Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 19923395
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923395 beta-site APP-cleaving enzyme 2 isoform A
preproprotein [Homo sapiens]
(518 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprot... 1039 0.0
gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprot... 909 0.0
gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprot... 761 0.0
gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprote... 452 e-127
gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprot... 405 e-113
gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprot... 385 e-107
gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprot... 267 2e-71
gi|4505757 progastricsin (pepsinogen C) [Homo sapiens] 119 9e-27
gi|4506475 renin preproprotein [Homo sapiens] 104 2e-22
gi|4503143 cathepsin D preproprotein [Homo sapiens] 103 3e-22
gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens] 100 2e-21
gi|119372302 pepsinogen 4, group I [Homo sapiens] 100 3e-21
gi|119372298 pepsinogen 3, group I [Homo sapiens] 100 3e-21
gi|23943854 pepsinogen 5, group I [Homo sapiens] 100 3e-21
gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens] 79 8e-15
gi|4758754 napsin A preproprotein [Homo sapiens] 77 4e-14
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 34 0.37
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 34 0.37
gi|39995080 hypothetical protein LOC79567 [Homo sapiens] 33 0.63
gi|197927448 WD repeat domain 6 protein [Homo sapiens] 33 0.63
gi|38683860 insulin receptor substrate 2 [Homo sapiens] 33 0.82
gi|19924099 synapsin I isoform Ia [Homo sapiens] 33 0.82
gi|19924097 synapsin I isoform Ib [Homo sapiens] 33 0.82
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] 32 1.1
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] 32 1.1
gi|239753114 PREDICTED: hypothetical protein [Homo sapiens] 32 1.4
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 32 1.4
gi|124378039 SEC16 homolog A [Homo sapiens] 31 2.4
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 31 2.4
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 30 5.3
>gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprotein
[Homo sapiens]
Length = 518
Score = 1039 bits (2687), Expect = 0.0
Identities = 518/518 (100%), Positives = 518/518 (100%)
Query: 1 MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60
MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL
Sbjct: 1 MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60
Query: 61 ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120
ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG
Sbjct: 61 ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120
Query: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180
TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI
Sbjct: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180
Query: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240
FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA
Sbjct: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240
Query: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300
GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA
Sbjct: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300
Query: 301 IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI 360
IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI
Sbjct: 301 IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI 360
Query: 361 YLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFD 420
YLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFD
Sbjct: 361 YLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFD 420
Query: 421 RAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCG 480
RAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCG
Sbjct: 421 RAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCG 480
Query: 481 AILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK 518
AILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK
Sbjct: 481 AILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK 518
>gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprotein
[Homo sapiens]
Length = 468
Score = 909 bits (2349), Expect = 0.0
Identities = 468/518 (90%), Positives = 468/518 (90%), Gaps = 50/518 (9%)
Query: 1 MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60
MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL
Sbjct: 1 MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60
Query: 61 ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120
ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG
Sbjct: 61 ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120
Query: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180
TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI
Sbjct: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180
Query: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240
FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA
Sbjct: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240
Query: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300
GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA
Sbjct: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300
Query: 301 IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI 360
IVDSGTTLLRLPQKVFDAVVEAVARASL
Sbjct: 301 IVDSGTTLLRLPQKVFDAVVEAVARASL-------------------------------- 328
Query: 361 YLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFD 420
LYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFD
Sbjct: 329 ------------------LYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFD 370
Query: 421 RAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCG 480
RAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCG
Sbjct: 371 RAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCG 430
Query: 481 AILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK 518
AILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK
Sbjct: 431 AILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK 468
>gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprotein
[Homo sapiens]
Length = 396
Score = 761 bits (1966), Expect = 0.0
Identities = 378/378 (100%), Positives = 378/378 (100%)
Query: 1 MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60
MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL
Sbjct: 1 MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL 60
Query: 61 ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120
ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG
Sbjct: 61 ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG 120
Query: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180
TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI
Sbjct: 121 TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI 180
Query: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240
FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA
Sbjct: 181 FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA 240
Query: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300
GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA
Sbjct: 241 GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA 300
Query: 301 IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI 360
IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI
Sbjct: 301 IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI 360
Query: 361 YLRDENSSRSFRITILPQ 378
YLRDENSSRSFRITILPQ
Sbjct: 361 YLRDENSSRSFRITILPQ 378
>gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprotein
[Homo sapiens]
Length = 501
Score = 452 bits (1164), Expect = e-127
Identities = 222/448 (49%), Positives = 302/448 (67%), Gaps = 7/448 (1%)
Query: 71 PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
P +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV PH ++ Y+
Sbjct: 54 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113
Query: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPG 190
+ SSTYR V V YTQG W G +G DLV+IP G N + NIA I ES+ FF+ G
Sbjct: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFING 173
Query: 191 IKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGS---GTNGG 247
W GILGLAYA +A+P SLE FFDSLV Q ++PN+FS+Q+CGAG P+ S + GG
Sbjct: 174 SNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGG 233
Query: 248 SLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTT 307
S+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L +DC+EYN DK+IVDSGTT
Sbjct: 234 SMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTT 293
Query: 308 LLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENS 367
LRLP+KVF+A V+++ AS +F DGFW G QL CW TPW+ FP IS+YL E +
Sbjct: 294 NLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVT 353
Query: 368 SRSFRITILPQLYIQPMMGAGLNY-ECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRV 426
++SFRITILPQ Y++P+ + +CY+F IS S+ V+GA +MEGFYV+FDRA+KR+
Sbjct: 354 NQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRI 413
Query: 427 GFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVL 486
GFA S C + + GPF T D+ E L ++Y + ++C A+ ++
Sbjct: 414 GFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAIC-ALFMLP 472
Query: 487 IVLLLLPFRCQR--RPRDPEVVNDESSL 512
+ L++ +RC R R + + +D S L
Sbjct: 473 LCLMVCQWRCLRCLRQQHDDFADDISLL 500
>gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprotein
[Homo sapiens]
Length = 476
Score = 405 bits (1040), Expect = e-113
Identities = 206/448 (45%), Positives = 282/448 (62%), Gaps = 32/448 (7%)
Query: 71 PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
P +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV PH ++ Y+
Sbjct: 54 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113
Query: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPG 190
+ SSTYR V V YTQG W G +G DLV+IP G N + NIA I ES+ FF+ G
Sbjct: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFING 173
Query: 191 IKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGS---GTNGG 247
W GILGLAYA +A+ +CGAG P+ S + GG
Sbjct: 174 SNWEGILGLAYAEIAR-------------------------LCGAGFPLNQSEVLASVGG 208
Query: 248 SLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTT 307
S+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L +DC+EYN DK+IVDSGTT
Sbjct: 209 SMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTT 268
Query: 308 LLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENS 367
LRLP+KVF+A V+++ AS +F DGFW G QL CW TPW+ FP IS+YL E +
Sbjct: 269 NLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVT 328
Query: 368 SRSFRITILPQLYIQPMMGAGLNY-ECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRV 426
++SFRITILPQ Y++P+ + +CY+F IS S+ V+GA +MEGFYV+FDRA+KR+
Sbjct: 329 NQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRI 388
Query: 427 GFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVL 486
GFA S C + + GPF T D+ E L ++Y + ++C A+ ++
Sbjct: 389 GFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAIC-ALFMLP 447
Query: 487 IVLLLLPFRCQR--RPRDPEVVNDESSL 512
+ L++ +RC R R + + +D S L
Sbjct: 448 LCLMVCQWRCLRCLRQQHDDFADDISLL 475
>gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprotein
[Homo sapiens]
Length = 457
Score = 385 bits (988), Expect = e-107
Identities = 198/448 (44%), Positives = 272/448 (60%), Gaps = 51/448 (11%)
Query: 71 PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
P +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV PH ++ Y+
Sbjct: 54 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113
Query: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPG 190
+ SSTYR V V YTQG W G +G DL
Sbjct: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDL---------------------------- 145
Query: 191 IKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGS---GTNGG 247
P SLE FFDSLV Q ++PN+FS+Q+CGAG P+ S + GG
Sbjct: 146 ----------------PDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGG 189
Query: 248 SLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTT 307
S+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L +DC+EYN DK+IVDSGTT
Sbjct: 190 SMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTT 249
Query: 308 LLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENS 367
LRLP+KVF+A V+++ AS +F DGFW G QL CW TPW+ FP IS+YL E +
Sbjct: 250 NLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVT 309
Query: 368 SRSFRITILPQLYIQPMMGAGLNY-ECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRV 426
++SFRITILPQ Y++P+ + +CY+F IS S+ V+GA +MEGFYV+FDRA+KR+
Sbjct: 310 NQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRI 369
Query: 427 GFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVL 486
GFA S C + + GPF T D+ E L ++Y + ++C A+ ++
Sbjct: 370 GFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAIC-ALFMLP 428
Query: 487 IVLLLLPFRCQR--RPRDPEVVNDESSL 512
+ L++ +RC R R + + +D S L
Sbjct: 429 LCLMVCQWRCLRCLRQQHDDFADDISLL 456
>gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprotein
[Homo sapiens]
Length = 432
Score = 267 bits (683), Expect = 2e-71
Identities = 131/287 (45%), Positives = 189/287 (65%), Gaps = 7/287 (2%)
Query: 232 MCGAGLPVAGS---GTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSL 288
+CGAG P+ S + GGS+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L
Sbjct: 146 LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDL 205
Query: 289 NLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNS 348
+DC+EYN DK+IVDSGTT LRLP+KVF+A V+++ AS +F DGFW G QL CW
Sbjct: 206 KMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAG 265
Query: 349 ETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNY-ECYRFGISPSTNALVI 407
TPW+ FP IS+YL E +++SFRITILPQ Y++P+ + +CY+F IS S+ V+
Sbjct: 266 TTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVM 325
Query: 408 GATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPI 467
GA +MEGFYV+FDRA+KR+GFA S C + + GPF T D+ E
Sbjct: 326 GAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST 385
Query: 468 LWIVSYALMSVCGAILLVLIVLLLLPFRCQR--RPRDPEVVNDESSL 512
L ++Y + ++C A+ ++ + L++ +RC R R + + +D S L
Sbjct: 386 LMTIAYVMAAIC-ALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLL 431
Score = 109 bits (273), Expect = 5e-24
Identities = 51/93 (54%), Positives = 64/93 (68%)
Query: 71 PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
P +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV PH ++ Y+
Sbjct: 54 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113
Query: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLV 163
+ SSTYR V V YTQG W G +G DL+
Sbjct: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLL 146
>gi|4505757 progastricsin (pepsinogen C) [Homo sapiens]
Length = 388
Score = 119 bits (297), Expect = 9e-27
Identities = 84/240 (35%), Positives = 131/240 (54%), Gaps = 26/240 (10%)
Query: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV--------AGTPHSYIDTYFDTERSSTYRSKGF 143
Y+ E+ IGTPPQ +L DTGSSN V A T HS F+ SSTY + G
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSR----FNPSESSTYSTNGQ 128
Query: 144 DVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYAT 203
+++Y GS TGF G D +T+ + ++ NF +++GI+GLAY
Sbjct: 129 TFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYA--QFDGIMGLAYPA 186
Query: 204 LAKPSSSLETFFDSLVTQANIPN-VFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGD 262
L+ ++ T +V + + + VFS+ + G++GG++V GG++ SLY G
Sbjct: 187 LSVDEAT--TAMQGMVQEGALTSPVFSVYLSNQ------QGSSGGAVVFGGVDSSLYTGQ 238
Query: 263 IWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEA 322
I++ P+ +E Y+QI I + IGGQ+ C E +AIVD+GT+LL +PQ+ A+++A
Sbjct: 239 IYWAPVTQELYWQIGIEEFLIGGQASGW-CSE--GCQAIVDTGTSLLTVPQQYMSALLQA 295
>gi|4506475 renin preproprotein [Homo sapiens]
Length = 406
Score = 104 bits (259), Expect = 2e-22
Identities = 87/346 (25%), Positives = 165/346 (47%), Gaps = 36/346 (10%)
Query: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDT------YFDTERSSTYRSKGFDV 145
YY E+ IGTPPQ +++ DTGSSN V + S + T FD SS+Y+ G ++
Sbjct: 86 YYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTEL 145
Query: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
T++Y+ G+ +GF+ +D++T+ G + + T + F L +++G++G+ + +
Sbjct: 146 TLRYSTGTVSGFLSQDIITV-GGITVTQMFGEVTEMPALPFML--AEFDGVVGMGF--IE 200
Query: 206 KPSSSLETFFDSLVTQANI-PNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIW 264
+ + FD++++Q + +VFS S + GG +VLGG +P Y+G+
Sbjct: 201 QAIGRVTPIFDNIISQGVLKEDVFSFYY---NRDSENSQSLGGQIVLGGSDPQHYEGNFH 257
Query: 265 YTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVA 324
Y + + +QI++ + +G +L + + A+VD+G + + + ++EA+
Sbjct: 258 YINLIKTGVWQIQMKGVSVGSSTLLCE----DGCLALVDTGASYISGSTSSIEKLMEALG 313
Query: 325 RASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPM 384
+ ++ + C +E P P IS +L + + + + + Y
Sbjct: 314 AKKRLFDY--------VVKC---NEGP--TLPDISFHLGGKEYTLTSADYVFQESYSSKK 360
Query: 385 MGAGLNYECYRFGISPSTN-ALVIGATVMEGFYVIFDRAQKRVGFA 429
+ + I P T +GAT + FY FDR R+GFA
Sbjct: 361 L---CTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFA 403
>gi|4503143 cathepsin D preproprotein [Homo sapiens]
Length = 412
Score = 103 bits (258), Expect = 3e-22
Identities = 102/358 (28%), Positives = 166/358 (46%), Gaps = 49/358 (13%)
Query: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTY------FDTERSSTYRSKGFDV 145
YY E+ IGTPPQ ++ DTGSSN V +D +++++SSTY G
Sbjct: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSF 138
Query: 146 TVKYTQGSWTGFVGEDLVTIP--KGFNTSFL--VNIATIFESENFFLPGI-----KWNGI 196
+ Y GS +G++ +D V++P + S L V + E PGI K++GI
Sbjct: 139 DIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGI 198
Query: 197 LGLAYATLAKPSSSLETFFDSLVTQANIP-NVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
LG+AY ++ +++ FD+L+ Q + N+FS L GG L+LGG +
Sbjct: 199 LGMAYPRISV--NNVLPVFDNLMQQKLVDQNIFSFY-----LSRDPDAQPGGELMLGGTD 251
Query: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKV 315
YKG + Y + + Y+Q+ + ++E+ L L C+E +AIVD+GT+L+ P
Sbjct: 252 SKYYKGSLSYLNVTRKAYWQVHLDQVEVAS-GLTL-CKE--GCEAIVDTGTSLMVGP--- 304
Query: 316 FDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITI 375
D V E +P + + S P I++ L + ++++
Sbjct: 305 VDEVRELQKAIGAVPLIQGEYMIPCEKV---------STLPAITLKL----GGKGYKLS- 350
Query: 376 LPQLYIQPMMGAGLNYECYRF---GISPSTNAL-VIGATVMEGFYVIFDRAQKRVGFA 429
P+ Y + AG F I P + L ++G + +Y +FDR RVGFA
Sbjct: 351 -PEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFA 407
>gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens]
Length = 396
Score = 100 bits (250), Expect = 2e-21
Identities = 89/344 (25%), Positives = 155/344 (45%), Gaps = 35/344 (10%)
Query: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAG----TPHSYIDTYFDTERSSTYRSKGFDVTV 147
Y+ + IG+PPQ ++ DTGSSN V +P + F +SSTY G ++
Sbjct: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKP 207
+Y GS +G +G D V++ +G ++ E F+ +++GILGL Y +LA
Sbjct: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVDA-EFDGILGLGYPSLAV- 194
Query: 208 SSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTP 267
+ FD+++ Q N+ + M + G G L+ GG + S + G + + P
Sbjct: 195 -GGVTPVFDNMMAQ----NLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249
Query: 268 IKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARAS 327
+ ++ Y+QI + +++GG + C E +AIVD+GT+L+ P + A+ A
Sbjct: 250 VTKQAYWQIALDNIQVGGTV--MFCSE--GCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305
Query: 328 LIPEFSDGFWTGSQL--ACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMM 385
+ E++ + + +T + P++ P + L D F + L I P
Sbjct: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSP-TAYTLLDFVDGMQFCSSGFQGLDIHP-- 362
Query: 386 GAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFA 429
P+ ++G + FY +FDR RVG A
Sbjct: 363 --------------PAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392
>gi|119372302 pepsinogen 4, group I [Homo sapiens]
Length = 388
Score = 100 bits (249), Expect = 3e-21
Identities = 96/350 (27%), Positives = 161/350 (46%), Gaps = 52/350 (14%)
Query: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYI----DTYFDTERSSTYRSKGFDVTV 147
Y+ + IGTP Q ++ DTGSSN V S + F+ E SSTY+S V++
Sbjct: 76 YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135
Query: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESE-NFFLPGIKWNGILGLAYATLAK 206
Y GS TG +G D V + +T+ + ++ E+E FL ++GILGLAY +++
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLS---ETEPGSFLYYAPFDGILGLAYPSIS- 191
Query: 207 PSSSLETFFDSLVTQANIP-NVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWY 265
SS FD++ Q + ++FS+ + + +G ++ GGI+ S Y G + +
Sbjct: 192 -SSGATPVFDNIWNQGLVSQDLFSVYL-------SADDQSGSVVIFGGIDSSYYTGSLNW 243
Query: 266 TPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVAR 325
P+ E Y+QI + + + G++ + C E +AIVD+GT+LL P + +
Sbjct: 244 VPVTVEGYWQITVDSITMNGEA--IACAE--GCQAIVDTGTSLLTGPTSPIANIQSDIGA 299
Query: 326 ASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMM 385
+ E SDG ++C S P F + + + P YI
Sbjct: 300 S----ENSDG---DMVVSCSAISSLPDIVF-----------TINGVQYPVPPSAYILQSE 341
Query: 386 GA------GLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFA 429
G+ G+N + S ++G + ++ +FDRA +VG A
Sbjct: 342 GSCISGFQGMNLP------TESGELWILGDVFIRQYFTVFDRANNQVGLA 385
>gi|119372298 pepsinogen 3, group I [Homo sapiens]
Length = 388
Score = 100 bits (249), Expect = 3e-21
Identities = 96/350 (27%), Positives = 161/350 (46%), Gaps = 52/350 (14%)
Query: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYI----DTYFDTERSSTYRSKGFDVTV 147
Y+ + IGTP Q ++ DTGSSN V S + F+ E SSTY+S V++
Sbjct: 76 YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135
Query: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESE-NFFLPGIKWNGILGLAYATLAK 206
Y GS TG +G D V + +T+ + ++ E+E FL ++GILGLAY +++
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLS---ETEPGSFLYYAPFDGILGLAYPSIS- 191
Query: 207 PSSSLETFFDSLVTQANIP-NVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWY 265
SS FD++ Q + ++FS+ + + +G ++ GGI+ S Y G + +
Sbjct: 192 -SSGATPVFDNIWNQGLVSQDLFSVYL-------SADDQSGSVVIFGGIDSSYYTGSLNW 243
Query: 266 TPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVAR 325
P+ E Y+QI + + + G++ + C E +AIVD+GT+LL P + +
Sbjct: 244 VPVTVEGYWQITVDSITMNGEA--IACAE--GCQAIVDTGTSLLTGPTSPIANIQSDIGA 299
Query: 326 ASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMM 385
+ E SDG ++C S P F + + + P YI
Sbjct: 300 S----ENSDG---DMVVSCSAISSLPDIVF-----------TINGVQYPVPPSAYILQSE 341
Query: 386 GA------GLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFA 429
G+ G+N + S ++G + ++ +FDRA +VG A
Sbjct: 342 GSCISGFQGMNLP------TESGELWILGDVFIRQYFTVFDRANNQVGLA 385
>gi|23943854 pepsinogen 5, group I [Homo sapiens]
Length = 388
Score = 100 bits (249), Expect = 3e-21
Identities = 94/344 (27%), Positives = 160/344 (46%), Gaps = 40/344 (11%)
Query: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYI----DTYFDTERSSTYRSKGFDVTV 147
Y+ + IGTP Q ++ DTGSSN V S + F+ E SSTY+S V++
Sbjct: 76 YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135
Query: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESE-NFFLPGIKWNGILGLAYATLAK 206
Y GS TG +G D V + +T+ + ++ E+E FL ++GILGLAY +++
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLS---ETEPGSFLYYAPFDGILGLAYPSIS- 191
Query: 207 PSSSLETFFDSLVTQANIP-NVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWY 265
SS FD++ Q + ++FS+ + + +G ++ GGI+ S Y G + +
Sbjct: 192 -SSGATPVFDNIWNQGLVSQDLFSVYL-------SADDKSGSVVIFGGIDSSYYTGSLNW 243
Query: 266 TPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVAR 325
P+ E Y+QI + + + G++ + C E +AIVD+GT+LL P + +
Sbjct: 244 VPVTVEGYWQITVDSITMNGET--IACAE--GCQAIVDTGTSLLTGPTSPIANIQSDIGA 299
Query: 326 ASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMM 385
+ E SDG ++C S P F + + + P YI
Sbjct: 300 S----ENSDG---DMVVSCSAISSLPDIVF-----------TINGVQYPVPPSAYILQSE 341
Query: 386 GAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFA 429
G+ ++ + S ++G + ++ +FDRA +VG A
Sbjct: 342 GSCISGFQGMNVPTESGELWILGDVFIRQYFTVFDRANNQVGLA 385
>gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens]
Length = 363
Score = 79.3 bits (194), Expect = 8e-15
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 12/191 (6%)
Query: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAG----TPHSYIDTYFDTERSSTYRSKGFDVTV 147
Y+ + IG+PPQ ++ DTGSSN V +P + F +SSTY G ++
Sbjct: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKP 207
+Y GS +G +G D V++ +G ++ E F+ +++GILGL Y +LA
Sbjct: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVDA-EFDGILGLGYPSLA-- 193
Query: 208 SSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTP 267
+ FD+++ Q N+ + M + G G L+ GG + S + G + + P
Sbjct: 194 VGGVTPVFDNMMAQ----NLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249
Query: 268 IKEEWYYQIEI 278
+ ++ Y+QI +
Sbjct: 250 VTKQAYWQIAL 260
>gi|4758754 napsin A preproprotein [Homo sapiens]
Length = 420
Score = 77.0 bits (188), Expect = 4e-14
Identities = 71/246 (28%), Positives = 120/246 (48%), Gaps = 22/246 (8%)
Query: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAG------TPHSYIDTYFDTERSSTYRSKGFDV 145
Y+ E+ +GTPPQ + DTGSSN V + ++ FD + SS++++ G
Sbjct: 78 YFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKF 137
Query: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
++Y G G + ED +TI G + ++ ++E F ++GILGL + L+
Sbjct: 138 AIQYGTGRVDGILSEDKLTIG-GIKGASVIFGEALWEPSLVFAFA-HFDGILGLGFPILS 195
Query: 206 KPSSSLETFFDSLVTQANIPN-VFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIW 264
+ D LV Q + VFS L +GG LVLGG +P+ Y +
Sbjct: 196 V--EGVRPPMDVLVEQGLLDKPVFSFY-----LNRDPEEPDGGELVLGGSDPAHYIPPLT 248
Query: 265 YTPIKEEWYYQIEILKLEIG-GQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAV 323
+ P+ Y+QI + ++++G G +L C + A AI+D+GT+L+ P + A+ A+
Sbjct: 249 FVPVTVPAYWQIHMERVKVGPGLTL---CAKGCA--AILDTGTSLITGPTEEIRALHAAI 303
Query: 324 ARASLI 329
L+
Sbjct: 304 GGIPLL 309
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 33.9 bits (76), Expect = 0.37
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 10/76 (13%)
Query: 445 SGPFSTEDVASNCVPAQSLSEP-ILWIVSYALMSVCGAILLVLIVLLLLPFRCQR----R 499
S P+S E V PAQ EP +LW+ V IL++LIV+ +L F+ +R
Sbjct: 1239 SSPYSDEIVVQ-VTPAQQQEEPEMLWVTG----PVLAVILIILIVIAILLFKRKRTHSPS 1293
Query: 500 PRDPEVVNDESSLVRH 515
+D + + + SL+ H
Sbjct: 1294 SKDEQSIGLKDSLLAH 1309
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 33.9 bits (76), Expect = 0.37
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 10/76 (13%)
Query: 445 SGPFSTEDVASNCVPAQSLSEP-ILWIVSYALMSVCGAILLVLIVLLLLPFRCQR----R 499
S P+S E V PAQ EP +LW+ V IL++LIV+ +L F+ +R
Sbjct: 1230 SSPYSDEIVVQ-VTPAQQQEEPEMLWVTG----PVLAVILIILIVIAILLFKRKRTHSPS 1284
Query: 500 PRDPEVVNDESSLVRH 515
+D + + + SL+ H
Sbjct: 1285 SKDEQSIGLKDSLLAH 1300
>gi|39995080 hypothetical protein LOC79567 [Homo sapiens]
Length = 1219
Score = 33.1 bits (74), Expect = 0.63
Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 11/81 (13%)
Query: 22 PELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHAD-GLALALEPALASPAGAANFLAM 80
P +PAP + +T + ++PTP P TPA +H+D LA+A++ + + AG + ++
Sbjct: 736 PLTSPAPDP-----SESTVQSLSPTPSPPTPAPQHSDLCLAMAVQTPVPTAAGGSGDRSL 790
Query: 81 VDNLQG-----DSGRGYYLEM 96
+ L D RG + E+
Sbjct: 791 EEALGALMAALDDYRGQFPEL 811
>gi|197927448 WD repeat domain 6 protein [Homo sapiens]
Length = 1151
Score = 33.1 bits (74), Expect = 0.63
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 17/102 (16%)
Query: 225 PNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE-----PSLY----------KGDIWYTPIK 269
P V GAG PV GSG++GG G+ PSL+ G YT +
Sbjct: 558 PGVGGKARAGAGAPVVGSGSSGGGNAFTGLGPVSTLPSLHGKQGVTSVTCHGGYVYTTGR 617
Query: 270 EEWYYQIEILKLEIGGQSLNLDCREYN--ADKAIVDSGTTLL 309
+ YYQ+ + ++ CR N A IV G+ ++
Sbjct: 618 DGAYYQLFVRDGQLQPVLRQKSCRGMNWLAGLRIVPDGSMVI 659
>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
Length = 1338
Score = 32.7 bits (73), Expect = 0.82
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 12/89 (13%)
Query: 21 APELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGLALALEPALASPAGAANFLAM 80
+PE + LP R +A+ + + P P P P E + L A A A GAA+
Sbjct: 1007 SPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYR--LPPASAVATAQGPGAAS---- 1060
Query: 81 VDNLQGDSG-RGYYLEMLIG---TPPQKL 105
+L D+G G Y EM G TPPQ +
Sbjct: 1061 --SLSSDTGDNGDYTEMAFGVAATPPQPI 1087
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 32.7 bits (73), Expect = 0.82
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 2/40 (5%)
Query: 46 TPGPGTPAERHADGLALALEPALASP--AGAANFLAMVDN 83
TPGPGT + G+A A PA SP +G F + + N
Sbjct: 43 TPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSN 82
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 32.7 bits (73), Expect = 0.82
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 2/40 (5%)
Query: 46 TPGPGTPAERHADGLALALEPALASP--AGAANFLAMVDN 83
TPGPGT + G+A A PA SP +G F + + N
Sbjct: 43 TPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSN 82
>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
Length = 4302
Score = 32.3 bits (72), Expect = 1.1
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 117 AVAGTPHSYIDTY-FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLV 175
A A P Y T+ F TE ++ R++G +VT Y G LVT+ N S
Sbjct: 1402 ACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDP------GSYLVTVTASNNISAAN 1455
Query: 176 NIATIFESENFFLPGIKWNGILGL 199
+ A + E + IK NG LGL
Sbjct: 1456 DSALVEVQEPVLVTSIKVNGSLGL 1479
>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
Length = 4303
Score = 32.3 bits (72), Expect = 1.1
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 117 AVAGTPHSYIDTY-FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLV 175
A A P Y T+ F TE ++ R++G +VT Y G LVT+ N S
Sbjct: 1402 ACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDP------GSYLVTVTASNNISAAN 1455
Query: 176 NIATIFESENFFLPGIKWNGILGL 199
+ A + E + IK NG LGL
Sbjct: 1456 DSALVEVQEPVLVTSIKVNGSLGL 1479
>gi|239753114 PREDICTED: hypothetical protein [Homo sapiens]
Length = 322
Score = 32.0 bits (71), Expect = 1.4
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 5/45 (11%)
Query: 11 PLLAQWLLRAAPELA-----PAPFTLPLRVAAATNRVVAPTPGPG 50
PL+A ++AP L PAP L LR A+ + AP+PG G
Sbjct: 204 PLIAPGAHQSAPPLPVLGRLPAPLPLQLRAGGASTGLAAPSPGRG 248
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 32.0 bits (71), Expect = 1.4
Identities = 24/60 (40%), Positives = 26/60 (43%), Gaps = 9/60 (15%)
Query: 21 APELAPAPFTLPLRVAAATNRVVAPTPGPGTPAER-------HADGLALALEPALASPAG 73
AP A AP P AAA P+PGP P R A A A PA+A PAG
Sbjct: 138 APVAAAAPARAPRAAAAAA--TAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAG 195
>gi|124378039 SEC16 homolog A [Homo sapiens]
Length = 2357
Score = 31.2 bits (69), Expect = 2.4
Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 3/71 (4%)
Query: 19 RAAPELAPAPFTLPLRVAAATNRVVAPTPG---PGTPAERHADGLALALEPALASPAGAA 75
R+ P LAPA F PL + + PTP P P +G A A A PA
Sbjct: 2204 RSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEP 2263
Query: 76 NFLAMVDNLQG 86
L+ +L G
Sbjct: 2264 KVLSSAASLPG 2274
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 31.2 bits (69), Expect = 2.4
Identities = 26/71 (36%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Query: 21 APELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHAD-GLALALEPALASPAG-AANFL 78
APE P T P A VV TP P PAE D G +L P ++ P G A + L
Sbjct: 209 APEDPSGPGTGPSGTCEAPVAVVTVTPAP-EPAENSQDLGSTSSLGPGISGPRGQAPDTL 267
Query: 79 AMVDNLQGDSG 89
+ +D++ SG
Sbjct: 268 SYLDSVSLMSG 278
>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 30.0 bits (66), Expect = 5.3
Identities = 25/60 (41%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 17 LLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPG-TPAERHADGLALALEPALA-SPAGA 74
+L AP APAP P+ A V+AP P P PA A A A PA A +PA A
Sbjct: 142 VLAPAPAPAPAPVAAPVAAPVAV-AVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 200
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,321,740
Number of Sequences: 37866
Number of extensions: 986269
Number of successful extensions: 2859
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 2757
Number of HSP's gapped (non-prelim): 84
length of query: 518
length of database: 18,247,518
effective HSP length: 107
effective length of query: 411
effective length of database: 14,195,856
effective search space: 5834496816
effective search space used: 5834496816
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.