjct: 458 PPPQ-APPPLAAPPLQLAKPPPQAPP------ALATPP------LQALPSPPASFPGQAP 504
Query: 348 GPLNGDHPGPGQSSSPDQAPPQLSKS-KGLPKSAWGGGTPEAHR--PGFGATSEGQGPLP 404
+ P ++ P QAPP L+ +P S T +A R P G + GP
Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 564
Query: 405 FLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPL-LPSPARGLKFLKLPP 463
L++ PG P S+ S GP G + P RG
Sbjct: 565 TLAL-----------APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY------- 606
Query: 464 TSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSP 523
S GG SP P C + P+P LA RG G L A G ++
Sbjct: 607 ---DSGPEGGAAASPP-PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 662
Query: 524 SPC--YTTPDSTQLRPPQSALSTTLSPG 549
C Y T P AL SPG
Sbjct: 663 GLCTIYETEGPESATPAPGALDPGPSPG 690
Score = 54.3 bits (129), Expect = 8e-07
Identities = 63/231 (27%), Positives = 80/231 (34%), Gaps = 43/231 (18%)
Query: 1048 PEYGDFQPVSSDPKSPW---PACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSED--- 1101
P F P +S P SP P+ P + PLQ PP P P +
Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 467
Query: 1102 ----SLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPPPG 1157
LA+P P + + L S +FP + +PS +LP + P PPP
Sbjct: 468 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ---APFSPSASLPMS--PLATPPPQ 522
Query: 1158 VPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPAL-LPAAPGHRGHETCPD 1216
PP PL +VP PS PA P L P P G +T
Sbjct: 523 APPVLAAPLLQVP----------------------PSPPASPTLQAPRRPPTPGPDTSVS 560
Query: 1217 DP----CEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTP 1263
P PGP PP + + T AG SS P +L G P
Sbjct: 561 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS-ATSTPEELRGYDSGP 610
Score = 52.8 bits (125), Expect = 2e-06
Identities = 84/370 (22%), Positives = 117/370 (31%), Gaps = 61/370 (16%)
Query: 999 GPAPGPNTGLGQVQGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSS 1058
GP P G + G +G ++ + R E P +S P
Sbjct: 103 GPVSSPGRASGTTRPGPLGQ-KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT-- 159
Query: 1059 DPKSPWPACGPRNGLVGPLQGCGKP-----PGKPSSEPGRREEMPSEDSLAEPVP----- 1108
P +P PA R+ G G +P P P+ P + SE S EP P
Sbjct: 160 -PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 218
Query: 1109 ---------------TSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLD 1153
+S T S R+ S GT P H S P K L +PP++
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP-KGLQALRPPQVT 277
Query: 1154 PP--------------------PGVPPA--RPPPLTKVPRRAHTLEREVP-GIEELLVSG 1190
PP P PP+ PP L +P T + + +
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337
Query: 1191 RHPSMPAFPALLPAAPGHRGHETCPDDPCEDPGPTPPVQ------LAKNWTFPNTRAAGS 1244
H +P+ P A P + P + P P+PP + PN A
Sbjct: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHL 396
Query: 1245 SSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPSTS-DMAEEG 1303
P PP P +P A P + PS+ P+ PP +P S M+
Sbjct: 397 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 456
Query: 1304 RVASGGPPGL 1313
PP L
Sbjct: 457 TPPPQAPPPL 466
Score = 52.4 bits (124), Expect = 3e-06
Identities = 113/536 (21%), Positives = 165/536 (30%), Gaps = 87/536 (16%)
Query: 779 KSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRP-------- 830
K++ A R P + P G P P +P L V R
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPP--GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64
Query: 831 -GAPLVTKESPK--PDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKV 887
G + + +P+ P + PP + G + PGP G + +K
Sbjct: 65 IGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 124
Query: 888 MK-GIEENVLRLQGQE---RAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEG 943
++ EE V R + E R+ + R+TS + PA+ RR+ A + G
Sbjct: 125 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG-----TPSPAMARRSRAAGTEVG 179
Query: 944 AGGGSPLRREVKMEARKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPG 1003
+P R R E + +SS + P+P
Sbjct: 180 LPRPAPSARP-------------------------RPPTEGPRKSVSSASEHSTTEPSPA 214
Query: 1004 ----PNTGLGQVQGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSD 1059
P+ G G + + A + + P +P+ Q +
Sbjct: 215 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 274
Query: 1060 PKSPWPACGPRNGL---VGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACG 1116
+P PR +GPL PS+ P PS +L P T A
Sbjct: 275 QVTP-----PRKDAAPALGPLSSSPLATPSPSAPPSPSAP-PSLQTLPSPPATPPSQATT 328
Query: 1117 SL-TRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHT 1175
SL + TL + P P TP P PP L PP P PP + A
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATP----PPQAPPALALPPLQAPPSPPASPPLSPLATP 384
Query: 1176 LEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNWT 1235
+ + L+ P+ P P +P P P P TPP Q +
Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSP--------PASPPVSPSATPPSQAPPSLA 436
Query: 1236 FPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRP----SPTPQGPP 1287
P PL PP P +P A P + + P P PQ PP
Sbjct: 437 AP----------PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 80.1 bits (196), Expect = 1e-14
Identities = 228/1006 (22%), Positives = 342/1006 (33%), Gaps = 182/1006 (18%)
Query: 277 SRGPPQAQGTSSGPN--CAPGSSSSSSSDEAGDPNEAP--SPDTLLGALARRQLNLGQLL 332
S PP+ G P PG S S ++D + P SP T+ ++ + +L +
Sbjct: 89 SSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKE-- 146
Query: 333 EDTESYLQAFLA------GAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTP 386
E S + FL+ + +N +P S S K K + K G P
Sbjct: 147 EHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQ---GKP 203
Query: 387 EAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHS-SSQVKSKLQIGPPSPGEA- 444
E G Q P + G G PL + G P S SSQ K++ PP G+
Sbjct: 204 E----GIIKPPLQQQPPKPIPKQQGPGRDPL-QQDGTPKSISSQQPEKIKSQPPGTGKPI 258
Query: 445 QGPLLPSPARGLKFLKLP-------PTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSP 497
QGP + KLP P ++++ G + P LP S+ P + P
Sbjct: 259 QGP---TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ------P 309
Query: 498 SPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQ---LRPPQSALSTTLSP----GP 550
+P G E S G P PS T P + Q ++PP TT P GP
Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGL-TKPLAQQPGTVKPPVQPPGTTKPPAQPLGP 368
Query: 551 VVSPCYENILDLSRSTFRGP-----------SPEPPPSPLQVPTYP---------QLTLE 590
P + + S GP +P P P + PT Q L+
Sbjct: 369 AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428
Query: 591 VP-QAPEVLRSPGVPPSPCLPESYPYG----SPQEKSLDKAGSESPHPGR---RTPGNSS 642
P +AP ++P P P + G S Q+ K S+ P P + + PG +
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 643 KKPSQ-GSGRRPGD-PGST--------PLRDRLAALGKLKTG---PEGALGSEKNGVPAR 689
P Q GS + P PGST P + G K P A S + PA+
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548
Query: 690 PGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGA 749
P +++ P S + P P + G+ + N+ + L+ P
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL----LLHVPEK 604
Query: 750 RVYSS--HSMGARVDLEPVSPRSCLTKVE-------LAKSRLAGALCPQVPRTP------ 794
+++ L +P LT+V+ K L G L P VP +P
Sbjct: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP-VPSSPQPKLKT 663
Query: 795 ------AKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGP 848
+ V S+P + + ++P + SK+P P P T K K P
Sbjct: 664 APVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP 723
Query: 849 PWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAE 908
P AD S A P +PS E Q++AP A+
Sbjct: 724 PEADSLSKPAP-------PKEPSVPSE-------------------------QDKAPVAD 751
Query: 909 VKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNI 968
K + + K ++ + TK P K++++ E + +
Sbjct: 752 DKPKQPKMV-------KPTTDLVSSSSATTK---------PDIPSSKVQSQAEEKTTPPL 795
Query: 969 SKLMAKAEDLRRALEEEKAYLSSRARPRPGGPA-----PGPNT-GLGQVQGQLAGMYQGA 1022
AK E+ + S+A PRP + PGP++ GQ Q +
Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP 855
Query: 1023 DTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGK 1082
++ + D K +P S P P Q V + +SP P R + G
Sbjct: 856 KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN----LGS 911
Query: 1083 PPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSK 1142
P S+P +E + S F+ +L T G P G P K
Sbjct: 912 ITDAPKSQPTTPQETVTGKLFG--FGASIFSQASNLISTA----GQPGPHSQSGPGAPMK 965
Query: 1143 NLPKTKPPRLD--PPPGVPPARPPPLTKVPRRAHTLEREVPGIEEL 1186
P P PP A P P +P + T + P E+L
Sbjct: 966 QAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKET---KAPAAEKL 1008
Score = 79.0 bits (193), Expect = 3e-14
Identities = 189/824 (22%), Positives = 281/824 (34%), Gaps = 118/824 (14%)
Query: 114 SLPQIPLTPLQPPS--EPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPA 171
SLP P+Q P+ +PPA P P +G + +Q PG PP
Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ---PGTVKPPV 353
Query: 172 APP----PALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPING 227
PP P L P Q + E+ P L P + P Q PG +P
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413
Query: 228 ELCGPPQP---EPSPWAPCLLLGPGNLG------GLLHWERLLGGLGGEEDTGRPW---- 274
++ G P+P +P +P GP G + ++ G + TG
Sbjct: 414 QV-GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 275 --GPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLL 332
GP++ PPQ G + P PGS+ S P P G G
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ----PGSTKPPPQQPGPAKPSPQQPGSTK 528
Query: 333 EDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLP----------KSAWG 382
++ G+A P + P P + S+ P G P K
Sbjct: 529 PPSQQ------PGSAKP-SAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581
Query: 383 GGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPL------GSRPGHPHSSSQVKSKLQI 436
G P+ P T+E +P + F + G P +PH + +VK L +
Sbjct: 582 QGLPKTICP-LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP-NPHLT-EVKEWLCL 638
Query: 437 GPPSPGEAQGPLLPSPARGLKFLKLPP-TSEKSPSPGGPQLSPQLPRNSRIPCRN---SG 492
G L P P+ LK P T+ + S PQ P+ P ++ +
Sbjct: 639 NCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP 698
Query: 493 SDGSPSPLLARRGLGGGELSPEG-AQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPV 551
P PL+ + L G SP A+ P + S P P + + P
Sbjct: 699 EPKKPPPLVKQPTLHG---SPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPK 755
Query: 552 VSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPE 611
+ DL S+ P+ P S +Q + T L++ PS P
Sbjct: 756 QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT-------PPLKTDSAKPSQSFPP 808
Query: 612 SYPYGSP-QEKSLDKAGSESP---HPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAA 667
+ SP K++ + S+S HPG P + SK G++ DP + A
Sbjct: 809 TGEKVSPFDSKAIPRPASDSKIISHPG---PSSESK------GQKQVDPVQKKEEPKKA- 858
Query: 668 LGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHR-PLEQLEAK---- 722
+ K P+ G P PG T AG VP+ + P Q +++
Sbjct: 859 --QTKMSPKPDAKPMPKGSPTPPGPRPT---------AGQTVPTPQQSPKPQEQSRRFSL 907
Query: 723 --GGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKS 780
G I A + ++ G + GA ++S S +P P S
Sbjct: 908 NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP-GPHS---------Q 957
Query: 781 RLAGALCPQVPRTPAKVPTSA---PSLGKPNKSPHSS-PTKLPSKSPTKVVPRPGAPLVT 836
GA Q P P++ PTS S G+ +P S P K +K+P P A
Sbjct: 958 SGPGAPMKQAP-APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016
Query: 837 KESPKPDKGKGPPWADCGSTTAQ-STPLVPGPTDPSQGPEGLAP 879
+ K PP D S TA+ ++P + S PE P
Sbjct: 1017 TVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Score = 48.5 bits (114), Expect = 4e-05
Identities = 77/335 (22%), Positives = 104/335 (31%), Gaps = 75/335 (22%)
Query: 1044 REPKPEYGDFQPVSSDP--KSPWPACGPRNGLVG-------PLQGCGKPPGK-------- 1086
+ P + G +P++ P +SP A GP V P Q G PGK
Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG--PGKTSAQQTGP 466
Query: 1087 ---PSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKN 1143
PS PG + P + A+P P GS T PPP PS
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQP----GSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522
Query: 1144 LP-KTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELL------VSGRHPSMP 1196
P TKPP P P A+ P K + T G + L S + P
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
Query: 1197 AFP----------ALLPAAPGHRGHETCPDDPCEDP-------GPTPPVQLAKNWTFPN- 1238
P LL P TC + C+ P P + K W N
Sbjct: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTE--CQTTVCSLCGFNPNPHLTEVKEWLCLNC 640
Query: 1239 --TRAAGSSSDPL--------------------MCPPRQLEGLPRTPMALPVDRKRSQEP 1276
RA G P+ P+ + P+ A D ++ EP
Sbjct: 641 QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700
Query: 1277 SRPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGPP 1311
+P P + P GS + E ++ PP
Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP 735
Score = 41.6 bits (96), Expect = 0.005
Identities = 73/274 (26%), Positives = 96/274 (35%), Gaps = 39/274 (14%)
Query: 1047 KPEYGDFQPVSSDPKSPWPAC-GPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAE 1105
KPE P+ P P P GP PLQ G P S +P + + P
Sbjct: 202 KPEGIIKPPLQQQPPKPIPKQQGPGRD---PLQQDGTPKSISSQQPEKIKSQPPGTGKPI 258
Query: 1106 PVPT-SHFTACGSLTRTLDSGIGTFPPPD--HGSSGTPSKNLPKTKPPRLDPPPGVPPAR 1162
PT + T L D+ D G S PS P +KPP P PG PPA+
Sbjct: 259 QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP-SKPPIQQPTPGKPPAQ 317
Query: 1163 PPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPA-FPALLPAAPGHRGHETCPDDPCED 1221
P H E+ PG + P+ P+ L PG P +
Sbjct: 318 QP--------GH--EKSQPG------PAKPPAQPSGLTKPLAQQPG------TVKPPVQP 355
Query: 1222 PGPTPPVQLAKNWTFPNTRAAG----SSSDPLMCPPRQLEGLPRTPMALPVDRK-RSQEP 1276
PG T P P + G SS P Q G+ +TP P K +Q+
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 1277 SRPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGP 1310
P P Q P G ++P+ + + V GP
Sbjct: 416 GTPKPLAQQP---GLQSPAKAPGPTKTPVQQPGP 446
Score = 40.0 bits (92), Expect = 0.015
Identities = 118/566 (20%), Positives = 179/566 (31%), Gaps = 100/566 (17%)
Query: 122 PLQPPSEPPASPSLSSTEGPAAP-LPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDAL 180
P QP P + +SS+ P +P Q E L+ P + PP + +
Sbjct: 754 PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV 813
Query: 181 SPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSP-----EPINGELCGPPQP 235
SPF K +D ++ P GQ P EP + P+P
Sbjct: 814 SPFDSKAIP-------RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKP 866
Query: 236 EPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPG 295
+ P G P P P Q T P +P
Sbjct: 867 DAKPMPK----------------------------GSPTPPGPRPTAGQ-TVPTPQQSPK 897
Query: 296 SSSSSS--SDEAGDPNEAPS--PDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLN 351
S S G +AP P T + + G + S L + AG GP +
Sbjct: 898 PQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS-TAGQPGPHS 956
Query: 352 GDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMG 411
PG +P AP Q S+G PKS G P A E + P
Sbjct: 957 QSGPGAPMKQAP--APSQPPTSQGPPKST--GQAPPAPAKSIPVKKETKAP--------- 1003
Query: 412 AGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSP 471
A P + + +++ + PP P + L P + + LP EKSP P
Sbjct: 1004 ---AAEKLEPKAEQAPTVKRTETEKKPP-PIKDSKSLTAEPQKAV----LPTKLEKSPKP 1055
Query: 472 GG--PQLSPQLPRNSRIP--------CRNSGSD---GSPSPLL------------ARRGL 506
P +L S+ P C+N + +P+P L +R +
Sbjct: 1056 ESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAI 1115
Query: 507 GG--GEL--SPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDL 562
G G++ P G SP P T S + P V + + IL+
Sbjct: 1116 SGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEK 1175
Query: 563 SRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVP-PSPCLPESYPYGSPQEK 621
+ T + PP + LE +A + +P +PE S ++K
Sbjct: 1176 VKETL--SMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKK 1233
Query: 622 SLDKAGSESPHPGRRTPGNSSKKPSQ 647
L + +P + P + P +
Sbjct: 1234 PLLEEKKPTPEDKKLLPEAKTSAPEE 1259
Score = 33.1 bits (74), Expect = 1.8
Identities = 52/228 (22%), Positives = 74/228 (32%), Gaps = 45/228 (19%)
Query: 1120 RTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLERE 1179
R+ I PPP P P PP PPP +PP P T +P++ T+
Sbjct: 2395 RSSSLDISAQPPPP------PPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448
Query: 1180 VPGIEEL----------------------LVSGRHPSMPAFPALLPAAPGHRGHETCPDD 1217
V L + + P +P P+ +P+ H P
Sbjct: 2449 VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFT-HRPEPSK 2507
Query: 1218 PCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPS 1277
P P P P P T + P + GL T ++ ++ S +
Sbjct: 2508 PPIAPKPVIP-------QLPTTTQKPTDIHP------KPTGLSLT-SSMTLNLVTSADYK 2553
Query: 1278 RPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGP--PGLETSESLSDSL 1323
PSPT P +P S E V P PG T S S ++
Sbjct: 2554 LPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAI 2601
Score = 33.1 bits (74), Expect = 1.8
Identities = 46/210 (21%), Positives = 80/210 (38%), Gaps = 26/210 (12%)
Query: 786 LCPQVPRTPAKV--PTSAPSLGKPNKS---PHSSPTKLPSK-SPTKVVPRPGAPLVTKES 839
L P P++P + P S S GK +S P+ P LP SP KV+
Sbjct: 3612 LAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKP--LPDDISPQKVL------------ 3657
Query: 840 PKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQ 899
PD K PP + + Q + P P P+ AP E KG +
Sbjct: 3658 -HPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKG--SQTMTSS 3714
Query: 900 GQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGAGGGSPLRREVKMEAR 959
G ++ + + I++ S + ++RR N + + +++ E
Sbjct: 3715 GAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMAR---AKILQDIDRELD 3771
Query: 960 KLEAESLNISKLMAKAEDLRRALEEEKAYL 989
+E ES + K A+ ++ + ++ + YL
Sbjct: 3772 LVERESAKLRKKQAELDEEEKEIDAKLRYL 3801
Score = 32.3 bits (72), Expect = 3.1
Identities = 40/149 (26%), Positives = 49/149 (32%), Gaps = 39/149 (26%)
Query: 104 FQQKLQLTTGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLR 163
F + L + P P P PP PP P P PLP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPPP-------PPPPLP----------------P 2429
Query: 164 PGGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPL--------LLCSPATPWRPP 215
P P P P L SP + + + + LE T L +C+ A P PP
Sbjct: 2430 PTSPKPTILPKKKLTVASP-VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP 2488
Query: 216 GQGPGSPEPINGELCGPPQPEPS--PWAP 242
P I L +PEPS P AP
Sbjct: 2489 -----KPSSIPSGLVFTHRPEPSKPPIAP 2512
Score = 31.2 bits (69), Expect = 7.0
Identities = 44/202 (21%), Positives = 64/202 (31%), Gaps = 36/202 (17%)
Query: 1130 PPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELL-V 1188
P D + P K P K P L P +PP + + A E VP ++ V
Sbjct: 690 PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV 749
Query: 1189 SGRHPSMPAFPALLPAAPGHRGHETCPDDPCE------DPGPTPPVQ---LAKNWTFPNT 1239
+ P P T PD P + TPP++ + +FP T
Sbjct: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT 809
Query: 1240 RAAGSSSDPLMCP--------------------PRQLEGLPRTPMALPVDRKRSQEPS-- 1277
S D P +Q++ + + K S +P
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK 869
Query: 1278 ---RPSPTPQGP-PFGGSRTPS 1295
+ SPTP GP P G P+
Sbjct: 870 PMPKGSPTPPGPRPTAGQTVPT 891
Score = 30.8 bits (68), Expect = 9.1
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 570 PSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSP 607
P P PPP PL PT P+ T+ +P+ + SP +P
Sbjct: 2418 PPPPPPPPPLPPPTSPKPTI-LPKKKLTVASPVTTATP 2454
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 80.1 bits (196), Expect = 1e-14
Identities = 228/1006 (22%), Positives = 342/1006 (33%), Gaps = 182/1006 (18%)
Query: 277 SRGPPQAQGTSSGPN--CAPGSSSSSSSDEAGDPNEAP--SPDTLLGALARRQLNLGQLL 332
S PP+ G P PG S S ++D + P SP T+ ++ + +L +
Sbjct: 89 SSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKE-- 146
Query: 333 EDTESYLQAFLA------GAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTP 386
E S + FL+ + +N +P S S K K + K G P
Sbjct: 147 EHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQ---GKP 203
Query: 387 EAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHS-SSQVKSKLQIGPPSPGEA- 444
E G Q P + G G PL + G P S SSQ K++ PP G+
Sbjct: 204 E----GIIKPPLQQQPPKPIPKQQGPGRDPL-QQDGTPKSISSQQPEKIKSQPPGTGKPI 258
Query: 445 QGPLLPSPARGLKFLKLP-------PTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSP 497
QGP + KLP P ++++ G + P LP S+ P + P
Sbjct: 259 QGP---TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ------P 309
Query: 498 SPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQ---LRPPQSALSTTLSP----GP 550
+P G E S G P PS T P + Q ++PP TT P GP
Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGL-TKPLAQQPGTVKPPVQPPGTTKPPAQPLGP 368
Query: 551 VVSPCYENILDLSRSTFRGP-----------SPEPPPSPLQVPTYP---------QLTLE 590
P + + S GP +P P P + PT Q L+
Sbjct: 369 AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428
Query: 591 VP-QAPEVLRSPGVPPSPCLPESYPYG----SPQEKSLDKAGSESPHPGR---RTPGNSS 642
P +AP ++P P P + G S Q+ K S+ P P + + PG +
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 643 KKPSQ-GSGRRPGD-PGST--------PLRDRLAALGKLKTG---PEGALGSEKNGVPAR 689
P Q GS + P PGST P + G K P A S + PA+
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548
Query: 690 PGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGA 749
P +++ P S + P P + G+ + N+ + L+ P
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL----LLHVPEK 604
Query: 750 RVYSS--HSMGARVDLEPVSPRSCLTKVE-------LAKSRLAGALCPQVPRTP------ 794
+++ L +P LT+V+ K L G L P VP +P
Sbjct: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP-VPSSPQPKLKT 663
Query: 795 ------AKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGP 848
+ V S+P + + ++P + SK+P P P T K K P
Sbjct: 664 APVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP 723
Query: 849 PWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAE 908
P AD S A P +PS E Q++AP A+
Sbjct: 724 PEADSLSKPAP-------PKEPSVPSE-------------------------QDKAPVAD 751
Query: 909 VKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNI 968
K + + K ++ + TK P K++++ E + +
Sbjct: 752 DKPKQPKMV-------KPTTDLVSSSSATTK---------PDIPSSKVQSQAEEKTTPPL 795
Query: 969 SKLMAKAEDLRRALEEEKAYLSSRARPRPGGPA-----PGPNT-GLGQVQGQLAGMYQGA 1022
AK E+ + S+A PRP + PGP++ GQ Q +
Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP 855
Query: 1023 DTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGK 1082
++ + D K +P S P P Q V + +SP P R + G
Sbjct: 856 KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN----LGS 911
Query: 1083 PPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSK 1142
P S+P +E + S F+ +L T G P G P K
Sbjct: 912 ITDAPKSQPTTPQETVTGKLFG--FGASIFSQASNLISTA----GQPGPHSQSGPGAPMK 965
Query: 1143 NLPKTKPPRLD--PPPGVPPARPPPLTKVPRRAHTLEREVPGIEEL 1186
P P PP A P P +P + T + P E+L
Sbjct: 966 QAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKET---KAPAAEKL 1008
Score = 79.0 bits (193), Expect = 3e-14
Identities = 189/824 (22%), Positives = 281/824 (34%), Gaps = 118/824 (14%)
Query: 114 SLPQIPLTPLQPPS--EPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPA 171
SLP P+Q P+ +PPA P P +G + +Q PG PP
Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ---PGTVKPPV 353
Query: 172 APP----PALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPING 227
PP P L P Q + E+ P L P + P Q PG +P
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413
Query: 228 ELCGPPQP---EPSPWAPCLLLGPGNLG------GLLHWERLLGGLGGEEDTGRPW---- 274
++ G P+P +P +P GP G + ++ G + TG
Sbjct: 414 QV-GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 275 --GPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLL 332
GP++ PPQ G + P PGS+ S P P G G
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ----PGSTKPPPQQPGPAKPSPQQPGSTK 528
Query: 333 EDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLP----------KSAWG 382
++ G+A P + P P + S+ P G P K
Sbjct: 529 PPSQQ------PGSAKP-SAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581
Query: 383 GGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPL------GSRPGHPHSSSQVKSKLQI 436
G P+ P T+E +P + F + G P +PH + +VK L +
Sbjct: 582 QGLPKTICP-LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP-NPHLT-EVKEWLCL 638
Query: 437 GPPSPGEAQGPLLPSPARGLKFLKLPP-TSEKSPSPGGPQLSPQLPRNSRIPCRN---SG 492
G L P P+ LK P T+ + S PQ P+ P ++ +
Sbjct: 639 NCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP 698
Query: 493 SDGSPSPLLARRGLGGGELSPEG-AQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPV 551
P PL+ + L G SP A+ P + S P P + + P
Sbjct: 699 EPKKPPPLVKQPTLHG---SPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPK 755
Query: 552 VSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPE 611
+ DL S+ P+ P S +Q + T L++ PS P
Sbjct: 756 QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT-------PPLKTDSAKPSQSFPP 808
Query: 612 SYPYGSP-QEKSLDKAGSESP---HPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAA 667
+ SP K++ + S+S HPG P + SK G++ DP + A
Sbjct: 809 TGEKVSPFDSKAIPRPASDSKIISHPG---PSSESK------GQKQVDPVQKKEEPKKA- 858
Query: 668 LGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHR-PLEQLEAK---- 722
+ K P+ G P PG T AG VP+ + P Q +++
Sbjct: 859 --QTKMSPKPDAKPMPKGSPTPPGPRPT---------AGQTVPTPQQSPKPQEQSRRFSL 907
Query: 723 --GGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKS 780
G I A + ++ G + GA ++S S +P P S
Sbjct: 908 NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP-GPHS---------Q 957
Query: 781 RLAGALCPQVPRTPAKVPTSA---PSLGKPNKSPHSS-PTKLPSKSPTKVVPRPGAPLVT 836
GA Q P P++ PTS S G+ +P S P K +K+P P A
Sbjct: 958 SGPGAPMKQAP-APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016
Query: 837 KESPKPDKGKGPPWADCGSTTAQ-STPLVPGPTDPSQGPEGLAP 879
+ K PP D S TA+ ++P + S PE P
Sbjct: 1017 TVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Score = 48.5 bits (114), Expect = 4e-05
Identities = 77/335 (22%), Positives = 104/335 (31%), Gaps = 75/335 (22%)
Query: 1044 REPKPEYGDFQPVSSDP--KSPWPACGPRNGLVG-------PLQGCGKPPGK-------- 1086
+ P + G +P++ P +SP A GP V P Q G PGK
Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG--PGKTSAQQTGP 466
Query: 1087 ---PSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKN 1143
PS PG + P + A+P P GS T PPP PS
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKPPPQQP----GSAKPPSQQPGSTKPPPQQPGPAKPSPQ 522
Query: 1144 LP-KTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELL------VSGRHPSMP 1196
P TKPP P P A+ P K + T G + L S + P
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
Query: 1197 AFP----------ALLPAAPGHRGHETCPDDPCEDP-------GPTPPVQLAKNWTFPN- 1238
P LL P TC + C+ P P + K W N
Sbjct: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTE--CQTTVCSLCGFNPNPHLTEVKEWLCLNC 640
Query: 1239 --TRAAGSSSDPL--------------------MCPPRQLEGLPRTPMALPVDRKRSQEP 1276
RA G P+ P+ + P+ A D ++ EP
Sbjct: 641 QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700
Query: 1277 SRPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGPP 1311
+P P + P GS + E ++ PP
Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP 735
Score = 41.6 bits (96), Expect = 0.005
Identities = 73/274 (26%), Positives = 96/274 (35%), Gaps = 39/274 (14%)
Query: 1047 KPEYGDFQPVSSDPKSPWPAC-GPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAE 1105
KPE P+ P P P GP PLQ G P S +P + + P
Sbjct: 202 KPEGIIKPPLQQQPPKPIPKQQGPGRD---PLQQDGTPKSISSQQPEKIKSQPPGTGKPI 258
Query: 1106 PVPT-SHFTACGSLTRTLDSGIGTFPPPD--HGSSGTPSKNLPKTKPPRLDPPPGVPPAR 1162
PT + T L D+ D G S PS P +KPP P PG PPA+
Sbjct: 259 QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP-SKPPIQQPTPGKPPAQ 317
Query: 1163 PPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPA-FPALLPAAPGHRGHETCPDDPCED 1221
P H E+ PG + P+ P+ L PG P +
Sbjct: 318 QP--------GH--EKSQPG------PAKPPAQPSGLTKPLAQQPG------TVKPPVQP 355
Query: 1222 PGPTPPVQLAKNWTFPNTRAAG----SSSDPLMCPPRQLEGLPRTPMALPVDRK-RSQEP 1276
PG T P P + G SS P Q G+ +TP P K +Q+
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 1277 SRPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGP 1310
P P Q P G ++P+ + + V GP
Sbjct: 416 GTPKPLAQQP---GLQSPAKAPGPTKTPVQQPGP 446
Score = 40.0 bits (92), Expect = 0.015
Identities = 118/566 (20%), Positives = 179/566 (31%), Gaps = 100/566 (17%)
Query: 122 PLQPPSEPPASPSLSSTEGPAAP-LPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDAL 180
P QP P + +SS+ P +P Q E L+ P + PP + +
Sbjct: 754 PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV 813
Query: 181 SPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSP-----EPINGELCGPPQP 235
SPF K +D ++ P GQ P EP + P+P
Sbjct: 814 SPFDSKAIP-------RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKP 866
Query: 236 EPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPG 295
+ P G P P P Q T P +P
Sbjct: 867 DAKPMPK----------------------------GSPTPPGPRPTAGQ-TVPTPQQSPK 897
Query: 296 SSSSSS--SDEAGDPNEAPS--PDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLN 351
S S G +AP P T + + G + S L + AG GP +
Sbjct: 898 PQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS-TAGQPGPHS 956
Query: 352 GDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMG 411
PG +P AP Q S+G PKS G P A E + P
Sbjct: 957 QSGPGAPMKQAP--APSQPPTSQGPPKST--GQAPPAPAKSIPVKKETKAP--------- 1003
Query: 412 AGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSP 471
A P + + +++ + PP P + L P + + LP EKSP P
Sbjct: 1004 ---AAEKLEPKAEQAPTVKRTETEKKPP-PIKDSKSLTAEPQKAV----LPTKLEKSPKP 1055
Query: 472 GG--PQLSPQLPRNSRIP--------CRNSGSD---GSPSPLL------------ARRGL 506
P +L S+ P C+N + +P+P L +R +
Sbjct: 1056 ESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAI 1115
Query: 507 GG--GEL--SPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDL 562
G G++ P G SP P T S + P V + + IL+
Sbjct: 1116 SGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEK 1175
Query: 563 SRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVP-PSPCLPESYPYGSPQEK 621
+ T + PP + LE +A + +P +PE S ++K
Sbjct: 1176 VKETL--SMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKK 1233
Query: 622 SLDKAGSESPHPGRRTPGNSSKKPSQ 647
L + +P + P + P +
Sbjct: 1234 PLLEEKKPTPEDKKLLPEAKTSAPEE 1259
Score = 33.1 bits (74), Expect = 1.8
Identities = 52/228 (22%), Positives = 74/228 (32%), Gaps = 45/228 (19%)
Query: 1120 RTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLERE 1179
R+ I PPP P P PP PPP +PP P T +P++ T+
Sbjct: 2395 RSSSLDISAQPPPP------PPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448
Query: 1180 VPGIEEL----------------------LVSGRHPSMPAFPALLPAAPGHRGHETCPDD 1217
V L + + P +P P+ +P+ H P
Sbjct: 2449 VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFT-HRPEPSK 2507
Query: 1218 PCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPS 1277
P P P P P T + P + GL T ++ ++ S +
Sbjct: 2508 PPIAPKPVIP-------QLPTTTQKPTDIHP------KPTGLSLT-SSMTLNLVTSADYK 2553
Query: 1278 RPSPTPQGPPFGGSRTPSTSDMAEEGRVASGGP--PGLETSESLSDSL 1323
PSPT P +P S E V P PG T S S ++
Sbjct: 2554 LPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAI 2601
Score = 33.1 bits (74), Expect = 1.8
Identities = 46/210 (21%), Positives = 80/210 (38%), Gaps = 26/210 (12%)
Query: 786 LCPQVPRTPAKV--PTSAPSLGKPNKS---PHSSPTKLPSK-SPTKVVPRPGAPLVTKES 839
L P P++P + P S S GK +S P+ P LP SP KV+
Sbjct: 3612 LAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKP--LPDDISPQKVL------------ 3657
Query: 840 PKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQ 899
PD K PP + + Q + P P P+ AP E KG +
Sbjct: 3658 -HPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKG--SQTMTSS 3714
Query: 900 GQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGAGGGSPLRREVKMEAR 959
G ++ + + I++ S + ++RR N + + +++ E
Sbjct: 3715 GAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMAR---AKILQDIDRELD 3771
Query: 960 KLEAESLNISKLMAKAEDLRRALEEEKAYL 989
+E ES + K A+ ++ + ++ + YL
Sbjct: 3772 LVERESAKLRKKQAELDEEEKEIDAKLRYL 3801
Score = 32.3 bits (72), Expect = 3.1
Identities = 40/149 (26%), Positives = 49/149 (32%), Gaps = 39/149 (26%)
Query: 104 FQQKLQLTTGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLR 163
F + L + P P P PP PP P P PLP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPPP-------PPPPLP----------------P 2429
Query: 164 PGGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPL--------LLCSPATPWRPP 215
P P P P L SP + + + + LE T L +C+ A P PP
Sbjct: 2430 PTSPKPTILPKKKLTVASP-VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP 2488
Query: 216 GQGPGSPEPINGELCGPPQPEPS--PWAP 242
P I L +PEPS P AP
Sbjct: 2489 -----KPSSIPSGLVFTHRPEPSKPPIAP 2512
Score = 31.2 bits (69), Expect = 7.0
Identities = 44/202 (21%), Positives = 64/202 (31%), Gaps = 36/202 (17%)
Query: 1130 PPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELL-V 1188
P D + P K P K P L P +PP + + A E VP ++ V
Sbjct: 690 PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV 749
Query: 1189 SGRHPSMPAFPALLPAAPGHRGHETCPDDPCE------DPGPTPPVQ---LAKNWTFPNT 1239
+ P P T PD P + TPP++ + +FP T
Sbjct: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT 809
Query: 1240 RAAGSSSDPLMCP--------------------PRQLEGLPRTPMALPVDRKRSQEPS-- 1277
S D P +Q++ + + K S +P
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK 869
Query: 1278 ---RPSPTPQGP-PFGGSRTPS 1295
+ SPTP GP P G P+
Sbjct: 870 PMPKGSPTPPGPRPTAGQTVPT 891
Score = 30.8 bits (68), Expect = 9.1
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 570 PSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSP 607
P P PPP PL PT P+ T+ +P+ + SP +P
Sbjct: 2418 PPPPPPPPPLPPPTSPKPTI-LPKKKLTVASPVTTATP 2454
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 79.7 bits (195), Expect = 2e-14
Identities = 166/703 (23%), Positives = 223/703 (31%), Gaps = 160/703 (22%)
Query: 207 SPATPWRPPGQGPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGG 266
+P P +P G P G + PQ EP P PG G G
Sbjct: 671 TPGAPGQPGMAGVDGPPGPKGNM--GPQGEPGP--------PGQQGN-----------PG 709
Query: 267 EEDTGRPWGPSRGPPQAQGTSSGPNCA-----------PGSSSSSSSDEA-GDPNEA--- 311
+ P GP GPP +G P A PG S A G P
Sbjct: 710 PQGLPGPQGPI-GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI 768
Query: 312 --PSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQ 369
P P + GA R L G E E F G G L GD GQ + P+
Sbjct: 769 GYPGPRGVKGADGVRGLK-GSKGEKGEDGFPGF-KGDMG-LKGDRGEVGQIGPRGEDGPE 825
Query: 370 LSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSR--PGHPHSS 427
K + P G P A +G+ +P L + G P GS PG P ++
Sbjct: 826 GPKGRAGPTGDPG--------PSGQAGEKGKLGVPGLPGYPGR-QGPKGSTGFPGFPGAN 876
Query: 428 SQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIP 487
+ ++ G P P +GP P +RG + PT + P P P R P
Sbjct: 877 GEKGARGVAGKPGPRGQRGPTGPRGSRGAR----GPTGKPGPKGTSGGDGPPGPPGERGP 932
Query: 488 CRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLS 547
G G P P G P G GLP P T + PP
Sbjct: 933 QGPQGPVGFPGPK--------GPPGPPGKDGLPGHPGQRGETGFQGKTGPP--------G 976
Query: 548 PGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSP 607
PG VV P +GP+ E P + P PG P
Sbjct: 977 PGGVVGP-------------QGPTGETGPIGERGHPGP---------------PGPPGEQ 1008
Query: 608 CLP----ESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRD 663
LP + G P + + +G + P R PG +QG+ PG G
Sbjct: 1009 GLPGAAGKEGAKGDPGPQGI--SGKDGPAGLRGFPGERGLPGAQGA---PGLKG------ 1057
Query: 664 RLAALGKLKTGPEGALGSEKN----------GVPARPGTEKTRGPGKSGESAGDMVPSIH 713
G+ GP G +GS G+P RPG + GP + G+ P
Sbjct: 1058 -----GEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1112
Query: 714 RPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLT 773
+ ++ G+ G + + + G +G+PG + S G + + P P
Sbjct: 1113 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQK----GSKGDKGENGPPGPPGL-- 1166
Query: 774 KVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAP 833
+ P P A G+P + P P P
Sbjct: 1167 ------------------QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1208
Query: 834 LVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEG 876
+ + P P KG + G P PGP P QGP G
Sbjct: 1209 IGLQGLPGPPGEKG----ENGDVGPMGPPGPPGPRGP-QGPNG 1246
Score = 78.6 bits (192), Expect = 4e-14
Identities = 203/836 (24%), Positives = 268/836 (32%), Gaps = 125/836 (14%)
Query: 130 PASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDALSPFLRKKAQ 189
P P ++ +GP P P G+ Q E Q G PGP P P + P K Q
Sbjct: 675 PGQPGMAGVDGP--PGPKGNMGPQGEPGPPGQ--QGNPGPQGLPGPQ-GPIGPPGEKGPQ 729
Query: 190 ILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGE--LCGPPQPEPSPWAPCLLLG 247
L L D PPG PG E +GE GPP P+ P G
Sbjct: 730 GKPGLAGLPGADG-----------PPGH-PGK-EGQSGEKGALGPPGPQ----GPIGYPG 772
Query: 248 PGNLGGLLHWERLLGGLGGEEDTGRPWGPS-------RGP-----PQAQGTSSGPNCAPG 295
P + G L G G + + G P RG P+ + GP G
Sbjct: 773 PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 832
Query: 296 SSSSSS-SDEAGDPNEAPSPDTLLGALARRQLNLGQLL------EDTESYLQAFLAGAAG 348
+ S +AG+ + P L RQ G + E + +AG G
Sbjct: 833 PTGDPGPSGQAGEKGKLGVPG--LPGYPGRQGPKGSTGFPGFPGANGEKGARG-VAGKPG 889
Query: 349 PLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSM 408
P P + S + P K PK GG P PG QGP+ F
Sbjct: 890 PRGQRGPTGPRGSRGARGPT----GKPGPKGTSGGDGPPGP-PGERGPQGPQGPVGFPGP 944
Query: 409 FMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKS 468
G PGHP + + + GPP PG GP P+ G P E+
Sbjct: 945 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG-------PIGERG 997
Query: 469 -PSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCY 527
P P GP LP G+ G P P +G+ G + P G +G P
Sbjct: 998 HPGPPGPPGEQGLPG----AAGKEGAKGDPGP----QGISGKD-GPAGLRGFPGERG--- 1045
Query: 528 TTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSR--STFRGPSPEPPPSPLQVPTYP 585
P + + PGPV SP + P P+ PP P P
Sbjct: 1046 -LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1104
Query: 586 -QLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKK 644
+ + P + ++ P P P + P GSP G + PG K
Sbjct: 1105 GEKGPQGPAGRDGVQGPVGLPGP----AGPAGSP--------GEDGDKGEIGEPGQKGSK 1152
Query: 645 PSQGSGRRPGDPG-STPLRDRLAALGKLKTGPEGALG-------SEKNGVPARPGTEKTR 696
+G PG PG P+ A G + GP G G G P PG +
Sbjct: 1153 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1212
Query: 697 G----PGKSGESAGDM-------VPSIHRPLEQLEAKG--GIRGAVALGTNSLKQQEPGL 743
G PG+ GE+ GD+ P P A G G G+V ++ EPG
Sbjct: 1213 GLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1271
Query: 744 MGDPG--ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSA 801
G+PG G R + P G P+ P P
Sbjct: 1272 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP--GAKGPPGDDGPKGNPGPVGFPGDP 1329
Query: 802 PSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWA---------- 851
G+P + + P P P P P +GPP A
Sbjct: 1330 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1389
Query: 852 -DCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPG 906
G A+ P GP P QGP G + E+ + GQ+ PG
Sbjct: 1390 GAKGEAGAEGPPGKTGPVGP-QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1444
Score = 72.0 bits (175), Expect = 4e-12
Identities = 194/790 (24%), Positives = 241/790 (30%), Gaps = 185/790 (23%)
Query: 208 PATPWRPPG-QGPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGG 266
PA PPG QGP P G+ GPP P A L PG G +L GG G
Sbjct: 461 PAGIMGPPGLQGPTGPPGDPGDR-GPPGRPGLPGADGL---PGPPGTMLMLPFRYGGDGS 516
Query: 267 EEDTGRPWGPS------------RGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNE---- 310
+ T RGPP G + P G SS + E+GDP
Sbjct: 517 KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPR 576
Query: 311 ----APSPDTLLGALARRQLNLGQ-------------------LLEDTESYLQAFLAGAA 347
P P G R + G+ L D + G
Sbjct: 577 GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 636
Query: 348 GP-----LNGDHPGPGQSSSPDQAPPQ-------LSKSKGLPKSAWGGGTP--------- 386
GP + G+ G P +A P+ + G P A G P
Sbjct: 637 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 696
Query: 387 -------EAHRPGFGATSEGQGPL-----------PFLSMFMGAGDAPLGSRPGHPHSSS 428
+ PG QGP+ P L+ GA D P PGHP
Sbjct: 697 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA-DGP----PGHPGKEG 751
Query: 429 QVKSKLQIGPPSPGEAQGPL-LPSP--------ARGLKFLKLPPTSEKSPSPGGP----- 474
Q K +GPP P QGP+ P P RGLK K + P G
Sbjct: 752 QSGEKGALGPPGP---QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 808
Query: 475 ------QLSPQLPRNSRIPCRNSGSDGSPSP--------LLARRGLGG--GELSPEGAQG 518
Q+ P+ P +G G P P L GL G G P+G+ G
Sbjct: 809 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 868
Query: 519 LPTSPSP--------CYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGP 570
P P P R P + + GP P + T G
Sbjct: 869 FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG-------PKGTSGGD 921
Query: 571 SPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSES 630
P PP + + PQ P P PP P + P
Sbjct: 922 GPPGPPG--------ERGPQGPQGPVGFPGPKGPPGPPGKDGLP---------------- 957
Query: 631 PHPGRR-TPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVPAR 689
HPG+R G K G G G G T + G GP G G + G+P
Sbjct: 958 GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG--HPGPPGPPGEQ--GLPGA 1013
Query: 690 PGTEKTRG-PGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPG 748
G E +G PG G S D P+ R G +GA L Q PG +G PG
Sbjct: 1014 AGKEGAKGDPGPQGISGKD-GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1072
Query: 749 ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVP--RTPAKVPTSAPSLGK 806
R S + L P P + G PQ P R + P P
Sbjct: 1073 ER--GSAGTAGPIGL-PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1129
Query: 807 PNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPG 866
P SP K + PG ++ K DKG+ P G P + G
Sbjct: 1130 PAGSPGEDGDK-------GEIGEPG-----QKGSKGDKGENGPPGPPGLQGPVGAPGIAG 1177
Query: 867 PTDPSQGPEG 876
D GP G
Sbjct: 1178 -GDGEPGPRG 1186
Score = 68.2 bits (165), Expect = 5e-11
Identities = 177/721 (24%), Positives = 225/721 (31%), Gaps = 180/721 (24%)
Query: 211 PWRPPG----QGPGSPEPINGELC--GPPQPEPSPWAPCLL--------LGPGNLGGLLH 256
P PPG QGP P G GPP + P P GP GG++
Sbjct: 923 PPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG 982
Query: 257 WERLLGGLGGEEDTGRPWGPSRGPPQAQGT-----SSGPNCAPGSSSSSSSDEAGDPNEA 311
+ G G + G P P GPP QG G PG S D
Sbjct: 983 PQGPTGETGPIGERGHPGPP--GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 1040
Query: 312 PSPDTLLGALARRQLNLGQLLEDTESYL----QAFLAGAAGPLN-GDHPGPGQSSSPDQA 366
P L GA L G+ + + + AG AGP+ PGP Q
Sbjct: 1041 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP-------QG 1093
Query: 367 PPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAG----DAPLGSRPG 422
PP + KG P G A R G QGP+ AG D G G
Sbjct: 1094 PPGPAGEKGAPGEK--GPQGPAGRDGV------QGPVGLPGPAGPAGSPGEDGDKGEI-G 1144
Query: 423 HPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPR 482
P K + GPP P QGP+ G P ++
Sbjct: 1145 EPGQKGSKGDKGENGPPGPPGLQGPV-----------------------GAPGIA----- 1176
Query: 483 NSRIPCRNSGSDGSPSPLLARRGLGG--GELSPEGAQGLPTSPSPCYTTPDSTQLRPPQS 540
G DG P P RG G G+ EGA+G P P P L P
Sbjct: 1177 ---------GGDGEPGP----RGQQGMFGQKGDEGARGFPGPPGPI----GLQGLPGPPG 1219
Query: 541 ALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSP--LQVPTYPQLTLEVPQAPEVL 598
GP+ P P P P P P P ++
Sbjct: 1220 EKGENGDVGPMGPP-------------GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266
Query: 599 RSPGVPPSPCLPESYPYGSPQEKSLDKA-----GSESPHPGRRTPGNSSKKPSQGSGRRP 653
PG +P P G P+ + +K G+ P + PG+ K + G P
Sbjct: 1267 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1326
Query: 654 GDPGSTPLRDRLAALGKLKTGPEG--ALGSEK--NGVPARPGTEKTRGPGKSGESAGDMV 709
GDPG + GP G +G +K +G P +PG PG SGE+
Sbjct: 1327 GDPGPPG-----------EPGPAGQDGVGGDKGEDGDPGQPGP-----PGPSGEAGPPGP 1370
Query: 710 PSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPR 769
P P A+G +Q E G G+ GA G PV P+
Sbjct: 1371 PGKRGPPGAAGAEG-------------RQGEKGAKGEAGAE-------GPPGKTGPVGPQ 1410
Query: 770 SCLTKV----------ELAKSRLAGALCPQVPRTPAKVPTSAPSLGKP-NKSPHSSPTKL 818
K + + L GA P P P G P +K P +
Sbjct: 1411 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1470
Query: 819 PSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDP--SQGPEG 876
P PG ++ K D+G GS A+ +PGP P GP G
Sbjct: 1471 GLIGP------PG-----EQGEKGDRGLP---GTQGSPGAKGDGGIPGPAGPLGPPGPPG 1516
Query: 877 L 877
L
Sbjct: 1517 L 1517
Score = 57.0 bits (136), Expect = 1e-07
Identities = 147/580 (25%), Positives = 180/580 (31%), Gaps = 117/580 (20%)
Query: 110 LTTGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGP-- 167
L G PQ P P+ P E ++ + P P P G E + P GP
Sbjct: 1055 LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1114
Query: 168 -----GPPAAPPPALDALSPFLR-KKAQILEVLRALEETDPLLLCSPATPWRPPG-QGP- 219
GP P PA A SP K +I E + + D P PPG QGP
Sbjct: 1115 RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK----GENGPPGPPGLQGPV 1170
Query: 220 GSPEPINGELCGPPQPEPS---------------PWAPCLLLGPGNLGGLLHWERLLGGL 264
G+P G+ G P P P P GP L GL G
Sbjct: 1171 GAPGIAGGD--GEPGPRGQQGMFGQKGDEGARGFPGPP----GPIGLQGLPGPPGEKGEN 1224
Query: 265 GGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSS-DEAGDPNEAPSPDTLLGALAR 323
G G P P PQ + GP PGS S E G+P EA +P
Sbjct: 1225 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP------P 1278
Query: 324 RQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGG 383
+ +G + +A GAAGP PG P P KG P
Sbjct: 1279 GEAGVGGPKGERGEKGEAGPPGAAGP-------PGAKGPPGDDGP-----KGNPGPVGFP 1326
Query: 384 GTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGE 443
G P A +G G GD PG P GPP P
Sbjct: 1327 GDPGPPGEPGPAGQDGVG-----------GDKGEDGDPGQP------------GPPGPSG 1363
Query: 444 AQGPLLPSPARGLKFLKLPPTSEKSPSPGGP-----QLSPQLPRNSRIPCRNSGSDGSPS 498
GP P RG PP + + G + + P P G G P
Sbjct: 1364 EAGPPGPPGKRG------PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1417
Query: 499 PLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYEN 558
P RG+ G P G QGLP A PGP+ P
Sbjct: 1418 PE-GLRGIPG----PVGEQGLP-------------------GAAGQDGPPGPMGPPGLPG 1453
Query: 559 ILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLP-ESYPYGS 617
+ S +G P L P Q P SPG +P + P G
Sbjct: 1454 LKGDPGS--KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1511
Query: 618 PQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPG 657
P L G + P + + G + +K G PG PG
Sbjct: 1512 PGPPGLP--GPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549
Score = 51.2 bits (121), Expect = 6e-06
Identities = 83/339 (24%), Positives = 106/339 (31%), Gaps = 78/339 (23%)
Query: 437 GPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGS 496
GPP P G + P +G P P GP P LP +P G
Sbjct: 454 GPPGPAGPAGIMGPPGLQG------PTGPPGDPGDRGPPGRPGLPGADGLP-------GP 500
Query: 497 PSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCY 556
P +L GG+ S + + LR P + T PGPV P
Sbjct: 501 PGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP-- 558
Query: 557 ENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYG 616
S +G S +P P Q P ++ P P P G
Sbjct: 559 ------GSSGAKGESGDPGP----------------QGPRGVQGP---PGPT-------G 586
Query: 617 SPQEKSLDKAGSESPHPGRRTPGNSSKKPSQG----------SGRR--------PGDPGS 658
P K G GR PG K +G G R PG PG
Sbjct: 587 KP-----GKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD 641
Query: 659 TPLRDRLAALGKL----KTGPEGALGSEKN-GVPARPGTEKTRG-PGKSGESA--GDMVP 710
+R +G + GP G LG G P +PG G PG G G+ P
Sbjct: 642 DGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP 701
Query: 711 SIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGA 749
+ + G +G + Q +PGL G PGA
Sbjct: 702 PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA 740
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 79.7 bits (195), Expect = 2e-14
Identities = 166/703 (23%), Positives = 223/703 (31%), Gaps = 160/703 (22%)
Query: 207 SPATPWRPPGQGPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGG 266
+P P +P G P G + PQ EP P PG G G
Sbjct: 620 TPGAPGQPGMAGVDGPPGPKGNM--GPQGEPGP--------PGQQGN-----------PG 658
Query: 267 EEDTGRPWGPSRGPPQAQGTSSGPNCA-----------PGSSSSSSSDEA-GDPNEA--- 311
+ P GP GPP +G P A PG S A G P
Sbjct: 659 PQGLPGPQGPI-GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI 717
Query: 312 --PSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQ 369
P P + GA R L G E E F G G L GD GQ + P+
Sbjct: 718 GYPGPRGVKGADGVRGLK-GSKGEKGEDGFPGF-KGDMG-LKGDRGEVGQIGPRGEDGPE 774
Query: 370 LSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSR--PGHPHSS 427
K + P G P A +G+ +P L + G P GS PG P ++
Sbjct: 775 GPKGRAGPTGDPG--------PSGQAGEKGKLGVPGLPGYPGR-QGPKGSTGFPGFPGAN 825
Query: 428 SQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIP 487
+ ++ G P P +GP P +RG + PT + P P P R P
Sbjct: 826 GEKGARGVAGKPGPRGQRGPTGPRGSRGAR----GPTGKPGPKGTSGGDGPPGPPGERGP 881
Query: 488 CRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLS 547
G G P P G P G GLP P T + PP
Sbjct: 882 QGPQGPVGFPGPK--------GPPGPPGKDGLPGHPGQRGETGFQGKTGPP--------G 925
Query: 548 PGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSP 607
PG VV P +GP+ E P + P PG P
Sbjct: 926 PGGVVGP-------------QGPTGETGPIGERGHPGP---------------PGPPGEQ 957
Query: 608 CLP----ESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRD 663
LP + G P + + +G + P R PG +QG+ PG G
Sbjct: 958 GLPGAAGKEGAKGDPGPQGI--SGKDGPAGLRGFPGERGLPGAQGA---PGLKG------ 1006
Query: 664 RLAALGKLKTGPEGALGSEKN----------GVPARPGTEKTRGPGKSGESAGDMVPSIH 713
G+ GP G +GS G+P RPG + GP + G+ P
Sbjct: 1007 -----GEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1061
Query: 714 RPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLT 773
+ ++ G+ G + + + G +G+PG + S G + + P P
Sbjct: 1062 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQK----GSKGDKGENGPPGPPGL-- 1115
Query: 774 KVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAP 833
+ P P A G+P + P P P
Sbjct: 1116 ------------------QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1157
Query: 834 LVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEG 876
+ + P P KG + G P PGP P QGP G
Sbjct: 1158 IGLQGLPGPPGEKG----ENGDVGPMGPPGPPGPRGP-QGPNG 1195
Score = 78.6 bits (192), Expect = 4e-14
Identities = 203/836 (24%), Positives = 268/836 (32%), Gaps = 125/836 (14%)
Query: 130 PASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDALSPFLRKKAQ 189
P P ++ +GP P P G+ Q E Q G PGP P P + P K Q
Sbjct: 624 PGQPGMAGVDGP--PGPKGNMGPQGEPGPPGQ--QGNPGPQGLPGPQ-GPIGPPGEKGPQ 678
Query: 190 ILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGE--LCGPPQPEPSPWAPCLLLG 247
L L D PPG PG E +GE GPP P+ P G
Sbjct: 679 GKPGLAGLPGADG-----------PPGH-PGK-EGQSGEKGALGPPGPQ----GPIGYPG 721
Query: 248 PGNLGGLLHWERLLGGLGGEEDTGRPWGPS-------RGP-----PQAQGTSSGPNCAPG 295
P + G L G G + + G P RG P+ + GP G
Sbjct: 722 PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 781
Query: 296 SSSSSS-SDEAGDPNEAPSPDTLLGALARRQLNLGQLL------EDTESYLQAFLAGAAG 348
+ S +AG+ + P L RQ G + E + +AG G
Sbjct: 782 PTGDPGPSGQAGEKGKLGVPG--LPGYPGRQGPKGSTGFPGFPGANGEKGARG-VAGKPG 838
Query: 349 PLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSM 408
P P + S + P K PK GG P PG QGP+ F
Sbjct: 839 PRGQRGPTGPRGSRGARGPT----GKPGPKGTSGGDGPPGP-PGERGPQGPQGPVGFPGP 893
Query: 409 FMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKS 468
G PGHP + + + GPP PG GP P+ G P E+
Sbjct: 894 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG-------PIGERG 946
Query: 469 -PSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCY 527
P P GP LP G+ G P P +G+ G + P G +G P
Sbjct: 947 HPGPPGPPGEQGLPG----AAGKEGAKGDPGP----QGISGKD-GPAGLRGFPGERG--- 994
Query: 528 TTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSR--STFRGPSPEPPPSPLQVPTYP 585
P + + PGPV SP + P P+ PP P P
Sbjct: 995 -LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053
Query: 586 -QLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKK 644
+ + P + ++ P P P + P GSP G + PG K
Sbjct: 1054 GEKGPQGPAGRDGVQGPVGLPGP----AGPAGSP--------GEDGDKGEIGEPGQKGSK 1101
Query: 645 PSQGSGRRPGDPG-STPLRDRLAALGKLKTGPEGALG-------SEKNGVPARPGTEKTR 696
+G PG PG P+ A G + GP G G G P PG +
Sbjct: 1102 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1161
Query: 697 G----PGKSGESAGDM-------VPSIHRPLEQLEAKG--GIRGAVALGTNSLKQQEPGL 743
G PG+ GE+ GD+ P P A G G G+V ++ EPG
Sbjct: 1162 GLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1220
Query: 744 MGDPG--ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSA 801
G+PG G R + P G P+ P P
Sbjct: 1221 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP--GAKGPPGDDGPKGNPGPVGFPGDP 1278
Query: 802 PSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWA---------- 851
G+P + + P P P P P +GPP A
Sbjct: 1279 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1338
Query: 852 -DCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPG 906
G A+ P GP P QGP G + E+ + GQ+ PG
Sbjct: 1339 GAKGEAGAEGPPGKTGPVGP-QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1393
Score = 72.0 bits (175), Expect = 4e-12
Identities = 194/790 (24%), Positives = 241/790 (30%), Gaps = 185/790 (23%)
Query: 208 PATPWRPPG-QGPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGG 266
PA PPG QGP P G+ GPP P A L PG G +L GG G
Sbjct: 410 PAGIMGPPGLQGPTGPPGDPGDR-GPPGRPGLPGADGL---PGPPGTMLMLPFRYGGDGS 465
Query: 267 EEDTGRPWGPS------------RGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNE---- 310
+ T RGPP G + P G SS + E+GDP
Sbjct: 466 KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPR 525
Query: 311 ----APSPDTLLGALARRQLNLGQ-------------------LLEDTESYLQAFLAGAA 347
P P G R + G+ L D + G
Sbjct: 526 GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 585
Query: 348 GP-----LNGDHPGPGQSSSPDQAPPQ-------LSKSKGLPKSAWGGGTP--------- 386
GP + G+ G P +A P+ + G P A G P
Sbjct: 586 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 645
Query: 387 -------EAHRPGFGATSEGQGPL-----------PFLSMFMGAGDAPLGSRPGHPHSSS 428
+ PG QGP+ P L+ GA D P PGHP
Sbjct: 646 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA-DGP----PGHPGKEG 700
Query: 429 QVKSKLQIGPPSPGEAQGPL-LPSP--------ARGLKFLKLPPTSEKSPSPGGP----- 474
Q K +GPP P QGP+ P P RGLK K + P G
Sbjct: 701 QSGEKGALGPPGP---QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 757
Query: 475 ------QLSPQLPRNSRIPCRNSGSDGSPSP--------LLARRGLGG--GELSPEGAQG 518
Q+ P+ P +G G P P L GL G G P+G+ G
Sbjct: 758 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 817
Query: 519 LPTSPSP--------CYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGP 570
P P P R P + + GP P + T G
Sbjct: 818 FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG-------PKGTSGGD 870
Query: 571 SPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSES 630
P PP + + PQ P P PP P + P
Sbjct: 871 GPPGPPG--------ERGPQGPQGPVGFPGPKGPPGPPGKDGLP---------------- 906
Query: 631 PHPGRR-TPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVPAR 689
HPG+R G K G G G G T + G GP G G + G+P
Sbjct: 907 GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG--HPGPPGPPGEQ--GLPGA 962
Query: 690 PGTEKTRG-PGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPG 748
G E +G PG G S D P+ R G +GA L Q PG +G PG
Sbjct: 963 AGKEGAKGDPGPQGISGKD-GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1021
Query: 749 ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVP--RTPAKVPTSAPSLGK 806
R S + L P P + G PQ P R + P P
Sbjct: 1022 ER--GSAGTAGPIGL-PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1078
Query: 807 PNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPG 866
P SP K + PG ++ K DKG+ P G P + G
Sbjct: 1079 PAGSPGEDGDK-------GEIGEPG-----QKGSKGDKGENGPPGPPGLQGPVGAPGIAG 1126
Query: 867 PTDPSQGPEG 876
D GP G
Sbjct: 1127 -GDGEPGPRG 1135
Score = 68.2 bits (165), Expect = 5e-11
Identities = 177/721 (24%), Positives = 225/721 (31%), Gaps = 180/721 (24%)
Query: 211 PWRPPG----QGPGSPEPINGELC--GPPQPEPSPWAPCLL--------LGPGNLGGLLH 256
P PPG QGP P G GPP + P P GP GG++
Sbjct: 872 PPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG 931
Query: 257 WERLLGGLGGEEDTGRPWGPSRGPPQAQGT-----SSGPNCAPGSSSSSSSDEAGDPNEA 311
+ G G + G P P GPP QG G PG S D
Sbjct: 932 PQGPTGETGPIGERGHPGPP--GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 989
Query: 312 PSPDTLLGALARRQLNLGQLLEDTESYL----QAFLAGAAGPLN-GDHPGPGQSSSPDQA 366
P L GA L G+ + + + AG AGP+ PGP Q
Sbjct: 990 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP-------QG 1042
Query: 367 PPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAG----DAPLGSRPG 422
PP + KG P G A R G QGP+ AG D G G
Sbjct: 1043 PPGPAGEKGAPGEK--GPQGPAGRDGV------QGPVGLPGPAGPAGSPGEDGDKGEI-G 1093
Query: 423 HPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPR 482
P K + GPP P QGP+ G P ++
Sbjct: 1094 EPGQKGSKGDKGENGPPGPPGLQGPV-----------------------GAPGIA----- 1125
Query: 483 NSRIPCRNSGSDGSPSPLLARRGLGG--GELSPEGAQGLPTSPSPCYTTPDSTQLRPPQS 540
G DG P P RG G G+ EGA+G P P P L P
Sbjct: 1126 ---------GGDGEPGP----RGQQGMFGQKGDEGARGFPGPPGPI----GLQGLPGPPG 1168
Query: 541 ALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSP--LQVPTYPQLTLEVPQAPEVL 598
GP+ P P P P P P P ++
Sbjct: 1169 EKGENGDVGPMGPP-------------GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215
Query: 599 RSPGVPPSPCLPESYPYGSPQEKSLDKA-----GSESPHPGRRTPGNSSKKPSQGSGRRP 653
PG +P P G P+ + +K G+ P + PG+ K + G P
Sbjct: 1216 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1275
Query: 654 GDPGSTPLRDRLAALGKLKTGPEG--ALGSEK--NGVPARPGTEKTRGPGKSGESAGDMV 709
GDPG + GP G +G +K +G P +PG PG SGE+
Sbjct: 1276 GDPGPPG-----------EPGPAGQDGVGGDKGEDGDPGQPGP-----PGPSGEAGPPGP 1319
Query: 710 PSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPR 769
P P A+G +Q E G G+ GA G PV P+
Sbjct: 1320 PGKRGPPGAAGAEG-------------RQGEKGAKGEAGAE-------GPPGKTGPVGPQ 1359
Query: 770 SCLTKV----------ELAKSRLAGALCPQVPRTPAKVPTSAPSLGKP-NKSPHSSPTKL 818
K + + L GA P P P G P +K P +
Sbjct: 1360 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1419
Query: 819 PSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDP--SQGPEG 876
P PG ++ K D+G GS A+ +PGP P GP G
Sbjct: 1420 GLIGP------PG-----EQGEKGDRGLP---GTQGSPGAKGDGGIPGPAGPLGPPGPPG 1465
Query: 877 L 877
L
Sbjct: 1466 L 1466
Score = 57.0 bits (136), Expect = 1e-07
Identities = 147/580 (25%), Positives = 180/580 (31%), Gaps = 117/580 (20%)
Query: 110 LTTGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGP-- 167
L G PQ P P+ P E ++ + P P P G E + P GP
Sbjct: 1004 LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1063
Query: 168 -----GPPAAPPPALDALSPFLR-KKAQILEVLRALEETDPLLLCSPATPWRPPG-QGP- 219
GP P PA A SP K +I E + + D P PPG QGP
Sbjct: 1064 RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK----GENGPPGPPGLQGPV 1119
Query: 220 GSPEPINGELCGPPQPEPS---------------PWAPCLLLGPGNLGGLLHWERLLGGL 264
G+P G+ G P P P P GP L GL G
Sbjct: 1120 GAPGIAGGD--GEPGPRGQQGMFGQKGDEGARGFPGPP----GPIGLQGLPGPPGEKGEN 1173
Query: 265 GGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSS-DEAGDPNEAPSPDTLLGALAR 323
G G P P PQ + GP PGS S E G+P EA +P
Sbjct: 1174 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP------P 1227
Query: 324 RQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGG 383
+ +G + +A GAAGP PG P P KG P
Sbjct: 1228 GEAGVGGPKGERGEKGEAGPPGAAGP-------PGAKGPPGDDGP-----KGNPGPVGFP 1275
Query: 384 GTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGE 443
G P A +G G GD PG P GPP P
Sbjct: 1276 GDPGPPGEPGPAGQDGVG-----------GDKGEDGDPGQP------------GPPGPSG 1312
Query: 444 AQGPLLPSPARGLKFLKLPPTSEKSPSPGGP-----QLSPQLPRNSRIPCRNSGSDGSPS 498
GP P RG PP + + G + + P P G G P
Sbjct: 1313 EAGPPGPPGKRG------PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1366
Query: 499 PLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYEN 558
P RG+ G P G QGLP A PGP+ P
Sbjct: 1367 PE-GLRGIPG----PVGEQGLP-------------------GAAGQDGPPGPMGPPGLPG 1402
Query: 559 ILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLP-ESYPYGS 617
+ S +G P L P Q P SPG +P + P G
Sbjct: 1403 LKGDPGS--KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1460
Query: 618 PQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPG 657
P L G + P + + G + +K G PG PG
Sbjct: 1461 PGPPGLP--GPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498
Score = 51.2 bits (121), Expect = 6e-06
Identities = 83/339 (24%), Positives = 106/339 (31%), Gaps = 78/339 (23%)
Query: 437 GPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGS 496
GPP P G + P +G P P GP P LP +P G
Sbjct: 403 GPPGPAGPAGIMGPPGLQG------PTGPPGDPGDRGPPGRPGLPGADGLP-------GP 449
Query: 497 PSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCY 556
P +L GG+ S + + LR P + T PGPV P
Sbjct: 450 PGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP-- 507
Query: 557 ENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYG 616
S +G S +P P Q P ++ P P P G
Sbjct: 508 ------GSSGAKGESGDPGP----------------QGPRGVQGP---PGPT-------G 535
Query: 617 SPQEKSLDKAGSESPHPGRRTPGNSSKKPSQG----------SGRR--------PGDPGS 658
P K G GR PG K +G G R PG PG
Sbjct: 536 KP-----GKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD 590
Query: 659 TPLRDRLAALGKL----KTGPEGALGSEKN-GVPARPGTEKTRG-PGKSGESA--GDMVP 710
+R +G + GP G LG G P +PG G PG G G+ P
Sbjct: 591 DGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP 650
Query: 711 SIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGA 749
+ + G +G + Q +PGL G PGA
Sbjct: 651 PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA 689
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 79.7 bits (195), Expect = 2e-14
Identities = 166/703 (23%), Positives = 223/703 (31%), Gaps = 160/703 (22%)
Query: 207 SPATPWRPPGQGPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGG 266
+P P +P G P G + PQ EP P PG G G
Sbjct: 659 TPGAPGQPGMAGVDGPPGPKGNM--GPQGEPGP--------PGQQGN-----------PG 697
Query: 267 EEDTGRPWGPSRGPPQAQGTSSGPNCA-----------PGSSSSSSSDEA-GDPNEA--- 311
+ P GP GPP +G P A PG S A G P
Sbjct: 698 PQGLPGPQGPI-GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI 756
Query: 312 --PSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQ 369
P P + GA R L G E E F G G L GD GQ + P+
Sbjct: 757 GYPGPRGVKGADGVRGLK-GSKGEKGEDGFPGF-KGDMG-LKGDRGEVGQIGPRGEDGPE 813
Query: 370 LSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSR--PGHPHSS 427
K + P G P A +G+ +P L + G P GS PG P ++
Sbjct: 814 GPKGRAGPTGDPG--------PSGQAGEKGKLGVPGLPGYPGR-QGPKGSTGFPGFPGAN 864
Query: 428 SQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIP 487
+ ++ G P P +GP P +RG + PT + P P P R P
Sbjct: 865 GEKGARGVAGKPGPRGQRGPTGPRGSRGAR----GPTGKPGPKGTSGGDGPPGPPGERGP 920
Query: 488 CRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLS 547
G G P P G P G GLP P T + PP
Sbjct: 921 QGPQGPVGFPGPK--------GPPGPPGKDGLPGHPGQRGETGFQGKTGPP--------G 964
Query: 548 PGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSP 607
PG VV P +GP+ E P + P PG P
Sbjct: 965 PGGVVGP-------------QGPTGETGPIGERGHPGP---------------PGPPGEQ 996
Query: 608 CLP----ESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRD 663
LP + G P + + +G + P R PG +QG+ PG G
Sbjct: 997 GLPGAAGKEGAKGDPGPQGI--SGKDGPAGLRGFPGERGLPGAQGA---PGLKG------ 1045
Query: 664 RLAALGKLKTGPEGALGSEKN----------GVPARPGTEKTRGPGKSGESAGDMVPSIH 713
G+ GP G +GS G+P RPG + GP + G+ P
Sbjct: 1046 -----GEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1100
Query: 714 RPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLT 773
+ ++ G+ G + + + G +G+PG + S G + + P P
Sbjct: 1101 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQK----GSKGDKGENGPPGPPGL-- 1154
Query: 774 KVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAP 833
+ P P A G+P + P P P
Sbjct: 1155 ------------------QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1196
Query: 834 LVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEG 876
+ + P P KG + G P PGP P QGP G
Sbjct: 1197 IGLQGLPGPPGEKG----ENGDVGPMGPPGPPGPRGP-QGPNG 1234
Score = 78.6 bits (192), Expect = 4e-14
Identities = 203/836 (24%), Positives = 268/836 (32%), Gaps = 125/836 (14%)
Query: 130 PASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDALSPFLRKKAQ 189
P P ++ +GP P P G+ Q E Q G PGP P P + P K Q
Sbjct: 663 PGQPGMAGVDGP--PGPKGNMGPQGEPGPPGQ--QGNPGPQGLPGPQ-GPIGPPGEKGPQ 717
Query: 190 ILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGE--LCGPPQPEPSPWAPCLLLG 247
L L D PPG PG E +GE GPP P+ P G
Sbjct: 718 GKPGLAGLPGADG-----------PPGH-PGK-EGQSGEKGALGPPGPQ----GPIGYPG 760
Query: 248 PGNLGGLLHWERLLGGLGGEEDTGRPWGPS-------RGP-----PQAQGTSSGPNCAPG 295
P + G L G G + + G P RG P+ + GP G
Sbjct: 761 PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 820
Query: 296 SSSSSS-SDEAGDPNEAPSPDTLLGALARRQLNLGQLL------EDTESYLQAFLAGAAG 348
+ S +AG+ + P L RQ G + E + +AG G
Sbjct: 821 PTGDPGPSGQAGEKGKLGVPG--LPGYPGRQGPKGSTGFPGFPGANGEKGARG-VAGKPG 877
Query: 349 PLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSM 408
P P + S + P K PK GG P PG QGP+ F
Sbjct: 878 PRGQRGPTGPRGSRGARGPT----GKPGPKGTSGGDGPPGP-PGERGPQGPQGPVGFPGP 932
Query: 409 FMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKS 468
G PGHP + + + GPP PG GP P+ G P E+
Sbjct: 933 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG-------PIGERG 985
Query: 469 -PSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCY 527
P P GP LP G+ G P P +G+ G + P G +G P
Sbjct: 986 HPGPPGPPGEQGLPG----AAGKEGAKGDPGP----QGISGKD-GPAGLRGFPGERG--- 1033
Query: 528 TTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSR--STFRGPSPEPPPSPLQVPTYP 585
P + + PGPV SP + P P+ PP P P
Sbjct: 1034 -LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1092
Query: 586 -QLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKK 644
+ + P + ++ P P P + P GSP G + PG K
Sbjct: 1093 GEKGPQGPAGRDGVQGPVGLPGP----AGPAGSP--------GEDGDKGEIGEPGQKGSK 1140
Query: 645 PSQGSGRRPGDPG-STPLRDRLAALGKLKTGPEGALG-------SEKNGVPARPGTEKTR 696
+G PG PG P+ A G + GP G G G P PG +
Sbjct: 1141 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1200
Query: 697 G----PGKSGESAGDM-------VPSIHRPLEQLEAKG--GIRGAVALGTNSLKQQEPGL 743
G PG+ GE+ GD+ P P A G G G+V ++ EPG
Sbjct: 1201 GLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1259
Query: 744 MGDPG--ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSA 801
G+PG G R + P G P+ P P
Sbjct: 1260 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP--GAKGPPGDDGPKGNPGPVGFPGDP 1317
Query: 802 PSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWA---------- 851
G+P + + P P P P P +GPP A
Sbjct: 1318 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1377
Query: 852 -DCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPG 906
G A+ P GP P QGP G + E+ + GQ+ PG
Sbjct: 1378 GAKGEAGAEGPPGKTGPVGP-QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1432
Score = 72.0 bits (175), Expect = 4e-12
Identities = 194/790 (24%), Positives = 241/790 (30%), Gaps = 185/790 (23%)
Query: 208 PATPWRPPG-QGPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGG 266
PA PPG QGP P G+ GPP P A L PG G +L GG G
Sbjct: 449 PAGIMGPPGLQGPTGPPGDPGDR-GPPGRPGLPGADGL---PGPPGTMLMLPFRYGGDGS 504
Query: 267 EEDTGRPWGPS------------RGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNE---- 310
+ T RGPP G + P G SS + E+GDP
Sbjct: 505 KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPR 564
Query: 311 ----APSPDTLLGALARRQLNLGQ-------------------LLEDTESYLQAFLAGAA 347
P P G R + G+ L D + G
Sbjct: 565 GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 624
Query: 348 GP-----LNGDHPGPGQSSSPDQAPPQ-------LSKSKGLPKSAWGGGTP--------- 386
GP + G+ G P +A P+ + G P A G P
Sbjct: 625 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 684
Query: 387 -------EAHRPGFGATSEGQGPL-----------PFLSMFMGAGDAPLGSRPGHPHSSS 428
+ PG QGP+ P L+ GA D P PGHP
Sbjct: 685 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA-DGP----PGHPGKEG 739
Query: 429 QVKSKLQIGPPSPGEAQGPL-LPSP--------ARGLKFLKLPPTSEKSPSPGGP----- 474
Q K +GPP P QGP+ P P RGLK K + P G
Sbjct: 740 QSGEKGALGPPGP---QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 796
Query: 475 ------QLSPQLPRNSRIPCRNSGSDGSPSP--------LLARRGLGG--GELSPEGAQG 518
Q+ P+ P +G G P P L GL G G P+G+ G
Sbjct: 797 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 856
Query: 519 LPTSPSP--------CYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGP 570
P P P R P + + GP P + T G
Sbjct: 857 FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG-------PKGTSGGD 909
Query: 571 SPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSES 630
P PP + + PQ P P PP P + P
Sbjct: 910 GPPGPPG--------ERGPQGPQGPVGFPGPKGPPGPPGKDGLP---------------- 945
Query: 631 PHPGRR-TPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVPAR 689
HPG+R G K G G G G T + G GP G G + G+P
Sbjct: 946 GHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG--HPGPPGPPGEQ--GLPGA 1001
Query: 690 PGTEKTRG-PGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPG 748
G E +G PG G S D P+ R G +GA L Q PG +G PG
Sbjct: 1002 AGKEGAKGDPGPQGISGKD-GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1060
Query: 749 ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVP--RTPAKVPTSAPSLGK 806
R S + L P P + G PQ P R + P P
Sbjct: 1061 ER--GSAGTAGPIGL-PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1117
Query: 807 PNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPG 866
P SP K + PG ++ K DKG+ P G P + G
Sbjct: 1118 PAGSPGEDGDK-------GEIGEPG-----QKGSKGDKGENGPPGPPGLQGPVGAPGIAG 1165
Query: 867 PTDPSQGPEG 876
D GP G
Sbjct: 1166 -GDGEPGPRG 1174
Score = 68.2 bits (165), Expect = 5e-11
Identities = 177/721 (24%), Positives = 225/721 (31%), Gaps = 180/721 (24%)
Query: 211 PWRPPG----QGPGSPEPINGELC--GPPQPEPSPWAPCLL--------LGPGNLGGLLH 256
P PPG QGP P G GPP + P P GP GG++
Sbjct: 911 PPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG 970
Query: 257 WERLLGGLGGEEDTGRPWGPSRGPPQAQGT-----SSGPNCAPGSSSSSSSDEAGDPNEA 311
+ G G + G P P GPP QG G PG S D
Sbjct: 971 PQGPTGETGPIGERGHPGPP--GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 1028
Query: 312 PSPDTLLGALARRQLNLGQLLEDTESYL----QAFLAGAAGPLN-GDHPGPGQSSSPDQA 366
P L GA L G+ + + + AG AGP+ PGP Q
Sbjct: 1029 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP-------QG 1081
Query: 367 PPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAG----DAPLGSRPG 422
PP + KG P G A R G QGP+ AG D G G
Sbjct: 1082 PPGPAGEKGAPGEK--GPQGPAGRDGV------QGPVGLPGPAGPAGSPGEDGDKGEI-G 1132
Query: 423 HPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPR 482
P K + GPP P QGP+ G P ++
Sbjct: 1133 EPGQKGSKGDKGENGPPGPPGLQGPV-----------------------GAPGIA----- 1164
Query: 483 NSRIPCRNSGSDGSPSPLLARRGLGG--GELSPEGAQGLPTSPSPCYTTPDSTQLRPPQS 540
G DG P P RG G G+ EGA+G P P P L P
Sbjct: 1165 ---------GGDGEPGP----RGQQGMFGQKGDEGARGFPGPPGPI----GLQGLPGPPG 1207
Query: 541 ALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSP--LQVPTYPQLTLEVPQAPEVL 598
GP+ P P P P P P P ++
Sbjct: 1208 EKGENGDVGPMGPP-------------GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254
Query: 599 RSPGVPPSPCLPESYPYGSPQEKSLDKA-----GSESPHPGRRTPGNSSKKPSQGSGRRP 653
PG +P P G P+ + +K G+ P + PG+ K + G P
Sbjct: 1255 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1314
Query: 654 GDPGSTPLRDRLAALGKLKTGPEG--ALGSEK--NGVPARPGTEKTRGPGKSGESAGDMV 709
GDPG + GP G +G +K +G P +PG PG SGE+
Sbjct: 1315 GDPGPPG-----------EPGPAGQDGVGGDKGEDGDPGQPGP-----PGPSGEAGPPGP 1358
Query: 710 PSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPR 769
P P A+G +Q E G G+ GA G PV P+
Sbjct: 1359 PGKRGPPGAAGAEG-------------RQGEKGAKGEAGAE-------GPPGKTGPVGPQ 1398
Query: 770 SCLTKV----------ELAKSRLAGALCPQVPRTPAKVPTSAPSLGKP-NKSPHSSPTKL 818
K + + L GA P P P G P +K P +
Sbjct: 1399 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1458
Query: 819 PSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDP--SQGPEG 876
P PG ++ K D+G GS A+ +PGP P GP G
Sbjct: 1459 GLIGP------PG-----EQGEKGDRGLP---GTQGSPGAKGDGGIPGPAGPLGPPGPPG 1504
Query: 877 L 877
L
Sbjct: 1505 L 1505
Score = 57.0 bits (136), Expect = 1e-07
Identities = 147/580 (25%), Positives = 180/580 (31%), Gaps = 117/580 (20%)
Query: 110 LTTGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGP-- 167
L G PQ P P+ P E ++ + P P P G E + P GP
Sbjct: 1043 LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1102
Query: 168 -----GPPAAPPPALDALSPFLR-KKAQILEVLRALEETDPLLLCSPATPWRPPG-QGP- 219
GP P PA A SP K +I E + + D P PPG QGP
Sbjct: 1103 RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK----GENGPPGPPGLQGPV 1158
Query: 220 GSPEPINGELCGPPQPEPS---------------PWAPCLLLGPGNLGGLLHWERLLGGL 264
G+P G+ G P P P P GP L GL G
Sbjct: 1159 GAPGIAGGD--GEPGPRGQQGMFGQKGDEGARGFPGPP----GPIGLQGLPGPPGEKGEN 1212
Query: 265 GGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSS-DEAGDPNEAPSPDTLLGALAR 323
G G P P PQ + GP PGS S E G+P EA +P
Sbjct: 1213 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP------P 1266
Query: 324 RQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGG 383
+ +G + +A GAAGP PG P P KG P
Sbjct: 1267 GEAGVGGPKGERGEKGEAGPPGAAGP-------PGAKGPPGDDGP-----KGNPGPVGFP 1314
Query: 384 GTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGE 443
G P A +G G GD PG P GPP P
Sbjct: 1315 GDPGPPGEPGPAGQDGVG-----------GDKGEDGDPGQP------------GPPGPSG 1351
Query: 444 AQGPLLPSPARGLKFLKLPPTSEKSPSPGGP-----QLSPQLPRNSRIPCRNSGSDGSPS 498
GP P RG PP + + G + + P P G G P
Sbjct: 1352 EAGPPGPPGKRG------PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1405
Query: 499 PLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYEN 558
P RG+ G P G QGLP A PGP+ P
Sbjct: 1406 PE-GLRGIPG----PVGEQGLP-------------------GAAGQDGPPGPMGPPGLPG 1441
Query: 559 ILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLP-ESYPYGS 617
+ S +G P L P Q P SPG +P + P G
Sbjct: 1442 LKGDPGS--KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1499
Query: 618 PQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPG 657
P L G + P + + G + +K G PG PG
Sbjct: 1500 PGPPGLP--GPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537
Score = 51.2 bits (121), Expect = 6e-06
Identities = 83/339 (24%), Positives = 106/339 (31%), Gaps = 78/339 (23%)
Query: 437 GPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGS 496
GPP P G + P +G P P GP P LP +P G
Sbjct: 442 GPPGPAGPAGIMGPPGLQG------PTGPPGDPGDRGPPGRPGLPGADGLP-------GP 488
Query: 497 PSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCY 556
P +L GG+ S + + LR P + T PGPV P
Sbjct: 489 PGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP-- 546
Query: 557 ENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYG 616
S +G S +P P Q P ++ P P P G
Sbjct: 547 ------GSSGAKGESGDPGP----------------QGPRGVQGP---PGPT-------G 574
Query: 617 SPQEKSLDKAGSESPHPGRRTPGNSSKKPSQG----------SGRR--------PGDPGS 658
P K G GR PG K +G G R PG PG
Sbjct: 575 KP-----GKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD 629
Query: 659 TPLRDRLAALGKL----KTGPEGALGSEKN-GVPARPGTEKTRG-PGKSGESA--GDMVP 710
+R +G + GP G LG G P +PG G PG G G+ P
Sbjct: 630 DGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP 689
Query: 711 SIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGA 749
+ + G +G + Q +PGL G PGA
Sbjct: 690 PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA 728
>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
sapiens]
Length = 1424
Score = 78.2 bits (191), Expect = 5e-14
Identities = 318/1338 (23%), Positives = 425/1338 (31%), Gaps = 258/1338 (19%)
Query: 112 TGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPA 171
TGS ++ L S P P GP + + C+G + +Q PG PG
Sbjct: 87 TGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG----EQGFPGLPGTLG 142
Query: 172 APP-PALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQG----PGSPEPIN 226
P P L +K A E E+ + P P P QG PG P P+
Sbjct: 143 YPGIPGAAGLKG--QKGAPAKE-----EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPV- 194
Query: 227 GELCGPPQPE-----PSPWAPCLLLGP-GNLGGLLHWERLLGGLGGEEDTGRPWGPSRGP 280
GPP P P P GP G++G ER++G G G GP P
Sbjct: 195 ----GPPGPPGFFGFPGAMGP---RGPKGHMG-----ERVIGHKGERGVKGLT-GPPGPP 241
Query: 281 PQAQGTSSGP-NCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYL 339
T +GP N G+P P P L G ESY
Sbjct: 242 GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP-PGPSGLPG----------------ESY- 283
Query: 340 QAFLAGAAGPLNGDHPG----PGQSSSPDQAPPQLSK-SKGLP----KSAWGGGTPEAHR 390
G+ GD PG PG+ P + K ++G P + G +
Sbjct: 284 -----GSEKGAPGD-PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337
Query: 391 PGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPP----SPGEAQG 446
PGF +GP + + GD PG P + GPP SPG ++
Sbjct: 338 PGF------RGPTEYYDTYQEKGDE---GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP 388
Query: 447 PLLPSPA----RGLKFLKLPPTSEKSPSPGGPQL--SPQLPRNSRIPCRNSGSDGSPSPL 500
L +P +G K + P + +PG P SP LP + G G P +
Sbjct: 389 GLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP-------GPPGPPGDI 441
Query: 501 LARRGLGGGELSPEGAQGLPTS-PSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENI 559
+ R+G P G GLP SP D + P PGP P +
Sbjct: 442 VFRKG-------PPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGL 494
Query: 560 LDLS----RSTFRGPSPEP-PPSPLQVPTYPQ---------LTLEVPQAPEVLRSPGVPP 605
+ R G P P +P +P L E + + GVP
Sbjct: 495 HGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG 554
Query: 606 SPCLPESYPYGSPQEKSLDKAGSESPHPGRRTP-GNSSKKPSQGSGRRPGDPGSTPLRDR 664
P L G P K LD G P G + +G PGDPGS
Sbjct: 555 DPGLR-----GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGP 609
Query: 665 LAALGKLKTGPEGALGSEKN----GVPARPGTEKTRG--------------PGKSGESAG 706
G GP+G G + G P PG RG PG G
Sbjct: 610 AGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669
Query: 707 DMVPSIHRPLEQLEAKG--------GIRGAVALGTNSLKQQE-----------PGLMGDP 747
P I L + G GI G G K + PG MG+P
Sbjct: 670 QGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729
Query: 748 G--ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGAL----CPQVPRTPAKVPTSA 801
G + + G P P + E S G + P +P TP
Sbjct: 730 GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDG 789
Query: 802 P--SLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVT-------KESPKPDKGKGPPWAD 852
P G+P P + P PG + K PK D G P
Sbjct: 790 PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI-PGLDR 848
Query: 853 CGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAEVKHR 912
G +P +PG GP G + + E+ V+ + G A G
Sbjct: 849 SGFPGETGSPGIPGHQG-EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907
Query: 913 NTSSIASWFGLKKSK-LPALN--RRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNIS 969
N + G + S +P + R T K ++G G+P E+ L
Sbjct: 908 NPGTP----GQRGSPGIPGVKGQRGTPGAKGEQG-DKGNPGPSEISHVIGDKGEPGLK-G 961
Query: 970 KLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPNTGLGQVQGQLAGMYQGADTFMQQL 1029
E R + + P P GP PGP LG +G M +
Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP-PGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020
Query: 1030 -LNRVDGKE----LPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPP 1084
+ GK P ++ R P Q D P + G R G PP
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ---GDKGEPGYSEGTRPG----------PP 1067
Query: 1085 GKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFP--PPDHGSSGTPS- 1141
G P+ +PG +M + + +P P H G G P P HG G
Sbjct: 1068 G-PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 1142 KNLPKTKPPRLDPPPGVP--PARPPPL--------TKVP-----------RRAHTLEREV 1180
K L PP + PPG+P P P P+ +P RA R
Sbjct: 1127 KGL--LGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN 1184
Query: 1181 PGIEELLVSGRHPSMPAFP----ALLPAAP-GHRGHETCPDDPCEDPGPTPPVQLAKNWT 1235
PG + P P P A+ A P G G E P P PG P Q N
Sbjct: 1185 PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPP-GLPGAIIPGQTG-NRG 1242
Query: 1236 FPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPS 1295
P +R + + P P + G+ + + S P P+GPP +
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGI------------KGDKGSMGHPGPKGPP------GT 1284
Query: 1296 TSDMAEEGRVASGGPPGL 1313
DM GR+ + G PGL
Sbjct: 1285 AGDMGPPGRLGAPGTPGL 1302
Score = 67.0 bits (162), Expect = 1e-10
Identities = 210/829 (25%), Positives = 263/829 (31%), Gaps = 200/829 (24%)
Query: 121 TPLQPPSEPPASPSLSSTEG-PAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAP------ 173
TP+ P PP P +G P P LG C PG PGP P
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD-----------PGLPGPDGEPGIPGIG 700
Query: 174 ---PPALDALSPFLRKKAQI--------------LEVLRALEETDPLLLCSPATPWRPPG 216
PP F K + + A E + P TP P
Sbjct: 701 FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760
Query: 217 QG----------------PGSP--EPINGELCGPPQPEP----SPWAPCLLLGPGNLGGL 254
+G PG+P E ++G P QP P P C + GP GL
Sbjct: 761 RGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC-IEGPRGAQGL 819
Query: 255 LHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSP 314
L GL G++ GP P PG S E G P P
Sbjct: 820 PG----LNGLKGQQGRRGKTGPKGDPG-----------IPGLDRSGFPGETGSPG-IPGH 863
Query: 315 DTLLGALARRQLN-----LGQLLEDTESYLQAFLAGAAGPLNGDHPG-PGQSSSPDQAPP 368
+G L +R LG ED + F GA GP PG PG +P Q
Sbjct: 864 QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF-PGAIGP-----PGPPGNPGTPGQ--- 914
Query: 369 QLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSS 428
S G+P GTP A G GP + G+ L G+P
Sbjct: 915 --RGSPGIPGVKGQRGTPGA--KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK- 969
Query: 429 QVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLS---PQLPRNSR 485
G P +P GLK LK P P P G S P P
Sbjct: 970 -------------GNRGVPGMP----GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012
Query: 486 IPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTT 545
IP + G+ G P R G L G G P P D + P S +
Sbjct: 1013 IP-GSMGNMGMPGSKGKR-----GTLGFPGRAGRPGLPGIHGLQGDKGE--PGYSEGTRP 1064
Query: 546 LSPGPVVSPCYENILDLSRSTFRGPSPEP-PPSPLQVPTYPQLTLEVPQAPEVLRSPGVP 604
PGP P D+ + +G +P PP L P PE +PG P
Sbjct: 1065 GPPGPTGDPGLPG--DMGK---KGEMGQPGPPGHLG-----------PAGPE--GAPGSP 1106
Query: 605 PSPCLP-ESYPYGSPQEKS----LDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGST 659
SP LP + P+G K L G P PG+ +G R G PG
Sbjct: 1107 GSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPA 1166
Query: 660 PLRDRLAALGKLKTGPEGALGSE----KNGVPARPGTEKTRGPGKSGESAGDMVPSIHRP 715
+ L + GP G G++ G P PG PG+ G + GD P
Sbjct: 1167 GEKGETGLL-RAPPGPRGNPGAQGAKGDRGAPGFPGL-----PGRKG-AMGDAGPRGPTG 1219
Query: 716 LEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGA----RVYSSHSMGARVDLEPVSPRSC 771
+E G+ GA+ G + PG G PGA SH +G + D
Sbjct: 1220 IEGFPGPPGLPGAIIPGQTG-NRGPPGSRGSPGAPGPPGPPGSHVIGIKGD--------- 1269
Query: 772 LTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPG 831
G++ P+ P P +A +G P + LP P G
Sbjct: 1270 -----------KGSMGHPGPKGP---PGTAGDMGPPGRLGAPGTPGLP--GPRGDPGFQG 1313
Query: 832 APLVTKES-----------PKPDKGKGPPW--ADCGSTTAQSTPLVPGP 867
P V E P P KGPP D G+ S P PGP
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP 1362
Score = 47.4 bits (111), Expect = 9e-05
Identities = 111/418 (26%), Positives = 138/418 (33%), Gaps = 96/418 (22%)
Query: 141 PAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDALSPFLRKKAQILEVLRALEET 200
P P G + E + + RPG PGP P L + KK + + +
Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDP-----GLPGDMGKKGE-------MGQP 1088
Query: 201 DPLLLCSPATPWRPPGQG-----PGSPEP--------INGELCGPPQPEPSPWAPCLLLG 247
P PA P PG PG P P I G L GPP P P
Sbjct: 1089 GPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG-LLGPPGIRGPPGLPGFPGS 1147
Query: 248 PGNLG--GLLHWERLLGGLGGEEDTG---RPWGPSRGPPQAQGTSSGPNCAPG----SSS 298
PG +G G + + G G + +TG P GP RG P AQG + G APG
Sbjct: 1148 PGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP-RGNPGAQG-AKGDRGAPGFPGLPGR 1205
Query: 299 SSSSDEAGDPNEA-----PSPDTLLGALARRQL-NLGQLLEDTESYLQAFLAGAAGP--- 349
+ +AG P P L GA+ Q N G S G GP
Sbjct: 1206 KGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGP----PGSRGSPGAPGPPGPPGS 1261
Query: 350 ----LNGD-----HPGPG--QSSSPDQAPPQLSKSKGLPKSAWGGGTP----------EA 388
+ GD HPGP ++ D PP + G P G P E
Sbjct: 1262 HVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEK 1321
Query: 389 HRPGFGATSEGQGPLPFLSMFMGAGDA------PLGSRPGHPHSSSQVKSKLQIGPPSPG 442
PGF + GP+ GD L PG P + + + + GPP P
Sbjct: 1322 GNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381
Query: 443 EAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPL 500
GP P G K PG P P + N GS G P L
Sbjct: 1382 GNLGPCGPRGKPG-----------KDGKPGTPG-----PAGEK---GNKGSKGEPESL 1420
>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
sapiens]
Length = 1494
Score = 78.2 bits (191), Expect = 5e-14
Identities = 318/1338 (23%), Positives = 425/1338 (31%), Gaps = 258/1338 (19%)
Query: 112 TGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPA 171
TGS ++ L S P P GP + + C+G + +Q PG PG
Sbjct: 87 TGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG----EQGFPGLPGTLG 142
Query: 172 APP-PALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQG----PGSPEPIN 226
P P L +K A E E+ + P P P QG PG P P+
Sbjct: 143 YPGIPGAAGLKG--QKGAPAKE-----EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPV- 194
Query: 227 GELCGPPQPE-----PSPWAPCLLLGP-GNLGGLLHWERLLGGLGGEEDTGRPWGPSRGP 280
GPP P P P GP G++G ER++G G G GP P
Sbjct: 195 ----GPPGPPGFFGFPGAMGP---RGPKGHMG-----ERVIGHKGERGVKGLT-GPPGPP 241
Query: 281 PQAQGTSSGP-NCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYL 339
T +GP N G+P P P L G ESY
Sbjct: 242 GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP-PGPSGLPG----------------ESY- 283
Query: 340 QAFLAGAAGPLNGDHPG----PGQSSSPDQAPPQLSK-SKGLP----KSAWGGGTPEAHR 390
G+ GD PG PG+ P + K ++G P + G +
Sbjct: 284 -----GSEKGAPGD-PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337
Query: 391 PGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPP----SPGEAQG 446
PGF +GP + + GD PG P + GPP SPG ++
Sbjct: 338 PGF------RGPTEYYDTYQEKGDE---GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP 388
Query: 447 PLLPSPA----RGLKFLKLPPTSEKSPSPGGPQL--SPQLPRNSRIPCRNSGSDGSPSPL 500
L +P +G K + P + +PG P SP LP + G G P +
Sbjct: 389 GLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP-------GPPGPPGDI 441
Query: 501 LARRGLGGGELSPEGAQGLPTS-PSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENI 559
+ R+G P G GLP SP D + P PGP P +
Sbjct: 442 VFRKG-------PPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGL 494
Query: 560 LDLS----RSTFRGPSPEP-PPSPLQVPTYPQ---------LTLEVPQAPEVLRSPGVPP 605
+ R G P P +P +P L E + + GVP
Sbjct: 495 HGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG 554
Query: 606 SPCLPESYPYGSPQEKSLDKAGSESPHPGRRTP-GNSSKKPSQGSGRRPGDPGSTPLRDR 664
P L G P K LD G P G + +G PGDPGS
Sbjct: 555 DPGLR-----GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGP 609
Query: 665 LAALGKLKTGPEGALGSEKN----GVPARPGTEKTRG--------------PGKSGESAG 706
G GP+G G + G P PG RG PG G
Sbjct: 610 AGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669
Query: 707 DMVPSIHRPLEQLEAKG--------GIRGAVALGTNSLKQQE-----------PGLMGDP 747
P I L + G GI G G K + PG MG+P
Sbjct: 670 QGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729
Query: 748 G--ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGAL----CPQVPRTPAKVPTSA 801
G + + G P P + E S G + P +P TP
Sbjct: 730 GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDG 789
Query: 802 P--SLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVT-------KESPKPDKGKGPPWAD 852
P G+P P + P PG + K PK D G P
Sbjct: 790 PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI-PGLDR 848
Query: 853 CGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAEVKHR 912
G +P +PG GP G + + E+ V+ + G A G
Sbjct: 849 SGFPGETGSPGIPGHQG-EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907
Query: 913 NTSSIASWFGLKKSK-LPALN--RRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNIS 969
N + G + S +P + R T K ++G G+P E+ L
Sbjct: 908 NPGTP----GQRGSPGIPGVKGQRGTPGAKGEQG-DKGNPGPSEISHVIGDKGEPGLK-G 961
Query: 970 KLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPNTGLGQVQGQLAGMYQGADTFMQQL 1029
E R + + P P GP PGP LG +G M +
Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP-PGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020
Query: 1030 -LNRVDGKE----LPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPP 1084
+ GK P ++ R P Q D P + G R G PP
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ---GDKGEPGYSEGTRPG----------PP 1067
Query: 1085 GKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFP--PPDHGSSGTPS- 1141
G P+ +PG +M + + +P P H G G P P HG G
Sbjct: 1068 G-PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 1142 KNLPKTKPPRLDPPPGVP--PARPPPL--------TKVP-----------RRAHTLEREV 1180
K L PP + PPG+P P P P+ +P RA R
Sbjct: 1127 KGL--LGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN 1184
Query: 1181 PGIEELLVSGRHPSMPAFP----ALLPAAP-GHRGHETCPDDPCEDPGPTPPVQLAKNWT 1235
PG + P P P A+ A P G G E P P PG P Q N
Sbjct: 1185 PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPP-GLPGAIIPGQTG-NRG 1242
Query: 1236 FPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPS 1295
P +R + + P P + G+ + + S P P+GPP +
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGI------------KGDKGSMGHPGPKGPP------GT 1284
Query: 1296 TSDMAEEGRVASGGPPGL 1313
DM GR+ + G PGL
Sbjct: 1285 AGDMGPPGRLGAPGTPGL 1302
Score = 67.0 bits (162), Expect = 1e-10
Identities = 210/829 (25%), Positives = 263/829 (31%), Gaps = 200/829 (24%)
Query: 121 TPLQPPSEPPASPSLSSTEG-PAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAP------ 173
TP+ P PP P +G P P LG C PG PGP P
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD-----------PGLPGPDGEPGIPGIG 700
Query: 174 ---PPALDALSPFLRKKAQI--------------LEVLRALEETDPLLLCSPATPWRPPG 216
PP F K + + A E + P TP P
Sbjct: 701 FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760
Query: 217 QG----------------PGSP--EPINGELCGPPQPEP----SPWAPCLLLGPGNLGGL 254
+G PG+P E ++G P QP P P C + GP GL
Sbjct: 761 RGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC-IEGPRGAQGL 819
Query: 255 LHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSP 314
L GL G++ GP P PG S E G P P
Sbjct: 820 PG----LNGLKGQQGRRGKTGPKGDPG-----------IPGLDRSGFPGETGSPG-IPGH 863
Query: 315 DTLLGALARRQLN-----LGQLLEDTESYLQAFLAGAAGPLNGDHPG-PGQSSSPDQAPP 368
+G L +R LG ED + F GA GP PG PG +P Q
Sbjct: 864 QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF-PGAIGP-----PGPPGNPGTPGQ--- 914
Query: 369 QLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSS 428
S G+P GTP A G GP + G+ L G+P
Sbjct: 915 --RGSPGIPGVKGQRGTPGA--KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK- 969
Query: 429 QVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLS---PQLPRNSR 485
G P +P GLK LK P P P G S P P
Sbjct: 970 -------------GNRGVPGMP----GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012
Query: 486 IPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTT 545
IP + G+ G P R G L G G P P D + P S +
Sbjct: 1013 IP-GSMGNMGMPGSKGKR-----GTLGFPGRAGRPGLPGIHGLQGDKGE--PGYSEGTRP 1064
Query: 546 LSPGPVVSPCYENILDLSRSTFRGPSPEP-PPSPLQVPTYPQLTLEVPQAPEVLRSPGVP 604
PGP P D+ + +G +P PP L P PE +PG P
Sbjct: 1065 GPPGPTGDPGLPG--DMGK---KGEMGQPGPPGHLG-----------PAGPE--GAPGSP 1106
Query: 605 PSPCLP-ESYPYGSPQEKS----LDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGST 659
SP LP + P+G K L G P PG+ +G R G PG
Sbjct: 1107 GSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPA 1166
Query: 660 PLRDRLAALGKLKTGPEGALGSE----KNGVPARPGTEKTRGPGKSGESAGDMVPSIHRP 715
+ L + GP G G++ G P PG PG+ G + GD P
Sbjct: 1167 GEKGETGLL-RAPPGPRGNPGAQGAKGDRGAPGFPGL-----PGRKG-AMGDAGPRGPTG 1219
Query: 716 LEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGA----RVYSSHSMGARVDLEPVSPRSC 771
+E G+ GA+ G + PG G PGA SH +G + D
Sbjct: 1220 IEGFPGPPGLPGAIIPGQTG-NRGPPGSRGSPGAPGPPGPPGSHVIGIKGD--------- 1269
Query: 772 LTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPG 831
G++ P+ P P +A +G P + LP P G
Sbjct: 1270 -----------KGSMGHPGPKGP---PGTAGDMGPPGRLGAPGTPGLP--GPRGDPGFQG 1313
Query: 832 APLVTKES-----------PKPDKGKGPPW--ADCGSTTAQSTPLVPGP 867
P V E P P KGPP D G+ S P PGP
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP 1362
Score = 36.2 bits (82), Expect = 0.22
Identities = 65/274 (23%), Positives = 83/274 (30%), Gaps = 31/274 (11%)
Query: 1070 RNGLVGPLQGCGK------PPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLD 1123
R+G+ GP G+ PPG P PG + + P A G
Sbjct: 1159 RDGIPGPAGEKGETGLLRAPPG-PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP 1217
Query: 1124 SGIGTFPPPDHGSSGTPSKNLP----KTKPPRLDPPPGVPPARPPPLTKV-------PRR 1172
+GI FP P G P +P PP PG P PP + V
Sbjct: 1218 TGIEGFPGPP----GLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSM 1273
Query: 1173 AHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCEDPGPTPPVQLAK 1232
H + PG + P P L P G G + P E P +
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGL-PGPRGDPGFQGFPGVKGEKGNPGFLGSIGP 1332
Query: 1233 NWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPT-------PQG 1285
G DP L G P P P + EP P P P+G
Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPP-GTPGEPGMQGEPGPPGPPGNLGPCGPRG 1391
Query: 1286 PPFGGSRTPSTSDMAEEGRVASGGPPGLETSESL 1319
P + + E+G S G PG S+ L
Sbjct: 1392 KPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL 1425
>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
sapiens]
Length = 1637
Score = 78.2 bits (191), Expect = 5e-14
Identities = 318/1338 (23%), Positives = 425/1338 (31%), Gaps = 258/1338 (19%)
Query: 112 TGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPA 171
TGS ++ L S P P GP + + C+G + +Q PG PG
Sbjct: 87 TGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG----EQGFPGLPGTLG 142
Query: 172 APP-PALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQG----PGSPEPIN 226
P P L +K A E E+ + P P P QG PG P P+
Sbjct: 143 YPGIPGAAGLKG--QKGAPAKE-----EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPV- 194
Query: 227 GELCGPPQPE-----PSPWAPCLLLGP-GNLGGLLHWERLLGGLGGEEDTGRPWGPSRGP 280
GPP P P P GP G++G ER++G G G GP P
Sbjct: 195 ----GPPGPPGFFGFPGAMGP---RGPKGHMG-----ERVIGHKGERGVKGLT-GPPGPP 241
Query: 281 PQAQGTSSGP-NCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYL 339
T +GP N G+P P P L G ESY
Sbjct: 242 GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP-PGPSGLPG----------------ESY- 283
Query: 340 QAFLAGAAGPLNGDHPG----PGQSSSPDQAPPQLSK-SKGLP----KSAWGGGTPEAHR 390
G+ GD PG PG+ P + K ++G P + G +
Sbjct: 284 -----GSEKGAPGD-PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337
Query: 391 PGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPP----SPGEAQG 446
PGF +GP + + GD PG P + GPP SPG ++
Sbjct: 338 PGF------RGPTEYYDTYQEKGDE---GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP 388
Query: 447 PLLPSPA----RGLKFLKLPPTSEKSPSPGGPQL--SPQLPRNSRIPCRNSGSDGSPSPL 500
L +P +G K + P + +PG P SP LP + G G P +
Sbjct: 389 GLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP-------GPPGPPGDI 441
Query: 501 LARRGLGGGELSPEGAQGLPTS-PSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENI 559
+ R+G P G GLP SP D + P PGP P +
Sbjct: 442 VFRKG-------PPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGL 494
Query: 560 LDLS----RSTFRGPSPEP-PPSPLQVPTYPQ---------LTLEVPQAPEVLRSPGVPP 605
+ R G P P +P +P L E + + GVP
Sbjct: 495 HGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG 554
Query: 606 SPCLPESYPYGSPQEKSLDKAGSESPHPGRRTP-GNSSKKPSQGSGRRPGDPGSTPLRDR 664
P L G P K LD G P G + +G PGDPGS
Sbjct: 555 DPGLR-----GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGP 609
Query: 665 LAALGKLKTGPEGALGSEKN----GVPARPGTEKTRG--------------PGKSGESAG 706
G GP+G G + G P PG RG PG G
Sbjct: 610 AGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669
Query: 707 DMVPSIHRPLEQLEAKG--------GIRGAVALGTNSLKQQE-----------PGLMGDP 747
P I L + G GI G G K + PG MG+P
Sbjct: 670 QGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729
Query: 748 G--ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGAL----CPQVPRTPAKVPTSA 801
G + + G P P + E S G + P +P TP
Sbjct: 730 GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDG 789
Query: 802 P--SLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVT-------KESPKPDKGKGPPWAD 852
P G+P P + P PG + K PK D G P
Sbjct: 790 PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI-PGLDR 848
Query: 853 CGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAEVKHR 912
G +P +PG GP G + + E+ V+ + G A G
Sbjct: 849 SGFPGETGSPGIPGHQG-EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907
Query: 913 NTSSIASWFGLKKSK-LPALN--RRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNIS 969
N + G + S +P + R T K ++G G+P E+ L
Sbjct: 908 NPGTP----GQRGSPGIPGVKGQRGTPGAKGEQG-DKGNPGPSEISHVIGDKGEPGLK-G 961
Query: 970 KLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPNTGLGQVQGQLAGMYQGADTFMQQL 1029
E R + + P P GP PGP LG +G M +
Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP-PGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020
Query: 1030 -LNRVDGKE----LPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPP 1084
+ GK P ++ R P Q D P + G R G PP
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ---GDKGEPGYSEGTRPG----------PP 1067
Query: 1085 GKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFP--PPDHGSSGTPS- 1141
G P+ +PG +M + + +P P H G G P P HG G
Sbjct: 1068 G-PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 1142 KNLPKTKPPRLDPPPGVP--PARPPPL--------TKVP-----------RRAHTLEREV 1180
K L PP + PPG+P P P P+ +P RA R
Sbjct: 1127 KGL--LGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN 1184
Query: 1181 PGIEELLVSGRHPSMPAFP----ALLPAAP-GHRGHETCPDDPCEDPGPTPPVQLAKNWT 1235
PG + P P P A+ A P G G E P P PG P Q N
Sbjct: 1185 PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPP-GLPGAIIPGQTG-NRG 1242
Query: 1236 FPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPS 1295
P +R + + P P + G+ + + S P P+GPP +
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGI------------KGDKGSMGHPGPKGPP------GT 1284
Query: 1296 TSDMAEEGRVASGGPPGL 1313
DM GR+ + G PGL
Sbjct: 1285 AGDMGPPGRLGAPGTPGL 1302
Score = 67.0 bits (162), Expect = 1e-10
Identities = 210/829 (25%), Positives = 263/829 (31%), Gaps = 200/829 (24%)
Query: 121 TPLQPPSEPPASPSLSSTEG-PAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAP------ 173
TP+ P PP P +G P P LG C PG PGP P
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD-----------PGLPGPDGEPGIPGIG 700
Query: 174 ---PPALDALSPFLRKKAQI--------------LEVLRALEETDPLLLCSPATPWRPPG 216
PP F K + + A E + P TP P
Sbjct: 701 FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760
Query: 217 QG----------------PGSP--EPINGELCGPPQPEP----SPWAPCLLLGPGNLGGL 254
+G PG+P E ++G P QP P P C + GP GL
Sbjct: 761 RGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC-IEGPRGAQGL 819
Query: 255 LHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSP 314
L GL G++ GP P PG S E G P P
Sbjct: 820 PG----LNGLKGQQGRRGKTGPKGDPG-----------IPGLDRSGFPGETGSPG-IPGH 863
Query: 315 DTLLGALARRQLN-----LGQLLEDTESYLQAFLAGAAGPLNGDHPG-PGQSSSPDQAPP 368
+G L +R LG ED + F GA GP PG PG +P Q
Sbjct: 864 QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF-PGAIGP-----PGPPGNPGTPGQ--- 914
Query: 369 QLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSS 428
S G+P GTP A G GP + G+ L G+P
Sbjct: 915 --RGSPGIPGVKGQRGTPGA--KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK- 969
Query: 429 QVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLS---PQLPRNSR 485
G P +P GLK LK P P P G S P P
Sbjct: 970 -------------GNRGVPGMP----GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012
Query: 486 IPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTT 545
IP + G+ G P R G L G G P P D + P S +
Sbjct: 1013 IP-GSMGNMGMPGSKGKR-----GTLGFPGRAGRPGLPGIHGLQGDKGE--PGYSEGTRP 1064
Query: 546 LSPGPVVSPCYENILDLSRSTFRGPSPEP-PPSPLQVPTYPQLTLEVPQAPEVLRSPGVP 604
PGP P D+ + +G +P PP L P PE +PG P
Sbjct: 1065 GPPGPTGDPGLPG--DMGK---KGEMGQPGPPGHLG-----------PAGPE--GAPGSP 1106
Query: 605 PSPCLP-ESYPYGSPQEKS----LDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGST 659
SP LP + P+G K L G P PG+ +G R G PG
Sbjct: 1107 GSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPA 1166
Query: 660 PLRDRLAALGKLKTGPEGALGSE----KNGVPARPGTEKTRGPGKSGESAGDMVPSIHRP 715
+ L + GP G G++ G P PG PG+ G + GD P
Sbjct: 1167 GEKGETGLL-RAPPGPRGNPGAQGAKGDRGAPGFPGL-----PGRKG-AMGDAGPRGPTG 1219
Query: 716 LEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGA----RVYSSHSMGARVDLEPVSPRSC 771
+E G+ GA+ G + PG G PGA SH +G + D
Sbjct: 1220 IEGFPGPPGLPGAIIPGQTG-NRGPPGSRGSPGAPGPPGPPGSHVIGIKGD--------- 1269
Query: 772 LTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPG 831
G++ P+ P P +A +G P + LP P G
Sbjct: 1270 -----------KGSMGHPGPKGP---PGTAGDMGPPGRLGAPGTPGLP--GPRGDPGFQG 1313
Query: 832 APLVTKES-----------PKPDKGKGPPW--ADCGSTTAQSTPLVPGP 867
P V E P P KGPP D G+ S P PGP
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP 1362
Score = 36.2 bits (82), Expect = 0.22
Identities = 65/274 (23%), Positives = 83/274 (30%), Gaps = 31/274 (11%)
Query: 1070 RNGLVGPLQGCGK------PPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLD 1123
R+G+ GP G+ PPG P PG + + P A G
Sbjct: 1159 RDGIPGPAGEKGETGLLRAPPG-PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP 1217
Query: 1124 SGIGTFPPPDHGSSGTPSKNLP----KTKPPRLDPPPGVPPARPPPLTKV-------PRR 1172
+GI FP P G P +P PP PG P PP + V
Sbjct: 1218 TGIEGFPGPP----GLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSM 1273
Query: 1173 AHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCEDPGPTPPVQLAK 1232
H + PG + P P L P G G + P E P +
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGL-PGPRGDPGFQGFPGVKGEKGNPGFLGSIGP 1332
Query: 1233 NWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPT-------PQG 1285
G DP L G P P P + EP P P P+G
Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPP-GTPGEPGMQGEPGPPGPPGNLGPCGPRG 1391
Query: 1286 PPFGGSRTPSTSDMAEEGRVASGGPPGLETSESL 1319
P + + E+G S G PG S+ L
Sbjct: 1392 KPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL 1425
>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
sapiens]
Length = 1670
Score = 78.2 bits (191), Expect = 5e-14
Identities = 318/1338 (23%), Positives = 425/1338 (31%), Gaps = 258/1338 (19%)
Query: 112 TGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPA 171
TGS ++ L S P P GP + + C+G + +Q PG PG
Sbjct: 87 TGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG----EQGFPGLPGTLG 142
Query: 172 APP-PALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQG----PGSPEPIN 226
P P L +K A E E+ + P P P QG PG P P+
Sbjct: 143 YPGIPGAAGLKG--QKGAPAKE-----EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPV- 194
Query: 227 GELCGPPQPE-----PSPWAPCLLLGP-GNLGGLLHWERLLGGLGGEEDTGRPWGPSRGP 280
GPP P P P GP G++G ER++G G G GP P
Sbjct: 195 ----GPPGPPGFFGFPGAMGP---RGPKGHMG-----ERVIGHKGERGVKGLT-GPPGPP 241
Query: 281 PQAQGTSSGP-NCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYL 339
T +GP N G+P P P L G ESY
Sbjct: 242 GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP-PGPSGLPG----------------ESY- 283
Query: 340 QAFLAGAAGPLNGDHPG----PGQSSSPDQAPPQLSK-SKGLP----KSAWGGGTPEAHR 390
G+ GD PG PG+ P + K ++G P + G +
Sbjct: 284 -----GSEKGAPGD-PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337
Query: 391 PGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPP----SPGEAQG 446
PGF +GP + + GD PG P + GPP SPG ++
Sbjct: 338 PGF------RGPTEYYDTYQEKGDE---GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRP 388
Query: 447 PLLPSPA----RGLKFLKLPPTSEKSPSPGGPQL--SPQLPRNSRIPCRNSGSDGSPSPL 500
L +P +G K + P + +PG P SP LP + G G P +
Sbjct: 389 GLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP-------GPPGPPGDI 441
Query: 501 LARRGLGGGELSPEGAQGLPTS-PSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENI 559
+ R+G P G GLP SP D + P PGP P +
Sbjct: 442 VFRKG-------PPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGL 494
Query: 560 LDLS----RSTFRGPSPEP-PPSPLQVPTYPQ---------LTLEVPQAPEVLRSPGVPP 605
+ R G P P +P +P L E + + GVP
Sbjct: 495 HGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG 554
Query: 606 SPCLPESYPYGSPQEKSLDKAGSESPHPGRRTP-GNSSKKPSQGSGRRPGDPGSTPLRDR 664
P L G P K LD G P G + +G PGDPGS
Sbjct: 555 DPGLR-----GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGP 609
Query: 665 LAALGKLKTGPEGALGSEKN----GVPARPGTEKTRG--------------PGKSGESAG 706
G GP+G G + G P PG RG PG G
Sbjct: 610 AGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669
Query: 707 DMVPSIHRPLEQLEAKG--------GIRGAVALGTNSLKQQE-----------PGLMGDP 747
P I L + G GI G G K + PG MG+P
Sbjct: 670 QGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729
Query: 748 G--ARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGAL----CPQVPRTPAKVPTSA 801
G + + G P P + E S G + P +P TP
Sbjct: 730 GLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDG 789
Query: 802 P--SLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVT-------KESPKPDKGKGPPWAD 852
P G+P P + P PG + K PK D G P
Sbjct: 790 PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI-PGLDR 848
Query: 853 CGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAEVKHR 912
G +P +PG GP G + + E+ V+ + G A G
Sbjct: 849 SGFPGETGSPGIPGHQG-EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907
Query: 913 NTSSIASWFGLKKSK-LPALN--RRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNIS 969
N + G + S +P + R T K ++G G+P E+ L
Sbjct: 908 NPGTP----GQRGSPGIPGVKGQRGTPGAKGEQG-DKGNPGPSEISHVIGDKGEPGLK-G 961
Query: 970 KLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPNTGLGQVQGQLAGMYQGADTFMQQL 1029
E R + + P P GP PGP LG +G M +
Sbjct: 962 FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP-PGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020
Query: 1030 -LNRVDGKE----LPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPP 1084
+ GK P ++ R P Q D P + G R G PP
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ---GDKGEPGYSEGTRPG----------PP 1067
Query: 1085 GKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFP--PPDHGSSGTPS- 1141
G P+ +PG +M + + +P P H G G P P HG G
Sbjct: 1068 G-PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 1142 KNLPKTKPPRLDPPPGVP--PARPPPL--------TKVP-----------RRAHTLEREV 1180
K L PP + PPG+P P P P+ +P RA R
Sbjct: 1127 KGL--LGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN 1184
Query: 1181 PGIEELLVSGRHPSMPAFP----ALLPAAP-GHRGHETCPDDPCEDPGPTPPVQLAKNWT 1235
PG + P P P A+ A P G G E P P PG P Q N
Sbjct: 1185 PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPP-GLPGAIIPGQTG-NRG 1242
Query: 1236 FPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPS 1295
P +R + + P P + G+ + + S P P+GPP +
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGI------------KGDKGSMGHPGPKGPP------GT 1284
Query: 1296 TSDMAEEGRVASGGPPGL 1313
DM GR+ + G PGL
Sbjct: 1285 AGDMGPPGRLGAPGTPGL 1302
Score = 67.0 bits (162), Expect = 1e-10
Identities = 210/829 (25%), Positives = 263/829 (31%), Gaps = 200/829 (24%)
Query: 121 TPLQPPSEPPASPSLSSTEG-PAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAP------ 173
TP+ P PP P +G P P LG C PG PGP P
Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD-----------PGLPGPDGEPGIPGIG 700
Query: 174 ---PPALDALSPFLRKKAQI--------------LEVLRALEETDPLLLCSPATPWRPPG 216
PP F K + + A E + P TP P
Sbjct: 701 FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760
Query: 217 QG----------------PGSP--EPINGELCGPPQPEP----SPWAPCLLLGPGNLGGL 254
+G PG+P E ++G P QP P P C + GP GL
Sbjct: 761 RGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC-IEGPRGAQGL 819
Query: 255 LHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSP 314
L GL G++ GP P PG S E G P P
Sbjct: 820 PG----LNGLKGQQGRRGKTGPKGDPG-----------IPGLDRSGFPGETGSPG-IPGH 863
Query: 315 DTLLGALARRQLN-----LGQLLEDTESYLQAFLAGAAGPLNGDHPG-PGQSSSPDQAPP 368
+G L +R LG ED + F GA GP PG PG +P Q
Sbjct: 864 QGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF-PGAIGP-----PGPPGNPGTPGQ--- 914
Query: 369 QLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSS 428
S G+P GTP A G GP + G+ L G+P
Sbjct: 915 --RGSPGIPGVKGQRGTPGA--KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK- 969
Query: 429 QVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLS---PQLPRNSR 485
G P +P GLK LK P P P G S P P
Sbjct: 970 -------------GNRGVPGMP----GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012
Query: 486 IPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTT 545
IP + G+ G P R G L G G P P D + P S +
Sbjct: 1013 IP-GSMGNMGMPGSKGKR-----GTLGFPGRAGRPGLPGIHGLQGDKGE--PGYSEGTRP 1064
Query: 546 LSPGPVVSPCYENILDLSRSTFRGPSPEP-PPSPLQVPTYPQLTLEVPQAPEVLRSPGVP 604
PGP P D+ + +G +P PP L P PE +PG P
Sbjct: 1065 GPPGPTGDPGLPG--DMGK---KGEMGQPGPPGHLG-----------PAGPE--GAPGSP 1106
Query: 605 PSPCLP-ESYPYGSPQEKS----LDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGST 659
SP LP + P+G K L G P PG+ +G R G PG
Sbjct: 1107 GSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPA 1166
Query: 660 PLRDRLAALGKLKTGPEGALGSE----KNGVPARPGTEKTRGPGKSGESAGDMVPSIHRP 715
+ L + GP G G++ G P PG PG+ G + GD P
Sbjct: 1167 GEKGETGLL-RAPPGPRGNPGAQGAKGDRGAPGFPGL-----PGRKG-AMGDAGPRGPTG 1219
Query: 716 LEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGA----RVYSSHSMGARVDLEPVSPRSC 771
+E G+ GA+ G + PG G PGA SH +G + D
Sbjct: 1220 IEGFPGPPGLPGAIIPGQTG-NRGPPGSRGSPGAPGPPGPPGSHVIGIKGD--------- 1269
Query: 772 LTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPG 831
G++ P+ P P +A +G P + LP P G
Sbjct: 1270 -----------KGSMGHPGPKGP---PGTAGDMGPPGRLGAPGTPGLP--GPRGDPGFQG 1313
Query: 832 APLVTKES-----------PKPDKGKGPPW--ADCGSTTAQSTPLVPGP 867
P V E P P KGPP D G+ S P PGP
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP 1362
Score = 36.2 bits (82), Expect = 0.22
Identities = 65/274 (23%), Positives = 83/274 (30%), Gaps = 31/274 (11%)
Query: 1070 RNGLVGPLQGCGK------PPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLD 1123
R+G+ GP G+ PPG P PG + + P A G
Sbjct: 1159 RDGIPGPAGEKGETGLLRAPPG-PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP 1217
Query: 1124 SGIGTFPPPDHGSSGTPSKNLP----KTKPPRLDPPPGVPPARPPPLTKV-------PRR 1172
+GI FP P G P +P PP PG P PP + V
Sbjct: 1218 TGIEGFPGPP----GLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSM 1273
Query: 1173 AHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCEDPGPTPPVQLAK 1232
H + PG + P P L P G G + P E P +
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGL-PGPRGDPGFQGFPGVKGEKGNPGFLGSIGP 1332
Query: 1233 NWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPT-------PQG 1285
G DP L G P P P + EP P P P+G
Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPP-GTPGEPGMQGEPGPPGPPGNLGPCGPRG 1391
Query: 1286 PPFGGSRTPSTSDMAEEGRVASGGPPGLETSESL 1319
P + + E+G S G PG S+ L
Sbjct: 1392 KPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL 1425
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 77.4 bits (189), Expect = 8e-14
Identities = 218/850 (25%), Positives = 264/850 (31%), Gaps = 181/850 (21%)
Query: 115 LPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPP 174
LP P + P PP P +G P P G + + PG PG P P
Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGP-PGISIPGPPGLDGQ----PGAPGLPGPPG 438
Query: 175 PALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPG-------QGPGSPEPING 227
PA + P +D +C P P PPG QG + G
Sbjct: 439 PAGPHIPP-----------------SDE--ICEPGPP-GPPGSPGDKGLQGEQGVKGDKG 478
Query: 228 ELC------GPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPP 281
+ C G P P P L PG+LG G GE+ GP +G P
Sbjct: 479 DTCFNCIGTGISGPPGQPGLPGLPGPPGSLG--------FPGQKGEKGQAGATGP-KGLP 529
Query: 282 QAQGTSSGPNCAPGSSS-----------SSSSDEAGDPNEAPSPDTLLGALARRQLNLGQ 330
G P PGS E G P AP L G + L G
Sbjct: 530 GIPGAPGAPG-FPGSKGEPGDILTFPGMKGDKGELGSPG-APGLPGLPGTPGQDGLP-GL 586
Query: 331 LLEDTESYLQAFLAGAAGPLNGDHPG----PGQSSSPDQAPPQLSKSKGLPKSAWGGGTP 386
E F P N PG G P PP KG+ A G P
Sbjct: 587 PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQP 646
Query: 387 ----EAHRPGFGATSEGQGPLPFLSMFMG----AGDAPLGSRPGHPHSSSQVKSKLQIGP 438
PG T G+ LP G GD L +PG P SK + G
Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG---SKGEPGI 703
Query: 439 PSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPG-----GPQLSPQLPRNSRIPCRNSGS 493
P G LP P F +P +PG GP P P P
Sbjct: 704 PGIG------LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP--GFAL 755
Query: 494 DGSPSPLLARRGLGG--GELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPV 551
G P P GL G G L P+G +G P P P T L P+ + PGP+
Sbjct: 756 PGPPGP----PGLPGFKGALGPKGDRGFPGPPGPPGRT-GLDGLPGPKGDVGPNGQPGPM 810
Query: 552 VSPCYENILDLSRSTFRGPSPEPP--PSPLQVPTYPQLT----------LEVPQAPEVLR 599
P I +GP P PP P P+ P + L+VP P
Sbjct: 811 GPPGLPGI------GVQGP-PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863
Query: 600 SPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGST 659
SPG+P +P P G P L S PG K G PG PG
Sbjct: 864 SPGIPGAP-----GPIGPPGSPGLPGKAGASGFPG--------TKGEMGMMGPPGPPGPL 910
Query: 660 PLRDRLAALGKLK-----------TGPEGALGSE-KNGVPARPGTEKTRGPGKSGESAGD 707
+ R G LK GP G GS+ + G+P PG G GE
Sbjct: 911 GIPGRSGVPG-LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969
Query: 708 MVPSI--------HRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGA 759
+P I ++ L + G+ G L + PGL G PG
Sbjct: 970 GLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL---------- 1019
Query: 760 RVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNK-----SPHSS 814
+ P K + G + P P+ VP S G P + P S
Sbjct: 1020 ------IGPPG--LKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS 1071
Query: 815 PTKLPSKSPTKVVP----RPGAPLVTKESPKPDKG--KGPPWADCGSTTAQSTPLVPGPT 868
LP K P PG P + P G P A G P PGP
Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK-GQPGLPGFPGTPGPP 1130
Query: 869 DPS--QGPEG 876
P GP G
Sbjct: 1131 GPKGISGPPG 1140
Score = 75.9 bits (185), Expect = 2e-13
Identities = 199/818 (24%), Positives = 264/818 (32%), Gaps = 162/818 (19%)
Query: 125 PPSEP-----PASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDA 179
PP P P P + +G P + C G + ++ PG PG P P
Sbjct: 94 PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKG----ERGFPGSPGFPGLQGPPGPP 149
Query: 180 LSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPPQPEP-- 237
P ++ + + ++ +L P +P P P QG P I G + GPP P
Sbjct: 150 GIPGMKGEPGSI-IMSSL----PGPKGNPGYPGPPGIQGLPGPTGIPGPI-GPPGPPGLM 203
Query: 238 SPWAPCLLLGP-GNLGGLLHWERLLGGLGGEEDTGRPWGPS------------------- 277
P P L GP GN+G L+++ G G + G P P
Sbjct: 204 GPPGPPGLPGPKGNMG--LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261
Query: 278 ----RGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLE 333
RGPP G P P E G+P + P +
Sbjct: 262 LPGDRGPPGPPGIRGPPG--PPGGEKGEKGEQGEPGKRGKPG-----------------K 302
Query: 334 DTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGF 393
D E+ Q + G G PG P + + K P G P RPG
Sbjct: 303 DGENG-QPGIPGLPGD-------PGYPGEPGRDGEKGQKGDTGPPGPPGLVIP---RPGT 351
Query: 394 GAT--SEGQGPLPFLSMFMGAGDAP-LGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLP 450
G T +G LP L G P + PG P +GPP P G
Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAV----MGPPGPPGFPGERGQ 407
Query: 451 SPARGLKFLKLPPTSEKSPSPGGPQL-SPQLPRNSRIPCRNS-------GSDGSPSP--L 500
G + +P PG P L P P IP + G GSP L
Sbjct: 408 KGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL 467
Query: 501 LARRG------------LGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSP 548
+G +G G P G GLP P P P S + +
Sbjct: 468 QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGP----PGSLGFPGQKGEKGQAGAT 523
Query: 549 GPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPC 608
GP P F G EP + T+P + + + L SPG P P
Sbjct: 524 GPKGLPGIPGAP--GAPGFPGSKGEPG----DILTFPGMKGDKGE----LGSPGAPGLPG 573
Query: 609 LPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAAL 668
LP G+P + L G P + PG + K +G PG+PG L + +
Sbjct: 574 LP-----GTPGQDGLP--GLPGP---KGEPGGITFKGERGP---PGNPGLPGLPGNIGPM 620
Query: 669 GKLKTGPEGALGSEK-NGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQ-LEAKGGIR 726
G GP G +G + GV PG GP GD +I +P + L G
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGP------KGDPGQTITQPGKPGLPGNPGRD 674
Query: 727 GAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGAL 786
G V L + +PGL G PG++ EP P L K
Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKG------------EPGIPGIGLPGPPGPKGFPGIPG 722
Query: 787 CPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAP-----LVTKESPK 841
P P TP ++ P P P P P +P P P PK
Sbjct: 723 PPGAPGTPGRIGLEGPP------GPPGFPG--PKGEPGFALPGPPGPPGLPGFKGALGPK 774
Query: 842 PDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAP 879
D+G P G T P G P+ P + P
Sbjct: 775 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812
Score = 72.8 bits (177), Expect = 2e-12
Identities = 210/827 (25%), Positives = 271/827 (32%), Gaps = 163/827 (19%)
Query: 116 PQIPLTPLQPPSEPPASPSLSSTEG----------PAAP-LPLGHCAGQREVCWEQQLRP 164
P +P +Q P PP P G P P L + G+R
Sbjct: 813 PGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER---------- 862
Query: 165 GGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQG--PG-- 220
G PG P AP P SP L KA E + P P PG+ PG
Sbjct: 863 GSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLK 922
Query: 221 SPEPINGE--LCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPS- 277
+ + G+ L GP + S P L PG + LLG G + + G P P
Sbjct: 923 GDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD-----PNLLGSKGEKGEPGLPGIPGV 977
Query: 278 RGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLN--LGQLLEDT 335
GP QG P PG S P P G + L +G +
Sbjct: 978 SGPKGYQGLPGDPG-QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM---- 1032
Query: 336 ESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGA 395
G GP + P PG S P Q S GLP G P G
Sbjct: 1033 ---------GFPGPQGVEGP-PGPSGVPGQPG-----SPGLPGQKGDKGDP-------GI 1070
Query: 396 TSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIG-PPSPGEAQGPLLPSPAR 454
+S G LP G+ L PG+P V G P +PG P LP
Sbjct: 1071 SSIGLPGLPGPK-----GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF-- 1123
Query: 455 GLKFLKLPPTSEKSPSP---GGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGG--G 509
P + P P GP +P LP P G G P P +G G G
Sbjct: 1124 --------PGTPGPPGPKGISGPPGNPGLPGEPG-PVGGGGHPGQPGPP-GEKGKPGQDG 1173
Query: 510 ELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRG 569
P G +G P P + P L PG +P F G
Sbjct: 1174 IPGPAGQKGEPGQPG--FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG--PKGEPGFHG 1229
Query: 570 -PSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGS 628
P + PP P P P LE P+ + P P P + P G
Sbjct: 1230 FPGVQGPPGP---PGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLP------------GP 1274
Query: 629 ESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVPA 688
E P PG PGN K +G+ +PG PG L K GP G G+ P
Sbjct: 1275 EGP-PG--LPGNGGIKGEKGNPGQPGLPGLPGL--------KGDQGPPGLQGN-----PG 1318
Query: 689 RPGTEKTRG-PGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDP 747
RPG +G PG G VP G++G + ++ + EPGL+G P
Sbjct: 1319 RPGLNGMKGDPGLPG------VPGF----------PGMKGPSGVPGSAGPEGEPGLIGPP 1362
Query: 748 GARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKP 807
G S + + P + L L G PQ P P G P
Sbjct: 1363 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGL--KGLPGPQGPQGLPGPTGPPGDPGRNGLP 1420
Query: 808 ---NKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLV 864
LP + T+ + P P PD +GPP S+ A +
Sbjct: 1421 GFDGAGGRKGDPGLPGQPGTRGLDGP---------PGPDGLQGPPGPPGTSSVAHGFLIT 1471
Query: 865 --PGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAEV 909
TD Q P+G +V +G ++L +QG +RA G ++
Sbjct: 1472 RHSQTTDAPQCPQGTL-------QVYEGF--SLLYVQGNKRAHGQDL 1509
Score = 56.2 bits (134), Expect = 2e-07
Identities = 182/713 (25%), Positives = 226/713 (31%), Gaps = 162/713 (22%)
Query: 208 PATPWRPPGQGPGSPEPINGE--LCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLG 265
P P P +GP P G+ + GPP P+ P L PG G L G+
Sbjct: 59 PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPG--------LPGMP 110
Query: 266 GEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQ 325
G + G P GP +G P GT G PGS P P
Sbjct: 111 GHD--GAP-GP-QGIPGCNGTK-GERGFPGSPGFPGLQGPPGPPGIPG------------ 153
Query: 326 LNLGQLLEDTESYLQAFLAGAAGPLNGDHPGP-GQSSSPDQAPPQLSKSKGLPKSAWGGG 384
+ + S + + L G G N +PGP G P P + G P G
Sbjct: 154 -----MKGEPGSIIMSSLPGPKG--NPGYPGPPGIQGLP--GPTGIPGPIGPPGPPGLMG 204
Query: 385 TPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQI-------- 436
P PG G L F G+ L PG P S+ K + +
Sbjct: 205 PPGP--PGLPGPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261
Query: 437 -----GPPSPGEAQGPLLPSPARGLKFLK----------LPPTSEKSPSPGGPQLSPQLP 481
GPP P +GP P P G K K P ++ PG P L P P
Sbjct: 262 LPGDRGPPGPPGIRGP--PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL-PGDP 318
Query: 482 RNSRIPCRN--------SGSDGSPSPLLARRGLGG--GELSPEGAQGLPTSPS----PCY 527
P R+ +G G P ++ R G G GE G GLP P
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI 378
Query: 528 TTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQL 587
P PP +A+ PGP P RG + P + +P P L
Sbjct: 379 QGPPGLP-GPPGAAVMGP--PGPPGFPGE-----------RGQKGDEGPPGISIPGPPGL 424
Query: 588 TLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQ 647
+ P AP + PG P P +P S E PG P
Sbjct: 425 DGQ-PGAPGLPGPPG-PAGPHIPPS---------------DEICEPGPPGP--------- 458
Query: 648 GSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGD 707
PG PG L+ G +G+ +G P +PG GP S G
Sbjct: 459 -----PGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513
Query: 708 MVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVS 767
KG A A G L PG+ G PGA + S G D+
Sbjct: 514 --------------KGEKGQAGATGPKGL----PGIPGAPGAPGFPG-SKGEPGDI-LTF 553
Query: 768 PRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVV 827
P K EL G P +P TP + P L P P + K
Sbjct: 554 PGMKGDKGELGSPGAPG--LPGLPGTPGQ--DGLPGL----PGPKGEPGGITFKGERGPP 605
Query: 828 PRPGAP-LVTKESPKPDKGKGPPWADCGSTTAQST------PLVPGPT-DPSQ 872
PG P L P G GPP G Q P +PGP DP Q
Sbjct: 606 GNPGLPGLPGNIGPMGPPGFGPP-GPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657
Score = 53.1 bits (126), Expect = 2e-06
Identities = 123/464 (26%), Positives = 160/464 (34%), Gaps = 112/464 (24%)
Query: 437 GPPSP-GEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDG 495
GPP P G+ +P P G K ++ PP P G P L P +P G DG
Sbjct: 69 GPPGPRGQKGDDGIPGPP-GPKGIRGPPGLPGFP--GTPGL-PGMP----------GHDG 114
Query: 496 SPSPLLARRGLGGGELSPEGAQGLPTSPS-PCYTTPDSTQLRP-----PQSALSTTLSPG 549
+P P +G+ G +G +G P SP P P P P S + ++L PG
Sbjct: 115 APGP----QGIPGCN-GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSL-PG 168
Query: 550 PVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCL 609
P +P Y + P P P P+ P P L P P L PG + L
Sbjct: 169 PKGNPGYPGPPGIQGL----PGPTGIPGPIGPPGPPGLM--GPPGPPGL--PGPKGNMGL 220
Query: 610 PESYPYGSPQEKSLDKAGSESPHPG-----RRTPGNSSKKPSQGSGRRPGDPGSTPLRDR 664
P G E+ L G P PG +R +K QG G PG +R
Sbjct: 221 NFQGPKGEKGEQGLQ--GPPGP-PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR-- 275
Query: 665 LAALGKLKTGPEGALGSEK--NGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAK 722
GP G G EK G PG K PGK GE+ +P
Sbjct: 276 ---------GPPGPPGGEKGEKGEQGEPG--KRGKPGKDGENGQPGIP------------ 312
Query: 723 GGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCL-----TKVEL 777
G+ G +PG G+PG G + D P P + T + +
Sbjct: 313 -GLPG------------DPGYPGEPG----RDGEKGQKGDTGPPGPPGLVIPRPGTGITI 355
Query: 778 AKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAP-LVT 836
+ G +P P + G+ P LP V+ PG P
Sbjct: 356 GEKGNIG-----LPGLPGE-------KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403
Query: 837 KESPKPDKG------KGPPWADCGSTTAQSTPLVPGPTDPSQGP 874
+ K D+G GPP D G A P PGP P P
Sbjct: 404 ERGQKGDEGPPGISIPGPPGLD-GQPGAPGLPGPPGPAGPHIPP 446
Score = 44.7 bits (104), Expect = 6e-04
Identities = 78/309 (25%), Positives = 102/309 (33%), Gaps = 59/309 (19%)
Query: 1046 PKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAE 1105
P E G+ K P NG G + G PG P EPGR E +
Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPG-IPGLPGDPGYPG-EPGRDGEKGQKGDTGP 338
Query: 1106 PVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPS----KNLPKTK-PPRLDPPPGVPP 1160
P P G + +GI + G G P + P + PP L PPG
Sbjct: 339 PGPP------GLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAV 392
Query: 1161 ARPPPLTKVP-RRAHTLEREVPGIEELLVSGRHPSMPAFPAL--------LPAAPGHRGH 1211
PP P R + PGI S+P P L LP PG G
Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGI----------SIPGPPGLDGQPGAPGLPGPPGPAGP 442
Query: 1212 ETCPDDPCEDPGPT-PPVQLAKNWTFPNTRAAGSSSDP--------LMCPPRQ--LEGLP 1260
P D +PGP PP G D + PP Q L GLP
Sbjct: 443 HIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP 502
Query: 1261 RTPMALPVDRKRSQEPSRPSPTPQG----------PPFGGSRTPSTSDM------AEEGR 1304
P +L ++ ++ + P+G P F GS+ + ++G
Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGE 562
Query: 1305 VASGGPPGL 1313
+ S G PGL
Sbjct: 563 LGSPGAPGL 571
Score = 37.4 bits (85), Expect = 0.097
Identities = 76/332 (22%), Positives = 103/332 (31%), Gaps = 61/332 (18%)
Query: 1038 LPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRN-----GLVGPLQGCGKP--PGKPSSE 1090
LP + +P F P + P P GP G GP+ G G P PG P +
Sbjct: 1108 LPGTPGAKGQPGLPGF-PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166
Query: 1091 ----------PGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFP---------- 1130
P ++ P + P P G + D G+ P
Sbjct: 1167 GKPGQDGIPGPAGQKGEPGQPGFGNPGPPG---LPGLSGQKGDGGLPGIPGNPGLPGPKG 1223
Query: 1131 -------PPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGI 1183
P G G P P + P+ +P P PP RP P +PG
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGN 1283
Query: 1184 EELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCE--------DPG-PTPPVQLAKNW 1234
+ +P P P LP G +G +P DPG P P
Sbjct: 1284 GGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG 1342
Query: 1235 TFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPS-------PTPQGP- 1286
+AG +P + P GLP + + + P P P PQGP
Sbjct: 1343 PSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQ 1402
Query: 1287 ----PFGGSRTPSTSDM-AEEGRVASGGPPGL 1313
P G P + + +G G PGL
Sbjct: 1403 GLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1434
Score = 35.0 bits (79), Expect = 0.48
Identities = 81/316 (25%), Positives = 98/316 (31%), Gaps = 79/316 (25%)
Query: 1055 PVSSDPKSPWPACGPRNGLVGP--LQGCGKPPGKPS-----SEPGRREEMPSEDSLAEPV 1107
P + P P P GP G VG +QG PG+P +PG+ P + L
Sbjct: 614 PGNIGPMGP-PGFGPP-GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671
Query: 1108 PTSHFTACGSLTRTLDSGIGTFP-----PPDHGSSGTPSKNLPKTKPPRLDP----PPGV 1158
G + D G+ P P G G P LP P+ P PPG
Sbjct: 672 GRD-----GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726
Query: 1159 P--PAR-----PPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALL--------- 1202
P P R PP P +PG P +P F L
Sbjct: 727 PGTPGRIGLEGPPGPPGFPGPKGEPGFALPG------PPGPPGLPGFKGALGPKGDRGFP 780
Query: 1203 --PAAPGHRGHETCPD-----DPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQ 1255
P PG G + P P PGP P L P G P + P
Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL------PGIGVQGPPGPPGIPGPIG 834
Query: 1256 LEGLPRTP----------MALPVDRKRSQEPSRP-SPTPQGPP--------FGGSRTPST 1296
GL P + +P P P +P P GPP G S P T
Sbjct: 835 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT 894
Query: 1297 SDMAEEGRVASGGPPG 1312
E G + GPPG
Sbjct: 895 K--GEMGMMGPPGPPG 908
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 77.4 bits (189), Expect = 8e-14
Identities = 218/850 (25%), Positives = 264/850 (31%), Gaps = 181/850 (21%)
Query: 115 LPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPP 174
LP P + P PP P +G P P G + + PG PG P P
Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGP-PGISIPGPPGLDGQ----PGAPGLPGPPG 438
Query: 175 PALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPG-------QGPGSPEPING 227
PA + P +D +C P P PPG QG + G
Sbjct: 439 PAGPHIPP-----------------SDE--ICEPGPP-GPPGSPGDKGLQGEQGVKGDKG 478
Query: 228 ELC------GPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPP 281
+ C G P P P L PG+LG G GE+ GP +G P
Sbjct: 479 DTCFNCIGTGISGPPGQPGLPGLPGPPGSLG--------FPGQKGEKGQAGATGP-KGLP 529
Query: 282 QAQGTSSGPNCAPGSSS-----------SSSSDEAGDPNEAPSPDTLLGALARRQLNLGQ 330
G P PGS E G P AP L G + L G
Sbjct: 530 GIPGAPGAPG-FPGSKGEPGDILTFPGMKGDKGELGSPG-APGLPGLPGTPGQDGLP-GL 586
Query: 331 LLEDTESYLQAFLAGAAGPLNGDHPG----PGQSSSPDQAPPQLSKSKGLPKSAWGGGTP 386
E F P N PG G P PP KG+ A G P
Sbjct: 587 PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQP 646
Query: 387 ----EAHRPGFGATSEGQGPLPFLSMFMG----AGDAPLGSRPGHPHSSSQVKSKLQIGP 438
PG T G+ LP G GD L +PG P SK + G
Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG---SKGEPGI 703
Query: 439 PSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPG-----GPQLSPQLPRNSRIPCRNSGS 493
P G LP P F +P +PG GP P P P
Sbjct: 704 PGIG------LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP--GFAL 755
Query: 494 DGSPSPLLARRGLGG--GELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPV 551
G P P GL G G L P+G +G P P P T L P+ + PGP+
Sbjct: 756 PGPPGP----PGLPGFKGALGPKGDRGFPGPPGPPGRT-GLDGLPGPKGDVGPNGQPGPM 810
Query: 552 VSPCYENILDLSRSTFRGPSPEPP--PSPLQVPTYPQLT----------LEVPQAPEVLR 599
P I +GP P PP P P+ P + L+VP P
Sbjct: 811 GPPGLPGI------GVQGP-PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863
Query: 600 SPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGST 659
SPG+P +P P G P L S PG K G PG PG
Sbjct: 864 SPGIPGAP-----GPIGPPGSPGLPGKAGASGFPG--------TKGEMGMMGPPGPPGPL 910
Query: 660 PLRDRLAALGKLK-----------TGPEGALGSE-KNGVPARPGTEKTRGPGKSGESAGD 707
+ R G LK GP G GS+ + G+P PG G GE
Sbjct: 911 GIPGRSGVPG-LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969
Query: 708 MVPSI--------HRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGA 759
+P I ++ L + G+ G L + PGL G PG
Sbjct: 970 GLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL---------- 1019
Query: 760 RVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNK-----SPHSS 814
+ P K + G + P P+ VP S G P + P S
Sbjct: 1020 ------IGPPG--LKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS 1071
Query: 815 PTKLPSKSPTKVVP----RPGAPLVTKESPKPDKG--KGPPWADCGSTTAQSTPLVPGPT 868
LP K P PG P + P G P A G P PGP
Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK-GQPGLPGFPGTPGPP 1130
Query: 869 DPS--QGPEG 876
P GP G
Sbjct: 1131 GPKGISGPPG 1140
Score = 76.3 bits (186), Expect = 2e-13
Identities = 209/829 (25%), Positives = 271/829 (32%), Gaps = 173/829 (20%)
Query: 116 PQIPLTPLQPPSEPPASPSLSSTEG----------PAAP-LPLGHCAGQREVCWEQQLRP 164
P +P +Q P PP P G P P L + G+R
Sbjct: 813 PGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER---------- 862
Query: 165 GGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQG--PG-- 220
G PG P AP P SP L KA E + P P PG+ PG
Sbjct: 863 GSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLK 922
Query: 221 SPEPINGE--LCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPS- 277
+ + G+ L GP + S P L PG + LLG G + + G P P
Sbjct: 923 GDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD-----PNLLGSKGEKGEPGLPGIPGV 977
Query: 278 RGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLN--LGQLLEDT 335
GP QG P PG S P P G + L +G +
Sbjct: 978 SGPKGYQGLPGDPG-QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM---- 1032
Query: 336 ESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGA 395
G GP + P PG S P Q S GLP G P G
Sbjct: 1033 ---------GFPGPQGVEGP-PGPSGVPGQPG-----SPGLPGQKGDKGDP-------GI 1070
Query: 396 TSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIG-PPSPGEAQGPLLPSPAR 454
+S G LP G+ L PG+P V G P +PG P LP
Sbjct: 1071 SSIGLPGLPGPK-----GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG--- 1122
Query: 455 GLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGG--GELS 512
PG P P P+ P N G G P P+ G GG G+
Sbjct: 1123 ---------------FPGTP--GPPGPKGISGPPGNPGLPGEPGPV----GGGGHPGQPG 1161
Query: 513 PEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSP 572
P G +G P P + P Q +PGP P LS G P
Sbjct: 1162 PPGEKGKPGQDG--IPGPAGQKGEPGQPGFG---NPGPPGLP------GLSGQKGDGGLP 1210
Query: 573 EPP-----PSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLD-KA 626
P P P P + P V PG P SP P G+P + +
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGF-------PGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRP 1263
Query: 627 GSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGV 686
G P PGN K +G+ +PG PG L+ GP G G+
Sbjct: 1264 GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG--------DQGPPGLQGN----- 1310
Query: 687 PARPGTEKTRG-PGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMG 745
P RPG +G PG G VP G++G + ++ + EPGL+G
Sbjct: 1311 PGRPGLNGMKGDPGLPG------VPGFP----------GMKGPSGVPGSAGPEGEPGLIG 1354
Query: 746 DPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLG 805
PG S + + P + L L G PQ P P G
Sbjct: 1355 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGL--KGLPGPQGPQGLPGPTGPPGDPGRNG 1412
Query: 806 KP---NKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTP 862
P LP + T+ + P P PD +GPP S+ A
Sbjct: 1413 LPGFDGAGGRKGDPGLPGQPGTRGLDGP---------PGPDGLQGPPGPPGTSSVAHGFL 1463
Query: 863 LV--PGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAEV 909
+ TD Q P+G +V +G ++L +QG +RA G ++
Sbjct: 1464 ITRHSQTTDAPQCPQGTL-------QVYEGF--SLLYVQGNKRAHGQDL 1503
Score = 75.9 bits (185), Expect = 2e-13
Identities = 199/818 (24%), Positives = 264/818 (32%), Gaps = 162/818 (19%)
Query: 125 PPSEP-----PASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDA 179
PP P P P + +G P + C G + ++ PG PG P P
Sbjct: 94 PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKG----ERGFPGSPGFPGLQGPPGPP 149
Query: 180 LSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPPQPEP-- 237
P ++ + + ++ +L P +P P P QG P I G + GPP P
Sbjct: 150 GIPGMKGEPGSI-IMSSL----PGPKGNPGYPGPPGIQGLPGPTGIPGPI-GPPGPPGLM 203
Query: 238 SPWAPCLLLGP-GNLGGLLHWERLLGGLGGEEDTGRPWGPS------------------- 277
P P L GP GN+G L+++ G G + G P P
Sbjct: 204 GPPGPPGLPGPKGNMG--LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261
Query: 278 ----RGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLE 333
RGPP G P P E G+P + P +
Sbjct: 262 LPGDRGPPGPPGIRGPPG--PPGGEKGEKGEQGEPGKRGKPG-----------------K 302
Query: 334 DTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGF 393
D E+ Q + G G PG P + + K P G P RPG
Sbjct: 303 DGENG-QPGIPGLPGD-------PGYPGEPGRDGEKGQKGDTGPPGPPGLVIP---RPGT 351
Query: 394 GAT--SEGQGPLPFLSMFMGAGDAP-LGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLP 450
G T +G LP L G P + PG P +GPP P G
Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAV----MGPPGPPGFPGERGQ 407
Query: 451 SPARGLKFLKLPPTSEKSPSPGGPQL-SPQLPRNSRIPCRNS-------GSDGSPSP--L 500
G + +P PG P L P P IP + G GSP L
Sbjct: 408 KGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL 467
Query: 501 LARRG------------LGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSP 548
+G +G G P G GLP P P P S + +
Sbjct: 468 QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGP----PGSLGFPGQKGEKGQAGAT 523
Query: 549 GPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPC 608
GP P F G EP + T+P + + + L SPG P P
Sbjct: 524 GPKGLPGIPGAP--GAPGFPGSKGEPG----DILTFPGMKGDKGE----LGSPGAPGLPG 573
Query: 609 LPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAAL 668
LP G+P + L G P + PG + K +G PG+PG L + +
Sbjct: 574 LP-----GTPGQDGLP--GLPGP---KGEPGGITFKGERGP---PGNPGLPGLPGNIGPM 620
Query: 669 GKLKTGPEGALGSEK-NGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQ-LEAKGGIR 726
G GP G +G + GV PG GP GD +I +P + L G
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGP------KGDPGQTITQPGKPGLPGNPGRD 674
Query: 727 GAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGAL 786
G V L + +PGL G PG++ EP P L K
Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKG------------EPGIPGIGLPGPPGPKGFPGIPG 722
Query: 787 CPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAP-----LVTKESPK 841
P P TP ++ P P P P P +P P P PK
Sbjct: 723 PPGAPGTPGRIGLEGPP------GPPGFPG--PKGEPGFALPGPPGPPGLPGFKGALGPK 774
Query: 842 PDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAP 879
D+G P G T P G P+ P + P
Sbjct: 775 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812
Score = 72.8 bits (177), Expect = 2e-12
Identities = 205/775 (26%), Positives = 241/775 (31%), Gaps = 203/775 (26%)
Query: 214 PPGQGPGSPEPINGELCGPPQPEPSPWAP----CLLLGPGNLGGLLHWERLLGGLGGEED 269
PPG PG+P I E GPP P P L GP GL ++ LG G
Sbjct: 723 PPG-APGTPGRIGLE--GPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779
Query: 270 TGRPWGPSR----GPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQ 325
G P P R G P +G GPN PG G P P + G + +
Sbjct: 780 PGPPGPPGRTGLDGLPGPKG-DVGPNGQPGPMGPPGLPGIGVQGP-PGPPGIPGPIGQPG 837
Query: 326 LNLGQLLEDTESYLQAFLAGAAGPLNGDHPGP-GQSSSPD--QAPPQLSK--SKGLPKSA 380
L+ G E G GP D PGP G+ SP AP + S GLP A
Sbjct: 838 LH-GIPGEK----------GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKA 886
Query: 381 WGGGTPEAH-RPGFGATSEGQGPL--PFLSMFMGA-GDAPLGSRPGHPHSSSQVKSKLQI 436
G P G GPL P S G GD L +PG P + + SK +
Sbjct: 887 GASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP 946
Query: 437 GPPSP------------GEAQGPLLPSPARGLKFLKLPPTSEKSPS-PGGPQLS--PQLP 481
G P P GE P LP G+ + P + P PG P LS P LP
Sbjct: 947 GLPGPPGPMDPNLLGSKGEKGEPGLP----GIPGVSGPKGYQGLPGDPGQPGLSGQPGLP 1002
Query: 482 RNSRIPCRNSGSDGSPSPLLARRGLGG--GELSPEGAQGL--PTSPSPCYTTPDSTQLRP 537
P N G G P L+ GL G G++ G QG+ P PS P S L
Sbjct: 1003 GPPG-PKGNPGLPGQPG-LIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL-- 1058
Query: 538 PQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEP-----PPSP-----LQVPTYPQL 587
PG I + GP EP P +P + P P L
Sbjct: 1059 ----------PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGL 1108
Query: 588 TLEVPQAPEVLRSPGVPPSPCLPE-------SYPYGSPQEKSLDKAGSESPHPGRRTPGN 640
P P PG+P P P S P G+P HPG+ P
Sbjct: 1109 ----PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164
Query: 641 SSKKPSQ-------GSGRRPGDPG-STPLRDRLAALGKLK-------------------- 672
KP Q G PG PG P L L K
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224
Query: 673 ---------TGPEGALGSE------------KNGVPARPGTEKTRGP-------GKSGES 704
GP G GS G P RPG GP G GE
Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEK 1284
Query: 705 AGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLE 764
P L L G +G L N + G+ GDPG
Sbjct: 1285 GNPGQPG----LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPG---------------- 1324
Query: 765 PVSPRSCLTKVELAKSRLAGALCPQVP-----RTPAKVPTSAPSLGKPNKSPHSSPTKLP 819
P VP + P+ VP SA G+P P LP
Sbjct: 1325 ----------------------LPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLP 1362
Query: 820 SKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGP 874
S G ++ K P G P G Q +PGPT P P
Sbjct: 1363 GPS--------GQSIIIKGDAGPPGIPGQPGLK-GLPGPQGPQGLPGPTGPPGDP 1408
Score = 56.2 bits (134), Expect = 2e-07
Identities = 182/713 (25%), Positives = 226/713 (31%), Gaps = 162/713 (22%)
Query: 208 PATPWRPPGQGPGSPEPINGE--LCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLG 265
P P P +GP P G+ + GPP P+ P L PG G L G+
Sbjct: 59 PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPG--------LPGMP 110
Query: 266 GEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQ 325
G + G P GP +G P GT G PGS P P
Sbjct: 111 GHD--GAP-GP-QGIPGCNGTK-GERGFPGSPGFPGLQGPPGPPGIPG------------ 153
Query: 326 LNLGQLLEDTESYLQAFLAGAAGPLNGDHPGP-GQSSSPDQAPPQLSKSKGLPKSAWGGG 384
+ + S + + L G G N +PGP G P P + G P G
Sbjct: 154 -----MKGEPGSIIMSSLPGPKG--NPGYPGPPGIQGLP--GPTGIPGPIGPPGPPGLMG 204
Query: 385 TPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQI-------- 436
P PG G L F G+ L PG P S+ K + +
Sbjct: 205 PPGP--PGLPGPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261
Query: 437 -----GPPSPGEAQGPLLPSPARGLKFLK----------LPPTSEKSPSPGGPQLSPQLP 481
GPP P +GP P P G K K P ++ PG P L P P
Sbjct: 262 LPGDRGPPGPPGIRGP--PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL-PGDP 318
Query: 482 RNSRIPCRN--------SGSDGSPSPLLARRGLGG--GELSPEGAQGLPTSPS----PCY 527
P R+ +G G P ++ R G G GE G GLP P
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI 378
Query: 528 TTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQL 587
P PP +A+ PGP P RG + P + +P P L
Sbjct: 379 QGPPGLP-GPPGAAVMGP--PGPPGFPGE-----------RGQKGDEGPPGISIPGPPGL 424
Query: 588 TLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQ 647
+ P AP + PG P P +P S E PG P
Sbjct: 425 DGQ-PGAPGLPGPPG-PAGPHIPPS---------------DEICEPGPPGP--------- 458
Query: 648 GSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGD 707
PG PG L+ G +G+ +G P +PG GP S G
Sbjct: 459 -----PGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513
Query: 708 MVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVS 767
KG A A G L PG+ G PGA + S G D+
Sbjct: 514 --------------KGEKGQAGATGPKGL----PGIPGAPGAPGFPG-SKGEPGDI-LTF 553
Query: 768 PRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVV 827
P K EL G P +P TP + P L P P + K
Sbjct: 554 PGMKGDKGELGSPGAPG--LPGLPGTPGQ--DGLPGL----PGPKGEPGGITFKGERGPP 605
Query: 828 PRPGAP-LVTKESPKPDKGKGPPWADCGSTTAQST------PLVPGPT-DPSQ 872
PG P L P G GPP G Q P +PGP DP Q
Sbjct: 606 GNPGLPGLPGNIGPMGPPGFGPP-GPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657
Score = 53.1 bits (126), Expect = 2e-06
Identities = 123/464 (26%), Positives = 160/464 (34%), Gaps = 112/464 (24%)
Query: 437 GPPSP-GEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDG 495
GPP P G+ +P P G K ++ PP P G P L P +P G DG
Sbjct: 69 GPPGPRGQKGDDGIPGPP-GPKGIRGPPGLPGFP--GTPGL-PGMP----------GHDG 114
Query: 496 SPSPLLARRGLGGGELSPEGAQGLPTSPS-PCYTTPDSTQLRP-----PQSALSTTLSPG 549
+P P +G+ G +G +G P SP P P P P S + ++L PG
Sbjct: 115 APGP----QGIPGCN-GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSL-PG 168
Query: 550 PVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCL 609
P +P Y + P P P P+ P P L P P L PG + L
Sbjct: 169 PKGNPGYPGPPGIQGL----PGPTGIPGPIGPPGPPGLM--GPPGPPGL--PGPKGNMGL 220
Query: 610 PESYPYGSPQEKSLDKAGSESPHPG-----RRTPGNSSKKPSQGSGRRPGDPGSTPLRDR 664
P G E+ L G P PG +R +K QG G PG +R
Sbjct: 221 NFQGPKGEKGEQGLQ--GPPGP-PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR-- 275
Query: 665 LAALGKLKTGPEGALGSEK--NGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAK 722
GP G G EK G PG K PGK GE+ +P
Sbjct: 276 ---------GPPGPPGGEKGEKGEQGEPG--KRGKPGKDGENGQPGIP------------ 312
Query: 723 GGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCL-----TKVEL 777
G+ G +PG G+PG G + D P P + T + +
Sbjct: 313 -GLPG------------DPGYPGEPG----RDGEKGQKGDTGPPGPPGLVIPRPGTGITI 355
Query: 778 AKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAP-LVT 836
+ G +P P + G+ P LP V+ PG P
Sbjct: 356 GEKGNIG-----LPGLPGE-------KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403
Query: 837 KESPKPDKG------KGPPWADCGSTTAQSTPLVPGPTDPSQGP 874
+ K D+G GPP D G A P PGP P P
Sbjct: 404 ERGQKGDEGPPGISIPGPPGLD-GQPGAPGLPGPPGPAGPHIPP 446
Score = 44.7 bits (104), Expect = 6e-04
Identities = 78/309 (25%), Positives = 102/309 (33%), Gaps = 59/309 (19%)
Query: 1046 PKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAE 1105
P E G+ K P NG G + G PG P EPGR E +
Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPG-IPGLPGDPGYPG-EPGRDGEKGQKGDTGP 338
Query: 1106 PVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPS----KNLPKTK-PPRLDPPPGVPP 1160
P P G + +GI + G G P + P + PP L PPG
Sbjct: 339 PGPP------GLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAV 392
Query: 1161 ARPPPLTKVP-RRAHTLEREVPGIEELLVSGRHPSMPAFPAL--------LPAAPGHRGH 1211
PP P R + PGI S+P P L LP PG G
Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGI----------SIPGPPGLDGQPGAPGLPGPPGPAGP 442
Query: 1212 ETCPDDPCEDPGPT-PPVQLAKNWTFPNTRAAGSSSDP--------LMCPPRQ--LEGLP 1260
P D +PGP PP G D + PP Q L GLP
Sbjct: 443 HIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP 502
Query: 1261 RTPMALPVDRKRSQEPSRPSPTPQG----------PPFGGSRTPSTSDM------AEEGR 1304
P +L ++ ++ + P+G P F GS+ + ++G
Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGE 562
Query: 1305 VASGGPPGL 1313
+ S G PGL
Sbjct: 563 LGSPGAPGL 571
Score = 35.0 bits (79), Expect = 0.48
Identities = 81/316 (25%), Positives = 98/316 (31%), Gaps = 79/316 (25%)
Query: 1055 PVSSDPKSPWPACGPRNGLVGP--LQGCGKPPGKPS-----SEPGRREEMPSEDSLAEPV 1107
P + P P P GP G VG +QG PG+P +PG+ P + L
Sbjct: 614 PGNIGPMGP-PGFGPP-GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671
Query: 1108 PTSHFTACGSLTRTLDSGIGTFP-----PPDHGSSGTPSKNLPKTKPPRLDP----PPGV 1158
G + D G+ P P G G P LP P+ P PPG
Sbjct: 672 GRD-----GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726
Query: 1159 P--PAR-----PPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALL--------- 1202
P P R PP P +PG P +P F L
Sbjct: 727 PGTPGRIGLEGPPGPPGFPGPKGEPGFALPG------PPGPPGLPGFKGALGPKGDRGFP 780
Query: 1203 --PAAPGHRGHETCPD-----DPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQ 1255
P PG G + P P PGP P L P G P + P
Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL------PGIGVQGPPGPPGIPGPIG 834
Query: 1256 LEGLPRTP----------MALPVDRKRSQEPSRP-SPTPQGPP--------FGGSRTPST 1296
GL P + +P P P +P P GPP G S P T
Sbjct: 835 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT 894
Query: 1297 SDMAEEGRVASGGPPG 1312
E G + GPPG
Sbjct: 895 K--GEMGMMGPPGPPG 908
Score = 34.3 bits (77), Expect = 0.82
Identities = 77/333 (23%), Positives = 105/333 (31%), Gaps = 69/333 (20%)
Query: 1038 LPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRN-----GLVGPLQGCGKP--PGKPSSE 1090
LP + +P F P + P P GP G GP+ G G P PG P +
Sbjct: 1108 LPGTPGAKGQPGLPGF-PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166
Query: 1091 ----------PGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFP---------- 1130
P ++ P + P P G + D G+ P
Sbjct: 1167 GKPGQDGIPGPAGQKGEPGQPGFGNPGPPG---LPGLSGQKGDGGLPGIPGNPGLPGPKG 1223
Query: 1131 -------PPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPP-PLTKVPRRAHTLEREVPG 1182
P G G P P + P+ +P P PP RP P + P +PG
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGP-------PGLPG 1276
Query: 1183 IEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCE--------DPG-PTPPVQLAKN 1233
+ +P P P LP G +G +P DPG P P
Sbjct: 1277 NGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMK 1335
Query: 1234 WTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPS-------PTPQGP 1286
+AG +P + P GLP + + + P P P PQGP
Sbjct: 1336 GPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP 1395
Query: 1287 -----PFGGSRTPSTSDM-AEEGRVASGGPPGL 1313
P G P + + +G G PGL
Sbjct: 1396 QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1428
>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
sapiens]
Length = 1688
Score = 77.4 bits (189), Expect = 8e-14
Identities = 218/850 (25%), Positives = 264/850 (31%), Gaps = 181/850 (21%)
Query: 115 LPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPP 174
LP P + P PP P +G P P G + + PG PG P P
Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGP-PGISIPGPPGLDGQ----PGAPGLPGPPG 438
Query: 175 PALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPG-------QGPGSPEPING 227
PA + P +D +C P P PPG QG + G
Sbjct: 439 PAGPHIPP-----------------SDE--ICEPGPP-GPPGSPGDKGLQGEQGVKGDKG 478
Query: 228 ELC------GPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPP 281
+ C G P P P L PG+LG G GE+ GP +G P
Sbjct: 479 DTCFNCIGTGISGPPGQPGLPGLPGPPGSLG--------FPGQKGEKGQAGATGP-KGLP 529
Query: 282 QAQGTSSGPNCAPGSSS-----------SSSSDEAGDPNEAPSPDTLLGALARRQLNLGQ 330
G P PGS E G P AP L G + L G
Sbjct: 530 GIPGAPGAPG-FPGSKGEPGDILTFPGMKGDKGELGSPG-APGLPGLPGTPGQDGLP-GL 586
Query: 331 LLEDTESYLQAFLAGAAGPLNGDHPG----PGQSSSPDQAPPQLSKSKGLPKSAWGGGTP 386
E F P N PG G P PP KG+ A G P
Sbjct: 587 PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQP 646
Query: 387 ----EAHRPGFGATSEGQGPLPFLSMFMG----AGDAPLGSRPGHPHSSSQVKSKLQIGP 438
PG T G+ LP G GD L +PG P SK + G
Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG---SKGEPGI 703
Query: 439 PSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPG-----GPQLSPQLPRNSRIPCRNSGS 493
P G LP P F +P +PG GP P P P
Sbjct: 704 PGIG------LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP--GFAL 755
Query: 494 DGSPSPLLARRGLGG--GELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPV 551
G P P GL G G L P+G +G P P P T L P+ + PGP+
Sbjct: 756 PGPPGP----PGLPGFKGALGPKGDRGFPGPPGPPGRT-GLDGLPGPKGDVGPNGQPGPM 810
Query: 552 VSPCYENILDLSRSTFRGPSPEPP--PSPLQVPTYPQLT----------LEVPQAPEVLR 599
P I +GP P PP P P+ P + L+VP P
Sbjct: 811 GPPGLPGI------GVQGP-PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863
Query: 600 SPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGST 659
SPG+P +P P G P L S PG K G PG PG
Sbjct: 864 SPGIPGAP-----GPIGPPGSPGLPGKAGASGFPG--------TKGEMGMMGPPGPPGPL 910
Query: 660 PLRDRLAALGKLK-----------TGPEGALGSE-KNGVPARPGTEKTRGPGKSGESAGD 707
+ R G LK GP G GS+ + G+P PG G GE
Sbjct: 911 GIPGRSGVPG-LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969
Query: 708 MVPSI--------HRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGA 759
+P I ++ L + G+ G L + PGL G PG
Sbjct: 970 GLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL---------- 1019
Query: 760 RVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNK-----SPHSS 814
+ P K + G + P P+ VP S G P + P S
Sbjct: 1020 ------IGPPG--LKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS 1071
Query: 815 PTKLPSKSPTKVVP----RPGAPLVTKESPKPDKG--KGPPWADCGSTTAQSTPLVPGPT 868
LP K P PG P + P G P A G P PGP
Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK-GQPGLPGFPGTPGPP 1130
Query: 869 DPS--QGPEG 876
P GP G
Sbjct: 1131 GPKGISGPPG 1140
Score = 75.9 bits (185), Expect = 2e-13
Identities = 199/818 (24%), Positives = 264/818 (32%), Gaps = 162/818 (19%)
Query: 125 PPSEP-----PASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDA 179
PP P P P + +G P + C G + ++ PG PG P P
Sbjct: 94 PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKG----ERGFPGSPGFPGLQGPPGPP 149
Query: 180 LSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPPQPEP-- 237
P ++ + + ++ +L P +P P P QG P I G + GPP P
Sbjct: 150 GIPGMKGEPGSI-IMSSL----PGPKGNPGYPGPPGIQGLPGPTGIPGPI-GPPGPPGLM 203
Query: 238 SPWAPCLLLGP-GNLGGLLHWERLLGGLGGEEDTGRPWGPS------------------- 277
P P L GP GN+G L+++ G G + G P P
Sbjct: 204 GPPGPPGLPGPKGNMG--LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261
Query: 278 ----RGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLE 333
RGPP G P P E G+P + P +
Sbjct: 262 LPGDRGPPGPPGIRGPPG--PPGGEKGEKGEQGEPGKRGKPG-----------------K 302
Query: 334 DTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGF 393
D E+ Q + G G PG P + + K P G P RPG
Sbjct: 303 DGENG-QPGIPGLPGD-------PGYPGEPGRDGEKGQKGDTGPPGPPGLVIP---RPGT 351
Query: 394 GAT--SEGQGPLPFLSMFMGAGDAP-LGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLP 450
G T +G LP L G P + PG P +GPP P G
Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAV----MGPPGPPGFPGERGQ 407
Query: 451 SPARGLKFLKLPPTSEKSPSPGGPQL-SPQLPRNSRIPCRNS-------GSDGSPSP--L 500
G + +P PG P L P P IP + G GSP L
Sbjct: 408 KGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL 467
Query: 501 LARRG------------LGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSP 548
+G +G G P G GLP P P P S + +
Sbjct: 468 QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGP----PGSLGFPGQKGEKGQAGAT 523
Query: 549 GPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPC 608
GP P F G EP + T+P + + + L SPG P P
Sbjct: 524 GPKGLPGIPGAP--GAPGFPGSKGEPG----DILTFPGMKGDKGE----LGSPGAPGLPG 573
Query: 609 LPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAAL 668
LP G+P + L G P + PG + K +G PG+PG L + +
Sbjct: 574 LP-----GTPGQDGLP--GLPGP---KGEPGGITFKGERGP---PGNPGLPGLPGNIGPM 620
Query: 669 GKLKTGPEGALGSEK-NGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQ-LEAKGGIR 726
G GP G +G + GV PG GP GD +I +P + L G
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGP------KGDPGQTITQPGKPGLPGNPGRD 674
Query: 727 GAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGAL 786
G V L + +PGL G PG++ EP P L K
Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKG------------EPGIPGIGLPGPPGPKGFPGIPG 722
Query: 787 CPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAP-----LVTKESPK 841
P P TP ++ P P P P P +P P P PK
Sbjct: 723 PPGAPGTPGRIGLEGPP------GPPGFPG--PKGEPGFALPGPPGPPGLPGFKGALGPK 774
Query: 842 PDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAP 879
D+G P G T P G P+ P + P
Sbjct: 775 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812
Score = 73.9 bits (180), Expect = 9e-13
Identities = 213/835 (25%), Positives = 273/835 (32%), Gaps = 182/835 (21%)
Query: 116 PQIPLTPLQPPSEPPASPSLSSTEG----------PAAP-LPLGHCAGQREVCWEQQLRP 164
P +P +Q P PP P G P P L + G+R
Sbjct: 813 PGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER---------- 862
Query: 165 GGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQG--PG-- 220
G PG P AP P SP L KA E + P P PG+ PG
Sbjct: 863 GSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLK 922
Query: 221 SPEPINGE--LCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPS- 277
+ + G+ L GP + S P L PG + LLG G + + G P P
Sbjct: 923 GDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD-----PNLLGSKGEKGEPGLPGIPGV 977
Query: 278 RGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLN--LGQLLEDT 335
GP QG P PG S P P G + L +G +
Sbjct: 978 SGPKGYQGLPGDPG-QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM---- 1032
Query: 336 ESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGA 395
G GP + P PG S P Q S GLP G P G
Sbjct: 1033 ---------GFPGPQGVEGP-PGPSGVPGQPG-----SPGLPGQKGDKGDP-------GI 1070
Query: 396 TSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIG-PPSPGEAQGPLLPSPAR 454
+S G LP G+ L PG+P V G P +PG P LP
Sbjct: 1071 SSIGLPGLPGPK-----GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG--- 1122
Query: 455 GLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGG--GELS 512
PG P P P+ P N G G P P+ G GG G+
Sbjct: 1123 ---------------FPGTP--GPPGPKGISGPPGNPGLPGEPGPV----GGGGHPGQPG 1161
Query: 513 PEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSP 572
P G +G P P + P Q +PGP P LS G P
Sbjct: 1162 PPGEKGKPGQDG--IPGPAGQKGEPGQPGFG---NPGPPGLP------GLSGQKGDGGLP 1210
Query: 573 EPP-----PSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKS----- 622
P P P P + P V PG P SP P G+P +
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGF-------PGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRP 1263
Query: 623 --LDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALG 680
G E P PG PGN K +G+ +PG PG L K GP G G
Sbjct: 1264 GFQGLPGPEGP-PG--LPGNGGIKGEKGNPGQPGLPGLPGL--------KGDQGPPGLQG 1312
Query: 681 SEKNGVPARPGTEKTRG-PGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQ 739
+ P RPG +G PG G VP G++G + ++ +
Sbjct: 1313 N-----PGRPGLNGMKGDPGLPG------VPGF----------PGMKGPSGVPGSAGPEG 1351
Query: 740 EPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPT 799
EPGL+G PG S + + P + L L G PQ P P
Sbjct: 1352 EPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGL--KGLPGPQGPQGLPGPTGPPG 1409
Query: 800 SAPSLGKP---NKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGST 856
G P LP + T+ + P P PD +GPP S+
Sbjct: 1410 DPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP---------PGPDGLQGPPGPPGTSS 1460
Query: 857 TAQSTPLV--PGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERAPGAEV 909
A + TD Q P+G +V +G ++L +QG +RA G ++
Sbjct: 1461 VAHGFLITRHSQTTDAPQCPQGTL-------QVYEGF--SLLYVQGNKRAHGQDL 1506
Score = 56.2 bits (134), Expect = 2e-07
Identities = 182/713 (25%), Positives = 226/713 (31%), Gaps = 162/713 (22%)
Query: 208 PATPWRPPGQGPGSPEPINGE--LCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLG 265
P P P +GP P G+ + GPP P+ P L PG G L G+
Sbjct: 59 PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPG--------LPGMP 110
Query: 266 GEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQ 325
G + G P GP +G P GT G PGS P P
Sbjct: 111 GHD--GAP-GP-QGIPGCNGTK-GERGFPGSPGFPGLQGPPGPPGIPG------------ 153
Query: 326 LNLGQLLEDTESYLQAFLAGAAGPLNGDHPGP-GQSSSPDQAPPQLSKSKGLPKSAWGGG 384
+ + S + + L G G N +PGP G P P + G P G
Sbjct: 154 -----MKGEPGSIIMSSLPGPKG--NPGYPGPPGIQGLP--GPTGIPGPIGPPGPPGLMG 204
Query: 385 TPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQI-------- 436
P PG G L F G+ L PG P S+ K + +
Sbjct: 205 PPGP--PGLPGPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261
Query: 437 -----GPPSPGEAQGPLLPSPARGLKFLK----------LPPTSEKSPSPGGPQLSPQLP 481
GPP P +GP P P G K K P ++ PG P L P P
Sbjct: 262 LPGDRGPPGPPGIRGP--PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL-PGDP 318
Query: 482 RNSRIPCRN--------SGSDGSPSPLLARRGLGG--GELSPEGAQGLPTSPS----PCY 527
P R+ +G G P ++ R G G GE G GLP P
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI 378
Query: 528 TTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQL 587
P PP +A+ PGP P RG + P + +P P L
Sbjct: 379 QGPPGLP-GPPGAAVMGP--PGPPGFPGE-----------RGQKGDEGPPGISIPGPPGL 424
Query: 588 TLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQ 647
+ P AP + PG P P +P S E PG P
Sbjct: 425 DGQ-PGAPGLPGPPG-PAGPHIPPS---------------DEICEPGPPGP--------- 458
Query: 648 GSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGD 707
PG PG L+ G +G+ +G P +PG GP S G
Sbjct: 459 -----PGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513
Query: 708 MVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVS 767
KG A A G L PG+ G PGA + S G D+
Sbjct: 514 --------------KGEKGQAGATGPKGL----PGIPGAPGAPGFPG-SKGEPGDI-LTF 553
Query: 768 PRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVV 827
P K EL G P +P TP + P L P P + K
Sbjct: 554 PGMKGDKGELGSPGAPG--LPGLPGTPGQ--DGLPGL----PGPKGEPGGITFKGERGPP 605
Query: 828 PRPGAP-LVTKESPKPDKGKGPPWADCGSTTAQST------PLVPGPT-DPSQ 872
PG P L P G GPP G Q P +PGP DP Q
Sbjct: 606 GNPGLPGLPGNIGPMGPPGFGPP-GPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657
Score = 53.1 bits (126), Expect = 2e-06
Identities = 123/464 (26%), Positives = 160/464 (34%), Gaps = 112/464 (24%)
Query: 437 GPPSP-GEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDG 495
GPP P G+ +P P G K ++ PP P G P L P +P G DG
Sbjct: 69 GPPGPRGQKGDDGIPGPP-GPKGIRGPPGLPGFP--GTPGL-PGMP----------GHDG 114
Query: 496 SPSPLLARRGLGGGELSPEGAQGLPTSPS-PCYTTPDSTQLRP-----PQSALSTTLSPG 549
+P P +G+ G +G +G P SP P P P P S + ++L PG
Sbjct: 115 APGP----QGIPGCN-GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSL-PG 168
Query: 550 PVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCL 609
P +P Y + P P P P+ P P L P P L PG + L
Sbjct: 169 PKGNPGYPGPPGIQGL----PGPTGIPGPIGPPGPPGLM--GPPGPPGL--PGPKGNMGL 220
Query: 610 PESYPYGSPQEKSLDKAGSESPHPG-----RRTPGNSSKKPSQGSGRRPGDPGSTPLRDR 664
P G E+ L G P PG +R +K QG G PG +R
Sbjct: 221 NFQGPKGEKGEQGLQ--GPPGP-PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR-- 275
Query: 665 LAALGKLKTGPEGALGSEK--NGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAK 722
GP G G EK G PG K PGK GE+ +P
Sbjct: 276 ---------GPPGPPGGEKGEKGEQGEPG--KRGKPGKDGENGQPGIP------------ 312
Query: 723 GGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCL-----TKVEL 777
G+ G +PG G+PG G + D P P + T + +
Sbjct: 313 -GLPG------------DPGYPGEPG----RDGEKGQKGDTGPPGPPGLVIPRPGTGITI 355
Query: 778 AKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAP-LVT 836
+ G +P P + G+ P LP V+ PG P
Sbjct: 356 GEKGNIG-----LPGLPGE-------KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403
Query: 837 KESPKPDKG------KGPPWADCGSTTAQSTPLVPGPTDPSQGP 874
+ K D+G GPP D G A P PGP P P
Sbjct: 404 ERGQKGDEGPPGISIPGPPGLD-GQPGAPGLPGPPGPAGPHIPP 446
Score = 44.7 bits (104), Expect = 6e-04
Identities = 78/309 (25%), Positives = 102/309 (33%), Gaps = 59/309 (19%)
Query: 1046 PKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAE 1105
P E G+ K P NG G + G PG P EPGR E +
Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPG-IPGLPGDPGYPG-EPGRDGEKGQKGDTGP 338
Query: 1106 PVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPS----KNLPKTK-PPRLDPPPGVPP 1160
P P G + +GI + G G P + P + PP L PPG
Sbjct: 339 PGPP------GLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAV 392
Query: 1161 ARPPPLTKVP-RRAHTLEREVPGIEELLVSGRHPSMPAFPAL--------LPAAPGHRGH 1211
PP P R + PGI S+P P L LP PG G
Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGI----------SIPGPPGLDGQPGAPGLPGPPGPAGP 442
Query: 1212 ETCPDDPCEDPGPT-PPVQLAKNWTFPNTRAAGSSSDP--------LMCPPRQ--LEGLP 1260
P D +PGP PP G D + PP Q L GLP
Sbjct: 443 HIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP 502
Query: 1261 RTPMALPVDRKRSQEPSRPSPTPQG----------PPFGGSRTPSTSDM------AEEGR 1304
P +L ++ ++ + P+G P F GS+ + ++G
Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGE 562
Query: 1305 VASGGPPGL 1313
+ S G PGL
Sbjct: 563 LGSPGAPGL 571
Score = 35.0 bits (79), Expect = 0.48
Identities = 81/316 (25%), Positives = 98/316 (31%), Gaps = 79/316 (25%)
Query: 1055 PVSSDPKSPWPACGPRNGLVGP--LQGCGKPPGKPS-----SEPGRREEMPSEDSLAEPV 1107
P + P P P GP G VG +QG PG+P +PG+ P + L
Sbjct: 614 PGNIGPMGP-PGFGPP-GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671
Query: 1108 PTSHFTACGSLTRTLDSGIGTFP-----PPDHGSSGTPSKNLPKTKPPRLDP----PPGV 1158
G + D G+ P P G G P LP P+ P PPG
Sbjct: 672 GRD-----GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726
Query: 1159 P--PAR-----PPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALL--------- 1202
P P R PP P +PG P +P F L
Sbjct: 727 PGTPGRIGLEGPPGPPGFPGPKGEPGFALPG------PPGPPGLPGFKGALGPKGDRGFP 780
Query: 1203 --PAAPGHRGHETCPD-----DPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQ 1255
P PG G + P P PGP P L P G P + P
Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL------PGIGVQGPPGPPGIPGPIG 834
Query: 1256 LEGLPRTP----------MALPVDRKRSQEPSRP-SPTPQGPP--------FGGSRTPST 1296
GL P + +P P P +P P GPP G S P T
Sbjct: 835 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT 894
Query: 1297 SDMAEEGRVASGGPPG 1312
E G + GPPG
Sbjct: 895 K--GEMGMMGPPGPPG 908
Score = 33.1 bits (74), Expect = 1.8
Identities = 77/336 (22%), Positives = 105/336 (31%), Gaps = 72/336 (21%)
Query: 1038 LPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRN-----GLVGPLQGCGKP--PGKPSSE 1090
LP + +P F P + P P GP G GP+ G G P PG P +
Sbjct: 1108 LPGTPGAKGQPGLPGF-PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166
Query: 1091 ----------PGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFP---------- 1130
P ++ P + P P G + D G+ P
Sbjct: 1167 GKPGQDGIPGPAGQKGEPGQPGFGNPGPPG---LPGLSGQKGDGGLPGIPGNPGLPGPKG 1223
Query: 1131 -------PPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPP----PLTKVPRRAHTLERE 1179
P G G P P + P+ +P P PP RP P + P
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGP-------PG 1276
Query: 1180 VPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCE--------DPG-PTPPVQL 1230
+PG + +P P P LP G +G +P DPG P P
Sbjct: 1277 LPGNGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFP 1335
Query: 1231 AKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPS-------PTP 1283
+AG +P + P GLP + + + P P P P
Sbjct: 1336 GMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP 1395
Query: 1284 QGP-----PFGGSRTPSTSDM-AEEGRVASGGPPGL 1313
QGP P G P + + +G G PGL
Sbjct: 1396 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1431
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 77.0 bits (188), Expect = 1e-13
Identities = 115/445 (25%), Positives = 131/445 (29%), Gaps = 99/445 (22%)
Query: 119 PLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALD 178
P P PP +P P + P P G G + P PG P PPP D
Sbjct: 47 PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 106
Query: 179 ALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQG---PGSPEPINGELCGP--- 232
++ P P P PP QG P P P G+ GP
Sbjct: 107 ----------------KSRSPRSP-----PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 145
Query: 233 ----PQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSS 288
PQ P P P GP G G+P GP PPQ
Sbjct: 146 GGNKPQGPPPPGKP---QGPPPQGD-------NKSRSSRSPPGKPQGP---PPQGGNQPQ 192
Query: 289 GPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAG 348
GP PG P P P G + N Q Q
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD-NKSQSARSPPGKPQGPPPQGGN 251
Query: 349 PLNGDHPGPGQSSSP-------DQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQG 401
G P PG+ P Q PP K +G P PG + QG
Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPG-----KPQG 306
Query: 402 PLPFLSMFMGAGDAPLG--SRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFL 459
P P G+ P G PG P GPP PG+ QG P P G K
Sbjct: 307 PPP------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGGSK-- 355
Query: 460 KLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEG---- 515
S +SP PG PQ PQ N+ G P P GG P+
Sbjct: 356 ---SRSARSP-PGKPQGPPQQEGNN--------PQGPPPP------AGGNPQQPQAPPAG 397
Query: 516 -AQGLPTSPSPCYTTPDSTQLRPPQ 539
QG P P RPPQ
Sbjct: 398 QPQGPPRPPQ------GGRPSRPPQ 416
Score = 70.5 bits (171), Expect = 1e-11
Identities = 107/437 (24%), Positives = 139/437 (31%), Gaps = 82/437 (18%)
Query: 265 GGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARR 324
G G+P GP PPQ GP PG P P P G +
Sbjct: 49 GPPSPPGKPQGP---PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 105
Query: 325 QLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGG 384
+ + + P P P + P PP K +G P GG
Sbjct: 106 DKS---------------RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ--GGN 148
Query: 385 TPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEA 444
P+ P + QGP P + +P G G P Q ++ Q PP PG+
Sbjct: 149 KPQGPPP----PGKPQGPPPQGDNKSRSSRSPPGKPQGPP---PQGGNQPQGPPPPPGKP 201
Query: 445 QGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRN-SGSDGSPSPLLAR 503
QG P P G K + P PG PQ P N R+ G P P
Sbjct: 202 QG---PPPQGGNK-------PQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP---- 247
Query: 504 RGLGGGELSPEGAQGLPTSPSP-------CYTTPDSTQLRPPQSALSTTLSPGPVVSPCY 556
+G G P G P P P P Q PPQ + S P P
Sbjct: 248 QG-GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKP-- 304
Query: 557 ENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYG 616
+GP P+ P P P P P+ P PP P P+ P
Sbjct: 305 -----------QGPPPQGGNQPQGPPPPPGKPQGPP--PQGGNKPQGPPPPGKPQGPP-- 349
Query: 617 SPQEKSLDKAGSESPHPGRRTP---GNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKT 673
PQ S ++ P + P GN+ + P +G P P + P
Sbjct: 350 -PQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ---------- 398
Query: 674 GPEGALGSEKNGVPARP 690
P+G + G P+RP
Sbjct: 399 -PQGPPRPPQGGRPSRP 414
Score = 65.1 bits (157), Expect = 4e-10
Identities = 127/521 (24%), Positives = 156/521 (29%), Gaps = 160/521 (30%)
Query: 360 SSSPDQAPPQL-SKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLG 418
+ +P APPQ +K +G P G P+ P G ++ QGP P
Sbjct: 33 AGNPQGAPPQGGNKPQGPPSPP---GKPQGPPPQGG--NQPQGPPP-------------- 73
Query: 419 SRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSP 478
PG P GPP PG+ QGP PP +KS SP P P
Sbjct: 74 -PPGKPQGPPPQGGNKPQGPPPPGKPQGP--------------PPQGDKSRSPRSPPGKP 118
Query: 479 QLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPP 538
Q P P + G P P +G P P P P P Q PP
Sbjct: 119 QGPP----PQGGNQPQGPPPPPGKPQG------PPPQGGNKPQGPPP----PGKPQGPPP 164
Query: 539 QS---ALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAP 595
Q + S+ PG P + G P+ PP P P P P
Sbjct: 165 QGDNKSRSSRSPPGKPQGPPPQG----------GNQPQGPPPPPGKPQGPP--------P 206
Query: 596 EVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGD 655
+ P PP P P+ P PQ G R PG P QG G +P
Sbjct: 207 QGGNKPQGPPPPGKPQGPP---PQ-------GDNKSQSARSPPGKPQGPPPQG-GNQPQG 255
Query: 656 PGSTPLRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHRP 715
P P GK P+G P G K +GP G
Sbjct: 256 PPPPP--------GK----PQG---------PPPQGGNKPQGPPPPG------------- 281
Query: 716 LEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKV 775
K Q P G G++ SS S + P
Sbjct: 282 ---------------------KPQGPPPQG--GSKSRSSRSPPGKPQGPPPQ-------- 310
Query: 776 ELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLV 835
G PQ P P P P G P P P P P+ G+
Sbjct: 311 --------GGNQPQGPPPPPGKPQGPPPQG--GNKPQGPP---PPGKPQGPPPQGGSKSR 357
Query: 836 TKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEG 876
+ SP P K +GPP + + P P P P G
Sbjct: 358 SARSP-PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG 397
Score = 55.5 bits (132), Expect = 3e-07
Identities = 87/316 (27%), Positives = 105/316 (33%), Gaps = 51/316 (16%)
Query: 997 PGGPAPGPNTGLGQVQGQLA--GMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQ 1054
PG P P G Q QG G QG Q N+ G P K + P GD
Sbjct: 54 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPP---QGGNKPQGPPPPGKP--QGPPPQGD-- 106
Query: 1055 PVSSDPKSP--WPACGPRNGLVGPLQGCGKPPGKPSSEP---GRREEMPSEDSLAEPVPT 1109
S P+SP P P G P QG PPGKP P G + + P + P
Sbjct: 107 -KSRSPRSPPGKPQGPPPQGGNQP-QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 164
Query: 1110 SHFTACGSLTRTLDSGIGTFPPPDHGSSGT---PSKNLPKTKPPRLD------PPPGVPP 1160
S + G PPP G+ P P+ PP+ PPPG P
Sbjct: 165 QGDNK--SRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 222
Query: 1161 ARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETC--PDDP 1218
PP + A + + G G P P P P P +G P P
Sbjct: 223 GPPPQGDNKSQSARSPPGKPQGPPPQ--GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 280
Query: 1219 CEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSR 1278
+ GP P GS S PP + +G P P + Q P
Sbjct: 281 GKPQGPPPQ--------------GGSKSRSSRSPPGKPQGPP------PQGGNQPQGPPP 320
Query: 1279 PSPTPQGPPFGGSRTP 1294
P PQGPP G P
Sbjct: 321 PPGKPQGPPPQGGNKP 336
Score = 54.7 bits (130), Expect = 6e-07
Identities = 100/394 (25%), Positives = 116/394 (29%), Gaps = 144/394 (36%)
Query: 113 GSLPQIPLTPLQPPSEPPASPSLSST--------EGP---------AAPLPLGHCAGQRE 155
G+ PQ P P +P PP + S + +GP P P G G
Sbjct: 147 GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206
Query: 156 VCWEQQLRPGGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPP 215
+ P PG P PPP D S R P P PP
Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARS--------------------PPGKPQGPP 246
Query: 216 GQGPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWG 275
QG P+ GPP P P GP GG +P G
Sbjct: 247 PQGGNQPQ-------GPPPPPGKP------QGPPPQGG-----------------NKPQG 276
Query: 276 PSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDT 335
P PP G GP GS S SS G P + P P
Sbjct: 277 P---PP--PGKPQGPPPQGGSKSRSSRSPPGKP-QGPPPQ-------------------- 310
Query: 336 ESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGA 395
G P G P PG+ P PPQ GG P+ P
Sbjct: 311 ---------GGNQP-QGPPPPPGKPQGP---PPQ------------GGNKPQGPPP---- 341
Query: 396 TSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSP--GEAQGPLLPSPA 453
+ QGP P G+ S PG P Q + GPP P G Q P
Sbjct: 342 PGKPQGPPP----QGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP------ 391
Query: 454 RGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIP 487
+ PP + P GP PQ R SR P
Sbjct: 392 ------QAPPAGQ----PQGPPRPPQGGRPSRPP 415
Score = 52.8 bits (125), Expect = 2e-06
Identities = 88/326 (26%), Positives = 105/326 (32%), Gaps = 48/326 (14%)
Query: 990 SSRARPRPGGPAPGPNTGLGQVQGQLA--GMYQGADTFMQQLLNRVDGKELPSKSWREPK 1047
S R PG P P G Q QG G QG Q N+ G P K +
Sbjct: 108 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP---QGGNKPQGPPPPGKP--QGP 162
Query: 1048 PEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPPGKPSSEP---GRREEMPSEDSLA 1104
P GD + SS P P G P QG PPGKP P G + + P
Sbjct: 163 PPQGDNKSRSSRSPPGKPQGPPPQGGNQP-QGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 221
Query: 1105 EPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGT---PSKNLPKTKPPR-----LDPPP 1156
+ P S G PPP G+ P P+ PP+ PPP
Sbjct: 222 QGPPPQGDNKSQSARSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 279
Query: 1157 GVPPARPPPLTKVPRRAHTLEREVPGIEE--LLVSGRHPSMPAFPALLPAAPGHRGHETC 1214
P PPP R+ R PG + G P P P P P +G
Sbjct: 280 PGKPQGPPPQGGSKSRS---SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 336
Query: 1215 --PDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPR----TPMALPV 1268
P P + GP P GS S PP + +G P+ P P
Sbjct: 337 QGPPPPGKPQGPPPQ--------------GGSKSRSARSPPGKPQGPPQQEGNNPQGPPP 382
Query: 1269 DRKRSQEPSRPSPTPQGPPFGGSRTP 1294
P +P P G P G R P
Sbjct: 383 PA--GGNPQQPQAPPAGQPQGPPRPP 406
Score = 50.1 bits (118), Expect = 1e-05
Identities = 80/292 (27%), Positives = 95/292 (32%), Gaps = 49/292 (16%)
Query: 990 SSRARPRPGGPAPGPNTGLGQVQGQLA--GMYQGADTFMQQLLNRVDGKELPSKSWREPK 1047
S +R PG P P G Q QG G QG Q N+ G P K +
Sbjct: 170 SRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP---QGGNKPQGPPPPGKP--QGP 224
Query: 1048 PEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPV 1107
P GD + S+ P P G P QG PPGKP P + P P
Sbjct: 225 PPQGDNKSQSARSPPGKPQGPPPQGGNQP-QGPPPPPGKPQGPPPQGGNKPQ----GPPP 279
Query: 1108 PTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLT 1167
P G PPP G S + S P KP P G P PPP
Sbjct: 280 P----------------GKPQGPPPQ-GGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP 322
Query: 1168 KVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCEDPGPTPP 1227
P+ P + P P P P G + + P + G PP
Sbjct: 323 GKPQGPPPQGGNKP---------QGPPPPGKPQGPPPQGGSKS-RSARSPPGKPQG--PP 370
Query: 1228 VQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRP 1279
Q N P A G+ P P Q +G PR P + PSRP
Sbjct: 371 QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP--------QGGRPSRP 414
Score = 43.9 bits (102), Expect = 0.001
Identities = 61/246 (24%), Positives = 74/246 (30%), Gaps = 60/246 (24%)
Query: 1078 QGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGS- 1136
QG PPGKP P + P P P G PPP G+
Sbjct: 48 QGPPSPPGKPQGPPPQGGNQPQ----GPPPP---------------PGKPQGPPPQGGNK 88
Query: 1137 -SGTPSKNLPKTKPPRLD------PPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVS 1189
G P P+ PP+ D PPG P PP
Sbjct: 89 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ-----------------------G 125
Query: 1190 GRHPSMPAFPALLPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPL 1249
G P P P P P +G P P P P N +R++ S
Sbjct: 126 GNQPQGPPPPPGKPQGPPPQGGNK-PQGPPPPGKPQGPPPQGDN----KSRSSRSPPGKP 180
Query: 1250 MCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGG---SRTPSTSDMAEEGRVA 1306
PP Q P+ P P K P + PQGPP G P + ++ R
Sbjct: 181 QGPPPQGGNQPQGPP--PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238
Query: 1307 SGGPPG 1312
G P G
Sbjct: 239 PGKPQG 244
Score = 33.1 bits (74), Expect = 1.8
Identities = 41/166 (24%), Positives = 54/166 (32%), Gaps = 16/166 (9%)
Query: 1131 PPDHGSS--GTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLV 1188
PP G+ G PS P KP P G P PPP P+ P
Sbjct: 40 PPQGGNKPQGPPS---PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 96
Query: 1189 SGRHPSMPAFPALLPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDP 1248
+ P + P +P + P + GP PP + P + P
Sbjct: 97 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG---PPPQGGNKPQGP 153
Query: 1249 LMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTP 1294
PP + +G P P +S+ P PQGPP G P
Sbjct: 154 --PPPGKPQGPP------PQGDNKSRSSRSPPGKPQGPPPQGGNQP 191
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 76.6 bits (187), Expect = 1e-13
Identities = 302/1222 (24%), Positives = 377/1222 (30%), Gaps = 240/1222 (19%)
Query: 164 PGGPGPPAAP-PPALDAL-SPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGS 221
PG PGPP P PP L F + A + E+ L P GP
Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFD-----EKAGGAQLGVMQGP-----MGPMG 207
Query: 222 PEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPP 281
P GPP P +P GP G G GE P GP RGPP
Sbjct: 208 PR-------GPPGPAGAP-------GPQGFQG-------NPGEPGEPGVSGPMGP-RGPP 245
Query: 282 QAQGTSSGPNCAPGSSSSSSSDEAGDPNEA-----PSPDTLLGALARRQLNLGQLLEDTE 336
GP PG EAG P +A P P G L G
Sbjct: 246 -------GPPGKPGDDG-----EAGKPGKAGERGPPGPQGARGFPGTPGLP-GVKGHRGY 292
Query: 337 SYLQAFLAGAAGP-LNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGA 395
L A P + G+ PG++ SP P +GLP G T A G
Sbjct: 293 PGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP-----RGLPGER--GRTGPAGAAGARG 345
Query: 396 TSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARG 455
GP P+G G P +PG A+G P+ ARG
Sbjct: 346 NDGQPGP--------AGPPGPVGPAGGPGF------------PGAPG-AKGEAGPTGARG 384
Query: 456 LKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGG--GELSP 513
+ + P +P GP + P IP GS G+P + G G G P
Sbjct: 385 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIP-GAKGSAGAPG-IAGAPGFPGPRGPPGP 442
Query: 514 EGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGP--VVSPCYENILDLSRSTFRGPS 571
+GA G P P P + Q GP P E +R G
Sbjct: 443 QGATG-PLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 501
Query: 572 PEPPPSPLQVP---TYP-QLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAG 627
P PP P +P Q L P+ R P P P G P E L A
Sbjct: 502 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP-GRPGEPGLPGAR 560
Query: 628 SESPHPGRRTP-GNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSE-KNG 685
+ PG P G + G RPG PG R + +G GP+GA G K G
Sbjct: 561 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG--FPGPKGANGEPGKAG 618
Query: 686 VPARPGTEKTRG-PGKSGESAGDMVPSIHRPLEQLEAKG--------GIRGAVALGTNSL 736
PG RG PGK GE+ P P + +G G+ G
Sbjct: 619 EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 678
Query: 737 KQQE---------PGLMGDPGARVYSSH--SMGARVDLEPVS-PRSCLTKVELAKSRLAG 784
K + PGL+G G R + S GA+ P P + T S AG
Sbjct: 679 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 738
Query: 785 ALCPQVPRTPAKVP--TSAPSLGKP--------NKSPHSSPTKLPSKSPTKVVPRPGAPL 834
Q P +P A + P K P +P K + T + PG
Sbjct: 739 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG--- 795
Query: 835 VTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLA-PHSAIEEKVMKGIEE 893
+KG+ P GS A+ P G T P GP G A P A + KG E+
Sbjct: 796 --PAGANGEKGEVGPPGPAGSAGARGAPGERGETGP-PGPAGFAGPPGADGQPGAKG-EQ 851
Query: 894 NVLRLQGQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGAGG-GSPLRR 952
+G APG + S P T T K G G P
Sbjct: 852 GEAGQKGDAGAPGPQ---------------GPSGAPGPQGPTGVTGPKGARGAQGPPGAT 896
Query: 953 EVKMEARKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPN--TGLGQ 1010
A ++ N P P GP PGP+ G
Sbjct: 897 GFPGAAGRVGPPGSN-------------------------GNPGPPGP-PGPSGKDGPKG 930
Query: 1011 VQGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSD-PKSPWPACGP 1069
+G + + +Q G P EP GD P ++ P P G
Sbjct: 931 ARGDSGPPGRAGEPGLQ-------GPAGPPGEKGEP----GDDGPSGAEGPPGPQGLAGQ 979
Query: 1070 RN--GLVGPLQGCGKP--PGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSG 1125
R GL G G P PG PS EPG++ + P P G G
Sbjct: 980 RGIVGLPGQRGERGFPGLPG-PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG 1038
Query: 1126 I-GTFPPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIE 1184
G PP + + +T PG PP P P ++ E G
Sbjct: 1039 SPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG-PPGSPGPAGPTGKQGDRGEAGAQG-- 1095
Query: 1185 ELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCED--------------PGPTPPVQL 1230
PS PA + G RG + +P E PGP
Sbjct: 1096 -----PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGP------ 1144
Query: 1231 AKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGG 1290
G S D P G PR P PV ++ + P P GPP
Sbjct: 1145 -----------PGPSGDQGASGPAGPSG-PRGPPG-PVG-PSGKDGANGIPGPIGPPGPR 1190
Query: 1291 SRTPSTSDMAEEGRVASGGPPG 1312
R+ T G GPPG
Sbjct: 1191 GRSGETGPAGPPGNPGPPGPPG 1212
Score = 41.2 bits (95), Expect = 0.007
Identities = 171/729 (23%), Positives = 219/729 (30%), Gaps = 131/729 (17%)
Query: 614 PYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKT 673
P G P + AG + P R G +G PG PG+
Sbjct: 118 PKGPPGPQG--PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN--------------P 161
Query: 674 GPEGALGSEKNGVPARPGTEKTRGPGKSGESAGD-MVPSIHRPLEQLEAKGGIRGAVALG 732
GP G G G P G + G E AG + + P+ + +G A A G
Sbjct: 162 GPPGPPGPP--GPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 219
Query: 733 TNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPR 792
Q PG G+PG S MG R P P E K AG P P+
Sbjct: 220 PQGF-QGNPGEPGEPGV----SGPMGPRG--PPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272
Query: 793 TPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGP---- 848
P + G P H L GAP V ES P + P
Sbjct: 273 GARGFPGTP---GLPGVKGHRGYPGLDGAK-----GEAGAPGVKGESGSPGENGSPGPMG 324
Query: 849 ---------PWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQ 899
G+ A+ PGP P GP G A E +
Sbjct: 325 PRGLPGERGRTGPAGAAGARGNDGQPGPAGP-PGPVGPAGGPGFPGAPGAKGEAGPTGAR 383
Query: 900 GQERAPGAEVKHRNTSSIASWFGLKKSKLPA---LNRRTEATKNKEGAGGGSPLRREVKM 956
G E A G + G S PA N T+ +G+ G +
Sbjct: 384 GPEGAQGPRGEP----------GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 433
Query: 957 EA-RKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGGP--APGP--NTGLGQV 1011
R L K + + K + P P GP APGP G
Sbjct: 434 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 493
Query: 1012 QGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRN 1071
+G+ G+ G P P Q + PK GP +
Sbjct: 494 RGEPGGV----------------GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGP-S 536
Query: 1072 GLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPP 1131
GL GP +G PG+P EPG +P A G R D+G P
Sbjct: 537 GLAGP-KGANGDPGRP-GEPG----LPG--------------ARGLTGRPGDAG----PQ 572
Query: 1132 PDHGSSGTPSKNLPKTKPPRLDPPPGVPPAR--PPPLTKVPRRAHTLEREVPGIEELL-V 1188
G SG P ++ + PP G P P P E+ +PG L +
Sbjct: 573 GKVGPSGAPGED-GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 631
Query: 1189 SGRHPSMPAFPALLPAAP-GHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSD 1247
G+ A PA P G RG + P P PP + + G +
Sbjct: 632 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691
Query: 1248 PLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQG--PPFGGSRTPSTSDMAEEGRV 1305
P + PR G P R SP QG P G TP T +G
Sbjct: 692 PGLVGPRGERGFP---------------GERGSPGAQGLQGPRGLPGTPGTD--GPKGAS 734
Query: 1306 ASGGPPGLE 1314
GPPG +
Sbjct: 735 GPAGPPGAQ 743
Score = 33.9 bits (76), Expect = 1.1
Identities = 69/298 (23%), Positives = 92/298 (30%), Gaps = 60/298 (20%)
Query: 125 PPSEP--PASPSLSSTEGPAAPL-PLGHCAGQREVCWEQQLRPGGPGPPAAP-PPALDAL 180
P EP +P S GP P+ P G E PG G P A PP D
Sbjct: 1000 PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE--------PGREGSPGADGPPGRDGA 1051
Query: 181 SPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPPQPEPSPW 240
+ + + V +P P P GP P G+ + E
Sbjct: 1052 AGVKGDRGETGAV------------GAPGAPGPPGSPGPAGPTGKQGD-----RGEAGAQ 1094
Query: 241 APCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPS----RGPPQAQGTSSGPNCAPGS 296
P +GP G + G G + + G P RG QG GP PG
Sbjct: 1095 GP---MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLP-GP---PGP 1147
Query: 297 SSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPG 356
S + P+ P +G + N G GP+ PG
Sbjct: 1148 SGDQGASGPAGPSGPRGPPGPVGPSGKDGAN-----------------GIPGPIGP--PG 1188
Query: 357 P-GQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAG 413
P G+S A P + P G G + G G +G PL ++ AG
Sbjct: 1189 PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAG 1246
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 76.6 bits (187), Expect = 1e-13
Identities = 302/1222 (24%), Positives = 377/1222 (30%), Gaps = 240/1222 (19%)
Query: 164 PGGPGPPAAP-PPALDAL-SPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGS 221
PG PGPP P PP L F + A + E+ L P GP
Sbjct: 89 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFD-----EKAGGAQLGVMQGP-----MGPMG 138
Query: 222 PEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPP 281
P GPP P +P GP G G GE P GP RGPP
Sbjct: 139 PR-------GPPGPAGAP-------GPQGFQG-------NPGEPGEPGVSGPMGP-RGPP 176
Query: 282 QAQGTSSGPNCAPGSSSSSSSDEAGDPNEA-----PSPDTLLGALARRQLNLGQLLEDTE 336
GP PG EAG P +A P P G L G
Sbjct: 177 -------GPPGKPGDDG-----EAGKPGKAGERGPPGPQGARGFPGTPGLP-GVKGHRGY 223
Query: 337 SYLQAFLAGAAGP-LNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGA 395
L A P + G+ PG++ SP P +GLP G T A G
Sbjct: 224 PGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP-----RGLPGER--GRTGPAGAAGARG 276
Query: 396 TSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARG 455
GP P+G G P +PG A+G P+ ARG
Sbjct: 277 NDGQPGP--------AGPPGPVGPAGGPGF------------PGAPG-AKGEAGPTGARG 315
Query: 456 LKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGG--GELSP 513
+ + P +P GP + P IP GS G+P + G G G P
Sbjct: 316 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIP-GAKGSAGAPG-IAGAPGFPGPRGPPGP 373
Query: 514 EGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGP--VVSPCYENILDLSRSTFRGPS 571
+GA G P P P + Q GP P E +R G
Sbjct: 374 QGATG-PLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 432
Query: 572 PEPPPSPLQVP---TYP-QLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAG 627
P PP P +P Q L P+ R P P P G P E L A
Sbjct: 433 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP-GRPGEPGLPGAR 491
Query: 628 SESPHPGRRTP-GNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSE-KNG 685
+ PG P G + G RPG PG R + +G GP+GA G K G
Sbjct: 492 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG--FPGPKGANGEPGKAG 549
Query: 686 VPARPGTEKTRG-PGKSGESAGDMVPSIHRPLEQLEAKG--------GIRGAVALGTNSL 736
PG RG PGK GE+ P P + +G G+ G
Sbjct: 550 EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 609
Query: 737 KQQE---------PGLMGDPGARVYSSH--SMGARVDLEPVS-PRSCLTKVELAKSRLAG 784
K + PGL+G G R + S GA+ P P + T S AG
Sbjct: 610 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 669
Query: 785 ALCPQVPRTPAKVP--TSAPSLGKP--------NKSPHSSPTKLPSKSPTKVVPRPGAPL 834
Q P +P A + P K P +P K + T + PG
Sbjct: 670 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG--- 726
Query: 835 VTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLA-PHSAIEEKVMKGIEE 893
+KG+ P GS A+ P G T P GP G A P A + KG E+
Sbjct: 727 --PAGANGEKGEVGPPGPAGSAGARGAPGERGETGP-PGPAGFAGPPGADGQPGAKG-EQ 782
Query: 894 NVLRLQGQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGAGG-GSPLRR 952
+G APG + S P T T K G G P
Sbjct: 783 GEAGQKGDAGAPGPQ---------------GPSGAPGPQGPTGVTGPKGARGAQGPPGAT 827
Query: 953 EVKMEARKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPN--TGLGQ 1010
A ++ N P P GP PGP+ G
Sbjct: 828 GFPGAAGRVGPPGSN-------------------------GNPGPPGP-PGPSGKDGPKG 861
Query: 1011 VQGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSD-PKSPWPACGP 1069
+G + + +Q G P EP GD P ++ P P G
Sbjct: 862 ARGDSGPPGRAGEPGLQ-------GPAGPPGEKGEP----GDDGPSGAEGPPGPQGLAGQ 910
Query: 1070 RN--GLVGPLQGCGKP--PGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSG 1125
R GL G G P PG PS EPG++ + P P G G
Sbjct: 911 RGIVGLPGQRGERGFPGLPG-PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG 969
Query: 1126 I-GTFPPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIE 1184
G PP + + +T PG PP P P ++ E G
Sbjct: 970 SPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG-PPGSPGPAGPTGKQGDRGEAGAQG-- 1026
Query: 1185 ELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCED--------------PGPTPPVQL 1230
PS PA + G RG + +P E PGP
Sbjct: 1027 -----PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGP------ 1075
Query: 1231 AKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGG 1290
G S D P G PR P PV ++ + P P GPP
Sbjct: 1076 -----------PGPSGDQGASGPAGPSG-PRGPPG-PVG-PSGKDGANGIPGPIGPPGPR 1121
Query: 1291 SRTPSTSDMAEEGRVASGGPPG 1312
R+ T G GPPG
Sbjct: 1122 GRSGETGPAGPPGNPGPPGPPG 1143
Score = 41.2 bits (95), Expect = 0.007
Identities = 171/729 (23%), Positives = 219/729 (30%), Gaps = 131/729 (17%)
Query: 614 PYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKT 673
P G P + AG + P R G +G PG PG+
Sbjct: 49 PKGPPGPQG--PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN--------------P 92
Query: 674 GPEGALGSEKNGVPARPGTEKTRGPGKSGESAGD-MVPSIHRPLEQLEAKGGIRGAVALG 732
GP G G G P G + G E AG + + P+ + +G A A G
Sbjct: 93 GPPGPPGPP--GPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150
Query: 733 TNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPR 792
Q PG G+PG S MG R P P E K AG P P+
Sbjct: 151 PQGF-QGNPGEPGEPGV----SGPMGPRG--PPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203
Query: 793 TPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGP---- 848
P + G P H L GAP V ES P + P
Sbjct: 204 GARGFPGTP---GLPGVKGHRGYPGLDGAK-----GEAGAPGVKGESGSPGENGSPGPMG 255
Query: 849 ---------PWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQ 899
G+ A+ PGP P GP G A E +
Sbjct: 256 PRGLPGERGRTGPAGAAGARGNDGQPGPAGP-PGPVGPAGGPGFPGAPGAKGEAGPTGAR 314
Query: 900 GQERAPGAEVKHRNTSSIASWFGLKKSKLPA---LNRRTEATKNKEGAGGGSPLRREVKM 956
G E A G + G S PA N T+ +G+ G +
Sbjct: 315 GPEGAQGPRGEP----------GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364
Query: 957 EA-RKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGGP--APGP--NTGLGQV 1011
R L K + + K + P P GP APGP G
Sbjct: 365 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 424
Query: 1012 QGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRN 1071
+G+ G+ G P P Q + PK GP +
Sbjct: 425 RGEPGGV----------------GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGP-S 467
Query: 1072 GLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPP 1131
GL GP +G PG+P EPG +P A G R D+G P
Sbjct: 468 GLAGP-KGANGDPGRP-GEPG----LPG--------------ARGLTGRPGDAG----PQ 503
Query: 1132 PDHGSSGTPSKNLPKTKPPRLDPPPGVPPAR--PPPLTKVPRRAHTLEREVPGIEELL-V 1188
G SG P ++ + PP G P P P E+ +PG L +
Sbjct: 504 GKVGPSGAPGED-GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 562
Query: 1189 SGRHPSMPAFPALLPAAP-GHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSD 1247
G+ A PA P G RG + P P PP + + G +
Sbjct: 563 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622
Query: 1248 PLMCPPRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQG--PPFGGSRTPSTSDMAEEGRV 1305
P + PR G P R SP QG P G TP T +G
Sbjct: 623 PGLVGPRGERGFP---------------GERGSPGAQGLQGPRGLPGTPGTD--GPKGAS 665
Query: 1306 ASGGPPGLE 1314
GPPG +
Sbjct: 666 GPAGPPGAQ 674
Score = 33.9 bits (76), Expect = 1.1
Identities = 69/298 (23%), Positives = 92/298 (30%), Gaps = 60/298 (20%)
Query: 125 PPSEP--PASPSLSSTEGPAAPL-PLGHCAGQREVCWEQQLRPGGPGPPAAP-PPALDAL 180
P EP +P S GP P+ P G E PG G P A PP D
Sbjct: 931 PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE--------PGREGSPGADGPPGRDGA 982
Query: 181 SPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCGPPQPEPSPW 240
+ + + V +P P P GP P G+ + E
Sbjct: 983 AGVKGDRGETGAV------------GAPGAPGPPGSPGPAGPTGKQGD-----RGEAGAQ 1025
Query: 241 APCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPS----RGPPQAQGTSSGPNCAPGS 296
P +GP G + G G + + G P RG QG GP PG
Sbjct: 1026 GP---MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLP-GP---PGP 1078
Query: 297 SSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPG 356
S + P+ P +G + N G GP+ PG
Sbjct: 1079 SGDQGASGPAGPSGPRGPPGPVGPSGKDGAN-----------------GIPGPIGP--PG 1119
Query: 357 P-GQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAG 413
P G+S A P + P G G + G G +G PL ++ AG
Sbjct: 1120 PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAG 1177
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 76.3 bits (186), Expect = 2e-13
Identities = 187/795 (23%), Positives = 266/795 (33%), Gaps = 166/795 (20%)
Query: 119 PLTPLQPPSEPPASPSLSST-------EGPAAPLPLG-HCAGQREVCWEQQLRPGGPGPP 170
PL+P PP E P SP ++ E PA+PLP H + E E L P P
Sbjct: 448 PLSP--PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLE---ESPLSPPPEESP 502
Query: 171 AAPPPALDALSPFLRK---------KAQILEV-LRALEETDPL---LLCSPATPWRPPGQ 217
+PPP SP + LE L E PL SP +P PP +
Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSP--PPEE 560
Query: 218 GPGSPEPINGELCGPPQ-------PEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDT 270
P SP P L PP+ PE SP +P P L EE
Sbjct: 561 LPTSPPPEASRLSPPPEESPMSPPPEESPMSP-----PPEASRLFP--------PFEE-- 605
Query: 271 GRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAP-SPDTLLGALARRQLNLG 329
P PP+ S P + S S + P E+P SP + L+ + +
Sbjct: 606 ----SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV-VS 660
Query: 330 QLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAH 389
+L E + + P P +S PP+ S + P+ + PE
Sbjct: 661 RLSPPPEE------SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDS 714
Query: 390 RPGFGATSEGQGPLPFLSMFMGAGDAP-LGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPL 448
PLP + P L RP PH S + + P +A+ P
Sbjct: 715 LMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE-----PHLSPQAEEPH 769
Query: 449 LPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSP---SPLLARRG 505
L +P SP GP LSPQ P + + SP P L+ +
Sbjct: 770 LSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQ-PEELHLSPQTEEPHLSPVPEEPCLSPQ- 827
Query: 506 LGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRS 565
PE + P S PC + RP +S LS L P+
Sbjct: 828 -------PEESHLSPQSEEPCLSP------RPEESHLSPELEKPPL-------------- 860
Query: 566 TFRGPSPEPP-------PSPLQVPTYP---QLTLEVPQAPEVLRSPGVPPSPCLPESYPY 615
P PE P P+P ++P +P + +L L PG PP LPE P
Sbjct: 861 ---SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPL 917
Query: 616 GSPQEKSLD-KAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALG-KLKT 673
E SL + P P +P ++ P P +PL + G K +
Sbjct: 918 SPSGEPSLSPQLMPPDPLPPPLSPIITAAAP----------PALSPLGELEYPFGAKGDS 967
Query: 674 GPEGALGSEKNGVPARPGTEKTRG----------PGKSGESAGDMVPSIHRPLEQLEAKG 723
PE L + P P E P G G P + PL
Sbjct: 968 DPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPP----- 1022
Query: 724 GIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSCLTKV-------E 776
+ + L + + Q P P A S S P+SP + V E
Sbjct: 1023 --QCSPLLQHSLVPQNSPPSQCSPPALPLSVPS--------PLSPIGKVVGVSDEAELHE 1072
Query: 777 LAKSRLAGALCPQV-PRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLV 835
+ +++ CP + P + +P+ L P +P+ P+ + APL
Sbjct: 1073 METEKVSEPECPALEPSATSPLPSPMGDLSCP------APSPAPALDDFSGLGEDTAPLD 1126
Query: 836 TKESP--KPDKGKGP 848
++P +P+ G+ P
Sbjct: 1127 GIDAPGSQPEPGQTP 1141
Score = 73.6 bits (179), Expect = 1e-12
Identities = 216/915 (23%), Positives = 305/915 (33%), Gaps = 167/915 (18%)
Query: 121 TPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDAL 180
TP+ PP P + T+ P A C GQ + ++P PGP
Sbjct: 366 TPVCSRFSPP-EPGDTPTDEPDALYVA--CQGQPKGGHVTSMQPKEPGPLQCEA------ 416
Query: 181 SPFLRKKAQILEVLRA-LEETDPLLLCSPATPWR-PPGQGPGSPEPINGELCGPPQPEPS 238
P + Q+ L A L E PLL +P PP + P SP P L PP+ P+
Sbjct: 417 KPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPA 476
Query: 239 PWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSS 298
P LH R L EE P PP+ S P +P S
Sbjct: 477 SPLP----------EALHLSRPL-----EE------SPLSPPPEESPLSPPPESSPFSPL 515
Query: 299 SSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPG 358
S P E+P L +T + + P P
Sbjct: 516 EES--PLSPPEESPPSPAL----------------ETPLSPPPEASPLSPPFEESPLSPP 557
Query: 359 QSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLS-MFMGAGDAPL 417
P PP+ S+ P+ + PE P P S +F ++PL
Sbjct: 558 PEELPTSPPPEASRLSPPPEESPMSPPPE---------ESPMSPPPEASRLFPPFEESPL 608
Query: 418 GSRP-----GHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPG 472
P P +S++ + P SP + P+ P P + LP S SP P
Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS-RLSPLPVVSRLSPPPE 667
Query: 473 GPQLSP--------QLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPS 524
LSP P SR+ S SP P + LP S
Sbjct: 668 ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP----EDSPASPPPEDSLMSLPLEES 723
Query: 525 PCYTTPDSTQLRPPQSALSTTLSP-GPVVSPCYE--NILDLSRSTFRGPSPEPPPSPLQV 581
P P+ QL P + P P +SP E ++ + P PE P V
Sbjct: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPE-EPCLCAV 782
Query: 582 PTYPQLTLEV------PQAPEVLRSP--------GVPPSPCLPESYPYGSPQEKSLDKAG 627
P P L+ + PQ E+ SP VP PCL P+E L
Sbjct: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSP-----QPEESHLSPQS 837
Query: 628 SE---SPHPGRRTPGNSSKKP--SQGSGRRPGDPGSTPLRDRLAAL---GKLKTGP---E 676
E SP P +KP S + P +PG P + L G+ P E
Sbjct: 838 EEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897
Query: 677 GALGSEKNGVPARPGTEK-TRGPGKSGESAGDMVP--SIHRPLEQLEAKGGIRGAVALGT 733
AL SE P P E+ P + ++P + PL + I A
Sbjct: 898 PAL-SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPI-----ITAAAPPAL 951
Query: 734 NSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSC-LTKVELAKSRLAGALCPQ--- 789
+ L + E + GA+ D +P SP + + + ++ A P+
Sbjct: 952 SPLGELE--------------YPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVP 997
Query: 790 ---VPRTP-AKVPTSAPSLGK---PNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKP 842
+P +P + V ++P L + P SP + +P SP P PL + SP
Sbjct: 998 PMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPL-SVPSPLS 1056
Query: 843 DKGKGPPWADCGSTTAQST---------PLVPGPTDPSQGPEG----LAPHSAIEEKVMK 889
GK +D T L P T P P G AP A
Sbjct: 1057 PIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116
Query: 890 GIEENVLRLQGQERAPGAEVKHRNT-SSIASWFG-----LKKSKLPALNRRTEATKNKEG 943
G+ E+ L G + APG++ + T S+AS L +L + + K+
Sbjct: 1117 GLGEDTAPLDGID-APGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQT 1175
Query: 944 AGGGSPLRREVKMEA 958
AG GSP + + A
Sbjct: 1176 AGQGSPCEEQEEPRA 1190
Score = 73.6 bits (179), Expect = 1e-12
Identities = 171/665 (25%), Positives = 228/665 (34%), Gaps = 98/665 (14%)
Query: 119 PLTPLQPPSEPPASPSLSST-------EGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPA 171
P++P PP E P SP ++ E P +P P +L P P
Sbjct: 580 PMSP--PPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA--SRLSPPPEDSPM 635
Query: 172 APPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGELCG 231
+PPP +SP + L L + P SP +P PP + P SP P L
Sbjct: 636 SPPPEESPMSP--PPEVSRLSPLPVVSRLSPPPEESPLSP--PPEESPTSPPPEASRL-- 689
Query: 232 PPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPN 291
P PE SP +P P + E L L EE P P PQ S GP+
Sbjct: 690 SPPPEDSPTSP----PPEDSPASPPPEDSLMSLPLEES---PLLPLPEEPQLCPRSEGPH 742
Query: 292 CAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLN 351
+P S +P+ +P + + + L + E+ QA
Sbjct: 743 LSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA---------E 793
Query: 352 GDHPGPGQSS---SPDQAPPQLSKSKG----LPKSAWGGGTPEAHRPGFGATSEGQGPLP 404
G H P SP P LS P+ +P++ P E P
Sbjct: 794 GPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSP 853
Query: 405 FLSMFMGAGDAPLGSRPGHP---HSSSQVKSKLQIGPPSPGEAQGPLLPSPARG----LK 457
L PL RP P +L + PP + PLL PA
Sbjct: 854 ELE------KPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP 907
Query: 458 FLKLPPTSEKSPSPGGPQLSPQLPRNSRI-----PCRNSGSDGSPSPLLARRGLGGGELS 512
LP SPS G P LSPQL + P + + + SPL GEL
Sbjct: 908 LSPLPEELPLSPS-GEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPL--------GELE 958
Query: 513 -PEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPS 571
P GA+G SP T + PP A T P P + IL S + GP+
Sbjct: 959 YPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM------ILPPSPGSPVGPA 1012
Query: 572 PEPPPSPLQVPTYPQLTLE-VPQ--APEVLRSPGVP---PSPCLPESYPYGSPQEKSLDK 625
PL P L VPQ P P +P PSP P G E L +
Sbjct: 1013 SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHE 1072
Query: 626 AGSE---SPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSE 682
+E P P +S PS P P D + LG+ T P
Sbjct: 1073 METEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGE-DTAP------- 1124
Query: 683 KNGVPARPGTEKTRG--PGK-SGESAGDMV---PSIHRPLEQLEAKGGIRGAVALGTNSL 736
+G+ A PG++ G PG + E G V P P+ +E + G+
Sbjct: 1125 LDGIDA-PGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCE 1183
Query: 737 KQQEP 741
+Q+EP
Sbjct: 1184 EQEEP 1188
Score = 70.5 bits (171), Expect = 1e-11
Identities = 281/1186 (23%), Positives = 382/1186 (32%), Gaps = 236/1186 (19%)
Query: 117 QIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGG---PGP---- 169
+IP P S PPA+ P P L A + L+P PGP
Sbjct: 2105 RIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSA-------DGFLKPPAGSVPGPDSPG 2157
Query: 170 ------PAAPPPALDALSPFLRKKAQILEV-LRALEETDPLLLCSPATPWRPPGQG---- 218
P P + + PF A LE T P P +PP G
Sbjct: 2158 ELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSR 2217
Query: 219 PGSPEPINGELCGPPQPEPSPWAPCLLLGPG--NLGGLLHWERLLGGLGGEEDTGRPWGP 276
PG+ +P P P P P L P +L L E G+GG G+ P
Sbjct: 2218 PGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPES--PGVGG----GKASEP 2271
Query: 277 SRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPN----EAPSPDTLLGALARRQLNLGQLL 332
PP G S +SS G PN ++PS T LG L +
Sbjct: 2272 LLSPPPF-GESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELK-------- 2322
Query: 333 EDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPG 392
T +A L A + PG G P + PP + + P P+ RPG
Sbjct: 2323 --TPDVFKAPLTPRASQVEPQSPGLGLR--PQEPPPAQALAPSPPSH------PDIFRPG 2372
Query: 393 FGATSEGQGPL---PFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLL 449
Q PL P P S P P S ++ P S +Q PL
Sbjct: 2373 SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFS------RVPASPQSQSSSQSPLT 2426
Query: 450 PSPARGLKFLKLPPTSE-KSPSP-GGPQLSPQLPRNSRIPCRNSGSDGSPSP-------- 499
P P F P T +SP P P PQ SR P P P
Sbjct: 2427 PRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQ----SRDPFAPLHKPPRPQPPEVAFKAG 2482
Query: 500 LLARRGLGGGELS---PEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCY 556
LA LG G P G G + P P+ + P A T SP P
Sbjct: 2483 SLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVR-SPGTGAFVGTPSPMRFTFP-- 2539
Query: 557 ENILDLSRSTFRGPSPEP---PPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESY 613
+ + + P P+P PP + P TL PQ+ + G +
Sbjct: 2540 ---QAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATG--------NFH 2588
Query: 614 PYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKT 673
P GSP S G R P S P G P R + + + +
Sbjct: 2589 PSGSPLGPSSGSTGESYGLSPLRPP--SVLPPPAPDGSLPYLSHGASQRSGITSPVEKRE 2646
Query: 674 GPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHRP-LEQLEAKGGIRGAVALG 732
P +GS PGT+ PG SG S ++ R L +L + I+
Sbjct: 2647 DPGTGMGSSL-ATAELPGTQD---PGMSGLSQTELEKQRQRQRLRELLIRQQIQ------ 2696
Query: 733 TNSLKQQEP------GLMGDPGARVYSSHSMGARVDLEPVSPR-SCLTKVELA------K 779
N+L+Q++ G +G PG S GA EP SP L++ + K
Sbjct: 2697 RNTLRQEKETAAAAAGAVGPPG-------SWGA----EPSSPAFEQLSRGQTPFAGTQDK 2745
Query: 780 SRLAGALCPQVPRTPAKVPTSAPS---LGKPNKSPHSSPTKLPSKSPTKV---------V 827
S L G L P P P S PS L +P P ++P+ + S V
Sbjct: 2746 SSLVG-LPPSKLSGPILGPGSFPSDDRLSRP--PPPATPSSMDVNSRQLVGGSQAFYQRA 2802
Query: 828 PRPGA-PLVTKE-------------------------SPKPDKGKGPPWADCGSTTAQST 861
P PG+ PL ++ +P P+ G+ GS A +
Sbjct: 2803 PYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQA----LGSPLAGIS 2858
Query: 862 PLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQ------ERAPGAEVKHRNTS 915
+PGP +P GP G A + V KG+ GQ P +E HR
Sbjct: 2859 TRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAP 2918
Query: 916 SIASWF---GLKKSK-----LPALNRRTEATKNKEGAGGGSPLR--------------RE 953
GL K P LN T + +G + L
Sbjct: 2919 EGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNP 2978
Query: 954 VKMEARKLEAESLNISKLMAKAEDLRRALE--EEKAYLSSRARPRPGGPAPGPNTGLGQV 1011
+ +EA KL E + D +ALE EE A+L G G L
Sbjct: 2979 LALEAGKLPCEDPELDDDF----DAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETN 3034
Query: 1012 QGQLAGMYQGAD----TFMQQLLNRVDGKELPSKSWR------EPKPEYGDFQPVSSDPK 1061
L + G + + L+ D K++ ++ R E + V P
Sbjct: 3035 DPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGVEPGPL 3094
Query: 1062 SPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLA----EPVPTSHFTACG- 1116
P P P P KP E G R P + ++A EP P ++ G
Sbjct: 3095 GPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGL 3154
Query: 1117 ----SLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPR--LDPPP 1156
S+ + D+ +GT P G + + PP L P P
Sbjct: 3155 KPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSP 3200
Score = 70.1 bits (170), Expect = 1e-11
Identities = 209/886 (23%), Positives = 287/886 (32%), Gaps = 138/886 (15%)
Query: 349 PLNGDHP----------GPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEA--------HR 390
PLN + P P SP PP+ S+ P+ PEA
Sbjct: 433 PLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES 492
Query: 391 PGFGATSEGQ-GPLPFLSMFMGAGDAPLG---SRPGHPHSSSQVKSKLQIGPPSPGEAQG 446
P E P P S F ++PL P P + + + P SP +
Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552
Query: 447 PLLPSPAR-----GLKFLKLPPTSEKSPSPGGPQLSPQLP--RNSRI--PCRNSGSDGSP 497
PL P P + +L P E+SP P+ SP P SR+ P S P
Sbjct: 553 PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP 612
Query: 498 SPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYE 557
LSP P SP P+ + + PP + LSP PVVS
Sbjct: 613 EESPLSPPPEASRLSP------PPEDSPMSPPPEESPMSPPPEV--SRLSPLPVVSRL-- 662
Query: 558 NILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGS 617
SP P SPL P T P+A + P P+ PE P
Sbjct: 663 -------------SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP 709
Query: 618 PQEKSLDKAG-SESPH-PGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGP 675
P E SL ESP P P + RP +P +P R L P
Sbjct: 710 PPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSP-RPEEPHLSPQAEEP 768
Query: 676 EGALGSEKN---GVPARPG-TEKTRGPGKSGESAG-DMVPSIHRP-LEQLEAKGGIRGAV 729
+ E+ VP P + + GP S + + P P L + + +
Sbjct: 769 HLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQP 828
Query: 730 ALGTNSLKQQEPGLMGDPGARVYSSH----SMGARVDLEPVSPRSCLTKVELAKSRLAG- 784
S + +EP L P S + R + P P C EL G
Sbjct: 829 EESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGE 888
Query: 785 -ALCPQVPRTPAKVPTSAPSLGKPNK---SPHSSPTKLPSKSPTKVVPRPGAPLVTKESP 840
+L P + P P P + SP P+ P P +P P +P++T +P
Sbjct: 889 PSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP 948
Query: 841 KPDKGKGP---PWADCGSTTAQS--------TPLVPGP----TDPSQGPEG-LAPHSAIE 884
G P+ G + +S TP+ P P TDP P L P
Sbjct: 949 PALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSP 1008
Query: 885 EKVMKGIEENVLRLQGQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGA 944
I L Q + V + S S PAL + + G
Sbjct: 1009 VGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCS--------PPALPLSVPSPLSPIGK 1060
Query: 945 GGGSPLRREV-KMEARKL---EAESLNISK----------LMAKAEDLRRALEEEKAYLS 990
G E+ +ME K+ E +L S L A AL++ L
Sbjct: 1061 VVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSG-LG 1119
Query: 991 SRARPRPGGPAPGPNTGLGQVQGQLAGMYQGADTFMQQLLNRVDGKEL----PSKSWREP 1046
P G APG GQ G LA +G+ + D +EL P + + E
Sbjct: 1120 EDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLL-------DPEELAPVTPMEVYPEC 1172
Query: 1047 KPEYGDFQPVSSD-----PKSPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSED 1101
K G P P +P P ++ +V + + +S PG SE
Sbjct: 1173 KQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDAS-ASFPG------SEP 1225
Query: 1102 SLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKT 1147
L P P GSL+ L P D GS + +LP+T
Sbjct: 1226 LLGSPDPEGG----GSLSMELGVSTDVSPARDEGSLRLCTDSLPET 1267
Score = 65.9 bits (159), Expect = 3e-10
Identities = 199/869 (22%), Positives = 285/869 (32%), Gaps = 152/869 (17%)
Query: 510 ELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRG 569
E P G G+ P + L PP + LSP P SP S
Sbjct: 415 EAKPLGKAGVQLEPQLEAPLNEEMPLLPPPE--ESPLSPPPEESPTSP---PPEASRLSP 469
Query: 570 PSPEPPPSPLQVPTYPQLTLEV-PQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGS 628
P E P SPL + LE P +P SP PP PES P+ +E L
Sbjct: 470 PPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP----PESSPFSPLEESPLSPPEE 525
Query: 629 ESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVPA 688
P P TP + + S P S P E L +P
Sbjct: 526 SPPSPALETPLSPPPEAS---------PLSPPFE-------------ESPLSPPPEELPT 563
Query: 689 RPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPG 748
P E +R ES P P+ + S +E L P
Sbjct: 564 SPPPEASRLSPPPEESPMSPPPE-ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
Query: 749 ARVYS----SHSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSL 804
A S M + P+SP +++ L+ + L P P + P S P
Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSR--LSPLPVVSRLSPP----PEESPLSPP-- 674
Query: 805 GKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLV 864
P +SP S P + SP P +P T P+ PP S + +PL+
Sbjct: 675 --PEESPTSPPPEASRLSP----PPEDSP--TSPPPEDSPASPPPEDSLMSLPLEESPLL 726
Query: 865 PGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQER--APGAEVKHRNTSSIASWFG 922
P P +P P PH + EE L + +E +P AE H +
Sbjct: 727 PLPEEPQLCPRSEGPHLSPRP------EEPHLSPRPEEPHLSPQAEEPHLSPQP------ 774
Query: 923 LKKSKLPALNRRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNISK---LMAKAEDLR 979
++ L A+ + EG SP E+ + + E + + L + E+
Sbjct: 775 -EEPCLCAVPEEPHLSPQAEGPHL-SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH 832
Query: 980 RALEEEKAYLSSRAR--------------PRPGGPAPGPNTGLGQVQGQLAGMYQGADTF 1025
+ + E+ LS R PRP P P G +L +
Sbjct: 833 LSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEP--GQCPAPEELPLFPPPGEPS 890
Query: 1026 MQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKPPG 1085
+ LL E P + P PE P S +P S P P + L PL
Sbjct: 891 LSPLLGEPALSE-PGEPPLSPLPEELPLSP-SGEP-SLSPQLMPPDPLPPPLSPIITAAA 947
Query: 1086 KPSSEP--------GRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFP-PPDHGS 1136
P+ P G + + E LA P+ + + T + PP GS
Sbjct: 948 PPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007
Query: 1137 SGTPSKNL------------------PKTKPPRLDPPPGVPPARPPPLTKVPR------- 1171
P+ + P+ PP PP +P + P PL+ + +
Sbjct: 1008 PVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDE 1067
Query: 1172 -RAHTLERE---VPGIEELLVSGRHP--------SMPAFPALLPAAPGHR--GHETCPDD 1217
H +E E P L S P S PA P+ PA G +T P D
Sbjct: 1068 AELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPA-PSPAPALDDFSGLGEDTAPLD 1126
Query: 1218 PCEDPGPTP-PVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEP 1276
+ PG P P Q P + A+ P++ P +L P TPM + + K++
Sbjct: 1127 GIDAPGSQPEPGQT------PGSLASELKGSPVLLDPEEL--APVTPMEVYPECKQTAGQ 1178
Query: 1277 SRPSPTPQGPPFGGSRTPST---SDMAEE 1302
P + P + TP T SD+ E
Sbjct: 1179 GSPCEEQEEPRAPVAPTPPTLIKSDIVNE 1207
Score = 50.8 bits (120), Expect = 8e-06
Identities = 73/260 (28%), Positives = 91/260 (35%), Gaps = 51/260 (19%)
Query: 1048 PEYGDFQPVSSDPKSPWPACG--PRNGLV--------GPLQGCGKPPGKPSSEPGRREEM 1097
PE GD + +P + + AC P+ G V GPLQ KP GK G + E
Sbjct: 375 PEPGDTP--TDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKA----GVQLEP 428
Query: 1098 PSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPP---RLDP 1154
E L E +P PPP+ P + P + PP RL P
Sbjct: 429 QLEAPLNEEMPL-------------------LPPPEESPLSPPPEESPTSPPPEASRLSP 469
Query: 1155 PPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETC 1214
PP PA P P R P EE +S S P P L +P E+
Sbjct: 470 PPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSP--LEESPLSPPEESP 527
Query: 1215 PDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQ 1274
P E P PP + F PL PP +L P P A + +
Sbjct: 528 PSPALETPLSPPPEASPLSPPF--------EESPLSPPPEELPTSP-PPEASRLSPPPEE 578
Query: 1275 EPSRPSP--TPQGPPFGGSR 1292
P P P +P PP SR
Sbjct: 579 SPMSPPPEESPMSPPPEASR 598
Score = 50.4 bits (119), Expect = 1e-05
Identities = 127/522 (24%), Positives = 169/522 (32%), Gaps = 116/522 (22%)
Query: 791 PRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPGAPLVTKESP----KPDKGK 846
P ++P +LG P P+ +PT + P P S KP G
Sbjct: 2100 PALHLRIPPQPGALGSPP----------PAAAPTIFIGSPTTPAGLSTSADGFLKPPAGS 2149
Query: 847 GPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMK------------GIEEN 894
P G + P VP PSQ P GLAP +E + G
Sbjct: 2150 VPGPDSPGELFLKLPPQVPAQV-PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQ 2208
Query: 895 VLRLQGQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKN-----KEGAGGGSP 949
L R + +T+ + + P L R + N G GGG
Sbjct: 2209 PPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG-- 2266
Query: 950 LRREVKMEARKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPRPGGPAPGPNTGLG 1009
K L S R+ALE +K L + + P+ GP LG
Sbjct: 2267 -----KASEPLLSPPPFGES---------RKALEVKKEELGASS------PSYGP-PNLG 2305
Query: 1010 QVQGQLAGMYQGA------DTFMQQLLNRVDGKEL-------------PSKSWREPKPEY 1050
V +G + G D F L R E P+++ P +
Sbjct: 2306 FVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSH 2365
Query: 1051 GD-FQPVSSDPKSPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPT 1109
D F+P S P PR P C PP S+P R +P+ P
Sbjct: 2366 PDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSR--VPAS-------PQ 2416
Query: 1110 SHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDP---PPGVPPARPP-- 1164
S ++ LT P P + PS P+ + P DP PP P +R P
Sbjct: 2417 SQSSSQSPLT----------PRPLSAEAFCPSPVTPRFQSP--DPYSRPPSRPQSRDPFA 2464
Query: 1165 PLTKVPRRAHTLEREVPGIEELLVSGRHPSMPA--FPALLPAAPGHRGHETCPDDP---- 1218
PL K PR + P + S H S+ A FPA LPA P H P
Sbjct: 2465 PLHKPPRP------QPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNF 2518
Query: 1219 CEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLP 1260
PG V F +A G +P + PP GLP
Sbjct: 2519 VRSPGTGAFVGTPSPMRFTFPQAVG---EPSLKPPVPQPGLP 2557
Score = 49.7 bits (117), Expect = 2e-05
Identities = 147/607 (24%), Positives = 208/607 (34%), Gaps = 87/607 (14%)
Query: 13 GNPRPGEGDDGSMEPGTCQELLHRLRELEAENSALAQANENQRETYERCLDEVANHVVQA 72
G P+ GS++ Q+ L + ++L+ + Q + ++ ++ Q
Sbjct: 3885 GQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQ------QQLQQQQQQQ 3938
Query: 73 LLNQKDLREECIKLKKRVFDLERQNQMLSALFQQKLQLTTGSLPQIPLTPLQPPSEPPAS 132
L Q+ ++ L+++ L++Q Q FQQ+ Q L T L P +
Sbjct: 3939 QLQQQQQQQ----LQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQ 3994
Query: 133 PSLSSTEGPAAPL-PLGHCAGQREVCWEQQLRPGGPGPPAA-PPPALDALSPFLRKKAQI 190
+L GP P PL H + PG GP + + P + +A
Sbjct: 3995 VAL----GPGMPAKPLQHFSS-----------PGALGPTLLLTGKEQNTVDPAVSSEATE 4039
Query: 191 LEVLRALEETDPLLL-CSPATPWRPPGQGPGSPEPINGELCGPPQPEPSPWAPCLLLGPG 249
+ + PL + +P + PG+ S + L PQP+P P + L P
Sbjct: 4040 GP---STHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQP-SSLQLQPPL 4095
Query: 250 NLGG-------LLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSS-- 300
L G LLH GG G+ +G S P S PGS + +
Sbjct: 4096 RLPGQQQQQVSLLHTAG--GGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLL 4153
Query: 301 -----SSDEAGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGA-AGPLNGDH 354
+ N P P L Q G + T L+A L G A H
Sbjct: 4154 GPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRH 4213
Query: 355 PGPGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPL---PFLSMFMG 411
P Q Q L + L +S TP PG TS QG L P L F G
Sbjct: 4214 LSPQQQ----QQLQALLMQRQLQQSQAVRQTPPYQEPGT-QTSPLQGLLGCQPQLGGFPG 4268
Query: 412 AGDAPL-----GSRPGHPHSSSQVKSKLQIGP--------PSPGEAQGPL----LPSPAR 454
PL G RP P L GP P P Q P LPSP+
Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328
Query: 455 GLKF-LKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSP 513
L +LPPT +P P GP L P P R S + + L +GLG +
Sbjct: 4329 QLPTEAQLPPTHPGTPKPQGPTLEPP-------PGRVSPAAAQLADTLFSKGLGPWDPPD 4381
Query: 514 EGAQGLPTSPS---PCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGP 570
A+ S P + + Q+ P S LS + P PC + R P
Sbjct: 4382 NLAETQKPEQSSLVPGHLDQVNGQVVPEASQLS--IKQEPREEPCALGAQSVKREANGEP 4439
Query: 571 SPEPPPS 577
P S
Sbjct: 4440 IGAPGTS 4446
Score = 44.3 bits (103), Expect = 8e-04
Identities = 180/815 (22%), Positives = 261/815 (32%), Gaps = 188/815 (23%)
Query: 120 LTPLQPPSE-PPASPSLSSTEGPAAPLP-LGHCAGQREVCWEQQLRPGGPGP-------- 169
L+PL+PPS PP +P S LP L H A QR + PG
Sbjct: 2607 LSPLRPPSVLPPPAPDGS--------LPYLSHGASQRSGITSPVEKREDPGTGMGSSLAT 2658
Query: 170 ---PAAPPPALDALSPFLRKKAQILEVLRAL------------EETDPLLLCSPATPWRP 214
P P + LS +K + + LR L +E + + A P
Sbjct: 2659 AELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVG--P 2716
Query: 215 PGQGPGSPEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPW 274
PG P SP L G G L+G L + +G
Sbjct: 2717 PGSWGAEPS--------------SPAFEQLSRGQTPFAGTQDKSSLVG-LPPSKLSGPIL 2761
Query: 275 GPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPN----EAPSPDTLLGALARRQLNLGQ 330
GP P + + P P S +S G AP P +L L ++Q L Q
Sbjct: 2762 GPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSL--PLQQQQQQLWQ 2819
Query: 331 LLEDTESYLQAFLAGA---------------AGPLNGDH---PGPGQSSSPDQAPPQLSK 372
+ T + F A PL G PGPG+ P Q +
Sbjct: 2820 QQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIE 2879
Query: 373 SK-GLPKSAWGGGTP-----EAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHS 426
+ + K GGTP RP F SE L + G A G P P +
Sbjct: 2880 LRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGL---RGLAVSGLPPQKPSA 2936
Query: 427 --SSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNS 484
+ ++ + L P+P +GP LP+ GL+ + PP+S + P +P
Sbjct: 2937 PPAPELNNSLH---PTP-HTKGPTLPT---GLELVNRPPSSTELGRP-----NPLALEAG 2984
Query: 485 RIPCRNSGSDGS--------PSPLLARRGLG----GGELSPEGAQGLPTSPSP------- 525
++PC + D LA GLG G+ + L T+
Sbjct: 2985 KLPCEDPELDDDFDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNG 3044
Query: 526 ------CYTTPD------------------STQLRPPQSALSTTLSPGPVVSPCYENILD 561
YT P+ S + + AL + PGP+
Sbjct: 3045 DEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGVEPGPL---------- 3094
Query: 562 LSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPC-----LPESYPYG 616
GP PPP+ + P+L +P+ + G PSPC P+ P
Sbjct: 3095 -------GPEERPPPAA--DASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAP 3145
Query: 617 SPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPE 676
+ L +S R T + S G G+T +GP
Sbjct: 3146 AANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPG 3205
Query: 677 GALGSEK----NGVPARPGTEKTRGPGKSGESAGDMVPSI---HRPL----------EQL 719
G+ EK +G PG GP SG+ M S+ PL ++L
Sbjct: 3206 GSSLLEKFELESGALTLPG-----GPAASGDELDKMESSLVASELPLLIEDLLEHEKKEL 3260
Query: 720 EAKGGIRGAVALGTNSLKQQEP-GLMGDPG-ARVYSSHSMGARVDLEPVSPRSCLTKVEL 777
+ K + + +QQ+ L+ PG A+ S G+ L + L
Sbjct: 3261 QKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGA 3320
Query: 778 AKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPH 812
+ L L P P A APS+ + H
Sbjct: 3321 RQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGH 3355
Score = 43.9 bits (102), Expect = 0.001
Identities = 80/352 (22%), Positives = 109/352 (30%), Gaps = 105/352 (29%)
Query: 1039 PSKSWREPKPEYGD-FQPVSSDPKSPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREEM 1097
P +S P PE F P P SP P P + + P P S P
Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP------ 638
Query: 1098 PSEDSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPP---RLDP 1154
P E ++ P S + ++R PPP+ P + P + PP RL P
Sbjct: 639 PEESPMSPPPEVSRLSPLPVVSRLS-------PPPEESPLSPPPEESPTSPPPEASRLSP 691
Query: 1155 PPGVPPARPPP----------------------------------------LTKVPRRAH 1174
PP P PPP L+ P H
Sbjct: 692 PPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPH 751
Query: 1175 TLEREV-----PGIEELLVSGRHP-----SMPAFPALLPAAPG----------HRGHET- 1213
R P EE +S + ++P P L P A G H +T
Sbjct: 752 LSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTE 811
Query: 1214 ------CPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCP-PRQLEGLPRT--PM 1264
P++PC P P + + S +P + P P + P P
Sbjct: 812 EPHLSPVPEEPCLSPQPE------------ESHLSPQSEEPCLSPRPEESHLSPELEKPP 859
Query: 1265 ALPVDRKRSQEPSR---PSPTPQGPPFGGSRTPSTSDMAEEGRVASGGPPGL 1313
P K +EP + P P PP G PS S + E ++ G P L
Sbjct: 860 LSPRPEKPPEEPGQCPAPEELPLFPPPG---EPSLSPLLGEPALSEPGEPPL 908
Score = 38.5 bits (88), Expect = 0.044
Identities = 39/143 (27%), Positives = 52/143 (36%), Gaps = 20/143 (13%)
Query: 116 PQIPL------TPLQPPSE---------PPA--SPSLSSTEGPAAPLPLGHCAGQREVCW 158
P+ PL TP+ PP E PP PS S GPA+P+ + Q
Sbjct: 969 PESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLL 1028
Query: 159 EQQLRPGGPGPPAAPPPALDALSPF-LRKKAQILEVL--RALEETDPLLLCSPATPWRPP 215
+ L P P PPAL P L +++ V L E + + P P P
Sbjct: 1029 QHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEP 1088
Query: 216 GQGPGSPEPINGELCGPPQPEPS 238
P P+ C P P P+
Sbjct: 1089 SATSPLPSPMGDLSCPAPSPAPA 1111
Score = 37.4 bits (85), Expect = 0.097
Identities = 182/825 (22%), Positives = 291/825 (35%), Gaps = 161/825 (19%)
Query: 476 LSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSP----EGAQGLPT---SPSPCYT 528
L P +P P ++ S G+ P L G + P E +G T P T
Sbjct: 3997 LGPGMPAK---PLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGT 4053
Query: 529 TPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLT 588
TP+S P + V P ++ S+ P P+P PS LQ+ +L
Sbjct: 4054 TPESMATEPGE------------VKP---SLSGDSQLLLVQPQPQPQPSSLQLQPPLRLP 4098
Query: 589 LEVPQAPEVLRSPGVPP-------SPCLPESYPY--GSPQEKSLDKAGSESPHP-GRRTP 638
+ Q +L + G S S P+ P D+ GS + + G + P
Sbjct: 4099 GQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQP 4158
Query: 639 GNSSKKPSQGS-GRRPGDPGSTPLRDR-LAALGKLKTGPEGALGSEKNGVPARPGTEKTR 696
++P Q + G +P PG + L +G + T G L ++ GV A+ +
Sbjct: 4159 --MLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPT--VGQLRAQLQGVLAKNPQLRHL 4214
Query: 697 GPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQ-----EPGLMGDPGARV 751
P + + ++ R L+Q +A GT + Q +P L G PG +
Sbjct: 4215 SPQQQQQLQALLM---QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQT 4271
Query: 752 YSSHSMGARVDLEPVSPRSCLTKVELAKSRLAGAL-------CPQVPRTPAKVPTSAPSL 804
+GA + PR L+ + G + PQ P+ P+++P+ + L
Sbjct: 4272 GPLQELGAGPRPQG-PPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL 4330
Query: 805 GKPNKSPHSSPTKLPSKSPTKVVPRPG--APLVTKESPKP-DKGKG---PPWADCGSTTA 858
+ P + P + PT + P PG +P + + KG G PP +
Sbjct: 4331 PTEAQLPPTHPGTPKPQGPT-LEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389
Query: 859 QSTPLVPGPTD------------------PSQGPEGLAPHSAIEEKVMKGI----EENVL 896
+ + LVPG D P + P L S E + I N L
Sbjct: 4390 EQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHL 4449
Query: 897 RLQGQERAPG-------AEVKHRNTSSIASWFGLK-------KSKLPALNRRTEAT-KNK 941
L G G K+ S+ GL+ SKL L ++ + T NK
Sbjct: 4450 LLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNK 4509
Query: 942 EGAGGGSPLRREVKMEARKLEAESLNISKLMAKAEDLRRA---LEEEKAYLSSRARPRPG 998
E A PL + K +K ++ K + K + +R + L++ K LS P
Sbjct: 4510 EDAAARKPLTPKPK-RVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPA 4568
Query: 999 GPA----------PGPNTGLGQVQGQL-AGMYQGADTFMQQLLNRVDGKELPSKSWREPK 1047
A P G Q++G +G + QLL + + P+
Sbjct: 4569 ITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPT------- 4621
Query: 1048 PEYGDFQPVSSDPKSPWPACGPR--NGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAE 1105
P SS P +P P+ + NG V P + G+ P +S R E D+
Sbjct: 4622 -------PPSSLPPTPPPSVQQKMVNG-VTPSEELGEHPKDAAS--ARDSERALRDT--- 4668
Query: 1106 PVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPP 1165
S ++LD + P P H ++++ D P + PA P
Sbjct: 4669 -----------SEVKSLDL-LAALPTPPHNQ----TEDVRMESDEDSDSPDSIVPASSPE 4712
Query: 1166 L---TKVPRRAH----TLEREVPGIEELLVSGRHPSMPAFPALLP 1203
+ PR H E+E + ++ S+P FP P
Sbjct: 4713 SILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKP 4757
Score = 34.7 bits (78), Expect = 0.63
Identities = 85/328 (25%), Positives = 109/328 (33%), Gaps = 65/328 (19%)
Query: 162 LRPGGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGS 221
+ PG GP PPPA DA P R + + EV +EE G
Sbjct: 3089 VEPGPLGPEERPPPAADASEP--RLASVLPEVKPKVEE------------------GGRH 3128
Query: 222 PEPINGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGR-----PWGP 276
P P + P+ EP+P A L LG ++ G G +G +G
Sbjct: 3129 PSPCQFTI-ATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGA 3187
Query: 277 SRGPPQAQGTSSGPNCAPGSSSSSSSDE---------AGDPNEAPSPDTLLGALARRQLN 327
+ GPP A + P PG SS E G D + +L +L
Sbjct: 3188 TGGPP-AHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELP 3246
Query: 328 L--GQLLEDTESYLQ--AFLAGAAGPLNGDH-----------PGPGQS-------SSPDQ 365
L LLE + LQ L+ P PGP Q+ SSP
Sbjct: 3247 LLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSL 3306
Query: 366 APPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPL-PFLSMFMGAGDAPLGSRPGH- 423
A Q S GL A G P+ P Q L P ++M G G G
Sbjct: 3307 AGSQQQLSLGL-AGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQA 3365
Query: 424 ---PHSSSQ-VKSKLQIGPPSPGEAQGP 447
P SSQ V S+ +G P P
Sbjct: 3366 GLVPQQSSQPVLSQKPMGTMPPSMCMKP 3393
Score = 34.3 bits (77), Expect = 0.82
Identities = 113/453 (24%), Positives = 148/453 (32%), Gaps = 120/453 (26%)
Query: 100 LSALFQQKLQLTTGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQREVCWE 159
LS L + G P PL P + P P PSLS P PLP
Sbjct: 891 LSPLLGEPALSEPGEPPLSPL-PEELPLSPSGEPSLSPQLMPPDPLP------------- 936
Query: 160 QQLRPGGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDP------LLLCSPATPWR 213
P P AA PPAL L ++ A ++DP +L +P +P
Sbjct: 937 ---PPLSPIITAAAPPALSPL-------GELEYPFGAKGDSDPESPLAAPILETPISP-- 984
Query: 214 PPGQGPGSPEPINGELCGPPQ-PEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGR 272
PP PEP+ PP PSP +P +GP +
Sbjct: 985 PPEANCTDPEPV------PPMILPPSPGSP---VGPAS---------------------- 1013
Query: 273 PWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSP----DTLLGALARRQLNL 328
P PPQ + P +S S P PSP ++G +L+
Sbjct: 1014 PILMEPLPPQCSPLLQ-HSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHE 1072
Query: 329 GQLLEDTESYLQAFLAGAAGPLNGDHPGP-GQSSSPDQAP-PQLSKSKGLPKSA------ 380
+ + +E A A PL P P G S P +P P L GL +
Sbjct: 1073 METEKVSEPECPALEPSATSPL----PSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGI 1128
Query: 381 -WGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPP 439
G PE + SE +G L A P+ P + K G
Sbjct: 1129 DAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYP---------ECKQTAGQG 1179
Query: 440 SPGEAQ----GPLLPSPARGLK---FLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSG 492
SP E Q P+ P+P +K ++ S+ S P P L
Sbjct: 1180 SPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLL------------ 1227
Query: 493 SDGSPSPLLARRGLGGGELSPEGAQGLPTSPSP 525
GSP P GGG LS E G+ T SP
Sbjct: 1228 --GSPDP------EGGGSLSME--LGVSTDVSP 1250
Score = 34.3 bits (77), Expect = 0.82
Identities = 39/149 (26%), Positives = 55/149 (36%), Gaps = 13/149 (8%)
Query: 1177 EREVPGIEELLVSGRHPS-----MPAFPALLPAAPGHRGHETCPDDPCEDPGPTPPVQLA 1231
E E PG +E + G+ P + F A+LP + E P P PP Q +
Sbjct: 4834 EAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHS 4893
Query: 1232 KNWTFPNTRAAGSSSDP---LMCPPRQLEGLPRTPMALPVDRKRSQ---EPSRPSPTPQG 1285
+ N S+ P PP L P +P P+ ++ EP PSP P
Sbjct: 4894 YTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLA 4953
Query: 1286 PPFGGSRTPSTSDMAEEGRVASGGPPGLE 1314
+R + EEG PP L+
Sbjct: 4954 SSPESARPKPRARPPEEGE--DSRPPRLK 4980
Score = 33.5 bits (75), Expect = 1.4
Identities = 54/201 (26%), Positives = 70/201 (34%), Gaps = 62/201 (30%)
Query: 349 PLNGDHPGPG------QSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGP 402
P G+ GPG + SPD P L + +A PG+ S+
Sbjct: 4830 PKKGEAEGPGGKEKGLEGKSPDTGPDWLKQF-------------DAVLPGYTLKSQ---- 4872
Query: 403 LPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKL---QIGPPSPGEAQGPLLPSPARGLKFL 459
L LS+ AP P HS + S L Q+ P P E PSP
Sbjct: 4873 LDILSLLKQESPAP---EPPTQHSYTYNVSNLDVRQLSAPPPEE------PSP------- 4916
Query: 460 KLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPL-LARRGLGGGELSPEGAQG 518
P S +PSP P P + +P PSPL LA SPE A+
Sbjct: 4917 ---PPSPLAPSPASPPTEPLV----ELPTEPLAEPPVPSPLPLAS--------SPESARP 4961
Query: 519 LPTSPSPCYTTPDSTQLRPPQ 539
P + P + RPP+
Sbjct: 4962 KPRARPP----EEGEDSRPPR 4978
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 74.3 bits (181), Expect = 7e-13
Identities = 162/611 (26%), Positives = 204/611 (33%), Gaps = 122/611 (19%)
Query: 307 DPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLA-------GAAGPLN---GDHPG 356
DP + S + +LG LA LL D E GAAGP G P
Sbjct: 1449 DPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPS 1508
Query: 357 PGQSSSPDQAPPQLSKSKGLPKSAWGGGTPEAHRPGFGATSEGQGPLPFLSMFM--GAGD 414
P SP P W G A+ G + S G G P + F A D
Sbjct: 1509 PMGGISPAMTP-------------WNQGATPAY--GAWSPSVGSGMTPGAAGFSPSAASD 1553
Query: 415 APLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSP-SPGG 473
A G PG+ + S P SPG + P +PSP + P + P SPGG
Sbjct: 1554 AS-GFSPGYSPAWSPTPGS----PGSPGPSS-PYIPSPGGAMSPSYSPTSPAYEPRSPGG 1607
Query: 474 PQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDST 533
+PQ P S S + S SP SP PTSPS T+P +
Sbjct: 1608 --YTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1665
Query: 534 QLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPE-PPPSPLQVPTYPQLTLEVP 592
P S S + SP SP Y + ++ SP P SP PT P + P
Sbjct: 1666 PTSPSYSPTSPSYSP---TSPSYSP----TSPSYSPTSPSYSPTSPSYSPTSPSYS---P 1715
Query: 593 QAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKAGSE-SPHPGRRTPGNSSKKPSQGSGR 651
+P P SP + P SP S SP TP + S P+ S
Sbjct: 1716 TSPSYS-----PTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPS-Y 1769
Query: 652 RPGDPGSTPLRDRLAALGKLKTGPEGALGSEKNGVPARPGTEKTRGPGKSGESAGDMVPS 711
P P TP T P N P P T P S S PS
Sbjct: 1770 SPTSPNYTP------------TSP--------NYSPTSPSYSPT-SPSYSPTSPS-YSPS 1807
Query: 712 IHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSSHSMGARVDLEPVSPRSC 771
R Q + + + S P P + YS S + P SP+
Sbjct: 1808 SPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYT--PTSPSYSPSSP----EYTPTSPKYS 1861
Query: 772 LTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPRPG 831
T + + P +P PTS P SPT P SPT P
Sbjct: 1862 PTSPKYS------------PTSPKYSPTS----------PTYSPTT-PKYSPTSPTYSPT 1898
Query: 832 APLVTKESPK---------PDKGKGPPWADCGSTTAQS----TPLVPG--PTDP--SQGP 874
+P+ T SPK P K P + S T+ +P PG PT P S
Sbjct: 1899 SPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTS 1958
Query: 875 EGLAPHSAIEE 885
++P + EE
Sbjct: 1959 PAISPDDSDEE 1969
Score = 64.3 bits (155), Expect = 7e-10
Identities = 112/453 (24%), Positives = 161/453 (35%), Gaps = 74/453 (16%)
Query: 207 SPATPWRPPGQGPGSPEPINGELCGPP---QPEPSPWAPCLLLGPGNLGGLLHWERLLGG 263
SPA W P PGSP P + + P P SP +P + R GG
Sbjct: 1562 SPA--WSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPA------------YEPRSPGG 1607
Query: 264 LGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALAR 323
+ + P PS P + + PN +P S S S + P+ +P+ +
Sbjct: 1608 YTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTS----PSYSPTSPSYSPTSPS 1663
Query: 324 RQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQS-SSPDQAPPQLSKSKGLPKSAWG 382
+ SY + + + P S +SP +P S S P +
Sbjct: 1664 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1723
Query: 383 GGTPEAHRPGFGATSEGQGPL-----PFLSMFMGAGDAPLGSRPGH-PHSSSQVKSKLQI 436
+ P + TS P P + + + P + P S + +
Sbjct: 1724 SPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNY 1783
Query: 437 GPPSPGEAQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGS 496
P SP + P PS + PTS S SP P+ +PQ P + P S S S
Sbjct: 1784 SPTSP--SYSPTSPSYS---------PTSP-SYSPSSPRYTPQSP--TYTPSSPSYSPSS 1829
Query: 497 PSPLLARRGLGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSP-GPVVSPC 555
PS SP + PTSPS ++P+ T P S S SP P SP
Sbjct: 1830 PS------------YSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSP- 1876
Query: 556 YENILDLSRSTFRGPSPE-PPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPP-SPCLPESY 613
+ T+ +P+ P SP PT P T P +P+ SP P SP P+
Sbjct: 1877 -------TSPTYSPTTPKYSPTSPTYSPTSPVYT---PTSPKY--SPTSPTYSPTSPKYS 1924
Query: 614 PYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPS 646
P + K + SP +PG S P+
Sbjct: 1925 PTSPTYSPTSPKGSTYSP----TSPGYSPTSPT 1953
Score = 40.0 bits (92), Expect = 0.015
Identities = 77/325 (23%), Positives = 102/325 (31%), Gaps = 30/325 (9%)
Query: 1016 AGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQPVSSDPKSPW---------PA 1066
+GM GA F + G P P P S P SP+ P+
Sbjct: 1537 SGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPG----SPGSPGPSSPYIPSPGGAMSPS 1592
Query: 1067 CGPRNGLVGPLQGCGKPPGKPSSEPGRREEMPSEDSLAEPVPTSHFTACGSLTRTLDSGI 1126
P + P G P PS P P+ S + P ++ S + T S
Sbjct: 1593 YSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYS-PTSPNYSPTSPSYSPTSPSYS 1651
Query: 1127 GTFPP--PDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIE 1184
T P P S S + T P P P P P + T P
Sbjct: 1652 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1711
Query: 1185 ELLVSGRHPSM-PAFPALLPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAG 1243
S PS P P+ P +P + + PT P + ++ T +
Sbjct: 1712 SY--SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSY 1769
Query: 1244 SSSDPLMCP------PRQLEGLPRTPMALPVDRKRSQEPSRPSPTPQGPPFGGSRTPSTS 1297
S + P P P P +P P S PS P TPQ P + S +PS S
Sbjct: 1770 SPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSP--SYSPSSPRYTPQSPTYTPS-SPSYS 1826
Query: 1298 DMAEEGRVASGGPPGLETSESLSDS 1322
+ S P TS S S S
Sbjct: 1827 PSSPSYSPTS--PKYTPTSPSYSPS 1849
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.132 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,645,001
Number of Sequences: 37866
Number of extensions: 5868828
Number of successful extensions: 52933
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 188
Number of HSP's successfully gapped in prelim test: 2030
Number of HSP's that attempted gapping in prelim test: 27998
Number of HSP's gapped (non-prelim): 19339
length of query: 1334
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1220
effective length of database: 13,930,794
effective search space: 16995568680
effective search space used: 16995568680
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.