BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|18105018 acetylcholinesterase collagen-like tail subunit isoform II [Homo sapiens] (445 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|18105018 acetylcholinesterase collagen-like tail subunit isof... 976 0.0 gi|18105016 acetylcholinesterase collagen-like tail subunit isof... 927 0.0 gi|145701009 acetylcholinesterase collagen-like tail subunit iso... 840 0.0 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 200 2e-51 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 200 2e-51 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 200 2e-51 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 199 6e-51 gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 198 9e-51 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 195 6e-50 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 194 2e-49 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 193 2e-49 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 193 2e-49 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 192 5e-49 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 192 7e-49 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 191 1e-48 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 191 1e-48 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 190 3e-48 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 188 7e-48 gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] 188 7e-48 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 188 1e-47 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 188 1e-47 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 188 1e-47 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 188 1e-47 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 187 1e-47 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 187 1e-47 gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 186 4e-47 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 186 4e-47 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 186 4e-47 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 186 4e-47 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 186 5e-47 >gi|18105018 acetylcholinesterase collagen-like tail subunit isoform II [Homo sapiens] Length = 445 Score = 976 bits (2522), Expect = 0.0 Identities = 445/445 (100%), Positives = 445/445 (100%) Query: 1 MTGSSFSLAHLLIISGLLCYSAGCLALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGG 60 MTGSSFSLAHLLIISGLLCYSAGCLALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGG Sbjct: 1 MTGSSFSLAHLLIISGLLCYSAGCLALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGG 60 Query: 61 RSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGR 120 RSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGR Sbjct: 61 RSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGR 120 Query: 121 KGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE 180 KGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE Sbjct: 121 KGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE 180 Query: 181 KGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGP 240 KGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGP Sbjct: 181 KGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGP 240 Query: 241 PGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYG 300 PGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYG Sbjct: 241 PGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYG 300 Query: 301 PSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTAD 360 PSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTAD Sbjct: 301 PSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTAD 360 Query: 361 QHGTCGDGLLQPGEECDDGNSDVGDDCIRCHRAYCGDGHRHEGVEDCDGSDFGYLTCETY 420 QHGTCGDGLLQPGEECDDGNSDVGDDCIRCHRAYCGDGHRHEGVEDCDGSDFGYLTCETY Sbjct: 361 QHGTCGDGLLQPGEECDDGNSDVGDDCIRCHRAYCGDGHRHEGVEDCDGSDFGYLTCETY 420 Query: 421 LPGSYGDLQCTQYCYIDSTPCRYFT 445 LPGSYGDLQCTQYCYIDSTPCRYFT Sbjct: 421 LPGSYGDLQCTQYCYIDSTPCRYFT 445 >gi|18105016 acetylcholinesterase collagen-like tail subunit isoform I precursor [Homo sapiens] Length = 455 Score = 927 bits (2395), Expect = 0.0 Identities = 420/420 (100%), Positives = 420/420 (100%) Query: 26 ALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQ 85 ALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQ Sbjct: 36 ALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQ 95 Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR Sbjct: 96 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 155 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM Sbjct: 156 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 215 Query: 206 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLI 265 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLI Sbjct: 216 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLI 275 Query: 266 MGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQN 325 MGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQN Sbjct: 276 MGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQN 335 Query: 326 AIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGD 385 AIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGD Sbjct: 336 AIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGD 395 Query: 386 DCIRCHRAYCGDGHRHEGVEDCDGSDFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT 445 DCIRCHRAYCGDGHRHEGVEDCDGSDFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT Sbjct: 396 DCIRCHRAYCGDGHRHEGVEDCDGSDFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT 455 >gi|145701009 acetylcholinesterase collagen-like tail subunit isoform III precursor [Homo sapiens] Length = 421 Score = 840 bits (2169), Expect = 0.0 Identities = 386/420 (91%), Positives = 386/420 (91%), Gaps = 34/420 (8%) Query: 26 ALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQ 85 ALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSP Sbjct: 36 ALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSP---------------------- 73 Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 GPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR Sbjct: 74 ------------GPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 121 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM Sbjct: 122 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 181 Query: 206 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLI 265 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLI Sbjct: 182 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLI 241 Query: 266 MGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQN 325 MGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQN Sbjct: 242 MGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQN 301 Query: 326 AIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGD 385 AIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGD Sbjct: 302 AIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGD 361 Query: 386 DCIRCHRAYCGDGHRHEGVEDCDGSDFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT 445 DCIRCHRAYCGDGHRHEGVEDCDGSDFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT Sbjct: 362 DCIRCHRAYCGDGHRHEGVEDCDGSDFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT 421 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 200 bits (508), Expect = 2e-51 Identities = 117/267 (43%), Positives = 136/267 (50%), Gaps = 45/267 (16%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEG 143 +QG +G PGP GP GPPG G G GE G+ G G KG GPPG G GPIG PGP G Sbjct: 1136 LQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG 1195 Query: 144 ------PRGE------KGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP----- 186 PRG+ KGD G G PG GP+G +G PG GEKG G+ G +GP Sbjct: 1196 ADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG 1255 Query: 187 -KGEKGFPGF------------PGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKG 233 +G G PG PG +G+KGE G GEPG+ G GP G G+RG++G+ G Sbjct: 1256 PRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESG 1315 Query: 234 DSGVMGPPG------------KPGPSGQPGRPGPPGPP-PAGQLIMGPKGERGFPGPPGR 280 SG GPPG PGP G PG PGPPG P PAGQ GP G++G G PG+ Sbjct: 1316 PSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQ--DGPPGDKGDDGEPGQ 1373 Query: 281 CLCGPTMNVNNPSYGESVYGPSSPRVP 307 PS GP P P Sbjct: 1374 TGSPGPTGEPGPSGPPGKRGPPGPAGP 1400 Score = 199 bits (506), Expect = 4e-51 Identities = 103/212 (48%), Positives = 122/212 (57%), Gaps = 19/212 (8%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRP---GRKGRPGPPGVPGMPGPIGWPGPE 142 G +G PGPPGP+GP G PG GP+G G +G P G KG PG G PG+PG G PGP+ Sbjct: 1246 GQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPK 1305 Query: 143 GPRGEKGDLGMMGL---------------PGSRGPMGSKGYPGSRGEKGSRGEKGDLGPK 187 G RGEKG+ G G GS GP+G G PG GE G G+ G G K Sbjct: 1306 GERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDK 1365 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPS 247 G+ G PG G G GE GP G PG G GP G G++G++G KG++G+ GPPGK GP Sbjct: 1366 GDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPI 1425 Query: 248 GQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G G PG PGP + I GP GE+G PG PG Sbjct: 1426 GPQGAPGKPGPDGL-RGIPGPVGEQGLPGSPG 1456 Score = 191 bits (486), Expect = 9e-49 Identities = 106/228 (46%), Positives = 116/228 (50%), Gaps = 29/228 (12%) Query: 81 SPCMQGSLGSPGPPGPQGPPGL---PGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIG 137 SP G G PGPPG GP G PG G GE G+ G PG G PGP G PG GP G Sbjct: 1337 SPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPG 1396 Query: 138 WPGPEGPRGEK---------------GDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKG 182 GPEG +GEK G +G G PG GP G +G PG GE+G G G Sbjct: 1397 PAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPG 1456 Query: 183 DLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGR---------PGKRGKQGQKG 233 GP G G PG PG+ G G G KG PG+ G GP G PG +G G KG Sbjct: 1457 PDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKG 1516 Query: 234 DSGVMGPPGKPGPSGQPGRPGPPGPPPA--GQLIMGPKGERGFPGPPG 279 + G+ GP G GP G PG PGPPGP A GPKGE G PGPPG Sbjct: 1517 EQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPG 1564 Score = 189 bits (479), Expect = 6e-48 Identities = 103/229 (44%), Positives = 117/229 (51%), Gaps = 35/229 (15%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP---- 141 G +G PG PGP G PG G+ GP G+KG+ G PG+ G PGP G PG GP G GP Sbjct: 1339 GPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPA 1398 Query: 142 -----------------EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL 184 EGP G+ G +G G PG GP G +G PG GE+G G G Sbjct: 1399 GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPD 1458 Query: 185 GPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGR---------PGKRGKQGQKGDS 235 GP G G PG PG+ G G G KG PG+ G GP G PG +G G KG+ Sbjct: 1459 GPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ 1518 Query: 236 GVMGPPGKPGPSGQPGRPGPPGPPPA--GQLIMGPKGERGF---PGPPG 279 G+ GP G GP G PG PGPPGP A GPKGE G PGPPG Sbjct: 1519 GITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPG 1567 Score = 187 bits (475), Expect = 2e-47 Identities = 97/196 (49%), Positives = 116/196 (59%), Gaps = 5/196 (2%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G +G PG PGPQGPPG G+ G GEKG G GR G GP G+PG GP+G PG +G Sbjct: 1099 GPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDG-- 1156 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 +KG++G G GS+G G +G PG G +G G+ G G GE G G G+ GQKG+ Sbjct: 1157 -DKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDE 1215 Query: 206 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP--PPAGQ 263 GP+G PG G G G PG G++G+ GD G MGPPG PGP G G PG GP PP G Sbjct: 1216 GPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGI 1275 Query: 264 LIMGPKGERGFPGPPG 279 G GE+G PG G Sbjct: 1276 GNPGAVGEKGEPGEAG 1291 Score = 186 bits (473), Expect = 3e-47 Identities = 101/224 (45%), Positives = 123/224 (54%), Gaps = 30/224 (13%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEG 143 ++G G+ G G G PG G G KG++GE+G PG +G GP G G GP G PGP G Sbjct: 800 IRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLG 859 Query: 144 PRGEKGDLGMMGLP------GSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPG 197 P GEKG LG+ GLP G +G +G G+PG+ GEKG RG G GP+G++G G G Sbjct: 860 PPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRG 919 Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRP---- 253 G +G G G G +G GP G PG+RG G +G +G GP G PGP G+ G P Sbjct: 920 ERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPG 979 Query: 254 -----------GPPGPP-------PAGQLIMGPKGERGFPGPPG 279 GPPGPP P G+ GP GERG PGPPG Sbjct: 980 QRGETGFQGKTGPPGPPGVVGPQGPTGE--TGPMGERGHPGPPG 1021 Score = 186 bits (471), Expect = 5e-47 Identities = 104/220 (47%), Positives = 116/220 (52%), Gaps = 22/220 (10%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G PGPPG QG PG G GP+G G G G G+PG PG+PG GP G PG EGP Sbjct: 712 GPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPP 771 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 GEKG G PG +GP+G G G +G G RG KG G KGE GFPGF G +G KG+ Sbjct: 772 GEKGG---QGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR 828 Query: 206 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLI 265 G G PG G GP G +G+ G GD G +GPPG+ G G PG PG PG Sbjct: 829 GEIGPPGPRGEDGP---EGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGR------- 878 Query: 266 MGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 GPKG GFPG PG N G G PR Sbjct: 879 QGPKGSIGFPGFPG---------ANGEKGGRGTPGKPGPR 909 Score = 185 bits (470), Expect = 6e-47 Identities = 110/270 (40%), Positives = 135/270 (50%), Gaps = 34/270 (12%) Query: 44 LTPPPPPLFPPPFFRGG------RSPLLSPDMKNLMLELETSQSPCM--QGSLGSPGPPG 95 L PP + PF GG + P++S L+ ++ G +G G PG Sbjct: 512 LPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPG 571 Query: 96 PQGPPGL------PGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKG 149 P GPPG PG GP+G +G G PG G+PG G G G G PG GP+G++G Sbjct: 572 PVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRG 631 Query: 150 DLGMMGLPGSRG------PMGSKGYPGSRGEKGSRGE------------KGDLGPKGEKG 191 G+ GLPG +G P G G PG GE+G GE +G LGPKG G Sbjct: 632 FDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPG 691 Query: 192 FPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPG 251 PG PG+ G G+ GPKG G G GP G+ G G QG G G +GPPG+ GP G+PG Sbjct: 692 PPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPG 751 Query: 252 RPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 PG PG PP GP GE+G GPPG Sbjct: 752 LPGMPGADGPPGHPGKEGPPGEKGGQGPPG 781 Score = 184 bits (468), Expect = 1e-46 Identities = 114/266 (42%), Positives = 133/266 (50%), Gaps = 41/266 (15%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 P P PP G + + P K S +G G PGP GPQGP G PG Sbjct: 1143 PGPAGPVGPPGEDGDKGEIGEPGQKG---------SKGDKGEQGPPGPTGPQGPIGQPGP 1193 Query: 106 TGPKGEKGELGRPG---RKGRPGPPGVPGMPGPIGW---PGPEGPRGEKGDLGMMGLPGS 159 +G GE G G+ G +KG GP G PG PGP+G PGP G +GE GD+G MG PG Sbjct: 1194 SGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGP 1253 Query: 160 RGPMGSKGYPGSRGEKG---------SRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGE 210 GP G G PG+ G +G + GEKG+ G GE G PG G G KGE G KGE Sbjct: 1254 PGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGE 1313 Query: 211 PGIAGHRGPTGRPGKRGKQGQKGDSGVMG------PPGKPGPSGQPGRPGPPG------- 257 G +G GP G G G G KG G +G PPG+PGP+GQ G PG G Sbjct: 1314 SGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQ 1373 Query: 258 ---PPPAGQL-IMGPKGERGFPGPPG 279 P P G+ GP G+RG PGP G Sbjct: 1374 TGSPGPTGEPGPSGPPGKRGPPGPAG 1399 Score = 183 bits (465), Expect = 2e-46 Identities = 110/255 (43%), Positives = 130/255 (50%), Gaps = 37/255 (14%) Query: 86 GSLGSPGPPGPQGPPGLPGK---TGPKGEKGELGR---------PGRKGRPGPPGVPGMP 133 G++G G PG G PGLPG+ GPKGE+GE G PG KG PG G G P Sbjct: 1279 GAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSP 1338 Query: 134 GPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP 193 GP+G+PG GP GE G G G PG + G G PG G G GE G GP G++G P Sbjct: 1339 GPVGFPGDPGPPGEPGPAGQDGPPGDK---GDDGEPGQTGSPGPTGEPGPSGPPGKRGPP 1395 Query: 194 GFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRP 253 G G G++GE G KGE G+ G G TG G +G G+ G G+ G PG G G PG P Sbjct: 1396 GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSP 1455 Query: 254 GPPGPP--------PAGQLIMGPKGERGFP------GPPG-------RCLCGPTMNVNNP 292 GP GPP P + GPKGE+G P GPPG R L GP + P Sbjct: 1456 GPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP-QGSSGP 1514 Query: 293 SYGESVYGPSSPRVP 307 + + GPS P P Sbjct: 1515 KGEQGITGPSGPIGP 1529 Score = 182 bits (462), Expect = 5e-46 Identities = 102/216 (47%), Positives = 118/216 (54%), Gaps = 29/216 (13%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGR---------------PGRKGRPGPPGV 129 +G G PGPPGP G GLPG G KGE G++G+ PG G GP Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP--- 1271 Query: 130 PGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPK-- 187 PG IG PG G +GE G+ G GLPG GP G KG G +GE G G G GPK Sbjct: 1272 ---PGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGP 1328 Query: 188 -GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGP 246 G+ G G PG +G G+ GP GEPG AG GP PG +G G+ G +G GP G+PGP Sbjct: 1329 PGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGP---PGDKGDDGEPGQTGSPGPTGEPGP 1385 Query: 247 SGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPGR 280 SG PG+ GPPGP P Q G KGE G GPPG+ Sbjct: 1386 SGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGK 1421 Score = 180 bits (456), Expect = 3e-45 Identities = 94/191 (49%), Positives = 107/191 (56%), Gaps = 7/191 (3%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P G G GPPGP GP G G+ G KGE G G PG+ G GP G PG PGP G G Sbjct: 1383 PGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGI 1442 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD------LGPKGEKGFPGF 195 GP GE+G G G G GPMG G PG +G+ G +GEKG +GP GE+G G Sbjct: 1443 PGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGD 1502 Query: 196 PGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGP 255 G+ G +G GPKGE GI G GP G PG G G G G G G GP G+ G PGP Sbjct: 1503 RGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGP 1562 Query: 256 PGPP-PAGQLI 265 PGPP P G++I Sbjct: 1563 PGPPGPPGEVI 1573 Score = 179 bits (455), Expect = 3e-45 Identities = 99/221 (44%), Positives = 119/221 (53%), Gaps = 29/221 (13%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG------PIGW 138 +G +G PGP G GP G G+ GP G+ G LG PG KG+ G PG+PG PG IG+ Sbjct: 828 RGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGF 887 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 PG G GEKG G PG GP G +G G RGE+G RG G GPKG G G G Sbjct: 888 PGFPGANGEKGG---RGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGP 944 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRG------KQGQKGDSGVMGPPGKPG------- 245 G++G GP+G G G +GP G PGK G ++G+ G G GPPG PG Sbjct: 945 PGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGP 1004 Query: 246 -----PSGQPGRPGPPGPPPAGQL--IMGPKGERGFPGPPG 279 P G+ G PGPPGPP L + G +G +G PGP G Sbjct: 1005 TGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAG 1045 Score = 179 bits (454), Expect = 5e-45 Identities = 111/270 (41%), Positives = 126/270 (46%), Gaps = 44/270 (16%) Query: 54 PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKG 113 P F G + P P L QG G PGPPG GP G G+TGP GE+G Sbjct: 956 PTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERG 1015 Query: 114 ELGRPGRKGRPGPPGVPGM------PGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKG 167 G PG G G PG+ G PGP G PG +GP G +G G GLPG G +G KG Sbjct: 1016 HPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKG 1075 Query: 168 Y---PGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRP- 223 PG G GS GE+G G G G PG PG G G G KG PG G +GP GR Sbjct: 1076 NEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135 Query: 224 --------------------------GKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG 257 G+ G++G KGD G GPPG GP G G+PGP G Sbjct: 1136 LQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG 1195 Query: 258 ----PPPAGQLIM----GPKGERGFPGPPG 279 P P GQ + G +G RGFPGPPG Sbjct: 1196 ADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225 Score = 179 bits (453), Expect = 6e-45 Identities = 124/323 (38%), Positives = 138/323 (42%), Gaps = 72/323 (22%) Query: 47 PPPPLFPP--------PFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQG 98 PP P PP P +G P P P QG++G PG GP G Sbjct: 689 PPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLG 748 Query: 99 PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGE---------KG 149 PGLPG G G G G+ G G G G PG GPIG+PGP G +G KG Sbjct: 749 KPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKG 808 Query: 150 DLGMMGLPGSRGPMGSKGY------PGSRGEKGSRGEKG---------DLGPKGEKG--- 191 + G G PG +G MG KG PG RGE G G KG LGP GEKG Sbjct: 809 EKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLG 868 Query: 192 ------------------FPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKR------G 227 FPGFPG G+KG G G+PG G RGPTG G+R G Sbjct: 869 VPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITG 928 Query: 228 KQGQKGDSGVMGPPGKP------GPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRC 281 K G KG+SG GP G P GP G G PGP GPP GP G+ G PG PG+ Sbjct: 929 KPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPP-------GPPGKDGLPGHPGQR 981 Query: 282 LCGPTMNVNNPSYGESVYGPSSP 304 P V GP P Sbjct: 982 GETGFQGKTGPPGPPGVVGPQGP 1004 Score = 177 bits (450), Expect = 1e-44 Identities = 103/231 (44%), Positives = 119/231 (51%), Gaps = 39/231 (16%) Query: 86 GSLGSPGPPGPQGPPGLPG---KTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPE 142 G LG PG G G PGLPG + GPKG G G PG G G G PG PGP G GP Sbjct: 856 GPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPT 915 Query: 143 GPRGEKGDLGMMGLPGSR---------GPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP 193 GPRGE+G G+ G PG + GP G +G G +G G G KG GP G+ G P Sbjct: 916 GPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLP 975 Query: 194 GFPGMLGQ---KGEMGPKGEPGIAGHRGPTGR------------PGKRGKQGQKGDSGVM 238 G PG G+ +G+ GP G PG+ G +GPTG PG G+QG G +G Sbjct: 976 GHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKE 1035 Query: 239 GPPGKPGPSGQPGRPGPPG----------PPPAGQLIMGPKGERGFPGPPG 279 G G PGP+G PG+ GPPG P P G L G KG G PGPPG Sbjct: 1036 GTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGAL--GLKGNEGPPGPPG 1084 Score = 177 bits (450), Expect = 1e-44 Identities = 94/199 (47%), Positives = 113/199 (56%), Gaps = 12/199 (6%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGE---LGRPGRKGRPGPPGVPGMPGPIGWPGPE 142 G G GP GPQGP G PG GP G G+ G PG++G G G G PGP G GP+ Sbjct: 943 GPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQ 1002 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK 202 GP GE G +G G PG GP G +G PG G++G++G+ G G G+ G PG G G + Sbjct: 1003 GPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDR 1062 Query: 203 GEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-PA 261 G GP G G+ G+ GP G PG G G++ GP G GP G PGRPGP GPP PA Sbjct: 1063 GLPGPVGALGLKGNEGPPGPPGPAGSPGER------GPAGAAGPIGIPGRPGPQGPPGPA 1116 Query: 262 GQLIMGPKGERGFPGPPGR 280 G+ G GE+G GP GR Sbjct: 1117 GE--KGAPGEKGPQGPAGR 1133 Score = 170 bits (431), Expect = 2e-42 Identities = 103/246 (41%), Positives = 119/246 (48%), Gaps = 35/246 (14%) Query: 85 QGSLGSPGP---PGPQGPPGL---PGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG---- 134 +G+ G PGP PG GPPGL PG G G G LG G +G PGPPG G PG Sbjct: 1035 EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGP 1094 Query: 135 -----PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGE 189 PIG PG GP+G G G G PG +GP G G G +G G G G +GP GE Sbjct: 1095 AGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGE 1154 Query: 190 ---KGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQ---KGDSGVMGPPGK 243 KG G PG G KG+ G +G PG G +GP G+PG G G+ +G G+ G G Sbjct: 1155 DGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGD 1214 Query: 244 PGPSGQPGRPGPPG-----PPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESV 298 GP G PG PGP G PP + G G+ G PGPPG PS Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG---------PRGPSGAPGA 1265 Query: 299 YGPSSP 304 GP P Sbjct: 1266 DGPQGP 1271 Score = 169 bits (428), Expect = 5e-42 Identities = 100/233 (42%), Positives = 118/233 (50%), Gaps = 41/233 (17%) Query: 85 QGSLGSPGPPGPQGPPG------------LPGKTGPKGEKGE---LGRPGRKGRPGPPGV 129 QG G GPPGP G PG +PG+TGPKG++G G PG KG G PG Sbjct: 591 QGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGP 650 Query: 130 PGMPGPIGWPGPEGPRGEKGDLGMMGLPGS---------RGPMGSKGYPGSRGEKGSRGE 180 G PGP PG +G RG+ G++G GLPG +GP G G PG G G G Sbjct: 651 SGPPGP---PGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGP 707 Query: 181 KGDLGPKGE------------KGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGK 228 KG++GP+GE +G PG G +G GE GP G+PG+ G G G PG GK Sbjct: 708 KGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGK 767 Query: 229 QGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQL--IMGPKGERGFPGPPG 279 +G G+ G GPPG GP G PG G G L G KGE GFPG G Sbjct: 768 EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKG 820 Score = 167 bits (422), Expect = 2e-41 Identities = 108/290 (37%), Positives = 130/290 (44%), Gaps = 76/290 (26%) Query: 92 GPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVP---GMPGP------------- 135 GPPGP+GP GLPG G G G++G PG +G PG PG+P G+PGP Sbjct: 469 GPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGG 528 Query: 136 --------------------------------------IGWPGPEGP------RGEKGDL 151 G PGP GP +GE GD+ Sbjct: 529 GGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDV 588 Query: 152 GMMGLPGSRGPMGSKGYPGSRGEKGS---RGEKGDLGPKGEKGFPGFPGMLGQKGE---- 204 G G G +GP G G PG RG GS RG G GPKG++GF G G+ G+KG Sbjct: 589 GPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDP 648 Query: 205 --MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-PA 261 GP G PG G RG G G RG G+ G G++GP G PGP G PG G G P P Sbjct: 649 GPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPK 708 Query: 262 GQLIMGPKGERGFPG----PPGRCLCGPTMNVNNPSYGESVYGPSSPRVP 307 G +GP+GE G PG P + L GP + P + P P +P Sbjct: 709 GN--VGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMP 756 Score = 74.3 bits (181), Expect = 2e-13 Identities = 51/134 (38%), Positives = 63/134 (47%), Gaps = 19/134 (14%) Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKG 203 P ++G G+P ++ + +G G RGEKG +GE + P GML + Sbjct: 423 PTSSPSEIGP-GMPANQDTI-YEGIGGPRGEKGQKGEPAIIEP----------GMLIE-- 468 Query: 204 EMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQ 263 GP G G AG GP PG G GQ GD G GPPG+PG G G PGPPG Sbjct: 469 --GPPGPEGPAGLPGP---PGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLP 523 Query: 264 LIMGPKGERGFPGP 277 G G+ G GP Sbjct: 524 FRFGGGGDAGSKGP 537 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 200 bits (508), Expect = 2e-51 Identities = 105/216 (48%), Positives = 126/216 (58%), Gaps = 25/216 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP---E 142 G G PGP G +G G+PG GP+GEKG +G PG G PG PG+PG+PGP+G PG Sbjct: 351 GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP 410 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRG------EKGSRGEKGDLGPKGEKGFPGFP 196 GP+GE G +G G PG +G G +G+PG G G RG G +GPKGE G G P Sbjct: 411 GPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVP 470 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 G+ G G +GPKGEPGI G +G G P G G G SG +GPPG PGP G+PG PGPP Sbjct: 471 GLPGVPGLLGPKGEPGIPGDQGLQGPP---GIPGIGGPSGPIGPPGIPGPKGEPGLPGPP 527 Query: 257 G-------------PPPAGQLIMGPKGERGFPGPPG 279 G PP +GP+G+ G PGPPG Sbjct: 528 GFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPG 563 Score = 185 bits (469), Expect = 8e-47 Identities = 120/290 (41%), Positives = 148/290 (51%), Gaps = 65/290 (22%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDM-KNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 P P + PP G P+ P + K + Q P G G+PG PGPQGP G+PG Sbjct: 248 PGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPL--GKPGAPGEPGPQGPIGVPG 305 Query: 105 KTGPKGEKGELGRPGRKGRPGPPG---------VPGMPGPIG--------WPGPEG---- 143 GP G G +G+PG+ G PG PG +PG+PGP G +PGP+G Sbjct: 306 VQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGM 364 Query: 144 --------PRGEKGDLG------------MMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD 183 PRGEKG +G + G+PG GP G+ G+PG +GE G G +G Sbjct: 365 GGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGP 424 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 GPKGE G GFPG G GE+GP G G+ G GP +G+ GQKG G+ G PG Sbjct: 425 PGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGP------KGEAGQKGVPGLPGVPGL 478 Query: 244 PGPSGQPGRP------GPPGPP----PAGQL----IMGPKGERGFPGPPG 279 GP G+PG P GPPG P P+G + I GPKGE G PGPPG Sbjct: 479 LGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPG 528 Score = 182 bits (463), Expect = 4e-46 Identities = 118/283 (41%), Positives = 138/283 (48%), Gaps = 64/283 (22%) Query: 85 QGSLGSPGPPGPQGPPGLPGK--TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPE 142 QG G PGP GP GPPGLPG G KG+ G G PG G+PG PG+PG PG +G PG + Sbjct: 120 QGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPG-VGKPGMPGMPGKPGAMGMPGAK 178 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYP-----------------GSRGEKGSRGEKGDLG 185 G G+KG++G MG+PG +GP G G P G RG KG G +G G Sbjct: 179 GEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRG 238 Query: 186 PKGEKGF--PGFPGMLGQKGEMGPK--------GEPGIAGHRGP------TGRPGKRGKQ 229 PKG+KGF PG PG+ G G GP G+PG+ G GP G PG+ G Q Sbjct: 239 PKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQ 298 Query: 230 GQKGDSGVMGPPGKP--------------------GPSGQPGRPGPPGPPPAGQL-IMGP 268 G G GV GPPG P G G PG PGPPG P G+ GP Sbjct: 299 GPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGP 358 Query: 269 KGERGFPGPPG----RCLCGPTMNVNNPSYGESVYGPSSPRVP 307 KG+RG G PG R GP + P G P P +P Sbjct: 359 KGDRGMGGVPGALGPRGEKGP---IGAPGIGGPPGEPGLPGIP 398 Score = 167 bits (423), Expect = 2e-41 Identities = 95/201 (47%), Positives = 108/201 (53%), Gaps = 22/201 (10%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGR---PGRKGRPGPPGVPGMPGPIG----- 137 G G PG PGP GPPG G GPKGE G +G PG KG PG G PG PG +G Sbjct: 390 GEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPP 449 Query: 138 ----WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL---GPKGEK 190 PGP GP+GE G G+ GLPG G +G KG PG G++G +G G GP G Sbjct: 450 GMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPI 509 Query: 191 GFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 G PG PG G+ G GP G PGI G+PG G G G G +GP G+PG G P Sbjct: 510 GPPGIPGPKGEPGLPGPPGFPGI-------GKPGVAGLHGPPGKPGALGPQGQPGLPGPP 562 Query: 251 GRPGPPGPPPAGQLIMGPKGE 271 G PGPPGPP P+GE Sbjct: 563 GPPGPPGPPAVMPPTPPPQGE 583 Score = 165 bits (417), Expect = 9e-41 Identities = 106/231 (45%), Positives = 123/231 (53%), Gaps = 40/231 (17%) Query: 86 GSLGSPGPPGPQGPPGLPGKTG---PKGEKGELGRPGRKGRPGPPGVPGMPGPIG----- 137 G G PGP G +GP GLPG G PKG+KG G PG G GPPG+ G PGP+G Sbjct: 214 GLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPGVG 272 Query: 138 ------WPGPEGPRG------EKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLG 185 +PGP+GP G E G G +G+PG +GP G G G G+ G G+ G G Sbjct: 273 KPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPG 331 Query: 186 PKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGD---SGVMGPPG 242 KGE+G PG PG G G +G G PG G RG G PG G +G+KG G+ GPPG Sbjct: 332 GKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPG 390 Query: 243 KPGPSGQPGRPGPPG----PPPAG-------QLIMGPKGERG---FPGPPG 279 +PG G PG GPPG P P G Q GPKGE G FPG PG Sbjct: 391 EPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPG 441 Score = 155 bits (391), Expect = 9e-38 Identities = 106/276 (38%), Positives = 133/276 (48%), Gaps = 29/276 (10%) Query: 25 LALPSLDQKKRGGHKACCLLTPPPPPLFPP---------------PFFRGGRSPLLSPDM 69 ++L S+ + G + L P PP PP P + G + + +M Sbjct: 17 ISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLA--MGKEM 74 Query: 70 KNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGP----KGEKGELGRPGRKGRPG 125 +L E P + G + P GK P +GE+G G PG +G PG Sbjct: 75 PHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPK-KGKEIPLASLRGEQGPRGEPGPRGPPG 133 Query: 126 PPGVP--GMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD 183 PPG+P G+PG G PGP+G G G GM G+PG G MG G G G+KG G G Sbjct: 134 PPGLPGHGIPGIKGKPGPQGYPG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGI 192 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 GP+G G G PG +G+ G G G+PG G RGP G PG +G +G KGD G G PG Sbjct: 193 PGPQGPPGPHGLPG-IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGA 250 Query: 244 PGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 PG G PG GPPG P G +G G GFPGP G Sbjct: 251 PGVKGPPGMHGPPG--PVGLPGVGKPGVTGFPGPQG 284 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 200 bits (508), Expect = 2e-51 Identities = 105/216 (48%), Positives = 126/216 (58%), Gaps = 25/216 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP---E 142 G G PGP G +G G+PG GP+GEKG +G PG G PG PG+PG+PGP+G PG Sbjct: 351 GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP 410 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRG------EKGSRGEKGDLGPKGEKGFPGFP 196 GP+GE G +G G PG +G G +G+PG G G RG G +GPKGE G G P Sbjct: 411 GPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVP 470 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 G+ G G +GPKGEPGI G +G G P G G G SG +GPPG PGP G+PG PGPP Sbjct: 471 GLPGVPGLLGPKGEPGIPGDQGLQGPP---GIPGIGGPSGPIGPPGIPGPKGEPGLPGPP 527 Query: 257 G-------------PPPAGQLIMGPKGERGFPGPPG 279 G PP +GP+G+ G PGPPG Sbjct: 528 GFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPG 563 Score = 185 bits (469), Expect = 8e-47 Identities = 120/290 (41%), Positives = 148/290 (51%), Gaps = 65/290 (22%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDM-KNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 P P + PP G P+ P + K + Q P G G+PG PGPQGP G+PG Sbjct: 248 PGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPL--GKPGAPGEPGPQGPIGVPG 305 Query: 105 KTGPKGEKGELGRPGRKGRPGPPG---------VPGMPGPIG--------WPGPEG---- 143 GP G G +G+PG+ G PG PG +PG+PGP G +PGP+G Sbjct: 306 VQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGM 364 Query: 144 --------PRGEKGDLG------------MMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD 183 PRGEKG +G + G+PG GP G+ G+PG +GE G G +G Sbjct: 365 GGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGP 424 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 GPKGE G GFPG G GE+GP G G+ G GP +G+ GQKG G+ G PG Sbjct: 425 PGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGP------KGEAGQKGVPGLPGVPGL 478 Query: 244 PGPSGQPGRP------GPPGPP----PAGQL----IMGPKGERGFPGPPG 279 GP G+PG P GPPG P P+G + I GPKGE G PGPPG Sbjct: 479 LGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPG 528 Score = 182 bits (463), Expect = 4e-46 Identities = 118/283 (41%), Positives = 138/283 (48%), Gaps = 64/283 (22%) Query: 85 QGSLGSPGPPGPQGPPGLPGK--TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPE 142 QG G PGP GP GPPGLPG G KG+ G G PG G+PG PG+PG PG +G PG + Sbjct: 120 QGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPG-VGKPGMPGMPGKPGAMGMPGAK 178 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYP-----------------GSRGEKGSRGEKGDLG 185 G G+KG++G MG+PG +GP G G P G RG KG G +G G Sbjct: 179 GEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRG 238 Query: 186 PKGEKGF--PGFPGMLGQKGEMGPK--------GEPGIAGHRGP------TGRPGKRGKQ 229 PKG+KGF PG PG+ G G GP G+PG+ G GP G PG+ G Q Sbjct: 239 PKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQ 298 Query: 230 GQKGDSGVMGPPGKP--------------------GPSGQPGRPGPPGPPPAGQL-IMGP 268 G G GV GPPG P G G PG PGPPG P G+ GP Sbjct: 299 GPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGP 358 Query: 269 KGERGFPGPPG----RCLCGPTMNVNNPSYGESVYGPSSPRVP 307 KG+RG G PG R GP + P G P P +P Sbjct: 359 KGDRGMGGVPGALGPRGEKGP---IGAPGIGGPPGEPGLPGIP 398 Score = 167 bits (423), Expect = 2e-41 Identities = 95/201 (47%), Positives = 108/201 (53%), Gaps = 22/201 (10%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGR---PGRKGRPGPPGVPGMPGPIG----- 137 G G PG PGP GPPG G GPKGE G +G PG KG PG G PG PG +G Sbjct: 390 GEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPP 449 Query: 138 ----WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL---GPKGEK 190 PGP GP+GE G G+ GLPG G +G KG PG G++G +G G GP G Sbjct: 450 GMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPI 509 Query: 191 GFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 G PG PG G+ G GP G PGI G+PG G G G G +GP G+PG G P Sbjct: 510 GPPGIPGPKGEPGLPGPPGFPGI-------GKPGVAGLHGPPGKPGALGPQGQPGLPGPP 562 Query: 251 GRPGPPGPPPAGQLIMGPKGE 271 G PGPPGPP P+GE Sbjct: 563 GPPGPPGPPAVMPPTPPPQGE 583 Score = 165 bits (417), Expect = 9e-41 Identities = 106/231 (45%), Positives = 123/231 (53%), Gaps = 40/231 (17%) Query: 86 GSLGSPGPPGPQGPPGLPGKTG---PKGEKGELGRPGRKGRPGPPGVPGMPGPIG----- 137 G G PGP G +GP GLPG G PKG+KG G PG G GPPG+ G PGP+G Sbjct: 214 GLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPGVG 272 Query: 138 ------WPGPEGPRG------EKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLG 185 +PGP+GP G E G G +G+PG +GP G G G G+ G G+ G G Sbjct: 273 KPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPG 331 Query: 186 PKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGD---SGVMGPPG 242 KGE+G PG PG G G +G G PG G RG G PG G +G+KG G+ GPPG Sbjct: 332 GKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPG 390 Query: 243 KPGPSGQPGRPGPPG----PPPAG-------QLIMGPKGERG---FPGPPG 279 +PG G PG GPPG P P G Q GPKGE G FPG PG Sbjct: 391 EPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPG 441 Score = 155 bits (391), Expect = 9e-38 Identities = 106/276 (38%), Positives = 133/276 (48%), Gaps = 29/276 (10%) Query: 25 LALPSLDQKKRGGHKACCLLTPPPPPLFPP---------------PFFRGGRSPLLSPDM 69 ++L S+ + G + L P PP PP P + G + + +M Sbjct: 17 ISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLA--MGKEM 74 Query: 70 KNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGP----KGEKGELGRPGRKGRPG 125 +L E P + G + P GK P +GE+G G PG +G PG Sbjct: 75 PHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPK-KGKEIPLASLRGEQGPRGEPGPRGPPG 133 Query: 126 PPGVP--GMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD 183 PPG+P G+PG G PGP+G G G GM G+PG G MG G G G+KG G G Sbjct: 134 PPGLPGHGIPGIKGKPGPQGYPG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGI 192 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 GP+G G G PG +G+ G G G+PG G RGP G PG +G +G KGD G G PG Sbjct: 193 PGPQGPPGPHGLPG-IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGA 250 Query: 244 PGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 PG G PG GPPG P G +G G GFPGP G Sbjct: 251 PGVKGPPGMHGPPG--PVGLPGVGKPGVTGFPGPQG 284 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 199 bits (505), Expect = 6e-51 Identities = 109/249 (43%), Positives = 130/249 (52%), Gaps = 25/249 (10%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P GS G PGPPGP GP G G G GEKG+ G G+ G PGPPG PG PG +G PGP Sbjct: 1119 PGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGP 1178 Query: 142 EGPRGEKGDLGM---MGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 GP+ EKG G+ GLPGS GP G G G G G G+ G G +G+ G G PG+ Sbjct: 1179 PGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGL 1238 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGR---PGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGP 255 +G G G G PG+ G +G G+ PG G+ G +G+ G MGP G+PGP G G PGP Sbjct: 1239 MGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGP 1298 Query: 256 PGPP-PAGQLIMGPKGER------------------GFPGPPGRCLCGPTMNVNNPSYGE 296 PG P PAG +G KG+R G PGPPG P + Sbjct: 1299 PGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQ 1358 Query: 297 SVYGPSSPR 305 YGP P+ Sbjct: 1359 GFYGPPGPK 1367 Score = 189 bits (481), Expect = 3e-48 Identities = 112/244 (45%), Positives = 124/244 (50%), Gaps = 28/244 (11%) Query: 45 TPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 +P PP PP F G SP + L E + G G G PGP G PG PG Sbjct: 1043 SPGPPGPIGPPGFPGAVG---SPGLPGLQGERG------LTGLTGDKGEPGPPGQPGYPG 1093 Query: 105 KTGP------KGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPG 158 TGP KGE+G G G KG PGPPG G+PGP PGP GPRGE+G G G G Sbjct: 1094 ATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGP---PGPAGPRGERGPQGNSGEKG 1150 Query: 159 SRGPMGSKGYPGSRGEKGSRGEKGDLGPKG---EKGFPGFPGMLGQKGEMGPKGEPGIAG 215 +G G G+PG G G G+ G GP G EKG G G G G GP G PGI G Sbjct: 1151 DQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQG 1210 Query: 216 HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFP 275 G G GK GK G +GD G GPPG GP G G+ G PG P GPKG+ G P Sbjct: 1211 PAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLP-------GPKGDCGKP 1263 Query: 276 GPPG 279 GPPG Sbjct: 1264 GPPG 1267 Score = 184 bits (468), Expect = 1e-46 Identities = 100/211 (47%), Positives = 118/211 (55%), Gaps = 6/211 (2%) Query: 74 LELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGV---P 130 L LE ++ +G S G PG G PGLPG G G++GE G PG +G PGPPG P Sbjct: 995 LSLERPRAEEARGD-NSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPP 1053 Query: 131 GMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEK 190 G PG +G PG G +GE+G G+ G G GP G GYPG+ G G G KG+ G G Sbjct: 1054 GFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSA 1113 Query: 191 GFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 G G PG G +G GP G G G RGP G G++G QG +G G GPPG PG G+ Sbjct: 1114 GEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKV 1173 Query: 251 GRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 G PGPPGP + I GP G G PGPPG Sbjct: 1174 GSPGPPGPQAEKGSEGIRGPSGLPGSPGPPG 1204 Score = 176 bits (445), Expect = 5e-44 Identities = 97/209 (46%), Positives = 113/209 (54%), Gaps = 33/209 (15%) Query: 82 PCMQGSLGSPGPPGPQGP---PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 P +G G PG PGP+G PG PG TG G +GE G G +GRPGPPG G PGP G Sbjct: 1242 PGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQ 1301 Query: 139 PGP--------EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEK 190 PGP +G RG G+ G+ GLPG GP G+PG GE G+ G G GP G++ Sbjct: 1302 PGPAGISAVGLKGDRGATGERGLAGLPGQPGP---PGHPGPPGEPGTDGAAGKEGPPGKQ 1358 Query: 191 GFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 GF G PG PKG+PG AG +G G G+ G G G SG MGP G PGP+G+ Sbjct: 1359 GFYGPPG---------PKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGER 1409 Query: 251 GRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G PG P GP G G PG PG Sbjct: 1410 GHPGAP----------GPSGSPGLPGVPG 1428 Score = 163 bits (413), Expect = 3e-40 Identities = 115/321 (35%), Positives = 133/321 (41%), Gaps = 100/321 (31%) Query: 74 LELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTG-------------------------- 107 L + +S P QG G PGPPGP G PGL G G Sbjct: 895 LWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKS 954 Query: 108 -----------------PKGEKGELGRPG--------------------------RKGRP 124 KGEKG+ G PG +G P Sbjct: 955 ICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDP 1014 Query: 125 GPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYP---GSRGEKGSRGEK 181 G G PG+PGP PG G RGE+G GM G PG GP+G G+P GS G G +GE+ Sbjct: 1015 GCVGSPGLPGP---PGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGER 1071 Query: 182 GDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPP 241 G G G+KG PG PG G G GP G PGI G RG TG G++G+ G G G+ GPP Sbjct: 1072 GLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPP 1131 Query: 242 GKPGP------------------SGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLC 283 G GP GQPG PGPPGPP G G+ G PGPPG Sbjct: 1132 GPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPP-------GFPGKVGSPGPPGPQAE 1184 Query: 284 GPTMNVNNPSYGESVYGPSSP 304 + + PS GP P Sbjct: 1185 KGSEGIRGPSGLPGSPGPPGP 1205 Score = 155 bits (393), Expect = 5e-38 Identities = 116/336 (34%), Positives = 136/336 (40%), Gaps = 107/336 (31%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 P PP RG +SPD + C +G G G G GP GLPG Sbjct: 345 PGPPGSKGEKGARGNDCVRISPD----------APLQCAEGPKGEKGESGALGPSGLPGS 394 Query: 106 TGPKGEKGELG---------RPGRKGRPGP------------------------PGVPGM 132 TG KG+KGE G +PGR GRPG PG PG+ Sbjct: 395 TGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGL 454 Query: 133 PGP--IGWPG----PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP 186 PGP IG PG P GP G KGD G G+PG GP G G PG +GEKG E P Sbjct: 455 PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLP 514 Query: 187 KGEKGFPGFPGMLGQKGEMGP----KGEPGIAGHRGPTGRP------------------- 223 +G + F G PG G KGE G +G+PGI G +G G P Sbjct: 515 EGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGA 574 Query: 224 ---------------------GKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP--P 260 G +G++G G++G G PG PGP G G G G P P Sbjct: 575 SGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEP 634 Query: 261 AGQL------------IMGPKGERGFPGPPGRCLCG 284 L + GP GE+G PGPPG L G Sbjct: 635 CPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPG 670 Score = 155 bits (393), Expect = 5e-38 Identities = 110/327 (33%), Positives = 125/327 (38%), Gaps = 118/327 (36%) Query: 48 PPPLFPPPFFRG--GRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 PP L PP F+G G L P +G G PGPPG G PG G+ Sbjct: 1235 PPGLMGPPGFKGKTGHPGLPGP-----------------KGDCGKPGPPGSTGRPGAEGE 1277 Query: 106 TGPKGEKGELGRPGRKGRPGPPG--------------------------VPGMPGPIGWP 139 G G +G G PG G PGPPG +PG PGP G P Sbjct: 1278 PGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHP 1337 Query: 140 GPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGML 199 GP G G G G G PG +G G PG +G+ G+ G+KG G KG G PG P Sbjct: 1338 GPPGEPGTDGAAGKEGPPGKQGFYGP---PGPKGDPGAAGQKGQAGEKGRAGMPGGP--- 1391 Query: 200 GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMG-------------------- 239 G+ G MGP G PG AG RG G PG G G G G MG Sbjct: 1392 GKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMF 1451 Query: 240 -------------------PPGKPGPSGQ---PGRPGPPGPP------------------ 259 PG+PGP G+ PGRPG PG P Sbjct: 1452 DERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVR 1511 Query: 260 -------PAGQLIMGPKGERGFPGPPG 279 G + +G GE G PGPPG Sbjct: 1512 GLPGTKGEKGDIGIGIAGENGLPGPPG 1538 Score = 155 bits (392), Expect = 7e-38 Identities = 102/253 (40%), Positives = 120/253 (47%), Gaps = 46/253 (18%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G +GSPG G PGLPG+ G G KGE G G GP G PG PGP+G G +G + Sbjct: 576 GDVGSPG----FGLPGLPGRAGVPGLKGE---KGNFGEAGPAGSPGPPGPVGPAGIKGAK 628 Query: 146 GEK------------GDLGMMGLPGSRGPMGSKGYPGSR--GEKGSRGEKGDLGPKGEKG 191 GE GD+ ++ LPG G G G PG G++G GE+G G KG+ G Sbjct: 629 GEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAG 688 Query: 192 FPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGK---------------RGKQGQKGDSG 236 PG PG G G G GEPG+ G GP G G G+ GQ G G Sbjct: 689 NPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKG 748 Query: 237 VMGPPG--KPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSY 294 GP G +PG GQPG PG GPP G KG +G PGPPGR + GP P Sbjct: 749 EQGPEGVGRPGKPGQPGLPGVQGPP-------GLKGVQGEPGPPGRGVQGPQGEPGAPGL 801 Query: 295 GESVYGPSSPRVP 307 + G PR P Sbjct: 802 -PGIQGLPGPRGP 813 Score = 155 bits (391), Expect = 9e-38 Identities = 105/270 (38%), Positives = 131/270 (48%), Gaps = 21/270 (7%) Query: 23 GCLALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSP--DMKNLML-ELETS 79 G +P L +K +A +P PP P +G + P + NL ++ Sbjct: 590 GRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVV 649 Query: 80 QSPCMQGSLGSPGPPGPQGPPGLPGKTGP---KGEKGELGRPGRKGRPGPPGVPGMPGPI 136 P G G PGPPG G PG GK G KG+KG+ G PG G PG G PG+ G Sbjct: 650 ALPGPSGEKGEPGPPG-FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEP 708 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSK-GYPGSRGEKGSRGEKGDLGPKGEKGFPGF 195 G GP GP+GEKGD G P +G + G PG G KG +G +G +G G+ G PG Sbjct: 709 GVQGPAGPKGEKGD-GCTACPSLQGTVTDMAGRPGQPGPKGEQGPEG-VGRPGKPGQPGL 766 Query: 196 PGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGP 255 PG+ G G G +GEPG G RG G G+ G G G G+ GP G PGP+G+ G G Sbjct: 767 PGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS 825 Query: 256 PGPPPAGQLIMGPKGERGFPGPPGRCLCGP 285 PG KG G GPPG + GP Sbjct: 826 PGV----------KGATGPVGPPGASVSGP 845 Score = 152 bits (383), Expect = 8e-37 Identities = 110/314 (35%), Positives = 126/314 (40%), Gaps = 120/314 (38%) Query: 84 MQGSLGSPGPPGPQGP-----------PGLPGKTGPKGEKGELGRPGRKGR-----PGPP 127 M G G PGP G QGP PGLPG GP G KG G PG GR G P Sbjct: 737 MAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEP 796 Query: 128 GVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGS-----------RGEKG 176 G PG+PG G PGP GP G G+ G G PG +G G G PG+ +G+ G Sbjct: 797 GAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTG 856 Query: 177 SRGEKGDLGPKGEKGFPG-----------FPGMLGQKG-------EMGPKGEPGIAGHRG 218 RG G+ GP+GEKG PG F GM G G + GP+G PGI G G Sbjct: 857 LRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPG 916 Query: 219 PTGRPGKRG----------------------------------------------KQGQK 232 P G PG +G ++G+K Sbjct: 917 PPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEK 976 Query: 233 GDSGVMGPP--------------------------GKPGPSGQPGRPGPPG-PPPAGQLI 265 GD G+ G P G PG G PG PGPPG P G+ Sbjct: 977 GDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGE-- 1034 Query: 266 MGPKGERGFPGPPG 279 GP G RG PGPPG Sbjct: 1035 EGPPGMRGSPGPPG 1048 Score = 139 bits (351), Expect = 4e-33 Identities = 90/242 (37%), Positives = 108/242 (44%), Gaps = 47/242 (19%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTG------------------PKGEKGELGRPGRKGRPG 125 + G G PGPPG GPPG PG G PKG+ G G+ G+ G G Sbjct: 1324 LAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKG 1383 Query: 126 PPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE----- 180 G+PG PG G GP GP G G+ G G PG G G G PGS G+ + E Sbjct: 1384 RAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFI 1443 Query: 181 -------------------KGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTG 221 + + G PG PG G G G G PG+ G G G Sbjct: 1444 RQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREG 1503 Query: 222 R---PGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQL-IMGPKGERGFPGP 277 R PG RG G KG+ G +G G G +G PG PGP GPP G++ GP G++G PG Sbjct: 1504 RQGLPGVRGLPGTKGEKGDIG-IGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGI 1562 Query: 278 PG 279 PG Sbjct: 1563 PG 1564 Score = 139 bits (350), Expect = 5e-33 Identities = 94/244 (38%), Positives = 108/244 (44%), Gaps = 61/244 (25%) Query: 82 PCMQGS------LGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP 135 PC+ G+ L GP G +G GLPG G KGEKG G + P P Sbjct: 318 PCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCA---- 373 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD---------LGP 186 GP+G +GE G LG GLPGS G G KG G G KG G+ G +GP Sbjct: 374 ---EGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGP 430 Query: 187 KGEKGFPGFPGMLGQKGEMGP---------------------------KGEPGIAGHRGP 219 KG+KG PGF G G GE GP KG GI G GP Sbjct: 431 KGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGP 490 Query: 220 TGRPGKRGKQGQKGD------------SGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMG 267 G+PGK G +G+KGD +G PGKPGP G+PG P P P Q I G Sbjct: 491 GGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKG 550 Query: 268 PKGE 271 KGE Sbjct: 551 EKGE 554 Score = 121 bits (304), Expect = 1e-27 Identities = 84/250 (33%), Positives = 98/250 (39%), Gaps = 85/250 (34%) Query: 82 PCMQGSLGSPGPPGPQG---PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 P G+ G GPPG QG PPG G G G+KG+ G GR G PG PG G GP+G Sbjct: 1343 PGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGP 1402 Query: 139 PGPEGPRGE------KGDLGMMGLPGSRG------------------------------- 161 PGP G RG G G+ G+PGS G Sbjct: 1403 PGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRM 1462 Query: 162 --------------PMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMG- 206 P G G PG G GS G G +G +G +G PG G+ G KGE G Sbjct: 1463 QFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGD 1522 Query: 207 ----------------PKGEPGIA--GHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSG 248 P+G PG G GP G+ G+ G PG PGP G Sbjct: 1523 IGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQ------------QGIPGIPGPPGPMG 1570 Query: 249 QPGRPGPPGP 258 QPG+ G P Sbjct: 1571 QPGKAGHCNP 1580 Score = 64.3 bits (155), Expect = 2e-10 Identities = 33/78 (42%), Positives = 39/78 (50%), Gaps = 10/78 (12%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G PGPPGPQGPPG G++G G G+ G PG+PG PGP+G PG G Sbjct: 1529 GENGLPGPPGPQGPPGY----------GKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHC 1578 Query: 146 GEKGDLGMMGLPGSRGPM 163 G M + PM Sbjct: 1579 NPSDCFGAMPMEQQYPPM 1596 Score = 62.0 bits (149), Expect = 1e-09 Identities = 53/185 (28%), Positives = 70/185 (37%), Gaps = 52/185 (28%) Query: 170 GSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGK- 228 G +K RG K ++ P G + P G G G RG G PG +G+ Sbjct: 295 GRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEK 354 Query: 229 ----------------------QGQKGDSGVMGPPGKPGPSGQ---------------PG 251 +G+KG+SG +GP G PG +G+ PG Sbjct: 355 GARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPG 414 Query: 252 RPGPPGPP-------PAGQL----IMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYG 300 +PG G P P GQ +GP+G G PGPPG L GP + P G Sbjct: 415 KPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPG--LPGPP-GIGLPGTPGDPGG 471 Query: 301 PSSPR 305 P P+ Sbjct: 472 PPGPK 476 Score = 43.1 bits (100), Expect = 5e-04 Identities = 18/37 (48%), Positives = 23/37 (62%) Query: 80 QSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELG 116 Q P G +G+ GP G QG PG+PG GP G+ G+ G Sbjct: 1540 QGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAG 1576 >gi|119829187 alpha 1 type XVII collagen [Homo sapiens] Length = 1497 Score = 198 bits (503), Expect = 9e-51 Identities = 114/266 (42%), Positives = 139/266 (52%), Gaps = 42/266 (15%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGP------------PGVPGM 132 +G G+ G PGP GPPG+PG GPKG G PG +G PGP PGV G Sbjct: 643 KGERGAAGEPGPHGPPGVPGSVGPKGSSGS---PGPQGPPGPVGLQGLRGEVGLPGVKGD 699 Query: 133 PGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGF 192 GP+G PGP+G +GEKG G+ G PG RG G+ G PG++G G G G GP+GE+G Sbjct: 700 KGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGL 759 Query: 193 PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSG---------------V 237 G PG+ G G G G+PG+ G +GP G PG G+ G KG+ G V Sbjct: 760 TGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTV 819 Query: 238 MGPPGKPGPSGQPGRPGPPGPP-PAG-------QLIMGPKGERGFPGPPGRCLCGPTMNV 289 GPPG PG G PG PG PGP PAG + GP G G GPPG + GP Sbjct: 820 PGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPR 879 Query: 290 NNPSYGESVYGPSSPRVPVIFVVNNQ 315 P GE + GP P P F+ N++ Sbjct: 880 GPP--GEGLPGPPGP--PGSFLSNSE 901 Score = 182 bits (462), Expect = 5e-46 Identities = 111/265 (41%), Positives = 131/265 (49%), Gaps = 44/265 (16%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGM--------- 132 P M+G +G G GP GP G G G GEKGE G G G GPPGVPG Sbjct: 614 PGMEGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS 672 Query: 133 PGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGF 192 PGP G PGP G +G +G++G+ G+ G +GPMG G G +GEKG RG G+ G +G G Sbjct: 673 PGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGA 732 Query: 193 PGFPGMLGQKGEMGPKGE------------PGIAGHRGPTGRPGKRGKQGQKGDSGVMGP 240 G PG G G GP G PGI G GP+G PGK G G +G G+ G Sbjct: 733 VGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGT 792 Query: 241 PGKPGPSGQPGR---------------PGPPGPPPAGQLIMGPKGERGFPGPPGRC-LCG 284 PG+PG G+PG PGPPGPP A MGP G G PGP G L G Sbjct: 793 PGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGA----MGPPGPPGAPGPAGPAGLPG 848 Query: 285 --PTMNVNNPSYGESVYGPSSPRVP 307 +N+ P GP P +P Sbjct: 849 HQEVLNLQGPPGPPGPRGPPGPSIP 873 Score = 167 bits (422), Expect = 2e-41 Identities = 97/227 (42%), Positives = 120/227 (52%), Gaps = 34/227 (14%) Query: 107 GPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDL------GMMGLPGSR 160 G G KG++G PG KG G PG PG+PGP+G PGP+GP+G+KG + G MG G Sbjct: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 Query: 161 GPMGSKGY--PGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGE-------- 210 GPMG +G P GEKG RG G+ GP G G PG G G G GP+G Sbjct: 627 GPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQG 686 Query: 211 -------PGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK---PGPSGQPGRPGPPGPP- 259 PG+ G +GP G PG +G QG+KG G+ G PG PG G+PG G GP Sbjct: 687 LRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAG 746 Query: 260 PAGQLIMGPKGERGFPGPPG-RCLCGPTMNVNNPSYGESVYGPSSPR 305 P G GP+GE+G G PG R GP+ + P + GP P+ Sbjct: 747 PDGH--QGPRGEQGLTGMPGIRGPPGPSGDPGKP----GLTGPQGPQ 787 Score = 164 bits (414), Expect = 2e-40 Identities = 114/293 (38%), Positives = 137/293 (46%), Gaps = 71/293 (24%) Query: 85 QGSLGSPGPPGPQGPPGL---------PGKT---------GPKGEKGE------LGRPGR 120 +GS GSPGP GP GP GL PG GPKG++GE G PG Sbjct: 667 KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGM 726 Query: 121 KGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGS------RGE 174 +G PG G PG G +G GP+G +G +G+ G+ G+PG RGP G G PG +G Sbjct: 727 RGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGP 786 Query: 175 KGSRGEKGDLGPKGEKGFPG------------FPGMLGQKGEMGPKGEPGIAGHRGPTGR 222 +G G G G KGE G PG PG G G MGP G PG G GP G Sbjct: 787 QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGL 846 Query: 223 PGKR---GKQGQKGDSGVMGP-----PGKPGPSGQPGR--PGPPGP-------------- 258 PG + QG G G GP PG PGP G PG PGPPGP Sbjct: 847 PGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSG 906 Query: 259 PPAGQLIMGPKGERGFPGPPG----RCLCGPTMNVNNPSYGESVYGPSSPRVP 307 PP GPKG++G PGP G + L G + + + S+G ++ GP P P Sbjct: 907 PPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTS-GSSSFGLNLQGPPGPPGP 958 Score = 157 bits (398), Expect = 1e-38 Identities = 104/249 (41%), Positives = 116/249 (46%), Gaps = 54/249 (21%) Query: 85 QGSLGSPG---PPGPQGPPGLPGKTGPKGEKGELGRPGR---KGRPGPPG---------- 128 QG G PG PPGP G PG PG TGP+G +G G PGR KG PG PG Sbjct: 757 QGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSM 816 Query: 129 --VPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEK----- 181 VPG PGP G GP GP G G G GLPG + + +G PG G +G G Sbjct: 817 LTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPP 876 Query: 182 GDLGPKGE--KGFPGFPGMLGQKGEM---GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSG 236 G GP GE G PG PG E GP G PG G +G G PG RG QG++G G Sbjct: 877 GPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPG 936 Query: 237 ------------VMGPPGKPGPSGQPGRPGPPGPP-----PAG---------QLIMGPKG 270 + GPPG PGP G G G PG P P+G + GP G Sbjct: 937 FSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPG 996 Query: 271 ERGFPGPPG 279 G PGPPG Sbjct: 997 PPGPPGPPG 1005 Score = 145 bits (365), Expect = 9e-35 Identities = 100/251 (39%), Positives = 115/251 (45%), Gaps = 58/251 (23%) Query: 75 ELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRP---GRKGRPGPPGVPG 131 ++ TS+ M G PGPPG GPPG PG GP G G G +G PGPPG G Sbjct: 807 KIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRG 866 Query: 132 MPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGS---------KGYPGSRGEKGSRGEKG 182 PGP PGP GPRG G+ GLPG GP GS G PG G G +G++G Sbjct: 867 PPGP-SIPGPPGPRGPPGE----GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQG 921 Query: 183 DLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIA-GHRGPTGRPGKRGKQGQKGDSGVMGPP 241 GP+G +G G PG G +GP G PG +G +G KGD GV G Sbjct: 922 PPGPRGHQGEQGLPG-------FSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGAL 974 Query: 242 GKP-GP-----------SGQPGRPGPPGPP----PAGQLIM-----------------GP 268 G P GP SG PG PGPPGPP +GQ I G Sbjct: 975 GIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGV 1034 Query: 269 KGERGFPGPPG 279 +G G PGPPG Sbjct: 1035 QGPPGPPGPPG 1045 Score = 133 bits (334), Expect = 4e-31 Identities = 93/244 (38%), Positives = 111/244 (45%), Gaps = 41/244 (16%) Query: 43 LLTPPPPPLFP-------PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPG 95 +LT P PP P PP G P P + + L L+ G PGPPG Sbjct: 816 MLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEV-LNLQ-----------GPPGPPG 863 Query: 96 PQGPPG--LPGKTGPKGEKGELGRPGRKGRPG------------PPGVPGMPGPIGWPGP 141 P+GPPG +PG GP+G GE G PG G PG PPG PG PGP G GP Sbjct: 864 PRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGP 922 Query: 142 EGPRGEKGDLGMMGLPGSRGP---MGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 GPRG +G+ G+ G S + +G PG G +G +G+KGD G G G P P Sbjct: 923 PGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSE 982 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPG----KPGPSGQPGRPG 254 G M G PG G GP G G++ Q+ S M G G PG PG Sbjct: 983 GGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPG 1042 Query: 255 PPGP 258 PPGP Sbjct: 1043 PPGP 1046 Score = 90.5 bits (223), Expect = 3e-18 Identities = 92/316 (29%), Positives = 120/316 (37%), Gaps = 93/316 (29%) Query: 43 LLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGL 102 ++ PP PP PP G +S +++L L T+ + G G PGPPGP+GPPG+ Sbjct: 1176 IVGPPGPP--GPPGIPGNVWSSIS--VEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGV 1231 Query: 103 PGKTGP-KGEKGELGRPGRKGRPGPPGVPG-MPGPIGWPGPEGPRGE------------- 147 G E + R P V + GP G PGP+GP G+ Sbjct: 1232 SGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRG 1291 Query: 148 -----------KGDLGMMGLPGSRGPMGSKGYPGSRGE-KGSRGEKG-DLGPKGEKG--- 191 +G + G GS G G+ GE G RG G D+GP G G Sbjct: 1292 SSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAA 1351 Query: 192 ----FPGFPGML-----------------------------------GQKGEMGPKGEPG 212 + G G+L G G+ GP+G PG Sbjct: 1352 EGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPG 1411 Query: 213 I----AGHRGPTG--------RPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPP 260 I + + T +G GQKG+ G GP G GP+G PG PGPPGP Sbjct: 1412 ISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGP-- 1469 Query: 261 AGQLIMGPKGERGFPG 276 G KGE+G G Sbjct: 1470 -----RGHKGEKGDKG 1480 Score = 88.6 bits (218), Expect = 1e-17 Identities = 99/374 (26%), Positives = 119/374 (31%), Gaps = 162/374 (43%) Query: 89 GSPGPPGPQGPPGLPGKTGPKGEKGELGRPG------------RKGRPGPPGV------- 129 G PGPPGP GP G G GP+G +GE G PG +G PGPPG Sbjct: 906 GPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDK 965 Query: 130 --PGMPGPIGWP------------------GPEGPRGEKGDLGMMG-------------- 155 PG+PG +G P GP GP G G + G Sbjct: 966 GDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSD 1025 Query: 156 -----LPGSRGPMGSKGYPGS----RGEKGSRGEKGD----------------------- 183 L G +GP G G PG GE E Sbjct: 1026 SIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSE 1085 Query: 184 -------------------LGPKGEKGFPGFPG----MLGQKGEMGPK-----GEPGIA- 214 +GP+G G PG G + E+ + GI+ Sbjct: 1086 DILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISI 1145 Query: 215 GHRGPTGRPGKRGKQGQKGDS--------GVMGPPGKPGPSGQPGR-------------- 252 G GP G PG G ++ S G++GPPG PGP G PG Sbjct: 1146 GLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYL 1205 Query: 253 --------PGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMN-----------VNNPS 293 PGPPGPP GP G RG PG G N + +P Sbjct: 1206 HTAGLSFIPGPPGPP-------GPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPD 1258 Query: 294 YGESVYGPSSPRVP 307 + GP P P Sbjct: 1259 VRSFIVGPPGPPGP 1272 Score = 81.3 bits (199), Expect = 2e-15 Identities = 105/375 (28%), Positives = 121/375 (32%), Gaps = 148/375 (39%) Query: 43 LLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGL 102 L+ P PP PP G S LLS D EL + M S S G PGP GPPGL Sbjct: 1104 LMGPRGPP--GPPGASGDGS-LLSLDYA----ELSSRILSYMSSSGISIGLPGPPGPPGL 1156 Query: 103 PGKTGP------KGEKGELGRPGRKGRPGPPGVPG----------------------MPG 134 PG + +G + G G G PGPPG+PG +PG Sbjct: 1157 PGTSYEELLSLLRGSEFR-GIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPG 1215 Query: 135 PIGWPGPEGPRGEKGDLGMMG--------------------------LPGSRGPMGSKGY 168 P G PGP GPRG G G + + G GP G +G Sbjct: 1216 PPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGP 1275 Query: 169 PG-----SRGEKGSRGEKGDLGPKGEKGFPGFPGML----GQKGEMGPKGEPG-IAGHRG 218 PG S SRG + + + G G +G G G AG RG Sbjct: 1276 PGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRG 1335 Query: 219 PTGRP-GKRGKQGQKGDSG----------------------------------------- 236 P G G G G + G Sbjct: 1336 PYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAY 1395 Query: 237 -VMGPPGKPGPSGQPGRP------------------------GPPG-------PPPAGQL 264 V GPPG+PGP G PG GPPG P P G Sbjct: 1396 TVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGD- 1454 Query: 265 IMGPKGERGFPGPPG 279 GP G G PGPPG Sbjct: 1455 -RGPAGPPGHPGPPG 1468 Score = 77.4 bits (189), Expect = 2e-14 Identities = 48/116 (41%), Positives = 54/116 (46%), Gaps = 32/116 (27%) Query: 74 LELETSQSPCMQGSL--------GSPGPPGPQGPPGLP---------------------G 104 L + S+S QG L G PG PGPQGPPG+ Sbjct: 1376 LAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGA 1435 Query: 105 KTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSR 160 GP G+KGE+G PG KG GP G PG PGP PGP G +GEKGD G G R Sbjct: 1436 IQGPPGQKGEMGTPGPKGDRGPAGPPGHPGP---PGPRGHKGEKGDKGDQVYAGRR 1488 Score = 67.0 bits (162), Expect = 3e-11 Identities = 81/313 (25%), Positives = 104/313 (33%), Gaps = 91/313 (29%) Query: 23 GCLALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQS- 81 G L +PS GG + ++ PP P PP G +++ + E S S Sbjct: 972 GALGIPS--GPSEGGSSSTMYVSGPPGPPGPPG--PPGSISSSGQEIQQYISEYMQSDSI 1027 Query: 82 -PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGR----------------------- 117 + G G PGPPGP GP + TG + EL Sbjct: 1028 RSYLSGVQGPPGPPGPPGP--VTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSE 1085 Query: 118 -------------------PGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLP- 157 G +G PGPPG G + E + G+ Sbjct: 1086 DILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISI 1145 Query: 158 GSRGPMGSKGYPGSRGE------KGSRGEKGDLGPKGEKGFPGFPGML------------ 199 G GP G G PG+ E +GS +G +GP G G PG PG + Sbjct: 1146 GLPGPPGPPGLPGTSYEELLSLLRGSE-FRGIVGPPGPPGPPGIPGNVWSSISVEDLSSY 1204 Query: 200 ----GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGD-----------------SGVM 238 G GP G PG G RGP G G + S ++ Sbjct: 1205 LHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIV 1264 Query: 239 GPPGKPGPSGQPG 251 GPPG PGP G PG Sbjct: 1265 GPPGPPGPQGPPG 1277 Score = 67.0 bits (162), Expect = 3e-11 Identities = 39/92 (42%), Positives = 47/92 (51%), Gaps = 10/92 (10%) Query: 134 GPIGWPGPEGPRG--------EKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLG 185 GP G PGP+GP G +M + G + +G PG +GE G+ G KGD G Sbjct: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAI--QGPPGQKGEMGTPGPKGDRG 1456 Query: 186 PKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHR 217 P G G PG PG G KGE G KG+ AG R Sbjct: 1457 PAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRR 1488 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/90 (38%), Positives = 41/90 (45%), Gaps = 8/90 (8%) Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGV------MGPPGKPGPSGQPG 251 M +K M + + G GP G G G +G +G G +G PG GP GQ G Sbjct: 550 MFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKG 609 Query: 252 RPGPPG-PPPAGQL-IMGPKGERGFPGPPG 279 G PG P GQ GP G RG GPPG Sbjct: 610 SVGDPGMEGPMGQRGREGPMGPRGEAGPPG 639 Score = 42.7 bits (99), Expect = 7e-04 Identities = 20/43 (46%), Positives = 25/43 (58%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGR 123 +P +G G GPPG GPPG G G KG+KG+ GR+ R Sbjct: 1448 TPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRR 1490 Score = 37.7 bits (86), Expect = 0.021 Identities = 17/37 (45%), Positives = 22/37 (59%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRK 121 +G G PG PGP GP G G+ G KG++ GR R+ Sbjct: 1455 RGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRR 1491 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 195 bits (496), Expect = 6e-50 Identities = 112/255 (43%), Positives = 138/255 (54%), Gaps = 37/255 (14%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPI---GW 138 P + G GSPG PG +G PG G GP G KG G PGR G GPPG+PG+PGP G Sbjct: 839 PGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGL 898 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGE------------KGSRGEKGDLGP 186 PGP GP+G +G G G PG RG G++G PG++GE +G RG KG +GP Sbjct: 899 PGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGP 958 Query: 187 KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPP----G 242 G++G G GE GP G+ G G RG G P G QG++G+ G GPP G Sbjct: 959 PGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTP---GMQGRRGEPGRYGPPGFHRG 1015 Query: 243 KPGPSGQPGRPGPPGPPPAGQL--------IMGPKGERGFPGPPGRC----LCGPTMNVN 290 +PG GQPG PGPPGPP + L + G +GE G PGPPG GP N Sbjct: 1016 EPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKG 1075 Query: 291 NPSYGESVYGPSSPR 305 +P+ S +GP P+ Sbjct: 1076 DPA---SHFGPPGPK 1087 Score = 176 bits (446), Expect = 4e-44 Identities = 112/255 (43%), Positives = 129/255 (50%), Gaps = 45/255 (17%) Query: 91 PGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGV---PGMPGPIGWPGPEGPRGE 147 PGP GP GPPGLPG+ G KG+ G G G KG PGPPG PG+PG G GP G +G Sbjct: 496 PGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGA 555 Query: 148 KGDL------GMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGE-----KGFPGFP 196 KGD+ G G G GP G G PGS G G GEKGD GP G+ G GFP Sbjct: 556 KGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFP 615 Query: 197 GMLGQKGEMGPKGEPGIA--------GHRGPTGRPGKRGK---QGQKGDS--------GV 237 G LG G+ GP G PG+ GH G G PG RG +GQKGD+ G Sbjct: 616 GPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGR 675 Query: 238 MGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRC-LCGP---TMNVNNPS 293 GPPG GP G G PGP G P + G G +G PG PG + GP ++ +P Sbjct: 676 HGPPGFDGPPGPKGFPGPQGAPG----LSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPG 731 Query: 294 Y----GESVYGPSSP 304 + G S GP P Sbjct: 732 FGGEKGSSPVGPPGP 746 Score = 170 bits (430), Expect = 3e-42 Identities = 119/318 (37%), Positives = 135/318 (42%), Gaps = 77/318 (24%) Query: 28 PSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGS 87 P D RG +L PP PL PP P E P G Sbjct: 342 PKGDPGNRGHPGPPGVLVTPPLPLKGPPG---------DPGFPGRYGETGDVGPPGPPGL 392 Query: 88 LGSPG--------PPGPQGPPGLPGKTGPKGEKGEL-GRPGRKGRPGPPGVPGMP----- 133 LG PG PPGPQG PGLPG G G G PG+ G+PG PG+PG P Sbjct: 393 LGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGL 452 Query: 134 -------------------GPIGWPGPEGPRGEKGDLGMMGL-PGSRGPMGSKGYPGSRG 173 G +G PG GP+GEKG+ G+ PG GP G G PG +G Sbjct: 453 PGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQG 512 Query: 174 EKGS------RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPG------IAGHRGP-- 219 KG G KGD GP G +G PG PG G G G KG G + GH+G Sbjct: 513 SKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERG 572 Query: 220 -------TGRPGKRGKQGQKGDSGVMGPPGK-----------PGPSGQPGRPGPPGPPPA 261 G+PG G+ G G+ G GPPG PGP G PG+ GP GPP Sbjct: 573 PDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL 632 Query: 262 GQLIMGPKGERGFPGPPG 279 G GP GERG PG PG Sbjct: 633 G--FPGPPGERGHPGVPG 648 Score = 169 bits (429), Expect = 4e-42 Identities = 101/220 (45%), Positives = 118/220 (53%), Gaps = 24/220 (10%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVP---GMPGPIGW 138 P +G GSPG PG G G G G +G +G GRPG G GPPG P GMPG G Sbjct: 1084 PGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQ 1143 Query: 139 P---GPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKG-----DLGP---- 186 P G GPRG +GD G+ G PG +GP GS G G G KG +G KG D+GP Sbjct: 1144 PGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPV 1203 Query: 187 -----KGEKGFPGFPGML--GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMG 239 KGE+G PG PG+ G +G+ GP G PG +G GP G G+ K D G G Sbjct: 1204 GIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPK--DIPDPGPPG 1261 Query: 240 PPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G PGP G G PGPPG P + L+ G G+ G PGPPG Sbjct: 1262 DQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPG 1301 Score = 169 bits (429), Expect = 4e-42 Identities = 107/246 (43%), Positives = 123/246 (50%), Gaps = 46/246 (18%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGP---KGEKGELGRPGRKGR---PGPPGVPGMPGPIGW 138 +GS G PGPPG GPPG PG G +G+ GE+G PG +G PG PG PG+ GP G Sbjct: 1114 RGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGS 1173 Query: 139 PGPEGPRGEKGDLGMMGLPGSR--GPMGSKGYPGSRGEKGSRGEKG--DLGPKGEKGFPG 194 PG G G KG G G G GP G G PG +GE+G G G GP+G+KG PG Sbjct: 1174 PGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPG 1233 Query: 195 FPGMLGQKGEMGPKG-------EPGIAGHRGPTGRPGKRGK-------------QGQKGD 234 PG G G G G +PG G +GP G G RG +G+ GD Sbjct: 1234 PPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGD 1293 Query: 235 SGVMGPPGKPGPSGQPGRPGPPG-------------PPPAG-QLIMGPKGERGFPGPPGR 280 G+ GPPG PGP G PG G PG P P G GP GE+G PGPPGR Sbjct: 1294 CGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGR 1353 Query: 281 CLCGPT 286 GPT Sbjct: 1354 --KGPT 1357 Score = 169 bits (428), Expect = 5e-42 Identities = 107/248 (43%), Positives = 125/248 (50%), Gaps = 53/248 (21%) Query: 85 QGSLGSPGPPGPQGP------PGLPGKTGPKGEKGELGRPGR---KGRPGPPGVPGMPGP 135 +GS G PGPPGPQGP PG G +G KG +G+ G PG KG GP GVPG PG Sbjct: 61 KGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGL 120 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSR------------GPMGSKGYPGSRGEKGSR----- 178 G PG GP G +G GM G GSR GP G G+PG +GEKG+ Sbjct: 121 DGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILG 180 Query: 179 GEKGDLGPKGEKGFPGFPGMLGQKGEMGP---KGEPGIAGHRGPTGRPGKRGK-----QG 230 KG G +G+ G PG PG G G GP GEPG+ G G GRPG +G +G Sbjct: 181 AVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKG 240 Query: 231 QKGDSGVMGPPGKPGPS------------------GQPGRPGPPGPP-PAGQLIMGPKGE 271 Q GD G +G G PGP+ G PG G PGPP G+ +G KGE Sbjct: 241 QMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGE 300 Query: 272 RGFPGPPG 279 +G PG PG Sbjct: 301 KGIPGFPG 308 Score = 169 bits (427), Expect = 6e-42 Identities = 100/235 (42%), Positives = 117/235 (49%), Gaps = 18/235 (7%) Query: 54 PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKG 113 PP F G P P + +P + GS G G PG G +PG G +G+ G Sbjct: 678 PPGFDGPPGPKGFPGPQG---------APGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMG 728 Query: 114 ELGRPGRKGR-----PGPPGVPGMPGPIGWPGPE--GPRGEKGDLGMMGLPGSRGPMGSK 166 + G G KG PGPPG PG+ G G PG G G G G+ G+PG +GP G Sbjct: 729 DPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDP 788 Query: 167 GYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKR 226 G PG+ G G G G GPKG +G GFPG+ G G +G PGI G G G PG Sbjct: 789 GCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSP 848 Query: 227 GKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 G G KG G +GPPG G G PG PG PG PP I GP G+ G PGPPG Sbjct: 849 GAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPG 903 Score = 167 bits (424), Expect = 1e-41 Identities = 104/243 (42%), Positives = 117/243 (48%), Gaps = 42/243 (17%) Query: 46 PPPPPLFPPPFFRG--GRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLP 103 P PP PP G GR+P PD P G G PGP GP+G PG P Sbjct: 1232 PGPPGSSGPPGPAGATGRAPKDIPD-------------PGPPGDQGPPGPDGPRGAPGPP 1278 Query: 104 GKTGP----KGEKGELGRPGRKGRPGPPGVPG------------MPGPIGWPGPEGPRGE 147 G G +GE G+ G PG G PGPPG PG GP+G+PGP+GP G Sbjct: 1279 GLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGF 1338 Query: 148 KGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL----------GPKGEKGFPGFPG 197 G G GLPG G G G PG RGE G + D G +G +G G PG Sbjct: 1339 PGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPG 1398 Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG 257 M G G G KGEPG+ G RG G PG G G+KGD+G G PG PGP G G PGP G Sbjct: 1399 MRGPSGP-GCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKG 1457 Query: 258 PPP 260 P Sbjct: 1458 FGP 1460 Score = 163 bits (413), Expect = 3e-40 Identities = 107/257 (41%), Positives = 120/257 (46%), Gaps = 61/257 (23%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEG 143 M+G G PG PG GPPGLPG GP G+ G G PG KG G PG PG PG G PG EG Sbjct: 868 MKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEG 927 Query: 144 ---PRGEKGDLGMMGLPGSRG------------------------------PMGSKGYPG 170 +GE G+ GM GLPG RG P G G+PG Sbjct: 928 CPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPG 987 Query: 171 SRGEKGS------RGEKGDLGP----------KGEKGFPGFPGMLGQKGEMGPKGEPGIA 214 RG+KG+ RGE G GP KG+ G PG PG G G G G PG+ Sbjct: 988 ERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLP 1047 Query: 215 GHRGPTGRPGK---RGKQGQKGDSGVMGPP----GKPGPSGQPGRPGPPGPPPAG----- 262 G +G G PG G G +G G G P G PGP G+PG PG PG A Sbjct: 1048 GDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGL 1107 Query: 263 QLIMGPKGERGFPGPPG 279 I GP+G G PGPPG Sbjct: 1108 PGIQGPRGSPGRPGPPG 1124 Score = 163 bits (412), Expect = 3e-40 Identities = 105/263 (39%), Positives = 124/263 (47%), Gaps = 67/263 (25%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGK------TGPKGEKGEL------GRPGRKGRPGPPGV 129 P G+ G PGPPG +GPPGLPGK G KG KG++ G G +G GPPG Sbjct: 520 PGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGF 579 Query: 130 PGMPGP--------------------------IGWPGPEGPRGEKGDLGMMGL-----PG 158 PG PG G+PGP GP G+ G +G GL PG Sbjct: 580 PGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPG 639 Query: 159 SRGPMGSKGYPGSRGEKGSRGEKGD-----LGPKGEKGFPGFPGMLGQKGEMGPKGEPGI 213 RG G G+PG RG G +G+KGD + G G PGF G G KG GP+G PG+ Sbjct: 640 ERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGL 699 Query: 214 AGHRGPTGRPGKRGK---------QGQKGDSGV--------MGPPGKPGPSGQPGRPGPP 256 +G G GRPG G +G GD G +GPPG PG G G+ G P Sbjct: 700 SGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIP 759 Query: 257 GPPPAGQLIMGPKGERGFPGPPG 279 G P G L GP G+RG G PG Sbjct: 760 GDPAFGHL--GPPGKRGLSGVPG 780 Score = 161 bits (407), Expect = 1e-39 Identities = 101/247 (40%), Positives = 119/247 (48%), Gaps = 13/247 (5%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 P PP PP G P K ++ S+ +G G GPPG G PG G+ Sbjct: 529 PGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGR 588 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGS 165 G GEKG+ G PG PG G PGP+G PG GP G G LG G PG RG G Sbjct: 589 DGHAGEKGDPGPPGDH-EDATPGGKGFPGPLGPPGKAGPVGPPG-LGFPGPPGERGHPGV 646 Query: 166 KGYPGSRGEKGSRGEKGD-----LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPT 220 G+PG RG G +G+KGD + G G PGF G G KG GP+G PG++G G Sbjct: 647 PGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHK 706 Query: 221 GRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRP--GPPGPPPAGQLIMGPKGERGFPGPP 278 GRPG G G G G G PG G+ G GPPGPP + G G++G PG P Sbjct: 707 GRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSP----GVNGQKGIPGDP 762 Query: 279 GRCLCGP 285 GP Sbjct: 763 AFGHLGP 769 Score = 160 bits (405), Expect = 2e-39 Identities = 119/304 (39%), Positives = 134/304 (44%), Gaps = 58/304 (19%) Query: 55 PFFRGGRS------PLLSPDMKNLMLELETSQSPCMQGSL-GSPGPPGPQGPPGLPGKTG 107 P F GGR PL P K E S + G++ G G G G PGLPG G Sbjct: 148 PGFPGGRGALGPGGPLGHPGEKG-----EKGNSVFILGAVKGIQGDRGDPGLPGLPGSWG 202 Query: 108 PKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP--EGPRGEKGDLGMMGLPGS------ 159 G G G PG G GPPG PG PG G PG +G G+ G++G G PG Sbjct: 203 AGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEP 262 Query: 160 ------RGPMGSKGYPGSRGEKGSRGEKGD--LGPKGEKGFPGFPGMLGQKGEMGPKGEP 211 +G G KG PG G G G KG+ +G KGEKG PGFPG G G G G P Sbjct: 263 PDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFP 322 Query: 212 GIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKP-----------GPSGQPGRP------- 253 G+ G G G PG G G KGD G G PG P GP G PG P Sbjct: 323 GLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETG 382 Query: 254 --GPPGPP-------PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYG-PSS 303 GPPGPP A ++GP G +GFPG PG L G P G P S Sbjct: 383 DVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPG--LPGEAGIPGRPDSAPGKPGKPGS 440 Query: 304 PRVP 307 P +P Sbjct: 441 PGLP 444 Score = 159 bits (403), Expect = 4e-39 Identities = 102/225 (45%), Positives = 114/225 (50%), Gaps = 34/225 (15%) Query: 85 QGSLGSPG--PPGPQG---PPGLPGKTGPKGEKGELGR----------PGRKGRPGPPGV 129 +G GSPG PPGP+G PPG PG +GP G G GR PG +G PGP G Sbjct: 1212 RGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGP 1271 Query: 130 PGMPGPIGWPGP-EGPRGEKGDLGMMGLPGSRGPMGS---KGYPGSRGEKGSRGEKGDLG 185 G PGP G PG + RGE GD G+ G PG GP G KG+PG G+ G +G G G Sbjct: 1272 RGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPG 1331 Query: 186 PKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRP----------GKRGKQGQKGDS 235 P+G GFPG PG G G G KG G+ G RG G P G G G +G Sbjct: 1332 PQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPE 1391 Query: 236 GVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 G MG PG GPSG PG G PG G G G PGPPGR Sbjct: 1392 GAMGLPGMRGPSG-PGCKGEPGLDGR----RGVDGVPGSPGPPGR 1431 Score = 155 bits (393), Expect = 5e-38 Identities = 109/277 (39%), Positives = 129/277 (46%), Gaps = 70/277 (25%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGP--------------- 126 P G G PG PGP GP G PG +G G +G+ G PG +G GP Sbjct: 115 PGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGN 174 Query: 127 -----------------PGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYP 169 PG+PG+PG G GP GP G G+ G++G PG G G KG P Sbjct: 175 SVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNP 234 Query: 170 -----GSRGEKGSRGEKGDLGP------------KGEKGFPGFPGML------GQKGE-- 204 G G+ G G++G GP KGEKG G PGM+ G+KGE Sbjct: 235 GVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG 294 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGK---QGQKGDSGVMGPP---GKPGPSGQPGRPGPPGP 258 +G KGE GI G GP G PG G G KG+ G++G P G GP G PG G PGP Sbjct: 295 IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGP 354 Query: 259 PPAGQLIMGP---KGERGFPGPPGRCLCGPTMNVNNP 292 P G L+ P KG G PG PGR G T +V P Sbjct: 355 P--GVLVTPPLPLKGPPGDPGFPGR--YGETGDVGPP 387 Score = 152 bits (385), Expect = 5e-37 Identities = 125/365 (34%), Positives = 143/365 (39%), Gaps = 90/365 (24%) Query: 22 AGCLALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGG-------RSPLLSPDMKNLML 74 AG LP L + G H PP P P PF G + P P Sbjct: 866 AGMKGLPGLPGRP-GAHG------PPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPG 918 Query: 75 ELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKG--------------------- 113 E P +G G+ G PG +G GLPG G +G KG Sbjct: 919 E---RGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPG 975 Query: 114 ELGRP------------------GRKGRP----------GPPGVPGMPGPIGWPGPEGPR 145 E G P GR+G P G PG G PGP G PGP G Sbjct: 976 EPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGST 1035 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL----------GPKGEKGFPGF 195 G +G +G GLPG +G GS G PG G G+RG KG+ GPKGE G PG Sbjct: 1036 GLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGC 1095 Query: 196 PGMLGQKGEM---------GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGP 246 PG G GE G G PG G GP G PG G G +G G MG PG G Sbjct: 1096 PGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGL 1155 Query: 247 SGQPGRPGPPG-PPPAGQL----IMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGP 301 G PG PGPPG P+G + G KG++G G G GP V P P Sbjct: 1156 QGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDP 1215 Query: 302 SSPRV 306 SP + Sbjct: 1216 GSPGI 1220 Score = 149 bits (377), Expect = 4e-36 Identities = 106/286 (37%), Positives = 123/286 (43%), Gaps = 56/286 (19%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 P PP PP G P ++ E+ +QG G PGPPG +GP G PG Sbjct: 1120 PGPPGSSGPPGCPGDHG---MPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGL 1176 Query: 106 TGPKGEKGELGRPGRKGR-----PGPPGVPGMPGPIGWPG-----PEGPRGEKG------ 149 G G KG+ G G G PGP G+PG+ G G PG P GPRG+KG Sbjct: 1177 NGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPG 1236 Query: 150 -------------------------DLGMMGLPGSRGPMGSKGYPGS----RGEKGSRGE 180 D G G G RG G G PGS RGE G G Sbjct: 1237 SSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGL 1296 Query: 181 KGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGP 240 G GP G G PG+ G G G+ G KG G G +GP G PG G++G G G GP Sbjct: 1297 PGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGP 1356 Query: 241 PGKPGPSGQPGRPGP-------PGPPPAGQLIMGPKGERGFPGPPG 279 G PGP G+PG P PG P A + GP+G G PG G Sbjct: 1357 TGLPGPRGEPGPPADVDDCPRIPGLPGAPGM-RGPEGAMGLPGMRG 1401 Score = 147 bits (371), Expect = 2e-35 Identities = 109/305 (35%), Positives = 130/305 (42%), Gaps = 91/305 (29%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGE-----KGELGRPGRKGRPGPPG------------ 128 G G PG PG GPPG PG+ G KG KG++G PG G+ G PG Sbjct: 208 GPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCL 267 Query: 129 ------VPGMPGPIGWPGPEGPRGE-----KGDLGMMGLPGSRGPMGSKGYPGSRGEKGS 177 + G+PG +G PGP G +GE KG+ G+ G PG RG GS G PG G KG Sbjct: 268 YKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGE 327 Query: 178 RGEKGD------LGPKGEKGF-----------------------PGFPGMLGQKGEMGPK 208 G GD +GPKG+ G PGFPG G+ G++GP Sbjct: 328 LGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPP 387 Query: 209 GEPGIAGHRGPTGRPGKR--GKQGQKGDSGVMGPPGKPGPSGQPGR----PGPPGPP--- 259 G PG+ G RPG+ G G G G G PG PG +G PGR PG PG P Sbjct: 388 GPPGLLG------RPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSP 441 Query: 260 -----------PAGQLIM------GPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPS 302 P +I GP+G +G GPPG GP N GP Sbjct: 442 GLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGG--RGPKGEKGNEGLCACEPGPM 499 Query: 303 SPRVP 307 P P Sbjct: 500 GPPGP 504 Score = 131 bits (330), Expect = 1e-30 Identities = 73/173 (42%), Positives = 87/173 (50%), Gaps = 23/173 (13%) Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 G GP GP G +G +G +G PG G G KG G RG G+ G+KGD GP G GFPG Sbjct: 62 GSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLD 121 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPS--------- 247 G+ G G GP+G+PG++GH G G PG G +G G G +G PG+ G Sbjct: 122 GIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGA 181 Query: 248 --------GQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNP 292 G PG PG PG AG GP G G+PG PG L GP P Sbjct: 182 VKGIQGDRGDPGLPGLPGSWGAG----GPAGPTGYPGEPG--LVGPPGQPGRP 228 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 194 bits (492), Expect = 2e-49 Identities = 112/257 (43%), Positives = 126/257 (49%), Gaps = 37/257 (14%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPG---PPGVPG------- 131 P GS G GPPGP G G PG G G KG+ G+PG KG PG PPG PG Sbjct: 893 PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGI 952 Query: 132 -----------MPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE 180 MPGP G PGP+G +GE G G GL G RGP G +G PG G G G Sbjct: 953 TGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGR 1012 Query: 181 KGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGP 240 G+ G G G G PG G +GE G G PG GH GP G G GK G +G+SG GP Sbjct: 1013 DGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGP 1072 Query: 241 PGKPGPSGQPGRPGPPGP-----PPAGQLIMGPKGERGFPGPPGR----CLCGPTMNVNN 291 G PGP+G G PGP GP + G KG RGFPG PG G + + Sbjct: 1073 AGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGS 1132 Query: 292 PSYGESVYGPSSPRVPV 308 P GP+ PR PV Sbjct: 1133 P-------GPAGPRGPV 1142 Score = 189 bits (479), Expect = 6e-48 Identities = 113/267 (42%), Positives = 129/267 (48%), Gaps = 53/267 (19%) Query: 48 PPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTG 107 PP L P RGG P P +G G+ GPPGP G G PG G Sbjct: 685 PPGLAGAPGLRGGAGP------------------PGPEGGKGAAGPPGPPGAAGTPGLQG 726 Query: 108 PKGEKGELGRP---GRKGRPGPPGVPGMP---------GPIGWPGPEGPRGEKGDLGMMG 155 GE+G LG P G KG PG PG G+P GPIG PGP G G+KG+ G G Sbjct: 727 MPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG 786 Query: 156 LPGSRGPMGS------------KGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKG 203 LPG GP GS G+PG+ G+ G G KG+ G GEKG G PG+ G G Sbjct: 787 LPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPG 846 Query: 204 EMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK------PGPSGQPGRPGPPG 257 GP G PG G +G G PG G G G G+ GPPG PGPSG PG+ GPPG Sbjct: 847 GSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPG 906 Query: 258 P-----PPAGQLIMGPKGERGFPGPPG 279 P P + GPKG+ G PG G Sbjct: 907 PAGNTGAPGSPGVSGPKGDAGQPGEKG 933 Score = 188 bits (477), Expect = 1e-47 Identities = 104/206 (50%), Positives = 114/206 (55%), Gaps = 16/206 (7%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMP---GPIGWPGPE 142 G G GPPGP G PG PG+ G G KGE G PG KG GPPGV G P GP G PGP+ Sbjct: 798 GERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQ 857 Query: 143 GPRGEKGD---LGMMGLPGSR---GPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 G +GE+G G G PG+R GP GS G PG G GS G+ G GP G G PG P Sbjct: 858 GVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSP 917 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR---P 253 G+ G KG+ G GE G G +GP G PG G G G G+ GPPG PGP G PG Sbjct: 918 GVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK 977 Query: 254 GPPGPPPAGQLIMGPKGERGFPGPPG 279 G G P A G GERG PGP G Sbjct: 978 GESGKPGAN----GLSGERGPPGPQG 999 Score = 185 bits (470), Expect = 6e-47 Identities = 114/244 (46%), Positives = 123/244 (50%), Gaps = 44/244 (18%) Query: 82 PCMQGSLGSPGPPGPQGP---PGLPGKTGPKG------EKGELGRPGRKGRPGPPGVPGM 132 P QG G PGPPGP GP PG+ G GPKG + GE G PG G GPPG G Sbjct: 554 PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613 Query: 133 PGPIGWPGPEGPRGEKGDL------GMMGLPGSRGPMGSKGYPGSRGEKGSRGE------ 180 GP G PGP GP G+KGD G+ GLPG+ GP G G PG G KG G Sbjct: 614 TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG 673 Query: 181 KGDLGPKGEKGFPGF------------PGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGK 228 KGD G GE+G PG PG G KG GP G PG AG G G PG+RG Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733 Query: 229 QGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-------PAGQLIMGPKGERGFPGPPGRC 281 G G G G PG PG G PG+ GP GP PAGQ G KGE G PG PG Sbjct: 734 LGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQ--PGDKGEGGAPGLPG-- 789 Query: 282 LCGP 285 + GP Sbjct: 790 IAGP 793 Score = 185 bits (470), Expect = 6e-47 Identities = 106/234 (45%), Positives = 118/234 (50%), Gaps = 17/234 (7%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G GPPGPQG GLPG GP GE G+ G PG KG G PG PG G G PG GP Sbjct: 627 GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPP 686 Query: 146 GEKGDLGMMGLPGSRGPMGSKGY------------PGSRGEKGSRGEKGDLGPKGEKGFP 193 G G G+ G G GP G KG PG +G G RG G GPKG+KG P Sbjct: 687 GLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEP 746 Query: 194 GFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRP 253 G PG G G+ GP+G G G GP G+PG +G+ G G G+ GP G PG G+ G P Sbjct: 747 GGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPP 806 Query: 254 GPPGPP--PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 GP G P P G KGERG PG G G V P G GP P+ Sbjct: 807 GPAGFPGAPGQNGEPGGKGERGAPGEKGE---GGPPGVAGPPGGSGPAGPPGPQ 857 Score = 184 bits (466), Expect = 2e-46 Identities = 106/250 (42%), Positives = 123/250 (49%), Gaps = 14/250 (5%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P + G+ G PG G G GLPG+ G G KG+ G G G PG PG PG PGP+G G Sbjct: 1001 PGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGK 1060 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGF---PGFPGM 198 G RGE G G G PG G G+ G G RG+KG GE+G G KG +GF PG PG Sbjct: 1061 SGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGS 1120 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 G G+ G G PG AG RGP G G GK G G G +GPPG G G+ G G PG Sbjct: 1121 PGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGH 1180 Query: 259 PPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRV---PVIFVVNNQ 315 P G G G PG PG C CG G G +P P+ F +N Sbjct: 1181 P-------GQPGPPGPPGAPGPC-CGGVGAAAIAGIGGEKAGGFAPYYGDEPMDFKINTD 1232 Query: 316 EELERLNTQN 325 E + L + N Sbjct: 1233 EIMTSLKSVN 1242 Score = 180 bits (457), Expect = 2e-45 Identities = 101/222 (45%), Positives = 113/222 (50%), Gaps = 23/222 (10%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPK------GEKGELGRPGRKGRPGPP------G 128 SP QG G PG GP GPPG PG GP GE G GRPG +G PGPP G Sbjct: 196 SPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAG 255 Query: 129 VPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKG 188 +PG PG G G +G GEKG+ G GL G G G G PG G +G+ GE+G G G Sbjct: 256 IPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPG 315 Query: 189 EKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSG 248 G G G G G+ GP G PG AG G G G+ G G G +G G G+PGP G Sbjct: 316 AAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQG 375 Query: 249 QPGRPGPPGPP-----PAGQLIMGPKGERGFP------GPPG 279 G GPPGPP P G+ MGP G G P GPPG Sbjct: 376 HAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPG 417 Score = 180 bits (456), Expect = 3e-45 Identities = 100/229 (43%), Positives = 116/229 (50%), Gaps = 8/229 (3%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P G G PGPPG G PG PG G +G GE G+ G G PGPPG G GP G G Sbjct: 173 PGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGE 232 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEK---GSRGEKGDLGPKGEKGFPGFPGM 198 G G G+ G+ G PG +GP G G+PG +G + G GEKG+ G G KG G PG Sbjct: 233 SGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGE 292 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 G G MGP+G PG G G G G RG G +G G GPPG PG +G PG PG G Sbjct: 293 NGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGE 352 Query: 259 --PPAGQLIMGPKGERGFPGPPGRC-LCGP--TMNVNNPSYGESVYGPS 302 P G G+RG PGP G GP +N G+ GP+ Sbjct: 353 VGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA 401 Score = 179 bits (454), Expect = 5e-45 Identities = 113/271 (41%), Positives = 129/271 (47%), Gaps = 30/271 (11%) Query: 48 PPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPC---MQGSLGSPGPPG------PQG 98 PP + PP GG P P + + E + P G+ G PGPPG P G Sbjct: 838 PPGVAGPP---GGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG 894 Query: 99 PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPG 158 P G PGK GP G G G PG G GP G G PG G PG +GP G G LG+ G+ G Sbjct: 895 PSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITG 954 Query: 159 SRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGF---PGMLGQKGEMGPKGEPGIAG 215 +RG G G PG RG G +G KG+ G G G G PG G G G GEPG G Sbjct: 955 ARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG 1014 Query: 216 HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP-PPAGQLIMGPKGERGF 274 + G G PG+ G G KGD G G PG PG PG PGPPGP PAG+ G +GE G Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGENGSPGAPGA---PGHPGPPGPVGPAGK--SGDRGESGP 1069 Query: 275 PGPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 GP G P+ GP PR Sbjct: 1070 AGPAG---------APGPAGSRGAPGPQGPR 1091 Score = 178 bits (452), Expect = 8e-45 Identities = 108/252 (42%), Positives = 124/252 (49%), Gaps = 36/252 (14%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPG------------------P 126 +GS G PGPPGP G G PG G KGE G G PG G PG P Sbjct: 326 RGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGP 385 Query: 127 PGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP 186 PG+ G PG G GP G G G +G G PG G G+ G G GE G G KG+ GP Sbjct: 386 PGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGP 445 Query: 187 KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGP 246 +GE+G G PG+ G KGE G G PG G G G G+RG G +G +G G PG+ GP Sbjct: 446 RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGP 505 Query: 247 SGQPGRPGPPGP-----PPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNP----SYGES 297 +G+ G PGP GP P + G G RG PG PG GP + P S GES Sbjct: 506 AGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPG----GPGSD-GKPGPPGSQGES 560 Query: 298 ----VYGPSSPR 305 GPS PR Sbjct: 561 GRPGPPGPSGPR 572 Score = 178 bits (451), Expect = 1e-44 Identities = 99/214 (46%), Positives = 116/214 (54%), Gaps = 19/214 (8%) Query: 81 SPCMQGSLGSPGPPGPQGP---PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIG 137 SP GS G PGPPG QG PG PG +GP+G+ G +G PG KG G PG G G G Sbjct: 541 SPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPG 600 Query: 138 WPGPEGPRGEKGDLGMMGLPGSRGPMGSK------------GYPGSRGEKGSRGEKGDLG 185 PGP+GP G+ G+ G G PG GP G K G PG+ G G G+ G+ G Sbjct: 601 GPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPG 660 Query: 186 PKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPG 245 PKG+ G PG PG G G G +G PG+AG G G G G +G K G GPPG PG Sbjct: 661 PKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK---GAAGPPGPPG 717 Query: 246 PSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 +G PG G PG G GPKG++G PG PG Sbjct: 718 AAGTPGLQGMPG-ERGGLGSPGPKGDKGEPGGPG 750 Score = 174 bits (441), Expect = 1e-43 Identities = 101/237 (42%), Positives = 117/237 (49%), Gaps = 14/237 (5%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGE---------LGRPGRKGRPGPPGVPGM 132 P G G+PG GP GP G+PG+ GP GE+G G PGR G PG PG+ GM Sbjct: 479 PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGM 538 Query: 133 PGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGF 192 PG G PG +G G G G G PG GP G +G PG G G +G G G GE+G Sbjct: 539 PGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGG 598 Query: 193 PGFPGML---GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQ 249 PG PG G+ GE GP+G PG G G G G G QG +G G GPPG+ G G+ Sbjct: 599 PGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGE 658 Query: 250 PGRPGPPGPP--PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 PG G G P P G+ G GERG PG G P G+ GP P Sbjct: 659 PGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP 715 Score = 174 bits (441), Expect = 1e-43 Identities = 116/295 (39%), Positives = 131/295 (44%), Gaps = 55/295 (18%) Query: 47 PPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKT 106 PP P P G + P + L T P G G PGP G G PG PG Sbjct: 619 PPGPTGPG----GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGK 674 Query: 107 GPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW---PGPEGPRGEKGDLGMMGLPGSRGPM 163 G G GE G PG G PG G G PGP G GP GP G G G+ G+PG RG + Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGL 734 Query: 164 GSKGYPGSRGEKGS------------RGEKGDLGP---------KGEKGFPGFPGML--- 199 GS G G +GE G RG G +GP KGE G PG PG+ Sbjct: 735 GSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPR 794 Query: 200 ---GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 G++GE GP G G G G G PG +G++G G+ G GPPG GP G G GPP Sbjct: 795 GSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP 854 Query: 257 GPPPAGQLIMGPKGERGFPGPPG-------RCLCGPTMNVNNPSYGESVYGPSSP 304 GP G KGERG PG PG R L GP + NP GP P Sbjct: 855 GP-------QGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNP-------GPPGP 895 Score = 173 bits (438), Expect = 3e-43 Identities = 97/226 (42%), Positives = 117/226 (51%), Gaps = 10/226 (4%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGV---PGMPGPIGWPGPE 142 G +G G PG +G PGLPG G +G G G G+ G PGPPG PG PG G GP Sbjct: 297 GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK 202 G G G G G PG +G G++G PG G GS G KG++GP G PG PG++G + Sbjct: 357 GSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGP---AGIPGAPGLMGAR 413 Query: 203 GEMGPKGEPGIAGHRGPTGRPGKRGKQGQ---KGDSGVMGPPGKPGPSGQPGRPGPPGPP 259 G GP G G G RG G PGK G +G+ +G+ G G PG PG G+ G+ G PG P Sbjct: 414 GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473 Query: 260 PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 A L G GERG PG G P+ GP+ PR Sbjct: 474 GANGL-PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPR 518 Score = 172 bits (435), Expect = 7e-43 Identities = 105/248 (42%), Positives = 116/248 (46%), Gaps = 36/248 (14%) Query: 66 SPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGL------PGKTGPKGEKGELGRPG 119 SP K M +P + G+ G PGP G G PGL PGK G KGE G G G Sbjct: 391 SPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERG 450 Query: 120 RKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRG 179 G PG PG G G G PG G G G G G PG RGP G G PG +G G RG Sbjct: 451 EAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERG 510 Query: 180 EKGDLGPK------GEKGFPGFPGMLGQKGE---MGPKGEPGIAGHRGPTGRPGKRGKQG 230 G GP+ G G PG PGM G G G G+PG G +G +GRPG G G Sbjct: 511 APGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSG 570 Query: 231 QKGDSGVM---------GPPGKPGPSGQPGRPGPPGPP----------PAGQLIMGPKGE 271 +G GVM G PGK G G PG PGP GPP P G GP G+ Sbjct: 571 PRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGP--TGPGGD 628 Query: 272 RGFPGPPG 279 +G GPPG Sbjct: 629 KGDTGPPG 636 Score = 172 bits (435), Expect = 7e-43 Identities = 101/227 (44%), Positives = 116/227 (51%), Gaps = 29/227 (12%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKG------------------ELGRPGRKGR 123 P G+ G PGP G +G G+PG G KGE G E G PG +G Sbjct: 434 PGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGP 493 Query: 124 PGPPGVPGMPGPIGW---PGPEGPRGEKGDLGMMGLPGS---RGPMGSKGYPGSRGEKG- 176 GP G+PG GP G PGP GPRG G+ G G+PG RG GS G PGS G+ G Sbjct: 494 AGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP 553 Query: 177 --SRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGD 234 S+GE G GP G G G PG++G G G G PG G RG G PG +G G+ G+ Sbjct: 554 PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613 Query: 235 SGVMGPPGKPGPSGQPGRPGPPGPPPAGQL--IMGPKGERGFPGPPG 279 +G GPPG GP G G GPPGP L GP GE G PG PG Sbjct: 614 TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPG 660 Score = 169 bits (428), Expect = 5e-42 Identities = 94/198 (47%), Positives = 103/198 (52%), Gaps = 9/198 (4%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G PG G G PGLPG GP+G GE G G PGP G PG PG G PG +G R Sbjct: 771 GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGP---PGPAGFPGAPGQNGEPGGKGER 827 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 G G+ G G PG GP G G G G +G +GE+G G G GFPG G+ G G Sbjct: 828 GAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSN 887 Query: 206 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGP---PGKPGPSGQPGRPGPPGPP-PA 261 G G PG +G G G PG G G G GV GP G+PG G PG GPPG P P Sbjct: 888 GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947 Query: 262 GQLIMGPKGERGFPGPPG 279 G I G G RG GPPG Sbjct: 948 G--IAGITGARGLAGPPG 963 Score = 168 bits (426), Expect = 8e-42 Identities = 106/257 (41%), Positives = 125/257 (48%), Gaps = 28/257 (10%) Query: 46 PPPPPL---FP-PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPG 101 PP PP FP P +G P SP + G+ G PGPPG G PG Sbjct: 334 PPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPG 393 Query: 102 LPGKTGPKGEKGELGRPGRKGRPGPPGV---PGMPGPIGWPGPEG------PRGEKGDLG 152 G+ GP G G G G +G PGP G PG+ G G PG G PRGE+G+ G Sbjct: 394 GKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAG 453 Query: 153 MMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPG 212 + G+PG++G G G PG G G G G+ G G +G G G+ G+KG G +G PG Sbjct: 454 IPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG 513 Query: 213 IAGHRGPTGRPGK---------RGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-PAG 262 AG RG G PG+ RG G G G G PG PG G+ GRPGPPGP P G Sbjct: 514 PAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRG 573 Query: 263 QLIMGPKGERGFPGPPG 279 Q G GFPGP G Sbjct: 574 Q-----PGVMGFPGPKG 585 Score = 164 bits (415), Expect = 2e-40 Identities = 85/192 (44%), Positives = 102/192 (53%), Gaps = 6/192 (3%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG 140 SP +G G G PG G PG PG GP G G+ G G G GP G PG G G PG Sbjct: 1027 SPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG 1086 Query: 141 PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLG 200 P+GPRG+KG+ G G G +G G G PG+ G G G++G +G PG G G Sbjct: 1087 PQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGS------PGPAGPRG 1140 Query: 201 QKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPP 260 G GP G+ G +GH GP G PG RG +G++G G G PG+PGP G PG PGP Sbjct: 1141 PVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGV 1200 Query: 261 AGQLIMGPKGER 272 I G GE+ Sbjct: 1201 GAAAIAGIGGEK 1212 Score = 115 bits (288), Expect = 8e-26 Identities = 84/239 (35%), Positives = 100/239 (41%), Gaps = 38/239 (15%) Query: 94 PGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGM 153 P P+ P G P+ P +G GP G PG PG G G G G+ G G Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134 Query: 154 MGLPG-----SRGPM------------------GSKGYPGSRGEKGSRGEKGDLGPKGEK 190 G PG GP G GYPG G G G G G G Sbjct: 135 PGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSP 194 Query: 191 GFPGF---PGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPS 247 G PG+ PG GQ G GP G PG G GP G+ G+ G+ G+ G+ G+ GPPG GP+ Sbjct: 195 GSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPA 254 Query: 248 GQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGES-VYGPSSPR 305 G PG PG G + G GE+G G PG + N GE+ GP PR Sbjct: 255 GIPGFPGMKG----HRGFDGRNGEKGETGAPG-------LKGENGLPGENGAPGPMGPR 302 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 193 bits (491), Expect = 2e-49 Identities = 108/231 (46%), Positives = 125/231 (54%), Gaps = 34/231 (14%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P +QGS G GPPGPQGP GLPG G +G++G G+PG G PG G PG+PGP G GP Sbjct: 662 PGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGP 721 Query: 142 ------------EGPRGEKGDLGM---MGLPGS---------------RGPMGSKGYPGS 171 GPRGE G +G+ GLPG RGP G G PGS Sbjct: 722 PGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGS 781 Query: 172 RGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQ 231 GE G G G G KGE G PG PG LG +G G GE G+ G G G+PG+ G +G+ Sbjct: 782 PGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGE 841 Query: 232 KGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPK---GERGFPGPPG 279 +GD G+ G G PG GQPG PG PG L MGP+ GE G GPPG Sbjct: 842 RGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGL-MGPQGLPGENGPVGPPG 891 Score = 187 bits (475), Expect = 2e-47 Identities = 111/264 (42%), Positives = 126/264 (47%), Gaps = 37/264 (14%) Query: 39 KACCLLTPPPPPLFPP-PFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQ 97 K C PP PP P P F+G + P + +G G GPPG Sbjct: 558 KDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGT------------EGKKGEAGPPGLP 605 Query: 98 GPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP---------------- 141 GPPG+ G G +GE+G G G+KG G PGVPG GP G PGP Sbjct: 606 GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ 665 Query: 142 -----EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 EGP G +G G+ G+PG G G G PG GE G GE G GP+G +G PGF Sbjct: 666 GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 725 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 G G G GP+GE G G G G PGK G G G G GP G PG +G PG PG P Sbjct: 726 GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEP 785 Query: 257 GPP-PAGQLIMGPKGERGFPGPPG 279 GP GQ G KGE G PG PG Sbjct: 786 GPSGTPGQ--KGSKGENGSPGLPG 807 Score = 174 bits (441), Expect = 1e-43 Identities = 108/263 (41%), Positives = 134/263 (50%), Gaps = 25/263 (9%) Query: 34 KRGGHKACCLLTPPPPP----LFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLG 89 +R +A C+L P L P RG P ++ + E + P +G G Sbjct: 227 QRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 286 Query: 90 SPGPPGPQGPPGLPGKTGPKGEKGELGRPG------RKGRPGPPGVPGMPGPIG------ 137 PG PG PG+ G+ G +GEKGELG PG KG GP G PG+PG Sbjct: 287 LPGAPGF---PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHP 343 Query: 138 -WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 PG +GP+GEKGD G+ G PG +G G G G G G++G++G G G G PG P Sbjct: 344 RMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAP 403 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 G +G GP G PG G G G PGK G++G+KG +G G PG GP G PG PG P Sbjct: 404 GHVGAP---GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLP 460 Query: 257 GPPPAGQLIMGPKGERGFPGPPG 279 GPP G+ G G RG PG PG Sbjct: 461 GPPGKGK--DGEPGLRGSPGLPG 481 Score = 172 bits (435), Expect = 7e-43 Identities = 101/259 (38%), Positives = 128/259 (49%), Gaps = 31/259 (11%) Query: 48 PPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTG 107 PP L PP G + + + P + G +G PG PGP G G+ G G Sbjct: 601 PPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAG 660 Query: 108 PKGEKGELGRPGRKGRPGPPGVPGMPGP------IGWPGPEGPRGEKGDLGMMGLPGSRG 161 P G +G G+ G G GP G+PG+PG G PGP G G+ G+ G+ G G+RG Sbjct: 661 PPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 720 Query: 162 PMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPK---------GEPG 212 P G KG+ G G G RGE G +G G++G PG G G G GP+ G PG Sbjct: 721 PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG 780 Query: 213 IAGHRGPTGRPGKRGKQGQKGDSGV------MGPPGKPGPSGQPGRPGPPGPPPAGQLIM 266 G GP+G PG++G +G+ G G+ GPPG+PG G PG+ G PG P Sbjct: 781 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE----P 836 Query: 267 GPKGERGFP------GPPG 279 G KGERG P GPPG Sbjct: 837 GFKGERGDPGIKGDKGPPG 855 Score = 169 bits (428), Expect = 5e-42 Identities = 107/265 (40%), Positives = 124/265 (46%), Gaps = 64/265 (24%) Query: 79 SQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 S +P +G G+ G PG +G PG G TGP G +G G G G+ G PG PG PGP G Sbjct: 731 SGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT 790 Query: 139 PGPE---------------GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD 183 PG + GPRG G+ G G+PG G G G PG +GE+G G KGD Sbjct: 791 PGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGD 850 Query: 184 LGPKGEKGFPGFPGMLGQKGE---MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDS----- 235 GP G KG PG PG+ G KG MGP+G PG G GP G PG+ G G +G+S Sbjct: 851 KGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMET 910 Query: 236 ---------------------------------GVMGPPGKPGPSGQPGRPGP---PGPP 259 G GPPG PG G PGR GP PG P Sbjct: 911 LRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRP 970 Query: 260 PAGQL-----IMGPKGERGFPGPPG 279 G L +GPKGERG G PG Sbjct: 971 GQGGLEGPSGPIGPKGERGAKGDPG 995 Score = 166 bits (420), Expect = 4e-41 Identities = 106/285 (37%), Positives = 122/285 (42%), Gaps = 98/285 (34%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGP--KGEKGELGRPGRKGRPGP---------PGVPGMPG 134 G GSPGP GP+G PG PG GP KG+ GE G G G PGP PG+PG PG Sbjct: 440 GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPG 499 Query: 135 P--------IGWPGPEGPRGEKGDLGMMGLPGSRGPM----------------------- 163 G PGP GP G+KG G GLPG GP Sbjct: 500 SRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKD 559 Query: 164 -------------------GSKGYPGSRGEKGSRGEKGDLGP------------------ 186 G KG PG G +G+ G+KG+ GP Sbjct: 560 VCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGE 619 Query: 187 ---------KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGP---TGRPGKRGKQGQKGD 234 KG++G PG PG +G G GP G GIAG GP G PGK G G +G Sbjct: 620 RGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGP 679 Query: 235 SGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 SG+ G PG+ G G+ G+PGPPG P G GE G PGP G Sbjct: 680 SGLPGIPGEEGKEGRDGKPGPPGEP-------GKAGEPGLPGPEG 717 Score = 164 bits (416), Expect = 1e-40 Identities = 99/228 (43%), Positives = 111/228 (48%), Gaps = 31/228 (13%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG- 140 P +QG G GP GP GPPG G+ G G G G PG G G PG G PG +G PG Sbjct: 364 PGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGL 423 Query: 141 --PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 G GE+G+ G G GS GP+G +G PG+ G G G KG G G +G PG PG Sbjct: 424 RGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGP 482 Query: 199 LGQKGEMGPKGEPGIAGHRGP-----TGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRP 253 LG KG+ G G PG G RG G PG G G KG G G PG PGP G GR Sbjct: 483 LGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRD 542 Query: 254 G---------------------PPGPPPAGQLIMGPKGERGFPGPPGR 280 G PPGPP L G KG++G PG PGR Sbjct: 543 GLSSLLSPGDINLLAKDVCNDCPPGPPGLPGL-PGFKGDKGVPGKPGR 589 Score = 161 bits (407), Expect = 1e-39 Identities = 109/281 (38%), Positives = 125/281 (44%), Gaps = 54/281 (19%) Query: 48 PPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPG---LPG 104 PP P G P +P K E + P G G PG PG +G PG +PG Sbjct: 772 PPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPG 831 Query: 105 KTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMG 164 K G G KGE G PG KG GPPG G PG PG G +G G +G GLPG GP+G Sbjct: 832 KPGEPGFKGERGDPGIKGDKGPPGGKGQPGD---PGIPGHKGHTGLMGPQGLPGENGPVG 888 Query: 165 SKGYPGSRGEKGSRGE-----------------------------------KGDLGPKGE 189 G PG G G RGE K G G Sbjct: 889 PPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGP 948 Query: 190 KGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGV--------MGPP 241 G PG G+ G+ G MG G PG G GP+G G +G++G KGD G MGPP Sbjct: 949 PGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPP 1008 Query: 242 GKPGPSGQPG--RPGPPG-PPPAGQLIMGPKGERGFPGPPG 279 G PG G+PG + G PG P P G+ GP G G PGPPG Sbjct: 1009 GIPGQPGEPGYAKDGLPGIPGPQGE--TGPAGHPGLPGPPG 1047 Score = 160 bits (404), Expect = 3e-39 Identities = 102/279 (36%), Positives = 119/279 (42%), Gaps = 83/279 (29%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPG---MPGPIGWPGPE 142 G GSPG PG GP G PG+ G KGE G G PG G GPPG PG +PG G PG Sbjct: 774 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 833 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRG------------EKGDLGPKGEK 190 G G KG+ G G+ G +GP G KG PG G G +G E G +GP G Sbjct: 834 GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPP 893 Query: 191 GFPGFPGMLGQKGEM-----------------------------------------GPKG 209 G PGFPG+ G+ M GP G Sbjct: 894 GQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPG 953 Query: 210 EPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPG--------PPGPP-- 259 + G+ G GP G PG+ G+ G +G SG +GP G+ G G PG PG PPG P Sbjct: 954 KDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQ 1013 Query: 260 --------------PAGQLIMGPKGERGFPG---PPGRC 281 P Q GP G G PG PPG+C Sbjct: 1014 PGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQC 1052 Score = 130 bits (328), Expect = 2e-30 Identities = 93/272 (34%), Positives = 109/272 (40%), Gaps = 68/272 (25%) Query: 45 TPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 +P P P +G + SP + + P +G G G PG G PG G Sbjct: 781 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKG 840 Query: 105 KTGPKGEKGELGRPGRKGRPGPPGVPGM---------------------PGPIGWPGPEG 143 + G G KG+ G PG KG+PG PG+PG PGP G PG G Sbjct: 841 ERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPG 900 Query: 144 PRGEK--------------------------------------------GDLGMMGLPGS 159 RGE G G GLPG Sbjct: 901 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 960 Query: 160 RGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRG- 218 GPMG G PG G +G G G G +G KG PG PG+ G +GEMGP G PG G G Sbjct: 961 AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPGY 1019 Query: 219 -PTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQ 249 G PG G QG+ G +G G PG PGP GQ Sbjct: 1020 AKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1051 Score = 107 bits (266), Expect = 3e-23 Identities = 81/197 (41%), Positives = 91/197 (46%), Gaps = 35/197 (17%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLML--------ELET------SQSP--CMQGSLG 89 PP PP P F G R SP M+ L +LET +Q P M+ S G Sbjct: 889 PPGPP--GQPGFPGLRGE--SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQG 944 Query: 90 SPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKG 149 PGPPGP G GLPG+ GP GE PG PG G+ GP G GP+G RG KG Sbjct: 945 RPGPPGPPGKDGLPGRAGPMGE------------PGRPGQGGLEGPSGPIGPKGERGAKG 992 Query: 150 DLGMMGLPGSRGPMGSKGYPGSRGEKG--SRGEKGDLGPKGEKGFPGFPGMLGQKGEMGP 207 D G G+ G RG MG G PG GE G G G GP+GE G G PG+ G G G Sbjct: 993 DPGAPGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1051 Query: 208 KGEPGIAGHRGPTGRPG 224 A RPG Sbjct: 1052 CDPSQCAYFASLAARPG 1068 Score = 104 bits (259), Expect = 2e-22 Identities = 73/203 (35%), Positives = 92/203 (45%), Gaps = 33/203 (16%) Query: 98 GPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVP-GMPGPIGWP-----GPEGPRGEKGDL 151 GP P + +G +G GR P MP G G +GP ++ D Sbjct: 172 GPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADA 231 Query: 152 G---------------MMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 + G PG RG G G PG RGE G +G G G KGE G PG P Sbjct: 232 RASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAP 291 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 G G +GE G +GE +G G PG +G +G+KG++G GPPG PG + P Sbjct: 292 GFPGVRGEKGDQGE------KGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL----FTP 341 Query: 257 GPPPAGQLIMGPKGERGFPGPPG 279 P G+ GPKGE+G PG PG Sbjct: 342 HPRMPGE--QGPKGEKGDPGLPG 362 Score = 59.3 bits (142), Expect = 7e-09 Identities = 35/86 (40%), Positives = 45/86 (52%), Gaps = 8/86 (9%) Query: 85 QGSLGSPGPPG-----PQGPPGLPGKTGPKG--EKGELGRPGRKGRPGPPGVPGMPGPIG 137 +G+ G PG PG GPPG+PG+ G G + G G PG +G GP G PG+PGP G Sbjct: 988 RGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPG 1047 Query: 138 WPGPEGPRGEKGDLGMMGLPGS-RGP 162 PG P + PG+ +GP Sbjct: 1048 PPGQCDPSQCAYFASLAARPGNVKGP 1073 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 193 bits (491), Expect = 2e-49 Identities = 108/231 (46%), Positives = 125/231 (54%), Gaps = 34/231 (14%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P +QGS G GPPGPQGP GLPG G +G++G G+PG G PG G PG+PGP G GP Sbjct: 1215 PGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGP 1274 Query: 142 ------------EGPRGEKGDLGM---MGLPGS---------------RGPMGSKGYPGS 171 GPRGE G +G+ GLPG RGP G G PGS Sbjct: 1275 PGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGS 1334 Query: 172 RGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQ 231 GE G G G G KGE G PG PG LG +G G GE G+ G G G+PG+ G +G+ Sbjct: 1335 PGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGE 1394 Query: 232 KGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPK---GERGFPGPPG 279 +GD G+ G G PG GQPG PG PG L MGP+ GE G GPPG Sbjct: 1395 RGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGL-MGPQGLPGENGPVGPPG 1444 Score = 187 bits (475), Expect = 2e-47 Identities = 111/264 (42%), Positives = 126/264 (47%), Gaps = 37/264 (14%) Query: 39 KACCLLTPPPPPLFPP-PFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQ 97 K C PP PP P P F+G + P + +G G GPPG Sbjct: 1111 KDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGT------------EGKKGEAGPPGLP 1158 Query: 98 GPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP---------------- 141 GPPG+ G G +GE+G G G+KG G PGVPG GP G PGP Sbjct: 1159 GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ 1218 Query: 142 -----EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 EGP G +G G+ G+PG G G G PG GE G GE G GP+G +G PGF Sbjct: 1219 GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 1278 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 G G G GP+GE G G G G PGK G G G G GP G PG +G PG PG P Sbjct: 1279 GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEP 1338 Query: 257 GPP-PAGQLIMGPKGERGFPGPPG 279 GP GQ G KGE G PG PG Sbjct: 1339 GPSGTPGQ--KGSKGENGSPGLPG 1360 Score = 182 bits (461), Expect = 7e-46 Identities = 101/213 (47%), Positives = 122/213 (57%), Gaps = 19/213 (8%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKG---EKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 QG G PGPPG G PGL G+ G KG EKGE G G G+PG G G PGP G GP Sbjct: 571 QGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP 630 Query: 142 EGPRGEKGDLGMMGLPGS----RGPMGSKGYPGSRGEKGSRGE---KGDLGPKGEKGFPG 194 +G +G+ G G G+PGS G G +G PG RG +G+ G +G +GP+G G PG Sbjct: 631 QGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPG 690 Query: 195 FPGMLGQKGEMGPKGEPGIAGHRGPTGRPG------KRGKQGQKGDSGVMGPPGKPGPSG 248 G+ G+KG+MGP G PG+ G +GP G PG G G G+ G G PG PGP+G Sbjct: 691 LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTG 750 Query: 249 QPGRPGPPGPP-PAGQLIMGPKGERGFPGPPGR 280 PG+ GP GPP P G G GERG G PG+ Sbjct: 751 PPGKDGPNGPPGPPGT--KGEPGERGEDGLPGK 781 Score = 177 bits (448), Expect = 2e-44 Identities = 109/267 (40%), Positives = 134/267 (50%), Gaps = 25/267 (9%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 P PP P RG P ++ + E + P +G G PG PG PG+ G+ Sbjct: 761 PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF---PGVRGE 817 Query: 106 TGPKGEKGELGRPG------RKGRPGPPGVPGMPGPIG-------WPGPEGPRGEKGDLG 152 G +GEKGELG PG KG GP G PG+PG PG +GP+GEKGD G Sbjct: 818 KGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPG 877 Query: 153 MMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPG 212 + G PG +G G G G G G++G++G G G G PG PG +G GP G PG Sbjct: 878 LPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP---GPSGPPG 934 Query: 213 IAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGER 272 G G G PGK G++G+KG +G G PG GP G PG PG PGPP G+ G G R Sbjct: 935 SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGK--DGEPGLR 992 Query: 273 GFPGPPG----RCLCGPTMNVNNPSYG 295 G PG PG + CG N + G Sbjct: 993 GSPGLPGPLGTKAACGKVRGSENCALG 1019 Score = 176 bits (445), Expect = 5e-44 Identities = 124/333 (37%), Positives = 146/333 (43%), Gaps = 87/333 (26%) Query: 43 LLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGL 102 ++T PPPP PPP R P + + + S +G +G GP G GP G Sbjct: 447 VVTEPPPP--PPP----QRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGD 500 Query: 103 PGKTGP----------------------KGEKGELGRPGRKGR---------PGPPGVPG 131 G GP KGEKG LG PG GR PG G PG Sbjct: 501 IGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPG 560 Query: 132 MPGPIGWPGPEGP------------------------RGEKGDLGMMGLPGSRGPMGSKG 167 +PG +G GP+GP RGEKG+ G+ G PG G G +G Sbjct: 561 LPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG 620 Query: 168 YPGSRGEKGSRGEKGDLGPKGEKGFPGF----PGMLGQKGEMGPKGE------PGIAGHR 217 PG G G +GEKGD+GP G G PG G+ G++G GP+G PG G Sbjct: 621 RPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPI 680 Query: 218 GPTGRPGKRGKQGQKGDSGVMGPPGKP------GPSGQPGRPGPPGPPPAGQLIMGPKGE 271 GP GR G G QG +G G MGPPG P GP G PG PGPPGP + G GE Sbjct: 681 GPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGS----PGLPGE 736 Query: 272 RGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 GFPG PG GPT P + GP P Sbjct: 737 IGFPGKPGP--PGPT----GPPGKDGPNGPPGP 763 Score = 174 bits (441), Expect = 1e-43 Identities = 105/259 (40%), Positives = 131/259 (50%), Gaps = 25/259 (9%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQ----SPCMQGSLGSPGPPGPQGPPG 101 P P + P +G P P + +++ E + +P +G G+PGPPG +GP G Sbjct: 622 PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIG 681 Query: 102 LPGKTGP------KGEKGELGRPG------RKGRPGPPGVPGMPGP---------IGWPG 140 G+ GP +G+KG++G PG +G PGPPGVPG PGP IG+PG Sbjct: 682 PEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPG 741 Query: 141 PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLG 200 GP G G G G G GP G+KG PG RGE G G+ G G GE+G G PG G Sbjct: 742 KPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKG 801 Query: 201 QKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPP 260 + G G G PG+ G +G G G+ G G KGD G G G GP G PG P P Sbjct: 802 EAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHP 861 Query: 261 AGQLIMGPKGERGFPGPPG 279 GPKGE+G PG PG Sbjct: 862 RMPGEQGPKGEKGDPGLPG 880 Score = 174 bits (440), Expect = 2e-43 Identities = 102/245 (41%), Positives = 119/245 (48%), Gaps = 54/245 (22%) Query: 82 PCMQGSLGSPG-----PPGPQGPP---------GLPGKTGPKGEKGELGRPGRKGRPGPP 127 P GS G PG PPGP GPP GLPG GP+G G G PG G GPP Sbjct: 1033 PGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPP 1092 Query: 128 GVPGM---------------------PGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSK 166 G PG+ PGP G PG G +G+KG G G G+ G G Sbjct: 1093 GKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEA 1152 Query: 167 GYP---------GSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHR 217 G P G +G +G RG G++G KG++G PG PG +G G GP G GIAG Sbjct: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 1212 Query: 218 GP---TGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGF 274 GP G PGK G G +G SG+ G PG+ G G+ G+PGPPG P G GE G Sbjct: 1213 GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEP-------GKAGEPGL 1265 Query: 275 PGPPG 279 PGP G Sbjct: 1266 PGPEG 1270 Score = 172 bits (435), Expect = 7e-43 Identities = 101/259 (38%), Positives = 128/259 (49%), Gaps = 31/259 (11%) Query: 48 PPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTG 107 PP L PP G + + + P + G +G PG PGP G G+ G G Sbjct: 1154 PPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAG 1213 Query: 108 PKGEKGELGRPGRKGRPGPPGVPGMPGP------IGWPGPEGPRGEKGDLGMMGLPGSRG 161 P G +G G+ G G GP G+PG+PG G PGP G G+ G+ G+ G G+RG Sbjct: 1214 PPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 1273 Query: 162 PMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPK---------GEPG 212 P G KG+ G G G RGE G +G G++G PG G G G GP+ G PG Sbjct: 1274 PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG 1333 Query: 213 IAGHRGPTGRPGKRGKQGQKGDSGV------MGPPGKPGPSGQPGRPGPPGPPPAGQLIM 266 G GP+G PG++G +G+ G G+ GPPG+PG G PG+ G PG P Sbjct: 1334 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE----P 1389 Query: 267 GPKGERGFP------GPPG 279 G KGERG P GPPG Sbjct: 1390 GFKGERGDPGIKGDKGPPG 1408 Score = 169 bits (428), Expect = 5e-42 Identities = 107/265 (40%), Positives = 124/265 (46%), Gaps = 64/265 (24%) Query: 79 SQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 S +P +G G+ G PG +G PG G TGP G +G G G G+ G PG PG PGP G Sbjct: 1284 SGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT 1343 Query: 139 PGPE---------------GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD 183 PG + GPRG G+ G G+PG G G G PG +GE+G G KGD Sbjct: 1344 PGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGD 1403 Query: 184 LGPKGEKGFPGFPGMLGQKGE---MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDS----- 235 GP G KG PG PG+ G KG MGP+G PG G GP G PG+ G G +G+S Sbjct: 1404 KGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMET 1463 Query: 236 ---------------------------------GVMGPPGKPGPSGQPGRPGP---PGPP 259 G GPPG PG G PGR GP PG P Sbjct: 1464 LRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRP 1523 Query: 260 PAGQL-----IMGPKGERGFPGPPG 279 G L +GPKGERG G PG Sbjct: 1524 GQGGLEGPSGPIGPKGERGAKGDPG 1548 Score = 166 bits (421), Expect = 3e-41 Identities = 100/238 (42%), Positives = 122/238 (51%), Gaps = 28/238 (11%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 P PP P P R G +P ++ E T +G G PG PG G G PG Sbjct: 570 PQGPPGLPGPPGRVG-----APGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGP 624 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPI----GWPGPEGPRGEKGDLGMMGLPGSRG 161 +G G +GE KG GP G PG+PG + G G +G G +G G G PG+RG Sbjct: 625 SGVAGPQGE------KGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARG 678 Query: 162 PMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTG 221 P+G +G G G +G RG+KGD+GP PG PG+LG +G GP G PG G G G Sbjct: 679 PIGPEGRDGPPGLQGLRGKKGDMGP------PGIPGLLGLQGPPGPPGVPGPPGPGGSPG 732 Query: 222 RPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 PG+ G G+ G G GPPGK GP+G PG PG G P G +GE G PG PG Sbjct: 733 LPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEP-------GERGEDGLPGKPG 783 Score = 166 bits (420), Expect = 4e-41 Identities = 101/245 (41%), Positives = 120/245 (48%), Gaps = 40/245 (16%) Query: 75 ELETS----QSPCMQGSLGSPGPPGPQGPPGLPGK-----------TGPKGEKGELGRPG 119 ELET PC + P PP P P PG + P GEKGE+G G Sbjct: 431 ELETCCDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAG 490 Query: 120 RKGRPGPPGVPGMPGPIGWPGP-------------EGPRGEKGDLGMMGLPGSRGPMGSK 166 G PGP G G GP+G PGP +G +GEKG LG+ G PG G G + Sbjct: 491 PMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMR 550 Query: 167 GYPGSRGEKGSRGEKGDLGPKGEKGFP------GFPGMLGQKGEMGPKGEPGIAGHRGPT 220 G PG GE G GE G GP+G G P G PG+ G++GE G +GE G G G Sbjct: 551 GEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFP 610 Query: 221 GRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP------PAGQLIMGPKGERGF 274 G+PG G+QG+ G SGV GP G+ G G G PG PG Q GP+G +G Sbjct: 611 GKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGA 670 Query: 275 PGPPG 279 PGPPG Sbjct: 671 PGPPG 675 Score = 162 bits (410), Expect = 6e-40 Identities = 104/246 (42%), Positives = 118/246 (47%), Gaps = 48/246 (19%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKT-------------GPKGEKGELGRPGRKGRPGPPG 128 P ++G G G GP GPPGLPG T GPKGEKG+ G PG G G PG Sbjct: 830 PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPG 889 Query: 129 VPGMPGPIGWPGPEGPRGEKGDLGM---------MGLPGSRGPMGSKGYPG--------- 170 G GP G PG +G G G G +G PG GP GS G PG Sbjct: 890 ELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 949 Query: 171 SRGEKGSRGEKGDLGPKGEKGFPGFPGM-----LGQKGEMGPKGEPGIAGHRGPTGRPGK 225 RGEKG+ GE+G GP G +G PG PG+ G+ GE G +G PG+ G G GK Sbjct: 950 ERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGK 1009 Query: 226 --------RGKQGQKGDSGVMGPPGKPGPSGQP--GRPGPPGP--PPAGQLIMGPKGERG 273 G Q KGD G G PG PG G P G GPPGP PP + G +G G Sbjct: 1010 VRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPG 1069 Query: 274 FPGPPG 279 FPGP G Sbjct: 1070 FPGPQG 1075 Score = 161 bits (407), Expect = 1e-39 Identities = 109/281 (38%), Positives = 125/281 (44%), Gaps = 54/281 (19%) Query: 48 PPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPG---LPG 104 PP P G P +P K E + P G G PG PG +G PG +PG Sbjct: 1325 PPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPG 1384 Query: 105 KTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMG 164 K G G KGE G PG KG GPPG G PG PG G +G G +G GLPG GP+G Sbjct: 1385 KPGEPGFKGERGDPGIKGDKGPPGGKGQPGD---PGIPGHKGHTGLMGPQGLPGENGPVG 1441 Query: 165 SKGYPGSRGEKGSRGE-----------------------------------KGDLGPKGE 189 G PG G G RGE K G G Sbjct: 1442 PPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGP 1501 Query: 190 KGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGV--------MGPP 241 G PG G+ G+ G MG G PG G GP+G G +G++G KGD G MGPP Sbjct: 1502 PGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPP 1561 Query: 242 GKPGPSGQPG--RPGPPG-PPPAGQLIMGPKGERGFPGPPG 279 G PG G+PG + G PG P P G+ GP G G PGPPG Sbjct: 1562 GIPGQPGEPGYAKDGLPGIPGPQGE--TGPAGHPGLPGPPG 1600 Score = 160 bits (404), Expect = 3e-39 Identities = 102/279 (36%), Positives = 119/279 (42%), Gaps = 83/279 (29%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPG---MPGPIGWPGPE 142 G GSPG PG GP G PG+ G KGE G G PG G GPPG PG +PG G PG Sbjct: 1327 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 1386 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRG------------EKGDLGPKGEK 190 G G KG+ G G+ G +GP G KG PG G G +G E G +GP G Sbjct: 1387 GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPP 1446 Query: 191 GFPGFPGMLGQKGEM-----------------------------------------GPKG 209 G PGFPG+ G+ M GP G Sbjct: 1447 GQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPG 1506 Query: 210 EPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPG--------PPGPP-- 259 + G+ G GP G PG+ G+ G +G SG +GP G+ G G PG PG PPG P Sbjct: 1507 KDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQ 1566 Query: 260 --------------PAGQLIMGPKGERGFPG---PPGRC 281 P Q GP G G PG PPG+C Sbjct: 1567 PGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQC 1605 Score = 156 bits (395), Expect = 3e-38 Identities = 105/270 (38%), Positives = 118/270 (43%), Gaps = 79/270 (29%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGP--KGEKGELGRPGRKGRPGP----------------- 126 G GSPGP GP+G PG PG GP KG+ GE G G G PGP Sbjct: 958 GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCA 1017 Query: 127 ------------PGVPGMPGP--------IGWPGPEGPRGEKGDLGMMGLPG---SRGPM 163 PG+PG PG G PGP GP G+KG G GLPG +GP Sbjct: 1018 LGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPA 1077 Query: 164 GSKGYPGSRGEKGSRGEKG-------------------DLGP-----------KGEKGFP 193 G G PG+ GE+G G+ G D P KG+KG P Sbjct: 1078 GRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVP 1137 Query: 194 GFPGMLG---QKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 G PG G +KGE GP G PG G GP G G+RG G+ G G G PG PG G P Sbjct: 1138 GKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPP 1197 Query: 251 GRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 G PGPPG I G G G G PG+ Sbjct: 1198 GNPGPPGADG----IAGAAGPPGIQGSPGK 1223 Score = 155 bits (392), Expect = 7e-38 Identities = 102/266 (38%), Positives = 116/266 (43%), Gaps = 72/266 (27%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGR------PGPPGVPGMPGP 135 P +QG G GP GP GPPG G+ G G G G PG G GPPG G PG Sbjct: 882 PGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGL 941 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPG--------SRGEKGSRGEKGDLGP- 186 G PG +G RGEKG G G PG GP G G PG GE G RG G GP Sbjct: 942 RGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPL 1001 Query: 187 ----------------------KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPG 224 KG++G PG PG G +G+ G G+AG GP+G PG Sbjct: 1002 GTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI----GVAGPPGPSGPPG 1057 Query: 225 KRGKQGQKGDSGVMGP---------PGKPGPSGQPGRPG--------------------- 254 +G G +G G GP PG PG G PG+PG Sbjct: 1058 DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC 1117 Query: 255 PPGPPPAGQLIMGPKGERGFPGPPGR 280 PPGPP L G KG++G PG PGR Sbjct: 1118 PPGPPGLPGL-PGFKGDKGVPGKPGR 1142 Score = 130 bits (328), Expect = 2e-30 Identities = 93/272 (34%), Positives = 109/272 (40%), Gaps = 68/272 (25%) Query: 45 TPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 +P P P +G + SP + + P +G G G PG G PG G Sbjct: 1334 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKG 1393 Query: 105 KTGPKGEKGELGRPGRKGRPGPPGVPGM---------------------PGPIGWPGPEG 143 + G G KG+ G PG KG+PG PG+PG PGP G PG G Sbjct: 1394 ERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453 Query: 144 PRGEK--------------------------------------------GDLGMMGLPGS 159 RGE G G GLPG Sbjct: 1454 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 1513 Query: 160 RGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRG- 218 GPMG G PG G +G G G G +G KG PG PG+ G +GEMGP G PG G G Sbjct: 1514 AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPGY 1572 Query: 219 -PTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQ 249 G PG G QG+ G +G G PG PGP GQ Sbjct: 1573 AKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604 Score = 107 bits (266), Expect = 3e-23 Identities = 81/197 (41%), Positives = 91/197 (46%), Gaps = 35/197 (17%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLML--------ELET------SQSP--CMQGSLG 89 PP PP P F G R SP M+ L +LET +Q P M+ S G Sbjct: 1442 PPGPP--GQPGFPGLRGE--SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQG 1497 Query: 90 SPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKG 149 PGPPGP G GLPG+ GP GE PG PG G+ GP G GP+G RG KG Sbjct: 1498 RPGPPGPPGKDGLPGRAGPMGE------------PGRPGQGGLEGPSGPIGPKGERGAKG 1545 Query: 150 DLGMMGLPGSRGPMGSKGYPGSRGEKG--SRGEKGDLGPKGEKGFPGFPGMLGQKGEMGP 207 D G G+ G RG MG G PG GE G G G GP+GE G G PG+ G G G Sbjct: 1546 DPGAPGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604 Query: 208 KGEPGIAGHRGPTGRPG 224 A RPG Sbjct: 1605 CDPSQCAYFASLAARPG 1621 Score = 59.3 bits (142), Expect = 7e-09 Identities = 35/86 (40%), Positives = 45/86 (52%), Gaps = 8/86 (9%) Query: 85 QGSLGSPGPPG-----PQGPPGLPGKTGPKG--EKGELGRPGRKGRPGPPGVPGMPGPIG 137 +G+ G PG PG GPPG+PG+ G G + G G PG +G GP G PG+PGP G Sbjct: 1541 RGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPG 1600 Query: 138 WPGPEGPRGEKGDLGMMGLPGS-RGP 162 PG P + PG+ +GP Sbjct: 1601 PPGQCDPSQCAYFASLAARPGNVKGP 1626 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 192 bits (488), Expect = 5e-49 Identities = 107/245 (43%), Positives = 134/245 (54%), Gaps = 16/245 (6%) Query: 48 PPPLFPPPFFRGGRSPLLSP--DMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 PP L PP +G + P DM + P + G G PG PG QG PG+PG Sbjct: 815 PPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGF 874 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIG---WPGPEGPRGE------KGDLGMMGL 156 G KGE G +G PG+ G PGP G PG+PG G +PG GPRG+ KGD+G+ G Sbjct: 875 PGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGK 934 Query: 157 PGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGH 216 PGS + G +G++G +G+ G +G KG +G PG PG+ G+ G+ G G+PG G Sbjct: 935 PGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGD 994 Query: 217 RGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP--PAGQLIMGPKGERGF 274 G +G PG G G KG G MG PG PG G PG PGP G P P + G KGE+G Sbjct: 995 PGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDK---GAKGEKGQ 1051 Query: 275 PGPPG 279 GPPG Sbjct: 1052 AGPPG 1056 Score = 181 bits (460), Expect = 9e-46 Identities = 118/280 (42%), Positives = 131/280 (46%), Gaps = 54/280 (19%) Query: 54 PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKG 113 PP +G P K S P G G PG GP GPPG+PG G KGE+G Sbjct: 74 PPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERG 133 Query: 114 ELGRPGR---KGRPGPPGVPGM---PGPI----------------GWPGPEGPRGEKGDL 151 LG PG G PGPPG+PGM PG I G PG GP G G Sbjct: 134 PLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQ 193 Query: 152 GMMGLPGSRGPMGSKGYPGSRGEKGS-----RGEKGDLGPKGEKGFPGFPGM-------- 198 G +G PG GP G G PG GEKG +G KGD G +G G PG PG Sbjct: 194 GPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGD 253 Query: 199 LGQKGEMGPKGEPGI-----AGHRGPTGRPGKRGKQGQKGDSGVMGPPGKP--------- 244 KGE G KGEPG G +G G+PG RGK G+ GD G G PG P Sbjct: 254 FATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLI 313 Query: 245 ---GPSGQPGRPGPPGPP--PAGQLIMGPKGERGFPGPPG 279 GP G+ G GPPGPP G +G KGERG+PG PG Sbjct: 314 GRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPG 353 Score = 181 bits (459), Expect = 1e-45 Identities = 117/280 (41%), Positives = 134/280 (47%), Gaps = 49/280 (17%) Query: 45 TPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGL-- 102 TP P L P GG +P K + SP + G G+ G G GPPG+ Sbjct: 1000 TPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGI 1059 Query: 103 ---------------PGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGE 147 PG G KGEKG +G P G PG PG+ G PG +G+PG G GE Sbjct: 1060 PGLRGEKGDQGIAGFPGSPGEKGEKGSIGIP---GMPGSPGLKGSPGSVGYPGSPGLPGE 1116 Query: 148 KGDLGMMGL---------------PGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGF 192 KGD G+ GL PG GP G KG PGS G GS GEKG+ G G +GF Sbjct: 1117 KGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPG-RGF 1175 Query: 193 PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKP-------- 244 PGFPG G KG G G PG+AG G G G++G G G G G PG P Sbjct: 1176 PGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPK 1235 Query: 245 ---GPSGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 GP GQPG PG PGP PP I G KG++G PG PG Sbjct: 1236 GDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPG 1275 Score = 180 bits (456), Expect = 3e-45 Identities = 110/249 (44%), Positives = 127/249 (51%), Gaps = 51/249 (20%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P G G PG PG +G PG PG G KG KGE+G PG G PG PG G G +G PGP Sbjct: 1159 PGSAGEKGEPGLPG-RGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGP 1217 Query: 142 --------------EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKG----- 182 EGP+G++G G GLPG GPMG G PG G KG +G G Sbjct: 1218 QGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAP 1277 Query: 183 -DLGPKGEKGFPGFPGMLGQKGEMGPKGE---PGIAGHRGPTGRPGKRGKQGQKGDSGVM 238 GPKG+ GF G PG+ G G G KG+ PG+ G +GP G PG +G +G +GD GV Sbjct: 1278 GVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVP 1337 Query: 239 G------PPGKPGP----SGQPGRPGPPGPP----------PAGQL-------IMGPKGE 271 G PPG PGP G+PG PGP GPP P GQ I GP G Sbjct: 1338 GAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGI 1397 Query: 272 RGFPGPPGR 280 GF G PG+ Sbjct: 1398 PGFDGAPGQ 1406 Score = 180 bits (456), Expect = 3e-45 Identities = 105/229 (45%), Positives = 121/229 (52%), Gaps = 33/229 (14%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTG-----PKGEKGELGRPGRKGRPGPPGVPGMPG-- 134 P +G G GPPGPQG PGLPG G PKG++G G+PG G PGP G PG+PG Sbjct: 1203 PGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGID 1262 Query: 135 -------PIGWPGPEGPRGEKGDLGMMGLPG---------SRGPMGSKGYPGSRGEKGSR 178 GWPG G G KGD G G+PG S+G MG G PG +G KG Sbjct: 1263 GVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLP 1322 Query: 179 GEKGDLGPKGEKGFPGFPGMLGQKGEMGP----KGEPGIAGHRGPTGRPGKRGKQGQKGD 234 G +G G +G++G PG G+ G G GP KGEPG+ G GP G G +G G KG Sbjct: 1323 GLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQ 1382 Query: 235 SGVMGPPGKPGPSGQPGRPGPPGPP----PAGQLIMGPKGERGFPGPPG 279 GV G G PGP G PG G PG PAG GP+G G PGP G Sbjct: 1383 QGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPT--GPRGFPGPPGPDG 1429 Score = 179 bits (453), Expect = 6e-45 Identities = 119/293 (40%), Positives = 138/293 (47%), Gaps = 39/293 (13%) Query: 50 PLFPP--PFFRGGRSPLLSPDMKNLMLE-LETSQSPCMQGSLGSPGPPGPQGPPGLPGKT 106 PL PP P F G P P MK E L ++G G PG PG GPPGLPG Sbjct: 134 PLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQ 193 Query: 107 GPKGEKGELGRPGRKGRPGPPGVPG-----------------MPGPIGWPGP-------- 141 GP G G G PG G PGPPG G + GP G PG Sbjct: 194 GPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGD 253 Query: 142 ---EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 +G +G+KG+ G G+PG G G G PG RG+ G G+KG+ G G G PG+PG+ Sbjct: 254 FATKGEKGQKGEPGFQGMPGV-GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGL 312 Query: 199 L------GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 + G+KGE GP G PGI GP G G+RG G G G GP G PG GQPG Sbjct: 313 IGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGP 372 Query: 253 PGPPGPPPAGQL-IMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 PG P P AG G +GE+G G PG L GP+ P S P P Sbjct: 373 PGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQP 425 Score = 177 bits (449), Expect = 2e-44 Identities = 100/199 (50%), Positives = 116/199 (58%), Gaps = 6/199 (3%) Query: 91 PGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGD 150 PGPPG +G PG PG GP+G++G G PGR G PG G G PG IG+PGP GP+G G Sbjct: 645 PGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPG-IGFPGPPGPKGVDGL 703 Query: 151 LGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD--LGPKGEKGFPGFPGMLGQKGEMGPK 208 G MG PG+ G G G PG+ G +G +GE G G KG G PG PG G+KG +G Sbjct: 704 PGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVP 763 Query: 209 GEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG--PPPAGQLIM 266 G PG G GP G G RG+ G G G +G PG PG G PG GPPG PP Sbjct: 764 GVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG-IGPPGARGPPGGQGPPGLSGPP 822 Query: 267 GPKGERGFPGPPGRCLCGP 285 G KGE+GFPG PG + GP Sbjct: 823 GIKGEKGFPGFPGLDMPGP 841 Score = 175 bits (443), Expect = 9e-44 Identities = 112/265 (42%), Positives = 128/265 (48%), Gaps = 52/265 (19%) Query: 91 PGPPGPQGPPGLPGKTGPKGEKGELGRPGRK-------GRPGPPGVPGMPGPIGWPGPEG 143 PGPPG QGPPG+PG+ G GE GE G+ G G GPPG G PG IG+PG G Sbjct: 436 PGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPG 495 Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE-KGDLGPKGEKGFPGFPGMLGQK 202 +G++G G G+ G GP G+ G G G KG GE DL KG+KG PGFPG G Sbjct: 496 AKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMT 555 Query: 203 GEM------------GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK------- 243 G GPKG PG G +G G PG G G +GD+G GPPG Sbjct: 556 GRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIG 615 Query: 244 -------PGPSGQPGRPGP----------PGPP-----PAGQLIMGPKGERGFPGPPGR- 280 PG G PG PGP PGPP P GP+G+RGFPG PGR Sbjct: 616 DKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRP 675 Query: 281 CLCGPTMNVNNPSYGESVYGPSSPR 305 L G V P G GP P+ Sbjct: 676 GLPGEKGAVGQPGIG--FPGPPGPK 698 Score = 172 bits (437), Expect = 4e-43 Identities = 104/219 (47%), Positives = 118/219 (53%), Gaps = 22/219 (10%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP----- 135 SP +G GS G PG G PGL G G G G G PG KG G PG+ G+PG Sbjct: 1077 SPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAG 1136 Query: 136 -IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPG 194 G PGP GP G+KG+ G G+PGS G G G PG RG G G KGD G KGE GFPG Sbjct: 1137 LPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPG-RGFPGFPGAKGDKGSKGEVGFPG 1195 Query: 195 F---PGMLGQKGEM------GPKGEPGIAGH-----RGPTGRPGKRGKQGQKGDSGVMGP 240 PG+ G KGE GP+G+PG+ G GP G G +G+ G G G MGP Sbjct: 1196 LAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGP 1255 Query: 241 PGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 PG PG G G G PG P A + GPKG+ GF G PG Sbjct: 1256 PGLPGIDGVKGDKGNPGWPGAPG-VPGPKGDPGFQGMPG 1293 Score = 169 bits (429), Expect = 4e-42 Identities = 104/240 (43%), Positives = 121/240 (50%), Gaps = 46/240 (19%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGE------KGELGRPGRKGRPGPPGVPGMPGP 135 P +QG +G PG GP+GP G PG+ G GE KG G PG G PG PG+PG+PG Sbjct: 54 PGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQ 113 Query: 136 IGWPGP------EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGS-RGEKGDLGPKG 188 G PGP G +GE+G LG GLPG G G G PG +G+ G G + KG Sbjct: 114 DGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKG 173 Query: 189 EKGFPGFPGMLGQ---KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQ-----------KGD 234 E+GFPG PG G G GP G PG G GP G PG G++GQ KGD Sbjct: 174 ERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGD 233 Query: 235 SGVMGPPGKPGPS--------------GQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 GV GPPG PG + GQ G PG G P G+ KGE G PGP G+ Sbjct: 234 QGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGE-----KGEPGKPGPRGK 288 Score = 169 bits (429), Expect = 4e-42 Identities = 115/293 (39%), Positives = 139/293 (47%), Gaps = 67/293 (22%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGP---------------KGEKGELGRPGRKGRPGP 126 P G G PG G +G GLPGK G +GEKG++G G KG G Sbjct: 911 PGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGD 970 Query: 127 PGVPGMP---GPIGWPGPEGPRGE---------------KGDLGMMGLPGSRGPMGSKGY 168 PG PG+P G G PG GP+G+ KG +G MGLPG+ G G G Sbjct: 971 PGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGI 1030 Query: 169 PGSR------GEKGSRGEKGDLGP-----------KGEKGFPGFPGMLGQKGEMGP---- 207 PG + G+KG++GEKG GP KG++G GFPG G+KGE G Sbjct: 1031 PGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIP 1090 Query: 208 --KGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-PAGQL 264 G PG+ G G G PG G G+KGD G+ G G PG G+ G PG PGP PAGQ Sbjct: 1091 GMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQK 1150 Query: 265 -------IMGPKGERGFPGPPGRCLCG-PTMNVNNPSYGESVYG--PSSPRVP 307 I G GE+G PG PGR G P + S GE + SP +P Sbjct: 1151 GEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIP 1203 Score = 169 bits (428), Expect = 5e-42 Identities = 109/275 (39%), Positives = 128/275 (46%), Gaps = 79/275 (28%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGR---PGRKGRPGPPGVPGM-------- 132 + G G PG G G PG PG TGP G+KGE G PG G G PG+PG Sbjct: 1122 LPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGA 1181 Query: 133 ---------------------------------PGPIGWPG--------PEGPRGEKGDL 151 PGP G PG EGP+G++G Sbjct: 1182 KGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQ 1241 Query: 152 GMMGLPGSRGPMGSKGYPGSRGEKGSRGE------KGDLGPKGEKGFPGFPGMLGQKGEM 205 G GLPG GPMG G PG G KG +G G GPKG+ GF G PG+ G G Sbjct: 1242 GQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGIT 1301 Query: 206 GPKGE---PGIAGHRGPTGRPGKRGKQGQKGDSGV------MGPPGKPGP----SGQPGR 252 G KG+ PG+ G +GP G PG +G +G +GD GV GPPG PGP G+PG Sbjct: 1302 GSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGL 1361 Query: 253 PGPPGPPPAGQL--IMGPKGER------GFPGPPG 279 PGP GPP L + GPKG++ G PGPPG Sbjct: 1362 PGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPG 1396 Score = 167 bits (423), Expect = 2e-41 Identities = 105/226 (46%), Positives = 119/226 (52%), Gaps = 25/226 (11%) Query: 78 TSQSPCMQGSLGSPGPPGPQGPP--GLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP 135 T P G G+PG G +G P GLPG G G G G PG KG G PGVPG G Sbjct: 712 TPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGA 771 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP---KGEKGF 192 IG PG +G RGE G G+ G GS G G G PG+RG G +G G GP KGEKGF Sbjct: 772 IGPPGLQGIRGEPGPPGLPGSVGSPGVPGI-GPPGARGPPGGQGPPGLSGPPGIKGEKGF 830 Query: 193 PGFPG--MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGK------QGQKGDSGVMGPPGKP 244 PGFPG M G KG+ G +G PGI G G G PG++G G KG+ GVMG PG+P Sbjct: 831 PGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQP 890 Query: 245 GPSGQPGRPGPPGP-----------PPAGQLIMGPKGERGFPGPPG 279 G G G PG PG P + G KG+ G PG PG Sbjct: 891 GSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPG 936 Score = 167 bits (423), Expect = 2e-41 Identities = 101/215 (46%), Positives = 115/215 (53%), Gaps = 17/215 (7%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPG---------RKGRPGPPGVPG 131 SP G GSPG PG +G GLPG G G KGE G PG +KG PG G+PG Sbjct: 1101 SPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPG 1160 Query: 132 MPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKG 191 G G PG G RG G G G GS+G +G G GS G GS+GE+G +GP G +G Sbjct: 1161 SAGEKGEPGLPG-RGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQG 1219 Query: 192 FPGFPGMLGQ-----KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGP 246 PG PG G KG+ GP+G+PG+ G GP G PG G G KGD G G PG PG Sbjct: 1220 QPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGV 1279 Query: 247 SGQPGRPGPPGPPPAGQL--IMGPKGERGFPGPPG 279 G G PG G P G I G KG+ G PG PG Sbjct: 1280 PGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPG 1314 Score = 167 bits (422), Expect = 2e-41 Identities = 96/200 (48%), Positives = 109/200 (54%), Gaps = 25/200 (12%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 QG G PG PGP GPPGLPG G KG+KG G PG G PGP G PG G G G G Sbjct: 1241 QGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGI 1300 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRG---EKGDLGP----------KGEKG 191 G KGD+G G+PG +GP G G G +G++G +G KG GP KGE G Sbjct: 1301 TGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPG 1360 Query: 192 FPGF---PGMLGQKGEMGPKGEPGIAGH---RGPTGRPGKRGKQGQKGDSGVMGP----- 240 PG PG+ G +G GPKG+ G+ G GP G PG G GQKG+ G GP Sbjct: 1361 LPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRG 1420 Query: 241 -PGKPGPSGQPGRPGPPGPP 259 PG PGP G PG GPPG P Sbjct: 1421 FPGPPGPDGLPGSMGPPGTP 1440 Score = 166 bits (421), Expect = 3e-41 Identities = 105/238 (44%), Positives = 116/238 (48%), Gaps = 43/238 (18%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGR---KGRPGP---PGVPGMPGPIGW 138 QG G G GP GPPG+ TGP GEKGE G PG +G PGP PG+PG PGP G Sbjct: 316 QGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGL 375 Query: 139 PGP--------EGPRGEKGDLGMMG--LPGSRGPMGSKGYPGSRGEKGSRG--------- 179 P P G RGEKGD G G LPG G G G PGS G G G Sbjct: 376 PVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQ 435 Query: 180 --EKGDLGPKGEKGFPGFPGMLGQKGEMG----------------PKGEPGIAGHRGPTG 221 GD GP G G PGF G +G+KG+ G P+G PG G G G Sbjct: 436 PGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPG 495 Query: 222 RPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G RG G+ G +GV GP G PG GQPG G PG + G KG+ GFPG PG Sbjct: 496 AKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPG 553 Score = 157 bits (397), Expect = 2e-38 Identities = 95/211 (45%), Positives = 110/211 (52%), Gaps = 23/211 (10%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGM------PGP 135 P G G G PG G PGLPG PKG G +G G +G PG G PG PGP Sbjct: 549 PGQPGMTGRAGSPGRDGHPGLPG---PKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGP 605 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKG-------YPGSRGEKGSRGEKGDLGPKG 188 G+ GP GP G+KG G G PGS G G KG PG G +G G G GP+G Sbjct: 606 PGY-GPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQG 664 Query: 189 EKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSG 248 ++GFPG PG G GE G G+PGI G G PG +G G GD G G PG+PG +G Sbjct: 665 DRGFPGTPGRPGLPGEKGAVGQPGI----GFPGPPGPKGVDGLPGDMGPPGTPGRPGFNG 720 Query: 249 QPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 PG PG G G+ +G G +G PG PG Sbjct: 721 LPGNPGVQG--QKGEPGVGLPGLKGLPGLPG 749 Score = 157 bits (396), Expect = 2e-38 Identities = 89/186 (47%), Positives = 104/186 (55%), Gaps = 26/186 (13%) Query: 107 GPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLP---GSRGPM 163 G KG+KGE G PG +G G PGM GP GP+GP G+KGD G GLP G+RGP Sbjct: 43 GVKGQKGERGLPGLQG---VIGFPGMQGP---EGPQGPPGQKGDTGEPGLPGTKGTRGPP 96 Query: 164 GSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRP 223 G+ GYPG+ G G G+ GP G G PG G G++G +GP G PG AG+ GP G P Sbjct: 97 GASGYPGNPGLPGIPGQD---GPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLP 153 Query: 224 GKRGKQGQ----------KGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERG 273 G +G G+ KG+ G G PG PGP G PG GP GPP GP G G Sbjct: 154 GMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPG----FTGPPGPPG 209 Query: 274 FPGPPG 279 PGPPG Sbjct: 210 PPGPPG 215 Score = 130 bits (328), Expect = 2e-30 Identities = 67/139 (48%), Positives = 79/139 (56%), Gaps = 10/139 (7%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPG----------MPG 134 +G +G PG PG QGP GLPG G KG++G+ G PG KG PGPPG PG +PG Sbjct: 1304 KGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPG 1363 Query: 135 PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPG 194 P G PG +G +G G G G+ G G G G PG G G +GE G GP G +GFPG Sbjct: 1364 PEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPG 1423 Query: 195 FPGMLGQKGEMGPKGEPGI 213 PG G G MGP G P + Sbjct: 1424 PPGPDGLPGSMGPPGTPSV 1442 Score = 99.8 bits (247), Expect = 5e-21 Identities = 58/144 (40%), Positives = 75/144 (52%), Gaps = 11/144 (7%) Query: 54 PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGP----QGPPGLPGKTGPK 109 PP G + P P ++ + + P +G G PGPPGP +G PGLPG GP Sbjct: 1309 PPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPP 1368 Query: 110 GEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYP 169 G KG G PG KG+ G G+ G+PGP G PG +G G+KG++ G GP G +G+P Sbjct: 1369 GLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEM------GPAGPTGPRGFP 1422 Query: 170 GSRGEKGSRGEKGDLG-PKGEKGF 192 G G G G G G P + GF Sbjct: 1423 GPPGPDGLPGSMGPPGTPSVDHGF 1446 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/116 (33%), Positives = 47/116 (40%), Gaps = 17/116 (14%) Query: 31 DQKKRGGHKACCLLTPPPPP-----LFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQ 85 DQ +G A L PP PP + P G P P +K L + Sbjct: 1330 DQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGP---PGLKGLQGLPGPKGQQGVT 1386 Query: 86 GSLGSPGPPGPQGPPGLPGK---------TGPKGEKGELGRPGRKGRPGPPGVPGM 132 G +G PGPPG G G PG+ TGP+G G G G G GPPG P + Sbjct: 1387 GLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSV 1442 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 192 bits (487), Expect = 7e-49 Identities = 106/215 (49%), Positives = 124/215 (57%), Gaps = 20/215 (9%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPG--MPGPIGWP 139 P + G G G PG G PGLPG PKGE G G PG +G PGPPG PG + GP G P Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLPG---PKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP 1254 Query: 140 GPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE---------KGDLGPKGEK 190 GP+GP G G G GLPG GP G G G +GEKG+ G+ KGD GP G + Sbjct: 1255 GPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQ 1314 Query: 191 GFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQ- 249 G PG PG+ G KG+ G G PG G +GP+G PG G +G+ G G GPPG PGPSGQ Sbjct: 1315 GNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQS 1374 Query: 250 ---PGRPGPPGPP--PAGQLIMGPKGERGFPGPPG 279 G GPPG P P + + GP+G +G PGP G Sbjct: 1375 IIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1409 Score = 191 bits (486), Expect = 9e-49 Identities = 110/229 (48%), Positives = 126/229 (55%), Gaps = 36/229 (15%) Query: 87 SLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGV---PGMPGPIGWPGPEG 143 S+G PG PGP+G PGLPG G G KG +G PG G PG PG PG+PG G PGP G Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGS---RGEKGSRGEKGDLGPKGEKGF-------- 192 P+G G G GLPG GP+G G+PG GEKG G+ G GP G+KG Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191 Query: 193 ---PGFPGMLGQKGE------------MGPKGEPGIAGH---RGPTGRPGKRGK--QGQK 232 PG PG+ GQKG+ GPKGEPG G +GP G PG G +G K Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 233 GDSGVMGPPGKPGPSGQPGRPGPPGPP--PAGQLIMGPKGERGFPGPPG 279 G+ G GPPG+PGP+G G PGP GPP P I G KG G PG PG Sbjct: 1252 GNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPG 1300 Score = 186 bits (472), Expect = 4e-47 Identities = 109/225 (48%), Positives = 125/225 (55%), Gaps = 30/225 (13%) Query: 85 QGSLGSPGPPGPQGPPG------LPGKTGPKGEKGELGRPGRKGRPGPPGVPGMP---GP 135 +G LGSPG PG G PG LPG GPKGE G + G +G PG PG+PG+P GP Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 136 IGWP--GPEGPRGEKGDLGMMGLPGSRGPMGSKG-------YPGSRGEKGSRGEKGDLGP 186 +G P GP GP GEKG G+ G PG G G KG PG G G+ G GD+G Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679 Query: 187 KGEKGFPGFPGMLGQKGEMGPKGEPGIA--------GHRGPTGRPGKRGKQGQKGDSGVM 238 G+ G PG PG+ G G G G PGI G G G PG G G+ G G Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739 Query: 239 GPPGKPGPSGQPG--RPGPPGPP--PAGQLIMGPKGERGFPGPPG 279 GPPG PGP G+PG PGPPGPP P + +GPKG+RGFPGPPG Sbjct: 740 GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784 Score = 182 bits (461), Expect = 7e-46 Identities = 115/265 (43%), Positives = 128/265 (48%), Gaps = 31/265 (11%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 PP PP P P+ P + + E P L PGPPG +G PG+PG Sbjct: 823 PPGPPGIP--------GPIGQPGLHGIPGEKGDPGPP----GLDVPGPPGERGSPGIPGA 870 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGS 165 GP G G G PG+ G G PG G G +G PGP GP G G G+ GL G G G Sbjct: 871 PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQ 930 Query: 166 KGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGK 225 G PG GEKGS+GE G GP G P P +LG KGE G G PGI G GP G G Sbjct: 931 PGLPGPTGEKGSKGEPGLPGPPG----PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGL 986 Query: 226 RGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG--PPPAGQLIMGPKGERGFPGPPGRCLC 283 G GQ G SG G PG PGP G PG PG PG PP + G G+ GFPGP G Sbjct: 987 PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG---LKGTIGDMGFPGPQG---- 1039 Query: 284 GPTMNVNNPSYGESVYG-PSSPRVP 307 V P V G P SP +P Sbjct: 1040 -----VEGPPGPSGVPGQPGSPGLP 1059 Score = 181 bits (460), Expect = 9e-46 Identities = 110/249 (44%), Positives = 130/249 (52%), Gaps = 26/249 (10%) Query: 84 MQGSLGSPGPPGPQGP----------PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMP 133 +QG G+PG PG GP PG PG G G G++G PG G PG PG+PG+P Sbjct: 636 IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695 Query: 134 GP--------IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL- 184 G IG PGP GP+G G G G PG+ G +G +G PG G G +GE G Sbjct: 696 GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755 Query: 185 -GPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 GP G G PGF G LG KG+ G G PG G G G PG +G G G G MGPPG Sbjct: 756 PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815 Query: 244 PGPSGQPGRPGPPG-PPPAGQL-IMGPKGERGFPGPPGRCLCGPTMNVNNPSYGES---V 298 PG G G PGPPG P P GQ + G GE+G PGPPG + GP +P + + Sbjct: 816 PG-IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI 874 Query: 299 YGPSSPRVP 307 P SP +P Sbjct: 875 GPPGSPGLP 883 Score = 181 bits (460), Expect = 9e-46 Identities = 111/246 (45%), Positives = 130/246 (52%), Gaps = 22/246 (8%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 PP PP FP P G + P L P +G+LG G G GPPG PG+ Sbjct: 738 PPGPPGFPGPKGEPGFALPGPPGPPGL---------PGFKGALGPKGDRGFPGPPGPPGR 788 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDL---GMMGLPGSRGP 162 TG G G G G G+PGP G PG+PG IG GP GP G G + G+ G+PG +G Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQPGLHGIPGEKGD 847 Query: 163 MGSKG--YPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPT 220 G G PG GE+GS G G GP G G PG PG G G G KGE G+ G GP Sbjct: 848 PGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907 Query: 221 GR---PGKRGKQGQKGDSGVMGPPGKPGPSGQ---PGRPGPPGPP-PAGQLIMGPKGERG 273 G PG+ G G KGD G+ G PG PGP+G+ G PG PGPP P ++G KGE+G Sbjct: 908 GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG 967 Query: 274 FPGPPG 279 PG PG Sbjct: 968 EPGLPG 973 Score = 179 bits (453), Expect = 6e-45 Identities = 109/252 (43%), Positives = 128/252 (50%), Gaps = 51/252 (20%) Query: 85 QGSLGSPGPPGPQGP--------------PGLPGKTGPKGEKG---ELGRPGRKGR---P 124 +G G PGPPGP P PG+PG +GPKG +G + G+PG G+ P Sbjct: 943 KGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLP 1002 Query: 125 GPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSR------GPMGSKGYPGSRGEKGSR 178 GPPG G PG G PG GP G KG +G MG PG + GP G G PGS G G + Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062 Query: 179 GEKGD-----------LGPKGEKGFPGFPGMLGQKGEMGPKGEPGI---AGHRGPTGRPG 224 G+KGD GPKGE G PG+PG G KG +G G PG+ G +G G PG Sbjct: 1063 GDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG 1122 Query: 225 KRGKQGQKGDSGVMGPPGKPGPSGQP------GRPGPPGPP-----PAGQLIMGPKGERG 273 G G G G+ GPPG PG G+P G PG PGPP P I GP G++G Sbjct: 1123 FPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKG 1182 Query: 274 FPGPPGRCLCGP 285 PG PG GP Sbjct: 1183 EPGQPGFGNPGP 1194 Score = 178 bits (451), Expect = 1e-44 Identities = 125/333 (37%), Positives = 154/333 (46%), Gaps = 77/333 (23%) Query: 15 SGLLCYSAGCLALPSLDQKK--RG-----------GHKACCLLTPPPPPLFPPPFFRGGR 61 +G+ G + LP L +K RG G ++ PP PP FP RG + Sbjct: 351 TGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGE--RGQK 408 Query: 62 SPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGP----------------PGLPGK 105 P + P + G G+PG PGP GP PG PG Sbjct: 409 GDEGPPG-------ISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGS 461 Query: 106 TGPKGEKGELGRPGRKG----------------RPGPPGVPGMPGPIGWPGPEGPRGEKG 149 G KG +GE G G KG +PG PG+PG PG +G+PG +G +G+ G Sbjct: 462 PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521 Query: 150 DLGMMGLPGSRGPMGSKGYPGSRGEKGS-------RGEKGDLGPKGEKGFPGFPGMLGQ- 201 G GLPG G G+ G+PGS+GE G +G+KG+LG G G PG PG GQ Sbjct: 522 ATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQD 581 Query: 202 --KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPP--GKPGP---------SG 248 G GPKGEPG +G G PG G G G+ G MGPP G PGP +G Sbjct: 582 GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641 Query: 249 QPGRPGPPGPP-PAGQLIMGPKGERGFPGPPGR 280 PG+PG PGP GQ I P G+ G PG PGR Sbjct: 642 NPGQPGIPGPKGDPGQTITQP-GKPGLPGNPGR 673 Score = 177 bits (450), Expect = 1e-44 Identities = 108/259 (41%), Positives = 127/259 (49%), Gaps = 46/259 (17%) Query: 60 GRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTG------PKGEKG 113 G SP D + E P ++G G PG PGP+GPPG G+ G P G KG Sbjct: 31 GCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKG 90 Query: 114 ELGRPGRKGRPGPPGVPGMPGPIGWPGPE------GPRGEKGDLGMMGLPGSRGPMGSKG 167 G PG G PG PG+PGMPG G PGP+ G +GE+G G G PG +GP G G Sbjct: 91 IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Query: 168 YPGSRGEKGS------RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTG 221 PG +GE GS G KG+ G G G G PG G G +GP G PG+ G GP G Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 222 RPGKRGK--------QGQKGDSGVMGPPGKPG-------------PSGQPGRPGPPGPPP 260 PG +G +G+KG+ G+ GPPG PG G G PG GPP Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPP- 269 Query: 261 AGQLIMGPKGERGFPGPPG 279 GP G RG PGPPG Sbjct: 270 ------GPPGIRGPPGPPG 282 Score = 177 bits (448), Expect = 2e-44 Identities = 124/345 (35%), Positives = 144/345 (41%), Gaps = 83/345 (24%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGP------------ 93 P P L P G P P E SP G G PGP Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160 Query: 94 ------PGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP------ 141 PGP+G PG PG G +G G G PG G PGPPG+ G PGP G PGP Sbjct: 161 IIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGL 220 Query: 142 --EGPRGEKGDLGMMGLPGSRGPM-------------GSKGYPGSRGEKGSRGEKGDLGP 186 +GP+GEKG+ G+ G PG G + G +G PG RG G G +G GP Sbjct: 221 NFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP 280 Query: 187 ----KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPG 242 KGEKG G PG G+ G+ G G+PGI G G G PG+ G+ G+KG G GPPG Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340 Query: 243 KP----------------------------GPSGQPGRPGPPG-PPPAGQLIMGPKGERG 273 P G G PG GPPG P P G +MGP G G Sbjct: 341 PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG 400 Query: 274 FP---------GPPGRCLCGPTMNVNNPSYG--ESVYGPSSPRVP 307 FP GPPG + GP P GP+ P +P Sbjct: 401 FPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445 Score = 172 bits (436), Expect = 6e-43 Identities = 112/264 (42%), Positives = 138/264 (52%), Gaps = 35/264 (13%) Query: 43 LLTPPPPPLFPPPF------FRG--------------GRSPLLSPDMKNLMLELETSQSP 82 L+ PP PP P P F+G G +S + + +E + Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 83 CMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGP------PGVPGMPGPI 136 + G G PGPPG +GPPG PG G KGEKGE G PG++G+PG PG+PG+PG Sbjct: 262 -LPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 G+PG G GEKG G G PG G + + PG+ G +G G G GEKG GFP Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPR--PGTGITIGEKGNIGLPGLPGEKGERGFP 376 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 G+ G G GP G + G GP G PG+RG++G +G G+ PG PG GQPG PG P Sbjct: 377 GIQGPPGLPGPPGA-AVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPGAPGLP 434 Query: 257 GPP-PAGQLIMGPKGERGFPGPPG 279 GPP PAG I P E PGPPG Sbjct: 435 GPPGPAGPHI-PPSDEICEPGPPG 457 Score = 170 bits (430), Expect = 3e-42 Identities = 101/229 (44%), Positives = 114/229 (49%), Gaps = 38/229 (16%) Query: 79 SQSPCMQGSLGSPGPPGP---------------QGPPGLPGKTGPKGEKGELGRPGRKGR 123 S P ++G G+PGP GP +GPPGLPG G KGEKG G+PG G Sbjct: 1242 SPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1301 Query: 124 PGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD 183 PG G G PG G PG G G KGD G+ G+PG G G G PGS G +G G G Sbjct: 1302 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1361 Query: 184 LGP-------------KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQG 230 GP KG+ G PG PG G KG GP+G G+ G GP G PG+ G G Sbjct: 1362 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1421 Query: 231 QKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G G G PG P GQPG G GPP GP G +G PGPPG Sbjct: 1422 FDGAGGRKGDPGLP---GQPGTRGLDGPP-------GPDGLQGPPGPPG 1460 Score = 169 bits (428), Expect = 5e-42 Identities = 116/302 (38%), Positives = 137/302 (45%), Gaps = 85/302 (28%) Query: 82 PCMQGSLGSPGPPG-----PQGPPGLPGKTGPKGEKGELG-----------RPGRKG--- 122 P +QG G PGPPG P GPPG PG+ G KG++G G +PG G Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435 Query: 123 ----------------RPGPPGVPGMPGPIGWPGPEGPRGEKGDL-------------GM 153 PGPPG PG PG G G +G +G+KGD G Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 154 MGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL------GPKGEKGFPG----------FPG 197 GLPG GP GS G+PG +GEKG G G G G GFPG FPG Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555 Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGD------SGVMGPPGKPGPSGQPG 251 M G KGE+G G PG+ G G G+ G G G KG+ G GPPG PG G PG Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615 Query: 252 RPGPPGPPPAGQLIMGPKGERGF------PGPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 GP GPP G GP GE+G PG PG + GP +P G+++ P P Sbjct: 616 NIGPMGPPGFGP--PGPVGEKGIQGVAGNPGQPG--IPGPK---GDP--GQTITQPGKPG 666 Query: 306 VP 307 +P Sbjct: 667 LP 668 Score = 168 bits (426), Expect = 8e-42 Identities = 104/250 (41%), Positives = 118/250 (47%), Gaps = 46/250 (18%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGP------PGPQGP 99 PP PP P P G + +P QG G PGP PGP+GP Sbjct: 1236 PPGPPGSPGPALEGPKG------------------NPGPQGPPGRPGPTGFQGLPGPEGP 1277 Query: 100 PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGS 159 PGLPG G KGEKG G+PG G PG G G PG G PG G G KGD G+ G+PG Sbjct: 1278 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1337 Query: 160 RGPMGSKGYPGSRGEKGSRGEKGDLGP-------------KGEKGFPGFPGMLGQKGEMG 206 G G G PGS G +G G G GP KG+ G PG PG G KG G Sbjct: 1338 PGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1397 Query: 207 PKGEPGIAGHRGPTGRPGKRGKQG------QKGDSGVMGPPGK---PGPSGQPGRPGPPG 257 P+G G+ G GP G PG+ G G +KGD G+ G PG GP G G GPPG Sbjct: 1398 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1457 Query: 258 PPPAGQLIMG 267 PP + G Sbjct: 1458 PPGTSSVAHG 1467 Score = 166 bits (419), Expect = 5e-41 Identities = 112/290 (38%), Positives = 128/290 (44%), Gaps = 69/290 (23%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIG------ 137 + G G PG PG GPPG G G KGEKG+ G G KG PG PG PG PG G Sbjct: 489 ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG 548 Query: 138 ----WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE---KGDLGPKGEK 190 +PG +G +GE G G GLPG G G G PG G KG G KG+ GP G Sbjct: 549 DILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNP 608 Query: 191 GFPGFPGML--------------------------GQKGEMGPKGEP------------- 211 G PG PG + GQ G GPKG+P Sbjct: 609 GLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLP 668 Query: 212 ---------GIAGHRGPTGRPGKRGKQGQKGDSGV--MGPPGKPGPSGQPGRPGPPGPP- 259 G+ G G G+PG G G KG+ G+ +G PG PGP G PG PGPPG P Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728 Query: 260 -PAGQLIMGPKGERGFPGP---PGRCLCGPTMNVNNPSYGESVYGPSSPR 305 P + GP G GFPGP PG L GP P + + GP R Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF-KGALGPKGDR 777 Score = 165 bits (417), Expect = 9e-41 Identities = 94/207 (45%), Positives = 113/207 (54%), Gaps = 16/207 (7%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEG 143 ++G G G PG +G PGLPG GP+G PG +G+ G G+PG PGP G GP G Sbjct: 43 IKGEKGERGFPGLEGHPGLPGFPGPEGP------PGPRGQKGDDGIPGPPGPKGIRGPPG 96 Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKG 203 G G G+ G+PG G G +G PG G KG RG G G G +G PG PG+ G KG Sbjct: 97 LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156 Query: 204 EMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG-PPPAG 262 E G + G +G G PG G QG G +G+ GP G PGP G G PGPPG P P G Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216 Query: 263 QL---IMGPKGERGF------PGPPGR 280 + GPKGE+G PGPPG+ Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQ 243 Score = 84.3 bits (207), Expect = 2e-16 Identities = 50/116 (43%), Positives = 59/116 (50%), Gaps = 16/116 (13%) Query: 43 LLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGL 102 L+ PP PP P P G+S ++ D + P + G G G PGPQGP GL Sbjct: 1358 LIGPPGPPGLPGP---SGQSIIIKGD----------AGPPGIPGQPGLKGLPGPQGPQGL 1404 Query: 103 PGKTGPKGEKGELGRP---GRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMG 155 PG TGP G+ G G P G GR G PG+PG PG G GP GP G +G G G Sbjct: 1405 PGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 191 bits (485), Expect = 1e-48 Identities = 107/235 (45%), Positives = 125/235 (53%), Gaps = 14/235 (5%) Query: 59 GGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRP 118 G PL M L +P +G+ G PG PGP GP G+PG +G G G G Sbjct: 330 GAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEA 389 Query: 119 GRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGY---PGSRGEK 175 G G GP G G G G PGP G G G +G G PG++GP GS G PGS G Sbjct: 390 GPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPP 449 Query: 176 GSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDS 235 GS G +G GP+G +G PG PG+ G KGE GPKGEPG G +GP G PG+ GK+G +GD Sbjct: 450 GSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDP 509 Query: 236 GVMGPPGKPGPSGQPGRPGPPG----PPPAGQL-------IMGPKGERGFPGPPG 279 G +GPPG G G PG G PG P P G GPKG +G PG PG Sbjct: 510 GTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPG 564 Score = 189 bits (479), Expect = 6e-48 Identities = 93/198 (46%), Positives = 110/198 (55%), Gaps = 7/198 (3%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P G +G PGP GP G G PG+ G GE+G+ G PG G PG G PG PGP+G PG Sbjct: 1037 PGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGD 1096 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 G RG+ G G +G PG G G G G RG+KG G++GD G KG +GF G G+ G Sbjct: 1097 AGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGP 1156 Query: 202 KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPA 261 G G +G GI G GP G PG G G++G+ G +GP G PG G G GP GPP Sbjct: 1157 PGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPP-- 1214 Query: 262 GQLIMGPKGERGFPGPPG 279 G G G PGPPG Sbjct: 1215 -----GEPGPPGPPGPPG 1227 Score = 188 bits (477), Expect = 1e-47 Identities = 97/204 (47%), Positives = 114/204 (55%), Gaps = 5/204 (2%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGR---PGPPGVPGMPGPIG 137 SP QG GSPGP GP G PGL G G +G G G PG GR PGP G PG GP+G Sbjct: 874 SPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLG 933 Query: 138 WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPG 197 PG EGP G +GD G G G RGP G G PG +G+ G G+ G GP G G G G Sbjct: 934 EPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRG 993 Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG 257 ++G G+ G +G PG+ G G G+ G G G KG G +GPPG GP G+PG GP G Sbjct: 994 IVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAG 1053 Query: 258 --PPPAGQLIMGPKGERGFPGPPG 279 P +G +G+RG PGP G Sbjct: 1054 NDGTPGRDGAVGERGDRGDPGPAG 1077 Score = 181 bits (460), Expect = 9e-46 Identities = 101/222 (45%), Positives = 115/222 (51%), Gaps = 30/222 (13%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGM------------- 132 GS G GPPG G G PG+ G GE G G PG +G PG PG+PG+ Sbjct: 252 GSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPK 311 Query: 133 -----PGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP- 186 PG G GP GP G G LG G+PG RG +G +G PG RG G G+ G +GP Sbjct: 312 GEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL 371 Query: 187 --KGEKGFPGFPGMLGQ------KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVM 238 G GFPG PGM G+ +G GP+G+ G G GP G PG G G G G Sbjct: 372 GIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAK 431 Query: 239 GPPGKPGPSGQPGRPGPPGPP-PAGQLIMGPKGERGFPGPPG 279 GP G PG SG PG GPPG P P G GP+G RG PG PG Sbjct: 432 GPTGSPGTSGPPGSAGPPGSPGPQGS--TGPQGIRGQPGDPG 471 Score = 181 bits (459), Expect = 1e-45 Identities = 99/202 (49%), Positives = 112/202 (55%), Gaps = 7/202 (3%) Query: 81 SPCMQGSLGSPGPPGPQGPPG---LPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIG 137 SP G+ G GPPG QG PG + G GPKG++G +G G +G G G G+PGP+G Sbjct: 745 SPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLG 804 Query: 138 WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPG 197 PGP GP GEKG+ G GL GP GS+G PGSRGE G G G GP+G G PG G Sbjct: 805 PPGPAGPTGEKGEPGPRGLV---GPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKG 861 Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG 257 G+ G+ G G PG G G G G G G KG G GPPG G G GR GPPG Sbjct: 862 EPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG 921 Query: 258 PPPAGQLIMGPKGERGFPGPPG 279 P A GP GE G GPPG Sbjct: 922 PAGAPG-PAGPLGEPGKEGPPG 942 Score = 181 bits (458), Expect = 2e-45 Identities = 97/203 (47%), Positives = 112/203 (55%), Gaps = 8/203 (3%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGE---KGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 QG G GPPGP G PGLPG G G KG G PG G PG G PG PGP G GP Sbjct: 401 QGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGP 460 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 +G RG+ GD G+ G G GP G G G +G G GE+G GP+G+ G G PG +G+ Sbjct: 461 QGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGE 520 Query: 202 KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-- 259 +G G +G PG G GP G G+RG G G G G PG+PG G PG G G P Sbjct: 521 RGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGV 580 Query: 260 --PAGQL-IMGPKGERGFPGPPG 279 P G+L +G GE G PGPPG Sbjct: 581 QGPEGKLGPLGAPGEDGRPGPPG 603 Score = 176 bits (447), Expect = 3e-44 Identities = 107/240 (44%), Positives = 122/240 (50%), Gaps = 9/240 (3%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELET-SQSPCMQGSLGSPGPPGPQGPPGLPG 104 PP P P P G S S M L + SQ M GS+G GP GPQG G G Sbjct: 175 PPGHPSHPGP---DGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQG 231 Query: 105 KTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMG 164 GP G GE G PG G G G G PG G G G G G++G G PG+RG G Sbjct: 232 GAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPG 291 Query: 165 SKGYPG---SRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTG 221 + G PG RG KG G KG++G G KG G G +G G +GP+G PG G GP G Sbjct: 292 APGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQG 351 Query: 222 RPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 PG+RG G G G MGP G PG SG PG PG G P + GP+G+RG GPPG Sbjct: 352 APGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPG 411 Score = 176 bits (447), Expect = 3e-44 Identities = 101/230 (43%), Positives = 120/230 (52%), Gaps = 35/230 (15%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G +G PG G +G PGLPG G G+ G G G KG PGP G PG GP+G PGPEGP Sbjct: 992 RGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGP 1051 Query: 145 ---------------RGEKGDLGMMGLPGSRG------PMGSKGYPGSRGEKGSRGEKGD 183 RG++GD G GLPGS+G P+G+ G G RG+ GSRG G Sbjct: 1052 AGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGP 1111 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 G G++G PG G G KG+ G +G+ G GHRG TG G G G G+ G G PG Sbjct: 1112 PGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGP 1171 Query: 244 PGPSGQPGRPGPPG----PPPAGQL----------IMGPKGERGFPGPPG 279 GP G PG GP G P P G + GP+G G PGPPG Sbjct: 1172 FGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPG 1221 Score = 175 bits (443), Expect = 9e-44 Identities = 101/231 (43%), Positives = 122/231 (52%), Gaps = 26/231 (11%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMP------GPIG 137 +QG +G PG G +GP G PG GP G GE G PG +G PG G+PG GP+G Sbjct: 490 IQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVG 549 Query: 138 WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGE---KGSRGEKGDLGPKGEKGFPG 194 GP+G +G+ G G GLPG+RG G+ G G G+ G+ GE G GP G G G Sbjct: 550 SSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRG 609 Query: 195 FPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKR---GKQGQKGDSGVMGPP---------G 242 PG +G G G G+PG G G G PG+R GK G+ G SG +GPP G Sbjct: 610 QPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQG 669 Query: 243 KPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRC-LCGPTMNVNNP 292 PGP+G G PGPPGPP G G G++G PG PG GP NP Sbjct: 670 PPGPTGFQGLPGPPGPPGEG----GKPGDQGVPGDPGAVGPLGPRGERGNP 716 Score = 175 bits (443), Expect = 9e-44 Identities = 98/216 (45%), Positives = 111/216 (51%), Gaps = 25/216 (11%) Query: 82 PCMQGSLGSPGPPGP---------QGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGM 132 P G G PGPPGP QG PG PG GP G +GE G PG +G PG G+PG Sbjct: 671 PGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGE 730 Query: 133 PGPIGWPGPEGPRGEKG------DLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP 186 G G GP+GP+G G D G GL G G G G PG +G++G GEKG G Sbjct: 731 KGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGT 790 Query: 187 KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSG---VMGPPGK 243 G G G PG LG G GP GE G G RG G PG RG G +G++G +G G Sbjct: 791 AGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGP 850 Query: 244 PGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 GP GQPG G PG P G KG+ G PGP G Sbjct: 851 QGPDGQPGVKGEPGEP-------GQKGDAGSPGPQG 879 Score = 174 bits (441), Expect = 1e-43 Identities = 108/263 (41%), Positives = 129/263 (49%), Gaps = 11/263 (4%) Query: 45 TPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 T PP P+ P G +P K TS P G GSPGP G GP G+ G Sbjct: 407 TGPPGPVGSPGL-PGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRG 465 Query: 105 KTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMG 164 + G G G G G KG PGP G+ GPIG PG EG RG +GD G +G P GP+G Sbjct: 466 QPGDPGVPGFKGEAGPKGEPGPHGI---QGPIGPPGEEGKRGPRGDPGTVGPP---GPVG 519 Query: 165 SKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPG 224 +G PG+RG GS G G G +GE+G G G G +G+ G GEPG+ G RG TG PG Sbjct: 520 ERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPG 579 Query: 225 KRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCG 284 +G +G+ G G G G+PGP G G G PG + GPKG G PG PG Sbjct: 580 VQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPG----SMGLPGPKGSSGDPGKPGEAGNA 635 Query: 285 PTMNVNNPSYGESVYGPSSPRVP 307 + GPS P P Sbjct: 636 GVPGQRGAPGKDGEVGPSGPVGP 658 Score = 172 bits (437), Expect = 4e-43 Identities = 100/228 (43%), Positives = 117/228 (51%), Gaps = 5/228 (2%) Query: 54 PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKG 113 PP G R P P + +P +G GS G PGP+G G G G G KG Sbjct: 496 PPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKG 555 Query: 114 ELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRG 173 G PGR G PG PG G+ G G GPEG G G G G PG G +G +G PGS G Sbjct: 556 SQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMG 615 Query: 174 EKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKG 233 G +G GD G GE G G P GQ+G G GE G +G GP G G+RG+QG G Sbjct: 616 LPGPKGSSGDPGKPGEAGNAGVP---GQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPG 672 Query: 234 DSGVMGPPGKPGPSGQPGRPGPPGPP--PAGQLIMGPKGERGFPGPPG 279 +G G PG PGP G+ G+PG G P P +GP+GERG PG G Sbjct: 673 PTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG 720 Score = 172 bits (437), Expect = 4e-43 Identities = 95/199 (47%), Positives = 109/199 (54%), Gaps = 9/199 (4%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVP---GMPGPIGWPGPE 142 G G+PGP GP G PG G G +G+ G GR G +G GPPG P G PG G PGP+ Sbjct: 921 GPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPD 980 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK 202 GP G G G G+ G G G +G PG G G+ G+ +GP G G G PG +G Sbjct: 981 GPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK---VGPTGATGDKGPPGPVGPP 1037 Query: 203 GEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-PA 261 G GP GEPG G G G PG+ G G++GD G GP G PG G PG PGP G P A Sbjct: 1038 GSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDA 1097 Query: 262 GQLIMGPKGERGFPGPPGR 280 GQ G G RG GPPGR Sbjct: 1098 GQ--RGDPGSRGPIGPPGR 1114 Score = 171 bits (433), Expect = 1e-42 Identities = 111/280 (39%), Positives = 137/280 (48%), Gaps = 62/280 (22%) Query: 59 GGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPG---PPGPQGPPGLPG---KTGP---K 109 G P+ SP + + T +P +G GSPG PPG GPPG PG TGP + Sbjct: 408 GPPGPVGSPGLPGA---IGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIR 464 Query: 110 GEKGELGRPGRKGRPGPPGVPG---MPGPIGWPGPEGPRGEKGD---------LGMMGLP 157 G+ G+ G PG KG GP G PG + GPIG PG EG RG +GD +G G P Sbjct: 465 GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAP 524 Query: 158 GSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPG---------------MLGQK 202 G+RG GS G PG +G +G RG G GPKG +G PG PG + G + Sbjct: 525 GNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPE 584 Query: 203 GEMGP------------------KGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKP 244 G++GP +G+PG G GP G G GK G+ G++GV G G P Sbjct: 585 GKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAP 644 Query: 245 GPSGQPGRPGPPGPPPAG-----QLIMGPKGERGFPGPPG 279 G G+ G GP GPP Q GP G +G PGPPG Sbjct: 645 GKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPG 684 Score = 171 bits (433), Expect = 1e-42 Identities = 96/221 (43%), Positives = 116/221 (52%), Gaps = 34/221 (15%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPG---VPGMPGPIGWPGPE 142 G G PG PG +G G PG GP+G+ G LG PG GRPGPPG + G PG +G PGP+ Sbjct: 561 GRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPK 620 Query: 143 GPRGE---KGDLGMMGLPGSRGPMGSKGYPGSRGE------KGSRGEKGDLGPKGEKGFP 193 G G+ G+ G G+PG RG G G G G G RGE+G GP G +G P Sbjct: 621 GSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLP 680 Query: 194 GFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVM--------------- 238 G PG G+ G+ G +G PG G GP G G+RG G++G+ G+ Sbjct: 681 GPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPD 740 Query: 239 GPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 GP G PGPSG PG GPPG + G GERG G PG Sbjct: 741 GPKGSPGPSGTPGDTGPPG-------LQGMPGERGIAGTPG 774 Score = 171 bits (432), Expect = 2e-42 Identities = 95/217 (43%), Positives = 109/217 (50%), Gaps = 29/217 (13%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGR---------------------KGRP 124 G++G GP GP G PG+ G+ G G+KG+ G PG +G Sbjct: 843 GAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQ 902 Query: 125 GPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL 184 GPPG G PG G GP GP G G G +G PG GP G +G PGS G G RG G Sbjct: 903 GPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPP 962 Query: 185 GPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKP 244 G G+KG PG G Q G GP G G G RG G PG+RG++G G G G PGK Sbjct: 963 GGPGDKGDPGEDG---QPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKV 1019 Query: 245 GPSGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 GP+G G GPPGP PP GP GE G GP G Sbjct: 1020 GPTGATGDKGPPGPVGPPGSN---GPVGEPGPEGPAG 1053 Score = 170 bits (431), Expect = 2e-42 Identities = 102/232 (43%), Positives = 121/232 (52%), Gaps = 18/232 (7%) Query: 78 TSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIG 137 +S P G G+ G PG +G PG G+ GP G G G G +G GPPG G G G Sbjct: 622 SSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPG 681 Query: 138 WPGPEGPRGEKGDLGMMGLPGSRGPM---GSKGYPGSRGEKGSR---GEKGDLGPKGEKG 191 PGP G G+ GD G+ G PG+ GP+ G +G PG RGE G GEKG G G G Sbjct: 682 PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDG 741 Query: 192 FPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPG 251 G PG G G+ GP G G+ G RG G PG +G +G G+ G G G G G PG Sbjct: 742 PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPG 801 Query: 252 RPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNP-SYGESVYGPS 302 GPPGP GP GE+G PGP G L GP + NP S GE+ GP+ Sbjct: 802 PLGPPGP-------AGPTGEKGEPGPRG--LVGPPGSRGNPGSRGEN--GPT 842 Score = 170 bits (431), Expect = 2e-42 Identities = 110/291 (37%), Positives = 139/291 (47%), Gaps = 57/291 (19%) Query: 46 PPPPPLFPPPFFR-GGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 PP FP R G P +P + E P ++G GS G G +GP G PG Sbjct: 904 PPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPG 963 Query: 105 KTGPKGEKGELGRPGRKGRPGPPG------------------VPGMPGPIGWPG---PEG 143 G KG+ GE G+PG G PGP G +PG+PGP G PG P G Sbjct: 964 GPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG 1023 Query: 144 PRGEKGDLGMMGLPGSRGPM---------GSKGYPGSRGEKGSRGEKGDLGP---KGEKG 191 G+KG G +G PGS GP+ G+ G PG G G RG++GD GP G +G Sbjct: 1024 ATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQG 1083 Query: 192 FPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGK---------------------RGKQG 230 PG PG +G G+ G +G+PG G GP GR GK RG++G Sbjct: 1084 APGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKG 1143 Query: 231 QKGDSGVMGPPGKPGPSGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 +G +G+ G PG PGP+G+ G G PGP P +GP G+ G PGP G Sbjct: 1144 HRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLG 1194 Score = 169 bits (429), Expect = 4e-42 Identities = 110/279 (39%), Positives = 129/279 (46%), Gaps = 45/279 (16%) Query: 46 PPPPPLFPPPFFR-GGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 PP P P P G R P P E + +P G GSPG G G PGLPG Sbjct: 238 PPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPG 297 Query: 105 KTGPKGEKG------ELGRPGRKGRPGPPGVPGMPGPIG---WPGPEG---PRGEKGDLG 152 G +G KG E+G PG KG GP G G GP+G PG G P+G G G Sbjct: 298 LKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRG 357 Query: 153 MMGLPGSRGPMGSKGYPGS------------------RGEKGSRGEKGDLGPKGEKGFPG 194 G+PG GPMG G PGS RG +G +G++G+ GP G G PG Sbjct: 358 AHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPG 417 Query: 195 FPGMLGQKGE---MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKP------- 244 PG +G G GP G PG +G G G PG G QG G G+ G PG P Sbjct: 418 LPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKG 477 Query: 245 --GPSGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 GP G+PG G GP PP + GP+G+ G GPPG Sbjct: 478 EAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPG 516 Score = 168 bits (426), Expect = 8e-42 Identities = 96/225 (42%), Positives = 111/225 (49%), Gaps = 3/225 (1%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEG 143 +QG G GP GP G PG PG GP G +G G PG+ G G PG G PG +G+ G G Sbjct: 226 LQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPG 285 Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKG 203 RG G G+ GL G RG G +G G G GS+GE G GP G G G GM G++G Sbjct: 286 ARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERG 345 Query: 204 EMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQ 263 +GP+G PG G G G+PG G G G SG G PG G +G G GP G P GQ Sbjct: 346 RLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEG--PQGQ 403 Query: 264 L-IMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVP 307 GP G G PG PG T P+ GP P Sbjct: 404 RGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGP 448 Score = 166 bits (420), Expect = 4e-41 Identities = 94/232 (40%), Positives = 113/232 (48%), Gaps = 25/232 (10%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVP---------GM 132 P +G+ G G GP GP G PG G +GE+G G G +G PGPPG P G+ Sbjct: 638 PGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGV 697 Query: 133 PGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGF 192 PG G GP GPRGE+G+ G G PG G G KG G G G +G G G G+ G Sbjct: 698 PGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGP 757 Query: 193 PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 PG GM G++G G G G G G G G G G +G G +GPPG GP+G+ G Sbjct: 758 PGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGE 817 Query: 253 PGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 PGP G ++GP G RG PG G N P+ GP P Sbjct: 818 PGPRG-------LVGPPGSRGNPGSRGE---------NGPTGAVGFAGPQGP 853 Score = 162 bits (411), Expect = 4e-40 Identities = 98/220 (44%), Positives = 113/220 (51%), Gaps = 26/220 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG---------PI 136 GS G PGP G QG G G +GPKG +G+ GRPG G PG G+ G PG P+ Sbjct: 531 GSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPL 590 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRG---PMGSKGYPGSRGEKGS------RGEKGDLGPK 187 G PG +G G G +G+ G PGS G P GS G PG GE G+ RG G G Sbjct: 591 GAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEV 650 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGK---QGQKGDSGVMGPPGKP 244 G G G PG+ G++GE GP G G G GP G PG+ GK QG GD G +GP G Sbjct: 651 GPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPR 710 Query: 245 GPSGQPGRPGPPG----PPPAGQL-IMGPKGERGFPGPPG 279 G G PG G PG P G GP G +G PGP G Sbjct: 711 GERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSG 750 Score = 162 bits (410), Expect = 6e-40 Identities = 113/300 (37%), Positives = 127/300 (42%), Gaps = 81/300 (27%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWP-- 139 P + G G PGP GP G G G+ GPKG G G G G PG PG PG PGP G P Sbjct: 122 PVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSH 181 Query: 140 ----------------------------------GPEGPR------------------GE 147 GP GPR GE Sbjct: 182 PGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGE 241 Query: 148 KGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL---GPKGEKGFPGFPGMLGQKGE 204 GD G MG GSRGP G G PG GE G G G++ G G +GFPG PG+ G KG Sbjct: 242 PGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGH 301 Query: 205 M------GPKGE---PGIAGHRGPTGRP------GKRGKQGQKGDSGVMGPPGKPGPSGQ 249 GPKGE PG G GPTG G RG G++G G G PG+ G G Sbjct: 302 RGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGM 361 Query: 250 PGRPGPPGPPPAGQLIMGPKGERGFPGPPG-RCLCGPTMNVNNPSYGESVYGPSSPRVPV 308 PG+PGP GP +G G GFPG PG + GPT P + G + P PV Sbjct: 362 PGKPGPMGP-------LGIPGSSGFPGNPGMKGEAGPT-GARGPEGPQGQRGETGPPGPV 413 Score = 134 bits (338), Expect = 1e-31 Identities = 95/245 (38%), Positives = 115/245 (46%), Gaps = 32/245 (13%) Query: 79 SQSPCMQGSLGSPGPPGPQGPPGL-PGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIG 137 SQ+P + G G +G PGL P TG +G G G PG +G G G G Sbjct: 97 SQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGR----- 151 Query: 138 WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRG-------EKGSRGEKGDLGPKGEK 190 PGP GP+G G+ G+ G PG+ GP G +PG G + EK LG + Sbjct: 152 -PGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGL 210 Query: 191 GFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 PG G +G +G G +G+ G AG GP G PG G G G G GPPGKPG G+P Sbjct: 211 -MPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEP 269 Query: 251 GRPGPPGPPPAGQLIMGPKGERGFPGPPG----------RCLCGPTMNVNNP-SYGESVY 299 GR G PG G G RGFPG PG + L GP V P S GE+ Sbjct: 270 GRNGNPGEVG----FAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEA-- 323 Query: 300 GPSSP 304 GP+ P Sbjct: 324 GPTGP 328 Score = 113 bits (282), Expect = 4e-25 Identities = 65/150 (43%), Positives = 77/150 (51%), Gaps = 21/150 (14%) Query: 81 SPCMQGSLGSPGPPGPQGPP------GLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG 134 +P G G PG GP GPP GLPG GP+G+KG+ G G +G+ G G G+ Sbjct: 1093 APGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQ- 1151 Query: 135 PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPG 194 G PGP GP GE+G G+ GP G +G PG G G G G LGP G Sbjct: 1152 --GLPGPPGPNGEQGSAGI------PGPFGPRGPPGPVGPSGKEGNPGPLGPIGP----- 1198 Query: 195 FPGMLGQKGEMGPKGEPGIAGHRGPTGRPG 224 PG+ G GE GP+G PG G GP G PG Sbjct: 1199 -PGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227 Score = 89.4 bits (220), Expect = 6e-18 Identities = 65/175 (37%), Positives = 75/175 (42%), Gaps = 31/175 (17%) Query: 157 PGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGF-PGFPGMLGQKGEMGPKGEPGIAG 215 PG P+ S+ PG RG KG KGE G P G+ G+ G GP G G G Sbjct: 89 PGECCPVCSQT-PGGGNTNFGRGRKGQ---KGEPGLVPVVTGIRGRPGPAGPPGSQGPRG 144 Query: 216 HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG--PPPAGQLI-------- 265 RGP GRPG RG QG G+ GV G PG PGP G P PGP G P + Q+ Sbjct: 145 ERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGL 204 Query: 266 -------------MGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVP 307 +GP+G +G G G GPT P GP R P Sbjct: 205 GSQVGLMPGSVGPVGPRGPQGLQGQQGG--AGPTGPPGEPG-DPGPMGPIGSRGP 256 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 191 bits (484), Expect = 1e-48 Identities = 109/237 (45%), Positives = 128/237 (54%), Gaps = 25/237 (10%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 P P L P RG P P + + +P +G++G PG PGP G G G Sbjct: 598 PGPRGLLGP---RGSPGPTGRPGVTGI------DGAPGAKGNVGPPGEPGPPGQQGNHGS 648 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMP---GPIGWPGPEGPRGEKGDLGMMGLPGSRGP 162 G G +G +G PG KG PG PG+PG+P GP+G PG EGP GEK G G PGS GP Sbjct: 649 QGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK---GAQGPPGSAGP 705 Query: 163 MGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGR 222 GYPG RG KG+ G +G G KGEKG GFPG G G G +G+PG G RG G Sbjct: 706 ---PGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGP 762 Query: 223 PGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G +G+ GQ G+ G G G+ G G PG PG PG P GPKG GFPGP G Sbjct: 763 EGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRP-------GPKGSIGFPGPLG 812 Score = 189 bits (479), Expect = 6e-48 Identities = 107/229 (46%), Positives = 124/229 (54%), Gaps = 38/229 (16%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G PGPPGP G GLPG G +G KGELG PG G+ GP G+ G PGP G PG GP Sbjct: 932 GERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPT 991 Query: 146 GEKGD------LGMMGLPGSRGPMG------------SKGYPGSRGEKGSRGEKGDLGPK 187 G KGD +G G PG RGP+G S+G G G+KGSRGE+G GP Sbjct: 992 GLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPT 1051 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPS 247 G+ G PG G LG G GP GE G +G G PG +G +G KGD+G G PG GP+ Sbjct: 1052 GKDGIPGPLGPLGPPGAAGPSGE---EGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPA 1108 Query: 248 GQPGRPGPPGP-----PPA--GQL----------IMGPKGERGFPGPPG 279 G PG PG G PP GQ ++GP G +G PGPPG Sbjct: 1109 GHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPG 1157 Score = 183 bits (464), Expect = 3e-46 Identities = 106/214 (49%), Positives = 119/214 (55%), Gaps = 25/214 (11%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGR---PGPPGVPGMPGP---IGW 138 QG G+PGP G GP G G+ G GE+G G G KG+ PG PG PG PGP IG+ Sbjct: 748 QGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGF 807 Query: 139 PGPEGPRGEKGDLGMMGLP---GSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP-- 193 PGP GP GEKG G G P G RGP GS+G G G G G KGD+G G G P Sbjct: 808 PGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGE 867 Query: 194 -GFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGK---QGQ---KGDSGVMGPPGKPGP 246 G PG+ G G GPKG PG G G G PG+RG+ QGQ G +GV+GP GK G Sbjct: 868 KGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGE 927 Query: 247 SGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 G G GPPGPP GP GE+G PG GR Sbjct: 928 VGPLGERGPPGPP-------GPPGEQGLPGLEGR 954 Score = 181 bits (458), Expect = 2e-45 Identities = 115/250 (46%), Positives = 123/250 (49%), Gaps = 56/250 (22%) Query: 86 GSLGSPGPPGPQGPPGLPGKTG------------PKGEKGELGRPGRKGR---PGPPGVP 130 G G+ GPPG GPPG PG G KGEKGE G PG KG G G P Sbjct: 692 GEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKP 751 Query: 131 GMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGS------KGYPGSRGEKGSRGEKGDL 184 G PGP G GPEGP+G+ G G G PGS G G GYPG G KGS G G L Sbjct: 752 GAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPL 811 Query: 185 GPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQ---------KGDS 235 GP GEKG G G G +GE GP G G G G TG+PG +G GQ KG Sbjct: 812 GPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLP 871 Query: 236 GVMGPPGKPGPSGQP------GRPGPPG-------------PPPAGQL-------IMGPK 269 G+ GPPG PGP G P GRPG PG P PAG L +GP Sbjct: 872 GLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPL 931 Query: 270 GERGFPGPPG 279 GERG PGPPG Sbjct: 932 GERGPPGPPG 941 Score = 181 bits (458), Expect = 2e-45 Identities = 97/203 (47%), Positives = 110/203 (54%), Gaps = 16/203 (7%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGR------KGRPGPPGVPGMPGPIGWP 139 G +G PGPPG G PG PG G +G G +GR GR KG PGP G PG GP+G Sbjct: 1289 GDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGAR 1348 Query: 140 GPEG---PRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 GP G P G +G G +G PG G G G PG G G G KGD GPKGEKG G Sbjct: 1349 GPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLI 1408 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 G++G GE G KG+ G+ G +GP G G G G G G GPPG GP GQ G G P Sbjct: 1409 GLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSP 1468 Query: 257 GPPPAGQLIMGPKGERGFPGPPG 279 G MGP+G+ G GPPG Sbjct: 1469 GS-------MGPRGDTGPAGPPG 1484 Score = 177 bits (450), Expect = 1e-44 Identities = 96/210 (45%), Positives = 115/210 (54%), Gaps = 11/210 (5%) Query: 82 PCMQGSLGSPGPPGP------QGPPGLPGKTGPKGEKG---ELGRPGRKGRPGPPGVPGM 132 P ++G G PGPPG +GPPGL G+ G G +G +G PG +G PGPPG G Sbjct: 1102 PGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGE 1161 Query: 133 PGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGF 192 G +G GP G G +G G G G+ G G G PG+ GEKG RG+ GD GP G G Sbjct: 1162 VGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGI 1221 Query: 193 PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 PG G +G+KG+ GP G G G +GP G G +G G G G +GPPG PG SG G Sbjct: 1222 PGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGS 1281 Query: 253 PGPPGPP--PAGQLIMGPKGERGFPGPPGR 280 PG G P G G GE G PGPPG+ Sbjct: 1282 PGEKGDPGDVGGPGPPGASGEPGAPGPPGK 1311 Score = 177 bits (448), Expect = 2e-44 Identities = 93/197 (47%), Positives = 114/197 (57%), Gaps = 7/197 (3%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G GPPG +G G PG TG G KG++G+ G G PG G+PG+ GP G+PGP+GP Sbjct: 827 GLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPP 886 Query: 146 GEKGDLGMMGLPGSRGPMGSKGY---PGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK 202 G +G G G PG RG +G +G PG G G +G+ G++GP GE+G PG PG G++ Sbjct: 887 GHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQ 946 Query: 203 GEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAG 262 G G +G G G GP G GK G G +G G G PG PGP+G G GPPGP A Sbjct: 947 GLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGAN 1006 Query: 263 QLIMGPKGERGFPGPPG 279 G GERG GP G Sbjct: 1007 ----GSPGERGPLGPAG 1019 Score = 177 bits (448), Expect = 2e-44 Identities = 107/251 (42%), Positives = 126/251 (50%), Gaps = 53/251 (21%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPG------PPGVPGMPGP 135 P G G PGP GP GPPG G +G +G+KG++G PG KG G PPG PG+ GP Sbjct: 1048 PGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGP 1107 Query: 136 IGWPGPEGPRG------------EKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD 183 G PGP G G +KGD G+ G G GP G +G PG GEKG G+ G Sbjct: 1108 AGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGS 1167 Query: 184 LGPKG------------EKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPG---KRGK 228 +GP G +G PG PG +GQ G +G KGE G AG GP G PG +G Sbjct: 1168 MGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGD 1227 Query: 229 QGQKGDSG---VMGPPGKPGPSGQ------------PGRPGPPGPPPAGQL-----IMGP 268 G+KGDSG GPPGK GP G+ PG GPPG P + G Sbjct: 1228 IGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGD 1287 Query: 269 KGERGFPGPPG 279 G+ G PGPPG Sbjct: 1288 PGDVGGPGPPG 1298 Score = 175 bits (444), Expect = 7e-44 Identities = 100/221 (45%), Positives = 113/221 (51%), Gaps = 31/221 (14%) Query: 86 GSLGSPGPPGPQGP------PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP---- 135 G G+PGP GPQGP PGLPG G G GE G G G PGPPG PG+PGP Sbjct: 1169 GPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDI 1228 Query: 136 -----------IGWPGPEGPRGE---KGDLGMMGLPGSRGPMGS---KGYPGSRGEKGSR 178 G PG +GP GE KG +G GLPG GP G G GS GEKG Sbjct: 1229 GEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDP 1288 Query: 179 GEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVM 238 G+ G GP G G PG PG G++G G G G G +G G PG G G+ G G Sbjct: 1289 GDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGAR 1348 Query: 239 GPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 GPPG+ GP G G PGP G P ++G G+ G PGP G Sbjct: 1349 GPPGRVGPEGLRGIPGPVGEPG----LLGAPGQMGPPGPLG 1385 Score = 173 bits (439), Expect = 2e-43 Identities = 112/271 (41%), Positives = 132/271 (48%), Gaps = 45/271 (16%) Query: 47 PPPPLFPPPF-FRGG--RSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGP------Q 97 PP + PF F GG + P +S + +Q+ Q L GPPGP Sbjct: 438 PPGTVIMMPFQFAGGSFKGPPVS-------FQQAQAQAVLQQTQLSMKGPPGPVGLTGRP 490 Query: 98 GPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRG------EKGDL 151 GP GLPG G KGE+G G G +G GP G PG G +G PG +G RG KGD Sbjct: 491 GPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDR 550 Query: 152 GMMGLPG------SRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 G GLPG RG G G PG GE G RG +G GP G+ G PG G+LG +G Sbjct: 551 GFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSP 610 Query: 206 GPKGEPGIAG---------HRGPTGRPGKRGKQGQKGDSGVMGP------PGKPGPSGQP 250 GP G PG+ G + GP G PG G+QG G G+ GP PG+ GP G P Sbjct: 611 GPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNP 670 Query: 251 GRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 G PG PG P GP GE+G GPPG Sbjct: 671 GIPGLPGSDGPLGHPGHEGPTGEKGAQGPPG 701 Score = 172 bits (436), Expect = 6e-43 Identities = 99/215 (46%), Positives = 118/215 (54%), Gaps = 25/215 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPG------VPGMPGPIGWP 139 GS G GP GP G GLPG++G +G G G+ G +G GPPG +PG GP+G P Sbjct: 1007 GSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPP 1066 Query: 140 GPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGF---P 196 G GP GE+GD G +G PG +G G KG G G+ G RG G GP G G G P Sbjct: 1067 GAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPP 1126 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGP---------S 247 G+ GQKG+ G +G G+ G G G PG G++G+ GD G MGP G PGP Sbjct: 1127 GLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSE 1186 Query: 248 GQPGRPGPPGPPPAGQLIMGPKGER---GFPGPPG 279 G PG PG G P A +G KGER G PGPPG Sbjct: 1187 GTPGLPGGVGQPGA----VGEKGERGDAGDPGPPG 1217 Score = 171 bits (434), Expect = 9e-43 Identities = 104/245 (42%), Positives = 114/245 (46%), Gaps = 47/245 (19%) Query: 82 PCMQGSLGSPGPPGPQG---------PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGM 132 P QG+ GS G PGPQG PPG PG G G G LG PG +G G G G Sbjct: 640 PGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGP 699 Query: 133 PGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGE------------KGSRGE 180 PG G PG GPRG KG G GL G +G G G+PG +G+ G RGE Sbjct: 700 PGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGE 759 Query: 181 KGDLGPK---------------GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGK 225 G GPK GEKG G PG+ G G GPKG G G GP G GK Sbjct: 760 DGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGK 819 Query: 226 RGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-----------PAGQLIMGPKGERGF 274 GK GQ G G GPPG G GQPG G PGP P + + G +G GF Sbjct: 820 SGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGF 879 Query: 275 PGPPG 279 PGP G Sbjct: 880 PGPKG 884 Score = 171 bits (432), Expect = 2e-42 Identities = 96/215 (44%), Positives = 114/215 (53%), Gaps = 17/215 (7%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGV------PGMPGP 135 P +QG G PGP GP G G G+ G G++GELG G+ G PGP GV G GP Sbjct: 871 PGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGP 930 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGF 195 +G GP GP G G+ G+ GL G G G G PG G++G G +G GPKG G PG Sbjct: 931 LGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGP 990 Query: 196 PGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK---------PGP 246 G+ G KG GP G G G RGP G G G GQ G G +GP GK PGP Sbjct: 991 TGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGP 1050 Query: 247 SGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 +G+ G PGP GP PP G +G++G G PG Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPG 1085 Score = 169 bits (429), Expect = 4e-42 Identities = 106/272 (38%), Positives = 130/272 (47%), Gaps = 44/272 (16%) Query: 79 SQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGEL-------------GRP------- 118 S P G G PGPPGP G PG+PG G +G G + G P Sbjct: 406 SGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQ 465 Query: 119 ----------GRKGRPGPPGVPGMPGPIGWPGPEGPRGE---KGDLGMMGLPGSRGPMGS 165 KG PGP G+ G PGP+G PG G +GE +G G GL G GP G Sbjct: 466 AQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGR 525 Query: 166 KGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE------MGPKGEPGIAGHRGP 219 G G G G+RG GD GPKG++GF G PG+ G+KG+ +G G PG G RG Sbjct: 526 VGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGA 585 Query: 220 TGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G PG G+ G+ G G++GP G PGP+G+PG G G P A + GP GE G PG G Sbjct: 586 EGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNV-GPPGEPGPPGQQG 644 Query: 280 ----RCLCGPTMNVNNPSYGESVYGPSSPRVP 307 + L GP + P P P +P Sbjct: 645 NHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLP 676 Score = 168 bits (425), Expect = 1e-41 Identities = 97/221 (43%), Positives = 111/221 (50%), Gaps = 23/221 (10%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P +G +G G GP G G PGK GP GE G G G G PG G PG PG G G Sbjct: 1222 PGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGS 1281 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 G +G+ GD+G G PG+ G G+ G PG RG G G +G G KG KG PG G G+ Sbjct: 1282 PGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGR 1341 Query: 202 KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP--- 258 G MG +G PG G G G PG G+ G G G MGPPG GPSG PG G GP Sbjct: 1342 TGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGE 1401 Query: 259 -----------PP--AGQL-------IMGPKGERGFPGPPG 279 PP AG+ + GP G +G PGPPG Sbjct: 1402 KGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPG 1442 Score = 164 bits (416), Expect = 1e-40 Identities = 94/214 (43%), Positives = 117/214 (54%), Gaps = 26/214 (12%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELG---RPGRKGRPGPPG---VPGMPGPIG 137 ++G +G GPPG QG PG PG+ G G+ G +G PG +G GP G PG+PG +G Sbjct: 1137 VRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVG 1196 Query: 138 WPGPEGPRGEKGDLGMMGLPGSRG---PMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPG 194 PG G +GE+GD G G PG+ G P G G G G G+ G G GP GE G G Sbjct: 1197 QPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKG 1256 Query: 195 FPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPG 254 G G G++GP G+PG++ G G G+KGD G +G PG PG SG+PG PG Sbjct: 1257 SVGPTGLPGDLGPPGDPGVS---------GIDGSPGEKGDPGDVGGPGPPGASGEPGAPG 1307 Query: 255 PPGP-PPAGQL-------IMGPKGERGFPGPPGR 280 PPG P+G + G KGE G GPPGR Sbjct: 1308 PPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGR 1341 Score = 164 bits (416), Expect = 1e-40 Identities = 99/222 (44%), Positives = 115/222 (51%), Gaps = 30/222 (13%) Query: 86 GSLGSPGPPGPQG---------PPGLPGKTGPKGEKGELGRPGRKGRPGPPGV------- 129 G G PGPPG +G P G PG GP+G G G PG G G PG Sbjct: 1148 GLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGER 1207 Query: 130 --PGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGS---RGEKGDL 184 G PGP G PG GP+G+ G+ G G G+ GP G KG PG G KGS G GDL Sbjct: 1208 GDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDL 1267 Query: 185 GPKGE---KGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKR---GKQGQKGDSGVM 238 GP G+ G G PG G G++G G PG +G G G PGKR G G++G G Sbjct: 1268 GPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEK 1327 Query: 239 GPPGKPGPSGQPGRPGPPGP-PPAGQLIMGPKGERGFPGPPG 279 G G+PGP G PGR GP G P G+ +GP+G RG PGP G Sbjct: 1328 GAKGEPGPDGPPGRTGPMGARGPPGR--VGPEGLRGIPGPVG 1367 Score = 160 bits (405), Expect = 2e-39 Identities = 94/218 (43%), Positives = 110/218 (50%), Gaps = 28/218 (12%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKG------------EKGELGRPGRKGRPGPPGVPGMP 133 G +G G PG G GLPG TGPKG EKG+ G G G+PGPPG G Sbjct: 524 GRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGER 583 Query: 134 GPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGE---- 189 G G PGP G GE G G++G GS GP G PG G G+ G KG++GP GE Sbjct: 584 GAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGR---PGVTGIDGAPGAKGNVGPPGEPGPP 640 Query: 190 --------KGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPP 241 +G PG G++G GE GP G PGI G G G G G +G G+ G GPP Sbjct: 641 GQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPP 700 Query: 242 GKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G GP G PG G G + + G KGE+G G PG Sbjct: 701 GSAGPPGYPGPRGVKG-TSGNRGLQGEKGEKGEDGFPG 737 Score = 157 bits (398), Expect = 1e-38 Identities = 83/172 (48%), Positives = 98/172 (56%), Gaps = 6/172 (3%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G G+ G PGP GP PG+TGP G +G GR G +G G PG G PG +G PG GP Sbjct: 1324 EGEKGAKGEPGPDGP---PGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGP 1380 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G G+ GL G GP G KG+ G G G GE G+ KG++G PG G G KG+ Sbjct: 1381 PGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGE---KGDQGLPGVQGPPGPKGD 1437 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 GP G G GH GP G G G++G KG G MGP G GP+G PG PG P Sbjct: 1438 PGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489 Score = 157 bits (396), Expect = 2e-38 Identities = 88/205 (42%), Positives = 106/205 (51%), Gaps = 18/205 (8%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G PGP G G PG G GP+G G GRPG G G PG G GP G PGP G Sbjct: 583 RGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQ 642 Query: 145 RGEKGDLGM------MGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 +G G G+ +G PG +GP G+ G PG G G G G GP GEKG G PG Sbjct: 643 QGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGS 702 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 G G GP+G G +G+RG +G++G+KG+ G G G G G G+PG PGP Sbjct: 703 AGPPGYPGPRGVKGTSGNRG------LQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGP 756 Query: 259 ----PPAGQLIMGPKGERGFPGPPG 279 P G G G+ G GPPG Sbjct: 757 RGEDGPEGP--KGQAGQAGEEGPPG 779 Score = 146 bits (368), Expect = 4e-35 Identities = 79/164 (48%), Positives = 92/164 (56%), Gaps = 15/164 (9%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P G +G+ GPPG GP GL G GP GE G LG PG+ G PGP G G+P G G Sbjct: 1339 PGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLP---GLKGD 1395 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 GP+GEKG +G++GL G PG GEKG +G G GP G KG PG PG +G Sbjct: 1396 TGPKGEKGHIGLIGLIGP---------PGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGS 1446 Query: 202 KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPG 245 G GP PG+AG G G G G G +GD+G GPPG PG Sbjct: 1447 LGHPGP---PGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPG 1487 Score = 115 bits (289), Expect = 6e-26 Identities = 61/120 (50%), Positives = 68/120 (56%), Gaps = 9/120 (7%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGR------PGRKGRPGPPGVPGMPGPIGWP 139 G +G PGP GP G PGL G TGPKGEKG +G PG G G G+PG+ GP G Sbjct: 1376 GQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPK 1435 Query: 140 GPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGML 199 G GP G G LG G PG GP+G KG S+G GS G +GD GP G G PG P L Sbjct: 1436 GDPGPPGPIGSLGHPGPPGVAGPLGQKG---SKGSPGSMGPRGDTGPAGPPGPPGAPAEL 1492 Score = 37.7 bits (86), Expect = 0.021 Identities = 21/50 (42%), Positives = 26/50 (52%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG 134 +GS GSPG GP+G G G GP G EL R+ R P +P + G Sbjct: 1462 KGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEG 1511 Score = 33.5 bits (75), Expect = 0.40 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 26/80 (32%) Query: 225 KRGKQGQKGDSGVMGPPGK-------------PGPSGQPGRPGPP----------GPP-- 259 K ++ ++GD MGP + PG +G+ G G P GPP Sbjct: 338 KAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPG-AGEKGAKGEPAVIEKGQQFEGPPGA 396 Query: 260 PAGQLIMGPKGERGFPGPPG 279 P Q ++GP G G PG PG Sbjct: 397 PGPQGVVGPSGPPGPPGFPG 416 Score = 33.1 bits (74), Expect = 0.52 Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 46 PPPPPLFP-PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 PP P P PP G P + + + + SP G G GP GP GPPG P Sbjct: 1431 PPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPA 1490 Query: 105 K 105 + Sbjct: 1491 E 1491 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 190 bits (482), Expect = 3e-48 Identities = 112/277 (40%), Positives = 129/277 (46%), Gaps = 21/277 (7%) Query: 31 DQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGS 90 D+K GG + P P P P G P P G G+ Sbjct: 168 DEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGP--------------PGEPGEPGA 213 Query: 91 PGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGD 150 GP GP+GPPG PGK G GE G+ GRPG +G PGP G G+PG G PG +G RG G Sbjct: 214 SGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSG- 272 Query: 151 LGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGE 210 + G G GP G KG PGS GE G+ G+ G G GE+G PG PG G +G G G Sbjct: 273 --LDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGA 330 Query: 211 PGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKG 270 G G GP G PG G G KG++G GP G GP G G PGPPGP A GP G Sbjct: 331 AGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAA----GPAG 386 Query: 271 ERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVP 307 G G PG + GPS P+ P Sbjct: 387 NPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423 Score = 185 bits (469), Expect = 8e-47 Identities = 117/278 (42%), Positives = 131/278 (47%), Gaps = 55/278 (19%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 P PP FP G + P S+ P QG G PGPPGP G G G Sbjct: 339 PAGPPGFPGAVGAKGEAGPQGP---------RGSEGP--QGVRGEPGPPGPAGAAGPAGN 387 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSR----- 160 G G+ G G G G G PG PG GP G GP GP G KG+ G G PGS+ Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447 Query: 161 ----GPMGSKGYPGSRGEKGSRGEKGDLGP------------KGEKGFPGFPGMLGQK-- 202 GP+G +G PG GE+G RG +G+ GP G +GFPG G+ G K Sbjct: 448 KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGP 507 Query: 203 -------GEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGP 255 G GPKG PG AG G G PG +G G G G G G PGP+GQ GRPGP Sbjct: 508 AGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGP 567 Query: 256 PGPPPA-GQL----IMGPK---------GERGFPGPPG 279 PGPP A GQ GPK GERG PGPPG Sbjct: 568 PGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPG 605 Score = 182 bits (463), Expect = 4e-46 Identities = 97/195 (49%), Positives = 110/195 (56%), Gaps = 6/195 (3%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G+ G PGP GP GPPG PG G KGE G G G +G G G PG PGP G GP G Sbjct: 329 GAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP 388 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 G G G G G+ G G+ G+PG+RG G +G G GPKG G PG P G KG+ Sbjct: 389 GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAP---GSKGDT 445 Query: 206 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-PAGQL 264 G KGEPG G +GP G G+ GK+G +G+ G G PG PG G PG G PG AG Sbjct: 446 GAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGP- 504 Query: 265 IMGPKGERGFPGPPG 279 GP GERG PGP G Sbjct: 505 -KGPAGERGSPGPAG 518 Score = 182 bits (462), Expect = 5e-46 Identities = 103/226 (45%), Positives = 112/226 (49%), Gaps = 25/226 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPP------GVPGMPGPIGWP 139 G G+ GPPGP GP G G GP+GE G GRPG G PGPP G PG GP G P Sbjct: 887 GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946 Query: 140 GPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGML 199 G GP+G G G++GLPG RG G G PG GE G + GP G G G PG + Sbjct: 947 GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ------GPSGASGERGPPGPM 1000 Query: 200 GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP 259 G G GP GE G G G G PG+ G G KGD G GP G PG G PG PGP GP Sbjct: 1001 GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGP- 1059 Query: 260 PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 G G+RG GP G GP P GP PR Sbjct: 1060 ------AGKSGDRGETGPAGP--AGPV----GPVGARGPAGPQGPR 1093 Score = 180 bits (457), Expect = 2e-45 Identities = 109/257 (42%), Positives = 126/257 (49%), Gaps = 36/257 (14%) Query: 47 PPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGP---------- 96 P PP PP RG + P K E P G G PGPPG Sbjct: 565 PGPP--GPPGARGQAGVMGFPGPKGAAGE------PGKAGERGVPGPPGAVGPAGKDGEA 616 Query: 97 --QGPPGLPGKTGPKGEKGELGRPGRKGRPGP---------PGVPGMPGPIGWPGPEGPR 145 QGPPG G G +GE+G G PG +G PGP PG G+PG +G PGP G R Sbjct: 617 GAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676 Query: 146 GEK---GDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK 202 GE+ G+ G+ G PG GP G+ G PG+ G KG G G G +G G G PG G Sbjct: 677 GERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAA 736 Query: 203 GEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAG 262 G GPKG+ G AG +G G PGK G +G G G GP G PG G+ G GP GP A Sbjct: 737 GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGA- 795 Query: 263 QLIMGPKGERGFPGPPG 279 G G+RG PGPPG Sbjct: 796 ---RGAPGDRGEPGPPG 809 Score = 179 bits (454), Expect = 5e-45 Identities = 106/245 (43%), Positives = 122/245 (49%), Gaps = 50/245 (20%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTG---------PKGEKGELGRPGRKGRPGPPGVPGMPGP 135 +G G+PG PG QG PGL G G PKG++G+ G G G PG GV G+ GP Sbjct: 709 KGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGP 768 Query: 136 IGWPGPEGPRGEKGD---------LGMMGLPGSR------------GPMGSKGYPGSRGE 174 IG PGP G G+KG+ G G PG R GP G+ G PG++GE Sbjct: 769 IGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE 828 Query: 175 KGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGD 234 G G KGD GP G G G PG +G G G KG G AG G TG PG G+ G G Sbjct: 829 PGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGP 888 Query: 235 SGVMGPPGKP---------------GPSGQPGRPGPPGPP-PAGQL----IMGPKGERGF 274 SG GPPG P GP+G+PG GPPGPP PAG+ GP G G Sbjct: 889 SGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGT 948 Query: 275 PGPPG 279 PGP G Sbjct: 949 PGPQG 953 Score = 179 bits (453), Expect = 6e-45 Identities = 99/250 (39%), Positives = 121/250 (48%), Gaps = 30/250 (12%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPG------------------ 125 + G+ G GP GP+G PG PG+ G G+ G G PG +GRPG Sbjct: 273 LDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAG 332 Query: 126 ---------PPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKG 176 PPG PG G G GP+GPRG +G G+ G PG GP G+ G G+ G G Sbjct: 333 PPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADG 392 Query: 177 SRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSG 236 G KG G G G PGFPG G G GP G PG G+ G G PG +G G KG+ G Sbjct: 393 QPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPG 452 Query: 237 VMGPPGKPGPSGQPGRPGPPGPP-PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYG 295 +G G PGP+G+ G+ G G P P G + GP GERG PG G P+ Sbjct: 453 PVGVQGPPGPAGEEGKRGARGEPGPTG--LPGPPGERGGPGSRGFPGADGVAGPKGPAGE 510 Query: 296 ESVYGPSSPR 305 GP+ P+ Sbjct: 511 RGSPGPAGPK 520 Score = 179 bits (453), Expect = 6e-45 Identities = 98/211 (46%), Positives = 113/211 (53%), Gaps = 25/211 (11%) Query: 86 GSLGSPGPPGPQGPPGL---PGKTGPKGEKGELGRPGRKGRPG---------PPGVPGMP 133 G+ G GPPGP GPPGL PG++G +G G G PGR G PG P G PG P Sbjct: 989 GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048 Query: 134 GPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGY------PGSRGEKGSRGEKGDLGPK 187 G G PGP GP G+ GD G G G GP+G G G RG+KG GE+GD G K Sbjct: 1049 GAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIK 1108 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPS 247 G +GF G G G G G +G G +G GP G PG G G+ G +G+ GP G PGP Sbjct: 1109 GHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPR 1168 Query: 248 GQPGRPGPPGPPPAGQLIMGPKGERGFPGPP 278 G+ G GP GPP GP G G PGPP Sbjct: 1169 GRTGDAGPVGPP-------GPPGPPGPPGPP 1192 Score = 175 bits (444), Expect = 7e-44 Identities = 99/225 (44%), Positives = 115/225 (51%), Gaps = 8/225 (3%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P +G G PGP GP+G G PG G KG+ G G PG +G PG G+PG G G PGP Sbjct: 682 PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP 741 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 +G RG+ G G G PG G G G G G G+ G+KG+ GP G G G G G Sbjct: 742 KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD 801 Query: 202 KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPA 261 +GE GP G G AG G G+PG +G+ G G G GPPG GP+G PG G G P A Sbjct: 802 RGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGA 861 Query: 262 --GQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 + GP G GFPG GR GP PS GP P Sbjct: 862 KGARGSAGPPGATGFPGAAGR--VGPP----GPSGNAGPPGPPGP 900 Score = 175 bits (443), Expect = 9e-44 Identities = 109/259 (42%), Positives = 125/259 (48%), Gaps = 29/259 (11%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 PP PP P GG+ P E+ P G GSPG GP G PG PG Sbjct: 894 PPGPP--GPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGP 951 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGP--- 162 G G++G +G PG++G G PG+PG G G GP G GE+G G MG PG GP Sbjct: 952 QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGE 1011 Query: 163 ---------MGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGI 213 GS G GS G KG RGE G GP G G PG PG +G G+ G +GE G Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGP 1071 Query: 214 A---------GHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP----P 260 A G RGP G G RG +G+ G+ G G G G SG G PGPPG P P Sbjct: 1072 AGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGP 1131 Query: 261 AGQLIMGPKGERGFPGPPG 279 +G GP G RG PG G Sbjct: 1132 SG--ASGPAGPRGPPGSAG 1148 Score = 174 bits (440), Expect = 2e-43 Identities = 104/258 (40%), Positives = 120/258 (46%), Gaps = 42/258 (16%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW-- 138 SP G G GP GP GP G PG G G G G G +G PG G PG PGP G+ Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG 815 Query: 139 -------------------------PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRG 173 PGP GP G G +G +G PG++G GS G PG+ G Sbjct: 816 PPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG 875 Query: 174 EKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKG 233 G+ G G GP G G PG PG G++G GP+GE GP GRPG+ G G G Sbjct: 876 FPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGE------TGPAGRPGEVGPPGPPG 929 Query: 234 DSGVMGPPGKPGPSGQPGRPGPPGPPPAGQL----IMGPKGERGFPGPPGRCLCGPTMNV 289 +G G PG GP+G PG PGP G AGQ + G +GERGFPG PG Sbjct: 930 PAGEKGSPGADGPAGAPGTPGPQG--IAGQRGVVGLPGQRGERGFPGLPGP---SGEPGK 984 Query: 290 NNPSYGESVYGPSSPRVP 307 PS GP P P Sbjct: 985 QGPSGASGERGPPGPMGP 1002 Score = 173 bits (438), Expect = 3e-43 Identities = 104/226 (46%), Positives = 119/226 (52%), Gaps = 18/226 (7%) Query: 85 QGSLGSPG---PPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 QG GSPG PGP GPPG GK G +G G+LG PG G G G PG G G PGP Sbjct: 634 QGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGP 693 Query: 142 EGPRGE---------KGDLGMMGLPGSRGPMGSKGYPGSRGEKG---SRGEKGDLGPKGE 189 GPRG KGD G G PGS+G G +G PG RG G +G++GD GPKG Sbjct: 694 AGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753 Query: 190 KGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQ 249 G PG G+ G G +GP G G G +G +G G G G +G G G PG PGP+G Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF 813 Query: 250 PGRPGPPGPPPA-GQL-IMGPKGERGFPGPPGRC-LCGPTMNVNNP 292 G PG G P A G+ G KG+ G PGP G GP NV P Sbjct: 814 AGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAP 859 Score = 171 bits (433), Expect = 1e-42 Identities = 103/256 (40%), Positives = 123/256 (48%), Gaps = 35/256 (13%) Query: 28 PSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGS 87 P+ ++ KRG P P L PP RGG P G+ Sbjct: 462 PAGEEGKRGARGE-----PGPTGLPGPPGERGGPGSRGFP------------------GA 498 Query: 88 LGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGE 147 G GP GP G G PG GPKG GE GRPG G PG G+ G PG PGP+G G Sbjct: 499 DGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGS---PGPDGKTGP 555 Query: 148 KGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGP 207 G G G PG GP G++G G G G +G G+ G GE+G PG PG +G G+ G Sbjct: 556 PGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGE 615 Query: 208 KGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG----PPPAGQ 263 G G G GP G G++G G G G+ GP G PG +G+PG G PG P P+ Sbjct: 616 AGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPS-- 673 Query: 264 LIMGPKGERGFPGPPG 279 G +GERGFPG G Sbjct: 674 ---GARGERGFPGERG 686 Score = 171 bits (432), Expect = 2e-42 Identities = 106/252 (42%), Positives = 123/252 (48%), Gaps = 53/252 (21%) Query: 81 SPCMQGSLGSPGPPGPQGP------------------PGLPGKTGPKGEKGELGRPGRKG 122 SP G G+PG PGPQG PGLPG +G G++G G G +G Sbjct: 936 SPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERG 995 Query: 123 RPGPPGVPGMPGP------------------IGWPGPEGPRGEKGDL---GMMGLPGSRG 161 PGP G PG+ GP G PG +G RGE G G G PG+ G Sbjct: 996 PPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPG 1055 Query: 162 PMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHR---- 217 P+G G G RGE G G G +GP G +G G G G KGE G +G+ GI GHR Sbjct: 1056 PVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSG 1115 Query: 218 --GPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR------PGPPGPP-PAGQL-IMG 267 GP G PG G+QG G SG GP G PG +G PG+ PGP GPP P G+ G Sbjct: 1116 LQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAG 1175 Query: 268 PKGERGFPGPPG 279 P G G PGPPG Sbjct: 1176 PVGPPGPPGPPG 1187 Score = 170 bits (430), Expect = 3e-42 Identities = 107/260 (41%), Positives = 127/260 (48%), Gaps = 34/260 (13%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG 140 +P +G G+ G PGP G G PG G +G++G G PG G PGPPG G PG G+PG Sbjct: 438 APGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG 497 Query: 141 ------PEGPRGE---------KGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLG 185 P+GP GE KG G G PG G G+KG GS G G G+ G G Sbjct: 498 ADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPG 557 Query: 186 PKGEKGFPGFPGMLGQKGEM------GPK---GEPGIAGHRGPTGRPGKRGKQGQKGDSG 236 P G+ G PG PG G +G+ GPK GEPG AG RG G PG G G+ G++G Sbjct: 558 PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAG 617 Query: 237 VMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPS--Y 294 GPPG GP+G+ G GP G P Q + GP G G G PG + PS Sbjct: 618 AQGPPGPAGPAGERGEQGPAG-SPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676 Query: 295 GE-------SVYGPSSPRVP 307 GE V GP P P Sbjct: 677 GERGFPGERGVQGPPGPAGP 696 Score = 169 bits (428), Expect = 5e-42 Identities = 112/273 (41%), Positives = 126/273 (46%), Gaps = 58/273 (21%) Query: 86 GSLGSPGPPGPQGPPGLPGKTG---------------------PKGEKGELGRPGRKGRP 124 G G GPPGPQG GLPG G P G KGE G PG G P Sbjct: 239 GRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP 298 Query: 125 G---PPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYP---GSRGEKGSR 178 G P G+PG G G PGP G RG G G G PG GP G G+P G++GE G + Sbjct: 299 GQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ 358 Query: 179 GEKGDLGPKGEKGFPGFPGML------------GQKGEMGPKGEPGIA------GHRGPT 220 G +G GP+G +G PG PG GQ G G G PGIA G RGP+ Sbjct: 359 GPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPS 418 Query: 221 GRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG----PPPAGQLIMGPKGERGFPG 276 G G G G KG+SG G PG G +G G PGP G P PAG+ G +G RG PG Sbjct: 419 GPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE--EGKRGARGEPG 476 Query: 277 PPGRCLCGPTMNVNNPSY-----GESVYGPSSP 304 P G L GP P + V GP P Sbjct: 477 PTG--LPGPPGERGGPGSRGFPGADGVAGPKGP 507 Score = 167 bits (424), Expect = 1e-41 Identities = 94/196 (47%), Positives = 102/196 (52%), Gaps = 11/196 (5%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G+ G GPPGP GP G PG P G G G G +G GPPG G PG G GP GP Sbjct: 833 GAKGDAGPPGPAGPAGPPG---PIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS 889 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 G G G G G G G +G G G G G G GP GEKG PG G G G Sbjct: 890 GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP 949 Query: 206 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP--PPAGQ 263 GP+ GIAG RG G PG+RG++G G G G PGK GPSG G GPPGP PP Sbjct: 950 GPQ---GIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPG-- 1004 Query: 264 LIMGPKGERGFPGPPG 279 + GP GE G G PG Sbjct: 1005 -LAGPPGESGREGAPG 1019 Score = 165 bits (418), Expect = 7e-41 Identities = 111/295 (37%), Positives = 129/295 (43%), Gaps = 76/295 (25%) Query: 67 PDMKNLMLELETSQSPCMQGSLGSPGPPGPQGP---------PGLP-------------- 103 PD + ET+ +G G GP GP GP PGLP Sbjct: 96 PDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGL 155 Query: 104 --------------------------GKTGPKGEKGELGRPGRKGRPGPPGVPGMP---- 133 G +GP+G G G PG +G GPPG PG P Sbjct: 156 GGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASG 215 Query: 134 --GPIGWPGPEGPRGEKGDLGMMGLPGSR---GPMGSKGYPGS---------RGEKGSRG 179 GP G PGP G G+ G+ G G PG R GP G++G PG+ RG G G Sbjct: 216 PMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDG 275 Query: 180 EKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMG 239 KGD GP G KG PG PG G G+MGP+G P G RG G PG G +G G +G G Sbjct: 276 AKGDAGPAGPKGEPGSPGENGAPGQMGPRGLP---GERGRPGAPGPAGARGNDGATGAAG 332 Query: 240 PPGKPGPSGQPGRPGPPGP-----PPAGQLIMGPKGERGFPGPPGRC-LCGPTMN 288 PPG GP+G PG PG G P + GP+G RG PGPPG GP N Sbjct: 333 PPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN 387 Score = 72.8 bits (177), Expect = 6e-13 Identities = 38/80 (47%), Positives = 43/80 (53%), Gaps = 3/80 (3%) Query: 81 SPCMQGSLGSPGPPGPQGPPG---LPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIG 137 SP QG G+ GP GP+GPPG PGK G G G +G PG +GR G G G PGP G Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPG 1184 Query: 138 WPGPEGPRGEKGDLGMMGLP 157 PGP GP D + P Sbjct: 1185 PPGPPGPPSAGFDFSFLPQP 1204 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 188 bits (478), Expect = 7e-48 Identities = 109/227 (48%), Positives = 125/227 (55%), Gaps = 38/227 (16%) Query: 87 SLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGV---PGMPGPIGWPGPEG 143 S+G PG PGP+G PGLPG G G KG +G PG G PG PG PG+PG G PGP G Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGS---RGEKGSRGEKGDLGPKGEKGF-------- 192 P+G G G GLPG GP+G G+PG GEKG G+ G GP G+KG Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191 Query: 193 ---PGFPGMLGQKGE------------MGPKGEPGIAGH---RGPTGRPGKRGK--QGQK 232 PG PG+ GQKG+ GPKGEPG G +GP G PG G +G K Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 233 GDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G+ G GPPG+PG G PG GPPG P G G KGE+G PG PG Sbjct: 1252 GNPGPQGPPGRPGFQGLPGPEGPPGLPGNG----GIKGEKGNPGQPG 1294 Score = 186 bits (472), Expect = 4e-47 Identities = 109/225 (48%), Positives = 125/225 (55%), Gaps = 30/225 (13%) Query: 85 QGSLGSPGPPGPQGPPG------LPGKTGPKGEKGELGRPGRKGRPGPPGVPGMP---GP 135 +G LGSPG PG G PG LPG GPKGE G + G +G PG PG+PG+P GP Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 136 IGWP--GPEGPRGEKGDLGMMGLPGSRGPMGSKG-------YPGSRGEKGSRGEKGDLGP 186 +G P GP GP GEKG G+ G PG G G KG PG G G+ G GD+G Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679 Query: 187 KGEKGFPGFPGMLGQKGEMGPKGEPGIA--------GHRGPTGRPGKRGKQGQKGDSGVM 238 G+ G PG PG+ G G G G PGI G G G PG G G+ G G Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739 Query: 239 GPPGKPGPSGQPG--RPGPPGPP--PAGQLIMGPKGERGFPGPPG 279 GPPG PGP G+PG PGPPGPP P + +GPKG+RGFPGPPG Sbjct: 740 GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784 Score = 186 bits (471), Expect = 5e-47 Identities = 105/212 (49%), Positives = 122/212 (57%), Gaps = 17/212 (8%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPG--MPGPIGWP 139 P + G G G PG G PGLPG PKGE G G PG +G PGPPG PG + GP G P Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLPG---PKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP 1254 Query: 140 GPEGPRGEKGDLGMMG------LPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP 193 GP+GP G G G+ G LPG+ G G KG PG G G G KGD GP G +G P Sbjct: 1255 GPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP 1314 Query: 194 GFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQ---- 249 G PG+ G KG+ G G PG G +GP+G PG G +G+ G G GPPG PGPSGQ Sbjct: 1315 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII 1374 Query: 250 PGRPGPPGPP--PAGQLIMGPKGERGFPGPPG 279 G GPPG P P + + GP+G +G PGP G Sbjct: 1375 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1406 Score = 182 bits (461), Expect = 7e-46 Identities = 115/265 (43%), Positives = 128/265 (48%), Gaps = 31/265 (11%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 PP PP P P+ P + + E P L PGPPG +G PG+PG Sbjct: 823 PPGPPGIP--------GPIGQPGLHGIPGEKGDPGPP----GLDVPGPPGERGSPGIPGA 870 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGS 165 GP G G G PG+ G G PG G G +G PGP GP G G G+ GL G G G Sbjct: 871 PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQ 930 Query: 166 KGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGK 225 G PG GEKGS+GE G GP G P P +LG KGE G G PGI G GP G G Sbjct: 931 PGLPGPTGEKGSKGEPGLPGPPG----PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGL 986 Query: 226 RGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG--PPPAGQLIMGPKGERGFPGPPGRCLC 283 G GQ G SG G PG PGP G PG PG PG PP + G G+ GFPGP G Sbjct: 987 PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG---LKGTIGDMGFPGPQG---- 1039 Query: 284 GPTMNVNNPSYGESVYG-PSSPRVP 307 V P V G P SP +P Sbjct: 1040 -----VEGPPGPSGVPGQPGSPGLP 1059 Score = 181 bits (460), Expect = 9e-46 Identities = 110/249 (44%), Positives = 130/249 (52%), Gaps = 26/249 (10%) Query: 84 MQGSLGSPGPPGPQGP----------PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMP 133 +QG G+PG PG GP PG PG G G G++G PG G PG PG+PG+P Sbjct: 636 IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695 Query: 134 GP--------IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL- 184 G IG PGP GP+G G G G PG+ G +G +G PG G G +GE G Sbjct: 696 GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755 Query: 185 -GPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 GP G G PGF G LG KG+ G G PG G G G PG +G G G G MGPPG Sbjct: 756 PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815 Query: 244 PGPSGQPGRPGPPG-PPPAGQL-IMGPKGERGFPGPPGRCLCGPTMNVNNPSYGES---V 298 PG G G PGPPG P P GQ + G GE+G PGPPG + GP +P + + Sbjct: 816 PG-IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI 874 Query: 299 YGPSSPRVP 307 P SP +P Sbjct: 875 GPPGSPGLP 883 Score = 181 bits (460), Expect = 9e-46 Identities = 111/246 (45%), Positives = 130/246 (52%), Gaps = 22/246 (8%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 PP PP FP P G + P L P +G+LG G G GPPG PG+ Sbjct: 738 PPGPPGFPGPKGEPGFALPGPPGPPGL---------PGFKGALGPKGDRGFPGPPGPPGR 788 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDL---GMMGLPGSRGP 162 TG G G G G G+PGP G PG+PG IG GP GP G G + G+ G+PG +G Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQPGLHGIPGEKGD 847 Query: 163 MGSKG--YPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPT 220 G G PG GE+GS G G GP G G PG PG G G G KGE G+ G GP Sbjct: 848 PGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907 Query: 221 GR---PGKRGKQGQKGDSGVMGPPGKPGPSGQ---PGRPGPPGPP-PAGQLIMGPKGERG 273 G PG+ G G KGD G+ G PG PGP+G+ G PG PGPP P ++G KGE+G Sbjct: 908 GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG 967 Query: 274 FPGPPG 279 PG PG Sbjct: 968 EPGLPG 973 Score = 179 bits (453), Expect = 6e-45 Identities = 109/252 (43%), Positives = 128/252 (50%), Gaps = 51/252 (20%) Query: 85 QGSLGSPGPPGPQGP--------------PGLPGKTGPKGEKG---ELGRPGRKGR---P 124 +G G PGPPGP P PG+PG +GPKG +G + G+PG G+ P Sbjct: 943 KGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLP 1002 Query: 125 GPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSR------GPMGSKGYPGSRGEKGSR 178 GPPG G PG G PG GP G KG +G MG PG + GP G G PGS G G + Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062 Query: 179 GEKGD-----------LGPKGEKGFPGFPGMLGQKGEMGPKGEPGI---AGHRGPTGRPG 224 G+KGD GPKGE G PG+PG G KG +G G PG+ G +G G PG Sbjct: 1063 GDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG 1122 Query: 225 KRGKQGQKGDSGVMGPPGKPGPSGQP------GRPGPPGPP-----PAGQLIMGPKGERG 273 G G G G+ GPPG PG G+P G PG PGPP P I GP G++G Sbjct: 1123 FPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKG 1182 Query: 274 FPGPPGRCLCGP 285 PG PG GP Sbjct: 1183 EPGQPGFGNPGP 1194 Score = 178 bits (451), Expect = 1e-44 Identities = 125/333 (37%), Positives = 154/333 (46%), Gaps = 77/333 (23%) Query: 15 SGLLCYSAGCLALPSLDQKK--RG-----------GHKACCLLTPPPPPLFPPPFFRGGR 61 +G+ G + LP L +K RG G ++ PP PP FP RG + Sbjct: 351 TGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGE--RGQK 408 Query: 62 SPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGP----------------PGLPGK 105 P + P + G G+PG PGP GP PG PG Sbjct: 409 GDEGPPG-------ISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGS 461 Query: 106 TGPKGEKGELGRPGRKG----------------RPGPPGVPGMPGPIGWPGPEGPRGEKG 149 G KG +GE G G KG +PG PG+PG PG +G+PG +G +G+ G Sbjct: 462 PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521 Query: 150 DLGMMGLPGSRGPMGSKGYPGSRGEKGS-------RGEKGDLGPKGEKGFPGFPGMLGQ- 201 G GLPG G G+ G+PGS+GE G +G+KG+LG G G PG PG GQ Sbjct: 522 ATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQD 581 Query: 202 --KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPP--GKPGP---------SG 248 G GPKGEPG +G G PG G G G+ G MGPP G PGP +G Sbjct: 582 GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641 Query: 249 QPGRPGPPGPP-PAGQLIMGPKGERGFPGPPGR 280 PG+PG PGP GQ I P G+ G PG PGR Sbjct: 642 NPGQPGIPGPKGDPGQTITQP-GKPGLPGNPGR 673 Score = 177 bits (450), Expect = 1e-44 Identities = 108/259 (41%), Positives = 127/259 (49%), Gaps = 46/259 (17%) Query: 60 GRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTG------PKGEKG 113 G SP D + E P ++G G PG PGP+GPPG G+ G P G KG Sbjct: 31 GCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKG 90 Query: 114 ELGRPGRKGRPGPPGVPGMPGPIGWPGPE------GPRGEKGDLGMMGLPGSRGPMGSKG 167 G PG G PG PG+PGMPG G PGP+ G +GE+G G G PG +GP G G Sbjct: 91 IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Query: 168 YPGSRGEKGS------RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTG 221 PG +GE GS G KG+ G G G G PG G G +GP G PG+ G GP G Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 222 RPGKRGK--------QGQKGDSGVMGPPGKPG-------------PSGQPGRPGPPGPPP 260 PG +G +G+KG+ G+ GPPG PG G G PG GPP Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPP- 269 Query: 261 AGQLIMGPKGERGFPGPPG 279 GP G RG PGPPG Sbjct: 270 ------GPPGIRGPPGPPG 282 Score = 177 bits (448), Expect = 2e-44 Identities = 124/345 (35%), Positives = 144/345 (41%), Gaps = 83/345 (24%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGP------------ 93 P P L P G P P E SP G G PGP Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160 Query: 94 ------PGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP------ 141 PGP+G PG PG G +G G G PG G PGPPG+ G PGP G PGP Sbjct: 161 IIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGL 220 Query: 142 --EGPRGEKGDLGMMGLPGSRGPM-------------GSKGYPGSRGEKGSRGEKGDLGP 186 +GP+GEKG+ G+ G PG G + G +G PG RG G G +G GP Sbjct: 221 NFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP 280 Query: 187 ----KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPG 242 KGEKG G PG G+ G+ G G+PGI G G G PG+ G+ G+KG G GPPG Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340 Query: 243 KP----------------------------GPSGQPGRPGPPG-PPPAGQLIMGPKGERG 273 P G G PG GPPG P P G +MGP G G Sbjct: 341 PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG 400 Query: 274 FP---------GPPGRCLCGPTMNVNNPSYG--ESVYGPSSPRVP 307 FP GPPG + GP P GP+ P +P Sbjct: 401 FPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445 Score = 176 bits (446), Expect = 4e-44 Identities = 107/247 (43%), Positives = 125/247 (50%), Gaps = 29/247 (11%) Query: 81 SPCMQGSLGSP---GPPGPQGPPGLPGKTGP--KGEKGELGRPGRKGRPGPPGVPGMPGP 135 +P + G G P G PG QGPPG PG GP +G KG G G GRPG G+PG GP Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGP 1274 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGF 195 G PG G +GEKG+ G GLPG G G +G PG +G G G G G G G PGF Sbjct: 1275 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1334 Query: 196 PGMLGQK---GEMGPKGEPGIAGHRGPTGRPGKRGK----QGQKGDSGVMGPP---GKPG 245 PGM G G GP+GEPG+ G GP G PG G+ +G G G+ G P G PG Sbjct: 1335 PGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1394 Query: 246 PSGQPGRPGPPGPP--------PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGES 297 P G G PGP GPP P G KG+ G PG PG T ++ P + Sbjct: 1395 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPG------TRGLDGPPGPDG 1448 Query: 298 VYGPSSP 304 + GP P Sbjct: 1449 LQGPPGP 1455 Score = 172 bits (436), Expect = 6e-43 Identities = 112/264 (42%), Positives = 138/264 (52%), Gaps = 35/264 (13%) Query: 43 LLTPPPPPLFPPPF------FRG--------------GRSPLLSPDMKNLMLELETSQSP 82 L+ PP PP P P F+G G +S + + +E + Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 83 CMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGP------PGVPGMPGPI 136 + G G PGPPG +GPPG PG G KGEKGE G PG++G+PG PG+PG+PG Sbjct: 262 -LPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 G+PG G GEKG G G PG G + + PG+ G +G G G GEKG GFP Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPR--PGTGITIGEKGNIGLPGLPGEKGERGFP 376 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 G+ G G GP G + G GP G PG+RG++G +G G+ PG PG GQPG PG P Sbjct: 377 GIQGPPGLPGPPGA-AVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPGAPGLP 434 Query: 257 GPP-PAGQLIMGPKGERGFPGPPG 279 GPP PAG I P E PGPPG Sbjct: 435 GPPGPAGPHI-PPSDEICEPGPPG 457 Score = 171 bits (433), Expect = 1e-42 Identities = 101/226 (44%), Positives = 114/226 (50%), Gaps = 35/226 (15%) Query: 79 SQSPCMQGSLGSPGPPGP------------QGPPGLPGKTGPKGEKGELGRPGRKGRPGP 126 S P ++G G+PGP GP +GPPGLPG G KGEKG G+PG G PG Sbjct: 1242 SPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1301 Query: 127 PGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP 186 G G PG G PG G G KGD G+ G+PG G G G PGS G +G G G GP Sbjct: 1302 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1361 Query: 187 -------------KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKG 233 KG+ G PG PG G KG GP+G G+ G GP G PG+ G G G Sbjct: 1362 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDG 1421 Query: 234 DSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G G PG P GQPG G GPP GP G +G PGPPG Sbjct: 1422 AGGRKGDPGLP---GQPGTRGLDGPP-------GPDGLQGPPGPPG 1457 Score = 169 bits (428), Expect = 5e-42 Identities = 116/302 (38%), Positives = 137/302 (45%), Gaps = 85/302 (28%) Query: 82 PCMQGSLGSPGPPG-----PQGPPGLPGKTGPKGEKGELG-----------RPGRKG--- 122 P +QG G PGPPG P GPPG PG+ G KG++G G +PG G Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435 Query: 123 ----------------RPGPPGVPGMPGPIGWPGPEGPRGEKGDL-------------GM 153 PGPPG PG PG G G +G +G+KGD G Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 154 MGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL------GPKGEKGFPG----------FPG 197 GLPG GP GS G+PG +GEKG G G G G GFPG FPG Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555 Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGD------SGVMGPPGKPGPSGQPG 251 M G KGE+G G PG+ G G G+ G G G KG+ G GPPG PG G PG Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615 Query: 252 RPGPPGPPPAGQLIMGPKGERGF------PGPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 GP GPP G GP GE+G PG PG + GP +P G+++ P P Sbjct: 616 NIGPMGPPGFGP--PGPVGEKGIQGVAGNPGQPG--IPGPK---GDP--GQTITQPGKPG 666 Query: 306 VP 307 +P Sbjct: 667 LP 668 Score = 166 bits (419), Expect = 5e-41 Identities = 112/290 (38%), Positives = 128/290 (44%), Gaps = 69/290 (23%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIG------ 137 + G G PG PG GPPG G G KGEKG+ G G KG PG PG PG PG G Sbjct: 489 ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG 548 Query: 138 ----WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE---KGDLGPKGEK 190 +PG +G +GE G G GLPG G G G PG G KG G KG+ GP G Sbjct: 549 DILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNP 608 Query: 191 GFPGFPGML--------------------------GQKGEMGPKGEP------------- 211 G PG PG + GQ G GPKG+P Sbjct: 609 GLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLP 668 Query: 212 ---------GIAGHRGPTGRPGKRGKQGQKGDSGV--MGPPGKPGPSGQPGRPGPPGPP- 259 G+ G G G+PG G G KG+ G+ +G PG PGP G PG PGPPG P Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728 Query: 260 -PAGQLIMGPKGERGFPGP---PGRCLCGPTMNVNNPSYGESVYGPSSPR 305 P + GP G GFPGP PG L GP P + + GP R Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF-KGALGPKGDR 777 Score = 165 bits (417), Expect = 9e-41 Identities = 94/207 (45%), Positives = 113/207 (54%), Gaps = 16/207 (7%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEG 143 ++G G G PG +G PGLPG GP+G PG +G+ G G+PG PGP G GP G Sbjct: 43 IKGEKGERGFPGLEGHPGLPGFPGPEGP------PGPRGQKGDDGIPGPPGPKGIRGPPG 96 Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKG 203 G G G+ G+PG G G +G PG G KG RG G G G +G PG PG+ G KG Sbjct: 97 LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156 Query: 204 EMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG-PPPAG 262 E G + G +G G PG G QG G +G+ GP G PGP G G PGPPG P P G Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216 Query: 263 QL---IMGPKGERGF------PGPPGR 280 + GPKGE+G PGPPG+ Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQ 243 Score = 84.3 bits (207), Expect = 2e-16 Identities = 50/116 (43%), Positives = 59/116 (50%), Gaps = 16/116 (13%) Query: 43 LLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGL 102 L+ PP PP P P G+S ++ D + P + G G G PGPQGP GL Sbjct: 1355 LIGPPGPPGLPGP---SGQSIIIKGD----------AGPPGIPGQPGLKGLPGPQGPQGL 1401 Query: 103 PGKTGPKGEKGELGRP---GRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMG 155 PG TGP G+ G G P G GR G PG+PG PG G GP GP G +G G G Sbjct: 1402 PGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457 >gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] Length = 1142 Score = 188 bits (478), Expect = 7e-48 Identities = 111/254 (43%), Positives = 135/254 (53%), Gaps = 58/254 (22%) Query: 84 MQGSLGSPGPPGPQG---------PPGLPGKTG---PKGEKGELGRPGRKGRPGPPGVPG 131 ++G LG GPPGP+G PP LPG G P+G G+ G+ GR+G+ GPPG PG Sbjct: 362 LKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPG 421 Query: 132 MPGPIGWPGPEGP-----------------------RGEKGDLGMMGLPGSRGPMGSKGY 168 PGP G PG +G +G+KG+ G+ G PGS GP G KG Sbjct: 422 PPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGE 481 Query: 169 PG---SRGEKGSRGEKGDLGPKGEKGFPGFPG------------MLGQKGEMGPKGEPGI 213 PG ++GEKG RGE G +G +G KG PG PG G G MGP+G PG Sbjct: 482 PGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGD 541 Query: 214 AGHRGPTGRPGKRGKQGQKGD-SGVMGPPGKPGPSGQPGRPGP--PGPP-----PAGQLI 265 G G G PGK+G +G+KGD G++GPPG PGP G+ G PG PG P P Sbjct: 542 VGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGP 601 Query: 266 MGPKGERGFPGPPG 279 GPKGERG PG G Sbjct: 602 RGPKGERGLPGVHG 615 Score = 184 bits (466), Expect = 2e-46 Identities = 102/240 (42%), Positives = 124/240 (51%), Gaps = 45/240 (18%) Query: 84 MQGSLGSPGPPGPQGPPGL------PGKTGPKGEKGELGRPGRKGRPGPPGVP------- 130 +QG G PG PGP GPPGL PG TG KGEKG G PG+ G PGPPG+P Sbjct: 766 LQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGM 825 Query: 131 --------GMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKG 182 G+ P +PGP GP G KGD G +G PG+ G G +G+PG +G++G G G Sbjct: 826 SSLYKIKGGVNVP-SYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPG 884 Query: 183 DLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPG 242 G G+ G PG PG+ G+ GE GP G+ G G GP+G+PG GK G G G+MG PG Sbjct: 885 IAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPG 944 Query: 243 KPGPSGQPGRPGPPGP-----------------------PPAGQLIMGPKGERGFPGPPG 279 GP G+ G G PG PP + MG G +G PG PG Sbjct: 945 DRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPG 1004 Score = 174 bits (441), Expect = 1e-43 Identities = 107/256 (41%), Positives = 124/256 (48%), Gaps = 43/256 (16%) Query: 67 PDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGP 126 P +K+ E + P S+ G GP+GPPG+PG+ GPKG KGE G PG G G Sbjct: 704 PGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGD 763 Query: 127 ------PGVPGMPGP---------IGWPGPEGPRGEKGDLGMMGLPGSRGPMG------- 164 PG+PG PGP G PGP G +GEKG G G PG GP G Sbjct: 764 EGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERN 823 Query: 165 -------SKG------YPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEP 211 KG YPG G G +G+ G +G G G PG G G KG+ GP G P Sbjct: 824 GMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPP 883 Query: 212 GIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP--PAGQLIM--- 266 GIAG G G PG G G+ G+ G +G G PGP G G+PG G P Q IM Sbjct: 884 GIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKP 943 Query: 267 ---GPKGERGFPGPPG 279 GPKGERG G PG Sbjct: 944 GDRGPKGERGDQGIPG 959 Score = 166 bits (421), Expect = 3e-41 Identities = 107/280 (38%), Positives = 126/280 (45%), Gaps = 80/280 (28%) Query: 82 PCMQGSLGSPGP---PGPQGPPGLPGKTGPKGEKGELGRPG------RKGRPGPPGVPGM 132 P G G PGP PG G PGL G G KG++G G PG + G PGPPGVPG Sbjct: 844 PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGE 903 Query: 133 PGP------IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP 186 PG IG+PGPEGP G+ G G G+PG++G MG G G +GE+G +G GD G Sbjct: 904 PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGS 963 Query: 187 KGEKGFPGFPGMLGQKGEMGP---KGEPGIAGHRGPTGRPG------------------- 224 +GE+G PG GM G G MGP KG G GH+GP G PG Sbjct: 964 QGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYIN 1023 Query: 225 ----------------------------KRGKQGQKGDSGVMGPPGKPGPSGQPGR---- 252 G+ G G G+ GPPG PGP G G+ Sbjct: 1024 QEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGER 1083 Query: 253 -------PGPPGPPPAGQLIM----GPKGERGFPGPPGRC 281 PG PG P L + G G +G PGP GRC Sbjct: 1084 GEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRC 1123 Score = 160 bits (405), Expect = 2e-39 Identities = 98/228 (42%), Positives = 118/228 (51%), Gaps = 32/228 (14%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P + GS G G PG GPPGL G G KG++G G G + GPPG G+PG G PG Sbjct: 497 PGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPR---GPPGDVGLPGEHGIPGK 553 Query: 142 EGPRGEKGDL-GMMGLPGSRGPMGSKGYPGSR--GEKGSRGEKGDLGPKGEKGFPGFPGM 198 +G +GEKGD G++G PG GP G G PG GE G G G GP+G KG G PG+ Sbjct: 554 QGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGV 613 Query: 199 LGQKGEMGPK--GEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK---PGPSGQPGRP 253 G G++GP+ G PG G +GP G PG +G +G G G G PG PG G+PG P Sbjct: 614 HGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLP 673 Query: 254 GPPGPPPAGQL---------------------IMGPKGERGFPGPPGR 280 GPPG P A L + KGE G G PG+ Sbjct: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGK 721 Score = 158 bits (399), Expect = 1e-38 Identities = 97/258 (37%), Positives = 112/258 (43%), Gaps = 66/258 (25%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPG---------PPGV----- 129 ++G + P PGP GPPG G GP GE G +G PG +G PG PPG+ Sbjct: 831 IKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSG 890 Query: 130 -PGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKG 188 PG PGP G PG G RG GD+G G G G G G G G +G G+ GD GPKG Sbjct: 891 KPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKG 950 Query: 189 EKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPP------- 241 E+G G PG G +GE G G G+ G GP G PG +G G G G G P Sbjct: 951 ERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPA 1010 Query: 242 -------------------------------------------GKPGPSGQPGRPGPPGP 258 G+PGP G+ G PGPPG Sbjct: 1011 DAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPG- 1069 Query: 259 PPAGQLIMGPKGERGFPG 276 P Q G KGERG PG Sbjct: 1070 DPGPQGYRGQKGERGEPG 1087 Score = 157 bits (398), Expect = 1e-38 Identities = 93/215 (43%), Positives = 109/215 (50%), Gaps = 23/215 (10%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVP-GMP--GPIG---- 137 QG G PG GP+G PGLPG G G G GR G+ G PGPPG P +P G IG Sbjct: 634 QGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLK 693 Query: 138 ------WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKG 191 G + KG+ G G PG M KG G RG G G +G G KGE+G Sbjct: 694 NFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERG 753 Query: 192 FPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPG 251 +PG PG +KG+ G +G PGI G GPTG PG G+ G G +G G G GP G+PG Sbjct: 754 YPGIPG---EKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPG 810 Query: 252 RPGPPGPP-------PAGQLIMGPKGERGFPGPPG 279 PGPPG P + I G +PGPPG Sbjct: 811 PPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPG 845 Score = 157 bits (397), Expect = 2e-38 Identities = 110/291 (37%), Positives = 128/291 (43%), Gaps = 75/291 (25%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVP---------G 131 SP +G G PG G G PG PG+ G +G +G G G KG G G P G Sbjct: 302 SPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENG 361 Query: 132 MPGPIGWPGPEGPRGEKGDLGMMG---LPGSRGPMGSKGYPGSRGEKGSRGEKGD----- 183 + G +G GP GP+GEKGD G G LPGS G G +G PG G++G RG+ G Sbjct: 362 LKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPG 421 Query: 184 ------------------------------------LGPKGEKGFPGFPGMLGQKGEMGP 207 G KGE G PGFPG +G KG+ G Sbjct: 422 PPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGE 481 Query: 208 KGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPP---GKPGPSGQPGRP---GPPGPP-- 259 GEP G +G G PG G QG KG+ G GPP G PG GQ G GP GPP Sbjct: 482 PGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGD 541 Query: 260 ---------PAGQLIMGPKGE-RGFPGPPGRCLCGPTMNVNNPSYGESVYG 300 P Q I G KG+ G GPPG L GP P G+S+ G Sbjct: 542 VGLPGEHGIPGKQGIKGEKGDPGGIIGPPG--LPGPKGEAGPP--GKSLPG 588 Score = 157 bits (397), Expect = 2e-38 Identities = 100/241 (41%), Positives = 118/241 (48%), Gaps = 43/241 (17%) Query: 81 SPCMQGSLGSPGPPGPQGPP---------GLPGKTGPKGEKGE-------LGRPGRKGRP 124 SP ++G GS G GP+GPP G+PGK G KGEKG+ G PG KG Sbjct: 520 SPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEA 579 Query: 125 GP-----PGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRG 179 GP PG PG+ G G PGP GP+GE+G G+ G PG GP G G PG G +G G Sbjct: 580 GPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI-GIPGRTGAQGPAG 638 Query: 180 EKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRG-PTGRP--------------- 223 E G GP+G G PG PG G G G G+PG+ G G P P Sbjct: 639 EPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGN 698 Query: 224 ---GKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP--PAGQLIMGPKGERGFPGPP 278 G + KG+ G G PGK + G GP GPP P + G KGERG+PG P Sbjct: 699 CQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIP 758 Query: 279 G 279 G Sbjct: 759 G 759 Score = 157 bits (396), Expect = 2e-38 Identities = 94/223 (42%), Positives = 115/223 (51%), Gaps = 22/223 (9%) Query: 84 MQGSLGSPGPPGPQGPPGLP---GKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG 140 + G GS GP G +G PG P G+ G +GE G +G G KG PG PG PG+ IG PG Sbjct: 466 LPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGL---IGSPG 522 Query: 141 PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL-------GPKGE---- 189 +G +G G +G G PG G G G PG +G KG +G+ G + GPKGE Sbjct: 523 LKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPP 582 Query: 190 -KGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQ--GQKGDSGVMGPPGKPGP 246 K PG PG+ G G GP+G G G G G PG G Q G G +G GP G+PG Sbjct: 583 GKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGI 642 Query: 247 SGQPGRPGPPGPP--PAGQLIMGPKGERGFPGPPGRCLCGPTM 287 G G PG PG P P + G G+ G PGPPG + P + Sbjct: 643 QGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLL 685 Score = 157 bits (396), Expect = 2e-38 Identities = 106/269 (39%), Positives = 121/269 (44%), Gaps = 69/269 (25%) Query: 78 TSQSPCMQGSLGSPGPPGPQGPPG-------------------------LPGKTGPKGEK 112 T +P G G G PG GPPG +PG KGE+ Sbjct: 654 TPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEE 713 Query: 113 GELGRPG------RKGRPGPPGVPGMPGPIGWPGPEGPR------GEKGDLGMMGL---- 156 G G PG RKG GP G PG+PG G G +G R GEKGD G+ G+ Sbjct: 714 GGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIP 773 Query: 157 --PGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM---------------- 198 PG GP G G G G G++GEKG GP G+ G PG PG+ Sbjct: 774 GAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKG 833 Query: 199 -------LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPG 251 G G GPKG+PG G G G PG G G KGD G GPPG G SG+PG Sbjct: 834 GVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPG 893 Query: 252 RPGPPG-PPPAGQLIMGPKGERGFPGPPG 279 PGPPG P G+ GP G+ GFPGP G Sbjct: 894 APGPPGVPGEPGE--RGPVGDIGFPGPEG 920 Score = 155 bits (391), Expect = 9e-38 Identities = 103/247 (41%), Positives = 124/247 (50%), Gaps = 56/247 (22%) Query: 82 PCMQGSLGSPGPPGPQ--GPPGL---PGKTGPKGEKGELGRPGRKGRPG---PPGVPGMP 133 P + G G GPPG G PGL PG GP+G KGE G PG G PG P G+ G+P Sbjct: 570 PGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI-GIP 628 Query: 134 GPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD------LGP- 186 G G GP G G +G G+ GLPG+ G G+ G PG G+ G G GD LG Sbjct: 629 GRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDI 688 Query: 187 ---------------------KGEKGFPGFPGM---LGQKGEMGPKGEPGIAGHRGPTGR 222 KGE+G G PG + +KG++GP+G PGI G GP G Sbjct: 689 GALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGS 748 Query: 223 PGKRGKQG---QKGDSGVMGPPG---KPGPSGQPG---RPGPPGPPPAGQLIMGPKGERG 273 G+RG G +KGD G+ G PG PGP+G PG R G PGP G KGE+G Sbjct: 749 KGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPT-------GAKGEKG 801 Query: 274 FPGPPGR 280 GPPG+ Sbjct: 802 SDGPPGK 808 Score = 152 bits (385), Expect = 5e-37 Identities = 101/278 (36%), Positives = 125/278 (44%), Gaps = 87/278 (31%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPG------KTGPK-----------------GEKGELGRP 118 P + G+ G+PGP GP+G GLPG GP+ G +G G P Sbjct: 590 PGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLP 649 Query: 119 GRKGRPGPPGVPGMPGPIGWPGPEGPRGEK------GDLGMM----------GLPGSRGP 162 G G PG PG G+PG G PG GP G+ GD+G + +PG + Sbjct: 650 GLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSN 709 Query: 163 MGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP------------GFPGMLGQKGEMGPKGE 210 G +G G G+ S KGD+GP+G G P G+PG+ G+KG+ G +G Sbjct: 710 KGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGI 769 Query: 211 PGIAGHRGPTGRPGKRGKQGQ------KGDSGVMGPPGKPGPSGQPG------------- 251 PGI G GPTG PG G+ G KG+ G GPPGKPGP G PG Sbjct: 770 PGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLY 829 Query: 252 ----------RPGPPGPPPAGQLIMGPKGERGFPGPPG 279 PGPPGPP GPKG+ G G PG Sbjct: 830 KIKGGVNVPSYPGPPGPP-------GPKGDPGPVGEPG 860 Score = 144 bits (363), Expect = 2e-34 Identities = 97/256 (37%), Positives = 111/256 (43%), Gaps = 56/256 (21%) Query: 97 QGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGL 156 +G GLPG G G+KG G PG G G PG PG G G+ G +G GEKG+ G G Sbjct: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 Query: 157 P---GSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGI 213 P G G G KG G G G +GEKGD GP G P PG LG +G GP G+ G Sbjct: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGP---PALPGSLGIQGPQGPPGKEGQ 407 Query: 214 AGHRGPTGRPGKRGK-----------------------------------QGQKGDSGVM 238 G RG TG PGK G +G KG++G+ Sbjct: 408 RGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLP 467 Query: 239 GPPGKPGPSGQPGRPGPP----------GPPPAGQLIMGPKGERGFPGPPGRCLCGPTMN 288 G PG GP GQ G PG P P G G KGE G PGPPG + P + Sbjct: 468 GFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGS--QGVKGEPGDPGPPG-LIGSPGLK 524 Query: 289 VNNPSYGESVYGPSSP 304 S G GP P Sbjct: 525 GQQGSAGS--MGPRGP 538 Score = 65.9 bits (159), Expect = 7e-11 Identities = 36/76 (47%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Query: 73 MLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGP-----P 127 ML + P G G PGPPG GP G G+ G +GE G +G PG G PG P Sbjct: 1047 MLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSALGLP 1105 Query: 128 GVPGMPGPIGWPGPEG 143 G PG PGP G PGP G Sbjct: 1106 GSPGAPGPQGPPGPSG 1121 Score = 37.4 bits (85), Expect = 0.028 Identities = 15/24 (62%), Positives = 17/24 (70%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPK 109 G GSPG PGPQGPPG G+ P+ Sbjct: 1103 GLPGSPGAPGPQGPPGPSGRCNPE 1126 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 188 bits (477), Expect = 1e-47 Identities = 108/240 (45%), Positives = 126/240 (52%), Gaps = 44/240 (18%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG--- 140 +QG +G PGP GP G PG G G GE G+ G G KG GPPG PG+ GP+G PG Sbjct: 1118 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG 1177 Query: 141 ---PEGPRGE------KGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP----- 186 GPRG+ KGD G G PG GP+G +G PG GEKG G+ G +GP Sbjct: 1178 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1237 Query: 187 -------KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMG 239 G G G PG +G G +G KGEPG AG+ GP G G G +G++G+ G G Sbjct: 1238 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1297 Query: 240 PPG------------------KPGPSGQPGRPGPPGPP-PAGQ-LIMGPKGERGFPGPPG 279 PPG PGP G PG PGPPG P PAGQ + G KGE G PG PG Sbjct: 1298 PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1357 Score = 185 bits (469), Expect = 8e-47 Identities = 107/222 (48%), Positives = 125/222 (56%), Gaps = 30/222 (13%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP---------- 135 G +G PG PGPQGPPG G+ G GEKG G GR G GP G+PG GP Sbjct: 1081 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1140 Query: 136 --IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGE---K 190 IG PG +G +G+KG+ G G PG +GP+G+ G G GE G RG++G G KG+ + Sbjct: 1141 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1200 Query: 191 GFPGFPGMLGQKGEMGP---KGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK---- 243 GFPG PG +G +G GP KGE G G GP G PG RG QG G G GPPG Sbjct: 1201 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1260 Query: 244 --PGPSGQPGRPGPPGPP-PAGQLIMGPKGER---GFPGPPG 279 G G+PG G PGPP AG + GPKGER G GPPG Sbjct: 1261 GGVGEKGEPGEAGNPGPPGEAG--VGGPKGERGEKGEAGPPG 1300 Score = 184 bits (467), Expect = 1e-46 Identities = 113/251 (45%), Positives = 131/251 (52%), Gaps = 29/251 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G PGPPG QG PG G GP+G G G G +G+PG G+PG GP G PG EG Sbjct: 694 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 753 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK--- 202 GEKG LG PG +GP+G G G +G G RG KG G KGE GFPGF G +G K Sbjct: 754 GEKGALGP---PGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR 810 Query: 203 ---GEMGPKGEPGIAGHR---GPTGRPGKRGKQGQKGDSGVMGPPGKP---GPSGQPGRP 253 G++GP+GE G G + GPTG PG G+ G+KG GV G PG P GP G G P Sbjct: 811 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 870 Query: 254 GPPG-------------PPPAGQL-IMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVY 299 G PG P P GQ GP+G RG GP G+ T + P Sbjct: 871 GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 930 Query: 300 GPSSPRVPVIF 310 GP P+ PV F Sbjct: 931 GPQGPQGPVGF 941 Score = 184 bits (467), Expect = 1e-46 Identities = 99/213 (46%), Positives = 118/213 (55%), Gaps = 19/213 (8%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G +G PGPPGP+GP G G GP+G G +G G G G PG G PGP G G GP+ Sbjct: 1228 GPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1287 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE---KGDLGP---------------K 187 GE+G+ G G PG+ GP G+KG PG G KG+ G GD GP K Sbjct: 1288 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK 1347 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPS 247 GE G PG PG G GE GP G PG G G G G++G++G KG++G GPPGK GP Sbjct: 1348 GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV 1407 Query: 248 GQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 G G G PGP + I GP GE+G PG G+ Sbjct: 1408 GPQGPAGKPGPEGL-RGIPGPVGEQGLPGAAGQ 1439 Score = 183 bits (465), Expect = 2e-46 Identities = 106/226 (46%), Positives = 120/226 (53%), Gaps = 37/226 (16%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGE---KGELGRPGRKGRPGPPGVPGMPGPIGW--- 138 +G G PGPPG QGP G PG G GE +G+ G G+KG G G PG PGPIG Sbjct: 1155 KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL 1214 Query: 139 PGPEGPRGEKGDLGMMGLPGS---------------RGPMGSKGYPGSRGEKGSRGEKGD 183 PGP G +GE GD+G MG PG +GP GS G G GEKG GE G+ Sbjct: 1215 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1274 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 GP GE G G G G+KGE GP G G G +GP G G +G G G G GPPG+ Sbjct: 1275 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1334 Query: 244 PGPSGQ---------PGRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 PGP+GQ G PG PGPP GP GE G PGPPG+ Sbjct: 1335 PGPAGQDGVGGDKGEDGDPGQPGPP-------GPSGEAGPPGPPGK 1373 Score = 183 bits (464), Expect = 3e-46 Identities = 101/210 (48%), Positives = 114/210 (54%), Gaps = 17/210 (8%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G PGPPGP G GLP GP GEKGE G G G PGPPG G GP G GP+GP Sbjct: 1197 EGARGFPGPPGPIGLQGLP---GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1253 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G +G +G G G G+ G PG G G +GE+G+ G G G G PG G G+ Sbjct: 1254 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1313 Query: 205 MGPKGEP---GIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-- 259 GPKG P G G GP G PG G+ G GD G G PG+PGP G G GPPGPP Sbjct: 1314 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK 1373 Query: 260 --PAG-------QLIMGPKGERGFPGPPGR 280 P G Q G KGE G GPPG+ Sbjct: 1374 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGK 1403 Score = 182 bits (463), Expect = 4e-46 Identities = 116/284 (40%), Positives = 137/284 (48%), Gaps = 31/284 (10%) Query: 44 LTPPPPPLFPPPFFRGG---RSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPP 100 L PP + PF GG + P +S +Q+ Q + GPPGP G Sbjct: 497 LPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ-------AQAILQQARIALRGPPGPMGLT 549 Query: 101 GLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSR 160 G PG G G G G G G GP GV G PGP G PG G G G GM G PG++ Sbjct: 550 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 609 Query: 161 GPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHR--- 217 G G G PG G+KG RGE+G GP G PG GM G+ GE+GP+G PG AG R Sbjct: 610 GDRGFDGLPGLPGDKGHRGERGPQGPPGP---PGDDGMRGEDGEIGPRGLPGEAGPRGLL 666 Query: 218 ------GPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG-PPPAGQLIMGPKG 270 G G+PG G G G G MGP G+PGP GQ G PGP G P P G + GP G Sbjct: 667 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI--GPPG 724 Query: 271 ERGFPGPPGRC-LCGPTMNVNNP-----SYGESVYGPSSPRVPV 308 E+G G PG L G +P S + GP P+ P+ Sbjct: 725 EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI 768 Score = 182 bits (463), Expect = 4e-46 Identities = 98/204 (48%), Positives = 111/204 (54%), Gaps = 18/204 (8%) Query: 86 GSLGSPGPPGPQ---GPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPE 142 G G PGPPGP GPPG PGK GP G G GR G KG G G G PG G GP+ Sbjct: 1351 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1410 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK 202 GP G+ G G+ G+P GP+G +G PG+ G+ G G G G G KG PG G G Sbjct: 1411 GPAGKPGPEGLRGIP---GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1467 Query: 203 GEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP--- 259 G +G G PG G +G G PG +G G KGD G+ GP G GP G PG PGP GP Sbjct: 1468 GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNK 1527 Query: 260 ----PAGQLIMGPKGERGFPGPPG 279 PAGQ KG+ G PGPPG Sbjct: 1528 GSTGPAGQ-----KGDSGLPGPPG 1546 Score = 182 bits (461), Expect = 7e-46 Identities = 102/215 (47%), Positives = 113/215 (52%), Gaps = 23/215 (10%) Query: 82 PCMQGSLGSPGPPGPQGPP---GLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 P QG+ G G GPQGPP G PG+ G G G +G PGR G GPPG G G G Sbjct: 1047 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1106 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 GP+GP G G G +GLPG GP GS G G +GE G G+KG G KGE G PG PG+ Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1166 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 GP G PGIAG G G G++G GQKGD G G PG PGP G G PGPPG Sbjct: 1167 ------QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1220 Query: 259 --------------PPAGQLIMGPKGERGFPGPPG 279 PP + GP G G GPPG Sbjct: 1221 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1255 Score = 181 bits (459), Expect = 1e-45 Identities = 98/214 (45%), Positives = 116/214 (54%), Gaps = 20/214 (9%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG----- 140 G G PGPPGP G GLPG G +G KG+ G G G+ GP G+ G PG G PG Sbjct: 994 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1053 Query: 141 -------PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKG---DLGPKGEK 190 P+GP G G G G G+ GP+G G PG +G G GEKG + GP+G Sbjct: 1054 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1113 Query: 191 GFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 G G G +G G GP G PG G +G G PG++G +G KG++G GPPG GP G P Sbjct: 1114 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1173 Query: 251 GRPGPPGPP-PAGQLIM----GPKGERGFPGPPG 279 G G G P P GQ M G +G RGFPGPPG Sbjct: 1174 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1207 Score = 180 bits (457), Expect = 2e-45 Identities = 106/246 (43%), Positives = 123/246 (50%), Gaps = 49/246 (19%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGV------------ 129 P QG+ G G PGPQGP G PG+ GP+G+ G G PG G PG PG Sbjct: 702 PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGP 761 Query: 130 PGMPGPIGWPGPEGP---------RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE 180 PG GPIG+PGP G +G KG+ G G PG +G MG KG G G+ G RGE Sbjct: 762 PGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGE 821 Query: 181 KGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGH------------------------ 216 G GPKG G G PG GQ GE G G PG+ G+ Sbjct: 822 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 881 Query: 217 RGPTGRPGKRGKQ---GQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERG 273 RG G+PG RG++ G +G G GP GKPGP G G GPPG PP + GP+G G Sbjct: 882 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG-PPGERGPQGPQGPVG 940 Query: 274 FPGPPG 279 FPGP G Sbjct: 941 FPGPKG 946 Score = 179 bits (453), Expect = 6e-45 Identities = 97/199 (48%), Positives = 115/199 (57%), Gaps = 9/199 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G LG G PG G PG+ G GP G KG +G +G PGPPG G PGP G PGP+GP Sbjct: 663 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP---QGEPGPPGQQGNPGPQGLPGPQGP 719 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G+ G G PG G G+ G PG G++G GEKG LGP G +G G+PG G KG Sbjct: 720 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 779 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDS---GVMGPPGKPGPSGQPGRPGPPGPP-P 260 G +G G G +G G PG +G G KGD G +GP G+ GP G GR GP G P P Sbjct: 780 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 839 Query: 261 AGQLIMGPKGERGFPGPPG 279 +GQ G KG+ G PG PG Sbjct: 840 SGQ--AGEKGKLGVPGLPG 856 Score = 179 bits (453), Expect = 6e-45 Identities = 96/218 (44%), Positives = 121/218 (55%), Gaps = 30/218 (13%) Query: 85 QGSLGSPGPPGPQG---PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG------- 134 +G G PGP G G PPG PG+ GP+G +G +G PG KG PGPPG G+PG Sbjct: 906 RGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 965 Query: 135 -----------PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD 183 P G GP+GP GE G +G G PG GP G +G PG+ G++G++G+ G Sbjct: 966 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1025 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 G G+ G G G G++G G +G PG+ G GP G PG G G++G +G Sbjct: 1026 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT------ 1079 Query: 244 PGPSGQPGRPGPPGPP-PAGQLIMGPKGERGFPGPPGR 280 GP G PGRPGP GPP PAG+ G GE+G GP GR Sbjct: 1080 AGPIGLPGRPGPQGPPGPAGE--KGAPGEKGPQGPAGR 1115 Score = 178 bits (451), Expect = 1e-44 Identities = 98/209 (46%), Positives = 118/209 (56%), Gaps = 17/209 (8%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G+PG PG G G PG G G +GE G PG++G PGP G+PG GPIG PG +GP Sbjct: 669 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP------KGEKGFPGFPGM 198 +G+ G + GLPG+ GP G G G GEKG+ G G GP +G KG G G+ Sbjct: 729 QGKPG---LAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGL 785 Query: 199 LGQKGEMGP------KGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 G KGE G KG+ G+ G RG G+ G RG+ G +G G GP G PGPSGQ G Sbjct: 786 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 845 Query: 253 PGPPGPP--PAGQLIMGPKGERGFPGPPG 279 G G P P GPKG GFPG PG Sbjct: 846 KGKLGVPGLPGYPGRQGPKGSTGFPGFPG 874 Score = 177 bits (448), Expect = 2e-44 Identities = 93/203 (45%), Positives = 113/203 (55%), Gaps = 4/203 (1%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 QG G PGP G GP G G+TGP GE+G G PG G G PG G G G PGP+G Sbjct: 969 QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1028 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G+ G G+ G PG RG G++G PG +G +G +G G +G GE+G G G +G G Sbjct: 1029 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1088 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP--PPAG 262 GP+G PG AG +G G G +G G+ G G +G PG GP+G PG G G P Sbjct: 1089 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1148 Query: 263 QLIMGPKGERGFPGPPGRCLCGP 285 + G KGE G PGPPG L GP Sbjct: 1149 KGSKGDKGENGPPGPPG--LQGP 1169 Score = 174 bits (440), Expect = 2e-43 Identities = 102/242 (42%), Positives = 119/242 (49%), Gaps = 48/242 (19%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELG------------------------- 116 P +QG G PG PG +GPPG PG G G G G Sbjct: 468 PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 527 Query: 117 --------RPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGY 168 R +G PGP G+ G PGP+G PG G +GE GD G G G +GP G G Sbjct: 528 AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK 587 Query: 169 PGSRGEKGS---RGEKGDLGPKGEKGFPGFPGMLGQKGE------MGPKGEPGIAGHRGP 219 PG RG G+ RG G+ G KG++GF G PG+ G KG GP G PG G RG Sbjct: 588 PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE 647 Query: 220 TGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-PAGQLIMGPKGERGFPGPP 278 G G RG G+ G G++GP G PG GQPG G GPP P G MGP+GE PGPP Sbjct: 648 DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN--MGPQGE---PGPP 702 Query: 279 GR 280 G+ Sbjct: 703 GQ 704 Score = 173 bits (439), Expect = 2e-43 Identities = 93/204 (45%), Positives = 112/204 (54%), Gaps = 19/204 (9%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG------PIGW 138 +G +G GP G GP G G+ GP G+ G G+ G KG+ G PG+PG PG G+ Sbjct: 810 RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 869 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 PG G GEKG G+ G PG P G +G G RG +G+RG G GPKG G G PG Sbjct: 870 PGFPGANGEKGARGVAGKPG---PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 926 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGK---RGKQGQKGDSGVMGPPGKPGPSGQPGRPGP 255 G++G GP+G G G +GP G PGK G GQ+G++G G G PGP G G GP Sbjct: 927 PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 986 Query: 256 PGPPPAGQLIMGPKGERGFPGPPG 279 G GP GERG PGPPG Sbjct: 987 TGE-------TGPIGERGHPGPPG 1003 Score = 171 bits (433), Expect = 1e-42 Identities = 97/208 (46%), Positives = 106/208 (50%), Gaps = 18/208 (8%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G G GPPG GPPG G P G+ G G PG G PG PG PG PGP G G G Sbjct: 1290 RGEKGEAGPPGAAGPPGAKG---PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1346 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSR---GEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 +GE GD G G PG G G G PG R G G+ G +G+ G KGE G G PG G Sbjct: 1347 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1406 Query: 202 KGEMGPKGEPGIAGHR---GPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 G GP G+PG G R GP G G G GQ G G MGPPG PG G PG G G Sbjct: 1407 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1466 Query: 259 P-------PAGQLIMGPKGERGFPGPPG 279 P P G+ G KG+RG PG G Sbjct: 1467 PGLIGLIGPPGE--QGEKGDRGLPGTQG 1492 Score = 171 bits (432), Expect = 2e-42 Identities = 98/214 (45%), Positives = 110/214 (51%), Gaps = 20/214 (9%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGR---------PGRKGRPGPPGVPGMPGPI 136 G G PG G GPPG G GPKGE+GE G PG KG PG G G PGP+ Sbjct: 1264 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1323 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGY---PGSRGEKGSRGEKGDLGPKGEKGFP 193 G+PG GP GE G G G+ G +G G G PG GE G G G GP G G Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1383 Query: 194 GFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRP 253 G G G KGE G +G PG G GP G GK G +G +G G +G G PG +GQ G P Sbjct: 1384 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1443 Query: 254 GPPGPP--PAGQLIMGPKGERGFP------GPPG 279 GP GPP P + G KGE+G P GPPG Sbjct: 1444 GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1477 Score = 169 bits (428), Expect = 5e-42 Identities = 102/234 (43%), Positives = 113/234 (48%), Gaps = 14/234 (5%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P G G G G G PG PG+ GPKG G G PG G G GV G PGP G GP Sbjct: 837 PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 896 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 GPRG +G G G PG +G G G PG GE+G +G +G +G G KG PG PG G Sbjct: 897 TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 956 Query: 202 KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG---- 257 G G +GE G G GP G G G QG G++G +G G PGP G PG G PG Sbjct: 957 PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1016 Query: 258 ------PPPAG-QLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 P P G GP G RGFPG G L G GE GP P Sbjct: 1017 EGAKGDPGPQGISGKDGPAGLRGFPGERG--LPG-AQGAPGLKGGEGPQGPPGP 1067 Score = 168 bits (425), Expect = 1e-41 Identities = 95/209 (45%), Positives = 109/209 (52%), Gaps = 11/209 (5%) Query: 82 PCMQGSLGSPGPPGPQGP------PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP 135 P G G PG PG +G PGLPG G +GE+G G PG G G G G GP Sbjct: 594 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 653 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGE---KGF 192 G PG GPRG G G G PG G G G PG +G G +GE G G +G +G Sbjct: 654 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 713 Query: 193 PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 PG G +G GE GP+G+PG+AG G G PG GK+GQ G+ G +GPPG GP G PG Sbjct: 714 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 773 Query: 253 PGPPGPPPAGQL--IMGPKGERGFPGPPG 279 G G L G KGE GFPG G Sbjct: 774 RGVKGADGVRGLKGSKGEKGEDGFPGFKG 802 Score = 101 bits (252), Expect = 1e-21 Identities = 77/234 (32%), Positives = 92/234 (39%), Gaps = 69/234 (29%) Query: 93 PPGPQGPPGLPGKTG-PKGEKGELGRPGRKGRPGPPGV--PGMPGPIGWPGPEGPRGEKG 149 PP + PG+P +T + G G KG+ G P V PGM EGP G G Sbjct: 408 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML-------VEGPPGPAG 460 Query: 150 DLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE----- 204 G+MG PG +GP G G PG RG G PG PG G G Sbjct: 461 PAGIMGPPGLQGPTGPPGDPGDRGPPGR---------------PGLPGADGLPGPPGTML 505 Query: 205 ----------------------------------MGPKGEPGIAGHRGPTGRPGKRGKQG 230 GP G G+ G GP G PG G +G Sbjct: 506 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 565 Query: 231 QKGDSGVMGP---PGKPGPSGQPGRPGPPGPPPAGQL--IMGPKGERGFPGPPG 279 + GD G GP G PGP+G+PG+ G PG + G KG+RGF G PG Sbjct: 566 ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPG 619 Score = 72.4 bits (176), Expect = 8e-13 Identities = 36/63 (57%), Positives = 38/63 (60%), Gaps = 3/63 (4%) Query: 78 TSQSPCMQGSLGSPGPPGP---QGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG 134 T SP +G G PGP GP GPPGLPG GPKG KG G G+KG G PG PG PG Sbjct: 1490 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549 Query: 135 PIG 137 P G Sbjct: 1550 PPG 1552 Score = 68.9 bits (167), Expect = 9e-12 Identities = 46/125 (36%), Positives = 54/125 (43%), Gaps = 23/125 (18%) Query: 186 PKGEKGFPGFPGML----------GQKGEMGPKGEPGIAGHRGPTGRPGK--RGKQGQKG 233 P E+ PG P G GE G KGEP + PG G G G Sbjct: 408 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-------EPGMLVEGPPGPAG 460 Query: 234 DSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPS 293 +G+MGPPG GP+G PG PG GPP G G G PGPPG L P + S Sbjct: 461 PAGIMGPPGLQGPTGPPGDPGDRGPPGRP----GLPGADGLPGPPGTMLMLPFRYGGDGS 516 Query: 294 YGESV 298 G ++ Sbjct: 517 KGPTI 521 Score = 66.2 bits (160), Expect = 6e-11 Identities = 33/58 (56%), Positives = 35/58 (60%), Gaps = 3/58 (5%) Query: 82 PCMQGSLGSPGPP---GPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPI 136 P G LG PGPP GPQGP G G TGP G+KG+ G PG G PGPPG P PI Sbjct: 1503 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1560 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 188 bits (477), Expect = 1e-47 Identities = 108/240 (45%), Positives = 126/240 (52%), Gaps = 44/240 (18%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG--- 140 +QG +G PGP GP G PG G G GE G+ G G KG GPPG PG+ GP+G PG Sbjct: 1067 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG 1126 Query: 141 ---PEGPRGE------KGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP----- 186 GPRG+ KGD G G PG GP+G +G PG GEKG G+ G +GP Sbjct: 1127 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1186 Query: 187 -------KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMG 239 G G G PG +G G +G KGEPG AG+ GP G G G +G++G+ G G Sbjct: 1187 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1246 Query: 240 PPG------------------KPGPSGQPGRPGPPGPP-PAGQ-LIMGPKGERGFPGPPG 279 PPG PGP G PG PGPPG P PAGQ + G KGE G PG PG Sbjct: 1247 PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1306 Score = 185 bits (469), Expect = 8e-47 Identities = 107/222 (48%), Positives = 125/222 (56%), Gaps = 30/222 (13%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP---------- 135 G +G PG PGPQGPPG G+ G GEKG G GR G GP G+PG GP Sbjct: 1030 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089 Query: 136 --IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGE---K 190 IG PG +G +G+KG+ G G PG +GP+G+ G G GE G RG++G G KG+ + Sbjct: 1090 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1149 Query: 191 GFPGFPGMLGQKGEMGP---KGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK---- 243 GFPG PG +G +G GP KGE G G GP G PG RG QG G G GPPG Sbjct: 1150 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1209 Query: 244 --PGPSGQPGRPGPPGPP-PAGQLIMGPKGER---GFPGPPG 279 G G+PG G PGPP AG + GPKGER G GPPG Sbjct: 1210 GGVGEKGEPGEAGNPGPPGEAG--VGGPKGERGEKGEAGPPG 1249 Score = 184 bits (467), Expect = 1e-46 Identities = 113/251 (45%), Positives = 131/251 (52%), Gaps = 29/251 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G PGPPG QG PG G GP+G G G G +G+PG G+PG GP G PG EG Sbjct: 643 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 702 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK--- 202 GEKG LG PG +GP+G G G +G G RG KG G KGE GFPGF G +G K Sbjct: 703 GEKGALGP---PGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR 759 Query: 203 ---GEMGPKGEPGIAGHR---GPTGRPGKRGKQGQKGDSGVMGPPGKP---GPSGQPGRP 253 G++GP+GE G G + GPTG PG G+ G+KG GV G PG P GP G G P Sbjct: 760 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 819 Query: 254 GPPG-------------PPPAGQL-IMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVY 299 G PG P P GQ GP+G RG GP G+ T + P Sbjct: 820 GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 879 Query: 300 GPSSPRVPVIF 310 GP P+ PV F Sbjct: 880 GPQGPQGPVGF 890 Score = 184 bits (467), Expect = 1e-46 Identities = 99/213 (46%), Positives = 118/213 (55%), Gaps = 19/213 (8%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G +G PGPPGP+GP G G GP+G G +G G G G PG G PGP G G GP+ Sbjct: 1177 GPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1236 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE---KGDLGP---------------K 187 GE+G+ G G PG+ GP G+KG PG G KG+ G GD GP K Sbjct: 1237 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK 1296 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPS 247 GE G PG PG G GE GP G PG G G G G++G++G KG++G GPPGK GP Sbjct: 1297 GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV 1356 Query: 248 GQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 G G G PGP + I GP GE+G PG G+ Sbjct: 1357 GPQGPAGKPGPEGL-RGIPGPVGEQGLPGAAGQ 1388 Score = 183 bits (465), Expect = 2e-46 Identities = 106/226 (46%), Positives = 120/226 (53%), Gaps = 37/226 (16%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGE---KGELGRPGRKGRPGPPGVPGMPGPIGW--- 138 +G G PGPPG QGP G PG G GE +G+ G G+KG G G PG PGPIG Sbjct: 1104 KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL 1163 Query: 139 PGPEGPRGEKGDLGMMGLPGS---------------RGPMGSKGYPGSRGEKGSRGEKGD 183 PGP G +GE GD+G MG PG +GP GS G G GEKG GE G+ Sbjct: 1164 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1223 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 GP GE G G G G+KGE GP G G G +GP G G +G G G G GPPG+ Sbjct: 1224 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283 Query: 244 PGPSGQ---------PGRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 PGP+GQ G PG PGPP GP GE G PGPPG+ Sbjct: 1284 PGPAGQDGVGGDKGEDGDPGQPGPP-------GPSGEAGPPGPPGK 1322 Score = 183 bits (464), Expect = 3e-46 Identities = 101/210 (48%), Positives = 114/210 (54%), Gaps = 17/210 (8%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G PGPPGP G GLP GP GEKGE G G G PGPPG G GP G GP+GP Sbjct: 1146 EGARGFPGPPGPIGLQGLP---GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1202 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G +G +G G G G+ G PG G G +GE+G+ G G G G PG G G+ Sbjct: 1203 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1262 Query: 205 MGPKGEP---GIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-- 259 GPKG P G G GP G PG G+ G GD G G PG+PGP G G GPPGPP Sbjct: 1263 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK 1322 Query: 260 --PAG-------QLIMGPKGERGFPGPPGR 280 P G Q G KGE G GPPG+ Sbjct: 1323 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGK 1352 Score = 182 bits (463), Expect = 4e-46 Identities = 116/284 (40%), Positives = 137/284 (48%), Gaps = 31/284 (10%) Query: 44 LTPPPPPLFPPPFFRGG---RSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPP 100 L PP + PF GG + P +S +Q+ Q + GPPGP G Sbjct: 446 LPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ-------AQAILQQARIALRGPPGPMGLT 498 Query: 101 GLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSR 160 G PG G G G G G G GP GV G PGP G PG G G G GM G PG++ Sbjct: 499 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 558 Query: 161 GPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHR--- 217 G G G PG G+KG RGE+G GP G PG GM G+ GE+GP+G PG AG R Sbjct: 559 GDRGFDGLPGLPGDKGHRGERGPQGPPGP---PGDDGMRGEDGEIGPRGLPGEAGPRGLL 615 Query: 218 ------GPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG-PPPAGQLIMGPKG 270 G G+PG G G G G MGP G+PGP GQ G PGP G P P G + GP G Sbjct: 616 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI--GPPG 673 Query: 271 ERGFPGPPGRC-LCGPTMNVNNP-----SYGESVYGPSSPRVPV 308 E+G G PG L G +P S + GP P+ P+ Sbjct: 674 EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI 717 Score = 182 bits (463), Expect = 4e-46 Identities = 98/204 (48%), Positives = 111/204 (54%), Gaps = 18/204 (8%) Query: 86 GSLGSPGPPGPQ---GPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPE 142 G G PGPPGP GPPG PGK GP G G GR G KG G G G PG G GP+ Sbjct: 1300 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1359 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK 202 GP G+ G G+ G+P GP+G +G PG+ G+ G G G G G KG PG G G Sbjct: 1360 GPAGKPGPEGLRGIP---GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1416 Query: 203 GEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP--- 259 G +G G PG G +G G PG +G G KGD G+ GP G GP G PG PGP GP Sbjct: 1417 GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNK 1476 Query: 260 ----PAGQLIMGPKGERGFPGPPG 279 PAGQ KG+ G PGPPG Sbjct: 1477 GSTGPAGQ-----KGDSGLPGPPG 1495 Score = 182 bits (461), Expect = 7e-46 Identities = 102/215 (47%), Positives = 113/215 (52%), Gaps = 23/215 (10%) Query: 82 PCMQGSLGSPGPPGPQGPP---GLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 P QG+ G G GPQGPP G PG+ G G G +G PGR G GPPG G G G Sbjct: 996 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1055 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 GP+GP G G G +GLPG GP GS G G +GE G G+KG G KGE G PG PG+ Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1115 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 GP G PGIAG G G G++G GQKGD G G PG PGP G G PGPPG Sbjct: 1116 ------QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1169 Query: 259 --------------PPAGQLIMGPKGERGFPGPPG 279 PP + GP G G GPPG Sbjct: 1170 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1204 Score = 181 bits (459), Expect = 1e-45 Identities = 98/214 (45%), Positives = 116/214 (54%), Gaps = 20/214 (9%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG----- 140 G G PGPPGP G GLPG G +G KG+ G G G+ GP G+ G PG G PG Sbjct: 943 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002 Query: 141 -------PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKG---DLGPKGEK 190 P+GP G G G G G+ GP+G G PG +G G GEKG + GP+G Sbjct: 1003 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1062 Query: 191 GFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 G G G +G G GP G PG G +G G PG++G +G KG++G GPPG GP G P Sbjct: 1063 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1122 Query: 251 GRPGPPGPP-PAGQLIM----GPKGERGFPGPPG 279 G G G P P GQ M G +G RGFPGPPG Sbjct: 1123 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1156 Score = 180 bits (457), Expect = 2e-45 Identities = 106/246 (43%), Positives = 123/246 (50%), Gaps = 49/246 (19%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGV------------ 129 P QG+ G G PGPQGP G PG+ GP+G+ G G PG G PG PG Sbjct: 651 PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGP 710 Query: 130 PGMPGPIGWPGPEGP---------RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE 180 PG GPIG+PGP G +G KG+ G G PG +G MG KG G G+ G RGE Sbjct: 711 PGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGE 770 Query: 181 KGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGH------------------------ 216 G GPKG G G PG GQ GE G G PG+ G+ Sbjct: 771 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 830 Query: 217 RGPTGRPGKRGKQ---GQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERG 273 RG G+PG RG++ G +G G GP GKPGP G G GPPG PP + GP+G G Sbjct: 831 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG-PPGERGPQGPQGPVG 889 Query: 274 FPGPPG 279 FPGP G Sbjct: 890 FPGPKG 895 Score = 179 bits (453), Expect = 6e-45 Identities = 97/199 (48%), Positives = 115/199 (57%), Gaps = 9/199 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G LG G PG G PG+ G GP G KG +G +G PGPPG G PGP G PGP+GP Sbjct: 612 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP---QGEPGPPGQQGNPGPQGLPGPQGP 668 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G+ G G PG G G+ G PG G++G GEKG LGP G +G G+PG G KG Sbjct: 669 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 728 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDS---GVMGPPGKPGPSGQPGRPGPPGPP-P 260 G +G G G +G G PG +G G KGD G +GP G+ GP G GR GP G P P Sbjct: 729 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788 Query: 261 AGQLIMGPKGERGFPGPPG 279 +GQ G KG+ G PG PG Sbjct: 789 SGQ--AGEKGKLGVPGLPG 805 Score = 179 bits (453), Expect = 6e-45 Identities = 96/218 (44%), Positives = 121/218 (55%), Gaps = 30/218 (13%) Query: 85 QGSLGSPGPPGPQG---PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG------- 134 +G G PGP G G PPG PG+ GP+G +G +G PG KG PGPPG G+PG Sbjct: 855 RGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 914 Query: 135 -----------PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD 183 P G GP+GP GE G +G G PG GP G +G PG+ G++G++G+ G Sbjct: 915 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 974 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 G G+ G G G G++G G +G PG+ G GP G PG G G++G +G Sbjct: 975 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT------ 1028 Query: 244 PGPSGQPGRPGPPGPP-PAGQLIMGPKGERGFPGPPGR 280 GP G PGRPGP GPP PAG+ G GE+G GP GR Sbjct: 1029 AGPIGLPGRPGPQGPPGPAGE--KGAPGEKGPQGPAGR 1064 Score = 178 bits (451), Expect = 1e-44 Identities = 98/209 (46%), Positives = 118/209 (56%), Gaps = 17/209 (8%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G+PG PG G G PG G G +GE G PG++G PGP G+PG GPIG PG +GP Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP------KGEKGFPGFPGM 198 +G+ G + GLPG+ GP G G G GEKG+ G G GP +G KG G G+ Sbjct: 678 QGKPG---LAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGL 734 Query: 199 LGQKGEMGP------KGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 G KGE G KG+ G+ G RG G+ G RG+ G +G G GP G PGPSGQ G Sbjct: 735 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 794 Query: 253 PGPPGPP--PAGQLIMGPKGERGFPGPPG 279 G G P P GPKG GFPG PG Sbjct: 795 KGKLGVPGLPGYPGRQGPKGSTGFPGFPG 823 Score = 177 bits (448), Expect = 2e-44 Identities = 93/203 (45%), Positives = 113/203 (55%), Gaps = 4/203 (1%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 QG G PGP G GP G G+TGP GE+G G PG G G PG G G G PGP+G Sbjct: 918 QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 977 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G+ G G+ G PG RG G++G PG +G +G +G G +G GE+G G G +G G Sbjct: 978 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1037 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP--PPAG 262 GP+G PG AG +G G G +G G+ G G +G PG GP+G PG G G P Sbjct: 1038 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1097 Query: 263 QLIMGPKGERGFPGPPGRCLCGP 285 + G KGE G PGPPG L GP Sbjct: 1098 KGSKGDKGENGPPGPPG--LQGP 1118 Score = 174 bits (440), Expect = 2e-43 Identities = 102/242 (42%), Positives = 119/242 (49%), Gaps = 48/242 (19%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELG------------------------- 116 P +QG G PG PG +GPPG PG G G G G Sbjct: 417 PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 476 Query: 117 --------RPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGY 168 R +G PGP G+ G PGP+G PG G +GE GD G G G +GP G G Sbjct: 477 AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK 536 Query: 169 PGSRGEKGS---RGEKGDLGPKGEKGFPGFPGMLGQKGE------MGPKGEPGIAGHRGP 219 PG RG G+ RG G+ G KG++GF G PG+ G KG GP G PG G RG Sbjct: 537 PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE 596 Query: 220 TGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-PAGQLIMGPKGERGFPGPP 278 G G RG G+ G G++GP G PG GQPG G GPP P G MGP+GE PGPP Sbjct: 597 DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN--MGPQGE---PGPP 651 Query: 279 GR 280 G+ Sbjct: 652 GQ 653 Score = 173 bits (439), Expect = 2e-43 Identities = 93/204 (45%), Positives = 112/204 (54%), Gaps = 19/204 (9%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG------PIGW 138 +G +G GP G GP G G+ GP G+ G G+ G KG+ G PG+PG PG G+ Sbjct: 759 RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 818 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 PG G GEKG G+ G PG P G +G G RG +G+RG G GPKG G G PG Sbjct: 819 PGFPGANGEKGARGVAGKPG---PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 875 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGK---RGKQGQKGDSGVMGPPGKPGPSGQPGRPGP 255 G++G GP+G G G +GP G PGK G GQ+G++G G G PGP G G GP Sbjct: 876 PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 935 Query: 256 PGPPPAGQLIMGPKGERGFPGPPG 279 G GP GERG PGPPG Sbjct: 936 TGE-------TGPIGERGHPGPPG 952 Score = 171 bits (433), Expect = 1e-42 Identities = 97/208 (46%), Positives = 106/208 (50%), Gaps = 18/208 (8%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G G GPPG GPPG G P G+ G G PG G PG PG PG PGP G G G Sbjct: 1239 RGEKGEAGPPGAAGPPGAKG---PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1295 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSR---GEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 +GE GD G G PG G G G PG R G G+ G +G+ G KGE G G PG G Sbjct: 1296 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355 Query: 202 KGEMGPKGEPGIAGHR---GPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 G GP G+PG G R GP G G G GQ G G MGPPG PG G PG G G Sbjct: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1415 Query: 259 P-------PAGQLIMGPKGERGFPGPPG 279 P P G+ G KG+RG PG G Sbjct: 1416 PGLIGLIGPPGE--QGEKGDRGLPGTQG 1441 Score = 171 bits (432), Expect = 2e-42 Identities = 98/214 (45%), Positives = 110/214 (51%), Gaps = 20/214 (9%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGR---------PGRKGRPGPPGVPGMPGPI 136 G G PG G GPPG G GPKGE+GE G PG KG PG G G PGP+ Sbjct: 1213 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGY---PGSRGEKGSRGEKGDLGPKGEKGFP 193 G+PG GP GE G G G+ G +G G G PG GE G G G GP G G Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332 Query: 194 GFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRP 253 G G G KGE G +G PG G GP G GK G +G +G G +G G PG +GQ G P Sbjct: 1333 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1392 Query: 254 GPPGPP--PAGQLIMGPKGERGFP------GPPG 279 GP GPP P + G KGE+G P GPPG Sbjct: 1393 GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1426 Score = 169 bits (428), Expect = 5e-42 Identities = 102/234 (43%), Positives = 113/234 (48%), Gaps = 14/234 (5%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P G G G G G PG PG+ GPKG G G PG G G GV G PGP G GP Sbjct: 786 PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 845 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 GPRG +G G G PG +G G G PG GE+G +G +G +G G KG PG PG G Sbjct: 846 TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 905 Query: 202 KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG---- 257 G G +GE G G GP G G G QG G++G +G G PGP G PG G PG Sbjct: 906 PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 965 Query: 258 ------PPPAG-QLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 P P G GP G RGFPG G L G GE GP P Sbjct: 966 EGAKGDPGPQGISGKDGPAGLRGFPGERG--LPG-AQGAPGLKGGEGPQGPPGP 1016 Score = 168 bits (425), Expect = 1e-41 Identities = 95/209 (45%), Positives = 109/209 (52%), Gaps = 11/209 (5%) Query: 82 PCMQGSLGSPGPPGPQGP------PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP 135 P G G PG PG +G PGLPG G +GE+G G PG G G G G GP Sbjct: 543 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 602 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGE---KGF 192 G PG GPRG G G G PG G G G PG +G G +GE G G +G +G Sbjct: 603 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 662 Query: 193 PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 PG G +G GE GP+G+PG+AG G G PG GK+GQ G+ G +GPPG GP G PG Sbjct: 663 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 722 Query: 253 PGPPGPPPAGQL--IMGPKGERGFPGPPG 279 G G L G KGE GFPG G Sbjct: 723 RGVKGADGVRGLKGSKGEKGEDGFPGFKG 751 Score = 101 bits (252), Expect = 1e-21 Identities = 77/234 (32%), Positives = 92/234 (39%), Gaps = 69/234 (29%) Query: 93 PPGPQGPPGLPGKTG-PKGEKGELGRPGRKGRPGPPGV--PGMPGPIGWPGPEGPRGEKG 149 PP + PG+P +T + G G KG+ G P V PGM EGP G G Sbjct: 357 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML-------VEGPPGPAG 409 Query: 150 DLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE----- 204 G+MG PG +GP G G PG RG G PG PG G G Sbjct: 410 PAGIMGPPGLQGPTGPPGDPGDRGPPGR---------------PGLPGADGLPGPPGTML 454 Query: 205 ----------------------------------MGPKGEPGIAGHRGPTGRPGKRGKQG 230 GP G G+ G GP G PG G +G Sbjct: 455 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 514 Query: 231 QKGDSGVMGP---PGKPGPSGQPGRPGPPGPPPAGQL--IMGPKGERGFPGPPG 279 + GD G GP G PGP+G+PG+ G PG + G KG+RGF G PG Sbjct: 515 ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPG 568 Score = 72.4 bits (176), Expect = 8e-13 Identities = 36/63 (57%), Positives = 38/63 (60%), Gaps = 3/63 (4%) Query: 78 TSQSPCMQGSLGSPGPPGP---QGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG 134 T SP +G G PGP GP GPPGLPG GPKG KG G G+KG G PG PG PG Sbjct: 1439 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498 Query: 135 PIG 137 P G Sbjct: 1499 PPG 1501 Score = 68.9 bits (167), Expect = 9e-12 Identities = 46/125 (36%), Positives = 54/125 (43%), Gaps = 23/125 (18%) Query: 186 PKGEKGFPGFPGML----------GQKGEMGPKGEPGIAGHRGPTGRPGK--RGKQGQKG 233 P E+ PG P G GE G KGEP + PG G G G Sbjct: 357 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-------EPGMLVEGPPGPAG 409 Query: 234 DSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPS 293 +G+MGPPG GP+G PG PG GPP G G G PGPPG L P + S Sbjct: 410 PAGIMGPPGLQGPTGPPGDPGDRGPPGRP----GLPGADGLPGPPGTMLMLPFRYGGDGS 465 Query: 294 YGESV 298 G ++ Sbjct: 466 KGPTI 470 Score = 66.2 bits (160), Expect = 6e-11 Identities = 33/58 (56%), Positives = 35/58 (60%), Gaps = 3/58 (5%) Query: 82 PCMQGSLGSPGPP---GPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPI 136 P G LG PGPP GPQGP G G TGP G+KG+ G PG G PGPPG P PI Sbjct: 1452 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1509 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 188 bits (477), Expect = 1e-47 Identities = 108/240 (45%), Positives = 126/240 (52%), Gaps = 44/240 (18%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG--- 140 +QG +G PGP GP G PG G G GE G+ G G KG GPPG PG+ GP+G PG Sbjct: 1106 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG 1165 Query: 141 ---PEGPRGE------KGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP----- 186 GPRG+ KGD G G PG GP+G +G PG GEKG G+ G +GP Sbjct: 1166 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1225 Query: 187 -------KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMG 239 G G G PG +G G +G KGEPG AG+ GP G G G +G++G+ G G Sbjct: 1226 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1285 Query: 240 PPG------------------KPGPSGQPGRPGPPGPP-PAGQ-LIMGPKGERGFPGPPG 279 PPG PGP G PG PGPPG P PAGQ + G KGE G PG PG Sbjct: 1286 PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1345 Score = 185 bits (469), Expect = 8e-47 Identities = 107/222 (48%), Positives = 125/222 (56%), Gaps = 30/222 (13%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP---------- 135 G +G PG PGPQGPPG G+ G GEKG G GR G GP G+PG GP Sbjct: 1069 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1128 Query: 136 --IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGE---K 190 IG PG +G +G+KG+ G G PG +GP+G+ G G GE G RG++G G KG+ + Sbjct: 1129 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1188 Query: 191 GFPGFPGMLGQKGEMGP---KGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK---- 243 GFPG PG +G +G GP KGE G G GP G PG RG QG G G GPPG Sbjct: 1189 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1248 Query: 244 --PGPSGQPGRPGPPGPP-PAGQLIMGPKGER---GFPGPPG 279 G G+PG G PGPP AG + GPKGER G GPPG Sbjct: 1249 GGVGEKGEPGEAGNPGPPGEAG--VGGPKGERGEKGEAGPPG 1288 Score = 184 bits (467), Expect = 1e-46 Identities = 113/251 (45%), Positives = 131/251 (52%), Gaps = 29/251 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G PGPPG QG PG G GP+G G G G +G+PG G+PG GP G PG EG Sbjct: 682 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 741 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK--- 202 GEKG LG PG +GP+G G G +G G RG KG G KGE GFPGF G +G K Sbjct: 742 GEKGALGP---PGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR 798 Query: 203 ---GEMGPKGEPGIAGHR---GPTGRPGKRGKQGQKGDSGVMGPPGKP---GPSGQPGRP 253 G++GP+GE G G + GPTG PG G+ G+KG GV G PG P GP G G P Sbjct: 799 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 858 Query: 254 GPPG-------------PPPAGQL-IMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVY 299 G PG P P GQ GP+G RG GP G+ T + P Sbjct: 859 GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 918 Query: 300 GPSSPRVPVIF 310 GP P+ PV F Sbjct: 919 GPQGPQGPVGF 929 Score = 184 bits (467), Expect = 1e-46 Identities = 99/213 (46%), Positives = 118/213 (55%), Gaps = 19/213 (8%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G +G PGPPGP+GP G G GP+G G +G G G G PG G PGP G G GP+ Sbjct: 1216 GPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1275 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE---KGDLGP---------------K 187 GE+G+ G G PG+ GP G+KG PG G KG+ G GD GP K Sbjct: 1276 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK 1335 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPS 247 GE G PG PG G GE GP G PG G G G G++G++G KG++G GPPGK GP Sbjct: 1336 GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV 1395 Query: 248 GQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 G G G PGP + I GP GE+G PG G+ Sbjct: 1396 GPQGPAGKPGPEGL-RGIPGPVGEQGLPGAAGQ 1427 Score = 183 bits (465), Expect = 2e-46 Identities = 106/226 (46%), Positives = 120/226 (53%), Gaps = 37/226 (16%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGE---KGELGRPGRKGRPGPPGVPGMPGPIGW--- 138 +G G PGPPG QGP G PG G GE +G+ G G+KG G G PG PGPIG Sbjct: 1143 KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL 1202 Query: 139 PGPEGPRGEKGDLGMMGLPGS---------------RGPMGSKGYPGSRGEKGSRGEKGD 183 PGP G +GE GD+G MG PG +GP GS G G GEKG GE G+ Sbjct: 1203 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1262 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 GP GE G G G G+KGE GP G G G +GP G G +G G G G GPPG+ Sbjct: 1263 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1322 Query: 244 PGPSGQ---------PGRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 PGP+GQ G PG PGPP GP GE G PGPPG+ Sbjct: 1323 PGPAGQDGVGGDKGEDGDPGQPGPP-------GPSGEAGPPGPPGK 1361 Score = 183 bits (464), Expect = 3e-46 Identities = 101/210 (48%), Positives = 114/210 (54%), Gaps = 17/210 (8%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G PGPPGP G GLP GP GEKGE G G G PGPPG G GP G GP+GP Sbjct: 1185 EGARGFPGPPGPIGLQGLP---GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1241 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G +G +G G G G+ G PG G G +GE+G+ G G G G PG G G+ Sbjct: 1242 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1301 Query: 205 MGPKGEP---GIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-- 259 GPKG P G G GP G PG G+ G GD G G PG+PGP G G GPPGPP Sbjct: 1302 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK 1361 Query: 260 --PAG-------QLIMGPKGERGFPGPPGR 280 P G Q G KGE G GPPG+ Sbjct: 1362 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGK 1391 Score = 182 bits (463), Expect = 4e-46 Identities = 116/284 (40%), Positives = 137/284 (48%), Gaps = 31/284 (10%) Query: 44 LTPPPPPLFPPPFFRGG---RSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPP 100 L PP + PF GG + P +S +Q+ Q + GPPGP G Sbjct: 485 LPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ-------AQAILQQARIALRGPPGPMGLT 537 Query: 101 GLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSR 160 G PG G G G G G G GP GV G PGP G PG G G G GM G PG++ Sbjct: 538 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 597 Query: 161 GPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHR--- 217 G G G PG G+KG RGE+G GP G PG GM G+ GE+GP+G PG AG R Sbjct: 598 GDRGFDGLPGLPGDKGHRGERGPQGPPGP---PGDDGMRGEDGEIGPRGLPGEAGPRGLL 654 Query: 218 ------GPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG-PPPAGQLIMGPKG 270 G G+PG G G G G MGP G+PGP GQ G PGP G P P G + GP G Sbjct: 655 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI--GPPG 712 Query: 271 ERGFPGPPGRC-LCGPTMNVNNP-----SYGESVYGPSSPRVPV 308 E+G G PG L G +P S + GP P+ P+ Sbjct: 713 EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI 756 Score = 182 bits (463), Expect = 4e-46 Identities = 98/204 (48%), Positives = 111/204 (54%), Gaps = 18/204 (8%) Query: 86 GSLGSPGPPGPQ---GPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPE 142 G G PGPPGP GPPG PGK GP G G GR G KG G G G PG G GP+ Sbjct: 1339 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1398 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK 202 GP G+ G G+ G+P GP+G +G PG+ G+ G G G G G KG PG G G Sbjct: 1399 GPAGKPGPEGLRGIP---GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1455 Query: 203 GEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP--- 259 G +G G PG G +G G PG +G G KGD G+ GP G GP G PG PGP GP Sbjct: 1456 GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNK 1515 Query: 260 ----PAGQLIMGPKGERGFPGPPG 279 PAGQ KG+ G PGPPG Sbjct: 1516 GSTGPAGQ-----KGDSGLPGPPG 1534 Score = 182 bits (461), Expect = 7e-46 Identities = 102/215 (47%), Positives = 113/215 (52%), Gaps = 23/215 (10%) Query: 82 PCMQGSLGSPGPPGPQGPP---GLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 P QG+ G G GPQGPP G PG+ G G G +G PGR G GPPG G G G Sbjct: 1035 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1094 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 GP+GP G G G +GLPG GP GS G G +GE G G+KG G KGE G PG PG+ Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 GP G PGIAG G G G++G GQKGD G G PG PGP G G PGPPG Sbjct: 1155 ------QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1208 Query: 259 --------------PPAGQLIMGPKGERGFPGPPG 279 PP + GP G G GPPG Sbjct: 1209 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1243 Score = 181 bits (459), Expect = 1e-45 Identities = 98/214 (45%), Positives = 116/214 (54%), Gaps = 20/214 (9%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG----- 140 G G PGPPGP G GLPG G +G KG+ G G G+ GP G+ G PG G PG Sbjct: 982 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1041 Query: 141 -------PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKG---DLGPKGEK 190 P+GP G G G G G+ GP+G G PG +G G GEKG + GP+G Sbjct: 1042 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1101 Query: 191 GFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 G G G +G G GP G PG G +G G PG++G +G KG++G GPPG GP G P Sbjct: 1102 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1161 Query: 251 GRPGPPGPP-PAGQLIM----GPKGERGFPGPPG 279 G G G P P GQ M G +G RGFPGPPG Sbjct: 1162 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1195 Score = 180 bits (457), Expect = 2e-45 Identities = 106/246 (43%), Positives = 123/246 (50%), Gaps = 49/246 (19%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGV------------ 129 P QG+ G G PGPQGP G PG+ GP+G+ G G PG G PG PG Sbjct: 690 PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGP 749 Query: 130 PGMPGPIGWPGPEGP---------RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE 180 PG GPIG+PGP G +G KG+ G G PG +G MG KG G G+ G RGE Sbjct: 750 PGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGE 809 Query: 181 KGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGH------------------------ 216 G GPKG G G PG GQ GE G G PG+ G+ Sbjct: 810 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 869 Query: 217 RGPTGRPGKRGKQ---GQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERG 273 RG G+PG RG++ G +G G GP GKPGP G G GPPG PP + GP+G G Sbjct: 870 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG-PPGERGPQGPQGPVG 928 Query: 274 FPGPPG 279 FPGP G Sbjct: 929 FPGPKG 934 Score = 179 bits (453), Expect = 6e-45 Identities = 97/199 (48%), Positives = 115/199 (57%), Gaps = 9/199 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G LG G PG G PG+ G GP G KG +G +G PGPPG G PGP G PGP+GP Sbjct: 651 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP---QGEPGPPGQQGNPGPQGLPGPQGP 707 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G+ G G PG G G+ G PG G++G GEKG LGP G +G G+PG G KG Sbjct: 708 IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 767 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDS---GVMGPPGKPGPSGQPGRPGPPGPP-P 260 G +G G G +G G PG +G G KGD G +GP G+ GP G GR GP G P P Sbjct: 768 DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 827 Query: 261 AGQLIMGPKGERGFPGPPG 279 +GQ G KG+ G PG PG Sbjct: 828 SGQ--AGEKGKLGVPGLPG 844 Score = 179 bits (453), Expect = 6e-45 Identities = 96/218 (44%), Positives = 121/218 (55%), Gaps = 30/218 (13%) Query: 85 QGSLGSPGPPGPQG---PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG------- 134 +G G PGP G G PPG PG+ GP+G +G +G PG KG PGPPG G+PG Sbjct: 894 RGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 953 Query: 135 -----------PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD 183 P G GP+GP GE G +G G PG GP G +G PG+ G++G++G+ G Sbjct: 954 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1013 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 G G+ G G G G++G G +G PG+ G GP G PG G G++G +G Sbjct: 1014 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT------ 1067 Query: 244 PGPSGQPGRPGPPGPP-PAGQLIMGPKGERGFPGPPGR 280 GP G PGRPGP GPP PAG+ G GE+G GP GR Sbjct: 1068 AGPIGLPGRPGPQGPPGPAGE--KGAPGEKGPQGPAGR 1103 Score = 178 bits (451), Expect = 1e-44 Identities = 98/209 (46%), Positives = 118/209 (56%), Gaps = 17/209 (8%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G+PG PG G G PG G G +GE G PG++G PGP G+PG GPIG PG +GP Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP------KGEKGFPGFPGM 198 +G+ G + GLPG+ GP G G G GEKG+ G G GP +G KG G G+ Sbjct: 717 QGKPG---LAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGL 773 Query: 199 LGQKGEMGP------KGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 G KGE G KG+ G+ G RG G+ G RG+ G +G G GP G PGPSGQ G Sbjct: 774 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 833 Query: 253 PGPPGPP--PAGQLIMGPKGERGFPGPPG 279 G G P P GPKG GFPG PG Sbjct: 834 KGKLGVPGLPGYPGRQGPKGSTGFPGFPG 862 Score = 177 bits (448), Expect = 2e-44 Identities = 93/203 (45%), Positives = 113/203 (55%), Gaps = 4/203 (1%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 QG G PGP G GP G G+TGP GE+G G PG G G PG G G G PGP+G Sbjct: 957 QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1016 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G+ G G+ G PG RG G++G PG +G +G +G G +G GE+G G G +G G Sbjct: 1017 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1076 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP--PPAG 262 GP+G PG AG +G G G +G G+ G G +G PG GP+G PG G G P Sbjct: 1077 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1136 Query: 263 QLIMGPKGERGFPGPPGRCLCGP 285 + G KGE G PGPPG L GP Sbjct: 1137 KGSKGDKGENGPPGPPG--LQGP 1157 Score = 174 bits (440), Expect = 2e-43 Identities = 102/242 (42%), Positives = 119/242 (49%), Gaps = 48/242 (19%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELG------------------------- 116 P +QG G PG PG +GPPG PG G G G G Sbjct: 456 PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 515 Query: 117 --------RPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGY 168 R +G PGP G+ G PGP+G PG G +GE GD G G G +GP G G Sbjct: 516 AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK 575 Query: 169 PGSRGEKGS---RGEKGDLGPKGEKGFPGFPGMLGQKGE------MGPKGEPGIAGHRGP 219 PG RG G+ RG G+ G KG++GF G PG+ G KG GP G PG G RG Sbjct: 576 PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE 635 Query: 220 TGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-PAGQLIMGPKGERGFPGPP 278 G G RG G+ G G++GP G PG GQPG G GPP P G MGP+GE PGPP Sbjct: 636 DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN--MGPQGE---PGPP 690 Query: 279 GR 280 G+ Sbjct: 691 GQ 692 Score = 173 bits (439), Expect = 2e-43 Identities = 93/204 (45%), Positives = 112/204 (54%), Gaps = 19/204 (9%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG------PIGW 138 +G +G GP G GP G G+ GP G+ G G+ G KG+ G PG+PG PG G+ Sbjct: 798 RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 857 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 PG G GEKG G+ G PG P G +G G RG +G+RG G GPKG G G PG Sbjct: 858 PGFPGANGEKGARGVAGKPG---PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 914 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGK---RGKQGQKGDSGVMGPPGKPGPSGQPGRPGP 255 G++G GP+G G G +GP G PGK G GQ+G++G G G PGP G G GP Sbjct: 915 PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 974 Query: 256 PGPPPAGQLIMGPKGERGFPGPPG 279 G GP GERG PGPPG Sbjct: 975 TGE-------TGPIGERGHPGPPG 991 Score = 171 bits (433), Expect = 1e-42 Identities = 97/208 (46%), Positives = 106/208 (50%), Gaps = 18/208 (8%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G G GPPG GPPG G P G+ G G PG G PG PG PG PGP G G G Sbjct: 1278 RGEKGEAGPPGAAGPPGAKG---PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1334 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSR---GEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 +GE GD G G PG G G G PG R G G+ G +G+ G KGE G G PG G Sbjct: 1335 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394 Query: 202 KGEMGPKGEPGIAGHR---GPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 G GP G+PG G R GP G G G GQ G G MGPPG PG G PG G G Sbjct: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1454 Query: 259 P-------PAGQLIMGPKGERGFPGPPG 279 P P G+ G KG+RG PG G Sbjct: 1455 PGLIGLIGPPGE--QGEKGDRGLPGTQG 1480 Score = 171 bits (432), Expect = 2e-42 Identities = 98/214 (45%), Positives = 110/214 (51%), Gaps = 20/214 (9%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGR---------PGRKGRPGPPGVPGMPGPI 136 G G PG G GPPG G GPKGE+GE G PG KG PG G G PGP+ Sbjct: 1252 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGY---PGSRGEKGSRGEKGDLGPKGEKGFP 193 G+PG GP GE G G G+ G +G G G PG GE G G G GP G G Sbjct: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371 Query: 194 GFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRP 253 G G G KGE G +G PG G GP G GK G +G +G G +G G PG +GQ G P Sbjct: 1372 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1431 Query: 254 GPPGPP--PAGQLIMGPKGERGFP------GPPG 279 GP GPP P + G KGE+G P GPPG Sbjct: 1432 GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1465 Score = 169 bits (428), Expect = 5e-42 Identities = 102/234 (43%), Positives = 113/234 (48%), Gaps = 14/234 (5%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P G G G G G PG PG+ GPKG G G PG G G GV G PGP G GP Sbjct: 825 PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 884 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 GPRG +G G G PG +G G G PG GE+G +G +G +G G KG PG PG G Sbjct: 885 TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 944 Query: 202 KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG---- 257 G G +GE G G GP G G G QG G++G +G G PGP G PG G PG Sbjct: 945 PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1004 Query: 258 ------PPPAG-QLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 P P G GP G RGFPG G L G GE GP P Sbjct: 1005 EGAKGDPGPQGISGKDGPAGLRGFPGERG--LPG-AQGAPGLKGGEGPQGPPGP 1055 Score = 168 bits (425), Expect = 1e-41 Identities = 95/209 (45%), Positives = 109/209 (52%), Gaps = 11/209 (5%) Query: 82 PCMQGSLGSPGPPGPQGP------PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP 135 P G G PG PG +G PGLPG G +GE+G G PG G G G G GP Sbjct: 582 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 641 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGE---KGF 192 G PG GPRG G G G PG G G G PG +G G +GE G G +G +G Sbjct: 642 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 701 Query: 193 PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 PG G +G GE GP+G+PG+AG G G PG GK+GQ G+ G +GPPG GP G PG Sbjct: 702 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 761 Query: 253 PGPPGPPPAGQL--IMGPKGERGFPGPPG 279 G G L G KGE GFPG G Sbjct: 762 RGVKGADGVRGLKGSKGEKGEDGFPGFKG 790 Score = 101 bits (252), Expect = 1e-21 Identities = 77/234 (32%), Positives = 92/234 (39%), Gaps = 69/234 (29%) Query: 93 PPGPQGPPGLPGKTG-PKGEKGELGRPGRKGRPGPPGV--PGMPGPIGWPGPEGPRGEKG 149 PP + PG+P +T + G G KG+ G P V PGM EGP G G Sbjct: 396 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML-------VEGPPGPAG 448 Query: 150 DLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE----- 204 G+MG PG +GP G G PG RG G PG PG G G Sbjct: 449 PAGIMGPPGLQGPTGPPGDPGDRGPPGR---------------PGLPGADGLPGPPGTML 493 Query: 205 ----------------------------------MGPKGEPGIAGHRGPTGRPGKRGKQG 230 GP G G+ G GP G PG G +G Sbjct: 494 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 553 Query: 231 QKGDSGVMGP---PGKPGPSGQPGRPGPPGPPPAGQL--IMGPKGERGFPGPPG 279 + GD G GP G PGP+G+PG+ G PG + G KG+RGF G PG Sbjct: 554 ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPG 607 Score = 72.4 bits (176), Expect = 8e-13 Identities = 36/63 (57%), Positives = 38/63 (60%), Gaps = 3/63 (4%) Query: 78 TSQSPCMQGSLGSPGPPGP---QGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG 134 T SP +G G PGP GP GPPGLPG GPKG KG G G+KG G PG PG PG Sbjct: 1478 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537 Query: 135 PIG 137 P G Sbjct: 1538 PPG 1540 Score = 68.9 bits (167), Expect = 9e-12 Identities = 46/125 (36%), Positives = 54/125 (43%), Gaps = 23/125 (18%) Query: 186 PKGEKGFPGFPGML----------GQKGEMGPKGEPGIAGHRGPTGRPGK--RGKQGQKG 233 P E+ PG P G GE G KGEP + PG G G G Sbjct: 396 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-------EPGMLVEGPPGPAG 448 Query: 234 DSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPS 293 +G+MGPPG GP+G PG PG GPP G G G PGPPG L P + S Sbjct: 449 PAGIMGPPGLQGPTGPPGDPGDRGPPGRP----GLPGADGLPGPPGTMLMLPFRYGGDGS 504 Query: 294 YGESV 298 G ++ Sbjct: 505 KGPTI 509 Score = 66.2 bits (160), Expect = 6e-11 Identities = 33/58 (56%), Positives = 35/58 (60%), Gaps = 3/58 (5%) Query: 82 PCMQGSLGSPGPP---GPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPI 136 P G LG PGPP GPQGP G G TGP G+KG+ G PG G PGPPG P PI Sbjct: 1491 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1548 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 188 bits (477), Expect = 1e-47 Identities = 112/264 (42%), Positives = 136/264 (51%), Gaps = 22/264 (8%) Query: 48 PPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTG 107 P P PP G R P P L E G G PG PG G G G+ G Sbjct: 2011 PGPQGPPGLALGERGP---PGPSGLAGE---------PGKPGIPGLPGRAGGVGEAGRPG 2058 Query: 108 PKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPE------GPRGEKGDLGMMGLPGSRG 161 +GE+GE G G +GR GPPG+PG PGP G PGP+ GP G G+ G GL G++G Sbjct: 2059 ERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGP-GLSGEQGPPGLKGAKG 2117 Query: 162 PMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTG 221 GS G G +G++G G KGD G G +G G PG+ G++G GP+G+PG+ G RGP G Sbjct: 2118 EPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPG 2177 Query: 222 RPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRC 281 G G G G G+ GP G GPSG G PG GPP G+ + GP G G PGPPG Sbjct: 2178 PVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPP--GRGLTGPTGAVGLPGPPGPS 2235 Query: 282 -LCGPTMNVNNPSYGESVYGPSSP 304 L GP + P P +P Sbjct: 2236 GLVGPQGSPGLPGQVGETGKPGAP 2259 Score = 184 bits (468), Expect = 1e-46 Identities = 112/247 (45%), Positives = 131/247 (53%), Gaps = 42/247 (17%) Query: 55 PFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGP------------PGPQGPPGL 102 P RG R P P ++ + P + G G PGP PGP+GPPGL Sbjct: 1337 PGERGPRGPKGEPGAPGQVIG---GEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGL 1393 Query: 103 PGKT--GPKGEKGELGRPG------RKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDL--G 152 PG G KG++GE G PG G PG PG+PG PGP G GP G +GEKGD G Sbjct: 1394 PGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDG 1453 Query: 153 MMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPG 212 GLPG PGS GE+G RG G +GPKG++GFPG G G+KGE GP PG Sbjct: 1454 APGLPGQ---------PGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGP---PG 1501 Query: 213 IAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGER 272 AG R G PG G+ G KG G GP G+ G G+PGRPG P G + GPKGE+ Sbjct: 1502 PAGSR---GLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPA--VVGPAVAGPKGEK 1556 Query: 273 GFPGPPG 279 G GP G Sbjct: 1557 GDVGPAG 1563 Score = 176 bits (447), Expect = 3e-44 Identities = 120/291 (41%), Positives = 146/291 (50%), Gaps = 37/291 (12%) Query: 48 PPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCM---QGSLGSPGPPGPQGPPGLPG 104 P L PP RG R D+ + L+ + S + G G+ G G +GP GL G Sbjct: 2491 PRGLTGPPGSRGERGE--KGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDG 2548 Query: 105 KTGPKGE------KGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPG 158 GP+G+ KG G PG KG G PG+ G+ GP G PG G G+ G G G+PG Sbjct: 2549 DKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPG 2608 Query: 159 SRGPMGSKGYPGSRGEKGSRGEKG------DLGPKGEKGFPGFPGMLGQKGEMGPKGEPG 212 RG G G+ G RG KG RG KG + G KGE G PG PG+ G KGEMG G PG Sbjct: 2609 IRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPG 2668 Query: 213 IAG------------HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP- 259 +G RG G+PG +G QG+KG+ G G G PGPSG G GPPGPP Sbjct: 2669 QSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPG 2728 Query: 260 ---PAG-QLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVY-GPSSPR 305 P G + + G KGERG PG R + P + GE GP+ PR Sbjct: 2729 SVGPRGPEGLQGQKGERGPPGE--RVVGAPGVPGAPGERGEQGRPGPAGPR 2777 Score = 176 bits (445), Expect = 5e-44 Identities = 104/240 (43%), Positives = 127/240 (52%), Gaps = 43/240 (17%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGE---------LGRPGRKG------RPGP 126 P ++G LG PG PG G G PG+TGP+GE G+ G PGR+G PGP Sbjct: 2385 PGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGP 2444 Query: 127 PGVPGMPGP-----------IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEK 175 PG G PG +G PGP G RGE G G G PG GP G G PGSRGE+ Sbjct: 2445 PGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGER 2504 Query: 176 GSRGEKGDLGPKGEKG----FPGFPGMLGQKGEMGPKGEPGIAGHRGP---TGRPGKRGK 228 G +G+ G G KG+KG G PG G KG+MG +G G+ G +GP G PG +G Sbjct: 2505 GEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGS 2564 Query: 229 QGQKGDS---------GVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 +G+ GD G++GP G+PG +G PG PG PG I G KG+ GF GP G Sbjct: 2565 KGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPG-IRGEKGDVGFMGPRG 2623 Score = 175 bits (443), Expect = 9e-44 Identities = 118/293 (40%), Positives = 135/293 (46%), Gaps = 64/293 (21%) Query: 28 PSLDQKKRGGHKACCLLT------PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQS 81 PSLDQ G A C + P P P++ P +G P L ++ Sbjct: 1220 PSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKG------EPGEMGLRGQVGPPGD 1273 Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P G G G PGPQGPPG G +G G GRPG GR G PG PG PG G PG Sbjct: 1274 P---GLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGL 1330 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGE---------------------KGSRGE 180 GPRG+ PG RGP G KG PG+ G+ G RG Sbjct: 1331 PGPRGD---------PGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGP 1381 Query: 181 KGDLGPKGEKGFPG--FPGMLGQKGEMGPKGE------------PGIAGHRGPTGRPGKR 226 GD GP+G G PG G G +GE GP G PG+ G GP G G Sbjct: 1382 LGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPP 1441 Query: 227 GKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 GK+G+KGDS G PG PG G PG GP GPP A +GPKG+RGFPGP G Sbjct: 1442 GKKGEKGDS-EDGAPGLPGQPGSPGEQGPRGPPGA----IGPKGDRGFPGPLG 1489 Score = 175 bits (443), Expect = 9e-44 Identities = 96/217 (44%), Positives = 115/217 (52%), Gaps = 17/217 (7%) Query: 79 SQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 S P +G G PGPPGP GP G G+ G KG++G G PG G+ G G+ G PG G Sbjct: 1609 SGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGP 1668 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPG----------------SRGEKGSRGEKG 182 G +G +G+ G+ G G PGS GP G +G PG +GE G RG++G Sbjct: 1669 VGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEG 1728 Query: 183 DLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPG 242 GPKG+ G PG PG G +G GP G G G RGP G G RG G G SG+ G PG Sbjct: 1729 PRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPG 1788 Query: 243 KPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 GPSG G G G P L G +GE+G PGP G Sbjct: 1789 AAGPSGPNGAAGKAGDPGRDGL-PGLRGEQGLPGPSG 1824 Score = 172 bits (435), Expect = 7e-43 Identities = 92/200 (46%), Positives = 109/200 (54%), Gaps = 8/200 (4%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEG 143 + G G G PG +GP GL G+ GP G+ G PG KG PG PG PG GP G G G Sbjct: 1581 LPGDPGPKGDPGDRGPIGLTGRAGPPGDSGP---PGEKGDPGRPGPPGPVGPRGRDGEVG 1637 Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKG 203 +G++G G GLPG G G +G PG RG G +G++GD G G G PG G G +G Sbjct: 1638 EKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRG 1697 Query: 204 EMGPKGEPGIAGHRGP----TGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP 259 E GP G PG GP G PG RG++G +G G G PG PG G G GPPG P Sbjct: 1698 EPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPG-P 1756 Query: 260 PAGQLIMGPKGERGFPGPPG 279 + GP GE+G GPPG Sbjct: 1757 QGDPGVRGPAGEKGDRGPPG 1776 Score = 171 bits (432), Expect = 2e-42 Identities = 101/254 (39%), Positives = 126/254 (49%), Gaps = 61/254 (24%) Query: 86 GSLGSPGPPGP------QGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWP 139 G++G PGPPGP QG PGLPG+ G G+ G GR G G+ G G PG+PG G P Sbjct: 2224 GAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLP 2283 Query: 140 GPEGPRGEKGDLG-----MMGLPGSRGPMGSKG--------YPGSRGEKGSRGEKGDLGP 186 GP GP+GE G G ++GLPG++G G+ G PG++G++G G +G+ G Sbjct: 2284 GPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGE 2343 Query: 187 KGEKGFPGFPGMLGQKGEMGPKG--------------------------------EPGIA 214 G G PG PG GQKG GPKG PG+ Sbjct: 2344 AGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVV 2403 Query: 215 GHRGPTGRPGKRGKQGQKGDSGVMGPPGK---PGPSGQPGRPGPPGPPPAGQLIMGPKGE 271 G G TG G+ G+ G G+ G+ GPPG+ PGP G PG PG GPP G G Sbjct: 2404 GFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPP-------GASGL 2456 Query: 272 RGFPGPPGRCLCGP 285 +G G PG L GP Sbjct: 2457 KGDKGDPGVGLPGP 2470 Score = 170 bits (431), Expect = 2e-42 Identities = 122/321 (38%), Positives = 139/321 (43%), Gaps = 64/321 (19%) Query: 44 LTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPG-- 101 + P P L P G + P+ P K + E +P + G GSPG GP+GPPG Sbjct: 1418 IAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDG-APGLPGQPGSPGEQGPRGPPGAI 1476 Query: 102 -------LPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG---PIGWPGPEG-------- 143 PG G GEKGE G PG G G PGV G PG P G PGP G Sbjct: 1477 GPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEP 1536 Query: 144 ---------------PRGEKGDLGMMG-----------------LPGSRGPMGSKGYPGS 171 P+GEKGD+G G LPG GP G G G Sbjct: 1537 GRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGP 1596 Query: 172 RGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPG---KRGK 228 G G G GD GP GEKG PG PG G G G GE G G GP G PG K G+ Sbjct: 1597 IGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE 1656 Query: 229 QGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFP---GPPGRCL-CG 284 +G +G GV GP G+ G G PG G G P + GPKG+RG P GPPGR + G Sbjct: 1657 RGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSS----GPKGDRGEPGPPGPPGRLVDTG 1712 Query: 285 PTMNVNNPSYGESVYGPSSPR 305 P GP P+ Sbjct: 1713 PGAREKGEPGDRGQEGPRGPK 1733 Score = 167 bits (424), Expect = 1e-41 Identities = 99/220 (45%), Positives = 111/220 (50%), Gaps = 41/220 (18%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW------P 139 G G GPPG +G PG PG GP G +G G G KG GPPG PG+PG G P Sbjct: 1604 GPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAP 1663 Query: 140 GPEGPRGEKGDLG------MMGLPGSRGPMGSKGYPGSRG-------------EKGSRGE 180 G GP GEKGD G G PGS GP G +G PG G EKG G+ Sbjct: 1664 GVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGD 1723 Query: 181 KGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGP 240 +G GP+G KG PG PG G++G G +G PG P G PG RG G+KGD G P Sbjct: 1724 RGQEGPRGPKGDPGLPGAPGERGIEGFRGPPG------PQGDPGVRGPAGEKGDRG---P 1774 Query: 241 PGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 PG G SG G+PG GP GP G G G PGR Sbjct: 1775 PGLDGRSGLDGKPGAAGPS-------GPNGAAGKAGDPGR 1807 Score = 167 bits (424), Expect = 1e-41 Identities = 113/289 (39%), Positives = 131/289 (45%), Gaps = 74/289 (25%) Query: 82 PCMQGSLGSPGP------PGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP 135 P +QG G PGP PGP G PGL G GP+G G G PG G PG G+ G G Sbjct: 2167 PGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGR-GLTGPTGA 2225 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGF 195 +G PGP GP G G G GLPG +G G PG+ G G+ G+ GD G G G PG Sbjct: 2226 VGLPGPPGPSGLVGPQGSPGLPGQ---VGETGKPGAPGRDGASGKDGDRGSPGVPGSPGL 2282 Query: 196 PGMLGQKGEMGPKGEPGIA-------------------------GHRGPTGRPGKRGKQG 230 PG +G KGE GP G PG A G +G G PG RG++G Sbjct: 2283 PGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKG 2342 Query: 231 QKGDSGVMGPPGK------PGPS--------GQPGRPGPPGPPPA-GQLIM--------- 266 + G +G G PG+ PGP G PG PGPPGPP G L + Sbjct: 2343 EAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGV 2402 Query: 267 -------GPKGERGFPGPPG-RCLCGPTMNVNNPSYGESVYGPSSPRVP 307 GP+GE G PGP G R L GP E + GP P P Sbjct: 2403 VGFPGQTGPRGEMGQPGPSGERGLAGPPGR-------EGIPGPLGPPGP 2444 Score = 166 bits (421), Expect = 3e-41 Identities = 98/233 (42%), Positives = 117/233 (50%), Gaps = 41/233 (17%) Query: 85 QGSLGSPGPPGP-------------QGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPG 131 +G G PGPPGP +G PG G+ GP+G KG+ G PG G G G G Sbjct: 1693 KGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRG 1752 Query: 132 MPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP----- 186 PGP G PG GP GEKGD G GL G G G G G G G+ G+ GD G Sbjct: 1753 PPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPG 1812 Query: 187 -KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPG 245 +GE+G PG G G G+ G G+PG+ G G G PG+ G++G+KGDSG G G+ G Sbjct: 1813 LRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDG 1872 Query: 246 PSGQ------------PGRPGPPGPP-------PAGQLIMGPKGERGFPGPPG 279 P G+ PG PGP GPP P G GPKG+RG G G Sbjct: 1873 PKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGG---TGPKGDRGETGSKG 1922 Score = 164 bits (416), Expect = 1e-40 Identities = 105/255 (41%), Positives = 123/255 (48%), Gaps = 33/255 (12%) Query: 54 PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKG 113 PP G P SP + + E +P G+ G G G G PG PG GP G KG Sbjct: 2231 PPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKG 2290 Query: 114 E-----------LGRPGRKGRPGPPG-----VPGMPGPIGWPGPEGPRGEKGDLGMMGLP 157 E +G PG KG G PG + G PG G G GPRGEKG+ G G P Sbjct: 2291 EPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEP 2350 Query: 158 GSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHR 217 G G G KG PG +G KG G +G G G PG PG+ G G G G PG+ G Sbjct: 2351 GDPGEDGQKGAPGPKGFKGDPG----VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFP 2406 Query: 218 GPTGRPGKRGKQGQKGDSGVMGPPGK---PGPSGQPGRPGPPGPPPAGQL---------- 264 G TG G+ G+ G G+ G+ GPPG+ PGP G PG PG GPP A L Sbjct: 2407 GQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVG 2466 Query: 265 IMGPKGERGFPGPPG 279 + GP+GERG PG G Sbjct: 2467 LPGPRGERGEPGIRG 2481 Score = 162 bits (410), Expect = 6e-40 Identities = 106/284 (37%), Positives = 129/284 (45%), Gaps = 48/284 (16%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGM---PGPIGW 138 P +GS G PG G G PGL G GP+G+ G G PG G PG GVPG+ G +G+ Sbjct: 2559 PGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGF 2618 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE------------------ 180 GP G +GE+G G GL G +G G G PG G G +GE Sbjct: 2619 MGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGL 2678 Query: 181 ---------------KGDLGPKGEKGFPG---FPGMLGQKGEMGPKGEPGIAGHRGPTGR 222 KGD G KGE+G PG FPG G G GP G PG G RGP G Sbjct: 2679 IGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGL 2738 Query: 223 PGKRGKQGQKGDS--GVMGPPGKPGPSGQPGRPGPPGP-PPAGQLIMGPKGERGF--PGP 277 G++G++G G+ G G PG PG G+ GRPGP GP G+ + RGF Sbjct: 2739 QGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEM 2798 Query: 278 PGRCLCGPTMNVNN----PSYGESVYGPSSPRVPVIFVVNNQEE 317 C C + PSY G VPV+ V + +EE Sbjct: 2799 SQHCACQGQFIASGSRPLPSYAADTAGSQLHAVPVLRVSHAEEE 2842 Score = 161 bits (408), Expect = 1e-39 Identities = 111/297 (37%), Positives = 134/297 (45%), Gaps = 85/297 (28%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGP------KGEKGELGRPGRKGRPGPPGVPGMPGPIG 137 + G G G PGP GPPGLPGK G G+ GE G PG GR G G G G G Sbjct: 1810 LPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREG 1869 Query: 138 WPGPEGPRGEKGDLGMMGLPGSRGPMG--SKGYPGSRGEKGSRGEKGDLGPKGEKGFPGF 195 GP+G RG G LG G PG GP+G +G+PG G G +G++G+ G KGE+G PG Sbjct: 1870 RDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGE 1929 Query: 196 PGMLGQKGEM---------------------------------------GPKG---EPGI 213 G+ G+ G + GPKG E G Sbjct: 1930 RGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGP 1989 Query: 214 AGHRGPTGRPGKRGKQGQKGDSGVMGPP-------GKPGPS---GQPGRPGPPGPP---- 259 G GP G PG+RG +G +GD G GPP G PGPS G+PG+PG PG P Sbjct: 1990 PGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAG 2049 Query: 260 -------PAGQLIMGPKGER------------GFPGPPGRCLCGPTMNVNNPSYGES 297 P + G KGER G PGPPG GP ++V+ P G S Sbjct: 2050 GVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGP--PGPKVSVDEPGPGLS 2104 Score = 160 bits (405), Expect = 2e-39 Identities = 105/289 (36%), Positives = 120/289 (41%), Gaps = 65/289 (22%) Query: 57 FRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELG 116 FRG P P ++ E P + G G G PG GP G G G G+ G G Sbjct: 1750 FRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDG 1809 Query: 117 RPGRKGR------PGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPG 170 PG +G GPPG+PG PG G PG G GE GD G G G +G G+ G G Sbjct: 1810 LPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREG 1869 Query: 171 SRGEKGSRGEKGDLGPKGEKGFP--------GFPGM------LGQKGEMGPKGEPGIAGH 216 G KG RG G LGP+G G P GFPG+ G +GE G KGE G+ G Sbjct: 1870 RDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGE 1929 Query: 217 RGPTGRPGK------------------------------------RGKQGQKGDSGVMGP 240 RG G PG ++G KGDSG GP Sbjct: 1930 RGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGP 1989 Query: 241 PGKPGPSGQPGR---------PGPPGPPPAGQLIMGPKGERGFPGPPGR 280 PGK GP G PG PGP GPP GP G G G PG+ Sbjct: 1990 PGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGK 2038 Score = 157 bits (396), Expect = 2e-38 Identities = 95/203 (46%), Positives = 108/203 (53%), Gaps = 16/203 (7%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG 140 +P +G G GPPGPQG PG+ GP GEKG+ G PG GR G G PG GP G Sbjct: 1741 APGERGIEGFRGPPGPQGDPGV---RGPAGEKGDRGPPGLDGRSGLDGKPGAAGP---SG 1794 Query: 141 PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLG 200 P G G+ GD G GLPG RG G G G G G GE G G G+ G PG P Sbjct: 1795 PNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDP---- 1850 Query: 201 QKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR--PGPPG- 257 GE G KGE G +G G GR G +G++G G G GPPG PGP G PG+ PG PG Sbjct: 1851 --GEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGG 1908 Query: 258 -PPPAGQLIMGPKGERGFPGPPG 279 P + G KGE+G PG G Sbjct: 1909 TGPKGDRGETGSKGEQGLPGERG 1931 Score = 155 bits (392), Expect = 7e-38 Identities = 94/203 (46%), Positives = 112/203 (55%), Gaps = 41/203 (20%) Query: 108 PKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP------RGEKGDLGMMGLPGSRG 161 PKG+KGE G G +G+ GPPG PG+PG G PGP+GP +GE+G G G PGS G Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311 Query: 162 PMGSKGYPGSRGEKGS------RGEKGDLGPKGEKGFPGFPGML---------GQKGEMG 206 G+ G PG+ G KGS RG+ G+ GP+G KG PG PG + G+KG+ G Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPG 1371 Query: 207 PKGEPGIAGHRGPTGRPGKRGK--------QGQKGDSGVMGPPGKPGPSG-QPGRPGPPG 257 P G PG RGP G PG RG +G KGD G GPPG PG G PG PG PG Sbjct: 1372 PSGPPG---PRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPG-PGEGGIAPGEPGLPG 1427 Query: 258 PPPAGQLIMGPKGERGFPGPPGR 280 P G G +G GPPG+ Sbjct: 1428 LP-------GSPGPQGPVGPPGK 1443 Score = 128 bits (322), Expect = 9e-30 Identities = 73/175 (41%), Positives = 86/175 (49%), Gaps = 11/175 (6%) Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKG 203 P+G+KG+ G MGL G GP G G PG G G +G G KGE+GFPG G G G Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311 Query: 204 EMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGP------SGQPGRPGPPG 257 G G PG G +G G PG RG G++G G G PG PG G PGR G PG Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPG 1371 Query: 258 P--PPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNN---PSYGESVYGPSSPRVP 307 P PP + +G G RG PG PG + G + P GE P P +P Sbjct: 1372 PSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLP 1426 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 187 bits (476), Expect = 1e-47 Identities = 107/220 (48%), Positives = 121/220 (55%), Gaps = 27/220 (12%) Query: 87 SLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGV---PGMPGPIGWPGPEG 143 S+G PG PGP+G PGLPG G G KG +G PG G PG PG PG+PG G PGP G Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGS---RGEKGSRGEKGDLGPKGEKGF-------- 192 P+G G G GLPG GP+G G+PG GEKG G+ G GP G+KG Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191 Query: 193 ---PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSG--------VMGPP 241 PG PG+ GQKG+ G G PG G GP G PG G G +G G + GP Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 242 GKPGPSGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 G PGP G PGRPG PGP PP G KGE+G PG PG Sbjct: 1252 GNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPG 1291 Score = 186 bits (472), Expect = 4e-47 Identities = 109/225 (48%), Positives = 125/225 (55%), Gaps = 30/225 (13%) Query: 85 QGSLGSPGPPGPQGPPG------LPGKTGPKGEKGELGRPGRKGRPGPPGVPGMP---GP 135 +G LGSPG PG G PG LPG GPKGE G + G +G PG PG+PG+P GP Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 136 IGWP--GPEGPRGEKGDLGMMGLPGSRGPMGSKG-------YPGSRGEKGSRGEKGDLGP 186 +G P GP GP GEKG G+ G PG G G KG PG G G+ G GD+G Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679 Query: 187 KGEKGFPGFPGMLGQKGEMGPKGEPGIA--------GHRGPTGRPGKRGKQGQKGDSGVM 238 G+ G PG PG+ G G G G PGI G G G PG G G+ G G Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739 Query: 239 GPPGKPGPSGQPG--RPGPPGPP--PAGQLIMGPKGERGFPGPPG 279 GPPG PGP G+PG PGPPGPP P + +GPKG+RGFPGPPG Sbjct: 740 GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784 Score = 182 bits (461), Expect = 7e-46 Identities = 115/265 (43%), Positives = 128/265 (48%), Gaps = 31/265 (11%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 PP PP P P+ P + + E P L PGPPG +G PG+PG Sbjct: 823 PPGPPGIP--------GPIGQPGLHGIPGEKGDPGPP----GLDVPGPPGERGSPGIPGA 870 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGS 165 GP G G G PG+ G G PG G G +G PGP GP G G G+ GL G G G Sbjct: 871 PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQ 930 Query: 166 KGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGK 225 G PG GEKGS+GE G GP G P P +LG KGE G G PGI G GP G G Sbjct: 931 PGLPGPTGEKGSKGEPGLPGPPG----PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGL 986 Query: 226 RGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG--PPPAGQLIMGPKGERGFPGPPGRCLC 283 G GQ G SG G PG PGP G PG PG PG PP + G G+ GFPGP G Sbjct: 987 PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG---LKGTIGDMGFPGPQG---- 1039 Query: 284 GPTMNVNNPSYGESVYG-PSSPRVP 307 V P V G P SP +P Sbjct: 1040 -----VEGPPGPSGVPGQPGSPGLP 1059 Score = 181 bits (460), Expect = 9e-46 Identities = 110/249 (44%), Positives = 130/249 (52%), Gaps = 26/249 (10%) Query: 84 MQGSLGSPGPPGPQGP----------PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMP 133 +QG G+PG PG GP PG PG G G G++G PG G PG PG+PG+P Sbjct: 636 IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695 Query: 134 GP--------IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL- 184 G IG PGP GP+G G G G PG+ G +G +G PG G G +GE G Sbjct: 696 GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755 Query: 185 -GPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 GP G G PGF G LG KG+ G G PG G G G PG +G G G G MGPPG Sbjct: 756 PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815 Query: 244 PGPSGQPGRPGPPG-PPPAGQL-IMGPKGERGFPGPPGRCLCGPTMNVNNPSYGES---V 298 PG G G PGPPG P P GQ + G GE+G PGPPG + GP +P + + Sbjct: 816 PG-IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI 874 Query: 299 YGPSSPRVP 307 P SP +P Sbjct: 875 GPPGSPGLP 883 Score = 181 bits (460), Expect = 9e-46 Identities = 111/246 (45%), Positives = 130/246 (52%), Gaps = 22/246 (8%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 PP PP FP P G + P L P +G+LG G G GPPG PG+ Sbjct: 738 PPGPPGFPGPKGEPGFALPGPPGPPGL---------PGFKGALGPKGDRGFPGPPGPPGR 788 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDL---GMMGLPGSRGP 162 TG G G G G G+PGP G PG+PG IG GP GP G G + G+ G+PG +G Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQPGLHGIPGEKGD 847 Query: 163 MGSKG--YPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPT 220 G G PG GE+GS G G GP G G PG PG G G G KGE G+ G GP Sbjct: 848 PGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907 Query: 221 GR---PGKRGKQGQKGDSGVMGPPGKPGPSGQ---PGRPGPPGPP-PAGQLIMGPKGERG 273 G PG+ G G KGD G+ G PG PGP+G+ G PG PGPP P ++G KGE+G Sbjct: 908 GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG 967 Query: 274 FPGPPG 279 PG PG Sbjct: 968 EPGLPG 973 Score = 181 bits (460), Expect = 9e-46 Identities = 107/229 (46%), Positives = 122/229 (53%), Gaps = 31/229 (13%) Query: 82 PCMQGSLGSPGPPG--PQGPPGLPGKTGPKGEKGELGRPGRKGRPGP------------- 126 P G G PG PG GPPGLPG +G KG+ G G PG G PGP Sbjct: 1175 PGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQ 1234 Query: 127 --PGVPGMPGPI-----GWPGPEGPRGE---KGDLGMMGLPGSRGPMGSKGYPGSRGEKG 176 PG PG PGP G PGP+GP G G G GLPG+ G G KG PG G G Sbjct: 1235 GPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPG 1294 Query: 177 SRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSG 236 G KGD GP G +G PG PG+ G KG+ G G PG G +GP+G PG G +G+ G G Sbjct: 1295 LPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG 1354 Query: 237 VMGPPGKPGPSGQ----PGRPGPPGPP--PAGQLIMGPKGERGFPGPPG 279 GPPG PGPSGQ G GPPG P P + + GP+G +G PGP G Sbjct: 1355 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1403 Score = 179 bits (453), Expect = 6e-45 Identities = 109/252 (43%), Positives = 128/252 (50%), Gaps = 51/252 (20%) Query: 85 QGSLGSPGPPGPQGP--------------PGLPGKTGPKGEKG---ELGRPGRKGR---P 124 +G G PGPPGP P PG+PG +GPKG +G + G+PG G+ P Sbjct: 943 KGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLP 1002 Query: 125 GPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSR------GPMGSKGYPGSRGEKGSR 178 GPPG G PG G PG GP G KG +G MG PG + GP G G PGS G G + Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062 Query: 179 GEKGD-----------LGPKGEKGFPGFPGMLGQKGEMGPKGEPGI---AGHRGPTGRPG 224 G+KGD GPKGE G PG+PG G KG +G G PG+ G +G G PG Sbjct: 1063 GDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG 1122 Query: 225 KRGKQGQKGDSGVMGPPGKPGPSGQP------GRPGPPGPP-----PAGQLIMGPKGERG 273 G G G G+ GPPG PG G+P G PG PGPP P I GP G++G Sbjct: 1123 FPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKG 1182 Query: 274 FPGPPGRCLCGP 285 PG PG GP Sbjct: 1183 EPGQPGFGNPGP 1194 Score = 178 bits (451), Expect = 1e-44 Identities = 125/333 (37%), Positives = 154/333 (46%), Gaps = 77/333 (23%) Query: 15 SGLLCYSAGCLALPSLDQKK--RG-----------GHKACCLLTPPPPPLFPPPFFRGGR 61 +G+ G + LP L +K RG G ++ PP PP FP RG + Sbjct: 351 TGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGE--RGQK 408 Query: 62 SPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGP----------------PGLPGK 105 P + P + G G+PG PGP GP PG PG Sbjct: 409 GDEGPPG-------ISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGS 461 Query: 106 TGPKGEKGELGRPGRKG----------------RPGPPGVPGMPGPIGWPGPEGPRGEKG 149 G KG +GE G G KG +PG PG+PG PG +G+PG +G +G+ G Sbjct: 462 PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAG 521 Query: 150 DLGMMGLPGSRGPMGSKGYPGSRGEKGS-------RGEKGDLGPKGEKGFPGFPGMLGQ- 201 G GLPG G G+ G+PGS+GE G +G+KG+LG G G PG PG GQ Sbjct: 522 ATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQD 581 Query: 202 --KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPP--GKPGP---------SG 248 G GPKGEPG +G G PG G G G+ G MGPP G PGP +G Sbjct: 582 GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641 Query: 249 QPGRPGPPGPP-PAGQLIMGPKGERGFPGPPGR 280 PG+PG PGP GQ I P G+ G PG PGR Sbjct: 642 NPGQPGIPGPKGDPGQTITQP-GKPGLPGNPGR 673 Score = 178 bits (451), Expect = 1e-44 Identities = 107/245 (43%), Positives = 125/245 (51%), Gaps = 28/245 (11%) Query: 81 SPCMQGSLGSP---GPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIG 137 +P + G G P G PG QGPPG PG GP E G G PG +G PG PG+PG GP G Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE-GPKGNPGPQGPPGRPGLPGPEGPPG 1273 Query: 138 WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPG 197 PG G +GEKG+ G GLPG G G +G PG +G G G G G G G PGFPG Sbjct: 1274 LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1333 Query: 198 MLGQK---GEMGPKGEPGIAGHRGPTGRPGKRGK----QGQKGDSGVMGPP---GKPGPS 247 M G G GP+GEPG+ G GP G PG G+ +G G G+ G P G PGP Sbjct: 1334 MKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ 1393 Query: 248 GQPGRPGPPGPP--------PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVY 299 G G PGP GPP P G KG+ G PG PG T ++ P + + Sbjct: 1394 GPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPG------TRGLDGPPGPDGLQ 1447 Query: 300 GPSSP 304 GP P Sbjct: 1448 GPPGP 1452 Score = 177 bits (450), Expect = 1e-44 Identities = 108/259 (41%), Positives = 127/259 (49%), Gaps = 46/259 (17%) Query: 60 GRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTG------PKGEKG 113 G SP D + E P ++G G PG PGP+GPPG G+ G P G KG Sbjct: 31 GCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKG 90 Query: 114 ELGRPGRKGRPGPPGVPGMPGPIGWPGPE------GPRGEKGDLGMMGLPGSRGPMGSKG 167 G PG G PG PG+PGMPG G PGP+ G +GE+G G G PG +GP G G Sbjct: 91 IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Query: 168 YPGSRGEKGS------RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTG 221 PG +GE GS G KG+ G G G G PG G G +GP G PG+ G GP G Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 222 RPGKRGK--------QGQKGDSGVMGPPGKPG-------------PSGQPGRPGPPGPPP 260 PG +G +G+KG+ G+ GPPG PG G G PG GPP Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPP- 269 Query: 261 AGQLIMGPKGERGFPGPPG 279 GP G RG PGPPG Sbjct: 270 ------GPPGIRGPPGPPG 282 Score = 177 bits (448), Expect = 2e-44 Identities = 124/345 (35%), Positives = 144/345 (41%), Gaps = 83/345 (24%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGP------------ 93 P P L P G P P E SP G G PGP Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160 Query: 94 ------PGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP------ 141 PGP+G PG PG G +G G G PG G PGPPG+ G PGP G PGP Sbjct: 161 IIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGL 220 Query: 142 --EGPRGEKGDLGMMGLPGSRGPM-------------GSKGYPGSRGEKGSRGEKGDLGP 186 +GP+GEKG+ G+ G PG G + G +G PG RG G G +G GP Sbjct: 221 NFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP 280 Query: 187 ----KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPG 242 KGEKG G PG G+ G+ G G+PGI G G G PG+ G+ G+KG G GPPG Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340 Query: 243 KP----------------------------GPSGQPGRPGPPG-PPPAGQLIMGPKGERG 273 P G G PG GPPG P P G +MGP G G Sbjct: 341 PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG 400 Query: 274 FP---------GPPGRCLCGPTMNVNNPSYG--ESVYGPSSPRVP 307 FP GPPG + GP P GP+ P +P Sbjct: 401 FPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445 Score = 174 bits (442), Expect = 1e-43 Identities = 105/229 (45%), Positives = 119/229 (51%), Gaps = 31/229 (13%) Query: 82 PCMQGSLGSPGP---PGPQGPPGLPGKTGPKGEKGEL-----GRPGRKGRPGPPGVPGMP 133 P QG G PGP PG G PGLPG+ G KG+ G G PG KG PG PG PG P Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094 Query: 134 ------GPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSK---------GYPGSRGEKGSR 178 G G PG G G KG G+ G PG+ GP G K G PG G G Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGG 1154 Query: 179 GEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVM 238 G G GP GEKG PG G+ G G+ G G+PG G+ GP G PG G++G G G+ Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIP 1213 Query: 239 GPPGKPGPSGQ------PGRPGPPGPPPA-GQLIMGPKGERGFPGPPGR 280 G PG PGP G+ PG GPPGPP + G + GPKG G GPPGR Sbjct: 1214 GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR 1262 Score = 174 bits (441), Expect = 1e-43 Identities = 100/223 (44%), Positives = 114/223 (51%), Gaps = 32/223 (14%) Query: 79 SQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 S P ++G G+PGP GP G PGLPG GP G G G G KG PG PG+PG+PG G Sbjct: 1242 SPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD 1301 Query: 139 PGPEGPRGE---------KGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGP--- 186 GP G +G KGD G+ G+PG G G G PGS G +G G G GP Sbjct: 1302 QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1361 Query: 187 ----------KGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSG 236 KG+ G PG PG G KG GP+G G+ G GP G PG+ G G G G Sbjct: 1362 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1421 Query: 237 VMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G PG P GQPG G GPP GP G +G PGPPG Sbjct: 1422 RKGDPGLP---GQPGTRGLDGPP-------GPDGLQGPPGPPG 1454 Score = 172 bits (436), Expect = 6e-43 Identities = 112/264 (42%), Positives = 138/264 (52%), Gaps = 35/264 (13%) Query: 43 LLTPPPPPLFPPPF------FRG--------------GRSPLLSPDMKNLMLELETSQSP 82 L+ PP PP P P F+G G +S + + +E + Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 83 CMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGP------PGVPGMPGPI 136 + G G PGPPG +GPPG PG G KGEKGE G PG++G+PG PG+PG+PG Sbjct: 262 -LPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 G+PG G GEKG G G PG G + + PG+ G +G G G GEKG GFP Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPR--PGTGITIGEKGNIGLPGLPGEKGERGFP 376 Query: 197 GMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPP 256 G+ G G GP G + G GP G PG+RG++G +G G+ PG PG GQPG PG P Sbjct: 377 GIQGPPGLPGPPGA-AVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPGAPGLP 434 Query: 257 GPP-PAGQLIMGPKGERGFPGPPG 279 GPP PAG I P E PGPPG Sbjct: 435 GPPGPAGPHI-PPSDEICEPGPPG 457 Score = 171 bits (433), Expect = 1e-42 Identities = 103/244 (42%), Positives = 117/244 (47%), Gaps = 40/244 (16%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGK 105 PP PP P P G + +P QG G PG PGP+GPPGLPG Sbjct: 1236 PPGPPGSPGPALEGPKG------------------NPGPQGPPGRPGLPGPEGPPGLPGN 1277 Query: 106 TGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGS 165 G KGEKG G+PG G PG G G PG G PG G G KGD G+ G+PG G G Sbjct: 1278 GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGP 1337 Query: 166 KGYPGSRGEKGSRGEKGDLGP-------------KGEKGFPGFPGMLGQKGEMGPKGEPG 212 G PGS G +G G G GP KG+ G PG PG G KG GP+G G Sbjct: 1338 SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1397 Query: 213 IAGHRGPTGRPGKRGKQG------QKGDSGVMGPPGK---PGPSGQPGRPGPPGPPPAGQ 263 + G GP G PG+ G G +KGD G+ G PG GP G G GPPGPP Sbjct: 1398 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS 1457 Query: 264 LIMG 267 + G Sbjct: 1458 VAHG 1461 Score = 169 bits (428), Expect = 5e-42 Identities = 116/302 (38%), Positives = 137/302 (45%), Gaps = 85/302 (28%) Query: 82 PCMQGSLGSPGPPG-----PQGPPGLPGKTGPKGEKGELG-----------RPGRKG--- 122 P +QG G PGPPG P GPPG PG+ G KG++G G +PG G Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435 Query: 123 ----------------RPGPPGVPGMPGPIGWPGPEGPRGEKGDL-------------GM 153 PGPPG PG PG G G +G +G+KGD G Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 154 MGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL------GPKGEKGFPG----------FPG 197 GLPG GP GS G+PG +GEKG G G G G GFPG FPG Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555 Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGD------SGVMGPPGKPGPSGQPG 251 M G KGE+G G PG+ G G G+ G G G KG+ G GPPG PG G PG Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615 Query: 252 RPGPPGPPPAGQLIMGPKGERGF------PGPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 GP GPP G GP GE+G PG PG + GP +P G+++ P P Sbjct: 616 NIGPMGPPGFGP--PGPVGEKGIQGVAGNPGQPG--IPGPK---GDP--GQTITQPGKPG 666 Query: 306 VP 307 +P Sbjct: 667 LP 668 Score = 166 bits (419), Expect = 5e-41 Identities = 112/290 (38%), Positives = 128/290 (44%), Gaps = 69/290 (23%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIG------ 137 + G G PG PG GPPG G G KGEKG+ G G KG PG PG PG PG G Sbjct: 489 ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG 548 Query: 138 ----WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGE---KGDLGPKGEK 190 +PG +G +GE G G GLPG G G G PG G KG G KG+ GP G Sbjct: 549 DILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNP 608 Query: 191 GFPGFPGML--------------------------GQKGEMGPKGEP------------- 211 G PG PG + GQ G GPKG+P Sbjct: 609 GLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLP 668 Query: 212 ---------GIAGHRGPTGRPGKRGKQGQKGDSGV--MGPPGKPGPSGQPGRPGPPGPP- 259 G+ G G G+PG G G KG+ G+ +G PG PGP G PG PGPPG P Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728 Query: 260 -PAGQLIMGPKGERGFPGP---PGRCLCGPTMNVNNPSYGESVYGPSSPR 305 P + GP G GFPGP PG L GP P + + GP R Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF-KGALGPKGDR 777 Score = 165 bits (417), Expect = 9e-41 Identities = 94/207 (45%), Positives = 113/207 (54%), Gaps = 16/207 (7%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEG 143 ++G G G PG +G PGLPG GP+G PG +G+ G G+PG PGP G GP G Sbjct: 43 IKGEKGERGFPGLEGHPGLPGFPGPEGP------PGPRGQKGDDGIPGPPGPKGIRGPPG 96 Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKG 203 G G G+ G+PG G G +G PG G KG RG G G G +G PG PG+ G KG Sbjct: 97 LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156 Query: 204 EMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG-PPPAG 262 E G + G +G G PG G QG G +G+ GP G PGP G G PGPPG P P G Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216 Query: 263 QL---IMGPKGERGF------PGPPGR 280 + GPKGE+G PGPPG+ Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQ 243 Score = 84.3 bits (207), Expect = 2e-16 Identities = 50/116 (43%), Positives = 59/116 (50%), Gaps = 16/116 (13%) Query: 43 LLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGL 102 L+ PP PP P P G+S ++ D + P + G G G PGPQGP GL Sbjct: 1352 LIGPPGPPGLPGP---SGQSIIIKGD----------AGPPGIPGQPGLKGLPGPQGPQGL 1398 Query: 103 PGKTGPKGEKGELGRP---GRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMG 155 PG TGP G+ G G P G GR G PG+PG PG G GP GP G +G G G Sbjct: 1399 PGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 187 bits (476), Expect = 1e-47 Identities = 118/258 (45%), Positives = 130/258 (50%), Gaps = 33/258 (12%) Query: 46 PPPPPLFP----PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPG 101 PP P FP PP G P + L P +G LG G GP GPPG Sbjct: 905 PPGPEGFPGDIGPPGDNGPEGMKGKPGARGL---------PGPRGQLGPEGDEGPMGPPG 955 Query: 102 LPGKTGPKGEKGELGRPGRK---------GRPGPPGVPGMPGPIGWPGPEGPRGEKGDLG 152 PG G G KG GRPG GRPGP G G G IG G G GEKGD G Sbjct: 956 APGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRG 1015 Query: 153 MMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPG 212 MMG PG GP GS G+PG G G+ GE G GP G +G PG G G++G GP G G Sbjct: 1016 MMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAG 1075 Query: 213 IAGHR------GPTGRPGKRGKQGQKGDSGVMGP---PGKPGPSGQPGRPGPPGPP-PAG 262 G R GP GRPG+ G+QG G+ G +G PG PGPSG PG G PG P P G Sbjct: 1076 EQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQG 1135 Query: 263 -QLIMGPKGERGFPGPPG 279 Q +GP GE G GPPG Sbjct: 1136 PQGPIGPPGEMGPKGPPG 1153 Score = 185 bits (469), Expect = 8e-47 Identities = 109/259 (42%), Positives = 132/259 (50%), Gaps = 46/259 (17%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGR------------PGRKGRPGPPGVPGM 132 QGS G GPPGPQG PG PG+ G GE+G LG PG KG PG PG G Sbjct: 1077 QGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGP 1136 Query: 133 PGPIGWPGPEGPRGE---------------KGDLGMMGLPGSRGPMGSKGYPGSRGEKGS 177 GPIG PG GP+G KGDLG +G PG +G +G +G PG G+ G Sbjct: 1137 QGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGP 1196 Query: 178 ------RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQ 231 +G++GD GP GE G G G++ GE GP G PG+ G RGP G+ GK+G++G+ Sbjct: 1197 MGPDGLKGDRGDPGPDGEHGEKGQEGLM---GEDGPPGPPGVTGVRGPEGKSGKQGEKGR 1253 Query: 232 KGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGP---PGRCLCGPTMN 288 G G G G+ G G PG PGPPG P GPKG RG GP PGR Sbjct: 1254 TGAKGAKGYQGQLGEMGVPGDPGPPGTP-------GPKGSRGSLGPTGAPGRMGAQGEPG 1306 Query: 289 VNNPSYGESVYGPSSPRVP 307 + + + GP P P Sbjct: 1307 LAGYDGHKGIVGPLGPPGP 1325 Score = 181 bits (459), Expect = 1e-45 Identities = 123/317 (38%), Positives = 149/317 (47%), Gaps = 53/317 (16%) Query: 2 TGSSFSLAHLLIISGLLCYSAGCLALPSLDQKKRGGHKACCLLTPPP--PPLFPPPFFRG 59 T S +S+ HL AG P L G K C L PP P L P RG Sbjct: 605 TSSGYSIFHL----------AGSTPFPLLMGPP--GPKGDCGLPGPPGLPGLPGIPGARG 652 Query: 60 GRSPLLS---------PDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKG 110 R P P K + S G+ G G PG G PG PG+ G KG Sbjct: 653 PRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKG 712 Query: 111 EKGELGRPGRKGRPGPPGVPG---------MPGPIGWPGPEGPR------------GEKG 149 G G PG +G+PGP G PG +PGP+G PGP+G R G G Sbjct: 713 YPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDG 772 Query: 150 DLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKG 209 + G+ G+PG RG MG G+PG GE+G G G+ G G G PG PG++G G +GP G Sbjct: 773 ERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIG 832 Query: 210 EP---GIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG----PPPAG 262 P G+ G G G PG +G +G++G GV G PG G G G PG PG P P G Sbjct: 833 YPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLG 892 Query: 263 QLIMGPKGERGFPGPPG 279 + +G KG GFPGPPG Sbjct: 893 K--VGDKGSIGFPGPPG 907 Score = 180 bits (456), Expect = 3e-45 Identities = 100/222 (45%), Positives = 123/222 (55%), Gaps = 29/222 (13%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKG---RPGPPGVPGMPGPIGW---- 138 G +G GPPG G PGLPG+ G KG+ G LG PG +G + G PG+ G GP+G Sbjct: 1144 GEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLK 1203 Query: 139 -----PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP 193 PGP+G GEKG G+MG G GP G G G G+ G +GEKG G KG KG+ Sbjct: 1204 GDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQ 1263 Query: 194 GFPGMLGQKGEMGPKGEPGIAGHRG---PTGRPGKRGKQGQKG------DSGVMGPPGKP 244 G G +G G+ GP G PG G RG PTG PG+ G QG+ G G++GP G P Sbjct: 1264 GQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPP 1323 Query: 245 GPSGQPGRPG-------PPGPPPAGQLIMGPKGERGFPGPPG 279 GP G+ G G PPGPP + +G +G+RG PG PG Sbjct: 1324 GPKGEKGEQGEDGKAEGPPGPP-GDRGPVGDRGDRGEPGDPG 1364 Score = 179 bits (455), Expect = 3e-45 Identities = 111/279 (39%), Positives = 136/279 (48%), Gaps = 58/279 (20%) Query: 82 PCMQGSLGSPGPPGPQGP---PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG---- 134 P G G PG PG +G PG PG G +G G G PG G PGPPGVPG+ G Sbjct: 768 PGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGV 827 Query: 135 --PIGWPGPEGPRGEKGDLGMMGL---------------PGSRGPMGSKGYPGSRGEKGS 177 PIG+PGP+G +G G +G GL PG +G GS+G PG G +G Sbjct: 828 LGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGK 887 Query: 178 RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGE---PGIAGHRGPTGRPGKRGKQGQKGD 234 G G +G KG GFPG PG G G++GP G+ G+ G G G PG RG+ G +GD Sbjct: 888 PGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGD 947 Query: 235 SGVMGPPGKPGPSGQPGRPGPPG----------------PPPAGQL-------------I 265 G MGPPG PG GQPGR G PG P P G+ I Sbjct: 948 EGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGI 1007 Query: 266 MGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 +G KG+RG GPPG + GP ++ +P + P P Sbjct: 1008 VGEKGDRGMMGPPG--VPGPKGSMGHPGMPGGMGTPGEP 1044 Score = 176 bits (445), Expect = 5e-44 Identities = 100/220 (45%), Positives = 118/220 (53%), Gaps = 34/220 (15%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGP------KGEKGELGRPGRKGRPGPPGVPGMPGPIG 137 + GS+G PG G +G G+PG +G KG +G G PG +G+PGP G G G IG Sbjct: 842 LMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIG 901 Query: 138 WPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPG 197 +PGP GP G GD+G PG GP G KG PG+RG G RG+ G G +G G PG PG Sbjct: 902 FPGPPGPEGFPGDIGP---PGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPG 958 Query: 198 MLGQKGEMGPKGEPG---IAGHRGPTGRPGKRGKQG---------------QKGDSGVMG 239 + GQ G G G PG + G G GRPG G+QG +KGD G+MG Sbjct: 959 LEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMG 1018 Query: 240 PPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 PPG PGP G G PG PG MG GE G GPPG Sbjct: 1019 PPGVPGPKGSMGHPGMPGG-------MGTPGEPGPQGPPG 1051 Score = 174 bits (441), Expect = 1e-43 Identities = 115/297 (38%), Positives = 143/297 (48%), Gaps = 46/297 (15%) Query: 46 PPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGP--------- 96 P PP P RG P +P E + +G +G GPPGP Sbjct: 1275 PGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGE 1334 Query: 97 ----QGPPGLPGKTGPKGEKGELGRPGR------------KGRPGPPGVPGMPGPIGWPG 140 +GPPG PG GP G++G+ G PG +G+PG G PG PGP GWPG Sbjct: 1335 DGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPG 1394 Query: 141 PEGPR---GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPG 197 P+G + G KG G G PG RG G +G PG RG G +G +G GP G PG G Sbjct: 1395 PKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGP---DGLPGRDG 1451 Query: 198 MLGQKGEMGPKGEP------GIAGHRGPTGRPGKRGKQGQKGDSGV---MGPPGKPGPSG 248 GQ+GE G G+P G G+ G G PG +G G KG+SG+ +GPPGK G G Sbjct: 1452 QAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEG 1511 Query: 249 QPGRPGPPGPPPA-GQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 + G PG G P + GQ G GE GFPG G L GP + + + + GP P Sbjct: 1512 RTGLPGNQGEPGSKGQ--PGDSGEMGFPGMAG--LFGPKGPPGDIGF-KGIQGPRGP 1563 Score = 174 bits (440), Expect = 2e-43 Identities = 93/219 (42%), Positives = 117/219 (53%), Gaps = 23/219 (10%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPG---------MPG 134 ++G G PG PGP G G G G GE G +G G +G GPPGVPG MPG Sbjct: 977 VKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPG 1036 Query: 135 PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPG 194 +G PG GP+G G G G+ G++G G +G G GE+GSRG KG GP+G G PG Sbjct: 1037 GMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPG 1096 Query: 195 FPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPG 254 G+ G++G +G +G PGI G GP G G G+ G +G G +GPPG+ GP G PG G Sbjct: 1097 QQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVG 1156 Query: 255 PPGPP--------------PAGQLIMGPKGERGFPGPPG 279 PG P P Q ++G +GE G G G Sbjct: 1157 EPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSG 1195 Score = 173 bits (438), Expect = 3e-43 Identities = 110/262 (41%), Positives = 130/262 (49%), Gaps = 40/262 (15%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P + G G G G QG PG PG G G G++G G G PGPPG G PG IG PG Sbjct: 861 PGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGD 920 Query: 142 EGPRGEKGDLGMMGLPGSRG---------PMGSKGYPGSRGE---KGSRGEKGDLGPKGE 189 GP G KG G GLPG RG PMG G PG G+ KG G G G KGE Sbjct: 921 NGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGE 980 Query: 190 KGFPGFPGMLGQKGEMG---PKGEPGIAGHRG------PTGRPGKRGKQGQKGDSGVMGP 240 G PG PG +G++G MG GEPGI G +G P G PG +G G G G MG Sbjct: 981 PGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGT 1040 Query: 241 PGKPGPSGQPGRPGPPG-------------PPPAGQL----IMGPKGERGFPGPPG-RCL 282 PG+PGP G PG GPPG PAG+ + GP G +G PG PG + + Sbjct: 1041 PGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGV 1100 Query: 283 CGPTMNVNNPSYGESVYGPSSP 304 G ++ + + + GPS P Sbjct: 1101 AGERGHLGSRGF-PGIPGPSGP 1121 Score = 172 bits (437), Expect = 4e-43 Identities = 95/207 (45%), Positives = 115/207 (55%), Gaps = 22/207 (10%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P +G +G G G GP GLPG+ G G++GE G G G GP G G PG G PG Sbjct: 1426 PGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGA 1485 Query: 142 EGPRGEKGDLGM---MGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 +GP G KG+ G+ +G PG RG G G PG++GE GS+G+ GD GE GFPG G+ Sbjct: 1486 QGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGD---SGEMGFPGMAGL 1542 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR------ 252 G KG P G+ G G +GP G PG GK+G G G++GP G PGP G G Sbjct: 1543 FGPKG---PPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGL 1599 Query: 253 PGPPGPPPAGQLIMGPKGERGFPGPPG 279 GP GPP GP+G G PGPPG Sbjct: 1600 QGPRGPP-------GPRGRPGPPGPPG 1619 Score = 171 bits (434), Expect = 9e-43 Identities = 98/226 (43%), Positives = 112/226 (49%), Gaps = 31/226 (13%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKG------------ELGRPGRKGRPGPPGV 129 P M G +G+PG PGPQGPPG G G +G KG E G G KG PGP G Sbjct: 1032 PGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGR 1091 Query: 130 PGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSR------GEKGD 183 PG PG G G RG G G G+PG GP G+KG PG G +G + GE G Sbjct: 1092 PGRPGQ---QGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148 Query: 184 LGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK 243 GP G G PG PG G KG++GP G PG G G G PG G G G G+ G G Sbjct: 1149 KGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGD 1208 Query: 244 PGPSGQ---------PGRPGPPGPPPAGQLIMGPKGERGFPGPPGR 280 PGP G+ G GPPGPP + GP+G+ G G GR Sbjct: 1209 PGPDGEHGEKGQEGLMGEDGPPGPPGVTG-VRGPEGKSGKQGEKGR 1253 Score = 166 bits (421), Expect = 3e-41 Identities = 107/251 (42%), Positives = 124/251 (49%), Gaps = 39/251 (15%) Query: 69 MKNLMLELETSQSPCMQGSLGSPGPP---GPQGPPGL------PGKTGPKGEKGELGRPG 119 MK + L T + G G PG GP GP GL PG G GEKG+ G G Sbjct: 1166 MKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMG 1225 Query: 120 RKGRPGPPGVPGMPGPIGWPGPEGPRGE---------KGDLGMMGLPGSRGPMGSKGYPG 170 G PGPPGV G+ GP G G +G +G +G LG MG+PG GP G+ G G Sbjct: 1226 EDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKG 1285 Query: 171 SRGEKGSRGEKGDLGPKGEKGFPGF---PGMLGQKGEMGPKGEPGIAGH----RGPTGRP 223 SRG G G G +G +GE G G+ G++G G GPKGE G G GP G P Sbjct: 1286 SRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPP 1345 Query: 224 GKRGKQGQKGDSGVMGPP------------GKPGPSGQPGRPGPPG-PPPAGQL-IMGPK 269 G RG G +GD G G P GKPG GQPG PGP G P P G GPK Sbjct: 1346 GDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPK 1405 Query: 270 GERGFPGPPGR 280 G++G G PGR Sbjct: 1406 GKQGKAGAPGR 1416 Score = 163 bits (412), Expect = 3e-40 Identities = 94/210 (44%), Positives = 108/210 (51%), Gaps = 18/210 (8%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGE---LGRPGRKGRPGPPGVPGMPGPIGWPGPE 142 G +G G G GPPG+PG G G G +G PG G GPPG G PG G G Sbjct: 1006 GIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRR 1065 Query: 143 GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDL------------GPKGEK 190 GPRG G G G G +GP G +G PG G++G GE+G L GP G K Sbjct: 1066 GPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTK 1125 Query: 191 GFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 G PG PG G +G +GP GE G G G G PG G+ G KGD G +G PG+ G GQ Sbjct: 1126 GLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQR 1185 Query: 251 GRPGPPGPP-PAGQLIMGPKGERGFPGPPG 279 G PG G P G G KG+RG PGP G Sbjct: 1186 GEPGLEGDSGPMGP--DGLKGDRGDPGPDG 1213 Score = 163 bits (412), Expect = 3e-40 Identities = 98/241 (40%), Positives = 123/241 (51%), Gaps = 26/241 (10%) Query: 59 GGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRP 118 G P +P K L + +P G+ G PG G G G+ G GP G KGE G Sbjct: 1273 GDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQ 1332 Query: 119 GRKGR-PGPPGVPGMPGPI------------GWPGPEGPRGEKGDLGMMGLPGSRGPMGS 165 G G+ GPPG PG GP+ G+PG EG +G +G G G PG GP G Sbjct: 1333 GEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGW 1392 Query: 166 KGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGK 225 G GS+G +G +G++G G G +G G G+ G +G +G +G GIAG G GR G+ Sbjct: 1393 PGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQ 1452 Query: 226 RGKQGQKGDS---GVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFP---GPPG 279 G+QG++GD G MGP GK G G G PG GPP G KGE G P GPPG Sbjct: 1453 AGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPP-------GFKGESGLPGQLGPPG 1505 Query: 280 R 280 + Sbjct: 1506 K 1506 Score = 161 bits (408), Expect = 1e-39 Identities = 97/224 (43%), Positives = 112/224 (50%), Gaps = 33/224 (14%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEG 143 M G G PGP G G PG+PG G GE G G PG +G PG G G GP GP+G Sbjct: 1016 MMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGP---RGPDG 1072 Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKG------DLGPKGEKGFPGFPG 197 P GE+G G+ G PG +G G G G GE+G G +G GP G KG PG PG Sbjct: 1073 PAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPG 1132 Query: 198 M------LGQKGEMGPKGEP------------GIAGHRGPTGRPGKRGKQGQKGDSGVMG 239 +G GEMGPKG P G+ G GP G PG++G GQ+G+ G+ G Sbjct: 1133 PQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEG 1192 Query: 240 PPGKPGPSGQPGRPGPPGPP----PAGQLIMGPKGERGFPGPPG 279 G GP G G G PGP GQ G GE G PGPPG Sbjct: 1193 DSGPMGPDGLKGDRGDPGPDGEHGEKGQ--EGLMGEDGPPGPPG 1234 Score = 122 bits (305), Expect = 9e-28 Identities = 67/150 (44%), Positives = 84/150 (56%), Gaps = 12/150 (8%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGR---PGRKGRPGPPGVPGMPGPIG 137 +P + G G+ GPPG +G GLPG+ GP G++G GR PG +G PG G PG G +G Sbjct: 1476 NPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMG 1535 Query: 138 WPGPE---GPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPG 194 +PG GP+G GD+G G+ G RGP G G G G G G G GPKG+KG G Sbjct: 1536 FPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRG 1595 Query: 195 FPGMLGQKGEMGPKGEPGIAGHRGPTGRPG 224 G+ G +G GP+G P GP G PG Sbjct: 1596 DWGLQGPRGPPGPRGRP------GPPGPPG 1619 Score = 37.7 bits (86), Expect = 0.021 Identities = 24/58 (41%), Positives = 26/58 (44%), Gaps = 15/58 (25%) Query: 76 LETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMP 133 L S P +G GS G G QGP G PG +GRPGPPG PG P Sbjct: 1579 LGPSGLPGPKGDKGSRGDWGLQGPRGPPGP---------------RGRPGPPGPPGGP 1621 Score = 35.4 bits (80), Expect = 0.11 Identities = 63/266 (23%), Positives = 76/266 (28%), Gaps = 92/266 (34%) Query: 46 PPPPPLFP-PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGP-----PGPQGP 99 PPPP P PP + P+ + + S+ + S P P P Sbjct: 435 PPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPT 494 Query: 100 PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGS 159 PG T P P G P P +P PGS Sbjct: 495 PGSTRSTRPPATMV----PPTSGTSTPRTAPAVP----------------------TPGS 528 Query: 160 RGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGP 219 P GSK GS K + GPK P R P Sbjct: 529 -APTGSKKPIGSEASK----------------------------KAGPKSSP-----RKP 554 Query: 220 TG-RPGKRGKQGQKGDSGVMGPPGKPGPSGQ--------PGR--PGPPGPPPAGQLIM-- 266 RPGK + D P +P PS Q P + P P +G I Sbjct: 555 VPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHL 614 Query: 267 -------------GPKGERGFPGPPG 279 GPKG+ G PGPPG Sbjct: 615 AGSTPFPLLMGPPGPKGDCGLPGPPG 640 >gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] Length = 703 Score = 186 bits (472), Expect = 4e-47 Identities = 105/221 (47%), Positives = 123/221 (55%), Gaps = 24/221 (10%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG- 140 P G G PGP G +GP G+PG G +GE GE G PG +G G G PG+PG G PG Sbjct: 312 PTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGR 371 Query: 141 --PEGPRGEKGDLGMMGLPGSRGPMGSKGY------PGSRGEKGSRGEKGDLGPKGEKGF 192 P GP+GE G G G+PG RG G G PG RG G+ G G GPKGE GF Sbjct: 372 RGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGF 431 Query: 193 ------PGFPGMLGQKGEMGPKGEPG------IAGHRGPTGRPGKRGKQGQKGDSGVMGP 240 PG G LGQKG++G G+PG I G +GP G G +G G KG+ G+ GP Sbjct: 432 TGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGP 491 Query: 241 PGKPGPSGQPGRPGPPGPP--PAGQLIMGPKGERGFPGPPG 279 PG+ G +G+PG GP GPP P I GP G G PGPPG Sbjct: 492 PGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPG 531 Score = 183 bits (464), Expect = 3e-46 Identities = 132/347 (38%), Positives = 156/347 (44%), Gaps = 58/347 (16%) Query: 1 MTGSSFSLAHLLIISGLLCYSAGCLALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGG 60 M G+ L+ LL++ +L G A G+ + P PPF R G Sbjct: 1 MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPF-REG 59 Query: 61 RSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGP-----KGEKGEL 115 + L + L ++L+ P G PGP GP GPPG PGK G G+ G Sbjct: 60 KGQYLEMPLPLLPMDLKGEPGPP-----GKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPA 114 Query: 116 GRPG--RKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMG--------------LPGS 159 G PG R G+ GPPG+PG GP G PG G G +GD G+ G +PG Sbjct: 115 GPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGK 174 Query: 160 RGPMGSKGYPGSRGEKGSRGEKGDLGPKGEK-----GFPGFPGMLGQKGEMGPKGEPGIA 214 G G G PG +GE G +GE G G +G K G PG PG GQ G GP G PG A Sbjct: 175 PGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPA 234 Query: 215 GHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-------------PA 261 G G+PG G G GD G GPPG PGP G+PG GP GPP P Sbjct: 235 G----LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPG 290 Query: 262 GQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYG-ESVYGPSSPRVP 307 Q G KGE G GPPG L GPT YG + GP R P Sbjct: 291 PQGPSGAKGEPGTRGPPG--LIGPT------GYGMPGLPGPKGDRGP 329 Score = 175 bits (444), Expect = 7e-44 Identities = 111/264 (42%), Positives = 133/264 (50%), Gaps = 34/264 (12%) Query: 46 PPPPPLFP------PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGP 99 PP PP FP P G P P + + P + G +G PG PG +G Sbjct: 90 PPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRM----GKAGPPGLPGKVGPPGQPGLRGE 145 Query: 100 PGLPGKTGPKGEKGELG-----------RPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEK 148 PG+ G G +G G G +PG +G PGPPG G PGP G PGP G RG K Sbjct: 146 PGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLK 205 Query: 149 GD--LGMMGLPGSRGPMGSKGYPG-----SRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 GD +G GLPG+ G G+ G PG G+ G G G G KGE G PG PG G+ Sbjct: 206 GDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGE 265 Query: 202 KGEMGPKGEPGI--AGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPS--GQPGRPGPPG 257 G +GPKG PG+ G G G PG +G G KG+ G GPPG GP+ G PG PGP G Sbjct: 266 PGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKG 325 Query: 258 P-PPAG-QLIMGPKGERGFPGPPG 279 PAG ++G +GE G G PG Sbjct: 326 DRGPAGVPGLLGDRGEPGEDGEPG 349 Score = 81.3 bits (199), Expect = 2e-15 Identities = 54/138 (39%), Positives = 62/138 (44%), Gaps = 26/138 (18%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPG------------------- 125 +G LG PG PG +GP G+PG GP G G G PG KG PG Sbjct: 447 KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPT 506 Query: 126 -PPGVPGMPG---PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEK 181 PPGVPG PG P G PGP GP G G G+ G P G G G+ KG + + Sbjct: 507 GPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKPQF 564 Query: 182 GDLGPKGEKGFPGFPGML 199 G LG P F +L Sbjct: 565 G-LGELSAHATPAFTAVL 581 Score = 56.6 bits (135), Expect = 4e-08 Identities = 34/78 (43%), Positives = 36/78 (46%), Gaps = 8/78 (10%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P +G G PG GP GPPG+PG G G PG G PGPPG PG G G Sbjct: 491 PPGEGRAGEPGTAGPTGPPGVPGSPGITGP------PGPPGPPGPPGAPGAFDETGIAGL 544 Query: 142 EGPRG--EKGDLGMMGLP 157 P G E LG G P Sbjct: 545 HLPNGGVEGAVLGKGGKP 562 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 186 bits (472), Expect = 4e-47 Identities = 118/270 (43%), Positives = 131/270 (48%), Gaps = 41/270 (15%) Query: 43 LLTPPPPPLFP-PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLG---SPGPPGPQG 98 LL P PP P PP RG P Q P +GSLG PGPPG QG Sbjct: 525 LLGPKGPPGIPGPPGVRGMDGP----------------QGP--KGSLGPQGEPGPPGQQG 566 Query: 99 PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPG 158 PG G GP+G G G G +G+PG PG+PG GP G PG EGP G KG+ G Sbjct: 567 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN------QG 620 Query: 159 SRGPMGSKGYPGSRGEKGS---RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAG 215 GP G GYPG RG KG RG KG G KGE GFPGF G +G KG+ G G PG G Sbjct: 621 PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 680 Query: 216 HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFP 275 GP G G+ G G G G+MG GK G G PG PG GPKG GFP Sbjct: 681 EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR----------QGPKGSLGFP 730 Query: 276 GPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 G PG ++ S GP+ PR Sbjct: 731 GFPGASGEKGARGLSGKSGPRGERGPTGPR 760 Score = 185 bits (469), Expect = 8e-47 Identities = 103/203 (50%), Positives = 118/203 (58%), Gaps = 9/203 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGE---KGELGRPGRKGRPGPPGVPGMPGPIGW--- 138 +G G PGPPGP GP G PG G GE +G G G KG G G G PGPIG Sbjct: 1015 KGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL 1074 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 PGP G +GE GD+G MG PG GP G G G+ G +G G G+LGP GEKG PG G Sbjct: 1075 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1134 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 G +GE G KG G G +G +G+PG+ G G KG +G GP G PGP G PG PGPPG Sbjct: 1135 PGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE 1194 Query: 259 -PPAGQLIMGPKGERGFPGPPGR 280 P GQ G KG+RG G PG+ Sbjct: 1195 GGPRGQ--DGAKGDRGEDGEPGQ 1215 Score = 182 bits (463), Expect = 4e-46 Identities = 101/213 (47%), Positives = 113/213 (53%), Gaps = 15/213 (7%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G GSPGP G GPPG GK GP G G GR G KG G PG G PG G GP GP Sbjct: 1214 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1273 Query: 146 GEKGDLGMMGLPGSRGPMGSKGY------PGSRGEKGSRGEKGDLGPKGEKGFPGFPGML 199 G+ G G+ GLPGS G G G PG G G G +GD G KGEKG PG G++ Sbjct: 1274 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1333 Query: 200 GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP 259 G GE G KG+ G+ G +G G+ G+ G G G G GPPG PGP+G G G GP Sbjct: 1334 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG 1393 Query: 260 PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNP 292 GPKGE+G GPPG GP V P Sbjct: 1394 -------GPKGEKGVQGPPGH--PGPPGEVIQP 1417 Score = 180 bits (456), Expect = 3e-45 Identities = 99/214 (46%), Positives = 114/214 (53%), Gaps = 20/214 (9%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG----- 140 G G PGPPGP G GLPG G +G KG+ G PG G+ GP G+ G PG G PG Sbjct: 854 GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP 913 Query: 141 -------PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP 193 P GP G G G G GS GP+G G PG +G G+ GEKG G KG G Sbjct: 914 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 973 Query: 194 GFPGMLGQKGEMGPKGEPGIAGH---RGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 G G+ G G GP G PG+AG +G G PG++G +G KG+ G GPPG GP GQP Sbjct: 974 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1033 Query: 251 GRPGPPGPP----PAGQL-IMGPKGERGFPGPPG 279 G G G P P G G +G RGF GPPG Sbjct: 1034 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1067 Score = 180 bits (456), Expect = 3e-45 Identities = 98/199 (49%), Positives = 110/199 (55%), Gaps = 13/199 (6%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G GPPGP G GLPG P GEKGE G G G PGPPG G GP G GP+GP Sbjct: 1057 EGTRGFNGPPGPIGLQGLPG---PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1113 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G+LG G G G GS G G G KG RGE+G+ G G+ G PG PG G G+ Sbjct: 1114 PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD 1173 Query: 205 MGPKGEP---GIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPA 261 GPKG P G G GP G G RG+ G KGD G G PG+PG G G GPPGP Sbjct: 1174 DGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP--- 1230 Query: 262 GQLIMGPKGERGFPGPPGR 280 +G +G G PG GR Sbjct: 1231 ----LGKRGPAGSPGSEGR 1245 Score = 179 bits (455), Expect = 3e-45 Identities = 95/204 (46%), Positives = 110/204 (53%), Gaps = 5/204 (2%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG 140 SP ++G G GP GP+GP GL G G G +G G G +G PG PGV G G G PG Sbjct: 420 SPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPG 479 Query: 141 PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD---LGPKGEKGFPGFPG 197 G +G +GD G GLPG G G +G G G +G GE G LGPKG G PG PG Sbjct: 480 LPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPG 539 Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG 257 + G G GPKG G G GP G+ G G QG G G +GP G+ GP G+PG PG PG Sbjct: 540 VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 599 Query: 258 P--PPAGQLIMGPKGERGFPGPPG 279 PP GP G +G GP G Sbjct: 600 SDGPPGHPGKEGPPGTKGNQGPSG 623 Score = 179 bits (454), Expect = 5e-45 Identities = 107/252 (42%), Positives = 128/252 (50%), Gaps = 60/252 (23%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP---------- 135 G +G PG PGPQGPPG G+ G GEKG +G GR G GP G+PG GP Sbjct: 941 GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 1000 Query: 136 --IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP 193 +G PG +G +G KG+ G G PG GP+G G G+ GE G+RG +G G KG++G Sbjct: 1001 GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1060 Query: 194 GF------------PGMLGQKGE---MGPKGEPGIAGHRGPT------------------ 220 GF PG G+KGE +GP G PG G RGP Sbjct: 1061 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1120 Query: 221 GRPGKRGKQGQKGDSGVMGPPGKPGP---------SGQPGRPGPPGPP-PAGQLIMGPKG 270 G PG++G+ G+ G G+ G PG GP SGQPG PGPPGP P G GPKG Sbjct: 1121 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD--DGPKG 1178 Query: 271 ER---GFPGPPG 279 GFPG PG Sbjct: 1179 NPGPVGFPGDPG 1190 Score = 178 bits (451), Expect = 1e-44 Identities = 105/228 (46%), Positives = 119/228 (52%), Gaps = 27/228 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEK---GELGRPGRKGRPGPPGVPGMPGPIGWPGPE 142 G +G PGPPGP+GP G G GP+G G LG PG KG PG G PG+ G G GP Sbjct: 1088 GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1147 Query: 143 GPRGEKGDLGMMGLP---------------GSRGPMGSKGYPGSRGEKGSRGEKGDLGPK 187 G RGEKG+ G G P G+ GP+G G PG GE G RG+ G G + Sbjct: 1148 GERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDR 1207 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQ---GQKGDSGVMGPPGKP 244 GE G PG PG G GE GP PG G RGP G PG G+Q G KGD G +G PGK Sbjct: 1208 GEDGEPGQPGSPGPTGENGP---PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT 1264 Query: 245 GPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNP 292 GP G G G PGP L G G++G PG G+ GP V P Sbjct: 1265 GPVGPAGPAGKPGPDGLRGL-PGSVGQQGRPGATGQ--AGPPGPVGPP 1309 Score = 177 bits (450), Expect = 1e-44 Identities = 98/220 (44%), Positives = 111/220 (50%), Gaps = 26/220 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G+ GP GP GP G PG+ G G G +G PGR G GPPG G G G GP GP Sbjct: 914 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 973 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 G G G +GLPG GP G G G +GE G G+KG G KGE G PG PG +G G+ Sbjct: 974 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1033 Query: 206 GPKGEPGIAGHRGPTGR------------------------PGKRGKQGQKGDSGVMGPP 241 G G G G RGP G PG G++G+ GD G MGPP Sbjct: 1034 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1093 Query: 242 GKPGPSGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 G PGP G G G GP PP G +GP GE+G PG G Sbjct: 1094 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1133 Score = 177 bits (449), Expect = 2e-44 Identities = 110/275 (40%), Positives = 126/275 (45%), Gaps = 80/275 (29%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGP------------------------------------ 108 QG G PG PG GPPG PGK GP Sbjct: 589 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 648 Query: 109 KGEK------------------GELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGD 150 KGEK GE+G PG +G GP G G GP G PGP G GEKG Sbjct: 649 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708 Query: 151 LGMMGLP------GSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 LG+ GLP G +G +G G+PG+ GEKG+RG G GP+GE+G G G G +G Sbjct: 709 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 768 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRP----------- 253 G G G +G GP G PG+RG G +G +G GP G PGP G+ G P Sbjct: 769 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 828 Query: 254 ----GPPGPP----PAGQL-IMGPKGERGFPGPPG 279 GPPGPP P G GP GERG PGPPG Sbjct: 829 QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 863 Score = 177 bits (449), Expect = 2e-44 Identities = 93/200 (46%), Positives = 108/200 (54%), Gaps = 8/200 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 QG G PGPPG GP G G+TGP GE+G G PG G G PG G G G PGP G Sbjct: 829 QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 888 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G+ G G+ G PG RG G+ G PG +G +G G G G GE+G G G +G G Sbjct: 889 PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR 948 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP-----P 259 GP+G PG AG +G PG++G G G GV GP G PGP+G PG G G Sbjct: 949 PGPQGPPGAAGEKGV---PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 1005 Query: 260 PAGQLIMGPKGERGFPGPPG 279 P + G KGE G PGPPG Sbjct: 1006 PGQKGTKGNKGEHGPPGPPG 1025 Score = 175 bits (443), Expect = 9e-44 Identities = 99/215 (46%), Positives = 113/215 (52%), Gaps = 17/215 (7%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPG------MPGP 135 P +G G G PG QG PG+ G G +GEKGE G+PG G PGP G G PGP Sbjct: 1123 PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGP 1182 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGF 195 +G+PG GP GE G G G G RG G G PGS G G G G LG +G G PG Sbjct: 1183 VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1242 Query: 196 PGM---LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 G G KG+ G G PG G GP G GK G G +G G +G G+PG +GQ G Sbjct: 1243 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP 1302 Query: 253 PGPPGPP--PAGQLIMGPKGERGFP------GPPG 279 PGP GPP P + G KGE+G P GPPG Sbjct: 1303 PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1337 Score = 173 bits (438), Expect = 3e-43 Identities = 95/208 (45%), Positives = 113/208 (54%), Gaps = 17/208 (8%) Query: 86 GSLGSPGP------PGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWP 139 G G PGP PGP+GPPG PGK G G G+ G G +G+ GPPG PG+ GP G Sbjct: 788 GERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA 847 Query: 140 GPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGML 199 G GP GE+G G G PG +G G+ G G++G+ G G G GP G +GFPG G+ Sbjct: 848 GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP 907 Query: 200 GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR------P 253 G G G KG G +G GP G PG+R G G G +GPPG+PGP G PG P Sbjct: 908 GTAGGPGLKGNEGPSGPPGPAGSPGER---GAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 964 Query: 254 GPPGP--PPAGQLIMGPKGERGFPGPPG 279 G GP P + GP G G GPPG Sbjct: 965 GEKGPIGPTGRDGVQGPVGLPGPAGPPG 992 Score = 172 bits (435), Expect = 7e-43 Identities = 93/203 (45%), Positives = 110/203 (54%), Gaps = 9/203 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G GP GP G GLPG GP G G G PG G+ G PG PG G +G+ G GP Sbjct: 775 KGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 834 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G +G G G GPMG +G+PG G G +G G G +G KG PG PG G+ G Sbjct: 835 PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGP 894 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK------PGPSGQPGRPGPPGP 258 G +G PG G G G PG +G +G G G G PG+ GP G PGRPGP GP Sbjct: 895 AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP 954 Query: 259 P-PAGQLIMGPKGERGFPGPPGR 280 P AG+ G GE+G GP GR Sbjct: 955 PGAAGE--KGVPGEKGPIGPTGR 975 Score = 171 bits (432), Expect = 2e-42 Identities = 103/250 (41%), Positives = 121/250 (48%), Gaps = 42/250 (16%) Query: 86 GSLGSPGPPGPQGP---------PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPI 136 G G PGPPG G PG PG+ GPKG G G PG G G G+ G GP Sbjct: 692 GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPR 751 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSR---------GPMGSKGYPGSRGEKGSRGEKGDLGPK 187 G GP GPRG++G G G G++ GP G +G PG +G G G KG GP Sbjct: 752 GERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPP 811 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK---P 244 G+ G PG PG G+ G G G PG G GP G G+ G G++G G GPPG+ P Sbjct: 812 GKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLP 871 Query: 245 GPSGQPGRPGPPGPP-------PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGES 297 G +G+ G G PGPP PAG + G GERG PG G GP + N Sbjct: 872 GTAGKEGTKGDPGPPGAPGKDGPAG--LRGFPGERGLPGTAG----GPGLKGNE------ 919 Query: 298 VYGPSSPRVP 307 GPS P P Sbjct: 920 --GPSGPPGP 927 Score = 164 bits (415), Expect = 2e-40 Identities = 103/277 (37%), Positives = 123/277 (44%), Gaps = 60/277 (21%) Query: 89 GSPGPPGPQG---PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVP--------------- 130 G PGP GP G PPG+ G GP G+ GE G PGR G PG G P Sbjct: 313 GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 372 Query: 131 ----------------------------GMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGP 162 G PGP+G+ G GP G+ G G+ G G GP Sbjct: 373 GGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGP 432 Query: 163 MGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGR 222 G +G G G G G +G G G +G PG PG+ G +G G G PG GHRG TG Sbjct: 433 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 492 Query: 223 ---PGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP----PAGQLIM----GPKGE 271 PG G+ G++GD G +GP G PG SG G GP GPP P G M GPKG Sbjct: 493 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 552 Query: 272 ---RGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 +G PGPPG+ T + P +G P+ Sbjct: 553 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 589 Score = 159 bits (403), Expect = 4e-39 Identities = 97/244 (39%), Positives = 116/244 (47%), Gaps = 17/244 (6%) Query: 79 SQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 +Q+ Q L GPPGP G G PG G G G G G G GP G G+ GP Sbjct: 388 AQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP--- 444 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 PG G RG G G G+PG G G +G+ G G G +G +GD G +G G PG G Sbjct: 445 PGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 504 Query: 199 LGQKGEMGPKGEPGIAGHRG---PTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGP 255 G GE+GP+G PG +G RG P G PG G G +G G GP G GP G+PG PG Sbjct: 505 RGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ 564 Query: 256 PGPP-----PAGQLIMGPKGER------GFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 G P P Q +GP GE+ G PG PG P + GPS P Sbjct: 565 QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP 624 Query: 305 RVPV 308 + P+ Sbjct: 625 QGPL 628 Score = 155 bits (392), Expect = 7e-38 Identities = 98/231 (42%), Positives = 117/231 (50%), Gaps = 12/231 (5%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G G PG G +G GLPG G KG +G+ G G G PG G G G IG G G Sbjct: 460 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 519 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM------ 198 G +G LG G PG GP G +G G +G KGS G +G+ GP G++G PG G+ Sbjct: 520 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 579 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 +G GE GP+G+PG+ G G G PG GK+G G G GP G GP G PG G G Sbjct: 580 IGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 639 Query: 259 PPAGQL--IMGPKGERGFPGPPGRC-LCGPTMNVNNP-SYGESVYGPSSPR 305 L G KGE GFPG G + G V P S GE GP P+ Sbjct: 640 DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED--GPEGPK 688 Score = 155 bits (391), Expect = 9e-38 Identities = 100/246 (40%), Positives = 115/246 (46%), Gaps = 22/246 (8%) Query: 45 TPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 +P P PP G R P SP + P G+ G GP GP GP G PG Sbjct: 1218 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG 1277 Query: 105 KTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMG 164 G +G G +G+ GR G G G PG GP G PG G G KG+ G GL G GP Sbjct: 1278 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP-- 1335 Query: 165 SKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPG 224 PG +GEKG RG G G G+KG G P G G +GP G PG+ G GP G G Sbjct: 1336 ----PGEQGEKGDRGLPGPQGSPGQKGEMGIP---GASGPIGPGGPPGLPGPAGPKGAKG 1388 Query: 225 KRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPA------GQLIMG-----PKGERG 273 G G KG+ GV GPPG PGP G+ +P P P G +M P G G Sbjct: 1389 ATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG--G 1446 Query: 274 FPGPPG 279 PG PG Sbjct: 1447 APGSPG 1452 Score = 137 bits (345), Expect = 2e-32 Identities = 94/266 (35%), Positives = 112/266 (42%), Gaps = 81/266 (30%) Query: 99 PPGLPGKTGPKGEKGELGRP----------------GRKGRPGPPGVPGMPGPIGWPGPE 142 PP GP+G KGE G P G G GPPG+ G PGP+G PG Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 342 Query: 143 GPRGEKGDLGMMGLPGS----------------------------------------RGP 162 GP G G G G PG RGP Sbjct: 343 GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGP 402 Query: 163 MGSKGY---------PGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGP------ 207 G GY PGS G KG G+ G GP+G +G G PG G++G G Sbjct: 403 PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGM 462 Query: 208 KGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP-------PP 260 G+PG+ G RG G PG G++G +GD+G G PG PG G+ G G GP P Sbjct: 463 PGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 522 Query: 261 AGQLIMGPKGERGFPGPPG-RCLCGP 285 G ++GPKG G PGPPG R + GP Sbjct: 523 RG--LLGPKGPPGIPGPPGVRGMDGP 546 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 186 bits (472), Expect = 4e-47 Identities = 118/270 (43%), Positives = 131/270 (48%), Gaps = 41/270 (15%) Query: 43 LLTPPPPPLFP-PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLG---SPGPPGPQG 98 LL P PP P PP RG P Q P +GSLG PGPPG QG Sbjct: 504 LLGPKGPPGIPGPPGVRGMDGP----------------QGP--KGSLGPQGEPGPPGQQG 545 Query: 99 PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPG 158 PG G GP+G G G G +G+PG PG+PG GP G PG EGP G KG+ G Sbjct: 546 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN------QG 599 Query: 159 SRGPMGSKGYPGSRGEKGS---RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAG 215 GP G GYPG RG KG RG KG G KGE GFPGF G +G KG+ G G PG G Sbjct: 600 PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 659 Query: 216 HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFP 275 GP G G+ G G G G+MG GK G G PG PG GPKG GFP Sbjct: 660 EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR----------QGPKGSLGFP 709 Query: 276 GPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 G PG ++ S GP+ PR Sbjct: 710 GFPGASGEKGARGLSGKSGPRGERGPTGPR 739 Score = 185 bits (469), Expect = 8e-47 Identities = 103/203 (50%), Positives = 118/203 (58%), Gaps = 9/203 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGE---KGELGRPGRKGRPGPPGVPGMPGPIGW--- 138 +G G PGPPGP GP G PG G GE +G G G KG G G G PGPIG Sbjct: 994 KGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL 1053 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 PGP G +GE GD+G MG PG GP G G G+ G +G G G+LGP GEKG PG G Sbjct: 1054 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1113 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 G +GE G KG G G +G +G+PG+ G G KG +G GP G PGP G PG PGPPG Sbjct: 1114 PGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE 1173 Query: 259 -PPAGQLIMGPKGERGFPGPPGR 280 P GQ G KG+RG G PG+ Sbjct: 1174 GGPRGQ--DGAKGDRGEDGEPGQ 1194 Score = 182 bits (463), Expect = 4e-46 Identities = 101/213 (47%), Positives = 113/213 (53%), Gaps = 15/213 (7%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G GSPGP G GPPG GK GP G G GR G KG G PG G PG G GP GP Sbjct: 1193 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1252 Query: 146 GEKGDLGMMGLPGSRGPMGSKGY------PGSRGEKGSRGEKGDLGPKGEKGFPGFPGML 199 G+ G G+ GLPGS G G G PG G G G +GD G KGEKG PG G++ Sbjct: 1253 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1312 Query: 200 GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP 259 G GE G KG+ G+ G +G G+ G+ G G G G GPPG PGP+G G G GP Sbjct: 1313 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG 1372 Query: 260 PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNP 292 GPKGE+G GPPG GP V P Sbjct: 1373 -------GPKGEKGVQGPPGH--PGPPGEVIQP 1396 Score = 180 bits (456), Expect = 3e-45 Identities = 99/214 (46%), Positives = 114/214 (53%), Gaps = 20/214 (9%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG----- 140 G G PGPPGP G GLPG G +G KG+ G PG G+ GP G+ G PG G PG Sbjct: 833 GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP 892 Query: 141 -------PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP 193 P GP G G G G GS GP+G G PG +G G+ GEKG G KG G Sbjct: 893 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 952 Query: 194 GFPGMLGQKGEMGPKGEPGIAGH---RGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 G G+ G G GP G PG+AG +G G PG++G +G KG+ G GPPG GP GQP Sbjct: 953 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1012 Query: 251 GRPGPPGPP----PAGQL-IMGPKGERGFPGPPG 279 G G G P P G G +G RGF GPPG Sbjct: 1013 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1046 Score = 180 bits (456), Expect = 3e-45 Identities = 98/199 (49%), Positives = 110/199 (55%), Gaps = 13/199 (6%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G GPPGP G GLPG P GEKGE G G G PGPPG G GP G GP+GP Sbjct: 1036 EGTRGFNGPPGPIGLQGLPG---PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1092 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G+LG G G G GS G G G KG RGE+G+ G G+ G PG PG G G+ Sbjct: 1093 PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD 1152 Query: 205 MGPKGEP---GIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPA 261 GPKG P G G GP G G RG+ G KGD G G PG+PG G G GPPGP Sbjct: 1153 DGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP--- 1209 Query: 262 GQLIMGPKGERGFPGPPGR 280 +G +G G PG GR Sbjct: 1210 ----LGKRGPAGSPGSEGR 1224 Score = 179 bits (455), Expect = 3e-45 Identities = 95/204 (46%), Positives = 110/204 (53%), Gaps = 5/204 (2%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG 140 SP ++G G GP GP+GP GL G G G +G G G +G PG PGV G G G PG Sbjct: 399 SPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPG 458 Query: 141 PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD---LGPKGEKGFPGFPG 197 G +G +GD G GLPG G G +G G G +G GE G LGPKG G PG PG Sbjct: 459 LPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPG 518 Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG 257 + G G GPKG G G GP G+ G G QG G G +GP G+ GP G+PG PG PG Sbjct: 519 VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 578 Query: 258 P--PPAGQLIMGPKGERGFPGPPG 279 PP GP G +G GP G Sbjct: 579 SDGPPGHPGKEGPPGTKGNQGPSG 602 Score = 179 bits (454), Expect = 5e-45 Identities = 107/252 (42%), Positives = 128/252 (50%), Gaps = 60/252 (23%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP---------- 135 G +G PG PGPQGPPG G+ G GEKG +G GR G GP G+PG GP Sbjct: 920 GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 979 Query: 136 --IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP 193 +G PG +G +G KG+ G G PG GP+G G G+ GE G+RG +G G KG++G Sbjct: 980 GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039 Query: 194 GF------------PGMLGQKGE---MGPKGEPGIAGHRGPT------------------ 220 GF PG G+KGE +GP G PG G RGP Sbjct: 1040 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1099 Query: 221 GRPGKRGKQGQKGDSGVMGPPGKPGP---------SGQPGRPGPPGPP-PAGQLIMGPKG 270 G PG++G+ G+ G G+ G PG GP SGQPG PGPPGP P G GPKG Sbjct: 1100 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD--DGPKG 1157 Query: 271 ER---GFPGPPG 279 GFPG PG Sbjct: 1158 NPGPVGFPGDPG 1169 Score = 178 bits (451), Expect = 1e-44 Identities = 105/228 (46%), Positives = 119/228 (52%), Gaps = 27/228 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEK---GELGRPGRKGRPGPPGVPGMPGPIGWPGPE 142 G +G PGPPGP+GP G G GP+G G LG PG KG PG G PG+ G G GP Sbjct: 1067 GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1126 Query: 143 GPRGEKGDLGMMGLP---------------GSRGPMGSKGYPGSRGEKGSRGEKGDLGPK 187 G RGEKG+ G G P G+ GP+G G PG GE G RG+ G G + Sbjct: 1127 GERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDR 1186 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQ---GQKGDSGVMGPPGKP 244 GE G PG PG G GE GP PG G RGP G PG G+Q G KGD G +G PGK Sbjct: 1187 GEDGEPGQPGSPGPTGENGP---PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT 1243 Query: 245 GPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNP 292 GP G G G PGP L G G++G PG G+ GP V P Sbjct: 1244 GPVGPAGPAGKPGPDGLRGL-PGSVGQQGRPGATGQ--AGPPGPVGPP 1288 Score = 177 bits (450), Expect = 1e-44 Identities = 98/220 (44%), Positives = 111/220 (50%), Gaps = 26/220 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G+ GP GP GP G PG+ G G G +G PGR G GPPG G G G GP GP Sbjct: 893 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 952 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 G G G +GLPG GP G G G +GE G G+KG G KGE G PG PG +G G+ Sbjct: 953 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1012 Query: 206 GPKGEPGIAGHRGPTGR------------------------PGKRGKQGQKGDSGVMGPP 241 G G G G RGP G PG G++G+ GD G MGPP Sbjct: 1013 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1072 Query: 242 GKPGPSGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 G PGP G G G GP PP G +GP GE+G PG G Sbjct: 1073 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1112 Score = 177 bits (449), Expect = 2e-44 Identities = 110/275 (40%), Positives = 126/275 (45%), Gaps = 80/275 (29%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGP------------------------------------ 108 QG G PG PG GPPG PGK GP Sbjct: 568 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 627 Query: 109 KGEK------------------GELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGD 150 KGEK GE+G PG +G GP G G GP G PGP G GEKG Sbjct: 628 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687 Query: 151 LGMMGLP------GSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 LG+ GLP G +G +G G+PG+ GEKG+RG G GP+GE+G G G G +G Sbjct: 688 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 747 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRP----------- 253 G G G +G GP G PG+RG G +G +G GP G PGP G+ G P Sbjct: 748 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 807 Query: 254 ----GPPGPP----PAGQL-IMGPKGERGFPGPPG 279 GPPGPP P G GP GERG PGPPG Sbjct: 808 QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 842 Score = 177 bits (449), Expect = 2e-44 Identities = 93/200 (46%), Positives = 108/200 (54%), Gaps = 8/200 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 QG G PGPPG GP G G+TGP GE+G G PG G G PG G G G PGP G Sbjct: 808 QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 867 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G+ G G+ G PG RG G+ G PG +G +G G G G GE+G G G +G G Sbjct: 868 PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR 927 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP-----P 259 GP+G PG AG +G PG++G G G GV GP G PGP+G PG G G Sbjct: 928 PGPQGPPGAAGEKGV---PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 984 Query: 260 PAGQLIMGPKGERGFPGPPG 279 P + G KGE G PGPPG Sbjct: 985 PGQKGTKGNKGEHGPPGPPG 1004 Score = 175 bits (443), Expect = 9e-44 Identities = 99/215 (46%), Positives = 113/215 (52%), Gaps = 17/215 (7%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPG------MPGP 135 P +G G G PG QG PG+ G G +GEKGE G+PG G PGP G G PGP Sbjct: 1102 PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGP 1161 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGF 195 +G+PG GP GE G G G G RG G G PGS G G G G LG +G G PG Sbjct: 1162 VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1221 Query: 196 PGM---LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 G G KG+ G G PG G GP G GK G G +G G +G G+PG +GQ G Sbjct: 1222 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP 1281 Query: 253 PGPPGPP--PAGQLIMGPKGERGFP------GPPG 279 PGP GPP P + G KGE+G P GPPG Sbjct: 1282 PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1316 Score = 173 bits (438), Expect = 3e-43 Identities = 95/208 (45%), Positives = 113/208 (54%), Gaps = 17/208 (8%) Query: 86 GSLGSPGP------PGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWP 139 G G PGP PGP+GPPG PGK G G G+ G G +G+ GPPG PG+ GP G Sbjct: 767 GERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA 826 Query: 140 GPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGML 199 G GP GE+G G G PG +G G+ G G++G+ G G G GP G +GFPG G+ Sbjct: 827 GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP 886 Query: 200 GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR------P 253 G G G KG G +G GP G PG+R G G G +GPPG+PGP G PG P Sbjct: 887 GTAGGPGLKGNEGPSGPPGPAGSPGER---GAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 943 Query: 254 GPPGP--PPAGQLIMGPKGERGFPGPPG 279 G GP P + GP G G GPPG Sbjct: 944 GEKGPIGPTGRDGVQGPVGLPGPAGPPG 971 Score = 172 bits (435), Expect = 7e-43 Identities = 93/203 (45%), Positives = 110/203 (54%), Gaps = 9/203 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G GP GP G GLPG GP G G G PG G+ G PG PG G +G+ G GP Sbjct: 754 KGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 813 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G +G G G GPMG +G+PG G G +G G G +G KG PG PG G+ G Sbjct: 814 PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGP 873 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK------PGPSGQPGRPGPPGP 258 G +G PG G G G PG +G +G G G G PG+ GP G PGRPGP GP Sbjct: 874 AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP 933 Query: 259 P-PAGQLIMGPKGERGFPGPPGR 280 P AG+ G GE+G GP GR Sbjct: 934 PGAAGE--KGVPGEKGPIGPTGR 954 Score = 171 bits (432), Expect = 2e-42 Identities = 103/250 (41%), Positives = 121/250 (48%), Gaps = 42/250 (16%) Query: 86 GSLGSPGPPGPQGP---------PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPI 136 G G PGPPG G PG PG+ GPKG G G PG G G G+ G GP Sbjct: 671 GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPR 730 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSR---------GPMGSKGYPGSRGEKGSRGEKGDLGPK 187 G GP GPRG++G G G G++ GP G +G PG +G G G KG GP Sbjct: 731 GERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPP 790 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK---P 244 G+ G PG PG G+ G G G PG G GP G G+ G G++G G GPPG+ P Sbjct: 791 GKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLP 850 Query: 245 GPSGQPGRPGPPGPP-------PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGES 297 G +G+ G G PGPP PAG + G GERG PG G GP + N Sbjct: 851 GTAGKEGTKGDPGPPGAPGKDGPAG--LRGFPGERGLPGTAG----GPGLKGNE------ 898 Query: 298 VYGPSSPRVP 307 GPS P P Sbjct: 899 --GPSGPPGP 906 Score = 164 bits (415), Expect = 2e-40 Identities = 103/277 (37%), Positives = 123/277 (44%), Gaps = 60/277 (21%) Query: 89 GSPGPPGPQG---PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVP--------------- 130 G PGP GP G PPG+ G GP G+ GE G PGR G PG G P Sbjct: 292 GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 351 Query: 131 ----------------------------GMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGP 162 G PGP+G+ G GP G+ G G+ G G GP Sbjct: 352 GGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGP 411 Query: 163 MGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGR 222 G +G G G G G +G G G +G PG PG+ G +G G G PG GHRG TG Sbjct: 412 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 471 Query: 223 ---PGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP----PAGQLIM----GPKGE 271 PG G+ G++GD G +GP G PG SG G GP GPP P G M GPKG Sbjct: 472 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 531 Query: 272 ---RGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 +G PGPPG+ T + P +G P+ Sbjct: 532 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 568 Score = 159 bits (403), Expect = 4e-39 Identities = 97/244 (39%), Positives = 116/244 (47%), Gaps = 17/244 (6%) Query: 79 SQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 +Q+ Q L GPPGP G G PG G G G G G G GP G G+ GP Sbjct: 367 AQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP--- 423 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 PG G RG G G G+PG G G +G+ G G G +G +GD G +G G PG G Sbjct: 424 PGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 483 Query: 199 LGQKGEMGPKGEPGIAGHRG---PTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGP 255 G GE+GP+G PG +G RG P G PG G G +G G GP G GP G+PG PG Sbjct: 484 RGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ 543 Query: 256 PGPP-----PAGQLIMGPKGER------GFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 G P P Q +GP GE+ G PG PG P + GPS P Sbjct: 544 QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP 603 Query: 305 RVPV 308 + P+ Sbjct: 604 QGPL 607 Score = 155 bits (392), Expect = 7e-38 Identities = 98/231 (42%), Positives = 117/231 (50%), Gaps = 12/231 (5%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G G PG G +G GLPG G KG +G+ G G G PG G G G IG G G Sbjct: 439 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 498 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM------ 198 G +G LG G PG GP G +G G +G KGS G +G+ GP G++G PG G+ Sbjct: 499 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 558 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 +G GE GP+G+PG+ G G G PG GK+G G G GP G GP G PG G G Sbjct: 559 IGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 618 Query: 259 PPAGQL--IMGPKGERGFPGPPGRC-LCGPTMNVNNP-SYGESVYGPSSPR 305 L G KGE GFPG G + G V P S GE GP P+ Sbjct: 619 DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED--GPEGPK 667 Score = 155 bits (391), Expect = 9e-38 Identities = 100/246 (40%), Positives = 115/246 (46%), Gaps = 22/246 (8%) Query: 45 TPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 +P P PP G R P SP + P G+ G GP GP GP G PG Sbjct: 1197 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG 1256 Query: 105 KTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMG 164 G +G G +G+ GR G G G PG GP G PG G G KG+ G GL G GP Sbjct: 1257 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP-- 1314 Query: 165 SKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPG 224 PG +GEKG RG G G G+KG G P G G +GP G PG+ G GP G G Sbjct: 1315 ----PGEQGEKGDRGLPGPQGSPGQKGEMGIP---GASGPIGPGGPPGLPGPAGPKGAKG 1367 Query: 225 KRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPA------GQLIMG-----PKGERG 273 G G KG+ GV GPPG PGP G+ +P P P G +M P G G Sbjct: 1368 ATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG--G 1425 Query: 274 FPGPPG 279 PG PG Sbjct: 1426 APGSPG 1431 Score = 136 bits (342), Expect = 4e-32 Identities = 92/258 (35%), Positives = 110/258 (42%), Gaps = 81/258 (31%) Query: 107 GPKGEKGELGRP----------------GRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGD 150 GP+G KGE G P G G GPPG+ G PGP+G PG GP G G Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 329 Query: 151 LGMMGLPGS----------------------------------------RGPMGSKGY-- 168 G G PG RGP G GY Sbjct: 330 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 389 Query: 169 -------PGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGP------KGEPGIAG 215 PGS G KG G+ G GP+G +G G PG G++G G G+PG+ G Sbjct: 390 RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG 449 Query: 216 HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP-------PPAGQLIMGP 268 RG G PG G++G +GD+G G PG PG G+ G G GP P G ++GP Sbjct: 450 DRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG--LLGP 507 Query: 269 KGERGFPGPPG-RCLCGP 285 KG G PGPPG R + GP Sbjct: 508 KGPPGIPGPPGVRGMDGP 525 Score = 31.6 bits (70), Expect = 1.5 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 9/77 (11%) Query: 207 PKGEPGIAGHRGPTGRPGKRGK-QGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLI 265 P+ + R P +P + + Q Q+ S GP G G G P G L+ Sbjct: 236 PQNQQPHRAQRSPQQQPSRLHRPQNQEPQS-----QAAHGPRGLKGEKGEPAVLEPGMLV 290 Query: 266 MG---PKGERGFPGPPG 279 G P+G G GPPG Sbjct: 291 EGPPGPEGPAGLIGPPG 307 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 186 bits (472), Expect = 4e-47 Identities = 118/270 (43%), Positives = 131/270 (48%), Gaps = 41/270 (15%) Query: 43 LLTPPPPPLFP-PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLG---SPGPPGPQG 98 LL P PP P PP RG P Q P +GSLG PGPPG QG Sbjct: 611 LLGPKGPPGIPGPPGVRGMDGP----------------QGP--KGSLGPQGEPGPPGQQG 652 Query: 99 PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPG 158 PG G GP+G G G G +G+PG PG+PG GP G PG EGP G KG+ G Sbjct: 653 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN------QG 706 Query: 159 SRGPMGSKGYPGSRGEKGS---RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAG 215 GP G GYPG RG KG RG KG G KGE GFPGF G +G KG+ G G PG G Sbjct: 707 PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 766 Query: 216 HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFP 275 GP G G+ G G G G+MG GK G G PG PG GPKG GFP Sbjct: 767 EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR----------QGPKGSLGFP 816 Query: 276 GPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 G PG ++ S GP+ PR Sbjct: 817 GFPGASGEKGARGLSGKSGPRGERGPTGPR 846 Score = 185 bits (469), Expect = 8e-47 Identities = 103/203 (50%), Positives = 118/203 (58%), Gaps = 9/203 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGE---KGELGRPGRKGRPGPPGVPGMPGPIGW--- 138 +G G PGPPGP GP G PG G GE +G G G KG G G G PGPIG Sbjct: 1101 KGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL 1160 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 PGP G +GE GD+G MG PG GP G G G+ G +G G G+LGP GEKG PG G Sbjct: 1161 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1220 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 G +GE G KG G G +G +G+PG+ G G KG +G GP G PGP G PG PGPPG Sbjct: 1221 PGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE 1280 Query: 259 -PPAGQLIMGPKGERGFPGPPGR 280 P GQ G KG+RG G PG+ Sbjct: 1281 GGPRGQ--DGAKGDRGEDGEPGQ 1301 Score = 182 bits (463), Expect = 4e-46 Identities = 101/213 (47%), Positives = 113/213 (53%), Gaps = 15/213 (7%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G GSPGP G GPPG GK GP G G GR G KG G PG G PG G GP GP Sbjct: 1300 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1359 Query: 146 GEKGDLGMMGLPGSRGPMGSKGY------PGSRGEKGSRGEKGDLGPKGEKGFPGFPGML 199 G+ G G+ GLPGS G G G PG G G G +GD G KGEKG PG G++ Sbjct: 1360 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1419 Query: 200 GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP 259 G GE G KG+ G+ G +G G+ G+ G G G G GPPG PGP+G G G GP Sbjct: 1420 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG 1479 Query: 260 PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNP 292 GPKGE+G GPPG GP V P Sbjct: 1480 -------GPKGEKGVQGPPGH--PGPPGEVIQP 1503 Score = 180 bits (456), Expect = 3e-45 Identities = 99/214 (46%), Positives = 114/214 (53%), Gaps = 20/214 (9%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG----- 140 G G PGPPGP G GLPG G +G KG+ G PG G+ GP G+ G PG G PG Sbjct: 940 GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP 999 Query: 141 -------PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP 193 P GP G G G G GS GP+G G PG +G G+ GEKG G KG G Sbjct: 1000 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 1059 Query: 194 GFPGMLGQKGEMGPKGEPGIAGH---RGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQP 250 G G+ G G GP G PG+AG +G G PG++G +G KG+ G GPPG GP GQP Sbjct: 1060 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1119 Query: 251 GRPGPPGPP----PAGQL-IMGPKGERGFPGPPG 279 G G G P P G G +G RGF GPPG Sbjct: 1120 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1153 Score = 180 bits (456), Expect = 3e-45 Identities = 98/199 (49%), Positives = 110/199 (55%), Gaps = 13/199 (6%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G GPPGP G GLPG P GEKGE G G G PGPPG G GP G GP+GP Sbjct: 1143 EGTRGFNGPPGPIGLQGLPG---PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1199 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G+LG G G G GS G G G KG RGE+G+ G G+ G PG PG G G+ Sbjct: 1200 PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD 1259 Query: 205 MGPKGEP---GIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPA 261 GPKG P G G GP G G RG+ G KGD G G PG+PG G G GPPGP Sbjct: 1260 DGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP--- 1316 Query: 262 GQLIMGPKGERGFPGPPGR 280 +G +G G PG GR Sbjct: 1317 ----LGKRGPAGSPGSEGR 1331 Score = 179 bits (455), Expect = 3e-45 Identities = 95/204 (46%), Positives = 110/204 (53%), Gaps = 5/204 (2%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG 140 SP ++G G GP GP+GP GL G G G +G G G +G PG PGV G G G PG Sbjct: 506 SPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPG 565 Query: 141 PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGD---LGPKGEKGFPGFPG 197 G +G +GD G GLPG G G +G G G +G GE G LGPKG G PG PG Sbjct: 566 LPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPG 625 Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG 257 + G G GPKG G G GP G+ G G QG G G +GP G+ GP G+PG PG PG Sbjct: 626 VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 685 Query: 258 P--PPAGQLIMGPKGERGFPGPPG 279 PP GP G +G GP G Sbjct: 686 SDGPPGHPGKEGPPGTKGNQGPSG 709 Score = 179 bits (454), Expect = 5e-45 Identities = 107/252 (42%), Positives = 128/252 (50%), Gaps = 60/252 (23%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP---------- 135 G +G PG PGPQGPPG G+ G GEKG +G GR G GP G+PG GP Sbjct: 1027 GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 1086 Query: 136 --IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFP 193 +G PG +G +G KG+ G G PG GP+G G G+ GE G+RG +G G KG++G Sbjct: 1087 GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1146 Query: 194 GF------------PGMLGQKGE---MGPKGEPGIAGHRGPT------------------ 220 GF PG G+KGE +GP G PG G RGP Sbjct: 1147 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1206 Query: 221 GRPGKRGKQGQKGDSGVMGPPGKPGP---------SGQPGRPGPPGPP-PAGQLIMGPKG 270 G PG++G+ G+ G G+ G PG GP SGQPG PGPPGP P G GPKG Sbjct: 1207 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD--DGPKG 1264 Query: 271 ER---GFPGPPG 279 GFPG PG Sbjct: 1265 NPGPVGFPGDPG 1276 Score = 178 bits (451), Expect = 1e-44 Identities = 105/228 (46%), Positives = 119/228 (52%), Gaps = 27/228 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEK---GELGRPGRKGRPGPPGVPGMPGPIGWPGPE 142 G +G PGPPGP+GP G G GP+G G LG PG KG PG G PG+ G G GP Sbjct: 1174 GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1233 Query: 143 GPRGEKGDLGMMGLP---------------GSRGPMGSKGYPGSRGEKGSRGEKGDLGPK 187 G RGEKG+ G G P G+ GP+G G PG GE G RG+ G G + Sbjct: 1234 GERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDR 1293 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQ---GQKGDSGVMGPPGKP 244 GE G PG PG G GE GP PG G RGP G PG G+Q G KGD G +G PGK Sbjct: 1294 GEDGEPGQPGSPGPTGENGP---PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT 1350 Query: 245 GPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNP 292 GP G G G PGP L G G++G PG G+ GP V P Sbjct: 1351 GPVGPAGPAGKPGPDGLRGL-PGSVGQQGRPGATGQ--AGPPGPVGPP 1395 Score = 177 bits (450), Expect = 1e-44 Identities = 98/220 (44%), Positives = 111/220 (50%), Gaps = 26/220 (11%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G+ GP GP GP G PG+ G G G +G PGR G GPPG G G G GP GP Sbjct: 1000 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 1059 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 G G G +GLPG GP G G G +GE G G+KG G KGE G PG PG +G G+ Sbjct: 1060 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1119 Query: 206 GPKGEPGIAGHRGPTGR------------------------PGKRGKQGQKGDSGVMGPP 241 G G G G RGP G PG G++G+ GD G MGPP Sbjct: 1120 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1179 Query: 242 GKPGPSGQPGRPGPPGP--PPAGQLIMGPKGERGFPGPPG 279 G PGP G G G GP PP G +GP GE+G PG G Sbjct: 1180 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1219 Score = 177 bits (449), Expect = 2e-44 Identities = 110/275 (40%), Positives = 126/275 (45%), Gaps = 80/275 (29%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGP------------------------------------ 108 QG G PG PG GPPG PGK GP Sbjct: 675 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 734 Query: 109 KGEK------------------GELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGD 150 KGEK GE+G PG +G GP G G GP G PGP G GEKG Sbjct: 735 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 794 Query: 151 LGMMGLP------GSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 LG+ GLP G +G +G G+PG+ GEKG+RG G GP+GE+G G G G +G Sbjct: 795 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 854 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRP----------- 253 G G G +G GP G PG+RG G +G +G GP G PGP G+ G P Sbjct: 855 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 914 Query: 254 ----GPPGPP----PAGQL-IMGPKGERGFPGPPG 279 GPPGPP P G GP GERG PGPPG Sbjct: 915 QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 949 Score = 177 bits (449), Expect = 2e-44 Identities = 93/200 (46%), Positives = 108/200 (54%), Gaps = 8/200 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 QG G PGPPG GP G G+TGP GE+G G PG G G PG G G G PGP G Sbjct: 915 QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 974 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G+ G G+ G PG RG G+ G PG +G +G G G G GE+G G G +G G Sbjct: 975 PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR 1034 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP-----P 259 GP+G PG AG +G PG++G G G GV GP G PGP+G PG G G Sbjct: 1035 PGPQGPPGAAGEKGV---PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 1091 Query: 260 PAGQLIMGPKGERGFPGPPG 279 P + G KGE G PGPPG Sbjct: 1092 PGQKGTKGNKGEHGPPGPPG 1111 Score = 175 bits (443), Expect = 9e-44 Identities = 99/215 (46%), Positives = 113/215 (52%), Gaps = 17/215 (7%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPG------MPGP 135 P +G G G PG QG PG+ G G +GEKGE G+PG G PGP G G PGP Sbjct: 1209 PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGP 1268 Query: 136 IGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGF 195 +G+PG GP GE G G G G RG G G PGS G G G G LG +G G PG Sbjct: 1269 VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1328 Query: 196 PGM---LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR 252 G G KG+ G G PG G GP G GK G G +G G +G G+PG +GQ G Sbjct: 1329 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP 1388 Query: 253 PGPPGPP--PAGQLIMGPKGERGFP------GPPG 279 PGP GPP P + G KGE+G P GPPG Sbjct: 1389 PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1423 Score = 173 bits (438), Expect = 3e-43 Identities = 95/208 (45%), Positives = 113/208 (54%), Gaps = 17/208 (8%) Query: 86 GSLGSPGP------PGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWP 139 G G PGP PGP+GPPG PGK G G G+ G G +G+ GPPG PG+ GP G Sbjct: 874 GERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA 933 Query: 140 GPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGML 199 G GP GE+G G G PG +G G+ G G++G+ G G G GP G +GFPG G+ Sbjct: 934 GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP 993 Query: 200 GQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR------P 253 G G G KG G +G GP G PG+R G G G +GPPG+PGP G PG P Sbjct: 994 GTAGGPGLKGNEGPSGPPGPAGSPGER---GAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 1050 Query: 254 GPPGP--PPAGQLIMGPKGERGFPGPPG 279 G GP P + GP G G GPPG Sbjct: 1051 GEKGPIGPTGRDGVQGPVGLPGPAGPPG 1078 Score = 172 bits (435), Expect = 7e-43 Identities = 93/203 (45%), Positives = 110/203 (54%), Gaps = 9/203 (4%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G+ G GP GP G GLPG GP G G G PG G+ G PG PG G +G+ G GP Sbjct: 861 KGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 920 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGE 204 G G +G G G GPMG +G+PG G G +G G G +G KG PG PG G+ G Sbjct: 921 PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGP 980 Query: 205 MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK------PGPSGQPGRPGPPGP 258 G +G PG G G G PG +G +G G G G PG+ GP G PGRPGP GP Sbjct: 981 AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP 1040 Query: 259 P-PAGQLIMGPKGERGFPGPPGR 280 P AG+ G GE+G GP GR Sbjct: 1041 PGAAGE--KGVPGEKGPIGPTGR 1061 Score = 171 bits (432), Expect = 2e-42 Identities = 103/250 (41%), Positives = 121/250 (48%), Gaps = 42/250 (16%) Query: 86 GSLGSPGPPGPQGP---------PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPI 136 G G PGPPG G PG PG+ GPKG G G PG G G G+ G GP Sbjct: 778 GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPR 837 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSR---------GPMGSKGYPGSRGEKGSRGEKGDLGPK 187 G GP GPRG++G G G G++ GP G +G PG +G G G KG GP Sbjct: 838 GERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPP 897 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGK---P 244 G+ G PG PG G+ G G G PG G GP G G+ G G++G G GPPG+ P Sbjct: 898 GKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLP 957 Query: 245 GPSGQPGRPGPPGPP-------PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGES 297 G +G+ G G PGPP PAG + G GERG PG G GP + N Sbjct: 958 GTAGKEGTKGDPGPPGAPGKDGPAG--LRGFPGERGLPGTAG----GPGLKGNE------ 1005 Query: 298 VYGPSSPRVP 307 GPS P P Sbjct: 1006 --GPSGPPGP 1013 Score = 164 bits (415), Expect = 2e-40 Identities = 103/277 (37%), Positives = 123/277 (44%), Gaps = 60/277 (21%) Query: 89 GSPGPPGPQG---PPGLPGKTGPKGEKGELGRPGRKGRPGPPGVP--------------- 130 G PGP GP G PPG+ G GP G+ GE G PGR G PG G P Sbjct: 399 GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 458 Query: 131 ----------------------------GMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGP 162 G PGP+G+ G GP G+ G G+ G G GP Sbjct: 459 GGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGP 518 Query: 163 MGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGR 222 G +G G G G G +G G G +G PG PG+ G +G G G PG GHRG TG Sbjct: 519 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 578 Query: 223 ---PGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP----PAGQLIM----GPKGE 271 PG G+ G++GD G +GP G PG SG G GP GPP P G M GPKG Sbjct: 579 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 638 Query: 272 ---RGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPR 305 +G PGPPG+ T + P +G P+ Sbjct: 639 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 675 Score = 159 bits (403), Expect = 4e-39 Identities = 97/244 (39%), Positives = 116/244 (47%), Gaps = 17/244 (6%) Query: 79 SQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 +Q+ Q L GPPGP G G PG G G G G G G GP G G+ GP Sbjct: 474 AQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP--- 530 Query: 139 PGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM 198 PG G RG G G G+PG G G +G+ G G G +G +GD G +G G PG G Sbjct: 531 PGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 590 Query: 199 LGQKGEMGPKGEPGIAGHRG---PTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGP 255 G GE+GP+G PG +G RG P G PG G G +G G GP G GP G+PG PG Sbjct: 591 RGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ 650 Query: 256 PGPP-----PAGQLIMGPKGER------GFPGPPGRCLCGPTMNVNNPSYGESVYGPSSP 304 G P P Q +GP GE+ G PG PG P + GPS P Sbjct: 651 QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP 710 Query: 305 RVPV 308 + P+ Sbjct: 711 QGPL 714 Score = 155 bits (392), Expect = 7e-38 Identities = 98/231 (42%), Positives = 117/231 (50%), Gaps = 12/231 (5%) Query: 85 QGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGP 144 +G G PG G +G GLPG G KG +G+ G G G PG G G G IG G G Sbjct: 546 RGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE 605 Query: 145 RGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGM------ 198 G +G LG G PG GP G +G G +G KGS G +G+ GP G++G PG G+ Sbjct: 606 SGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 665 Query: 199 LGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP 258 +G GE GP+G+PG+ G G G PG GK+G G G GP G GP G PG G G Sbjct: 666 IGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 725 Query: 259 PPAGQL--IMGPKGERGFPGPPGRC-LCGPTMNVNNP-SYGESVYGPSSPR 305 L G KGE GFPG G + G V P S GE GP P+ Sbjct: 726 DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED--GPEGPK 774 Score = 155 bits (391), Expect = 9e-38 Identities = 100/246 (40%), Positives = 115/246 (46%), Gaps = 22/246 (8%) Query: 45 TPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 +P P PP G R P SP + P G+ G GP GP GP G PG Sbjct: 1304 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG 1363 Query: 105 KTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMG 164 G +G G +G+ GR G G G PG GP G PG G G KG+ G GL G GP Sbjct: 1364 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP-- 1421 Query: 165 SKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPG 224 PG +GEKG RG G G G+KG G P G G +GP G PG+ G GP G G Sbjct: 1422 ----PGEQGEKGDRGLPGPQGSPGQKGEMGIP---GASGPIGPGGPPGLPGPAGPKGAKG 1474 Query: 225 KRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPA------GQLIMG-----PKGERG 273 G G KG+ GV GPPG PGP G+ +P P P G +M P G G Sbjct: 1475 ATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG--G 1532 Query: 274 FPGPPG 279 PG PG Sbjct: 1533 APGSPG 1538 Score = 136 bits (342), Expect = 4e-32 Identities = 92/258 (35%), Positives = 110/258 (42%), Gaps = 81/258 (31%) Query: 107 GPKGEKGELGRP----------------GRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGD 150 GP+G KGE G P G G GPPG+ G PGP+G PG GP G G Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 436 Query: 151 LGMMGLPGS----------------------------------------RGPMGSKGY-- 168 G G PG RGP G GY Sbjct: 437 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 496 Query: 169 -------PGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGP------KGEPGIAG 215 PGS G KG G+ G GP+G +G G PG G++G G G+PG+ G Sbjct: 497 RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG 556 Query: 216 HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP-------PPAGQLIMGP 268 RG G PG G++G +GD+G G PG PG G+ G G GP P G ++GP Sbjct: 557 DRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG--LLGP 614 Query: 269 KGERGFPGPPG-RCLCGP 285 KG G PGPPG R + GP Sbjct: 615 KGPPGIPGPPGVRGMDGP 632 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 186 bits (471), Expect = 5e-47 Identities = 102/228 (44%), Positives = 121/228 (53%), Gaps = 11/228 (4%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP 141 P +GS G+ G GP+G PG PG GPKG G G PG +G PG G+PG G G GP Sbjct: 704 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 763 Query: 142 EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQ 201 +G RG+ G+ G G PG G G G G G G+ GEKG++GP G G G G G+ Sbjct: 764 KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE 823 Query: 202 KGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG--PP 259 +GE GP G G AG G G+PG +G+QG+ G G G PG GPSG PG GP G P Sbjct: 824 RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 883 Query: 260 PAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVP 307 + GP G GFPG GR GP + NP GP P P Sbjct: 884 KGARGAQGPPGATGFPGAAGR--VGPPGSNGNP-------GPPGPPGP 922 Score = 184 bits (466), Expect = 2e-46 Identities = 105/252 (41%), Positives = 129/252 (51%), Gaps = 30/252 (11%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGE------LGRPGRKGRPGPPGVPGMPG 134 +P + G+ G PGP GP GP G G GPKG+ GE G G KG PGP G G PG Sbjct: 424 APGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPG 483 Query: 135 PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPK------- 187 P G G G RGE G +G +G PG RG G++G+PG G G +G G+ GP Sbjct: 484 PAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 543 Query: 188 --------GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMG 239 GE G PG G+ G+ G+ GP+G+ G +G G GRPG G QG +G GVMG Sbjct: 544 ANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG 603 Query: 240 PPGKPGPSGQPGRPGPPGPPPAGQL--IMGPKGERGFPGPPGRCLCGPT-----MNVNNP 292 PG G +G+PG+ G G P A L + G GE G GPPG GP P Sbjct: 604 FPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP--AGPAGERGEQGAPGP 661 Query: 293 SYGESVYGPSSP 304 S + + GP P Sbjct: 662 SGFQGLPGPPGP 673 Score = 181 bits (460), Expect = 9e-46 Identities = 103/236 (43%), Positives = 124/236 (52%), Gaps = 17/236 (7%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G+ G PG G GP G PG+ GP G G G G GRPG PG+PG G G PG GP+ Sbjct: 513 GNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQ 572 Query: 146 GEKGDLGMMG---LPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQK 202 G+ G G G PG GP G++G PG G G +G G+ G GEKG PG PG+ + Sbjct: 573 GKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL---R 629 Query: 203 GEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP--P 260 G G GE G AG GP G G+RG+QG G SG G PG PGP G+ G+PG G P Sbjct: 630 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 689 Query: 261 AGQLIMGPKGERGFPG----PPGRCLCGP-----TMNVNNPSYGESVYGPSSPRVP 307 ++GP+GERGFPG P + L GP T + P GP + P Sbjct: 690 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 745 Score = 181 bits (460), Expect = 9e-46 Identities = 104/254 (40%), Positives = 126/254 (49%), Gaps = 29/254 (11%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG 140 +P QG G+PGP GP G G G G +G G G PG GR GPPG G PGP G PG Sbjct: 862 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921 Query: 141 P---EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPG 197 P +GP+G +GD G G G G G G PG +GE G G G GP G +G G G Sbjct: 922 PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG 981 Query: 198 MLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG 257 ++G G+ G +G PG+ G G G+ G G G +G G +GPPG GP+G+PGR G PG Sbjct: 982 IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 1041 Query: 258 P--PPAGQLIMGPKGER---------GFPGPPGR-CLCGPT--------------MNVNN 291 PP G KG+R G PGPPG GPT M + Sbjct: 1042 ADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSG 1101 Query: 292 PSYGESVYGPSSPR 305 P+ + GP PR Sbjct: 1102 PAGARGIQGPQGPR 1115 Score = 180 bits (457), Expect = 2e-45 Identities = 105/230 (45%), Positives = 124/230 (53%), Gaps = 33/230 (14%) Query: 77 ETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPI 136 E +Q P +G G+PG PGP G G PG G G KG G PG G PG PG G PGP Sbjct: 386 EGAQGP--RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQ 443 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRGPMGS------KGYPGSRGEKGSRGEKGD------L 184 G GP GP+G+ G+ G+ G G +GP G +G PG GE+G RG +G+ + Sbjct: 444 GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 503 Query: 185 GPKGEKGFPGFPGMLGQKGEMGPKGEP------GIAGHRGPTGRPGKRGKQGQKGDSGV- 237 GP GE+G PG G GQ G GPKG P G+AG +G G PG+ G+ G G G+ Sbjct: 504 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 563 Query: 238 -----MGPPGKPGPSGQP---GRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 GP GK GPSG P GRPGPPGP A G G GFPGP G Sbjct: 564 GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGA----RGQPGVMGFPGPKG 609 Score = 179 bits (454), Expect = 5e-45 Identities = 96/212 (45%), Positives = 110/212 (51%), Gaps = 25/212 (11%) Query: 86 GSLGSPGPPGPQGPPGL------------------PGKTGPKGEKGELGRPGRKGRPGPP 127 G+ G GPPGP GPPGL PG+ G G KG+ G G G PG P Sbjct: 1011 GASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAP 1070 Query: 128 GVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPK 187 G PG PGP G G +G RGE G G MG G G G +G G RG+KG GE G+ G K Sbjct: 1071 GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK 1130 Query: 188 GEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPS 247 G +GF G G+ G G G +G G AG GP G PG G G+ G +G+ GP G PGP Sbjct: 1131 GHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR 1190 Query: 248 GQPGRPGPPGPPPAGQLIMGPKGERGFPGPPG 279 G+ G GP GPP G G G PGPPG Sbjct: 1191 GRSGETGPAGPP-------GNPGPPGPPGPPG 1215 Score = 179 bits (453), Expect = 6e-45 Identities = 107/234 (45%), Positives = 120/234 (51%), Gaps = 42/234 (17%) Query: 86 GSLGSPGPPGPQGP---PGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP------I 136 G G PGPPGPQG PG+ G GPKG GE G+ G KG PG PG+ G+PG Sbjct: 582 GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAA 641 Query: 137 GWPGPEGPRGEKGDLG------MMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEK 190 G PGP GP GE+G+ G GLPG GP G G PG +G G G G +GP+GE+ Sbjct: 642 GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 701 Query: 191 GF------------------PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKR------ 226 GF PG PG G KG GP G PG G G G PG+R Sbjct: 702 GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 761 Query: 227 GKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-PAGQLIMGPKGERGFPGPPG 279 G +G +GD G GP G PG G G GP GPP PAG G KGE G PGP G Sbjct: 762 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG--ANGEKGEVGPPGPAG 813 Score = 179 bits (453), Expect = 6e-45 Identities = 102/233 (43%), Positives = 122/233 (52%), Gaps = 38/233 (16%) Query: 85 QGSLGSPGPPGPQGPPGLPGK---------TGPKGEKGELGRPGRKGRPGPPGVPGMPGP 135 +G+ G GPPG QGPPGL G GPKG++G++G G +G PG G G+ GP Sbjct: 731 KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP 790 Query: 136 IGWPGPEGPRGEKGDLG---------MMGLPGSRG------------PMGSKGYPGSRGE 174 IG PGP G GEKG++G G PG RG P G+ G PG++GE Sbjct: 791 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850 Query: 175 KGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGD 234 +G G+KGD G G +G G PG G G GPKG G G G TG PG G+ G G Sbjct: 851 QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 910 Query: 235 SGVMGPPGKPGPSGQ---PGRPGPPGPP-----PAGQLIMGPKGERGFPGPPG 279 +G GPPG PGPSG+ G G GPP P Q GP GE+G PG G Sbjct: 911 NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDG 963 Score = 176 bits (447), Expect = 3e-44 Identities = 100/207 (48%), Positives = 113/207 (54%), Gaps = 18/207 (8%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G G PGP GP G PG PG G KGE G G G +G GP G PG PG PGP G Sbjct: 351 GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS---PGPAGAS 407 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 G G G+ G GS G G G PG G +G G +G GP G KG G PG+ G KGE Sbjct: 408 GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ 467 Query: 206 GPKGEPGIAGHR---GPTGRPGKRGKQGQKGDSGVMGPPGK---PGPSGQPGRPGPPGPP 259 GPKGEPG AG + GP G GKRG +G+ G G +GPPG+ PG G PG+ G GP Sbjct: 468 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK 527 Query: 260 -------PAGQLIMGPKGERGFPGPPG 279 P+G + GPKG G PG PG Sbjct: 528 GAPGERGPSG--LAGPKGANGDPGRPG 552 Score = 176 bits (445), Expect = 5e-44 Identities = 98/221 (44%), Positives = 118/221 (53%), Gaps = 26/221 (11%) Query: 82 PCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGR---KGRPGPPGVP-------- 130 P G G PG G G G PG GP GE+GE G PG +G PGPPG P Sbjct: 623 PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 682 Query: 131 -GMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGE 189 G+PG G PG GPRGE+G G G PG++G G +G PG+ G G +G G GP G Sbjct: 683 QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGA 742 Query: 190 KGFPGFPGMLGQKGE---MGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGP 246 +G PG GM G++G GPKG+ G G +GP G P GK G +G +G +GPPG G Sbjct: 743 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP---GKDGGRGLTGPIGPPGPAGA 799 Query: 247 SGQPGRPGPPGP--------PPAGQLIMGPKGERGFPGPPG 279 +G+ G GPPGP P + GP G GF GPPG Sbjct: 800 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 840 Score = 175 bits (443), Expect = 9e-44 Identities = 93/202 (46%), Positives = 108/202 (53%), Gaps = 8/202 (3%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPR 145 G GSPGP GP+G PG G+TGP G G G G+ G GPPG G G G+PG G + Sbjct: 315 GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK 374 Query: 146 GEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM 205 GE G G G G++GP G G PGS G G+ G G G G KG G PG+ G G Sbjct: 375 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 434 Query: 206 GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP------- 258 GP+G PG G GP G G+ G+ G G G GP G+PGP+G G PGP G Sbjct: 435 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 494 Query: 259 -PPAGQLIMGPKGERGFPGPPG 279 P G +GP GERG PG G Sbjct: 495 GEPGGVGPIGPPGERGAPGNRG 516 Score = 175 bits (443), Expect = 9e-44 Identities = 103/231 (44%), Positives = 120/231 (51%), Gaps = 33/231 (14%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPG---VPGMPGPIG 137 +P +G G PGP G GPPG G+ G KGE+GE G+ G G PGP G PG GP G Sbjct: 820 APGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG 879 Query: 138 WPGPEGPRGEKGD---------LGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKG 188 GP+G RG +G G +G PGS G G G PG G+ G +G +GD GP G Sbjct: 880 VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 939 Query: 189 EKGFPGFPGMLGQKGEM------------GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSG 236 G PG G G GE GP G G+AG RG G PG+RG++G G G Sbjct: 940 RAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG 999 Query: 237 VMGPPGK---PGPSGQPGRPGPPGPP----PAGQLIMGPKGERGFPGPPGR 280 G PGK PG SG G PGP GPP PAG+ G +G G GPPGR Sbjct: 1000 PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE--PGREGSPGADGPPGR 1048 Score = 174 bits (442), Expect = 1e-43 Identities = 104/237 (43%), Positives = 121/237 (51%), Gaps = 38/237 (16%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGP---------PGVPG 131 +P G G GP GP+GPPG PGK G GE G+ G+ G +G PGP PG+PG Sbjct: 226 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPG 285 Query: 132 MPGPIGWPGPEGPRGE------KGDLGMMGLPGSRGPMGSKGYP------------GSRG 173 + G G+PG +G +GE KG+ G G GS GPMG +G P G+RG Sbjct: 286 VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 345 Query: 174 EKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKG 233 G G G GP G G PGFPG G KGE GP G G G +GP G PG G G G Sbjct: 346 NDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAG 405 Query: 234 DS---------GVMGPPGKPGPSGQPGRPGPPGPP-PAGQL-IMGPKGERGFPGPPG 279 S G G G PG +G PG PGP GPP P G +GPKG+ G PG G Sbjct: 406 ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAG 462 Score = 174 bits (440), Expect = 2e-43 Identities = 108/249 (43%), Positives = 125/249 (50%), Gaps = 24/249 (9%) Query: 46 PPPPPLFP-PPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPG 104 PP PP P PP G + ++ + +Q MQG +G P GP+GPPG G Sbjct: 163 PPGPPGPPGPPGLGGNFAAQMAGGFDE---KAGGAQLGVMQGPMG---PMGPRGPPGPAG 216 Query: 105 KTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMG 164 GP+G +G G PG G GP G G PGP G PG +G G+ G G G PG +G G Sbjct: 217 APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARG 276 Query: 165 SKGYPGSRGEKGSRGEKGDLGPKGEKGFPGF------PGMLGQKGEMGPKGEPGIAGHRG 218 G PG G KG RG G G KGE G PG PG G G MGP+G PG G G Sbjct: 277 FPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTG 336 Query: 219 PTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP----PAG----QLIMGPKG 270 P G G RG GQ G + GPPG GP+G PG PG PG P G + GP+G Sbjct: 337 PAGAAGARGNDGQPGPA---GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRG 393 Query: 271 ERGFPGPPG 279 E G PG PG Sbjct: 394 EPGTPGSPG 402 Score = 172 bits (436), Expect = 6e-43 Identities = 92/213 (43%), Positives = 109/213 (51%), Gaps = 17/213 (7%) Query: 84 MQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEG 143 + G +G PGP G G G G GP G G G PG +G GPPG G GP G G G Sbjct: 787 LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 846 Query: 144 PRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKG 203 +GE+G+ G G G+ GP G G PG +G G G KG G +G G GFPG G+ G Sbjct: 847 AKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVG 906 Query: 204 EMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP----- 258 G G PG G GP+G+ G +G +G G G G PG GP+G PG G PG Sbjct: 907 PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG 966 Query: 259 ---PP-----AGQL----IMGPKGERGFPGPPG 279 PP AGQ + G +GERGFPG PG Sbjct: 967 AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG 999 Score = 170 bits (430), Expect = 3e-42 Identities = 109/294 (37%), Positives = 132/294 (44%), Gaps = 82/294 (27%) Query: 88 LGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP------ 141 +G GPPGPQGP G G G +G+KGE G PG +GR G PG PG PGP G PGP Sbjct: 116 VGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGL 175 Query: 142 ------------------------------------------EGPRGEKGDLGMMGLPGS 159 GP+G +G+ G G PG Sbjct: 176 GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGV 235 Query: 160 RGPMGSKGYP---------GSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEM----- 205 GPMG +G P G G+ G GE+G GP+G +GFPG PG+ G KG Sbjct: 236 SGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGL 295 Query: 206 -GPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPS---------GQPGRPGP 255 G KGE G G +G +G PG+ G G G G+ G G+ GP+ GQPG GP Sbjct: 296 DGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGP 355 Query: 256 PGPPPAGQLIMGPKGERGFPGPPG-RCLCGPTMNVNNPSYGESVYG-PSSPRVP 307 PGP +GP G GFPG PG + GPT P + G P +P P Sbjct: 356 PGP-------VGPAGGPGFPGAPGAKGEAGPT-GARGPEGAQGPRGEPGTPGSP 401 Score = 165 bits (418), Expect = 7e-41 Identities = 103/257 (40%), Positives = 119/257 (46%), Gaps = 59/257 (22%) Query: 82 PCMQGSLGSPGPPGPQGPP---------------------GLPGKTGPKGEKGELGRPGR 120 P +G G GP G +GPP G PG GP GE G+ G PG Sbjct: 953 PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 1012 Query: 121 ---KGRPGPPGVPGMPGPIGWPGPEGP---------------RGEKGDLGMMGLPGSRGP 162 +G PGP G PG+ GP G PG EG +G++G+ G +G PG+ GP Sbjct: 1013 SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1072 Query: 163 MGS------KGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGH 216 GS G G RGE G++G G GP G +G G G G KGE G GE G+ GH Sbjct: 1073 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1132 Query: 217 RGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR------------PGPPGPP-PAGQ 263 RG TG G G G GD G GP G GP G PG PGP GPP P G+ Sbjct: 1133 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR 1192 Query: 264 L-IMGPKGERGFPGPPG 279 GP G G PGPPG Sbjct: 1193 SGETGPAGPPGNPGPPG 1209 Score = 164 bits (415), Expect = 2e-40 Identities = 90/202 (44%), Positives = 108/202 (53%), Gaps = 7/202 (3%) Query: 81 SPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPG 140 +P +G G GP G G PG PG+ G G +G GRPG G G G G PG G PG Sbjct: 529 APGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPG 588 Query: 141 PEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLG 200 P GP+G +G G+MG PG +G G G G +G G+ G +G G GE G G PG G Sbjct: 589 PPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAG 648 Query: 201 QKGEMGPKGEPGIAGHR---GPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPG 257 GE G +G PG +G + GP G PG+ GK G +G G G PG GP G+ G PG G Sbjct: 649 PAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERG 708 Query: 258 PPPAGQLIMGPKGERGFPGPPG 279 P A G +G RG PG PG Sbjct: 709 SPGA----QGLQGPRGLPGTPG 726 Score = 162 bits (409), Expect = 7e-40 Identities = 106/276 (38%), Positives = 120/276 (43%), Gaps = 73/276 (26%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPG------PPGVPGMPG---PI 136 G GS G PGP GPPG GK GPKG +G+ G PGR G PG PPG G PG P Sbjct: 906 GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPS 965 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 G GP GP+G G G++GLPG RG G G PG GE G +G G G +G G G P Sbjct: 966 GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 1025 Query: 197 GMLGQKGEMGPKGEPGI---------------------------------AGHRGPTGRP 223 G+ G GE G +G PG G GPTG+ Sbjct: 1026 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085 Query: 224 GKRGKQGQKGDSGVMGP------PGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGF--- 274 G RG+ G +G G GP G GP G G G PG G KG RGF Sbjct: 1086 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE-------RGLKGHRGFTGL 1138 Query: 275 ---PGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVP 307 PGPPG PS + GP+ P P Sbjct: 1139 QGLPGPPG------------PSGDQGASGPAGPSGP 1162 Score = 150 bits (378), Expect = 3e-36 Identities = 87/207 (42%), Positives = 101/207 (48%), Gaps = 45/207 (21%) Query: 82 PCMQGSLGSPG---PPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGW 138 P + G G PG PG GPPG G G KG++GE G G G PGPPG PG GP G Sbjct: 1025 PGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGK 1084 Query: 139 PG------------------------PEGPRGEKGDL---GMMGLPGSRGPMGSKGYPGS 171 G P+GPRG+KG+ G GL G RG G +G PG Sbjct: 1085 QGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGP 1144 Query: 172 RGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQ 231 G G +G G GP G +G P G +GP G+ G G GP G PG RG+ G+ Sbjct: 1145 PGPSGDQGASGPAGPSGPRGPP---------GPVGPSGKDGANGIPGPIGPPGPRGRSGE 1195 Query: 232 KGDSGVMGPPGKPGPSGQPGRPGPPGP 258 G + GPPG PGP PG PGPPGP Sbjct: 1196 TGPA---GPPGNPGP---PGPPGPPGP 1216 Score = 142 bits (357), Expect = 8e-34 Identities = 85/191 (44%), Positives = 98/191 (51%), Gaps = 33/191 (17%) Query: 116 GRPGRKGRPGPPG-VPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGE 174 G+PG KG+ G PG + + GP G PGP+GP GE+G G RG G KG PG RG Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGP------RGDRGDKGEKGAPGPRGR 151 Query: 175 KGSRGEKGDLGPKGEKGFPGFPG------------------------MLGQKGEMGPKGE 210 G G G+ GP G G PG PG M G G MGP+G Sbjct: 152 DGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 211 Query: 211 PGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP-PAGQL-IMGP 268 PG AG GP G G G+ G+ G SG MGP G PGP G+PG G G P AG+ GP Sbjct: 212 PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 271 Query: 269 KGERGFPGPPG 279 +G RGFPG PG Sbjct: 272 QGARGFPGTPG 282 Score = 129 bits (323), Expect = 7e-30 Identities = 72/173 (41%), Positives = 88/173 (50%), Gaps = 13/173 (7%) Query: 86 GSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGP---------I 136 G++G+PG PGP G PG G TG +G++GE G G G GP G G+ GP Sbjct: 1062 GAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA 1121 Query: 137 GWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFP 196 G PG G +G +G G+ GLPG GP G +G G G G RG G +GP G+ G G P Sbjct: 1122 GEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP 1181 Query: 197 GMLGQKGEMGPKGEPGIAG---HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGP 246 G +G G G GE G AG + GP G PG G +GP K GP Sbjct: 1182 GPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREK-GP 1233 Score = 94.4 bits (233), Expect = 2e-19 Identities = 66/160 (41%), Positives = 76/160 (47%), Gaps = 28/160 (17%) Query: 165 SKGYPGSRGEKGSRGEKGDL-GPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRP 223 + G PG +G+KG G+ D+ GPKG PG G GE GP+G+ G +G G P Sbjct: 96 ASGQPGPKGQKGEPGDIKDIVGPKGP------PGPQGPAGEQGPRGD---RGDKGEKGAP 146 Query: 224 GKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAG--------------QLIMGPK 269 G RG+ G+ G G GPPG PGP G PG G AG Q MGP Sbjct: 147 GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 206 Query: 270 GERGFPGPPGRCLCGPTMNVNNPSY-GE-SVYGPSSPRVP 307 G RG PGP G GP NP GE V GP PR P Sbjct: 207 GPRGPPGPAG--APGPQGFQGNPGEPGEPGVSGPMGPRGP 244 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.145 0.478 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 30,645,481 Number of Sequences: 37866 Number of extensions: 2488103 Number of successful extensions: 80428 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 472 Number of HSP's successfully gapped in prelim test: 1209 Number of HSP's that attempted gapping in prelim test: 11512 Number of HSP's gapped (non-prelim): 12682 length of query: 445 length of database: 18,247,518 effective HSP length: 105 effective length of query: 340 effective length of database: 14,271,588 effective search space: 4852339920 effective search space used: 4852339920 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.