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Search of human proteins with 19923195
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923195 carcinoembryonic antigen-related cell adhesion
molecule 1 isoform 1 precursor [Homo sapiens]
(526 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923195 carcinoembryonic antigen-related cell adhesion molec... 1071 0.0
gi|68161541 carcinoembryonic antigen-related cell adhesion molec... 935 0.0
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 619 e-177
gi|40255013 carcinoembryonic antigen-related cell adhesion molec... 559 e-159
gi|21314600 carcinoembryonic antigen-related cell adhesion molec... 529 e-150
gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo sapi... 368 e-102
gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo sapi... 368 e-102
gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo sapi... 363 e-100
gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2 [... 361 e-100
gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1... 356 3e-98
gi|5901930 carcinoembryonic antigen-related cell adhesion molecu... 341 1e-93
gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b ... 298 1e-80
gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a [... 298 1e-80
gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor ... 296 4e-80
gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo sapi... 293 3e-79
gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens] 289 4e-78
gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1 [... 284 1e-76
gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo sapi... 284 1e-76
gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [H... 282 5e-76
gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b [... 278 9e-75
gi|121114300 carcinoembryonic antigen-related cell adhesion mole... 244 1e-64
gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c ... 230 3e-60
gi|52317156 carcinoembryonic antigen-related cell adhesion molec... 225 7e-59
gi|148612793 carcinoembryonic antigen-related cell adhesion mole... 223 3e-58
gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2... 214 1e-55
gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2... 214 1e-55
gi|156564390 carcinoembryonic antigen-related cell adhesion mole... 197 3e-50
gi|156564388 carcinoembryonic antigen-related cell adhesion mole... 197 3e-50
gi|85861202 carcinoembryonic antigen-related cell adhesion molec... 178 9e-45
gi|156564378 carcinoembryonic antigen-related cell adhesion mole... 167 3e-41
>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 1 precursor [Homo sapiens]
Length = 526
Score = 1072 bits (2771), Expect = 0.0
Identities = 526/526 (100%), Positives = 526/526 (100%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ
Sbjct: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY
Sbjct: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
Query: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 180
TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI
Sbjct: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 180
Query: 181 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 240
NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP
Sbjct: 181 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 240
Query: 241 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 300
TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH
Sbjct: 241 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 300
Query: 301 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF 360
ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF
Sbjct: 301 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF 360
Query: 361 FKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALP 420
FKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALP
Sbjct: 361 FKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALP 420
Query: 421 QENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRASDQRDLTEHKPSVSNHTQDH 480
QENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRASDQRDLTEHKPSVSNHTQDH
Sbjct: 421 QENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRASDQRDLTEHKPSVSNHTQDH 480
Query: 481 SNDPPNKMNEVTYSTLNFEAQQPTQPTSASPSLTATEIIYSEVKKQ 526
SNDPPNKMNEVTYSTLNFEAQQPTQPTSASPSLTATEIIYSEVKKQ
Sbjct: 481 SNDPPNKMNEVTYSTLNFEAQQPTQPTSASPSLTATEIIYSEVKKQ 526
>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 2 precursor [Homo sapiens]
Length = 464
Score = 935 bits (2417), Expect = 0.0
Identities = 458/458 (100%), Positives = 458/458 (100%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ
Sbjct: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY
Sbjct: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
Query: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 180
TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI
Sbjct: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 180
Query: 181 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 240
NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP
Sbjct: 181 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 240
Query: 241 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 300
TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH
Sbjct: 241 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 300
Query: 301 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF 360
ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF
Sbjct: 301 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF 360
Query: 361 FKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALP 420
FKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALP
Sbjct: 361 FKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALP 420
Query: 421 QENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTG 458
QENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTG
Sbjct: 421 QENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTG 458
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 619 bits (1596), Expect = e-177
Identities = 309/423 (73%), Positives = 339/423 (80%), Gaps = 5/423 (1%)
Query: 5 SAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQQLFG 64
SAP HR +PWQ LLLTASLLTFWNPPTTA+LT ES PFNVAEGKEVLLLVHNLPQ LFG
Sbjct: 5 SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
Query: 65 YSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQV 124
YSWYKGERVDGNRQI+GY IGTQQATPGPA SGRE IYPNASLLIQN+ QNDTGFYTL V
Sbjct: 65 YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
Query: 125 IKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQS 184
IKSDLVNEEATGQF VYPELPKPSISSNNS PVEDKDAVAFTCEPETQD TYLWW+NNQS
Sbjct: 125 IKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQS 184
Query: 185 LPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISP 244
LPVSPRLQLSNGNRTLTL +VTRNDT Y+CE QNPVSA RSD V LNV YGPD PTISP
Sbjct: 185 LPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISP 244
Query: 245 SDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNS 304
+T YR G NL+LSC+AASNPPAQYSW +NGTFQQSTQELFIPNITVNNSGSYTC A+NS
Sbjct: 245 LNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAHNS 304
Query: 305 VTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQ 364
TG NRTTV TI V P KP I ++ + D+D+V LTC + W+ NQ
Sbjct: 305 DTGLNRTTVTTITVYAEPP---KPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQ 361
Query: 365 SLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENG 424
SLP S R++LS N TL++ V R D G Y C + N +S + SDP++LNV Y P +
Sbjct: 362 SLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYG--PDDPT 419
Query: 425 LSP 427
+SP
Sbjct: 420 ISP 422
Score = 376 bits (966), Expect = e-104
Identities = 192/311 (61%), Positives = 222/311 (71%), Gaps = 4/311 (1%)
Query: 107 LLIQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAF 165
L I N+T N++G YT Q SD +N VY E PKP I+SNNSNPVED+DAVA
Sbjct: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVAL 343
Query: 166 TCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANR 225
TCEPE Q+TTYLWW+NNQSLPVSPRLQLSN NRTLTLLSVTRND GPYEC IQN +S +
Sbjct: 344 TCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDH 403
Query: 226 SDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELF 285
SDPV LNV YGPD PTISPS TYYRPG NLSLSC+AASNPPAQYSWLI+G QQ TQELF
Sbjct: 404 SDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELF 463
Query: 286 IPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVN 345
I NIT NSG YTC ANNS +G +RTTVKTI V+ P KP I ++ + DKD+V
Sbjct: 464 ISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELP---KPSISSNNSKPVEDKDAVA 520
Query: 346 LTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKN 405
TC + W+ QSLP S R++LS GN TL++ V R DA Y C + N +S N
Sbjct: 521 FTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSAN 580
Query: 406 QSDPIMLNVNY 416
+SDP+ L+V Y
Sbjct: 581 RSDPVTLDVLY 591
Score = 275 bits (703), Expect = 7e-74
Identities = 139/214 (64%), Positives = 159/214 (74%), Gaps = 1/214 (0%)
Query: 107 LLIQNVTQNDTGFYTLQVIKSDLVNEEATGQ-FHVYPELPKPSISSNNSNPVEDKDAVAF 165
L I N+T+ ++G YT Q S + T + V ELPKPSISSNNS PVEDKDAVAF
Sbjct: 462 LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAF 521
Query: 166 TCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANR 225
TCEPE Q+TTYLWW+N QSLPVSPRLQLSNGNRTLTL +VTRND Y C IQN VSANR
Sbjct: 522 TCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANR 581
Query: 226 SDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELF 285
SDPVTL+V YGPDTP ISP D+ Y GANL+LSC++ASNP QYSW ING QQ TQ LF
Sbjct: 582 SDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLF 641
Query: 286 IPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVT 319
I IT NN+G+Y C +N TG N + VK+I V+
Sbjct: 642 IAKITPNNNGTYACFVSNLATGRNNSIVKSITVS 675
Score = 69.7 bits (169), Expect = 6e-12
Identities = 87/358 (24%), Positives = 152/358 (42%), Gaps = 47/358 (13%)
Query: 104 NASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVY--PELPKPSISSNNSNPVEDKD 161
N +L + +VT+ND G Y + V+ +V P+ P S S P +
Sbjct: 375 NRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVN-- 432
Query: 162 AVAFTCEPETQDTT-YLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNP 220
++ +C + Y W I+ + L +SN +T ++G Y C+ N
Sbjct: 433 -LSLSCHAASNPPAQYSWLIDGNIQQHTQELFISN---------ITEKNSGLYTCQANNS 482
Query: 221 VSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQ---YSWLINGT- 276
S + V +T + P S S +P + + P AQ Y W +NG
Sbjct: 483 ASGHSRTTVK-TITVSAELPKPSISSNNSKPVEDKDAVAFTCE-PEAQNTTYLWWVNGQS 540
Query: 277 --------FQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVT--ELSPVVA 326
+ L + N+T N++ +Y C NSV+ NR+ T+ V +P+++
Sbjct: 541 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSA-NRSDPVTLDVLYGPDTPIIS 599
Query: 327 KPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPV 386
P + ++G ++NL+C + S ++ ++ +P Q L I +
Sbjct: 600 PPD----SSYLSGA--NLNLSCHSASNP-SPQYSWRINGIPQ-------QHTQVLFIAKI 645
Query: 387 KREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALI 444
+ GTY C V N ++ +++ I+ ++ +A GLS GA GI+IGV+ VALI
Sbjct: 646 TPNNNGTYACFVSN-LATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 702
>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
6 (non-specific cross reacting antigen) [Homo sapiens]
Length = 344
Score = 559 bits (1441), Expect = e-159
Identities = 274/326 (84%), Positives = 287/326 (88%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG SAP R+ VPW+ +LLTASLLTFWNPPTTA+LT ES PFNVAEGKEVLLL HNLPQ
Sbjct: 1 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
GYSWYKGERVDGN IVGY IGTQQATPGPA SGRETIYPNASLLIQNVTQNDTGFY
Sbjct: 61 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY 120
Query: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 180
TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPE Q+TTYLWW+
Sbjct: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV 180
Query: 181 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 240
N QSLPVSPRLQLSNGN TLTLLSV RND G YECEIQNP SANRSDPVTLNV YGPD P
Sbjct: 181 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDGP 240
Query: 241 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 300
TISPS YRPG NL+LSC+AASNPPAQYSW INGTFQQSTQELFIPNITVNNSGSY C
Sbjct: 241 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ 300
Query: 301 ANNSVTGCNRTTVKTIIVTELSPVVA 326
A+NS TG NRTTV I V+ +PV++
Sbjct: 301 AHNSATGLNRTTVTMITVSGSAPVLS 326
Score = 97.8 bits (242), Expect = 2e-20
Identities = 57/144 (39%), Positives = 77/144 (53%), Gaps = 6/144 (4%)
Query: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDS 343
L I N+T N++G YT S T + + EL KP I ++ + DKD+
Sbjct: 107 LLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELP----KPSISSNNSNPVEDKDA 162
Query: 344 VNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPIS 403
V TC + W+ QSLP S R++LS GN TL++ VKR DAG+Y CE+ NP S
Sbjct: 163 VAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPAS 222
Query: 404 KNQSDPIMLNVNYNALPQENGLSP 427
N+SDP+ LNV Y P +SP
Sbjct: 223 ANRSDPVTLNVLYG--PDGPTISP 244
Score = 53.5 bits (127), Expect = 5e-07
Identities = 68/262 (25%), Positives = 106/262 (40%), Gaps = 35/262 (13%)
Query: 197 NRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLS 256
N +L + +VT+NDTG Y ++ N +V P+ P S S P +
Sbjct: 104 NASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVY--PELPKPSISSNNSNPVEDKD 161
Query: 257 LSCYAASNPPAQ---YSWLINGTFQQSTQELFIPN---------ITVNNSGSYTCHANNS 304
+ P Q Y W +NG + L + N + N++GSY C N
Sbjct: 162 AVAFTCE-PEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNP 220
Query: 305 VTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTC-STNDTGISIRWFFKN 363
+ NR+ T+ V P P I SK +++NL+C + ++ WF
Sbjct: 221 ASA-NRSDPVTLNVL-YGP--DGPTISPSKANYRPG-ENLNLSCHAASNPPAQYSWFING 275
Query: 364 QSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISK-NQSDPIMLNVNYNALPQE 422
Q L I + ++G+Y C+ N + N++ M+ V+ +A
Sbjct: 276 T---------FQQSTQELFIPNITVNNSGSYMCQAHNSATGLNRTTVTMITVSGSAPV-- 324
Query: 423 NGLSPGAIAGIVIGVVALVALI 444
LS A GI IGV+A VALI
Sbjct: 325 --LSAVATVGITIGVLARVALI 344
>gi|21314600 carcinoembryonic antigen-related cell adhesion molecule
8 [Homo sapiens]
Length = 349
Score = 529 bits (1363), Expect = e-150
Identities = 255/335 (76%), Positives = 281/335 (83%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG +SAP R R+PWQGLLLTASL TFWNPPTTAQLT E++P N AEGKEVLLLVHNLPQ
Sbjct: 1 MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
GY+WYKGE VD NR+I+GY I QQ TPGPA S RETIYPNASLL++NVT+NDTG Y
Sbjct: 61 DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
Query: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 180
TLQVIK +L++EE TGQF V+PE PKPSISSNNSNPVEDKDAVAFTCEPETQ+TTYLWW+
Sbjct: 121 TLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWV 180
Query: 181 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 240
N QSLPVSPRLQLSNGNRTLTLLSVTRND GPYECEIQNP SAN SDPVTLNV YGPD P
Sbjct: 181 NGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAP 240
Query: 241 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 300
TISPSDTYY G NL+LSC+AASNPP+QYSW +NGTFQQ TQ+LFIPNIT NSGSY CH
Sbjct: 241 TISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACH 300
Query: 301 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKT 335
NS TG NRTTV+ I V++ + P + A T
Sbjct: 301 TTNSATGRNRTTVRMITVSDALVQGSSPGLSARAT 335
Score = 93.2 bits (230), Expect = 5e-19
Identities = 54/144 (37%), Positives = 74/144 (51%), Gaps = 6/144 (4%)
Query: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDS 343
L + N+T N++GSYT V N + + + P KP I ++ + DKD+
Sbjct: 107 LLMRNVTRNDTGSYTLQ----VIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDA 162
Query: 344 VNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPIS 403
V TC + W+ QSLP S R++LS GN TL++ V R D G Y CE+ NP S
Sbjct: 163 VAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPAS 222
Query: 404 KNQSDPIMLNVNYNALPQENGLSP 427
N SDP+ LNV Y P +SP
Sbjct: 223 ANFSDPVTLNVLYG--PDAPTISP 244
Score = 55.8 bits (133), Expect = 9e-08
Identities = 82/340 (24%), Positives = 133/340 (39%), Gaps = 58/340 (17%)
Query: 142 PELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWW---------------INNQSLP 186
P + +I + SN E K+ + Y W+ I+NQ +
Sbjct: 31 PTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYKGETVDANRRIIGYVISNQQIT 90
Query: 187 VSPRL---QLSNGNRTLTLLSVTRNDTGPYECEIQNPVSAN-RSDPVTLNVTYGPDTPTI 242
P + N +L + +VTRNDTG Y ++ + N S+ VT + P+TP
Sbjct: 91 PGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQV---IKLNLMSEEVTGQFSVHPETPKP 147
Query: 243 SPSDTYYRPGANLSLSCYAASNPPAQ---YSWLINGT---------FQQSTQELFIPNIT 290
S S P + + P Q Y W +NG + L + ++T
Sbjct: 148 SISSNNSNPVEDKDAVAFTCE-PETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVT 206
Query: 291 VNNSGSYTCHANN--SVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTC 348
N+ G Y C N S + T+ + + P I S T + +NL+C
Sbjct: 207 RNDVGPYECEIQNPASANFSDPVTLNVLYGPDA------PTISPSDTYYHAGVN-LNLSC 259
Query: 349 -STNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPIS-KNQ 406
+ ++ W S Q L I + +++G+Y C N + +N+
Sbjct: 260 HAASNPPSQYSW---------SVNGTFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNR 310
Query: 407 SDPIMLNVNYNALPQEN--GLSPGAIAGIVIGVVALVALI 444
+ M+ V+ +AL Q + GLS A I+IGV+A VALI
Sbjct: 311 TTVRMITVS-DALVQGSSPGLSARATVSIMIGVLARVALI 349
>gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo
sapiens]
Length = 335
Score = 368 bits (944), Expect = e-102
Identities = 188/330 (56%), Positives = 228/330 (69%), Gaps = 2/330 (0%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP + W+GLLLTASLL FWN P TAQ+T E++P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGPLSAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ +D I Y + Q GPA +GRET+Y NASLLIQNVT+ D G Y
Sbjct: 61 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY 120
Query: 121 TLQVIKSDLVNEEATGQF--HVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +IK TG F ++Y +LPKP I+ NNS P E+KD +AFTCEP++++ TY+W
Sbjct: 121 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLPVSPR++ NR L L SVTRN+TGPYECEI++ RSDPVTLNV YGPD
Sbjct: 181 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD 240
Query: 239 TPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYT 298
P+I PS TYYR G NL LSC+A SNPPA+Y W ING FQQS Q+L IP IT + G YT
Sbjct: 241 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT 300
Query: 299 CHANNSVTGCNRTTVKTIIVTELSPVVAKP 328
C NS TG + T+ V+ S + P
Sbjct: 301 CSVRNSATGKESSKSMTVEVSAPSGIGRLP 330
Score = 65.5 bits (158), Expect = 1e-10
Identities = 43/137 (31%), Positives = 60/137 (43%), Gaps = 2/137 (1%)
Query: 280 STQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTG 339
S L I N+T ++GSYT H G V L + KP I + +
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKR--GDRTRGVTGYFTFNLYLKLPKPYITINNSKPRE 160
Query: 340 DKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVF 399
+KD + TC + W+ QSLP S R+K N L + V R + G Y CE+
Sbjct: 161 NKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIR 220
Query: 400 NPISKNQSDPIMLNVNY 416
+ +SDP+ LNV Y
Sbjct: 221 DRDGGMRSDPVTLNVLY 237
Score = 34.3 bits (77), Expect = 0.29
Identities = 47/227 (20%), Positives = 79/227 (34%), Gaps = 26/227 (11%)
Query: 197 NRTLTLLSVTRNDTGPYECEIQNPVSANR--SDPVTLNVTYGPDTPTISPSDTYYRPGAN 254
N +L + +VTR D G Y I R + T N+ P I+ +++ R +
Sbjct: 104 NASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKD 163
Query: 255 LSLSCYAASNPPAQYSWLINGTFQQSTQE---------LFIPNITVNNSGSYTCHANNSV 305
+ + Y W +NG + L +P++T N +G Y C +
Sbjct: 164 VLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRD 223
Query: 306 TGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCST-NDTGISIRWFFKNQ 364
G V V+ P + + + T + NL S ++ +F+
Sbjct: 224 GGMRSDPVTL-------NVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTIN 276
Query: 365 SLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIM 411
K Q LSI + + G Y C V N + +S M
Sbjct: 277 G-------KFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSM 316
>gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo
sapiens]
Length = 335
Score = 368 bits (944), Expect = e-102
Identities = 188/330 (56%), Positives = 228/330 (69%), Gaps = 2/330 (0%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP + W+GLLLTASLL FWN P TAQ+T E++P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGPLSAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ +D I Y + Q GPA +GRET+Y NASLLIQNVT+ D G Y
Sbjct: 61 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY 120
Query: 121 TLQVIKSDLVNEEATGQF--HVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +IK TG F ++Y +LPKP I+ NNS P E+KD +AFTCEP++++ TY+W
Sbjct: 121 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLPVSPR++ NR L L SVTRN+TGPYECEI++ RSDPVTLNV YGPD
Sbjct: 181 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD 240
Query: 239 TPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYT 298
P+I PS TYYR G NL LSC+A SNPPA+Y W ING FQQS Q+L IP IT + G YT
Sbjct: 241 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT 300
Query: 299 CHANNSVTGCNRTTVKTIIVTELSPVVAKP 328
C NS TG + T+ V+ S + P
Sbjct: 301 CSVRNSATGKESSKSMTVEVSAPSGIGRLP 330
Score = 65.5 bits (158), Expect = 1e-10
Identities = 43/137 (31%), Positives = 60/137 (43%), Gaps = 2/137 (1%)
Query: 280 STQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTG 339
S L I N+T ++GSYT H G V L + KP I + +
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKR--GDRTRGVTGYFTFNLYLKLPKPYITINNSKPRE 160
Query: 340 DKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVF 399
+KD + TC + W+ QSLP S R+K N L + V R + G Y CE+
Sbjct: 161 NKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIR 220
Query: 400 NPISKNQSDPIMLNVNY 416
+ +SDP+ LNV Y
Sbjct: 221 DRDGGMRSDPVTLNVLY 237
Score = 34.3 bits (77), Expect = 0.29
Identities = 47/227 (20%), Positives = 79/227 (34%), Gaps = 26/227 (11%)
Query: 197 NRTLTLLSVTRNDTGPYECEIQNPVSANR--SDPVTLNVTYGPDTPTISPSDTYYRPGAN 254
N +L + +VTR D G Y I R + T N+ P I+ +++ R +
Sbjct: 104 NASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKD 163
Query: 255 LSLSCYAASNPPAQYSWLINGTFQQSTQE---------LFIPNITVNNSGSYTCHANNSV 305
+ + Y W +NG + L +P++T N +G Y C +
Sbjct: 164 VLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRD 223
Query: 306 TGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCST-NDTGISIRWFFKNQ 364
G V V+ P + + + T + NL S ++ +F+
Sbjct: 224 GGMRSDPVTL-------NVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTIN 276
Query: 365 SLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIM 411
K Q LSI + + G Y C V N + +S M
Sbjct: 277 G-------KFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSM 316
>gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo
sapiens]
Length = 335
Score = 363 bits (932), Expect = e-100
Identities = 189/321 (58%), Positives = 218/321 (67%), Gaps = 2/321 (0%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP + W+GLL+TASLL FWN PTTAQ+T E+ P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGPLSAPPCTEHIKWKGLLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ D I Y + Q GPA SGRET Y NASLLIQNVT+ D G Y
Sbjct: 61 NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 120
Query: 121 TLQVIKSDLVNEEATGQFH--VYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +IK TG F +Y E PKPSISS+N NP E + V TC+PET DT+Y W
Sbjct: 121 TLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCDPETPDTSYQW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLP++ R QLS NRTL L VT+ GPYECEI+N SA+RSDPVTLN+ +GPD
Sbjct: 181 WMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGPD 240
Query: 239 TPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYT 298
P I PS T YR G NL LSC+A SNPPAQYSW ING FQQS Q LFIP IT +SG Y
Sbjct: 241 LPRIHPSYTNYRSGDNLYLSCFANSNPPAQYSWTINGKFQQSGQNLFIPQITTKHSGLYV 300
Query: 299 CHANNSVTGCNRTTVKTIIVT 319
C NS TG +T T+ V+
Sbjct: 301 CSVRNSATGEESSTSLTVKVS 321
Score = 75.1 bits (183), Expect = 1e-13
Identities = 46/135 (34%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Query: 280 STQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTG 339
S L I N+T ++GSYT H G T L KP I +S
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLE--TPKPSISSSNLNPRE 160
Query: 340 DKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVF 399
++V LTC S +W+ QSLP + R +LS+ N TL + V + AG Y CE+
Sbjct: 161 AMETVILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIR 220
Query: 400 NPISKNQSDPIMLNV 414
N S ++SDP+ LN+
Sbjct: 221 NSGSASRSDPVTLNL 235
Score = 44.3 bits (103), Expect = 3e-04
Identities = 52/224 (23%), Positives = 79/224 (35%), Gaps = 28/224 (12%)
Query: 197 NRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLS 256
N +L + +VTR D G Y I R T +TP S S + P +
Sbjct: 104 NASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAME 163
Query: 257 ---LSCYAASNPPAQYSWLINGT---------FQQSTQELFIPNITVNNSGSYTCHANNS 304
L+C P Y W +NG ++ + LF+ +T +G Y C NS
Sbjct: 164 TVILTC-DPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNS 222
Query: 305 VTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTG-ISIRWFFKN 363
+ V ++ P + P+I S T D++ L+C N W
Sbjct: 223 GSASRSDPVTLNLLH--GPDL--PRIHPSYTNYRSG-DNLYLSCFANSNPPAQYSWTING 277
Query: 364 QSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQS 407
K Q L I + + +G Y C V N + +S
Sbjct: 278 ---------KFQQSGQNLFIPQITTKHSGLYVCSVRNSATGEES 312
>gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2
[Homo sapiens]
Length = 326
Score = 361 bits (927), Expect = e-100
Identities = 186/322 (57%), Positives = 221/322 (68%), Gaps = 2/322 (0%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP R+ W+G+LLTASLL FWNPPTTAQ+T E+ P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ I Y + Q+ GPA SGRE +Y NASLLIQNVTQ D G Y
Sbjct: 61 NLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSY 120
Query: 121 TLQVIKSDLVNEEATGQFH--VYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +IK TG F ++ E PKPSISS+N NP E +AV TC+P T +Y W
Sbjct: 121 TLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLP++ RLQLS NRTL + VT+ GPYECEI+NPVSA+RSDPVTLN+ +GPD
Sbjct: 181 WMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLHGPD 240
Query: 239 TPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYT 298
P+I PS TYYR G NL LSC+A SNP AQYSW ING FQ S Q+L IP IT +SG Y
Sbjct: 241 LPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLSGQKLSIPQITTKHSGLYA 300
Query: 299 CHANNSVTGCNRTTVKTIIVTE 320
C NS TG + T+ V++
Sbjct: 301 CSVRNSATGKESSKSITVKVSD 322
Score = 82.4 bits (202), Expect = 9e-16
Identities = 48/135 (35%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Query: 280 STQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTG 339
S L I N+T ++GSYT H G T L KP I +S
Sbjct: 103 SNASLLIQNVTQEDAGSYTLHIIKRRDGTGGVTGHFTFTLHLE--TPKPSISSSNLNPRE 160
Query: 340 DKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVF 399
++V LTC S +W+ QSLP + R++LS+ N TL I V + AG Y CE+
Sbjct: 161 AMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIR 220
Query: 400 NPISKNQSDPIMLNV 414
NP+S ++SDP+ LN+
Sbjct: 221 NPVSASRSDPVTLNL 235
>gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1
[Homo sapiens]
Length = 335
Score = 356 bits (913), Expect = 3e-98
Identities = 187/320 (58%), Positives = 215/320 (67%), Gaps = 2/320 (0%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP + W+GLLLTA LL FWN PTTAQ+ E+ P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGPLSAPPCTEHIKWKGLLLTALLLNFWNLPTTAQVMIEAQPPKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ D I Y + Q GPA SGRET+Y NASLLIQNVT+ D G Y
Sbjct: 61 NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSY 120
Query: 121 TLQVIKSDLVNEEATGQFH--VYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +IK TG F +Y E PKPSISS+N NP E + V TC PET D +YLW
Sbjct: 121 TLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCNPETPDASYLW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLP++ R+QLS NRTL L VT+ GPYECEI N SA+RSDPVTLN+ +GPD
Sbjct: 181 WMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPD 240
Query: 239 TPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYT 298
P I PS T Y G NL LSC+A SNPPAQYSW ING FQ S Q+LFIP IT ++G Y
Sbjct: 241 LPRIFPSVTSYYSGENLDLSCFANSNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYA 300
Query: 299 CHANNSVTGCNRTTVKTIIV 318
C A NS TG +T TI V
Sbjct: 301 CSARNSATGEESSTSLTIRV 320
Score = 77.8 bits (190), Expect = 2e-14
Identities = 47/135 (34%), Positives = 66/135 (48%), Gaps = 2/135 (1%)
Query: 280 STQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTG 339
S L I N+T ++GSYT H G T L KP I +S
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLE--TPKPSISSSNLNPRE 160
Query: 340 DKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVF 399
++V LTC+ S W+ QSLP + RM+LS+ N TL + V + AG Y CE++
Sbjct: 161 AMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIW 220
Query: 400 NPISKNQSDPIMLNV 414
N S ++SDP+ LN+
Sbjct: 221 NSGSASRSDPVTLNL 235
>gi|5901930 carcinoembryonic antigen-related cell adhesion molecule
7 [Homo sapiens]
Length = 265
Score = 341 bits (874), Expect = 1e-93
Identities = 166/236 (70%), Positives = 191/236 (80%), Gaps = 1/236 (0%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG SA +RV +PWQGLLLTASLLTFWN P +AQ + +PFNVAEGKEVLL+VHN Q
Sbjct: 1 MGSPSACPYRVCIPWQGLLLTASLLTFWNLPNSAQTNIDVVPFNVAEGKEVLLVVHNESQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIG-TQQATPGPANSGRETIYPNASLLIQNVTQNDTGF 119
L+GY+WYKGERV N +I+GY +Q+ PGPA++GRETIYPN +LLIQNVT ND GF
Sbjct: 61 NLYGYNWYKGERVHANYRIIGYVKNISQENAPGPAHNGRETIYPNGTLLIQNVTHNDAGF 120
Query: 120 YTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWW 179
YTL VIK +LVNEE T QF+V+ E PKPSI+SNN NPVE+KD V TC+PETQ+TTYLWW
Sbjct: 121 YTLHVIKENLVNEEVTRQFYVFSEPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYLWW 180
Query: 180 INNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTY 235
+NNQSL VSPRL LS NRTL LLS T+ND GPYECEIQNPV A+RSDPVTLNV Y
Sbjct: 181 VNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGASRSDPVTLNVRY 236
Score = 92.4 bits (228), Expect = 9e-19
Identities = 57/162 (35%), Positives = 82/162 (50%), Gaps = 5/162 (3%)
Query: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDS 343
L I N+T N++G YT H T + + +E KP I ++ +KD
Sbjct: 108 LLIQNVTHNDAGFYTLHVIKENLVNEEVTRQFYVFSE----PPKPSITSNNFNPVENKDI 163
Query: 344 VNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPIS 403
V LTC + W+ NQSL S R+ LS N TL + + D G Y CE+ NP+
Sbjct: 164 VVLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVG 223
Query: 404 KNQSDPIMLNVNYNALPQEN-GLSPGAIAGIVIGVVALVALI 444
++SDP+ LNV Y ++ + LS G I+IGV+A +ALI
Sbjct: 224 ASRSDPVTLNVRYESVQASSPDLSAGTAVSIMIGVLAGMALI 265
Score = 35.8 bits (81), Expect = 0.099
Identities = 36/147 (24%), Positives = 58/147 (39%), Gaps = 14/147 (9%)
Query: 197 NRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGAN-- 254
N TL + +VT ND G Y + N V P P+I+ ++ + P N
Sbjct: 105 NGTLLIQNVTHNDAGFYTLHVIKENLVNEEVTRQFYVFSEPPKPSITSNN--FNPVENKD 162
Query: 255 -LSLSCYAASNPPAQYSWLINGTFQQS--------TQELFIPNITVNNSGSYTCHANNSV 305
+ L+C + W+ N + S + L + + T N+ G Y C N V
Sbjct: 163 IVVLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPV 222
Query: 306 TGCNRTTVKTIIVTELSPVVAKPQIKA 332
G +R+ T+ V S + P + A
Sbjct: 223 -GASRSDPVTLNVRYESVQASSPDLSA 248
>gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b
[Homo sapiens]
Length = 419
Score = 298 bits (762), Expect = 1e-80
Identities = 184/426 (43%), Positives = 237/426 (55%), Gaps = 32/426 (7%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP R+ W+GLLLTASLL FWNPPTTAQ+T E+ P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGLLSAPPCTQRITWKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ D I Y + Q GPA SGRETIY NASLLIQNVTQ D G Y
Sbjct: 61 NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSY 120
Query: 121 TLQVIKSDLVNEEATGQ--FHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +I N TG F +Y E PKPSISS+ NP E +AV+ TC+PET D +YLW
Sbjct: 121 TLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLP+S RLQLS NRTL LL VT+ GPYECEI+NPVSA+RSDP TLN+
Sbjct: 181 WMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLP 240
Query: 239 TPTISPSDTYYRPGAN-LSLSCYAASNPPAQYSWLINGTFQQ---------STQELFIPN 288
P I+ ++ R + L+ +C S Y W +NG + L +P+
Sbjct: 241 KPYITINNLKPRENKDVLNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPS 299
Query: 289 ITVNNSGSYTCHANNSVTGCNR--TTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNL 346
+T N +G Y C + G T+ + +L P+I S T + + L
Sbjct: 300 VTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDL------PRIYPSFTYYRSG-EVLYL 352
Query: 347 TCST-NDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKN 405
+CS ++ W + S +++ + Q + + +G Y C V N +
Sbjct: 353 SCSADSNPPAQYSWTINGKFQLSGQKLFIPQ---------ITTKHSGLYACSVRNSATGK 403
Query: 406 QSDPIM 411
+S M
Sbjct: 404 ESSKSM 409
Score = 219 bits (558), Expect = 5e-57
Identities = 110/217 (50%), Positives = 140/217 (64%)
Query: 104 NASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAV 163
N +L + VT+ G Y ++ + ++ P+LPKP I+ NN P E+KD +
Sbjct: 199 NRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVL 258
Query: 164 AFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSA 223
FTCEP++++ TY+WW+N QSLPVSPR++ NR L L SVTRN+TGPY+CEI++
Sbjct: 259 NFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGG 318
Query: 224 NRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQE 283
RS PVTLNV YGPD P I PS TYYR G L LSC A SNPPAQYSW ING FQ S Q+
Sbjct: 319 IRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQK 378
Query: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTE 320
LFIP IT +SG Y C NS TG + T+ V++
Sbjct: 379 LFIPQITTKHSGLYACSVRNSATGKESSKSMTVKVSD 415
Score = 87.4 bits (215), Expect = 3e-17
Identities = 67/232 (28%), Positives = 99/232 (42%), Gaps = 17/232 (7%)
Query: 197 NRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANL- 255
N +L + +VT+ D G Y I NR T +TP S S + P +
Sbjct: 104 NASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAME 163
Query: 256 --SLSCYAASNPPAQYSWLINGT---------FQQSTQELFIPNITVNNSGSYTCHANNS 304
SL+C P A Y W +NG ++ + LF+ +T +G Y C N
Sbjct: 164 AVSLTC-DPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNP 222
Query: 305 VTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQ 364
V+ +R+ T+ L P + KP I + +KD +N TC + W+ Q
Sbjct: 223 VSA-SRSDPFTL---NLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQ 278
Query: 365 SLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY 416
SLP S R+K N L + V R + G Y CE+ + +S P+ LNV Y
Sbjct: 279 SLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLY 330
Score = 83.6 bits (205), Expect = 4e-16
Identities = 52/141 (36%), Positives = 70/141 (49%), Gaps = 14/141 (9%)
Query: 280 STQELFIPNITVNNSGSYTCHA------NNSVTGCNRTTVKTIIVTELSPVVAKPQIKAS 333
S L I N+T ++GSYT H N VTG T L KP I +S
Sbjct: 103 SNASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGHFTFT--------LYLETPKPSISSS 154
Query: 334 KTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGT 393
K ++V+LTC S W+ QSLP S R++LS+ N TL + V + AG
Sbjct: 155 KLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGP 214
Query: 394 YWCEVFNPISKNQSDPIMLNV 414
Y CE+ NP+S ++SDP LN+
Sbjct: 215 YECEIRNPVSASRSDPFTLNL 235
>gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a
[Homo sapiens]
Length = 426
Score = 298 bits (762), Expect = 1e-80
Identities = 184/426 (43%), Positives = 237/426 (55%), Gaps = 32/426 (7%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP R+ W+GLLLTASLL FWNPPTTAQ+T E+ P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGLLSAPPCTQRITWKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ D I Y + Q GPA SGRETIY NASLLIQNVTQ D G Y
Sbjct: 61 NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSY 120
Query: 121 TLQVIKSDLVNEEATGQ--FHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +I N TG F +Y E PKPSISS+ NP E +AV+ TC+PET D +YLW
Sbjct: 121 TLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLP+S RLQLS NRTL LL VT+ GPYECEI+NPVSA+RSDP TLN+
Sbjct: 181 WMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLP 240
Query: 239 TPTISPSDTYYRPGAN-LSLSCYAASNPPAQYSWLINGTFQQ---------STQELFIPN 288
P I+ ++ R + L+ +C S Y W +NG + L +P+
Sbjct: 241 KPYITINNLKPRENKDVLNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPS 299
Query: 289 ITVNNSGSYTCHANNSVTGCNR--TTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNL 346
+T N +G Y C + G T+ + +L P+I S T + + L
Sbjct: 300 VTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDL------PRIYPSFTYYRSG-EVLYL 352
Query: 347 TCST-NDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKN 405
+CS ++ W + S +++ + Q + + +G Y C V N +
Sbjct: 353 SCSADSNPPAQYSWTINGKFQLSGQKLFIPQ---------ITTKHSGLYACSVRNSATGK 403
Query: 406 QSDPIM 411
+S M
Sbjct: 404 ESSKSM 409
Score = 218 bits (556), Expect = 8e-57
Identities = 110/216 (50%), Positives = 139/216 (64%)
Query: 104 NASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAV 163
N +L + VT+ G Y ++ + ++ P+LPKP I+ NN P E+KD +
Sbjct: 199 NRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVL 258
Query: 164 AFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSA 223
FTCEP++++ TY+WW+N QSLPVSPR++ NR L L SVTRN+TGPY+CEI++
Sbjct: 259 NFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGG 318
Query: 224 NRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQE 283
RS PVTLNV YGPD P I PS TYYR G L LSC A SNPPAQYSW ING FQ S Q+
Sbjct: 319 IRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQK 378
Query: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVT 319
LFIP IT +SG Y C NS TG + T+ V+
Sbjct: 379 LFIPQITTKHSGLYACSVRNSATGKESSKSMTVKVS 414
Score = 87.4 bits (215), Expect = 3e-17
Identities = 67/232 (28%), Positives = 99/232 (42%), Gaps = 17/232 (7%)
Query: 197 NRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANL- 255
N +L + +VT+ D G Y I NR T +TP S S + P +
Sbjct: 104 NASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAME 163
Query: 256 --SLSCYAASNPPAQYSWLINGT---------FQQSTQELFIPNITVNNSGSYTCHANNS 304
SL+C P A Y W +NG ++ + LF+ +T +G Y C N
Sbjct: 164 AVSLTC-DPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNP 222
Query: 305 VTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQ 364
V+ +R+ T+ L P + KP I + +KD +N TC + W+ Q
Sbjct: 223 VSA-SRSDPFTL---NLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQ 278
Query: 365 SLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY 416
SLP S R+K N L + V R + G Y CE+ + +S P+ LNV Y
Sbjct: 279 SLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLY 330
Score = 83.6 bits (205), Expect = 4e-16
Identities = 52/141 (36%), Positives = 70/141 (49%), Gaps = 14/141 (9%)
Query: 280 STQELFIPNITVNNSGSYTCHA------NNSVTGCNRTTVKTIIVTELSPVVAKPQIKAS 333
S L I N+T ++GSYT H N VTG T L KP I +S
Sbjct: 103 SNASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGHFTFT--------LYLETPKPSISSS 154
Query: 334 KTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGT 393
K ++V+LTC S W+ QSLP S R++LS+ N TL + V + AG
Sbjct: 155 KLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGP 214
Query: 394 YWCEVFNPISKNQSDPIMLNV 414
Y CE+ NP+S ++SDP LN+
Sbjct: 215 YECEIRNPVSASRSDPFTLNL 235
>gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor
[Homo sapiens]
Length = 419
Score = 296 bits (757), Expect = 4e-80
Identities = 181/434 (41%), Positives = 238/434 (54%), Gaps = 29/434 (6%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP + W+GLLLTASLL FWNPPTTAQ+T E+ P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGPLSAPPCTQHITWKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ D + Y + Q GPA SGRET+Y NASLLIQNVTQ DTG Y
Sbjct: 61 NLTGYIWYKGQIRDLYHYVTSYIVDGQIIKYGPAYSGRETVYSNASLLIQNVTQEDTGSY 120
Query: 121 TLQVIKSDLVNEEATGQ--FHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +IK TG+ F +Y E PKPSISS+N NP E +AV TC+PET D +YLW
Sbjct: 121 TLHIIKRGDGTGGVTGRFTFTLYLETPKPSISSSNFNPREATEAVILTCDPETPDASYLW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLP++ LQLS NRTL L VT GPYECEI+NPVSA+RSDPVTLN+
Sbjct: 181 WMNGQSLPMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 240
Query: 239 TPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTF---------QQSTQELFIPNI 289
P I+ ++ R ++S + Y W +NG + + L +P++
Sbjct: 241 KPYITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPSV 300
Query: 290 TVNNSGSYTCHANNSVTG--CNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLT 347
T N +G Y C + G + T+ + +L P+I S T ++
Sbjct: 301 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDL------PRIYPSFTYYHSGQNLYLSC 354
Query: 348 CSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPIS-KNQ 406
+ ++ W + S ++ LSI + + +G Y C V N + K
Sbjct: 355 FADSNPPAQYSWTINGKFQLSGQK---------LSIPQITTKHSGLYACSVRNSATGKES 405
Query: 407 SDPIMLNVNYNALP 420
S + + V+ LP
Sbjct: 406 SKSVTVRVSDWTLP 419
>gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo
sapiens]
Length = 426
Score = 293 bits (750), Expect = 3e-79
Identities = 179/411 (43%), Positives = 229/411 (55%), Gaps = 24/411 (5%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG L AP R+ W+GLLLTASLL FWNPPTTA++T E+ P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGPLPAPSCTQRITWKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKGE D I+ Y + + GPA SGRET+Y NASLLIQNVT+ D G Y
Sbjct: 61 NLPGYFWYKGEMTDLYHYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQNVTRKDAGTY 120
Query: 121 TLQVIK-SDLVNEEATG-QFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +IK D EE F +Y E PKP ISS+N NP E +AV C+PET D +YLW
Sbjct: 121 TLHIIKRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAMEAVRLICDPETLDASYLW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLPV+ RLQLS NRTL L VT+ GPYECEI+NPVSA+RSDPVTLN+
Sbjct: 181 WMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 240
Query: 239 TPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQ---------STQELFIPNI 289
P I+ ++ R ++ + Y W +NG + L +P++
Sbjct: 241 IPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPGVKRPIENRILILPSV 300
Query: 290 TVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCS 349
T N +G Y C + G V I+ P + P+I S T ++++L+C
Sbjct: 301 TRNETGPYQCEIRDRYGGLRSNPV--ILNVLYGPDL--PRIYPSFTYYRSG-ENLDLSCF 355
Query: 350 TNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFN 400
T + ++ N K Q L I + R +G Y C V N
Sbjct: 356 TESNPPAEYFWTING--------KFQQSGQKLFIPQITRNHSGLYACSVHN 398
Score = 219 bits (559), Expect = 4e-57
Identities = 109/216 (50%), Positives = 142/216 (65%)
Query: 104 NASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAV 163
N +L + VT+ G Y ++ + ++ P+LP P I+ NN NP E+KD +
Sbjct: 199 NRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPIPYITINNLNPRENKDVL 258
Query: 164 AFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSA 223
AFTCEP++++ TY+WW+N QSLPVSP ++ NR L L SVTRN+TGPY+CEI++
Sbjct: 259 AFTCEPKSENYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYGG 318
Query: 224 NRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQE 283
RS+PV LNV YGPD P I PS TYYR G NL LSC+ SNPPA+Y W ING FQQS Q+
Sbjct: 319 LRSNPVILNVLYGPDLPRIYPSFTYYRSGENLDLSCFTESNPPAEYFWTINGKFQQSGQK 378
Query: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVT 319
LFIP IT N+SG Y C +NS TG + T+ V+
Sbjct: 379 LFIPQITRNHSGLYACSVHNSATGKEISKSMTVKVS 414
Score = 73.2 bits (178), Expect = 6e-13
Identities = 45/135 (33%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Query: 280 STQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTG 339
S L I N+T ++G+YT H R ++ T L KP I +S
Sbjct: 103 SNASLLIQNVTRKDAGTYTLHIIKRGDE-TREEIRHFTFT-LYLETPKPYISSSNLNPRE 160
Query: 340 DKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVF 399
++V L C S W+ QSLP + R++LS+ N TL + V + AG Y CE+
Sbjct: 161 AMEAVRLICDPETLDASYLWWMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIR 220
Query: 400 NPISKNQSDPIMLNV 414
NP+S ++SDP+ LN+
Sbjct: 221 NPVSASRSDPVTLNL 235
Score = 72.0 bits (175), Expect = 1e-12
Identities = 59/231 (25%), Positives = 89/231 (38%), Gaps = 15/231 (6%)
Query: 197 NRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPT--ISPSDTYYRPGAN 254
N +L + +VTR D G Y I R + T +TP IS S+ R
Sbjct: 104 NASLLIQNVTRKDAGTYTLHIIKRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAME 163
Query: 255 LSLSCYAASNPPAQYSWLINGT---------FQQSTQELFIPNITVNNSGSYTCHANNSV 305
A Y W +NG ++ + L++ +T +G Y C N V
Sbjct: 164 AVRLICDPETLDASYLWWMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPV 223
Query: 306 TGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQS 365
+ V L P + P I + +KD + TC + W+ QS
Sbjct: 224 SASRSDPV----TLNLLPKLPIPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQS 279
Query: 366 LPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY 416
LP S +K N L + V R + G Y CE+ + +S+P++LNV Y
Sbjct: 280 LPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNVLY 330
>gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]
Length = 426
Score = 289 bits (740), Expect = 4e-78
Identities = 181/425 (42%), Positives = 239/425 (56%), Gaps = 30/425 (7%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP R+ W+GLLLTASLL FWN PTTAQ+T E+ P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ D I Y + + GPA SGRET Y NASLLIQNVT+ D G Y
Sbjct: 61 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 120
Query: 121 TLQVIKSDLVNEEATGQ--FHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +IK D TG+ F ++ E PKPSISS+N NP E +AV+ TC+PET D +YLW
Sbjct: 121 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLP++ L+LS NRTL LL VT+ GPYECEI+NPVSA+RSDPVTLN+
Sbjct: 181 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 240
Query: 239 TPTISPSDTYYRPGAN-LSLSCYAASNPPAQYSWLINGTFQQ---------STQELFIPN 288
P I+ ++ R + L+ +C S Y W +NG + L +P+
Sbjct: 241 KPYITINNLNPRENKDVLNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPS 299
Query: 289 ITVNNSGSYTCHANNSVTG--CNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNL 346
+T N +G Y C + G + T+ + +L P+I S T + + L
Sbjct: 300 VTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDL------PRIYPSFTYYRSG-EVLYL 352
Query: 347 TCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQ 406
+CS + + S +E+ +L L I + + +G Y C V N + +
Sbjct: 353 SCSADSNPPA------QYSWTINEKFQLP--GQKLFIRHITTKHSGLYVCSVRNSATGKE 404
Query: 407 SDPIM 411
S M
Sbjct: 405 SSKSM 409
Score = 216 bits (549), Expect = 5e-56
Identities = 109/216 (50%), Positives = 139/216 (64%)
Query: 104 NASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAV 163
N +L + VT+ G Y ++ + ++ P+LPKP I+ NN NP E+KD +
Sbjct: 199 NRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVL 258
Query: 164 AFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSA 223
FTCEP++++ TY+WW+N QSLPVSPR++ NR L L SVTRN+TGPY+CEI++
Sbjct: 259 NFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGG 318
Query: 224 NRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQE 283
RSDPVTLNV YGPD P I PS TYYR G L LSC A SNPPAQYSW IN FQ Q+
Sbjct: 319 IRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLPGQK 378
Query: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVT 319
LFI +IT +SG Y C NS TG + T+ V+
Sbjct: 379 LFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVS 414
Score = 84.3 bits (207), Expect = 2e-16
Identities = 47/135 (34%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Query: 280 STQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTG 339
S L I N+T ++GSYT H G T + L KP I +S
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLE--TPKPSISSSNLNPRE 160
Query: 340 DKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVF 399
++V+LTC S W+ QSLP + +KLS+ N TL + V + AG Y CE+
Sbjct: 161 TMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIR 220
Query: 400 NPISKNQSDPIMLNV 414
NP+S ++SDP+ LN+
Sbjct: 221 NPVSASRSDPVTLNL 235
>gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1
[Homo sapiens]
Length = 419
Score = 284 bits (727), Expect = 1e-76
Identities = 178/435 (40%), Positives = 236/435 (54%), Gaps = 31/435 (7%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP R+ W+G+LLTASLL FWNPPTTAQ+T E+ P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ I Y + Q+ GPA SGRE +Y NASLLIQNVTQ D G Y
Sbjct: 61 NLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSY 120
Query: 121 TLQVIKSDLVNEEATGQ--FHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +IK TG F ++ E PKPSISS+N NP E +AV TC+P T +Y W
Sbjct: 121 TLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLP++ RLQLS NRTL + VT+ GPYECEI+NPVSA+RSDPVTLN+
Sbjct: 181 WMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLS 240
Query: 239 TPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQ---------STQELFIPNI 289
P I+ ++ R ++ + Y W +NG + L +PN+
Sbjct: 241 KPYITINNLNPRENKDVLTFTCEPKSKNYTYIWWLNGQSLPVSPRVKRPIENRILILPNV 300
Query: 290 TVNNSGSYTCHANNSVTG--CNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLT 347
T N +G Y C + G + T+ + +L P I S T +++ L+
Sbjct: 301 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDL------PSIYPSFTYYRSG-ENLYLS 353
Query: 348 C-STNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPIS-KN 405
C + ++ W + S ++ LSI + + +G Y C V N + K
Sbjct: 354 CFAESNPRAQYSWTINGKFQLSGQK---------LSIPQITTKHSGLYACSVRNSATGKE 404
Query: 406 QSDPIMLNVNYNALP 420
S I + V+ LP
Sbjct: 405 SSKSITVKVSDWILP 419
>gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo
sapiens]
Length = 428
Score = 284 bits (727), Expect = 1e-76
Identities = 178/442 (40%), Positives = 239/442 (54%), Gaps = 32/442 (7%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP R+ W+GLLLTA LL FWN PTTAQ+T E+ P V++GK+VLLLVHNLPQ
Sbjct: 1 MGPLSAPPCTQRITWKGLLLTALLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ D I Y + Q GPA SGRET+Y NASLLIQNVT+ D G Y
Sbjct: 61 NLAGYIWYKGQMKDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSY 120
Query: 121 TLQVIKSDLVNEEATGQ--FHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL ++K TG F +Y E PKPSISS+N P ED +AV+ TC+PET D +YLW
Sbjct: 121 TLHIVKRGDGTRGETGHFTFTLYLETPKPSISSSNLYPREDMEAVSLTCDPETPDASYLW 180
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
W+N QSLP++ LQLS RTL L VT+ GPYECEI+NPVSA+RSDPVTLN+
Sbjct: 181 WMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 240
Query: 239 TPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQ---------STQELFIPNI 289
P I+ ++ R ++ + Y W +NG + L +P++
Sbjct: 241 KPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 300
Query: 290 TVNNSGSYTCHANNSVTGCNR--TTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLT 347
T N +G Y C + G T+ + +L P+I S T +++ L+
Sbjct: 301 TRNETGPYQCEIQDRYGGIRSYPVTLNVLYGPDL------PRIYPS-FTYYHSGENLYLS 353
Query: 348 C-STNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQ 406
C + ++ W + S +++ + Q + + +G Y C V N + +
Sbjct: 354 CFADSNPPAEYSWTINGKFQLSGQKLFIPQ---------ITTKHSGLYACSVRNSATGME 404
Query: 407 SDPIMLNVNYNALPQENGLSPG 428
S M V +A P G PG
Sbjct: 405 SSKSM-TVKVSA-PSGTGHLPG 424
>gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [Homo
sapiens]
Length = 435
Score = 282 bits (722), Expect = 5e-76
Identities = 185/443 (41%), Positives = 242/443 (54%), Gaps = 34/443 (7%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP + W+GLLLTASLL FWN PTTAQ+ E+ P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ D I Y + Q GPA SGRET+Y NASLLIQNVTQ D G Y
Sbjct: 61 NLTGYIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
Query: 121 TLQVIKSDLVNEEATGQFHV--YPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +IK TG F V Y E PKPSISS+N NP E +AV C+PET D +YLW
Sbjct: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
+N Q+LP++ RLQLS NRTL L VT+ GPYECEI+NPVSA+RSDPVTLN+
Sbjct: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
Query: 239 TPTISPSDTYYRPGAN-LSLSCYAASNPPAQYSWLINGTFQQ---------STQELFIPN 288
P I+ ++ R + L+ +C S Y W +NG + L +P+
Sbjct: 240 MPYITINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPS 298
Query: 289 ITVNNSGSYTCHANNSVTG--CNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNL 346
+T N +G Y C + G N T+ + +L P+I S T ++++L
Sbjct: 299 VTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDL------PRIYPSFTYYRSG-ENLDL 351
Query: 347 TC-STNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPIS-K 404
+C + ++ W + S +++ + Q T S G Y C V N + K
Sbjct: 352 SCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTNHS---------GLYACSVRNSATGK 402
Query: 405 NQSDPIMLNVNYNALPQENGLSP 427
S +++ V+ A PQ P
Sbjct: 403 EISKSMIVKVSETASPQVTYAGP 425
>gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b
[Homo sapiens]
Length = 424
Score = 278 bits (711), Expect = 9e-75
Identities = 179/427 (41%), Positives = 234/427 (54%), Gaps = 33/427 (7%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP + W+GLLLTASLL FWN PTTAQ+ E+ P V+EGK+VLLLVHNLPQ
Sbjct: 1 MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L GY WYKG+ D I Y + Q GPA SGRET+Y NASLLIQNVTQ D G Y
Sbjct: 61 NLTGYIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
Query: 121 TLQVIKSDLVNEEATGQFHV--YPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178
TL +IK TG F V Y E PKPSISS+N NP E +AV C+PET D +YLW
Sbjct: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
Query: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238
+N Q+LP++ RLQLS NRTL L VT+ GPYECEI+NPVSA+RSDPVTLN+
Sbjct: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
Query: 239 TPTISPSDTYYRPGAN-LSLSCYAASNPPAQYSWLINGTFQQ---------STQELFIPN 288
P I+ ++ R + L+ +C S Y W +NG + L +P+
Sbjct: 240 MPYITINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPS 298
Query: 289 ITVNNSGSYTCHANNSVTG--CNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNL 346
+T N +G Y C + G N T+ + +L P+I S T ++++L
Sbjct: 299 VTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDL------PRIYPSFTYYRSG-ENLDL 351
Query: 347 TC-STNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKN 405
+C + ++ W + S +++ + Q T S G Y C V N +
Sbjct: 352 SCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTNHS---------GLYACSVRNSATGK 402
Query: 406 QSDPIML 412
+ M+
Sbjct: 403 EISKSMI 409
Score = 79.0 bits (193), Expect = 1e-14
Identities = 62/232 (26%), Positives = 91/232 (39%), Gaps = 17/232 (7%)
Query: 197 NRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLS 256
N +L + +VT+ D G Y I VT +TP S S + P +
Sbjct: 103 NASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVME 162
Query: 257 ---LSCYAASNPPAQYSWLINGT---------FQQSTQELFIPNITVNNSGSYTCHANNS 304
L C P A Y WL+NG ++ + L++ +T +G Y C N
Sbjct: 163 AVRLIC-DPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNP 221
Query: 305 VTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQ 364
V+ V L P + P I + KD + TC + W+ Q
Sbjct: 222 VSASRSDPV----TLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQ 277
Query: 365 SLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY 416
SLP S R+K N L + V R + G Y CE+ + +S+P+ LNV Y
Sbjct: 278 SLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLY 329
Score = 77.4 bits (189), Expect = 3e-14
Identities = 45/135 (33%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Query: 280 STQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTG 339
S L I N+T ++GSYT H G T L KP I +S
Sbjct: 102 SNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVT--GYFTVTLYSETPKPSISSSNLNPRE 159
Query: 340 DKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVF 399
++V L C S W Q+LP + R++LS+ N TL + V + AG Y CE+
Sbjct: 160 VMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIR 219
Query: 400 NPISKNQSDPIMLNV 414
NP+S ++SDP+ LN+
Sbjct: 220 NPVSASRSDPVTLNL 234
>gi|121114300 carcinoembryonic antigen-related cell adhesion
molecule 3 precursor [Homo sapiens]
Length = 252
Score = 244 bits (624), Expect = 1e-64
Identities = 122/143 (85%), Positives = 125/143 (87%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG SA HR +PWQGLLLTASLL FWNPPTTA+LT ESMP +VAEGKEVLLLVHNLPQ
Sbjct: 1 MGPPSASPHRECIPWQGLLLTASLLNFWNPPTTAKLTIESMPLSVAEGKEVLLLVHNLPQ 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
LFGYSWYKGERVDGN IVGY IGTQQATPG A SGRETIY NASLLIQNVTQND GFY
Sbjct: 61 HLFGYSWYKGERVDGNSLIVGYVIGTQQATPGAAYSGRETIYTNASLLIQNVTQNDIGFY 120
Query: 121 TLQVIKSDLVNEEATGQFHVYPE 143
TLQVIKSDLVNEEATGQFHVY E
Sbjct: 121 TLQVIKSDLVNEEATGQFHVYQE 143
Score = 62.8 bits (151), Expect = 8e-10
Identities = 52/148 (35%), Positives = 70/148 (47%), Gaps = 16/148 (10%)
Query: 378 NTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGV 437
N +L I V + D G Y +V N+ +V P GL GA+AGIV GV
Sbjct: 104 NASLLIQNVTQNDIGFYTLQVIKSDLVNEEATGQFHVYQENAP---GLPVGAVAGIVTGV 160
Query: 438 VALVALIAVALACFLHFGKTGRASDQRDLTEHKPSVSNHTQDHSNDPPNKMNEVTYSTLN 497
+ VAL+A AL CFL KTGR S QRDL E +P + S+ M+ ++ +
Sbjct: 161 LVGVALVA-ALVCFLLLAKTGRTSIQRDLKEQQPQALAPGRGPSHSSAFSMSPLSTA--- 216
Query: 498 FEAQQPTQPTSASPSLTATEIIYSEVKK 525
+A P T+AS IY E+ K
Sbjct: 217 -QAPLPNPRTAAS--------IYEELLK 235
>gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c
[Homo sapiens]
Length = 297
Score = 230 bits (586), Expect = 3e-60
Identities = 133/320 (41%), Positives = 174/320 (54%), Gaps = 27/320 (8%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP R+ W+GLLLT T + + S N E E + L +
Sbjct: 1 MGLLSAPPCTQRITWKGLLLTVE---------TPKPSISSSKLNPREAMEAVSLTCDPET 51
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
Y W+ G ++ P + + N +L + VT+ G Y
Sbjct: 52 PDASYLWWMN----------GQSL--------PMSHRLQLSETNRTLFLLGVTKYTAGPY 93
Query: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 180
++ + ++ P+LPKP I+ NN P E+KD + FTCEP++++ TY+WW+
Sbjct: 94 ECEIRNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWL 153
Query: 181 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 240
N QSLPVSPR++ NR L L SVTRN+TGPY+CEI++ RS PVTLNV YGPD P
Sbjct: 154 NGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLP 213
Query: 241 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 300
I PS TYYR G L LSC A SNPPAQYSW ING FQ S Q+LFIP IT +SG Y C
Sbjct: 214 RIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQKLFIPQITTKHSGLYACS 273
Query: 301 ANNSVTGCNRTTVKTIIVTE 320
NS TG + T+ V++
Sbjct: 274 VRNSATGKESSKSMTVKVSD 293
Score = 77.4 bits (189), Expect = 3e-14
Identities = 58/196 (29%), Positives = 86/196 (43%), Gaps = 15/196 (7%)
Query: 231 LNVTYGPDTPTISPSDTYYRPGAN-LSLSCYAASNPPAQYSWLINGT---------FQQS 280
L +T P+IS S R +SL+C P A Y W +NG ++
Sbjct: 18 LLLTVETPKPSISSSKLNPREAMEAVSLTC-DPETPDASYLWWMNGQSLPMSHRLQLSET 76
Query: 281 TQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGD 340
+ LF+ +T +G Y C N V+ +R+ T+ L P + KP I + +
Sbjct: 77 NRTLFLLGVTKYTAGPYECEIRNPVSA-SRSDPFTL---NLLPKLPKPYITINNLKPREN 132
Query: 341 KDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFN 400
KD +N TC + W+ QSLP S R+K N L + V R + G Y CE+ +
Sbjct: 133 KDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRD 192
Query: 401 PISKNQSDPIMLNVNY 416
+S P+ LNV Y
Sbjct: 193 QYGGIRSYPVTLNVLY 208
Score = 75.5 bits (184), Expect = 1e-13
Identities = 41/105 (39%), Positives = 60/105 (57%), Gaps = 3/105 (2%)
Query: 310 RTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSS 369
R T K +++T +P KP I +SK ++V+LTC S W+ QSLP S
Sbjct: 12 RITWKGLLLTVETP---KPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMS 68
Query: 370 ERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNV 414
R++LS+ N TL + V + AG Y CE+ NP+S ++SDP LN+
Sbjct: 69 HRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNL 113
>gi|52317156 carcinoembryonic antigen-related cell adhesion molecule
isoform 2 [Homo sapiens]
Length = 292
Score = 225 bits (574), Expect = 7e-59
Identities = 118/235 (50%), Positives = 148/235 (62%), Gaps = 1/235 (0%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG SA HR +PWQGLLLTASLLTFWN PTTA L S PF VAEG+ V L V LP+
Sbjct: 1 MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L+ Y WYKG+ V+ N+ I Y I T TPGPA SGRETI P+ L QNVT DTG+Y
Sbjct: 61 NLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYY 120
Query: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 180
LQV + E+A+ VY + +PSI + +S V +K +V TC T++ W
Sbjct: 121 NLQVTYRNSQIEQASHHLRVYESVAQPSIQA-SSTTVTEKGSVVLTCHTNNTGTSFQWIF 179
Query: 181 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTY 235
NNQ L V+ R++LS N LT+ + + D G Y+CE+ NPVS+NRSDP+ L V Y
Sbjct: 180 NNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKY 234
Score = 142 bits (358), Expect = 7e-34
Identities = 85/192 (44%), Positives = 115/192 (59%), Gaps = 17/192 (8%)
Query: 283 ELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKD 342
+L N+T+ ++G Y N VT N + + VA+P I+AS TTVT +K
Sbjct: 106 DLHFQNVTLEDTGYY----NLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVT-EKG 160
Query: 343 SVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPI 402
SV LTC TN+TG S +W F NQ L ++RMKLS N L+I+P+++EDAG Y CEV NP+
Sbjct: 161 SVVLTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPV 220
Query: 403 SKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRASD 462
S N+SDP+ L V Y +N L G + G+++G +L+ AL CFL KTGRASD
Sbjct: 221 SSNRSDPLKLTVKY-----DNTL--GILIGVLVG-----SLLVAALVCFLLLRKTGRASD 268
Query: 463 QRDLTEHKPSVS 474
Q D E +P S
Sbjct: 269 QSDFREQQPPAS 280
>gi|148612793 carcinoembryonic antigen-related cell adhesion
molecule isoform 1 [Homo sapiens]
Length = 293
Score = 223 bits (569), Expect = 3e-58
Identities = 118/239 (49%), Positives = 149/239 (62%), Gaps = 1/239 (0%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG SA HR +PWQGLLLTASLLTFWN PTTA L S PF VAEG+ V L V LP+
Sbjct: 1 MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
L+ Y WYKG+ V+ N+ I Y I T TPGPA SGRETI P+ L QNVT DTG+Y
Sbjct: 61 NLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYY 120
Query: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 180
LQV + E+A+ VY + +PSI + +S V +K +V TC T++ W
Sbjct: 121 NLQVTYRNSQIEQASHHLRVYESVAQPSIQA-SSTTVTEKGSVVLTCHTNNTGTSFQWIF 179
Query: 181 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDT 239
NNQ L V+ R++LS N LT+ + + D G Y+CE+ NPVS+NRSDP+ L V +T
Sbjct: 180 NNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKSDDNT 238
Score = 139 bits (351), Expect = 5e-33
Identities = 84/192 (43%), Positives = 114/192 (59%), Gaps = 16/192 (8%)
Query: 283 ELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKD 342
+L N+T+ ++G Y N VT N + + VA+P I+AS TTVT +K
Sbjct: 106 DLHFQNVTLEDTGYY----NLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVT-EKG 160
Query: 343 SVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPI 402
SV LTC TN+TG S +W F NQ L ++RMKLS N L+I+P+++EDAG Y CEV NP+
Sbjct: 161 SVVLTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPV 220
Query: 403 SKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRASD 462
S N+SDP+ L V +N L G + G+++G +L+ AL CFL KTGRASD
Sbjct: 221 SSNRSDPLKLTVK----SDDNTL--GILIGVLVG-----SLLVAALVCFLLLRKTGRASD 269
Query: 463 QRDLTEHKPSVS 474
Q D E +P S
Sbjct: 270 QSDFREQQPPAS 281
>gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2
[Homo sapiens]
Length = 213
Score = 214 bits (546), Expect = 1e-55
Identities = 107/176 (60%), Positives = 123/176 (69%)
Query: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTL 202
E PKPSISS+N NP E + V TC PET D +YLWW+N QSLP++ R+QLS NRTL L
Sbjct: 23 ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82
Query: 203 LSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAA 262
VT+ GPYECEI N SA+RSDPVTLN+ +GPD P I PS T Y G NL LSC+A
Sbjct: 83 FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFAN 142
Query: 263 SNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIV 318
SNPPAQYSW ING FQ S Q+LFIP IT ++G Y C A NS TG +T TI V
Sbjct: 143 SNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRV 198
Score = 67.0 bits (162), Expect = 4e-11
Identities = 37/101 (36%), Positives = 57/101 (56%), Gaps = 3/101 (2%)
Query: 314 KTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMK 373
K +++T +P KP I +S ++V LTC+ S W+ QSLP + RM+
Sbjct: 16 KGLLLTVETP---KPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQ 72
Query: 374 LSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNV 414
LS+ N TL + V + AG Y CE++N S ++SDP+ LN+
Sbjct: 73 LSETNRTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNL 113
Score = 42.4 bits (98), Expect = 0.001
Identities = 59/248 (23%), Positives = 90/248 (36%), Gaps = 45/248 (18%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP + W+GLLLT T + + S N E E ++L N
Sbjct: 1 MGPLSAPPCTEHIKWKGLLLTVE---------TPKPSISSSNLNPREAMETVILTCNPET 51
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
Y W+ N Q + P + N +L + VT+ G Y
Sbjct: 52 PDASYLWWM------NGQSL------------PMTHRMQLSETNRTLFLFGVTKYTAGPY 93
Query: 121 TLQVIKSDLVNEEATGQFHVY--PELPK--PSISSNNSNPVEDKDAVAFTCEPETQDTTY 176
++ S + ++ P+LP+ PS++S S D A + P Y
Sbjct: 94 ECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFANSNPP----AQY 149
Query: 177 LWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSD-PVTLNVTY 235
W IN + QLS + L + +T G Y C +N + S +T+ V
Sbjct: 150 SWTING-------KFQLS--GQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIA 200
Query: 236 GPDTPTIS 243
P T +
Sbjct: 201 PPGLGTFA 208
Score = 30.0 bits (66), Expect = 5.4
Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 9/83 (10%)
Query: 231 LNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLING---------TFQQST 281
L +T P+IS S+ R + P A Y W +NG ++
Sbjct: 18 LLLTVETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETN 77
Query: 282 QELFIPNITVNNSGSYTCHANNS 304
+ LF+ +T +G Y C NS
Sbjct: 78 RTLFLFGVTKYTAGPYECEIWNS 100
>gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2
[Homo sapiens]
Length = 213
Score = 214 bits (546), Expect = 1e-55
Identities = 107/176 (60%), Positives = 123/176 (69%)
Query: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTL 202
E PKPSISS+N NP E + V TC PET D +YLWW+N QSLP++ R+QLS NRTL L
Sbjct: 23 ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82
Query: 203 LSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAA 262
VT+ GPYECEI N SA+RSDPVTLN+ +GPD P I PS T Y G NL LSC+A
Sbjct: 83 FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFAN 142
Query: 263 SNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIV 318
SNPPAQYSW ING FQ S Q+LFIP IT ++G Y C A NS TG +T TI V
Sbjct: 143 SNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRV 198
Score = 67.0 bits (162), Expect = 4e-11
Identities = 37/101 (36%), Positives = 57/101 (56%), Gaps = 3/101 (2%)
Query: 314 KTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMK 373
K +++T +P KP I +S ++V LTC+ S W+ QSLP + RM+
Sbjct: 16 KGLLLTVETP---KPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQ 72
Query: 374 LSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNV 414
LS+ N TL + V + AG Y CE++N S ++SDP+ LN+
Sbjct: 73 LSETNRTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNL 113
Score = 42.4 bits (98), Expect = 0.001
Identities = 59/248 (23%), Positives = 90/248 (36%), Gaps = 45/248 (18%)
Query: 1 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60
MG LSAP + W+GLLLT T + + S N E E ++L N
Sbjct: 1 MGPLSAPPCTEHIKWKGLLLTVE---------TPKPSISSSNLNPREAMETVILTCNPET 51
Query: 61 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120
Y W+ N Q + P + N +L + VT+ G Y
Sbjct: 52 PDASYLWWM------NGQSL------------PMTHRMQLSETNRTLFLFGVTKYTAGPY 93
Query: 121 TLQVIKSDLVNEEATGQFHVY--PELPK--PSISSNNSNPVEDKDAVAFTCEPETQDTTY 176
++ S + ++ P+LP+ PS++S S D A + P Y
Sbjct: 94 ECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFANSNPP----AQY 149
Query: 177 LWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSD-PVTLNVTY 235
W IN + QLS + L + +T G Y C +N + S +T+ V
Sbjct: 150 SWTING-------KFQLS--GQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIA 200
Query: 236 GPDTPTIS 243
P T +
Sbjct: 201 PPGLGTFA 208
Score = 30.0 bits (66), Expect = 5.4
Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 9/83 (10%)
Query: 231 LNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLING---------TFQQST 281
L +T P+IS S+ R + P A Y W +NG ++
Sbjct: 18 LLLTVETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETN 77
Query: 282 QELFIPNITVNNSGSYTCHANNS 304
+ LF+ +T +G Y C NS
Sbjct: 78 RTLFLFGVTKYTAGPYECEIWNS 100
>gi|156564390 carcinoembryonic antigen-related cell adhesion
molecule 20 4L [Homo sapiens]
Length = 503
Score = 197 bits (500), Expect = 3e-50
Identities = 123/366 (33%), Positives = 192/366 (52%), Gaps = 20/366 (5%)
Query: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTL 202
EL KPSI+ + +E KD V F C + + T W NN S+ R+QLS + LT+
Sbjct: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
Query: 203 LSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTI-------SPSDTYYRPGANL 255
L V R D+G Y+CE ++ + + RSDP+ L+V YGPD I S G+++
Sbjct: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
Query: 256 SLSCYAASNPPAQYSW-LINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVK 314
+ S+PP Y+W L++ +T+ I ++ + G Y C +NS T +
Sbjct: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
Query: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKL 374
+ V E + PQ+ S + + SV+LTC T + ++++WF Q L SE ++L
Sbjct: 246 KVRVLE---TLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQL 302
Query: 375 SQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIV 434
S N TL I+ ++R D G Y CEV+N S+ +S+P+ L +N PQ + LS GAIAGIV
Sbjct: 303 SADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN---CPQSSSLSSGAIAGIV 359
Query: 435 IGVVALVALIAVALACFLHFGKTGRASDQRDLTE---HKPSVSNHTQDHSNDPPNKMNEV 491
IG++A++A +A L FL+ R S R TE H+ S ++H +P ++
Sbjct: 360 IGILAVIA-VASELGYFLYIRNARRPS--RKTTEDPSHETSQPIPKEEHPTEPSSESLSP 416
Query: 492 TYSTLN 497
Y ++
Sbjct: 417 EYCNIS 422
Score = 86.3 bits (212), Expect = 6e-17
Identities = 50/127 (39%), Positives = 68/127 (53%)
Query: 312 TVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSER 371
T +T + S +AKP I S T KD V C+T D I+I W N S+ ER
Sbjct: 54 TPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHER 113
Query: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIA 431
M+LS+ L+I V+RED+GTY CE + + +SDPI L+V Y P E L G +
Sbjct: 114 MQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVAS 173
Query: 432 GIVIGVV 438
G V+ V+
Sbjct: 174 GEVVEVM 180
Score = 73.2 bits (178), Expect = 6e-13
Identities = 44/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 109 IQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTC 167
I V++ G Y V S ++ T + V L P + ++ N VE+ +V TC
Sbjct: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC 276
Query: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSD 227
+ Q W+++ Q L S LQLS NRTL + + RNDTGPY CE+ N S RS+
Sbjct: 277 QTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
Query: 228 PVTLNV 233
P+ L +
Sbjct: 337 PLELTI 342
Score = 61.6 bits (148), Expect = 2e-09
Identities = 75/327 (22%), Positives = 123/327 (37%), Gaps = 47/327 (14%)
Query: 15 WQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ--QLFGYSWYKGE- 71
W G+LL+ASL T W+PP AQLT + P + + ++V+L V P+ Q+ G S +
Sbjct: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
Query: 72 --RVDGNRQIVGYAIGTQQATPGPANSGRETIYPNAS---------------LLIQNVTQ 114
V I + T T N + N S L I V +
Sbjct: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
Query: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167
D+G Y + + L+++ + F P P ++S V + ++ F
Sbjct: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
Query: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRS- 226
E ++ W S+ LS+ RT T+ +V+R G Y C + N + S
Sbjct: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
Query: 227 DPVTLNVTYGPDTPTISPSDTYYRPGA-NLSLSCYAASNPPAQYSWLING---------T 276
+ + V P + PS A ++ L+C N W ++G
Sbjct: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
Query: 277 FQQSTQELFIPNITVNNSGSYTCHANN 303
+ L I + N++G Y C N
Sbjct: 302 LSADNRTLIIHGLQRNDTGPYACEVWN 328
Score = 30.4 bits (67), Expect = 4.2
Identities = 44/209 (21%), Positives = 78/209 (37%), Gaps = 38/209 (18%)
Query: 219 NPVSANRSDPVTLNVTYGPDTP--------------TISPSD--------TYYRPGANLS 256
NP+ A +S+ V L V P TP +SP T+Y +++
Sbjct: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
Query: 257 LSCYAASNPPAQYSWLINGTFQQSTQELFIPNITV--NNSGSYTCHANNSVTGCNRTTVK 314
++ + SN S + + Q S + + V +SG+Y C A +++ +
Sbjct: 97 ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
Query: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTC---STNDTGISIRWFFKNQSLPSSER 371
+ PV K + + V + ++T + + + WF + L + R
Sbjct: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTR 213
Query: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFN 400
T +I+ V RE G Y C V N
Sbjct: 214 --------TFTIHAVSREHEGLYRCLVSN 234
>gi|156564388 carcinoembryonic antigen-related cell adhesion
molecule 20 4S [Homo sapiens]
Length = 491
Score = 197 bits (500), Expect = 3e-50
Identities = 123/366 (33%), Positives = 192/366 (52%), Gaps = 20/366 (5%)
Query: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTL 202
EL KPSI+ + +E KD V F C + + T W NN S+ R+QLS + LT+
Sbjct: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
Query: 203 LSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTI-------SPSDTYYRPGANL 255
L V R D+G Y+CE ++ + + RSDP+ L+V YGPD I S G+++
Sbjct: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
Query: 256 SLSCYAASNPPAQYSW-LINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVK 314
+ S+PP Y+W L++ +T+ I ++ + G Y C +NS T +
Sbjct: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
Query: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKL 374
+ V E + PQ+ S + + SV+LTC T + ++++WF Q L SE ++L
Sbjct: 246 KVRVLE---TLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQL 302
Query: 375 SQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIV 434
S N TL I+ ++R D G Y CEV+N S+ +S+P+ L +N PQ + LS GAIAGIV
Sbjct: 303 SADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN---CPQSSSLSSGAIAGIV 359
Query: 435 IGVVALVALIAVALACFLHFGKTGRASDQRDLTE---HKPSVSNHTQDHSNDPPNKMNEV 491
IG++A++A +A L FL+ R S R TE H+ S ++H +P ++
Sbjct: 360 IGILAVIA-VASELGYFLYIRNARRPS--RKTTEDPSHETSQPIPKEEHPTEPSSESLSP 416
Query: 492 TYSTLN 497
Y ++
Sbjct: 417 EYCNIS 422
Score = 86.3 bits (212), Expect = 6e-17
Identities = 50/127 (39%), Positives = 68/127 (53%)
Query: 312 TVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSER 371
T +T + S +AKP I S T KD V C+T D I+I W N S+ ER
Sbjct: 54 TPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHER 113
Query: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIA 431
M+LS+ L+I V+RED+GTY CE + + +SDPI L+V Y P E L G +
Sbjct: 114 MQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVAS 173
Query: 432 GIVIGVV 438
G V+ V+
Sbjct: 174 GEVVEVM 180
Score = 73.2 bits (178), Expect = 6e-13
Identities = 44/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 109 IQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTC 167
I V++ G Y V S ++ T + V L P + ++ N VE+ +V TC
Sbjct: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC 276
Query: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSD 227
+ Q W+++ Q L S LQLS NRTL + + RNDTGPY CE+ N S RS+
Sbjct: 277 QTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
Query: 228 PVTLNV 233
P+ L +
Sbjct: 337 PLELTI 342
Score = 61.6 bits (148), Expect = 2e-09
Identities = 75/327 (22%), Positives = 123/327 (37%), Gaps = 47/327 (14%)
Query: 15 WQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ--QLFGYSWYKGE- 71
W G+LL+ASL T W+PP AQLT + P + + ++V+L V P+ Q+ G S +
Sbjct: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
Query: 72 --RVDGNRQIVGYAIGTQQATPGPANSGRETIYPNAS---------------LLIQNVTQ 114
V I + T T N + N S L I V +
Sbjct: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
Query: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167
D+G Y + + L+++ + F P P ++S V + ++ F
Sbjct: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
Query: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRS- 226
E ++ W S+ LS+ RT T+ +V+R G Y C + N + S
Sbjct: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
Query: 227 DPVTLNVTYGPDTPTISPSDTYYRPGA-NLSLSCYAASNPPAQYSWLING---------T 276
+ + V P + PS A ++ L+C N W ++G
Sbjct: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
Query: 277 FQQSTQELFIPNITVNNSGSYTCHANN 303
+ L I + N++G Y C N
Sbjct: 302 LSADNRTLIIHGLQRNDTGPYACEVWN 328
Score = 30.4 bits (67), Expect = 4.2
Identities = 44/209 (21%), Positives = 78/209 (37%), Gaps = 38/209 (18%)
Query: 219 NPVSANRSDPVTLNVTYGPDTP--------------TISPSD--------TYYRPGANLS 256
NP+ A +S+ V L V P TP +SP T+Y +++
Sbjct: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
Query: 257 LSCYAASNPPAQYSWLINGTFQQSTQELFIPNITV--NNSGSYTCHANNSVTGCNRTTVK 314
++ + SN S + + Q S + + V +SG+Y C A +++ +
Sbjct: 97 ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
Query: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTC---STNDTGISIRWFFKNQSLPSSER 371
+ PV K + + V + ++T + + + WF + L + R
Sbjct: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTR 213
Query: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFN 400
T +I+ V RE G Y C V N
Sbjct: 214 --------TFTIHAVSREHEGLYRCLVSN 234
>gi|85861202 carcinoembryonic antigen-related cell adhesion molecule
16 [Homo sapiens]
Length = 484
Score = 178 bits (452), Expect = 9e-45
Identities = 112/326 (34%), Positives = 163/326 (50%), Gaps = 21/326 (6%)
Query: 18 LLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNR 77
LLL+A TF N +T E P +EG V L+VH L +L YSWY G + +
Sbjct: 68 LLLSA---TFLNVGAEISITLE--PAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122
Query: 78 QIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQ 137
+ Y + T TPGPA++GRE + P+ SL IQ + +G Y LQ L E G
Sbjct: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182
Query: 138 FHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGN 197
V+ L +P++ +N++ VE +D + C + W+ N +LPV+ RL LS
Sbjct: 183 VQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDG 242
Query: 198 RTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPG----- 252
R L + R + G Y+CE+ NPVS +RS+P+ L V +GP+ I D+ R G
Sbjct: 243 RVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAIL-QDSTTRTGCTIKV 301
Query: 253 ---ANLSLSCYAASNPPAQYSWLINGTFQQSTQE-LFIPNITVNNSGSYTCHANNSVT-- 306
+L+L C + S P +Y W NG ++ Q+ L I ++T G+YTC A N+ T
Sbjct: 302 DFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLL 361
Query: 307 -GCNRTTVK---TIIVTELSPVVAKP 328
G VK + T + PV KP
Sbjct: 362 SGSASVVVKLSAAAVATMIVPVPTKP 387
Score = 77.0 bits (188), Expect = 4e-14
Identities = 34/97 (35%), Positives = 61/97 (62%)
Query: 320 ELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNT 379
++ ++A+P + A+ T + +D++ L CS+ +RWFF +LP + R+ LS
Sbjct: 184 QVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGR 243
Query: 380 TLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY 416
L+ + ++RE+AG Y CEV+NP+S ++S+PI L V +
Sbjct: 244 VLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYF 280
Score = 68.9 bits (167), Expect = 1e-11
Identities = 38/102 (37%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Query: 41 MPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRET 100
+P EG++V L V P+ L Y+WY+G + NR + GT A GPA++GRE
Sbjct: 383 VPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGTWIA--GPAHTGREV 440
Query: 101 IYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYP 142
+PN SLL+Q + DTG YTL+ + E + V P
Sbjct: 441 GFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAP 482
>gi|156564378 carcinoembryonic antigen-related cell adhesion
molecule 20 5L [Homo sapiens]
Length = 596
Score = 167 bits (422), Expect = 3e-41
Identities = 95/282 (33%), Positives = 149/282 (52%), Gaps = 11/282 (3%)
Query: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTL 202
EL KPSI+ + +E KD V F C + + T W NN S+ R+QLS + LT+
Sbjct: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
Query: 203 LSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTI-------SPSDTYYRPGANL 255
L V R D+G Y+CE ++ + + RSDP+ L+V YGPD I S G+++
Sbjct: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
Query: 256 SLSCYAASNPPAQYSW-LINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVK 314
+ S+PP Y+W L++ +T+ I ++ + G Y C +NS T +
Sbjct: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
Query: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKL 374
+ V E + PQ+ S + + SV+LTC T + ++++WF Q L SE ++L
Sbjct: 246 KVRVLE---TLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQL 302
Query: 375 SQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY 416
S N TL I+ ++R D G Y CEV+N S+ +S+P+ L +NY
Sbjct: 303 SADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINY 344
Score = 117 bits (294), Expect = 2e-26
Identities = 76/224 (33%), Positives = 115/224 (51%), Gaps = 11/224 (4%)
Query: 109 IQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTC 167
I V++ G Y V S ++ T + V L P + ++ N VE+ +V TC
Sbjct: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC 276
Query: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSD 227
+ Q W+++ Q L S LQLS NRTL + + RNDTGPY CE+ N S RS+
Sbjct: 277 QTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
Query: 228 PVTLNVTYGPDTPTISP-------SDTYYRPGANLSLSCYAASNPPAQYSW-LINGTFQQ 279
P+ L + YGPD I+ S ++L+L C+A S P A+Y W L + T +
Sbjct: 337 PLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEH 396
Query: 280 STQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSP 323
++L I +T + G Y C A+NS+TG R+T +++V + P
Sbjct: 397 LGEQLIIRALTWEHDGIYNCTASNSLTGLARST--SVLVKVVGP 438
Score = 90.9 bits (224), Expect = 3e-18
Identities = 121/528 (22%), Positives = 208/528 (39%), Gaps = 68/528 (12%)
Query: 15 WQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ--QLFGYSWYKGE- 71
W G+LL+ASL T W+PP AQLT + P + + ++V+L V P+ Q+ G S +
Sbjct: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
Query: 72 --RVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQN---------------VTQ 114
V I + T T N + N S++ V +
Sbjct: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
Query: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167
D+G Y + + L+++ + F P P ++S V + ++ F
Sbjct: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
Query: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRS- 226
E ++ W S+ LS+ RT T+ +V+R G Y C + N + S
Sbjct: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
Query: 227 DPVTLNVTYGPDTPTISPSDTYYRPGA-NLSLSCYAASNPPAQYSWLINGT--------- 276
+ + V P + PS A ++ L+C N W ++G
Sbjct: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
Query: 277 FQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPV-VAKPQIKASKT 335
+ L I + N++G Y C N + ++ I V + + +
Sbjct: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMIS 361
Query: 336 TVTGD-KDSVNLTC-STNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGT 393
T+ + S+ L C + + G RW ++ + E + L I + E G
Sbjct: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST---GEHL-----GEQLIIRALTWEHDGI 413
Query: 394 YWCEVFNPISK-NQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALIAVALACFL 452
Y C N ++ +S +++ V PQ + LS GAIAGIVIG++A++A +A L FL
Sbjct: 414 YNCTASNSLTGLARSTSVLVKV---VGPQSSSLSSGAIAGIVIGILAVIA-VASELGYFL 469
Query: 453 HFGKTGRASDQRDLTE---HKPSVSNHTQDHSNDPPNKMNEVTYSTLN 497
+ R S R TE H+ S ++H +P ++ Y ++
Sbjct: 470 YIRNARRPS--RKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNIS 515
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,739,675
Number of Sequences: 37866
Number of extensions: 1015233
Number of successful extensions: 5673
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 180
Number of HSP's successfully gapped in prelim test: 274
Number of HSP's that attempted gapping in prelim test: 2716
Number of HSP's gapped (non-prelim): 1838
length of query: 526
length of database: 18,247,518
effective HSP length: 107
effective length of query: 419
effective length of database: 14,195,856
effective search space: 5948063664
effective search space used: 5948063664
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.