Guide to the Human Genome
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Search of human proteins with 169207076

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169207076 PREDICTED: hypothetical protein [Homo sapiens]
         (330 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169207782 PREDICTED: hypothetical protein [Homo sapiens]           690   0.0  
gi|169207076 PREDICTED: hypothetical protein [Homo sapiens]           690   0.0  
gi|169207410 PREDICTED: hypothetical protein [Homo sapiens]           251   5e-67
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      67   2e-11
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        62   7e-10
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      62   9e-10
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    60   3e-09
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    60   3e-09
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    59   5e-09
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    59   5e-09
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...    59   5e-09
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    59   8e-09
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     57   2e-08
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                57   3e-08
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               56   4e-08
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...    56   5e-08
gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...    55   7e-08
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...    54   3e-07
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         54   3e-07
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...    54   3e-07
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    53   4e-07
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho...    53   4e-07
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho...    53   4e-07
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    53   4e-07
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    53   4e-07
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    53   4e-07
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        53   4e-07
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        53   4e-07
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          52   1e-06
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 52   1e-06

>gi|169207782 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 330

 Score =  690 bits (1781), Expect = 0.0
 Identities = 330/330 (100%), Positives = 330/330 (100%)

Query: 1   MRGVGPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIP 60
           MRGVGPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIP
Sbjct: 1   MRGVGPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIP 60

Query: 61  TLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSL 120
           TLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSL
Sbjct: 61  TLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSL 120

Query: 121 QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGT 180
           QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGT
Sbjct: 121 QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGT 180

Query: 181 DPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRWVRR 240
           DPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRWVRR
Sbjct: 181 DPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRWVRR 240

Query: 241 RVPCPLPGLRPHERAGAALLATCRGNAPTPSACLTWLESKNKKNYDAGEACGGEKRRFHV 300
           RVPCPLPGLRPHERAGAALLATCRGNAPTPSACLTWLESKNKKNYDAGEACGGEKRRFHV
Sbjct: 241 RVPCPLPGLRPHERAGAALLATCRGNAPTPSACLTWLESKNKKNYDAGEACGGEKRRFHV 300

Query: 301 SPVLRPDRTPRAFRALSQRPPRVPELQQEM 330
           SPVLRPDRTPRAFRALSQRPPRVPELQQEM
Sbjct: 301 SPVLRPDRTPRAFRALSQRPPRVPELQQEM 330


>gi|169207076 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 330

 Score =  690 bits (1781), Expect = 0.0
 Identities = 330/330 (100%), Positives = 330/330 (100%)

Query: 1   MRGVGPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIP 60
           MRGVGPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIP
Sbjct: 1   MRGVGPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIP 60

Query: 61  TLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSL 120
           TLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSL
Sbjct: 61  TLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSL 120

Query: 121 QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGT 180
           QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGT
Sbjct: 121 QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGT 180

Query: 181 DPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRWVRR 240
           DPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRWVRR
Sbjct: 181 DPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRWVRR 240

Query: 241 RVPCPLPGLRPHERAGAALLATCRGNAPTPSACLTWLESKNKKNYDAGEACGGEKRRFHV 300
           RVPCPLPGLRPHERAGAALLATCRGNAPTPSACLTWLESKNKKNYDAGEACGGEKRRFHV
Sbjct: 241 RVPCPLPGLRPHERAGAALLATCRGNAPTPSACLTWLESKNKKNYDAGEACGGEKRRFHV 300

Query: 301 SPVLRPDRTPRAFRALSQRPPRVPELQQEM 330
           SPVLRPDRTPRAFRALSQRPPRVPELQQEM
Sbjct: 301 SPVLRPDRTPRAFRALSQRPPRVPELQQEM 330


>gi|169207410 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 225

 Score =  251 bits (642), Expect = 5e-67
 Identities = 131/160 (81%), Positives = 133/160 (83%), Gaps = 5/160 (3%)

Query: 1   MRGVGPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIP 60
           MRGVGPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIP
Sbjct: 1   MRGVGPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIP 60

Query: 61  TLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSL 120
           TLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSL
Sbjct: 61  TLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSL 120

Query: 121 Q-----DRLGRASRPGCPPSPRGSRQERGANSPGRSGARG 155
           Q      R GR  R   P    G R    A +   +  RG
Sbjct: 121 QGGRDRGRWGRWVRRRVPCPLPGLRPHERAGAALLATCRG 160



 Score =  231 bits (590), Expect = 5e-61
 Identities = 131/221 (59%), Positives = 142/221 (64%), Gaps = 27/221 (12%)

Query: 136 PRGSRQERGANSPGRSGARGCGGAAAL---QQEPTNFRGRPRPGARGTDPPGRTLP---- 188
           PRGS +   A +      RG     +L      P +    P P  RG  PP +T+P    
Sbjct: 6   PRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPP-QTIPTLFL 64

Query: 189 APLARPSTQPGRRP--GLGRAASPLGPRGAGVTGAGP-----------------ATQGGR 229
           A +   +  PG     G G ++ P   R  G  G  P                 + QGGR
Sbjct: 65  AGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQGGR 124

Query: 230 DRGRWGRWVRRRVPCPLPGLRPHERAGAALLATCRGNAPTPSACLTWLESKNKKNYDAGE 289
           DRGRWGRWVRRRVPCPLPGLRPHERAGAALLATCRGNAPTPSACLTWLESKNKKNY AGE
Sbjct: 125 DRGRWGRWVRRRVPCPLPGLRPHERAGAALLATCRGNAPTPSACLTWLESKNKKNYAAGE 184

Query: 290 ACGGEKRRFHVSPVLRPDRTPRAFRALSQRPPRVPELQQEM 330
           ACGGEKRRFHVSPVLRPDRTPRAFRALSQRPPRVPELQQEM
Sbjct: 185 ACGGEKRRFHVSPVLRPDRTPRAFRALSQRPPRVPELQQEM 225


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 68/200 (34%), Positives = 75/200 (37%), Gaps = 29/200 (14%)

Query: 46  PGPER-RG----PRPPQTIPTLFLAGVFSETEAPGSSTHVG-AGNSSDPATSRLGGSRGP 99
           PGPE  +G    P PP    T  L G+  E    GS    G  G    P    + G  GP
Sbjct: 701 PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGP 760

Query: 100 H----PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCP--PSPRGSRQERGANSPGRSGA 153
                P  PPGPAG               G    PG P    PRGS  ERG   P   G 
Sbjct: 761 RGPTGPIGPPGPAGQ----------PGDKGEGGAPGLPGIAGPRGSPGERGETGP--PGP 808

Query: 154 RGCGGAAALQQEPTNFRGRPRPGARGTD-PPGRTLPAPLARPSTQPGRRPGLGRAASPLG 212
            G  GA     EP     R  PG +G   PPG   P   + P+  PG +   G   SP G
Sbjct: 809 AGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGG 868

Query: 213 PRGAGVTGA----GPATQGG 228
           P  AG  GA    GP    G
Sbjct: 869 PGAAGFPGARGLPGPPGSNG 888



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 75/228 (32%), Positives = 91/228 (39%), Gaps = 48/228 (21%)

Query: 37  GSPLD--RNPLPG-------PERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSD 87
           GSP +   N LPG       P  RGP  P  IP     G   E  APG +   GA  + +
Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE--KGPAGERGAPGPAGPRGA--AGE 523

Query: 88  PATSRLGGSRGPH--PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGA 145
           P    + G  G    P  P GP GS   P   GS     G + RPG PP P G R + G 
Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGP-GSDGKPGPPGSQ----GESGRPG-PPGPSGPRGQPGV 577

Query: 146 ----------NSPGRSGARGCGGAAALQQEP-----TNFRGRPRPGARG-----TDPPG- 184
                      +PG++G RG  G    Q  P     T  +G P P   G     T PPG 
Sbjct: 578 MGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGP 637

Query: 185 ---RTLPAPLARP--STQPGRRPGLGRAASPLGPRGAGVTGAGPATQG 227
              + LP     P  + +PG     G A +P  P G G  GA P  +G
Sbjct: 638 QGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGA-PGERG 684



 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 75/223 (33%), Positives = 87/223 (39%), Gaps = 45/223 (20%)

Query: 37  GSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA----GNSSDPATSR 92
           GSP   N  PG  +RG   PQ       AG       PG +   G     G +  P    
Sbjct: 357 GSP-GSNGAPG--QRGEPGPQGH-----AGAQGPPGPPGINGSPGGKGEMGPAGIPGAPG 408

Query: 93  LGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGA------- 145
           L G+RGP     PGPAG+   P  RG   +  G+    G  P PRG R E G        
Sbjct: 409 LMGARGP-----PGPAGANGAPGLRGGAGEP-GKNGAKG-EPGPRGERGEAGIPGVPGAK 461

Query: 146 ------NSPGRSGARGCGGAAALQQEPTNFRGRPRP-GARGTDPP----GRTLPAPLARP 194
                  SPG  GA G  GAA  +  P  FRG   P G  G   P    G   PA     
Sbjct: 462 GEDGKDGSPGEPGANGLPGAAGERGAP-GFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520

Query: 195 STQPGR-----RPGL-GRAASPLGPRGAGVTGAGPATQGGRDR 231
           + +PGR      PG+ G   SP GP   G  G  P +QG   R
Sbjct: 521 AGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP-PGSQGESGR 562



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 66/202 (32%), Positives = 78/202 (38%), Gaps = 33/202 (16%)

Query: 37   GSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGS 96
            G P    P  G    GP  PQ        GV  E  +PG     G G +  P    L G 
Sbjct: 837  GPPGVAGPPGGSGPAGPPGPQ--------GVKGERGSPG-----GPGAAGFPGARGLPGP 883

Query: 97   RGPHPTL-PPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARG 155
             G +    PPGP+GS   P + G      G A   G P SP  S  +  A  PG  G+ G
Sbjct: 884  PGSNGNPGPPGPSGS---PGKDGPP----GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPG 936

Query: 156  CGGAAALQQEPTNFRGRPRPGARG-TDPPGRTLPAPLARPSTQ----PGRRPGLGRAASP 210
              G       P    G    GARG   PPG  +P P   P  Q       +PG    +  
Sbjct: 937  AQGPPG-APGPLGIAG--ITGARGLAGPPG--MPGPRGSPGPQGVKGESGKPGANGLSGE 991

Query: 211  LGPRG-AGVTG-AGPATQGGRD 230
             GP G  G+ G AG A + GRD
Sbjct: 992  RGPPGPQGLPGLAGTAGEPGRD 1013



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 66/209 (31%), Positives = 79/209 (37%), Gaps = 31/209 (14%)

Query: 46  PGPERRGPRPPQTIPTLF-LAGVFSETEAPGSSTHVGA----GNSSDPATSRLGGSRGPH 100
           PGP   GP  P+  P +    G      APG +   G     G    P  +   G +GP 
Sbjct: 563 PGPP--GPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPP 620

Query: 101 -PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGA 159
            PT P G  G    P  +G LQ   G    PG    P     +  A +PG  G +G  GA
Sbjct: 621 GPTGPGGDKGDTGPPGPQG-LQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGA 679

Query: 160 AALQQEPTNFRGRP-------RPGARG----TDPPGRTLPAPLARPSTQ--PGRRPGLGR 206
              ++ P    G P        PG  G      PPG   P     P  Q  PG R GLG 
Sbjct: 680 PG-ERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP--PGAAGTPGLQGMPGERGGLG- 735

Query: 207 AASPLGPRGAGVTGAGPATQG--GRDRGR 233
             SP GP+G      GP   G  G+D  R
Sbjct: 736 --SP-GPKGDKGEPGGPGADGVPGKDGPR 761



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 57/189 (30%), Positives = 66/189 (34%), Gaps = 45/189 (23%)

Query: 73   APGSSTHVGAGNSSDPA-TSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDR------- 123
            APG+  H G      PA  S   G  GP  P   PGPAGS   P  +G   D+       
Sbjct: 1042 APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERG 1101

Query: 124  -------LGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPG 176
                    G    PG P SP  + Q+    SPG +G RG  G +              PG
Sbjct: 1102 AAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSG------------PPG 1149

Query: 177  ARGTDPPGRTLPAPLARPSTQPGR-------RPGLGRAASPLGPRGA------GVTGAGP 223
              GT       P P+  P  +  R        PG      P GP GA      GV  A  
Sbjct: 1150 KDGTSGH----PGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAI 1205

Query: 224  ATQGGRDRG 232
            A  GG   G
Sbjct: 1206 AGIGGEKAG 1214



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 71/249 (28%), Positives = 83/249 (33%), Gaps = 53/249 (21%)

Query: 5   GPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIPTLFL 64
           GP G P    A   S   G+     R      G P +R  LPGP   G + P  IP    
Sbjct: 210 GPSGPPGPPGAIGPSGPAGKDGESGRP-----GRPGERG-LPGPP--GIKGPAGIPGF-- 259

Query: 65  AGVFSETEAPGSSTHVGA----GNSSDPATSRLGGSRG-PHPTLPPGPAGSLVFPERRG- 118
                    PG   H G     G   +     L G  G P     PGP G    P  RG 
Sbjct: 260 ---------PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGR 310

Query: 119 -------------SLQDRLGRASRPGCP-----PSPRGSRQERG-ANSPGRSGARGCGGA 159
                          +   G+   PG P     P   G++ E G A SPG +GA G  G 
Sbjct: 311 PGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE 370

Query: 160 AALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVT 219
               Q     +G P P      P G+    P   P       PGL  A  P GP GA   
Sbjct: 371 PG-PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGA-----PGLMGARGPPGPAGA--- 421

Query: 220 GAGPATQGG 228
              P  +GG
Sbjct: 422 NGAPGLRGG 430



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 61/183 (33%), Positives = 71/183 (38%), Gaps = 44/183 (24%)

Query: 83   GNSSDPATSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQ 141
            G S  P  + L G RGP  P   PG AG+   P R G+     G    PG   SP G + 
Sbjct: 978  GESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP----GSDGLPGRDGSP-GGKG 1032

Query: 142  ERGAN-SPG------------------RSGARGCGGAA--ALQQEPTNFRGRPRP-GARG 179
            +RG N SPG                  +SG RG  G A  A    P   RG P P G RG
Sbjct: 1033 DRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRG 1092

Query: 180  ----TDPPG-------RTLPA-PLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQG 227
                T   G       R  P  P A  S  P  + G   +  P GPRG      GP+   
Sbjct: 1093 DKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP----VGPSGPP 1148

Query: 228  GRD 230
            G+D
Sbjct: 1149 GKD 1151



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 65/240 (27%), Positives = 78/240 (32%), Gaps = 50/240 (20%)

Query: 44  PLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTL 103
           P   P  +GP+ P+  P     G+      PG     G+  S  P         GP    
Sbjct: 95  PTRPPNGQGPQGPKGDPGP--PGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYS 152

Query: 104 PPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGA-NSPGRSGARGCGGAAAL 162
           P   +  +      G L    G A  PG PP P G+    G+  SPG  G  G  G A  
Sbjct: 153 PQYDSYDVKSGVAVGGLAGYPGPAGPPG-PPGPPGTSGHPGSPGSPGYQGPPGEPGQAGP 211

Query: 163 QQEP--------------TNFRGRP-RPGARG-TDPPGRTLPAPLARPSTQPGRR----- 201
              P                  GRP RPG RG   PPG   PA +       G R     
Sbjct: 212 SGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGR 271

Query: 202 ------------------PGLGRAASPLGPRGA-------GVTGAGPATQGGRDRGRWGR 236
                             PG   A  P+GPRGA       G+ GA  A      RG  G+
Sbjct: 272 NGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQ 331



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 57/197 (28%), Positives = 67/197 (34%), Gaps = 60/197 (30%)

Query: 74  PGSSTHVG-AGNSSDPATSRLGGSRGPH----PTLPPGPAGSLVFPERRGSLQDRLGRAS 128
           PG +   G  G    P    + G RG       T PPGPAG   FP   G   +  G+  
Sbjct: 770 PGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAG---FPGAPGQNGEPGGKGE 826

Query: 129 R----------------------PGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEP 166
           R                      P  PP P+G + ERG  SPG  GA G  GA  L   P
Sbjct: 827 RGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERG--SPGGPGAAGFPGARGLPGPP 884

Query: 167 TNFRGRP----------------------RPGARGTDPPGRTLPAPLARPSTQPGRRPGL 204
            +  G P                       PG+ G   P      P  + S      PG 
Sbjct: 885 GS-NGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPG- 942

Query: 205 GRAASPLGPRGAGVTGA 221
             A  PLG   AG+TGA
Sbjct: 943 --APGPLGI--AGITGA 955


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 72/229 (31%), Positives = 87/229 (37%), Gaps = 48/229 (20%)

Query: 45  LPGP--ERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVG-AGNSSDPAT----SRLGGSR 97
           LPGP  E+  P PP       L G   +    G     G AGN  DP T     R G S 
Sbjct: 651 LPGPSGEKGEPGPPG----FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSG 706

Query: 98  GPHPTLPPGPAGS-----LVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSG 152
            P    P GP G         P  +G++ D  GR  +PG    P+G +   G   PG+ G
Sbjct: 707 EPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPG----PKGEQGPEGVGRPGKPG 762

Query: 153 ARGCGGAAALQQEPTNFRG---RPRPGARGTDPPGRTLPAP-------LARPSTQPGRR- 201
             G  G     Q P   +G    P P  RG   P     AP       L  P   PG   
Sbjct: 763 QPGLPGV----QGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTG 818

Query: 202 -------PGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRWVRRRVP 243
                  PG+  A  P+GP GA V+G       GRD G+ G+   R  P
Sbjct: 819 EKGAQGSPGVKGATGPVGPPGASVSG-----PPGRD-GQQGQTGLRGTP 861



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 70/228 (30%), Positives = 80/228 (35%), Gaps = 52/228 (22%)

Query: 46   PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGP------ 99
            PGP    P PP       L G+  +   PG           DP  +   G  GP      
Sbjct: 1200 PGP----PGPPGIQGPAGLDGLDGKDGKPGLR--------GDPGPAGPPGLMGPPGFKGK 1247

Query: 100  --HPTLP--------PGPAGSLVFPERRGSLQDRLGRASRPGCP-----PSPRGSRQERG 144
              HP LP        PGP GS   P   G     +G   RPG P     P P G     G
Sbjct: 1248 TGHPGLPGPKGDCGKPGPPGSTGRPGAEGE-PGAMGPQGRPGPPGHVGPPGPPGQPGPAG 1306

Query: 145  ANSPGRSGARGCGGAAAL-----QQEPTNFRGRP-RPGARGT----DPPGRT----LPAP 190
             ++ G  G RG  G   L     Q  P    G P  PG  G      PPG+      P P
Sbjct: 1307 ISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGP 1366

Query: 191  LARPST--QPGRRPGLGRAASPLGPRGAGVTG-AGPATQGGRDRGRWG 235
               P    Q G+    GRA  P GP  +G  G  GP    G +RG  G
Sbjct: 1367 KGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAG-ERGHPG 1413



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 56/204 (27%), Positives = 75/204 (36%), Gaps = 25/204 (12%)

Query: 65  AGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRL 124
           A V  ET A      V     S+   +  G   G      PGP GS      RG+   R+
Sbjct: 305 AKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRI 364

Query: 125 GRASRPGCPPSPRGSRQERGANSP----------GRSGARGCGGAAALQQEPTNFRGRPR 174
              +   C   P+G + E GA  P          G+ G +G GG   +  +P    GRP 
Sbjct: 365 SPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGR-DGRPG 423

Query: 175 P----GARG-TDPPGRTLPAPLARPSTQPG--RRPGLGRAAS------PLGPRGAGVTGA 221
                G +G    PG   P  LA     PG    PG+G   +      P GP+G   +  
Sbjct: 424 EICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSG 483

Query: 222 GPATQG-GRDRGRWGRWVRRRVPC 244
            P  +G G   G+ G    +  PC
Sbjct: 484 IPGKEGPGGKPGKPGVKGEKGDPC 507



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 41/145 (28%), Positives = 50/145 (34%), Gaps = 13/145 (8%)

Query: 83   GNSSDPATSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDR-----LGRASRPGCPPSP 136
            G   +     + GS GP  P  PPG  G++  P   G   +R      G    PG P  P
Sbjct: 1030 GQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQP 1089

Query: 137  RGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARG-TDPPGRTLPAPLARPS 195
                       PG  G RG  G+A  + EP        PG+ G   PPG   P     P 
Sbjct: 1090 GYPGATGPPGLPGIKGERGYTGSAGEKGEP------GPPGSEGLPGPPGPAGPRGERGPQ 1143

Query: 196  TQPGRRPGLGRAASPLGPRGAGVTG 220
               G +   G    P  P   G  G
Sbjct: 1144 GNSGEKGDQGFQGQPGFPGPPGPPG 1168



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 39/121 (32%), Positives = 49/121 (40%), Gaps = 18/121 (14%)

Query: 64   LAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTL----PPGPAGSLVFPERRGS 119
            LAG+  +   PG       G   +P T    G  GP        PPGP G      ++G 
Sbjct: 1324 LAGLPGQPGPPGHP-----GPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQ 1378

Query: 120  LQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPR-PGAR 178
              ++ GRA  PG  P   GS    G   PG +G RG  GA      P+   G P  PG+ 
Sbjct: 1379 AGEK-GRAGMPG-GPGKSGSMGPVGP--PGPAGERGHPGAPG----PSGSPGLPGVPGSM 1430

Query: 179  G 179
            G
Sbjct: 1431 G 1431



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 57/189 (30%), Positives = 66/189 (34%), Gaps = 57/189 (30%)

Query: 74   PGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCP 133
            PG S  +G      PA     G RG HP  P GP+GS   P   GS+ D +         
Sbjct: 1391 PGKSGSMGPVGPPGPA-----GERG-HPGAP-GPSGSPGLPGVPGSMGDMV------NYD 1437

Query: 134  PSPRGSRQE--------------------RGANSPGRSGARGCGGAAALQQEPTNFRGRP 173
               R  RQE                      A +PGR G  G  GA              
Sbjct: 1438 EIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPG------------ 1485

Query: 174  RPGARGTDPPGRTLPAPLARPSTQ--PGRRPGLGRAASPLGPRGAGVTGAG-----PATQ 226
            RPGA G+  PG  LP  + R   Q  PG R GL       G  G G+ G       P  Q
Sbjct: 1486 RPGAPGS--PG--LPGQIGREGRQGLPGVR-GLPGTKGEKGDIGIGIAGENGLPGPPGPQ 1540

Query: 227  GGRDRGRWG 235
            G    G+ G
Sbjct: 1541 GPPGYGKMG 1549



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 19/113 (16%)

Query: 125 GRASRPGCPPSPRGSRQERG-ANSPGRSGARGCGGAAALQQEPT------------NFRG 171
           GRA  PG     +G+  E G A SPG  G  G  G    + EP             + R 
Sbjct: 590 GRAGVPGLK-GEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRV 648

Query: 172 RPRPGARG----TDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTG 220
              PG  G      PPG  LP    + + + G +   G A +P  P   G TG
Sbjct: 649 VALPGPSGEKGEPGPPGFGLPGKQGK-AGERGLKGQKGDAGNPGDPGTPGTTG 700


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 68/195 (34%), Positives = 84/195 (43%), Gaps = 26/195 (13%)

Query: 47  GPER-RGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPP 105
           GP+  RG   PQ        GV  E   PG +    AG + +P      G++G +    P
Sbjct: 356 GPQGPRGSEGPQ--------GVRGEPGPPGPAG--AAGPAGNPGADGQPGAKGANGA--P 403

Query: 106 GPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGA-NSPGRSGARGCGGAAALQQ 164
           G AG+  FP  RG           PG PP P+G+  E GA  S G +GA+G  G   +Q 
Sbjct: 404 GIAGAPGFPGARGP-----SGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQG 458

Query: 165 EPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRR--PGLGRAASPLGPRG-AGVTG- 220
            P       + GARG +P    LP P       PG R  PG    A P GP G  G  G 
Sbjct: 459 PPGPAGEEGKRGARG-EPGPTGLPGPPGERG-GPGSRGFPGADGVAGPKGPAGERGSPGP 516

Query: 221 AGPATQGGRDRGRWG 235
           AGP    G + GR G
Sbjct: 517 AGPKGSPG-EAGRPG 530



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 83/263 (31%), Positives = 94/263 (35%), Gaps = 60/263 (22%)

Query: 45  LPGP--ERRGPRP---PQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRG 98
           LPGP  ER GP     P         G   E  +PG +   G+ G +  P  + L G++G
Sbjct: 480 LPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKG 539

Query: 99  -------PHP---TLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANS- 147
                  P P   T PPGPAG           QD      RPG PP P G+R + G    
Sbjct: 540 LTGSPGSPGPDGKTGPPGPAG-----------QD-----GRPG-PPGPPGARGQAGVMGF 582

Query: 148 PGRSGARGCGGAAALQQEPTNFRGRPRP----GARGTD-------PPGRTLPAPLARPST 196
           PG  GA G  G A         RG P P    G  G D       PPG   PA   R   
Sbjct: 583 PGPKGAAGEPGKA-------GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAG-ERGEQ 634

Query: 197 QPGRRPGLGRAASPLGPRG-------AGVTGAGPATQGGRDRGRWGRWVRRRVPCPLPGL 249
            P   PG      P GP G        GV G   A      RG  G    R V  P    
Sbjct: 635 GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPA 694

Query: 250 RPHERAGAALLATCRGNAPTPSA 272
            P    GA      +G+A  P A
Sbjct: 695 GPRGANGAPGNDGAKGDAGAPGA 717



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 65/209 (31%), Positives = 84/209 (40%), Gaps = 48/209 (22%)

Query: 81  GAGNSSDPATSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGS 139
           G+ + +D  T+ + G +G   P  P GPAG    P  R  +    G+   PG PP P   
Sbjct: 98  GSESPTDQETTGVEGPKGDTGPRGPRGPAG----PPGRDGIP---GQPGLPG-PPGP--- 146

Query: 140 RQERGANSPGRSGARGCGGAAALQ----QEPTNFRGRPRPGARGTDPPGRTLPAPLARPS 195
                   PG  G  G GG  A Q     +  +  G   PG  G   P R LP P   P 
Sbjct: 147 --------PGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGP-RGLPGPPGAPG 197

Query: 196 TQ----PGRRPGLGRAASPLGPRGAGVTGAGPATQGGRD--RGRWGRWVRRRVPCP---- 245
            Q    P   PG   A+ P+GPRG      GP  + G D   G+ GR   R  P P    
Sbjct: 198 PQGFQGPPGEPGEPGASGPMGPRGP----PGPPGKNGDDGEAGKPGRPGERGPPGPQGAR 253

Query: 246 -------LPGLRPHERAGAALLATCRGNA 267
                  LPG++ H   G + L   +G+A
Sbjct: 254 GLPGTAGLPGMKGHR--GFSGLDGAKGDA 280



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 72/255 (28%), Positives = 82/255 (32%), Gaps = 73/255 (28%)

Query: 37   GSPLDRNPLPGPERRG--PRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLG 94
            G+  D  P PGP      P P   +      G       PG++   GA     P     G
Sbjct: 833  GAKGDAGP-PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPP----G 887

Query: 95   GSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPG--CPPSPRGSRQERG-------A 145
             S    P  PPGPAG       RG      G A RPG   PP P G   E+G       A
Sbjct: 888  PSGNAGPPGPPGPAGKEGGKGPRGET----GPAGRPGEVGPPGPPGPAGEKGSPGADGPA 943

Query: 146  NSPGRSGARGCGGAAAL-----QQEPTNFRGRPRP----------GARGT-DPPGRTLPA 189
             +PG  G +G  G   +     Q+    F G P P          GA G   PPG   P 
Sbjct: 944  GAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPP 1003

Query: 190  PLARP-----------------------------STQPGRRPGLGRAASPLGPRGAGVTG 220
             LA P                              T P   PG   A    GP       
Sbjct: 1004 GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGP------- 1056

Query: 221  AGPATQGGRDRGRWG 235
             GPA + G DRG  G
Sbjct: 1057 VGPAGKSG-DRGETG 1070



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 67/201 (33%), Positives = 74/201 (36%), Gaps = 63/201 (31%)

Query: 46  PG-PERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLP 104
           PG P  RGP  PQ        G+      PG   H G         S L G++G     P
Sbjct: 238 PGRPGERGPPGPQGA-----RGLPGTAGLPGMKGHRGF--------SGLDGAKGDAG--P 282

Query: 105 PGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGA-NSPGRSGARGCGGAAALQ 163
            GP G    P   G+          PG    PRG   ERG   +PG +GARG  GA    
Sbjct: 283 AGPKGEPGSPGENGA----------PG-QMGPRGLPGERGRPGAPGPAGARGNDGAT--- 328

Query: 164 QEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGA----GVT 219
                       GA G  PPG T P   A P   PG     G  A P GPRG+    GV 
Sbjct: 329 ------------GAAG--PPGPTGP---AGPPGFPGAVGAKGE-AGPQGPRGSEGPQGVR 370

Query: 220 G----------AGPATQGGRD 230
           G          AGPA   G D
Sbjct: 371 GEPGPPGPAGAAGPAGNPGAD 391



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 60/199 (30%), Positives = 71/199 (35%), Gaps = 32/199 (16%)

Query: 37   GSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGG 95
            G P  + P      RGP  P   P L  AG       PG S   GA G    P      G
Sbjct: 980  GEPGKQGPSGASGERGPPGPMGPPGL--AG------PPGESGREGAPGAEGSPGRDGSPG 1031

Query: 96   SRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRASRPGC-----PPSPRGSRQERGANSP- 148
            ++G    T P GP G+   P   G +    G A + G      P  P G     GA  P 
Sbjct: 1032 AKGDRGETGPAGPPGAPGAPGAPGPV----GPAGKSGDRGETGPAGPAGPVGPVGARGPA 1087

Query: 149  GRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAA 208
            G  G RG  G    Q +      R   G +G  PPG         P   PG + G   A+
Sbjct: 1088 GPQGPRGDKGETGEQGDRGIKGHRGFSGLQG--PPG---------PPGSPGEQ-GPSGAS 1135

Query: 209  SPLGPRGAGVTGAGPATQG 227
             P GPRG   +   P   G
Sbjct: 1136 GPAGPRGPPGSAGAPGKDG 1154



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 61/202 (30%), Positives = 73/202 (36%), Gaps = 25/202 (12%)

Query: 37  GSPLDRNP--LPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVG-AGNSSDPATSRL 93
           G P +R    LPGP  +G R          AG      +PG     G  G    P  +  
Sbjct: 728 GMPGERGAAGLPGP--KGDRGD--------AGPKGADGSPGKDGVRGLTGPIGPPGPAGA 777

Query: 94  GGSRGPH-PTLPPGPAGSLVFPERRGSL--QDRLGRASRPGCPPSPRGSRQERGANSPGR 150
            G +G   P+ P GP G+   P  RG        G A  PG    P    +   A + G 
Sbjct: 778 PGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGD 837

Query: 151 SGARGCGGAAALQQEPTNFRGRPRPGARGT-DPPGRT-LPAPLARPSTQPGRRPGLGRAA 208
           +G  G  G A       N       GARG+  PPG T  P    R        PG    A
Sbjct: 838 AGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP-----PGPSGNA 892

Query: 209 SPLGPRG-AGVTGA-GPATQGG 228
            P GP G AG  G  GP  + G
Sbjct: 893 GPPGPPGPAGKEGGKGPRGETG 914



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 29/86 (33%), Positives = 33/86 (38%), Gaps = 19/86 (22%)

Query: 74   PGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCP 133
            PGS    G   +S PA     G RGP     PG AG+          +D L     P  P
Sbjct: 1123 PGSPGEQGPSGASGPA-----GPRGP-----PGSAGA--------PGKDGLNGLPGPIGP 1164

Query: 134  PSPRGSRQERG-ANSPGRSGARGCGG 158
            P PRG   + G    PG  G  G  G
Sbjct: 1165 PGPRGRTGDAGPVGPPGPPGPPGPPG 1190


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 77/239 (32%), Positives = 88/239 (36%), Gaps = 58/239 (24%)

Query: 46   PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLG--GSRG-PHPT 102
            PGP+     P    PT    GV     A G+    GA      A  R+G  GS G P P 
Sbjct: 863  PGPQGPSGAPGPQGPT----GVTGPKGARGAQGPPGA-TGFPGAAGRVGPPGSNGNPGPP 917

Query: 103  LPPGPAGSLVFPERRGSLQDRLGRASRPGC-----------------------PPSPRGS 139
             PPGP+G       RG      GRA  PG                        PP P+G 
Sbjct: 918  GPPGPSGKDGPKGARGD-SGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976

Query: 140  RQERG-ANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGT-DPPGRTLPAPLARPSTQ 197
              +RG    PG+ G RG  G      EP     +  PGA G   PPG   P  L  P+ +
Sbjct: 977  AGQRGIVGLPGQRGERGFPGLPGPSGEPGK---QGAPGASGDRGPPGPVGPPGLTGPAGE 1033

Query: 198  PGRR--------PGLGRAASPLGPRG-AGVTGA----------GPATQGGR--DRGRWG 235
            PGR         PG   AA   G RG  G  GA          GPA   G+  DRG  G
Sbjct: 1034 PGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1092



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 71/246 (28%), Positives = 91/246 (36%), Gaps = 46/246 (18%)

Query: 36   LGSPLDRNPLPGPERRGPR----PPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPA-- 89
            +G P    P   P R G      PP       + G   ET A G+    G   S  PA  
Sbjct: 1022 VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1081

Query: 90   TSRLG-----GSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERG 144
            T + G     G++GP    P GPAG+      +G   D+ G A  PG     RG +  RG
Sbjct: 1082 TGKQGDRGEAGAQGPMG--PSGPAGARGIQGPQGPRGDK-GEAGEPG----ERGLKGHRG 1134

Query: 145  ANS-------PGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPS-- 195
                      PG SG +G  G A     P+  RG P P           +P P+  P   
Sbjct: 1135 FTGLQGLPGPPGPSGDQGASGPAG----PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR 1190

Query: 196  -----TQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRWVRRRVPCPLPGLR 250
                 T P   PG      P GP G G+  +  A  G R++G          P PL  +R
Sbjct: 1191 GRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKG----------PDPLQYMR 1240

Query: 251  PHERAG 256
              + AG
Sbjct: 1241 ADQAAG 1246



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 51/159 (32%), Positives = 63/159 (39%), Gaps = 22/159 (13%)

Query: 83  GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQE 142
           GN  +P    + G  GP    PPGP G    P   G    + G+A   G PP P+G+R  
Sbjct: 225 GNPGEPGEPGVSGPMGPRG--PPGPPGK---PGDDGEA-GKPGKAGERG-PPGPQGARGF 277

Query: 143 RGANS----------PGRSGARGCGGAAALQQE--PTNFRGRPRP-GARG-TDPPGRTLP 188
            G             PG  GA+G  GA  ++ E       G P P G RG     GRT P
Sbjct: 278 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 337

Query: 189 APLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQG 227
           A  A      G +PG      P+GP G       P  +G
Sbjct: 338 AGAAGARGNDG-QPGPAGPPGPVGPAGGPGFPGAPGAKG 375



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 58/198 (29%), Positives = 73/198 (36%), Gaps = 39/198 (19%)

Query: 66  GVFSETEAPGSSTHVGA-------GNSSDPATSRLGGSRG----PHPTLPPGP---AGSL 111
           GV  E+ +PG +   G        G       +   G+RG    P P  PPGP   AG  
Sbjct: 306 GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 365

Query: 112 VFPERRGSL-----------QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAA 160
            FP   G+            +   G    PG P SP  +       + G  GA+G  GA 
Sbjct: 366 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 425

Query: 161 ALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRG----A 216
            +   P        PG RG  PPG         P  Q G  PG+       GP+G    A
Sbjct: 426 GIAGAP------GFPGPRG--PPGPQGATGPLGPKGQTG-EPGIAGFKGEQGPKGEPGPA 476

Query: 217 GVTGA-GPATQGGRDRGR 233
           G  GA GPA + G+   R
Sbjct: 477 GPQGAPGPAGEEGKRGAR 494



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 65/215 (30%), Positives = 72/215 (33%), Gaps = 43/215 (20%)

Query: 46  PGPERRGPRP-----PQTIPTLFLAGVFSETEAPGSSTHVGA-------GNSSDPATSRL 93
           PGP   G +P     P       L G   E   PG     GA       G    P T   
Sbjct: 671 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 730

Query: 94  GGSRGPH-PTLPPGPAGSLVFPERRGSLQ------DR--LGRASRPGCPPSPRGSRQERG 144
            G+ GP  P    GP G    P  RG+        DR  +G     G P    G      
Sbjct: 731 KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP 790

Query: 145 ANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARG-TDPPGRTLPAPLARP---STQPGR 200
              PG +GA G  G         +   R  PG RG T PPG   PA  A P     QPG 
Sbjct: 791 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPG---PAGFAGPPGADGQPGA 847

Query: 201 RPGLGRAAS--------PLGPRGA-------GVTG 220
           +   G A          P GP GA       GVTG
Sbjct: 848 KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG 882



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 82/295 (27%), Positives = 97/295 (32%), Gaps = 72/295 (24%)

Query: 3   GVGPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNP--LPGPERRGPRPPQTIP 60
           GVGP G P       + A   RG      L    G+P +R P  L GP+     P +   
Sbjct: 499 GVGPIGPPGE-----RGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGE 553

Query: 61  TLFLAGVFSETEAPGSSTHVG-AGNSSDPATSRLGGSRGPHPTLP-------PGPAGSLV 112
              L G    T  PG +   G  G S  P      G  GP            PGP G+  
Sbjct: 554 P-GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 612

Query: 113 FPERRGSL--------------QDRLGRASRPGCPPSPRGSRQERGA------------- 145
            P + G                    G A  PG P  P G R E+GA             
Sbjct: 613 EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG-PAGPAGERGEQGAPGPSGFQGLPGPP 671

Query: 146 ------NSPGRSGARGCGGAAALQQEPTNFRGRP----RPGARGTD-------PPGRTLP 188
                   PG  G  G  GA  L   P   RG P     PGA+G          PG   P
Sbjct: 672 GPPGEGGKPGDQGVPGEAGAPGL-VGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 730

Query: 189 APLARPSTQPGRR--------PGLGRAASPLGPRG--AGVTGAGPATQGGRDRGR 233
              + P+  PG +        PG   AA   GP+G    V   GP    G+D GR
Sbjct: 731 KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR 785



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 58/199 (29%), Positives = 71/199 (35%), Gaps = 48/199 (24%)

Query: 65   AGVFSETEAPGSSTHVGAGNSSDPA-TSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDR 123
            AG   +  APG     GA     P   +   G+RG       GP G+  FP   G +   
Sbjct: 854  AGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ-----GPPGATGFPGAAGRVGPP 908

Query: 124  LGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARG---- 179
             G    PG PP P G      +   G  GARG  G      EP        PG +G    
Sbjct: 909  -GSNGNPG-PPGPPGP-----SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 961

Query: 180  ------TDPPG-------------------RTLPAPLARPSTQPGRR--PGLGRAASPLG 212
                    PPG                   R  P  L  PS +PG++  PG      P G
Sbjct: 962  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG-LPGPSGEPGKQGAPGASGDRGPPG 1020

Query: 213  PRG-AGVTGAGPATQGGRD 230
            P G  G+T  GPA + GR+
Sbjct: 1021 PVGPPGLT--GPAGEPGRE 1037



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 40/131 (30%), Positives = 49/131 (37%), Gaps = 16/131 (12%)

Query: 105 PGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSP-GRSGARGCGGAAALQ 163
           PGP G    P   G ++D +G    P  PP P+G   E+G     G  G +G  G     
Sbjct: 100 PGPKGQKGEP---GDIKDIVG----PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 152

Query: 164 QEPTNFRGRPRPGARGTDPP---GRTLPAPLARPSTQPGRRPGLGRAASPLGPRG----A 216
            EP        PG  G   P   G    A +A    +      LG    P+GP G     
Sbjct: 153 GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 212

Query: 217 GVTGAGPATQG 227
           G  GA P  QG
Sbjct: 213 GPAGA-PGPQG 222


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 77/239 (32%), Positives = 88/239 (36%), Gaps = 58/239 (24%)

Query: 46   PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLG--GSRG-PHPT 102
            PGP+     P    PT    GV     A G+    GA      A  R+G  GS G P P 
Sbjct: 794  PGPQGPSGAPGPQGPT----GVTGPKGARGAQGPPGA-TGFPGAAGRVGPPGSNGNPGPP 848

Query: 103  LPPGPAGSLVFPERRGSLQDRLGRASRPGC-----------------------PPSPRGS 139
             PPGP+G       RG      GRA  PG                        PP P+G 
Sbjct: 849  GPPGPSGKDGPKGARGD-SGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907

Query: 140  RQERG-ANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGT-DPPGRTLPAPLARPSTQ 197
              +RG    PG+ G RG  G      EP     +  PGA G   PPG   P  L  P+ +
Sbjct: 908  AGQRGIVGLPGQRGERGFPGLPGPSGEPGK---QGAPGASGDRGPPGPVGPPGLTGPAGE 964

Query: 198  PGRR--------PGLGRAASPLGPRG-AGVTGA----------GPATQGGR--DRGRWG 235
            PGR         PG   AA   G RG  G  GA          GPA   G+  DRG  G
Sbjct: 965  PGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1023



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 71/246 (28%), Positives = 91/246 (36%), Gaps = 46/246 (18%)

Query: 36   LGSPLDRNPLPGPERRGPR----PPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPA-- 89
            +G P    P   P R G      PP       + G   ET A G+    G   S  PA  
Sbjct: 953  VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1012

Query: 90   TSRLG-----GSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERG 144
            T + G     G++GP    P GPAG+      +G   D+ G A  PG     RG +  RG
Sbjct: 1013 TGKQGDRGEAGAQGPMG--PSGPAGARGIQGPQGPRGDK-GEAGEPG----ERGLKGHRG 1065

Query: 145  ANS-------PGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPS-- 195
                      PG SG +G  G A     P+  RG P P           +P P+  P   
Sbjct: 1066 FTGLQGLPGPPGPSGDQGASGPAG----PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR 1121

Query: 196  -----TQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRWVRRRVPCPLPGLR 250
                 T P   PG      P GP G G+  +  A  G R++G          P PL  +R
Sbjct: 1122 GRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKG----------PDPLQYMR 1171

Query: 251  PHERAG 256
              + AG
Sbjct: 1172 ADQAAG 1177



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 51/159 (32%), Positives = 63/159 (39%), Gaps = 22/159 (13%)

Query: 83  GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQE 142
           GN  +P    + G  GP    PPGP G    P   G    + G+A   G PP P+G+R  
Sbjct: 156 GNPGEPGEPGVSGPMGPRG--PPGPPGK---PGDDGEA-GKPGKAGERG-PPGPQGARGF 208

Query: 143 RGANS----------PGRSGARGCGGAAALQQE--PTNFRGRPRP-GARG-TDPPGRTLP 188
            G             PG  GA+G  GA  ++ E       G P P G RG     GRT P
Sbjct: 209 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 268

Query: 189 APLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQG 227
           A  A      G +PG      P+GP G       P  +G
Sbjct: 269 AGAAGARGNDG-QPGPAGPPGPVGPAGGPGFPGAPGAKG 306



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 58/198 (29%), Positives = 73/198 (36%), Gaps = 39/198 (19%)

Query: 66  GVFSETEAPGSSTHVGA-------GNSSDPATSRLGGSRG----PHPTLPPGP---AGSL 111
           GV  E+ +PG +   G        G       +   G+RG    P P  PPGP   AG  
Sbjct: 237 GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 296

Query: 112 VFPERRGSL-----------QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAA 160
            FP   G+            +   G    PG P SP  +       + G  GA+G  GA 
Sbjct: 297 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 356

Query: 161 ALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRG----A 216
            +   P        PG RG  PPG         P  Q G  PG+       GP+G    A
Sbjct: 357 GIAGAP------GFPGPRG--PPGPQGATGPLGPKGQTG-EPGIAGFKGEQGPKGEPGPA 407

Query: 217 GVTGA-GPATQGGRDRGR 233
           G  GA GPA + G+   R
Sbjct: 408 GPQGAPGPAGEEGKRGAR 425



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 65/215 (30%), Positives = 72/215 (33%), Gaps = 43/215 (20%)

Query: 46  PGPERRGPRP-----PQTIPTLFLAGVFSETEAPGSSTHVGA-------GNSSDPATSRL 93
           PGP   G +P     P       L G   E   PG     GA       G    P T   
Sbjct: 602 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 661

Query: 94  GGSRGPH-PTLPPGPAGSLVFPERRGSLQ------DR--LGRASRPGCPPSPRGSRQERG 144
            G+ GP  P    GP G    P  RG+        DR  +G     G P    G      
Sbjct: 662 KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP 721

Query: 145 ANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARG-TDPPGRTLPAPLARP---STQPGR 200
              PG +GA G  G         +   R  PG RG T PPG   PA  A P     QPG 
Sbjct: 722 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPG---PAGFAGPPGADGQPGA 778

Query: 201 RPGLGRAAS--------PLGPRGA-------GVTG 220
           +   G A          P GP GA       GVTG
Sbjct: 779 KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG 813



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 82/295 (27%), Positives = 97/295 (32%), Gaps = 72/295 (24%)

Query: 3   GVGPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNP--LPGPERRGPRPPQTIP 60
           GVGP G P       + A   RG      L    G+P +R P  L GP+     P +   
Sbjct: 430 GVGPIGPPGE-----RGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGE 484

Query: 61  TLFLAGVFSETEAPGSSTHVG-AGNSSDPATSRLGGSRGPHPTLP-------PGPAGSLV 112
              L G    T  PG +   G  G S  P      G  GP            PGP G+  
Sbjct: 485 P-GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 543

Query: 113 FPERRGSL--------------QDRLGRASRPGCPPSPRGSRQERGA------------- 145
            P + G                    G A  PG P  P G R E+GA             
Sbjct: 544 EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG-PAGPAGERGEQGAPGPSGFQGLPGPP 602

Query: 146 ------NSPGRSGARGCGGAAALQQEPTNFRGRP----RPGARGTD-------PPGRTLP 188
                   PG  G  G  GA  L   P   RG P     PGA+G          PG   P
Sbjct: 603 GPPGEGGKPGDQGVPGEAGAPGL-VGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 661

Query: 189 APLARPSTQPGRR--------PGLGRAASPLGPRG--AGVTGAGPATQGGRDRGR 233
              + P+  PG +        PG   AA   GP+G    V   GP    G+D GR
Sbjct: 662 KGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR 716



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 58/199 (29%), Positives = 71/199 (35%), Gaps = 48/199 (24%)

Query: 65  AGVFSETEAPGSSTHVGAGNSSDPA-TSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDR 123
           AG   +  APG     GA     P   +   G+RG       GP G+  FP   G +   
Sbjct: 785 AGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ-----GPPGATGFPGAAGRVGPP 839

Query: 124 LGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARG---- 179
            G    PG PP P G      +   G  GARG  G      EP        PG +G    
Sbjct: 840 -GSNGNPG-PPGPPGP-----SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 892

Query: 180 ------TDPPG-------------------RTLPAPLARPSTQPGRR--PGLGRAASPLG 212
                   PPG                   R  P  L  PS +PG++  PG      P G
Sbjct: 893 DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG-LPGPSGEPGKQGAPGASGDRGPPG 951

Query: 213 PRG-AGVTGAGPATQGGRD 230
           P G  G+T  GPA + GR+
Sbjct: 952 PVGPPGLT--GPAGEPGRE 968



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 40/131 (30%), Positives = 49/131 (37%), Gaps = 16/131 (12%)

Query: 105 PGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSP-GRSGARGCGGAAALQ 163
           PGP G    P   G ++D +G    P  PP P+G   E+G     G  G +G  G     
Sbjct: 31  PGPKGQKGEP---GDIKDIVG----PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 83

Query: 164 QEPTNFRGRPRPGARGTDPP---GRTLPAPLARPSTQPGRRPGLGRAASPLGPRG----A 216
            EP        PG  G   P   G    A +A    +      LG    P+GP G     
Sbjct: 84  GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 143

Query: 217 GVTGAGPATQG 227
           G  GA P  QG
Sbjct: 144 GPAGA-PGPQG 153


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 80/271 (29%), Positives = 97/271 (35%), Gaps = 46/271 (16%)

Query: 5    GPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIPTLFL 64
            GPRG+P      A+ A+  RG      L    G+  D  P       G   P  +P   +
Sbjct: 1180 GPRGNPG-----AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 65   AGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRG-------PHPTLPPGPAGSLVFPERR 117
             G       PGS    GA     P  S + G +G       P P  PPG AG +  P   
Sbjct: 1235 PGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPP--- 1291

Query: 118  GSLQDRLGRASRPGCP--PSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRP 175
                   GR   PG P  P PRG    +G   PG  G +G  G       P     +  P
Sbjct: 1292 -------GRLGAPGTPGLPGPRGDPGFQG--FPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342

Query: 176  GARGTDPPGR----TLPAPLARPST--QPGRR-----PGLGRAASPLGPRGAGVTGAGPA 224
            G RG   PG     +LP     P T  +PG +     PG      P GPRG       P 
Sbjct: 1343 GVRG--DPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400

Query: 225  TQGGRDRGRWGRWVRRRVPCP-----LPGLR 250
            T G    G  G    +  P P     LPGL+
Sbjct: 1401 TPG--PAGEKGNKGSKGEPGPAGSDGLPGLK 1429



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 72/223 (32%), Positives = 85/223 (38%), Gaps = 35/223 (15%)

Query: 44  PLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTL 103
           P+PGP   GP  P   P     G       PGS      G   DP      G  G  P +
Sbjct: 653 PVPGPP--GPPGPPGHP-----GPQGPPGIPGS-----LGKCGDPGLPGPDGEPGI-PGI 699

Query: 104 ----PPGPAGSLVFPERRGSL--QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCG 157
               PPGP G   FP  +GSL    ++G    PG P  P G++ E     PG  G  G  
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLP-GAKGEPAVAMPGGPGTPGFP 758

Query: 158 GAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPST--QPGRRPGLGRAASPLGPRG 215
           G      E         PG  GT P    L  P   P     PG +   GR     GPRG
Sbjct: 759 GERGNSGEHGEIGLPGLPGLPGT-PGNEGLDGPRGDPGQPGPPGEQGPPGRCIE--GPRG 815

Query: 216 A-GVTGA-GPATQGGRDRGRWGRWVRRRVPCPLPGLRPHERAG 256
           A G+ G  G   Q GR RG+ G       P   PG+   +R+G
Sbjct: 816 AQGLPGLNGLKGQQGR-RGKTG-------PKGDPGIPGLDRSG 850



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 73/271 (26%), Positives = 92/271 (33%), Gaps = 58/271 (21%)

Query: 5    GPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERR----GPRPPQTIP 60
            GPRG P       +    GR +   R    + G     N L G + R    GP+    IP
Sbjct: 789  GPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL----NGLKGQQGRRGKTGPKGDPGIP 844

Query: 61   TLFLAGVFSETEAPGSSTHVGA----GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPER 116
             L  +G   ET +PG   H G     G    P    + G  G       G  G + FP  
Sbjct: 845  GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED-----GVIGMMGFP-- 897

Query: 117  RGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTN-------- 168
                    G    PG P +P    Q      PG  G RG  GA   Q +  N        
Sbjct: 898  --------GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949

Query: 169  ---FRGRP-------RPGARGT----DPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPR 214
                +G P        PG +G       PG      L  P+  PG R  LG   +P  P 
Sbjct: 950  VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009

Query: 215  GAGVTGA-----GPATQGGRDR----GRWGR 236
              G+ G+      P ++G R      GR GR
Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR 1040



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 47/154 (30%), Positives = 57/154 (37%), Gaps = 23/154 (14%)

Query: 78  THVGAGNSSDPATSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCP--P 134
           T+   G+   P      G+RGP  P+ PPG  GS       GS   R G    PG P   
Sbjct: 349 TYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS------PGS--SRPGLRGAPGWPGLK 400

Query: 135 SPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGA----RGTDPPGRTLPAP 190
             +G R   G ++ G  G+ GC G+  L   P    G P P      R   P    LP  
Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP----GPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 191 LARPSTQ----PGRRPGLGRAASPLGPRGAGVTG 220
           L  P       P   PGL     P  P   G+ G
Sbjct: 457 LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG 490



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 59/198 (29%), Positives = 70/198 (35%), Gaps = 23/198 (11%)

Query: 37  GSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGS 96
           GSP    P  GP   GP+         L G      APG     G       +T   G  
Sbjct: 605 GSPGPAGPA-GPPGYGPQGEPG-----LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 97  RGPHPTLPPGPAGSLVFPERRGSLQD--RLGRASRPGCP----PSPRGSRQERGANSPGR 150
             P P   PGP G    P   G   D    G    PG P    P P G + ++G   PG 
Sbjct: 659 GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG--FPGT 716

Query: 151 SGARGCGGAAALQQEPTNFRGRP-RPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAAS 209
            G+ GC G      EP    G+P  PGA+G   P   +P     P   PG R   G    
Sbjct: 717 KGSLGCPGKMG---EP-GLPGKPGLPGAKG--EPAVAMPGGPGTPGF-PGERGNSGEHGE 769

Query: 210 PLGPRGAGVTGAGPATQG 227
              P   G+ G  P  +G
Sbjct: 770 IGLPGLPGLPGT-PGNEG 786



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 58/195 (29%), Positives = 67/195 (34%), Gaps = 39/195 (20%)

Query: 47  GPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTL-P 104
           G E+  P  P       L G   +   PG     G  GN   P      G +G    + P
Sbjct: 284 GSEKGAPGDPG------LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 105 PGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSP---------GRSGARG 155
           PG  G    P          G    PG PP PRG+R  +G + P          R G RG
Sbjct: 338 PGFRG----PTEYYDTYQEKGDEGTPG-PPGPRGARGPQGPSGPPGVPGSPGSSRPGLRG 392

Query: 156 CGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPG--RRPGLGRAASPLGP 213
             G   L+      RGRP   A GT  PG             PG    PGL  +  P GP
Sbjct: 393 APGWPGLKGSKGE-RGRPGKDAMGT--PG------------SPGCAGSPGLPGSPGPPGP 437

Query: 214 RGAGVTGAGPATQGG 228
            G  V   GP    G
Sbjct: 438 PGDIVFRKGPPGDHG 452



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 45/186 (24%), Positives = 56/186 (30%), Gaps = 37/186 (19%)

Query: 65  AGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRG-------PHPTLPPGPAGSLVFPERR 117
           AG+  +  AP     +      DP      G +G       P P  PPGP G   FP   
Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209

Query: 118 GSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGA 177
           G              P  P+G   ER     G  G +G  G                PG 
Sbjct: 210 G--------------PRGPKGHMGERVIGHKGERGVKGLTGP---------------PGP 240

Query: 178 RGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRW 237
            GT     T P        + G +  +G    P GP G      G       D G  G+ 
Sbjct: 241 PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP-GPSGLPGESYGSEKGAPGDPGLQGKP 299

Query: 238 VRRRVP 243
            +  VP
Sbjct: 300 GKDGVP 305



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 43/162 (26%), Positives = 57/162 (35%), Gaps = 11/162 (6%)

Query: 64  LAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQD 122
           L G+      PG     G  G+   P  + L G  G      PG  G       +G    
Sbjct: 491 LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGF-----PGAQGDPGLKGEKGETLQ 545

Query: 123 RLGRASRPGCPPSPRGSRQERGAN----SPGRSGARGCGGAAALQQEPTNFRGRPRPGAR 178
             G+   PG  P  RG    +G +    +PG  G  G  G  AL  E  +      PG+ 
Sbjct: 546 PEGQVGVPG-DPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP 604

Query: 179 GTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTG 220
           G+  P      P   P  +PG +   G   +P  P  AG  G
Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRG 646



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 42/165 (25%), Positives = 54/165 (32%), Gaps = 35/165 (21%)

Query: 83  GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRG--------SLQDRLGRASRPGCPP 134
           G    P +    G  GP     PGP G   FP   G         +    G +  PG P 
Sbjct: 52  GFPGPPGSPGQKGFTGPEGL--PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109

Query: 135 SPRGSRQERGANSPGRSGAR---------------GCGGAAAL--------QQEPTNFRG 171
           +P  +        PG SG++               G  GAA L        ++E      
Sbjct: 110 TPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDA 169

Query: 172 RPRPGARGTDPPGRTLPAPLARPS-TQPGRRPGLGRAASPLGPRG 215
           +  PG  G   P + LP P   P    P   PG       +GPRG
Sbjct: 170 KGDPGLPGAPGP-QGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRG 213


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 80/271 (29%), Positives = 97/271 (35%), Gaps = 46/271 (16%)

Query: 5    GPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIPTLFL 64
            GPRG+P      A+ A+  RG      L    G+  D  P       G   P  +P   +
Sbjct: 1180 GPRGNPG-----AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 65   AGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRG-------PHPTLPPGPAGSLVFPERR 117
             G       PGS    GA     P  S + G +G       P P  PPG AG +  P   
Sbjct: 1235 PGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPP--- 1291

Query: 118  GSLQDRLGRASRPGCP--PSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRP 175
                   GR   PG P  P PRG    +G   PG  G +G  G       P     +  P
Sbjct: 1292 -------GRLGAPGTPGLPGPRGDPGFQG--FPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342

Query: 176  GARGTDPPGR----TLPAPLARPST--QPGRR-----PGLGRAASPLGPRGAGVTGAGPA 224
            G RG   PG     +LP     P T  +PG +     PG      P GPRG       P 
Sbjct: 1343 GVRG--DPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400

Query: 225  TQGGRDRGRWGRWVRRRVPCP-----LPGLR 250
            T G    G  G    +  P P     LPGL+
Sbjct: 1401 TPG--PAGEKGNKGSKGEPGPAGSDGLPGLK 1429



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 72/223 (32%), Positives = 85/223 (38%), Gaps = 35/223 (15%)

Query: 44  PLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTL 103
           P+PGP   GP  P   P     G       PGS      G   DP      G  G  P +
Sbjct: 653 PVPGPP--GPPGPPGHP-----GPQGPPGIPGS-----LGKCGDPGLPGPDGEPGI-PGI 699

Query: 104 ----PPGPAGSLVFPERRGSL--QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCG 157
               PPGP G   FP  +GSL    ++G    PG P  P G++ E     PG  G  G  
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLP-GAKGEPAVAMPGGPGTPGFP 758

Query: 158 GAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPST--QPGRRPGLGRAASPLGPRG 215
           G      E         PG  GT P    L  P   P     PG +   GR     GPRG
Sbjct: 759 GERGNSGEHGEIGLPGLPGLPGT-PGNEGLDGPRGDPGQPGPPGEQGPPGRCIE--GPRG 815

Query: 216 A-GVTGA-GPATQGGRDRGRWGRWVRRRVPCPLPGLRPHERAG 256
           A G+ G  G   Q GR RG+ G       P   PG+   +R+G
Sbjct: 816 AQGLPGLNGLKGQQGR-RGKTG-------PKGDPGIPGLDRSG 850



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 73/271 (26%), Positives = 92/271 (33%), Gaps = 58/271 (21%)

Query: 5    GPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERR----GPRPPQTIP 60
            GPRG P       +    GR +   R    + G     N L G + R    GP+    IP
Sbjct: 789  GPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL----NGLKGQQGRRGKTGPKGDPGIP 844

Query: 61   TLFLAGVFSETEAPGSSTHVGA----GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPER 116
             L  +G   ET +PG   H G     G    P    + G  G       G  G + FP  
Sbjct: 845  GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED-----GVIGMMGFP-- 897

Query: 117  RGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTN-------- 168
                    G    PG P +P    Q      PG  G RG  GA   Q +  N        
Sbjct: 898  --------GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949

Query: 169  ---FRGRP-------RPGARGT----DPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPR 214
                +G P        PG +G       PG      L  P+  PG R  LG   +P  P 
Sbjct: 950  VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009

Query: 215  GAGVTGA-----GPATQGGRDR----GRWGR 236
              G+ G+      P ++G R      GR GR
Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR 1040



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 47/154 (30%), Positives = 57/154 (37%), Gaps = 23/154 (14%)

Query: 78  THVGAGNSSDPATSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCP--P 134
           T+   G+   P      G+RGP  P+ PPG  GS       GS   R G    PG P   
Sbjct: 349 TYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS------PGS--SRPGLRGAPGWPGLK 400

Query: 135 SPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGA----RGTDPPGRTLPAP 190
             +G R   G ++ G  G+ GC G+  L   P    G P P      R   P    LP  
Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP----GPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 191 LARPSTQ----PGRRPGLGRAASPLGPRGAGVTG 220
           L  P       P   PGL     P  P   G+ G
Sbjct: 457 LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG 490



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 59/198 (29%), Positives = 70/198 (35%), Gaps = 23/198 (11%)

Query: 37  GSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGS 96
           GSP    P  GP   GP+         L G      APG     G       +T   G  
Sbjct: 605 GSPGPAGPA-GPPGYGPQGEPG-----LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 97  RGPHPTLPPGPAGSLVFPERRGSLQD--RLGRASRPGCP----PSPRGSRQERGANSPGR 150
             P P   PGP G    P   G   D    G    PG P    P P G + ++G   PG 
Sbjct: 659 GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG--FPGT 716

Query: 151 SGARGCGGAAALQQEPTNFRGRP-RPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAAS 209
            G+ GC G      EP    G+P  PGA+G   P   +P     P   PG R   G    
Sbjct: 717 KGSLGCPGKMG---EP-GLPGKPGLPGAKG--EPAVAMPGGPGTPGF-PGERGNSGEHGE 769

Query: 210 PLGPRGAGVTGAGPATQG 227
              P   G+ G  P  +G
Sbjct: 770 IGLPGLPGLPGT-PGNEG 786



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 58/195 (29%), Positives = 67/195 (34%), Gaps = 39/195 (20%)

Query: 47  GPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTL-P 104
           G E+  P  P       L G   +   PG     G  GN   P      G +G    + P
Sbjct: 284 GSEKGAPGDPG------LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 105 PGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSP---------GRSGARG 155
           PG  G    P          G    PG PP PRG+R  +G + P          R G RG
Sbjct: 338 PGFRG----PTEYYDTYQEKGDEGTPG-PPGPRGARGPQGPSGPPGVPGSPGSSRPGLRG 392

Query: 156 CGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPG--RRPGLGRAASPLGP 213
             G   L+      RGRP   A GT  PG             PG    PGL  +  P GP
Sbjct: 393 APGWPGLKGSKGE-RGRPGKDAMGT--PG------------SPGCAGSPGLPGSPGPPGP 437

Query: 214 RGAGVTGAGPATQGG 228
            G  V   GP    G
Sbjct: 438 PGDIVFRKGPPGDHG 452



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 45/186 (24%), Positives = 56/186 (30%), Gaps = 37/186 (19%)

Query: 65  AGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRG-------PHPTLPPGPAGSLVFPERR 117
           AG+  +  AP     +      DP      G +G       P P  PPGP G   FP   
Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209

Query: 118 GSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGA 177
           G              P  P+G   ER     G  G +G  G                PG 
Sbjct: 210 G--------------PRGPKGHMGERVIGHKGERGVKGLTGP---------------PGP 240

Query: 178 RGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRW 237
            GT     T P        + G +  +G    P GP G      G       D G  G+ 
Sbjct: 241 PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP-GPSGLPGESYGSEKGAPGDPGLQGKP 299

Query: 238 VRRRVP 243
            +  VP
Sbjct: 300 GKDGVP 305



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 43/162 (26%), Positives = 57/162 (35%), Gaps = 11/162 (6%)

Query: 64  LAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQD 122
           L G+      PG     G  G+   P  + L G  G      PG  G       +G    
Sbjct: 491 LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGF-----PGAQGDPGLKGEKGETLQ 545

Query: 123 RLGRASRPGCPPSPRGSRQERGAN----SPGRSGARGCGGAAALQQEPTNFRGRPRPGAR 178
             G+   PG  P  RG    +G +    +PG  G  G  G  AL  E  +      PG+ 
Sbjct: 546 PEGQVGVPG-DPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP 604

Query: 179 GTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTG 220
           G+  P      P   P  +PG +   G   +P  P  AG  G
Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRG 646



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 42/165 (25%), Positives = 54/165 (32%), Gaps = 35/165 (21%)

Query: 83  GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRG--------SLQDRLGRASRPGCPP 134
           G    P +    G  GP     PGP G   FP   G         +    G +  PG P 
Sbjct: 52  GFPGPPGSPGQKGFTGPEGL--PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109

Query: 135 SPRGSRQERGANSPGRSGAR---------------GCGGAAAL--------QQEPTNFRG 171
           +P  +        PG SG++               G  GAA L        ++E      
Sbjct: 110 TPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDA 169

Query: 172 RPRPGARGTDPPGRTLPAPLARPS-TQPGRRPGLGRAASPLGPRG 215
           +  PG  G   P + LP P   P    P   PG       +GPRG
Sbjct: 170 KGDPGLPGAPGP-QGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRG 213


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 80/271 (29%), Positives = 97/271 (35%), Gaps = 46/271 (16%)

Query: 5    GPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIPTLFL 64
            GPRG+P      A+ A+  RG      L    G+  D  P       G   P  +P   +
Sbjct: 1180 GPRGNPG-----AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 65   AGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRG-------PHPTLPPGPAGSLVFPERR 117
             G       PGS    GA     P  S + G +G       P P  PPG AG +  P   
Sbjct: 1235 PGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPP--- 1291

Query: 118  GSLQDRLGRASRPGCP--PSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRP 175
                   GR   PG P  P PRG    +G   PG  G +G  G       P     +  P
Sbjct: 1292 -------GRLGAPGTPGLPGPRGDPGFQG--FPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342

Query: 176  GARGTDPPGR----TLPAPLARPST--QPGRR-----PGLGRAASPLGPRGAGVTGAGPA 224
            G RG   PG     +LP     P T  +PG +     PG      P GPRG       P 
Sbjct: 1343 GVRG--DPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400

Query: 225  TQGGRDRGRWGRWVRRRVPCP-----LPGLR 250
            T G    G  G    +  P P     LPGL+
Sbjct: 1401 TPG--PAGEKGNKGSKGEPGPAGSDGLPGLK 1429



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 72/223 (32%), Positives = 85/223 (38%), Gaps = 35/223 (15%)

Query: 44  PLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTL 103
           P+PGP   GP  P   P     G       PGS      G   DP      G  G  P +
Sbjct: 653 PVPGPP--GPPGPPGHP-----GPQGPPGIPGS-----LGKCGDPGLPGPDGEPGI-PGI 699

Query: 104 ----PPGPAGSLVFPERRGSL--QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCG 157
               PPGP G   FP  +GSL    ++G    PG P  P G++ E     PG  G  G  
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLP-GAKGEPAVAMPGGPGTPGFP 758

Query: 158 GAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPST--QPGRRPGLGRAASPLGPRG 215
           G      E         PG  GT P    L  P   P     PG +   GR     GPRG
Sbjct: 759 GERGNSGEHGEIGLPGLPGLPGT-PGNEGLDGPRGDPGQPGPPGEQGPPGRCIE--GPRG 815

Query: 216 A-GVTGA-GPATQGGRDRGRWGRWVRRRVPCPLPGLRPHERAG 256
           A G+ G  G   Q GR RG+ G       P   PG+   +R+G
Sbjct: 816 AQGLPGLNGLKGQQGR-RGKTG-------PKGDPGIPGLDRSG 850



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 73/271 (26%), Positives = 92/271 (33%), Gaps = 58/271 (21%)

Query: 5    GPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERR----GPRPPQTIP 60
            GPRG P       +    GR +   R    + G     N L G + R    GP+    IP
Sbjct: 789  GPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL----NGLKGQQGRRGKTGPKGDPGIP 844

Query: 61   TLFLAGVFSETEAPGSSTHVGA----GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPER 116
             L  +G   ET +PG   H G     G    P    + G  G       G  G + FP  
Sbjct: 845  GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED-----GVIGMMGFP-- 897

Query: 117  RGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTN-------- 168
                    G    PG P +P    Q      PG  G RG  GA   Q +  N        
Sbjct: 898  --------GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949

Query: 169  ---FRGRP-------RPGARGT----DPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPR 214
                +G P        PG +G       PG      L  P+  PG R  LG   +P  P 
Sbjct: 950  VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009

Query: 215  GAGVTGA-----GPATQGGRDR----GRWGR 236
              G+ G+      P ++G R      GR GR
Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR 1040



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 47/154 (30%), Positives = 57/154 (37%), Gaps = 23/154 (14%)

Query: 78  THVGAGNSSDPATSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCP--P 134
           T+   G+   P      G+RGP  P+ PPG  GS       GS   R G    PG P   
Sbjct: 349 TYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS------PGS--SRPGLRGAPGWPGLK 400

Query: 135 SPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGA----RGTDPPGRTLPAP 190
             +G R   G ++ G  G+ GC G+  L   P    G P P      R   P    LP  
Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP----GPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 191 LARPSTQ----PGRRPGLGRAASPLGPRGAGVTG 220
           L  P       P   PGL     P  P   G+ G
Sbjct: 457 LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG 490



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 59/198 (29%), Positives = 70/198 (35%), Gaps = 23/198 (11%)

Query: 37  GSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGS 96
           GSP    P  GP   GP+         L G      APG     G       +T   G  
Sbjct: 605 GSPGPAGPA-GPPGYGPQGEPG-----LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 97  RGPHPTLPPGPAGSLVFPERRGSLQD--RLGRASRPGCP----PSPRGSRQERGANSPGR 150
             P P   PGP G    P   G   D    G    PG P    P P G + ++G   PG 
Sbjct: 659 GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG--FPGT 716

Query: 151 SGARGCGGAAALQQEPTNFRGRP-RPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAAS 209
            G+ GC G      EP    G+P  PGA+G   P   +P     P   PG R   G    
Sbjct: 717 KGSLGCPGKMG---EP-GLPGKPGLPGAKG--EPAVAMPGGPGTPGF-PGERGNSGEHGE 769

Query: 210 PLGPRGAGVTGAGPATQG 227
              P   G+ G  P  +G
Sbjct: 770 IGLPGLPGLPGT-PGNEG 786



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 58/195 (29%), Positives = 67/195 (34%), Gaps = 39/195 (20%)

Query: 47  GPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTL-P 104
           G E+  P  P       L G   +   PG     G  GN   P      G +G    + P
Sbjct: 284 GSEKGAPGDPG------LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 105 PGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSP---------GRSGARG 155
           PG  G    P          G    PG PP PRG+R  +G + P          R G RG
Sbjct: 338 PGFRG----PTEYYDTYQEKGDEGTPG-PPGPRGARGPQGPSGPPGVPGSPGSSRPGLRG 392

Query: 156 CGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPG--RRPGLGRAASPLGP 213
             G   L+      RGRP   A GT  PG             PG    PGL  +  P GP
Sbjct: 393 APGWPGLKGSKGE-RGRPGKDAMGT--PG------------SPGCAGSPGLPGSPGPPGP 437

Query: 214 RGAGVTGAGPATQGG 228
            G  V   GP    G
Sbjct: 438 PGDIVFRKGPPGDHG 452



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 45/186 (24%), Positives = 56/186 (30%), Gaps = 37/186 (19%)

Query: 65  AGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRG-------PHPTLPPGPAGSLVFPERR 117
           AG+  +  AP     +      DP      G +G       P P  PPGP G   FP   
Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209

Query: 118 GSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGA 177
           G              P  P+G   ER     G  G +G  G                PG 
Sbjct: 210 G--------------PRGPKGHMGERVIGHKGERGVKGLTGP---------------PGP 240

Query: 178 RGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRW 237
            GT     T P        + G +  +G    P GP G      G       D G  G+ 
Sbjct: 241 PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP-GPSGLPGESYGSEKGAPGDPGLQGKP 299

Query: 238 VRRRVP 243
            +  VP
Sbjct: 300 GKDGVP 305



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 43/162 (26%), Positives = 57/162 (35%), Gaps = 11/162 (6%)

Query: 64  LAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQD 122
           L G+      PG     G  G+   P  + L G  G      PG  G       +G    
Sbjct: 491 LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGF-----PGAQGDPGLKGEKGETLQ 545

Query: 123 RLGRASRPGCPPSPRGSRQERGAN----SPGRSGARGCGGAAALQQEPTNFRGRPRPGAR 178
             G+   PG  P  RG    +G +    +PG  G  G  G  AL  E  +      PG+ 
Sbjct: 546 PEGQVGVPG-DPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP 604

Query: 179 GTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTG 220
           G+  P      P   P  +PG +   G   +P  P  AG  G
Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRG 646



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 42/165 (25%), Positives = 54/165 (32%), Gaps = 35/165 (21%)

Query: 83  GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRG--------SLQDRLGRASRPGCPP 134
           G    P +    G  GP     PGP G   FP   G         +    G +  PG P 
Sbjct: 52  GFPGPPGSPGQKGFTGPEGL--PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109

Query: 135 SPRGSRQERGANSPGRSGAR---------------GCGGAAAL--------QQEPTNFRG 171
           +P  +        PG SG++               G  GAA L        ++E      
Sbjct: 110 TPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDA 169

Query: 172 RPRPGARGTDPPGRTLPAPLARPS-TQPGRRPGLGRAASPLGPRG 215
           +  PG  G   P + LP P   P    P   PG       +GPRG
Sbjct: 170 KGDPGLPGAPGP-QGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRG 213


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 72/239 (30%), Positives = 89/239 (37%), Gaps = 35/239 (14%)

Query: 5    GPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIPTLFL 64
            GPRG+P      A+ A+  RG      L    G+  D  P       G   P  +P   +
Sbjct: 1180 GPRGNPG-----AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 65   AGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRG-------PHPTLPPGPAGSLVFPERR 117
             G       PGS    GA     P  S + G +G       P P  PPG AG +  P   
Sbjct: 1235 PGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPP--- 1291

Query: 118  GSLQDRLGRASRPGCP--PSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRP 175
                   GR   PG P  P PRG    +G   PG  G +G  G       P     +  P
Sbjct: 1292 -------GRLGAPGTPGLPGPRGDPGFQG--FPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342

Query: 176  GARGTDPPGR----TLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRD 230
            G RG   PG     +LP     P T PG  PG+     P GP G  +   GP  + G+D
Sbjct: 1343 GVRG--DPGTLKIISLPGSPGPPGT-PG-EPGMQGEPGPPGPPG-NLGPCGPRGKPGKD 1396



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 72/223 (32%), Positives = 85/223 (38%), Gaps = 35/223 (15%)

Query: 44  PLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTL 103
           P+PGP   GP  P   P     G       PGS      G   DP      G  G  P +
Sbjct: 653 PVPGPP--GPPGPPGHP-----GPQGPPGIPGS-----LGKCGDPGLPGPDGEPGI-PGI 699

Query: 104 ----PPGPAGSLVFPERRGSL--QDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCG 157
               PPGP G   FP  +GSL    ++G    PG P  P G++ E     PG  G  G  
Sbjct: 700 GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLP-GAKGEPAVAMPGGPGTPGFP 758

Query: 158 GAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPST--QPGRRPGLGRAASPLGPRG 215
           G      E         PG  GT P    L  P   P     PG +   GR     GPRG
Sbjct: 759 GERGNSGEHGEIGLPGLPGLPGT-PGNEGLDGPRGDPGQPGPPGEQGPPGRCIE--GPRG 815

Query: 216 A-GVTGA-GPATQGGRDRGRWGRWVRRRVPCPLPGLRPHERAG 256
           A G+ G  G   Q GR RG+ G       P   PG+   +R+G
Sbjct: 816 AQGLPGLNGLKGQQGR-RGKTG-------PKGDPGIPGLDRSG 850



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 73/271 (26%), Positives = 92/271 (33%), Gaps = 58/271 (21%)

Query: 5    GPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERR----GPRPPQTIP 60
            GPRG P       +    GR +   R    + G     N L G + R    GP+    IP
Sbjct: 789  GPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL----NGLKGQQGRRGKTGPKGDPGIP 844

Query: 61   TLFLAGVFSETEAPGSSTHVGA----GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPER 116
             L  +G   ET +PG   H G     G    P    + G  G       G  G + FP  
Sbjct: 845  GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGED-----GVIGMMGFP-- 897

Query: 117  RGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTN-------- 168
                    G    PG P +P    Q      PG  G RG  GA   Q +  N        
Sbjct: 898  --------GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949

Query: 169  ---FRGRP-------RPGARGT----DPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPR 214
                +G P        PG +G       PG      L  P+  PG R  LG   +P  P 
Sbjct: 950  VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009

Query: 215  GAGVTGA-----GPATQGGRDR----GRWGR 236
              G+ G+      P ++G R      GR GR
Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR 1040



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 47/154 (30%), Positives = 57/154 (37%), Gaps = 23/154 (14%)

Query: 78  THVGAGNSSDPATSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCP--P 134
           T+   G+   P      G+RGP  P+ PPG  GS       GS   R G    PG P   
Sbjct: 349 TYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS------PGS--SRPGLRGAPGWPGLK 400

Query: 135 SPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGA----RGTDPPGRTLPAP 190
             +G R   G ++ G  G+ GC G+  L   P    G P P      R   P    LP  
Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP----GPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 191 LARPSTQ----PGRRPGLGRAASPLGPRGAGVTG 220
           L  P       P   PGL     P  P   G+ G
Sbjct: 457 LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG 490



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 59/198 (29%), Positives = 70/198 (35%), Gaps = 23/198 (11%)

Query: 37  GSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGS 96
           GSP    P  GP   GP+         L G      APG     G       +T   G  
Sbjct: 605 GSPGPAGPA-GPPGYGPQGEPG-----LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 97  RGPHPTLPPGPAGSLVFPERRGSLQD--RLGRASRPGCP----PSPRGSRQERGANSPGR 150
             P P   PGP G    P   G   D    G    PG P    P P G + ++G   PG 
Sbjct: 659 GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG--FPGT 716

Query: 151 SGARGCGGAAALQQEPTNFRGRP-RPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAAS 209
            G+ GC G      EP    G+P  PGA+G   P   +P     P   PG R   G    
Sbjct: 717 KGSLGCPGKMG---EP-GLPGKPGLPGAKG--EPAVAMPGGPGTPGF-PGERGNSGEHGE 769

Query: 210 PLGPRGAGVTGAGPATQG 227
              P   G+ G  P  +G
Sbjct: 770 IGLPGLPGLPGT-PGNEG 786



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 58/195 (29%), Positives = 67/195 (34%), Gaps = 39/195 (20%)

Query: 47  GPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTL-P 104
           G E+  P  P       L G   +   PG     G  GN   P      G +G    + P
Sbjct: 284 GSEKGAPGDPG------LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 105 PGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSP---------GRSGARG 155
           PG  G    P          G    PG PP PRG+R  +G + P          R G RG
Sbjct: 338 PGFRG----PTEYYDTYQEKGDEGTPG-PPGPRGARGPQGPSGPPGVPGSPGSSRPGLRG 392

Query: 156 CGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPG--RRPGLGRAASPLGP 213
             G   L+      RGRP   A GT  PG             PG    PGL  +  P GP
Sbjct: 393 APGWPGLKGSKGE-RGRPGKDAMGT--PG------------SPGCAGSPGLPGSPGPPGP 437

Query: 214 RGAGVTGAGPATQGG 228
            G  V   GP    G
Sbjct: 438 PGDIVFRKGPPGDHG 452



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 45/186 (24%), Positives = 56/186 (30%), Gaps = 37/186 (19%)

Query: 65  AGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRG-------PHPTLPPGPAGSLVFPERR 117
           AG+  +  AP     +      DP      G +G       P P  PPGP G   FP   
Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209

Query: 118 GSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGA 177
           G              P  P+G   ER     G  G +G  G                PG 
Sbjct: 210 G--------------PRGPKGHMGERVIGHKGERGVKGLTGP---------------PGP 240

Query: 178 RGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRW 237
            GT     T P        + G +  +G    P GP G      G       D G  G+ 
Sbjct: 241 PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP-GPSGLPGESYGSEKGAPGDPGLQGKP 299

Query: 238 VRRRVP 243
            +  VP
Sbjct: 300 GKDGVP 305



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 43/162 (26%), Positives = 57/162 (35%), Gaps = 11/162 (6%)

Query: 64  LAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQD 122
           L G+      PG     G  G+   P  + L G  G      PG  G       +G    
Sbjct: 491 LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGF-----PGAQGDPGLKGEKGETLQ 545

Query: 123 RLGRASRPGCPPSPRGSRQERGAN----SPGRSGARGCGGAAALQQEPTNFRGRPRPGAR 178
             G+   PG  P  RG    +G +    +PG  G  G  G  AL  E  +      PG+ 
Sbjct: 546 PEGQVGVPG-DPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSP 604

Query: 179 GTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTG 220
           G+  P      P   P  +PG +   G   +P  P  AG  G
Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRG 646



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 42/165 (25%), Positives = 54/165 (32%), Gaps = 35/165 (21%)

Query: 83  GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRG--------SLQDRLGRASRPGCPP 134
           G    P +    G  GP     PGP G   FP   G         +    G +  PG P 
Sbjct: 52  GFPGPPGSPGQKGFTGPEGL--PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109

Query: 135 SPRGSRQERGANSPGRSGAR---------------GCGGAAAL--------QQEPTNFRG 171
           +P  +        PG SG++               G  GAA L        ++E      
Sbjct: 110 TPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDA 169

Query: 172 RPRPGARGTDPPGRTLPAPLARPS-TQPGRRPGLGRAASPLGPRG 215
           +  PG  G   P + LP P   P    P   PG       +GPRG
Sbjct: 170 KGDPGLPGAPGP-QGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRG 213


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 75/225 (33%), Positives = 86/225 (38%), Gaps = 47/225 (20%)

Query: 45  LPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLP 104
           LPGP R  P P          G+  E    GS     +GN  +P      GS GP    P
Sbjct: 323 LPGP-RGIPGPVGAAGATGARGLVGEPGPAGSKGE--SGNKGEP------GSAGPQG--P 371

Query: 105 PGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERG-------ANSPGRSGARGCG 157
           PGP+G     E +       G A  PG PP  RGS   RG       A   G  G+RG  
Sbjct: 372 PGPSGE----EGKRGPNGEAGSAGPPG-PPGLRGSPGSRGLPGADGRAGVMGPPGSRGAS 426

Query: 158 GAAALQQEPTNFRGRP-RPGARGT----DPPGRTLPAPLARPSTQPG--RRPGLGRAASP 210
           G A ++  P    GRP  PG  G       PG   PA    P   PG   RPG      P
Sbjct: 427 GPAGVRG-PNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPG------P 479

Query: 211 LGPRGA-------GVTG-AGPATQGGR--DRGRWGRWVRRRVPCP 245
           +GP GA       G  G  GP    G+  D+G  G    R  P P
Sbjct: 480 IGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGP 524



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 75/227 (33%), Positives = 86/227 (37%), Gaps = 47/227 (20%)

Query: 73  APGSSTHVG-AGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDR-----LGR 126
           APG     G AG   +P  +   G+RGP    PPG AG    P + G   +R      G 
Sbjct: 107 APGPQGFQGPAGEPGEPGQTGPAGARGPAG--PPGKAGEDGHPGKPGRPGERGVVGPQGA 164

Query: 127 ASRPGCPPSP--RGSRQERGAN----------------SPGRSGARGCGGAAALQQEPTN 168
              PG P  P  +G R   G +                +PG +G  G  GA  L  E   
Sbjct: 165 RGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGR 224

Query: 169 FRGRPRP-GARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQG 227
             G P P GARG+D  G   P   A P    G  PG   A  P G  GA V  AGPA   
Sbjct: 225 V-GAPGPAGARGSD--GSVGPVGPAGPIGSAG-PPGFPGAPGPKGEIGA-VGNAGPAGPA 279

Query: 228 GRDRGRWGRWVRRRVPCPLPGLR----PHERAGAALLATCRGNAPTP 270
           G  RG  G          LPGL     P    GA  L   +G A  P
Sbjct: 280 G-PRGEVG----------LPGLSGPVGPPGNPGANGLTGAKGAAGLP 315



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 63/186 (33%), Positives = 73/186 (39%), Gaps = 40/186 (21%)

Query: 65  AGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRL 124
           AG   E   PG S   GA   + P      GSRGP    PPGP G+   P   G++    
Sbjct: 585 AGPRGERGPPGES---GAAGPTGPI-----GSRGPSG--PPGPDGNKGEPGVVGAV-GTA 633

Query: 125 GRASRPGCP--------PSPRGSRQERGAN----SPGRSGARGCGGAAALQQEPTNFRGR 172
           G +   G P        P  +G + E G      +PGR GARG  GA           G 
Sbjct: 634 GPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAV----------GA 683

Query: 173 PRP-GARG-TDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRG-AGVTGAGPATQGGR 229
           P P GA G     G   PA  A P   PG R  +G    P GP G AG  GA        
Sbjct: 684 PGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVG----PAGPNGFAGPAGAAGQPGAKG 739

Query: 230 DRGRWG 235
           +RG  G
Sbjct: 740 ERGAKG 745



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 53/159 (33%), Positives = 67/159 (42%), Gaps = 16/159 (10%)

Query: 73  APGSSTHVGAGNSSDPATSRLGGSRG----PHPTLPPGPAGSLVFPERRGSLQDRLGRAS 128
           APG    +GA  ++ PA     G RG    P  + P GP G+   P   G L    G A 
Sbjct: 260 APGPKGEIGAVGNAGPAGP--AGPRGEVGLPGLSGPVGPPGN---PGANG-LTGAKGAAG 313

Query: 129 RPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLP 188
            PG   +P G    RG   PG  GA G  GA  L  EP     +   G +G   PG   P
Sbjct: 314 LPGVAGAP-GLPGPRGI--PGPVGAAGATGARGLVGEPGPAGSKGESGNKGE--PGSAGP 368

Query: 189 APLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQG 227
                PS + G+R   G A S   P   G+ G+ P ++G
Sbjct: 369 QGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGS-PGSRG 406



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 65/211 (30%), Positives = 78/211 (36%), Gaps = 28/211 (13%)

Query: 74   PGSSTHVGAGNSSDP----ATSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRAS 128
            PG+   VGA  +  P      +   G+RG   P+ P GPAG+ V P      Q   G   
Sbjct: 951  PGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGA-VGPRGPSGPQGIRGDKG 1009

Query: 129  RPGCPPSPRGSRQERGANS----PGRSGARGCGGAAALQQEPTNFRGRPRP-GARGTDP- 182
             PG    PRG    +G N     PG +G  G  GA      P   RG   P G  G D  
Sbjct: 1010 EPG-EKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPG-SVGPAGPRGPAGPSGPAGKDGR 1067

Query: 183  ---PGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGA-GVTGAGPATQGGRDRGRWGRWV 238
               PG   PA +  P    G          P GP G  G  G    + GG D G  G + 
Sbjct: 1068 TGHPGTVGPAGIRGPQGHQG----------PAGPPGPPGPPGPPGVSGGGYDFGYDGDFY 1117

Query: 239  RRRVPCPLPGLRPHERAGAALLATCRGNAPT 269
            R   P   P LRP +    A L +      T
Sbjct: 1118 RADQPRSAPSLRPKDYEVDATLKSLNNQIET 1148



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 58/205 (28%), Positives = 75/205 (36%), Gaps = 23/205 (11%)

Query: 46  PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRG-PHPTL 103
           PGP+     P   +  +  AG    +  PG     G  G   +     L G  G P    
Sbjct: 615 PGPDGNKGEPG-VVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDG 673

Query: 104 PPGPAGSLVFPERRGSLQDR-LGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAAL 162
             G  G++  P   G+  DR    A+ P  P  PRGS  ERG   P  +G  G  G A  
Sbjct: 674 ARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGP--AGPNGFAGPAGA 731

Query: 163 QQEPTNFRGRPRPGARG-------TDPPGRTLPAPLARPSTQPGRR--------PGLGRA 207
             +P     R   G +G       T P G   PA    P    G R         G   A
Sbjct: 732 AGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGA 791

Query: 208 ASPLGPRG-AGVTG-AGPATQGGRD 230
           A   GP G +G++G  GP    G++
Sbjct: 792 AGRTGPPGPSGISGPPGPPGPAGKE 816



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 73/249 (29%), Positives = 83/249 (33%), Gaps = 64/249 (25%)

Query: 39  PLDRNPLPGPE----RRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRL 93
           P   N + GP       GP  P   P    AG   +   PG +   GA G +  P  S +
Sbjct: 746 PKGENGVVGPTGPVGAAGPAGPNGPPGP--AGSRGDGGPPGMTGFPGAAGRTGPPGPSGI 803

Query: 94  GGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGC--------------------P 133
            G  GP     PGPAG       RG  Q  +GR    G                     P
Sbjct: 804 SGPPGP-----PGPAGKEGLRGPRGD-QGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGP 857

Query: 134 PSPRGSRQERGANS----PGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRT--- 186
           P   G +   GA      PG  G RG  G A    EP        PGARG  PPG     
Sbjct: 858 PGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARG--PPGAVGSP 915

Query: 187 ----LPAPLARPSTQPGRRPGLGRAASP-----------LGPRG-AGVTG----AGPATQ 226
                P    R    PG     GR   P           +GP G AG  G     GPA +
Sbjct: 916 GVNGAPGEAGRDG-NPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGK 974

Query: 227 GGRDRGRWG 235
            G +RG  G
Sbjct: 975 HG-NRGETG 982



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 43/137 (31%), Positives = 50/137 (36%), Gaps = 29/137 (21%)

Query: 95  GSRGPH----------PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERG 144
           G RGP           PT PPGP G    P   G+   +       G  P P G    RG
Sbjct: 42  GERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD-GKGVGLGPGPMGLMGPRG 100

Query: 145 ANSPGRSGARGCGGAAALQQEPTNFRGRP-RPGARGTDPPGRTLPAPLARPSTQPGRRPG 203
              PG +GA G          P  F+G    PG      PG+T PA    P+  PG+   
Sbjct: 101 P--PGAAGAPG----------PQGFQGPAGEPGE-----PGQTGPAGARGPAGPPGKAGE 143

Query: 204 LGRAASPLGPRGAGVTG 220
            G    P  P   GV G
Sbjct: 144 DGHPGKPGRPGERGVVG 160


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 66/217 (30%), Positives = 76/217 (35%), Gaps = 64/217 (29%)

Query: 45  LPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLP 104
           LPGP  +G R P  +P     G+  +   PG       G   +     LGG        P
Sbjct: 320 LPGP--KGDRGPAGVP-----GLLGDRGEPGED-----GEPGEQGPQGLGG--------P 359

Query: 105 PGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQ 164
           PG  GS   P RRG              PP P+G     G   PG  G RG  G + L  
Sbjct: 360 PGLPGSAGLPGRRG--------------PPGPKGEAGPGGP--PGVPGIRGDQGPSGLAG 403

Query: 165 EPTNFRGRPRPGARGTDPPGRT----LPAPLARPS-----------------TQPGRR-- 201
           +P     R  PGA G  PPG T     P    RP                   QPG R  
Sbjct: 404 KPGVPGERGLPGAHG--PPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGP 461

Query: 202 ---PGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWG 235
              PGL   A P+GP+G       P   G    GR G
Sbjct: 462 SGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAG 498



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 66/217 (30%), Positives = 78/217 (35%), Gaps = 35/217 (16%)

Query: 39  PLDRNPLPGPERR-GPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSR 97
           P+D    PGP  + GPR P   P     G   +        H   G +  P  SR+G + 
Sbjct: 72  PMDLKGEPGPPGKPGPRGPPGPP-----GFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAG 126

Query: 98  GPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCG 157
            P      GP G    P  RG    R  +  R   PP P G     G   PG+ GA+G  
Sbjct: 127 PPGLPGKVGPPGQ---PGLRGEPGIRGDQGLRG--PPGPPGLPGPSGITIPGKPGAQGVP 181

Query: 158 GAAALQQEP----------------TNFRGRP-RPGARG----TDPPGRTLPAPLARPST 196
           G    Q EP                 N  G+P  PGA G      PPG   PA L +P  
Sbjct: 182 GPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGL 241

Query: 197 Q--PGRRPGLGRAASPLGPRGAGVTGA-GPATQGGRD 230
              PG     G +  P  P   G  GA GP    G D
Sbjct: 242 DGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVD 278



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 51/161 (31%), Positives = 55/161 (34%), Gaps = 25/161 (15%)

Query: 99  PHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGG 158
           P P   PGP G        G  Q  L  A   G  P P G     G   PG  G  G  G
Sbjct: 190 PGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPG 249

Query: 159 AAALQQEP--TNFRGRP-------RPGARGTDPPGRT-LPAPLARPSTQPGRRPGLGRAA 208
                  P     RG P        PG  G   PG   LP P   PS   G  PG     
Sbjct: 250 DKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQG-PSGAKG-EPGTRGPP 307

Query: 209 SPLGPRGAGVTGAGPATQGGRDRGRWGRWVRRRVPCPLPGL 249
             +GP G G+ G  P  +G  DRG          P  +PGL
Sbjct: 308 GLIGPTGYGMPGL-PGPKG--DRG----------PAGVPGL 335


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 61/191 (31%), Positives = 75/191 (39%), Gaps = 28/191 (14%)

Query: 53   PRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRG-PHPTLPPGPAGSL 111
            P PP T       G    T APG       G   +P  +   G +G   P  PPGP G  
Sbjct: 1275 PGPPGTPGPKGSRGSLGPTGAPGRM-----GAQGEPGLAGYDGHKGIVGPLGPPGPKGE- 1328

Query: 112  VFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANS-------PGRSGARGCGGAAALQQ 164
                 +G  Q   G+A  P  PP  RG   +RG          PG+ G +G  G    Q 
Sbjct: 1329 -----KGE-QGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQG 1382

Query: 165  EPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGA----GVTG 220
            +P +   R  PG +G+   G   P      +  PGRR   G    P GPRG     G+ G
Sbjct: 1383 QPGHPGPRGWPGPKGS--KGAEGPKGKQGKAGAPGRRGVQGLQGLP-GPRGVVGRQGLEG 1439

Query: 221  -AGPATQGGRD 230
             AGP    GRD
Sbjct: 1440 IAGPDGLPGRD 1450



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 63/226 (27%), Positives = 78/226 (34%), Gaps = 64/226 (28%)

Query: 41   DRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA----GNSSDPATSRLGGS 96
            D  PL  P  +G           L G   E    G S  +G     G+  DP      G 
Sbjct: 1169 DLGPLGTPGEQG-----------LIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGE 1217

Query: 97   RGPHPTL----PPGPAG--SLVFPERRGS---------------LQDRLGRASRPGCP-- 133
            +G    +    PPGP G   +  PE +                  Q +LG    PG P  
Sbjct: 1218 KGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGP 1277

Query: 134  ---PSPRGSRQERG-ANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPA 189
               P P+GSR   G   +PGR GA+G  G A         +G   P      PPG     
Sbjct: 1278 PGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYD----GHKGIVGP----LGPPG----- 1324

Query: 190  PLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWG 235
                P  + G +   G+A  P GP G      GP    G DRG  G
Sbjct: 1325 ----PKGEKGEQGEDGKAEGPPGPPG----DRGPVGDRG-DRGEPG 1361



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 44/125 (35%), Positives = 51/125 (40%), Gaps = 19/125 (15%)

Query: 94   GGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSP-GRSG 152
            GG   P    P GP GS   P  RG+   R  R   P  P   +GSR  +G   P GR G
Sbjct: 1036 GGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRG--PDGPAGEQGSRGLKGPPGPQGRPG 1093

Query: 153  ARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQ--PGRRPGLGRAASP 210
              G  G A           R   G+RG   PG  +P P   P T+  PG  PG      P
Sbjct: 1094 RPGQQGVAG---------ERGHLGSRGF--PG--IPGPSGPPGTKGLPG-EPGPQGPQGP 1139

Query: 211  LGPRG 215
            +GP G
Sbjct: 1140 IGPPG 1144



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 61/202 (30%), Positives = 69/202 (34%), Gaps = 44/202 (21%)

Query: 45  LPG-PERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTL 103
           LPG P  RGPR P         G +     PG       G   DP  S      G    +
Sbjct: 644 LPGIPGARGPRGPP--------GPYGNPGLPGPPG--AKGQKGDPGLSPGKAHDGAKGDM 693

Query: 104 P-PGPAGSLVFPERRGSLQDRLGRASRPG--CPPSPRGSRQERG----------ANSPGR 150
             PG +G+   P R+G  +   G A  PG    P P GS   +G             PG 
Sbjct: 694 GLPGLSGNPGPPGRKGH-KGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGP 752

Query: 151 SGARGCGGAAALQQEP--TNFRGRPR-PGARG-------------TDPPGRT-LPAPLAR 193
            G+RG  G   L   P     RG P  PG RG               PPG    P  L  
Sbjct: 753 KGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGL 812

Query: 194 PSTQPGRRPGLGRAASPLGPRG 215
           P   P   PGL      LGP G
Sbjct: 813 PG--PPGVPGLIGDLGVLGPIG 832



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 41/169 (24%), Positives = 60/169 (35%), Gaps = 19/169 (11%)

Query: 48  PERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGP 107
           P  RGPR      T       S T  P     VG    +    ++L  S    P LP   
Sbjct: 283 PAGRGPRGTVAPATPTKPQRTSPTN-PHQHMAVGGPAQTPLLPAKLSASNALDPMLPASV 341

Query: 108 AGSLVFPERRGSLQDRLGRASR-----PGCPPSPRGSRQERGANSPGRSGARGCGGAAAL 162
            GS   P    +   +   A++     P  P +P  S     +  P +  A         
Sbjct: 342 GGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTA--------- 392

Query: 163 QQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQP-GRRPGLGRAASP 210
              P++F     P  +   P  R +PA ++RP+ +P  R PG+ R   P
Sbjct: 393 ---PSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPP 438


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 63/192 (32%), Positives = 71/192 (36%), Gaps = 30/192 (15%)

Query: 70  ETEAPGSSTHVGA-GNSSDPATSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRA 127
           E   PG     G  G    P    + G RGP  P  PPGPAG               G+ 
Sbjct: 267 ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEP-------------GKP 313

Query: 128 SRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRT- 186
             PG P +P          SPG  G++G  G   +      F GR  PG  G  PPG   
Sbjct: 314 GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGS-RGFPGRGIPGPPG--PPGTAG 370

Query: 187 LPAPLAR--PSTQPGRRPGLGRAASPLGPRGA-GVTGAGPATQGGRDRGRWGRWVRRRVP 243
           LP  L R  P   PGRR   G    P GPRG  G     P        GR G        
Sbjct: 371 LPGELGRVGPVGDPGRRGPPGPPGPP-GPRGTIGFHDGDPLCPNACPPGRSGY------- 422

Query: 244 CPLPGLRPHERA 255
             LPG+R H+ A
Sbjct: 423 PGLPGMRGHKGA 434



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 44/146 (30%), Positives = 55/146 (37%), Gaps = 8/146 (5%)

Query: 82  AGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGC--PPSPRGS 139
           A +   P +   G    P P  PPGP G   FP + G ++   G    PG      P+G 
Sbjct: 778 AASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMG-IRGLPGIKGPPGALGLRGPKGD 836

Query: 140 RQERGANSPGRSGARGCGGAAALQQE--PTNFRGRPRPGARGTDPPGRTLPAPLARPSTQ 197
             E+G   P   G  G  GA  L  +  P ++    R G RG  PPG      +  P   
Sbjct: 837 LGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERG--PPGVAGIPGVPGPPGP 894

Query: 198 PGRRPGLGRAASPLGPRGAGVTGAGP 223
           PG  PG    AS     G      GP
Sbjct: 895 PG-LPGFCEPASCTMQAGQRAFNKGP 919



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 72/235 (30%), Positives = 82/235 (34%), Gaps = 46/235 (19%)

Query: 36  LGSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGG 95
           LGSP     LPG     P PP         GV  E   PG     GA      A     G
Sbjct: 645 LGSP----GLPGL----PGPPGLPGMKGDRGVVGE---PGPKGEQGASGEEGEA-----G 688

Query: 96  SRGPHPTLP-PGPAGSLVFPERRGSLQDRLGRASRPGC-----PPSPRGSRQERGANSPG 149
            RG    +  PGP GS   P   G L+   G    PG      PP PRG + E+GA   G
Sbjct: 689 ERGELGDIGLPGPKGSAGNPGEPG-LRGPEGSRGLPGVEGPRGPPGPRGVQGEQGAT--G 745

Query: 150 RSGARGCGGAAALQQEPTNFRGR-------------PRPGARGTDPPGRTLPAPLARPST 196
             G +G  G A   Q       R              RP +  T  PGR  P     P  
Sbjct: 746 LPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPG 805

Query: 197 QPGRRPGLGRAASP--LGPRGA-GVTGAGPATQGGRDRGRWGRWVRRRVPCPLPG 248
           + G    +G    P   GP GA G+ G         +RG  GR      P  LPG
Sbjct: 806 ENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRG-----PNGLPG 855



 Score = 35.0 bits (79), Expect = 0.092
 Identities = 63/248 (25%), Positives = 76/248 (30%), Gaps = 34/248 (13%)

Query: 36  LGSPLDRNPLPGPERRGPRPP-------QTIPTLFLAGVFSETEAPGSSTHVGA-GNSSD 87
           +G P  R P   P   GPR            P     G       PG   H GA G   +
Sbjct: 381 VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 440

Query: 88  PATSRLGGSRGPHPTL-------PPGPAG-----SLVFPERRGSLQDRLGRASRPGCPPS 135
           P      G  G    L       PPG  G      +V  +     +   G     G P +
Sbjct: 441 PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGA 500

Query: 136 PRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTD----------PPGR 185
           P    Q       G  G RG  GA  +   P        PG  G D           PG+
Sbjct: 501 PGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK 560

Query: 186 TLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDR-GRWG--RWVRRRV 242
             P   A     PG  PG+  A    G +G+      P   G   + G+ G    V  R 
Sbjct: 561 PGPPGDAGLQGLPG-VPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRG 619

Query: 243 PCPLPGLR 250
           P  LPG R
Sbjct: 620 PQGLPGSR 627


>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
           sapiens]
          Length = 678

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 58/173 (33%), Positives = 66/173 (38%), Gaps = 29/173 (16%)

Query: 88  PATSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGAN 146
           P    + G RGP  P  PPGPAG               G+   PG P +P          
Sbjct: 43  PGIDGIDGDRGPKGPPGPPGPAGEP-------------GKPGAPGKPGTPGADGLTGPDG 89

Query: 147 SPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRT-LPAPLAR--PSTQPGRRPG 203
           SPG  G++G  G   +      F GR  PG  G  PPG   LP  L R  P   PGRR  
Sbjct: 90  SPGSIGSKGQKGEPGVPGS-RGFPGRGIPGPPG--PPGTAGLPGELGRVGPVGDPGRRGP 146

Query: 204 LGRAASPLGPRGA-GVTGAGPATQGGRDRGRWGRWVRRRVPCPLPGLRPHERA 255
            G    P GPRG  G     P        GR G          LPG+R H+ A
Sbjct: 147 PGPPGPP-GPRGTIGFHDGDPLCPNACPPGRSGY-------PGLPGMRGHKGA 191



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 44/146 (30%), Positives = 55/146 (37%), Gaps = 8/146 (5%)

Query: 82  AGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGC--PPSPRGS 139
           A +   P +   G    P P  PPGP G   FP + G ++   G    PG      P+G 
Sbjct: 535 AASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMG-IRGLPGIKGPPGALGLRGPKGD 593

Query: 140 RQERGANSPGRSGARGCGGAAALQQE--PTNFRGRPRPGARGTDPPGRTLPAPLARPSTQ 197
             E+G   P   G  G  GA  L  +  P ++    R G RG  PPG      +  P   
Sbjct: 594 LGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERG--PPGVAGIPGVPGPPGP 651

Query: 198 PGRRPGLGRAASPLGPRGAGVTGAGP 223
           PG  PG    AS     G      GP
Sbjct: 652 PG-LPGFCEPASCTMQAGQRAFNKGP 676



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 72/235 (30%), Positives = 82/235 (34%), Gaps = 46/235 (19%)

Query: 36  LGSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGG 95
           LGSP     LPG     P PP         GV  E   PG     GA      A     G
Sbjct: 402 LGSP----GLPGL----PGPPGLPGMKGDRGVVGE---PGPKGEQGASGEEGEA-----G 445

Query: 96  SRGPHPTLP-PGPAGSLVFPERRGSLQDRLGRASRPGC-----PPSPRGSRQERGANSPG 149
            RG    +  PGP GS   P   G L+   G    PG      PP PRG + E+GA   G
Sbjct: 446 ERGELGDIGLPGPKGSAGNPGEPG-LRGPEGSRGLPGVEGPRGPPGPRGVQGEQGAT--G 502

Query: 150 RSGARGCGGAAALQQEPTNFRGR-------------PRPGARGTDPPGRTLPAPLARPST 196
             G +G  G A   Q       R              RP +  T  PGR  P     P  
Sbjct: 503 LPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPG 562

Query: 197 QPGRRPGLGRAASP--LGPRGA-GVTGAGPATQGGRDRGRWGRWVRRRVPCPLPG 248
           + G    +G    P   GP GA G+ G         +RG  GR      P  LPG
Sbjct: 563 ENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRG-----PNGLPG 612



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 56/199 (28%), Positives = 68/199 (34%), Gaps = 21/199 (10%)

Query: 44  PLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPT 102
           P P  E   P  P    T    G+     +PGS   +G+ G   +P      G  G    
Sbjct: 61  PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGS---IGSKGQKGEPGVPGSRGFPGRGIP 117

Query: 103 LPPGPAGSLVFP---ERRGSLQDRLGRASRPGCPPSPRGSRQERG----------ANSPG 149
            PPGP G+   P    R G + D  GR   PG PP P G R   G          A  PG
Sbjct: 118 GPPGPPGTAGLPGELGRVGPVGDP-GRRGPPG-PPGPPGPRGTIGFHDGDPLCPNACPPG 175

Query: 150 RSGARGCGGAAALQQEPTNFRGRPRPGARGTD-PPGRTLPAPLARPSTQPGRRPGLGRAA 208
           RSG  G  G    +          R G +G +   G         P    G R G+    
Sbjct: 176 RSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLR-GITGIV 234

Query: 209 SPLGPRGAGVTGAGPATQG 227
              G +GA      P  QG
Sbjct: 235 GDKGEKGARGLDGEPGPQG 253



 Score = 35.0 bits (79), Expect = 0.092
 Identities = 63/248 (25%), Positives = 76/248 (30%), Gaps = 34/248 (13%)

Query: 36  LGSPLDRNPLPGPERRGPRPP-------QTIPTLFLAGVFSETEAPGSSTHVGA-GNSSD 87
           +G P  R P   P   GPR            P     G       PG   H GA G   +
Sbjct: 138 VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 197

Query: 88  PATSRLGGSRGPHPTL-------PPGPAG-----SLVFPERRGSLQDRLGRASRPGCPPS 135
           P      G  G    L       PPG  G      +V  +     +   G     G P +
Sbjct: 198 PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGA 257

Query: 136 PRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTD----------PPGR 185
           P    Q       G  G RG  GA  +   P        PG  G D           PG+
Sbjct: 258 PGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK 317

Query: 186 TLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDR-GRWG--RWVRRRV 242
             P   A     PG  PG+  A    G +G+      P   G   + G+ G    V  R 
Sbjct: 318 PGPPGDAGLQGLPG-VPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRG 376

Query: 243 PCPLPGLR 250
           P  LPG R
Sbjct: 377 PQGLPGSR 384


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 63/199 (31%), Positives = 76/199 (38%), Gaps = 33/199 (16%)

Query: 46   PG-PERRGPRPPQTIPTLFLAGVFSETEAPGSST-HVGAGNSSDPATSRLGGSRG-PHPT 102
            PG P  RG +  +  P L   G      APG S   + AG   DP    L G RG P P 
Sbjct: 1219 PGKPGLRGQKGDRGFPGL--QGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPA 1276

Query: 103  LPPGPAGSLVFPERRGSLQDRLGRASRPGCP--PSPRGSRQERGANSPGRSGARGCGGAA 160
             PPGP G               G    PG P  P P+G + ++G   PG SG  G  G  
Sbjct: 1277 GPPGPPGP----------SSNQGDTGDPGFPGIPGPKGPKGDQGI--PGFSGLPGELGLK 1324

Query: 161  ALQQEPTNFRGRPRPGARGTDP-----PGRTLPAPLARPSTQPGRRPGLGRAASPLGPRG 215
             ++ EP  F G P       DP      G+  P   +     PG+ P       P GP G
Sbjct: 1325 GMRGEP-GFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLG 1383

Query: 216  -------AGVTGAGPATQG 227
                    G+TG  P  QG
Sbjct: 1384 LPGIDGIPGLTG-DPGAQG 1401



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 57/187 (30%), Positives = 72/187 (38%), Gaps = 37/187 (19%)

Query: 64   LAGVFSETEAPGSSTHVGA----------------------GNSSDPATSRLGGSRGPHP 101
            +AG+  E   PGSS H GA                      G +  P T    G+ GP  
Sbjct: 1134 VAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSI 1193

Query: 102  TLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAA 161
            T  PGPAG       +G     +G   +PG     RG + +RG   PG  G  G  GA  
Sbjct: 1194 TGVPGPAGLPGPKGEKGYPGIGIGAPGKPGL----RGQKGDRG--FPGLQGPAGLPGAPG 1247

Query: 162  LQQEPTNFRGRP----RPGARG-TDPPGRTLPAPLARPSTQPGRR--PGLGRAASPLGPR 214
            +   P+   G+P    RPG  G    PG   P     PS+  G    PG      P GP+
Sbjct: 1248 ISL-PSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPK 1306

Query: 215  G-AGVTG 220
            G  G+ G
Sbjct: 1307 GDQGIPG 1313



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 59/222 (26%), Positives = 76/222 (34%), Gaps = 46/222 (20%)

Query: 43  NPLPG-PERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA----------GNSSDP--A 89
           N +PG P + GPR P  +      G       PG   + G           G+  DP  A
Sbjct: 106 NGIPGHPGQPGPRGPPGLDGC--NGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLA 163

Query: 90  TSRLGGSRGPHPTLP-----PGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERG 144
                G +G  P LP      GP G+  FP   G      G    PG PP P G     G
Sbjct: 164 PGSFKGMKGD-PGLPGLDGITGPQGAPGFPGAVGPAGPP-GLQGPPG-PPGPLGPDGNMG 220

Query: 145 ANSPGRSGARGCGGAAALQQEPTN-----FRGRPR--------PGARG----TDPPGRTL 187
               G  G +G  G       P +     F G P+        PG +G    + PPG   
Sbjct: 221 LGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPG--- 277

Query: 188 PAPLARPSTQPGRR--PGLGRAASPLGPRGAGVTGAGPATQG 227
             P    + + G +   G+     P GP G+      P  QG
Sbjct: 278 -FPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQG 318



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 49/166 (29%), Positives = 64/166 (38%), Gaps = 30/166 (18%)

Query: 83   GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSP-----R 137
            G    P  S   G++G       G  G++ FP  +G    ++G +   G P +P      
Sbjct: 1082 GPKGQPGESGFKGTKGRD-----GLIGNIGFPGNKGE-DGKVGVSGDVGLPGAPGFPGVA 1135

Query: 138  GSRQERGANSPGRSGARGCGGAAALQQ--EPTNFRGRP-------RPGARGT-DPPGRTL 187
            G R E G   PG SG +G  G         P  F G P        PG +GT   PG ++
Sbjct: 1136 GMRGEPGL--PGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSI 1193

Query: 188  -----PAPLARPSTQPGRRPGLG-RAASPLGPRGAGVTGAGPATQG 227
                 PA L  P  + G  PG+G  A    G RG       P  QG
Sbjct: 1194 TGVPGPAGLPGPKGEKG-YPGIGIGAPGKPGLRGQKGDRGFPGLQG 1238



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 42/152 (27%), Positives = 56/152 (36%), Gaps = 20/152 (13%)

Query: 37   GSPLDRNPLPGPERRG-PRPPQTIPTLFLAGVFSETEAPGSSTHVGA----GNSSDPATS 91
            G+P ++     P   G P P + +  L+L G      + GS+   G     G +  P   
Sbjct: 939  GTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPP 998

Query: 92   RLGGSRGPHPTL--------PPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQER 143
             L G+ G    +        PPG  G    P  +GS     G    PG P    GS+  R
Sbjct: 999  GLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSS----GITGFPGMP-GESGSQGIR 1053

Query: 144  GANSPGRSGARGCGGAAALQQEPTNFRGRPRP 175
            G  SPG  GA G  G      +     G P P
Sbjct: 1054 G--SPGLPGASGLPGLKGDNGQTVEISGSPGP 1083



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 15/77 (19%)

Query: 104 PPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERG-ANSPGRSGARGCGGAAAL 162
           PPGP G +  P  +G+  DR              GS   +G A +PG  G  G  G    
Sbjct: 499 PPGPWGLIGLPGLKGARGDR--------------GSGGAQGPAGAPGLVGPLGPSGPKGK 544

Query: 163 QQEPTNFRGRPRPGARG 179
           + EP     +  PG RG
Sbjct: 545 KGEPILSTIQGMPGDRG 561



 Score = 28.5 bits (62), Expect = 8.6
 Identities = 45/169 (26%), Positives = 57/169 (33%), Gaps = 26/169 (15%)

Query: 74  PGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLV-FPERRGSLQDRLGRASRPGC 132
           PG     G G   +     L G +G HP  P  P   L   P  RG   D+ G+   PG 
Sbjct: 587 PGLPGDGGQGFPGEKGLPGLPGEKG-HPGPPGLPGNGLPGLPGPRGLPGDK-GKDGLPGQ 644

Query: 133 PPSPR-----------GSRQERG-ANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARG- 179
              P            GS    G   +PG  G +G  G      +P +   +  PG+ G 
Sbjct: 645 QGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGL 704

Query: 180 ---TDPPGRTLPAPLARPSTQ-----PGRRPGLGRAASPLGPRGAGVTG 220
               + PG   P P            PG+    G   SP  P   G TG
Sbjct: 705 VHLPELPG--FPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATG 751


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 62/204 (30%), Positives = 72/204 (35%), Gaps = 34/204 (16%)

Query: 46   PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPP 105
            PG    GPR  +  P     G    +  PG +   G      P     G    P P  P 
Sbjct: 1218 PGISPPGPRGKKGPP-----GPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPR 1272

Query: 106  GPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQE 165
            G  G    P     L+   G    PG PP P G         PG  G  GC G    Q+ 
Sbjct: 1273 GAPGPPGLPGSVDLLRGEPGDCGLPG-PPGPPGP-----PGPPGYKGFPGCDGKDG-QKG 1325

Query: 166  PTNFRGRP-------RPGARG-TDPPGRTLPAPLARPSTQPG---------RRPGLGRAA 208
            P  F G          PG +G   PPGR  P  L  P  +PG         R PGL  A 
Sbjct: 1326 PVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAP 1385

Query: 209  SPLGPRGA-GVTG----AGPATQG 227
               GP GA G+ G    +GP  +G
Sbjct: 1386 GMRGPEGAMGLPGMRGPSGPGCKG 1409



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 66/213 (30%), Positives = 75/213 (35%), Gaps = 44/213 (20%)

Query: 37   GSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGS 96
            G P D+ P PGP+  GPR     P L           PGS   +      +P    L G 
Sbjct: 1258 GPPGDQGP-PGPD--GPRGAPGPPGL-----------PGSVDLL----RGEPGDCGLPGP 1299

Query: 97   RGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANS----PGRSG 152
             GP    PPGP G   FP   G    + G    PG P  P G     G       PGR G
Sbjct: 1300 PGPPG--PPGPPGYKGFPGCDGK-DGQKGPVGFPG-PQGPHGFPGPPGEKGLPGPPGRKG 1355

Query: 153  ARGCGGAAALQQEPTNFRGRPR----PGARGTDPPGRTLPAPLARPSTQPGRR--PGL-- 204
              G  G       P +    PR    PGA G   P   +  P  R  + PG +  PGL  
Sbjct: 1356 PTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDG 1415

Query: 205  -----GRAASPLGPRGAGVTG-----AGPATQG 227
                 G   SP  P   G TG      GP   G
Sbjct: 1416 RRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPG 1448



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 59/195 (30%), Positives = 72/195 (36%), Gaps = 24/195 (12%)

Query: 46  PGPERRGPRPPQTIPTLFLA-GVFSETEAPGSSTHVGA----GNSSDPATSRLGGSRGPH 100
           PGP  +G   PQ  P L  + G       PG++   G     G+  DP     GG +G  
Sbjct: 685 PGP--KGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPG---FGGEKGSS 739

Query: 101 PTLPPGPAGSLVFPERRGSLQD----RLGRASRPGCP--PSPRGSRQERGANSPGRSGAR 154
           P  PPGP GS     ++G   D     LG   + G    P  +G R + G   PG  G  
Sbjct: 740 PVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGC--PGAEGPA 797

Query: 155 GCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPR 214
           G  G   L+           PG  G  PPG +          QPG     G   SP  P 
Sbjct: 798 GIPGFLGLKGPKGREGHAGFPGVPG--PPGHSCERGAPGIPGQPGLP---GYPGSPGAPG 852

Query: 215 GAGVTG-AGPATQGG 228
           G G  G  GP    G
Sbjct: 853 GKGQPGDVGPPGPAG 867



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 42/128 (32%), Positives = 48/128 (37%), Gaps = 20/128 (15%)

Query: 95   GSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPG-CPPSPRGSRQERGANSPGRSGA 153
            G+ G H   PPGP G          L+   G    PG  PP PRG +   G   PG SG 
Sbjct: 1190 GASGLHDVGPPGPVGI-------PGLKGERGDPGSPGISPPGPRGKKGPPG--PPGSSGP 1240

Query: 154  RGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGR------RPGLGRA 207
             G  GA    + P +      PG +G  PPG   P     P   PG        PG    
Sbjct: 1241 PGPAGATG--RAPKDIPDPGPPGDQG--PPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGL 1296

Query: 208  ASPLGPRG 215
              P GP G
Sbjct: 1297 PGPPGPPG 1304



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 64/233 (27%), Positives = 73/233 (31%), Gaps = 67/233 (28%)

Query: 46   PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTL-- 103
            PGP    P PP    +  L G       PG       G+   P  S + G+RGP      
Sbjct: 1023 PGP----PGPPGPPGSTGLRGFIGFPGLPGDQGE--PGSPGPPGFSGIDGARGPKGNKGD 1076

Query: 104  ------PPGPAGSLVFPERRGSLQDRLGRASRPGCP--PSPRGSRQERGANSPGRSGARG 155
                  PPGP G    P   G      G +   G P    PRGS    G   PG SG  G
Sbjct: 1077 PASHFGPPGPKGEPGSPGCPG----HFGASGEQGLPGIQGPRGSPGRPGP--PGSSGPPG 1130

Query: 156  CGGAAALQQEPTNFRGRPR----PGARGTD-PPGRTLPAPLARPSTQPGRR--------- 201
            C G   +       RG+P     PG RG    PG   P  +  PS  PG           
Sbjct: 1131 CPGDHGMP----GLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQK 1186

Query: 202  -------------------PGL--------GRAASPLGPRGAGVTGAGPATQG 227
                               PGL            SP GPRG       P + G
Sbjct: 1187 GTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSG 1239



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 48/147 (32%), Positives = 51/147 (34%), Gaps = 16/147 (10%)

Query: 70  ETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRAS 128
           E  APG     G  G    P     GG   P    PPGPAG    P     L  R G   
Sbjct: 829 ERGAPGIPGQPGLPGYPGSPGAP--GGKGQPGDVGPPGPAGMKGLP----GLPGRPGAHG 882

Query: 129 RPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLP 188
            PG P  P     +     PG  G RG  G      E      R +PGA G   PG    
Sbjct: 883 PPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGE------RGKPGAEGC--PGAKGE 934

Query: 189 APLARPSTQPGRRPGLGRAASPLGPRG 215
                 S  PG R GL  A   +GP G
Sbjct: 935 PGEKGMSGLPGDR-GLRGAKGAIGPPG 960



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 78/306 (25%), Positives = 96/306 (31%), Gaps = 78/306 (25%)

Query: 39   PLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSR 97
            P   + LPGP   GP+ P+ +P     G   E   PG+    GA G   +   S L G R
Sbjct: 892  PFGDDGLPGPP--GPKGPRGLPGF--PGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDR 947

Query: 98   GPHPTL----------------------PPGPAGSLVFPERRGS-----LQDRLGRASR- 129
            G                            PGP G   FP  RG      +Q R G   R 
Sbjct: 948  GLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRY 1007

Query: 130  -----------------PGCPPSPRGSRQERG----------------ANSPGRSGARGC 156
                             P  PP P GS   RG                   PG SG  G 
Sbjct: 1008 GPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGA 1067

Query: 157  GGAAALQQEPTNFRGRPRPGARGTDP--PG-------RTLPAPLARPSTQPGRRPGLGRA 207
             G    + +P +  G P P      P  PG       + LP  +  P   PGR    G +
Sbjct: 1068 RGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPG-IQGPRGSPGRPGPPGSS 1126

Query: 208  ASPLGPRGAGVTGAGPATQGGRDRGRWGRWVRRRVPCPLPGLR-PHERAGAALLATCRGN 266
              P  P   G+ G         D G  G      +P P PG++ P    G   L   +G 
Sbjct: 1127 GPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGP-PGIKGPSGSPGLNGLHGLKGQ 1185

Query: 267  APTPSA 272
              T  A
Sbjct: 1186 KGTKGA 1191



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 56/174 (32%), Positives = 66/174 (37%), Gaps = 43/174 (24%)

Query: 74  PGSSTHVG-AGNSSDPAT------SRLGGSRGPHPTLPPGPAG-----SLVFPERRGSLQ 121
           PGS    G AG   DP        +  GG   P P  PPG AG      L FP   G   
Sbjct: 583 PGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPG--- 639

Query: 122 DRLGRASRPGCP--PSPRGSRQERG------ANSPGRSGARGCGGAAALQQEPTNFRG-R 172
              G    PG P    P G + ++G         PGR G  G  G       P  F G +
Sbjct: 640 -ERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPG----PKGFPGPQ 694

Query: 173 PRPGARGTD----PPGRTLPAPLARPSTQPGRR-----PGLG--RAASPLGPRG 215
             PG  G+D     PG    A +  P   PG R     PG G  + +SP+GP G
Sbjct: 695 GAPGLSGSDGHKGRPGTPGTAEIPGP---PGFRGDMGDPGFGGEKGSSPVGPPG 745



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 46/145 (31%), Positives = 52/145 (35%), Gaps = 35/145 (24%)

Query: 99  PHPTLPPGPAGSLVFPERRGSLQDR-----LGRASRPGCPPSPRGSRQERGANSPGRSGA 153
           P P  PPGP G    P R+GS  D      LG    PG PP   G         PG+ GA
Sbjct: 496 PGPMGPPGPPG---LPGRQGSKGDLGLPGWLGTKGDPG-PPGAEGP-----PGLPGKHGA 546

Query: 154 RGCGGAAALQQEPTNFRGRPRPGARGTD-PPG----------------RTLPAPLARPST 196
            G  G    + +    R +   G RG D PPG                +  P P   P  
Sbjct: 547 SGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGP---PGD 603

Query: 197 QPGRRPGLGRAASPLGPRG-AGVTG 220
                PG      PLGP G AG  G
Sbjct: 604 HEDATPGGKGFPGPLGPPGKAGPVG 628



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 40/131 (30%), Positives = 48/131 (36%), Gaps = 35/131 (26%)

Query: 95  GSRGP-----HPTLP--PGPAGSLVFPERRGS--LQDRLGRASRPGCPPSPRGSRQERGA 145
           G +GP     H   P  PGP G       RG+  +  + G    PG P +P G  Q    
Sbjct: 804 GLKGPKGREGHAGFPGVPGPPGHSC---ERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDV 860

Query: 146 NSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRT-LPAPLARPSTQPGRRPGL 204
             PG +G +G  G               RPGA G  PPG   +P P            GL
Sbjct: 861 GPPGPAGMKGLPGLPG------------RPGAHG--PPGLPGIPGPFG--------DDGL 898

Query: 205 GRAASPLGPRG 215
                P GPRG
Sbjct: 899 PGPPGPKGPRG 909



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 42/146 (28%), Positives = 50/146 (34%), Gaps = 33/146 (22%)

Query: 95  GSRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANS-PGRSG 152
           GSRGP  P  P GP G L  P   G   ++  R  R   PP   G + ++G    PG  G
Sbjct: 62  GSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRG--PPGAAGDKGDKGPTGVPGFPG 119

Query: 153 ARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLG 212
             G  G                PG     PPG         P  +PG     G    P  
Sbjct: 120 LDGIPG---------------HPG-----PPG---------PRGKPGMSGHNGSRGDPGF 150

Query: 213 PRGAGVTGAGPATQGGRDRGRWGRWV 238
           P G G  G G       ++G  G  V
Sbjct: 151 PGGRGALGPGGPLGHPGEKGEKGNSV 176



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 49/179 (27%), Positives = 58/179 (32%), Gaps = 46/179 (25%)

Query: 74  PGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSL------------- 120
           PG     G G   +       G RG      PG  GS  FP  +G L             
Sbjct: 287 PGRKGESGIGAKGEKGIPGFPGPRGD-----PGSYGSPGFPGLKGELGLVGDPGLFGLIG 341

Query: 121 -QDRLGRASRPG------CPPSP-RGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGR 172
            +   G    PG       PP P +G   + G   PGR G  G  G       P    GR
Sbjct: 342 PKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPG--FPGRYGETGDVGPPG----PPGLLGR 395

Query: 173 PRPGARG-TDPPGRT-------LPAPL---ARPSTQPGRRPGLGRAASPLGPRGAGVTG 220
           P     G   PPG         LP       RP + PG+    G+  SP  P   G+ G
Sbjct: 396 PGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKP---GKPGSPGLPGAPGLQG 451


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
            sapiens]
          Length = 1690

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 63/199 (31%), Positives = 76/199 (38%), Gaps = 33/199 (16%)

Query: 46   PG-PERRGPRPPQTIPTLFLAGVFSETEAPGSST-HVGAGNSSDPATSRLGGSRG-PHPT 102
            PG P  RG +  +  P L   G      APG S   + AG   DP    L G RG P P 
Sbjct: 1218 PGKPGLRGQKGDRGFPGL--QGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPA 1275

Query: 103  LPPGPAGSLVFPERRGSLQDRLGRASRPGCP--PSPRGSRQERGANSPGRSGARGCGGAA 160
             PPGP G               G    PG P  P P+G + ++G   PG SG  G  G  
Sbjct: 1276 GPPGPPGP----------SSNQGDTGDPGFPGIPGPKGPKGDQGI--PGFSGLPGELGLK 1323

Query: 161  ALQQEPTNFRGRPRPGARGTDP-----PGRTLPAPLARPSTQPGRRPGLGRAASPLGPRG 215
             ++ EP  F G P       DP      G+  P   +     PG+ P       P GP G
Sbjct: 1324 GMRGEP-GFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLG 1382

Query: 216  -------AGVTGAGPATQG 227
                    G+TG  P  QG
Sbjct: 1383 LPGIDGIPGLTG-DPGAQG 1400



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 57/187 (30%), Positives = 72/187 (38%), Gaps = 37/187 (19%)

Query: 64   LAGVFSETEAPGSSTHVGA----------------------GNSSDPATSRLGGSRGPHP 101
            +AG+  E   PGSS H GA                      G +  P T    G+ GP  
Sbjct: 1133 VAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSI 1192

Query: 102  TLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAA 161
            T  PGPAG       +G     +G   +PG     RG + +RG   PG  G  G  GA  
Sbjct: 1193 TGVPGPAGLPGPKGEKGYPGIGIGAPGKPGL----RGQKGDRG--FPGLQGPAGLPGAPG 1246

Query: 162  LQQEPTNFRGRP----RPGARG-TDPPGRTLPAPLARPSTQPGRR--PGLGRAASPLGPR 214
            +   P+   G+P    RPG  G    PG   P     PS+  G    PG      P GP+
Sbjct: 1247 ISL-PSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPK 1305

Query: 215  G-AGVTG 220
            G  G+ G
Sbjct: 1306 GDQGIPG 1312



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 59/222 (26%), Positives = 76/222 (34%), Gaps = 46/222 (20%)

Query: 43  NPLPG-PERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA----------GNSSDP--A 89
           N +PG P + GPR P  +      G       PG   + G           G+  DP  A
Sbjct: 105 NGIPGHPGQPGPRGPPGLDGC--NGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLA 162

Query: 90  TSRLGGSRGPHPTLP-----PGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERG 144
                G +G  P LP      GP G+  FP   G      G    PG PP P G     G
Sbjct: 163 PGSFKGMKGD-PGLPGLDGITGPQGAPGFPGAVGPAGPP-GLQGPPG-PPGPLGPDGNMG 219

Query: 145 ANSPGRSGARGCGGAAALQQEPTN-----FRGRPR--------PGARG----TDPPGRTL 187
               G  G +G  G       P +     F G P+        PG +G    + PPG   
Sbjct: 220 LGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPG--- 276

Query: 188 PAPLARPSTQPGRR--PGLGRAASPLGPRGAGVTGAGPATQG 227
             P    + + G +   G+     P GP G+      P  QG
Sbjct: 277 -FPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQG 317



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 49/166 (29%), Positives = 64/166 (38%), Gaps = 30/166 (18%)

Query: 83   GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSP-----R 137
            G    P  S   G++G       G  G++ FP  +G    ++G +   G P +P      
Sbjct: 1081 GPKGQPGESGFKGTKGRD-----GLIGNIGFPGNKGE-DGKVGVSGDVGLPGAPGFPGVA 1134

Query: 138  GSRQERGANSPGRSGARGCGGAAALQQ--EPTNFRGRP-------RPGARGT-DPPGRTL 187
            G R E G   PG SG +G  G         P  F G P        PG +GT   PG ++
Sbjct: 1135 GMRGEPGL--PGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSI 1192

Query: 188  -----PAPLARPSTQPGRRPGLG-RAASPLGPRGAGVTGAGPATQG 227
                 PA L  P  + G  PG+G  A    G RG       P  QG
Sbjct: 1193 TGVPGPAGLPGPKGEKG-YPGIGIGAPGKPGLRGQKGDRGFPGLQG 1237



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 42/152 (27%), Positives = 56/152 (36%), Gaps = 20/152 (13%)

Query: 37   GSPLDRNPLPGPERRG-PRPPQTIPTLFLAGVFSETEAPGSSTHVGA----GNSSDPATS 91
            G+P ++     P   G P P + +  L+L G      + GS+   G     G +  P   
Sbjct: 938  GTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPP 997

Query: 92   RLGGSRGPHPTL--------PPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQER 143
             L G+ G    +        PPG  G    P  +GS     G    PG P    GS+  R
Sbjct: 998  GLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSS----GITGFPGMP-GESGSQGIR 1052

Query: 144  GANSPGRSGARGCGGAAALQQEPTNFRGRPRP 175
            G  SPG  GA G  G      +     G P P
Sbjct: 1053 G--SPGLPGASGLPGLKGDNGQTVEISGSPGP 1082



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 15/77 (19%)

Query: 104 PPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERG-ANSPGRSGARGCGGAAAL 162
           PPGP G +  P  +G+  DR              GS   +G A +PG  G  G  G    
Sbjct: 498 PPGPWGLIGLPGLKGARGDR--------------GSGGAQGPAGAPGLVGPLGPSGPKGK 543

Query: 163 QQEPTNFRGRPRPGARG 179
           + EP     +  PG RG
Sbjct: 544 KGEPILSTIQGMPGDRG 560



 Score = 28.5 bits (62), Expect = 8.6
 Identities = 45/169 (26%), Positives = 57/169 (33%), Gaps = 26/169 (15%)

Query: 74  PGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLV-FPERRGSLQDRLGRASRPGC 132
           PG     G G   +     L G +G HP  P  P   L   P  RG   D+ G+   PG 
Sbjct: 586 PGLPGDGGQGFPGEKGLPGLPGEKG-HPGPPGLPGNGLPGLPGPRGLPGDK-GKDGLPGQ 643

Query: 133 PPSPR-----------GSRQERG-ANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARG- 179
              P            GS    G   +PG  G +G  G      +P +   +  PG+ G 
Sbjct: 644 QGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGL 703

Query: 180 ---TDPPGRTLPAPLARPSTQ-----PGRRPGLGRAASPLGPRGAGVTG 220
               + PG   P P            PG+    G   SP  P   G TG
Sbjct: 704 VHLPELPG--FPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATG 750


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1751

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 66/216 (30%), Positives = 77/216 (35%), Gaps = 48/216 (22%)

Query: 39   PLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA----GNSSDPATSRLG 94
            P  +     P  RGP  P   P     G   E   PG     G     G   +P  + LG
Sbjct: 1193 PAQKGAKGEPGFRGPPGPYGRP-----GYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG 1247

Query: 95   -GSRG----PHPTLPPGPAGSLVFPERRGSLQDRLGRASRPG--CPPSPRGSRQERGANS 147
             G RG    P P  PPGP G+ V+     +   R G    PG   PP P+G++ E G   
Sbjct: 1248 FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPG 1307

Query: 148  P----------------GRSGARGCGGAAALQQEP--TNFRGRPRPGARGTDPPGRT--- 186
            P                G  G RG  G    + EP    F G   PG  G  PPG     
Sbjct: 1308 PPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPG--PPGPRGYP 1365

Query: 187  -LPAPLARP-STQPGRRPGLGRAASPLGPRGAGVTG 220
             +P P       QPG  PG      P GP G G  G
Sbjct: 1366 GIPGPKGESIRGQPG-PPG------PQGPPGIGYEG 1394



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 50/155 (32%), Positives = 64/155 (41%), Gaps = 22/155 (14%)

Query: 83   GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGC-----PPSPR 137
            G   DP    +G    P P  PPGP   +   E+ GS+    G   RPG      P  P+
Sbjct: 1102 GEKGDPGKDGVGQPGLPGPPGPPGPV--VYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPK 1159

Query: 138  ---GSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARP 194
               GS+ ERG  SPG  G +G  G  ++        G  + GA+G +P  R  P P  RP
Sbjct: 1160 GNLGSKGERG--SPGPKGEKGEPG--SIFSPDGGALGPAQKGAKG-EPGFRGPPGPYGRP 1214

Query: 195  STQ-----PGR--RPGLGRAASPLGPRGAGVTGAG 222
              +     PGR  RPG+       G  G    G G
Sbjct: 1215 GYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFG 1249



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 62/212 (29%), Positives = 71/212 (33%), Gaps = 40/212 (18%)

Query: 33   FLILGSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSR 92
            F + G P    P PGP    P PP T   ++ + VF+E+  PG       GN   P    
Sbjct: 1248 FGMRGMPGPPGP-PGP----PGPPGT--PVYDSNVFAESSRPGPPGL--PGNQGPPGPKG 1298

Query: 93   LGGSRGPHPTLPPGPAGSLVFP------ERRGSLQDR-----LGRASRPGC--------- 132
              G  GP     PGP G   F       E +G   DR      G    PG          
Sbjct: 1299 AKGEVGP-----PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLP 1353

Query: 133  -PPSPRGSRQERGANSPGRSGARGCGGAAALQQEP-TNFRGRPRPGARGTDPPGRTLPAP 190
             PP P G R   G   P     RG  G    Q  P   + GR  P      PPG   P  
Sbjct: 1354 GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPG----PPGPPGPPS 1409

Query: 191  LARPSTQPGRRPGLGRAASPLGPRGAGVTGAG 222
               P  Q    PG      P GP G     +G
Sbjct: 1410 FPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1441



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/214 (29%), Positives = 77/214 (35%), Gaps = 52/214 (24%)

Query: 46   PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSR----LGGSRGPH- 100
            PGP  R   P +T       G   E  APG   H G+  +  PA +R    L G+ GP  
Sbjct: 955  PGPPGREGPPGRTGQK----GSLGEAGAPG---HKGSKGAPGPAGARGESGLAGAPGPAG 1007

Query: 101  ------PTLPPGPAGSLVFPERRGS-------LQDRLGRASRPGCP--------PSPRGS 139
                  P  PPGP     F +  GS        +   G    PG P        P   G+
Sbjct: 1008 PPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGA 1067

Query: 140  RQERGANS-PGRSGARGCGGAAALQQEPTNFRG----RPRPGARGTDPPGRT----LPAP 190
            + E GA+  PG  G  G  G A   Q P   RG    +  PG  G   PG       P P
Sbjct: 1068 KGEVGADGVPGFPGLPGREGIAG-PQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGP 1126

Query: 191  LARPSTQPGR---------RPGLGRAASPLGPRG 215
            +   S Q G          RPG      P GP+G
Sbjct: 1127 VVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG 1160



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 63/194 (32%), Positives = 72/194 (37%), Gaps = 38/194 (19%)

Query: 37   GSPLDRNPL-----PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHV---GAGNSSDP 88
            G+P D  P      PG   RGP  PQ  P     G    +      T +   G+G   D 
Sbjct: 841  GTPGDVGPKGDKGDPGVGERGPPGPQGPP-----GPPGPSFRHDKLTFIDMEGSGFGGD- 894

Query: 89   ATSRLGGSRG-PHPTLPPGPAGSLVFPERRG-SLQDRLGRASRPGCP-----------PS 135
                L G RG P P  PPG  G    P R G +  D  G A  PG P           P 
Sbjct: 895  -LEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 953

Query: 136  PRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRP-GARG----TDPPGRTLPAP 190
            P G     G   PGR+G +G  G A       + +G P P GARG       PG   P  
Sbjct: 954  PPGPPGREGP--PGRTGQKGSLGEAGAPGHKGS-KGAPGPAGARGESGLAGAPGPAGPPG 1010

Query: 191  LARPSTQPGRRPGL 204
               P   PG  PGL
Sbjct: 1011 PPGPPGPPG--PGL 1022



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 52/192 (27%), Positives = 69/192 (35%), Gaps = 35/192 (18%)

Query: 54  RPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGS---RGPHP---TLPPGP 107
           R PQ  P   L     +++     +  G G++ +      G +   R P P   T PP  
Sbjct: 642 RDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLA 701

Query: 108 AGSLVFPERRGSLQDR-----LGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAAL 162
            GS     R   ++++     LG  + PG   S   S  +    +PG  G    GG    
Sbjct: 702 GGSSTEDSRSEEVEEQTTVASLGAQTLPG---SDSVSTWDGSVRTPG--GRVKEGGLKGQ 756

Query: 163 QQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGA- 221
           + EP    G P P  R   P    LP P           PGL    SPLGP G  +    
Sbjct: 757 KGEP----GVPGPPGRAGPPGSPCLPGP-----------PGLPCPVSPLGPAGPALQTVP 801

Query: 222 ---GPATQGGRD 230
              GP    GRD
Sbjct: 802 GPQGPPGPPGRD 813



 Score = 35.8 bits (81), Expect = 0.054
 Identities = 57/215 (26%), Positives = 68/215 (31%), Gaps = 61/215 (28%)

Query: 45  LPGPE-RRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTL 103
           +PGP  R GP     +P             PG    V     + PA   + G +GP    
Sbjct: 762 VPGPPGRAGPPGSPCLPG-----------PPGLPCPVSPLGPAGPALQTVPGPQGP---- 806

Query: 104 PPGPAGSLVFPERRGSLQD--------RLGRASRPGCP--PSPRGSRQERGANSPGRSGA 153
            PGP G    P R G   D          G    PG P    P+G + + G    G  G 
Sbjct: 807 -PGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGP 865

Query: 154 R-----------------------GCGGAAALQQEPTNFRGRP-RPGARG-TDPPGR--- 185
           +                       G GG     + P  F G P  PG  G    PGR   
Sbjct: 866 QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGV 925

Query: 186 ---TLPAPLARPSTQPGRR--PGLGRAASPLGPRG 215
               +P P   P   PGR   PG      P GP G
Sbjct: 926 NSSDVPGPAGLPGV-PGREGPPGFPGLPGPPGPPG 959


>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1336

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 66/216 (30%), Positives = 77/216 (35%), Gaps = 48/216 (22%)

Query: 39  PLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA----GNSSDPATSRLG 94
           P  +     P  RGP  P   P     G   E   PG     G     G   +P  + LG
Sbjct: 778 PAQKGAKGEPGFRGPPGPYGRP-----GYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG 832

Query: 95  -GSRG----PHPTLPPGPAGSLVFPERRGSLQDRLGRASRPG--CPPSPRGSRQERGANS 147
            G RG    P P  PPGP G+ V+     +   R G    PG   PP P+G++ E G   
Sbjct: 833 FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPG 892

Query: 148 P----------------GRSGARGCGGAAALQQEP--TNFRGRPRPGARGTDPPGRT--- 186
           P                G  G RG  G    + EP    F G   PG  G  PPG     
Sbjct: 893 PPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPG--PPGPRGYP 950

Query: 187 -LPAPLARP-STQPGRRPGLGRAASPLGPRGAGVTG 220
            +P P       QPG  PG      P GP G G  G
Sbjct: 951 GIPGPKGESIRGQPG-PPG------PQGPPGIGYEG 979



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 50/155 (32%), Positives = 64/155 (41%), Gaps = 22/155 (14%)

Query: 83  GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGC-----PPSPR 137
           G   DP    +G    P P  PPGP   +   E+ GS+    G   RPG      P  P+
Sbjct: 687 GEKGDPGKDGVGQPGLPGPPGPPGPV--VYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPK 744

Query: 138 ---GSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARP 194
              GS+ ERG  SPG  G +G  G  ++        G  + GA+G +P  R  P P  RP
Sbjct: 745 GNLGSKGERG--SPGPKGEKGEPG--SIFSPDGGALGPAQKGAKG-EPGFRGPPGPYGRP 799

Query: 195 STQ-----PGR--RPGLGRAASPLGPRGAGVTGAG 222
             +     PGR  RPG+       G  G    G G
Sbjct: 800 GYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFG 834



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 62/212 (29%), Positives = 71/212 (33%), Gaps = 40/212 (18%)

Query: 33   FLILGSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSR 92
            F + G P    P PGP    P PP T   ++ + VF+E+  PG       GN   P    
Sbjct: 833  FGMRGMPGPPGP-PGP----PGPPGT--PVYDSNVFAESSRPGPPGL--PGNQGPPGPKG 883

Query: 93   LGGSRGPHPTLPPGPAGSLVFP------ERRGSLQDR-----LGRASRPGC--------- 132
              G  GP     PGP G   F       E +G   DR      G    PG          
Sbjct: 884  AKGEVGP-----PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLP 938

Query: 133  -PPSPRGSRQERGANSPGRSGARGCGGAAALQQEP-TNFRGRPRPGARGTDPPGRTLPAP 190
             PP P G R   G   P     RG  G    Q  P   + GR  P      PPG   P  
Sbjct: 939  GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPG----PPGPPGPPS 994

Query: 191  LARPSTQPGRRPGLGRAASPLGPRGAGVTGAG 222
               P  Q    PG      P GP G     +G
Sbjct: 995  FPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1026



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/214 (29%), Positives = 77/214 (35%), Gaps = 52/214 (24%)

Query: 46  PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSR----LGGSRGPH- 100
           PGP  R   P +T       G   E  APG   H G+  +  PA +R    L G+ GP  
Sbjct: 540 PGPPGREGPPGRTGQK----GSLGEAGAPG---HKGSKGAPGPAGARGESGLAGAPGPAG 592

Query: 101 ------PTLPPGPAGSLVFPERRGS-------LQDRLGRASRPGCP--------PSPRGS 139
                 P  PPGP     F +  GS        +   G    PG P        P   G+
Sbjct: 593 PPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGA 652

Query: 140 RQERGANS-PGRSGARGCGGAAALQQEPTNFRG----RPRPGARGTDPPGRT----LPAP 190
           + E GA+  PG  G  G  G A   Q P   RG    +  PG  G   PG       P P
Sbjct: 653 KGEVGADGVPGFPGLPGREGIAG-PQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGP 711

Query: 191 LARPSTQPGR---------RPGLGRAASPLGPRG 215
           +   S Q G          RPG      P GP+G
Sbjct: 712 VVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG 745



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 63/194 (32%), Positives = 72/194 (37%), Gaps = 38/194 (19%)

Query: 37  GSPLDRNPL-----PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHV---GAGNSSDP 88
           G+P D  P      PG   RGP  PQ  P     G    +      T +   G+G   D 
Sbjct: 426 GTPGDVGPKGDKGDPGVGERGPPGPQGPP-----GPPGPSFRHDKLTFIDMEGSGFGGD- 479

Query: 89  ATSRLGGSRG-PHPTLPPGPAGSLVFPERRG-SLQDRLGRASRPGCP-----------PS 135
               L G RG P P  PPG  G    P R G +  D  G A  PG P           P 
Sbjct: 480 -LEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 538

Query: 136 PRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRP-GARG----TDPPGRTLPAP 190
           P G     G   PGR+G +G  G A       + +G P P GARG       PG   P  
Sbjct: 539 PPGPPGREGP--PGRTGQKGSLGEAGAPGHKGS-KGAPGPAGARGESGLAGAPGPAGPPG 595

Query: 191 LARPSTQPGRRPGL 204
              P   PG  PGL
Sbjct: 596 PPGPPGPPG--PGL 607



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 52/192 (27%), Positives = 69/192 (35%), Gaps = 35/192 (18%)

Query: 54  RPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGS---RGPHP---TLPPGP 107
           R PQ  P   L     +++     +  G G++ +      G +   R P P   T PP  
Sbjct: 227 RDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLA 286

Query: 108 AGSLVFPERRGSLQDR-----LGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAAL 162
            GS     R   ++++     LG  + PG   S   S  +    +PG  G    GG    
Sbjct: 287 GGSSTEDSRSEEVEEQTTVASLGAQTLPG---SDSVSTWDGSVRTPG--GRVKEGGLKGQ 341

Query: 163 QQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGA- 221
           + EP    G P P  R   P    LP P           PGL    SPLGP G  +    
Sbjct: 342 KGEP----GVPGPPGRAGPPGSPCLPGP-----------PGLPCPVSPLGPAGPALQTVP 386

Query: 222 ---GPATQGGRD 230
              GP    GRD
Sbjct: 387 GPQGPPGPPGRD 398



 Score = 35.8 bits (81), Expect = 0.054
 Identities = 57/215 (26%), Positives = 68/215 (31%), Gaps = 61/215 (28%)

Query: 45  LPGPE-RRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTL 103
           +PGP  R GP     +P             PG    V     + PA   + G +GP    
Sbjct: 347 VPGPPGRAGPPGSPCLPG-----------PPGLPCPVSPLGPAGPALQTVPGPQGP---- 391

Query: 104 PPGPAGSLVFPERRGSLQD--------RLGRASRPGCP--PSPRGSRQERGANSPGRSGA 153
            PGP G    P R G   D          G    PG P    P+G + + G    G  G 
Sbjct: 392 -PGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGP 450

Query: 154 R-----------------------GCGGAAALQQEPTNFRGRP-RPGARG-TDPPGR--- 185
           +                       G GG     + P  F G P  PG  G    PGR   
Sbjct: 451 QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGV 510

Query: 186 ---TLPAPLARPSTQPGRR--PGLGRAASPLGPRG 215
               +P P   P   PGR   PG      P GP G
Sbjct: 511 NSSDVPGPAGLPGV-PGREGPPGFPGLPGPPGPPG 544


>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1516

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 66/216 (30%), Positives = 77/216 (35%), Gaps = 48/216 (22%)

Query: 39   PLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA----GNSSDPATSRLG 94
            P  +     P  RGP  P   P     G   E   PG     G     G   +P  + LG
Sbjct: 958  PAQKGAKGEPGFRGPPGPYGRP-----GYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG 1012

Query: 95   -GSRG----PHPTLPPGPAGSLVFPERRGSLQDRLGRASRPG--CPPSPRGSRQERGANS 147
             G RG    P P  PPGP G+ V+     +   R G    PG   PP P+G++ E G   
Sbjct: 1013 FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPG 1072

Query: 148  P----------------GRSGARGCGGAAALQQEP--TNFRGRPRPGARGTDPPGRT--- 186
            P                G  G RG  G    + EP    F G   PG  G  PPG     
Sbjct: 1073 PPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPG--PPGPRGYP 1130

Query: 187  -LPAPLARP-STQPGRRPGLGRAASPLGPRGAGVTG 220
             +P P       QPG  PG      P GP G G  G
Sbjct: 1131 GIPGPKGESIRGQPG-PPG------PQGPPGIGYEG 1159



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 50/155 (32%), Positives = 64/155 (41%), Gaps = 22/155 (14%)

Query: 83   GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGC-----PPSPR 137
            G   DP    +G    P P  PPGP   +   E+ GS+    G   RPG      P  P+
Sbjct: 867  GEKGDPGKDGVGQPGLPGPPGPPGPV--VYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPK 924

Query: 138  ---GSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARP 194
               GS+ ERG  SPG  G +G  G  ++        G  + GA+G +P  R  P P  RP
Sbjct: 925  GNLGSKGERG--SPGPKGEKGEPG--SIFSPDGGALGPAQKGAKG-EPGFRGPPGPYGRP 979

Query: 195  STQ-----PGR--RPGLGRAASPLGPRGAGVTGAG 222
              +     PGR  RPG+       G  G    G G
Sbjct: 980  GYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFG 1014



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 62/212 (29%), Positives = 71/212 (33%), Gaps = 40/212 (18%)

Query: 33   FLILGSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSR 92
            F + G P    P PGP    P PP T   ++ + VF+E+  PG       GN   P    
Sbjct: 1013 FGMRGMPGPPGP-PGP----PGPPGT--PVYDSNVFAESSRPGPPGL--PGNQGPPGPKG 1063

Query: 93   LGGSRGPHPTLPPGPAGSLVFP------ERRGSLQDR-----LGRASRPGC--------- 132
              G  GP     PGP G   F       E +G   DR      G    PG          
Sbjct: 1064 AKGEVGP-----PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLP 1118

Query: 133  -PPSPRGSRQERGANSPGRSGARGCGGAAALQQEP-TNFRGRPRPGARGTDPPGRTLPAP 190
             PP P G R   G   P     RG  G    Q  P   + GR  P      PPG   P  
Sbjct: 1119 GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPG----PPGPPGPPS 1174

Query: 191  LARPSTQPGRRPGLGRAASPLGPRGAGVTGAG 222
               P  Q    PG      P GP G     +G
Sbjct: 1175 FPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1206



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/214 (29%), Positives = 77/214 (35%), Gaps = 52/214 (24%)

Query: 46  PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSR----LGGSRGPH- 100
           PGP  R   P +T       G   E  APG   H G+  +  PA +R    L G+ GP  
Sbjct: 720 PGPPGREGPPGRTGQK----GSLGEAGAPG---HKGSKGAPGPAGARGESGLAGAPGPAG 772

Query: 101 ------PTLPPGPAGSLVFPERRGS-------LQDRLGRASRPGCP--------PSPRGS 139
                 P  PPGP     F +  GS        +   G    PG P        P   G+
Sbjct: 773 PPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGA 832

Query: 140 RQERGANS-PGRSGARGCGGAAALQQEPTNFRG----RPRPGARGTDPPGRT----LPAP 190
           + E GA+  PG  G  G  G A   Q P   RG    +  PG  G   PG       P P
Sbjct: 833 KGEVGADGVPGFPGLPGREGIAG-PQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGP 891

Query: 191 LARPSTQPGR---------RPGLGRAASPLGPRG 215
           +   S Q G          RPG      P GP+G
Sbjct: 892 VVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG 925



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 63/194 (32%), Positives = 72/194 (37%), Gaps = 38/194 (19%)

Query: 37  GSPLDRNPL-----PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHV---GAGNSSDP 88
           G+P D  P      PG   RGP  PQ  P     G    +      T +   G+G   D 
Sbjct: 606 GTPGDVGPKGDKGDPGVGERGPPGPQGPP-----GPPGPSFRHDKLTFIDMEGSGFGGD- 659

Query: 89  ATSRLGGSRG-PHPTLPPGPAGSLVFPERRG-SLQDRLGRASRPGCP-----------PS 135
               L G RG P P  PPG  G    P R G +  D  G A  PG P           P 
Sbjct: 660 -LEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 718

Query: 136 PRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRP-GARG----TDPPGRTLPAP 190
           P G     G   PGR+G +G  G A       + +G P P GARG       PG   P  
Sbjct: 719 PPGPPGREGP--PGRTGQKGSLGEAGAPGHKGS-KGAPGPAGARGESGLAGAPGPAGPPG 775

Query: 191 LARPSTQPGRRPGL 204
              P   PG  PGL
Sbjct: 776 PPGPPGPPG--PGL 787



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 52/192 (27%), Positives = 69/192 (35%), Gaps = 35/192 (18%)

Query: 54  RPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGS---RGPHP---TLPPGP 107
           R PQ  P   L     +++     +  G G++ +      G +   R P P   T PP  
Sbjct: 407 RDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLA 466

Query: 108 AGSLVFPERRGSLQDR-----LGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAAL 162
            GS     R   ++++     LG  + PG   S   S  +    +PG  G    GG    
Sbjct: 467 GGSSTEDSRSEEVEEQTTVASLGAQTLPG---SDSVSTWDGSVRTPG--GRVKEGGLKGQ 521

Query: 163 QQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGA- 221
           + EP    G P P  R   P    LP P           PGL    SPLGP G  +    
Sbjct: 522 KGEP----GVPGPPGRAGPPGSPCLPGP-----------PGLPCPVSPLGPAGPALQTVP 566

Query: 222 ---GPATQGGRD 230
              GP    GRD
Sbjct: 567 GPQGPPGPPGRD 578



 Score = 35.8 bits (81), Expect = 0.054
 Identities = 57/215 (26%), Positives = 68/215 (31%), Gaps = 61/215 (28%)

Query: 45  LPGPE-RRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTL 103
           +PGP  R GP     +P             PG    V     + PA   + G +GP    
Sbjct: 527 VPGPPGRAGPPGSPCLPG-----------PPGLPCPVSPLGPAGPALQTVPGPQGP---- 571

Query: 104 PPGPAGSLVFPERRGSLQD--------RLGRASRPGCP--PSPRGSRQERGANSPGRSGA 153
            PGP G    P R G   D          G    PG P    P+G + + G    G  G 
Sbjct: 572 -PGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGP 630

Query: 154 R-----------------------GCGGAAALQQEPTNFRGRP-RPGARG-TDPPGR--- 185
           +                       G GG     + P  F G P  PG  G    PGR   
Sbjct: 631 QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGV 690

Query: 186 ---TLPAPLARPSTQPGRR--PGLGRAASPLGPRG 215
               +P P   P   PGR   PG      P GP G
Sbjct: 691 NSSDVPGPAGLPGV-PGREGPPGFPGLPGPPGPPG 724


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 65/210 (30%), Positives = 76/210 (36%), Gaps = 50/210 (23%)

Query: 39   PLDRNPLPGP-ERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGS 96
            P   N  PGP  +RGP           AG      +PGS    G  G   DP      G 
Sbjct: 1221 PTGENGPPGPLGKRGP-----------AG------SPGSEGRQGGKGAKGDPGAIGAPGK 1263

Query: 97   RGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGC-----PPSPRGSRQERGANSPGRS 151
             GP    P GPAG    P+    L   +G+  RPG      PP P G         PG  
Sbjct: 1264 TGP--VGPAGPAGK-PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGP--------PGLP 1312

Query: 152  GARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQ-------------P 198
            G RG  GA   +  P        PG +G +   R LP P   P  +             P
Sbjct: 1313 GLRGDAGAKGEKGHPGLIGLIGPPGEQG-EKGDRGLPGPQGSPGQKGEMGIPGASGPIGP 1371

Query: 199  GRRPGLGRAASPLGPRGAGVTGAGPATQGG 228
            G  PGL   A P G +GA   G GP  + G
Sbjct: 1372 GGPPGLPGPAGPKGAKGATGPG-GPKGEKG 1400



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 65/210 (30%), Positives = 74/210 (35%), Gaps = 39/210 (18%)

Query: 46   PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPP 105
            PGP   GP  P   P    AG   E  A G   H GA    D  T    G        PP
Sbjct: 1021 PGPP--GPIGPVGQPGA--AGADGEPGARGPQGHFGA--KGDEGTRGFNG--------PP 1066

Query: 106  GPAGSLVFPERRGSLQDR--LGRASRPGCPPSPRGSRQERGANS-------------PGR 150
            GP G    P   G   +   +G    PG PP PRG     GA+              PG 
Sbjct: 1067 GPIGLQGLPGPSGEKGETGDVGPMGPPG-PPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1125

Query: 151  SGARGCGGAAALQQEPTNFRGRPRPGARG-TDPPGRTLPAPLARPSTQPGRRPGLGRAAS 209
             G  G  G+  +Q EP     R   G +G +  PG   P     P+   G +   G    
Sbjct: 1126 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF 1185

Query: 210  P--LGPRGAGVTGAGPATQGGR--DRGRWG 235
            P   GP G G    GP  Q G   DRG  G
Sbjct: 1186 PGDPGPPGEG----GPRGQDGAKGDRGEDG 1211



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 66/260 (25%), Positives = 86/260 (33%), Gaps = 78/260 (30%)

Query: 41  DRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPH 100
           +R P     +RGPR           G   ++ A G+S   G G    P    L G +GP+
Sbjct: 753 ERGPTGPRGQRGPR-----------GATGKSGAKGTSG--GDGPHGPPGERGLPGPQGPN 799

Query: 101 ----PTLPPGPAGSLVFPERRGS-----LQDRLGRASRPGC------------------- 132
               P  PPGP G    P   G       Q + G    PG                    
Sbjct: 800 GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 859

Query: 133 -PPSPRGSRQERGA-------------NSPGRSGARGCGGAAALQQEPTNFRGRPRPGAR 178
            PP P G +   G               +PG+ G  G  G    +  P    G   PG +
Sbjct: 860 GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG---PGLK 916

Query: 179 GTD----PPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGR----D 230
           G +    PPG         P+  PG R G   +  P+GP G       P   G +    +
Sbjct: 917 GNEGPSGPPG---------PAGSPGER-GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE 966

Query: 231 RGRWGRWVRRRV--PCPLPG 248
           +G  G   R  V  P  LPG
Sbjct: 967 KGPIGPTGRDGVQGPVGLPG 986



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 55/193 (28%), Positives = 66/193 (34%), Gaps = 49/193 (25%)

Query: 66  GVFSETEAPGSSTHVGA----GNSSDPATSRLGGSRGPH----PTLPPGPAGSLVFPERR 117
           G   E   PG    +G     G    P +    G  GP     PT  PGP G        
Sbjct: 650 GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG-------- 701

Query: 118 GSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAAL--------QQEPTNF 169
             L    G+   PG P  P     +     PG  GA G  GA  L        ++ PT  
Sbjct: 702 --LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP 759

Query: 170 RGRPRP-------GARGTD-------PPG-RTLPAPLARPSTQPGRRPGLGRAASPLGPR 214
           RG+  P       GA+GT        PPG R LP P   P+  PG +        P GP 
Sbjct: 760 RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG-PNGFPGPK-------GPPGPP 811

Query: 215 GAGVTGAGPATQG 227
           G       P  +G
Sbjct: 812 GKDGLPGHPGQRG 824



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 65/221 (29%), Positives = 76/221 (34%), Gaps = 51/221 (23%)

Query: 45  LPGPER----RGPRPPQTIPTLFLAGVFSETEAPGSSTHVG-AGNSSDPATSRLGGSRGP 99
           LPGP+      G + PQ  P L           PGS    G  G    P T    G++GP
Sbjct: 573 LPGPQGAIGPHGEKGPQGKPGL--------PGMPGSDGPPGHPGKEGPPGTK---GNQGP 621

Query: 100 HPTLPPGPAGSLVFPERRG--------SLQDRLGRASRPGCP--------------PSPR 137
                 GP G L +P  RG         L+   G     G P                  
Sbjct: 622 S-----GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 676

Query: 138 GSRQERGANSP-GRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAP-LARPS 195
           GSR E G   P GR+G  G  G   L  E         PG  G   P  +L  P     S
Sbjct: 677 GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGAS 736

Query: 196 TQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGR 236
            + G R GL   + P G RG      GP  Q G  RG  G+
Sbjct: 737 GEKGAR-GLSGKSGPRGERGP----TGPRGQRG-PRGATGK 771


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 65/210 (30%), Positives = 76/210 (36%), Gaps = 50/210 (23%)

Query: 39   PLDRNPLPGP-ERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGS 96
            P   N  PGP  +RGP           AG      +PGS    G  G   DP      G 
Sbjct: 1200 PTGENGPPGPLGKRGP-----------AG------SPGSEGRQGGKGAKGDPGAIGAPGK 1242

Query: 97   RGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGC-----PPSPRGSRQERGANSPGRS 151
             GP    P GPAG    P+    L   +G+  RPG      PP P G         PG  
Sbjct: 1243 TGP--VGPAGPAGK-PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGP--------PGLP 1291

Query: 152  GARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQ-------------P 198
            G RG  GA   +  P        PG +G +   R LP P   P  +             P
Sbjct: 1292 GLRGDAGAKGEKGHPGLIGLIGPPGEQG-EKGDRGLPGPQGSPGQKGEMGIPGASGPIGP 1350

Query: 199  GRRPGLGRAASPLGPRGAGVTGAGPATQGG 228
            G  PGL   A P G +GA   G GP  + G
Sbjct: 1351 GGPPGLPGPAGPKGAKGATGPG-GPKGEKG 1379



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 65/210 (30%), Positives = 74/210 (35%), Gaps = 39/210 (18%)

Query: 46   PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPP 105
            PGP   GP  P   P    AG   E  A G   H GA    D  T    G        PP
Sbjct: 1000 PGPP--GPIGPVGQPGA--AGADGEPGARGPQGHFGA--KGDEGTRGFNG--------PP 1045

Query: 106  GPAGSLVFPERRGSLQDR--LGRASRPGCPPSPRGSRQERGANS-------------PGR 150
            GP G    P   G   +   +G    PG PP PRG     GA+              PG 
Sbjct: 1046 GPIGLQGLPGPSGEKGETGDVGPMGPPG-PPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1104

Query: 151  SGARGCGGAAALQQEPTNFRGRPRPGARG-TDPPGRTLPAPLARPSTQPGRRPGLGRAAS 209
             G  G  G+  +Q EP     R   G +G +  PG   P     P+   G +   G    
Sbjct: 1105 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF 1164

Query: 210  P--LGPRGAGVTGAGPATQGGR--DRGRWG 235
            P   GP G G    GP  Q G   DRG  G
Sbjct: 1165 PGDPGPPGEG----GPRGQDGAKGDRGEDG 1190



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 66/260 (25%), Positives = 86/260 (33%), Gaps = 78/260 (30%)

Query: 41  DRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPH 100
           +R P     +RGPR           G   ++ A G+S   G G    P    L G +GP+
Sbjct: 732 ERGPTGPRGQRGPR-----------GATGKSGAKGTSG--GDGPHGPPGERGLPGPQGPN 778

Query: 101 ----PTLPPGPAGSLVFPERRGS-----LQDRLGRASRPGC------------------- 132
               P  PPGP G    P   G       Q + G    PG                    
Sbjct: 779 GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 838

Query: 133 -PPSPRGSRQERGA-------------NSPGRSGARGCGGAAALQQEPTNFRGRPRPGAR 178
            PP P G +   G               +PG+ G  G  G    +  P    G   PG +
Sbjct: 839 GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG---PGLK 895

Query: 179 GTD----PPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGR----D 230
           G +    PPG         P+  PG R G   +  P+GP G       P   G +    +
Sbjct: 896 GNEGPSGPPG---------PAGSPGER-GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE 945

Query: 231 RGRWGRWVRRRV--PCPLPG 248
           +G  G   R  V  P  LPG
Sbjct: 946 KGPIGPTGRDGVQGPVGLPG 965



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 55/193 (28%), Positives = 66/193 (34%), Gaps = 49/193 (25%)

Query: 66  GVFSETEAPGSSTHVGA----GNSSDPATSRLGGSRGPH----PTLPPGPAGSLVFPERR 117
           G   E   PG    +G     G    P +    G  GP     PT  PGP G        
Sbjct: 629 GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG-------- 680

Query: 118 GSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAAL--------QQEPTNF 169
             L    G+   PG P  P     +     PG  GA G  GA  L        ++ PT  
Sbjct: 681 --LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP 738

Query: 170 RGRPRP-------GARGTD-------PPG-RTLPAPLARPSTQPGRRPGLGRAASPLGPR 214
           RG+  P       GA+GT        PPG R LP P   P+  PG +        P GP 
Sbjct: 739 RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG-PNGFPGPK-------GPPGPP 790

Query: 215 GAGVTGAGPATQG 227
           G       P  +G
Sbjct: 791 GKDGLPGHPGQRG 803



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 65/221 (29%), Positives = 76/221 (34%), Gaps = 51/221 (23%)

Query: 45  LPGPER----RGPRPPQTIPTLFLAGVFSETEAPGSSTHVG-AGNSSDPATSRLGGSRGP 99
           LPGP+      G + PQ  P L           PGS    G  G    P T    G++GP
Sbjct: 552 LPGPQGAIGPHGEKGPQGKPGL--------PGMPGSDGPPGHPGKEGPPGTK---GNQGP 600

Query: 100 HPTLPPGPAGSLVFPERRG--------SLQDRLGRASRPGCP--------------PSPR 137
                 GP G L +P  RG         L+   G     G P                  
Sbjct: 601 S-----GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 655

Query: 138 GSRQERGANSP-GRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAP-LARPS 195
           GSR E G   P GR+G  G  G   L  E         PG  G   P  +L  P     S
Sbjct: 656 GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGAS 715

Query: 196 TQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGR 236
            + G R GL   + P G RG      GP  Q G  RG  G+
Sbjct: 716 GEKGAR-GLSGKSGPRGERGP----TGPRGQRG-PRGATGK 750



 Score = 28.5 bits (62), Expect = 8.6
 Identities = 34/114 (29%), Positives = 38/114 (33%), Gaps = 19/114 (16%)

Query: 134 PSPRGSRQERGANS-PGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLA 192
           P  + SR  R  N  P    A G  G    + EP        PG     PPG   PA L 
Sbjct: 248 PQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLE----PGMLVEGPPGPEGPAGLI 303

Query: 193 RPS---------TQPGRRPGLGRAASP-----LGPRGAGVTGAGPATQGGRDRG 232
            P            PG R   GRA  P      GP G  +        GG D+G
Sbjct: 304 GPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG 357


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 65/210 (30%), Positives = 76/210 (36%), Gaps = 50/210 (23%)

Query: 39   PLDRNPLPGP-ERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGS 96
            P   N  PGP  +RGP           AG      +PGS    G  G   DP      G 
Sbjct: 1307 PTGENGPPGPLGKRGP-----------AG------SPGSEGRQGGKGAKGDPGAIGAPGK 1349

Query: 97   RGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGC-----PPSPRGSRQERGANSPGRS 151
             GP    P GPAG    P+    L   +G+  RPG      PP P G         PG  
Sbjct: 1350 TGP--VGPAGPAGK-PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGP--------PGLP 1398

Query: 152  GARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQ-------------P 198
            G RG  GA   +  P        PG +G +   R LP P   P  +             P
Sbjct: 1399 GLRGDAGAKGEKGHPGLIGLIGPPGEQG-EKGDRGLPGPQGSPGQKGEMGIPGASGPIGP 1457

Query: 199  GRRPGLGRAASPLGPRGAGVTGAGPATQGG 228
            G  PGL   A P G +GA   G GP  + G
Sbjct: 1458 GGPPGLPGPAGPKGAKGATGPG-GPKGEKG 1486



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 65/210 (30%), Positives = 74/210 (35%), Gaps = 39/210 (18%)

Query: 46   PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPHPTLPP 105
            PGP   GP  P   P    AG   E  A G   H GA    D  T    G        PP
Sbjct: 1107 PGPP--GPIGPVGQPGA--AGADGEPGARGPQGHFGA--KGDEGTRGFNG--------PP 1152

Query: 106  GPAGSLVFPERRGSLQDR--LGRASRPGCPPSPRGSRQERGANS-------------PGR 150
            GP G    P   G   +   +G    PG PP PRG     GA+              PG 
Sbjct: 1153 GPIGLQGLPGPSGEKGETGDVGPMGPPG-PPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1211

Query: 151  SGARGCGGAAALQQEPTNFRGRPRPGARG-TDPPGRTLPAPLARPSTQPGRRPGLGRAAS 209
             G  G  G+  +Q EP     R   G +G +  PG   P     P+   G +   G    
Sbjct: 1212 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF 1271

Query: 210  P--LGPRGAGVTGAGPATQGGR--DRGRWG 235
            P   GP G G    GP  Q G   DRG  G
Sbjct: 1272 PGDPGPPGEG----GPRGQDGAKGDRGEDG 1297



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 66/260 (25%), Positives = 86/260 (33%), Gaps = 78/260 (30%)

Query: 41   DRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGPH 100
            +R P     +RGPR           G   ++ A G+S   G G    P    L G +GP+
Sbjct: 839  ERGPTGPRGQRGPR-----------GATGKSGAKGTSG--GDGPHGPPGERGLPGPQGPN 885

Query: 101  ----PTLPPGPAGSLVFPERRGS-----LQDRLGRASRPGC------------------- 132
                P  PPGP G    P   G       Q + G    PG                    
Sbjct: 886  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 945

Query: 133  -PPSPRGSRQERGA-------------NSPGRSGARGCGGAAALQQEPTNFRGRPRPGAR 178
             PP P G +   G               +PG+ G  G  G    +  P    G   PG +
Sbjct: 946  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG---PGLK 1002

Query: 179  GTD----PPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGR----D 230
            G +    PPG         P+  PG R G   +  P+GP G       P   G +    +
Sbjct: 1003 GNEGPSGPPG---------PAGSPGER-GAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE 1052

Query: 231  RGRWGRWVRRRV--PCPLPG 248
            +G  G   R  V  P  LPG
Sbjct: 1053 KGPIGPTGRDGVQGPVGLPG 1072



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 55/193 (28%), Positives = 66/193 (34%), Gaps = 49/193 (25%)

Query: 66  GVFSETEAPGSSTHVGA----GNSSDPATSRLGGSRGPH----PTLPPGPAGSLVFPERR 117
           G   E   PG    +G     G    P +    G  GP     PT  PGP G        
Sbjct: 736 GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG-------- 787

Query: 118 GSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAAL--------QQEPTNF 169
             L    G+   PG P  P     +     PG  GA G  GA  L        ++ PT  
Sbjct: 788 --LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP 845

Query: 170 RGRPRP-------GARGTD-------PPG-RTLPAPLARPSTQPGRRPGLGRAASPLGPR 214
           RG+  P       GA+GT        PPG R LP P   P+  PG +        P GP 
Sbjct: 846 RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG-PNGFPGPK-------GPPGPP 897

Query: 215 GAGVTGAGPATQG 227
           G       P  +G
Sbjct: 898 GKDGLPGHPGQRG 910



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 65/221 (29%), Positives = 76/221 (34%), Gaps = 51/221 (23%)

Query: 45  LPGPER----RGPRPPQTIPTLFLAGVFSETEAPGSSTHVG-AGNSSDPATSRLGGSRGP 99
           LPGP+      G + PQ  P L           PGS    G  G    P T    G++GP
Sbjct: 659 LPGPQGAIGPHGEKGPQGKPGL--------PGMPGSDGPPGHPGKEGPPGTK---GNQGP 707

Query: 100 HPTLPPGPAGSLVFPERRG--------SLQDRLGRASRPGCP--------------PSPR 137
                 GP G L +P  RG         L+   G     G P                  
Sbjct: 708 S-----GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 762

Query: 138 GSRQERGANSP-GRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAP-LARPS 195
           GSR E G   P GR+G  G  G   L  E         PG  G   P  +L  P     S
Sbjct: 763 GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGAS 822

Query: 196 TQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGR 236
            + G R GL   + P G RG      GP  Q G  RG  G+
Sbjct: 823 GEKGAR-GLSGKSGPRGERGP----TGPRGQRG-PRGATGK 857


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 58/205 (28%), Positives = 72/205 (35%), Gaps = 54/205 (26%)

Query: 46  PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRG------- 98
           PGP  RGP  P  +P   + G+  +   PG   + G G    P      G+ G       
Sbjct: 126 PGP--RGPPGPPGLPGHGIPGIKGK---PGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 180

Query: 99  ------------PHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCP--PSPRGSRQERG 144
                       P P  PPGP G              +G+   PG P  P P+G R  +G
Sbjct: 181 IGQKGEIGPMGIPGPQGPPGPHGL-----------PGIGKPGGPGLPGQPGPKGDRGPKG 229

Query: 145 ANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGT-DPPG-RTLPAPLARPSTQPGRRP 202
              PG  G RG          P   +G   PGA G   PPG    P P+  P      +P
Sbjct: 230 L--PGPQGLRG----------PKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGV---GKP 274

Query: 203 GLGRAASPLGPRGAGVTGAGPATQG 227
           G+     P GP G       P  QG
Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQG 299



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 62/200 (31%), Positives = 76/200 (38%), Gaps = 18/200 (9%)

Query: 41  DRNP--LPGPER-RGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSR 97
           DR P  LPGP+  RGP+  +        GV       G    VG      P  +   G +
Sbjct: 224 DRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQ 283

Query: 98  GP--HPTLP--PGPAGSLVFPERRGSLQ----DRLGRASRPGCPPSPRGSRQERGANSPG 149
           GP   P  P  PGP G +  P  +G        + G+   PG P  P G  ++     PG
Sbjct: 284 GPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPG 343

Query: 150 RSGARGCGGAAALQQEPTNFRGRPR-PGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAA 208
             G  G G        P   RG    PGA G  P G   P         PG  PGL    
Sbjct: 344 PPGLPGIGKPGF--PGPKGDRGMGGVPGALG--PRGEKGPIGAPGIGGPPGE-PGLPGIP 398

Query: 209 SPLGPRGAGVTGAGPATQGG 228
            P+GP GA +   GP  +GG
Sbjct: 399 GPMGPPGA-IGFPGPKGEGG 417



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 45/164 (27%), Positives = 61/164 (37%), Gaps = 26/164 (15%)

Query: 64  LAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQD 122
           + GV       G    +GA G    P    L G  GP      GP G++ FP  +G    
Sbjct: 364 MGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM-----GPPGAIGFPGPKGE--- 415

Query: 123 RLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDP 182
             G    P  PP P+G    +G   PG+ G  G  G   ++  P     +   G +G   
Sbjct: 416 --GGIVGPQGPPGPKGEPGLQGF--PGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGV-- 469

Query: 183 PGRTLPAPLARPSTQPGRR-----------PGLGRAASPLGPRG 215
           PG      L  P  +PG             PG+G  + P+GP G
Sbjct: 470 PGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPG 513


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 58/205 (28%), Positives = 72/205 (35%), Gaps = 54/205 (26%)

Query: 46  PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRG------- 98
           PGP  RGP  P  +P   + G+  +   PG   + G G    P      G+ G       
Sbjct: 126 PGP--RGPPGPPGLPGHGIPGIKGK---PGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 180

Query: 99  ------------PHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCP--PSPRGSRQERG 144
                       P P  PPGP G              +G+   PG P  P P+G R  +G
Sbjct: 181 IGQKGEIGPMGIPGPQGPPGPHGL-----------PGIGKPGGPGLPGQPGPKGDRGPKG 229

Query: 145 ANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGT-DPPG-RTLPAPLARPSTQPGRRP 202
              PG  G RG          P   +G   PGA G   PPG    P P+  P      +P
Sbjct: 230 L--PGPQGLRG----------PKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGV---GKP 274

Query: 203 GLGRAASPLGPRGAGVTGAGPATQG 227
           G+     P GP G       P  QG
Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQG 299



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 62/200 (31%), Positives = 76/200 (38%), Gaps = 18/200 (9%)

Query: 41  DRNP--LPGPER-RGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSR 97
           DR P  LPGP+  RGP+  +        GV       G    VG      P  +   G +
Sbjct: 224 DRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQ 283

Query: 98  GP--HPTLP--PGPAGSLVFPERRGSLQ----DRLGRASRPGCPPSPRGSRQERGANSPG 149
           GP   P  P  PGP G +  P  +G        + G+   PG P  P G  ++     PG
Sbjct: 284 GPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPG 343

Query: 150 RSGARGCGGAAALQQEPTNFRGRPR-PGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAA 208
             G  G G        P   RG    PGA G  P G   P         PG  PGL    
Sbjct: 344 PPGLPGIGKPGF--PGPKGDRGMGGVPGALG--PRGEKGPIGAPGIGGPPGE-PGLPGIP 398

Query: 209 SPLGPRGAGVTGAGPATQGG 228
            P+GP GA +   GP  +GG
Sbjct: 399 GPMGPPGA-IGFPGPKGEGG 417



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 45/164 (27%), Positives = 61/164 (37%), Gaps = 26/164 (15%)

Query: 64  LAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQD 122
           + GV       G    +GA G    P    L G  GP      GP G++ FP  +G    
Sbjct: 364 MGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM-----GPPGAIGFPGPKGE--- 415

Query: 123 RLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDP 182
             G    P  PP P+G    +G   PG+ G  G  G   ++  P     +   G +G   
Sbjct: 416 --GGIVGPQGPPGPKGEPGLQGF--PGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGV-- 469

Query: 183 PGRTLPAPLARPSTQPGRR-----------PGLGRAASPLGPRG 215
           PG      L  P  +PG             PG+G  + P+GP G
Sbjct: 470 PGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPG 513


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 74/249 (29%), Positives = 83/249 (33%), Gaps = 74/249 (29%)

Query: 37   GSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGS 96
            GSP    P   P  RGPR P+  P     G     E PG       G   DP  S   G 
Sbjct: 1326 GSPGLPGPRGDPGERGPRGPKGEPG--APGQVIGGEGPGL-----PGRKGDPGPSGPPGP 1378

Query: 97   RG----PHPTLPPGPAGSLVFPERRGSLQDR--------------LGRASRPGCPPS--- 135
            RG    P P  PPG  G+ +    +G   DR               G    PG P S   
Sbjct: 1379 RGPLGDPGPRGPPGLPGTAM----KGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGP 1434

Query: 136  -----PRGSRQERG------------ANSPGRSGARGCGGAAALQQEPTNFRGRPRP--- 175
                 P G + E+G              SPG  G RG  GA      P   RG P P   
Sbjct: 1435 QGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIG----PKGDRGFPGPLGE 1490

Query: 176  ----GARGTDPPG----RTLPAPLARPSTQ--------PGRRPGLGRAASPLGPRGAGVT 219
                G RG  PPG    R LP    RP  +         GR+   G    P  P   G  
Sbjct: 1491 AGEKGERG--PPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPA 1548

Query: 220  GAGPATQGG 228
             AGP  + G
Sbjct: 1549 VAGPKGEKG 1557



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 72/252 (28%), Positives = 85/252 (33%), Gaps = 62/252 (24%)

Query: 45   LPGPERR-GPR--------PPQTIPTLFLA--GVFSETEAPGSSTHVGA--GNSSDPATS 91
            LP PERR GP+        P +  P  F    G+  +   PG     G   G    P  S
Sbjct: 1971 LPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPS 2030

Query: 92   RLGGSRGPHPTLP--PGPAGSLVFPERRGSLQDR--------LGRASRPGCP-----PSP 136
             L G  G  P +P  PG AG +    R G   +R         GR   PG P     P P
Sbjct: 2031 GLAGEPGK-PGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGP 2089

Query: 137  RGSRQERGANSPGRSGARGCGGAAALQ--------QEPTNFRGRP-------RPGARGTD 181
             G +       PG SG +G  G    +        Q P   RG P        PG RG D
Sbjct: 2090 PGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQD 2149

Query: 182  -----PPGRTLPAPLARPSTQPGR-------------RPGLGRAASPLGPRGAGVTGAGP 223
                 P  R +  P  +P  Q  R              PG    A P GP+G       P
Sbjct: 2150 GNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEP 2209

Query: 224  ATQGGRDRGRWG 235
               G   RG  G
Sbjct: 2210 GETGPPGRGLTG 2221



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 57/203 (28%), Positives = 74/203 (36%), Gaps = 32/203 (15%)

Query: 36   LGSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGG 95
            +G   D  P   P   GP  PQ        G       PG +   G G +       L G
Sbjct: 2179 VGGHGDPGPPGAPGLAGPAGPQ--------GPSGLKGEPGETGPPGRGLTGPTGAVGLPG 2230

Query: 96   SRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERGANSPGRSGARG 155
                    PPGP+G LV P+    L  ++G   +PG P     S ++    SPG  G+ G
Sbjct: 2231 --------PPGPSG-LVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPG 2281

Query: 156  CGGAAALQQE--PTNFRGRP---RPGARG-TDPPGRTLPAPLARPSTQ--------PGRR 201
              G    + E  PT   G+     PGA+G    PG      +  P  +         G +
Sbjct: 2282 LPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEK 2341

Query: 202  PGLGRAASPLGPRGAGVTGA-GP 223
               GRA  P  P   G  GA GP
Sbjct: 2342 GEAGRAGEPGDPGEDGQKGAPGP 2364



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 82/273 (30%), Positives = 93/273 (34%), Gaps = 78/273 (28%)

Query: 36   LGSPLDRNPLPGPER-RGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRL 93
            L  P     LPGP    G   PQ  P L   G   ET  PG+    GA G   D  +  +
Sbjct: 2219 LTGPTGAVGLPGPPGPSGLVGPQGSPGL--PGQVGETGKPGAPGRDGASGKDGDRGSPGV 2276

Query: 94   GGSRG----------PHPTLPPGPA------------------GSLV----------FPE 115
             GS G          P PT  PG A                  G LV           P 
Sbjct: 2277 PGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPG 2336

Query: 116  RRGSLQDRLGRASRPGCP--------PSPRGSRQERGA---NSPGRSGARGCGGAAAL-- 162
             RG  +   GRA  PG P        P P+G + + G     SPG  G  G  G   L  
Sbjct: 2337 PRGE-KGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPG 2395

Query: 163  ------------QQEPTNFRGRPRP-GARG-TDPPGRT-LPAPLARPSTQPGR--RPGLG 205
                        Q  P    G+P P G RG   PPGR  +P PL  P   PG    PG  
Sbjct: 2396 LPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPG-PPGSVGPPGAS 2454

Query: 206  RAASPLGPRGAGVTGAGPATQGGRD--RGRWGR 236
                  G  G G+   GP  + G    RG  GR
Sbjct: 2455 GLKGDKGDPGVGL--PGPRGERGEPGIRGEDGR 2485



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 69/234 (29%), Positives = 81/234 (34%), Gaps = 41/234 (17%)

Query: 46   PGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPH---- 100
            PGP    P PP     L L G+       G     G  G    P  S   G  GP     
Sbjct: 2379 PGP----PGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREG 2434

Query: 101  ---PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCP-PSPRGSRQERGANS----PGRSG 152
               P  PPGP GS+  P   G   D+      PG   P PRG R E G       PG+ G
Sbjct: 2435 IPGPLGPPGPPGSVGPPGASGLKGDK----GDPGVGLPGPRGERGEPGIRGEDGRPGQEG 2490

Query: 153  ARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRRPGLGRAASPLG 212
             RG  G    + E          G +G       +  P           PG   A   +G
Sbjct: 2491 PRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGP-----------PGPRGAKGDMG 2539

Query: 213  PRG-AGVTG-AGPATQGG--RDRGRWGRWVRRRVPCPLPGLR----PHERAGAA 258
             RG  G+ G  GP    G   D+G  G     +    LPGLR    P  + GAA
Sbjct: 2540 ERGPRGLDGDKGPRGDNGDPGDKGSKGE-PGDKGSAGLPGLRGLLGPQGQPGAA 2592



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 68/234 (29%), Positives = 82/234 (35%), Gaps = 48/234 (20%)

Query: 5    GPRGSPETFVACAKSAQFGRGVIFVRSLFLILGSPLDRNPLPGPERRGPRPPQTIPTLF- 63
            GP+G P         A   RG+   R      G P  R P      RGP      P L  
Sbjct: 1731 GPKGDPGL-----PGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGP------PGLDG 1779

Query: 64   LAGVFSETEAPGSSTHVGA-GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQD 122
             +G+  +  A G S   GA G + DP    L G RG      PGP+G    P + G    
Sbjct: 1780 RSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGL--PGPSGPPGLPGKPGE-DG 1836

Query: 123  RLGRASRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDP 182
            + G   + G P  P            GR G +G  GA+               G  G D 
Sbjct: 1837 KPGLNGKNGEPGDP---------GEDGRKGEKGDSGAS---------------GREGRDG 1872

Query: 183  PGRTLPAP-LARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWG 235
            P     AP +  P   PG  PG      P+GP G G  G    T    DRG  G
Sbjct: 1873 PKGERGAPGILGPQGPPGL-PG------PVGPPGQGFPGVPGGTGPKGDRGETG 1919



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 54/179 (30%), Positives = 61/179 (34%), Gaps = 29/179 (16%)

Query: 83   GNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQE 142
            G   +P    L G  GP     PG  G    P R G        A  P  PP    ++ E
Sbjct: 1254 GQKGEPGEMGLRGQVGP-----PGDPG---LPGRTG--------APGPQGPPGSATAKGE 1297

Query: 143  RG-------ANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAP----L 191
            RG         SPGR+G  G  GA  L+  P     R  PG RG   P     AP     
Sbjct: 1298 RGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIG 1357

Query: 192  ARPSTQPGRR--PGLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGRWVRRRVPCPLPG 248
                  PGR+  PG      P GP G       P   G   +G  G    R  P P  G
Sbjct: 1358 GEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEG 1416



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 43/144 (29%), Positives = 53/144 (36%), Gaps = 19/144 (13%)

Query: 74   PGSSTHVGAGNSSDPATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDR--LGRASRPG 131
            PG + H   G   +P      G+ G    +  GP G   F  + G   D+   G    PG
Sbjct: 2652 PGLAGH--KGEMGEPGVPGQSGAPGKEGLI--GPKGDRGFDGQPGPKGDQGEKGERGTPG 2707

Query: 132  CPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPL 191
                P  S  +  A  PG  G+ G  G   LQ +          G RG  PPG  +    
Sbjct: 2708 IGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQ---------KGERG--PPGERVVGAP 2756

Query: 192  ARPSTQPGRRPGLGRAASPLGPRG 215
              P   PG R   GR   P GPRG
Sbjct: 2757 GVPGA-PGERGEQGR-PGPAGPRG 2778



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 33/92 (35%), Positives = 40/92 (43%), Gaps = 10/92 (10%)

Query: 83   GNSSDPATSRLGGSRGPH----PTLPPGPAGSLVFPERRGSLQDRLGRASRPG----CPP 134
            G   +  T  +GG  GP        PPGP GS V P     LQ + G    PG      P
Sbjct: 2698 GEKGERGTPGIGGFPGPSGNDGSAGPPGPPGS-VGPRGPEGLQGQKGERGPPGERVVGAP 2756

Query: 135  SPRGSRQERGANS-PGRSGARGCGGAAALQQE 165
               G+  ERG    PG +G RG  G AAL ++
Sbjct: 2757 GVPGAPGERGEQGRPGPAGPRGEKGEAALTED 2788



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 65/220 (29%), Positives = 78/220 (35%), Gaps = 35/220 (15%)

Query: 37   GSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGA-GNSSDPATSRLGG 95
            G P D+     P  RG   PQ  P    AG+  +  +PG     G  G   D       G
Sbjct: 2566 GEPGDKGSAGLPGLRGLLGPQGQPGA--AGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRG 2623

Query: 96   SRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGCP--PSPRGSRQERGANSPGRSGA 153
             +G       G  G+      +G      G A  PG P     +G   E G   PG+SGA
Sbjct: 2624 LKGER-----GVKGACGLDGEKGDK----GEAGPPGRPGLAGHKGEMGEPGV--PGQSGA 2672

Query: 154  RGCGGAAALQQEPTNFRGRPRP-------GARGTDPPGRTLPAPL-----ARPSTQPG-- 199
             G  G    + +   F G+P P       G RGT   G   P P      A P   PG  
Sbjct: 2673 PGKEGLIGPKGD-RGFDGQPGPKGDQGEKGERGTPGIGG-FPGPSGNDGSAGPPGPPGSV 2730

Query: 200  --RRP-GLGRAASPLGPRGAGVTGAGPATQGGRDRGRWGR 236
              R P GL       GP G  V GA        +RG  GR
Sbjct: 2731 GPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGR 2770



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 30/94 (31%), Positives = 35/94 (37%), Gaps = 17/94 (18%)

Query: 40   LDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGSRGP 99
            L   PL GP +  P  PQT+P     G+ S     G    V    S  P    L G RGP
Sbjct: 987  LSWRPLRGPGQEVPGSPQTLP-----GISSSQRVTGLEPGVSYIFSLTPV---LDGVRGP 1038

Query: 100  H------PTLPPGPAGSLVFPERRGSLQDRLGRA 127
                   P  P G A  +  P    + QD   RA
Sbjct: 1039 EASVTQTPVCPRGLADVVFLPH---ATQDNAHRA 1069


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 63/227 (27%), Positives = 76/227 (33%), Gaps = 72/227 (31%)

Query: 36  LGSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDP------- 88
           +G P    P+    R GP  P+            E   PGS      G + +P       
Sbjct: 611 VGDPGMEGPMGQRGREGPMGPR-----------GEAGPPGSGEKGERGAAGEPGPHGPPG 659

Query: 89  ---ATSRLGGSRGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGC--------PPSPR 137
              +    G S  P P  PPGP G          LQ   G    PG         PP P+
Sbjct: 660 VPGSVGPKGSSGSPGPQGPPGPVG----------LQGLRGEVGLPGVKGDKGPMGPPGPK 709

Query: 138 GSRQERG----------------ANSPGRSGARGCGGAAALQQEPTNFRGRP-RPGARGT 180
           G + E+G                   PG  GA G  G     Q P   +G    PG RG 
Sbjct: 710 GDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDG-HQGPRGEQGLTGMPGIRG- 767

Query: 181 DPPGRTLPAPLARPSTQPGRRPGLGRAASPLGPRGAGVTGAGPATQG 227
            PPG         PS  PG+ PGL     P GP+G   T   P  +G
Sbjct: 768 -PPG---------PSGDPGK-PGL---TGPQGPQGLPGTPGRPGIKG 800



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 65/194 (33%), Positives = 75/194 (38%), Gaps = 38/194 (19%)

Query: 35  ILGSPLDRNPLPGPER-------RGPRPPQTIP-TLFLAGVFSETEAPGSS-THVGAGNS 85
           + G P  R P PGP          GP+ PQ +P T    G+  E  APG   T  G+   
Sbjct: 759 LTGMPGIRGP-PGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSML 817

Query: 86  SDPATSRLGGSRGPH-PTLPPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERG 144
           + P      G+ GP  P   PGPAG    P      Q+ L     PG PP PRG     G
Sbjct: 818 TVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGH----QEVLNLQGPPG-PPGPRGPP---G 869

Query: 145 ANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAP---LARPSTQPGRR 201
            + PG  G RG  G            G P P      PPG  L      L+ P   PG  
Sbjct: 870 PSIPGPPGPRGPPG-----------EGLPGP----PGPPGSFLSNSETFLSGPPGPPG-P 913

Query: 202 PGLGRAASPLGPRG 215
           PG      P GPRG
Sbjct: 914 PGPKGDQGPPGPRG 927



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 41/149 (27%), Positives = 54/149 (36%), Gaps = 15/149 (10%)

Query: 73  APGSSTHVGA----GNSSDPATSRLGGSRG-PHPTLPPGPAGSLVFPERRGSLQDRLGRA 127
           +PG    +G+    G+   P T  + G  G P P  P G  GS+  P   G +    G+ 
Sbjct: 568 SPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPM----GQR 623

Query: 128 SRPGCPPSPRGSRQERGANSPGRSGARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTL 187
            R G    P G R E G    G  G RG  G       P    G   P      P  +  
Sbjct: 624 GREG----PMGPRGEAGPPGSGEKGERGAAGEPG-PHGPPGVPGSVGPKGSSGSPGPQGP 678

Query: 188 PAPLARPSTQ-PGRRPGLGRAASPLGPRG 215
           P P+     +     PG+     P+GP G
Sbjct: 679 PGPVGLQGLRGEVGLPGVKGDKGPMGPPG 707



 Score = 35.8 bits (81), Expect = 0.054
 Identities = 52/185 (28%), Positives = 60/185 (32%), Gaps = 15/185 (8%)

Query: 37  GSPLDRNPLPGPERRGPRPPQTIPTLFLAGVFSETEAPGSSTHVGAGNSSDPATSRLGGS 96
           G P    P   P   GP  P  +P      V +    PG     G    S P      G 
Sbjct: 824 GPPGAMGPPGPPGAPGPAGPAGLPGH--QEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGP 881

Query: 97  RGPHPTLPPGPAGSLVFPERRGSLQDRLGRASRPGC-----PPSPRGSRQERGANSPGRS 151
            G     PPGP GS +       L    G    PG      PP PRG + E+G   PG S
Sbjct: 882 PGEGLPGPPGPPGSFL-SNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGL--PGFS 938

Query: 152 GARGCGGAAALQQEPTNFRGRPRPGARGTDPPGRTLPAPLARPS-TQPGRRPGLGRAASP 210
            +        LQ  P    G P P     D     +P  L  PS    G        + P
Sbjct: 939 TSGSSSFGLNLQGPP----GPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGP 994

Query: 211 LGPRG 215
            GP G
Sbjct: 995 PGPPG 999



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%)

Query: 104  PPGPAGSLVFPERRGSLQDRLGRASRPGCPPSPRGSRQERG 144
            PPG  G +  P  +G  +   G    PG PP PRG + E+G
Sbjct: 1439 PPGQKGEMGTPGPKGD-RGPAGPPGHPG-PPGPRGHKGEKG 1477


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.138    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,636,099
Number of Sequences: 37866
Number of extensions: 1407021
Number of successful extensions: 11333
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 147
Number of HSP's successfully gapped in prelim test: 1332
Number of HSP's that attempted gapping in prelim test: 7560
Number of HSP's gapped (non-prelim): 3728
length of query: 330
length of database: 18,247,518
effective HSP length: 103
effective length of query: 227
effective length of database: 14,347,320
effective search space: 3256841640
effective search space used: 3256841640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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