BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|110618240 CD1E antigen isoform a precursor [Homo sapiens] (388 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|110618240 CD1E antigen isoform a precursor [Homo sapiens] 804 0.0 gi|110618230 CD1E antigen isoform b precursor [Homo sapiens] 770 0.0 gi|110618234 CD1E antigen isoform d precursor [Homo sapiens] 603 e-173 gi|110618232 CD1E antigen isoform c precursor [Homo sapiens] 562 e-160 gi|4502649 CD1D antigen precursor [Homo sapiens] 363 e-100 gi|4502645 CD1B antigen precursor [Homo sapiens] 358 5e-99 gi|110618224 CD1A antigen precursor [Homo sapiens] 357 1e-98 gi|110618236 CD1E antigen isoform e precursor [Homo sapiens] 345 3e-95 gi|110618227 CD1C antigen precursor [Homo sapiens] 345 3e-95 gi|110618238 CD1E antigen isoform f precursor [Homo sapiens] 137 1e-32 gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 74 3e-13 gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 74 3e-13 gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 66 5e-11 gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 65 1e-10 gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 65 1e-10 gi|4504417 major histocompatibility complex, class I-related [Ho... 64 2e-10 gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 63 5e-10 gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 62 7e-10 gi|149158702 major histocompatibility complex, class I, F isofor... 61 2e-09 gi|149158698 major histocompatibility complex, class I, F isofor... 61 2e-09 gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 61 2e-09 gi|4504415 major histocompatibility complex, class I, G precurso... 61 2e-09 gi|24797067 major histocompatibility complex, class I, A precurs... 61 2e-09 gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 60 4e-09 gi|52630342 major histocompatibility complex, class I, C precurs... 58 2e-08 gi|17986001 major histocompatibility complex, class I, B precurs... 54 2e-07 gi|24797076 major histocompatibility complex, class II, DP beta ... 52 7e-07 gi|62912479 major histocompatibility complex, class I, E precurs... 50 3e-06 gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 49 8e-06 gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 49 8e-06 >gi|110618240 CD1E antigen isoform a precursor [Homo sapiens] Length = 388 Score = 804 bits (2076), Expect = 0.0 Identities = 388/388 (100%), Positives = 388/388 (100%) Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60 Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120 Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180 Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240 Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH Sbjct: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300 Query: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS Sbjct: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360 Query: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388 RHQFCLAQVSWIKNRVLKKWKTRLNQLW Sbjct: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388 >gi|110618230 CD1E antigen isoform b precursor [Homo sapiens] Length = 376 Score = 770 bits (1989), Expect = 0.0 Identities = 376/388 (96%), Positives = 376/388 (96%), Gaps = 12/388 (3%) Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60 Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120 Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180 Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240 Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH Sbjct: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300 Query: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQ SPVFLMGANTQDTKNS Sbjct: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQ------------SPVFLMGANTQDTKNS 348 Query: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388 RHQFCLAQVSWIKNRVLKKWKTRLNQLW Sbjct: 349 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 376 >gi|110618234 CD1E antigen isoform d precursor [Homo sapiens] Length = 321 Score = 603 bits (1556), Expect = e-173 Identities = 310/388 (79%), Positives = 315/388 (81%), Gaps = 67/388 (17%) Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60 Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120 Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180 Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240 Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300 WVMWMR GG+ + + Sbjct: 241 WVMWMR----------------------------------------------GGYSIFL- 253 Query: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360 LI + + V TLVILVVVDSRLKKQ SPVFLMGANTQDTKNS Sbjct: 254 ------ILICLTVIV--TLVILVVVDSRLKKQ------------SPVFLMGANTQDTKNS 293 Query: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388 RHQFCLAQVSWIKNRVLKKWKTRLNQLW Sbjct: 294 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 321 >gi|110618232 CD1E antigen isoform c precursor [Homo sapiens] Length = 290 Score = 562 bits (1449), Expect = e-160 Identities = 267/269 (99%), Positives = 269/269 (100%) Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60 Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120 Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180 Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240 Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYL 269 WVMWMRGEQEQRGTQRGDVLPNADETW++ Sbjct: 241 WVMWMRGEQEQRGTQRGDVLPNADETWWI 269 >gi|4502649 CD1D antigen precursor [Homo sapiens] Length = 335 Score = 363 bits (932), Expect = e-100 Identities = 185/342 (54%), Positives = 234/342 (68%), Gaps = 15/342 (4%) Query: 3 LLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGDL 62 LLFLL L + PQ L R LQ SSFAN SW ++G WLG+L Sbjct: 4 LLFLLLWALLQAWGSAEVPQRL----------FPLRCLQISSFANSSWTRTDGLAWLGEL 53 Query: 63 QTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFE 122 QTH W T+R LKPWS G FS Q+ + LQ +F++Y SF + V+ A +L YP E Sbjct: 54 QTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLE 113 Query: 123 IQILAGCRM---NAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIK 179 +Q+ AGC + NA F ++A+QG D LSFQG SWEP+ A + +VLN+ + Sbjct: 114 LQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTR 173 Query: 180 EILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKP 239 E +Q LL TCP+F++GL+E+G+SELK++VKP+AWLS GPSPGPGRL LVCHVSGFYPKP Sbjct: 174 ETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKP 233 Query: 240 VWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLII 299 VWV WMRGEQEQ+GTQ GD+LPNADETWYLRATLDV AGEAAGLSCRVKHSSL G D+++ Sbjct: 234 VWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVL 293 Query: 300 HWGGYSIFLILICLTVIVTLVILVVV--DSRLKKQSSNKNIL 339 +WGG + LI L V+ L+ L++V SR K+Q+S + +L Sbjct: 294 YWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL 335 >gi|4502645 CD1B antigen precursor [Homo sapiens] Length = 333 Score = 358 bits (919), Expect = 5e-99 Identities = 183/341 (53%), Positives = 236/341 (69%), Gaps = 12/341 (3%) Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60 MLLL + PG N S H A + SF ++QTSSF N +WA ++GSGWL Sbjct: 1 MLLLPFQLLAVLFPGGN--------SEH-AFQGPTSFHVIQTSSFTNSTWAQTQGSGWLD 51 Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120 DLQ HGWD+ GT FLKPWS GNFS +E+ L+ +F++Y F + VQ AG FQ++YP Sbjct: 52 DLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYP 111 Query: 121 FEIQILAGCRMN---APQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLD 177 FEIQ +AGC ++ A FL A G DFLS + S PSP G RAQ C ++ +Y Sbjct: 112 FEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQG 171 Query: 178 IKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYP 237 I E ++ LL TCPR+L G++ AG+++L+R+VKPEAWLS GPSPGPGRLQLVCHVSGFYP Sbjct: 172 IMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYP 231 Query: 238 KPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDL 297 KPVWVMWMRGEQEQ+GTQ GD+LPNA+ TWYLRATLDVA GEAAGLSCRVKHSSL G D+ Sbjct: 232 KPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDI 291 Query: 298 IIHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNI 338 I++W + ++ ++ +L++L+ + ++ S +NI Sbjct: 292 ILYWRNPTSIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNI 332 >gi|110618224 CD1A antigen precursor [Homo sapiens] Length = 327 Score = 357 bits (915), Expect = 1e-98 Identities = 181/325 (55%), Positives = 230/325 (70%), Gaps = 14/325 (4%) Query: 3 LLFLLFEGLCC-PGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61 +LFLL L PG+ A +E LSF + +SF NHSW + SGWL D Sbjct: 1 MLFLLLPLLAVLPGDGNAD---------GLKEPLSFHVTWIASFYNHSWKQNLVSGWLSD 51 Query: 62 LQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPF 121 LQTH WD+ TI FL PWS GNFS +E K L++LF++ + ++ A + Q EYPF Sbjct: 52 LQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPF 111 Query: 122 EIQILAGCRMNAPQI---FLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDI 178 EIQ+ GC +++ ++ FL +AYQGSDF+SFQ SW P P AG A++ CKVLN+ Sbjct: 112 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHE 171 Query: 179 KEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPK 238 +I +LL TCPRF+ GL++AG++ L+R+VKPEAWLS GPSPGPG LQLVCHVSGFYPK Sbjct: 172 NDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPK 231 Query: 239 PVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLI 298 PVWVMWMRGEQEQ+GTQRGD+LP+AD TWYLRATL+VAAGEAA LSCRVKHSSL G D++ Sbjct: 232 PVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIV 291 Query: 299 IHWGGYSIFLILICLTVIVTLVILV 323 ++W +S +I L VIV L++L+ Sbjct: 292 LYWEHHSSVGFII-LAVIVPLLLLI 315 >gi|110618236 CD1E antigen isoform e precursor [Homo sapiens] Length = 187 Score = 345 bits (886), Expect = 3e-95 Identities = 168/180 (93%), Positives = 168/180 (93%), Gaps = 12/180 (6%) Query: 209 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 268 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79 Query: 269 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 328 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR Sbjct: 80 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 139 Query: 329 LKKQSSNKNILSPHTPSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 388 LKKQ SPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW Sbjct: 140 LKKQ------------SPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 187 Score = 44.7 bits (104), Expect = 1e-04 Identities = 21/24 (87%), Positives = 22/24 (91%), Gaps = 1/24 (4%) Query: 1 MLLLFLLFEGLCCPGENTAA-PQA 23 MLLLFLLFEGLCCPGENTA P+A Sbjct: 1 MLLLFLLFEGLCCPGENTAVKPEA 24 >gi|110618227 CD1C antigen precursor [Homo sapiens] Length = 333 Score = 345 bits (886), Expect = 3e-95 Identities = 175/343 (51%), Positives = 230/343 (67%), Gaps = 14/343 (4%) Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60 ML L L L PG + A A++E +SF ++Q SF N SWA +GSGWL Sbjct: 1 MLFLQFLLLALLLPGGDNAD---------ASQEHVSFHVIQIFSFVNQSWARGQGSGWLD 51 Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120 +LQTHGWD+ GTI FL WS GNFS +EL +L+ LF+ Y + +Q A Q +YP Sbjct: 52 ELQTHGWDSESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYP 111 Query: 121 FEIQILAGCRMNA---PQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLN-RYL 176 FE+Q+ AGC +++ P+ F +A+ G D LSFQ +W PSPG G AQ++C +LN +Y Sbjct: 112 FEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYE 171 Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236 + E + +L+ TCPRFL GL++AG+ + R+V+PEAWLS PS G G+L LVCH SGFY Sbjct: 172 GVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFY 231 Query: 237 PKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHD 296 PKPVWV WMR EQEQ GT+ GD+LPNAD TWYL+ L+VA+ E AGLSCRV+HSSLGG D Sbjct: 232 PKPVWVTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQD 291 Query: 297 LIIHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339 +I++W G+ + I L VIV LVIL+V+ KK S ++IL Sbjct: 292 IILYW-GHHFSMNWIALVVIVPLVILIVLVLWFKKHCSYQDIL 333 >gi|110618238 CD1E antigen isoform f precursor [Homo sapiens] Length = 101 Score = 137 bits (346), Expect = 1e-32 Identities = 59/61 (96%), Positives = 61/61 (100%) Query: 209 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 268 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETW+ Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWW 79 Query: 269 L 269 + Sbjct: 80 I 80 Score = 44.7 bits (104), Expect = 1e-04 Identities = 21/24 (87%), Positives = 22/24 (91%), Gaps = 1/24 (4%) Query: 1 MLLLFLLFEGLCCPGENTAA-PQA 23 MLLLFLLFEGLCCPGENTA P+A Sbjct: 1 MLLLFLLFEGLCCPGENTAVKPEA 24 >gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo sapiens] Length = 365 Score = 73.6 bits (179), Expect = 3e-13 Identities = 83/304 (27%), Positives = 126/304 (41%), Gaps = 47/304 (15%) Query: 2 LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61 LLLFLL PG A YHL A +S T +F W SGWLG Sbjct: 13 LLLFLL------PGSLGAESHLSLLYHLTA---VSSPAPGTPAF----WV----SGWLGP 55 Query: 62 LQTHGWDTVLGTIRFLKPWSHGN----FSKQELKNLQSLFQLYFHSFIQIVQASAGQFQL 117 Q ++++ G W N + ++E +L+ +L+ +F +A G+ Sbjct: 56 QQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGGKG-- 109 Query: 118 EYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSFQ------GISWEPSPGAGIRAQNI 168 P+ +Q L GC + N A G +F++F G W + R Q Sbjct: 110 --PYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQ 167 Query: 169 CKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQL 228 K N+ L + L +CP L +E G L+ K P L PS PG L Sbjct: 168 DKAANKEL-------TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVL 219 Query: 229 VCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVK 288 C FYP + + ++R GT +GD PN+D +++ ++L V +G+ C V+ Sbjct: 220 TCSAFSFYPPELQLRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQ 278 Query: 289 HSSL 292 H+ L Sbjct: 279 HAGL 282 >gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo sapiens] Length = 365 Score = 73.6 bits (179), Expect = 3e-13 Identities = 83/304 (27%), Positives = 126/304 (41%), Gaps = 47/304 (15%) Query: 2 LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61 LLLFLL PG A YHL A +S T +F W SGWLG Sbjct: 13 LLLFLL------PGSLGAESHLSLLYHLTA---VSSPAPGTPAF----WV----SGWLGP 55 Query: 62 LQTHGWDTVLGTIRFLKPWSHGN----FSKQELKNLQSLFQLYFHSFIQIVQASAGQFQL 117 Q ++++ G W N + ++E +L+ +L+ +F +A G+ Sbjct: 56 QQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGGKG-- 109 Query: 118 EYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSFQ------GISWEPSPGAGIRAQNI 168 P+ +Q L GC + N A G +F++F G W + R Q Sbjct: 110 --PYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQ 167 Query: 169 CKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQL 228 K N+ L + L +CP L +E G L+ K P L PS PG L Sbjct: 168 DKAANKEL-------TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVL 219 Query: 229 VCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVK 288 C FYP + + ++R GT +GD PN+D +++ ++L V +G+ C V+ Sbjct: 220 TCSAFSFYPPELQLRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQ 278 Query: 289 HSSL 292 H+ L Sbjct: 279 HAGL 282 >gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sapiens] Length = 260 Score = 66.2 bits (160), Expect = 5e-11 Identities = 58/246 (23%), Positives = 109/246 (44%), Gaps = 17/246 (6%) Query: 105 IQIVQASAGQFQLEYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSF--QGISWEPSP 159 + ++Q + Q +L +Q++ GC M N+ + + Y G D L F + W Sbjct: 12 LMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWR--- 68 Query: 160 GAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGP 219 A RA R+ ++ L CP L L+E G L ++V P ++ Sbjct: 69 AAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHV 128 Query: 220 SPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAA 277 + L+ C +YP+ + + W++ +Q + + + DVLPN D T+ TL V Sbjct: 129 TSSVTTLR--CRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPP 186 Query: 278 GEAAGLSCRVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQS 333 GE +C+V+H L LI+ W G + ++ + V V ++ + ++ L+K+ Sbjct: 187 GEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 245 Query: 334 SNKNIL 339 ++ + Sbjct: 246 GSRGAM 251 >gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sapiens] Length = 325 Score = 65.1 bits (157), Expect = 1e-10 Identities = 62/273 (22%), Positives = 112/273 (41%), Gaps = 18/273 (6%) Query: 79 PWSHGNFSKQELKNLQSLFQLYFHSF-IQIVQASAGQFQLEYPFEIQILAGCRM---NAP 134 PW S Q L + + H F + + +Q++ GC M N+ Sbjct: 50 PWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNST 109 Query: 135 QIFLNMAYQGSDFLSF--QGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPR 192 + + Y G D L F + W A RA R+ ++ L CP Sbjct: 110 EGYWKYGYDGQDHLEFCPDTLDWR---AAEPRAWPTKLEWERHKIRARQNRAYLERDCPA 166 Query: 193 FLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--E 250 L L+E G L ++V P ++ + L+ C +YP+ + + W++ +Q + Sbjct: 167 QLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRALNYYPQNITMKWLKDKQPMD 224 Query: 251 QRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHW----GGYSI 306 + + DVLPN D T+ TL V GE +C+V+H L LI+ W G + Sbjct: 225 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLV 283 Query: 307 FLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339 ++ + V V ++ + ++ L+K+ ++ + Sbjct: 284 IGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316 >gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sapiens] Length = 348 Score = 65.1 bits (157), Expect = 1e-10 Identities = 62/273 (22%), Positives = 112/273 (41%), Gaps = 18/273 (6%) Query: 79 PWSHGNFSKQELKNLQSLFQLYFHSF-IQIVQASAGQFQLEYPFEIQILAGCRM---NAP 134 PW S Q L + + H F + + +Q++ GC M N+ Sbjct: 73 PWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNST 132 Query: 135 QIFLNMAYQGSDFLSF--QGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPR 192 + + Y G D L F + W A RA R+ ++ L CP Sbjct: 133 EGYWKYGYDGQDHLEFCPDTLDWR---AAEPRAWPTKLEWERHKIRARQNRAYLERDCPA 189 Query: 193 FLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--E 250 L L+E G L ++V P ++ + L+ C +YP+ + + W++ +Q + Sbjct: 190 QLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRALNYYPQNITMKWLKDKQPMD 247 Query: 251 QRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHW----GGYSI 306 + + DVLPN D T+ TL V GE +C+V+H L LI+ W G + Sbjct: 248 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLV 306 Query: 307 FLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339 ++ + V V ++ + ++ L+K+ ++ + Sbjct: 307 IGVISGIAVFVVILFIGILFIILRKRQGSRGAM 339 >gi|4504417 major histocompatibility complex, class I-related [Homo sapiens] Length = 341 Score = 64.3 bits (155), Expect = 2e-10 Identities = 59/257 (22%), Positives = 110/257 (42%), Gaps = 21/257 (8%) Query: 79 PWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFEIQILAGCRM---NAPQ 135 PW N + + L + + F ++ + Q + GC + + Sbjct: 70 PWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTT 129 Query: 136 IFLNMAYQGSDFLSFQG--ISWEPSPGAGIRAQNICKVLNRYLDIK--EIL--QSLLGHT 189 FL AY G DFL F +SW + N+ + + + E+L ++ L Sbjct: 130 GFLQYAYDGQDFLIFNKDTLSW-------LAVDNVAHTIKQAWEANQHELLYQKNWLEEE 182 Query: 190 CPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMR-GE 248 C +L +E G+ L+R P ++ PG L C GFYP +++ WM+ GE Sbjct: 183 CIAWLKRFLEYGKDTLQRTEPPLVRVN-RKETFPGVTALFCKAHGFYPPEIYMTWMKNGE 241 Query: 249 QEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFL 308 + + GD+LP+ D T+ A++++ + SC V+H G +++ S + Sbjct: 242 EIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHC---GVHMVLQVPQESETI 298 Query: 309 ILICLTVIVTLVILVVV 325 L+ V ++V+++V+ Sbjct: 299 PLVMKAVSGSIVLVIVL 315 >gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapiens] Length = 366 Score = 62.8 bits (151), Expect = 5e-10 Identities = 61/224 (27%), Positives = 99/224 (44%), Gaps = 16/224 (7%) Query: 123 IQILAGCRMNAPQIFLNM----AYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176 +Q++ GC + FL AY G D+++ SW A A I K Sbjct: 132 LQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWT----AADTAAQITKRKREAA 187 Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236 E ++ L C L +E G+ L R P+A ++ P + L C GFY Sbjct: 188 GAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPI-SEREVTLRCWALGFY 246 Query: 237 PKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGH 295 P+ + + W R GE + + + + P+ D T+ A L V +GE +CRV+H L Sbjct: 247 PEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGL-QE 305 Query: 296 DLIIHW-GGYSIFLILICLTVIVTLVILVVVDSRL--KKQSSNK 336 L + W + FLI+ + +V LV+ +V + + KK+S + Sbjct: 306 PLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKRSGRE 349 >gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sapiens] Length = 246 Score = 62.4 bits (150), Expect = 7e-10 Identities = 57/246 (23%), Positives = 104/246 (42%), Gaps = 31/246 (12%) Query: 105 IQIVQASAGQFQLEYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSF--QGISWEPSP 159 + ++Q + Q +L +Q++ GC M N+ + + Y G D L F + W Sbjct: 12 LMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWR--- 68 Query: 160 GAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGP 219 A RA R+ ++ L CP L L+E G L ++V Sbjct: 69 AAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT-------- 120 Query: 220 SPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAA 277 L C +YP+ + + W++ +Q + + + DVLPN D T+ TL V Sbjct: 121 --------LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPP 172 Query: 278 GEAAGLSCRVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQS 333 GE +C+V+H L LI+ W G + ++ + V V ++ + ++ L+K+ Sbjct: 173 GEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 231 Query: 334 SNKNIL 339 ++ + Sbjct: 232 GSRGAM 237 >gi|149158702 major histocompatibility complex, class I, F isoform 1 precursor [Homo sapiens] Length = 442 Score = 61.2 bits (147), Expect = 2e-09 Identities = 60/236 (25%), Positives = 94/236 (39%), Gaps = 27/236 (11%) Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176 +Q + GC M L AY G D++S SW A + ++ R+ Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTA-------ADTVAQITQRFY 168 Query: 177 DIKEILQSL---LGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVS 233 + +E + L C L +E G+ L+R P+A ++ P L C Sbjct: 169 EAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWAL 227 Query: 234 GFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSL 292 GFYP + + W R GE++ + T+ + P D T+ A + V GE +C V+H L Sbjct: 228 GFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGL 287 Query: 293 GGHDLIIHWGG--------YSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILS 340 LI+ W I L+ L +VT ++ V R K N+ S Sbjct: 288 -PQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYS 342 >gi|149158698 major histocompatibility complex, class I, F isoform 2 precursor [Homo sapiens] Length = 346 Score = 61.2 bits (147), Expect = 2e-09 Identities = 60/236 (25%), Positives = 94/236 (39%), Gaps = 27/236 (11%) Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176 +Q + GC M L AY G D++S SW A + ++ R+ Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTA-------ADTVAQITQRFY 168 Query: 177 DIKEILQSL---LGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVS 233 + +E + L C L +E G+ L+R P+A ++ P L C Sbjct: 169 EAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWAL 227 Query: 234 GFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSL 292 GFYP + + W R GE++ + T+ + P D T+ A + V GE +C V+H L Sbjct: 228 GFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGL 287 Query: 293 GGHDLIIHWGG--------YSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILS 340 LI+ W I L+ L +VT ++ V R K N+ S Sbjct: 288 -PQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYS 342 >gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sapiens] Length = 334 Score = 61.2 bits (147), Expect = 2e-09 Identities = 61/273 (22%), Positives = 107/273 (39%), Gaps = 32/273 (11%) Query: 79 PWSHGNFSKQELKNLQSLFQLYFHSF-IQIVQASAGQFQLEYPFEIQILAGCRM---NAP 134 PW S Q L + + H F + + +Q++ GC M N+ Sbjct: 73 PWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNST 132 Query: 135 QIFLNMAYQGSDFLSF--QGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPR 192 + + Y G D L F + W A RA R+ ++ L CP Sbjct: 133 EGYWKYGYDGQDHLEFCPDTLDWR---AAEPRAWPTKLEWERHKIRARQNRAYLERDCPA 189 Query: 193 FLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--E 250 L L+E G L ++V L C +YP+ + + W++ +Q + Sbjct: 190 QLQQLLELGRGVLDQQVTT----------------LRCRALNYYPQNITMKWLKDKQPMD 233 Query: 251 QRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHW----GGYSI 306 + + DVLPN D T+ TL V GE +C+V+H L LI+ W G + Sbjct: 234 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLV 292 Query: 307 FLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339 ++ + V V ++ + ++ L+K+ ++ + Sbjct: 293 IGVISGIAVFVVILFIGILFIILRKRQGSRGAM 325 >gi|4504415 major histocompatibility complex, class I, G precursor [Homo sapiens] Length = 338 Score = 60.8 bits (146), Expect = 2e-09 Identities = 55/210 (26%), Positives = 93/210 (44%), Gaps = 14/210 (6%) Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176 +Q + GC + + L AY G D+L+ SW + A ++ C+ N Sbjct: 119 LQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN--- 175 Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236 + E ++ L TC +L +E G+ L+R P+ ++ P L C GFY Sbjct: 176 -VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPV-FDYEATLRCWALGFY 233 Query: 237 PKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGH 295 P + + W R GE + + + + P D T+ A + V +GE +C V+H L Sbjct: 234 PAEIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL-PE 292 Query: 296 DLIIHWGGYSIFLILICLTVIVTLVILVVV 325 L++ W S+ I I + ++ LV+L V Sbjct: 293 PLMLRWKQSSLPTIPI-MGIVAGLVVLAAV 321 >gi|24797067 major histocompatibility complex, class I, A precursor [Homo sapiens] Length = 365 Score = 60.8 bits (146), Expect = 2e-09 Identities = 63/229 (27%), Positives = 96/229 (41%), Gaps = 22/229 (9%) Query: 123 IQILAGCRMNAPQIFLNM----AYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176 IQI+ GC + + FL AY G D+++ SW A A I K Sbjct: 119 IQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWT----AADMAAQITKRKWEAA 174 Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236 E L++ L TC +L +E G+ L+R P+ ++ P L C GFY Sbjct: 175 HEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPI-SDHEATLRCWALGFY 233 Query: 237 PKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGH 295 P + + W R GE + + T+ + P D T+ A + V +GE +C V+H L Sbjct: 234 PAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL-PK 292 Query: 296 DLIIHWGGYS--------IFLILICLTVIVTLVILVVVDSRLKKQSSNK 336 L + W S I L+ L ++T ++ V R +K S K Sbjct: 293 PLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWR-RKSSDRK 340 >gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] Length = 298 Score = 59.7 bits (143), Expect = 4e-09 Identities = 76/310 (24%), Positives = 121/310 (39%), Gaps = 30/310 (9%) Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60 +LL LL G P EN +L + LS + +F + G L Sbjct: 7 VLLSLLLLLGPAVPQENQDGRYSLTYIYTG----LSKHVEDVPAF--------QALGSLN 54 Query: 61 DLQTHGWDTV------LGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQ 114 DLQ +++ +G R ++ Q K + +F ++ S G Sbjct: 55 DLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGS 114 Query: 115 FQLEYPFEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGI--SWEP-SPGAGIRAQNICKV 171 L+ F +I A F Y G D++ F +W P P A I Q + Sbjct: 115 HVLQGRFGCEIENNRSSGA---FWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQK-WEA 170 Query: 172 LNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCH 231 Y+ + ++ L CP L ++ ++ L R+ P ++ +PG + +L C Sbjct: 171 EPVYV---QRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKK-KLKCL 226 Query: 232 VSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSS 291 FYP + V W R + Q RGDVL N + T+ + V + A SC V+HSS Sbjct: 227 AYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSS 286 Query: 292 LGGHDLIIHW 301 L L++ W Sbjct: 287 L-AQPLVVPW 295 >gi|52630342 major histocompatibility complex, class I, C precursor [Homo sapiens] Length = 366 Score = 57.8 bits (138), Expect = 2e-08 Identities = 59/229 (25%), Positives = 98/229 (42%), Gaps = 26/229 (11%) Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176 +Q ++GC + L AY G D+++ SW A ++ R L Sbjct: 119 LQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTA-------ADTAAQITQRKL 171 Query: 177 DIK---EILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVS 233 + E L++ L TC +L +E G+ L+R P+ ++ P L C Sbjct: 172 EAARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPL-SDHEATLRCWAL 230 Query: 234 GFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSL 292 GFYP + + W R GE + + T+ + P D T+ A + V +G+ +C ++H L Sbjct: 231 GFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGL 290 Query: 293 GGHDLIIHWGGYS-----IFLILICLTVIVTLVIL--VVVDSRLKKQSS 334 L + W S I I+ L V+V L +L VV +++SS Sbjct: 291 -QEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSS 338 >gi|17986001 major histocompatibility complex, class I, B precursor [Homo sapiens] Length = 362 Score = 54.3 bits (129), Expect = 2e-07 Identities = 63/261 (24%), Positives = 106/261 (40%), Gaps = 34/261 (13%) Query: 87 KQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFEIQILAGCRMNAPQIFLN----MAY 142 ++ L+NL+ + Q+ AG L Q + GC + L AY Sbjct: 99 RESLRNLRGYYN----------QSEAGSHTL------QSMYGCDVGPDGRLLRGHDQYAY 142 Query: 143 QGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEA 200 G D+++ SW + A Q + E ++ L C +L +E Sbjct: 143 DGKDYIALNEDLRSWTAADTAAQITQRKWEAARE----AEQRRAYLEGECVEWLRRYLEN 198 Query: 201 GESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDV 259 G+ +L+R P+ ++ P L C GFYP + + W R GE + + T+ + Sbjct: 199 GKDKLERADPPKTHVTHHPI-SDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVET 257 Query: 260 LPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYS-----IFLILICLT 314 P D T+ A + V +GE +C V+H L L + W S I I+ L Sbjct: 258 RPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGL-PKPLTLRWEPSSQSTVPIVGIVAGLA 316 Query: 315 VIVTLVILVVVDSRLKKQSSN 335 V+ +VI VV + + ++ S+ Sbjct: 317 VLAVVVIGAVVAAVMCRRKSS 337 >gi|24797076 major histocompatibility complex, class II, DP beta 1 precursor [Homo sapiens] Length = 258 Score = 52.4 bits (124), Expect = 7e-07 Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 9/110 (8%) Query: 201 GESELKRKVKPEAWLSCGPSPGPGRLQ----LVCHVSGFYPKPVWVMW-MRGEQEQRGTQ 255 G L+R+V+P +S PS G LQ LVCHV+ FYP + V W + G++E G Sbjct: 114 GPMTLQRRVQPRVNVS--PSK-KGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVV 170 Query: 256 RGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYS 305 +++ N D T+ + L++ + +C+V+H+SL + + W S Sbjct: 171 STNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDS-PVTVEWKAQS 219 >gi|62912479 major histocompatibility complex, class I, E precursor [Homo sapiens] Length = 358 Score = 50.1 bits (118), Expect = 3e-06 Identities = 49/191 (25%), Positives = 77/191 (40%), Gaps = 18/191 (9%) Query: 109 QASAGQFQLEYPFEIQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAG 162 Q+ AG L++ + GC + FL AY G D+L+ SW A Sbjct: 108 QSEAGSHTLQW------MHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWT----AV 157 Query: 163 IRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPG 222 A I + + E ++ L TC +L +E G+ L P+ ++ P Sbjct: 158 DTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPI-S 216 Query: 223 PGRLQLVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAA 281 L C GFYP + + W + GE + T+ + P D T+ A + V +GE Sbjct: 217 DHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQ 276 Query: 282 GLSCRVKHSSL 292 +C V+H L Sbjct: 277 RYTCHVQHEGL 287 >gi|21040355 hemochromatosis protein isoform 10 precursor [Homo sapiens] Length = 168 Score = 48.9 bits (115), Expect = 8e-06 Identities = 30/118 (25%), Positives = 59/118 (50%), Gaps = 7/118 (5%) Query: 228 LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 285 L C +YP+ + + W++ +Q + + + DVLPN D T+ TL V GE +C Sbjct: 43 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102 Query: 286 RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339 +V+H L LI+ W G + ++ + V V ++ + ++ L+K+ ++ + Sbjct: 103 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 159 >gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sapiens] Length = 256 Score = 48.9 bits (115), Expect = 8e-06 Identities = 30/118 (25%), Positives = 59/118 (50%), Gaps = 7/118 (5%) Query: 228 LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 285 L C +YP+ + + W++ +Q + + + DVLPN D T+ TL V GE +C Sbjct: 131 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 190 Query: 286 RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339 +V+H L LI+ W G + ++ + V V ++ + ++ L+K+ ++ + Sbjct: 191 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 247 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.137 0.439 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,026,709 Number of Sequences: 37866 Number of extensions: 744192 Number of successful extensions: 2111 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 63 Number of HSP's successfully gapped in prelim test: 36 Number of HSP's that attempted gapping in prelim test: 1965 Number of HSP's gapped (non-prelim): 115 length of query: 388 length of database: 18,247,518 effective HSP length: 104 effective length of query: 284 effective length of database: 14,309,454 effective search space: 4063884936 effective search space used: 4063884936 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.