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Search of human proteins with 16936522
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16936522 wingless-type MMTV integration site family, member
10B precursor [Homo sapiens]
(389 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16936522 wingless-type MMTV integration site family, member 1... 827 0.0
gi|16936520 wingless-type MMTV integration site family, member 1... 517 e-147
gi|16507239 wingless-type MMTV integration site family, member 6... 276 3e-74
gi|17505191 wingless-type MMTV integration site family, member 7... 275 4e-74
gi|17505193 wingless-type MMTV integration site family, member 7... 274 1e-73
gi|17402922 wingless-type MMTV integration site family, member 4... 272 3e-73
gi|14916475 wingless-type MMTV integration site family, member 3... 272 4e-73
gi|13540477 wingless-type MMTV integration site family, member 3... 266 2e-71
gi|4885655 wingless-type MMTV integration site family, member 1 ... 264 1e-70
gi|13518021 wingless-type MMTV integration site family, member 2... 262 3e-70
gi|13518017 wingless-type MMTV integration site family, member 2... 261 8e-70
gi|4507927 wingless-type MMTV integration site family member 2 p... 254 1e-67
gi|40806205 wingless-type MMTV integration site family, member 5... 243 2e-64
gi|14249180 wingless-type MMTV integration site family, member 5... 241 1e-63
gi|17402919 wingless-type MMTV integration site family, member 5... 241 1e-63
gi|17017974 wingless-type MMTV integration site family, member 1... 235 6e-62
gi|17017976 wingless-type MMTV integration site family, member 9... 231 6e-61
gi|17402916 wingless-type MMTV integration site family, member 1... 228 9e-60
gi|17402914 wingless-type MMTV integration site family, member 1... 228 9e-60
gi|15082261 wingless-type MMTV integration site family, member 9... 216 3e-56
gi|110735437 wingless-type MMTV integration site family, member ... 197 1e-50
gi|17505195 wingless-type MMTV integration site family, member 8... 189 4e-48
gi|239752226 PREDICTED: hypothetical protein XP_002348164 [Homo ... 124 1e-28
gi|239756853 PREDICTED: similar to hCG2042405 [Homo sapiens] 39 0.010
gi|239751341 PREDICTED: hypothetical protein XP_002347812 [Homo ... 39 0.010
gi|239745840 PREDICTED: hypothetical protein XP_002343602 [Homo ... 39 0.010
gi|32479521 dishevelled 1 [Homo sapiens] 35 0.15
gi|239756270 PREDICTED: StAR-related lipid transfer (START) doma... 33 0.44
gi|4502907 chymase 1, mast cell preproprotein [Homo sapiens] 32 0.75
gi|93102379 low density lipoprotein-related protein 1B precursor... 32 0.75
>gi|16936522 wingless-type MMTV integration site family, member 10B
precursor [Homo sapiens]
Length = 389
Score = 827 bits (2135), Expect = 0.0
Identities = 389/389 (100%), Positives = 389/389 (100%)
Query: 1 MLEEPRPRPPPSGLAGLLFLALCSRALSNEILGLKLPGEPPLTANTVCLTLSGLSKRQLG 60
MLEEPRPRPPPSGLAGLLFLALCSRALSNEILGLKLPGEPPLTANTVCLTLSGLSKRQLG
Sbjct: 1 MLEEPRPRPPPSGLAGLLFLALCSRALSNEILGLKLPGEPPLTANTVCLTLSGLSKRQLG 60
Query: 61 LCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRGFRESAFS 120
LCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRGFRESAFS
Sbjct: 61 LCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRGFRESAFS 120
Query: 121 FSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFPHSLPSP 180
FSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFPHSLPSP
Sbjct: 121 FSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFPHSLPSP 180
Query: 181 GPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPRDIQARMRIHNNRVGRQVVT 240
GPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPRDIQARMRIHNNRVGRQVVT
Sbjct: 181 GPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPRDIQARMRIHNNRVGRQVVT 240
Query: 241 ENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHNRNSGAFQPRLR 300
ENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHNRNSGAFQPRLR
Sbjct: 241 ENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHNRNSGAFQPRLR 300
Query: 301 PRRLSGELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRLLDGCGSLCCGRGHNVLRQTR 360
PRRLSGELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRLLDGCGSLCCGRGHNVLRQTR
Sbjct: 301 PRRLSGELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRLLDGCGSLCCGRGHNVLRQTR 360
Query: 361 VERCHCRFHWCCYVLCDECKVTEWVNVCK 389
VERCHCRFHWCCYVLCDECKVTEWVNVCK
Sbjct: 361 VERCHCRFHWCCYVLCDECKVTEWVNVCK 389
>gi|16936520 wingless-type MMTV integration site family, member 10A
precursor [Homo sapiens]
Length = 417
Score = 517 bits (1332), Expect = e-147
Identities = 243/404 (60%), Positives = 296/404 (73%), Gaps = 19/404 (4%)
Query: 5 PRPRPPPSGLAGLLFLALCSRALS----NEILGLKLPGEPPLTANTVCLTLSGLSKRQLG 60
P+P+P P+ L FL L + A+ N+IL L+LP EP L ANTVCLTL GLS+RQ+
Sbjct: 14 PQPQPRPALWVLLFFLLLLAAAMPRSAPNDILDLRLPPEPVLNANTVCLTLPGLSRRQME 73
Query: 61 LCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRGFRESAFS 120
+C+R+PDV ASA+QG+ IA+HECQHQ RDQRWNCS+LE ++P+ S I RGFRESAF+
Sbjct: 74 VCVRHPDVAASAIQGIQIAIHECQHQFRDQRWNCSSLETRNKIPYESPIFSRGFRESAFA 133
Query: 121 FSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKL--LQLQALSRGKSFPHSLP 178
+++ AAGV+HAV+ AC+LGKL +CGC G+++ R KL LQL AL RGK H +P
Sbjct: 134 YAIAAAGVVHAVSNACALGKLKACGCDASRRGDEEAFRRKLHRLQLDALQRGKGLSHGVP 193
Query: 179 SPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPRDIQARMRIHNNRVGRQV 238
+ SPG QD+WEWGGC+ DM FGE+FS+DFLDSRE RDI ARMR+HNNRVGRQ
Sbjct: 194 EHPALPTASPGLQDSWEWGGCSPDMGFGERFSKDFLDSREPHRDIHARMRLHNNRVGRQA 253
Query: 239 VTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHNRNSGAFQ-- 296
V EN++RKCKCHGTSGSCQ KTCW+ PEFR VGA LR R RA I HNRN G +
Sbjct: 254 VMENMRRKCKCHGTSGSCQLKTCWQVTPEFRTVGALLRSRFHRATLIRPHNRNGGQLEPG 313
Query: 297 -----------PRLRPRRLSGELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRLLDGCG 345
P R R +LVYFEKSPDFCER+P + S GT GR CNK+S DGCG
Sbjct: 314 PAGAPSPAPGAPGPRRRASPADLVYFEKSPDFCEREPRLDSAGTVGRLCNKSSAGSDGCG 373
Query: 346 SLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
S+CCGRGHN+LRQTR ERCHCRFHWCC+V+C+EC++TEWV+VCK
Sbjct: 374 SMCCGRGHNILRQTRSERCHCRFHWCCFVVCEECRITEWVSVCK 417
>gi|16507239 wingless-type MMTV integration site family, member 6
precursor [Homo sapiens]
Length = 365
Score = 276 bits (705), Expect = 3e-74
Identities = 159/393 (40%), Positives = 208/393 (52%), Gaps = 45/393 (11%)
Query: 9 PPPSGLAGLLFLALCSRALSNEILGLKLPGEPPLTAN--TVCLTLSGLSKRQLGLCLRNP 66
P PS L LL L LC + GL PL + ++C L+ RQ LC P
Sbjct: 4 PLPSRLGLLLLLLLCPAHVG----GLWWAVGSPLVMDPTSICRKARRLAGRQAELCQAEP 59
Query: 67 DVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSA---ILKRGFRESAFSFSM 123
+V A +G + V ECQ Q R +RWNCS+ H A IL++ RE+AF F++
Sbjct: 60 EVVAELARGARLGVRECQFQFRFRRWNCSS--------HSKAFGRILQQDIRETAFVFAI 111
Query: 124 LAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFPHSLPSPG-- 181
AAG HAV ACS+G+L+ CGC RG++ P PG
Sbjct: 112 TAAGASHAVTQACSMGELLQCGC-------------------QAPRGRAPPRPSGLPGTP 152
Query: 182 --PGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSRE--APRDIQARMRIHNNRVGRQ 237
PG + SP WEWGGC D+DFG++ SR F+D+R DI+A +++HNN GR
Sbjct: 153 GPPGPAGSPEGSAAWEWGGCGDDVDFGDEKSRLFMDARHKRGRGDIRALVQLHNNEAGRL 212
Query: 238 VVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHNRNSGAFQP 297
V + + +CKCHG SGSC +TCW+ P FR VGA L ER A + N + A P
Sbjct: 213 AVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMGTN-DGKALLP 271
Query: 298 RLRPRRLSG--ELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRLLDGCGSLCCGRGHNV 355
+R + G +L+Y SPDFC + GSPGTRGRACN ++ L GC LCCGRGH
Sbjct: 272 AVRTLKPPGRADLLYAADSPDFCAPNRRTGSPGTRGRACNSSAPDLSGCDLLCCGRGHRQ 331
Query: 356 LRQTRVERCHCRFHWCCYVLCDECKVTEWVNVC 388
E C CRFHWCC V C C+V + +++C
Sbjct: 332 ESVQLEENCLCRFHWCCVVQCHRCRVRKELSLC 364
>gi|17505191 wingless-type MMTV integration site family, member 7A
precursor [Homo sapiens]
Length = 349
Score = 275 bits (704), Expect = 4e-74
Identities = 132/355 (37%), Positives = 195/355 (54%), Gaps = 44/355 (12%)
Query: 42 LTANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGG 101
L A+ +C + GL+ RQ +C PD +G + + ECQ Q R+ RWNCSAL G
Sbjct: 32 LGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSAL---G 88
Query: 102 RLPHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKL 161
LK G RE+AF+++++AAGV HA+ AC+ G L CGC + G+ R
Sbjct: 89 ERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHR----- 143
Query: 162 LQLQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPR 221
+ W+WGGC+ D+ +G F++ F+D+RE +
Sbjct: 144 -----------------------------DEGWKWGGCSADIRYGIGFAKVFVDAREIKQ 174
Query: 222 DIQARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGR 281
+ + M +HNN GR+++ EN+K +CKCHG SGSC KTCW P+FR +G L+++
Sbjct: 175 NARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNE 234
Query: 282 AIFIDTHNRNSGAFQPRLRPRR-------LSGELVYFEKSPDFCERDPTMGSPGTRGRAC 334
A+ ++ + L+ ++ + +LVY EKSP++CE DP GS GT+GRAC
Sbjct: 235 AVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRAC 294
Query: 335 NKTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
NKT+ GC +CCGRG+N + RV +C+C+FHWCCYV C+ C + CK
Sbjct: 295 NKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK 349
>gi|17505193 wingless-type MMTV integration site family, member 7B
precursor [Homo sapiens]
Length = 349
Score = 274 bits (700), Expect = 1e-73
Identities = 140/356 (39%), Positives = 198/356 (55%), Gaps = 46/356 (12%)
Query: 42 LTANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGG 101
L AN +C + GL+ RQ +C PD +G + ++ECQ+Q R RWNCSAL G
Sbjct: 32 LGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGINECQYQFRFGRWNCSAL---G 88
Query: 102 RLPHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKL 161
L+ G RE+AF++++ AAGV HAV ACS G L +CGC + G ++
Sbjct: 89 EKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQGYYNQAEG-- 146
Query: 162 LQLQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPR 221
W+WGGC+ D+ +G FSR F+D+RE +
Sbjct: 147 --------------------------------WKWGGCSADVRYGIDFSRRFVDAREIKK 174
Query: 222 DIQARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGR 281
+ + M +HNN GR+V+ + ++ +CKCHG SGSC KTCW P+FR VG L+E+
Sbjct: 175 NARRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNA 234
Query: 282 AIFIDTHNRNSGAFQPR-LRPRRLSG-------ELVYFEKSPDFCERDPTMGSPGTRGRA 333
A+ ++ R S QP LR ++L +LVY EKSP++CE D GS GT+GR
Sbjct: 235 AVQVEVV-RASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRL 293
Query: 334 CNKTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
CN+TS DGC ++CCGRG+N + T+V +C+C+FHWCC+V C+ C V CK
Sbjct: 294 CNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK 349
>gi|17402922 wingless-type MMTV integration site family, member 4
precursor [Homo sapiens]
Length = 351
Score = 272 bits (696), Expect = 3e-73
Identities = 147/380 (38%), Positives = 208/380 (54%), Gaps = 47/380 (12%)
Query: 17 LLFLALCSRALSNEILGLKLPGEPPLTANTVCLTLSGLSKRQLGLCLRNPDVTASALQGL 76
LL A+ S A SN + KL ++ C L GL +RQ+ +C RN +V S +G
Sbjct: 12 LLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGA 71
Query: 77 HIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRGFRESAFSFSMLAAGVMHAVATAC 136
+A+ ECQ+Q R++RWNCS L+ LP ++ +G RE+AF +++ +AGV AV AC
Sbjct: 72 QLAIEECQYQFRNRRWNCSTLDS---LPVFGKVVTQGTREAAFVYAISSAGVAFAVTRAC 128
Query: 137 SLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEW 196
S G+L CGC DR H + G ++W
Sbjct: 129 SSGELEKCGC--------DRT----------------VHGVSPQG------------FQW 152
Query: 197 GGCNHDMDFGEKFSRDFLDSREAPRDI---QARMRIHNNRVGRQVVTENLKRKCKCHGTS 253
GC+ ++ +G FS+ F+D RE + +A M +HNN GR+ + +++ +CKCHG S
Sbjct: 153 SGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVS 212
Query: 254 GSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHNRNSG-AFQPR---LRPRRLSGELV 309
GSC+ KTCWRA P FR VG AL+E+ A ++ S A PR +P +LV
Sbjct: 213 GSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRALVPRNAQFKPHT-DEDLV 271
Query: 310 YFEKSPDFCERDPTMGSPGTRGRACNKTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFH 369
Y E SPDFCE+D G GTRGR CNKTS+ +DGC LCCGRG + + ERC C+FH
Sbjct: 272 YLEPSPDFCEQDMRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCSCKFH 331
Query: 370 WCCYVLCDECKVTEWVNVCK 389
WCC+V C +C+ ++ C+
Sbjct: 332 WCCFVKCRQCQRLVELHTCR 351
>gi|14916475 wingless-type MMTV integration site family, member 3A
[Homo sapiens]
Length = 352
Score = 272 bits (695), Expect = 4e-73
Identities = 147/385 (38%), Positives = 203/385 (52%), Gaps = 53/385 (13%)
Query: 19 FLALCS--RALSNEILGLKLPGEPPLTA----NTVCLTLSGLSKRQLGLCLRNPDVTASA 72
FL LCS +AL + + L P ++ +C ++ GL +QL C ++ S
Sbjct: 7 FLLLCSLKQALGSYPIWWSLAVGPQYSSLGSQPILCASIPGLVPKQLRFCRNYVEIMPSV 66
Query: 73 LQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRGFRESAFSFSMLAAGVMHAV 132
+G+ I + ECQHQ R +RWNC+ + L +L + RESAF ++ +AGV AV
Sbjct: 67 AEGIKIGIQECQHQFRGRRWNCTTVHDS--LAIFGPVLDKATRESAFVHAIASAGVAFAV 124
Query: 133 ATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFPHSLPSPGPGSSPSPGPQD 192
+C+ G CGC + G SPG G
Sbjct: 125 TRSCAEGTAAICGCSSRHQG--------------------------SPGKG--------- 149
Query: 193 TWEWGGCNHDMDFGEKFSRDFLDSREAPRDIQARMRIHNNRVGRQVVTENLKRKCKCHGT 252
W+WGGC+ D++FG SR+F D+RE D ++ M HNN GRQ + ++ KCKCHG
Sbjct: 150 -WKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGL 208
Query: 253 SGSCQFKTCWRAAPEFRAVGAALRERLGRA--IFIDTHNRNSGAFQPRLRPRRL------ 304
SGSC+ KTCW + P+FRA+G L+++ A + ++ H R S + LRPR
Sbjct: 209 SGSCEVKTCWWSQPDFRAIGDFLKDKYDSASEMVVEKH-RESRGWVETLRPRYTYFKVPT 267
Query: 305 SGELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRLLDGCGSLCCGRGHNVLRQTRVERC 364
+LVY+E SP+FCE +P GS GTR R CN +S +DGC LCCGRGHN + R E+C
Sbjct: 268 ERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARAERRREKC 327
Query: 365 HCRFHWCCYVLCDECKVTEWVNVCK 389
C FHWCCYV C EC V+ CK
Sbjct: 328 RCVFHWCCYVSCQECTRVYDVHTCK 352
>gi|13540477 wingless-type MMTV integration site family, member 3
[Homo sapiens]
Length = 355
Score = 266 bits (680), Expect = 2e-71
Identities = 138/359 (38%), Positives = 188/359 (52%), Gaps = 49/359 (13%)
Query: 38 GEPPLTANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSAL 97
G PL +C ++ GL +QL C ++ S +G+ + + ECQHQ R +RWNC+ +
Sbjct: 39 GSQPL----LCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTI 94
Query: 98 EGGGRLPHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRL 157
+ L +L + RESAF ++ +AGV AV +C+ G CGC
Sbjct: 95 DDS--LAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCD---------- 142
Query: 158 RAKLLQLQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSR 217
H PG G W+WGGC+ D DFG SR+F D+R
Sbjct: 143 ----------------SHHKGPPGEG----------WKWGGCSEDADFGVLVSREFADAR 176
Query: 218 EAPRDIQARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRE 277
E D ++ M HNN GR + +++ KCKCHG SGSC+ KTCW A P+FRA+G L++
Sbjct: 177 ENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKD 236
Query: 278 RLGRA--IFIDTHNRNSGAFQPRLRPRRL-----SGELVYFEKSPDFCERDPTMGSPGTR 330
+ A + ++ H + G + L +LVY+E SP+FCE +P GS GTR
Sbjct: 237 KYDSASEMVVEKHRESRGWVETLRAKYSLFKPPTERDLVYYENSPNFCEPNPETGSFGTR 296
Query: 331 GRACNKTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
R CN TS +DGC LCCGRGHN + R E+CHC FHWCCYV C EC V+ CK
Sbjct: 297 DRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYVSCQECIRIYDVHTCK 355
>gi|4885655 wingless-type MMTV integration site family, member 1
precursor [Homo sapiens]
Length = 370
Score = 264 bits (674), Expect = 1e-70
Identities = 143/350 (40%), Positives = 186/350 (53%), Gaps = 51/350 (14%)
Query: 50 TLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPH-HSA 108
+L LS++Q L +NP + S GL AV EC+ Q R++RWNC G PH
Sbjct: 60 SLQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPG----PHLFGK 115
Query: 109 ILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALS 168
I+ RG RE+AF F++ +AGV H+VA +CS G + SC C ++ G
Sbjct: 116 IVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRG---------------- 159
Query: 169 RGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPRDIQARMR 228
PG D W WGGC+ ++DFG F R+F+DS E RD++ M
Sbjct: 160 -------------------PGGPD-WHWGGCSDNIDFGRLFGREFVDSGEKGRDLRFLMN 199
Query: 229 IHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTH 288
+HNN GR V ++++CKCHG SGSC +TCW P RAVG LR+R A +
Sbjct: 200 LHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRVLYG 259
Query: 289 NRNSG----AFQPRLRPRRLS------GELVYFEKSPDFCERDPTMGSPGTRGRACNKTS 338
NR S A RL P + +LVYFEKSP+FC +G+ GT GRACN +S
Sbjct: 260 NRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSPNFCTYSGRLGTAGTAGRACNSSS 319
Query: 339 RLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVC 388
LDGC LCCGRGH Q ERC+C FHWCC+V C C T ++ C
Sbjct: 320 PALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSCRNCTHTRVLHEC 369
>gi|13518021 wingless-type MMTV integration site family, member 2B
isoform WNT-2B2 [Homo sapiens]
Length = 391
Score = 262 bits (670), Expect = 3e-70
Identities = 146/395 (36%), Positives = 203/395 (51%), Gaps = 45/395 (11%)
Query: 5 PRPRPPPSGLAGLLFLALCSRALSNEILGLKLPGEPP--------LTANTVCLTLSGLSK 56
P P P P+ G A A +L L LP L A +C + GL
Sbjct: 21 PVPVPSPAAPDGSRASARLGLACLLLLLLLTLPARVDTSWWYIGALGARVICDNIPGLVS 80
Query: 57 RQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRGFRE 116
RQ LC R PD+ S +G + ECQHQ R RWNC+ L+ + ++ R RE
Sbjct: 81 RQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHTV--FGRVMLRSSRE 138
Query: 117 SAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFPHS 176
+AF +++ +AGV+HA+ ACS G+L C C +RG+
Sbjct: 139 AAFVYAISSAGVVHAITRACSQGELSVCSC------------------DPYTRGRHHDQ- 179
Query: 177 LPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAP-RDIQARMRIHNNRVG 235
+ ++WGGC+ ++ +G +F++ F+D++E +D +A M +HNNR G
Sbjct: 180 --------------RGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCG 225
Query: 236 RQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHNRNSGAF 295
R V LK +CKCHG SGSC +TCWRA +FR G LR R A+ + +
Sbjct: 226 RTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQDGANFT 285
Query: 296 QPRLRPRRLSG-ELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRLLDGCGSLCCGRGHN 354
R RR + +LVYF+ SPD+C D GS GT GR C+KTS+ DGC +CCGRG++
Sbjct: 286 AARQGYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYD 345
Query: 355 VLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
R TRV +C C+FHWCC V C EC+ T V+ CK
Sbjct: 346 TTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCK 380
>gi|13518017 wingless-type MMTV integration site family, member 2B
isoform WNT-2B1 [Homo sapiens]
Length = 372
Score = 261 bits (667), Expect = 8e-70
Identities = 135/350 (38%), Positives = 190/350 (54%), Gaps = 37/350 (10%)
Query: 42 LTANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGG 101
L A +C + GL RQ LC R PD+ S +G + ECQHQ R RWNC+ L+
Sbjct: 47 LGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDH 106
Query: 102 RLPHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKL 161
+ ++ R RE+AF +++ +AGV+HA+ ACS G+L C C
Sbjct: 107 TV--FGRVMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSC--------------- 149
Query: 162 LQLQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAP- 220
+RG+ + ++WGGC+ ++ +G +F++ F+D++E
Sbjct: 150 ---DPYTRGRHHDQ---------------RGDFDWGGCSDNIHYGVRFAKAFVDAKEKRL 191
Query: 221 RDIQARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLG 280
+D +A M +HNNR GR V LK +CKCHG SGSC +TCWRA +FR G LR R
Sbjct: 192 KDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYD 251
Query: 281 RAIFIDTHNRNSGAFQPRLRPRRLSG-ELVYFEKSPDFCERDPTMGSPGTRGRACNKTSR 339
A+ + + R RR + +LVYF+ SPD+C D GS GT GR C+KTS+
Sbjct: 252 GAVQVMATQDGANFTAARQGYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSK 311
Query: 340 LLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
DGC +CCGRG++ R TRV +C C+FHWCC V C EC+ T V+ CK
Sbjct: 312 GTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCK 361
>gi|4507927 wingless-type MMTV integration site family member 2
precursor [Homo sapiens]
Length = 360
Score = 254 bits (648), Expect = 1e-67
Identities = 133/349 (38%), Positives = 188/349 (53%), Gaps = 37/349 (10%)
Query: 43 TANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGR 102
++ +C + GL Q LC R+PDV + QG+ ECQHQ R RWNC+ L+
Sbjct: 36 SSRVMCDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNTLDRDHS 95
Query: 103 LPHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLL 162
L +L R RESAF +++ +AGV+ A+ ACS G++ SC C K G
Sbjct: 96 L--FGRVLLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCDPKKMGS--------- 144
Query: 163 QLQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAP-R 221
+ + ++WGGC+ ++D+G KF+R F+D++E +
Sbjct: 145 ------------------------AKDSKGIFDWGGCSDNIDYGIKFARAFVDAKERKGK 180
Query: 222 DIQARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGR 281
D +A M +HNNR GR+ V LK++CKCHG SGSC +TCW A +FR G L +
Sbjct: 181 DARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNG 240
Query: 282 AIFIDTHNRNSGAFQPRLRPRR-LSGELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRL 340
AI + + +G R ++ +LVYFE SPD+C RD GS GT GR CN TSR
Sbjct: 241 AIQVVMNQDGTGFTVANERFKKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRG 300
Query: 341 LDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
+D C +CCGRG++ TR+ +C C+FHWCC V C +C V+ CK
Sbjct: 301 MDSCEVMCCGRGYDTSHVTRMTKCGCKFHWCCAVRCQDCLEALDVHTCK 349
>gi|40806205 wingless-type MMTV integration site family, member 5A
precursor [Homo sapiens]
Length = 380
Score = 243 bits (621), Expect = 2e-64
Identities = 130/356 (36%), Positives = 188/356 (52%), Gaps = 50/356 (14%)
Query: 44 ANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRL 103
A +C L+GLS+ Q LC D +G + ECQ+Q R +RWNCS ++
Sbjct: 65 AQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDNTSVF 124
Query: 104 PHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQ 163
+++ G RE+AF++++ AAGV++A++ AC G+L +CGC
Sbjct: 125 ---GRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGC----------------- 164
Query: 164 LQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPR-- 221
+R K P W WGGC ++D+G +F+++F+D+RE R
Sbjct: 165 -SRAARPKDLPRD-----------------WLWGGCGDNIDYGYRFAKEFVDARERERIH 206
Query: 222 ------DIQARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAAL 275
+ M +HNN GR+ V CKCHG SGSC KTCW +FR VG AL
Sbjct: 207 AKGSYESARILMNLHNNEAGRRTVYNLADVACKCHGVSGSCSLKTCWLQLADFRKVGDAL 266
Query: 276 RERLGRAIFIDTHNRNSGAFQPRLRPRRLSGELVYFEKSPDFCERDPTMGSPGTRGRACN 335
+E+ A + ++R + +LVY + SPD+C R+ + GS GT+GR CN
Sbjct: 267 KEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLVYIDPSPDYCVRNESTGSLGTQGRLCN 326
Query: 336 KTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVN--VCK 389
KTS +DGC +CCGRG++ + + ERCHC+FHWCCYV C +C TE V+ VCK
Sbjct: 327 KTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFHWCCYVKCKKC--TEIVDQFVCK 380
>gi|14249180 wingless-type MMTV integration site family, member 5B
precursor [Homo sapiens]
Length = 359
Score = 241 bits (614), Expect = 1e-63
Identities = 125/354 (35%), Positives = 180/354 (50%), Gaps = 46/354 (12%)
Query: 44 ANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRL 103
A VC L GLS Q LC + A +G + ECQHQ R +RWNCS +
Sbjct: 44 AQPVCSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQFRQRRWNCSTADNASVF 103
Query: 104 PHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQ 163
+++ G RE+AF+ ++ AAGV++A++ AC G+L +CGC
Sbjct: 104 ---GRVMQIGSRETAFTHAVSAAGVVNAISRACREGELSTCGC----------------- 143
Query: 164 LQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPRDI 223
+R K P W WGGC ++++G +F+++F+D+RE ++
Sbjct: 144 -SRTARPKDLPRD-----------------WLWGGCGDNVEYGYRFAKEFVDAREREKNF 185
Query: 224 --------QARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAAL 275
+ M + NN GR+ V + CKCHG SGSC KTCW EFR VG L
Sbjct: 186 AKGSEEQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRL 245
Query: 276 RERLGRAIFIDTHNRNSGAFQPRLRPRRLSGELVYFEKSPDFCERDPTMGSPGTRGRACN 335
+E+ A + + + +LVY + SPD+C R+ + GS GT+GR CN
Sbjct: 246 KEKYDSAAAMRVTRKGRLELVNSRFTQPTPEDLVYVDPSPDYCLRNESTGSLGTQGRLCN 305
Query: 336 KTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
KTS +DGC +CCGRG+N + +VERCHC+FHWCC+V C +C +CK
Sbjct: 306 KTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK 359
>gi|17402919 wingless-type MMTV integration site family, member 5B
precursor [Homo sapiens]
Length = 359
Score = 241 bits (614), Expect = 1e-63
Identities = 125/354 (35%), Positives = 180/354 (50%), Gaps = 46/354 (12%)
Query: 44 ANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRL 103
A VC L GLS Q LC + A +G + ECQHQ R +RWNCS +
Sbjct: 44 AQPVCSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQFRQRRWNCSTADNASVF 103
Query: 104 PHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQ 163
+++ G RE+AF+ ++ AAGV++A++ AC G+L +CGC
Sbjct: 104 ---GRVMQIGSRETAFTHAVSAAGVVNAISRACREGELSTCGC----------------- 143
Query: 164 LQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPRDI 223
+R K P W WGGC ++++G +F+++F+D+RE ++
Sbjct: 144 -SRTARPKDLPRD-----------------WLWGGCGDNVEYGYRFAKEFVDAREREKNF 185
Query: 224 --------QARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAAL 275
+ M + NN GR+ V + CKCHG SGSC KTCW EFR VG L
Sbjct: 186 AKGSEEQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRL 245
Query: 276 RERLGRAIFIDTHNRNSGAFQPRLRPRRLSGELVYFEKSPDFCERDPTMGSPGTRGRACN 335
+E+ A + + + +LVY + SPD+C R+ + GS GT+GR CN
Sbjct: 246 KEKYDSAAAMRVTRKGRLELVNSRFTQPTPEDLVYVDPSPDYCLRNESTGSLGTQGRLCN 305
Query: 336 KTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
KTS +DGC +CCGRG+N + +VERCHC+FHWCC+V C +C +CK
Sbjct: 306 KTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK 359
>gi|17017974 wingless-type MMTV integration site family, member 11
precursor [Homo sapiens]
Length = 354
Score = 235 bits (599), Expect = 6e-62
Identities = 132/365 (36%), Positives = 180/365 (49%), Gaps = 52/365 (14%)
Query: 35 KLPGEPPLTANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNC 94
K P L C L GL Q+ LC N ++ + + + C+ D RWNC
Sbjct: 32 KTPSALALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFADMRWNC 91
Query: 95 SALEGGGRLPHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQ 154
S++E P++ L+RG RESAF +++ AA + HA+A AC+ G L C CG
Sbjct: 92 SSIE---LAPNYLLDLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCG------- 141
Query: 155 DRLRAKLLQLQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDF----GEKFS 210
P PG P PG + WGGC ++ + G KFS
Sbjct: 142 -------------------------PVPGEPPGPGNR----WGGCADNLSYGLLMGAKFS 172
Query: 211 RDFLDSREAPRDIQARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRA 270
+ ++ MR+HN+ VGRQ + +L+ KCKCHG SGSC +TCW+ E +
Sbjct: 173 DAPMKVKKTGSQANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIRTCWKGLQELQD 232
Query: 271 VGAALRERLGRAIFIDTHNRNSGAFQPRLRPRRL------SGELVYFEKSPDFCERDPTM 324
V A L+ R A + +R G + L P+ L ELVY + SPDFC ++ +
Sbjct: 233 VAADLKTRYLSATKV--VHRPMGT-RKHLVPKDLDIRPVKDSELVYLQSSPDFCMKNEKV 289
Query: 325 GSPGTRGRACNKTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEW 384
GS GT+ R CNKTS D C +CCGRG+N VERCHC++HWCCYV C C+ T
Sbjct: 290 GSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVE 349
Query: 385 VNVCK 389
VCK
Sbjct: 350 RYVCK 354
>gi|17017976 wingless-type MMTV integration site family, member 9B
precursor [Homo sapiens]
Length = 357
Score = 231 bits (590), Expect = 6e-61
Identities = 141/406 (34%), Positives = 192/406 (47%), Gaps = 75/406 (18%)
Query: 8 RPPPS-GLAGLLFLALCSRALS------NEIL----GLKLPGEPPLT-ANTVCLTLSGLS 55
RPPP+ LAGL LAL + A S E+L GL P A+ L LS
Sbjct: 2 RPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQCDLLKLS 61
Query: 56 KRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRGFR 115
+RQ LC R P + + H+ + ECQ Q R +RWNCS LEG +LKRGF+
Sbjct: 62 RRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCS-LEG------RMGLLKRGFK 114
Query: 116 ESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFPH 175
E+AF +++ +A + H +A ACS G++ C C
Sbjct: 115 ETAFLYAVSSAALTHTLARACSAGRMERCTCD---------------------------- 146
Query: 176 SLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPRDIQARMRIHNNRVG 235
SP + W+WG C ++ + KF +FL S+ +D++AR HN VG
Sbjct: 147 --------DSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGSKRGNKDLRARADAHNTHVG 198
Query: 236 RQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHNRNS--- 292
+ V L+ CKCHG SGSC +TCW+ FR G L+ R A+ + + +
Sbjct: 199 IKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDSAVKVSSATNEALGR 258
Query: 293 ---------GAFQPRLRPRRLSGELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRLLDG 343
G+ L PR SG+LVY E SP FC P+ SPGT GR C++ +
Sbjct: 259 LELWAPARQGSLTKGLAPR--SGDLVYMEDSPSFCR--PSKYSPGTAGRVCSREA----S 310
Query: 344 CGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
C SLCCGRG++ + CHC+ WCCYV C +C E V CK
Sbjct: 311 CSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQEELVYTCK 356
>gi|17402916 wingless-type MMTV integration site family, member 16
isoform 1 precursor [Homo sapiens]
Length = 365
Score = 228 bits (580), Expect = 9e-60
Identities = 123/350 (35%), Positives = 170/350 (48%), Gaps = 50/350 (14%)
Query: 54 LSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGG-----GRLPHHSA 108
L+ RQ LC R P + S +G + + EC Q R +RWNC G P
Sbjct: 52 LNSRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGY 111
Query: 109 ILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALS 168
L G +E+AF ++++AAG++H+V +CS G + C C LQ
Sbjct: 112 ELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCD--------------TTLQN-- 155
Query: 169 RGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLD-----SREAPRDI 223
G S S G W WGGC+ D+ +G FSR FLD + +
Sbjct: 156 --------------GGSASEG----WHWGGCSDDVQYGMWFSRKFLDFPIGNTTGKENKV 197
Query: 224 QARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAI 283
M +HNN GRQ V + + C+CHG SGSC KTCW+ F +G L+++ +I
Sbjct: 198 LLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGHLLKDKYENSI 257
Query: 284 FIDTHNRNSGAFQPRLRPRRL----SGELVYFEKSPDFCERDPTMGSPGTRGRACNKTSR 339
I + + R + +R +L+Y KSP++C D +G PGT+GR CN+TS
Sbjct: 258 QISDKTKRK--MRRREKDQRKIPIHKDDLLYVNKSPNYCVEDKKLGIPGTQGRECNRTSE 315
Query: 340 LLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
DGC LCCGRG+N VERC C+F WCCYV C C+ V+ CK
Sbjct: 316 GADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK 365
>gi|17402914 wingless-type MMTV integration site family, member 16
isoform 2 [Homo sapiens]
Length = 355
Score = 228 bits (580), Expect = 9e-60
Identities = 123/350 (35%), Positives = 170/350 (48%), Gaps = 50/350 (14%)
Query: 54 LSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGG-----GRLPHHSA 108
L+ RQ LC R P + S +G + + EC Q R +RWNC G P
Sbjct: 42 LNSRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGY 101
Query: 109 ILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALS 168
L G +E+AF ++++AAG++H+V +CS G + C C LQ
Sbjct: 102 ELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCD--------------TTLQN-- 145
Query: 169 RGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLD-----SREAPRDI 223
G S S G W WGGC+ D+ +G FSR FLD + +
Sbjct: 146 --------------GGSASEG----WHWGGCSDDVQYGMWFSRKFLDFPIGNTTGKENKV 187
Query: 224 QARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAI 283
M +HNN GRQ V + + C+CHG SGSC KTCW+ F +G L+++ +I
Sbjct: 188 LLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGHLLKDKYENSI 247
Query: 284 FIDTHNRNSGAFQPRLRPRRL----SGELVYFEKSPDFCERDPTMGSPGTRGRACNKTSR 339
I + + R + +R +L+Y KSP++C D +G PGT+GR CN+TS
Sbjct: 248 QISDKTKRK--MRRREKDQRKIPIHKDDLLYVNKSPNYCVEDKKLGIPGTQGRECNRTSE 305
Query: 340 LLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
DGC LCCGRG+N VERC C+F WCCYV C C+ V+ CK
Sbjct: 306 GADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK 355
>gi|15082261 wingless-type MMTV integration site family, member 9A
[Homo sapiens]
Length = 365
Score = 216 bits (550), Expect = 3e-56
Identities = 126/372 (33%), Positives = 184/372 (49%), Gaps = 61/372 (16%)
Query: 31 ILGLKLPGEPPLTANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQ 90
IL L L E A+ L ++Q +C R+P V + ++ + ++ ECQ Q R +
Sbjct: 41 ILPLTLEPEAAAQAHYKACDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFE 100
Query: 91 RWNCSALEGGGRLPHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKG 150
RWNC+ LEG R +++LKRGF+E+AF +++ +AG+ HA+A ACS G++ C C
Sbjct: 101 RWNCT-LEGRYR----ASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCD--- 152
Query: 151 SGEQDRLRAKLLQLQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFS 210
+P ++ W+WGGC ++ + KF
Sbjct: 153 ---------------------------------EAPDLENREAWQWGGCGDNLKYSSKFV 179
Query: 211 RDFLDSREAPRDIQARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRA 270
++FL R + +D++AR+ HNN VG +V+ ++ CKCHG SGSC +TCWR F
Sbjct: 180 KEFL-GRRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHE 238
Query: 271 VGAALRERLGRAIFI-DTHNRNSGAFQPRLRPR-RLSG-----------ELVYFEKSPDF 317
VG L+ + A+ + T N +G PR R SG ELV+ + SP F
Sbjct: 239 VGKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTPELVHLDDSPSF 298
Query: 318 CERDPTMGSPGTRGRACNKTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCD 377
C SPGT GR C++ C S+CCGRGHN + C C+ WCCYV C
Sbjct: 299 CLAG--RFSPGTAGRRCHREK----NCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECR 352
Query: 378 ECKVTEWVNVCK 389
+C E V CK
Sbjct: 353 QCTQREEVYTCK 364
>gi|110735437 wingless-type MMTV integration site family, member 8B
precursor [Homo sapiens]
Length = 351
Score = 197 bits (502), Expect = 1e-50
Identities = 116/324 (35%), Positives = 161/324 (49%), Gaps = 50/324 (15%)
Query: 69 TASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRGFRESAFSFSMLAAGV 128
++S G + EC++Q RWNC E +L H L+ RE+AF ++ +AGV
Sbjct: 40 SSSVAAGAQSGIEECKYQFAWDRWNCP--ERALQLSSHGG-LRSANRETAFVHAISSAGV 96
Query: 129 MHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFPHSLPSPGPGSSPSP 188
M+ + CSLG +CGC +G+ G G
Sbjct: 97 MYTLTRNCSLGDFDNCGCDDSRNGQLG-------------------------GQG----- 126
Query: 189 GPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPRDIQARMRIHNNRVGRQVVTENLKRKCK 248
W WGGC+ ++ FGE S+ F+D+ E +D +A M +HNN GR+ V +KR CK
Sbjct: 127 -----WLWGGCSDNVGFGEAISKQFVDALETGQDARAAMNLHNNEAGRKAVKGTMKRTCK 181
Query: 249 CHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHN--RNSGAFQPRLRP--RRL 304
CHG SGSC +TCW PEFR VGA L+E+ A+ +D NS A + + R +
Sbjct: 182 CHGVSGSCTTQTCWLQLPEFREVGAHLKEKYHAALKVDLLQGAGNSAAGRGAIADTFRSI 241
Query: 305 S-GELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRLLD-----GCGSLC--CGRGHNVL 356
S ELV+ E SPD+C + T+G GT GR C + R L C LC CG
Sbjct: 242 STRELVHLEDSPDYCLENKTLGLLGTEGRECLRRGRALGRWERRSCRRLCGDCGLAVEER 301
Query: 357 RQTRVERCHCRFHWCCYVLCDECK 380
R V C+C+FHWCC V C++C+
Sbjct: 302 RAETVSSCNCKFHWCCAVRCEQCR 325
>gi|17505195 wingless-type MMTV integration site family, member 8A
[Homo sapiens]
Length = 351
Score = 189 bits (480), Expect = 4e-48
Identities = 110/332 (33%), Positives = 161/332 (48%), Gaps = 63/332 (18%)
Query: 69 TASALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRGFRESAFSFSMLAAGV 128
T S G + EC+ Q +RWNC E +L H+ L+ RE++F ++ +AGV
Sbjct: 40 TTSVALGAQSGIEECKFQFAWERWNCP--ENALQLSTHNR-LRSATRETSFIHAISSAGV 96
Query: 129 MHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFPHSLPSPGPGSSPSP 188
M+ + CS+G +CGC +G+ + G G
Sbjct: 97 MYIITKNCSMGDFENCGCDGSNNGK-------------------------TGGHG----- 126
Query: 189 GPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPRDIQARMRIHNNRVGRQVVTENLKRKCK 248
W WGGC+ +++FGE+ S+ F+DS E +D +A M +HNNR GR V +KR CK
Sbjct: 127 -----WIWGGCSDNVEFGERISKLFVDSLEKGKDARALMNLHNNRAGRLAVRATMKRTCK 181
Query: 249 CHGTSGSCQFKTCWRAAPEFRAVGAALRERLGRAIFIDTHNRN-------------SGAF 295
CHG SGSC +TCW EFR +G L+ + +A+ I+ R + AF
Sbjct: 182 CHGISGSCSIQTCWLQLAEFREMGDYLKAKYDQALKIEMDKRQLRAGNSAEGHWVPAEAF 241
Query: 296 QPRLRPRRLSGELVYFEKSPDFCERDPTMGSPGTRGRAC----NKTSRL-LDGCGSLC-- 348
P EL++ E+SPD+C + ++G GT GR C + TSR CG LC
Sbjct: 242 LP-----SAEAELIFLEESPDYCTCNSSLGIYGTEGRECLQNSHNTSRWERRSCGRLCTE 296
Query: 349 CGRGHNVLRQTRVERCHCRFHWCCYVLCDECK 380
CG + + C+C+F WCC V CD+C+
Sbjct: 297 CGLQVEERKTEVISSCNCKFQWCCTVKCDQCR 328
>gi|239752226 PREDICTED: hypothetical protein XP_002348164 [Homo
sapiens]
Length = 661
Score = 124 bits (311), Expect = 1e-28
Identities = 69/204 (33%), Positives = 102/204 (50%), Gaps = 37/204 (18%)
Query: 42 LTANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGGG 101
L AN +C + GL+ RQ +C PD +G + ++ECQ+Q R RWNCSAL G
Sbjct: 31 LGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGINECQYQFRFGRWNCSAL---G 87
Query: 102 RLPHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKL 161
L+ G RE+AF++++ AAGV HAV ACS G L +CGC + G ++
Sbjct: 88 EKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQGYYNQ----- 142
Query: 162 LQLQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAPR 221
+ W+WGGC+ D+ +G FSR F+D+RE +
Sbjct: 143 -----------------------------AEGWKWGGCSADVRYGIDFSRRFVDAREIKK 173
Query: 222 DIQARMRIHNNRVGRQVVTENLKR 245
+ + M +HNN GR+ +L+R
Sbjct: 174 NARRLMNLHNNEAGRKQKQLSLRR 197
>gi|239756853 PREDICTED: similar to hCG2042405 [Homo sapiens]
Length = 144
Score = 38.5 bits (88), Expect = 0.010
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 54 LSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGG 100
LS++Q LC R P + + +H+ + ECQ Q R +RWN S LE G
Sbjct: 50 LSRQQKQLCGREPSLAETLWDAMHLGL-ECQFQFRHERWNYS-LEAG 94
>gi|239751341 PREDICTED: hypothetical protein XP_002347812 [Homo
sapiens]
Length = 137
Score = 38.5 bits (88), Expect = 0.010
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 54 LSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGG 100
LS++Q LC R P + + +H+ + ECQ Q R +RWN S LE G
Sbjct: 43 LSRQQKQLCGREPSLAETLWDAMHLGL-ECQFQFRHERWNYS-LEAG 87
>gi|239745840 PREDICTED: hypothetical protein XP_002343602 [Homo
sapiens]
Length = 137
Score = 38.5 bits (88), Expect = 0.010
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 54 LSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGG 100
LS++Q LC R P + + +H+ + ECQ Q R +RWN S LE G
Sbjct: 43 LSRQQKQLCGREPSLAETLWDAMHLGL-ECQFQFRHERWNYS-LEAG 87
>gi|32479521 dishevelled 1 [Homo sapiens]
Length = 670
Score = 34.7 bits (78), Expect = 0.15
Identities = 27/115 (23%), Positives = 42/115 (36%), Gaps = 1/115 (0%)
Query: 107 SAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQA 166
S++LK GF + + + CS ++ G G+ +QD L
Sbjct: 447 SSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAAP 506
Query: 167 LSRGKSFPHSLPSPGPGSSPS-PGPQDTWEWGGCNHDMDFGEKFSRDFLDSREAP 220
G+ +P+ P P P P+ P ++ G G K S SR AP
Sbjct: 507 WPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAP 561
>gi|239756270 PREDICTED: StAR-related lipid transfer (START) domain
containing 9 [Homo sapiens]
Length = 4614
Score = 33.1 bits (74), Expect = 0.44
Identities = 27/117 (23%), Positives = 48/117 (41%), Gaps = 5/117 (4%)
Query: 227 MRIHNNRVGRQVVTENLKRKCKCHGTSG-----SCQFKTCWRAAPEFRAVGAALRERLGR 281
++IHN+ + V ++ + + H G S + T W + AVG+ + +
Sbjct: 2281 LKIHNSPLVTGVEHQDQSTETRSHSPEGNVRGRSSEAHTAWCGSVRSMAVGSHSQSGVPE 2340
Query: 282 AIFIDTHNRNSGAFQPRLRPRRLSGELVYFEKSPDFCERDPTMGSPGTRGRACNKTS 338
+I + T +R S + P+ + L L+ F S DF R + NK S
Sbjct: 2341 SIPLGTEDRISASTSPQDHGKDLRITLLGFSTSEDFASEAEVAVQKEIRVSSLNKVS 2397
>gi|4502907 chymase 1, mast cell preproprotein [Homo sapiens]
Length = 247
Score = 32.3 bits (72), Expect = 0.75
Identities = 50/184 (27%), Positives = 70/184 (38%), Gaps = 29/184 (15%)
Query: 17 LLFLALCSRALSNEILGLK--LPGEPPLTANTVCLTLSGLSKRQLG-LCLRNPDVTASAL 73
LL LCSRA + EI+G P P A +T +G SK G L RN +TA+
Sbjct: 8 LLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC 67
Query: 74 QGLHIAVHECQHQLRDQRWNCSALEGGGRLPH--------HSAILKRGFRESA------- 118
G I V H + ++ LE + H H I+ +E A
Sbjct: 68 AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVG 127
Query: 119 -----FSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSF 173
F+ + G M VA G L GS ++ +L+ QA S + F
Sbjct: 128 TLPFPSQFNFVPPGRMCRVAGWGRTGVLK------PGSDTLQEVKLRLMDPQACSHFRDF 181
Query: 174 PHSL 177
H+L
Sbjct: 182 DHNL 185
>gi|93102379 low density lipoprotein-related protein 1B precursor
[Homo sapiens]
Length = 4599
Score = 32.3 bits (72), Expect = 0.75
Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
Query: 334 CNKTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVCK 389
CN S L D C C G +L + RCHC W Y + C+V N C+
Sbjct: 4207 CNDDSLLDDSCKLTCENGGRCILNEKGDLRCHC---WPSY-SGERCEVNHCSNYCQ 4258
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,534,515
Number of Sequences: 37866
Number of extensions: 960930
Number of successful extensions: 4498
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 4253
Number of HSP's gapped (non-prelim): 186
length of query: 389
length of database: 18,247,518
effective HSP length: 104
effective length of query: 285
effective length of database: 14,309,454
effective search space: 4078194390
effective search space used: 4078194390
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.