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Search of human proteins with 110618240
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]
(388 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110618240 CD1E antigen isoform a precursor [Homo sapiens] 804 0.0
gi|110618230 CD1E antigen isoform b precursor [Homo sapiens] 770 0.0
gi|110618234 CD1E antigen isoform d precursor [Homo sapiens] 603 e-173
gi|110618232 CD1E antigen isoform c precursor [Homo sapiens] 562 e-160
gi|4502649 CD1D antigen precursor [Homo sapiens] 363 e-100
gi|4502645 CD1B antigen precursor [Homo sapiens] 358 5e-99
gi|110618224 CD1A antigen precursor [Homo sapiens] 357 1e-98
gi|110618236 CD1E antigen isoform e precursor [Homo sapiens] 345 3e-95
gi|110618227 CD1C antigen precursor [Homo sapiens] 345 3e-95
gi|110618238 CD1E antigen isoform f precursor [Homo sapiens] 137 1e-32
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 74 3e-13
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 74 3e-13
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 66 5e-11
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 65 1e-10
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 65 1e-10
gi|4504417 major histocompatibility complex, class I-related [Ho... 64 2e-10
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 63 5e-10
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 62 7e-10
gi|149158702 major histocompatibility complex, class I, F isofor... 61 2e-09
gi|149158698 major histocompatibility complex, class I, F isofor... 61 2e-09
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 61 2e-09
gi|4504415 major histocompatibility complex, class I, G precurso... 61 2e-09
gi|24797067 major histocompatibility complex, class I, A precurs... 61 2e-09
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 60 4e-09
gi|52630342 major histocompatibility complex, class I, C precurs... 58 2e-08
gi|17986001 major histocompatibility complex, class I, B precurs... 54 2e-07
gi|24797076 major histocompatibility complex, class II, DP beta ... 52 7e-07
gi|62912479 major histocompatibility complex, class I, E precurs... 50 3e-06
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 49 8e-06
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 49 8e-06
>gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]
Length = 388
Score = 804 bits (2076), Expect = 0.0
Identities = 388/388 (100%), Positives = 388/388 (100%)
Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE
Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV
Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300
WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH
Sbjct: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300
Query: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360
WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS
Sbjct: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360
Query: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388
RHQFCLAQVSWIKNRVLKKWKTRLNQLW
Sbjct: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388
>gi|110618230 CD1E antigen isoform b precursor [Homo sapiens]
Length = 376
Score = 770 bits (1989), Expect = 0.0
Identities = 376/388 (96%), Positives = 376/388 (96%), Gaps = 12/388 (3%)
Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE
Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV
Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300
WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH
Sbjct: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300
Query: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360
WGGYSIFLILICLTVIVTLVILVVVDSRLKKQ SPVFLMGANTQDTKNS
Sbjct: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQ------------SPVFLMGANTQDTKNS 348
Query: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388
RHQFCLAQVSWIKNRVLKKWKTRLNQLW
Sbjct: 349 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 376
>gi|110618234 CD1E antigen isoform d precursor [Homo sapiens]
Length = 321
Score = 603 bits (1556), Expect = e-173
Identities = 310/388 (79%), Positives = 315/388 (81%), Gaps = 67/388 (17%)
Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE
Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV
Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300
WVMWMR GG+ + +
Sbjct: 241 WVMWMR----------------------------------------------GGYSIFL- 253
Query: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360
LI + + V TLVILVVVDSRLKKQ SPVFLMGANTQDTKNS
Sbjct: 254 ------ILICLTVIV--TLVILVVVDSRLKKQ------------SPVFLMGANTQDTKNS 293
Query: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388
RHQFCLAQVSWIKNRVLKKWKTRLNQLW
Sbjct: 294 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 321
>gi|110618232 CD1E antigen isoform c precursor [Homo sapiens]
Length = 290
Score = 562 bits (1449), Expect = e-160
Identities = 267/269 (99%), Positives = 269/269 (100%)
Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE
Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV
Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYL 269
WVMWMRGEQEQRGTQRGDVLPNADETW++
Sbjct: 241 WVMWMRGEQEQRGTQRGDVLPNADETWWI 269
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 363 bits (932), Expect = e-100
Identities = 185/342 (54%), Positives = 234/342 (68%), Gaps = 15/342 (4%)
Query: 3 LLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGDL 62
LLFLL L + PQ L R LQ SSFAN SW ++G WLG+L
Sbjct: 4 LLFLLLWALLQAWGSAEVPQRL----------FPLRCLQISSFANSSWTRTDGLAWLGEL 53
Query: 63 QTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFE 122
QTH W T+R LKPWS G FS Q+ + LQ +F++Y SF + V+ A +L YP E
Sbjct: 54 QTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLE 113
Query: 123 IQILAGCRM---NAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIK 179
+Q+ AGC + NA F ++A+QG D LSFQG SWEP+ A + +VLN+ +
Sbjct: 114 LQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTR 173
Query: 180 EILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKP 239
E +Q LL TCP+F++GL+E+G+SELK++VKP+AWLS GPSPGPGRL LVCHVSGFYPKP
Sbjct: 174 ETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKP 233
Query: 240 VWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLII 299
VWV WMRGEQEQ+GTQ GD+LPNADETWYLRATLDV AGEAAGLSCRVKHSSL G D+++
Sbjct: 234 VWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVL 293
Query: 300 HWGGYSIFLILICLTVIVTLVILVVV--DSRLKKQSSNKNIL 339
+WGG + LI L V+ L+ L++V SR K+Q+S + +L
Sbjct: 294 YWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL 335
>gi|4502645 CD1B antigen precursor [Homo sapiens]
Length = 333
Score = 358 bits (919), Expect = 5e-99
Identities = 183/341 (53%), Positives = 236/341 (69%), Gaps = 12/341 (3%)
Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
MLLL + PG N S H A + SF ++QTSSF N +WA ++GSGWL
Sbjct: 1 MLLLPFQLLAVLFPGGN--------SEH-AFQGPTSFHVIQTSSFTNSTWAQTQGSGWLD 51
Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
DLQ HGWD+ GT FLKPWS GNFS +E+ L+ +F++Y F + VQ AG FQ++YP
Sbjct: 52 DLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYP 111
Query: 121 FEIQILAGCRMN---APQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLD 177
FEIQ +AGC ++ A FL A G DFLS + S PSP G RAQ C ++ +Y
Sbjct: 112 FEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQG 171
Query: 178 IKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYP 237
I E ++ LL TCPR+L G++ AG+++L+R+VKPEAWLS GPSPGPGRLQLVCHVSGFYP
Sbjct: 172 IMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYP 231
Query: 238 KPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDL 297
KPVWVMWMRGEQEQ+GTQ GD+LPNA+ TWYLRATLDVA GEAAGLSCRVKHSSL G D+
Sbjct: 232 KPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDI 291
Query: 298 IIHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNI 338
I++W + ++ ++ +L++L+ + ++ S +NI
Sbjct: 292 ILYWRNPTSIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNI 332
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 357 bits (915), Expect = 1e-98
Identities = 181/325 (55%), Positives = 230/325 (70%), Gaps = 14/325 (4%)
Query: 3 LLFLLFEGLCC-PGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
+LFLL L PG+ A +E LSF + +SF NHSW + SGWL D
Sbjct: 1 MLFLLLPLLAVLPGDGNAD---------GLKEPLSFHVTWIASFYNHSWKQNLVSGWLSD 51
Query: 62 LQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPF 121
LQTH WD+ TI FL PWS GNFS +E K L++LF++ + ++ A + Q EYPF
Sbjct: 52 LQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPF 111
Query: 122 EIQILAGCRMNAPQI---FLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDI 178
EIQ+ GC +++ ++ FL +AYQGSDF+SFQ SW P P AG A++ CKVLN+
Sbjct: 112 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHE 171
Query: 179 KEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPK 238
+I +LL TCPRF+ GL++AG++ L+R+VKPEAWLS GPSPGPG LQLVCHVSGFYPK
Sbjct: 172 NDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPK 231
Query: 239 PVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLI 298
PVWVMWMRGEQEQ+GTQRGD+LP+AD TWYLRATL+VAAGEAA LSCRVKHSSL G D++
Sbjct: 232 PVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIV 291
Query: 299 IHWGGYSIFLILICLTVIVTLVILV 323
++W +S +I L VIV L++L+
Sbjct: 292 LYWEHHSSVGFII-LAVIVPLLLLI 315
>gi|110618236 CD1E antigen isoform e precursor [Homo sapiens]
Length = 187
Score = 345 bits (886), Expect = 3e-95
Identities = 168/180 (93%), Positives = 168/180 (93%), Gaps = 12/180 (6%)
Query: 209 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 268
VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY
Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
Query: 269 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 328
LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR
Sbjct: 80 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 139
Query: 329 LKKQSSNKNILSPHTPSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 388
LKKQ SPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW
Sbjct: 140 LKKQ------------SPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 187
Score = 44.7 bits (104), Expect = 1e-04
Identities = 21/24 (87%), Positives = 22/24 (91%), Gaps = 1/24 (4%)
Query: 1 MLLLFLLFEGLCCPGENTAA-PQA 23
MLLLFLLFEGLCCPGENTA P+A
Sbjct: 1 MLLLFLLFEGLCCPGENTAVKPEA 24
>gi|110618227 CD1C antigen precursor [Homo sapiens]
Length = 333
Score = 345 bits (886), Expect = 3e-95
Identities = 175/343 (51%), Positives = 230/343 (67%), Gaps = 14/343 (4%)
Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
ML L L L PG + A A++E +SF ++Q SF N SWA +GSGWL
Sbjct: 1 MLFLQFLLLALLLPGGDNAD---------ASQEHVSFHVIQIFSFVNQSWARGQGSGWLD 51
Query: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
+LQTHGWD+ GTI FL WS GNFS +EL +L+ LF+ Y + +Q A Q +YP
Sbjct: 52 ELQTHGWDSESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYP 111
Query: 121 FEIQILAGCRMNA---PQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLN-RYL 176
FE+Q+ AGC +++ P+ F +A+ G D LSFQ +W PSPG G AQ++C +LN +Y
Sbjct: 112 FEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYE 171
Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
+ E + +L+ TCPRFL GL++AG+ + R+V+PEAWLS PS G G+L LVCH SGFY
Sbjct: 172 GVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFY 231
Query: 237 PKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHD 296
PKPVWV WMR EQEQ GT+ GD+LPNAD TWYL+ L+VA+ E AGLSCRV+HSSLGG D
Sbjct: 232 PKPVWVTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQD 291
Query: 297 LIIHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
+I++W G+ + I L VIV LVIL+V+ KK S ++IL
Sbjct: 292 IILYW-GHHFSMNWIALVVIVPLVILIVLVLWFKKHCSYQDIL 333
>gi|110618238 CD1E antigen isoform f precursor [Homo sapiens]
Length = 101
Score = 137 bits (346), Expect = 1e-32
Identities = 59/61 (96%), Positives = 61/61 (100%)
Query: 209 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 268
VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETW+
Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWW 79
Query: 269 L 269
+
Sbjct: 80 I 80
Score = 44.7 bits (104), Expect = 1e-04
Identities = 21/24 (87%), Positives = 22/24 (91%), Gaps = 1/24 (4%)
Query: 1 MLLLFLLFEGLCCPGENTAA-PQA 23
MLLLFLLFEGLCCPGENTA P+A
Sbjct: 1 MLLLFLLFEGLCCPGENTAVKPEA 24
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 73.6 bits (179), Expect = 3e-13
Identities = 83/304 (27%), Positives = 126/304 (41%), Gaps = 47/304 (15%)
Query: 2 LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
LLLFLL PG A YHL A +S T +F W SGWLG
Sbjct: 13 LLLFLL------PGSLGAESHLSLLYHLTA---VSSPAPGTPAF----WV----SGWLGP 55
Query: 62 LQTHGWDTVLGTIRFLKPWSHGN----FSKQELKNLQSLFQLYFHSFIQIVQASAGQFQL 117
Q ++++ G W N + ++E +L+ +L+ +F +A G+
Sbjct: 56 QQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGGKG-- 109
Query: 118 EYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSFQ------GISWEPSPGAGIRAQNI 168
P+ +Q L GC + N A G +F++F G W + R Q
Sbjct: 110 --PYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQ 167
Query: 169 CKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQL 228
K N+ L + L +CP L +E G L+ K P L PS PG L
Sbjct: 168 DKAANKEL-------TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVL 219
Query: 229 VCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVK 288
C FYP + + ++R GT +GD PN+D +++ ++L V +G+ C V+
Sbjct: 220 TCSAFSFYPPELQLRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQ 278
Query: 289 HSSL 292
H+ L
Sbjct: 279 HAGL 282
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 73.6 bits (179), Expect = 3e-13
Identities = 83/304 (27%), Positives = 126/304 (41%), Gaps = 47/304 (15%)
Query: 2 LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
LLLFLL PG A YHL A +S T +F W SGWLG
Sbjct: 13 LLLFLL------PGSLGAESHLSLLYHLTA---VSSPAPGTPAF----WV----SGWLGP 55
Query: 62 LQTHGWDTVLGTIRFLKPWSHGN----FSKQELKNLQSLFQLYFHSFIQIVQASAGQFQL 117
Q ++++ G W N + ++E +L+ +L+ +F +A G+
Sbjct: 56 QQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGGKG-- 109
Query: 118 EYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSFQ------GISWEPSPGAGIRAQNI 168
P+ +Q L GC + N A G +F++F G W + R Q
Sbjct: 110 --PYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQ 167
Query: 169 CKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQL 228
K N+ L + L +CP L +E G L+ K P L PS PG L
Sbjct: 168 DKAANKEL-------TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVL 219
Query: 229 VCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVK 288
C FYP + + ++R GT +GD PN+D +++ ++L V +G+ C V+
Sbjct: 220 TCSAFSFYPPELQLRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQ 278
Query: 289 HSSL 292
H+ L
Sbjct: 279 HAGL 282
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 66.2 bits (160), Expect = 5e-11
Identities = 58/246 (23%), Positives = 109/246 (44%), Gaps = 17/246 (6%)
Query: 105 IQIVQASAGQFQLEYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSF--QGISWEPSP 159
+ ++Q + Q +L +Q++ GC M N+ + + Y G D L F + W
Sbjct: 12 LMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWR--- 68
Query: 160 GAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGP 219
A RA R+ ++ L CP L L+E G L ++V P ++
Sbjct: 69 AAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHV 128
Query: 220 SPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAA 277
+ L+ C +YP+ + + W++ +Q + + + DVLPN D T+ TL V
Sbjct: 129 TSSVTTLR--CRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPP 186
Query: 278 GEAAGLSCRVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQS 333
GE +C+V+H L LI+ W G + ++ + V V ++ + ++ L+K+
Sbjct: 187 GEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 245
Query: 334 SNKNIL 339
++ +
Sbjct: 246 GSRGAM 251
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 65.1 bits (157), Expect = 1e-10
Identities = 62/273 (22%), Positives = 112/273 (41%), Gaps = 18/273 (6%)
Query: 79 PWSHGNFSKQELKNLQSLFQLYFHSF-IQIVQASAGQFQLEYPFEIQILAGCRM---NAP 134
PW S Q L + + H F + + +Q++ GC M N+
Sbjct: 50 PWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNST 109
Query: 135 QIFLNMAYQGSDFLSF--QGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPR 192
+ + Y G D L F + W A RA R+ ++ L CP
Sbjct: 110 EGYWKYGYDGQDHLEFCPDTLDWR---AAEPRAWPTKLEWERHKIRARQNRAYLERDCPA 166
Query: 193 FLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--E 250
L L+E G L ++V P ++ + L+ C +YP+ + + W++ +Q +
Sbjct: 167 QLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRALNYYPQNITMKWLKDKQPMD 224
Query: 251 QRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHW----GGYSI 306
+ + DVLPN D T+ TL V GE +C+V+H L LI+ W G +
Sbjct: 225 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLV 283
Query: 307 FLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
++ + V V ++ + ++ L+K+ ++ +
Sbjct: 284 IGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 65.1 bits (157), Expect = 1e-10
Identities = 62/273 (22%), Positives = 112/273 (41%), Gaps = 18/273 (6%)
Query: 79 PWSHGNFSKQELKNLQSLFQLYFHSF-IQIVQASAGQFQLEYPFEIQILAGCRM---NAP 134
PW S Q L + + H F + + +Q++ GC M N+
Sbjct: 73 PWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNST 132
Query: 135 QIFLNMAYQGSDFLSF--QGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPR 192
+ + Y G D L F + W A RA R+ ++ L CP
Sbjct: 133 EGYWKYGYDGQDHLEFCPDTLDWR---AAEPRAWPTKLEWERHKIRARQNRAYLERDCPA 189
Query: 193 FLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--E 250
L L+E G L ++V P ++ + L+ C +YP+ + + W++ +Q +
Sbjct: 190 QLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRALNYYPQNITMKWLKDKQPMD 247
Query: 251 QRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHW----GGYSI 306
+ + DVLPN D T+ TL V GE +C+V+H L LI+ W G +
Sbjct: 248 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLV 306
Query: 307 FLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
++ + V V ++ + ++ L+K+ ++ +
Sbjct: 307 IGVISGIAVFVVILFIGILFIILRKRQGSRGAM 339
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 64.3 bits (155), Expect = 2e-10
Identities = 59/257 (22%), Positives = 110/257 (42%), Gaps = 21/257 (8%)
Query: 79 PWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFEIQILAGCRM---NAPQ 135
PW N + + L + + F ++ + Q + GC + +
Sbjct: 70 PWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTT 129
Query: 136 IFLNMAYQGSDFLSFQG--ISWEPSPGAGIRAQNICKVLNRYLDIK--EIL--QSLLGHT 189
FL AY G DFL F +SW + N+ + + + E+L ++ L
Sbjct: 130 GFLQYAYDGQDFLIFNKDTLSW-------LAVDNVAHTIKQAWEANQHELLYQKNWLEEE 182
Query: 190 CPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMR-GE 248
C +L +E G+ L+R P ++ PG L C GFYP +++ WM+ GE
Sbjct: 183 CIAWLKRFLEYGKDTLQRTEPPLVRVN-RKETFPGVTALFCKAHGFYPPEIYMTWMKNGE 241
Query: 249 QEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFL 308
+ + GD+LP+ D T+ A++++ + SC V+H G +++ S +
Sbjct: 242 EIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHC---GVHMVLQVPQESETI 298
Query: 309 ILICLTVIVTLVILVVV 325
L+ V ++V+++V+
Sbjct: 299 PLVMKAVSGSIVLVIVL 315
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 62.8 bits (151), Expect = 5e-10
Identities = 61/224 (27%), Positives = 99/224 (44%), Gaps = 16/224 (7%)
Query: 123 IQILAGCRMNAPQIFLNM----AYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
+Q++ GC + FL AY G D+++ SW A A I K
Sbjct: 132 LQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWT----AADTAAQITKRKREAA 187
Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
E ++ L C L +E G+ L R P+A ++ P + L C GFY
Sbjct: 188 GAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPI-SEREVTLRCWALGFY 246
Query: 237 PKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGH 295
P+ + + W R GE + + + + P+ D T+ A L V +GE +CRV+H L
Sbjct: 247 PEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGL-QE 305
Query: 296 DLIIHW-GGYSIFLILICLTVIVTLVILVVVDSRL--KKQSSNK 336
L + W + FLI+ + +V LV+ +V + + KK+S +
Sbjct: 306 PLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKRSGRE 349
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 62.4 bits (150), Expect = 7e-10
Identities = 57/246 (23%), Positives = 104/246 (42%), Gaps = 31/246 (12%)
Query: 105 IQIVQASAGQFQLEYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSF--QGISWEPSP 159
+ ++Q + Q +L +Q++ GC M N+ + + Y G D L F + W
Sbjct: 12 LMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWR--- 68
Query: 160 GAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGP 219
A RA R+ ++ L CP L L+E G L ++V
Sbjct: 69 AAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT-------- 120
Query: 220 SPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAA 277
L C +YP+ + + W++ +Q + + + DVLPN D T+ TL V
Sbjct: 121 --------LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPP 172
Query: 278 GEAAGLSCRVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQS 333
GE +C+V+H L LI+ W G + ++ + V V ++ + ++ L+K+
Sbjct: 173 GEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 231
Query: 334 SNKNIL 339
++ +
Sbjct: 232 GSRGAM 237
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 61.2 bits (147), Expect = 2e-09
Identities = 60/236 (25%), Positives = 94/236 (39%), Gaps = 27/236 (11%)
Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
+Q + GC M L AY G D++S SW A + ++ R+
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTA-------ADTVAQITQRFY 168
Query: 177 DIKEILQSL---LGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVS 233
+ +E + L C L +E G+ L+R P+A ++ P L C
Sbjct: 169 EAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWAL 227
Query: 234 GFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSL 292
GFYP + + W R GE++ + T+ + P D T+ A + V GE +C V+H L
Sbjct: 228 GFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGL 287
Query: 293 GGHDLIIHWGG--------YSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILS 340
LI+ W I L+ L +VT ++ V R K N+ S
Sbjct: 288 -PQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYS 342
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 61.2 bits (147), Expect = 2e-09
Identities = 60/236 (25%), Positives = 94/236 (39%), Gaps = 27/236 (11%)
Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
+Q + GC M L AY G D++S SW A + ++ R+
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTA-------ADTVAQITQRFY 168
Query: 177 DIKEILQSL---LGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVS 233
+ +E + L C L +E G+ L+R P+A ++ P L C
Sbjct: 169 EAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWAL 227
Query: 234 GFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSL 292
GFYP + + W R GE++ + T+ + P D T+ A + V GE +C V+H L
Sbjct: 228 GFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGL 287
Query: 293 GGHDLIIHWGG--------YSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILS 340
LI+ W I L+ L +VT ++ V R K N+ S
Sbjct: 288 -PQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYS 342
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/273 (22%), Positives = 107/273 (39%), Gaps = 32/273 (11%)
Query: 79 PWSHGNFSKQELKNLQSLFQLYFHSF-IQIVQASAGQFQLEYPFEIQILAGCRM---NAP 134
PW S Q L + + H F + + +Q++ GC M N+
Sbjct: 73 PWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNST 132
Query: 135 QIFLNMAYQGSDFLSF--QGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPR 192
+ + Y G D L F + W A RA R+ ++ L CP
Sbjct: 133 EGYWKYGYDGQDHLEFCPDTLDWR---AAEPRAWPTKLEWERHKIRARQNRAYLERDCPA 189
Query: 193 FLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--E 250
L L+E G L ++V L C +YP+ + + W++ +Q +
Sbjct: 190 QLQQLLELGRGVLDQQVTT----------------LRCRALNYYPQNITMKWLKDKQPMD 233
Query: 251 QRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHW----GGYSI 306
+ + DVLPN D T+ TL V GE +C+V+H L LI+ W G +
Sbjct: 234 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLV 292
Query: 307 FLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
++ + V V ++ + ++ L+K+ ++ +
Sbjct: 293 IGVISGIAVFVVILFIGILFIILRKRQGSRGAM 325
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 60.8 bits (146), Expect = 2e-09
Identities = 55/210 (26%), Positives = 93/210 (44%), Gaps = 14/210 (6%)
Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
+Q + GC + + L AY G D+L+ SW + A ++ C+ N
Sbjct: 119 LQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN--- 175
Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
+ E ++ L TC +L +E G+ L+R P+ ++ P L C GFY
Sbjct: 176 -VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPV-FDYEATLRCWALGFY 233
Query: 237 PKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGH 295
P + + W R GE + + + + P D T+ A + V +GE +C V+H L
Sbjct: 234 PAEIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL-PE 292
Query: 296 DLIIHWGGYSIFLILICLTVIVTLVILVVV 325
L++ W S+ I I + ++ LV+L V
Sbjct: 293 PLMLRWKQSSLPTIPI-MGIVAGLVVLAAV 321
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 60.8 bits (146), Expect = 2e-09
Identities = 63/229 (27%), Positives = 96/229 (41%), Gaps = 22/229 (9%)
Query: 123 IQILAGCRMNAPQIFLNM----AYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
IQI+ GC + + FL AY G D+++ SW A A I K
Sbjct: 119 IQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWT----AADMAAQITKRKWEAA 174
Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
E L++ L TC +L +E G+ L+R P+ ++ P L C GFY
Sbjct: 175 HEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPI-SDHEATLRCWALGFY 233
Query: 237 PKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGH 295
P + + W R GE + + T+ + P D T+ A + V +GE +C V+H L
Sbjct: 234 PAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL-PK 292
Query: 296 DLIIHWGGYS--------IFLILICLTVIVTLVILVVVDSRLKKQSSNK 336
L + W S I L+ L ++T ++ V R +K S K
Sbjct: 293 PLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWR-RKSSDRK 340
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 59.7 bits (143), Expect = 4e-09
Identities = 76/310 (24%), Positives = 121/310 (39%), Gaps = 30/310 (9%)
Query: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
+LL LL G P EN +L + LS + +F + G L
Sbjct: 7 VLLSLLLLLGPAVPQENQDGRYSLTYIYTG----LSKHVEDVPAF--------QALGSLN 54
Query: 61 DLQTHGWDTV------LGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQ 114
DLQ +++ +G R ++ Q K + +F ++ S G
Sbjct: 55 DLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGS 114
Query: 115 FQLEYPFEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGI--SWEP-SPGAGIRAQNICKV 171
L+ F +I A F Y G D++ F +W P P A I Q +
Sbjct: 115 HVLQGRFGCEIENNRSSGA---FWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQK-WEA 170
Query: 172 LNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCH 231
Y+ + ++ L CP L ++ ++ L R+ P ++ +PG + +L C
Sbjct: 171 EPVYV---QRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKK-KLKCL 226
Query: 232 VSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSS 291
FYP + V W R + Q RGDVL N + T+ + V + A SC V+HSS
Sbjct: 227 AYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSS 286
Query: 292 LGGHDLIIHW 301
L L++ W
Sbjct: 287 L-AQPLVVPW 295
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 57.8 bits (138), Expect = 2e-08
Identities = 59/229 (25%), Positives = 98/229 (42%), Gaps = 26/229 (11%)
Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
+Q ++GC + L AY G D+++ SW A ++ R L
Sbjct: 119 LQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTA-------ADTAAQITQRKL 171
Query: 177 DIK---EILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVS 233
+ E L++ L TC +L +E G+ L+R P+ ++ P L C
Sbjct: 172 EAARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPL-SDHEATLRCWAL 230
Query: 234 GFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSL 292
GFYP + + W R GE + + T+ + P D T+ A + V +G+ +C ++H L
Sbjct: 231 GFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGL 290
Query: 293 GGHDLIIHWGGYS-----IFLILICLTVIVTLVIL--VVVDSRLKKQSS 334
L + W S I I+ L V+V L +L VV +++SS
Sbjct: 291 -QEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSS 338
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 54.3 bits (129), Expect = 2e-07
Identities = 63/261 (24%), Positives = 106/261 (40%), Gaps = 34/261 (13%)
Query: 87 KQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFEIQILAGCRMNAPQIFLN----MAY 142
++ L+NL+ + Q+ AG L Q + GC + L AY
Sbjct: 99 RESLRNLRGYYN----------QSEAGSHTL------QSMYGCDVGPDGRLLRGHDQYAY 142
Query: 143 QGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEA 200
G D+++ SW + A Q + E ++ L C +L +E
Sbjct: 143 DGKDYIALNEDLRSWTAADTAAQITQRKWEAARE----AEQRRAYLEGECVEWLRRYLEN 198
Query: 201 GESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDV 259
G+ +L+R P+ ++ P L C GFYP + + W R GE + + T+ +
Sbjct: 199 GKDKLERADPPKTHVTHHPI-SDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVET 257
Query: 260 LPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYS-----IFLILICLT 314
P D T+ A + V +GE +C V+H L L + W S I I+ L
Sbjct: 258 RPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGL-PKPLTLRWEPSSQSTVPIVGIVAGLA 316
Query: 315 VIVTLVILVVVDSRLKKQSSN 335
V+ +VI VV + + ++ S+
Sbjct: 317 VLAVVVIGAVVAAVMCRRKSS 337
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 52.4 bits (124), Expect = 7e-07
Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 9/110 (8%)
Query: 201 GESELKRKVKPEAWLSCGPSPGPGRLQ----LVCHVSGFYPKPVWVMW-MRGEQEQRGTQ 255
G L+R+V+P +S PS G LQ LVCHV+ FYP + V W + G++E G
Sbjct: 114 GPMTLQRRVQPRVNVS--PSK-KGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVV 170
Query: 256 RGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYS 305
+++ N D T+ + L++ + +C+V+H+SL + + W S
Sbjct: 171 STNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDS-PVTVEWKAQS 219
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 50.1 bits (118), Expect = 3e-06
Identities = 49/191 (25%), Positives = 77/191 (40%), Gaps = 18/191 (9%)
Query: 109 QASAGQFQLEYPFEIQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAG 162
Q+ AG L++ + GC + FL AY G D+L+ SW A
Sbjct: 108 QSEAGSHTLQW------MHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWT----AV 157
Query: 163 IRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPG 222
A I + + E ++ L TC +L +E G+ L P+ ++ P
Sbjct: 158 DTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPI-S 216
Query: 223 PGRLQLVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAA 281
L C GFYP + + W + GE + T+ + P D T+ A + V +GE
Sbjct: 217 DHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQ 276
Query: 282 GLSCRVKHSSL 292
+C V+H L
Sbjct: 277 RYTCHVQHEGL 287
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 48.9 bits (115), Expect = 8e-06
Identities = 30/118 (25%), Positives = 59/118 (50%), Gaps = 7/118 (5%)
Query: 228 LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 285
L C +YP+ + + W++ +Q + + + DVLPN D T+ TL V GE +C
Sbjct: 43 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102
Query: 286 RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
+V+H L LI+ W G + ++ + V V ++ + ++ L+K+ ++ +
Sbjct: 103 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 159
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 48.9 bits (115), Expect = 8e-06
Identities = 30/118 (25%), Positives = 59/118 (50%), Gaps = 7/118 (5%)
Query: 228 LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 285
L C +YP+ + + W++ +Q + + + DVLPN D T+ TL V GE +C
Sbjct: 131 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 190
Query: 286 RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
+V+H L LI+ W G + ++ + V V ++ + ++ L+K+ ++ +
Sbjct: 191 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 247
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,026,709
Number of Sequences: 37866
Number of extensions: 744192
Number of successful extensions: 2111
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1965
Number of HSP's gapped (non-prelim): 115
length of query: 388
length of database: 18,247,518
effective HSP length: 104
effective length of query: 284
effective length of database: 14,309,454
effective search space: 4063884936
effective search space used: 4063884936
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.