Guide to the Human Genome
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Search of human proteins with 113205075

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|113205075 amyotrophic lateral sclerosis 2 (juvenile)
chromosome region, candidate 4 isoform a [Homo sapiens]
         (408 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|113205075 amyotrophic lateral sclerosis 2 (juvenile) chromoso...   795   0.0  
gi|113205077 amyotrophic lateral sclerosis 2 (juvenile) chromoso...   768   0.0  
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    42   0.001
gi|110349719 titin isoform N2-A [Homo sapiens]                         41   0.002
gi|224458301 family with sequence similarity 186, member A [Homo...    40   0.004
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   40   0.004
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    40   0.004
gi|116268091 PHD finger protein 23 [Homo sapiens]                      39   0.006
gi|91208420 bassoon protein [Homo sapiens]                             39   0.006
gi|58082089 hypothetical protein LOC161394 [Homo sapiens]              38   0.014
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]            38   0.019
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    37   0.032
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    37   0.032
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    37   0.032
gi|61097912 nucleolar protein with MIF4G domain 1 [Homo sapiens]       37   0.032
gi|89886237 cyclin I family, member 2 [Homo sapiens]                   37   0.032
gi|24497513 homeobox A3 isoform a [Homo sapiens]                       37   0.042
gi|13562112 homeobox A3 isoform a [Homo sapiens]                       37   0.042
gi|118498364 dapper 1 isoform 2 [Homo sapiens]                         37   0.042
gi|24158478 dapper 1 isoform 1 [Homo sapiens]                          37   0.042
gi|114842410 zinc finger CCCH-type containing 11A [Homo sapiens]       37   0.042
gi|169204941 PREDICTED: similar to Nucleolar protein 5A [Homo sa...    36   0.055
gi|169205573 PREDICTED: similar to Nucleolar protein 5A [Homo sa...    36   0.055
gi|169203848 PREDICTED: hypothetical protein [Homo sapiens]            36   0.055
gi|4505257 moesin [Homo sapiens]                                       36   0.055
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap...    36   0.055
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap...    36   0.055
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi...    36   0.055
gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]         36   0.072
gi|148839382 ring finger protein 169 [Homo sapiens]                    36   0.072

>gi|113205075 amyotrophic lateral sclerosis 2 (juvenile) chromosome
           region, candidate 4 isoform a [Homo sapiens]
          Length = 408

 Score =  795 bits (2053), Expect = 0.0
 Identities = 408/408 (100%), Positives = 408/408 (100%)

Query: 1   MRTDSGARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRR 60
           MRTDSGARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRR
Sbjct: 1   MRTDSGARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRR 60

Query: 61  PSEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAE 120
           PSEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAE
Sbjct: 61  PSEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAE 120

Query: 121 EAVIQKPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGISQPVGKVF 180
           EAVIQKPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGISQPVGKVF
Sbjct: 121 EAVIQKPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGISQPVGKVF 180

Query: 181 VEKSRRFQAADRSELIKTTENIDVSMDVKPSWTTRDVALTVHRAFRMIGLFSHGFLAGCA 240
           VEKSRRFQAADRSELIKTTENIDVSMDVKPSWTTRDVALTVHRAFRMIGLFSHGFLAGCA
Sbjct: 181 VEKSRRFQAADRSELIKTTENIDVSMDVKPSWTTRDVALTVHRAFRMIGLFSHGFLAGCA 240

Query: 241 VWNIVVIYVLAGDQLSNLSNLLQQYKTLAYPFQSLLYLLLALSTISAFDRIDFAKISVAI 300
           VWNIVVIYVLAGDQLSNLSNLLQQYKTLAYPFQSLLYLLLALSTISAFDRIDFAKISVAI
Sbjct: 241 VWNIVVIYVLAGDQLSNLSNLLQQYKTLAYPFQSLLYLLLALSTISAFDRIDFAKISVAI 300

Query: 301 RNFLALDPTALASFLYFTALILSLSQQMTSDRIHLYTPSSVNGSLWEAGIEEQILQPWIV 360
           RNFLALDPTALASFLYFTALILSLSQQMTSDRIHLYTPSSVNGSLWEAGIEEQILQPWIV
Sbjct: 301 RNFLALDPTALASFLYFTALILSLSQQMTSDRIHLYTPSSVNGSLWEAGIEEQILQPWIV 360

Query: 361 VNLVVALLVGLSWLFLSYRPGMDLSEELMFSSEVEEYPDKEKEIKASS 408
           VNLVVALLVGLSWLFLSYRPGMDLSEELMFSSEVEEYPDKEKEIKASS
Sbjct: 361 VNLVVALLVGLSWLFLSYRPGMDLSEELMFSSEVEEYPDKEKEIKASS 408


>gi|113205077 amyotrophic lateral sclerosis 2 (juvenile) chromosome
           region, candidate 4 isoform b [Homo sapiens]
          Length = 400

 Score =  768 bits (1982), Expect = 0.0
 Identities = 394/395 (99%), Positives = 395/395 (100%)

Query: 14  LRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELK 73
           +RPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELK
Sbjct: 6   VRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELK 65

Query: 74  EHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKK 133
           EHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKK
Sbjct: 66  EHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKK 125

Query: 134 TQPAELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGISQPVGKVFVEKSRRFQAADRS 193
           TQPAELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGISQPVGKVFVEKSRRFQAADRS
Sbjct: 126 TQPAELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGISQPVGKVFVEKSRRFQAADRS 185

Query: 194 ELIKTTENIDVSMDVKPSWTTRDVALTVHRAFRMIGLFSHGFLAGCAVWNIVVIYVLAGD 253
           ELIKTTENIDVSMDVKPSWTTRDVALTVHRAFRMIGLFSHGFLAGCAVWNIVVIYVLAGD
Sbjct: 186 ELIKTTENIDVSMDVKPSWTTRDVALTVHRAFRMIGLFSHGFLAGCAVWNIVVIYVLAGD 245

Query: 254 QLSNLSNLLQQYKTLAYPFQSLLYLLLALSTISAFDRIDFAKISVAIRNFLALDPTALAS 313
           QLSNLSNLLQQYKTLAYPFQSLLYLLLALSTISAFDRIDFAKISVAIRNFLALDPTALAS
Sbjct: 246 QLSNLSNLLQQYKTLAYPFQSLLYLLLALSTISAFDRIDFAKISVAIRNFLALDPTALAS 305

Query: 314 FLYFTALILSLSQQMTSDRIHLYTPSSVNGSLWEAGIEEQILQPWIVVNLVVALLVGLSW 373
           FLYFTALILSLSQQMTSDRIHLYTPSSVNGSLWEAGIEEQILQPWIVVNLVVALLVGLSW
Sbjct: 306 FLYFTALILSLSQQMTSDRIHLYTPSSVNGSLWEAGIEEQILQPWIVVNLVVALLVGLSW 365

Query: 374 LFLSYRPGMDLSEELMFSSEVEEYPDKEKEIKASS 408
           LFLSYRPGMDLSEELMFSSEVEEYPDKEKEIKASS
Sbjct: 366 LFLSYRPGMDLSEELMFSSEVEEYPDKEKEIKASS 400


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 52/234 (22%), Positives = 99/234 (42%), Gaps = 38/234 (16%)

Query: 3   TDSGARLEEGHLRPPRALP-PVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRP 61
           +DS +  E    + P+  P  V +Q   P  +P +  P+  N  A++S    + ++    
Sbjct: 171 SDSSSEDEPPKNQKPKITPVTVKAQTKAP-PKPARAAPKIANGKAASSSSSSSSSSSSDD 229

Query: 62  SEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSL-----------LRN 110
           SE  + +       P+  V ++Q   + P++  T+ T+K SSS              ++N
Sbjct: 230 SEEEKAAAT-----PKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKN 284

Query: 111 ENG-------IDAEPAEEAV-IQKPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQ 162
           + G         A P ++++  Q P++  +K QP E   ++E   ++ D  ++E+     
Sbjct: 285 KPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVE---SSEDSSDESDSSSEEEKKPPT 341

Query: 163 QSVFTAPTGISQPVGKVFVEKSRRFQAADRSELIKTTENIDVSMDVKPSWTTRD 216
           ++V +  T    P  K   E S     +D SE        D     KP+ TT++
Sbjct: 342 KAVVSKAT-TKPPPAKKAAESSSDSSDSDSSE--------DDEAPSKPAGTTKN 386



 Score = 28.9 bits (63), Expect = 8.8
 Identities = 37/174 (21%), Positives = 72/174 (41%), Gaps = 18/174 (10%)

Query: 53  LAQTAGRRPSEGNEPSTKELKEHPEAPVQRRQ----KKTRLPLELETSSTQKKSSSSSLL 108
           +A+ A ++ S  +   + E +E  + P  ++     K+  LP      +  K S SSS  
Sbjct: 74  VAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLP---PGKAAAKASESSSSE 130

Query: 109 RNENGIDAEPAEEAVIQK---PRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQQSV 165
            + +  D E  ++  +QK   P+ K  K  P + + ++     D D  ++++    Q+  
Sbjct: 131 ESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSD----SDSDSSSEDEPPKNQKPK 186

Query: 166 FTAPTGISQ----PVGKVFVEKSRRFQAADRSELIKTTENIDVSMDVKPSWTTR 215
            T  T  +Q    P       K    +AA  S    ++ + D S + K + T +
Sbjct: 187 ITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPK 240


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 7/155 (4%)

Query: 16    PPRALPPVPS--QDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELK 73
             PP  +P VP   ++ +P+  PKK+KP     P         +       +  E    ++ 
Sbjct: 9974  PPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVP 10033

Query: 74    EHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKK 133
             E P+ PV  ++     P ++E    +       L+  E      P  + V   P +  KK
Sbjct: 10034 EVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEK--KPTPVPKKVEAPPPKVPKK 10091

Query: 134   TQPAELQYA---NELGVEDEDIITDEQTTVEQQSV 165
              +P  +  A    E  + +E+I+ +E+   E++ V
Sbjct: 10092 REPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEV 10126



 Score = 28.9 bits (63), Expect = 8.8
 Identities = 34/153 (22%), Positives = 55/153 (35%), Gaps = 25/153 (16%)

Query: 17    PRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEH- 75
             P   P +P     P  +P+ +    K  P       +A      P  G +   K  KE  
Sbjct: 11008 PEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPV-TVPVVGKKAEAKAPKEEA 11066

Query: 76    --PEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKK 133
               P+ P++   KKT  P+E E    +  S              +P +EA        T +
Sbjct: 11067 AKPKGPIKGVPKKTPSPIEAERRKLRPGSGGE-----------KPPDEAPF------TYQ 11109

Query: 134   TQPAELQYANELGVEDEDIITDEQTTVEQQSVF 166
              +   L++  E+    +DII  E   V   ++F
Sbjct: 11110 LKAVPLKFVKEI----KDIILTESEFVGSSAIF 11138


>gi|224458301 family with sequence similarity 186, member A [Homo
            sapiens]
          Length = 2351

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 39/152 (25%), Positives = 65/152 (42%), Gaps = 15/152 (9%)

Query: 63   EGNEPSTKELKEHPEAPVQRRQKKTRLP---LELETSSTQKKSSSSSLLRNENGIDAEPA 119
            E  + +T +  E  E   QR Q++  LP   L+     TQK  +   LL  ENG   +  
Sbjct: 891  EEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQ 950

Query: 120  EEAVIQKPRRKTKKTQPAELQYANELGVED--EDIITDEQTTVE-------QQSVFTAPT 170
            +EA    P R+ +K +  +     E G+ED    I T +Q  ++       ++ V   P 
Sbjct: 951  KEAKHLGPHRRREKGKEKQ---KPERGLEDLERQIKTKDQMQMKETQPKELEKMVIQTPM 1007

Query: 171  GISQPVGKVFVEKSRRFQAADRSELIKTTENI 202
             +S     V  +  R ++  +    +KT EN+
Sbjct: 1008 TLSPRWKSVLKDVQRSYEGKEFQRNLKTLENL 1039


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 45/195 (23%), Positives = 76/195 (38%), Gaps = 22/195 (11%)

Query: 30  PLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEHPEAPVQRRQKKTRL 89
           P S P  KK      P S + + +  T  R P   N+  TK++ E  E   +    + + 
Sbjct: 69  PTSPPSSKKA----PPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ- 123

Query: 90  PLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQK------PRRKTKKTQPAELQYAN 143
               E+SS+   SSSSS +R         A   + +K       + +TKK    +    +
Sbjct: 124 ----ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD 179

Query: 144 ELGV----EDEDIITDEQTTVEQQSVFTAPTGISQPVGKVFVEKSRRFQAADRSELIKTT 199
           E G      D  + T + +T +   V T+P        K    +      +D S+    T
Sbjct: 180 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSP---KITTAKPINPRPSLPPNSDTSKETSLT 236

Query: 200 ENIDVSMDVKPSWTT 214
            N + +++ K + TT
Sbjct: 237 VNKETTVETKETTTT 251



 Score = 32.7 bits (73), Expect = 0.61
 Identities = 45/200 (22%), Positives = 75/200 (37%), Gaps = 28/200 (14%)

Query: 34  PKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEHPEAPVQRRQKKTRLPLEL 93
           PK+  P T   PA  + +G A T  + P+    P+T +      AP +     T+ P   
Sbjct: 721 PKEPAPTTPKEPAPTTPKGTAPTTLKEPA----PTTPK----KPAPKELAPTTTKGP--- 769

Query: 94  ETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKKTQPAELQYANELGVEDEDII 153
            TS+T  K + ++          EPA     +KP   T +T P      +          
Sbjct: 770 -TSTTSDKPAPTTPKETAPTTPKEPA-PTTPKKPAPTTPETPPPTTSEVS------TPTT 821

Query: 154 TDEQTTVEQQSVFTAPTGISQPVGKVFVEKSR-------RFQAADRSELIKTTENIDVSM 206
           T E TT+ +    + P   ++P  K      +       +  AA + E+  T ++     
Sbjct: 822 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 881

Query: 207 DVK--PSWTTRDVALTVHRA 224
           D++  P  TT    +T   A
Sbjct: 882 DLRTTPETTTAAPKMTKETA 901



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 27/121 (22%), Positives = 41/121 (33%), Gaps = 3/121 (2%)

Query: 16  PPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEH 75
           P     P P+      + PK+  P T   PA  + +  A T  + P+     +TK     
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPTT 390

Query: 76  PEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKKTQ 135
           P+ P     KK       E + T  K  + +  +       EPA     +      KK  
Sbjct: 391 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450

Query: 136 P 136
           P
Sbjct: 451 P 451



 Score = 29.6 bits (65), Expect = 5.1
 Identities = 36/162 (22%), Positives = 58/162 (35%), Gaps = 11/162 (6%)

Query: 16  PPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKE--LK 73
           P    P  P +  +  + P+K  P T   PA  + E LA T    P+    P+T E    
Sbjct: 572 PKETAPTTPKK--LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT----PTTPEEPAP 625

Query: 74  EHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKK 133
             P+A      K+       E + T  K  + +  +       +      +++P   T K
Sbjct: 626 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 685

Query: 134 TQPAELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGISQP 175
            +PA  + A     E      D+      +   TAPT   +P
Sbjct: 686 -KPAPKELAPTTTKEPTSTTCDKPAPTTPKG--TAPTTPKEP 724



 Score = 28.9 bits (63), Expect = 8.8
 Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 12/161 (7%)

Query: 22  PVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKE-LKEHPEAPV 80
           P   ++  P + PKK  P T   PA  + +    T  + P+    P+TKE     P+ P 
Sbjct: 388 PTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTTPKEPA 442

Query: 81  QRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKKTQPAELQ 140
               KK       E + T  K  + +  +  +    +       +     TK+  P   +
Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502

Query: 141 YANELGVEDEDIITDE--QTTVEQQSVFT----APTGISQP 175
            A     E     T E   TT ++ +  T    APT   +P
Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 543


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 45/195 (23%), Positives = 76/195 (38%), Gaps = 22/195 (11%)

Query: 30  PLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEHPEAPVQRRQKKTRL 89
           P S P  KK      P S + + +  T  R P   N+  TK++ E  E   +    + + 
Sbjct: 110 PTSPPSSKKA----PPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ- 164

Query: 90  PLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQK------PRRKTKKTQPAELQYAN 143
               E+SS+   SSSSS +R         A   + +K       + +TKK    +    +
Sbjct: 165 ----ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD 220

Query: 144 ELGV----EDEDIITDEQTTVEQQSVFTAPTGISQPVGKVFVEKSRRFQAADRSELIKTT 199
           E G      D  + T + +T +   V T+P        K    +      +D S+    T
Sbjct: 221 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSP---KITTAKPINPRPSLPPNSDTSKETSLT 277

Query: 200 ENIDVSMDVKPSWTT 214
            N + +++ K + TT
Sbjct: 278 VNKETTVETKETTTT 292



 Score = 32.7 bits (73), Expect = 0.61
 Identities = 45/200 (22%), Positives = 75/200 (37%), Gaps = 28/200 (14%)

Query: 34  PKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEHPEAPVQRRQKKTRLPLEL 93
           PK+  P T   PA  + +G A T  + P+    P+T +      AP +     T+ P   
Sbjct: 762 PKEPAPTTPKEPAPTTPKGTAPTTLKEPA----PTTPK----KPAPKELAPTTTKGP--- 810

Query: 94  ETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKKTQPAELQYANELGVEDEDII 153
            TS+T  K + ++          EPA     +KP   T +T P      +          
Sbjct: 811 -TSTTSDKPAPTTPKETAPTTPKEPA-PTTPKKPAPTTPETPPPTTSEVS------TPTT 862

Query: 154 TDEQTTVEQQSVFTAPTGISQPVGKVFVEKSR-------RFQAADRSELIKTTENIDVSM 206
           T E TT+ +    + P   ++P  K      +       +  AA + E+  T ++     
Sbjct: 863 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 922

Query: 207 DVK--PSWTTRDVALTVHRA 224
           D++  P  TT    +T   A
Sbjct: 923 DLRTTPETTTAAPKMTKETA 942



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 27/121 (22%), Positives = 41/121 (33%), Gaps = 3/121 (2%)

Query: 16  PPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEH 75
           P     P P+      + PK+  P T   PA  + +  A T  + P+     +TK     
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPTT 431

Query: 76  PEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKKTQ 135
           P+ P     KK       E + T  K  + +  +       EPA     +      KK  
Sbjct: 432 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491

Query: 136 P 136
           P
Sbjct: 492 P 492



 Score = 29.6 bits (65), Expect = 5.1
 Identities = 36/162 (22%), Positives = 58/162 (35%), Gaps = 11/162 (6%)

Query: 16  PPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKE--LK 73
           P    P  P +  +  + P+K  P T   PA  + E LA T    P+    P+T E    
Sbjct: 613 PKETAPTTPKK--LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT----PTTPEEPAP 666

Query: 74  EHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKK 133
             P+A      K+       E + T  K  + +  +       +      +++P   T K
Sbjct: 667 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 726

Query: 134 TQPAELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGISQP 175
            +PA  + A     E      D+      +   TAPT   +P
Sbjct: 727 -KPAPKELAPTTTKEPTSTTCDKPAPTTPKG--TAPTTPKEP 765



 Score = 28.9 bits (63), Expect = 8.8
 Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 12/161 (7%)

Query: 22  PVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKE-LKEHPEAPV 80
           P   ++  P + PKK  P T   PA  + +    T  + P+    P+TKE     P+ P 
Sbjct: 429 PTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTTPKEPA 483

Query: 81  QRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKKTQPAELQ 140
               KK       E + T  K  + +  +  +    +       +     TK+  P   +
Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543

Query: 141 YANELGVEDEDIITDE--QTTVEQQSVFT----APTGISQP 175
            A     E     T E   TT ++ +  T    APT   +P
Sbjct: 544 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 584


>gi|116268091 PHD finger protein 23 [Homo sapiens]
          Length = 403

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 3/77 (3%)

Query: 15  RPPRALPPVP-SQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELK 73
           RPP AL PVP SQ D  LS P +KK R        +  G       RP+ G+      +K
Sbjct: 159 RPPAALTPVPLSQGD--LSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIK 216

Query: 74  EHPEAPVQRRQKKTRLP 90
           +  +  +++ ++  RLP
Sbjct: 217 KSKKRKLKKAERGDRLP 233


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 39/153 (25%), Positives = 61/153 (39%), Gaps = 13/153 (8%)

Query: 8   RLEEGHLRPPRALPPVPSQDDIPLSRPKKKK---PRTKNTPASASLEGLAQTAGRRPSEG 64
           RL EG L  P  LPP  SQ   P+  P +     P  +  P     +GL Q +G  P++ 
Sbjct: 519 RLLEGSLGEPTPLPPPTSQQP-PVGAPHRASGTSPLKQKGP-----QGLGQPSGPLPAKA 572

Query: 65  NEPSTK----ELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAE 120
           +  STK      K  P+A   R  + ++ P  ++   T+  + +  + +        PA 
Sbjct: 573 SPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPAT 632

Query: 121 EAVIQKPRRKTKKTQPAELQYANELGVEDEDII 153
             V    RR    T   +       G E ED++
Sbjct: 633 PKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLV 665



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 37/164 (22%), Positives = 62/164 (37%), Gaps = 4/164 (2%)

Query: 58   GRRPSEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAE 117
            G  PS   EP   E++    +P  R + +    L   T S    +S +SL   E   D+ 
Sbjct: 951  GPDPSLDREPEL-EMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSS 1009

Query: 118  PAEEAVIQ--KPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGISQP 175
            P+    ++  K +RK +      L    E   E+E++  +E+   EQ+ +        + 
Sbjct: 1010 PSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRS 1069

Query: 176  VGKVFVEKSRRFQAADRSELIKT-TENIDVSMDVKPSWTTRDVA 218
              +         +A  R E  KT   N+    D  P+   R  A
Sbjct: 1070 TARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAA 1113



 Score = 29.6 bits (65), Expect = 5.1
 Identities = 41/156 (26%), Positives = 65/156 (41%), Gaps = 18/156 (11%)

Query: 16   PPRALPPVPS--QDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELK 73
            P R   PV +  ++ +P + P   K      PA A L G    A   P  G+   ++   
Sbjct: 2296 PSRPEMPVGAAREEPLPTTTPAAIK-EAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGF 2354

Query: 74   EHPEAPVQRRQKKTR---LPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRK 130
            E  EA  + RQ+K +   L LE E    +K       LR +  ++ E  E   +Q+ R +
Sbjct: 2355 EKEEASQEERQRKQQEQLLQLERERVELEKLRQ----LRLQEELERERVE---LQRHREE 2407

Query: 131  TKKTQPAELQYANELGVEDEDIITDEQTTVEQQSVF 166
             +     ELQ   EL      ++  +Q   E+Q+ F
Sbjct: 2408 EQLLVQRELQ---ELQTIKHHVLQQQQE--ERQAQF 2438


>gi|58082089 hypothetical protein LOC161394 [Homo sapiens]
          Length = 674

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 40/161 (24%), Positives = 65/161 (40%), Gaps = 28/161 (17%)

Query: 6   GARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSE-G 64
           G  LEE  L+PP+   P   ++     R   +K RT+  P  A LE L +   +   E G
Sbjct: 222 GESLEETDLQPPKMTKPETPEET---QRESTEKKRTE-PPEQARLEFLEKEPRKSSEEAG 277

Query: 65  NEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVI 124
            EP  +   E PE              E++  +T++K +          +      +   
Sbjct: 278 LEPPEETQPEVPE--------------EMQRKATEEKGTE---------LPERTKPDFPD 314

Query: 125 QKPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQQSV 165
            KPR+ T +  P  L+       E+E   T+E+T +EQ  +
Sbjct: 315 HKPRKSTDENVPEPLEEIKLEFPEEESRKTNEETILEQSEM 355


>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
          Length = 1123

 Score = 37.7 bits (86), Expect = 0.019
 Identities = 43/159 (27%), Positives = 64/159 (40%), Gaps = 26/159 (16%)

Query: 2   RTDSGARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAG--- 58
           R  S  RL + H+R   A P           R +KKK R ++T ASA  EG  Q      
Sbjct: 822 RLGSETRLPQ-HIREATAAPHG--------KRKRKKKKRPEDTAASALQEGQTQRQPGSP 872

Query: 59  --RRPSEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDA 116
             RR  +   P+ +  +E    P    Q+   +      SS +++   +  L  E G+  
Sbjct: 873 MYRREGQAQLPAVRR-QEDGTQPQVNGQQVGCVTDGHHASSRKRRRKGAEGLGEEGGLHQ 931

Query: 117 EPAE-----------EAVIQKPRRKTKKTQPAELQYANE 144
           +P             EA+ + PR+K KK +  E Q A E
Sbjct: 932 DPLRHSCSPMGDGDPEAMEESPRKKKKKKRKQETQRAVE 970


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 22/109 (20%), Positives = 51/109 (46%), Gaps = 1/109 (0%)

Query: 54   AQTAGRRPSEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENG 113
            A ++    +E  EP  +E +E P    ++RQ +     ELE    +++  +++     + 
Sbjct: 1255 ADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQ-ELEEPEPEEEEDAAAETAQNDD 1313

Query: 114  IDAEPAEEAVIQKPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQ 162
             DA+  ++  ++  ++K  + QP       E GV++  +  + Q + E+
Sbjct: 1314 HDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREK 1362



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 32/132 (24%), Positives = 48/132 (36%), Gaps = 2/132 (1%)

Query: 4    DSGARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSE 63
            DS   LEE    P         + +    +  + + +   +    S +G      RR SE
Sbjct: 883  DSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSE 942

Query: 64   GNEPSTKELKEHPEA-PVQRRQKKTRLPLEL-ETSSTQKKSSSSSLLRNENGIDAEPAEE 121
            G EP   +LK+ PEA   +  +   RLP    E      +  S S    E       +  
Sbjct: 943  GVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSP 1002

Query: 122  AVIQKPRRKTKK 133
             ++ KP  K KK
Sbjct: 1003 PILTKPTLKRKK 1014


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 22/109 (20%), Positives = 51/109 (46%), Gaps = 1/109 (0%)

Query: 54   AQTAGRRPSEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENG 113
            A ++    +E  EP  +E +E P    ++RQ +     ELE    +++  +++     + 
Sbjct: 1255 ADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQ-ELEEPEPEEEEDAAAETAQNDD 1313

Query: 114  IDAEPAEEAVIQKPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQ 162
             DA+  ++  ++  ++K  + QP       E GV++  +  + Q + E+
Sbjct: 1314 HDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREK 1362



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 32/132 (24%), Positives = 48/132 (36%), Gaps = 2/132 (1%)

Query: 4    DSGARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSE 63
            DS   LEE    P         + +    +  + + +   +    S +G      RR SE
Sbjct: 883  DSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSE 942

Query: 64   GNEPSTKELKEHPEA-PVQRRQKKTRLPLEL-ETSSTQKKSSSSSLLRNENGIDAEPAEE 121
            G EP   +LK+ PEA   +  +   RLP    E      +  S S    E       +  
Sbjct: 943  GVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSP 1002

Query: 122  AVIQKPRRKTKK 133
             ++ KP  K KK
Sbjct: 1003 PILTKPTLKRKK 1014


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 22/109 (20%), Positives = 51/109 (46%), Gaps = 1/109 (0%)

Query: 54   AQTAGRRPSEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENG 113
            A ++    +E  EP  +E +E P    ++RQ +     ELE    +++  +++     + 
Sbjct: 1255 ADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQ-ELEEPEPEEEEDAAAETAQNDD 1313

Query: 114  IDAEPAEEAVIQKPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQ 162
             DA+  ++  ++  ++K  + QP       E GV++  +  + Q + E+
Sbjct: 1314 HDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREK 1362



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 32/132 (24%), Positives = 48/132 (36%), Gaps = 2/132 (1%)

Query: 4    DSGARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSE 63
            DS   LEE    P         + +    +  + + +   +    S +G      RR SE
Sbjct: 883  DSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSE 942

Query: 64   GNEPSTKELKEHPEA-PVQRRQKKTRLPLEL-ETSSTQKKSSSSSLLRNENGIDAEPAEE 121
            G EP   +LK+ PEA   +  +   RLP    E      +  S S    E       +  
Sbjct: 943  GVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSP 1002

Query: 122  AVIQKPRRKTKK 133
             ++ KP  K KK
Sbjct: 1003 PILTKPTLKRKK 1014


>gi|61097912 nucleolar protein with MIF4G domain 1 [Homo sapiens]
          Length = 860

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 44/189 (23%), Positives = 77/189 (40%), Gaps = 36/189 (19%)

Query: 5   SGARLEEGHLRPPRALP-PVPSQDDIPLSRPKKKKPRTKNTPASASLE-GLAQTAGRRPS 62
           SGA    GH +       P PS+D  P  +P+  + + K T A+A      A TA  R  
Sbjct: 114 SGAEEASGHRQDTEERARPAPSRDPSPPRKPRPSRVKAKATAATAKTRPSAAATAAARKR 173

Query: 63  ---EGNEPSTKELKEHPEA-PVQRRQKK---TRLPLEL---------------------E 94
                NE   +E+++      + +R+KK   + +PL                       +
Sbjct: 174 ALLAANEEEDREIRKLERCLGLNKRKKKDGSSSVPLSFARDGLDYILGALESGKNSGLYD 233

Query: 95  TSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKKTQPAELQYANELGVEDEDIIT 154
           +S  +++ +  +L  ++   D++   E   +    K KK Q AE Q       ED+D  T
Sbjct: 234 SSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQ------SEDDDEDT 287

Query: 155 DEQTTVEQQ 163
           +E+   E++
Sbjct: 288 EEEQGEEKE 296


>gi|89886237 cyclin I family, member 2 [Homo sapiens]
          Length = 369

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 7/99 (7%)

Query: 6   GARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGN 65
           GA LEE  L  P  LPP P +  +P S  + + P T+  P +ASL   +     RP  G 
Sbjct: 27  GAGLEETALGVP--LPPSPGEAPLPRSN-RSRCPGTRQ-PGAASLHAASAAVPVRPRRGT 82

Query: 66  EPSTKELKEHPEAPVQ---RRQKKTRLPLELETSSTQKK 101
            P+ K     P A  +   R   ++R P  LE    +++
Sbjct: 83  APAGKTADAVPAAAPEQAPRPAPQSRKPRNLEGDLDERR 121


>gi|24497513 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 36.6 bits (83), Expect = 0.042
 Identities = 35/128 (27%), Positives = 47/128 (36%), Gaps = 11/128 (8%)

Query: 13  HLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKEL 72
           H  PP+A PP P Q   P  +P    P     P+SAS     Q A   P+  N   +  L
Sbjct: 91  HPPPPQAAPPAP-QPPQPAPQPPAPTPAAPPPPSSAS---PPQNASNNPTPANAAKSPLL 146

Query: 73  KEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTK 132
                A       K   P   E+    K+ +SSS        D  P  +A  ++ R    
Sbjct: 147 NSPTVA-------KQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYT 199

Query: 133 KTQPAELQ 140
             Q  EL+
Sbjct: 200 SAQLVELE 207


>gi|13562112 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 36.6 bits (83), Expect = 0.042
 Identities = 35/128 (27%), Positives = 47/128 (36%), Gaps = 11/128 (8%)

Query: 13  HLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKEL 72
           H  PP+A PP P Q   P  +P    P     P+SAS     Q A   P+  N   +  L
Sbjct: 91  HPPPPQAAPPAP-QPPQPAPQPPAPTPAAPPPPSSAS---PPQNASNNPTPANAAKSPLL 146

Query: 73  KEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTK 132
                A       K   P   E+    K+ +SSS        D  P  +A  ++ R    
Sbjct: 147 NSPTVA-------KQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYT 199

Query: 133 KTQPAELQ 140
             Q  EL+
Sbjct: 200 SAQLVELE 207


>gi|118498364 dapper 1 isoform 2 [Homo sapiens]
          Length = 799

 Score = 36.6 bits (83), Expect = 0.042
 Identities = 55/230 (23%), Positives = 86/230 (37%), Gaps = 43/230 (18%)

Query: 5   SGARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPAS---ASLEGLAQTAGRRP 61
           S   LEE HL   + +P    Q  + L R  +     KN+       +L+GL        
Sbjct: 508 SSQSLEEAHLVKAQFIPG--QQPSVRLHRGHRNMGVVKNSSLKHRGPALQGL-------- 557

Query: 62  SEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRN---ENGIDAEP 118
            E   P+ +E         +   KK R P +L+T+   KK+SS         E G+   P
Sbjct: 558 -ENGLPTVRE-------KTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRP 609

Query: 119 A--------------EEAVIQKPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQQS 164
           A               EAV+ KP  K K+T     + + E+  E E +    +   E   
Sbjct: 610 AGGGHRAGSRAHGHGREAVVAKP--KHKRTDYRRWKSSAEISYE-EALRRARRGRRENVG 666

Query: 165 VFTAPTGISQPVGKVFVEKSRRFQAADRSELIKTTENIDVSMDVKPSWTT 214
           ++ AP  +       +V     + A   S    T   +D S D + ++TT
Sbjct: 667 LYPAPVPLPYASPYAYVASDSEYSAECESLFHSTV--VDTSEDEQSNYTT 714


>gi|24158478 dapper 1 isoform 1 [Homo sapiens]
          Length = 836

 Score = 36.6 bits (83), Expect = 0.042
 Identities = 55/230 (23%), Positives = 86/230 (37%), Gaps = 43/230 (18%)

Query: 5   SGARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPAS---ASLEGLAQTAGRRP 61
           S   LEE HL   + +P    Q  + L R  +     KN+       +L+GL        
Sbjct: 545 SSQSLEEAHLVKAQFIPG--QQPSVRLHRGHRNMGVVKNSSLKHRGPALQGL-------- 594

Query: 62  SEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRN---ENGIDAEP 118
            E   P+ +E         +   KK R P +L+T+   KK+SS         E G+   P
Sbjct: 595 -ENGLPTVRE-------KTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRP 646

Query: 119 A--------------EEAVIQKPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQQS 164
           A               EAV+ KP  K K+T     + + E+  E E +    +   E   
Sbjct: 647 AGGGHRAGSRAHGHGREAVVAKP--KHKRTDYRRWKSSAEISYE-EALRRARRGRRENVG 703

Query: 165 VFTAPTGISQPVGKVFVEKSRRFQAADRSELIKTTENIDVSMDVKPSWTT 214
           ++ AP  +       +V     + A   S    T   +D S D + ++TT
Sbjct: 704 LYPAPVPLPYASPYAYVASDSEYSAECESLFHSTV--VDTSEDEQSNYTT 751


>gi|114842410 zinc finger CCCH-type containing 11A [Homo sapiens]
          Length = 810

 Score = 36.6 bits (83), Expect = 0.042
 Identities = 46/194 (23%), Positives = 74/194 (38%), Gaps = 20/194 (10%)

Query: 30  PLSRPKKKKPRTKNTPASASLE---------GLAQTAGRRPSEGNEPSTKELKEHPEAPV 80
           P+  P+K+  RT     + S +          L +  G+R       S   LK    +  
Sbjct: 248 PVPGPEKENVRTVVRTVTLSTKQGEEPLVRLSLTERLGKRKFSAGGDSDPPLKR---SLA 304

Query: 81  QRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRR----KTKKTQP 136
           QR  KK   P E     T KK+  S  L+   G+ A+P  E    K  +      K  + 
Sbjct: 305 QRLGKKVEAP-ETNIDKTPKKAQVSKSLKERLGMSADPDNEDATDKVNKVGEIHVKTLEE 363

Query: 137 AELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGIS---QPVGKVFVEKSRRFQAADRS 193
             L+ A++   E +  +  E  +    S   A +  +   +   +V  EK  R Q A+R 
Sbjct: 364 ILLERASQKRGELQTKLKTEGPSKTDDSTSGARSSSTIRIKTFSEVLAEKKHRQQEAERQ 423

Query: 194 ELIKTTENIDVSMD 207
           +  K T  I + +D
Sbjct: 424 KSKKDTTCIKLKID 437


>gi|169204941 PREDICTED: similar to Nucleolar protein 5A [Homo
           sapiens]
          Length = 166

 Score = 36.2 bits (82), Expect = 0.055
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 2/107 (1%)

Query: 17  PRALPPVPSQD-DIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEH 75
           P+ +P   ++D  I  S+PKKKK  +K    S+ LE  A +      + + P T+ + + 
Sbjct: 60  PQEVPQEKTEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSLLKRKKSSPKTETVNDP 119

Query: 76  PEAPVQR-RQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEE 121
            EA  +   +KKT+   E   SS  ++++ S     +     E  E+
Sbjct: 120 EEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSSSKKKMFHKEAQED 166


>gi|169205573 PREDICTED: similar to Nucleolar protein 5A [Homo
           sapiens]
          Length = 166

 Score = 36.2 bits (82), Expect = 0.055
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 2/107 (1%)

Query: 17  PRALPPVPSQD-DIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEH 75
           P+ +P   ++D  I  S+PKKKK  +K    S+ LE  A +      + + P T+ + + 
Sbjct: 60  PQEVPQEKTEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSLLKRKKSSPKTETVNDP 119

Query: 76  PEAPVQR-RQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEE 121
            EA  +   +KKT+   E   SS  ++++ S     +     E  E+
Sbjct: 120 EEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSSSKKKMFHKEAQED 166


>gi|169203848 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 166

 Score = 36.2 bits (82), Expect = 0.055
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 2/107 (1%)

Query: 17  PRALPPVPSQD-DIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEH 75
           P+ +P   ++D  I  S+PKKKK  +K    S+ LE  A +      + + P T+ + + 
Sbjct: 60  PQEVPQEKTEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSLLKRKKSSPKTETVNDP 119

Query: 76  PEAPVQR-RQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEE 121
            EA  +   +KKT+   E   SS  ++++ S     +     E  E+
Sbjct: 120 EEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSSSKKKMFHKEAQED 166


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 36.2 bits (82), Expect = 0.055
 Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 2/73 (2%)

Query: 70  KELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRR 129
           K+++E  +   Q  +++TR  LELE    + +S +  L +     +AE A+EA++Q  R 
Sbjct: 352 KQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQ--EAEEAKEALLQASRD 409

Query: 130 KTKKTQPAELQYA 142
           + K  +   L+ A
Sbjct: 410 QKKTQEQLALEMA 422


>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
           sapiens]
          Length = 486

 Score = 36.2 bits (82), Expect = 0.055
 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 22/148 (14%)

Query: 2   RTDSGARLEEGHLRPPRA-LPPVPSQ------DDIPLSRPKKKKPRTKNTPASASLEGLA 54
           + D   +  E  ++P    +P  P +      +D+P S  K  +P+  N P S S + + 
Sbjct: 33  KQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKS-SAKPIQ 91

Query: 55  QTAGRRPSEGNEPSTKELKEHPEAPVQRRQ-KKTRLPLELETSSTQKKSSSSSLLRNENG 113
              G  P    +PS  +  + P+AP +  Q KK  LP          KSS  ++   E  
Sbjct: 92  PKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLP----------KSSEEAIQPKEGD 141

Query: 114 I---DAEPAEEAVIQKPRRKTKKTQPAE 138
           I    A+P +  +    +   K +QP E
Sbjct: 142 IPKSSAKPIQPKLGNIAKTSVKPSQPKE 169



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 46/216 (21%), Positives = 84/216 (38%), Gaps = 34/216 (15%)

Query: 24  PSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAG---RRPSEGNEPSTKELKEHPEAPV 80
           P + DIP S  K  +P+  N P  AS++      G   + P E  +P   +L +  E  +
Sbjct: 182 PKEGDIPKSSAKPIQPKLGNIP-KASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAI 240

Query: 81  QRRQ-------------KKTRLPLELETSSTQKK----SSSSSLLRNENGIDAEPAEEAV 123
           Q ++             K+  +P  LE +   K+     S    ++ + G   +  EEA+
Sbjct: 241 QPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAI 300

Query: 124 IQK----PRRKTKKTQPAELQYANEL----GVEDEDIITDEQTTV---EQQSVFTAPTGI 172
             K    P+   +  QP E      L      ++ DI    + T+   E  S  +     
Sbjct: 301 QPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEAT 360

Query: 173 SQPVGKVF--VEKSRRFQAADRSELIKTTENIDVSM 206
               G +    E++  F   D+ ++I + E+ + S+
Sbjct: 361 PSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASL 396


>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
           sapiens]
          Length = 553

 Score = 36.2 bits (82), Expect = 0.055
 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 22/148 (14%)

Query: 2   RTDSGARLEEGHLRPPRA-LPPVPSQ------DDIPLSRPKKKKPRTKNTPASASLEGLA 54
           + D   +  E  ++P    +P  P +      +D+P S  K  +P+  N P S S + + 
Sbjct: 100 KQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKS-SAKPIQ 158

Query: 55  QTAGRRPSEGNEPSTKELKEHPEAPVQRRQ-KKTRLPLELETSSTQKKSSSSSLLRNENG 113
              G  P    +PS  +  + P+AP +  Q KK  LP          KSS  ++   E  
Sbjct: 159 PKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLP----------KSSEEAIQPKEGD 208

Query: 114 I---DAEPAEEAVIQKPRRKTKKTQPAE 138
           I    A+P +  +    +   K +QP E
Sbjct: 209 IPKSSAKPIQPKLGNIAKTSVKPSQPKE 236



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 46/216 (21%), Positives = 84/216 (38%), Gaps = 34/216 (15%)

Query: 24  PSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAG---RRPSEGNEPSTKELKEHPEAPV 80
           P + DIP S  K  +P+  N P  AS++      G   + P E  +P   +L +  E  +
Sbjct: 249 PKEGDIPKSSAKPIQPKLGNIP-KASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAI 307

Query: 81  QRRQ-------------KKTRLPLELETSSTQKK----SSSSSLLRNENGIDAEPAEEAV 123
           Q ++             K+  +P  LE +   K+     S    ++ + G   +  EEA+
Sbjct: 308 QPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAI 367

Query: 124 IQK----PRRKTKKTQPAELQYANEL----GVEDEDIITDEQTTV---EQQSVFTAPTGI 172
             K    P+   +  QP E      L      ++ DI    + T+   E  S  +     
Sbjct: 368 QPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEAT 427

Query: 173 SQPVGKVF--VEKSRRFQAADRSELIKTTENIDVSM 206
               G +    E++  F   D+ ++I + E+ + S+
Sbjct: 428 PSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASL 463


>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
           sapiens]
          Length = 486

 Score = 36.2 bits (82), Expect = 0.055
 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 22/148 (14%)

Query: 2   RTDSGARLEEGHLRPPRA-LPPVPSQ------DDIPLSRPKKKKPRTKNTPASASLEGLA 54
           + D   +  E  ++P    +P  P +      +D+P S  K  +P+  N P S S + + 
Sbjct: 33  KQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKS-SAKPIQ 91

Query: 55  QTAGRRPSEGNEPSTKELKEHPEAPVQRRQ-KKTRLPLELETSSTQKKSSSSSLLRNENG 113
              G  P    +PS  +  + P+AP +  Q KK  LP          KSS  ++   E  
Sbjct: 92  PKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLP----------KSSEEAIQPKEGD 141

Query: 114 I---DAEPAEEAVIQKPRRKTKKTQPAE 138
           I    A+P +  +    +   K +QP E
Sbjct: 142 IPKSSAKPIQPKLGNIAKTSVKPSQPKE 169



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 46/216 (21%), Positives = 84/216 (38%), Gaps = 34/216 (15%)

Query: 24  PSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAG---RRPSEGNEPSTKELKEHPEAPV 80
           P + DIP S  K  +P+  N P  AS++      G   + P E  +P   +L +  E  +
Sbjct: 182 PKEGDIPKSSAKPIQPKLGNIP-KASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAI 240

Query: 81  QRRQ-------------KKTRLPLELETSSTQKK----SSSSSLLRNENGIDAEPAEEAV 123
           Q ++             K+  +P  LE +   K+     S    ++ + G   +  EEA+
Sbjct: 241 QPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAI 300

Query: 124 IQK----PRRKTKKTQPAELQYANEL----GVEDEDIITDEQTTV---EQQSVFTAPTGI 172
             K    P+   +  QP E      L      ++ DI    + T+   E  S  +     
Sbjct: 301 QPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEAT 360

Query: 173 SQPVGKVF--VEKSRRFQAADRSELIKTTENIDVSM 206
               G +    E++  F   D+ ++I + E+ + S+
Sbjct: 361 PSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASL 396


>gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]
          Length = 1531

 Score = 35.8 bits (81), Expect = 0.072
 Identities = 49/199 (24%), Positives = 78/199 (39%), Gaps = 30/199 (15%)

Query: 15   RPPRALPPVPSQDDIPLSRPKKKKPRTKNTPAS-----ASLEGLAQTAGRRPSEGNEPST 69
            R  R +P +  +      +  KKK + +NT  S       LEGL Q   ++  +  EP T
Sbjct: 1215 RGQRVIPRITIEMKAEAEKKNKKKIKNENTEGSPQEDGVELEGLKQRLEKK--QKREPGT 1272

Query: 70   KELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRR 129
            K  K+   A    ++ K R P            S S    +E+  D  P E     +PRR
Sbjct: 1273 KTKKQTTLAFKPIKKGKKRNPW---------SDSESDRSSDESNFDVPPRE----TEPRR 1319

Query: 130  KTKKTQPAELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGISQPVGKVFVEKSRRFQA 189
               KT     ++  +L   DED    ++ T ++  V   P+  S P  K   + S + + 
Sbjct: 1320 AATKT-----KFTMDLD-SDEDFSDFDEKTDDEDFV---PSDASPPKTKTSPKLSNK-EL 1369

Query: 190  ADRSELIKTTENIDVSMDV 208
              +  ++   E  DV   V
Sbjct: 1370 KPQKSVVSDLEADDVKGSV 1388


>gi|148839382 ring finger protein 169 [Homo sapiens]
          Length = 708

 Score = 35.8 bits (81), Expect = 0.072
 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 5/93 (5%)

Query: 25  SQDDIP-LSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEHPEAPVQRR 83
           S++ +P L R +K+  +TK+   + SL+ L QT+G       +P  +E+++  +   + R
Sbjct: 611 SEEPLPSLRRGRKRHCKTKHLEQNGSLKKLRQTSGEVGLAPTDPVLREMEQKLQQEEEDR 670

Query: 84  QKKTRLPL----ELETSSTQKKSSSSSLLRNEN 112
           Q   +L      E  T S +K S    LLR+ N
Sbjct: 671 QLALQLQRMFDNERRTVSRRKGSVDQYLLRSSN 703


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,344,725
Number of Sequences: 37866
Number of extensions: 699647
Number of successful extensions: 3666
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 271
Number of HSP's that attempted gapping in prelim test: 3298
Number of HSP's gapped (non-prelim): 590
length of query: 408
length of database: 18,247,518
effective HSP length: 105
effective length of query: 303
effective length of database: 14,271,588
effective search space: 4324291164
effective search space used: 4324291164
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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