Guide to the Human Genome
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Name: LCK Sequence: fasta or formatted (509aa) NCBI GI: 112789548
Description:

lymphocyte-specific protein tyrosine kinase precursor

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt mRNA [509aa] lymphocyte-specific protein tyrosine kinase precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5         28           2
 C cysteine            1.8          9           1
 D aspartate           5.1         26           2
 E glutamate           8.6         44           2
 F phenylalanine       4.3         22           2
 G glycine             7.3         37           2
 H histidine           2.4         12           1
 I isoleucine          5.5         28           2
 K lysine              4.5         23           1
 L leucine             9.6         49           2
 M methionine          2.2         11           1
 N asparagine          4.7         24           1
 P proline             6.3         32           2
 Q glutamine           4.5         23           1
 R arginine            5.7         29           1
 S serine              5.9         30           2
 T threonine           5.3         27           2
 V valine              4.9         25           2
 W tryptophan          2.2         11           2
 Y tyrosine            3.7         19           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   lymphocyte-specific protein tyrosine kinase precurs... 
LCK                   1.000   lymphocyte-specific protein tyrosine kinase precurs...
HCK                   0.640   hemopoietic cell kinase isoform p61HCK 
LYN                   0.629   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
LYN                   0.629   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
BLK                   0.590   B lymphoid tyrosine kinase 
FYN                   0.544   protein-tyrosine kinase fyn isoform a 
YES1                  0.541   viral oncogene yes-1 homolog 1 
FYN                   0.527   protein-tyrosine kinase fyn isoform b 
SRC                   0.524   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.524   proto-oncogene tyrosine-protein kinase SRC 
FGR                   0.512   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.512   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.512   proto-oncogene tyrosine-protein kinase FGR 
FYN                   0.470   protein-tyrosine kinase fyn isoform c 
FRK                   0.411   fyn-related kinase 
SRMS                  0.331   src-related kinase lacking C-terminal regulatory tyr...
ABL1                  0.324   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.324   c-abl oncogene 1, receptor tyrosine kinase isoform b...
ABL2                  0.323   arg tyrosine kinase isoform c 
ABL2                  0.323   arg tyrosine kinase isoform b 
ABL2                  0.323   arg tyrosine kinase isoform e 
ABL2                  0.323   arg tyrosine kinase isoform d 
ABL2                  0.323   arg tyrosine kinase isoform a 
PTK6                  0.310   PTK6 protein tyrosine kinase 6 
BTK                   0.295   Bruton agammaglobulinemia tyrosine kinase 
TXK                   0.294   TXK tyrosine kinase 
TEC                   0.287   tec protein tyrosine kinase 
ITK                   0.282   IL2-inducible T-cell kinase 
CSK                   0.264   c-src tyrosine kinase 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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