Search of human proteins with 113426932

Search of human proteins with 113426932

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|113426932 PREDICTED: similar to N-ethylmaleimide-sensitive
factor [Homo sapiens]
         (563 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|113426932 PREDICTED: similar to N-ethylmaleimide-sensitive fa...  1112   0.0  
gi|156564401 vesicle-fusing ATPase [Homo sapiens]                     961   0.0  
gi|239740963 PREDICTED: similar to N-ethylmaleimide-sensitive fa...   642   0.0  
gi|6005942 valosin-containing protein [Homo sapiens]                  161   2e-39
gi|157671927 spermatogenesis associated 5 [Homo sapiens]              158   1e-38
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]            150   2e-36
gi|4505725 peroxin1 [Homo sapiens]                                    147   2e-35
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                 146   4e-35
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                 146   4e-35
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]            144   3e-34
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]           139   7e-33
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]            135   1e-31
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ...   134   2e-31
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi...   134   2e-31
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]   134   2e-31
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]   134   3e-31
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]     132   8e-31
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]       130   3e-30
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]           130   3e-30
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]             130   3e-30
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]            129   7e-30
gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]              115   8e-26
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]                      114   2e-25
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]                       114   2e-25
gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]          112   9e-25
gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]          112   9e-25
gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo sap...   112   9e-25
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]               106   6e-23
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]               106   6e-23
gi|5901990 katanin p60 subunit A 1 [Homo sapiens]                     100   5e-21

>gi|113426932 PREDICTED: similar to N-ethylmaleimide-sensitive
           factor [Homo sapiens]
          Length = 563

 Score = 1112 bits (2877), Expect = 0.0
 Identities = 563/563 (100%), Positives = 563/563 (100%)

Query: 1   MAPPLCPPRAPQAAAEPARAPCGARTPGTRPGTRASSRRLHACARAGGGGARAAGAGFAE 60
           MAPPLCPPRAPQAAAEPARAPCGARTPGTRPGTRASSRRLHACARAGGGGARAAGAGFAE
Sbjct: 1   MAPPLCPPRAPQAAAEPARAPCGARTPGTRPGTRASSRRLHACARAGGGGARAAGAGFAE 60

Query: 61  RRAAAAEPDVSAKMAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTF 120
           RRAAAAEPDVSAKMAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTF
Sbjct: 61  RRAAAAEPDVSAKMAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTF 120

Query: 121 TLKTHPSVVPGSIAFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSI 180
           TLKTHPSVVPGSIAFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSI
Sbjct: 121 TLKTHPSVVPGSIAFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSI 180

Query: 181 DSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATG 240
           DSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATG
Sbjct: 181 DSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATG 240

Query: 241 KRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEF 300
           KRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEF
Sbjct: 241 KRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEF 300

Query: 301 SDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNG 360
           SDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNG
Sbjct: 301 SDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNG 360

Query: 361 PEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVH 420
           PEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVH
Sbjct: 361 PEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVH 420

Query: 421 DTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQIL 480
           DTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQIL
Sbjct: 421 DTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQIL 480

Query: 481 HIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDM 540
           HIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDM
Sbjct: 481 HIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDM 540

Query: 541 EKAESLQVMRGDFLASLENDIKP 563
           EKAESLQVMRGDFLASLENDIKP
Sbjct: 541 EKAESLQVMRGDFLASLENDIKP 563


>gi|156564401 vesicle-fusing ATPase [Homo sapiens]
          Length = 744

 Score =  961 bits (2484), Expect = 0.0
 Identities = 488/490 (99%), Positives = 489/490 (99%)

Query: 74  MAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTFTLKTHPSVVPGSI 133
           MAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTFTLKTHPSVVPGSI
Sbjct: 1   MAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTFTLKTHPSVVPGSI 60

Query: 134 AFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAE 193
           AFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAE
Sbjct: 61  AFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAE 120

Query: 194 FIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGN 253
           FIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGN
Sbjct: 121 FIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGN 180

Query: 254 SQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVF 313
           SQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVF
Sbjct: 181 SQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVF 240

Query: 314 PPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEA 373
           PPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEA
Sbjct: 241 PPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEA 300

Query: 374 NIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDG 433
           NIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDG
Sbjct: 301 NIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDG 360

Query: 434 MEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLL 493
           +EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLL
Sbjct: 361 VEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLL 420

Query: 494 SADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVMRGDF 553
           SADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQV RGDF
Sbjct: 421 SADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDF 480

Query: 554 LASLENDIKP 563
           LASLENDIKP
Sbjct: 481 LASLENDIKP 490



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 36/130 (27%), Positives = 60/130 (46%), Gaps = 18/130 (13%)

Query: 329 ILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEA----NIRKLFADAEE 384
           +LL GPP  GKT LA +I +  N    K+ +     +K +G SE      ++K+F DA +
Sbjct: 539 VLLEGPPHSGKTALAAKIAEESNFPFIKICSP----DKMIGFSETAKCQAMKKIFDDAYK 594

Query: 385 EQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIG 444
            Q        L  ++ D+I+ +          + +    +  LL K     Q   +L+IG
Sbjct: 595 SQ--------LSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKK--APPQGRKLLIIG 644

Query: 445 MTNRPDLIDE 454
            T+R D++ E
Sbjct: 645 TTSRKDVLQE 654


>gi|239740963 PREDICTED: similar to N-ethylmaleimide-sensitive
           factor [Homo sapiens]
          Length = 405

 Score =  642 bits (1655), Expect = 0.0
 Identities = 321/321 (100%), Positives = 321/321 (100%)

Query: 1   MAPPLCPPRAPQAAAEPARAPCGARTPGTRPGTRASSRRLHACARAGGGGARAAGAGFAE 60
           MAPPLCPPRAPQAAAEPARAPCGARTPGTRPGTRASSRRLHACARAGGGGARAAGAGFAE
Sbjct: 1   MAPPLCPPRAPQAAAEPARAPCGARTPGTRPGTRASSRRLHACARAGGGGARAAGAGFAE 60

Query: 61  RRAAAAEPDVSAKMAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTF 120
           RRAAAAEPDVSAKMAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTF
Sbjct: 61  RRAAAAEPDVSAKMAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTF 120

Query: 121 TLKTHPSVVPGSIAFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSI 180
           TLKTHPSVVPGSIAFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSI
Sbjct: 121 TLKTHPSVVPGSIAFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSI 180

Query: 181 DSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATG 240
           DSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATG
Sbjct: 181 DSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATG 240

Query: 241 KRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEF 300
           KRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEF
Sbjct: 241 KRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEF 300

Query: 301 SDIFRRAFASRVFPPEIVEQM 321
           SDIFRRAFASRVFPPEIVEQM
Sbjct: 301 SDIFRRAFASRVFPPEIVEQM 321


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score =  161 bits (407), Expect = 2e-39
 Identities = 101/273 (36%), Positives = 152/273 (55%), Gaps = 22/273 (8%)

Query: 293 IGGLDKEFSDIFRRAFASRVFP---PEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKM 349
           IGGL+    D+ R       +P   P+   + G    KG+L YGPPGCGKTLLA+ I   
Sbjct: 479 IGGLE----DVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANE 534

Query: 350 LNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQ 409
             A    +  GPE+L  + GESEAN+R++F  A +        +   ++ FDE+D+I K 
Sbjct: 535 CQANFISI-KGPELLTMWFGESEANVREIFDKARQ--------AAPCVLFFDELDSIAKA 585

Query: 410 RGSMAGSTG-VHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEI 468
           RG   G  G   D V+NQ+L+++DGM    N+ +IG TNRPD+ID A+LRPGRL+  + I
Sbjct: 586 RGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYI 645

Query: 469 GLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNR 528
            LPDEK R+ IL  +  +      ++ DVD++ LA  T  FSGA+L  + + A   A+  
Sbjct: 646 PLPDEKSRVAILKANLRK----SPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRE 701

Query: 529 HIKASTKVEVDME-KAESLQVMRGDFLASLEND 560
            I++  + E + +    +++V   D +  +  D
Sbjct: 702 SIESEIRRERERQTNPSAMEVEEDDPVPEIRRD 734



 Score =  159 bits (403), Expect = 5e-39
 Identities = 102/263 (38%), Positives = 151/263 (57%), Gaps = 18/263 (6%)

Query: 293 IGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNA 352
           IGG  K+ + I +      +  P + + +G K  +GILLYGPPG GKTL+AR +     A
Sbjct: 206 IGGCRKQLAQI-KEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGA 264

Query: 353 REPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGS 412
               ++NGPEI++K  GESE+N+RK F +AE+            II  DE+DAI  +R  
Sbjct: 265 FF-FLINGPEIMSKLAGESESNLRKAFEEAEKNAPA--------IIFIDELDAIAPKREK 315

Query: 413 MAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPD 472
             G   V   +V+QLL+ +DG++Q  +++V+  TNRP+ ID AL R GR + +++IG+PD
Sbjct: 316 THGE--VERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPD 373

Query: 473 EKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKA 532
             GRL+IL IHT  M+    L+ DVD++++A ET    GA+L  L   A   A+ + +  
Sbjct: 374 ATGRLEILQIHTKNMK----LADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDL 429

Query: 533 STKVE--VDMEKAESLQVMRGDF 553
               +  +D E   SL V   DF
Sbjct: 430 IDLEDETIDAEVMNSLAVTMDDF 452


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score =  158 bits (399), Expect = 1e-38
 Identities = 100/269 (37%), Positives = 155/269 (57%), Gaps = 18/269 (6%)

Query: 265 SLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCK 324
           ++N I  +  +E    + N  W+     IGGL+     +  +A    +  PE   +MG +
Sbjct: 605 AMNDIRPSAMREIAIDVPNVSWS----DIGGLESIKLKL-EQAVEWPLKHPESFIRMGIQ 659

Query: 325 HVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEE 384
             KG+LLYGPPGC KT++A+ +    +      + GPE++NKYVGESE  +R+ F  A  
Sbjct: 660 PPKGVLLYGPPGCSKTMIAKALANE-SGLNFLAIKGPELMNKYVGESERAVRETFRKA-- 716

Query: 385 EQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIG 444
              R  A S   II FDE+DA+  +RGS  G+  V D V+ QLL+++DG+EQL ++ ++ 
Sbjct: 717 ---RAVAPS---IIFFDELDALAVERGSSLGAGNVADRVLAQLLTEMDGIEQLKDVTILA 770

Query: 445 MTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAV 504
            TNRPD ID+AL+RPGR++  + + LPD   R +I  +    M     +S +VD+ EL +
Sbjct: 771 ATNRPDRIDKALMRPGRIDRIIYVPLPDAATRREIFKLQFHSMP----VSNEVDLDELIL 826

Query: 505 ETKNFSGAELEGLVRAAQSTAMNRHIKAS 533
           +T  +SGAE+  + R A   A+   I+A+
Sbjct: 827 QTDAYSGAEIVAVCREAALLALEEDIQAN 855



 Score =  143 bits (360), Expect = 5e-34
 Identities = 96/274 (35%), Positives = 149/274 (54%), Gaps = 20/274 (7%)

Query: 293 IGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNA 352
           IGGL  +   I R      +  PE+ +  G    +G+LLYGPPG GKT++AR +   + A
Sbjct: 355 IGGLSSQLKAI-REIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIARAVANEVGA 413

Query: 353 REPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGS 412
               V+NGPEI++K+ GE+EA +R++FA+A              II  DE+DA+C +R  
Sbjct: 414 YV-SVINGPEIISKFYGETEAKLRQIFAEATLRHPS--------IIFIDELDALCPKREG 464

Query: 413 MAGSTGVHDTVVNQLLSKIDGMEQL---NNILVIGMTNRPDLIDEALLRPGRLEVKMEIG 469
                 V   VV  LL+ +DG+        +LV+G TNRP  +D AL RPGR + ++EIG
Sbjct: 465 AQNE--VEKRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIG 522

Query: 470 LPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRH 529
           +P+ + RL IL      +R    L  + ++ +LA     + GA+L+ L   A   A+ R 
Sbjct: 523 VPNAQDRLDILQ---KLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALRRI 579

Query: 530 IKASTKVEVDMEKAESLQVMRGDFLASLENDIKP 563
           +K    +  D++ A  +++   DFL ++ NDI+P
Sbjct: 580 LKKQPNLP-DVKVAGLVKITLKDFLQAM-NDIRP 611


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score =  150 bits (380), Expect = 2e-36
 Identities = 99/266 (37%), Positives = 149/266 (56%), Gaps = 19/266 (7%)

Query: 284 PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLA 343
           PD  +E   IGGLDK+  +I +      V  PE+ E +G    KG+LLYGPPG GKTLLA
Sbjct: 144 PDSTYEM--IGGLDKQIKEI-KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLA 200

Query: 344 RQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEI 403
           R +    +    +V +G E++ K++GE    +R+LF  A E            II  DEI
Sbjct: 201 RAVAHHTDCTFIRV-SGSELVQKFIGEGARMVRELFVMAREHAPS--------IIFMDEI 251

Query: 404 DAICKQR--GSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGR 461
           D+I   R  G   G + V  T++ +LL+++DG E   NI VI  TNR D++D ALLRPGR
Sbjct: 252 DSIGSSRLEGGSGGDSEVQRTML-ELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGR 310

Query: 462 LEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAA 521
           ++ K+E   P+E+ RL IL IH+ +M     L+  ++++++A      SGAE++G+   A
Sbjct: 311 IDRKIEFPPPNEEARLDILKIHSRKMN----LTRGINLRKIAELMPGASGAEVKGVCTEA 366

Query: 522 QSTAMNRHIKASTKVEVDMEKAESLQ 547
              A+       T+ + +M  A+ +Q
Sbjct: 367 GMYALRERRVHVTQEDFEMAVAKVMQ 392


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score =  147 bits (372), Expect = 2e-35
 Identities = 92/223 (41%), Positives = 137/223 (61%), Gaps = 23/223 (10%)

Query: 315  PEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKV----VNGPEILNKYVGE 370
            PE+   +  +   GILLYGPPG GKTLLA  I     ARE ++    V GPE+L+KY+G 
Sbjct: 863  PELFANLPIRQRTGILLYGPPGTGKTLLAGVI-----ARESRMNFISVKGPELLSKYIGA 917

Query: 371  SEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSK 430
            SE  +R +F  A+  +          I+ FDE ++I  +RG    +TGV D VVNQLL++
Sbjct: 918  SEQAVRDIFIRAQAAKPC--------ILFFDEFESIAPRRGH--DNTGVTDRVVNQLLTQ 967

Query: 431  IDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGH 490
            +DG+E L  + V+  T+RPDLID ALLRPGRL+  +    PD+  RL+IL++ +  +   
Sbjct: 968  LDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILNVLSDSLP-- 1025

Query: 491  QLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKAS 533
              L+ DVD++ +A  T +F+GA+L+ L+  AQ  A++  + +S
Sbjct: 1026 --LADDVDLQHVASVTDSFTGADLKALLYNAQLEALHGMLLSS 1066


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score =  146 bits (369), Expect = 4e-35
 Identities = 96/268 (35%), Positives = 147/268 (54%), Gaps = 19/268 (7%)

Query: 265 SLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCK 324
           +L+ +  +  +E   ++ N  W      IG L+ +  +    A  + V  P+  + +G  
Sbjct: 453 ALSSVQPSAKREGFVTVPNVTW----ADIGALE-DIREELTMAILAPVRNPDQFKALGLV 507

Query: 325 HVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEE 384
              G+LL GPPGCGKTLLA+ +          V  GPE+LN YVGESE  +R++F  A+ 
Sbjct: 508 TPAGVLLAGPPGCGKTLLAKAVANESGLNFISV-KGPELLNMYVGESERAVRQVFQRAK- 565

Query: 385 EQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIG 444
                  NS   +I FDE+DA+C +R      TG    VVNQLL+++DG+E    + ++ 
Sbjct: 566 -------NSAPCVIFFDEVDALCPRRSDR--ETGASVRVVNQLLTEMDGLEARQQVFIMA 616

Query: 445 MTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAV 504
            TNRPD+ID A+LRPGRL+  + +GLP    RL IL   T +      L ADV+++ +A 
Sbjct: 617 ATNRPDIIDPAILRPGRLDKTLFVGLPPPADRLAILKTIT-KNGTKPPLDADVNLEAIAG 675

Query: 505 ETK--NFSGAELEGLVRAAQSTAMNRHI 530
           + +   ++GA+L  LVR A   A+ + +
Sbjct: 676 DLRCDCYTGADLSALVREASICALRQEM 703



 Score =  124 bits (312), Expect = 2e-28
 Identities = 100/291 (34%), Positives = 142/291 (48%), Gaps = 34/291 (11%)

Query: 241 KRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEF 300
           KR+K ++  V G  +   +K          KAK +     I N  +      +GG D   
Sbjct: 123 KRKKEDLQEVDGEIEAVLQK----------KAKARGLEFQISNVKFE----DVGGNDMTL 168

Query: 301 SDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNG 360
            ++ +     R   PE+   +G    +G+LL+GPPGCGKTLLA  I   L+    KV   
Sbjct: 169 KEVCKMLIHMR--HPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGELDLPILKVA-A 225

Query: 361 PEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVH 420
           PEI++   GESE  +R+LF  A         ++   II  DEIDAI  +R     S  + 
Sbjct: 226 PEIVSGVSGESEQKLRELFEQA--------VSNAPCIIFIDEIDAITPKRE--VASKDME 275

Query: 421 DTVVNQLLSKIDGMEQLN---NILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRL 477
             +V QLL+ +D +  +     +LVIG TNRPD +D AL R GR + ++ +G+PDE  R 
Sbjct: 276 RRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRE 335

Query: 478 QILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNR 528
           +IL     ++R    L    D   LA  T  F GA+L  L R A   A+NR
Sbjct: 336 RILQTLCRKLR----LPQAFDFCHLAHLTPGFVGADLMALCREAAMCAVNR 382


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score =  146 bits (369), Expect = 4e-35
 Identities = 96/268 (35%), Positives = 147/268 (54%), Gaps = 19/268 (7%)

Query: 265 SLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCK 324
           +L+ +  +  +E   ++ N  W      IG L+ +  +    A  + V  P+  + +G  
Sbjct: 559 ALSSVQPSAKREGFVTVPNVTW----ADIGALE-DIREELTMAILAPVRNPDQFKALGLV 613

Query: 325 HVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEE 384
              G+LL GPPGCGKTLLA+ +          V  GPE+LN YVGESE  +R++F  A+ 
Sbjct: 614 TPAGVLLAGPPGCGKTLLAKAVANESGLNFISV-KGPELLNMYVGESERAVRQVFQRAK- 671

Query: 385 EQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIG 444
                  NS   +I FDE+DA+C +R      TG    VVNQLL+++DG+E    + ++ 
Sbjct: 672 -------NSAPCVIFFDEVDALCPRRSDR--ETGASVRVVNQLLTEMDGLEARQQVFIMA 722

Query: 445 MTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAV 504
            TNRPD+ID A+LRPGRL+  + +GLP    RL IL   T +      L ADV+++ +A 
Sbjct: 723 ATNRPDIIDPAILRPGRLDKTLFVGLPPPADRLAILKTIT-KNGTKPPLDADVNLEAIAG 781

Query: 505 ETK--NFSGAELEGLVRAAQSTAMNRHI 530
           + +   ++GA+L  LVR A   A+ + +
Sbjct: 782 DLRCDCYTGADLSALVREASICALRQEM 809



 Score =  124 bits (312), Expect = 2e-28
 Identities = 100/291 (34%), Positives = 142/291 (48%), Gaps = 34/291 (11%)

Query: 241 KRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEF 300
           KR+K ++  V G  +   +K          KAK +     I N  +      +GG D   
Sbjct: 229 KRKKEDLQEVDGEIEAVLQK----------KAKARGLEFQISNVKFE----DVGGNDMTL 274

Query: 301 SDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNG 360
            ++ +     R   PE+   +G    +G+LL+GPPGCGKTLLA  I   L+    KV   
Sbjct: 275 KEVCKMLIHMR--HPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGELDLPILKVA-A 331

Query: 361 PEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVH 420
           PEI++   GESE  +R+LF  A         ++   II  DEIDAI  +R     S  + 
Sbjct: 332 PEIVSGVSGESEQKLRELFEQA--------VSNAPCIIFIDEIDAITPKRE--VASKDME 381

Query: 421 DTVVNQLLSKIDGMEQLN---NILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRL 477
             +V QLL+ +D +  +     +LVIG TNRPD +D AL R GR + ++ +G+PDE  R 
Sbjct: 382 RRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRE 441

Query: 478 QILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNR 528
           +IL     ++R    L    D   LA  T  F GA+L  L R A   A+NR
Sbjct: 442 RILQTLCRKLR----LPQAFDFCHLAHLTPGFVGADLMALCREAAMCAVNR 488


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score =  144 bits (362), Expect = 3e-34
 Identities = 90/246 (36%), Positives = 143/246 (58%), Gaps = 18/246 (7%)

Query: 293 IGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNA 352
           IGGLD +  +I + +    +  PE  E+MG K  KG++LYGPPG GKTLLA+ +    +A
Sbjct: 187 IGGLDNQIQEI-KESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSA 245

Query: 353 REPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR-- 410
              +VV G E++ KY+G+    +R+LF  AEE            I+  DEIDAI  +R  
Sbjct: 246 TFLRVV-GSELIQKYLGDGPKLVRELFRVAEEHAPS--------IVFIDEIDAIGTKRYD 296

Query: 411 GSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGL 470
            +  G   +  T++ +LL+++DG +   ++ VI  TNR + +D AL+RPGR++ K+E  L
Sbjct: 297 SNSGGEREIQRTML-ELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPL 355

Query: 471 PDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAM-NRH 529
           PDEK + +I  IHT+RM     L+ DV + +L +   + SGA+++ +   A   A+  R 
Sbjct: 356 PDEKTKKRIFQIHTSRM----TLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERR 411

Query: 530 IKASTK 535
           +K + +
Sbjct: 412 MKVTNE 417


>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
          Length = 403

 Score =  139 bits (350), Expect = 7e-33
 Identities = 93/262 (35%), Positives = 140/262 (53%), Gaps = 23/262 (8%)

Query: 293 IGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNA 352
           IGGL ++  ++ R      +  PE+ +++G    KG LLYGPPG GKTLLAR +   L+ 
Sbjct: 149 IGGLSEQIREL-REVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDC 207

Query: 353 REPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGS 412
              KVV+   I++KY+GES   IR++F  A + Q          II  DEIDAI  +R S
Sbjct: 208 NFLKVVSS-SIVDKYIGESARLIREMFNYARDHQPC--------IIFMDEIDAIGGRRFS 258

Query: 413 MAGSTGVH-DTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLP 471
              S        + +LL+++DG + L+ + +I  TNRPD +D ALLRPGRL+ K+ I LP
Sbjct: 259 EGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLP 318

Query: 472 DEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGL--------VRAAQS 523
           +E+ RL IL IH   +  H     ++D + +   +  F+GA+L  +        +RA   
Sbjct: 319 NEQARLDILKIHAGPITKH----GEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHD 374

Query: 524 TAMNRHIKASTKVEVDMEKAES 545
             +      + +   D +K ES
Sbjct: 375 FVVQEDFMKAVRKVADSKKLES 396


>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
          Length = 439

 Score =  135 bits (339), Expect = 1e-31
 Identities = 93/264 (35%), Positives = 144/264 (54%), Gaps = 24/264 (9%)

Query: 293 IGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNA 352
           IGGLDK+  ++   A    +   E  E +G +  KG+L+YGPPG GKTLLAR       A
Sbjct: 188 IGGLDKQIQELVE-AIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKA 246

Query: 353 REPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR-- 410
              K+  GP+++  ++G+    +R  FA A+E+           II  DE+DAI  +R  
Sbjct: 247 TFLKLA-GPQLVQMFIGDGAKLVRDAFALAKEKAPS--------IIFIDELDAIGTKRFD 297

Query: 411 GSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGL 470
              AG   V  T++ +LL+++DG +    + VI  TNR D++D ALLR GRL+ K+E  +
Sbjct: 298 SEKAGDREVQRTML-ELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPM 356

Query: 471 PDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHI 530
           P+E+ R +I+ IH+ +M     +S DV+ +ELA  T +F+GA+ + +   A   A+ R  
Sbjct: 357 PNEEARARIMQIHSRKMN----VSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGA 412

Query: 531 KASTK-------VEVDMEKAESLQ 547
              T        +EV  +K  +LQ
Sbjct: 413 TELTHEDYMEGILEVQAKKKANLQ 436


>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
           [Homo sapiens]
          Length = 414

 Score =  134 bits (337), Expect = 2e-31
 Identities = 100/328 (30%), Positives = 164/328 (50%), Gaps = 27/328 (8%)

Query: 225 IEAMDPSILKGEPATGKRQKIEV------GLVVGNSQVAFEKAENSSLNLIGKAKTKENR 278
           +EA+D +       TG    + +       L+  N+ VA  K  N+ ++++         
Sbjct: 89  LEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIM 148

Query: 279 QSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCG 338
               +   +     IGG+D +  ++ R A    +   E+ +Q+G    +G+L+YGPPGCG
Sbjct: 149 MLTSDQKPDVMYADIGGMDIQKQEV-REAVELPLTHFELYKQIGIDPPRGVLMYGPPGCG 207

Query: 339 KTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHII 398
           KT+LA+ +     A   +VV G E + KY+GE    +R +F        RL   +   II
Sbjct: 208 KTMLAKAVAHHTTAAFIRVV-GSEFVQKYLGEGPRMVRDVF--------RLAKENAPAII 258

Query: 399 IFDEIDAICKQR-GSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALL 457
             DEIDAI  +R  +  G+      ++ +LL+++DG +Q  N+ VI  TNR D +D ALL
Sbjct: 259 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALL 318

Query: 458 RPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGL 517
           RPGRL+ K+E  LPD + +  I    T++M     LS +VD+++        SGA++  +
Sbjct: 319 RPGRLDRKIEFPLPDRRQKRLIFSTITSKMN----LSEEVDLEDYVARPDKISGADINSI 374

Query: 518 VRAAQSTAM--NRHIKASTKVEVDMEKA 543
            + +   A+  NR+I  +     D EKA
Sbjct: 375 CQESGMLAVRENRYIVLAK----DFEKA 398



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 18/71 (25%), Positives = 40/71 (56%), Gaps = 5/71 (7%)

Query: 362 EILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHD 421
           E+  +Y+ + + N++K F  A+EE +R+     + ++I   ++A+ +    +  +TG + 
Sbjct: 51  EVQEEYIKDEQKNLKKEFLHAQEEVKRI---QSIPLVIGQFLEAVDQNTAIVGSTTGSNY 107

Query: 422 TVVNQLLSKID 432
            V  ++LS ID
Sbjct: 108 YV--RILSTID 116


>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
           sapiens]
          Length = 387

 Score =  134 bits (337), Expect = 2e-31
 Identities = 100/328 (30%), Positives = 164/328 (50%), Gaps = 27/328 (8%)

Query: 225 IEAMDPSILKGEPATGKRQKIEV------GLVVGNSQVAFEKAENSSLNLIGKAKTKENR 278
           +EA+D +       TG    + +       L+  N+ VA  K  N+ ++++         
Sbjct: 62  LEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIM 121

Query: 279 QSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCG 338
               +   +     IGG+D +  ++ R A    +   E+ +Q+G    +G+L+YGPPGCG
Sbjct: 122 MLTSDQKPDVMYADIGGMDIQKQEV-REAVELPLTHFELYKQIGIDPPRGVLMYGPPGCG 180

Query: 339 KTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHII 398
           KT+LA+ +     A   +VV G E + KY+GE    +R +F        RL   +   II
Sbjct: 181 KTMLAKAVAHHTTAAFIRVV-GSEFVQKYLGEGPRMVRDVF--------RLAKENAPAII 231

Query: 399 IFDEIDAICKQR-GSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALL 457
             DEIDAI  +R  +  G+      ++ +LL+++DG +Q  N+ VI  TNR D +D ALL
Sbjct: 232 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALL 291

Query: 458 RPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGL 517
           RPGRL+ K+E  LPD + +  I    T++M     LS +VD+++        SGA++  +
Sbjct: 292 RPGRLDRKIEFPLPDRRQKRLIFSTITSKMN----LSEEVDLEDYVARPDKISGADINSI 347

Query: 518 VRAAQSTAM--NRHIKASTKVEVDMEKA 543
            + +   A+  NR+I  +     D EKA
Sbjct: 348 CQESGMLAVRENRYIVLAK----DFEKA 371


>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
          Length = 418

 Score =  134 bits (337), Expect = 2e-31
 Identities = 100/328 (30%), Positives = 164/328 (50%), Gaps = 27/328 (8%)

Query: 225 IEAMDPSILKGEPATGKRQKIEV------GLVVGNSQVAFEKAENSSLNLIGKAKTKENR 278
           +EA+D +       TG    + +       L+  N+ VA  K  N+ ++++         
Sbjct: 93  LEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIM 152

Query: 279 QSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCG 338
               +   +     IGG+D +  ++ R A    +   E+ +Q+G    +G+L+YGPPGCG
Sbjct: 153 MLTSDQKPDVMYADIGGMDIQKQEV-REAVELPLTHFELYKQIGIDPPRGVLMYGPPGCG 211

Query: 339 KTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHII 398
           KT+LA+ +     A   +VV G E + KY+GE    +R +F        RL   +   II
Sbjct: 212 KTMLAKAVAHHTTAAFIRVV-GSEFVQKYLGEGPRMVRDVF--------RLAKENAPAII 262

Query: 399 IFDEIDAICKQR-GSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALL 457
             DEIDAI  +R  +  G+      ++ +LL+++DG +Q  N+ VI  TNR D +D ALL
Sbjct: 263 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALL 322

Query: 458 RPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGL 517
           RPGRL+ K+E  LPD + +  I    T++M     LS +VD+++        SGA++  +
Sbjct: 323 RPGRLDRKIEFPLPDRRQKRLIFSTITSKMN----LSEEVDLEDYVARPDKISGADINSI 378

Query: 518 VRAAQSTAM--NRHIKASTKVEVDMEKA 543
            + +   A+  NR+I  +     D EKA
Sbjct: 379 CQESGMLAVRENRYIVLAK----DFEKA 402



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 18/71 (25%), Positives = 40/71 (56%), Gaps = 5/71 (7%)

Query: 362 EILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHD 421
           E+  +Y+ + + N++K F  A+EE +R+     + ++I   ++A+ +    +  +TG + 
Sbjct: 55  EVQEEYIKDEQKNLKKEFLHAQEEVKRI---QSIPLVIGQFLEAVDQNTAIVGSTTGSNY 111

Query: 422 TVVNQLLSKID 432
            V  ++LS ID
Sbjct: 112 YV--RILSTID 120


>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
          Length = 1458

 Score =  134 bits (336), Expect = 3e-31
 Identities = 95/259 (36%), Positives = 138/259 (53%), Gaps = 27/259 (10%)

Query: 312 VFP---PEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVV----NGPEIL 364
           VFP   PEI E+   +  +G L YGPPG GKTL+AR +    +  + KV      G + L
Sbjct: 417 VFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCL 476

Query: 365 NKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVV 424
           +K+VGESE  +R LF     +Q  L   S   II FDEID +   R S      +H ++V
Sbjct: 477 SKWVGESERQLRLLF-----DQAYLMRPS---IIFFDEIDGLAPVRSSRQDQ--IHSSIV 526

Query: 425 NQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHT 484
           + LL+ +DG++    I+VIG TNR D ID AL RPGR + +    LPD+K R  IL IHT
Sbjct: 527 STLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHT 586

Query: 485 ARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRH----IKASTKVEVDM 540
              R      +D  + ELA +   + GA+++ L   A   A+ R       +S K+++D+
Sbjct: 587 ---RDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALRRRYPQIYASSHKLQLDV 643

Query: 541 EKAESLQVMRGDFLASLEN 559
               S+ +   DF  +++N
Sbjct: 644 ---SSIVLSAQDFYHAMQN 659



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 33/129 (25%), Positives = 51/129 (39%), Gaps = 11/129 (8%)

Query: 7   PPRAPQAAAEPARAPCGARTPGTRPGTRASSRRLHACARAGGGGARAAGAGFAERRAAAA 66
           P   P A AEP      +    +R  TR+S  R  +C  A  GG+  AG    E R    
Sbjct: 19  PGPGPGAGAEPGATGGSSHFISSR--TRSSKTRAASCPAAKAGGSGGAGVTLDEARKVEV 76

Query: 67  EPDVS----AKMAGRSM-QAARCPTDELSLTNCAVVNEKDFQSGQHVIV----RTSPNHR 117
           +  +S    +  A R++ Q      D+    +     E +  +GQ  +      T PN  
Sbjct: 77  DGSLSDSHVSPPAKRTLKQPDSVCKDKSKSRSTGQREEWNLSTGQARLTSQPGATLPNGH 136

Query: 118 YTFTLKTHP 126
              +L++HP
Sbjct: 137 SGLSLRSHP 145


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score =  132 bits (332), Expect = 8e-31
 Identities = 92/280 (32%), Positives = 142/280 (50%), Gaps = 31/280 (11%)

Query: 293 IGGLDKEFSDIFRRAFASRVFP---PEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKM 349
           +GGL    + +        VFP   PE+ E+   +  +G L YGPPG GKTL+AR +   
Sbjct: 428 VGGLSNHIAALKEMV----VFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALANE 483

Query: 350 LNAREPKVV----NGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDA 405
            +  + +V      G + L+K+VGESE  +R LF  A + +          II FDEID 
Sbjct: 484 CSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPS--------IIFFDEIDG 535

Query: 406 ICKQRGSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVK 465
           +   R S      +H ++V+ LL+ +DG++    I+VIG TNR D ID AL RPGR + +
Sbjct: 536 LAPVRSSRQDQ--IHSSIVSTLLALMDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDRE 593

Query: 466 MEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTA 525
               LPD++ R +IL IHT       L   D  ++ELA     + GA+++ +   A   A
Sbjct: 594 FLFSLPDKEARKEILKIHTRDWNPKPL---DTFLEELAENCVGYCGADIKSICAEAALCA 650

Query: 526 MNRH----IKASTKVEVDMEKAESLQVMRGDFLASLENDI 561
           + R        S K+++D+    S+ +   DF  +++  I
Sbjct: 651 LRRRYPQIYTTSEKLQLDL---SSINISAKDFEVAMQKMI 687


>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
          Length = 753

 Score =  130 bits (327), Expect = 3e-30
 Identities = 86/234 (36%), Positives = 127/234 (54%), Gaps = 15/234 (6%)

Query: 293 IGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNA 352
           +GGL  E +D  R      +  P  +  +G    +G+LL GPPG GKT L R + +   A
Sbjct: 202 LGGLS-EAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGA 260

Query: 353 REPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGS 412
            E   V+ P +     GE+E N+R++F  A E      A+ G  ++  DE+DA+C QRGS
Sbjct: 261 -ELLAVSAPALQGSRPGETEENVRRVFQRAREL-----ASRGPSLLFLDEMDALCPQRGS 314

Query: 413 MAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPD 472
            A  +     VV Q+L+ +DG      ++V+G TNRPD +D AL RPGR + ++ IG P 
Sbjct: 315 RAPES----RVVAQVLTLLDGASGDREVVVVGATNRPDALDPALRRPGRFDREVVIGTPT 370

Query: 473 EKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAM 526
            K R +IL + T++M     +S+ VD+  LA  T  + GA+L  L R A   A+
Sbjct: 371 LKQRKEILQVITSKMP----ISSHVDLGLLAEMTVGYVGADLTALCREAAMHAL 420



 Score =  122 bits (307), Expect = 7e-28
 Identities = 86/244 (35%), Positives = 126/244 (51%), Gaps = 33/244 (13%)

Query: 313 FPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESE 372
           FP E V +MG    KG+LLYGPPGC KT L R +    +     V +G ++ + +VG+SE
Sbjct: 486 FPWEFV-RMGLTQPKGVLLYGPPGCAKTTLVRALATSCHCSFVSV-SGADLFSPFVGDSE 543

Query: 373 ANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKID 432
             + ++F  A          S   I+  DEID+I   R +      V + V++ LL+++D
Sbjct: 544 KVLSQIFRQARA--------STPAILFLDEIDSILGARSASKTGCDVQERVLSVLLNELD 595

Query: 433 GM------------------EQLN-NILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDE 473
           G+                  E  N ++++I  TNRPD++D ALLRPGRL+  + I  PD 
Sbjct: 596 GVGLKTIERRGSKSSQQEFQEVFNRSVMIIAATNRPDVLDTALLRPGRLDKIIYIPPPDH 655

Query: 474 KGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKAS 533
           KGRL IL + T  M     +  DV ++ LA ET  FSGA+L  L   A   A+  +   +
Sbjct: 656 KGRLSILKVCTKTMP----IGPDVSLENLAAETCFFSGADLRNLCTEAALLALQENGLDA 711

Query: 534 TKVE 537
           T V+
Sbjct: 712 TTVK 715


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score =  130 bits (327), Expect = 3e-30
 Identities = 78/204 (38%), Positives = 116/204 (56%), Gaps = 13/204 (6%)

Query: 328 GILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQR 387
           G+LL+GPPG GKTLLA+ +    +     V  GPE++N YVG+SE N+R++FA A     
Sbjct: 739 GLLLHGPPGTGKTLLAKAVATECSLTFLSV-KGPELINMYVGQSEENVREVFARARA--- 794

Query: 388 RLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTN 447
                +   II FDE+D++   RG    S GV D VV+QLL+++DG+    ++ VIG TN
Sbjct: 795 -----AAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATN 849

Query: 448 RPDLIDEALLRPGRLEVKMEIGL-PDEKGRLQILHIHTARMRGHQLLSADVDIKELAVET 506
           RPDL+D ALLRPGR +  + +G   D   +L++L   T + +    +S    +  L    
Sbjct: 850 RPDLLDPALLRPGRFDKLVFVGANEDRASQLRVLSAITRKFKLEPSVSL---VNVLDCCP 906

Query: 507 KNFSGAELEGLVRAAQSTAMNRHI 530
              +GA+L  L   A + A+ R +
Sbjct: 907 PQLTGADLYSLCSDAMTAALKRRV 930



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 51/202 (25%), Positives = 80/202 (39%), Gaps = 20/202 (9%)

Query: 329 ILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRR 388
           +LL GPPGCGKT +       L     KV     +  +  G  E  ++ +F+ A   +  
Sbjct: 466 VLLRGPPGCGKTTVVAAACSHLGLHLLKVPCS-SLCAESSGAVETKLQAIFSRARRCRPA 524

Query: 389 LGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNR 448
                   +++   +D + + R  +     V   V+  LL   D +     ++V+  T+R
Sbjct: 525 --------VLLLTAVDLLGRDRDGLGEDARVM-AVLRHLLLNEDPLNSCPPLMVVATTSR 575

Query: 449 -PDL-IDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVET 506
             DL  D     P  LEV        E  RL IL   TA    H  L  +V++ +LA   
Sbjct: 576 AQDLPADVQTAFPHELEVP----ALSEGQRLSILRALTA----HLPLGQEVNLAQLARRC 627

Query: 507 KNFSGAELEGLVRAAQSTAMNR 528
             F   +L  L+  +   A  R
Sbjct: 628 AGFVVGDLYALLTHSSRAACTR 649


>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score =  130 bits (327), Expect = 3e-30
 Identities = 89/245 (36%), Positives = 130/245 (53%), Gaps = 17/245 (6%)

Query: 293 IGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNA 352
           +GG  KE  +  R    + +  PE    +G +  KG+LL+GPPG GKTL AR +    +A
Sbjct: 177 VGGC-KEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDA 235

Query: 353 REPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR-- 410
              +V+ G E++ KYVGE    +R+LF  A  ++  L        I FDEIDAI   R  
Sbjct: 236 CFIRVI-GSELVQKYVGEGARMVRELFEMARTKKACL--------IFFDEIDAIGGARFD 286

Query: 411 GSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGL 470
               G   V  T++ +L++++DG +   NI V+  TNRPD +D AL+RPGRL+ K+E  L
Sbjct: 287 DGAGGDNEVQRTML-ELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSL 345

Query: 471 PDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHI 530
           PD +GR  I  IH   M     +  D+  + LA    N +GAE+  +   A   A+    
Sbjct: 346 PDLEGRTHIFKIHARSMS----VERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARR 401

Query: 531 KASTK 535
           K +T+
Sbjct: 402 KIATE 406


>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
          Length = 797

 Score =  129 bits (324), Expect = 7e-30
 Identities = 82/221 (37%), Positives = 118/221 (53%), Gaps = 13/221 (5%)

Query: 315 PEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKV-VNGPEILNKYVGESEA 373
           P+  + +G K  KG +L GPPG GKTLLA+      N   P + V+G E L  +VG   A
Sbjct: 330 PKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANV--PFITVSGSEFLEMFVGVGPA 387

Query: 374 NIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRG-SMAGSTGVHDTVVNQLLSKID 432
            +R LFA        L   +   I+  DEIDA+ ++RG    G     +  +NQLL ++D
Sbjct: 388 RVRDLFA--------LARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMD 439

Query: 433 GMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQL 492
           G     N++++  TNRPD++D ALLRPGR + ++ IG PD KGR  I  +H   ++    
Sbjct: 440 GFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDST 499

Query: 493 LSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKAS 533
           L  D   ++LA  T  FSGA++  +   A   A  RH+  S
Sbjct: 500 LEKDKLARKLASLTPGFSGADVANVCNEAALIAA-RHLSDS 539


>gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]
          Length = 795

 Score =  115 bits (289), Expect = 8e-26
 Identities = 89/254 (35%), Positives = 130/254 (51%), Gaps = 21/254 (8%)

Query: 290 KMGIGGLDKEFSDIFR-----RAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLAR 344
           KMG G   K+ + +       R F   +  PE   Q+G K  KG LL GPPGCGKTLLA+
Sbjct: 301 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK 360

Query: 345 QIGKMLNAREPKV-VNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEI 403
            +     A+ P + + GPE +    G   A +R LF +A              I+  DEI
Sbjct: 361 AVAT--EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPC--------IVYIDEI 410

Query: 404 DAICKQRGS-MAG-STGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGR 461
           DA+ K+R + M+G S    +  +NQLL ++DGM   ++++V+  TNR D++D AL+RPGR
Sbjct: 411 DAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGR 470

Query: 462 LEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLV-RA 520
           L+  + I LP  + R +I   H   ++  Q  S+    + LA  T  FSGA++  +   A
Sbjct: 471 LDRHVFIDLPTLQERREIFEQHLKSLKLTQ--SSTFYSQRLAELTPGFSGADIANICNEA 528

Query: 521 AQSTAMNRHIKAST 534
           A   A   H    T
Sbjct: 529 ALHAAREGHTSVHT 542


>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
          Length = 773

 Score =  114 bits (286), Expect = 2e-25
 Identities = 88/252 (34%), Positives = 132/252 (52%), Gaps = 25/252 (9%)

Query: 315 PEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKV----VNGPEILNKYVGE 370
           P+    +G K  KGILL GPPG GKTLLAR +     A E  V     +G E    +VG 
Sbjct: 361 PQKFTILGGKLPKGILLVGPPGTGKTLLARAV-----AGEADVPFYYASGSEFDEMFVGV 415

Query: 371 SEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSK 430
             + IR LF +A+       AN+   +I  DE+D++  +R           T+ NQLL++
Sbjct: 416 GASRIRNLFREAK-------ANAPC-VIFIDELDSVGGKRIESPMHPYSRQTI-NQLLAE 466

Query: 431 IDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGH 490
           +DG +    +++IG TN P+ +D AL+RPGR ++++ +  PD KGR +IL  +  +++  
Sbjct: 467 MDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFD 526

Query: 491 QLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVMR 550
           Q     VD + +A  T  FSGAELE LV  A   A     +  T  E++  K    +++ 
Sbjct: 527 Q----SVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKD---KILM 579

Query: 551 GDFLASLENDIK 562
           G    S+E D K
Sbjct: 580 GPERRSVEIDNK 591


>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
          Length = 716

 Score =  114 bits (286), Expect = 2e-25
 Identities = 88/252 (34%), Positives = 132/252 (52%), Gaps = 25/252 (9%)

Query: 315 PEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKV----VNGPEILNKYVGE 370
           P+    +G K  KGILL GPPG GKTLLAR +     A E  V     +G E    +VG 
Sbjct: 304 PQKFTILGGKLPKGILLVGPPGTGKTLLARAV-----AGEADVPFYYASGSEFDEMFVGV 358

Query: 371 SEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSK 430
             + IR LF +A+       AN+   +I  DE+D++  +R           T+ NQLL++
Sbjct: 359 GASRIRNLFREAK-------ANAPC-VIFIDELDSVGGKRIESPMHPYSRQTI-NQLLAE 409

Query: 431 IDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGH 490
           +DG +    +++IG TN P+ +D AL+RPGR ++++ +  PD KGR +IL  +  +++  
Sbjct: 410 MDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFD 469

Query: 491 QLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVMR 550
           Q     VD + +A  T  FSGAELE LV  A   A     +  T  E++  K    +++ 
Sbjct: 470 Q----SVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKD---KILM 522

Query: 551 GDFLASLENDIK 562
           G    S+E D K
Sbjct: 523 GPERRSVEIDNK 534


>gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]
          Length = 415

 Score =  112 bits (280), Expect = 9e-25
 Identities = 76/244 (31%), Positives = 125/244 (51%), Gaps = 31/244 (12%)

Query: 294 GGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAR 353
           GGLD +  +I + +    +  PE  E+MG K  KG++L GPPG    L            
Sbjct: 175 GGLDNQIQEI-KESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLR----------- 222

Query: 354 EPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR--G 411
               V G E++ KY+G+    +R++F  AEE            I+  DEI+AI  +R   
Sbjct: 223 ----VVGSELIQKYLGDGPKLVRQVFQVAEEHAPS--------IMFTDEIEAIGTKRYDS 270

Query: 412 SMAGSTGVHDTVVN-QLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGL 470
           +  G   +  T++  +LL+++ G +   ++ VI  T + + +D  L+RPGR++ K+E  L
Sbjct: 271 NSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHL 330

Query: 471 PDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHI 530
           PDEK +  I  IHT+RM     L+ DV + +L +   +FSGA+++ +   A   A+  H 
Sbjct: 331 PDEKTKKHIFQIHTSRM----TLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHR 386

Query: 531 KAST 534
             +T
Sbjct: 387 MKAT 390


>gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]
          Length = 415

 Score =  112 bits (280), Expect = 9e-25
 Identities = 76/244 (31%), Positives = 125/244 (51%), Gaps = 31/244 (12%)

Query: 294 GGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAR 353
           GGLD +  +I + +    +  PE  E+MG K  KG++L GPPG    L            
Sbjct: 175 GGLDNQIQEI-KESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLR----------- 222

Query: 354 EPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR--G 411
               V G E++ KY+G+    +R++F  AEE            I+  DEI+AI  +R   
Sbjct: 223 ----VVGSELIQKYLGDGPKLVRQVFQVAEEHAPS--------IMFTDEIEAIGTKRYDS 270

Query: 412 SMAGSTGVHDTVVN-QLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGL 470
           +  G   +  T++  +LL+++ G +   ++ VI  T + + +D  L+RPGR++ K+E  L
Sbjct: 271 NSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHL 330

Query: 471 PDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHI 530
           PDEK +  I  IHT+RM     L+ DV + +L +   +FSGA+++ +   A   A+  H 
Sbjct: 331 PDEKTKKHIFQIHTSRM----TLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHR 386

Query: 531 KAST 534
             +T
Sbjct: 387 MKAT 390


>gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo
           sapiens]
          Length = 415

 Score =  112 bits (280), Expect = 9e-25
 Identities = 76/244 (31%), Positives = 125/244 (51%), Gaps = 31/244 (12%)

Query: 294 GGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAR 353
           GGLD +  +I + +    +  PE  E+MG K  KG++L GPPG    L            
Sbjct: 175 GGLDNQIQEI-KESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLR----------- 222

Query: 354 EPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR--G 411
               V G E++ KY+G+    +R++F  AEE            I+  DEI+AI  +R   
Sbjct: 223 ----VVGSELIQKYLGDGPKLVRQVFQVAEEHAPS--------IMFTDEIEAIGTKRYDS 270

Query: 412 SMAGSTGVHDTVVN-QLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGL 470
           +  G   +  T++  +LL+++ G +   ++ VI  T + + +D  L+RPGR++ K+E  L
Sbjct: 271 NSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHL 330

Query: 471 PDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHI 530
           PDEK +  I  IHT+RM     L+ DV + +L +   +FSGA+++ +   A   A+  H 
Sbjct: 331 PDEKTKKHIFQIHTSRM----TLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHR 386

Query: 531 KAST 534
             +T
Sbjct: 387 MKAT 390


>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  106 bits (264), Expect = 6e-23
 Identities = 82/245 (33%), Positives = 127/245 (51%), Gaps = 25/245 (10%)

Query: 327 KGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQ 386
           KG+L+ GPPG GKT+LA+ +           V+   + +KY GESE  +R LF     E 
Sbjct: 242 KGVLMVGPPGTGKTMLAKAVATECGTTFFN-VSSSTLTSKYRGESEKLVRLLF-----EM 295

Query: 387 RRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGM-------EQLNN 439
            R  A +    I  DEID+IC +RG+ +        V ++LL ++DG+       +    
Sbjct: 296 ARFYAPT---TIFIDEIDSICSRRGT-SDEHEASRRVKSELLIQMDGVGGALENDDPSKM 351

Query: 440 ILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDI 499
           ++V+  TN P  IDEAL R  RLE ++ I LP  KGR ++L I+   +     L  D+ +
Sbjct: 352 VMVLAATNFPWDIDEALRR--RLEKRIYIPLPTAKGRAELLKINLREVE----LDPDIQL 405

Query: 500 KELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQ--VMRGDFLASL 557
           +++A + + +SGA++  + R A   AM R I   +  E+     E LQ  V +GDF  +L
Sbjct: 406 EDIAEKIEGYSGADITNVCRDASLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFELAL 465

Query: 558 ENDIK 562
           +   K
Sbjct: 466 KKIAK 470


>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  106 bits (264), Expect = 6e-23
 Identities = 82/245 (33%), Positives = 127/245 (51%), Gaps = 25/245 (10%)

Query: 327 KGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQ 386
           KG+L+ GPPG GKT+LA+ +           V+   + +KY GESE  +R LF     E 
Sbjct: 242 KGVLMVGPPGTGKTMLAKAVATECGTTFFN-VSSSTLTSKYRGESEKLVRLLF-----EM 295

Query: 387 RRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGM-------EQLNN 439
            R  A +    I  DEID+IC +RG+ +        V ++LL ++DG+       +    
Sbjct: 296 ARFYAPT---TIFIDEIDSICSRRGT-SDEHEASRRVKSELLIQMDGVGGALENDDPSKM 351

Query: 440 ILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDI 499
           ++V+  TN P  IDEAL R  RLE ++ I LP  KGR ++L I+   +     L  D+ +
Sbjct: 352 VMVLAATNFPWDIDEALRR--RLEKRIYIPLPTAKGRAELLKINLREVE----LDPDIQL 405

Query: 500 KELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQ--VMRGDFLASL 557
           +++A + + +SGA++  + R A   AM R I   +  E+     E LQ  V +GDF  +L
Sbjct: 406 EDIAEKIEGYSGADITNVCRDASLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFELAL 465

Query: 558 ENDIK 562
           +   K
Sbjct: 466 KKIAK 470


>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
          Length = 491

 Score =  100 bits (248), Expect = 5e-21
 Identities = 79/223 (35%), Positives = 116/223 (52%), Gaps = 31/223 (13%)

Query: 327 KGILLYGPPGCGKTLLARQIGKMLNAREPKV----VNGPEILNKYVGESEANIRKLFADA 382
           KG+L+ GPPG GKTLLA+ +     A E K     V+   + +KY GESE  +R LF   
Sbjct: 243 KGVLMVGPPGTGKTLLAKAV-----ATECKTTFFNVSSSTLTSKYRGESEKLVRLLF--- 294

Query: 383 EEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGM-------E 435
             E  R  + +    I  DEID+IC +RG+ +        V  +LL ++DG+       +
Sbjct: 295 --EMARFYSPA---TIFIDEIDSICSRRGT-SEEHEASRRVKAELLVQMDGVGGTSENDD 348

Query: 436 QLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSA 495
               ++V+  TN P  IDEAL R  RLE ++ I LP  KGR ++L I    +     L+ 
Sbjct: 349 PSKMVMVLAATNFPWDIDEALRR--RLEKRIYIPLPSAKGREELLRISLRELE----LAD 402

Query: 496 DVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEV 538
           DVD+  +A   + +SGA++  + R A   AM R I+  T  E+
Sbjct: 403 DVDLASIAENMEGYSGADITNVCRDASLMAMRRRIEGLTPEEI 445


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,697,159
Number of Sequences: 37866
Number of extensions: 927919
Number of successful extensions: 5845
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 168
Number of HSP's that attempted gapping in prelim test: 5387
Number of HSP's gapped (non-prelim): 443
length of query: 563
length of database: 18,247,518
effective HSP length: 107
effective length of query: 456
effective length of database: 14,195,856
effective search space: 6473310336
effective search space used: 6473310336
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.