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Search of human proteins with 169161145
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]
(520 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169162152 PREDICTED: hypothetical protein [Homo sapiens] 1079 0.0
gi|169161145 PREDICTED: hypothetical protein [Homo sapiens] 1079 0.0
gi|169160903 PREDICTED: hypothetical protein [Homo sapiens] 514 e-146
gi|163965366 nascent polypeptide-associated complex alpha subuni... 80 6e-15
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 69 8e-12
gi|55750053 atrophin-1 [Homo sapiens] 63 6e-10
gi|55750041 atrophin-1 [Homo sapiens] 63 6e-10
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 62 1e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 61 3e-09
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 61 3e-09
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 59 8e-09
gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo ... 59 1e-08
gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo ... 59 1e-08
gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo ... 59 1e-08
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 59 1e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 58 2e-08
gi|150170699 kinesin family member 26A [Homo sapiens] 58 2e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 58 2e-08
gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo ... 58 2e-08
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 58 2e-08
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 57 3e-08
gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo ... 57 4e-08
gi|33286436 gametogenetin [Homo sapiens] 56 7e-08
gi|118402590 myosin XV [Homo sapiens] 56 9e-08
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 56 9e-08
gi|23510413 sorting nexin 26 [Homo sapiens] 55 1e-07
gi|122937321 UNC homeobox [Homo sapiens] 55 2e-07
gi|18959210 WIRE protein [Homo sapiens] 55 2e-07
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 54 3e-07
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 54 3e-07
>gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]
Length = 520
Score = 1079 bits (2791), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MGLVWGQRKVPMTRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVAS 60
MGLVWGQRKVPMTRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVAS
Sbjct: 1 MGLVWGQRKVPMTRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVAS 60
Query: 61 GRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTR 120
GRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTR
Sbjct: 61 GRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTR 120
Query: 121 RGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHP 180
RGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHP
Sbjct: 121 RGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHP 180
Query: 181 PGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSR 240
PGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSR
Sbjct: 181 PGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSR 240
Query: 241 GRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGS 300
GRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGS
Sbjct: 241 GRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGS 300
Query: 301 RAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCAL 360
RAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCAL
Sbjct: 301 RAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCAL 360
Query: 361 GSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLR 420
GSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLR
Sbjct: 361 GSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLR 420
Query: 421 PSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDS 480
PSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDS
Sbjct: 421 PSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDS 480
Query: 481 PSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSVPP 520
PSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSVPP
Sbjct: 481 PSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSVPP 520
>gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]
Length = 520
Score = 1079 bits (2791), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MGLVWGQRKVPMTRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVAS 60
MGLVWGQRKVPMTRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVAS
Sbjct: 1 MGLVWGQRKVPMTRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVAS 60
Query: 61 GRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTR 120
GRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTR
Sbjct: 61 GRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTR 120
Query: 121 RGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHP 180
RGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHP
Sbjct: 121 RGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHP 180
Query: 181 PGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSR 240
PGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSR
Sbjct: 181 PGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSR 240
Query: 241 GRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGS 300
GRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGS
Sbjct: 241 GRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGS 300
Query: 301 RAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCAL 360
RAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCAL
Sbjct: 301 RAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCAL 360
Query: 361 GSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLR 420
GSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLR
Sbjct: 361 GSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLR 420
Query: 421 PSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDS 480
PSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDS
Sbjct: 421 PSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDS 480
Query: 481 PSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSVPP 520
PSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSVPP
Sbjct: 481 PSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSVPP 520
>gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]
Length = 426
Score = 514 bits (1323), Expect = e-146
Identities = 280/396 (70%), Positives = 289/396 (72%), Gaps = 31/396 (7%)
Query: 150 SPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPE 209
SP PP L AP R + + + G G P + + F
Sbjct: 37 SPTARAPPPILPAPQRPPTRAREWEGAAWAAGATGVGAALLALPGSRRLGRVPLTFREAS 96
Query: 210 GSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQP---PLARLLLAS 266
A P A+ + P PR R A S G+ RPAA A P LAR L S
Sbjct: 97 PGPAPGAPRARGSCGREPGPRRRR--APSSAGK----RPAAAARAAPPRQRSLARCLPRS 150
Query: 267 A-----VSLAASLAR-----------------SPPPLQPRLGSASPPRLAAPLAGSRAPS 304
S+ SL R PPPLQPRLGSASPPRLAAPLAGSRAPS
Sbjct: 151 VGSCVRPSVGPSLPRRHCRRHCRCHCRRRPLPKPPPLQPRLGSASPPRLAAPLAGSRAPS 210
Query: 305 LSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPP 364
LSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPP
Sbjct: 211 LSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPP 270
Query: 365 IPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPA 424
IPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPA
Sbjct: 271 IPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPA 330
Query: 425 TWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSP 484
TWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSP
Sbjct: 331 TWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSP 390
Query: 485 ATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSVPP 520
ATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSVPP
Sbjct: 391 ATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSVPP 426
Score = 36.6 bits (83), Expect = 0.057
Identities = 70/264 (26%), Positives = 89/264 (33%), Gaps = 51/264 (19%)
Query: 247 RPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRL------AAPLAGS 300
R A G + P A ++ + AR+PPP+ P PP AA AG+
Sbjct: 12 RTPAPGCPEVAPQPEGTDAPGPAVCSPTARAPPPILP--APQRPPTRAREWEGAAWAAGA 69
Query: 301 RAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRG--GEERRVRGRRQGC 358
+ RR R +PL + G GA R RG G E R RR
Sbjct: 70 TGVGAALLALPGSRRLGR------VPLTFREASPGPAPGAPRARGSCGREPGPRRRRAPS 123
Query: 359 ALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTC 418
+ G P A AAP R +R+ + R G V P G PR C
Sbjct: 124 SAGKRPAAAARAAPPR---QRSLARCLPRSVGSCVRPSVGPS--------LPRRHCRRHC 172
Query: 419 ---LRPSPATWQGGAPYRAIFAAGPRLSAPSA----------------EAEEVPGGHTAS 459
R P R A+ PRL+AP A AE P GH
Sbjct: 173 RCHCRRRPLPKPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLP 232
Query: 460 NPTY-----EPLSSRRTKAPSEGR 478
P E + +RR + E R
Sbjct: 233 LPRSLSRGGEVVGARRRRGGEERR 256
Score = 35.8 bits (81), Expect = 0.097
Identities = 61/226 (26%), Positives = 76/226 (33%), Gaps = 31/226 (13%)
Query: 135 PTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVP----R 190
P P+P L R SP P S P P P+ RR + P +P R
Sbjct: 180 PLPKPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSR 239
Query: 191 GQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAP-RAREEAAAGS-RGRGGAERP 248
G A +R G + P A AP RA E AA R RGG
Sbjct: 240 GGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGV 299
Query: 249 AARGSAQQPPLARLLLASAVSLAASLARSPPPLQP----RLGSASPPRLAAPLAGSRAPS 304
+ R AQ + + A + L SP Q R A+ PRL+AP A
Sbjct: 300 SPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSA------ 353
Query: 305 LSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERR 350
AE P GH P E + +RR + E R
Sbjct: 354 ----------EAEEVPGGHTASNPTY-----EPLSSRRTKAPSEGR 384
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 79.7 bits (195), Expect = 6e-15
Identities = 136/536 (25%), Positives = 186/536 (34%), Gaps = 97/536 (18%)
Query: 35 PSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFH 94
PSP+G P P+ GV + T P P V P + G AP+ AP
Sbjct: 859 PSPKGAPTPSAVTPLSPK--GVTLPPKET----PTPSVVNLPFPKEGPATPAPKQAPALS 912
Query: 95 FQPFLSLSPHQERGRSKP-----SPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLH 149
S SP + R P SP G +G TP P +W
Sbjct: 913 MT---SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP------KWAP 963
Query: 150 SPREPTPPGRLSAP----PRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHF 205
+P TPP P P+ P P + PS P G + P+G P A S
Sbjct: 964 TPPAATPPSPKGGPATPSPKGAPTPPAATPPS--PKGGPATPSPKGAPTPPAVTPPS--- 1018
Query: 206 LAPEGSVASL---------------LPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAA 250
P+GS A+ P PA P P AA +GG P+
Sbjct: 1019 --PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076
Query: 251 RGS----AQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLS 306
+G+ A PP + A+ A + + P P+ G A+PP AP + P
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP--- 1133
Query: 307 PFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIP 366
P P+ G P P+ + G +G A +PP P
Sbjct: 1134 PSPK----------GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA-ATPPSP 1182
Query: 367 AGPAA---PGRAGERRAARQWRKRGGGPGVSPR-----EGAQGEGVRGGV-TPRARGSST 417
G A P A AA +GG SP+ A +GG+ TP +G+ T
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242
Query: 418 CLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVP---GG------HTASNP-TYEPLS 467
+P + +GG A P AP+ A P GG A NP P S
Sbjct: 1243 TPAATPPSPKGGP------ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS 1296
Query: 468 SRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSR---SPYNWSPPSPSVPP 520
+ A S + +P+ PA + S GS + P + +P +PPSP P
Sbjct: 1297 PKGGPATSPPKGAPTPPAATP-----PSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347
Score = 74.3 bits (181), Expect = 2e-13
Identities = 133/560 (23%), Positives = 194/560 (34%), Gaps = 74/560 (13%)
Query: 11 PMTRRASPVFTGFCVNTSQSESFDP-SPRG--------RDGPWRHVETFPRARGVEVASG 61
P + + SP T F S + P SP+G + P T P +G
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPS 1075
Query: 62 RTRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRR 121
P P TPP+ + G +P+ AP P + P + G + +PP G
Sbjct: 1076 LKG--APTPPAATPPSPKGGPATPSPKGAP----MPPAATPPSPKGGLA--TPPHKGAPT 1127
Query: 122 GKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPP 181
+G TP P+ + P+P G L+ PP G P+A PP
Sbjct: 1128 TPAATPPSPKGGLATPPPKGAPTTP---AATPPSPKGGLATPPPKGAPTT----PAATPP 1180
Query: 182 GRGSGRV---PRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAG 238
G P+G P A S P+G +A+ P P P P + + A
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPS-----PKGGLATPSPKGAPT-TPAATPPSPKGGLAT 1234
Query: 239 SRGRGGAERPAAR------GSAQQPPLARLLLASAV--SLAASLARSP------------ 278
+G PAA G A PP +A SL LA P
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 279 ------PPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLP-LPRSL 331
P P G+ +PP A P + +P P A P+ G P LP +
Sbjct: 1295 PSPKGGPATSPPKGAPTPPA-ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 332 --SRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGG 389
S+GG + + + G A+ P GPA P G+ +
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413
Query: 390 GPGVSP--REGAQGEGVRGGVTPRARGSSTCLRPSPAT-WQGGAPYRAIFAAGPRLSAPS 446
+P REGA +G +TP A + L+ +PAT G P P L A +
Sbjct: 1414 KAPATPVTREGAATPS-KGDLTPPA-VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 447 AEAEEVPGG----HTASNPTYEPLSSRRTKAPSEGRDSPSSP--ATSTHYLDRESGLGSV 500
+ + P T+S+P P + AP+ PSSP +T R+ +
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
Query: 501 NSHPSRSPYNWSPPSPSVPP 520
++P +P +PP
Sbjct: 1532 TLLSKKTPATLAPKEALIPP 1551
Score = 59.3 bits (142), Expect = 8e-09
Identities = 105/470 (22%), Positives = 168/470 (35%), Gaps = 76/470 (16%)
Query: 35 PSPRGRDG--PWRHVETFPRARGVEVASGRT---RWTGPQPLVDTPPARRAGELCEAPQT 89
PSP+G P + T P A + G P P V TPP+ + G P+
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308
Query: 90 APGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLH 149
AP P + P + P P + T T +G + P P
Sbjct: 1309 AP----TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364
Query: 150 SPREPTPPGRLSAPPRH--GPH--PQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHF 205
S PTPP +A P H GP P S +R A P +G P P ++ +
Sbjct: 1365 SKEGPTPP---AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP--KKAPATP 1419
Query: 206 LAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLA 265
+ EG+ PS P P + ++A A S +GG P+++G P
Sbjct: 1420 VTREGAAT---PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP-------- 1468
Query: 266 SAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGL 325
++ + PP + S+SP + A A AP+L + +P+
Sbjct: 1469 ---AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
Query: 326 PLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWR 385
P+ + + + A +E + A+ P PA P
Sbjct: 1526 PIAPTATLLSKKTPATL--APKEALIPP-----AMTVPSPKKTPAIP------------- 1565
Query: 386 KRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAP 445
+P+E TP ++ +S+ +P+T++G AP P +++P
Sbjct: 1566 --------TPKEAP--------ATPSSKEASSPPAVTPSTYKG-APSPKELLIPPAVTSP 1608
Query: 446 SAEAEEVPGGHTASNPTYEPLS-------SRRTKAPSEGRDSPSSPATST 488
S + P T +P P + + PS +DSP+SPA+ T
Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVT 1658
Score = 34.3 bits (77), Expect = 0.28
Identities = 49/240 (20%), Positives = 82/240 (34%), Gaps = 41/240 (17%)
Query: 68 PQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQW 127
P P TPP+ G AP+ P SP K SP + K G
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPKGTP---------TSPPVTPSSLKDSPTSPASVTCKMGAT 1664
Query: 128 KEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGR 187
+ A + L +P + P ++AP R GP Q+ + + PP
Sbjct: 1665 VPQASKGLPAKKGPTALKEVLVAPAPESTP-IITAPTRKGP--QTKKSSATSPP------ 1715
Query: 188 VPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAER 247
+ P+ S + AP P +++++ ++G+ +
Sbjct: 1716 ------------------ICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
Query: 248 PAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSP 307
P + + + L A+A P P + +A P ++ PLA S P+L P
Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVL-----PKPESASVSAAPSPPVSLPLAPSPVPTLPP 1812
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 69.3 bits (168), Expect = 8e-12
Identities = 131/492 (26%), Positives = 181/492 (36%), Gaps = 68/492 (13%)
Query: 11 PMTRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQP 70
P R+ P +S SES PSP+ RH + P + A G R P
Sbjct: 399 PTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVS-RHASSSPESPKPAPAPGSHREISSSP 457
Query: 71 LVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSK-PSPPVSGTRRGKTGQWKE 129
T R G A + H +P + GRS+ P+ G R +T K
Sbjct: 458 ---TSKNRSHGR---AKRDKSHSH-------TPSRRMGRSRSPATAKRGRSRSRT-PTKR 503
Query: 130 GRGSHPTPEPQR-LAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRG-SGR 187
G +P+ +R +A+RW S R P GR +P R P R + GR S R
Sbjct: 504 GHSRSRSPQWRRSRSAQRWGRS-RSPQRRGRSRSPQR----PGWSRSRNTQRRGRSRSAR 558
Query: 188 VPRGQPEQQAWEQRS-SHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAE 246
R A RS S A G S P+ + +R+ P R RGR +
Sbjct: 559 RGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR 618
Query: 247 RPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLA-----APLAGSR 301
PA R S + P+ R S +RSP R S +P R P R
Sbjct: 619 TPARRRSRTRSPVRR----------RSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR 668
Query: 302 APSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRV---RGR---- 354
+ S +P RR R R+PA G R+ RG + RRG R RGR
Sbjct: 669 SRSRTP-ARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSS 727
Query: 355 --RQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRA 412
R+ + S ++P R ++R+ R SPR A+ R +
Sbjct: 728 SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLS-----SPRSKAKS---RLSLRRSL 779
Query: 413 RGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTK 472
GSS C + T P R+ + S P A++ P S + P +++K
Sbjct: 780 SGSSPCPKQKSQT----PPRRSRSGS----SQPKAKSRTPP---RRSRSSSSPPPKQKSK 828
Query: 473 APSEGRDSPSSP 484
PS S SSP
Sbjct: 829 TPSRQSHSSSSP 840
Score = 62.4 bits (150), Expect = 1e-09
Identities = 130/532 (24%), Positives = 197/532 (37%), Gaps = 62/532 (11%)
Query: 5 WGQRKVPMTR--RASPVFTGFCV--NTSQSESFDPSPRGRDGPWRHVETFPRARGVEVAS 60
WG+ + P R SP G+ NT + + RGR R T R+R A
Sbjct: 522 WGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHS-RSPATRGRSRSRTPAR 580
Query: 61 -GRTRWTGP---QPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPV 116
GR+R P + TP RR+ A + S S R RS+ PV
Sbjct: 581 RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGR---------SRSRTPARRRSRTRSPV 631
Query: 117 SGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSA--PPRHGPHPQSFR 174
R ++ + GR TP ARR R P GR + P R +S R
Sbjct: 632 RRRSRSRSPARRSGRSRSRTP------ARRGRSRSRTPARRGRSRSRTPARRSGRSRS-R 684
Query: 175 RPSAHPPGRGSGRVPR-GQPEQQAWEQRS-SHFLAPEGSVASLLPSAKPARAPRPAPRAR 232
P+ GR R PR G+ ++ +R SH P+ S S + ++ R+R
Sbjct: 685 TPARR--GRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSR 742
Query: 233 EEAAAG-SRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSP---PPLQPRLGSA 288
++ + R + R + S + +RL L ++S ++ + PP + R GS+
Sbjct: 743 SNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS 802
Query: 289 SP-PRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGE 347
P + P SR+ S SP P++ + R P P+ S G+
Sbjct: 803 QPKAKSRTPPRRSRSSS-SPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQAN 861
Query: 348 ERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSP-REGAQGEGVRG 406
E+ V +R+ C SP P R ++ K P SP R + V+
Sbjct: 862 EQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKA 921
Query: 407 GVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPL 466
++PR R S PSP+ R PR S + V L
Sbjct: 922 IISPRQRSHSGSSSPSPS--------RVTSRTTPRRSRSVSPCSNVE----------SRL 963
Query: 467 SSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSV 518
R + + S D+ P T R+S GS++ +P +PP PS+
Sbjct: 964 LPRYSHSGSSSPDTKVKPETP----PRQSHSGSISPYPKVKAQ--TPPGPSL 1009
Score = 62.4 bits (150), Expect = 1e-09
Identities = 107/415 (25%), Positives = 143/415 (34%), Gaps = 37/415 (8%)
Query: 101 LSPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRL 160
L+P +ER S+ S R GQ S + + S P +
Sbjct: 1510 LTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKT 1569
Query: 161 SAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAK 220
P R +S P R S R R + ++ + A GS +S P A
Sbjct: 1570 RTPLRQ--RSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAP 1627
Query: 221 PARAPRPAPRAREEAAAGSRGRGGAERPAA--RGSAQQPPLARLLLASAVSLAASLARSP 278
APR PR R + + S+GRG + ++ S + PP +R + S +S
Sbjct: 1628 ---APRALPR-RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSR 1683
Query: 279 PPLQPRLGSASP--PRLAAPLAGSRAPSLSPFPR-RCRRRAERSPAGHGLPLPRSLSRGG 335
P + R +SP R A SR+ S SP R R R RSP+ P P SR
Sbjct: 1684 TPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSS-PEPAEKSRSS 1742
Query: 336 EVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRG-GGPGVS 394
RRR R R+G P P G R R R+R G S
Sbjct: 1743 R----RRRSASSPRTKTTSRRG--RSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQS 1796
Query: 395 PREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPG 454
Q R VT R RG S SPA + S +
Sbjct: 1797 TSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQES-----------------SRTSSRRRR 1839
Query: 455 GHTASNPTYEPLS-SRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRSP 508
G + + PT S SR + AP + S +SPAT R + S SP
Sbjct: 1840 GRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSP 1894
Score = 53.5 bits (127), Expect = 5e-07
Identities = 139/563 (24%), Positives = 184/563 (32%), Gaps = 97/563 (17%)
Query: 28 SQSESFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAP 87
S S S R R + T R ASGR R G P + P + + +P
Sbjct: 268 SASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGR-RGEGDAPFSE--PGTTSTQRPSSP 324
Query: 88 QTAPGFHFQPFLSLSPHQ-ERGRSKPSPPVSGTRRGK-----TGQWKEGRGSHPTPEPQR 141
+TA P+ + E+ ++PSP + G T E G P P
Sbjct: 325 ETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATT 384
Query: 142 LAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHP--------------------- 180
++ ++ P E +P S P PQS S+ P
Sbjct: 385 PLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA 444
Query: 181 PGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSR 240
P GS R P + SH A S PS + R+ P A R
Sbjct: 445 PAPGSHREISSSPT----SKNRSHGRAKRDKSHSHTPSRRMGRSRSP--------ATAKR 492
Query: 241 GRGGAERPAARG--SAQQPPLARLLLASAVSLAAS---LARSPPPLQP------------ 283
GR + P RG ++ P R A + S RS P +P
Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRG 552
Query: 284 RLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPA-----GHGLPLPRSLSRGGEVV 338
R SA R + +R S S P R R R+PA RS SR
Sbjct: 553 RSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARR 612
Query: 339 GARRRRGGEERRVRGR---RQGCALGSPPIPAG------PAAPGRAGERRAARQWRKRGG 389
G R R RR R R R+ SP +G PA GR+ R AR+ R R
Sbjct: 613 GRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR 672
Query: 390 GPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAG------PRLS 443
P A+ G TP RG S P +G + R++ G P+
Sbjct: 673 TP-------ARRSGRSRSRTPARRGRSRSRTPR----RGRSRSRSLVRRGRSHSRTPQRR 721
Query: 444 APSAEAEE------VPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRE-SG 496
S + E + SN + E SR + S SP S A S L R SG
Sbjct: 722 GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSG 781
Query: 497 LGSVNSHPSRSPYNWSPPSPSVP 519
S++P S S P
Sbjct: 782 SSPCPKQKSQTPPRRSRSGSSQP 804
Score = 50.4 bits (119), Expect = 4e-06
Identities = 117/498 (23%), Positives = 169/498 (33%), Gaps = 88/498 (17%)
Query: 29 QSESFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAPQ 88
+S S P+ RGR R+R SGR+R PARR P+
Sbjct: 657 RSRSRTPARRGRS----------RSRTPARRSGRSR--------SRTPARRGRSRSRTPR 698
Query: 89 TAPGFHFQPFLSLSPH----QERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAA 144
H Q RGRS S + +T Q + S P + R+++
Sbjct: 699 RGRSRSRSLVRRGRSHSRTPQRRGRSGSSS--ERKNKSRTSQRRSRSNSSPEMKKSRISS 756
Query: 145 RRW--LHSPRE----------------PTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSG 186
RR L SPR P P + PPR S + + P R S
Sbjct: 757 RRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSR 816
Query: 187 RVPRGQPEQQA-WEQRSSHFLAPEGSVASLLPSAKPARAPRP----APRAREEAAAGSRG 241
P+Q++ R SH S +S P K PR +P+A E++
Sbjct: 817 SSSSPPPKQKSKTPSRQSH------SSSSPHPKVKSGTPPRQGSITSPQANEQSVT---- 866
Query: 242 RGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSR 301
P R + P L S S + S PP R+ S++PPR + SR
Sbjct: 867 ------PQRRSCFESSPDPEL--KSRTPSRHSCSGSSPP---RVKSSTPPRQSP----SR 911
Query: 302 APSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRG-----GEERRVRGRRQ 356
+ S P + +RS +G P P SR RR R E R+ R
Sbjct: 912 SSSPQPKVKAIISPRQRSHSGSSSPSP---SRVTSRTTPRRSRSVSPCSNVESRLLPRYS 968
Query: 357 GCALGSPPIPAGPAAPGRAGERRAARQWRKRGG----GPGVS-PREGAQGEGVRGGVTPR 411
SP P P R + + K GP +S + E + +
Sbjct: 969 HSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQS 1028
Query: 412 ARGS-STCLRPSPATWQGGAPY--RAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSS 468
GS S C +T G + + ++ G ++P ++ S+ L S
Sbjct: 1029 CPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQS 1088
Query: 469 RRTKAPSEGRDSPSSPAT 486
+ +P GR SSP T
Sbjct: 1089 KSQTSPKGGRSRSSSPVT 1106
Score = 47.4 bits (111), Expect = 3e-05
Identities = 98/405 (24%), Positives = 135/405 (33%), Gaps = 58/405 (14%)
Query: 105 QERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRW----LHSPREPTPP-GR 159
+ R RS+ SP R +T R TP +R + R R TPP R
Sbjct: 1908 RRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTR 1967
Query: 160 LSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSA 219
+ R P + R P R R ++ R+S S P A
Sbjct: 1968 RRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSR--SRTPPA 2025
Query: 220 KPARA-------PRPAPRAREEAAAGSRGRGGAERPAA--RGSAQQPPLARLLLASAVSL 270
R+ PR R+R A R R R A R + PP R AS S
Sbjct: 2026 IRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSS 2085
Query: 271 AASLARSPPPLQPRLGSASPPRL--AAPLAGSRAPSLSPFP-RRCRRRAERSPAGHG-LP 326
S + +PP + GS +PP ++ ++ PS+SP P RCR P G P
Sbjct: 2086 DRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTP 2145
Query: 327 LPRSLSRGGEVVGARRRRGGEERRV----RGRRQGCALGSPPIPAGPAAPGRAGERRAAR 382
+ GG ++ R + +R + AL I G A P
Sbjct: 2146 MSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARP---------- 2195
Query: 383 QWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRL 442
P A G R P A LR +PA R+
Sbjct: 2196 -----------PPSMSAAGLAARMSQVP-APVPLMSLRTAPAA-----------NLASRI 2232
Query: 443 SAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATS 487
A SA A + T + PT L+ RT A + + +SP T+
Sbjct: 2233 PAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNL-ASPRTA 2276
Score = 42.0 bits (97), Expect = 0.001
Identities = 134/566 (23%), Positives = 189/566 (33%), Gaps = 70/566 (12%)
Query: 8 RKVPMTRRASPVFTGFCVNT-SQSES-FDPSPRGRDGPWRHVETFPRARGVEVASGRTRW 65
R P+TRR S T + S+S + P R R + R+R A G+
Sbjct: 2009 RTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSL 2068
Query: 66 TGPQPLVDTPPARRAGELCEAPQTAPGFHFQ-----PFLSLSPHQERGRSKPSPPVSGTR 120
T P + A + T P P ++L+ + S+PS +
Sbjct: 2069 TRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLD 2128
Query: 121 RGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPG--RLSAPPRHGPHPQSFRRPSA 178
R ++ E GS TP A + P P R S P H + +
Sbjct: 2129 RCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAI 2188
Query: 179 H------PPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPR-- 230
PP + + + A S AP ++AS +P+A A + R
Sbjct: 2189 SLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTP 2248
Query: 231 ----------AREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPP 280
+R AAA + + R A SA R A AV+LA AR+P
Sbjct: 2249 AIPTAVNLADSRTPAAAAAMNLA-SPRTAVAPSAVNLADPRTPTAPAVNLAG--ARTPAA 2305
Query: 281 LQPR--LGSASPPRLAAPLAGSRAPSLSPF-----PRRCRRRAERSPAGH---GLPLPRS 330
L GS +PP A + SR P PR A + AG P S
Sbjct: 2306 LAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPAS 2365
Query: 331 LS--------RGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAP--GRAGERRA 380
L+ G + R E RV GR L P+AP R RA
Sbjct: 2366 LTSARMAPALSGANLTSPRVPLSAYE-RVSGRTSPPLLDRARSRTPPSAPSQSRMTSERA 2424
Query: 381 ARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCL--RPSPA----TWQGGAPYRA 434
+ G P S AQ + R V S CL + +P + GA
Sbjct: 2425 PSPSSRMGQAPSQSLLPPAQDQ-PRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATT 2483
Query: 435 IFAAG--------PRLSAPSAEAEEVPGGHTASNPT----YEPLSSRRTKAPSEGRDSPS 482
+AG P P ++ E P A P+ +P RR+ + S S S
Sbjct: 2484 TSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSS 2543
Query: 483 SPATSTHYLDRESGLGSVNSHPSRSP 508
S ++S+ SG S +S S P
Sbjct: 2544 SSSSSSSSSSSSSGSSSSDSEGSSLP 2569
Score = 38.9 bits (89), Expect = 0.012
Identities = 59/263 (22%), Positives = 93/263 (35%), Gaps = 41/263 (15%)
Query: 113 SPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQS 172
S P G G+ G+ +P LAA + R + S+ S
Sbjct: 2495 SVPAPGVPHSDVGEPPASTGAQ---QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSS 2551
Query: 173 FRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAR 232
S G QPE A ++ S AP+ +V + R P P P R
Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEV-ALKRVPSPTPAPKEAV-------REGRPPEPTPAKR 2603
Query: 233 EEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPR 292
+ ++ S + ++ S+ + +S+ S ++S + SP P +P G + P+
Sbjct: 2604 KRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP--GPQALPK 2661
Query: 293 LAAP-------------------LAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSR 333
A+P L SR+ S SP RR SP P PR
Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERR-----RPSPQ----PSPRDQQS 2712
Query: 334 GGEVVGARRRRGGEERRVRGRRQ 356
G+RR + G+ R +R+
Sbjct: 2713 SSSERGSRRGQRGDSRSPSHKRR 2735
Score = 38.5 bits (88), Expect = 0.015
Identities = 60/264 (22%), Positives = 82/264 (31%), Gaps = 24/264 (9%)
Query: 68 PQPLVDTPPARRAGELCEA-PQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQ 126
P V PPA + A P + S S S S S + G +
Sbjct: 2502 PHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561
Query: 127 WKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSG 186
EG PE +P+E GR PP P + R S+ S
Sbjct: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR---PPEPTPAKRKRRSSSSSSSSSSSS 2618
Query: 187 RVPRGQPEQQAWEQRSSHFLAPEGSVASLLPS-AKPARAPRPAPRAREEAAAGSRGRGGA 245
+ SS + S +S PS AKP P P + ++ G R
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGER----- 2673
Query: 246 ERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSL 305
R + + P+ L + ++S + R P P S G R S
Sbjct: 2674 -----RSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSR 2728
Query: 306 SPF---------PRRCRRRAERSP 320
SP PR R R+ RSP
Sbjct: 2729 SPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 33.5 bits (75), Expect = 0.48
Identities = 67/304 (22%), Positives = 102/304 (33%), Gaps = 54/304 (17%)
Query: 237 AGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSP---------PPLQPRLGS 287
AG P + P R AS+ + L R+P P L R GS
Sbjct: 1394 AGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGL--RDGS 1451
Query: 288 ASPPRLAAPLAGSRAPSLSPFPR---RCRRRAERSPAGHGLP-LPRSLSRG-------GE 336
+P R + L+GS +P + PR R R + SP LP PR SR +
Sbjct: 1452 GTPSRHS--LSGS-SPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNK 1508
Query: 337 VVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPR 396
+ +R R G E V + R R R G
Sbjct: 1509 CLTPQRERSGSESSVDQKTVA---------------------RTPLGQRSRSGS------ 1541
Query: 397 EGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGH 456
+Q V+ +P+ R S S A + R+ + P + + S +
Sbjct: 1542 --SQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSG 1599
Query: 457 TASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSP 516
++ +P ++ R ++ S+ P +PA SG S PS + + SP
Sbjct: 1600 SSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSP 1659
Query: 517 SVPP 520
PP
Sbjct: 1660 EHPP 1663
Score = 32.0 bits (71), Expect = 1.4
Identities = 51/238 (21%), Positives = 80/238 (33%), Gaps = 24/238 (10%)
Query: 286 GSASPPRLAAPLAGSRAPSL-SPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRR 344
GS+ P+ A A AP P+ + RSP + RG + RR
Sbjct: 148 GSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRR 207
Query: 345 GGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPRE-----GA 399
ER+ +++ S +P +R++ + RKR +P+
Sbjct: 208 ---ERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST 264
Query: 400 QGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTAS 459
+ T R+R S + G +P A G AP +E PG
Sbjct: 265 SADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEG-DAPFSE----PG----- 314
Query: 460 NPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPS 517
S++R +P PSSP +E + P RS PP+P+
Sbjct: 315 -----TTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPT 367
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 63.2 bits (152), Expect = 6e-10
Identities = 119/543 (21%), Positives = 177/543 (32%), Gaps = 84/543 (15%)
Query: 32 SFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAPQTAP 91
SF+P P + P +R + G P P P G L P
Sbjct: 182 SFEPHPSVTPTGYHAPMEPPTSRMFQAPPG-----APPPHPQLYPGGTGGVLSGPPMGPK 236
Query: 92 GFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQ-------WKEGRGSHPTPEPQRLAA 144
G + P+ + P+ P+S + G +G G G+ P+ P
Sbjct: 237 GGGAASSVG-GPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPA--- 292
Query: 145 RRWLH-SPREPTPPG------RLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQA 197
+ H +P P PP ++PP G P PS H G+G G +P G PE+
Sbjct: 293 -NFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPG-PEKGP 350
Query: 198 WEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQP 257
S H L P S A PAP R ++ S A ++ S+
Sbjct: 351 TLAPSPHSLPPASSSA-------------PAPPMRFPYSSSSSSSAAASSSSSSSSSSAS 397
Query: 258 PLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAP-SLSPFPRRCRRRA 316
P A S S PP S PP+ P S+A S P P R
Sbjct: 398 PF------PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL 451
Query: 317 ERSPAGHGLPLPRSLSRGGEV-----------VGARRRRGGEERRVRGRRQGCALGSPPI 365
+ H P P S ++++ ++++ + ++Q PP
Sbjct: 452 LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP 511
Query: 366 PAGPAAPGRAGERRAARQW---------RKRGGGPGVSP---------REGAQGEGV--- 404
P P G A + R GP P + G G V
Sbjct: 512 PGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571
Query: 405 RGGVTPRARGSSTCLRPSPATWQGGAPY-----RAIFAAGPRLSAPSAEAEEVPGGHTAS 459
+ ++GS C PSP+ GAPY + + LS A P G+ +
Sbjct: 572 SNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTA 631
Query: 460 NPTYEPLSSRRTKAPSEGRDS--PSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPS 517
+P P +R +P + + P S + G + P P + P SP+
Sbjct: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT 691
Query: 518 VPP 520
V P
Sbjct: 692 VGP 694
Score = 34.7 bits (78), Expect = 0.22
Identities = 120/560 (21%), Positives = 175/560 (31%), Gaps = 84/560 (15%)
Query: 9 KVPMTRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGP 68
+ P + +S ++S S S P P + P + +FP + V++ ++T P
Sbjct: 372 RFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP-SYPHSFPPPTSLSVSNQPPKYTQP 430
Query: 69 QPLVDT------PPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRG 122
PP G L PG PF P +S PPVS
Sbjct: 431 SLPSQAVWSQGPPPPPPYGRLLANSNAHPG----PF----PPSTGAQSTAHPPVSTHHHH 482
Query: 123 KTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAP----PRHGPHPQSFRRPSA 178
Q ++ + + Q+ ++ H P PPG P H HP + PS
Sbjct: 483 HQQQQQQQQ-----QQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS-PSL 536
Query: 179 -----HPPGRG-----------SGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAK-- 220
+PPG S P G P + SS +GS PS
Sbjct: 537 GSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSS---TSQGSYPCSHPSPSQG 593
Query: 221 PARAPRPAPRA----REEAAAGSRGRGGAERPAARGSAQQP---PLARLLLASAVSLAAS 273
P AP P P A + A PA +A P P + + A+
Sbjct: 594 PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTAT 653
Query: 274 LARSPPPLQPRLGSASPP--RLAAPLAGSR-----APSLSPFPRRCRRRAERSPAG-HGL 325
P P + +PP R +P AG +P++ P P P+G L
Sbjct: 654 PPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPL-----PPAGPSGLPSL 708
Query: 326 PLPRSLSRGGEVVGAR--RRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQ 383
P P + G + A ++ EE A P P P A + +
Sbjct: 709 PPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNK 768
Query: 384 WRKRG--------------GGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGG 429
RG G ++ + E VR RAR R +
Sbjct: 769 HLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKERE 828
Query: 430 APYRAIFAAGPRLSAPSAEAEEVPG-GHTASNPTYEPLSSRRTKAPSEGRDSPSSPATST 488
+L+ E P G P +EP S+ T P G D+P+ S
Sbjct: 829 REKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSE 888
Query: 489 HYLDRESGLGSVNSHPSRSP 508
+ G+ N HP P
Sbjct: 889 YARPHVMSPGNRN-HPFYVP 907
Score = 30.8 bits (68), Expect = 3.1
Identities = 106/446 (23%), Positives = 139/446 (31%), Gaps = 88/446 (19%)
Query: 35 PSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAPQT-APGF 93
P P G+ P P A G + P TPP R P T PG
Sbjct: 636 PPPYGKRAP------SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPG- 688
Query: 94 HFQPFLSLSPHQERGRS-------KPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARR 146
P + P G S P+ P SG T +E + TPE
Sbjct: 689 --SPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPE-------- 738
Query: 147 WLHSPREPTPPGRLSAPPRHGPHPQSFRRPS-AHPPGRGSGRVPRGQPEQQAWEQRSSHF 205
P PP R +PP P+ PS A R + + RG + + +F
Sbjct: 739 ------SPVPPARSPSPP-----PKVVDVPSHASQSARFNKHLDRG---FNSCARSDLYF 784
Query: 206 LAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLA 265
+ EGS + + + R A + E R R ER R ++ L R +
Sbjct: 785 VPLEGSKLAKKRADLVEKVRREAEQRAREEKERERER---EREKEREREKERELERSVKL 841
Query: 266 SAVSLA----ASLARSP--PPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERS 319
+ A SL P PP +P A+ P P G P+L R S
Sbjct: 842 AQEGRAPVECPSLGPVPHRPPFEPGSAVATVP----PYLGPDTPALRTLSEYARPHV-MS 896
Query: 320 PAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERR 379
P P L G + + G S PAA R E R
Sbjct: 897 PGNRNHPFYVPL-------------GAVDPGLLGYNVPALYSS-----DPAAREREREAR 938
Query: 380 AARQWRKRGGGPGVSPREGAQGEGVRG-GVTPRARGSSTCLRPSPATWQGGAPY------ 432
+ G V P E GV G G+ P R L+P P G P+
Sbjct: 939 ERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGP---PGLHPFPFHPSL 995
Query: 433 ------RAIFAAGPRLSAPSAEAEEV 452
R AAGP L + AE +
Sbjct: 996 GPLERERLALAAGPALRPDMSYAERL 1021
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 63.2 bits (152), Expect = 6e-10
Identities = 119/543 (21%), Positives = 177/543 (32%), Gaps = 84/543 (15%)
Query: 32 SFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAPQTAP 91
SF+P P + P +R + G P P P G L P
Sbjct: 182 SFEPHPSVTPTGYHAPMEPPTSRMFQAPPG-----APPPHPQLYPGGTGGVLSGPPMGPK 236
Query: 92 GFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQ-------WKEGRGSHPTPEPQRLAA 144
G + P+ + P+ P+S + G +G G G+ P+ P
Sbjct: 237 GGGAASSVG-GPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPA--- 292
Query: 145 RRWLH-SPREPTPPG------RLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQA 197
+ H +P P PP ++PP G P PS H G+G G +P G PE+
Sbjct: 293 -NFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPG-PEKGP 350
Query: 198 WEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQP 257
S H L P S A PAP R ++ S A ++ S+
Sbjct: 351 TLAPSPHSLPPASSSA-------------PAPPMRFPYSSSSSSSAAASSSSSSSSSSAS 397
Query: 258 PLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAP-SLSPFPRRCRRRA 316
P A S S PP S PP+ P S+A S P P R
Sbjct: 398 PF------PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL 451
Query: 317 ERSPAGHGLPLPRSLSRGGEV-----------VGARRRRGGEERRVRGRRQGCALGSPPI 365
+ H P P S ++++ ++++ + ++Q PP
Sbjct: 452 LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP 511
Query: 366 PAGPAAPGRAGERRAARQW---------RKRGGGPGVSP---------REGAQGEGV--- 404
P P G A + R GP P + G G V
Sbjct: 512 PGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571
Query: 405 RGGVTPRARGSSTCLRPSPATWQGGAPY-----RAIFAAGPRLSAPSAEAEEVPGGHTAS 459
+ ++GS C PSP+ GAPY + + LS A P G+ +
Sbjct: 572 SNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTA 631
Query: 460 NPTYEPLSSRRTKAPSEGRDS--PSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPS 517
+P P +R +P + + P S + G + P P + P SP+
Sbjct: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT 691
Query: 518 VPP 520
V P
Sbjct: 692 VGP 694
Score = 34.7 bits (78), Expect = 0.22
Identities = 120/560 (21%), Positives = 175/560 (31%), Gaps = 84/560 (15%)
Query: 9 KVPMTRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGP 68
+ P + +S ++S S S P P + P + +FP + V++ ++T P
Sbjct: 372 RFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP-SYPHSFPPPTSLSVSNQPPKYTQP 430
Query: 69 QPLVDT------PPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRG 122
PP G L PG PF P +S PPVS
Sbjct: 431 SLPSQAVWSQGPPPPPPYGRLLANSNAHPG----PF----PPSTGAQSTAHPPVSTHHHH 482
Query: 123 KTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAP----PRHGPHPQSFRRPSA 178
Q ++ + + Q+ ++ H P PPG P H HP + PS
Sbjct: 483 HQQQQQQQQ-----QQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS-PSL 536
Query: 179 -----HPPGRG-----------SGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAK-- 220
+PPG S P G P + SS +GS PS
Sbjct: 537 GSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSS---TSQGSYPCSHPSPSQG 593
Query: 221 PARAPRPAPRA----REEAAAGSRGRGGAERPAARGSAQQP---PLARLLLASAVSLAAS 273
P AP P P A + A PA +A P P + + A+
Sbjct: 594 PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTAT 653
Query: 274 LARSPPPLQPRLGSASPP--RLAAPLAGSR-----APSLSPFPRRCRRRAERSPAG-HGL 325
P P + +PP R +P AG +P++ P P P+G L
Sbjct: 654 PPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPL-----PPAGPSGLPSL 708
Query: 326 PLPRSLSRGGEVVGAR--RRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQ 383
P P + G + A ++ EE A P P P A + +
Sbjct: 709 PPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNK 768
Query: 384 WRKRG--------------GGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGG 429
RG G ++ + E VR RAR R +
Sbjct: 769 HLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKERE 828
Query: 430 APYRAIFAAGPRLSAPSAEAEEVPG-GHTASNPTYEPLSSRRTKAPSEGRDSPSSPATST 488
+L+ E P G P +EP S+ T P G D+P+ S
Sbjct: 829 REKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSE 888
Query: 489 HYLDRESGLGSVNSHPSRSP 508
+ G+ N HP P
Sbjct: 889 YARPHVMSPGNRN-HPFYVP 907
Score = 30.8 bits (68), Expect = 3.1
Identities = 106/446 (23%), Positives = 139/446 (31%), Gaps = 88/446 (19%)
Query: 35 PSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAPQT-APGF 93
P P G+ P P A G + P TPP R P T PG
Sbjct: 636 PPPYGKRAP------SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPG- 688
Query: 94 HFQPFLSLSPHQERGRS-------KPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARR 146
P + P G S P+ P SG T +E + TPE
Sbjct: 689 --SPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPE-------- 738
Query: 147 WLHSPREPTPPGRLSAPPRHGPHPQSFRRPS-AHPPGRGSGRVPRGQPEQQAWEQRSSHF 205
P PP R +PP P+ PS A R + + RG + + +F
Sbjct: 739 ------SPVPPARSPSPP-----PKVVDVPSHASQSARFNKHLDRG---FNSCARSDLYF 784
Query: 206 LAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLA 265
+ EGS + + + R A + E R R ER R ++ L R +
Sbjct: 785 VPLEGSKLAKKRADLVEKVRREAEQRAREEKERERER---EREKEREREKERELERSVKL 841
Query: 266 SAVSLA----ASLARSP--PPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERS 319
+ A SL P PP +P A+ P P G P+L R S
Sbjct: 842 AQEGRAPVECPSLGPVPHRPPFEPGSAVATVP----PYLGPDTPALRTLSEYARPHV-MS 896
Query: 320 PAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERR 379
P P L G + + G S PAA R E R
Sbjct: 897 PGNRNHPFYVPL-------------GAVDPGLLGYNVPALYSS-----DPAAREREREAR 938
Query: 380 AARQWRKRGGGPGVSPREGAQGEGVRG-GVTPRARGSSTCLRPSPATWQGGAPY------ 432
+ G V P E GV G G+ P R L+P P G P+
Sbjct: 939 ERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGP---PGLHPFPFHPSL 995
Query: 433 ------RAIFAAGPRLSAPSAEAEEV 452
R AAGP L + AE +
Sbjct: 996 GPLERERLALAAGPALRPDMSYAERL 1021
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 62.4 bits (150), Expect = 1e-09
Identities = 125/556 (22%), Positives = 185/556 (33%), Gaps = 99/556 (17%)
Query: 31 ESFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVD----TPPARRAGELCEA 86
+S PSPR R P R +R RT+ P P + TP +
Sbjct: 176 KSRSPSPRRRSSPVRRERKRSHSRSPR---HRTKSRSPSPAPEKKEKTPELPEPSVKVKE 232
Query: 87 PQTAPGFHFQPFLSL-SPHQERGRSKPSP--------------PVSGTRRGKTGQWKEGR 131
P L + P +PSP P S +R + +
Sbjct: 233 PSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRS 292
Query: 132 GSHPTPE-----------PQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRR----- 175
SH P P+R + R SPR TPP R+ PPRH RR
Sbjct: 293 PSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSS 352
Query: 176 -----PSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGS----------VASLLPSAK 220
S+ S P+ P++ + R + L+P S A+ P +
Sbjct: 353 ASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR 412
Query: 221 PARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQ------PPLARLLLASAVSLAASL 274
+ P+ + R R+ + S GR + +G+ ++ P ++ L+ +
Sbjct: 413 HSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGK 472
Query: 275 ARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCR-------RRAERSPAGHGLPL 327
+ +Q R + ++ +GS + S P+R RR SP+ P
Sbjct: 473 MAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPS 532
Query: 328 PRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKR 387
PR + G RRRR R RR P PA P RR R
Sbjct: 533 PRKRQKETSPRG-RRRRSPSPPPTRRRRS-------PSPAPPP------RRRRTPTPPPR 578
Query: 388 GGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGP---RLSA 444
P PR R +PR R SP+ P R + P R ++
Sbjct: 579 RRTPSPPPR--------RRSPSPRRYSPPIQRRYSPSP----PPKRRTASPPPPPKRRAS 626
Query: 445 PSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHP 504
PS + P++ RR+ + S SSP+ ST RE+ N
Sbjct: 627 PSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRST----REARSPQPNKRH 682
Query: 505 SRSPYNWSPPSPSVPP 520
S SP +P + S PP
Sbjct: 683 SPSPRPRAPQTSSSPP 698
Score = 62.4 bits (150), Expect = 1e-09
Identities = 66/232 (28%), Positives = 95/232 (40%), Gaps = 15/232 (6%)
Query: 102 SPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAA----RRWLHSPREPTPP 157
SP R RS PSPP + RR + R PTP P+R RR SPR +PP
Sbjct: 541 SPRGRRRRS-PSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPP 599
Query: 158 GRL----SAPPRH---GPHPQSFRRPSAHPPG--RGSGRVPRGQPEQQAWEQRSSHFLAP 208
+ S PP+ P P RR S PP R S P Q ++RS +
Sbjct: 600 IQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK 659
Query: 209 EGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAV 268
+S S + AR+P+P R + + P RG A P R + +
Sbjct: 660 HRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRG-ASSSPQRRQSPSPST 718
Query: 269 SLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSP 320
++R+P P + + ++ P+ ++ SR+ S SP P + A SP
Sbjct: 719 RPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSP 770
Score = 60.1 bits (144), Expect = 5e-09
Identities = 106/440 (24%), Positives = 151/440 (34%), Gaps = 67/440 (15%)
Query: 13 TRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVASGRT-------RW 65
TRR SP + S P P+ R P R V V+ GRT +
Sbjct: 385 TRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKG 444
Query: 66 TGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGT------ 119
T + P R EL E+ + G Q R +++ S SG+
Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504
Query: 120 --------RRGKTGQWKE---GRGSHPTPEPQRLAARRWLHSPREPTPP------GRLSA 162
+ G+ G+ + R + P+P ++ R P+PP A
Sbjct: 505 ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPA 564
Query: 163 PP---RHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSA 219
PP R P P RR + PP R S R P Q +R S P+ AS P
Sbjct: 565 PPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQ---RRYSPSPPPKRRTASPPPPP 621
Query: 220 KPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLA-RLLLASAVSLAASLARSP 278
K +P P P+ R + + R P + + P L+ + S+ S + ARSP
Sbjct: 622 KRRASPSPPPKRRVSHSPPPKQRSS---PVTK--RRSPSLSSKHRKGSSPSRSTREARSP 676
Query: 279 PPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLP-----RSLSR 333
P + S P RAP S P RR A SP P P R +SR
Sbjct: 677 QPNKRHSPSPRP----------RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726
Query: 334 GGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAG---PAAPGRAGERRAARQW------ 384
E ++ + VR ++ P PA PA P + + W
Sbjct: 727 TPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPV 786
Query: 385 -RKRGGGPGVSPREGAQGEG 403
+ + P SP + EG
Sbjct: 787 KKAKSPTPSPSPPRNSDQEG 806
Score = 42.4 bits (98), Expect = 0.001
Identities = 101/417 (24%), Positives = 136/417 (32%), Gaps = 68/417 (16%)
Query: 128 KEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGR 187
+E S E R RR SP P R S+P R + R S P R R
Sbjct: 157 EEKESSREKRERSRSPRRRKSRSPS----PRRRSSPVRR----ERKRSHSRSPRHRTKSR 208
Query: 188 VPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARA---------PRPAPRARE---EA 235
P PE++ PE SV PS + A + P P P +E E
Sbjct: 209 SPSPAPEKKEKTPE-----LPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEK 263
Query: 236 AAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAA 295
+ RP +R ++ S + + +RSP +PR S R
Sbjct: 264 NSKKEKEKEKTRPRSRSRSK-------------SRSRTRSRSPSHTRPRRRHRSRSR--- 307
Query: 296 PLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRR 355
S +P P PRR R+P P PR R V RRR
Sbjct: 308 ----SYSPRRRPSPRRRPSPRRRTPPRRMPPPPRH-RRSRSPVRRRRRSSASLSGSSSSS 362
Query: 356 QGCALGSPP--IPAGPAAPGRAGER----RAARQWRKRGGGPGVSPREGAQGEGVRGGVT 409
SPP P ++P R R + + R R P P + R T
Sbjct: 363 SSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK------TRHSPT 416
Query: 410 P----RARGSSTCLRP----SPATWQGGAPYRAIFAAGPR-LSAPSAEAEEVPGGHTASN 460
P R R S + P T G R + P+ +E+EE GG A+
Sbjct: 417 PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAA 476
Query: 461 PTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRES-GLGSVNSHPSRSPYNWSPPSP 516
+ + R + DS SS ++ R G V SP + PSP
Sbjct: 477 DSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 60.8 bits (146), Expect = 3e-09
Identities = 98/365 (26%), Positives = 129/365 (35%), Gaps = 45/365 (12%)
Query: 174 RRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSV-----ASLLPSAKPARAPRPA 228
R P+A PG + R P + L G+V A A P A
Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
Query: 229 PRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSL--AASLARSPPPLQPRLG 286
PRA +AG+ R A RP A G ++ P A+ VS AS P PL +
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134
Query: 287 SASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLP----RSLSRGGEVVGARR 342
S A + AP S RR + S G P P RS + G EV R
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARR--DTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192
Query: 343 RRGGEER-RVRGRRQGCALGS-----PPIPAGPAAPGRAGE-RRAARQWRKRGGGPGVSP 395
R G R+ + S P PA P G +R A + P SP
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 396 REGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGG 455
G RG TPRA + +P P Q P P+++ P +A G
Sbjct: 253 --ARSGPSARG--TPRAPAHPS--QPKPKGLQALRP--------PQVTPPRKDAAPAL-G 297
Query: 456 HTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPS 515
+S+P P S P D+ ++P +T S P +P +PPS
Sbjct: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPLPAT----------LPPSPPLATPLPLAPPS 347
Query: 516 PSVPP 520
PS PP
Sbjct: 348 PSAPP 352
Score = 53.1 bits (126), Expect = 6e-07
Identities = 105/458 (22%), Positives = 139/458 (30%), Gaps = 53/458 (11%)
Query: 70 PLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKE 129
P + +PP + +P P P L+L P Q SPP+S
Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL---------- 645
Query: 130 GRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAP---PRHGPHPQSFRRPSAHPPGRGSG 186
+ P+P+ A L +P P P + AP P P S PS PP +
Sbjct: 646 ---ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
Query: 187 --RVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGG 244
+VP P P A+ P A P A P A+
Sbjct: 703 PLQVPPSPPASP-----------PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA 751
Query: 245 AERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPS 304
P PPL A + LA+ PP P L A+PP A P + P
Sbjct: 752 TPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL--ATPPLQALPSPPASFPG 809
Query: 305 LSPFPRRCR----------RRAERSPAGHGLPLPRSLSRGGEVVGARR-RRGGEERRVRG 353
+PF +A A L +P S + RR G + V G
Sbjct: 810 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 869
Query: 354 RRQGCAL--GSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQG--EGVRGGVT 409
R AL G PP P+ + +G A S E +G G GG
Sbjct: 870 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGH------SSSATSTPEELRGYDSGPEGGAA 923
Query: 410 PRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSR 469
+ PA W G F P P A PG YE
Sbjct: 924 ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG-PGSADGLCTIYETEGPE 982
Query: 470 RTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRS 507
D SP TS +G G+ + P ++
Sbjct: 983 SATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 1020
Score = 47.0 bits (110), Expect = 4e-05
Identities = 81/300 (27%), Positives = 108/300 (36%), Gaps = 68/300 (22%)
Query: 75 PPARRAGELCEA--PQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGRG 132
P A RAG + A P++AP P + G S +P GRG
Sbjct: 57 PLAERAGGIGGATIPESAP--------RAGPTRSAGTSSRNPASRPPA--------SGRG 100
Query: 133 SHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPP-GRGSGRVPRG 191
P SP + PGR S R GP Q R SA RG
Sbjct: 101 ERAPPAKNT--------SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK 152
Query: 192 QPEQQAWEQRSSHFLAPEGSVASLLPSAKPARA----PRPAPRA---------REEAAAG 238
+ A +R + P ++ ++ A PRPAP A R+ ++
Sbjct: 153 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 212
Query: 239 SRGRGGAERPAAR-----GSAQQPPLARLLLASAVSLAASLARSPP-----------PLQ 282
S PAAR G Q P +R L +SA L +S ARS P P Q
Sbjct: 213 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL-SSPARSGPSARGTPRAPAHPSQ 271
Query: 283 PR---LGSASPPRL------AAPLAG--SRAPSLSPFPRRCRRRAERSPAGHGLPLPRSL 331
P+ L + PP++ AAP G S +P +P P + R P PLP +L
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATL 331
Score = 45.1 bits (105), Expect = 2e-04
Identities = 59/245 (24%), Positives = 81/245 (33%), Gaps = 48/245 (19%)
Query: 68 PQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQW 127
P PL PP + PQ P P L PSPP+S
Sbjct: 573 PSPLTTPPPETPSSIATPPPQAPPALASPPLQGL----------PSPPLSPL-------- 614
Query: 128 KEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGR 187
+ P P+ A L +P P+PP P P PQ+ + H +
Sbjct: 615 -----ATPPPQAPPXLALPPLQAP--PSPPASPPLSPLATPSPQAPNALAVHLL-QAPFS 666
Query: 188 VPRGQPEQQAWEQRSSHFLAPEGSVASLLP---SAKPARAPRPAPRAREEAAAGSRGRGG 244
P P Q + +S ++P + S P +A P + P P+P A + +
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-PSPPASPPMSPSATPPPQ 725
Query: 245 AERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPS 304
A P A Q PP SPP P SA+PP PL +
Sbjct: 726 APPPLAAPPLQVPP------------------SPPASPPMSPSATPPPRVPPLLAAPPLQ 767
Query: 305 LSPFP 309
+ P P
Sbjct: 768 VPPSP 772
Score = 43.5 bits (101), Expect = 5e-04
Identities = 126/511 (24%), Positives = 173/511 (33%), Gaps = 83/511 (16%)
Query: 59 ASGRTRWTGPQPL------VDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKP 112
ASG TR P PL + G+ EAP+ + +LS R S P
Sbjct: 120 ASGTTR---PGPLGQKGLRISAEETVARGKATEAPKRS---------ALSAGARRDTSGP 167
Query: 113 SPPV-----------SGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLS 161
+P +GT G R PT P++ + HS EP+P R
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
Query: 162 APPRHGPHPQSFR--RPSAHP---PGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLL 216
G + R SA P P R SG RG P A + P+G A
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPAR-SGPSARGTPRAPAHPSQPK----PKGLQALRP 282
Query: 217 PSAKPAR---APRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLL-----LASAV 268
P P R AP P + A S G RP PL L LA+ +
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPS-GTKARPVPPPDNAATPLPATLPPSPPLATPL 341
Query: 269 SLAASLARSPPPLQPRLG-SASPPRLAAPLAGS----RAPSLSPFPRRCRRRAERSPAGH 323
LA +PP LQ A+PP A P + PSL P + SP+
Sbjct: 342 PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401
Query: 324 GLPLPRSLS--RGGEVVGARRRRGGEERRVRGRRQ-GCALGSPPIPAG---PAAPGRAGE 377
P P +LS + +G+ + RQ +L SP PA + P +A
Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461
Query: 378 RRAARQWRKRGGGPGVSPREG------AQGEGVRGGVTPRARGSSTCLRPSPATWQGGAP 431
A + P VSP Q +P+A SS + P T AP
Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS-LIMPPLETQSSLAP 520
Query: 432 YRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAP--SEGRDSPSSPATSTH 489
P L P A P + P+ P + AP + ++P PA
Sbjct: 521 --------PSLQTPPASLTTPP---LENLPSLAPPPLQTASAPLTTPHLETPPCPAP--- 566
Query: 490 YLDRESGLGSVNSHPSRSPYNWSPPSPSVPP 520
++ + + P +P + + P P PP
Sbjct: 567 -CPLQAPPSPLTTPPPETPSSIATPPPQAPP 596
Score = 37.7 bits (86), Expect = 0.026
Identities = 123/548 (22%), Positives = 175/548 (31%), Gaps = 117/548 (21%)
Query: 12 MTRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPL 71
+ R AS + S PS RG H P+ +G++ +P
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-PKPKGLQAL---------RPP 283
Query: 72 VDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGR 131
TPP + A AP P P + SP + R P P + T T
Sbjct: 284 QVTPPRKDA-----APALGP-LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL 337
Query: 132 GSH---PTPEPQRLAARRWLHSPREPTP---PGRLSAPPRHGPH----------PQSFRR 175
+ P P + + L SP P P ++ PP P P S
Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397
Query: 176 PSAHPPGRG------SGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAP 229
PS P G P QA S ++P + ASL ++PA P +P
Sbjct: 398 PSLQAPPSPLALSSLQATTSLGSPTLQA--THSFLTMSPRQTQASLTSPSRPASTPPDSP 455
Query: 230 RAREEAAA-GSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSP------PPLQ 282
+ + S + PA S PL L + SLA+ ++P PPL+
Sbjct: 456 PLQAPLSLPASPPLQTSLSPAV--SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE 513
Query: 283 PRLGSASPPRLAAPLAG------SRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGE 336
+ S +PP L P A PSL+P P + +P P P
Sbjct: 514 TQ-SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP------ 566
Query: 337 VVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPR 396
C L +PP P P P +P
Sbjct: 567 ---------------------CPLQAPPSPLTTPPPETPSSIATP---------PPQAPP 596
Query: 397 EGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGH 456
A +P +G PSP P A P L+ P +A P
Sbjct: 597 ALA---------SPPLQGL-----PSPPLSPLATPPPQ---APPXLALPPLQAPPSP--- 636
Query: 457 TASNPTYEPLSSRRTKAPSEGR----DSPSSPATSTHYLDRESGLGSVNSHPSRSPYNWS 512
++P PL++ +AP+ +P SP S S S PS +P + +
Sbjct: 637 -PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 695
Query: 513 PPSPSVPP 520
PPS + PP
Sbjct: 696 PPSLAAPP 703
Score = 33.1 bits (74), Expect = 0.63
Identities = 55/220 (25%), Positives = 76/220 (34%), Gaps = 25/220 (11%)
Query: 70 PLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKT---GQ 126
PL+ PP+ A +AP+ P P S+S + P PP +R + G
Sbjct: 838 PLLQVPPSPPASPTLQAPRRPPTPG--PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895
Query: 127 WKEGRGSHPTPEPQRLAARRWLHSPR-----EPTPPGRLSAPPRHGPHPQSFRRPSAHPP 181
G S T P+ L R + P P P L+A HP ++ R A P
Sbjct: 896 DLAGHSSSATSTPEEL--RGYDSGPEGGAAASPPPDAELAAC-----HPAAWSRGPAPPL 948
Query: 182 G-RGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSR 240
RG+ P P E A A P P+P AA
Sbjct: 949 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 1008
Query: 241 GRGGAERPAARGSAQQPPLARL-------LLASAVSLAAS 273
G G + R + + PL L LL+ + LAA+
Sbjct: 1009 GAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 1048
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 60.8 bits (146), Expect = 3e-09
Identities = 94/360 (26%), Positives = 127/360 (35%), Gaps = 47/360 (13%)
Query: 174 RRPSAHPPGRGSGRVPRGQPEQQAW-----EQRSSHFLAPEGSVASLLPSAKPARAPR-P 227
+RP PGR S R G + + RS L+P+ ++ + R P
Sbjct: 241 KRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSP 300
Query: 228 APRAREEAAAGSRGRGGAERPAARG----SAQQPPLARLLLASAVSLAASLARSPPPLQP 283
+P + R G +R A G SA PP + V A+ A PP +
Sbjct: 301 SPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPAR- 359
Query: 284 RLGSASPPRLAAPLA---GSRAPSLSPFPRRCRRRAERS------PAGHGLPLPRSLSRG 334
G SP +AP + G RA + RR RRR RS P G PR
Sbjct: 360 --GKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPR 417
Query: 335 GEVVGARRRRGGEERRVRGRRQGCALGSP-PIPAGPAAPGRAGERRAARQWRKRGGGPGV 393
G R R + G G+P P P + G G + A++ R
Sbjct: 418 GSSRSLSRARSSSD-------SGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAST 470
Query: 394 SPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVP 453
SP GA G RGG P + SS P P +W + P S S AE+ P
Sbjct: 471 SPSPGAHGR--RGG--PEGKSSSRSPGPHPRSWSS--------SRSPSKSR-SRSAEKRP 517
Query: 454 GGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRSPYNWSP 513
+ S +PLS + EGR + S A +T R + SP P
Sbjct: 518 HSPSRSPSPKKPLSRDK---DGEGR-ARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEP 573
Score = 52.8 bits (125), Expect = 8e-07
Identities = 72/259 (27%), Positives = 99/259 (38%), Gaps = 37/259 (14%)
Query: 286 GSASPPRLAAPLAGSRAPS-LSPFPR-RCRRRAERSPAGHGLPLPRSLSRGGEVVGARRR 343
GS+ P L++ + SR+PS LSP R R+ + +G P P GG G+ +R
Sbjct: 258 GSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSP----SGGSGWGSPQR 313
Query: 344 RGGEERR--VRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPRE--GA 399
GG +R G R G A P P+ P +P + AA G SPR +
Sbjct: 314 NGGSGQRSGAHGGRPGSAHSPPDKPSSP-SPRVRDKAAAAAPTPPARGKESPSPRSAPSS 372
Query: 400 QGEGVR--GGV------------------TPRARGSSTCLRPSPATWQGGAPYRAIFAAG 439
QG G R GG PR RG RP PA +G + R++ A
Sbjct: 373 QGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRR---RPRPAPPRGSS--RSLSRAR 427
Query: 440 PRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGS 499
+ S PG S + R + P R + +SP+ H S
Sbjct: 428 SSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKS 487
Query: 500 VNSHPSRSPYNWSPP-SPS 517
+ P P +WS SPS
Sbjct: 488 SSRSPGPHPRSWSSSRSPS 506
Score = 47.8 bits (112), Expect = 2e-05
Identities = 83/284 (29%), Positives = 106/284 (37%), Gaps = 56/284 (19%)
Query: 100 SLSPHQERGRSKPSPPV---SGTRRGKTGQWKEGRGSHPTPEPQRLAAR-RWLHSPREPT 155
S SP G SP SG R G G + G P +P + R R + PT
Sbjct: 297 SRSPSPSGGSGWGSPQRNGGSGQRSGAHGG-RPGSAHSPPDKPSSPSPRVRDKAAAAAPT 355
Query: 156 PP--GRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVA 213
PP G+ S PR P Q GRG GR G ++ +R + +
Sbjct: 356 PPARGKESPSPRSAPSSQ----------GRG-GRAAGGAGRRRRRRRRRRRSRSSASA-- 402
Query: 214 SLLPSAKPARAPRPAP---------RAREEAAAGSRGRG----GAERPAARG-------S 253
P + R PRPAP RAR + +GS GRG G E + RG +
Sbjct: 403 ---PRRRGRRRPRPAPPRGSSRSLSRARSSSDSGS-GRGAPGPGPEPGSERGHGGHGKRA 458
Query: 254 AQQPPLARLLLASAVSLAASLARSPPPLQPRLG--SASPPRLAAPLAGSRAPSLSPFPRR 311
++PP AR AS + SP R G S R P S + S SP R
Sbjct: 459 KERPPRAR---------PASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSR 509
Query: 312 CRRRAERSPAGHGLPLPRS-LSRGGEVVGARRRRGGEERRVRGR 354
R +R + P P+ LSR + G R E R R R
Sbjct: 510 SRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRR 553
Score = 47.8 bits (112), Expect = 2e-05
Identities = 60/216 (27%), Positives = 81/216 (37%), Gaps = 18/216 (8%)
Query: 107 RGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRH 166
RG+ PSP + + +G+ G+ G G +R +R +PR APPR
Sbjct: 359 RGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRG 418
Query: 167 GPHPQSFRRPSAHPPGRGSGR-VPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPA-RA 224
S R S+ GSGR P PE + H P A+PA +
Sbjct: 419 SSRSLSRARSSS---DSGSGRGAPGPGPEPGSERGHGGH----GKRAKERPPRARPASTS 471
Query: 225 PRPAPRAREEAAAG-SRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQP 283
P P R G S R P + S++ P +R SA S +RSP P +P
Sbjct: 472 PSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSR--SRSAEKRPHSPSRSPSPKKP 529
Query: 284 RL------GSASPPRLAAPLAGSRAPSLSPFPRRCR 313
G A A A R+ S SP +R R
Sbjct: 530 LSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRR 565
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 59.3 bits (142), Expect = 8e-09
Identities = 128/492 (26%), Positives = 169/492 (34%), Gaps = 99/492 (20%)
Query: 35 PSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFH 94
P P+G GP H+ G + G GPQ PP + G L PQ PG
Sbjct: 693 PGPQGSSGPQGHM-------GPQGPPGPQGHIGPQG----PPGPQ-GHL--GPQGPPGTQ 738
Query: 95 FQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPRE- 153
P RG P P G + G Q +G S + PRE
Sbjct: 739 GMQ----GPPGPRGMQGPPHP-HGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPREN 793
Query: 154 --PTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGS 211
P P G + P PQ R P HPPG G P+ Q E R P+GS
Sbjct: 794 QGPAPQGMIMGHP-----PQEMRGP--HPPGGLLGHGPQEMRGPQ--EIRGMQGPPPQGS 844
Query: 212 VASLLPSAKPARAPRPAPRAREEAAAGSRG---RGGAERPAARGSAQQPPLARLLLASAV 268
+L + R P P ++++ GS G +GG + P Q P AR S
Sbjct: 845 ---MLGPPQELRGP-PGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNP--ARGPHPSQG 898
Query: 269 SLAASLARSP-------PPLQPRLGSASPPRLAAPL----AGSRAPSLSPFPRRCRRRAE 317
+ ++P P S PP L L A R P L+P + +
Sbjct: 899 PIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGD 958
Query: 318 -RSPAGHGL-PLP--RSLSRGGEVVGARRR--RGGEERRVRGRRQGCALGSPPIPAGPAA 371
R P H + P+ R GG G R RGG++ R R+G P P +
Sbjct: 959 SRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRG---PHPDFPDDFSR 1015
Query: 372 P-----------------GRAGERRAARQWRKRGGGPGVSP--REGAQGEGVRGGVTPRA 412
P GR G +WR+ G GP P RE ++G+G
Sbjct: 1016 PDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDG--------- 1066
Query: 413 RGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTK 472
RG++ R P W+G P F P P + P +E +
Sbjct: 1067 RGAA---RGPPGAWEGRRPGDERFPRDP--EDPRFRGRREESFRRGAPPRHE------GR 1115
Query: 473 APSEGRDSPSSP 484
AP GRD P
Sbjct: 1116 APPRGRDGFPGP 1127
>gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo
sapiens]
Length = 355
Score = 58.5 bits (140), Expect = 1e-08
Identities = 85/308 (27%), Positives = 106/308 (34%), Gaps = 44/308 (14%)
Query: 97 PFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREP-- 154
PF P + + K G+ G G + P P P SPR P
Sbjct: 46 PFKKSKPFLPQSKQKADTETIGSSGGSRGPSPAHPWTTPQPGPPHQPGFNPASSPRLPLP 105
Query: 155 ---TPPGRLSAPPRHGP-------HPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSH 204
P SAP GP + ++ + + S RVPR + Q
Sbjct: 106 ADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGLTKYNSAHSSSRVPRPRLPSQRRGASCGL 165
Query: 205 FLAPEGSVASLLPSAKPARA-----------PRPAPRAREEAAAGS-RGRGGAERPAARG 252
PE A + ARA P P P AG G G R A G
Sbjct: 166 GPGPESRAARQGLGGRSARARTRRGPHRTRRPEPGPHHTGARQAGPLPGTRGRTRAAGTG 225
Query: 253 SAQQPPLARLLLASAVSLAAS---LARSPPP----LQPRLGSASPPRLAAPLAGSRAPSL 305
SA + P AR L +V+ AA+ L SPP PR A PP P + +PS
Sbjct: 226 SAARGP-ARHLRGGSVAAAAAARCLGLSPPGRSRLFSPRSSLARPPLRFPPARPALSPSA 284
Query: 306 SPFPRRCRRRAERS--PAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSP 363
RRCR +S PA H + R + +R R G R RR G G
Sbjct: 285 R---RRCRVNWNQSSRPASH------NAQRAARHIPSRPRASGLRARA-ARRPGLDPGPA 334
Query: 364 PIPAGPAA 371
P P PAA
Sbjct: 335 PYPLTPAA 342
Score = 39.3 bits (90), Expect = 0.009
Identities = 65/226 (28%), Positives = 76/226 (33%), Gaps = 44/226 (19%)
Query: 103 PHQERGRS---KPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGR 159
P Q RG S P P R+G G+ R RR H R P P
Sbjct: 155 PSQRRGASCGLGPGPESRAARQGLGGRSARAR------------TRRGPHRTRRPEPGPH 202
Query: 160 LSAPPRHGPHPQSFRRPSAHPPG---RGSGRVPRGQPEQQAWEQRS--------SHFLAP 208
+ + GP P + R A G RG R RG A R S +P
Sbjct: 203 HTGARQAGPLPGTRGRTRAAGTGSAARGPARHLRGGSVAAAAAARCLGLSPPGRSRLFSP 262
Query: 209 EGSVAS---LLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLA 265
S+A P A+PA +P R R SR + AAR +P
Sbjct: 263 RSSLARPPLRFPPARPALSPSARRRCRVNWNQSSRPASHNAQRAARHIPSRP-------- 314
Query: 266 SAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRR 311
A L A AR P L P G A P A L P SP P R
Sbjct: 315 RASGLRARAARR-PGLDP--GPAPYPLTPAAL----RPGTSPHPGR 353
Score = 37.4 bits (85), Expect = 0.033
Identities = 73/320 (22%), Positives = 100/320 (31%), Gaps = 77/320 (24%)
Query: 207 APEGSVASLLPSAKPARAPRP-APRAREEAAAGSRGRGGAER---PAARGSAQQPPLARL 262
+P G SL P + +P P+++++A + G G R PA + QP
Sbjct: 34 SPPGEAYSL--PELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSPAHPWTTPQPG---- 87
Query: 263 LLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAG 322
PP QP AS PRL P A S + + PR G
Sbjct: 88 ----------------PPHQPGFNPASSPRLPLP-ADSEPDAYTSAPR-----------G 119
Query: 323 HGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAAR 382
G P + G R GG + + P +P+ +RR A
Sbjct: 120 SG---PTYCAGAGN-----SRAGGGLTKYNSAHSSSRVPRPRLPS---------QRRGA- 161
Query: 383 QWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIF--AAGP 440
G GPG R QG G R RG RP P GA G
Sbjct: 162 ---SCGLGPGPESRAARQGLGGRSARARTRRGPHRTRRPEPGPHHTGARQAGPLPGTRGR 218
Query: 441 RLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSV 500
+A + A P H ++R GR SP +S
Sbjct: 219 TRAAGTGSAARGPARHLRGGSVAAAAAARCLGLSPPGRSRLFSPRSSL------------ 266
Query: 501 NSHPSRSPYNWSPPSPSVPP 520
+R P + P P++ P
Sbjct: 267 ----ARPPLRFPPARPALSP 282
>gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo
sapiens]
Length = 355
Score = 58.5 bits (140), Expect = 1e-08
Identities = 85/308 (27%), Positives = 106/308 (34%), Gaps = 44/308 (14%)
Query: 97 PFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREP-- 154
PF P + + K G+ G G + P P P SPR P
Sbjct: 46 PFKKSKPFLPQSKQKADTETIGSSGGSRGPSPAHPWTTPQPGPPHQPGFNPASSPRLPLP 105
Query: 155 ---TPPGRLSAPPRHGP-------HPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSH 204
P SAP GP + ++ + + S RVPR + Q
Sbjct: 106 ADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGLTKYNSAHSSSRVPRPRLPSQRRGASCGL 165
Query: 205 FLAPEGSVASLLPSAKPARA-----------PRPAPRAREEAAAGS-RGRGGAERPAARG 252
PE A + ARA P P P AG G G R A G
Sbjct: 166 GPGPESRAARQGLGGRSARARTRRGPHRTRRPEPGPHHTGARQAGPLPGTRGRTRAAGTG 225
Query: 253 SAQQPPLARLLLASAVSLAAS---LARSPPP----LQPRLGSASPPRLAAPLAGSRAPSL 305
SA + P AR L +V+ AA+ L SPP PR A PP P + +PS
Sbjct: 226 SAARGP-ARHLRGGSVAAAAAARCLGLSPPGRSRLFSPRSSLARPPLRFPPARPALSPSA 284
Query: 306 SPFPRRCRRRAERS--PAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSP 363
RRCR +S PA H + R + +R R G R RR G G
Sbjct: 285 R---RRCRVNWNQSSRPASH------NAQRAARHIPSRPRASGLRARA-ARRPGLDPGPA 334
Query: 364 PIPAGPAA 371
P P PAA
Sbjct: 335 PYPLTPAA 342
Score = 39.3 bits (90), Expect = 0.009
Identities = 65/226 (28%), Positives = 76/226 (33%), Gaps = 44/226 (19%)
Query: 103 PHQERGRS---KPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGR 159
P Q RG S P P R+G G+ R RR H R P P
Sbjct: 155 PSQRRGASCGLGPGPESRAARQGLGGRSARAR------------TRRGPHRTRRPEPGPH 202
Query: 160 LSAPPRHGPHPQSFRRPSAHPPG---RGSGRVPRGQPEQQAWEQRS--------SHFLAP 208
+ + GP P + R A G RG R RG A R S +P
Sbjct: 203 HTGARQAGPLPGTRGRTRAAGTGSAARGPARHLRGGSVAAAAAARCLGLSPPGRSRLFSP 262
Query: 209 EGSVAS---LLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLA 265
S+A P A+PA +P R R SR + AAR +P
Sbjct: 263 RSSLARPPLRFPPARPALSPSARRRCRVNWNQSSRPASHNAQRAARHIPSRP-------- 314
Query: 266 SAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRR 311
A L A AR P L P G A P A L P SP P R
Sbjct: 315 RASGLRARAARR-PGLDP--GPAPYPLTPAAL----RPGTSPHPGR 353
Score = 37.4 bits (85), Expect = 0.033
Identities = 73/320 (22%), Positives = 100/320 (31%), Gaps = 77/320 (24%)
Query: 207 APEGSVASLLPSAKPARAPRP-APRAREEAAAGSRGRGGAER---PAARGSAQQPPLARL 262
+P G SL P + +P P+++++A + G G R PA + QP
Sbjct: 34 SPPGEAYSL--PELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSPAHPWTTPQPG---- 87
Query: 263 LLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAG 322
PP QP AS PRL P A S + + PR G
Sbjct: 88 ----------------PPHQPGFNPASSPRLPLP-ADSEPDAYTSAPR-----------G 119
Query: 323 HGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAAR 382
G P + G R GG + + P +P+ +RR A
Sbjct: 120 SG---PTYCAGAGN-----SRAGGGLTKYNSAHSSSRVPRPRLPS---------QRRGA- 161
Query: 383 QWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIF--AAGP 440
G GPG R QG G R RG RP P GA G
Sbjct: 162 ---SCGLGPGPESRAARQGLGGRSARARTRRGPHRTRRPEPGPHHTGARQAGPLPGTRGR 218
Query: 441 RLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSV 500
+A + A P H ++R GR SP +S
Sbjct: 219 TRAAGTGSAARGPARHLRGGSVAAAAAARCLGLSPPGRSRLFSPRSSL------------ 266
Query: 501 NSHPSRSPYNWSPPSPSVPP 520
+R P + P P++ P
Sbjct: 267 ----ARPPLRFPPARPALSP 282
>gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo
sapiens]
Length = 355
Score = 58.5 bits (140), Expect = 1e-08
Identities = 85/308 (27%), Positives = 106/308 (34%), Gaps = 44/308 (14%)
Query: 97 PFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREP-- 154
PF P + + K G+ G G + P P P SPR P
Sbjct: 46 PFKKSKPFLPQSKQKADTETIGSSGGSRGPSPAHPWTTPQPGPPHQPGFNPASSPRLPLP 105
Query: 155 ---TPPGRLSAPPRHGP-------HPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSH 204
P SAP GP + ++ + + S RVPR + Q
Sbjct: 106 ADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGLTKYNSAHSSSRVPRPRLPSQRRGASCGL 165
Query: 205 FLAPEGSVASLLPSAKPARA-----------PRPAPRAREEAAAGS-RGRGGAERPAARG 252
PE A + ARA P P P AG G G R A G
Sbjct: 166 GPGPESRAARQGLGGRSARARTRRGPHRTRRPEPGPHHTGARQAGPLPGTRGRTRAAGTG 225
Query: 253 SAQQPPLARLLLASAVSLAAS---LARSPPP----LQPRLGSASPPRLAAPLAGSRAPSL 305
SA + P AR L +V+ AA+ L SPP PR A PP P + +PS
Sbjct: 226 SAARGP-ARHLRGGSVAAAAAARCLGLSPPGRSRLFSPRSSLARPPLRFPPARPALSPSA 284
Query: 306 SPFPRRCRRRAERS--PAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSP 363
RRCR +S PA H + R + +R R G R RR G G
Sbjct: 285 R---RRCRVNWNQSSRPASH------NAQRAARHIPSRPRASGLRARA-ARRPGLDPGPA 334
Query: 364 PIPAGPAA 371
P P PAA
Sbjct: 335 PYPLTPAA 342
Score = 39.3 bits (90), Expect = 0.009
Identities = 65/226 (28%), Positives = 76/226 (33%), Gaps = 44/226 (19%)
Query: 103 PHQERGRS---KPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGR 159
P Q RG S P P R+G G+ R RR H R P P
Sbjct: 155 PSQRRGASCGLGPGPESRAARQGLGGRSARAR------------TRRGPHRTRRPEPGPH 202
Query: 160 LSAPPRHGPHPQSFRRPSAHPPG---RGSGRVPRGQPEQQAWEQRS--------SHFLAP 208
+ + GP P + R A G RG R RG A R S +P
Sbjct: 203 HTGARQAGPLPGTRGRTRAAGTGSAARGPARHLRGGSVAAAAAARCLGLSPPGRSRLFSP 262
Query: 209 EGSVAS---LLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLA 265
S+A P A+PA +P R R SR + AAR +P
Sbjct: 263 RSSLARPPLRFPPARPALSPSARRRCRVNWNQSSRPASHNAQRAARHIPSRP-------- 314
Query: 266 SAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRR 311
A L A AR P L P G A P A L P SP P R
Sbjct: 315 RASGLRARAARR-PGLDP--GPAPYPLTPAAL----RPGTSPHPGR 353
Score = 37.4 bits (85), Expect = 0.033
Identities = 73/320 (22%), Positives = 100/320 (31%), Gaps = 77/320 (24%)
Query: 207 APEGSVASLLPSAKPARAPRP-APRAREEAAAGSRGRGGAER---PAARGSAQQPPLARL 262
+P G SL P + +P P+++++A + G G R PA + QP
Sbjct: 34 SPPGEAYSL--PELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSPAHPWTTPQPG---- 87
Query: 263 LLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAG 322
PP QP AS PRL P A S + + PR G
Sbjct: 88 ----------------PPHQPGFNPASSPRLPLP-ADSEPDAYTSAPR-----------G 119
Query: 323 HGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAAR 382
G P + G R GG + + P +P+ +RR A
Sbjct: 120 SG---PTYCAGAGN-----SRAGGGLTKYNSAHSSSRVPRPRLPS---------QRRGA- 161
Query: 383 QWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIF--AAGP 440
G GPG R QG G R RG RP P GA G
Sbjct: 162 ---SCGLGPGPESRAARQGLGGRSARARTRRGPHRTRRPEPGPHHTGARQAGPLPGTRGR 218
Query: 441 RLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSV 500
+A + A P H ++R GR SP +S
Sbjct: 219 TRAAGTGSAARGPARHLRGGSVAAAAAARCLGLSPPGRSRLFSPRSSL------------ 266
Query: 501 NSHPSRSPYNWSPPSPSVPP 520
+R P + P P++ P
Sbjct: 267 ----ARPPLRFPPARPALSP 282
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 58.5 bits (140), Expect = 1e-08
Identities = 146/555 (26%), Positives = 181/555 (32%), Gaps = 109/555 (19%)
Query: 36 SPRGRDGPWRHVETFPRARGVE-VASGRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFH 94
SPR GP + T GV V GRT P P P G + AP
Sbjct: 1764 SPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCL 1823
Query: 95 FQPFLSL---SPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSP 151
QP SP Q+R RS P T E L+ P
Sbjct: 1824 AQPAAPAKVPSPGQQRSRSLHRPA-------------------KTSELATLS-----QPP 1859
Query: 152 REPTPPGRLSAPPRHGPH---PQSFRRPSAHPP---------GRGSGRVPRGQPE----Q 195
R TPP RL+ P P S P PP G G+ VP+ +
Sbjct: 1860 RSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPARTLLAK 1919
Query: 196 QAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGG----------- 244
Q QRS + A P P P PR R AG RGG
Sbjct: 1920 QHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGRAGTEAGPGARGGRLGLVRVASAL 1979
Query: 245 ------AERPAARGS----AQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLA 294
++R R + P L R S +S A S A +P PR G + P A
Sbjct: 1980 SSGSESSDRSGFRRQLTFIKESPGLRR--RRSELSSAESAASAPQGASPRRGRPALP--A 2035
Query: 295 APLAGSR------APSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEE 348
L SR AP P P R R A R G P R+ S + R E
Sbjct: 2036 VFLCSSRCEELRAAPRQGPAPARQRPPAARPSPGE-RPARRTTSESPSRLPVRAPAARPE 2094
Query: 349 RRVR-GRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQG---EGV 404
R ++ P A PAAP A R R G P PR A G +
Sbjct: 2095 TVKRYASLPHISVARRPDGAVPAAPASADAAR-----RSSDGEPRPLPRVAAPGTTWRRI 2149
Query: 405 RGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPS-AEAEEVPGGHTASNPTY 463
R P S+ L + +G P A PR ++ + + EEV T S+ +
Sbjct: 2150 RDEDVPHILRST--LPATALPLRGSTPEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSP 2207
Query: 464 EPLSSRRTKAPSEGR--------DSPSSPATSTHYLDRESGLG--------SVNSHPSRS 507
+ AP+ G+ D PS GLG S + PSRS
Sbjct: 2208 SLETREPPGAPAGGQLSLLGSDVDGPSLAKAPISAPFVHEGLGVAVGGFPASRHGSPSRS 2267
Query: 508 ----PYNWSPPSPSV 518
P+N+ PSP V
Sbjct: 2268 ARVPPFNY-VPSPMV 2281
Score = 56.6 bits (135), Expect = 5e-08
Identities = 112/409 (27%), Positives = 144/409 (35%), Gaps = 71/409 (17%)
Query: 128 KEGRGSHPTPEPQRLAARRWLHSPREPT---PPGRLSAPPRHGPHPQSFRRPSAHPPGRG 184
+E + PTP +R +A PR T P GR AP S P+A PP R
Sbjct: 1516 EEPPAAAPTPTHRRTSA-----IPRAFTRERPQGRKEAPA------PSKAAPAAPPPART 1564
Query: 185 SGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGG 244
QP A E + L+ S AS L +P+ P PR RE A G GG
Sbjct: 1565 -------QPSLIADETPPCYSLS---SSASSLSEPEPSEPPAVHPRGREPAVTKDPGPGG 1614
Query: 245 AERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPS 304
R S+ P A LL +S ++L R PP+ S R P RA
Sbjct: 1615 -----GRDSSPSPRAAEELLQRCIS--SALPRRRPPV-------SGLRRRKP----RATR 1656
Query: 305 LSPFPRRCRRRAERSPAGHGLPLP------RSLSRGG--------EVVGARRRRGGEERR 350
L P R AG R++ G + A R E
Sbjct: 1657 LDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSESDS 1716
Query: 351 VRGRRQGCALGSPPIPAGPAAPGRA-GERRAARQWRKRGGG---PGVSPREGAQGEGVRG 406
+ G ++GS P +A GE +AR+ KRG SPR A E RG
Sbjct: 1717 ILSFVSGLSVGSTLQPPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRG 1776
Query: 407 ------GVTPRARGSSTCLRPSPATW---QGGAPYRAI--FAAGPRLSAPSAEAEEVPGG 455
GV RG + PSPA +G RA A P L+ P+A A+ G
Sbjct: 1777 TQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPG 1836
Query: 456 HTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHP 504
S + P + S+ S + PA S S S P
Sbjct: 1837 QQRSRSLHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQP 1885
Score = 45.4 bits (106), Expect = 1e-04
Identities = 87/318 (27%), Positives = 106/318 (33%), Gaps = 66/318 (20%)
Query: 34 DPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAPQTAPGF 93
+P PRGR G E P ARG G LV A +G GF
Sbjct: 1950 EPGPRGRAG----TEAGPGARG-----------GRLGLVRVASALSSGS---ESSDRSGF 1991
Query: 94 HFQ-PFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPR 152
Q F+ SP R RS+ S S + + GR + P +L S R
Sbjct: 1992 RRQLTFIKESPGLRRRRSELSSAESAASAPQGASPRRGRPALPAV---------FLCSSR 2042
Query: 153 EPTPPGRLSAPPRHGPHPQSFRRPSAHP--------------PGRGSGRVPRGQPEQQAW 198
L A PR GP P R P+A P P R R P +PE
Sbjct: 2043 CE----ELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAARPETVKR 2098
Query: 199 EQRSSHFLA---PEGSVASLLPSAKPAR-----APRPAPRAREEAAAGSRGRGGAERPAA 250
H P+G+V + SA AR PRP PR AA G+ R +
Sbjct: 2099 YASLPHISVARRPDGAVPAAPASADAARRSSDGEPRPLPRV---AAPGTTWRRIRDEDVP 2155
Query: 251 RGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLA-GSRAPSLSPFP 309
P L L S PPP + +AAP S +PSL
Sbjct: 2156 HILRSTLPATALPLRG--STPEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLE--- 2210
Query: 310 RRCRRRAERSPAGHGLPL 327
R +PAG L L
Sbjct: 2211 ---TREPPGAPAGGQLSL 2225
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 58.2 bits (139), Expect = 2e-08
Identities = 97/365 (26%), Positives = 130/365 (35%), Gaps = 48/365 (13%)
Query: 174 RRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSV-----ASLLPSAKPARAPRPA 228
R P+A PG + R P + L G+V A A P A
Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
Query: 229 PRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSL--AASLARSPPPLQPRLG 286
PRA +AG+ R A RP A G ++ P A+ VS AS P PL +
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134
Query: 287 SASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLP----RSLSRGGEVVGARR 342
S A + AP S RR + S G P P RS + G EV R
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARR--DTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192
Query: 343 RRGGEER-RVRGRRQGCALGS-----PPIPAGPAAPGRAGE-RRAARQWRKRGGGPGVSP 395
R G R+ + S P PA P G +R A + P SP
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 396 REGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGG 455
G RG TPRA + +P P Q P P+++ P +A G
Sbjct: 253 --ARSGPSARG--TPRAPAHPS--QPKPKGLQALRP--------PQVTPPRKDAAPALGP 298
Query: 456 HTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPS 515
++S PL++ A + + P+ PAT S + +P +PPS
Sbjct: 299 LSSS-----PLATPSPSAALQSQAPPTLPATPH---------SSSLTCQLATPLPLAPPS 344
Query: 516 PSVPP 520
PS PP
Sbjct: 345 PSAPP 349
Score = 55.8 bits (133), Expect = 9e-08
Identities = 114/486 (23%), Positives = 167/486 (34%), Gaps = 89/486 (18%)
Query: 57 EVASGRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPV 116
E A G T P+ P R AG P + P GR + +PP
Sbjct: 60 ERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRP-------------PASGRGERAPPA 106
Query: 117 SGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRP 176
T G GR S T P L + S E G+ + P+ RR
Sbjct: 107 KNTSPGPVSS--PGRASGTT-RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD 163
Query: 177 SAHP-PGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKP---ARAPRPAPRAR 232
++ P PG S + R S E + PSA+P PR + +
Sbjct: 164 TSGPTPGTPSPAMAR-----------RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 212
Query: 233 EEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPP-----------PL 281
E + RP+A G Q+P +R L +SA L+ S ARS P P
Sbjct: 213 SEHSTTEPSPAARRRPSAGGGLQRPA-SRSLSSSATPLS-SPARSGPSARGTPRAPAHPS 270
Query: 282 QPR---LGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVV 338
QP+ L + PP++ P + AP+L P SP P S+ +
Sbjct: 271 QPKPKGLQALRPPQVTPPRKDA-APALGPL--------SSSPLATPSPSAALQSQAPPTL 321
Query: 339 GARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREG 398
A C L +P +P P +P A + P P +
Sbjct: 322 PATPHSSSLT---------CQLATP-LPLAPPSPS------APPSLQTLPSPPATPPSQA 365
Query: 399 AQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTA 458
G +P + + + L P + P +A P L+ P +A P
Sbjct: 366 TTSLG-----SPTLQATHSFLPSPPLSPLATPPPQA----PPALALPPLQAPPSP----P 412
Query: 459 SNPTYEPLSSRRTKAPSEGR----DSPSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPP 514
++P PL++ +AP+ +P SP S S S PS +P + +PP
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472
Query: 515 SPSVPP 520
S + PP
Sbjct: 473 SLAAPP 478
Score = 46.2 bits (108), Expect = 7e-05
Identities = 102/440 (23%), Positives = 139/440 (31%), Gaps = 50/440 (11%)
Query: 86 APQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAAR 145
+P P P +P + S SP + T + P P LA
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403
Query: 146 RWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHF 205
L +P P+PP P P PQ+ + H + P P Q + +S
Sbjct: 404 P-LQAP--PSPPASPPLSPLATPSPQAPNALAVHLL-QAPFSPPPSPPVQAPFSPPASPP 459
Query: 206 LAPEGSVASLLP---SAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARL 262
++P + S P +A P + P P+P A P SA PP A
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVP-PSPPAS---------------PPMSPSATPPPQAPP 503
Query: 263 LLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCR--------- 313
LA+ LA+ PP P L A+PP A P + P +PF
Sbjct: 504 PLAAP---PLQLAKPPPQAPPAL--ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
Query: 314 -RRAERSPAGHGLPLPRSLSRGGEVVGARR-RRGGEERRVRGRRQGCAL--GSPPIPAGP 369
+A A L +P S + RR G + V G R AL G PP P+
Sbjct: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
Query: 370 AAPGRAGERRAARQWRKRGGGPGVSPREGAQG--EGVRGGVTPRARGSSTCLRPSPATWQ 427
+ +G A S E +G G GG + PA W
Sbjct: 619 PSSTLSGPDLAGH------SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 672
Query: 428 GGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATS 487
G F P P A PG YE D SP TS
Sbjct: 673 RGPAPPLAFRGAPGAPLPWPPATG-PGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 731
Query: 488 THYLDRESGLGSVNSHPSRS 507
+G G+ + P ++
Sbjct: 732 GGKAAAGAGAGASSRSPKQA 751
Score = 37.7 bits (86), Expect = 0.026
Identities = 79/309 (25%), Positives = 105/309 (33%), Gaps = 59/309 (19%)
Query: 26 NTSQSESFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCE 85
+ S+ + +PSP R P G++ + R+ + PL + PAR +G
Sbjct: 211 SASEHSTTEPSPAARRRP-------SAGGGLQRPASRSLSSSATPL--SSPAR-SGPSAR 260
Query: 86 APQTAPGFHFQP----FLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQR 141
AP QP +L P Q K + P G S P P
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL-----------SSSPLATPSP 309
Query: 142 LAARRWLHSPREPTPPGRLS-----------APPRHGPHP--QSFRRPSAHPPGRGSGRV 188
AA + P P P S APP P Q+ P A PP + + +
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
Query: 189 PRGQPEQQAWEQRSSHFLAPEGSVASLL---PSAKPARAPRPAPRAREEAAAGSRGRGGA 245
G P QA +H P ++ L P A PA A P A+
Sbjct: 370 --GSPTLQA-----THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS---- 418
Query: 246 ERPAARGSAQQP-PLARLLLASAVSLAAS----LARSPPPLQPRLGSASPPRLAAPLAGS 300
P A S Q P LA LL + S S SPP P SA+PP A P +
Sbjct: 419 --PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
Query: 301 RAPSLSPFP 309
+ P P
Sbjct: 477 PPLQVPPSP 485
Score = 33.1 bits (74), Expect = 0.63
Identities = 55/220 (25%), Positives = 76/220 (34%), Gaps = 25/220 (11%)
Query: 70 PLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKT---GQ 126
PL+ PP+ A +AP+ P P S+S + P PP +R + G
Sbjct: 569 PLLQVPPSPPASPTLQAPRRPPTPG--PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626
Query: 127 WKEGRGSHPTPEPQRLAARRWLHSPR-----EPTPPGRLSAPPRHGPHPQSFRRPSAHPP 181
G S T P+ L R + P P P L+A HP ++ R A P
Sbjct: 627 DLAGHSSSATSTPEEL--RGYDSGPEGGAAASPPPDAELAAC-----HPAAWSRGPAPPL 679
Query: 182 G-RGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSR 240
RG+ P P E A A P P+P AA
Sbjct: 680 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 739
Query: 241 GRGGAERPAARGSAQQPPLARL-------LLASAVSLAAS 273
G G + R + + PL L LL+ + LAA+
Sbjct: 740 GAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 779
>gi|150170699 kinesin family member 26A [Homo sapiens]
Length = 1882
Score = 58.2 bits (139), Expect = 2e-08
Identities = 106/434 (24%), Positives = 144/434 (33%), Gaps = 54/434 (12%)
Query: 55 GVEVASGRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPF--------LSLSPHQE 106
G EVA+ R P+ + PP RR A + P L SP +
Sbjct: 1286 GCEVAARAAR--RPEAVARIPPLRRGATTLGVTTPAVSWGDAPTEVVACSGSLKASPTSK 1343
Query: 107 RGRS-------KPS---PPVSGTRRGKTGQWKEGRGSHP-TPEPQRLAARRWLHSPREPT 155
+G + +PS PP TR+ Q + P P R+ A L EP
Sbjct: 1344 KGLAPKAGFLPRPSGAAPPAPPTRKSSLEQRSSPASAPPHAVNPARVGAAAVLRGEEEPR 1403
Query: 156 PPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLA--PEGSVA 213
P R R R +G + E A P +V
Sbjct: 1404 PSSRADHSVPRATSSLKARASKVEAAHRLAGHASLERYEGLAHSSSKGREAPGRPPRAVP 1463
Query: 214 SL-LPSAKPARAPRPAPRAREEAAAGSR----GRGGAERPAARGSAQQPPLARLLLASAV 268
L +P + P P PA R+ A G+ G G A GS P +L AS
Sbjct: 1464 KLGVPPSSPTHGPAPACRSGAAKAVGAPKPPVGGGKGRGLVAGGSRALGPSVKLSTASVT 1523
Query: 269 SLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLP 328
RSP P G + PR A P G++A + + RA S H L
Sbjct: 1524 G------RSPGG--PVAGPRAAPR-AGPSVGAKAGRGTVMGTKQALRAAHSRV-HELSAS 1573
Query: 329 RSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRG 388
+ RGG G+ G + G +G P GPA P + A R+ ++
Sbjct: 1574 GAPGRGGSSWGSADSDSGHD-------SGVNVGEERPPTGPALPSPYSKVTAPRRPQRYS 1626
Query: 389 GGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAE 448
G G+ V G P A G + S + + R A G SAP +
Sbjct: 1627 SG------HGSDNSSVLSGELPPAMGRTALFHHSGGSSGYESLRRDSEATGSASSAPDSM 1680
Query: 449 AEE---VPGGHTAS 459
+E PG T S
Sbjct: 1681 SESGAASPGARTRS 1694
Score = 46.2 bits (108), Expect = 7e-05
Identities = 85/346 (24%), Positives = 125/346 (36%), Gaps = 45/346 (13%)
Query: 154 PTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQA-WEQRSSHFLAPE--- 209
PT S + P + P A R SG P P +++ EQRSS AP
Sbjct: 1326 PTEVVACSGSLKASPTSKKGLAPKAGFLPRPSGAAPPAPPTRKSSLEQRSSPASAPPHAV 1385
Query: 210 -----GSVASLLPSAKP---ARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLAR 261
G+ A L +P +RA PRA A + A R A S ++
Sbjct: 1386 NPARVGAAAVLRGEEEPRPSSRADHSVPRATSSLKARASKVEAAHRLAGHASLER----- 1440
Query: 262 LLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPA 321
++ ++S R P PR + P+L P + +P+ P P CR A ++
Sbjct: 1441 ---YEGLAHSSSKGREAPGRPPR----AVPKLGVPPS---SPTHGPAPA-CRSGAAKAVG 1489
Query: 322 GHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAA 381
P+ RG V G R G + G + G P AGP A RAG A
Sbjct: 1490 APKPPVGGGKGRG-LVAGGSRALGPSVKLSTASVTGRSPGGPV--AGPRAAPRAGPSVGA 1546
Query: 382 RQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPR 441
K G G + ++ + A L S A +GG+ + + +
Sbjct: 1547 ----KAGRGTVMGTKQALRA----------AHSRVHELSASGAPGRGGSSWGSADSDSGH 1592
Query: 442 LSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATS 487
S + E P G +P + + RR + S G S +S S
Sbjct: 1593 DSGVNVGEERPPTGPALPSPYSKVTAPRRPQRYSSGHGSDNSSVLS 1638
Score = 45.4 bits (106), Expect = 1e-04
Identities = 74/320 (23%), Positives = 115/320 (35%), Gaps = 48/320 (15%)
Query: 185 SGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAA------- 237
+ + P G P + A SSH + ++ + +R P P PR ++ A
Sbjct: 1087 TSQAPEGGPLEGAAWAGSSHGSSISSWLSEVSVCTADSRDPTPQPRFSPDSLAGLDPGGP 1146
Query: 238 ---------GSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSA 288
GS G G +RP + G P A++A S P +P+ G +
Sbjct: 1147 PALDGSLGDGSSGFLGPDRPDSPGPTWGP---------CPGEVAAVAPSRPGREPQAGPS 1197
Query: 289 SPPRLAAPLAGS--RAPSLSPFPRR--CRRRAERSPAGHGLPLPRSLSRGGEVVGARRRR 344
A + S R P + R C R + P GL L R GE
Sbjct: 1198 RWASAAQTIHSSLPRKPRTASATTRVGCARLGQSPPGRGGLFEDPWLLRVGEC------- 1250
Query: 345 GGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGV 404
+ GR LGSP +P A ++ G V+ R + E V
Sbjct: 1251 -DTQAASAGRAPSPTLGSPRLPEAQVMLACA---------QRVVDGCEVAARAARRPEAV 1300
Query: 405 RGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPT-Y 463
+ P RG++T +PA G AP + +G ++P+++ P P+
Sbjct: 1301 -ARIPPLRRGATTLGVTTPAVSWGDAPTEVVACSGSLKASPTSKKGLAPKAGFLPRPSGA 1359
Query: 464 EPLSSRRTKAPSEGRDSPSS 483
P + K+ E R SP+S
Sbjct: 1360 APPAPPTRKSSLEQRSSPAS 1379
Score = 42.7 bits (99), Expect = 8e-04
Identities = 61/241 (25%), Positives = 85/241 (35%), Gaps = 45/241 (18%)
Query: 67 GPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQE--RGRSKPSPPVSGTRRGKT 124
GP V PA + P+ A F F L E G PS GT +
Sbjct: 810 GPPDFVPIIPALSRHRPSKGPRDADHFRCSTFAELQERLECMDGNEGPSGGPGGTDGAQA 869
Query: 125 GQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRG 184
+ GR P P+ + R+ + +P + P S P H P+ +
Sbjct: 870 SPARGGRKPSP---PEAASPRKAVGTPMAASTPRGSSGPDTHQGTPEPCK---------- 916
Query: 185 SGRVPRG--QPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGR 242
+ G + + AW + L PE + S +P +P P P EA
Sbjct: 917 --AIVWGDQREDSSAWPE----LLVPEKAAVS--GGRRPLPSPAPPPPQLLEACRAPEEP 968
Query: 243 GGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRA 302
GG G A+ PP V ++ +A S P L A+ PRLA AGSR
Sbjct: 969 GGG---GTDGVARTPP---------VGMSGQVAGS-----PMLPGATCPRLA---AGSRC 1008
Query: 303 P 303
P
Sbjct: 1009 P 1009
Score = 41.2 bits (95), Expect = 0.002
Identities = 95/385 (24%), Positives = 126/385 (32%), Gaps = 67/385 (17%)
Query: 132 GSHPTPEPQRLA-ARRWLHS--PREP----------------TPPGR--LSAPP---RHG 167
G P P R A A + +HS PR+P +PPGR L P R G
Sbjct: 1189 GREPQAGPSRWASAAQTIHSSLPRKPRTASATTRVGCARLGQSPPGRGGLFEDPWLLRVG 1248
Query: 168 P-HPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPR 226
Q+ A P GS R+P Q A QR +G + + +P R
Sbjct: 1249 ECDTQAASAGRAPSPTLGSPRLPEAQV-MLACAQR-----VVDGCEVAARAARRPEAVAR 1302
Query: 227 PAPRAREEAAAG------SRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPP 280
P R G S G E A GS + P ++ LA + + PP
Sbjct: 1303 IPPLRRGATTLGVTTPAVSWGDAPTEVVACSGSLKASPTSKKGLAPKAGFLPRPSGAAPP 1362
Query: 281 LQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSP-----AGHGLPLPRSL--SR 333
P S+ R + A A + + R E P A H +P S +R
Sbjct: 1363 APPTRKSSLEQRSSPASAPPHAVNPARVGAAAVLRGEEEPRPSSRADHSVPRATSSLKAR 1422
Query: 334 GGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGV 393
+V A R G R +G A S G APGR P
Sbjct: 1423 ASKVEAAHRLAGHASLE---RYEGLAHSSSK---GREAPGRP---------------PRA 1461
Query: 394 SPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVP 453
P+ G G P R + +P GG R + A G R PS +
Sbjct: 1462 VPKLGVPPSSPTHGPAPACRSGAAKAVGAPKPPVGGGKGRGLVAGGSRALGPSVKLSTAS 1521
Query: 454 -GGHTASNPTYEPLSSRRTKAPSEG 477
G + P P ++ R PS G
Sbjct: 1522 VTGRSPGGPVAGPRAAPRA-GPSVG 1545
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 57.8 bits (138), Expect = 2e-08
Identities = 86/323 (26%), Positives = 122/323 (37%), Gaps = 51/323 (15%)
Query: 232 REEAAAGSRGRGGAER------PAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPR- 284
R++A AG+ R A R P GS + PP + A ++ R P L R
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP--LAERA 62
Query: 285 --LGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARR 342
+G A+ P +AP AG S P R ER+P P +S G G R
Sbjct: 63 GGIGGATIPE-SAPRAGPTRTSRPP----ASGRGERAPPAKNTS-PGPVSSPGRASGTTR 116
Query: 343 ---------RRGGEERRVRGR------RQGCALGSPPIPAGPA--APGRAGERRAARQWR 385
R EE RG+ R + G+ +GP P A RR+
Sbjct: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176
Query: 386 KRG-GGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSA 444
+ G P S R EG R V+ + S+T PSPA R +AG L
Sbjct: 177 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT--EPSPAA-------RRRPSAGGGLQR 227
Query: 445 PSAEAEEVPGGHTASNPTYEPLSSRRTKAPS-------EGRDSPSSPATSTHYLDRESGL 497
P++ + +S P + +AP+ +G + P + D L
Sbjct: 228 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287
Query: 498 GSVNSHPSRSPYNWSPPSPSVPP 520
G ++S P +P +PPSPS PP
Sbjct: 288 GPLSSSPLATPSPSAPPSPSAPP 310
Score = 52.8 bits (125), Expect = 8e-07
Identities = 96/377 (25%), Positives = 140/377 (37%), Gaps = 46/377 (12%)
Query: 157 PGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLL 216
PG L+ P P P P+A +G V R ++A + PE +
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI--PESA----- 74
Query: 217 PSAKPARAPRPAPRAREEAA--AGSRGRGGAERPA-ARGSAQQPPLARL-LLASAVSLAA 272
P A P R RP R E A A + G P A G+ + PL + L SA A
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134
Query: 273 SLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLS 332
+ P + L + + + P G+ +P+++ RR+ + GLP P +
Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA-------RRSRAAGTEVGLPRPAPSA 187
Query: 333 RGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGE-RRAARQWRKRGGGP 391
R R G + V + + P PA P G +R A + P
Sbjct: 188 R------PRPPTEGPRKSVSSASEHST--TEPSPAARRRPSAGGGLQRPASRSLSSSATP 239
Query: 392 GVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYR-------AIFAAGPRLSA 444
SP G RG TPRA + +P P Q P + A A GP S+
Sbjct: 240 LSSPARS--GPSARG--TPRAPAHPS--QPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293
Query: 445 PSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPAT-STHYLDRESGLGSVNSH 503
P A ++ P+ + L S PS+ S SP +TH S L S
Sbjct: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH-----SFLPSPPLS 348
Query: 504 PSRSPYNWSPPSPSVPP 520
P +P +PP+ ++PP
Sbjct: 349 PLATPPPQAPPALALPP 365
Score = 50.8 bits (120), Expect = 3e-06
Identities = 106/435 (24%), Positives = 136/435 (31%), Gaps = 90/435 (20%)
Query: 154 PTPPGRLSAPPRHGPHPQSF--------RRPSAHPPGR-GSGRVPRGQPEQQAWEQRSSH 204
P PPG PP P R+P A G G +P P +A R+S
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP--RAGPTRTSR 84
Query: 205 FLAPEGSVASLLPSAK-----PARAPRPAPRAREEAAAGSRG-RGGAERPAARGSAQQPP 258
P P AK P +P A G +G R AE ARG A + P
Sbjct: 85 --PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 142
Query: 259 LARLLLASA----------------------VSLAASLARSPPPLQPRLGSASPPRLAAP 296
L A A L R P +PR + P + +
Sbjct: 143 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202
Query: 297 LAGSRAPSLSPFPRRCRRRAERSPAGHGL--PLPRSLSRGGEVVGARRRRGGEERRVRGR 354
+ SP RR R AG GL P RSLS + + R G R
Sbjct: 203 ASEHSTTEPSPAARR------RPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR----- 251
Query: 355 RQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARG 414
G+P PA P+ P G +A R + +P G +P A
Sbjct: 252 ------GTPRAPAHPSQPKPKG-LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP 304
Query: 415 SSTC------------LRPSPATWQGGAPYRAI---FAAGPRLSAPSAEAEEVPGGHTA- 458
S + PS AT G+P F P LS + + P
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 364
Query: 459 ------SNPTYEPLSSRRTKAPSEGR-------DSPSSPATSTHYLDRESGLGSVNSHPS 505
S P PLS T +P +P SP S S S PS
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424
Query: 506 RSPYNWSPPSPSVPP 520
+P + +PPS + PP
Sbjct: 425 ATPPSQAPPSLAAPP 439
Score = 50.4 bits (119), Expect = 4e-06
Identities = 121/527 (22%), Positives = 164/527 (31%), Gaps = 70/527 (13%)
Query: 12 MTRRASPVFTGFCVNTSQSESFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPL 71
+ R AS + S PS RG H P+ +G++ +P
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-PKPKGLQAL---------RPP 274
Query: 72 VDTPPARRA----GELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQW 127
TPP + A G L +P P P S P + S P+ P S
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334
Query: 128 KEGRGSH---------PTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSA 178
+ S TP PQ A P+PP P P PQ+ +
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394
Query: 179 HPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLP---SAKPARAPRPAPRAREEA 235
H + P P Q + +S ++P + S P +A P + P P+P A
Sbjct: 395 HLL-QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-PSPPAS--- 449
Query: 236 AAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAA 295
P SA PP A LA+ LA+ PP P L A+PP A
Sbjct: 450 ------------PPMSPSATPPPQAPPPLAAP---PLQLAKPPPQAPPAL--ATPPLQAL 492
Query: 296 PLAGSRAPSLSPFPRRCR----------RRAERSPAGHGLPLPRSLSRGGEVVGARR-RR 344
P + P +PF +A A L +P S + RR
Sbjct: 493 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 552
Query: 345 GGEERRVRGRRQGCAL--GSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQG- 401
G + V G R AL G PP P+ + +G A S E +G
Sbjct: 553 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH------SSSATSTPEELRGY 606
Query: 402 -EGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASN 460
G GG + PA W G F P P A PG
Sbjct: 607 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG-PGSADGLC 665
Query: 461 PTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRS 507
YE D SP TS +G G+ + P ++
Sbjct: 666 TIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 712
Score = 50.1 bits (118), Expect = 5e-06
Identities = 80/298 (26%), Positives = 104/298 (34%), Gaps = 77/298 (25%)
Query: 59 ASGRTRWTGPQPL------VDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKP 112
ASG TR P PL + G+ EAP+ + +LS R S P
Sbjct: 111 ASGTTR---PGPLGQKGLRISAEETVARGKATEAPKRS---------ALSAGARRDTSGP 158
Query: 113 SPPV-----------SGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGR-- 159
+P +GT G R PT P++ + HS EP+P R
Sbjct: 159 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 218
Query: 160 ---------------------LSAPPRHGPHPQSFRRPSAH-----PPGRGSGRVPRGQP 193
LS+P R GP + R AH P G + R P+ P
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 278
Query: 194 EQQ----AWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPA 249
++ A SS LA A PSA P+ P+P A + A + G A
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA-TTSLGSPTLQA 337
Query: 250 ARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSP 307
PPL + LA PP P L A PP L AP + +P LSP
Sbjct: 338 THSFLPSPPL------------SPLATPPPQAPPAL--ALPP-LQAPPSPPASPPLSP 380
Score = 47.4 bits (111), Expect = 3e-05
Identities = 88/334 (26%), Positives = 113/334 (33%), Gaps = 63/334 (18%)
Query: 35 PSPRGRDGPWRHVE-TFPRARGVEV-------ASGRTRWTGPQPLVDTPP----ARRAGE 82
P P G+ G E T R + E A R +GP P +P +R AG
Sbjct: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176
Query: 83 LCEAPQTAPGFHFQPFL-----SLSPHQERGRSKPSPPV--------------------- 116
P+ AP +P S+S E ++PSP
Sbjct: 177 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 236
Query: 117 -----SGTRRGKTGQWKEGRGSHPT-PEPQRLAARRWLHSPREPTPP--------GRLSA 162
S R G + + +HP+ P+P+ L A R P + TPP G LS+
Sbjct: 237 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR----PPQVTPPRKDAAPALGPLSS 292
Query: 163 PPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVAS--LLPSAK 220
P P P + PSA P + P P Q S A + S L P A
Sbjct: 293 SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 352
Query: 221 PARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQP-PLARLLLASAVSLAAS----LA 275
P PA A S P A S Q P LA LL + S S
Sbjct: 353 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412
Query: 276 RSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFP 309
SPP P SA+PP A P + + P P
Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446
Score = 33.1 bits (74), Expect = 0.63
Identities = 55/220 (25%), Positives = 76/220 (34%), Gaps = 25/220 (11%)
Query: 70 PLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKT---GQ 126
PL+ PP+ A +AP+ P P S+S + P PP +R + G
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPG--PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 587
Query: 127 WKEGRGSHPTPEPQRLAARRWLHSPR-----EPTPPGRLSAPPRHGPHPQSFRRPSAHPP 181
G S T P+ L R + P P P L+A HP ++ R A P
Sbjct: 588 DLAGHSSSATSTPEEL--RGYDSGPEGGAAASPPPDAELAAC-----HPAAWSRGPAPPL 640
Query: 182 G-RGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSR 240
RG+ P P E A A P P+P AA
Sbjct: 641 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 700
Query: 241 GRGGAERPAARGSAQQPPLARL-------LLASAVSLAAS 273
G G + R + + PL L LL+ + LAA+
Sbjct: 701 GAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 740
>gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo
sapiens]
Length = 459
Score = 57.8 bits (138), Expect = 2e-08
Identities = 125/449 (27%), Positives = 160/449 (35%), Gaps = 116/449 (25%)
Query: 66 TGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPH-------QERGRSKPSPPVSG 118
T Q VDT P + P QP + + + G +P+P +
Sbjct: 2 TAMQHCVDTVPMHNSHPPHPHPPVPVSGEIQPDIGQNSPLIFHIMCNDMGTLEPTPLL-- 59
Query: 119 TRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREP---------TPP---GRLSAPPRH 166
R K Q + GRG R AA L P EP TPP GR+S P
Sbjct: 60 --RRKAAQLQPGRGKSCGA---RRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPA-- 112
Query: 167 GPHPQSF---RRPS----------------AHPPGRGSGRVPR--GQPEQQAWEQRSSHF 205
PQ+F R P+ P GRG GR R PE A S
Sbjct: 113 ---PQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPS 169
Query: 206 LAPEGSVASLLPSAKPARAPRPAPRAREEA--AAGSRGRGGAER---PAARGSAQQPPLA 260
A GS +S + R+ R A + R A A G+ R ++ PA R A + P A
Sbjct: 170 PADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGA 229
Query: 261 RLLLA----------SAVSLA------ASLARSP----PPLQPRLGSASPPRLAAPLAGS 300
LL+ +A S+A SL R P PP P++ +A P A P G
Sbjct: 230 PRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPP--PQVLTAEPREDATPGEG- 286
Query: 301 RAPSLSPFPRRCRRRAERSPAGHG---LPLPRSLSRGGEVVGARRRRGGEERRVRGRRQG 357
R P P R R + PA G L L + RGG + RR G G
Sbjct: 287 RLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVGRGGTGSWSWRRGAGS-----AELPG 341
Query: 358 CALGSPPIPAGPAAPGRAGERRAARQWRK-----RGGGPGVSPRE--------GAQG--- 401
C+ + A G++ E R R+ RGGG GV+ E G +G
Sbjct: 342 CSCAQ--LAQQLARAGKSTESRNRLNGRRGGVEARGGGGGVARAERDDVLQGLGLRGTED 399
Query: 402 ----------EGVRGGVTPRARGSSTCLR 420
GVR G P RGSS R
Sbjct: 400 WCARRAPRTSSGVRRGAAPGFRGSSNTAR 428
Score = 37.4 bits (85), Expect = 0.033
Identities = 89/346 (25%), Positives = 104/346 (30%), Gaps = 92/346 (26%)
Query: 164 PRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPAR 223
P H HP P HPP SG + QP+ H + +
Sbjct: 12 PMHNSHP-----PHPHPPVPVSGEI---QPDIGQNSPLIFHIMCNDMGTLE--------- 54
Query: 224 APRPAPRAREEAAAGSRGRG---GAERPAARGSAQQPPLARLLLASAVSLAASLARSPPP 280
P P R +AA GRG GA R AA + PP + L PP
Sbjct: 55 ---PTPLLRRKAAQLQPGRGKSCGARR-AALPLLRYPP--------EPGVFPFLVLWTPP 102
Query: 281 LQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGA 340
P G SPP A LA +RSPA
Sbjct: 103 FAP--GRISPPAPQAFLA------------------QRSPA------------------- 123
Query: 341 RRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQ 400
R GG G+R+ PA G RR PG SP
Sbjct: 124 RASPGGGFTSAEGKRK----------TRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADP 173
Query: 401 GEGVRGGVTPRARGSS-TCLRPSPATWQG-GAPYRAIFAAGPRLSAPSAEAEEVPGGHTA 458
G PRAR SS L+P A GAP R+ A P AP A PG
Sbjct: 174 GSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP-PAPRFPASRRPGA--- 229
Query: 459 SNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHP 504
L SR + G +PS + L E G S P
Sbjct: 230 -----PRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPP 270
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 57.8 bits (138), Expect = 2e-08
Identities = 136/541 (25%), Positives = 174/541 (32%), Gaps = 140/541 (25%)
Query: 28 SQSESFDPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAP 87
S S PSPRG GP+ P + G AS + GP P DT R L +
Sbjct: 940 SSSGRLTPSPRG--GPFN-----PGSGGPLPASSPASFDGPSP-PDTRVGSREKSLYHSG 991
Query: 88 QTAPGFHFQPFLSL------SPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQR 141
P H P PH P PP T G P P R
Sbjct: 992 PLPPAHHHPPHHHHHHAPPPQPHHHHAHP-PHPPEMET------------GGSPDDPPPR 1038
Query: 142 LAA------RRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQ 195
LA R W PTP AP PS H G G +G P
Sbjct: 1039 LALGPQPSLRGWRGGGPSPTP----GAPS-----------PSHHGSAGGGGGSSQG-PAL 1082
Query: 196 QAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGG----AERPAAR 251
+ ++ L P + A++ A+ R R P ++ G +GG A P +
Sbjct: 1083 RYFQ------LPPRAASAAMYVPARSGRG-RKGPLVKQTKVEGEPQKGGGLPPAPSPTSP 1135
Query: 252 GSAQQPPLAR-------LLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPS 304
S Q PP + + + + A S + S Q A PP P G
Sbjct: 1136 ASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGG 1195
Query: 305 LSPFPRRCRRRAERSPAGHGLPLPRSLSR----------GGEVVGARRRRGGEERRVRGR 354
SP P SP+ +P P S S G +VGA RR GG + R R
Sbjct: 1196 SSPSPAPAMSPVPPSPSP--VPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEAR-R 1252
Query: 355 RQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARG 414
R L + AG+ GG G G+ G P R
Sbjct: 1253 RSTLFLSTD-----------AGDE---------DGGDG----------GLGTGAAPGPR- 1281
Query: 415 SSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTY----------E 464
LR S + +G +F+A P L SA + GG+ A + Y
Sbjct: 1282 ----LRHSKSIDEG------MFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTS 1331
Query: 465 PLSSRRTKAPSEGRD-SPSSP-----ATSTHYLDRESGLGSVNSHPSRSP---YNWSPPS 515
L R P G+ P+SP A L S G P R P Y PP+
Sbjct: 1332 FLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPT 1391
Query: 516 P 516
P
Sbjct: 1392 P 1392
Score = 37.7 bits (86), Expect = 0.026
Identities = 110/457 (24%), Positives = 142/457 (31%), Gaps = 134/457 (29%)
Query: 95 FQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGR-----------------GSHPTP 137
F P P ER P P R+ G ++ R GS P
Sbjct: 862 FDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIP 921
Query: 138 EPQRLAARRWLHS-PREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQ 196
P + +S P P+ GRL+ PR GP PG G
Sbjct: 922 PPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGP----------FNPGSGGP---------- 961
Query: 197 AWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQ 256
LP++ PA P+P + GSR + +
Sbjct: 962 -------------------LPASSPASFDGPSP---PDTRVGSREKSLYHSGPLPPAHHH 999
Query: 257 PPLARLLLASAVSLAASLARSPPPLQPRLGSA---SPPRLA----APLAGSRAPSLSPFP 309
PP A A P P + G + PPRLA L G R SP P
Sbjct: 1000 PPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTP 1059
Query: 310 RRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCAL---GSPPIP 366
SP+ HG S GG GG G QG AL PP
Sbjct: 1060 ------GAPSPSHHG-------SAGG---------GG------GSSQGPALRYFQLPPRA 1091
Query: 367 AGPA--APGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPA 424
A A P R+G R GP V + +GE +GG P A ++ P P
Sbjct: 1092 ASAAMYVPARSGRGRK---------GPLVKQTK-VEGEPQKGGGLPPAPSPTSPASPQPP 1141
Query: 425 TWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSP 484
P ++APS E +P S R ++ S + P+ P
Sbjct: 1142 ---------------PAVAAPS-EKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQP 1185
Query: 485 ATSTHYLDRESGLGSVNSHPSRSP-YNWSPPSPSVPP 520
+ G G S PS +P + PPSPS P
Sbjct: 1186 -------EPTGGGGGGGSSPSPAPAMSPVPPSPSPVP 1215
Score = 37.0 bits (84), Expect = 0.044
Identities = 98/409 (23%), Positives = 123/409 (30%), Gaps = 86/409 (21%)
Query: 149 HSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAP 208
H P P P A P+ GP P PPG SG E+ S H L
Sbjct: 1646 HPPGPPAPAAPAPAAPQPGPDP---------PPGTDSG------IEEVDSRSSSDHPLET 1690
Query: 209 EGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAV 268
S ++L + GS G GG A G A P L +A
Sbjct: 1691 ISSASTL--------------SSLSAEGGGSAGGGGG---AGAGVASGPELLDTYVAYLD 1733
Query: 269 SLAASLARSP-PPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPL 327
A + +P PP P+L +P +L G+ + L P P R P P
Sbjct: 1734 GQAFGGSSTPGPPYPPQL--MTPSKLRGRALGA-SGGLRPGP----SGGLRDPVTPTSPT 1786
Query: 328 PRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKR 387
G + + A R G G G P +P P P + R W +
Sbjct: 1787 VSVTGAGTDGLLALRACSGPP--TAGVAGGPVAVEPEVPPVP-LPTASSLPRKLLPWEEG 1843
Query: 388 GG-------GPGVSPREGA-------------------QGEGVRGGVTPRARGSSTCLRP 421
G GP P+ A G GG P ARG S
Sbjct: 1844 PGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGD 1903
Query: 422 SPATWQGGAPYRAIFAAGPRLSAPSAEA----------EEVPGGHTASNPTYEPLSSRRT 471
S P R RLS S + + P PT +S
Sbjct: 1904 SHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAA 1963
Query: 472 KAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSVPP 520
AP S SS +TST +L R P PSPS+ P
Sbjct: 1964 AAPGATSPSASSSSTSTRHLQGV-------EFEMRPPLLRRAPSPSLLP 2005
Score = 32.3 bits (72), Expect = 1.1
Identities = 113/473 (23%), Positives = 148/473 (31%), Gaps = 84/473 (17%)
Query: 74 TPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGRGS 133
+PPA R L P TAPG P L + G P+P G + W+ S
Sbjct: 1436 SPPAARRSLLHRLPPTAPG--VGPLL-----LQLGTEPPAP-----HPGVSKPWR----S 1479
Query: 134 HPTPEPQRLAAR-RWLHS--PREPTPPGRLSAPPRHGP--HPQSFRRPSAHPPGRGSGRV 188
EP+RL R+L + PR P GR P GP P S RR + PP S R
Sbjct: 1480 AAPEEPERLPLHVRFLENCQPRAPVTSGR-GPPSEDGPGVPPPSPRR--SVPPSPTSPRA 1536
Query: 189 PRGQ--------PEQQAWEQRSSHF-----LAPEGSVASLLPSAKPARAPRPAPRAREEA 235
P + + F L P ++ + P P P +
Sbjct: 1537 SEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGP-PHPLPDT 1595
Query: 236 AAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAA 295
A + PA A PP +S S + +A G PP A
Sbjct: 1596 PAPATPLPPVPPPAV---AAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPA 1652
Query: 296 PLA-GSRAPSLSPFP-----RRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEER 349
P A AP P P RS + H L ++S + GG
Sbjct: 1653 PAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPL---ETISSASTLSSLSAEGGGSAG 1709
Query: 350 RVRGRRQGCALGSPPIP-----------AGPAAPGRAGERRAARQWRKRGGGPGVSP--R 396
G G A G + G + PG + + RG G S R
Sbjct: 1710 GGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLR 1769
Query: 397 EGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGH 456
G G G+R VTP SP GA + A P+A V GG
Sbjct: 1770 PGPSG-GLRDPVTP----------TSPTVSVTGAGTDGLLALRACSGPPTA---GVAGGP 1815
Query: 457 TASNPTYEPLS-------SRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNS 502
A P P+ R+ EG P P + S L +V +
Sbjct: 1816 VAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKA 1868
Score = 30.4 bits (67), Expect = 4.1
Identities = 35/114 (30%), Positives = 42/114 (36%), Gaps = 11/114 (9%)
Query: 224 APRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARL--LLASAVSLAASLARSPPPL 281
A P P RE G PA+ +A++ L RL L L PP
Sbjct: 1410 ASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAP 1469
Query: 282 QPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAE----RSPA---GHGLPLP 328
P G + P R AAP R P F C+ RA R P G G+P P
Sbjct: 1470 HP--GVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPP 1521
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 57.4 bits (137), Expect = 3e-08
Identities = 108/400 (27%), Positives = 135/400 (33%), Gaps = 72/400 (18%)
Query: 35 PSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTP-PARRAGELCEAPQTAPGF 93
P P+G G P G + G+ GP + P PA + G+ E APG
Sbjct: 737 PGPKGDKGE-------PGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGG--APGL 787
Query: 94 HFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQWKE--GRGSHPTPEPQRLAARRWLHSP 151
P ++ R + PP G GQ E G+G P + P
Sbjct: 788 ---PGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG-----PP 839
Query: 152 REPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVP--RGQPEQQAWEQRSSHFLAPE 209
PPG + P P PQ + P G G+ P RG P S+ P
Sbjct: 840 GVAGPPG--GSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPG----SNGNPGPP 893
Query: 210 GSVASLLPSAKPARAPRPAPRAREEAAAGSRG----RGGAERPAARGS--AQQPPLARLL 263
G PS P + P P A A GS G +G A +P +GS AQ PP A
Sbjct: 894 G------PSGSPGKDGPPGP-AGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGP 946
Query: 264 LASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGH 323
L A A PP + GS P + A LS ER P G
Sbjct: 947 LGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLS---------GERGPPG- 996
Query: 324 GLPLPRSLSRGGEVVGARRRRG--------GEERRVRGRRQGCALGSPPIPAGPAAPGRA 375
P+ L G R G G + G+ GSP P P PG
Sbjct: 997 ----PQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPP 1052
Query: 376 GERRAARQWRKRG--------GGPGVSPREGAQG-EGVRG 406
G A + RG G PG + GA G +G RG
Sbjct: 1053 GPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRG 1092
Score = 55.5 bits (132), Expect = 1e-07
Identities = 122/477 (25%), Positives = 147/477 (30%), Gaps = 137/477 (28%)
Query: 28 SQSESFDPSPRGRDGPWRH--VETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCE 85
SQ ES P P G GP V FP +G + A G+ R G
Sbjct: 556 SQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN-------------GERGGPGGP 602
Query: 86 APQTAPGFHFQPFLSLSPHQERG-RSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAA 144
PQ PG + E G + P P G +G TG P PQ L
Sbjct: 603 GPQGPPG----------KNGETGPQGPPGPTGPGGDKGDTGP----------PGPQGLQG 642
Query: 145 RRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSH 204
P PPG P GP + A PG G+ G P ++
Sbjct: 643 L-----PGTGGPPGENGKPGEPGP------KGDAGAPGAPGGKGDAGAPGERG------- 684
Query: 205 FLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLL 264
P G + P + P P P G+G A P G+A P L +
Sbjct: 685 ---PPGLAGA--PGLRGGAGP-PGPEG---------GKGAAGPPGPPGAAGTPGLQGM-- 727
Query: 265 ASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHG 324
P + LGS P G P P + R P G
Sbjct: 728 --------------PGERGGLGSPGPKGDKGEPGG---PGADGVPGKDGPRGPTGPIGPP 770
Query: 325 LPL--PRSLSRGGE-----VVGARRRRGGEERRVRGRRQGCALGSPPIPAG-PAAPGRAG 376
P P GG + G R G ER G PP PAG P APG+ G
Sbjct: 771 GPAGQPGDKGEGGAPGLPGIAGPRGSPG--ERGETG---------PPGPAGFPGAPGQNG 819
Query: 377 ERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQG-----GAP 431
E GG G G +GEG GV GS P P +G G P
Sbjct: 820 EP----------GGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGP 869
Query: 432 YRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATST 488
A F L P PG + P + S G+D P PA +T
Sbjct: 870 GAAGFPGARGLPGP-------PGSNGNPGPP--------GPSGSPGKDGPPGPAGNT 911
Score = 50.4 bits (119), Expect = 4e-06
Identities = 142/555 (25%), Positives = 172/555 (30%), Gaps = 135/555 (24%)
Query: 34 DPSPRGRDGPWRHVETFPRARGVEVASGRTRWTGPQPLVDTP--------PARRAGELCE 85
+P P+G G P A G + +G GP L P P G+
Sbjct: 658 EPGPKGDAGA-------PGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAA 710
Query: 86 APQTAPGFHFQPFLSLSPHQERGRSKPSP---------------PVSGTRRGKTG----- 125
P PG P L P + G P P P RG TG
Sbjct: 711 GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770
Query: 126 -----QWKEGRGSHP----TPEPQRLAARRWLHSPREPT----PPGRLSAPPRHGPHPQS 172
+G G P P+ R P P PG+ P G
Sbjct: 771 GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAP 830
Query: 173 FRRPSAHPPGRG---SGRVPRGQPEQQAWEQRSSHFLAP-----------------EGSV 212
+ PPG G P G P Q + P G+
Sbjct: 831 GEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNP 890
Query: 213 ASLLPSAKPARAPRPAPRAREEAAAGSRG----RGGAERPAARGS--AQQPPLARLLLAS 266
PS P + P P A A GS G +G A +P +GS AQ PP A L
Sbjct: 891 GPPGPSGSPGKDGPPGP-AGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949
Query: 267 AVSLAASLARSPPPLQPRLGSASPPRL--------AAPLAGSRAPSLSPFPRRCRRRA-- 316
A A PP + GS P + A L+G R P P P+ A
Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGP---PGPQGLPGLAGT 1006
Query: 317 ------ERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPA 370
+ +P GLP R S GG+ G R G G PP P GPA
Sbjct: 1007 AGEPGRDGNPGSDGLP-GRDGSPGGK--GDRGENGSP-----GAPGAPGHPGPPGPVGPA 1058
Query: 371 ----------------APGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRG-GVTPRAR 413
APG AG R A RG R A +G RG P A
Sbjct: 1059 GKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAP 1118
Query: 414 GSSTCLRPSPATWQG--GAPYRAIFAAGPR--LSAPSAEAEEVPGGHTASNPTYEPLSSR 469
GS P PA QG G+P AGPR + ++ GH P +R
Sbjct: 1119 GS-----PGPAGQQGAIGSP----GPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNR 1169
Query: 470 RTKAPSEGRDSPSSP 484
+ SEG SP P
Sbjct: 1170 GERG-SEG--SPGHP 1181
Score = 42.7 bits (99), Expect = 8e-04
Identities = 102/395 (25%), Positives = 128/395 (32%), Gaps = 55/395 (13%)
Query: 106 ERGRSKP----SPPVSGTRRGKTGQW--KEGRGSHPTPEPQRLAARRWLHSPR----EPT 155
E+G P PP G G K RGS P R L P P
Sbjct: 832 EKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPG 891
Query: 156 PPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASL 215
PPG +P + GP + + PG + GQP E+ S P G+ L
Sbjct: 892 PPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPG----EKGSPGAQGPPGAPGPL 947
Query: 216 ----LPSAKPARAPRPAPRAREEAAAGSRG-RGGAERPAARG-SAQQPPLARLLLASAVS 269
+ A+ P P R + G +G +G + +P A G S ++ P L
Sbjct: 948 GIAGITGARGLAGPPGMPGPR--GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAG 1005
Query: 270 LAASLARSPPP----LQPRLGS----------ASPPRLAAPLAGSRAPSLSPFPR-RCRR 314
A R P L R GS SP AP G P P +
Sbjct: 1006 TAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAP--GHPGPPGPVGPAGKSGD 1063
Query: 315 RAERSPAGH-GLPLPRSLSRGGEVVGARRRRGGEERR----VRGRRQGCALGSPPIPAGP 369
R E PAG G P P G R +G R ++G R G P P P
Sbjct: 1064 RGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHR-----GFPGNPGAP 1118
Query: 370 AAPGRAGERRAARQWRKRG-----GGPGVSPREGAQGE-GVRGGVTPRARGSSTCLRPSP 423
+PG AG++ A G G G ++G G G G PR SP
Sbjct: 1119 GSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSP 1178
Query: 424 ATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTA 458
P A GP A A GG A
Sbjct: 1179 GHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKA 1213
Score = 40.8 bits (94), Expect = 0.003
Identities = 94/378 (24%), Positives = 120/378 (31%), Gaps = 73/378 (19%)
Query: 157 PGRLSAPPRHGPH--PQSFRRP----SAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEG 210
PG AP GP P RP +A G R GQP P G
Sbjct: 290 PGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPG----------PPG 339
Query: 211 SVASL-LPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVS 269
+ P AK P +P + A G RG G P AQ PP + S
Sbjct: 340 TAGFPGSPGAKGEVGPAGSPGSN--GAPGQRGEPG---PQGHAGAQGPPGPPGINGSPGG 394
Query: 270 LAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGL---P 326
P +G+ PP P + AP L R P +G P
Sbjct: 395 KGEMGPAGIPGAPGLMGARGPP---GPAGANGAPGL--------RGGAGEPGKNGAKGEP 443
Query: 327 LPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRK 386
PR + G +G + + GSP P PG AGE R A +R
Sbjct: 444 GPRGERGEAGIPGVPGAKGEDGKD----------GSPGEPGANGLPGAAGE-RGAPGFRG 492
Query: 387 RGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQG--GAPYRAIFAAGPRLSA 444
G G+ +G GE RG+ P PA +G G P R GP +
Sbjct: 493 PAGPNGIPGEKGPAGE----------RGA-----PGPAGPRGAAGEPGRDGVPGGPGMRG 537
Query: 445 PSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHP 504
PGG + P S + P G PS P + G+ + P
Sbjct: 538 MPGS----PGGPGSDGKPGPPGSQGESGRP--GPPGPSGPRGQPGVMGFPGPKGN-DGAP 590
Query: 505 SRSPYNWSP--PSPSVPP 520
++ P P P PP
Sbjct: 591 GKNGERGGPGGPGPQGPP 608
>gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo
sapiens]
Length = 459
Score = 57.0 bits (136), Expect = 4e-08
Identities = 116/402 (28%), Positives = 148/402 (36%), Gaps = 109/402 (27%)
Query: 106 ERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREP---------TP 156
+ G +P+P + R K Q + GRG R AA L P EP TP
Sbjct: 49 DMGTLEPTPLL----RRKAAQLQPGRGKSCGA---RRAALPLLRYPPEPGVFPFLVLWTP 101
Query: 157 P---GRLSAPPRHGPHPQSF---RRPS----------------AHPPGRGSGRVPR--GQ 192
P GR+S P PQ+F R P+ P GRG GR R
Sbjct: 102 PFAPGRISPPA-----PQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAA 156
Query: 193 PEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEA--AAGSRGRGGAER--- 247
PE A S A GS +S + R+ R A + R A A G+ R ++
Sbjct: 157 PESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP 216
Query: 248 PAARGSAQQPPLARLLLA----------SAVSLA------ASLARSP----PPLQPRLGS 287
PA R A + P A LL+ +A S+A SL R P PP P++ +
Sbjct: 217 PAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPP--PQVLT 274
Query: 288 ASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHG---LPLPRSLSRGGEVVGARRRR 344
A P A P G R P P R R + PA G L L + RGG + RR
Sbjct: 275 AEPREDATPGEG-RLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVGRGGTGSWSWRRG 333
Query: 345 GGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRK-----RGGGPGVSPRE-- 397
G GC+ + A G++ E R R+ RGGG GV+ E
Sbjct: 334 AGS-----AELPGCSCAQ--LAQQLARAGKSTESRNRLNGRRGGVEARGGGGGVARAERD 386
Query: 398 ------GAQG-------------EGVRGGVTPRARGSSTCLR 420
G +G GVR G P RGSS R
Sbjct: 387 DVLQGLGLRGTEDWCARRAPRTSSGVRRGAAPGFRGSSNTAR 428
Score = 36.2 bits (82), Expect = 0.075
Identities = 62/233 (26%), Positives = 74/233 (31%), Gaps = 23/233 (9%)
Query: 274 LARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSR 333
L R LQP G + R AA P FP +P P P++
Sbjct: 59 LRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFL- 117
Query: 334 GGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGV 393
+ AR GG G+R+ PA G RR PG
Sbjct: 118 -AQRSPARASPGGGFTSAEGKRK----------TRPAGRGGGRTRRVVAAPESAAAAPGR 166
Query: 394 SPREGAQGEGVRGGVTPRARGSS-TCLRPSPATWQG-GAPYRAIFAAGPRLSAPSAEAEE 451
SP G PRAR SS L+P A GAP R+ A P AP A
Sbjct: 167 SPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP-PAPRFPASR 225
Query: 452 VPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHP 504
PG L SR + G +PS + L E G S P
Sbjct: 226 RPGA--------PRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPP 270
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 56.2 bits (134), Expect = 7e-08
Identities = 131/493 (26%), Positives = 172/493 (34%), Gaps = 94/493 (19%)
Query: 30 SESFDPSPRGRDGPWRH-VETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEA-P 87
S PS R D VE ++ + + G W P TPP +A P
Sbjct: 14 SRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWF---PGSATPPGLMVPREPQASP 70
Query: 88 QTAPGFHFQPFLSLSPHQERGR-SKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRL--AA 144
T P +P + P +E S P P +GT +W++ G+ P P +RL A+
Sbjct: 71 STLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGT-PVPRIRRLLEAS 129
Query: 145 RRWLHSP------REPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAW 198
R P + P PP +LS R PS PP + + P P ++
Sbjct: 130 HRGQGDPPSLRPLKPPPPPRQLSVKDTVP------RAPSQFPPPLETWKPPPPLPSER-- 181
Query: 199 EQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPP 258
Q + + P +L A P + PR + + A R RGGA A G QP
Sbjct: 182 -QPADRRITP-----ALATPASPPTESQAGPRNQGQTAG--RARGGAPPHAGEGEMAQPA 233
Query: 259 --------LARLLLASAVSLAASLARSPPPLQPRLGSASPPRL-AAPLAGSRAPSLSPFP 309
L ++ S SLA A S + LG L AA A S A L P
Sbjct: 234 DSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGP 293
Query: 310 RRCRRRAERSPAGHGLPLPRSLSRGGEVV-GARRRRGGEERRVRGRRQGCALGSPPIPAG 368
P G PL GEV GA+ GG+ G +GC+ G P PA
Sbjct: 294 ---------LPPGAARPL-------GEVSRGAQEAEGGD-----GDGEGCS-GPPSAPAS 331
Query: 369 PAA----------PGRA----------GERRAARQWRKRGGGPGVSPREGAQGEGVRGGV 408
A PG G R R + GGG G R A G G
Sbjct: 332 QARALPPPPYTTFPGSKPKFDWVSAPDGPERHFR-FNGAGGGIGAPRRRAAALSGPWGSP 390
Query: 409 TP---RARGSSTCLRPSPATWQGGAPYRAIFAA----GPRLSAPSAEAEEVPGGHTASNP 461
P + + RP+PA AP IF A P P E P P
Sbjct: 391 PPPPEQIHSAPGPRRPAPALL---APPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPP 447
Query: 462 TYEPLSSRRTKAP 474
T +P + + T P
Sbjct: 448 TLQPPALQPTPLP 460
Score = 35.8 bits (81), Expect = 0.097
Identities = 90/336 (26%), Positives = 110/336 (32%), Gaps = 63/336 (18%)
Query: 108 GRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGR------LS 161
G ++P VS + G +G G P AR L P T PG +S
Sbjct: 297 GAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARA-LPPPPYTTFPGSKPKFDWVS 355
Query: 162 APPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVA---SLLPS 218
AP GP + FR A G G G PR +R++ P GS + S
Sbjct: 356 APD--GPE-RHFRFNGA---GGGIG-APR---------RRAAALSGPWGSPPPPPEQIHS 399
Query: 219 AKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLL--------------L 264
A R P PA A + G RP G + PPL L
Sbjct: 400 APGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPL 459
Query: 265 ASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHG 324
A L L L P A PP LAA +AP+ SP P AE SP
Sbjct: 460 PVAPPLTPGLGHKESALAPTAAPALPPALAA----DQAPAPSPAP--APTVAEPSPP-VS 512
Query: 325 LPLPRSLSRGGEVVGARRRRGGEERRVRG--RRQGCALGSPPIPAGPAAPGRAGERRAAR 382
P P + + R RR R RG R+ G P A P +G
Sbjct: 513 APAPAAAP-----IKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSG------ 561
Query: 383 QWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTC 418
GGG G S A R + + S C
Sbjct: 562 ---GGGGGSGASQTGAANTRAARHWLPFQVLNSCPC 594
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 55.8 bits (133), Expect = 9e-08
Identities = 111/451 (24%), Positives = 144/451 (31%), Gaps = 71/451 (15%)
Query: 111 KPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLS-----APPR 165
KP P+ R + P P+P W P PP S APP
Sbjct: 621 KPGTPIVLRRAQPRARSSNDARRPPAPQPAPRTLSHWSALLSPPVPPRPPSSGPPPAPPL 680
Query: 166 HGPHPQSFRRPSA-------HPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPS 218
P RP++ HPP + P+ W F+ P + P
Sbjct: 681 -SPALSGLPRPASPYGSLRRHPPPWAAPAHVPPAPQASWWA-----FVEPPAVSPEVPPD 734
Query: 219 AKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQP---PLARLLLASAVSLAASLA 275
PRP+ R A + G GA A+R A P P L + + + LA
Sbjct: 735 LLAFPGPRPSFRGSRRRGA-AFGFPGASPRASRRRAWSPLASPQPSLRSSPGLGYCSPLA 793
Query: 276 RSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGG 335
P L R G PP L P R+ SP PRR R G PLP S
Sbjct: 794 PPSPQLSLRTGPFQPPFL-PPARRPRSLQESPAPRRAAGRL----GPPGSPLPGSPRPPS 848
Query: 336 EVVGA--RRRRGGEERRVRGRRQGCALGSPPIPAGPA-------APGRAGERRAARQWRK 386
+G RR R L PP A P RAG RA + R+
Sbjct: 849 PPLGLCHSPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAWRAPLEHRE 908
Query: 387 RGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPS---PATWQGGAPYRAIFAAGP--- 440
SPRE E V P A + P+ P+ W GGA R F+ P
Sbjct: 909 -------SPREPEDSE-TPWTVPPLAPSWDVDMPPTQRPPSPWPGGAGSRRGFSRPPPVP 960
Query: 441 ---------RLSAPSAEAEEVPGGHTA--SNPTYEPLSSRRTKAPSEGRDSPSSPATSTH 489
+ +P+ + E+ T +EP + TK+ + P AT
Sbjct: 961 ENPFLQLLGPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKSAGPTPEKPEEEAT--- 1017
Query: 490 YLDRESGLGSVNSHPSRSPYNWSPPSPSVPP 520
LG P +PP PP
Sbjct: 1018 -------LGDPQLPAETKPPTPAPPKDVTPP 1041
Score = 39.7 bits (91), Expect = 0.007
Identities = 69/266 (25%), Positives = 85/266 (31%), Gaps = 67/266 (25%)
Query: 66 TGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGR-SKPSPPVSGTRRGKT 124
TGP PPARR L E+P +P + GR P P+ G+ R
Sbjct: 803 TGPFQPPFLPPARRPRSLQESP--------------APRRAAGRLGPPGSPLPGSPR--- 845
Query: 125 GQWKEGRGSHPTPEPQRLAARRWLHSPRE---------PTPPGRLSAPPRHGPHPQSFRR 175
P P L HSPR P RLS PP PQ R
Sbjct: 846 ----------PPSPPLGLC-----HSPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQ-VRL 889
Query: 176 PSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEA 235
P PP G+ R P E + S +V L PS P P +
Sbjct: 890 PFHRPPRAGAWRAPLEHRESPREPEDSE----TPWTVPPLAPSWDVDMPPTQRPPSPWPG 945
Query: 236 AAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRL-- 293
AGSR RG ++ PP+ + S P LQP +A R+
Sbjct: 946 GAGSR----------RGFSRPPPVPENPFLQLLGPVPS-----PTLQPEDPAADMTRVFL 990
Query: 294 ---AAPLAGSRAPSLSPFPRRCRRRA 316
P G S P P + A
Sbjct: 991 GRHHEPGPGQLTKSAGPTPEKPEEEA 1016
Score = 31.6 bits (70), Expect = 1.8
Identities = 91/376 (24%), Positives = 128/376 (34%), Gaps = 76/376 (20%)
Query: 5 WGQRKVPMTRRASPVFTGFCVNTSQSESFDPSPRG--RDGPWRHVETFP--RARGVEVAS 60
W P S G+C S PSP+ R GP++ P R R ++ +
Sbjct: 770 WSPLASPQPSLRSSPGLGYC-----SPLAPPSPQLSLRTGPFQPPFLPPARRPRSLQESP 824
Query: 61 GRTRWTG-------PQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRS--- 110
R G P P PP+ G LC +P+ + S PH R S
Sbjct: 825 APRRAAGRLGPPGSPLPGSPRPPSPPLG-LCHSPRRSS----LNLPSRLPHTWRRLSEPP 879
Query: 111 ----KPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRH 166
KP + R + G W+ +P + W P P+ + PP
Sbjct: 880 TRAVKPQVRLPFHRPPRAGAWRAPLEHRESPREPEDSETPWTVPPLAPS--WDVDMPPTQ 937
Query: 167 GPHPQSFRRPSAHPPGRGSGR-------VPRGQPEQQAWEQRSSHFLAPEGSVASLLP-- 217
P PS P G GS R VP P Q S L PE A +
Sbjct: 938 RP-------PSPWPGGAGSRRGFSRPPPVPEN-PFLQLLGPVPSPTLQPEDPAADMTRVF 989
Query: 218 --------SAKPARAPRPAP-RAREEAAAGSRGRGGAERPAARGSAQQ--PPL----ARL 262
+ ++ P P + EEA G +P + PP +
Sbjct: 990 LGRHHEPGPGQLTKSAGPTPEKPEEEATLGDPQLPAETKPPTPAPPKDVTPPKDITPPKD 1049
Query: 263 LLASAVSLAASLA---------RSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCR 313
+L +L SL+ R+ P R G+ P+ AAPLA RAP P P+
Sbjct: 1050 VLPEQKTLRPSLSYPLAACDQTRATWPPWHRWGTL--PQAAAPLAPIRAP--EPLPKGGE 1105
Query: 314 RRAERSPAGHGLPLPR 329
RR + +P + +PR
Sbjct: 1106 RR-QAAPGRFAVVMPR 1120
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 55.8 bits (133), Expect = 9e-08
Identities = 110/436 (25%), Positives = 148/436 (33%), Gaps = 65/436 (14%)
Query: 99 LSLSPHQERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEP---------QRLAARRWLH 149
L+ +P +E KP VS R +GQ P P P R R H
Sbjct: 255 LTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQH 314
Query: 150 S------------PREPTPPGRLSAPPRHGPHPQSFRR-----PSAHPP------GRGSG 186
S P E P R + P P R P PP G+ G
Sbjct: 315 SSALTASVEEGGVPGE-DPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDG 373
Query: 187 RVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKP---ARAPRPAPRAREEAAAGSRGRG 243
P P A ++ APE VAS P+A P P P A EA + R
Sbjct: 374 EAPPAGPCAPATDKAEEVVCAPE-DVASPFPTAIPEGDTTPPETDPAATSEAPS---ARD 429
Query: 244 GAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAP 303
G ER + + PP+ A R R P R+ + + AP
Sbjct: 430 GPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAP 489
Query: 304 SLSPFPRRC-RRRAERSPAGHGLPLPRSLSRGGEV---VGARRRRGGEERRVRGRRQGCA 359
S P P+ C + R + G P + + V G+ R + R
Sbjct: 490 S-PPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAER---- 544
Query: 360 LGSPPIPAGPAAPGRAGER-----RAARQWR----KRGGGPGVS-PREGAQGE--GVRGG 407
+PP A AAP R ER R A+++ + PGVS P E A G R G
Sbjct: 545 AEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSG 604
Query: 408 VTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLS----APSAEAEEVPGGHTASNPTY 463
R+ + L+ P R + GP+ S A A + P A+ T
Sbjct: 605 PVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTR 664
Query: 464 EPLSSRRTKAPSEGRD 479
EP + + APSE R+
Sbjct: 665 EPCPAAQEPAPSEDRN 680
Score = 45.4 bits (106), Expect = 1e-04
Identities = 95/357 (26%), Positives = 134/357 (37%), Gaps = 68/357 (19%)
Query: 74 TPPARRAGELCEAPQTAPG------FHFQPFLSLSPHQERGRSKPSPPVSGTRRGKTGQW 127
TPP EAP G +P + P +E+G P+P R +T +
Sbjct: 412 TPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPE--REAET-EP 468
Query: 128 KEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGR 187
+ G G+ EP+R+ + P+PP S +H P S P+A PP +
Sbjct: 469 ERGAGT----EPERIGTEP--STAPAPSPPAPKSCL-KHRPAAAS-EGPAASPP-LAAAE 519
Query: 188 VPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREE------------- 234
P +P + + ++ APE A A PA A R AP + E
Sbjct: 520 SPPVEPGPGSLDAEAA---APERPKAERA-EAPPAGAERAAPERKAERGGAELRGAKKFS 575
Query: 235 -AAAGSRGRGGAERPAARGSAQQPPLAR--------LLLASAVSLAASLARSPPP--LQP 283
++ +R R G RP R S + P LAR L L P P L
Sbjct: 576 VSSCRARPRPGVSRPLERASGRLP-LARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAE 634
Query: 284 RLGSASPPRLAAPLAGSRAP---SLSPFPRR-CRRRAERSPAGHGLPLP---RSLS---- 332
R S R A+P ++P + +P R C E +P+ P P RS S
Sbjct: 635 RGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLK 694
Query: 333 -RGG---EVVGARRRRGGEERRVRG-----RRQGCALGSPPIPAGPAAPGRAGERRA 380
R G EV G +R E R R + + C LG+ P G AP G+ +A
Sbjct: 695 YRDGASQEVKGVKRY-SAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKA 750
Score = 39.7 bits (91), Expect = 0.007
Identities = 84/325 (25%), Positives = 114/325 (35%), Gaps = 77/325 (23%)
Query: 53 ARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLS-LSPHQERGRSK 111
A+ V+S R R P+P V P R +G L A ++ P + + L L E +K
Sbjct: 571 AKKFSVSSCRAR---PRPGVSRPLERASGRLPLA-RSGPVWRSEAALDDLQGLPEPQHAK 626
Query: 112 PSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPR-HGPHP 170
P P R + + + P PQ AA REP P + AP P P
Sbjct: 627 PGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAP---GTREPCPAAQEPAPSEDRNPFP 683
Query: 171 QSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPR-PAP 229
R S S + G ++ +R S + E S+ ++LP K + P AP
Sbjct: 684 VKLRSTSL------SLKYRDGASQEVKGVKRYSAEVRLERSL-TVLP--KEEKCPLGTAP 734
Query: 230 RAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSAS 289
R A +G+G A P S +PPL R L + +L P QP A
Sbjct: 735 ALRGTRAPSDQGKGKARPPEPLSS--KPPLPRKPLLQSFTL---------PHQPAPPDAG 783
Query: 290 PPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEER 349
P G R P P R AE+ P RRG E+
Sbjct: 784 P--------GEREPRKEP------RTAEKRPL---------------------RRGAEK- 807
Query: 350 RVRGRRQGCALGSPPIPAGPAAPGR 374
PP GP A G+
Sbjct: 808 -----------SLPPAATGPGADGQ 821
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 55.5 bits (132), Expect = 1e-07
Identities = 126/507 (24%), Positives = 169/507 (33%), Gaps = 101/507 (19%)
Query: 48 ETFPRARGVEVASGRTRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQER 107
+TF A G++ A GR P+ L + P+ R L EA G P +P
Sbjct: 512 DTFTSA-GLDPA-GRCLLPRPKSLAGSCPSTRLLTLEEAQARTQGRLGTPTEPTTPKAPA 569
Query: 108 GRSKPSPPVSGTRRGKTG--QWKE----GRGSHPTPEPQRLAARRWLHSPREPTPPGRLS 161
++ G ++ K G WK GRG P R WL R P P
Sbjct: 570 SPAERRKGERGEKQRKPGGSSWKTFFALGRG----PSVPRKKPLPWLGGTRAPPQPS--- 622
Query: 162 APPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSA-- 219
G P + SA E + + + L G+ AS P+
Sbjct: 623 -----GSRPDTVTLRSAK------------SEESLSSQASGAELLGAGGAPASATPTPAL 665
Query: 220 KPARAPRP-----------AP---RAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLA 265
P R+ RP AP ++E + RG G P PPL+ L
Sbjct: 666 SPGRSLRPHLIPLLLRGAEAPLTDACQQEMCSKLRGAQGPLGPDMESPLPPPPLSLLRPG 725
Query: 266 SAVSLAASLARSPPPLQP-RLGSASPPRLAAPLA---------GSRAPSLSPFPRRCRRR 315
A PPP P RL + + A +A G+ S SPF R
Sbjct: 726 GAPP--------PPPKNPARLMALALAERAQQVAEQQSQQECGGTPPASQSPFHRSLSLE 777
Query: 316 AERSPAGHGL--PLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPG 373
P G P P SL+ G V G R + G L S P G + G
Sbjct: 778 VGGEPLGTSGSGPPPNSLAHPGAWVP-----GPPPYLPRQQSDGSLLRSQR-PMGTSRRG 831
Query: 374 RAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYR 433
G + + Q R GGG P A S C PS P
Sbjct: 832 LRGPAQVSAQLRAGGGGRDA----------------PEAAAQSPCSVPSQV------PTP 869
Query: 434 AIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDR 493
F+ PR P PG + P+++P S S G +P + +Y +
Sbjct: 870 GFFSPAPRECLPPFLGVPKPGLYPLGPPSFQPSSPAPVWRSSLGPPAPLDRGENLYY-EI 928
Query: 494 ESGLGSVNSHPSRSPYNWSPPSPSVPP 520
+ GS S P+RS WS P S+PP
Sbjct: 929 GASEGSPYSGPTRS---WS-PFRSMPP 951
Score = 38.9 bits (89), Expect = 0.012
Identities = 57/189 (30%), Positives = 71/189 (37%), Gaps = 30/189 (15%)
Query: 86 APQTAPGFHFQPFLSLSPHQ---ERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPE---P 139
+P + P + PF S+ P + G SPP+ + P P P
Sbjct: 934 SPYSGPTRSWSPFRSMPPDRLNASYGMLGQSPPLHRSPDFLLSY-------PPAPSCFPP 986
Query: 140 QRLAARRWLHSPREPTPPG----RLSAPPRHGPHP--QSFRRPSAHPPGRG--SGRVPRG 191
L H R PTPP L+ PR GP P S P AHP R VPR
Sbjct: 987 DHLGYSAPQHPARRPTPPEPLYVNLALGPR-GPSPASSSSSSPPAHPRSRSDPGPPVPRL 1045
Query: 192 QPEQQA-WEQRSSHFL-APEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPA 249
+Q+A W R+ H + P G LL RA PA E GS R G +R
Sbjct: 1046 PQKQRAPWGPRTPHRVPGPWGPPEPLL----LYRAAPPAYGRGGELHRGSLYRNGGQR-- 1099
Query: 250 ARGSAQQPP 258
G+ PP
Sbjct: 1100 GEGAGPPPP 1108
Score = 35.8 bits (81), Expect = 0.097
Identities = 83/326 (25%), Positives = 106/326 (32%), Gaps = 85/326 (26%)
Query: 115 PVSGTRRGKTG------QWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGP 168
P+ +RRG G Q + G G PE AA+ P + PG S PR
Sbjct: 824 PMGTSRRGLRGPAQVSAQLRAGGGGRDAPEA---AAQSPCSVPSQVPTPGFFSPAPRECL 880
Query: 169 HP-QSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSS---------------HFLAPEGSV 212
P +P +P G P QP A RSS A EGS
Sbjct: 881 PPFLGVPKPGLYPLGP-----PSFQPSSPAPVWRSSLGPPAPLDRGENLYYEIGASEGS- 934
Query: 213 ASLLPSAKPARAPRP---APRAREEAAAGSRGRG-------------------------- 243
P + P R+ P P R A+ G G+
Sbjct: 935 ----PYSGPTRSWSPFRSMPPDRLNASYGMLGQSPPLHRSPDFLLSYPPAPSCFPPDHLG 990
Query: 244 --GAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSR 301
+ PA R + +P L L AS + S PP PR S P + R
Sbjct: 991 YSAPQHPARRPTPPEPLYVNLALGPRGPSPASSSSSSPPAHPRSRSDPGPPVPRLPQKQR 1050
Query: 302 APSLSPFPRRCRRRAERSPAGHGLPL------PRSLSRGGEV-VGARRRRGGEERRVRGR 354
AP P R P G PL P + RGGE+ G+ R GG+ RG
Sbjct: 1051 APWGPRTPHRV-----PGPWGPPEPLLLYRAAPPAYGRGGELHRGSLYRNGGQ----RGE 1101
Query: 355 RQGCALGSPPIPAGPAAPGRAGERRA 380
G PP P + G+ R+
Sbjct: 1102 GAG---PPPPYPTPSWSLHSEGQTRS 1124
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 55.1 bits (131), Expect = 2e-07
Identities = 91/333 (27%), Positives = 115/333 (34%), Gaps = 68/333 (20%)
Query: 158 GRLSAPPRHGPHPQSFRRPSAHPPGR-GSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLL 216
G LS P P P + + P AH G G+ P G+P AP +
Sbjct: 240 GGLSPEPPEPPPPAA-KGPGAHASGAAGTAPAPPGEPP------------APGTCDPAFY 286
Query: 217 PSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLAR 276
PS + P+P P + A S G G A RG+A P AS S+ + L+
Sbjct: 287 PSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPK------ASPFSVESLLSD 340
Query: 277 SPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGE 336
SP PR +AS AA AP L PR + GH L P + G
Sbjct: 341 SP----PRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGK------GHFLLYPITQPLGFL 390
Query: 337 VVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPR 396
V A + G + +PP PA P AP A GPG +P
Sbjct: 391 VPQAALKGG-------AGLEPAPKDAPPAPAVPPAPPAQASFGAF-------SGPGGAPD 436
Query: 397 EGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGH 456
+P A P+PA AP+R + SA A E GG
Sbjct: 437 SAFARRSPDAVASPGA--------PAPAP----APFRDL---------ASAAATEGGGGD 475
Query: 457 TASNPTYEPLSSRRTKAPSEGRDSPS---SPAT 486
A T P +P G PS PAT
Sbjct: 476 CADAGTAGPAPPPPAPSPRPGPRPPSPAEEPAT 508
Score = 33.1 bits (74), Expect = 0.63
Identities = 67/244 (27%), Positives = 80/244 (32%), Gaps = 52/244 (21%)
Query: 28 SQSESFDPSPR-GRDGPWRHVETFPRARGVEVASGRTRWTGPQP------LVDTPPARRA 80
SQ P PR GR P A V G P L D+PP R+A
Sbjct: 288 SQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKA 347
Query: 81 GELCEAPQTAPGFHFQPFLSLSPHQERGRSK----PSPPVSGTRRGKTGQWKEGRGSHPT 136
A A G F P L +P G+ P G + K G G P
Sbjct: 348 ASNAAAAAAA-GLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAA-LKGGAGLEPA 405
Query: 137 PEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQ 196
P+ +P P P APP SF G SG P G P+
Sbjct: 406 PK----------DAPPAPAVP---PAPPAQA----SF--------GAFSG--PGGAPD-S 437
Query: 197 AWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQ 256
A+ +RS +A G A AP PAP +AA + G GG A
Sbjct: 438 AFARRSPDAVASPG-----------APAPAPAPFRDLASAAATEGGGGDCADAGTAGPAP 486
Query: 257 PPLA 260
PP A
Sbjct: 487 PPPA 490
Score = 32.7 bits (73), Expect = 0.82
Identities = 42/136 (30%), Positives = 51/136 (37%), Gaps = 15/136 (11%)
Query: 205 FLAPEGSV---ASLLPSAK---PARAPRPAPRAREEAAAGSRGRGGA-------ERPAAR 251
FL P+ ++ A L P+ K PA A PAP A+ A S G GGA P A
Sbjct: 389 FLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFS-GPGGAPDSAFARRSPDAV 447
Query: 252 GSAQQPPLARLLLASAVSLAASLARSPPPLQP-RLGSASPPRLAAPLAGSRAPSLSPFPR 310
S P A S AA+ G A PP +P G R PS + P
Sbjct: 448 ASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPA 507
Query: 311 RCRRRAERSPAGHGLP 326
C + AG P
Sbjct: 508 TCGVPEPGAAAGPSPP 523
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 54.7 bits (130), Expect = 2e-07
Identities = 69/257 (26%), Positives = 86/257 (33%), Gaps = 58/257 (22%)
Query: 63 TRWTGPQPLVDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGTRRG 122
T TG + PP G AP T H S R KP PP G R
Sbjct: 165 TSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHS------SKAPAYNREKPLPPTPGQRL- 217
Query: 123 KTGQWKEGRGSHPTPEPQRLAARRWLHSPREPT-----PPGRLSAPPRHGPHPQSFRRPS 177
GR P P P + P P P G+ APP P +R+P
Sbjct: 218 -----HPGREGPPAPPPVK--------PPPSPVNIRTGPSGQSLAPP-----PPPYRQPP 259
Query: 178 AHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAP-----RPAPRAR 232
P G S P + + ++ +S G V L P + +P RP P AR
Sbjct: 260 GVPNGPSS---PTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPAR 316
Query: 233 EEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPPR 292
+ P +RG+A PP + A A PPP GS P R
Sbjct: 317 D--------------PPSRGAAPPPP------PPVIRNGARDAPPPPPPYRMHGSEPPSR 356
Query: 293 LAAPLAGSRAPSLSPFP 309
P SR P+ P P
Sbjct: 357 GKPPPPPSRTPAGPPPP 373
Score = 40.8 bits (94), Expect = 0.003
Identities = 76/331 (22%), Positives = 112/331 (33%), Gaps = 82/331 (24%)
Query: 210 GSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQ---------PPLA 260
G A +PS++ A APRP A + GR + ++R S + P L+
Sbjct: 109 GKPALQIPSSRAA-APRPPVSA-------ASGRPQDDTDSSRASLPELPRMQRPSLPDLS 160
Query: 261 RLLLASAVSLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLS---PFPRRCRRRAE 317
R S+ + S + PPP R +A P L P+ S+AP+ + P P +R
Sbjct: 161 RPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPL--PMHSSKAPAYNREKPLPPTPGQRLH 218
Query: 318 RSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPP--------IPAGP 369
P G P P + V R G+ +L PP +P GP
Sbjct: 219 --PGREGPPAPPPVKPPPSPVNIRTGPSGQ-----------SLAPPPPPYRQPPGVPNGP 265
Query: 370 AAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGG 429
++P P + R + G V A T PS + +
Sbjct: 266 SSPTNES-------------APELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPP 312
Query: 430 APYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTH 489
P R + G +AP + G + P P ++ PS G+ P
Sbjct: 313 PPARDPPSRG---AAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPP------- 362
Query: 490 YLDRESGLGSVNSHPSRSPYNWSPPSPSVPP 520
PSR+P PP P PP
Sbjct: 363 --------------PSRTPA--GPPPPPPPP 377
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 54.3 bits (129), Expect = 3e-07
Identities = 99/382 (25%), Positives = 123/382 (32%), Gaps = 68/382 (17%)
Query: 61 GRTRWTGPQPLVDTPPARRAGELCEAPQ--TAPGFHFQPFLSLSPHQERGRSKPSPPVSG 118
GR GP+ + G P+ T G P L + P PP
Sbjct: 554 GRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARS 613
Query: 119 TRRGKTGQWKEGRG---SHPTPEPQ----RLAARRWLHSPREPTPPGRLSAPPRHGPHPQ 171
+ G G G P P+P R L E PP S+ P GP P
Sbjct: 614 PSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTE-RPPKLCSSLPGQGPPPY 672
Query: 172 SFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRA 231
F P P G P G P W + +LA P A P PRP R+
Sbjct: 673 VFMYPQGSPSSPAPG-PPPGAP----W---AFSYLAG--------PPATPPDPPRPKRRS 716
Query: 232 REEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPP 291
S R G A G A+ P + S + A+L R P + L SP
Sbjct: 717 H------SLSRPGPTEGDAEGEAEGP------VGSTLGSYATLTRRPG--RSALVRTSPS 762
Query: 292 RLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGL-------PLPRSLSRGGEVVGARRRR 344
P G+ P F R RR+ P L P P L E G +
Sbjct: 763 VTPTPARGT--PRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLD---ESPGPKEGA 817
Query: 345 GGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGV 404
G RR G + PP P PA P E + G G P G+ GEG+
Sbjct: 818 TGPRRRTLSEPAGPS--EPPGPPAPAGPASDTE-------EEEPGPEGTPPSRGSSGEGL 868
Query: 405 RGGVTPRARGSSTCL--RPSPA 424
P A + + RP PA
Sbjct: 869 -----PFAEEGNLTIKQRPKPA 885
Score = 43.5 bits (101), Expect = 5e-04
Identities = 72/317 (22%), Positives = 100/317 (31%), Gaps = 68/317 (21%)
Query: 68 PQPLVDTP--------PARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGT 119
P PL ++P P RR P PG P P + +P P +
Sbjct: 804 PPPLDESPGPKEGATGPRRRTLSEPAGPSEPPG----PPAPAGPASDTEEEEPGPEGTPP 859
Query: 120 RRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSF------ 173
RG +G+ P E L ++ P P G PPR P P
Sbjct: 860 SRGSSGE------GLPFAEEGNLTIKQ------RPKPAG---PPPRETPVPPGLDFNLTE 904
Query: 174 -----RRPSAHP-----------------PGRGS---GRVPRGQPEQQAWEQRSSHFLAP 208
RRP PG + P P + Q L
Sbjct: 905 SDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPA 964
Query: 209 EGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAV 268
+G L PS P P E++A SR G E PAA + + P A
Sbjct: 965 QGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVS 1024
Query: 269 SLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLP 328
LA S P L PRLG P G+ P + ++R E++ + L
Sbjct: 1025 VACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPG------QAQQRLEQTSSS----LA 1074
Query: 329 RSLSRGGEVVGARRRRG 345
+L + +G + + G
Sbjct: 1075 AALRAAEKSIGTKEQEG 1091
Score = 30.0 bits (66), Expect = 5.3
Identities = 59/240 (24%), Positives = 76/240 (31%), Gaps = 58/240 (24%)
Query: 278 PPPLQPRL----GSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSR 333
P PRL GS P L A +AG P P LPLP + S
Sbjct: 575 PATAGPRLLTFQGSELSPELQAAMAGG-----GPEP---------------LPLPPARSP 614
Query: 334 GGEVVGARRRRGGEERRVRGRRQGCALGSPP----IPAGPAAPGRAGERRAARQWRKRGG 389
E +GAR R G + + SPP +P G P
Sbjct: 615 SQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERP----------------- 657
Query: 390 GPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEA 449
P + QG + P+ SS P P GAP+ + AGP + P
Sbjct: 658 -PKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPP-----GAPWAFSYLAGPPATPPDPPR 711
Query: 450 EEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGS-VNSHPSRSP 508
+ H+ S P A E S S L R G + V + PS +P
Sbjct: 712 PK-RRSHSLSRP-----GPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTP 765
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 54.3 bits (129), Expect = 3e-07
Identities = 99/382 (25%), Positives = 123/382 (32%), Gaps = 68/382 (17%)
Query: 61 GRTRWTGPQPLVDTPPARRAGELCEAPQ--TAPGFHFQPFLSLSPHQERGRSKPSPPVSG 118
GR GP+ + G P+ T G P L + P PP
Sbjct: 636 GRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARS 695
Query: 119 TRRGKTGQWKEGRG---SHPTPEPQ----RLAARRWLHSPREPTPPGRLSAPPRHGPHPQ 171
+ G G G P P+P R L E PP S+ P GP P
Sbjct: 696 PSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTE-RPPKLCSSLPGQGPPPY 754
Query: 172 SFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRA 231
F P P G P G P W + +LA P A P PRP R+
Sbjct: 755 VFMYPQGSPSSPAPG-PPPGAP----W---AFSYLAG--------PPATPPDPPRPKRRS 798
Query: 232 REEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSASPP 291
S R G A G A+ P + S + A+L R P + L SP
Sbjct: 799 H------SLSRPGPTEGDAEGEAEGP------VGSTLGSYATLTRRPG--RSALVRTSPS 844
Query: 292 RLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGL-------PLPRSLSRGGEVVGARRRR 344
P G+ P F R RR+ P L P P L E G +
Sbjct: 845 VTPTPARGT--PRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLD---ESPGPKEGA 899
Query: 345 GGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQGEGV 404
G RR G + PP P PA P E + G G P G+ GEG+
Sbjct: 900 TGPRRRTLSEPAGPS--EPPGPPAPAGPASDTE-------EEEPGPEGTPPSRGSSGEGL 950
Query: 405 RGGVTPRARGSSTCL--RPSPA 424
P A + + RP PA
Sbjct: 951 -----PFAEEGNLTIKQRPKPA 967
Score = 43.5 bits (101), Expect = 5e-04
Identities = 72/317 (22%), Positives = 100/317 (31%), Gaps = 68/317 (21%)
Query: 68 PQPLVDTP--------PARRAGELCEAPQTAPGFHFQPFLSLSPHQERGRSKPSPPVSGT 119
P PL ++P P RR P PG P P + +P P +
Sbjct: 886 PPPLDESPGPKEGATGPRRRTLSEPAGPSEPPG----PPAPAGPASDTEEEEPGPEGTPP 941
Query: 120 RRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPHPQSF------ 173
RG +G+ P E L ++ P P G PPR P P
Sbjct: 942 SRGSSGE------GLPFAEEGNLTIKQ------RPKPAG---PPPRETPVPPGLDFNLTE 986
Query: 174 -----RRPSAHP-----------------PGRGS---GRVPRGQPEQQAWEQRSSHFLAP 208
RRP PG + P P + Q L
Sbjct: 987 SDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPA 1046
Query: 209 EGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAV 268
+G L PS P P E++A SR G E PAA + + P A
Sbjct: 1047 QGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVS 1106
Query: 269 SLAASLARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLP 328
LA S P L PRLG P G+ P + ++R E++ + L
Sbjct: 1107 VACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPG------QAQQRLEQTSSS----LA 1156
Query: 329 RSLSRGGEVVGARRRRG 345
+L + +G + + G
Sbjct: 1157 AALRAAEKSIGTKEQEG 1173
Score = 30.0 bits (66), Expect = 5.3
Identities = 59/240 (24%), Positives = 76/240 (31%), Gaps = 58/240 (24%)
Query: 278 PPPLQPRL----GSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSR 333
P PRL GS P L A +AG P P LPLP + S
Sbjct: 657 PATAGPRLLTFQGSELSPELQAAMAGG-----GPEP---------------LPLPPARSP 696
Query: 334 GGEVVGARRRRGGEERRVRGRRQGCALGSPP----IPAGPAAPGRAGERRAARQWRKRGG 389
E +GAR R G + + SPP +P G P
Sbjct: 697 SQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERP----------------- 739
Query: 390 GPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEA 449
P + QG + P+ SS P P GAP+ + AGP + P
Sbjct: 740 -PKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPP-----GAPWAFSYLAGPPATPPDPPR 793
Query: 450 EEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGS-VNSHPSRSP 508
+ H+ S P A E S S L R G + V + PS +P
Sbjct: 794 PK-RRSHSLSRP-----GPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTP 847
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,345,924
Number of Sequences: 37866
Number of extensions: 2221543
Number of successful extensions: 16679
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 2103
Number of HSP's that attempted gapping in prelim test: 10862
Number of HSP's gapped (non-prelim): 6409
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.