Search of human proteins with 111118978

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
         (986 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap...  2003   0.0  
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...  1998   0.0  
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]            1515   0.0  
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]           1412   0.0  
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap...  1175   0.0  
gi|4758280 ephrin receptor EphA4 [Homo sapiens]                      1168   0.0  
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap...  1164   0.0  
gi|4758282 ephrin receptor EphA7 [Homo sapiens]                      1162   0.0  
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi...  1126   0.0  
gi|32528301 EPH receptor B4 precursor [Homo sapiens]                 1092   0.0  
gi|145312251 EPH receptor A6 isoform a [Homo sapiens]                1078   0.0  
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi...  1033   0.0  
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]           935   0.0  
gi|32967311 ephrin receptor EphA2 [Homo sapiens]                      905   0.0  
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]                 810   0.0  
gi|221316650 ephrin receptor EphA1 [Homo sapiens]                     722   0.0  
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi...   569   e-162
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi...   441   e-123
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]                267   4e-71
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]     228   3e-59
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]              226   6e-59
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]   223   9e-58
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]   223   9e-58
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...   222   1e-57
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...   222   1e-57
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]       221   2e-57
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs...   221   3e-57
gi|112789546 lymphocyte-specific protein tyrosine kinase precurs...   221   3e-57
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap...   220   4e-57
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi...   220   4e-57

>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
           sapiens]
          Length = 986

 Score = 2003 bits (5188), Expect = 0.0
 Identities = 986/986 (100%), Positives = 986/986 (100%)

Query: 1   MALRRLGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQ 60
           MALRRLGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQ
Sbjct: 1   MALRRLGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQ 60

Query: 61  VCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADF 120
           VCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADF
Sbjct: 61  VCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADF 120

Query: 121 DSATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQD 180
           DSATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQD
Sbjct: 121 DSATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQD 180

Query: 181 YGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLY 240
           YGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLY
Sbjct: 181 YGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLY 240

Query: 241 CNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGA 300
           CNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGA
Sbjct: 241 CNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGA 300

Query: 301 TNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNI 360
           TNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNI
Sbjct: 301 TNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNI 360

Query: 361 ICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPF 420
           ICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPF
Sbjct: 361 ICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPF 420

Query: 421 SPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSE 480
           SPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSE
Sbjct: 421 SPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSE 480

Query: 481 YNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEK 540
           YNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEK
Sbjct: 481 YNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEK 540

Query: 541 LPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPF 600
           LPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPF
Sbjct: 541 LPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPF 600

Query: 601 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 660
           TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT
Sbjct: 601 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 660

Query: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 720
           EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV
Sbjct: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 720

Query: 721 IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY 780
           IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY
Sbjct: 721 IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY 780

Query: 781 TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE 840
           TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE
Sbjct: 781 TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE 840

Query: 841 QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI 900
           QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI
Sbjct: 841 QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI 900

Query: 901 NLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTL 960
           NLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTL
Sbjct: 901 NLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTL 960

Query: 961 AGHQKKILNSIQVMRAQMNQIQSVEV 986
           AGHQKKILNSIQVMRAQMNQIQSVEV
Sbjct: 961 AGHQKKILNSIQVMRAQMNQIQSVEV 986


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
           sapiens]
          Length = 987

 Score = 1998 bits (5176), Expect = 0.0
 Identities = 986/987 (99%), Positives = 986/987 (99%), Gaps = 1/987 (0%)

Query: 1   MALRRLGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQ 60
           MALRRLGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQ
Sbjct: 1   MALRRLGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQ 60

Query: 61  VCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADF 120
           VCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADF
Sbjct: 61  VCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADF 120

Query: 121 DSATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQD 180
           DSATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQD
Sbjct: 121 DSATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQD 180

Query: 181 YGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLY 240
           YGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLY
Sbjct: 181 YGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLY 240

Query: 241 CNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGA 300
           CNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGA
Sbjct: 241 CNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGA 300

Query: 301 TNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNI 360
           TNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNI
Sbjct: 301 TNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNI 360

Query: 361 ICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPF 420
           ICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPF
Sbjct: 361 ICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPF 420

Query: 421 SPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSE 480
           SPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSE
Sbjct: 421 SPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSE 480

Query: 481 YNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEK 540
           YNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEK
Sbjct: 481 YNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEK 540

Query: 541 LPLIIGSSAAGLVFLIAVVVIAIVCN-RRGFERADSEYTDKLQHYTSGHMTPGMKIYIDP 599
           LPLIIGSSAAGLVFLIAVVVIAIVCN RRGFERADSEYTDKLQHYTSGHMTPGMKIYIDP
Sbjct: 541 LPLIIGSSAAGLVFLIAVVVIAIVCNRRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDP 600

Query: 600 FTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGY 659
           FTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGY
Sbjct: 601 FTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGY 660

Query: 660 TEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT 719
           TEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT
Sbjct: 661 TEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT 720

Query: 720 VIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT 779
           VIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT
Sbjct: 721 VIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT 780

Query: 780 YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAI 839
           YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAI
Sbjct: 781 YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAI 840

Query: 840 EQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSG 899
           EQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSG
Sbjct: 841 EQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSG 900

Query: 900 INLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVT 959
           INLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVT
Sbjct: 901 INLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVT 960

Query: 960 LAGHQKKILNSIQVMRAQMNQIQSVEV 986
           LAGHQKKILNSIQVMRAQMNQIQSVEV
Sbjct: 961 LAGHQKKILNSIQVMRAQMNQIQSVEV 987


>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
          Length = 984

 Score = 1515 bits (3923), Expect = 0.0
 Identities = 716/971 (73%), Positives = 846/971 (87%), Gaps = 1/971 (0%)

Query: 10  LLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQ 69
           LLL   +AA+EETLMD+ TATAELGW  +P SGWEEVSGYDEN+NTIRTYQVCNVFE +Q
Sbjct: 9   LLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQ 68

Query: 70  NNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPN 129
           NNWL T FI RRGAHRI+ EM+F+VRDCSS+P+VPGSCKETFNLYYYE D   ATK    
Sbjct: 69  NNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAF 128

Query: 130 WMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIA 189
           W E P++KVDTIAADESFSQVD GGR+MK+NTEVRSFGP++R+GFYLAFQDYG CMSL++
Sbjct: 129 WSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLS 188

Query: 190 VRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLV 249
           VRVF++KCP I+QN A+F ET++GAESTSLV ARG+CI NAEEVDVPIKLYCNGDGEW+V
Sbjct: 189 VRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMV 248

Query: 250 PIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGY 309
           PIGRC CK G+E  EN   C+ CP+GTFKA+Q  E C+HCP NSR+ +E +  C CR GY
Sbjct: 249 PIGRCTCKPGYEP-ENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGY 307

Query: 310 YRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGR 369
           YRAD DP ++ CT++PS P+ VIS VNETS++LEW PPR++GGR+D+ YNIICK C + R
Sbjct: 308 YRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADR 367

Query: 370 GACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNI 429
            +C+RC DNV++ PRQLGLTE R+ IS L AHT YTF+IQA+NGV+ +SPF PQ  SVNI
Sbjct: 368 RSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNI 427

Query: 430 TTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSP 489
           TTNQAAPS V IMHQVS T+ SITLSW QP+QPNG+ILDYE++YYEKE +E+N++  +S 
Sbjct: 428 TTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQ 487

Query: 490 TNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSA 549
           TNT  + GL+ G +YV QVRARTVAGYG++SGKM FQT+T+ +Y++ ++E+LPLI GS+A
Sbjct: 488 TNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAA 547

Query: 550 AGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAV 609
           AG+VF++++V I+IVC+R+     ++ Y+DKLQHY++G  +PGMKIYIDPFTYEDPNEAV
Sbjct: 548 AGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAV 607

Query: 610 REFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLS 669
           REFAKEID+S VKIE+VIGAGEFGEV  G LKLPGKREI+VAIKTLK+GY+EKQRRDFLS
Sbjct: 608 REFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLS 667

Query: 670 EASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRG 729
           EASIMGQFDHPN+I LEGVVTKS PVMIITEFMENG+LDSFLRQNDGQFTVIQLVGMLRG
Sbjct: 668 EASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRG 727

Query: 730 IAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIP 789
           IAAGMKYLA+MNYVHRDLAARNILVNSNLVCKVSDFGLSR+L+DDTSDPTYTS+LGGKIP
Sbjct: 728 IAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIP 787

Query: 790 IRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPM 849
           +RWTAPEAI YRKFTSASDVWSYGIVMWEVMS+GERPYWDM+NQDVINAIEQDYRLPPPM
Sbjct: 788 VRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPM 847

Query: 850 DCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTI 909
           DCP+ALHQLMLDCWQKDRN RP+F +IVNTLDKMIRNP SLK +A +++  + PLLDR+I
Sbjct: 848 DCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSI 907

Query: 910 PDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILN 969
           PD+T+F TVD+WL AIKM QY++SF  AGFTS  +V+QM  ED+LR+G+TLAGHQKKILN
Sbjct: 908 PDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILN 967

Query: 970 SIQVMRAQMNQ 980
           SI  MR Q++Q
Sbjct: 968 SIHSMRVQISQ 978


>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
          Length = 998

 Score = 1412 bits (3656), Expect = 0.0
 Identities = 694/986 (70%), Positives = 809/986 (82%), Gaps = 19/986 (1%)

Query: 10  LLLLPLLA------AVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCN 63
           LLLLPLL       A+EETLMD+   T+EL W  HP SGWEEVSGYDE MN IRTYQVCN
Sbjct: 23  LLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCN 82

Query: 64  VFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSA 123
           V ESSQNNWLRT FI RR   R++VE+KF+VRDC+SIP++PGSCKETFNL+YYEAD D A
Sbjct: 83  VRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVA 142

Query: 124 TKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGG 183
           + + P WMENP+VKVDTIA DESFS++D G    ++NT+VRSFGP+S++GFYLAFQD G 
Sbjct: 143 SASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGA 198

Query: 184 CMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNG 243
           CMSLI+VR FY+KC       A+F ETL+GAE TSLV A G+CI NA EV VP+KLYCNG
Sbjct: 199 CMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNG 258

Query: 244 DGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNC 303
           DGEW+VP+G C C  G E     + CR CP G++KA QG+  C  CP NSRTTS  A+ C
Sbjct: 259 DGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASIC 318

Query: 304 VCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICK 363
            C N +YRAD D  D  CTT+PS P+ VIS+VNETSL+LEW+ PRD GGR+DL+YN+ICK
Sbjct: 319 TCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICK 378

Query: 364 SC--GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFS 421
            C    G  AC+RC DNV++ PRQLGLTE R++IS LLAHT+YTFE+QAVNGV+ +SP  
Sbjct: 379 KCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLP 438

Query: 422 PQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEY 481
           P++A+VNITTNQAAPS V  +   S +  S+TLSW+ P++PNGVILDYE++Y+EK  SE 
Sbjct: 439 PRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEK--SEG 496

Query: 482 NATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTE-AEYQTSIQEK 540
            A+ + S  N+V + GL+  A YV QVRARTVAGYG+YS    F+T +E       +QE+
Sbjct: 497 IASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQ 556

Query: 541 LPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPF 600
           LPLI+GS+ AGLVF++AVVVIAIVC R+    +DSEYT+KLQ Y    + PGMK+YIDPF
Sbjct: 557 LPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY----IAPGMKVYIDPF 612

Query: 601 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 660
           TYEDPNEAVREFAKEID+SCVKIE+VIGAGEFGEVC G LK PG+RE+FVAIKTLK GYT
Sbjct: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYT 672

Query: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 720
           E+QRRDFLSEASIMGQFDHPN+I LEGVVTKS PVMI+TEFMEN +LDSFLR NDGQFTV
Sbjct: 673 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTV 732

Query: 721 IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY 780
           IQLVGMLRGIAAGMKYL++MNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDD SDPTY
Sbjct: 733 IQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTY 792

Query: 781 TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE 840
           TS+LGGKIPIRWTAPEAI YRKFTSASDVWSYGIVMWEVMSYGERPYWDM+NQDVINA+E
Sbjct: 793 TSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVE 852

Query: 841 QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI 900
           QDYRLPPPMDCP+ALHQLMLDCW +DRN RPKF QIVNTLDK+IRN  SLK +A   SG+
Sbjct: 853 QDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGM 912

Query: 901 NLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTL 960
           + PLLDRT+PDYT+F TV +WL+AIKMG+YKESF +AGF SFD+V+QM  ED+LR+GVTL
Sbjct: 913 SQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTL 972

Query: 961 AGHQKKILNSIQVMRAQMNQIQSVEV 986
           AGHQKKIL+SIQ MR QMNQ   V+V
Sbjct: 973 AGHQKKILSSIQDMRLQMNQTLPVQV 998


>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
          Length = 1015

 Score = 1175 bits (3040), Expect = 0.0
 Identities = 573/974 (58%), Positives = 738/974 (75%), Gaps = 12/974 (1%)

Query: 6    LGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVF 65
            L AAL  L    + E  L+DS T   +LGW+  P +GWEE+   DEN   I TYQVC V 
Sbjct: 46   LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVM 105

Query: 66   ESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125
            E +QNNWL T +I   GA RI +E+KF++RDC+S+P   G+CKETFN+YY+E+D  +   
Sbjct: 106  EQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGR- 164

Query: 126  TFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCM 185
               N  EN ++K+DTIAADESF+++DLG RVMK+NTEVR  GP+S+ GFYLAFQD G C+
Sbjct: 165  ---NIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACI 221

Query: 186  SLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDG 245
            +L++VRV+Y+KCP ++++ A+F +T++GA+S+ L+   GSC+ N    D P K++C+ +G
Sbjct: 222  ALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSAEG 280

Query: 246  EWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVC 305
            EWLVPIG+CMCKAG+E  +NGT C+ C  G FKA+   ++C  CP +S T  E +T+CVC
Sbjct: 281  EWLVPIGKCMCKAGYEE-KNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVC 338

Query: 306  RNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSC 365
               Y+R + DP  M CT  PSAP+  IS+VNETS+ LEW PP D+GGR+D+ Y I CK C
Sbjct: 339  EKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKC 398

Query: 366  GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFA 425
             S  G C  CG +V+Y PRQ GL    + + DLLAHT YTFEI+AVNGV+D SP + Q+ 
Sbjct: 399  NSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYV 458

Query: 426  SVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA 485
            SVN+TTNQAAPS V+ + +     +SI+LSW +PD+PNG+IL+YE++Y+EK+  E + T 
Sbjct: 459  SVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD-QETSYTI 517

Query: 486  IKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLII 545
            IKS   T+T +GLK  ++YVFQ+RART AGYG +S +  F+T T     +S Q ++P+I 
Sbjct: 518  IKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIA 576

Query: 546  GSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMT-PGMKIYIDPFTYED 604
             S   G++ L  V+ + +   R G+ +A  +  ++  H+ +GH+  PG++ YIDP TYED
Sbjct: 577  VSVTVGVILLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYED 636

Query: 605  PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQR 664
            PN+AV EFAKEI+ SC+ IE+VIGAGEFGEVCSG LKLPGKRE+ VAIKTLK GYTEKQR
Sbjct: 637  PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQR 696

Query: 665  RDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLV 724
            RDFL EASIMGQFDHPN+IHLEGVVTKS PVMI+TE+MENGSLD+FL++NDGQFTVIQLV
Sbjct: 697  RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLV 756

Query: 725  GMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSAL 784
            GMLRGI+AGMKYL+DM YVHRDLAARNIL+NSNLVCKVSDFGLSR LEDD  +  YT+  
Sbjct: 757  GMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTTR- 814

Query: 785  GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 844
            GGKIPIRWTAPEAI +RKFTSASDVWSYGIVMWEV+SYGERPYW+MTNQDVI A+E+ YR
Sbjct: 815  GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 874

Query: 845  LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPL 904
            LP PMDCP+AL+QLMLDCWQK+RN RPKF +IVN LDK+IRNP+SLK +   S  ++  L
Sbjct: 875  LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLL 934

Query: 905  LDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQ 964
             + +     ++ +V EWLEAIKMG+Y E F   G++S D V+Q+ +ED+ R+GVTL GHQ
Sbjct: 935  AEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQ 994

Query: 965  KKILNSIQVMRAQM 978
            KKI+NS+Q M+ Q+
Sbjct: 995  KKIMNSLQEMKVQL 1008


>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
          Length = 986

 Score = 1168 bits (3021), Expect = 0.0
 Identities = 577/967 (59%), Positives = 724/967 (74%), Gaps = 18/967 (1%)

Query: 18  AVEETLMDSTTATAELGWMVHP-PSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTK 76
           A E TL+DS +   ELGW+  P   GWEEVS  DE    IRTYQVCNV E SQNNWLRT 
Sbjct: 28  ANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTD 87

Query: 77  FIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWV 136
           +I R GA R+++E+KF++RDC+S+P V G+CKETFNLYYYE+D D          EN +V
Sbjct: 88  WITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFI----RENQFV 143

Query: 137 KVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRK 196
           K+DTIAADESF+QVD+G R+MK+NTE+R  GP+S+ GFYLAFQD G C++L++VRVFY+K
Sbjct: 144 KIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 203

Query: 197 CPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMC 256
           CP  ++N A F +T++GA+++SLV  RGSC+ N+EE DVP K+YC  DGEWLVPIG C+C
Sbjct: 204 CPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVP-KMYCGADGEWLVPIGNCLC 262

Query: 257 KAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDP 316
            AG E  E    C+ C  G +KA   D  C  CP +S +  EGAT+C C  G++RAD D 
Sbjct: 263 NAGHE--ERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDA 320

Query: 317 LDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGA-CTRC 375
             MPCT  PSAP  +IS+VNETS+ LEW+ P+++GGR+D+ YN++CK CG+G  + C  C
Sbjct: 321 ASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPC 380

Query: 376 GDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAA 435
           G  V Y P+Q GL   ++ I+DLLAHT YTFEI AVNGV+  +P   Q  SV +TTNQAA
Sbjct: 381 GSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAA 440

Query: 436 PSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTV 495
           PS+++++     T  S+ L+W +PD+PNGVIL+YE++YYEK+ +E +   +++      +
Sbjct: 441 PSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDI 500

Query: 496 QGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFL 555
           +GL     YVF VRART AGYG +S  +   T T             +++  S +G V L
Sbjct: 501 KGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLL-VSVSGSVVL 559

Query: 556 IAVVVIAIVCNRRGFERADSEYTDKLQHYTSG-HMTPGMKIYIDPFTYEDPNEAVREFAK 614
           + +++ A V +RR      S+Y+   Q      H+  G++ Y+DPFTYEDPN+AVREFAK
Sbjct: 560 VVILIAAFVISRRR-----SKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAK 614

Query: 615 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 674
           EID SC+KIE+VIG GEFGEVCSG LK+PGKREI VAIKTLK+GYT+KQRRDFLSEASIM
Sbjct: 615 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIM 674

Query: 675 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
           GQFDHPN+IHLEGVVTK  PVMIITE+MENGSLD+FLR+NDG+FTVIQLVGMLRGI +GM
Sbjct: 675 GQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGM 734

Query: 735 KYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTA 794
           KYL+DM+YVHRDLAARNILVNSNLVCKVSDFG+SR LEDD  +  YT+  GGKIPIRWTA
Sbjct: 735 KYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDD-PEAAYTTR-GGKIPIRWTA 792

Query: 795 PEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSA 854
           PEAI YRKFTSASDVWSYGIVMWEVMSYGERPYWDM+NQDVI AIE+ YRLPPPMDCP A
Sbjct: 793 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIA 852

Query: 855 LHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTS 914
           LHQLMLDCWQK+R+ RPKFGQIVN LDK+IRNPNSLK     SS  N  LLD + P++++
Sbjct: 853 LHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSA 912

Query: 915 FNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVM 974
             +V +WL+AIKM +YK++F  AG+T+ + V  +  ED+ R+G+T   HQ KIL+S+Q M
Sbjct: 913 VVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAM 972

Query: 975 RAQMNQI 981
           R QM Q+
Sbjct: 973 RTQMQQM 979


>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
          Length = 1037

 Score = 1164 bits (3010), Expect = 0.0
 Identities = 574/996 (57%), Positives = 739/996 (74%), Gaps = 34/996 (3%)

Query: 6    LGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVF 65
            L AAL  L    + E  L+DS T   +LGW+  P +GWEE+   DEN   I TYQVC V 
Sbjct: 46   LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVM 105

Query: 66   ESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125
            E +QNNWL T +I   GA RI +E+KF++RDC+S+P   G+CKETFN+YY+E+D  +   
Sbjct: 106  EQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGR- 164

Query: 126  TFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCM 185
               N  EN ++K+DTIAADESF+++DLG RVMK+NTEVR  GP+S+ GFYLAFQD G C+
Sbjct: 165  ---NIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACI 221

Query: 186  SLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDG 245
            +L++VRV+Y+KCP ++++ A+F +T++GA+S+ L+   GSC+ N    D P K++C+ +G
Sbjct: 222  ALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSAEG 280

Query: 246  EWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVC 305
            EWLVPIG+CMCKAG+E  +NGT C+ C  G FKA+   ++C  CP +S T  E +T+CVC
Sbjct: 281  EWLVPIGKCMCKAGYEE-KNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVC 338

Query: 306  RNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSC 365
               Y+R + DP  M CT  PSAP+  IS+VNETS+ LEW PP D+GGR+D+ Y I CK C
Sbjct: 339  EKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKC 398

Query: 366  GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFA 425
             S  G C  CG +V+Y PRQ GL    + + DLLAHT YTFEI+AVNGV+D SP + Q+ 
Sbjct: 399  NSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYV 458

Query: 426  SVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA 485
            SVN+TTNQAAPS V+ + +     +SI+LSW +PD+PNG+IL+YE++Y+EK+  E + T 
Sbjct: 459  SVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD-QETSYTI 517

Query: 486  IKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLII 545
            IKS   T+T +GLK  ++YVFQ+RART AGYG +S +  F+T T     +S Q ++P+I 
Sbjct: 518  IKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIA 576

Query: 546  GSSAAGLVFLIAVVVIAIV-------CNRR---------------GFERADSEYTDKLQH 583
             S   G++ L  V+ + +        C R                G+ +A  +  ++  H
Sbjct: 577  VSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMH 636

Query: 584  YTSGHMT-PGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKL 642
            + +GH+  PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE+VIGAGEFGEVCSG LKL
Sbjct: 637  FHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKL 696

Query: 643  PGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFM 702
            PGKRE+ VAIKTLK GYTEKQRRDFL EASIMGQFDHPN+IHLEGVVTKS PVMI+TE+M
Sbjct: 697  PGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYM 756

Query: 703  ENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKV 762
            ENGSLD+FL++NDGQFTVIQLVGMLRGI+AGMKYL+DM YVHRDLAARNIL+NSNLVCKV
Sbjct: 757  ENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKV 816

Query: 763  SDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY 822
            SDFGLSR LEDD  +  YT+  GGKIPIRWTAPEAI +RKFTSASDVWSYGIVMWEV+SY
Sbjct: 817  SDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY 874

Query: 823  GERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDK 882
            GERPYW+MTNQDVI A+E+ YRLP PMDCP+AL+QLMLDCWQK+RN RPKF +IVN LDK
Sbjct: 875  GERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDK 934

Query: 883  MIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSF 942
            +IRNP+SLK +   S  ++  L + +     ++ +V EWLEAIKMG+Y E F   G++S 
Sbjct: 935  LIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSM 994

Query: 943  DVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQM 978
            D V+Q+ +ED+ R+GVTL GHQKKI+NS+Q M+ Q+
Sbjct: 995  DAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030


>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
          Length = 998

 Score = 1162 bits (3006), Expect = 0.0
 Identities = 572/971 (58%), Positives = 727/971 (74%), Gaps = 20/971 (2%)

Query: 17  AAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTK 76
           AA E  L+DS     EL W+  PP+GWEE+SG DEN   IRTYQVC V E +QNNWLRT 
Sbjct: 29  AAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTN 88

Query: 77  FIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWV 136
           +I +  A RI VE+KF++RDC+S+P V G+CKETFNLYYYE D+D+      N  EN +V
Sbjct: 89  WISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGR----NIRENLYV 144

Query: 137 KVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRK 196
           K+DTIAADESF+Q DLG R MK+NTEVR  GP+S+ GFYLAFQD G C++L++V+V+Y+K
Sbjct: 145 KIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKK 204

Query: 197 CPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEE-VDVPIKLYCNGDGEWLVPIGRCM 255
           C  II+N AIF +T++G+E +SLV  RG+C+++AEE  +   +++C+ +GEWLVPIG+C+
Sbjct: 205 CWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCI 264

Query: 256 CKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLD 315
           CKAG++  + G  C  C  G +K++  D  C+ CP +S +  EG++ C C +GYYRA  D
Sbjct: 265 CKAGYQ--QKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSD 322

Query: 316 PLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRC 375
           P  + CT  PSAPQ +I ++N+T++ LEW+PP D+GGR D+ Y I+CK C   +G C  C
Sbjct: 323 PPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPC 382

Query: 376 GDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAA 435
           G N+ Y P+Q GL +  + + DLLAH  YTFE++AVNGV+D S     FA+V+ITT QAA
Sbjct: 383 GSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAA 442

Query: 436 PSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTV 495
           PS VS + +      S+ LSW +P+ PNGVI +YE++YYEK+  E   + +K+ + + ++
Sbjct: 443 PSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASI 502

Query: 496 QGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEA-----EYQTSIQEKLPLIIGS--S 548
             LK G +YVFQ+RA T AGYG YS ++   T+ EA     E      E+ P+II +  +
Sbjct: 503 NNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVA 562

Query: 549 AAGLVFLIAVVVIAIVCNRR-GFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNE 607
            AG + L+ +V   I+  R  G+ +AD E  ++L  +      PG K YIDP TYEDPN 
Sbjct: 563 VAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFK---FPGTKTYIDPETYEDPNR 619

Query: 608 AVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDF 667
           AV +FAKE+D SC+KIE+VIGAGEFGEVCSG LKLPGKR++ VAIKTLK GYTEKQRRDF
Sbjct: 620 AVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDF 679

Query: 668 LSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGML 727
           L EASIMGQFDHPNV+HLEGVVT+  PVMI+ EFMENG+LD+FLR++DGQFTVIQLVGML
Sbjct: 680 LCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGML 739

Query: 728 RGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGK 787
           RGIAAGM+YLADM YVHRDLAARNILVNSNLVCKVSDFGLSR +EDD  +  YT+  GGK
Sbjct: 740 RGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDD-PEAVYTTT-GGK 797

Query: 788 IPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPP 847
           IP+RWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM+NQDVI AIE+ YRLP 
Sbjct: 798 IPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPA 857

Query: 848 PMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDR 907
           PMDCP+ LHQLMLDCWQK+R  RPKF QIV  LDKMIRNPNSLK      S    PLLD+
Sbjct: 858 PMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQ 917

Query: 908 TIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKI 967
             PD+T+F +V EWL+AIKM +YK++F  AG+ S + V++M +ED++ +G+TL GHQKKI
Sbjct: 918 NTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKI 977

Query: 968 LNSIQVMRAQM 978
           ++SIQ MRAQM
Sbjct: 978 MSSIQTMRAQM 988


>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
           sapiens]
          Length = 983

 Score = 1126 bits (2913), Expect = 0.0
 Identities = 550/962 (57%), Positives = 719/962 (74%), Gaps = 19/962 (1%)

Query: 20  EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79
           E  L+DS T   ELGW+ +P  GWEE+SG DE+   IRTYQVCNV + SQNNWLRT ++ 
Sbjct: 29  EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88

Query: 80  RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139
           R  A +I+VE+KF++RDC+SIP V G+CKETFNLYY E+D D   K    + E+ + K+D
Sbjct: 89  RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144

Query: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199
           TIAADESF+Q+DLG R++K+NTE+R  GPV++ GFYLAFQD G C++L++VRV+++KCP 
Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204

Query: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259
            ++N A+F +T+   +S SLV  RGSC+ N++E D P ++YC+ +GEWLVPIG+C C AG
Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262

Query: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319
           +E  E G +C+ C  G +KA  G+  C  CP +S T  +G+ NC C N Y+RAD DP  M
Sbjct: 263 YE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320

Query: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379
            CT  PS+P+ VIS++NETS++L+W+ P D+GGR+D+ +NIICK CG     C  C  NV
Sbjct: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNV 380

Query: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAV 439
           ++ PRQ GLT   + ++DLLAHT YTFEI AVNGV++ S    QFA+V+ITTNQAAPS V
Sbjct: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV 440

Query: 440 SIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLK 499
             + +   + +SI+LSW +P+ PNG+ILDYE++YYEK+  E + T +++    VT+  LK
Sbjct: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500

Query: 500 AGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVV 559
              IYVFQ+RART AGYG  S K  F+T  ++ +  S +    ++I  SAA  + L+ VV
Sbjct: 501 PDTIYVFQIRARTAAGYGTNSRKFEFETSPDS-FSISGESSQVVMIAISAAVAIILLTVV 559

Query: 560 VIAIV---CNRRGFERADSEYTDKLQHYTSGHMT-PGMKIYIDPFTYEDPNEAVREFAKE 615
           +  ++   C  +    AD    +K  H+ +GH+  PG++ Y+DP TYEDP +AV EFAKE
Sbjct: 560 IYVLIGRFCGYKSKHGAD----EKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKE 615

Query: 616 IDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG 675
           +D + + I++V+GAGEFGEVCSG LKLP K+EI VAIKTLK GYTEKQRRDFL EASIMG
Sbjct: 616 LDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMG 675

Query: 676 QFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMK 735
           QFDHPN+I LEGVVTKS PVMI+TE+MENGSLDSFLR++D QFTVIQLVGMLRGIA+GMK
Sbjct: 676 QFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMK 735

Query: 736 YLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAP 795
           YL+DM YVHRDLAARNIL+NSNLVCKVSDFGLSR LEDD  +  YT+  GGKIPIRWT+P
Sbjct: 736 YLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTSP 793

Query: 796 EAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSAL 855
           EAI YRKFTSASDVWSYGIV+WEVMSYGERPYW+M+NQDVI A+++ YRLPPPMDCP+AL
Sbjct: 794 EAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAAL 853

Query: 856 HQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSF 915
           +QLMLDCWQKDRN+RPKF QIV+ LDK+IRNP SLK +   ++  +  LLD++  D T+F
Sbjct: 854 YQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTF 913

Query: 916 NTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMR 975
            T  +WL  +     KE F    ++S D ++++  +D+ +VGVT+ G QKKI++SI+ + 
Sbjct: 914 RTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALE 973

Query: 976 AQ 977
            Q
Sbjct: 974 TQ 975


>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
          Length = 987

 Score = 1092 bits (2825), Expect = 0.0
 Identities = 543/969 (56%), Positives = 705/969 (72%), Gaps = 15/969 (1%)

Query: 15  LLAAVEETLMDSTTATAELGWMVHPP--SGWEEVSGYDENMNTIRTYQVCNVFES-SQNN 71
           L AA+EETL+++   TA+L W+  P     WEE+SG DE  +++RTY+VC+V  +  Q +
Sbjct: 12  LAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAH 71

Query: 72  WLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWM 131
           WLRT ++ RRGA  ++  ++F++ +C S+P    SCKETF ++YYE+D D+AT   P WM
Sbjct: 72  WLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWM 131

Query: 132 ENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVR 191
           ENP++KVDT+AA+    +        K+N +    GP+S++GFYLAFQD G CM+L+++ 
Sbjct: 132 ENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLH 191

Query: 192 VFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPI-KLYCNGDGEWLV- 249
           +FY+KC ++  N   F ET+       +V   GSC+ +A     P   LYC  DG+W   
Sbjct: 192 LFYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQ 248

Query: 250 PIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGY 309
           P+  C C  GFEA E  T CR C  GTFK   G+ +C  CP NS + + G+  C CR GY
Sbjct: 249 PVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGY 308

Query: 310 YRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGR 369
           +RA  DP   PCTT PSAP++V+S +N +SL LEW+ P +SGGREDL Y + C+ C  G 
Sbjct: 309 FRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPG- 367

Query: 370 GACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNI 429
           G+C  CG ++ + P    L EP + +  L     YTFE+ A+NGV+  +     F  VN+
Sbjct: 368 GSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNV 427

Query: 430 TTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA-IKS 488
           TT++  P AVS +     +  S++L+W+ P  P+G +LDYE++Y+EK     ++   +K+
Sbjct: 428 TTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKT 487

Query: 489 PTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSS 548
             N   ++GLK GA Y+ QVRAR+ AGYG +  + + QT  + +     +E+L LI G++
Sbjct: 488 SENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQT--QLDESEGWREQLALIAGTA 545

Query: 549 AAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEA 608
             G+V ++ V+V+A++C R+     ++EY+DK   Y  GH   G K+YIDPFTYEDPNEA
Sbjct: 546 VVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGH---GTKVYIDPFTYEDPNEA 602

Query: 609 VREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFL 668
           VREFAKEID+S VKIE+VIGAGEFGEVC G LK PGK+E  VAIKTLK GYTE+QRR+FL
Sbjct: 603 VREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFL 662

Query: 669 SEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLR 728
           SEASIMGQF+HPN+I LEGVVT S PVMI+TEFMENG+LDSFLR NDGQFTVIQLVGMLR
Sbjct: 663 SEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLR 722

Query: 729 GIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKI 788
           GIA+GM+YLA+M+YVHRDLAARNILVNSNLVCKVSDFGLSRFLE+++SDPTYTS+LGGKI
Sbjct: 723 GIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKI 782

Query: 789 PIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPP 848
           PIRWTAPEAI +RKFTSASD WSYGIVMWEVMS+GERPYWDM+NQDVINAIEQDYRLPPP
Sbjct: 783 PIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPP 842

Query: 849 MDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRT 908
            DCP++LHQLMLDCWQKDRN RP+F Q+V+ LDKMIRNP SLK +A  + G + PLLD+ 
Sbjct: 843 PDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQR 902

Query: 909 IPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKIL 968
            P Y++F +V EWL AIKMG+Y+ESFA AGF SF++VSQ+  ED+LR+GVTLAGHQKKIL
Sbjct: 903 QPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKIL 962

Query: 969 NSIQVMRAQ 977
            S+Q M++Q
Sbjct: 963 ASVQHMKSQ 971


>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
          Length = 1130

 Score = 1078 bits (2789), Expect = 0.0
 Identities = 537/1006 (53%), Positives = 704/1006 (69%), Gaps = 58/1006 (5%)

Query: 23   LMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIRRRG 82
            L+D+TT   ELGW  +P +GW+ ++  DE+   I TYQVCNV E +QNNWLRT +I R  
Sbjct: 131  LLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNWISRDA 190

Query: 83   AHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVDTIA 142
            A +I+VEMKF++RDC+SIP V G+CKETFNL+Y E+D     K  PN     + K+DTIA
Sbjct: 191  AQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPN----QYTKIDTIA 246

Query: 143  ADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPRIIQ 202
            ADESF+Q+DLG R++K+NTE+R  GP+ R GFYLAFQD G C++L++VRVFY+KCP  ++
Sbjct: 247  ADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVR 306

Query: 203  NGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAGFEA 262
            N A+F +T+   +S+SLV  RGSC+ +AEE D P KLYC  DG+WLVP+GRC+C  G+E 
Sbjct: 307  NLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTP-KLYCGADGDWLVPLGRCICSTGYEE 365

Query: 263  VENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCT 322
            +E    C  C  G +KA  G+  C+ CP +S T  E  + C C  GY+RA+ DP  M CT
Sbjct: 366  IEGS--CHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACT 423

Query: 323  TIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYA 382
              PSAP+ V+ ++NET+L+LEW+PP D+GGR+DL Y++ICK CG     C  CG  +++ 
Sbjct: 424  RPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFI 483

Query: 383  PRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQ-FASVNITTNQAAPSAVSI 441
            PR  GL    + + D ++H  YTFEI+A+NGV++ S FSP+ F ++ +TT+Q APS + +
Sbjct: 484  PRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELS-FSPKPFTAITVTTDQDAPSLIGV 542

Query: 442  MHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLKAG 501
            + +   + +SI LSW  P   NG ILDYE++YYEKE  +   ++ +S   +V + GLK  
Sbjct: 543  VRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPA 602

Query: 502  AIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVVVI 561
              YVF +R RT  GY  YS K  F+T  E     + Q ++ +I  ++  G   L+ + + 
Sbjct: 603  TKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLF 662

Query: 562  AIVCNR-RGFERADSEYTDKLQ-HYTSGHMT-PGMKIYIDPFTYEDPNEAVREFAKEIDI 618
             ++  R + + +A  +  +K + H  +GH+  PG+K YIDP TYEDP+ AV EFAKEID 
Sbjct: 663  FLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDP 722

Query: 619  SCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFD 678
            S ++IE+VIGAGEFGEVCSG LK PGKREI VAIKTLK G+ ++QRRDFL EASIMGQFD
Sbjct: 723  SRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFD 782

Query: 679  HPNVIHLEGVVTKST------------------------------------------PVM 696
            HPN+I LEGVVTK +                                          PVM
Sbjct: 783  HPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVM 842

Query: 697  IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 756
            I+ E+MENGSLDSFLR++DG FTVIQLVGMLRGIA+GMKYL+DM YVHRDLAARNILVNS
Sbjct: 843  IVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNS 902

Query: 757  NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 816
            NLVCKVSDFGLSR LEDD  +  YT+  GGKIPIRWTAPEAI YRKF+SASD WSYGIVM
Sbjct: 903  NLVCKVSDFGLSRVLEDD-PEAAYTTT-GGKIPIRWTAPEAIAYRKFSSASDAWSYGIVM 960

Query: 817  WEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQI 876
            WEVMSYGERPYW+M+NQDVI +IE+ YRLP PM CP++LHQLML CWQK+RNHRPKF  I
Sbjct: 961  WEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDI 1020

Query: 877  VNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFAN 936
            V+ LDK+IRNP++L  +  +   + +P     +P+Y  F TV +WL++IKMGQYK +F  
Sbjct: 1021 VSFLDKLIRNPSALHTL--VEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVA 1078

Query: 937  AGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQ 982
            AGFT+FD++S+M ++DI R+GV L GHQ++I++SIQ +R  M  IQ
Sbjct: 1079 AGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQ 1124


>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
           sapiens]
          Length = 1005

 Score = 1033 bits (2671), Expect = 0.0
 Identities = 509/988 (51%), Positives = 689/988 (69%), Gaps = 44/988 (4%)

Query: 20  EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79
           E  L+D++T   + GW+ +P  GW+ ++  DE+   I TYQVCNV   +QNNWLRT ++ 
Sbjct: 31  EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90

Query: 80  RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139
           R GA R++ E+KF++RDC+S+P V G+CKETFNLYY E+D D    T     E+ ++K+D
Sbjct: 91  RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGAST----QESQFLKID 146

Query: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199
           TIAADESF+  DLG R +K+NTEVRS GP+S+ GFYLAFQD G C++++++R++Y+KCP 
Sbjct: 147 TIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPA 206

Query: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259
           +++N A F E ++GA+S+SLV  RG C+ ++EE D P K+YC+ +GEWLVPIG+C+C AG
Sbjct: 207 MVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTP-KMYCSAEGEWLVPIGKCVCSAG 265

Query: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319
           +E  E    C  C  G +K+  GD+ C  CP +S + +  A  C C   YYRA LDP   
Sbjct: 266 YE--ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSS 323

Query: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379
            CT  PSAP  +ISSVN TS+ LEW PP D GGR D+ YN +C+ C      C  CG   
Sbjct: 324 ACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGT 383

Query: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAV 439
           ++ P+Q  L +  + +++LLAH  Y+F I+AVNGV+D SP   + A VNITTNQAAPS V
Sbjct: 384 RFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQV 443

Query: 440 SIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLK 499
            ++ Q      S++L W +P+QPNG+IL+YE++YYEK+    + + +K+ T   TV GLK
Sbjct: 444 VVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLK 503

Query: 500 AGAIYVFQVRARTVAGYGRYSGKMYFQT---MTEAEYQTSIQEKLPLIIGSSAAGLVFLI 556
            G  YVFQVRART AG GR+S  M  +T       + +T +   L LI G         +
Sbjct: 504 PGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWICLTLITG---------L 554

Query: 557 AVVVIAIVCNRR--GFERADSEYTDKLQHYTSG----------HMTPGM----KIYIDPF 600
            V+++ ++C +R  G+ +A  +  ++  HY +G          H  PG     + Y +P 
Sbjct: 555 VVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPH 614

Query: 601 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 660
           TYE+P  A R F +EI+ S + IE++IG+G+ GEVC G L++PG+R++ VAIK LK+GYT
Sbjct: 615 TYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYT 674

Query: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 720
           E+QRRDFLSEASIMGQFDHPN+I LEGVVT+    MI+TE+MENGSLD+FLR +DGQFT+
Sbjct: 675 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTI 734

Query: 721 IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY 780
           +QLVGMLRG+ AGM+YL+D+ YVHRDLAARN+LV+SNLVCKVSDFGLSR LEDD  D  Y
Sbjct: 735 MQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD-PDAAY 793

Query: 781 TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE 840
           T+  GGKIPIRWTAPEAI +R F+SASDVWS+G+VMWEV++YGERPYW+MTN+DVI+++E
Sbjct: 794 TTT-GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVE 852

Query: 841 QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI 900
           + YRLP PM CP ALHQLMLDCW KDR  RP+F QIV+ LD +IR+P SL+A A +S   
Sbjct: 853 EGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSR-C 911

Query: 901 NLPLLDRTIPDYTSFN------TVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDIL 954
             P   R+  D    +      TV +WL++I+MG+Y++ FA  G++S  +V +M  +D+ 
Sbjct: 912 PPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVR 971

Query: 955 RVGVTLAGHQKKILNSIQVMRAQMNQIQ 982
            +G+TL GHQKKIL SIQ MRAQ+   Q
Sbjct: 972 ALGITLMGHQKKILGSIQTMRAQLTSTQ 999


>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
          Length = 1021

 Score =  935 bits (2417), Expect = 0.0
 Identities = 476/1018 (46%), Positives = 660/1018 (64%), Gaps = 60/1018 (5%)

Query: 10   LLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFES-- 67
            LLL+  + A+EE L+D+T  T+E+GW+ +PP GW+EVS  D+     RT++ C+V  +  
Sbjct: 23   LLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTFEACHVAGAPP 82

Query: 68   --SQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125
               Q+NWL+T F+ RRGA R H+ + FSVR CSS+    G+C+ETF LYY +A+   +  
Sbjct: 83   GTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPDSPD 142

Query: 126  TFPNWMENPWVKVDTIAADESFSQVD-----------------LGGRV-MKINTEVRSFG 167
            +  +W    W KVDTIAADESF                      G R  +++N + RSFG
Sbjct: 143  SVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKERSFG 202

Query: 168  PVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPRIIQNGAIFQET-LSGAESTSLVAARGSC 226
            P+++ GFY+AFQD G C++L+AVR+F   CP ++++ A F ET  SGA   SLVAA G+C
Sbjct: 203  PLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAVGTC 262

Query: 227  IANAEEVD---------VPIKLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTF 277
            +A+AE  +          P +L+CNG+G+W+V +G C C+ G++       C+ CP G +
Sbjct: 263  VAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGLY 322

Query: 278  KANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNE 337
            K++ G+  C+ CP  S   +  A  C C  G+YRA  DP + PCT  PSAPQ +   V  
Sbjct: 323  KSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQG 382

Query: 338  TSLMLEWTPPRDSGGREDLVYNIICKSC-------GSGRGACTRCGDNVQYAPRQLGLTE 390
            ++LML W  PR+ GGR DL++N++CK C         G G C RC D V + PRQ GLTE
Sbjct: 383  SALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTE 442

Query: 391  PRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVD 450
             R+ +  L AH  Y  E+QAVNGV++ SP  PQ A++N++T+   PSAV ++HQVSR  +
Sbjct: 443  SRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRASN 502

Query: 451  SITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRA 510
            SIT+SW QPDQ NG ILDY+L+YY++   E ++  + S TNT TV  L  G IY FQVRA
Sbjct: 503  SITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQVRA 562

Query: 511  RTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFLI--AVVVIAIVCNRR 568
            RT AG+G Y GK+YFQT+ + E  + + E+L L+IGS    L FL+  A+ V+A+V  R+
Sbjct: 563  RTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQRK 622

Query: 569  GFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIG 628
               R  + YT++LQ Y+S  +  G+K YIDP TYEDP +A+RE A+E+D + +KIE+VIG
Sbjct: 623  ---RRGTGYTEQLQQYSSPGL--GVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIG 677

Query: 629  AGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGV 688
             G FGEV  G L+  G+RE  VAI+ L +G  E  +  FL  A+++GQF HPN++ LEGV
Sbjct: 678  TGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGV 737

Query: 689  VTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLA 748
            VTKS P+M++TEFME G LDSFLRQ +GQF+ +QLV M RG+AA M+YL+   +VHR L+
Sbjct: 738  VTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLS 797

Query: 749  ARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASD 808
            A ++LVNS+LVCKV+  G S         P   S L     +RW APE I + K T++SD
Sbjct: 798  AHSVLVNSHLVCKVARLGHS---------PQGPSCL-----LRWAAPEVIAHGKHTTSSD 843

Query: 809  VWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRN 868
            VWS+GI+MWEVMSYGERPYWDM+ Q+V+NAIEQ++RLPPP  CP  LH LMLD WQKDR 
Sbjct: 844  VWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRA 903

Query: 869  HRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMG 928
             RP F Q+V   DKMIR P++L+A        +  LL     D+   ++   WL AI + 
Sbjct: 904  RRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLE 963

Query: 929  QYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQSVEV 986
             Y+++F+  G  +F  V+Q+ +ED+  +G+TLAGHQKK+L+ IQ+++  + Q  SVEV
Sbjct: 964  CYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSVEV 1021


>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
          Length = 976

 Score =  905 bits (2338), Expect = 0.0
 Identities = 478/983 (48%), Positives = 639/983 (65%), Gaps = 33/983 (3%)

Query: 7   GAALLLLPLLAAVEETLMDSTTATAELGWMVHP-PSGWEEVSGYDENMNTIRTYQVCNVF 65
           G AL         E  L+D   A  ELGW+ HP   GW+ +     +M  I  Y VCNV 
Sbjct: 15  GCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVM 73

Query: 66  ESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125
              Q+NWLRT ++ R  A RI +E+KF+VRDC+S P    SCKETFNLYY E+D D  T 
Sbjct: 74  SGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGT- 132

Query: 126 TFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCM 185
              N+ +  + K+DTIA DE     D   R +K+N E RS GP++R GFYLAFQD G C+
Sbjct: 133 ---NFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACV 189

Query: 186 SLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPI-----KLY 240
           +L++VRV+Y+KCP ++Q  A F ET++G+++ SL    G+C+ +A    VP      +++
Sbjct: 190 ALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAV---VPPGGEEPRMH 246

Query: 241 CNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGA 300
           C  DGEWLVPIG+C+C+AG+E VE+   C+ C  G FK    +  C  CP ++  + EGA
Sbjct: 247 CAVDGEWLVPIGQCLCQAGYEKVEDA--CQACSPGFFKFEASESPCLECPEHTLPSPEGA 304

Query: 301 TNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNI 360
           T+C C  G++RA  DP  MPCT  PSAP  + +      + L WTPP+DSGGRED+VY++
Sbjct: 305 TSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSV 364

Query: 361 ICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPF 420
            C+ C    G C  C  +V+Y+    GLT   + +SDL  H  YTF ++A NGV+     
Sbjct: 365 TCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT- 423

Query: 421 SPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEK-ELS 479
           S  F + +++ NQ  P  V +     R+  S+++SWS P      +  YE+ Y +K + +
Sbjct: 424 SRSFRTASVSINQTEPPKVRLE---GRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN 480

Query: 480 EYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQE 539
            YN    ++   +VT+  L     Y+ QV+A T  G G  S    FQT++  E   ++  
Sbjct: 481 SYNVR--RTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSP-EGSGNLA- 536

Query: 540 KLPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDP 599
               +IG  A G+V L+ +  +    +RR   +   +  + +    S  + P +K Y+DP
Sbjct: 537 ----VIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKP-LKTYVDP 591

Query: 600 FTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLP-GKREIFVAIKTLKSG 658
            TYEDPN+AV +F  EI  SCV  ++VIGAGEFGEV  G LK   GK+E+ VAIKTLK+G
Sbjct: 592 HTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAG 651

Query: 659 YTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQF 718
           YTEKQR DFL EA IMGQF H N+I LEGV++K  P+MIITE+MENG+LD FLR+ DG+F
Sbjct: 652 YTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEF 711

Query: 719 TVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDP 778
           +V+QLVGMLRGIAAGMKYLA+MNYVHRDLAARNILVNSNLVCKVSDFGLSR LEDD  + 
Sbjct: 712 SVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDP-EA 770

Query: 779 TYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINA 838
           TYT++ GGKIPIRWTAPEAI YRKFTSASDVWS+GIVMWEVM+YGERPYW+++N +V+ A
Sbjct: 771 TYTTS-GGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKA 829

Query: 839 IEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSS 898
           I   +RLP PMDCPSA++QLM+ CWQ++R  RPKF  IV+ LDK+IR P+SLK +A    
Sbjct: 830 INDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDP 889

Query: 899 GINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGV 958
            +++ L   +  +   F TV EWLE+IKM QY E F  AG+T+ + V QM  +DI R+GV
Sbjct: 890 RVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGV 949

Query: 959 TLAGHQKKILNSIQVMRAQMNQI 981
            L GHQK+I  S+  ++ Q+N +
Sbjct: 950 RLPGHQKRIAYSLLGLKDQVNTV 972


>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
          Length = 1008

 Score =  810 bits (2092), Expect = 0.0
 Identities = 423/993 (42%), Positives = 621/993 (62%), Gaps = 23/993 (2%)

Query: 5    RLGAALLLLPLL--AAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVC 62
            +L  ALLL P     A E  L+DS  + AELGW   P +GWEE+SG DE+   IRTYQVC
Sbjct: 18   QLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVC 77

Query: 63   NVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDS 122
            NV E +Q+NWL+T +I R    RI VE++F++RDCSSIP   G+CKETFN+YY E + D 
Sbjct: 78   NVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADL 137

Query: 123  ATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYG 182
              +  P    +   K+DTIAADESF+Q DLG R MK+NTEVR  GP+SR GF+LAFQD G
Sbjct: 138  G-RGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVG 196

Query: 183  GCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAE-EVDVPIKLYC 241
             C++L++VRV+Y++C   ++  A F  T + +  ++LV   G+C+A++E E   P +++C
Sbjct: 197  ACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHC 256

Query: 242  NGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGAT 301
              DGEWLVP+GRC C AGF+  E G  C  CP G +K +     C+ CP +SR     +T
Sbjct: 257  GADGEWLVPVGRCSCSAGFQ--ERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENAST 314

Query: 302  NCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLE--WTPPRDSGGREDLVYN 359
             CVC++ Y R+  DP    CT  PSAP+ +  S++ + L+L   W PP DSGGR D+ Y+
Sbjct: 315  FCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYS 374

Query: 360  IICKSCG--SGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQ 417
            ++C  CG     GAC  CG  V + PRQ GL E    +  L    +YT  + A+NGV+  
Sbjct: 375  LLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGP 434

Query: 418  SPFS-PQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQP---DQPNGVILDYELQY 473
            +  +   +A V ++T   AP     + +      S++LSW +P     P     +YE++Y
Sbjct: 435  AAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRY 494

Query: 474  YEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGR---YSGKMYFQTMTE 530
            YEK  SE   + +K+   TVTV  LK    YVFQ+RA +         ++  +  QT+ E
Sbjct: 495  YEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGE 554

Query: 531  AEYQTSIQEKLPLIIGSSAAGLVFLIAVVVIAIVCNRR-GFERADSEYTDKLQHYTSGHM 589
            A   +  Q    ++   + + L+ L +V+ +  +  R   + +   +  D+ + Y     
Sbjct: 555  AASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEELYFH-FK 613

Query: 590  TPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIF 649
             P  + ++DP +  D  +AV  FAKE+D   V +E+ +G G FGE+C G L+LPG++E+ 
Sbjct: 614  VPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELL 673

Query: 650  VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
            VA+  L+   ++ QR  FL+EA  +GQFDH +++ LEGVVT+ + +MI+TE+M +G+LD 
Sbjct: 674  VAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDG 733

Query: 710  FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSR 769
            FLR+++GQ    QL+G+L G+A+ MKYL++M YVHR LAAR++LV+S+LVCK+S FG   
Sbjct: 734  FLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRG- 792

Query: 770  FLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWD 829
                D S+  YT+ + G+ P  W APE +Q+  F+SASDVWS+GI+MWEVM++GERPYWD
Sbjct: 793  --PRDRSEAVYTT-MSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWD 849

Query: 830  MTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNS 889
            M+ QDVI A+E  +RLPPP +CP+ LH+LMLDCWQKD   RP+F QI + L KM+++P  
Sbjct: 850  MSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEP 909

Query: 890  LKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMM 949
             K           PL DR    + SF +V  WLEA+ + +YK+SFA AG+ S + V++M 
Sbjct: 910  PKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMT 969

Query: 950  MEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQ 982
             +D++ +G++LA H++ +L+ I  ++A++ Q+Q
Sbjct: 970  AQDLVSLGISLAEHREALLSGISALQARVLQLQ 1002


>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
          Length = 976

 Score =  722 bits (1863), Expect = 0.0
 Identities = 414/985 (42%), Positives = 581/985 (58%), Gaps = 39/985 (3%)

Query: 6   LGAALLLL----PLLAAVEETLMDSTTATAELGWMVHPPS-GWEEVSGYDENMNTIRTYQ 60
           LG  LLL     P   A E TLMD++ A  ELGW++ PP  GW E      N   +  YQ
Sbjct: 9   LGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLYMYQ 67

Query: 61  VCNVF-ESSQNNWLRTKFIRR-RGAHRIHVEMKFSVRDCSSIPSVPG--SCKETFNLYYY 116
            C +      ++WLR+ +I R   A R+HVE++F+VRDC S P   G   CKETFNL Y 
Sbjct: 68  DCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYM 127

Query: 117 EADFDSATKTFPNWMENP-WVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFY 175
           E+D D   +     +  P + KV T+AAD+SF+  DL    +K+N E  S G ++R G Y
Sbjct: 128 ESDQDVGIQ-----LRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLY 182

Query: 176 LAFQDYGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDV 235
           LAF + G C++L++VRVFY++CP  +   A F +TL G     LV   G+C+ +A     
Sbjct: 183 LAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARASPR 240

Query: 236 PI---KLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPIN 292
           P    +++C+ DGEWLVP+GRC C+ G+E   +G  C  CPSG+++ +     C  CP  
Sbjct: 241 PSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQ 300

Query: 293 SRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGG 352
           S   SEGAT C C +G+YRA  +   + CT  PSAP+ +  S + T L L W PP D+GG
Sbjct: 301 STAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGG 360

Query: 353 REDLVYNIICKSC---GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQ 409
           R+D+ Y++ C  C       G C  CG  V ++P   GLT P ++++ L  +  YTF ++
Sbjct: 361 RQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVE 420

Query: 410 AVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSW--SQPDQPNGVIL 467
           A NGV+          SV+I+   A   +   +  V +    + L+W  S+P  P G  L
Sbjct: 421 AQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANL 479

Query: 468 DYELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQT 527
            YEL    ++   Y    +  P   V +  L+    Y+ +VR  T  G G +S    F+T
Sbjct: 480 TYELHVLNQDEERYQM--VLEPR--VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRT 535

Query: 528 MTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSG 587
                   +  E + +I G      + L  +V  +    R+  +R     TD        
Sbjct: 536 SPPVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATD-----VDR 590

Query: 588 HMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKRE 647
                +K Y+D   YEDP +   +F +E+D + + ++ VIG GEFGEV  G L+LP +  
Sbjct: 591 EDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDC 650

Query: 648 IFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSL 707
             VAIKTLK      Q  +FL EA+IMGQF HP+++HLEGVVTK  P+MIITEFMENG+L
Sbjct: 651 KTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGAL 710

Query: 708 DSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGL 767
           D+FLR+ + Q    QLV ML+GIA+GM YL++ NYVHRDLAARNILVN NL CKVSDFGL
Sbjct: 711 DAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGL 770

Query: 768 SRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPY 827
           +R L+D   D TY +  GGKIPIRWTAPEAI +R FT+ASDVWS+GIVMWEV+S+G++PY
Sbjct: 771 TRLLDD--FDGTYETQ-GGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPY 827

Query: 828 WDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 887
            +M+NQ+V+ +IE  YRLPPP+DCP+ L++LM +CW  DR  RP F ++   L++++ NP
Sbjct: 828 GEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANP 887

Query: 888 NSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQ 947
           +SL+ +A     + L L   +  D   + TV EWLE+I+M +Y   F +AG  + + V +
Sbjct: 888 HSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLE 947

Query: 948 MMMEDILRVGVTLAGHQKKILNSIQ 972
           +  ED+ ++G+TL GHQK+IL SIQ
Sbjct: 948 LTAEDLTQMGITLPGHQKRILCSIQ 972


>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
           sapiens]
          Length = 539

 Score =  569 bits (1467), Expect = e-162
 Identities = 270/514 (52%), Positives = 368/514 (71%), Gaps = 8/514 (1%)

Query: 20  EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79
           E  L+DS T   ELGW+ +P  GWEE+SG DE+   IRTYQVCNV + SQNNWLRT ++ 
Sbjct: 29  EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88

Query: 80  RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139
           R  A +I+VE+KF++RDC+SIP V G+CKETFNLYY E+D D   K    + E+ + K+D
Sbjct: 89  RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144

Query: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199
           TIAADESF+Q+DLG R++K+NTE+R  GPV++ GFYLAFQD G C++L++VRV+++KCP 
Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204

Query: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259
            ++N A+F +T+   +S SLV  RGSC+ N++E D P ++YC+ +GEWLVPIG+C C AG
Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262

Query: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319
           +E  E G +C+ C  G +KA  G+  C  CP +S T  +G+ NC C N Y+RAD DP  M
Sbjct: 263 YE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320

Query: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379
            CT  PS+P+ VIS++NETS++L+W+ P D+GGR+D+ +NIICK CG     C  C  NV
Sbjct: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNV 380

Query: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAV 439
           ++ PRQ GLT   + ++DLLAHT YTFEI AVNGV++ S    QFA+V+ITTNQAAPS V
Sbjct: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV 440

Query: 440 SIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLK 499
             + +   + +SI+LSW +P+ PNG+ILDYE++YYEK+  E + T +++    VT+  LK
Sbjct: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500

Query: 500 AGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEY 533
              IYVFQ+RART AGYG  S K  F+T  +  Y
Sbjct: 501 PDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534


>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
           sapiens]
          Length = 495

 Score =  441 bits (1134), Expect = e-123
 Identities = 204/415 (49%), Positives = 283/415 (68%), Gaps = 7/415 (1%)

Query: 20  EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79
           E  L+D++T   + GW+ +P  GW+ ++  DE+   I TYQVCNV   +QNNWLRT ++ 
Sbjct: 31  EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90

Query: 80  RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139
           R GA R++ E+KF++RDC+S+P V G+CKETFNLYY E+D D    T     E+ ++K+D
Sbjct: 91  RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGAST----QESQFLKID 146

Query: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199
           TIAADESF+  DLG R +K+NTEVRS GP+S+ GFYLAFQD G C++++++R++Y+KCP 
Sbjct: 147 TIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPA 206

Query: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259
           +++N A F E ++GA+S+SLV  RG C+ ++EE D P K+YC+ +GEWLVPIG+C+C AG
Sbjct: 207 MVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTP-KMYCSAEGEWLVPIGKCVCSAG 265

Query: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319
           +E  E    C  C  G +K+  GD+ C  CP +S + +  A  C C   YYRA LDP   
Sbjct: 266 YE--ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSS 323

Query: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379
            CT  PSAP  +ISSVN TS+ LEW PP D GGR D+ YN +C+ C      C  CG   
Sbjct: 324 ACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGT 383

Query: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQA 434
           ++ P+Q  L +  + +++LLAH  Y+F I+AVNGV+D SP   + A VNITTNQA
Sbjct: 384 RFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQA 438


>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
          Length = 295

 Score =  267 bits (682), Expect = 4e-71
 Identities = 137/270 (50%), Positives = 183/270 (67%), Gaps = 6/270 (2%)

Query: 5   RLGAALLLLPLL--AAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVC 62
           +L  ALLL P     A E  L+DS  + AELGW   P +GWEE+SG DE+   IRTYQVC
Sbjct: 18  QLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVC 77

Query: 63  NVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDS 122
           NV E +Q+NWL+T +I R    RI VE++F++RDCSSIP   G+CKETFN+YY E + D 
Sbjct: 78  NVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADL 137

Query: 123 ATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYG 182
             +  P    +   K+DTIAADESF+Q DLG R MK+NTEVR  GP+SR GF+LAFQD G
Sbjct: 138 G-RGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVG 196

Query: 183 GCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAE-EVDVPIKLYC 241
            C++L++VRV+Y++C   ++  A F  T + +  ++LV   G+C+A++E E   P +++C
Sbjct: 197 ACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHC 256

Query: 242 NGDGEWLVPIGRCMCKAGFEAVENGTVCRG 271
             DGEWLVP+GRC C AGF+  E G  C G
Sbjct: 257 GADGEWLVPVGRCSCSAGFQ--ERGDFCEG 284


>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
          Length = 526

 Score =  228 bits (580), Expect = 3e-59
 Identities = 126/308 (40%), Positives = 184/308 (59%), Gaps = 13/308 (4%)

Query: 575 SEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGE 634
           S   + + HY  G+     K+ + P     P +   + A EI    +K+E+ +GAG+FGE
Sbjct: 217 STLQELVDHYKKGNDGLCQKLSV-PCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGE 275

Query: 635 VCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTP 694
           V         K    VA+KT+K G    +   FL+EA++M    H  ++ L  VVTK  P
Sbjct: 276 VWMATYNKHTK----VAVKTMKPGSMSVEA--FLAEANVMKTLQHDKLVKLHAVVTKE-P 328

Query: 695 VMIITEFMENGSLDSFLRQNDGQFTVI-QLVGMLRGIAAGMKYLADMNYVHRDLAARNIL 753
           + IITEFM  GSL  FL+ ++G    + +L+     IA GM ++   NY+HRDL A NIL
Sbjct: 329 IYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANIL 388

Query: 754 VNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYG 813
           V+++LVCK++DFGL+R +ED+     YT+  G K PI+WTAPEAI +  FT  SDVWS+G
Sbjct: 389 VSASLVCKIADFGLARVIEDNE----YTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFG 444

Query: 814 IVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKF 873
           I++ E+++YG  PY  M+N +VI A+E+ YR+P P +CP  L+ +M+ CW+     RP F
Sbjct: 445 ILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTF 504

Query: 874 GQIVNTLD 881
             I + LD
Sbjct: 505 EYIQSVLD 512


>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
          Length = 543

 Score =  226 bits (577), Expect = 6e-59
 Identities = 134/312 (42%), Positives = 185/312 (59%), Gaps = 13/312 (4%)

Query: 572 RADSEYTDKL-QHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAG 630
           RA  +   KL +HYT        K+     T +   + + + A EI    +++E  +G G
Sbjct: 227 RAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQG 286

Query: 631 EFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVT 690
            FGEV  G      K    VAIKTLK G    +   FL EA IM +  H  ++ L  VV+
Sbjct: 287 CFGEVWMGTWNGTTK----VAIKTLKPGTMMPEA--FLQEAQIMKKLRHDKLVPLYAVVS 340

Query: 691 KSTPVMIITEFMENGSLDSFLRQNDGQFTVI-QLVGMLRGIAAGMKYLADMNYVHRDLAA 749
           +  P+ I+TEFM  GSL  FL++ DG++  + QLV M   IA GM Y+  MNY+HRDL A
Sbjct: 341 EE-PIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRA 399

Query: 750 RNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDV 809
            NILV  NLVCK++DFGL+R +ED+     YT+  G K PI+WTAPEA  Y +FT  SDV
Sbjct: 400 ANILVGENLVCKIADFGLARLIEDNE----YTARQGAKFPIKWTAPEAALYGRFTIKSDV 455

Query: 810 WSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNH 869
           WS+GI+  E+++ G  PY  M N++V+  +E+ YR+P P  CP +LH+LM  CW+KD + 
Sbjct: 456 WSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDE 515

Query: 870 RPKFGQIVNTLD 881
           RP F  I + L+
Sbjct: 516 RPTFEYIQSFLE 527


>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
          Length = 1074

 Score =  223 bits (567), Expect = 9e-58
 Identities = 126/313 (40%), Positives = 180/313 (57%), Gaps = 10/313 (3%)

Query: 573 ADSEYTDKLQHYTSGHMTPGMKIYIDPF-TYEDPNEAVREFAKEIDISCVKIEQVIGAGE 631
           A+SE      H  S   T      ID   TY  P+   R++  EI    +++ + IG G+
Sbjct: 399 ANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPS--TRDY--EIQRERIELGRCIGEGQ 454

Query: 632 FGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTK 691
           FG+V  G    P    + VAIKT K+  ++  R  FL EA  M QFDHP+++ L GV+T+
Sbjct: 455 FGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITE 514

Query: 692 STPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARN 751
           + PV II E    G L SFL+       +  L+     ++  + YL    +VHRD+AARN
Sbjct: 515 N-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARN 573

Query: 752 ILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWS 811
           +LV+SN   K+ DFGLSR++ED T    Y  A  GK+PI+W APE+I +R+FTSASDVW 
Sbjct: 574 VLVSSNDCVKLGDFGLSRYMEDST----YYKASKGKLPIKWMAPESINFRRFTSASDVWM 629

Query: 812 YGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRP 871
           +G+ MWE++ +G +P+  + N DVI  IE   RLP P +CP  L+ LM  CW  D + RP
Sbjct: 630 FGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRP 689

Query: 872 KFGQIVNTLDKMI 884
           +F ++   L  ++
Sbjct: 690 RFTELKAQLSTIL 702


>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
          Length = 1052

 Score =  223 bits (567), Expect = 9e-58
 Identities = 126/313 (40%), Positives = 180/313 (57%), Gaps = 10/313 (3%)

Query: 573 ADSEYTDKLQHYTSGHMTPGMKIYIDPF-TYEDPNEAVREFAKEIDISCVKIEQVIGAGE 631
           A+SE      H  S   T      ID   TY  P+   R++  EI    +++ + IG G+
Sbjct: 377 ANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPS--TRDY--EIQRERIELGRCIGEGQ 432

Query: 632 FGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTK 691
           FG+V  G    P    + VAIKT K+  ++  R  FL EA  M QFDHP+++ L GV+T+
Sbjct: 433 FGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITE 492

Query: 692 STPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARN 751
           + PV II E    G L SFL+       +  L+     ++  + YL    +VHRD+AARN
Sbjct: 493 N-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARN 551

Query: 752 ILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWS 811
           +LV+SN   K+ DFGLSR++ED T    Y  A  GK+PI+W APE+I +R+FTSASDVW 
Sbjct: 552 VLVSSNDCVKLGDFGLSRYMEDST----YYKASKGKLPIKWMAPESINFRRFTSASDVWM 607

Query: 812 YGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRP 871
           +G+ MWE++ +G +P+  + N DVI  IE   RLP P +CP  L+ LM  CW  D + RP
Sbjct: 608 FGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRP 667

Query: 872 KFGQIVNTLDKMI 884
           +F ++   L  ++
Sbjct: 668 RFTELKAQLSTIL 680


>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform B [Homo sapiens]
          Length = 491

 Score =  222 bits (566), Expect = 1e-57
 Identities = 116/270 (42%), Positives = 169/270 (62%), Gaps = 11/270 (4%)

Query: 613 AKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEAS 672
           A EI    +K+ + +GAG+FGEV  G+     K    VA+KTLK G    Q   FL EA+
Sbjct: 218 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 271

Query: 673 IMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVI-QLVGMLRGIA 731
           +M    H  ++ L  VVT+  P+ IITE+M  GSL  FL+ ++G   ++ +L+     IA
Sbjct: 272 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 331

Query: 732 AGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIR 791
            GM Y+   NY+HRDL A N+LV+ +L+CK++DFGL+R +ED+     YT+  G K PI+
Sbjct: 332 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE----YTAREGAKFPIK 387

Query: 792 WTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDC 851
           WTAPEAI +  FT  SDVWS+GI+++E+++YG+ PY   TN DV+ A+ Q YR+P   +C
Sbjct: 388 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENC 447

Query: 852 PSALHQLMLDCWQKDRNHRPKFGQIVNTLD 881
           P  L+ +M  CW++    RP F  + + LD
Sbjct: 448 PDELYDIMKMCWKEKAEERPTFDYLQSVLD 477


>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform A [Homo sapiens]
          Length = 512

 Score =  222 bits (566), Expect = 1e-57
 Identities = 116/270 (42%), Positives = 169/270 (62%), Gaps = 11/270 (4%)

Query: 613 AKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEAS 672
           A EI    +K+ + +GAG+FGEV  G+     K    VA+KTLK G    Q   FL EA+
Sbjct: 239 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 292

Query: 673 IMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVI-QLVGMLRGIA 731
           +M    H  ++ L  VVT+  P+ IITE+M  GSL  FL+ ++G   ++ +L+     IA
Sbjct: 293 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 352

Query: 732 AGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIR 791
            GM Y+   NY+HRDL A N+LV+ +L+CK++DFGL+R +ED+     YT+  G K PI+
Sbjct: 353 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE----YTAREGAKFPIK 408

Query: 792 WTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDC 851
           WTAPEAI +  FT  SDVWS+GI+++E+++YG+ PY   TN DV+ A+ Q YR+P   +C
Sbjct: 409 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENC 468

Query: 852 PSALHQLMLDCWQKDRNHRPKFGQIVNTLD 881
           P  L+ +M  CW++    RP F  + + LD
Sbjct: 469 PDELYDIMKMCWKEKAEERPTFDYLQSVLD 498


>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
          Length = 537

 Score =  221 bits (564), Expect = 2e-57
 Identities = 117/268 (43%), Positives = 169/268 (63%), Gaps = 12/268 (4%)

Query: 615 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 674
           EI    +++ + +G G+FGEV  G      K    VAIKTLK G    +   FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIM 318

Query: 675 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVI-QLVGMLRGIAAG 733
            +  H  ++ L  VV++  P+ I+TE+M  GSL  FL+  +G+   +  LV M   +AAG
Sbjct: 319 KKLKHDKLVQLYAVVSEE-PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377

Query: 734 MKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWT 793
           M Y+  MNY+HRDL + NILV + L+CK++DFGL+R +ED+     YT+  G K PI+WT
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE----YTARQGAKFPIKWT 433

Query: 794 APEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPS 853
           APEA  Y +FT  SDVWS+GI++ E+++ G  PY  M N++V+  +E+ YR+P P DCP 
Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPI 493

Query: 854 ALHQLMLDCWQKDRNHRPKFGQIVNTLD 881
           +LH+LM+ CW+KD   RP F  + + L+
Sbjct: 494 SLHELMIHCWKKDPEERPTFEYLQSFLE 521


>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score =  221 bits (563), Expect = 3e-57
 Identities = 125/303 (41%), Positives = 185/303 (61%), Gaps = 15/303 (4%)

Query: 581 LQHYTSGHMTPGMKIYID-PFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGH 639
           ++HYT+   + G+   +  P   + P +   E   E+    +K+ + +GAG+FGEV  G+
Sbjct: 206 VRHYTNA--SDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGY 263

Query: 640 LKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIIT 699
                K    VA+K+LK G        FL+EA++M Q  H  ++ L  VVT+  P+ IIT
Sbjct: 264 YNGHTK----VAVKSLKQGSMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQE-PIYIIT 316

Query: 700 EFMENGSLDSFLRQNDG-QFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNL 758
           E+MENGSL  FL+   G + T+ +L+ M   IA GM ++ + NY+HRDL A NILV+  L
Sbjct: 317 EYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTL 376

Query: 759 VCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWE 818
            CK++DFGL+R +ED+     YT+  G K PI+WTAPEAI Y  FT  SDVWS+GI++ E
Sbjct: 377 SCKIADFGLARLIEDNE----YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTE 432

Query: 819 VMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVN 878
           ++++G  PY  MTN +VI  +E+ YR+  P +CP  L+QLM  CW++    RP F  + +
Sbjct: 433 IVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRS 492

Query: 879 TLD 881
            L+
Sbjct: 493 VLE 495


>gi|112789546 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score =  221 bits (563), Expect = 3e-57
 Identities = 125/303 (41%), Positives = 185/303 (61%), Gaps = 15/303 (4%)

Query: 581 LQHYTSGHMTPGMKIYID-PFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGH 639
           ++HYT+   + G+   +  P   + P +   E   E+    +K+ + +GAG+FGEV  G+
Sbjct: 206 VRHYTNA--SDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGY 263

Query: 640 LKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIIT 699
                K    VA+K+LK G        FL+EA++M Q  H  ++ L  VVT+  P+ IIT
Sbjct: 264 YNGHTK----VAVKSLKQGSMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQE-PIYIIT 316

Query: 700 EFMENGSLDSFLRQNDG-QFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNL 758
           E+MENGSL  FL+   G + T+ +L+ M   IA GM ++ + NY+HRDL A NILV+  L
Sbjct: 317 EYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTL 376

Query: 759 VCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWE 818
            CK++DFGL+R +ED+     YT+  G K PI+WTAPEAI Y  FT  SDVWS+GI++ E
Sbjct: 377 SCKIADFGLARLIEDNE----YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTE 432

Query: 819 VMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVN 878
           ++++G  PY  MTN +VI  +E+ YR+  P +CP  L+QLM  CW++    RP F  + +
Sbjct: 433 IVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRS 492

Query: 879 TLD 881
            L+
Sbjct: 493 VLE 495


>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score =  220 bits (561), Expect = 4e-57
 Identities = 121/274 (44%), Positives = 169/274 (61%), Gaps = 12/274 (4%)

Query: 601 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 660
           T +   + + + A EI    +++E  +G G FGEV  G      +    VAIKTLK G  
Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305

Query: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 720
             +   FL EA +M +  H  ++ L  VV++  P+ I+TE+M  GSL  FL+   G++  
Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSEE-PIYIVTEYMSKGSLLDFLKGETGKYLR 362

Query: 721 I-QLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT 779
           + QLV M   IA+GM Y+  MNYVHRDL A NILV  NLVCKV+DFGL+R +ED+     
Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---- 418

Query: 780 YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAI 839
           YT+  G K PI+WTAPEA  Y +FT  SDVWS+GI++ E+ + G  PY  M N++V++ +
Sbjct: 419 YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV 478

Query: 840 EQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKF 873
           E+ YR+P P +CP +LH LM  CW+K+   RP F
Sbjct: 479 ERGYRMPCPPECPESLHDLMCQCWRKEPEERPTF 512


>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score =  220 bits (561), Expect = 4e-57
 Identities = 121/274 (44%), Positives = 169/274 (61%), Gaps = 12/274 (4%)

Query: 601 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 660
           T +   + + + A EI    +++E  +G G FGEV  G      +    VAIKTLK G  
Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305

Query: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 720
             +   FL EA +M +  H  ++ L  VV++  P+ I+TE+M  GSL  FL+   G++  
Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSEE-PIYIVTEYMSKGSLLDFLKGETGKYLR 362

Query: 721 I-QLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT 779
           + QLV M   IA+GM Y+  MNYVHRDL A NILV  NLVCKV+DFGL+R +ED+     
Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---- 418

Query: 780 YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAI 839
           YT+  G K PI+WTAPEA  Y +FT  SDVWS+GI++ E+ + G  PY  M N++V++ +
Sbjct: 419 YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV 478

Query: 840 EQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKF 873
           E+ YR+P P +CP +LH LM  CW+K+   RP F
Sbjct: 479 ERGYRMPCPPECPESLHDLMCQCWRKEPEERPTF 512


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,798,019
Number of Sequences: 37866
Number of extensions: 1646539
Number of successful extensions: 7473
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 602
Number of HSP's successfully gapped in prelim test: 348
Number of HSP's that attempted gapping in prelim test: 3918
Number of HSP's gapped (non-prelim): 2122
length of query: 986
length of database: 18,247,518
effective HSP length: 112
effective length of query: 874
effective length of database: 14,006,526
effective search space: 12241703724
effective search space used: 12241703724
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.