Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 110618240

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]
         (388 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]          804   0.0  
gi|110618230 CD1E antigen isoform b precursor [Homo sapiens]          770   0.0  
gi|110618234 CD1E antigen isoform d precursor [Homo sapiens]          603   e-173
gi|110618232 CD1E antigen isoform c precursor [Homo sapiens]          562   e-160
gi|4502649 CD1D antigen precursor [Homo sapiens]                      363   e-100
gi|4502645 CD1B antigen precursor [Homo sapiens]                      358   5e-99
gi|110618224 CD1A antigen precursor [Homo sapiens]                    357   1e-98
gi|110618236 CD1E antigen isoform e precursor [Homo sapiens]          345   3e-95
gi|110618227 CD1C antigen precursor [Homo sapiens]                    345   3e-95
gi|110618238 CD1E antigen isoform f precursor [Homo sapiens]          137   1e-32
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H...    74   3e-13
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom...    74   3e-13
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa...    66   5e-11
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa...    65   1e-10
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap...    65   1e-10
gi|4504417 major histocompatibility complex, class I-related [Ho...    64   2e-10
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi...    63   5e-10
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa...    62   7e-10
gi|149158702 major histocompatibility complex, class I, F isofor...    61   2e-09
gi|149158698 major histocompatibility complex, class I, F isofor...    61   2e-09
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa...    61   2e-09
gi|4504415 major histocompatibility complex, class I, G precurso...    61   2e-09
gi|24797067 major histocompatibility complex, class I, A precurs...    61   2e-09
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]                 60   4e-09
gi|52630342 major histocompatibility complex, class I, C precurs...    58   2e-08
gi|17986001 major histocompatibility complex, class I, B precurs...    54   2e-07
gi|24797076 major histocompatibility complex, class II, DP beta ...    52   7e-07
gi|62912479 major histocompatibility complex, class I, E precurs...    50   3e-06
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s...    49   8e-06
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa...    49   8e-06

>gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]
          Length = 388

 Score =  804 bits (2076), Expect = 0.0
 Identities = 388/388 (100%), Positives = 388/388 (100%)

Query: 1   MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
           MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG
Sbjct: 1   MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60

Query: 61  DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
           DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP
Sbjct: 61  DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120

Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
           FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE
Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180

Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
           ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV
Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240

Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300
           WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH
Sbjct: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300

Query: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360
           WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS
Sbjct: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360

Query: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388
           RHQFCLAQVSWIKNRVLKKWKTRLNQLW
Sbjct: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388


>gi|110618230 CD1E antigen isoform b precursor [Homo sapiens]
          Length = 376

 Score =  770 bits (1989), Expect = 0.0
 Identities = 376/388 (96%), Positives = 376/388 (96%), Gaps = 12/388 (3%)

Query: 1   MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
           MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG
Sbjct: 1   MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60

Query: 61  DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
           DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP
Sbjct: 61  DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120

Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
           FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE
Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180

Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
           ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV
Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240

Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300
           WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH
Sbjct: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300

Query: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360
           WGGYSIFLILICLTVIVTLVILVVVDSRLKKQ            SPVFLMGANTQDTKNS
Sbjct: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQ------------SPVFLMGANTQDTKNS 348

Query: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388
           RHQFCLAQVSWIKNRVLKKWKTRLNQLW
Sbjct: 349 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 376


>gi|110618234 CD1E antigen isoform d precursor [Homo sapiens]
          Length = 321

 Score =  603 bits (1556), Expect = e-173
 Identities = 310/388 (79%), Positives = 315/388 (81%), Gaps = 67/388 (17%)

Query: 1   MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
           MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG
Sbjct: 1   MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60

Query: 61  DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
           DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP
Sbjct: 61  DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120

Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
           FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE
Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180

Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
           ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV
Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240

Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIH 300
           WVMWMR                                              GG+ + + 
Sbjct: 241 WVMWMR----------------------------------------------GGYSIFL- 253

Query: 301 WGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTKNS 360
                  LI + + V  TLVILVVVDSRLKKQ            SPVFLMGANTQDTKNS
Sbjct: 254 ------ILICLTVIV--TLVILVVVDSRLKKQ------------SPVFLMGANTQDTKNS 293

Query: 361 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 388
           RHQFCLAQVSWIKNRVLKKWKTRLNQLW
Sbjct: 294 RHQFCLAQVSWIKNRVLKKWKTRLNQLW 321


>gi|110618232 CD1E antigen isoform c precursor [Homo sapiens]
          Length = 290

 Score =  562 bits (1449), Expect = e-160
 Identities = 267/269 (99%), Positives = 269/269 (100%)

Query: 1   MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
           MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG
Sbjct: 1   MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60

Query: 61  DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
           DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP
Sbjct: 61  DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120

Query: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180
           FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE
Sbjct: 121 FEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIKE 180

Query: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240
           ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV
Sbjct: 181 ILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPV 240

Query: 241 WVMWMRGEQEQRGTQRGDVLPNADETWYL 269
           WVMWMRGEQEQRGTQRGDVLPNADETW++
Sbjct: 241 WVMWMRGEQEQRGTQRGDVLPNADETWWI 269


>gi|4502649 CD1D antigen precursor [Homo sapiens]
          Length = 335

 Score =  363 bits (932), Expect = e-100
 Identities = 185/342 (54%), Positives = 234/342 (68%), Gaps = 15/342 (4%)

Query: 3   LLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGDL 62
           LLFLL   L     +   PQ L             R LQ SSFAN SW  ++G  WLG+L
Sbjct: 4   LLFLLLWALLQAWGSAEVPQRL----------FPLRCLQISSFANSSWTRTDGLAWLGEL 53

Query: 63  QTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFE 122
           QTH W     T+R LKPWS G FS Q+ + LQ +F++Y  SF + V+  A   +L YP E
Sbjct: 54  QTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLE 113

Query: 123 IQILAGCRM---NAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIK 179
           +Q+ AGC +   NA   F ++A+QG D LSFQG SWEP+  A +      +VLN+    +
Sbjct: 114 LQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTR 173

Query: 180 EILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKP 239
           E +Q LL  TCP+F++GL+E+G+SELK++VKP+AWLS GPSPGPGRL LVCHVSGFYPKP
Sbjct: 174 ETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKP 233

Query: 240 VWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLII 299
           VWV WMRGEQEQ+GTQ GD+LPNADETWYLRATLDV AGEAAGLSCRVKHSSL G D+++
Sbjct: 234 VWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVL 293

Query: 300 HWGGYSIFLILICLTVIVTLVILVVV--DSRLKKQSSNKNIL 339
           +WGG    + LI L V+  L+ L++V   SR K+Q+S + +L
Sbjct: 294 YWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL 335


>gi|4502645 CD1B antigen precursor [Homo sapiens]
          Length = 333

 Score =  358 bits (919), Expect = 5e-99
 Identities = 183/341 (53%), Positives = 236/341 (69%), Gaps = 12/341 (3%)

Query: 1   MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
           MLLL      +  PG N        S H A +   SF ++QTSSF N +WA ++GSGWL 
Sbjct: 1   MLLLPFQLLAVLFPGGN--------SEH-AFQGPTSFHVIQTSSFTNSTWAQTQGSGWLD 51

Query: 61  DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
           DLQ HGWD+  GT  FLKPWS GNFS +E+  L+ +F++Y   F + VQ  AG FQ++YP
Sbjct: 52  DLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYP 111

Query: 121 FEIQILAGCRMN---APQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLD 177
           FEIQ +AGC ++   A   FL  A  G DFLS +  S  PSP  G RAQ  C ++ +Y  
Sbjct: 112 FEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQG 171

Query: 178 IKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYP 237
           I E ++ LL  TCPR+L G++ AG+++L+R+VKPEAWLS GPSPGPGRLQLVCHVSGFYP
Sbjct: 172 IMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYP 231

Query: 238 KPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDL 297
           KPVWVMWMRGEQEQ+GTQ GD+LPNA+ TWYLRATLDVA GEAAGLSCRVKHSSL G D+
Sbjct: 232 KPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDI 291

Query: 298 IIHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNI 338
           I++W   +    ++   ++ +L++L+ +     ++ S +NI
Sbjct: 292 ILYWRNPTSIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNI 332


>gi|110618224 CD1A antigen precursor [Homo sapiens]
          Length = 327

 Score =  357 bits (915), Expect = 1e-98
 Identities = 181/325 (55%), Positives = 230/325 (70%), Gaps = 14/325 (4%)

Query: 3   LLFLLFEGLCC-PGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
           +LFLL   L   PG+  A            +E LSF +   +SF NHSW  +  SGWL D
Sbjct: 1   MLFLLLPLLAVLPGDGNAD---------GLKEPLSFHVTWIASFYNHSWKQNLVSGWLSD 51

Query: 62  LQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPF 121
           LQTH WD+   TI FL PWS GNFS +E K L++LF++      + ++  A + Q EYPF
Sbjct: 52  LQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPF 111

Query: 122 EIQILAGCRMNAPQI---FLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDI 178
           EIQ+  GC +++ ++   FL +AYQGSDF+SFQ  SW P P AG  A++ CKVLN+    
Sbjct: 112 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHE 171

Query: 179 KEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPK 238
            +I  +LL  TCPRF+ GL++AG++ L+R+VKPEAWLS GPSPGPG LQLVCHVSGFYPK
Sbjct: 172 NDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPK 231

Query: 239 PVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLI 298
           PVWVMWMRGEQEQ+GTQRGD+LP+AD TWYLRATL+VAAGEAA LSCRVKHSSL G D++
Sbjct: 232 PVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIV 291

Query: 299 IHWGGYSIFLILICLTVIVTLVILV 323
           ++W  +S    +I L VIV L++L+
Sbjct: 292 LYWEHHSSVGFII-LAVIVPLLLLI 315


>gi|110618236 CD1E antigen isoform e precursor [Homo sapiens]
          Length = 187

 Score =  345 bits (886), Expect = 3e-95
 Identities = 168/180 (93%), Positives = 168/180 (93%), Gaps = 12/180 (6%)

Query: 209 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 268
           VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY
Sbjct: 20  VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79

Query: 269 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 328
           LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR
Sbjct: 80  LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 139

Query: 329 LKKQSSNKNILSPHTPSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 388
           LKKQ            SPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW
Sbjct: 140 LKKQ------------SPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 187



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 21/24 (87%), Positives = 22/24 (91%), Gaps = 1/24 (4%)

Query: 1  MLLLFLLFEGLCCPGENTAA-PQA 23
          MLLLFLLFEGLCCPGENTA  P+A
Sbjct: 1  MLLLFLLFEGLCCPGENTAVKPEA 24


>gi|110618227 CD1C antigen precursor [Homo sapiens]
          Length = 333

 Score =  345 bits (886), Expect = 3e-95
 Identities = 175/343 (51%), Positives = 230/343 (67%), Gaps = 14/343 (4%)

Query: 1   MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
           ML L  L   L  PG + A          A++E +SF ++Q  SF N SWA  +GSGWL 
Sbjct: 1   MLFLQFLLLALLLPGGDNAD---------ASQEHVSFHVIQIFSFVNQSWARGQGSGWLD 51

Query: 61  DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
           +LQTHGWD+  GTI FL  WS GNFS +EL +L+ LF+ Y     + +Q  A Q   +YP
Sbjct: 52  ELQTHGWDSESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYP 111

Query: 121 FEIQILAGCRMNA---PQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLN-RYL 176
           FE+Q+ AGC +++   P+ F  +A+ G D LSFQ  +W PSPG G  AQ++C +LN +Y 
Sbjct: 112 FEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYE 171

Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
            + E + +L+  TCPRFL GL++AG+  + R+V+PEAWLS  PS G G+L LVCH SGFY
Sbjct: 172 GVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFY 231

Query: 237 PKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHD 296
           PKPVWV WMR EQEQ GT+ GD+LPNAD TWYL+  L+VA+ E AGLSCRV+HSSLGG D
Sbjct: 232 PKPVWVTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQD 291

Query: 297 LIIHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
           +I++W G+   +  I L VIV LVIL+V+    KK  S ++IL
Sbjct: 292 IILYW-GHHFSMNWIALVVIVPLVILIVLVLWFKKHCSYQDIL 333


>gi|110618238 CD1E antigen isoform f precursor [Homo sapiens]
          Length = 101

 Score =  137 bits (346), Expect = 1e-32
 Identities = 59/61 (96%), Positives = 61/61 (100%)

Query: 209 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 268
           VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETW+
Sbjct: 20  VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWW 79

Query: 269 L 269
           +
Sbjct: 80  I 80



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 21/24 (87%), Positives = 22/24 (91%), Gaps = 1/24 (4%)

Query: 1  MLLLFLLFEGLCCPGENTAA-PQA 23
          MLLLFLLFEGLCCPGENTA  P+A
Sbjct: 1  MLLLFLLFEGLCCPGENTAVKPEA 24


>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
           sapiens]
          Length = 365

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 83/304 (27%), Positives = 126/304 (41%), Gaps = 47/304 (15%)

Query: 2   LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
           LLLFLL      PG   A       YHL A   +S     T +F    W     SGWLG 
Sbjct: 13  LLLFLL------PGSLGAESHLSLLYHLTA---VSSPAPGTPAF----WV----SGWLGP 55

Query: 62  LQTHGWDTVLGTIRFLKPWSHGN----FSKQELKNLQSLFQLYFHSFIQIVQASAGQFQL 117
            Q   ++++ G       W   N    + ++E  +L+   +L+  +F    +A  G+   
Sbjct: 56  QQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGGKG-- 109

Query: 118 EYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSFQ------GISWEPSPGAGIRAQNI 168
             P+ +Q L GC +   N        A  G +F++F       G  W  +     R Q  
Sbjct: 110 --PYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQ 167

Query: 169 CKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQL 228
            K  N+ L       + L  +CP  L   +E G   L+ K  P   L   PS  PG   L
Sbjct: 168 DKAANKEL-------TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVL 219

Query: 229 VCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVK 288
            C    FYP  + + ++R      GT +GD  PN+D +++  ++L V +G+     C V+
Sbjct: 220 TCSAFSFYPPELQLRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQ 278

Query: 289 HSSL 292
           H+ L
Sbjct: 279 HAGL 282


>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
           sapiens]
          Length = 365

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 83/304 (27%), Positives = 126/304 (41%), Gaps = 47/304 (15%)

Query: 2   LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
           LLLFLL      PG   A       YHL A   +S     T +F    W     SGWLG 
Sbjct: 13  LLLFLL------PGSLGAESHLSLLYHLTA---VSSPAPGTPAF----WV----SGWLGP 55

Query: 62  LQTHGWDTVLGTIRFLKPWSHGN----FSKQELKNLQSLFQLYFHSFIQIVQASAGQFQL 117
            Q   ++++ G       W   N    + ++E  +L+   +L+  +F    +A  G+   
Sbjct: 56  QQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGGKG-- 109

Query: 118 EYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSFQ------GISWEPSPGAGIRAQNI 168
             P+ +Q L GC +   N        A  G +F++F       G  W  +     R Q  
Sbjct: 110 --PYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQ 167

Query: 169 CKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQL 228
            K  N+ L       + L  +CP  L   +E G   L+ K  P   L   PS  PG   L
Sbjct: 168 DKAANKEL-------TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVL 219

Query: 229 VCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVK 288
            C    FYP  + + ++R      GT +GD  PN+D +++  ++L V +G+     C V+
Sbjct: 220 TCSAFSFYPPELQLRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQ 278

Query: 289 HSSL 292
           H+ L
Sbjct: 279 HAGL 282


>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
           sapiens]
          Length = 260

 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 58/246 (23%), Positives = 109/246 (44%), Gaps = 17/246 (6%)

Query: 105 IQIVQASAGQFQLEYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSF--QGISWEPSP 159
           + ++Q +  Q +L     +Q++ GC M   N+ + +    Y G D L F    + W    
Sbjct: 12  LMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWR--- 68

Query: 160 GAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGP 219
            A  RA        R+       ++ L   CP  L  L+E G   L ++V P   ++   
Sbjct: 69  AAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHV 128

Query: 220 SPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAA 277
           +     L+  C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  
Sbjct: 129 TSSVTTLR--CRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPP 186

Query: 278 GEAAGLSCRVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQS 333
           GE    +C+V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+ 
Sbjct: 187 GEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 245

Query: 334 SNKNIL 339
            ++  +
Sbjct: 246 GSRGAM 251


>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
           sapiens]
          Length = 325

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 62/273 (22%), Positives = 112/273 (41%), Gaps = 18/273 (6%)

Query: 79  PWSHGNFSKQELKNLQSLFQLYFHSF-IQIVQASAGQFQLEYPFEIQILAGCRM---NAP 134
           PW     S Q    L    + + H F +            +    +Q++ GC M   N+ 
Sbjct: 50  PWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNST 109

Query: 135 QIFLNMAYQGSDFLSF--QGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPR 192
           + +    Y G D L F    + W     A  RA        R+       ++ L   CP 
Sbjct: 110 EGYWKYGYDGQDHLEFCPDTLDWR---AAEPRAWPTKLEWERHKIRARQNRAYLERDCPA 166

Query: 193 FLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--E 250
            L  L+E G   L ++V P   ++   +     L+  C    +YP+ + + W++ +Q  +
Sbjct: 167 QLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRALNYYPQNITMKWLKDKQPMD 224

Query: 251 QRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHW----GGYSI 306
            +  +  DVLPN D T+    TL V  GE    +C+V+H  L    LI+ W     G  +
Sbjct: 225 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLV 283

Query: 307 FLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
             ++  + V V ++ + ++   L+K+  ++  +
Sbjct: 284 IGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316


>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
           sapiens]
          Length = 348

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 62/273 (22%), Positives = 112/273 (41%), Gaps = 18/273 (6%)

Query: 79  PWSHGNFSKQELKNLQSLFQLYFHSF-IQIVQASAGQFQLEYPFEIQILAGCRM---NAP 134
           PW     S Q    L    + + H F +            +    +Q++ GC M   N+ 
Sbjct: 73  PWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNST 132

Query: 135 QIFLNMAYQGSDFLSF--QGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPR 192
           + +    Y G D L F    + W     A  RA        R+       ++ L   CP 
Sbjct: 133 EGYWKYGYDGQDHLEFCPDTLDWR---AAEPRAWPTKLEWERHKIRARQNRAYLERDCPA 189

Query: 193 FLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--E 250
            L  L+E G   L ++V P   ++   +     L+  C    +YP+ + + W++ +Q  +
Sbjct: 190 QLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRALNYYPQNITMKWLKDKQPMD 247

Query: 251 QRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHW----GGYSI 306
            +  +  DVLPN D T+    TL V  GE    +C+V+H  L    LI+ W     G  +
Sbjct: 248 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLV 306

Query: 307 FLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
             ++  + V V ++ + ++   L+K+  ++  +
Sbjct: 307 IGVISGIAVFVVILFIGILFIILRKRQGSRGAM 339


>gi|4504417 major histocompatibility complex, class I-related [Homo
           sapiens]
          Length = 341

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 59/257 (22%), Positives = 110/257 (42%), Gaps = 21/257 (8%)

Query: 79  PWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFEIQILAGCRM---NAPQ 135
           PW   N +    +    L + +   F   ++     +        Q + GC +    +  
Sbjct: 70  PWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTT 129

Query: 136 IFLNMAYQGSDFLSFQG--ISWEPSPGAGIRAQNICKVLNRYLDIK--EIL--QSLLGHT 189
            FL  AY G DFL F    +SW       +   N+   + +  +    E+L  ++ L   
Sbjct: 130 GFLQYAYDGQDFLIFNKDTLSW-------LAVDNVAHTIKQAWEANQHELLYQKNWLEEE 182

Query: 190 CPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMR-GE 248
           C  +L   +E G+  L+R   P   ++      PG   L C   GFYP  +++ WM+ GE
Sbjct: 183 CIAWLKRFLEYGKDTLQRTEPPLVRVN-RKETFPGVTALFCKAHGFYPPEIYMTWMKNGE 241

Query: 249 QEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFL 308
           +  +    GD+LP+ D T+   A++++    +   SC V+H    G  +++     S  +
Sbjct: 242 EIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHC---GVHMVLQVPQESETI 298

Query: 309 ILICLTVIVTLVILVVV 325
            L+   V  ++V+++V+
Sbjct: 299 PLVMKAVSGSIVLVIVL 315


>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
           sapiens]
          Length = 366

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 61/224 (27%), Positives = 99/224 (44%), Gaps = 16/224 (7%)

Query: 123 IQILAGCRMNAPQIFLNM----AYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
           +Q++ GC +     FL      AY G D+++      SW     A   A  I K      
Sbjct: 132 LQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWT----AADTAAQITKRKREAA 187

Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
              E  ++ L   C   L   +E G+  L R   P+A ++  P      + L C   GFY
Sbjct: 188 GAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPI-SEREVTLRCWALGFY 246

Query: 237 PKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGH 295
           P+ + + W R GE + +  +  +  P+ D T+   A L V +GE    +CRV+H  L   
Sbjct: 247 PEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGL-QE 305

Query: 296 DLIIHW-GGYSIFLILICLTVIVTLVILVVVDSRL--KKQSSNK 336
            L + W    + FLI+  +  +V LV+ +V  + +  KK+S  +
Sbjct: 306 PLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKRSGRE 349


>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
           sapiens]
          Length = 246

 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 57/246 (23%), Positives = 104/246 (42%), Gaps = 31/246 (12%)

Query: 105 IQIVQASAGQFQLEYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSF--QGISWEPSP 159
           + ++Q +  Q +L     +Q++ GC M   N+ + +    Y G D L F    + W    
Sbjct: 12  LMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWR--- 68

Query: 160 GAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGP 219
            A  RA        R+       ++ L   CP  L  L+E G   L ++V          
Sbjct: 69  AAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT-------- 120

Query: 220 SPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAA 277
                   L C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  
Sbjct: 121 --------LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPP 172

Query: 278 GEAAGLSCRVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQS 333
           GE    +C+V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+ 
Sbjct: 173 GEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 231

Query: 334 SNKNIL 339
            ++  +
Sbjct: 232 GSRGAM 237


>gi|149158702 major histocompatibility complex, class I, F isoform 1
           precursor [Homo sapiens]
          Length = 442

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 60/236 (25%), Positives = 94/236 (39%), Gaps = 27/236 (11%)

Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
           +Q + GC M      L      AY G D++S      SW         A  + ++  R+ 
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTA-------ADTVAQITQRFY 168

Query: 177 DIKEILQSL---LGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVS 233
           + +E  +     L   C   L   +E G+  L+R   P+A ++  P        L C   
Sbjct: 169 EAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWAL 227

Query: 234 GFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSL 292
           GFYP  + + W R GE++ + T+  +  P  D T+   A + V  GE    +C V+H  L
Sbjct: 228 GFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGL 287

Query: 293 GGHDLIIHWGG--------YSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILS 340
               LI+ W            I   L+ L  +VT  ++  V  R K    N+   S
Sbjct: 288 -PQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYS 342


>gi|149158698 major histocompatibility complex, class I, F isoform 2
           precursor [Homo sapiens]
          Length = 346

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 60/236 (25%), Positives = 94/236 (39%), Gaps = 27/236 (11%)

Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
           +Q + GC M      L      AY G D++S      SW         A  + ++  R+ 
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTA-------ADTVAQITQRFY 168

Query: 177 DIKEILQSL---LGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVS 233
           + +E  +     L   C   L   +E G+  L+R   P+A ++  P        L C   
Sbjct: 169 EAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWAL 227

Query: 234 GFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSL 292
           GFYP  + + W R GE++ + T+  +  P  D T+   A + V  GE    +C V+H  L
Sbjct: 228 GFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGL 287

Query: 293 GGHDLIIHWGG--------YSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILS 340
               LI+ W            I   L+ L  +VT  ++  V  R K    N+   S
Sbjct: 288 -PQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYS 342


>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
           sapiens]
          Length = 334

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 61/273 (22%), Positives = 107/273 (39%), Gaps = 32/273 (11%)

Query: 79  PWSHGNFSKQELKNLQSLFQLYFHSF-IQIVQASAGQFQLEYPFEIQILAGCRM---NAP 134
           PW     S Q    L    + + H F +            +    +Q++ GC M   N+ 
Sbjct: 73  PWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNST 132

Query: 135 QIFLNMAYQGSDFLSF--QGISWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPR 192
           + +    Y G D L F    + W     A  RA        R+       ++ L   CP 
Sbjct: 133 EGYWKYGYDGQDHLEFCPDTLDWR---AAEPRAWPTKLEWERHKIRARQNRAYLERDCPA 189

Query: 193 FLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ--E 250
            L  L+E G   L ++V                  L C    +YP+ + + W++ +Q  +
Sbjct: 190 QLQQLLELGRGVLDQQVTT----------------LRCRALNYYPQNITMKWLKDKQPMD 233

Query: 251 QRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHW----GGYSI 306
            +  +  DVLPN D T+    TL V  GE    +C+V+H  L    LI+ W     G  +
Sbjct: 234 AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL-DQPLIVIWEPSPSGTLV 292

Query: 307 FLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
             ++  + V V ++ + ++   L+K+  ++  +
Sbjct: 293 IGVISGIAVFVVILFIGILFIILRKRQGSRGAM 325


>gi|4504415 major histocompatibility complex, class I, G precursor
           [Homo sapiens]
          Length = 338

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 55/210 (26%), Positives = 93/210 (44%), Gaps = 14/210 (6%)

Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
           +Q + GC + +    L      AY G D+L+      SW  +  A   ++  C+  N   
Sbjct: 119 LQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN--- 175

Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
            + E  ++ L  TC  +L   +E G+  L+R   P+  ++  P        L C   GFY
Sbjct: 176 -VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPV-FDYEATLRCWALGFY 233

Query: 237 PKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGH 295
           P  + + W R GE + +  +  +  P  D T+   A + V +GE    +C V+H  L   
Sbjct: 234 PAEIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL-PE 292

Query: 296 DLIIHWGGYSIFLILICLTVIVTLVILVVV 325
            L++ W   S+  I I + ++  LV+L  V
Sbjct: 293 PLMLRWKQSSLPTIPI-MGIVAGLVVLAAV 321


>gi|24797067 major histocompatibility complex, class I, A precursor
           [Homo sapiens]
          Length = 365

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 63/229 (27%), Positives = 96/229 (41%), Gaps = 22/229 (9%)

Query: 123 IQILAGCRMNAPQIFLNM----AYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
           IQI+ GC + +   FL      AY G D+++      SW     A   A  I K      
Sbjct: 119 IQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWT----AADMAAQITKRKWEAA 174

Query: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
              E L++ L  TC  +L   +E G+  L+R   P+  ++  P        L C   GFY
Sbjct: 175 HEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPI-SDHEATLRCWALGFY 233

Query: 237 PKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGH 295
           P  + + W R GE + + T+  +  P  D T+   A + V +GE    +C V+H  L   
Sbjct: 234 PAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL-PK 292

Query: 296 DLIIHWGGYS--------IFLILICLTVIVTLVILVVVDSRLKKQSSNK 336
            L + W   S        I   L+ L  ++T  ++  V  R +K S  K
Sbjct: 293 PLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWR-RKSSDRK 340


>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
          Length = 298

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 76/310 (24%), Positives = 121/310 (39%), Gaps = 30/310 (9%)

Query: 1   MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
           +LL  LL  G   P EN     +L   +      LS  +    +F        +  G L 
Sbjct: 7   VLLSLLLLLGPAVPQENQDGRYSLTYIYTG----LSKHVEDVPAF--------QALGSLN 54

Query: 61  DLQTHGWDTV------LGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQ 114
           DLQ   +++       +G  R ++         Q  K  + +F       ++    S G 
Sbjct: 55  DLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGS 114

Query: 115 FQLEYPFEIQILAGCRMNAPQIFLNMAYQGSDFLSFQGI--SWEP-SPGAGIRAQNICKV 171
             L+  F  +I       A   F    Y G D++ F     +W P  P A I  Q   + 
Sbjct: 115 HVLQGRFGCEIENNRSSGA---FWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQK-WEA 170

Query: 172 LNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCH 231
              Y+   +  ++ L   CP  L   ++  ++ L R+  P   ++   +PG  + +L C 
Sbjct: 171 EPVYV---QRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKK-KLKCL 226

Query: 232 VSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSS 291
              FYP  + V W R  + Q    RGDVL N + T+     + V   + A  SC V+HSS
Sbjct: 227 AYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSS 286

Query: 292 LGGHDLIIHW 301
           L    L++ W
Sbjct: 287 L-AQPLVVPW 295


>gi|52630342 major histocompatibility complex, class I, C precursor
           [Homo sapiens]
          Length = 366

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 59/229 (25%), Positives = 98/229 (42%), Gaps = 26/229 (11%)

Query: 123 IQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYL 176
           +Q ++GC +      L      AY G D+++      SW         A    ++  R L
Sbjct: 119 LQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTA-------ADTAAQITQRKL 171

Query: 177 DIK---EILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVS 233
           +     E L++ L  TC  +L   +E G+  L+R   P+  ++  P        L C   
Sbjct: 172 EAARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPL-SDHEATLRCWAL 230

Query: 234 GFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSL 292
           GFYP  + + W R GE + + T+  +  P  D T+   A + V +G+    +C ++H  L
Sbjct: 231 GFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGL 290

Query: 293 GGHDLIIHWGGYS-----IFLILICLTVIVTLVIL--VVVDSRLKKQSS 334
               L + W   S     I  I+  L V+V L +L  VV     +++SS
Sbjct: 291 -QEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSS 338


>gi|17986001 major histocompatibility complex, class I, B precursor
           [Homo sapiens]
          Length = 362

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 63/261 (24%), Positives = 106/261 (40%), Gaps = 34/261 (13%)

Query: 87  KQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFEIQILAGCRMNAPQIFLN----MAY 142
           ++ L+NL+  +           Q+ AG   L      Q + GC +      L      AY
Sbjct: 99  RESLRNLRGYYN----------QSEAGSHTL------QSMYGCDVGPDGRLLRGHDQYAY 142

Query: 143 QGSDFLSFQGI--SWEPSPGAGIRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEA 200
            G D+++      SW  +  A    Q   +         E  ++ L   C  +L   +E 
Sbjct: 143 DGKDYIALNEDLRSWTAADTAAQITQRKWEAARE----AEQRRAYLEGECVEWLRRYLEN 198

Query: 201 GESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDV 259
           G+ +L+R   P+  ++  P        L C   GFYP  + + W R GE + + T+  + 
Sbjct: 199 GKDKLERADPPKTHVTHHPI-SDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVET 257

Query: 260 LPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYS-----IFLILICLT 314
            P  D T+   A + V +GE    +C V+H  L    L + W   S     I  I+  L 
Sbjct: 258 RPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGL-PKPLTLRWEPSSQSTVPIVGIVAGLA 316

Query: 315 VIVTLVILVVVDSRLKKQSSN 335
           V+  +VI  VV + + ++ S+
Sbjct: 317 VLAVVVIGAVVAAVMCRRKSS 337


>gi|24797076 major histocompatibility complex, class II, DP beta 1
           precursor [Homo sapiens]
          Length = 258

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 9/110 (8%)

Query: 201 GESELKRKVKPEAWLSCGPSPGPGRLQ----LVCHVSGFYPKPVWVMW-MRGEQEQRGTQ 255
           G   L+R+V+P   +S  PS   G LQ    LVCHV+ FYP  + V W + G++E  G  
Sbjct: 114 GPMTLQRRVQPRVNVS--PSK-KGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVV 170

Query: 256 RGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYS 305
             +++ N D T+ +   L++   +    +C+V+H+SL    + + W   S
Sbjct: 171 STNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDS-PVTVEWKAQS 219


>gi|62912479 major histocompatibility complex, class I, E precursor
           [Homo sapiens]
          Length = 358

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 49/191 (25%), Positives = 77/191 (40%), Gaps = 18/191 (9%)

Query: 109 QASAGQFQLEYPFEIQILAGCRMNAPQIFLN----MAYQGSDFLSFQGI--SWEPSPGAG 162
           Q+ AG   L++      + GC +     FL      AY G D+L+      SW     A 
Sbjct: 108 QSEAGSHTLQW------MHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWT----AV 157

Query: 163 IRAQNICKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPG 222
             A  I +  +      E  ++ L  TC  +L   +E G+  L     P+  ++  P   
Sbjct: 158 DTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPI-S 216

Query: 223 PGRLQLVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAA 281
                L C   GFYP  + + W + GE   + T+  +  P  D T+   A + V +GE  
Sbjct: 217 DHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQ 276

Query: 282 GLSCRVKHSSL 292
             +C V+H  L
Sbjct: 277 RYTCHVQHEGL 287


>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
           sapiens]
          Length = 168

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 30/118 (25%), Positives = 59/118 (50%), Gaps = 7/118 (5%)

Query: 228 LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 285
           L C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  GE    +C
Sbjct: 43  LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102

Query: 286 RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
           +V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+  ++  +
Sbjct: 103 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 159


>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
           sapiens]
          Length = 256

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 30/118 (25%), Positives = 59/118 (50%), Gaps = 7/118 (5%)

Query: 228 LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 285
           L C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  GE    +C
Sbjct: 131 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 190

Query: 286 RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
           +V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+  ++  +
Sbjct: 191 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 247


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,026,709
Number of Sequences: 37866
Number of extensions: 744192
Number of successful extensions: 2111
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1965
Number of HSP's gapped (non-prelim): 115
length of query: 388
length of database: 18,247,518
effective HSP length: 104
effective length of query: 284
effective length of database: 14,309,454
effective search space: 4063884936
effective search space used: 4063884936
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press