Guide to the Human Genome
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Name: SRC Sequence: fasta or formatted (536aa) NCBI GI: 38202217
Description:

proto-oncogene tyrosine-protein kinase SRC

Referenced in:

Cytoskeleton
Domain Structure of Proteins
Retroviral Oncogene Homologs
Rho and Rac
Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt mRNA [536aa] proto-oncogene tyrosine-protein kinase SRC
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.2         44           3
 C cysteine            1.7          9           1
 D aspartate           3.9         21           1
 E glutamate           7.8         42           2
 F phenylalanine       3.9         21           1
 G glycine             8.0         43           3
 H histidine           1.7          9           1
 I isoleucine          3.0         16           1
 K lysine              5.8         31           2
 L leucine             9.1         49           3
 M methionine          2.1         11           1
 N asparagine          3.4         18           2
 P proline             6.0         32           2
 Q glutamine           4.3         23           2
 R arginine            6.0         32           3
 S serine              6.9         37           2
 T threonine           6.7         36           2
 V valine              5.6         30           2
 W tryptophan          1.7          9           2
 Y tyrosine            4.3         23           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   proto-oncogene tyrosine-protein kinase SRC 
SRC                   1.000   proto-oncogene tyrosine-protein kinase SRC 
YES1                  0.741   viral oncogene yes-1 homolog 1 
FYN                   0.689   protein-tyrosine kinase fyn isoform b 
FYN                   0.672   protein-tyrosine kinase fyn isoform a 
FGR                   0.645   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.645   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.645   proto-oncogene tyrosine-protein kinase FGR 
FYN                   0.601   protein-tyrosine kinase fyn isoform c 
HCK                   0.525   hemopoietic cell kinase isoform p61HCK 
LCK                   0.505   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.505   lymphocyte-specific protein tyrosine kinase precurs...
LYN                   0.500   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
LYN                   0.500   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
BLK                   0.493   B lymphoid tyrosine kinase 
FRK                   0.414   fyn-related kinase 
PTK6                  0.326   PTK6 protein tyrosine kinase 6 
ABL1                  0.317   c-abl oncogene 1, receptor tyrosine kinase isoform b...
ABL1                  0.316   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL2                  0.312   arg tyrosine kinase isoform c 
ABL2                  0.312   arg tyrosine kinase isoform b 
ABL2                  0.312   arg tyrosine kinase isoform e 
ABL2                  0.312   arg tyrosine kinase isoform d 
ABL2                  0.312   arg tyrosine kinase isoform a 
SRMS                  0.307   src-related kinase lacking C-terminal regulatory tyr...
TXK                   0.283   TXK tyrosine kinase 
TEC                   0.277   tec protein tyrosine kinase 
BTK                   0.274   Bruton agammaglobulinemia tyrosine kinase 
ITK                   0.261   IL2-inducible T-cell kinase 
CSK                   0.251   c-src tyrosine kinase 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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