BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] (977 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 1982 0.0 gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] 1460 0.0 gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 349 8e-96 gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 341 2e-93 gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 340 3e-93 gi|158303333 synaptopodin isoform B [Homo sapiens] 154 3e-37 gi|40353727 synaptopodin isoform A [Homo sapiens] 147 6e-35 gi|163965366 nascent polypeptide-associated complex alpha subuni... 115 3e-25 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 102 2e-21 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 99 2e-20 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 99 2e-20 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 99 2e-20 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 99 2e-20 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 94 5e-19 gi|55750053 atrophin-1 [Homo sapiens] 94 5e-19 gi|55750041 atrophin-1 [Homo sapiens] 94 5e-19 gi|160707881 formin 2 [Homo sapiens] 92 2e-18 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 90 9e-18 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 90 9e-18 gi|47132519 Ras association and pleckstrin homology domains 1 is... 88 3e-17 gi|18079216 CASK interacting protein 1 [Homo sapiens] 87 6e-17 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 86 2e-16 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 82 3e-15 gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 79 2e-14 gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 79 2e-14 gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 79 2e-14 gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 79 2e-14 gi|118402590 myosin XV [Homo sapiens] 78 4e-14 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 78 4e-14 gi|116284392 mucin 2 precursor [Homo sapiens] 77 6e-14 >gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] Length = 977 Score = 1982 bits (5135), Expect = 0.0 Identities = 977/977 (100%), Positives = 977/977 (100%) Query: 1 MGAEEEVLVTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVS 60 MGAEEEVLVTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVS Sbjct: 1 MGAEEEVLVTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVS 60 Query: 61 CTNLSHASAMSLIDASGNQLVLTVQRLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVP 120 CTNLSHASAMSLIDASGNQLVLTVQRLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVP Sbjct: 61 CTNLSHASAMSLIDASGNQLVLTVQRLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVP 120 Query: 121 QPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDS 180 QPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDS Sbjct: 121 QPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDS 180 Query: 181 PAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPH 240 PAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPH Sbjct: 181 PAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPH 240 Query: 241 PVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKK 300 PVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKK Sbjct: 241 PVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKK 300 Query: 301 RRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDME 360 RRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDME Sbjct: 301 RRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDME 360 Query: 361 LARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQ 420 LARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQ Sbjct: 361 LARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQ 420 Query: 421 SPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP 480 SPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP Sbjct: 421 SPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP 480 Query: 481 TTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRS 540 TTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRS Sbjct: 481 TTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRS 540 Query: 541 SGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPG 600 SGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPG Sbjct: 541 SGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPG 600 Query: 601 PGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLD 660 PGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLD Sbjct: 601 PGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLD 660 Query: 661 EKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPK 720 EKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPK Sbjct: 661 EKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPK 720 Query: 721 TPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGP 780 TPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGP Sbjct: 721 TPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGP 780 Query: 781 GLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP 840 GLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP Sbjct: 781 GLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP 840 Query: 841 KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAE 900 KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAE Sbjct: 841 KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAE 900 Query: 901 PLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRFSA 960 PLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRFSA Sbjct: 901 PLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRFSA 960 Query: 961 TRTGLQAHVWRPGAGHQ 977 TRTGLQAHVWRPGAGHQ Sbjct: 961 TRTGLQAHVWRPGAGHQ 977 >gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] Length = 753 Score = 1460 bits (3780), Expect = 0.0 Identities = 725/739 (98%), Positives = 727/739 (98%), Gaps = 6/739 (0%) Query: 239 PHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMF 298 P PV E Q + A+LQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMF Sbjct: 21 PDPVPE------LQDSFYAELQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMF 74 Query: 299 KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLD 358 KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLD Sbjct: 75 KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLD 134 Query: 359 MELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEG 418 MELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEG Sbjct: 135 MELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEG 194 Query: 419 LQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ 478 LQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ Sbjct: 195 LQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ 254 Query: 479 RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP 538 RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP Sbjct: 255 RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP 314 Query: 539 RSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPA 598 RSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPA Sbjct: 315 RSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPA 374 Query: 599 PGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQN 658 PGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQN Sbjct: 375 PGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQN 434 Query: 659 LDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMT 718 LDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMT Sbjct: 435 LDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMT 494 Query: 719 PKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTP 778 PKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTP Sbjct: 495 PKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTP 554 Query: 779 GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRA 838 GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRA Sbjct: 555 GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRA 614 Query: 839 TPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPT 898 TPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPT Sbjct: 615 TPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPT 674 Query: 899 AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRF 958 AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRF Sbjct: 675 AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRF 734 Query: 959 SATRTGLQAHVWRPGAGHQ 977 SATRTGLQAHVWRPGAGHQ Sbjct: 735 SATRTGLQAHVWRPGAGHQ 753 Score = 59.7 bits (143), Expect = 1e-08 Identities = 149/612 (24%), Positives = 206/612 (33%), Gaps = 124/612 (20%) Query: 92 PVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADG---- 147 P +P E VL P SP P P+P QPG P + G Sbjct: 199 PRAQSAPPEAAVLPP----SPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ 254 Query: 148 -PATQE---KPRRPRRR----GPTRPTPP---------------GAPPDEVYLSDSPAEP 184 P T +P P+R G P PP P +S SP+ P Sbjct: 255 RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP 314 Query: 185 APTIPGPPSQGDS----RVSSPSWEDGAALQPPPAEALLLP-------HGPLRPGPH-LI 232 + GP + S S P GA P P A + PLRP Sbjct: 315 RSS--GPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEA 372 Query: 233 PMVGP-VPHPVAEDLTTTYTQKAKQAKLQ--RAESLQEKSIKEAKTKCRTIASLLTAAPN 289 P GP P P + A+ LQ R +++ + K + + +PN Sbjct: 373 PAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKN-------SPN 425 Query: 290 PHSKGVLMFKKRRQRA------KKYTLVSFGAAA-----GTGAEEEDGVPPTSESELDEE 338 P ++ + RA + +S GA A GA +P + Sbjct: 426 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 485 Query: 339 AFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSE---VSGRGVQLFEQQR 395 A +T ++ P + + G G+ + E + GRG +LF +++ Sbjct: 486 APKTPPPMTPKT---PPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQ 542 Query: 396 QRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAP-VASPRPFQPGG 454 RAD E G GL PR+ S P LPPS +P + +P P Sbjct: 543 SRADRYVVE--------GTPGPGLGPRPRSPSPTPS---LPPSWKYSPNIRAPPPI---- 587 Query: 455 GAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQG 514 A P S F A P Q Q P T PK+ +L + P Q Sbjct: 588 -AYNPLLSPFFPQAARTLPKAQSQGPRAT--------PKQGIKALDFMRHQP-----YQL 633 Query: 515 PTPLPSFTSGVPSHAPV-SGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSA 573 T + F P+ P+ SGSP T R + R TP AP+P A P A Sbjct: 634 KTAMFCFDEVPPTPGPIASGSPKTAR------------VQEIRRFSTP--APQPTAEPLA 679 Query: 574 -AAMTSTASIFLSAPL----RPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEAR 628 + A+ L P+ SA +PAP P AP A AR A Sbjct: 680 PTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRF--SAT 737 Query: 629 RRGTRKQMFRPG 640 R G + ++RPG Sbjct: 738 RTGLQAHVWRPG 749 >gi|193083185 synaptopodin 2 isoform b [Homo sapiens] Length = 1093 Score = 349 bits (895), Expect = 8e-96 Identities = 290/832 (34%), Positives = 389/832 (46%), Gaps = 189/832 (22%) Query: 244 EDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQ 303 +D + + +A+ A+L+R+ESL EK +KEAK+KC++IA LLT APNP+SKGVLMFKKRR+ Sbjct: 343 KDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRR 402 Query: 304 RAKKYTLVSFGAA--AGTGAEEEDGVPP---------TSESELDEEAFSDARSLTN--QS 350 RA+KYTLVS+G EEE+G SESE+DEE SD T Sbjct: 403 RARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNF 462 Query: 351 DWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQEL----- 405 DWDS +D+E + + G + L + +G+G +F ++R+R D T + Sbjct: 463 DWDSGLVDIE-----KKLNRGDKMEM---LPDTTGKGALMFAKRRERMDQITAQKEEDKV 514 Query: 406 ----ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPR-----PFQPGGGA 456 +R + AA +GL++ Q E+ S + + P Q G Sbjct: 515 GGTPSREQDAAQT--DGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSG 572 Query: 457 PTPAPSI-----FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 511 + +I NR+A+PF PG Q T P +P R S PAPPP+ S Sbjct: 573 TSETANIQRMVPMNRTAKPF-PGSVNQPAT-------PFSPTRNMTSPIADFPAPPPY-S 623 Query: 512 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 571 + P P +F+ GV S P++G P P P PAP Sbjct: 624 AVTPPP-DAFSRGVSS--PIAGPAQPP--------------PWPQ-----------PAPW 655 Query: 572 SAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRG 631 S A ++ E ++R++RISVPA RTGILQEA+RR Sbjct: 656 SQPAFYDSS------------------------ERIASRDERISVPAKRTGILQEAKRRS 691 Query: 632 TRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG-GAESGPEEDALSLGAEACNFMQPV 690 T K MF +E K SPNPELLSL+QN + K G G +SGPEED LSLGAEACNFMQ Sbjct: 692 TTKPMFT--FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSS 749 Query: 691 GARSYKTLPHVTPKTPPPMAPK------TPPPMTPKTP---PPVAPK------------- 728 A+ KTPPP+APK + P+TP +P P VAP Sbjct: 750 SAKQ---------KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKG 800 Query: 729 -------------PPSR--------GLLDGLVNGAASSAGIPEP---------------- 751 PP+R G G AS P+P Sbjct: 801 TVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVG 860 Query: 752 -----PRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIR 806 P + GRG +LFAKRQSR ++YVV+ R+ SPTPSLP SWKYS N+R Sbjct: 861 PSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ--AHAARAQSPTPSLPASWKYSSNVR 918 Query: 807 APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQG---IKALDFMRHQPYQLKTAMFC 863 APPP+AYNP+ SP +P AA + +Q + K+G + ALD M+HQPYQL ++F Sbjct: 919 APPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFT 978 Query: 864 FDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTE 923 F G S K +++ P P A P + + P Sbjct: 979 FQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFA 1038 Query: 924 LASAPV---PSPAPPPEAPRGLGASPSSCGFQVARPRFSATRTGLQAHVWRP 972 AS+PV P P P +P+ S SS F RP+FSA ++G+ VW+P Sbjct: 1039 EASSPVSASPVPVGIPTSPK--QESASSSYFVAPRPKFSAKKSGVTIQVWKP 1088 Score = 84.3 bits (207), Expect = 5e-16 Identities = 36/86 (41%), Positives = 63/86 (73%) Query: 1 MGAEEEVLVTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVS 60 MG + + ++++GGAPWGFRL GG EQ++PLQV+KIR +S+A +GL E D++++ING Sbjct: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60 Query: 61 CTNLSHASAMSLIDASGNQLVLTVQR 86 C +L++ + L+++ + L + ++R Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKR 86 Score = 44.7 bits (104), Expect = 4e-04 Identities = 80/352 (22%), Positives = 124/352 (35%), Gaps = 51/352 (14%) Query: 181 PAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLP---------------HGPL 225 P P P + SQ + VS P W G A PPA P + P Sbjct: 758 PVAPKPAVKSSSSQPVTPVS-PVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPA 816 Query: 226 RPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLT 285 RP L + GP P A + YT K ++Q ++ + Sbjct: 817 RPASTL-NVAGPFKGPQAAVASQNYTPK-PTVSTPTVNAVQPGAVGPS-----------N 863 Query: 286 AAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARS 345 P +G +F KR+ R +KY + S A + PT + S+ R+ Sbjct: 864 ELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQS----PTPSLPASWKYSSNVRA 919 Query: 346 LTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQEL 405 + LA S+ S Q S +G + + + + + Q + ++S L Sbjct: 920 PPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNAS---L 976 Query: 406 ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPA----P 461 +P +G +S + SA LPP P+ A ASP Q PA P Sbjct: 977 FTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNA--ASPTNVQASSVYSVPAYTSPP 1034 Query: 462 SIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQ 513 S F ++ P + P + P +PK+ + S AP P S++ Sbjct: 1035 SFFAEASSPVSAS-----PVPVGI---PTSPKQESAS-SSYFVAPRPKFSAK 1077 >gi|193083191 synaptopodin 2 isoform c [Homo sapiens] Length = 1109 Score = 341 bits (875), Expect = 2e-93 Identities = 288/829 (34%), Positives = 386/829 (46%), Gaps = 189/829 (22%) Query: 244 EDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQ 303 +D + + +A+ A+L+R+ESL EK +KEAK+KC++IA LLT APNP+SKGVLMFKKRR+ Sbjct: 343 KDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRR 402 Query: 304 RAKKYTLVSFGAA--AGTGAEEEDGVPP---------TSESELDEEAFSDARSLTN--QS 350 RA+KYTLVS+G EEE+G SESE+DEE SD T Sbjct: 403 RARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNF 462 Query: 351 DWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQEL----- 405 DWDS +D+E + + G + L + +G+G +F ++R+R D T + Sbjct: 463 DWDSGLVDIE-----KKLNRGDKMEM---LPDTTGKGALMFAKRRERMDQITAQKEEDKV 514 Query: 406 ----ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPR-----PFQPGGGA 456 +R + AA +GL++ Q E+ S + + P Q G Sbjct: 515 GGTPSREQDAAQT--DGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSG 572 Query: 457 PTPAPSI-----FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 511 + +I NR+A+PF PG Q T P +P R S PAPPP+ S Sbjct: 573 TSETANIQRMVPMNRTAKPF-PGSVNQPAT-------PFSPTRNMTSPIADFPAPPPY-S 623 Query: 512 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 571 + P P +F+ GV S P++G P P P PAP Sbjct: 624 AVTPPP-DAFSRGVSS--PIAGPAQPP--------------PWPQ-----------PAPW 655 Query: 572 SAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRG 631 S A ++ E ++R++RISVPA RTGILQEA+RR Sbjct: 656 SQPAFYDSS------------------------ERIASRDERISVPAKRTGILQEAKRRS 691 Query: 632 TRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG-GAESGPEEDALSLGAEACNFMQPV 690 T K MF +E K SPNPELLSL+QN + K G G +SGPEED LSLGAEACNFMQ Sbjct: 692 TTKPMFT--FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSS 749 Query: 691 GARSYKTLPHVTPKTPPPMAPK------TPPPMTPKTP---PPVAPK------------- 728 A+ KTPPP+APK + P+TP +P P VAP Sbjct: 750 SAKQ---------KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKG 800 Query: 729 -------------PPSR--------GLLDGLVNGAASSAGIPEP---------------- 751 PP+R G G AS P+P Sbjct: 801 TVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVG 860 Query: 752 -----PRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIR 806 P + GRG +LFAKRQSR ++YVV+ R+ SPTPSLP SWKYS N+R Sbjct: 861 PSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ--AHAARAQSPTPSLPASWKYSSNVR 918 Query: 807 APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQG---IKALDFMRHQPYQLKTAMFC 863 APPP+AYNP+ SP +P AA + +Q + K+G + ALD M+HQPYQL ++F Sbjct: 919 APPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFT 978 Query: 864 FDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTE 923 F G S K +++ P P A P + + P Sbjct: 979 FQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFA 1038 Query: 924 LASAPV---PSPAPPPEAPRGLGASPSSCGFQVARPRFSATRTGLQAHV 969 AS+PV P P P +P+ S SS F RP+FSA ++G+ V Sbjct: 1039 EASSPVSASPVPVGIPTSPK--QESASSSYFVAPRPKFSAKKSGVTIQV 1085 Score = 84.3 bits (207), Expect = 5e-16 Identities = 36/86 (41%), Positives = 63/86 (73%) Query: 1 MGAEEEVLVTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVS 60 MG + + ++++GGAPWGFRL GG EQ++PLQV+KIR +S+A +GL E D++++ING Sbjct: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60 Query: 61 CTNLSHASAMSLIDASGNQLVLTVQR 86 C +L++ + L+++ + L + ++R Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKR 86 Score = 45.4 bits (106), Expect = 3e-04 Identities = 83/367 (22%), Positives = 128/367 (34%), Gaps = 51/367 (13%) Query: 181 PAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLP---------------HGPL 225 P P P + SQ + VS P W G A PPA P + P Sbjct: 758 PVAPKPAVKSSSSQPVTPVS-PVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPA 816 Query: 226 RPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLT 285 RP L + GP P A + YT K ++Q ++ + Sbjct: 817 RPASTL-NVAGPFKGPQAAVASQNYTPK-PTVSTPTVNAVQPGAVGPS-----------N 863 Query: 286 AAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARS 345 P +G +F KR+ R +KY + S A + PT + S+ R+ Sbjct: 864 ELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQS----PTPSLPASWKYSSNVRA 919 Query: 346 LTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQEL 405 + LA S+ S Q S +G + + + + + Q + ++S L Sbjct: 920 PPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNAS---L 976 Query: 406 ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPA----P 461 +P +G +S + SA LPP P+ A ASP Q PA P Sbjct: 977 FTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNA--ASPTNVQASSVYSVPAYTSPP 1034 Query: 462 SIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLG-GLSPAPPPFLSSQGPTPLPS 520 S F ++ P + P + P +PK+ + S ++P P G T Sbjct: 1035 SFFAEASSPVSAS-----PVPVGI---PTSPKQESASSSYFVAPRPKFSAKKSGVTIQVK 1086 Query: 521 FTSGVPS 527 SG+ S Sbjct: 1087 CKSGIHS 1093 >gi|193083183 synaptopodin 2 isoform a [Homo sapiens] Length = 1261 Score = 340 bits (873), Expect = 3e-93 Identities = 287/825 (34%), Positives = 385/825 (46%), Gaps = 189/825 (22%) Query: 244 EDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQ 303 +D + + +A+ A+L+R+ESL EK +KEAK+KC++IA LLT APNP+SKGVLMFKKRR+ Sbjct: 343 KDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRR 402 Query: 304 RAKKYTLVSFGAA--AGTGAEEEDGVPP---------TSESELDEEAFSDARSLTN--QS 350 RA+KYTLVS+G EEE+G SESE+DEE SD T Sbjct: 403 RARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNF 462 Query: 351 DWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQEL----- 405 DWDS +D+E + + G + L + +G+G +F ++R+R D T + Sbjct: 463 DWDSGLVDIE-----KKLNRGDKMEM---LPDTTGKGALMFAKRRERMDQITAQKEEDKV 514 Query: 406 ----ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPR-----PFQPGGGA 456 +R + AA +GL++ Q E+ S + + P Q G Sbjct: 515 GGTPSREQDAAQT--DGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSG 572 Query: 457 PTPAPSI-----FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 511 + +I NR+A+PF PG Q T P +P R S PAPPP+ S Sbjct: 573 TSETANIQRMVPMNRTAKPF-PGSVNQPAT-------PFSPTRNMTSPIADFPAPPPY-S 623 Query: 512 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 571 + P P +F+ GV S P++G P P P PAP Sbjct: 624 AVTPPP-DAFSRGVSS--PIAGPAQPP--------------PWPQ-----------PAPW 655 Query: 572 SAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRG 631 S A ++ E ++R++RISVPA RTGILQEA+RR Sbjct: 656 SQPAFYDSS------------------------ERIASRDERISVPAKRTGILQEAKRRS 691 Query: 632 TRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG-GAESGPEEDALSLGAEACNFMQPV 690 T K MF +E K SPNPELLSL+QN + K G G +SGPEED LSLGAEACNFMQ Sbjct: 692 TTKPMFT--FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSS 749 Query: 691 GARSYKTLPHVTPKTPPPMAPK------TPPPMTPKTP---PPVAPK------------- 728 A+ KTPPP+APK + P+TP +P P VAP Sbjct: 750 SAKQ---------KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKG 800 Query: 729 -------------PPSR--------GLLDGLVNGAASSAGIPEP---------------- 751 PP+R G G AS P+P Sbjct: 801 TVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVG 860 Query: 752 -----PRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIR 806 P + GRG +LFAKRQSR ++YVV+ R+ SPTPSLP SWKYS N+R Sbjct: 861 PSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ--AHAARAQSPTPSLPASWKYSSNVR 918 Query: 807 APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQG---IKALDFMRHQPYQLKTAMFC 863 APPP+AYNP+ SP +P AA + +Q + K+G + ALD M+HQPYQL ++F Sbjct: 919 APPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFT 978 Query: 864 FDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTE 923 F G S K +++ P P A P + + P Sbjct: 979 FQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFA 1038 Query: 924 LASAPV---PSPAPPPEAPRGLGASPSSCGFQVARPRFSATRTGL 965 AS+PV P P P +P+ S SS F RP+FSA ++G+ Sbjct: 1039 EASSPVSASPVPVGIPTSPK--QESASSSYFVAPRPKFSAKKSGV 1081 Score = 84.3 bits (207), Expect = 5e-16 Identities = 36/86 (41%), Positives = 63/86 (73%) Query: 1 MGAEEEVLVTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVS 60 MG + + ++++GGAPWGFRL GG EQ++PLQV+KIR +S+A +GL E D++++ING Sbjct: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60 Query: 61 CTNLSHASAMSLIDASGNQLVLTVQR 86 C +L++ + L+++ + L + ++R Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKR 86 Score = 47.8 bits (112), Expect = 5e-05 Identities = 121/552 (21%), Positives = 190/552 (34%), Gaps = 88/552 (15%) Query: 181 PAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLP---------------HGPL 225 P P P + SQ + VS P W G A PPA P + P Sbjct: 758 PVAPKPAVKSSSSQPVTPVS-PVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPA 816 Query: 226 RPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLT 285 RP L + GP P A + YT K ++Q ++ + Sbjct: 817 RPASTL-NVAGPFKGPQAAVASQNYTPK-PTVSTPTVNAVQPGAVGPS-----------N 863 Query: 286 AAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARS 345 P +G +F KR+ R +KY + S A + PT + S+ R+ Sbjct: 864 ELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQS----PTPSLPASWKYSSNVRA 919 Query: 346 LTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQEL 405 + LA S+ S Q S +G + + + + + Q + ++S L Sbjct: 920 PPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNAS---L 976 Query: 406 ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPA----P 461 +P +G +S + SA LPP P+ A ASP Q PA P Sbjct: 977 FTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNA--ASPTNVQASSVYSVPAYTSPP 1034 Query: 462 SIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSF 521 S F ++ P + P + P +PK+ + S SS P P F Sbjct: 1035 SFFAEASSPVSAS-----PVPVGI---PTSPKQESAS------------SSYFVAPRPKF 1074 Query: 522 T---SGVPSHAPVSGSPSTPRSSGPVTATSS-LYIPAPSRPVTPGG----APEPPAPPSA 573 + SGV RS P +TS +Y P S P A + P P A Sbjct: 1075 SAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEA 1134 Query: 574 AAMTSTASI---FLSAPLRPS--ARPEAPAPGPGAPEPPSAREQRIS-VPAARTGILQEA 627 AA + + F ++ S A + A P PP +R+S +P + Sbjct: 1135 AAKSPLGLVDDAFQPRNIQESIVANVVSAARRKVLPGPPEDWNERLSYIPQTQ------- 1187 Query: 628 RRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM 687 + M G++E + N + + Q + P A ++ + A+ ++ Sbjct: 1188 -----KAYMGSCGRQEYNVTANNNMSTTSQYGSQLPYAYYRQASRNDSAIMSMETRSDYC 1242 Query: 688 QPVGARSYKTLP 699 PV +Y P Sbjct: 1243 LPVADYNYNPHP 1254 >gi|158303333 synaptopodin isoform B [Homo sapiens] Length = 685 Score = 154 bits (390), Expect = 3e-37 Identities = 156/518 (30%), Positives = 216/518 (41%), Gaps = 76/518 (14%) Query: 461 PSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP-PPFLSSQGPTPLP 519 PS+ NR+ARPF G+Q P TS + R +P G +PAP PP L + P P Sbjct: 233 PSVVNRTARPF--GIQA--PGGTSQMER--SPMLERRHFGEKAPAPQPPSLPDRSPRPQR 286 Query: 520 SFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTST 579 S P +P S RP+ G PP + Sbjct: 287 HIMSRSPMVERRMMGQRSPASE--------------RRPL--GNFTAPPTYTETLSTAPL 330 Query: 580 ASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEA-RRRGTRKQMFR 638 AS S P P + +P S+ + +VPA++TGIL+E+ RRG+RK MF Sbjct: 331 ASWVRSPPSYSVLYPSS--------DPKSSHLKGQAVPASKTGILEESMARRGSRKSMF- 381 Query: 639 PGKEETKNSPNPELLSLVQNLDEKPR-AGGAESGPEEDALSLGAEACNFMQPVGARSYKT 697 E+ K +PNP+LL LVQ DEK R E G EE+ +LGAEA NF Q R + Sbjct: 382 TFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRD-RA 440 Query: 698 LPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGR 757 P + P A P P P P++ L + G+ Sbjct: 441 SPAAAEEVVPEWASCLKSPRIQAKPKP----KPNQNLSEA-----------------SGK 479 Query: 758 GGELFAKRQSRADRYVVEGTP-GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPL 816 G EL+A+RQSR ++YV+E + P L R PSPT SLP SWKY N +A Sbjct: 480 GAELYARRQSRMEKYVIESSSHTPELA---RCPSPTMSLPSSWKYPTNAPGAFRVASR-- 534 Query: 817 LSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEV--PPTPGPI 874 SP ART P + G P+ G+ + + PYQL+ ++F + P P Sbjct: 535 -SP-----ARTPPASLYHG--YLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPR 586 Query: 875 ASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP 934 A+ K + + + A P+ P+ +P T+ + + S P Sbjct: 587 AASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDIS 646 Query: 935 PPEAPRGLGASPSSCGFQVARPRFSATRTGLQAHVWRP 972 P R S Q RP FS G++A VW+P Sbjct: 647 PVSPSRAW----SPRAKQAPRPSFSTRNAGIEAQVWKP 680 Score = 41.2 bits (95), Expect = 0.005 Identities = 124/549 (22%), Positives = 185/549 (33%), Gaps = 81/549 (14%) Query: 68 SAMSLIDASGNQLVLTVQ-----RLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQP 122 S+ LID N LV++ R A P + S + P S ++ + P Sbjct: 189 SSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAP 248 Query: 123 LQPGSL-RSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSP 181 + RSP ++GE P+ ++ RP+R +R S Sbjct: 249 GGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASE 308 Query: 182 AEPAPTIPGPPSQGDSRVSSP--SWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVP 239 P PP+ ++ ++P SW ++ PP+ ++L P + HL Sbjct: 309 RRPLGNFTAPPTYTETLSTAPLASW-----VRSPPSYSVLYPSSDPKSS-HL-------- 354 Query: 240 HPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCR-TIASLLTAAPNPHSKGVLMF 298 K + + L+E + K T PNP ++ Sbjct: 355 -------------KGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQT 401 Query: 299 --KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAF-----SDARSLTNQSD 351 +KRRQR + G EEE S +E S A + + Sbjct: 402 ADEKRRQRDQ----------GEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPE 451 Query: 352 WDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQR-------ADSSTQE 404 W S L +A + Q LSE SG+G +L+ +++ R + S T E Sbjct: 452 WAS-CLKSPRIQAKPKPKPNQN------LSEASGKGAELYARRQSRMEKYVIESSSHTPE 504 Query: 405 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVAS-PRPFQPGGGAPTPAPSI 463 LAR M + P +AP V SP P AS + P G P P+ Sbjct: 505 LARCPSPTMSLPSSWKYP---TNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPT- 560 Query: 464 FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTS 523 + P L P P A A S L P P +G P PS Sbjct: 561 -KQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLP-----KGALP-PSPAL 613 Query: 524 GVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIF 583 PS + S + S TA S Y PV+P A P A + ST + Sbjct: 614 PRPSRSSPGLYTSPGQDSLQPTAVSPPY-GGDISPVSPSRAWSPRAKQAPRPSFSTRNAG 672 Query: 584 LSAPL-RPS 591 + A + +PS Sbjct: 673 IEAQVWKPS 681 >gi|40353727 synaptopodin isoform A [Homo sapiens] Length = 903 Score = 147 bits (370), Expect = 6e-35 Identities = 157/530 (29%), Positives = 216/530 (40%), Gaps = 86/530 (16%) Query: 461 PSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP-PPFLSSQGPTPLP 519 PS+ NR+ARPF G+Q P TS + R +P G +PAP PP L + P P Sbjct: 233 PSVVNRTARPF--GIQA--PGGTSQMER--SPMLERRHFGEKAPAPQPPSLPDRSPRPQR 286 Query: 520 SFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTST 579 S P +P S RP+ G PP + Sbjct: 287 HIMSRSPMVERRMMGQRSPASE--------------RRPL--GNFTAPPTYTETLSTAPL 330 Query: 580 ASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEA-RRRGTRKQMFR 638 AS S P P + +P S+ + +VPA++TGIL+E+ RRG+RK MF Sbjct: 331 ASWVRSPPSYSVLYPSS--------DPKSSHLKGQAVPASKTGILEESMARRGSRKSMF- 381 Query: 639 PGKEETKNSPNPELLSLVQNLDEKPR-AGGAESGPEEDALSLGAEACNFMQPVGARSYKT 697 E+ K +PNP+LL LVQ DEK R E G EE+ +LGAEA NF Q R + Sbjct: 382 TFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRD-RA 440 Query: 698 LPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGR 757 P + P A P P P P++ L + G+ Sbjct: 441 SPAAAEEVVPEWASCLKSPRIQAKPKP----KPNQNLSEA-----------------SGK 479 Query: 758 GGELFAKRQSRADRYVVEGTP-GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPL 816 G EL+A+RQSR ++YV+E + P L R PSPT SLP SWKY N +A Sbjct: 480 GAELYARRQSRMEKYVIESSSHTPELA---RCPSPTMSLPSSWKYPTNAPGAFRVASR-- 534 Query: 817 LSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEV--PPTPGPI 874 SP ART P + G P+ G+ + + PYQL+ ++F + P P Sbjct: 535 -SP-----ARTPPASLYHG--YLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPR 586 Query: 875 ASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP 934 A+ K + + + A P+ P+ +P T+ + + S P Sbjct: 587 AASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDIS 646 Query: 935 PPEAPRGLGASPSSCGFQVARPRFSATRTGLQAH----------VWRPGA 974 P R S Q RP FS G++A W PGA Sbjct: 647 PVSPSRAW----SPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGA 692 Score = 73.9 bits (180), Expect = 7e-13 Identities = 178/777 (22%), Positives = 256/777 (32%), Gaps = 142/777 (18%) Query: 68 SAMSLIDASGNQLVLTVQ-----RLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQP 122 S+ LID N LV++ R A P + S + P S ++ + P Sbjct: 189 SSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAP 248 Query: 123 LQPGSL-RSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSP 181 + RSP ++GE P+ ++ RP+R +R S Sbjct: 249 GGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASE 308 Query: 182 AEPAPTIPGPPSQGDSRVSSP--SWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVP 239 P PP+ ++ ++P SW ++ PP+ ++L P + HL Sbjct: 309 RRPLGNFTAPPTYTETLSTAPLASW-----VRSPPSYSVLYPSSDPKSS-HL-------- 354 Query: 240 HPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCR-TIASLLTAAPNPHSKGVLMF 298 K + + L+E + K T PNP ++ Sbjct: 355 -------------KGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQT 401 Query: 299 --KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAF-----SDARSLTNQSD 351 +KRRQR + G EEE S +E S A + + Sbjct: 402 ADEKRRQRDQ----------GEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPE 451 Query: 352 WDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRAD-------SSTQE 404 W S L +A + Q LSE SG+G +L+ +++ R + S T E Sbjct: 452 WAS-CLKSPRIQAKPKPKPNQN------LSEASGKGAELYARRQSRMEKYVIESSSHTPE 504 Query: 405 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASP-RPFQPGGGAPTPAPSI 463 LAR M + P +AP V SP P AS + P G P P+ Sbjct: 505 LARCPSPTMSLPSSWKYPT---NAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPT- 560 Query: 464 FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTS 523 + P L P P A A S L P P +G P PS Sbjct: 561 -KQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLP-----KGALP-PSPAL 613 Query: 524 GVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIF 583 PS + S + S TA S Y PV+P A P A + ST + Sbjct: 614 PRPSRSSPGLYTSPGQDSLQPTAVSPPY-GGDISPVSPSRAWSPRAKQAPRPSFSTRNAG 672 Query: 584 LSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEE 643 + A R + P +P PGA PPS+ + +S + PG+ Sbjct: 673 IEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGP------------------WEPGRGS 714 Query: 644 TKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEA---CNFMQPVGARSYKTLPH 700 + +SP P L P + S L EA +Q + AR+ Sbjct: 715 SMSSPPP--------LPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAAR 766 Query: 701 VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGE 760 +P + P P +P PP P PP P PPR+ Sbjct: 767 RKSASPRSAGAENPRPFSPPRAPPPPPPPP------------------PPPPRM------ 802 Query: 761 LFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLL 817 R + R PG P PRSP P PS SP R+P P P L Sbjct: 803 ----RSPQPARPGSAAVPGAAFAPIPRSPLPA---GPSSCTSP--RSPLPAPPRPFL 850 Score = 45.4 bits (106), Expect = 3e-04 Identities = 138/623 (22%), Positives = 207/623 (33%), Gaps = 159/623 (25%) Query: 442 APVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG 501 +P+ R F AP P PS+ +RS RP + + P + +P LG Sbjct: 257 SPMLERRHFGEKAPAPQP-PSLPDRSPRP-QRHIMSRSPMVERRMMGQRSPASERRPLGN 314 Query: 502 LSPAPPPFLSSQGPTPLPSFTSGVPSHAPV--SGSPSTPRSSG---PVTATS-------- 548 + APP + + PL S+ PS++ + S P + G P + T Sbjct: 315 FT-APPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMAR 373 Query: 549 -----SLYIPAPSRPVTPG----------------------GAPEPPAPPSAAAMTSTAS 581 S++ VTP G E P A+ + AS Sbjct: 374 RGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPF-----ALGAEAS 428 Query: 582 IFLSAPLRPSARPEAPAPGPGAPE-------------PPSAREQRISVPAARTGILQEAR 628 F P P R A PE P Q +S + + L R Sbjct: 429 NFQQEPA-PRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARR 487 Query: 629 RRGTRKQMFRPGKE--ETKNSPNPELLSLVQNLDEKPRAGGA-ESGPEEDALSLGAEACN 685 + K + E P+P + SL + A GA A + A + Sbjct: 488 QSRMEKYVIESSSHTPELARCPSPTM-SLPSSWKYPTNAPGAFRVASRSPARTPPASLYH 546 Query: 686 FMQPVGARSYKTLPHVTPKTPPPMAP--------KTPPPMTPKTPPPVAPKPPSRGLLDG 737 P P T + P + P K P ++P+ P KP S L+ Sbjct: 547 GYLPENG---VLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPA--KPSSLDLVPN 601 Query: 738 LVNGAAS-SAGIPEPPR-------------LQGR------GGELFAKRQSRADRYVVEGT 777 L GA S +P P R LQ GG++ SRA + Sbjct: 602 LPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQA 661 Query: 778 PGPGLGPR-------------PRSPSPTP--SLPPS----------WK--YSPNIRAPPP 810 P P R P SP TP S PPS W+ ++ +PPP Sbjct: 662 PRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPP 721 Query: 811 IAYNPLLSPFFPQAARTLPKAQSQG-PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 869 + P +SP + + + + + +++ P + Q + A + + + Sbjct: 722 LPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRK------------- 768 Query: 870 TPGPIASGSPKTARVQEIRRFS---TPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELAS 926 S SP++A + R FS P P P P P + +P+ A R A+ Sbjct: 769 ------SASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA--------RPGSAA 814 Query: 927 APVPSPAPPPEAPRGLGASPSSC 949 P + AP P +P L A PSSC Sbjct: 815 VPGAAFAPIPRSP--LPAGPSSC 835 Score = 37.0 bits (84), Expect = 0.090 Identities = 35/115 (30%), Positives = 44/115 (38%), Gaps = 13/115 (11%) Query: 94 QSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEK 153 +S SP +P P P P P P P +RSP + + G A Sbjct: 768 KSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPAR----PGSAAVPGAAFAPI 823 Query: 154 PRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGA 208 PR P GP+ T P +P PA P P + S DS VS S + GA Sbjct: 824 PRSPLPAGPSSCTSPRSP--------LPAPPRPFL-YRRSPTDSDVSLDSEDSGA 869 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 115 bits (287), Expect = 3e-25 Identities = 240/994 (24%), Positives = 329/994 (33%), Gaps = 183/994 (18%) Query: 106 PLSPLSPEPPGA-----------PVPQPLQ--PGSLRSPPDSEAYYGETDSDADG--PAT 150 P+SP P+P P + LQ P SL P S A G T P Sbjct: 504 PVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLV 563 Query: 151 QEKPRRPRRRGPTRPTPP-GAPPDEVYLSDSPAEPAPTIPGPPSQGDSRV---SSPSWED 206 Q P+ T +P P+ S EP P I P S S + SS S Sbjct: 564 QAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLP-IGKPASSMTSPLGVNSSASVIK 622 Query: 207 GAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDL---TTTYTQKAKQAKLQRAE 263 + P + LL + P P+ P VA T+TYT A L+ Sbjct: 623 TDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF-LEGTV 681 Query: 264 SLQEKSIKEAKTKCRTIASLLTA------APNPHSK-----GVLMFKKRRQRAKKYTLVS 312 SL K+ + T+ + TA AP+P + +++ + + +L Sbjct: 682 SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP 741 Query: 313 FGAAAGT----GAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAG--- 365 G GT G + P + S + S T S YL + G Sbjct: 742 AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSV 801 Query: 366 ---------SRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNG 416 + S G + +G S VS + S A + Sbjct: 802 SPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSP 861 Query: 417 EGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQ---PGGGAPTPAPSIFNRSARP--- 470 +G +P P+ LPP P P PF P AP AP++ S+ P Sbjct: 862 KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA 921 Query: 471 -FTPGLQGQRPTTTSVIFRPLAPKRANDSLGG--LSPAP-----PPFLSSQGP-----TP 517 TP +G P + S P P S G +P+P PP + P TP Sbjct: 922 RATPAPKGI-PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP 980 Query: 518 LPSFTSGVPSHAPVS--GSPSTPRSSG---PVTATSSLYIPAPSRPVTPGGAPEPPA--P 570 P P+ P S G P+TP G P T +P+ P GA PPA P Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040 Query: 571 PSAAAMTSTASIFLSAPLRPSARPEAPAPGP------GAPEPPSAREQR----------- 613 PS + + AP P+A +P GP GAP PP+A Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100 Query: 614 ------ISVPAARTGILQEARRRG--TRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRA 665 + P + G L +G T P + +P P+ Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160 Query: 666 GGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTP--PPMAPK----TPPPMTP 719 GG + P + A + A P G + + P P TP P +PK TP P Sbjct: 1161 GGLATPPPKGAPT--TPAATPPSPKGGLATPS-PKGAPTTPAATPPSPKGGLATPSPKGA 1217 Query: 720 KTPPPVAPKPPSRGLLDGLVNGAASS-----------------AGIPEPPRLQG---RGG 759 T P P P GL GA ++ G P PP +GG Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277 Query: 760 ELFAKRQSRADRYVVEGTP-----GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYN 814 + + VV TP GP P +P+P + PPS K SP P Sbjct: 1278 LATPPHKGAPNPAVV--TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335 Query: 815 PLLSPFFPQAARTLPKA--QSQGPRATP--KQGIKALDFMRHQPYQLKTAMFCFDEVPPT 870 P ++P P+ TLP S+G TP K+G PP Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG----------------------PTPPA 1373 Query: 871 PGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTV--LAPRAATTLDEPIWRTELA--- 925 P G P A + P P +P +P V L+P+ A P+ R A Sbjct: 1374 ATPSHKGGP--AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA--TPVTREGAATPS 1429 Query: 926 ----SAPVPSP-----APPPEAPRGLGASPSSCG 950 + P +P AP AP+G A+PSS G Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463 Score = 109 bits (273), Expect = 1e-23 Identities = 218/916 (23%), Positives = 303/916 (33%), Gaps = 103/916 (11%) Query: 90 EGPVQSPSPHELQVLSPLS---------------PLSPEPPGAPVPQPLQPGSLRSPPDS 134 EGP +P+P + LS S P SP P GAP P P S + P + Sbjct: 898 EGPA-TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956 Query: 135 EA-YYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEP----APTIP 189 + + T A P+ + P P +G PTPP A P PA P APT P Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATPSPKGA--PTPPAATPPSP--KGGPATPSPKGAPTPP 1012 Query: 190 G--PPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLT 247 PPS S ++P + GA+ PPA P G P P+ P A L Sbjct: 1013 AVTPPSPKGSPAATP-FPKGAST--PPAATPPSPKG----SPAATPLPKGAPTTPAATLP 1065 Query: 248 TTY----TQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQ 303 + T K A A + A T A + AA P KG L + Sbjct: 1066 SPKGGPATPSLKGAPTPPAATPPSPKGGPA-TPSPKGAPMPPAATPPSPKGGLATPPHKG 1124 Query: 304 RAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELAR 363 G G P T + A + +P + Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP-TTPAATPPSPK 1183 Query: 364 AGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPP 423 G +G+ + S +G A S + A + +G + P Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKG--------GLATPSPKGAPTTPAATPPSPKGGLATP 1235 Query: 424 RAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARP----------FTP 473 + AP A PPSP P P P A TP PS+ A P TP Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP-PSLKGGLATPPHKGAPNPAVVTP 1294 Query: 474 GLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPT---PLPSFTSGVPSHAP 530 P T+ P P S G PPP + P P P T +P+ P Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354 Query: 531 VS-GSPSTPRSSG---PVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSA 586 S G P+TP S P AT S P +P P P+P TS A I Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP--TSPAVI---- 1408 Query: 587 PLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKN 646 PL P P P GA P ++ PA L++A K P +K Sbjct: 1409 PLSPKKAPATPVTREGAATPSKG---DLTPPAVTPVSLKKAPATSAPKG--GPATPSSKG 1463 Query: 647 SPN-PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKT 705 P P + P+ S P++ + + V S K +P Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523 Query: 706 PPPMAPKTPPPMTPKTPPPVAPK----PPSRGLLDGLVNGAASSAGIPEPPRLQGRGGEL 761 P+AP T ++ KTP +APK PP+ V + IP P Sbjct: 1524 RDPIAP-TATLLSKKTPATLAPKEALIPPAM-----TVPSPKKTPAIPTPKEAPATPSSK 1577 Query: 762 FAKRQSRADRYVVEGTPGPG--------LGPRPR-SPSPTPSLPPSWKYSPNIRAPPPIA 812 A +G P P P P+ +P+P PPS + P AP Sbjct: 1578 EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637 Query: 813 YNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPG 872 +P ++P + + T P + + AT Q K L + P LK + V P P Sbjct: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLP-AKKGPTALKEVL-----VAPAPE 1691 Query: 873 PIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSP 932 + T + + ++ S +P +P A +T P+ + S+ Sbjct: 1692 STPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKG 1751 Query: 933 APPPEAPRGLGASPSS 948 +P+G A P S Sbjct: 1752 KDASHSPKGPLAPPES 1767 Score = 100 bits (248), Expect = 9e-21 Identities = 216/896 (24%), Positives = 291/896 (32%), Gaps = 144/896 (16%) Query: 96 PSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPR 155 PSP S ++PLSP+ P + P + P E T + PA Sbjct: 859 PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG--PATPAPKQAPALSMTSS 916 Query: 156 RPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPA 215 P++ T P P G P +P PA T P P +G SP W A PP A Sbjct: 917 SPKKARAT-PAPKGIPASP-SPKGAPTPPAATPPSP--KGGPATPSPKW----APTPPAA 968 Query: 216 EALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKT 275 GP P P P P + T + K A A + A T Sbjct: 969 TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG--APTPPAVTPPSPKGSPAAT 1026 Query: 276 KCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESEL 335 AS AA P K G+ A T + G P T + L Sbjct: 1027 PFPKGASTPPAATPPSPK--------------------GSPAATPLPK--GAPTTPAATL 1064 Query: 336 DEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQR 395 A + P + G +G+ + + S +G L Sbjct: 1065 PSPKGGPATPSLKGAP-TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG-GLATPPH 1122 Query: 396 QRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSP-----LPAPVASP--- 447 + A ++ P + G P A + P A PPSP P P +P Sbjct: 1123 KGAPTT----PAATPPSPKGGLATPPPKGAPTTP---AATPPSPKGGLATPPPKGAPTTP 1175 Query: 448 --RPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 505 P P GG TP+P P TP P+ + P +PK A + P+ Sbjct: 1176 AATPPSPKGGLATPSP-----KGAPTTPA--ATPPSPKGGLATP-SPKGAPTTPAATPPS 1227 Query: 506 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 565 P L++ P P+ + P G P+TP G T PA + P GG Sbjct: 1228 PKGGLATPSPKGAPTTPAATPPSP--KGGPATPPPKGAPTP------PAATPPSLKGGLA 1279 Query: 566 EPP--APPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGI 623 PP P+ A +T P P P A +P GAP PP+A P + G Sbjct: 1280 TPPHKGAPNPAVVT---------PPSPKGGP-ATSPPKGAPTPPAA------TPPSPKG- 1322 Query: 624 LQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEA 683 PG K +P P ++ P G + P S G Sbjct: 1323 --------------SPGTPPPKGAPTPPAVT-------PPSPKGTPTLPATTPSSKGGPT 1361 Query: 684 CNFMQ-----PVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGL 738 + P S+K P +TP + P P P P T P V P P + + Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPS-PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV 1420 Query: 739 V-NGAAS-SAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPS---PTP 793 GAA+ S G PP + + +++ A G P P P+ P+P Sbjct: 1421 TREGAATPSKGDLTPPAVTP-----VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSP 1475 Query: 794 SLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQ 853 PP+ K +P P P A TLP P+ P A R Sbjct: 1476 KEPPAPKQVATSSSPKKAPATPA-----PMGAPTLPAVIPSSPKEVP-----ATPSSRRD 1525 Query: 854 PYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPA-PQPTAEPLAPT---VLAP 909 P TA + P T P + P V ++ TPA P P P P+ +P Sbjct: 1526 PI-APTATLLSKKTPATLAPKEALIPPAMTVPSPKK--TPAIPTPKEAPATPSSKEASSP 1582 Query: 910 RAAT--TLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRFSATRT 963 A T T EL P + P EAP +P S A P T T Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPT 1638 Score = 80.1 bits (196), Expect = 9e-15 Identities = 217/921 (23%), Positives = 300/921 (32%), Gaps = 171/921 (18%) Query: 92 PVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQ 151 P +P P +P + P P G+P PL G+ +P + S GPAT Sbjct: 1023 PAATPFPKGAS--TPPAATPPSPKGSPAATPLPKGAPTTPAAT------LPSPKGGPATP 1074 Query: 152 EKPRRPR---------RRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQG--DSRVS 200 P + GP P+P GAP + +P P + PP +G + + Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPP---AATPPSPKGGLATPPHKGAPTTPAA 1131 Query: 201 SPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQ 260 +P G PPP A P P P G + P + TT K Sbjct: 1132 TPPSPKGGLATPPPKGAPTTP-AATPPSPK-----GGLATPPPKGAPTTPAATPPSPK-- 1183 Query: 261 RAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTG 320 L S K A T AA P KG L + G Sbjct: 1184 --GGLATPSPKGAPTT--------PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233 Query: 321 AEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQL 380 G P T + A + P + G +G+ + Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAP-TPPAATPPSLKGGLATPPHKGAPNPAVV 1292 Query: 381 SEVSGRGVQLFEQQRQRADSSTQELARVEPAAML-NGEGLQSPPRAQSAPPEAAVLPPSP 439 + S +G +S + A PAA + +G P + AP AV PPSP Sbjct: 1293 TPPSPKGGPA---------TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343 Query: 440 LPAPVASPRPFQPGGGAPTPA-----------------PSIFNRSAR--PFTPGLQGQRP 480 P GG TP+ P++ S + P P +G P Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD-P 1402 Query: 481 TTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPL-PSFTSGVPSHAPVSGSPSTPR 539 T+ +VI PL+PK+A + A P P + P P+ + G P+TP Sbjct: 1403 TSPAVI--PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPS 1460 Query: 540 SSGPVT------------------ATSSLYIPAPSRPVTPGGAPEPPAP-PSAAAMTSTA 580 S G T ATSS AP+ P P GAP PA PS+ Sbjct: 1461 SKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP-APMGAPTLPAVIPSSPK----- 1514 Query: 581 SIFLSAPLRPSARPEAPAPGP---GAPEPPSAREQRISVPAARTGILQEARRRGTRKQMF 637 P PS+R + AP P + + +P A T + + Sbjct: 1515 ----EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT-VPSPKKTPAIPTPKE 1569 Query: 638 RPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKT 697 P +K + +P ++ P P+E L A P + T Sbjct: 1570 APATPSSKEASSPPAVT--------PSTYKGAPSPKE---LLIPPAVTSPSP---KEAPT 1615 Query: 698 LPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSA--GIPEPPRLQ 755 P VTP + P P TP P T PPV P L D + A+ + G P + Sbjct: 1616 PPAVTPPS-PEKGPATPAPKGTPTSPPVTPS----SLKDSPTSPASVTCKMGATVPQASK 1670 Query: 756 GRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNP 815 G L AK+ A + V+ P P +PT P + K S PPI +P Sbjct: 1671 G----LPAKKGPTALKEVL---VAPAPESTPIITAPTRKGPQTKKSS---ATSPPICPDP 1720 Query: 816 LLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIA 875 K S+GP +T + + Q KTA G A Sbjct: 1721 ------------SAKNGSKGPLST----VAPAPLLPVQKDSSKTA----------KGKDA 1754 Query: 876 SGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPP 935 S SPK + STP E + P P +A+ P L AP P P P Sbjct: 1755 SHSPKGPLAPPESKASTPLTAAAFEKVLP---KPESASVSAAPSPPVSLPLAPSPVPTLP 1811 Query: 936 PEAPRGLGASPSSCGFQVARP 956 P+ PSS G + P Sbjct: 1812 PKQQ----FLPSSPGLVLESP 1828 Score = 67.8 bits (164), Expect = 5e-11 Identities = 120/493 (24%), Positives = 189/493 (38%), Gaps = 90/493 (18%) Query: 83 TVQRLADEGPVQSPSPHELQVLSP--LSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGE 140 T+ + P + P+P ++ S +P +P P GAP + P S + P + Sbjct: 1466 TLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPAT------ 1519 Query: 141 TDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAP----TIPGP---PS 193 P+++ P P ++ TP P E + + P+P IP P P+ Sbjct: 1520 -------PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572 Query: 194 QGDSRVSS------PSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLT 247 S+ +S PS GA P P E LL+P P P P V P E Sbjct: 1573 TPSSKEASSPPAVTPSTYKGA---PSPKE-LLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628 Query: 248 TTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKK 307 T K + + S+K++ T ++ + A SKG+ AKK Sbjct: 1629 ATPAPKGTPT----SPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL--------PAKK 1676 Query: 308 YTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDME-LARAGS 366 G A +E V P ES A + T +S SP + + A+ GS Sbjct: 1677 ----------GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGS 1726 Query: 367 RASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQ 426 + G LS V+ L Q+ + ++ + A P +G +PP ++ Sbjct: 1727 K----------GPLSTVA--PAPLLPVQKDSSKTAKGKDASHSP------KGPLAPPESK 1768 Query: 427 SAPPEAAVLPPSPLPAP-----VASPRPFQPGGGAPTPAPSI-FNRSARPFTPGLQGQRP 480 ++ P A LP P A+P P AP+P P++ + P +PGL + P Sbjct: 1769 ASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESP 1828 Query: 481 TTTSVIFRPLAPKRANDSLGGLSPAP----PPFLSSQGPTPLPSFTSGVPSHAPVSGSPS 536 + +PLAP ++ L + P P PF S P P ++G+P P + P Sbjct: 1829 S------KPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPK-SAGIPVPTPSAKQPV 1881 Query: 537 TPRSSGPVTATSS 549 T + G T + S Sbjct: 1882 TKNNKGSGTESDS 1894 Score = 64.3 bits (155), Expect = 5e-10 Identities = 164/695 (23%), Positives = 229/695 (32%), Gaps = 163/695 (23%) Query: 88 ADEGPVQSPSPHELQVLSPL-SPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDAD 146 A P +P+P SP SP +P P GAP P + P S + P A + Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361 Query: 147 GPATQEKPRRPR----------------RRGPTRPTPPGAPPDEVYLSDSPAEPAPTIP- 189 P+++E P P +RGP P+P G P + SP + AP P Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP-KKAPATPV 1420 Query: 190 -----GPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAE 244 PS+GD L PP + L P P P Sbjct: 1421 TREGAATPSKGD-------------LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467 Query: 245 DLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAA--PNPHSKGVLMFKKRR 302 T + K A Q A S K K T A L A +P +R Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPK--KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525 Query: 303 QRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELA 362 A TL+S A T A +E +PP ++T S +P + Sbjct: 1526 PIAPTATLLSKKTPA-TLAPKEALIPP---------------AMTVPSPKKTPAIPTPKE 1569 Query: 363 RAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSP 422 + +S+ S S G S +EL + PA + Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGA-------------PSPKELL-IPPAV--------TS 1607 Query: 423 PRAQSAPPEAAVLPPSP-----LPAPVASPR--PFQPGG--------------------- 454 P + AP AV PPSP PAP +P P P Sbjct: 1608 PSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667 Query: 455 ---GAP-------------TPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDS 498 G P PAP P G Q ++ + TS P P N S Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICP-DPSAKNGS 1726 Query: 499 LGGLSP-APPPFLSSQGPTPLPSFTSGVPSHAPVSG-SPSTPRSSGPVTAT--------- 547 G LS AP P L Q + + SH+P +P ++S P+TA Sbjct: 1727 KGPLSTVAPAPLLPVQKDSSKTAKGKDA-SHSPKGPLAPPESKASTPLTAAAFEKVLPKP 1785 Query: 548 -SSLYIPAPSRPVTPGGAPE--PPAPPSAAAMTSTASIFLSAPLRPSARPE--------A 596 S+ APS PV+ AP P PP + S+ + L +P +P A + Sbjct: 1786 ESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIP 1845 Query: 597 PAPGPGA----------PEPPSAREQRISVPAARTGILQEARRRGTRKQMFR--PGKEE- 643 P P G P P SA + P+A+ + + + GT P EE Sbjct: 1846 PEPISGGVPFQSVLVNMPTPKSAGIP-VPTPSAKQPVTKNNKGSGTESDSDESVPELEEQ 1904 Query: 644 --TKNSPNPELLSLVQNLDEKPRAGGAESGPEEDA 676 T+ + L+ +DE+P + +S E+ A Sbjct: 1905 DSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKA 1939 Score = 48.5 bits (114), Expect = 3e-05 Identities = 60/216 (27%), Positives = 79/216 (36%), Gaps = 36/216 (16%) Query: 416 GEGLQSPPRAQSAPP----EAAVLPPSP---LPAPVASPRPFQPGGGAPTP--APSIFNR 466 GE ++ P + P E AVLP S + A + P P P +P P P Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62 Query: 467 SARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLG-----GLSPAPPPFLSSQGPTPLPSF 521 A PF P+ +++ PL S G G +P P FL + P+ Sbjct: 63 QASPF--------PSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPA 114 Query: 522 TSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEP--PAPPSAAAMTST 579 + S TP SS P+ +L AP P +PPS A S Sbjct: 115 ALALASPMIAPTLKGTPSSSAPL----ALVALAPHSVQKSSAFPPNLLTSPPSVAVAESG 170 Query: 580 ASIFLSAPLRPSAR-------PEAPAPGP-GAPEPP 607 + I LSAP+ PS P P P G P PP Sbjct: 171 SVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPP 206 Score = 43.5 bits (101), Expect = 0.001 Identities = 44/160 (27%), Positives = 56/160 (35%), Gaps = 11/160 (6%) Query: 88 ADEGPVQSPSPHELQVLSPLS-PLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDAD 146 A P +P+P SP P +P P AP P P S + P + + G A Sbjct: 932 ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA- 990 Query: 147 GPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWED 206 AT P+ GP P+P GAP SP P P ++P Sbjct: 991 --ATPPSPKG----GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK 1044 Query: 207 GA-ALQPPPAEALLLPHG--PLRPGPHLIPMVGPVPHPVA 243 G+ A P P A P P G P + P P A Sbjct: 1045 GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084 Score = 38.5 bits (88), Expect = 0.031 Identities = 123/559 (22%), Positives = 184/559 (32%), Gaps = 88/559 (15%) Query: 405 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIF 464 L +V + N +G SPP S P V P + + + VAS P P+ Sbjct: 188 LNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVAS---------LPQTTPTTT 238 Query: 465 NRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSG 524 A P Q + T +SV+ P P SL P PP S LP TS Sbjct: 239 LAIASP-----QVKDTTISSVLISPQNP----GSLSLKGPVSPPAALSLSTQSLPVVTSS 289 Query: 525 VPSHAPVSGSPSTPRSSGPVTA---TSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTAS 581 + P + P P S G A SS P +P + +ST + Sbjct: 290 QKTAGP-NTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGA 348 Query: 582 IFLS----APLRPSARPEAPAP-------GPGAPEPPSAREQRISVPAARTGILQEARRR 630 + S P PS PA P + PS P+ + Sbjct: 349 SYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLS 408 Query: 631 GTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPV 690 T + + T + P LV + S+G P Sbjct: 409 PTTSLILKSSPNATYHYP------LVAQM---------------PVSSVGTTPLVVTNPC 447 Query: 691 G-ARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP-----PPVAPKPPSRGLLDGLVNGAAS 744 A + T V PPM+ + P +P PVAPK PS + L Sbjct: 448 TIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTL--RIPV 505 Query: 745 SAGIPEPPRLQGRGGELFAKRQSRADRYVV----EGTP----GPGLGPRPRSPSPTPSLP 796 S +P+P L+ + K ++ D V EG P GL + + P+ P + Sbjct: 506 SPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTK-KDPTVLPLVQ 564 Query: 797 PSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQ 856 + K SP+ ++ + +P + P P+A P P + + + Sbjct: 565 AAPKNSPSFQS---TSSSPEI-PLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASV 620 Query: 857 LKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEP--LAPTVLAPRAA-T 913 +KT + P + GP+ S T V P +A+P +APT + T Sbjct: 621 IKTDSYA---GPDSAGPLLKSSLITPTVAAF-------PLESADPAGVAPTTAKGTSTYT 670 Query: 914 TLDEPIWRTELASAPVPSP 932 T P ++ AP P Sbjct: 671 TTASPFLEGTVSLAPKNHP 689 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 102 bits (254), Expect = 2e-21 Identities = 235/963 (24%), Positives = 328/963 (34%), Gaps = 189/963 (19%) Query: 110 LSPEPPGAP-VPQPLQPGSLR-----------------------SPPDSEAYYGETDSDA 145 L+P PPG+P P P+ P +LR + P+S G T S Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA- 83 Query: 146 DGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSW- 204 G +++ RP G PP +S T PGP Q R+S+ Sbjct: 84 -GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 142 Query: 205 EDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAES 264 G A + P AL GP T T A+ RA Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGP------------------TPGTPSPAMARRSRAAG 184 Query: 265 LQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEE 324 + + A + A P P ++G +K A +++ AA Sbjct: 185 TEVGLPRPAPS----------ARPRPPTEGP---RKSVSSASEHSTTEPSPAARRRPSAG 231 Query: 325 DGVPPTSESELDEEAF---SDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLS 381 G+ + L A S ARS S +P RA + S+ + GL Sbjct: 232 GGLQRPASRSLSSSATPLSSPARS--GPSARGTP-------RAPAHPSQPKPKGLQAL-- 280 Query: 382 EVSGRGVQLFEQQRQRADS----STQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPP 437 R Q+ ++ A + S+ LA P+ + PP +A P A LPP Sbjct: 281 ----RPPQVTPPRKDAAPALGPLSSSPLATPSPSGT---KARPVPPPDNAATPLPATLPP 333 Query: 438 SPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRP-----LAP 492 SP P+A+P P P +P+ PS+ + P TP Q TT + P + P Sbjct: 334 SP---PLATPLPLAPP--SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388 Query: 493 KRANDSLGGLS----PAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSP------------- 535 + SL S P+P S Q T L S T +H+ ++ SP Sbjct: 389 IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA-THSFLTMSPRQTQASLTSPSRP 447 Query: 536 -STPRSSGPVTATSSLYIPAP-----SRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLR 589 STP S P+ A SL P S V+P +P P A++S AS APL Sbjct: 448 ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP--LQALSSLASHSPQAPLS 505 Query: 590 ----PSARPEAPAPGPGAPEPPSA--REQRISVPAARTGILQEARRRGTRKQMFRP---- 639 P ++ P PP++ ++P+ LQ A T + P Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565 Query: 640 -----GKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARS 694 +P PE S + P+A A + P L + P A Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIAT--PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623 Query: 695 YKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRL 754 LP P PP P +PP TP P AP + LL A + P PP + Sbjct: 624 XLALP---PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ------APFSPPPSPP-V 673 Query: 755 QGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYN 814 Q + S + + P P PSP S P S +P +APPP+A Sbjct: 674 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733 Query: 815 PLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPI 874 PL P P A+ + + + PR P L P L + PP P Sbjct: 734 PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA---KPPPQAPP 790 Query: 875 ASGSPKTARVQE------------------IRRFSTPAPQ------------PTAEPLAP 904 A +P + + +TP PQ P + P +P Sbjct: 791 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850 Query: 905 TVLAPRAATT--LDEPIWRTELASAPVPSPAPPPEAPRGLGASPSS--CGFQVARPRFSA 960 T+ APR T D + L A P P PPP SPSS G +A SA Sbjct: 851 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP------SRSPSSTLSGPDLAGHSSSA 904 Query: 961 TRT 963 T T Sbjct: 905 TST 907 Score = 94.0 bits (232), Expect = 6e-19 Identities = 211/834 (25%), Positives = 278/834 (33%), Gaps = 119/834 (14%) Query: 90 EGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDA---D 146 EGP +S S S + EP A +P G L+ P T + Sbjct: 203 EGPRKSVS-------SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255 Query: 147 GPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWED 206 GP+ + PR P P++P P G P + A GP S SPS Sbjct: 256 GPSARGTPRAPAH--PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313 Query: 207 GAALQPPPAEALLLPHGPLRPGPHL-IPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESL 265 + PP A LP L P P L P+ P P A T Q S+ Sbjct: 314 ARPVPPPDNAATPLP-ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSM 372 Query: 266 QEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEED 325 + +A +TI + PHS L + L S A G+ Sbjct: 373 TTPPM-QAPPSLQTIPPIQV----PHS---LTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424 Query: 326 GVPP-TSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGS----RASEGQGSGLGGQL 380 + S +A + S + DSP L L+ S + S L L Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPL 484 Query: 381 SEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPP--EAAVLPPS 438 + + + +A S+ + +E + L LQ+PP + + PP L P Sbjct: 485 TIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPP 544 Query: 439 PL---PAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRP---LAP 492 PL AP+ +P P P PAP P T P T S I P P Sbjct: 545 PLQTASAPLTTPHLETP----PCPAPCPLQAPPSPLTT----PPPETPSSIATPPPQAPP 596 Query: 493 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVS-------------------- 532 A+ L GL P+PP + P P + P AP S Sbjct: 597 ALASPPLQGL-PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655 Query: 533 ------GSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAA--MTSTASIFL 584 +P +P S PV A S P S PV+P P APPS AA + S Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFS---PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 712 Query: 585 SAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEET 644 S P+ PSA P AP P A P P A + A + + Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPLQVPPS----PPASPPMSPSATPPPRVPPLLAAPPLQV 768 Query: 645 KNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPK 704 SP P L + P+A A + P AL + +F +LP Sbjct: 769 PPSP-PASLPMSPLAKPPPQAPPALATPPLQALP--SPPASFPGQAPFSPSASLPMSPLA 825 Query: 705 TPPPMAPKT-------PPPMTPKTPPPVAPKPPSRGLLDGLVNG----AASSAGIPEPPR 753 TPPP AP PP P +P AP+ P D V+G A + G P PP Sbjct: 826 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885 Query: 754 LQGR---GGELFAKRQSRADRYVVE--GTPGPGLGPRPRSPSPTPSL----PPSWKYSPN 804 G A S A E G G SP P L P +W P Sbjct: 886 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP- 944 Query: 805 IRAPP---------PIAYNPLLSPFFPQAARTLPKAQSQGPR-ATPKQGIKALD 848 APP P+ + P P T+ +++GP ATP G ALD Sbjct: 945 --APPLAFRGAPGAPLPWPPATGPGSADGLCTI--YETEGPESATPAPG--ALD 992 Score = 90.1 bits (222), Expect = 9e-18 Identities = 183/801 (22%), Positives = 250/801 (31%), Gaps = 137/801 (17%) Query: 96 PSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPR 155 P P LQ L P P AP PL L +P S T+ +P Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS--------------GTKARPV 317 Query: 156 RPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPA 215 P T P P PP S A P P P PS S + PS Q PP+ Sbjct: 318 PPPDNAAT-PLPATLPP-----SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371 Query: 216 EALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKT 275 + P P IP + VPH + + LQ SL +++ Sbjct: 372 --MTTPPMQAPPSLQTIPPI-QVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH- 427 Query: 276 KCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESEL 335 S LT +P + T S + + + D P + L Sbjct: 428 ------SFLTMSP------------------RQTQASLTSPSRPASTPPDSPPLQAPLSL 463 Query: 336 DEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQR 395 S SP L S AS + L + L Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523 Query: 396 QRADSST-----QELARVEP------AAMLNGEGLQSPPRAQ----SAPPEAAVLPPSPL 440 Q +S + L + P +A L L++PP APP PP Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583 Query: 441 PAPVASPRPFQPGGGAPTPAPSIFNRSARPFT------------PGLQGQRPTTTSVIFR 488 P+ +A+P P P A P + + P P LQ S Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643 Query: 489 PLA---PKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVT 545 PLA P+ N L AP S P+P P+ PVS S + P + P Sbjct: 644 PLATPSPQAPNALAVHLLQAP----FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699 Query: 546 ATSSLYIPAP---SRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPG 602 A L +P S P++P P P APP AA P P++ P +P+ P Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP-----PSPPASPPMSPSATPP 754 Query: 603 APEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEK 662 PP + VP + L + + +P + P L +L Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPMS-------PLAKPPPQAPPALATPPLQAL-----PS 802 Query: 663 PRAGGAESGPEEDALSLG----AEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMT 718 P A P + SL A PV A +P P +P AP+ PP Sbjct: 803 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 862 Query: 719 PKT---------------PPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFA 763 P T PPP + P S L ++S+ PE R G E A Sbjct: 863 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA 922 Query: 764 KRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNP-------- 815 D + P R P+P P +++ +P P P A P Sbjct: 923 AASPPPDAELAACHPAAW----SRGPAP----PLAFRGAPGAPLPWPPATGPGSADGLCT 974 Query: 816 LLSPFFPQAARTLPKAQSQGP 836 + P++A P A GP Sbjct: 975 IYETEGPESATPAPGALDPGP 995 Score = 78.2 bits (191), Expect = 4e-14 Identities = 132/542 (24%), Positives = 189/542 (34%), Gaps = 97/542 (17%) Query: 424 RAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTT 483 + A AA P+ + +PRP G+P P P P TP Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRP----PGSPRPPP--------PVTPAALRVLGAAG 51 Query: 484 SVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRS--S 541 +V +PLA + GG+ A P P P+ ++G S P S P++ R + Sbjct: 52 AVGRKPLAERA-----GGIGGATIP---ESAPRAGPTRSAGTSSRNPASRPPASGRGERA 103 Query: 542 GPVTATSSLYIPAPSRP---VTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPS----ARP 594 P TS + +P R PG + SA + AP R + AR Sbjct: 104 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA-TEAPKRSALSAGARR 162 Query: 595 EAPAPGPGAPEPPSAREQR-----ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN 649 + P PG P P AR R + +P G RK + E + P+ Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV-SSASEHSTTEPS 221 Query: 650 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 709 P +P AGG P +LS A + G + TP+ P Sbjct: 222 PA-------ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA-----RGTPRAPAHP 269 Query: 710 APKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRA 769 + P + PP V PP + L ++S P P Sbjct: 270 SQPKPKGLQALRPPQVT--PPRKDAAPALGPLSSSPLATPSP------------------ 309 Query: 770 DRYVVEGTPGPGLGPRPRSPSPTP-SLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTL 828 GT + P + +P P +LPP SP + P P+A SP P + +TL Sbjct: 310 -----SGTKARPVPPPDNAATPLPATLPP----SPPLATPLPLAPP---SPSAPPSLQTL 357 Query: 829 PKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIR 888 P P ATP +A M P Q ++ +PP P + SP Sbjct: 358 P-----SPPATPPS--QAPPSMTTPPMQAPPSL---QTIPPIQVPHSLTSPSLQAPPSPL 407 Query: 889 RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELAS----APVPSPAPPPEAPRGLGA 944 S + Q T +PT+ A + T+ + L S A P +PP +AP L A Sbjct: 408 ALS--SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465 Query: 945 SP 946 SP Sbjct: 466 SP 467 Score = 65.5 bits (158), Expect = 2e-10 Identities = 113/443 (25%), Positives = 160/443 (36%), Gaps = 89/443 (20%) Query: 541 SGPVTATSSLYIPAPSRPVTPGGA-PEPPAPPSAAAMTSTASIFLSAPLRPSAR------ 593 +G T + P P PG P PP P+A + A PL A Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69 Query: 594 -PE-APAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNP- 650 PE AP GP S+R PA+ G + + + PG+ P P Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129 Query: 651 ELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPP-M 709 L + +E G A P+ ALS GA + TP TP P M Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGAR-------------RDTSGPTPGTPSPAM 176 Query: 710 APKTPPPMT----PKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKR 765 A ++ T P+ P P+PP+ G + + + S P P A+R Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA----------ARR 226 Query: 766 QSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAA 825 + A G GL RP S S + S P S R+ P +A Sbjct: 227 RPSA---------GGGL-QRPASRSLSSSATP---LSSPARSGP--------------SA 259 Query: 826 RTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQ 885 R P+A + + PK G++AL +P Q+ + P GP++S SP Sbjct: 260 RGTPRAPAHPSQPKPK-GLQAL-----RPPQVTPPR---KDAAPALGPLSS-SP------ 303 Query: 886 EIRRFSTPAPQPT-AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGA 944 +TP+P T A P+ P AAT L + + + P+P P P AP L Sbjct: 304 ----LATPSPSGTKARPVPPP---DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356 Query: 945 SPSSCGFQVARPRFSATRTGLQA 967 PS ++ S T +QA Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQA 379 Score = 53.9 bits (128), Expect = 7e-07 Identities = 111/461 (24%), Positives = 144/461 (31%), Gaps = 94/461 (20%) Query: 92 PVQSP-SPHELQVLSPLSPLSPEPPGAPVPQPLQ-PGSLRSPPDSEAYYGETDSDADGP- 148 P+Q+P SP LSPL+ SP+ P A LQ P S P +A + S P Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688 Query: 149 ATQEKPRRPRRRGP---TRPTPPGAPPDEVYLSDSPAEP----APTIPGPPSQGDSRVSS 201 AT P P P+PP +PP + P P AP + PPS S S Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748 Query: 202 PSWED---------GAALQPPPAEALLLPHGPL-RPGPHLIPMVGPVPHPVAEDLTTTYT 251 PS LQ PP+ LP PL +P P P + P + L + Sbjct: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT---PPLQALPSPPA 805 Query: 252 QKAKQAKLQRAESLQEKSIKEAKTKCRTI--ASLLTAAPNPHSKGVLMFKKRRQRAKKYT 309 QA + SL + + + A LL P+P + L +R T Sbjct: 806 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 865 Query: 310 LVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRAS 369 VS T A PP S S +S Sbjct: 866 SVS--GPRLTLALAPGPPPPPSRSP---------------------------------SS 890 Query: 370 EGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAP 429 G L G S +ST E R + G PP A+ A Sbjct: 891 TLSGPDLAGHSSSA----------------TSTPEELRGYDSGPEGGAAASPPPDAELAA 934 Query: 430 PEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRP 489 A P P P F+ GAP P P P I+ Sbjct: 935 CHPAAWSRGPAP-----PLAFRGAPGAPLPWP-----------PATGPGSADGLCTIYET 978 Query: 490 LAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAP 530 P+ A + G L P P P + G +G S +P Sbjct: 979 EGPESATPAPGALDPGPSP--GTSGGKAAAGAGAGASSRSP 1017 Score = 35.8 bits (81), Expect = 0.20 Identities = 50/180 (27%), Positives = 65/180 (36%), Gaps = 42/180 (23%) Query: 87 LADEGPVQSPSPH---ELQVLS--PLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGET 141 LA P+ PSP LQ L P +P S PP P P SL++ P + + T Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT 396 Query: 142 DSDADGP---------------------ATQE----KPRRPRRR--GPTRP--TPPGAPP 172 P AT PR+ + P+RP TPP +PP Sbjct: 397 SPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP 456 Query: 173 DEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLI 232 + LS + P T P S +SSP + P A + L H P P LI Sbjct: 457 LQAPLSLPASPPLQTSLSP---AVSPLSSP-----LTIHPLQALSSLASHSPQAPLSSLI 508 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 99.0 bits (245), Expect = 2e-20 Identities = 142/575 (24%), Positives = 201/575 (34%), Gaps = 115/575 (20%) Query: 378 GQLSEVSGRGVQLFEQQRQRADSSTQE-LARVEPAA--MLNGEGLQSPPRAQSAPPE--A 432 G+ S + Q E+ + + T + LA+ P A G L +P P+ A Sbjct: 166 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 225 Query: 433 AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 492 + P P P + S P P APT S P TP + PTTT P P Sbjct: 226 STTPKEPTPTTIKSA-PTTPKEPAPTTTKSA------PTTP--KEPAPTTTKEP-APTTP 275 Query: 493 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 552 K PAP + P P+ T P+ P +P+TP+ P T Sbjct: 276 KE---------PAP-----TTTKEPAPTTTKSAPT-TPKEPAPTTPKKPAPTTPKE---- 316 Query: 553 PAPSRPVTPGGA-PEPPAPPSAA-AMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPS 608 PAP+ P P P+ PAP + A T+ +AP +P+ P+ PAP P P P + Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376 Query: 609 AREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGA 668 +E + P P TK++P ++P Sbjct: 377 TKEPSPTTPK-------------------EPAPTTTKSAPTTT---------KEPAPTTT 408 Query: 669 ESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPK 728 +S P +P + + P TPK P P PK P P TPK P P PK Sbjct: 409 KSAPTTPK-----------EPSPTTTKEPAP-TTPKEPAPTTPKKPAPTTPKEPAPTTPK 456 Query: 729 PPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS 788 P A ++ P P + + + + TP P Sbjct: 457 EP-----------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505 Query: 789 PSPTP--SLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKA 846 P+PT L P+ P P A P P+AA P + TPK+ Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPA------PTTPKAAA--PNTPKEPAPTTPKEPA-- 555 Query: 847 LDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ-PTAEPLAPT 905 P K + P TP A +PK ++ + P+ P + LAPT Sbjct: 556 -------PTTPK------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 602 Query: 906 VLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPR 940 +TT D+P T +AP P P P+ Sbjct: 603 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 637 Score = 90.1 bits (222), Expect = 9e-18 Identities = 144/558 (25%), Positives = 200/558 (35%), Gaps = 77/558 (13%) Query: 395 RQRADSSTQELARV---EPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQ 451 ++ A ++T+E A EPA E +P +SAP P P P P P Sbjct: 260 KEPAPTTTKEPAPTTPKEPAPTTTKE--PAPTTTKSAP----TTPKEPAPTTPKKPAPTT 313 Query: 452 PGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 511 P APT + + P + PTT P APK+ + +P P + Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTAPKKPAPT----TPKEPAPTT 368 Query: 512 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 571 + P P T+ PS P+TP+ P T S+ P T AP P P Sbjct: 369 PKEPAPT---TTKEPS-------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 418 Query: 572 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 629 S T+T + P P+ P+ PAP P P P + +E + + Sbjct: 419 SP---TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475 Query: 630 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM-- 687 T K+ P + PE L EKP A + PEE A + E Sbjct: 476 PTTPKET-APTTPKKLTPTTPE--KLAPTTPEKP----APTTPEELAPTTPEEPTPTTPE 528 Query: 688 QPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG 747 +P P+ TPK P P PK P P TPK P P PK + G A ++ Sbjct: 529 EPAPTTPKAAAPN-TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---APTTLK 584 Query: 748 IPEPPRLQGRGGELFAKRQSRADRYVVEGTPGP----GLGP-RPRSPSPTPSLPPSWKYS 802 P P + + A ++ P P G P P+ P+PT P+ + Sbjct: 585 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-PTT 643 Query: 803 PNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMF 862 P AP + +P P A + L ++GP +T + P K Sbjct: 644 PKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSD--------KPAPTTPK---- 690 Query: 863 CFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEP--IW 920 + P TP A +PK PAP T E PT TT EP I Sbjct: 691 --ETAPTTPKEPAPTTPK-----------KPAP-TTPETPPPTTSEVSTPTTTKEPTTIH 736 Query: 921 RTELASAPVPSPAPPPEA 938 ++ S P S P P+A Sbjct: 737 KSPDESTPELSAEPTPKA 754 Score = 85.1 bits (209), Expect = 3e-16 Identities = 179/842 (21%), Positives = 267/842 (31%), Gaps = 137/842 (16%) Query: 150 TQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAA 209 T K P + +PTP + +P EP PT P P+ + +P+ A Sbjct: 182 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 241 Query: 210 L---QPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKA----KQAKLQRA 262 +P P P P P P P P E TT + A K A Sbjct: 242 TTPKEPAPTTTKSAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 299 Query: 263 ESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAE 322 E K A T + A P P + K+ K+ + A T + Sbjct: 300 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-----KEPAPTTKEPAPTTPKEPAPTAPK 354 Query: 323 EEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSE 382 + P T + A + T + SP E A +++ Sbjct: 355 KP--APTTPKEPAPTTPKEPAPTTTKE---PSPTTPKEPAPTTTKS-------------- 395 Query: 383 VSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPA 442 A ++T+E A P + P + A P P P Sbjct: 396 ---------------APTTTKEPA---PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 437 Query: 443 PVASPRPFQPGGGAPT----PAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDS 498 P P P APT PAP+ + A P TP + PTT P PK+ Sbjct: 438 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPA-PTTP--KEPAPTTPKET-APTTPKK---- 489 Query: 499 LGGLSPAPPPFLSSQGP-TPLPSFTSGVPSHAPVSGSPSTPRSSGPVT----ATSSLYIP 553 L+P P L+ P P P+ + P +P+TP P T A ++ P Sbjct: 490 ---LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 546 Query: 554 APSRPVTPG-GAPEPPAP--PSAAAMTS---TASIFLSAPLRPSARPEAPAP---GPGAP 604 AP+ P P P+ PAP P A T+ TA L P P+ PAP P Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP--APTTPKKPAPKELAPTTT 604 Query: 605 EPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPR 664 + P++ P G + P K + L +KP Sbjct: 605 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP- 663 Query: 665 AGGAESGPEEDA--LSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP 722 P+E A + G + +P +T P TPK P P PK P P TP+TP Sbjct: 664 ------APKELAPTTTKGPTSTTSDKPAPTTPKETAP-TTPKEPAPTTPKKPAPTTPETP 716 Query: 723 PPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGL 782 PP + ++ EP + E + + +E +P Sbjct: 717 PPTTSE-------------VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 763 Query: 783 GPRPRSPSPT-PSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPK 841 P ++P+ T P + + K R +P + T + ++ Sbjct: 764 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 823 Query: 842 QGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEP 901 + + P+++ T T P + + KT EI P+ TA+P Sbjct: 824 TQVTSTTTQDTTPFKITTLK------TTTLAPKVTTTKKTITTTEIMN----KPEETAKP 873 Query: 902 LAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRFSAT 961 R + A P P P +AP+ P+S PR Sbjct: 874 KD-----------------RATNSKATTPKPQKPTKAPK----KPTSTKKPKTMPRVRKP 912 Query: 962 RT 963 +T Sbjct: 913 KT 914 Score = 68.6 bits (166), Expect = 3e-11 Identities = 129/564 (22%), Positives = 185/564 (32%), Gaps = 90/564 (15%) Query: 94 QSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQE- 152 + P+P + +P +P P P P P P + P P T+E Sbjct: 299 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP---KEP---------------APTTKEP 340 Query: 153 KPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGA---A 209 P P+ PT P P + +P EPAPT PS + +P+ A Sbjct: 341 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400 Query: 210 LQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKS 269 +P P P P P P P P E TT + A + A + + Sbjct: 401 KEPAPTTTKSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-- 456 Query: 270 IKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPP 329 + A T + A P P + + KK T + A T E+ P Sbjct: 457 -EPAPTTTKKPAPTTPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKP---AP 508 Query: 330 TSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQ 389 T+ EL + T + P A A + E + Sbjct: 509 TTPEELAPTTPEEPTPTTP----EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT------ 558 Query: 390 LFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVAS--- 446 ++ A ++ +E A P L+ P P L P+ P ++ Sbjct: 559 ----PKEPAPTTPKETAPTTPKGTA-PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 613 Query: 447 -PRPFQPGGGAPT----PAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG 501 P P P G APT PAP+ A P TP +G PTT P PK+ Sbjct: 614 KPAPTTPKGTAPTTPKEPAPTTPKEPA-PTTP--KGTAPTTLKEP-APTTPKK------- 662 Query: 502 LSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTP 561 PAP P+ T G S +P+TP+ + P T PAP+ P P Sbjct: 663 --PAPKEL--------APTTTKGPTSTTSDKPAPTTPKETAPTTPKE----PAPTTPKKP 708 Query: 562 G-GAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAAR 620 PE P P ++ T T + P P+ P A P A E P Sbjct: 709 APTTPETPPPTTSEVSTPTTT---KEPTTIHKSPDESTPELSAEPTPKALENSPKEP--- 762 Query: 621 TGILQEARRRGTRKQMFRPGKEET 644 G+ T+ +M K++T Sbjct: 763 -GVPTTKTPAATKPEMTTTAKDKT 785 Score = 61.2 bits (147), Expect = 4e-09 Identities = 113/501 (22%), Positives = 159/501 (31%), Gaps = 95/501 (18%) Query: 457 PTPAPSIFNRSARPFTPG-LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP--PPFLSSQ 513 PTP P + + + G + P T++ ++ + ++P P PP + Sbjct: 78 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 137 Query: 514 GPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPP--APP 571 T L + + + G TS+ + + AP A P Sbjct: 138 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 197 Query: 572 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 629 + A T+T L+ P P+ P+ PA P P P + + S P Sbjct: 198 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK----SAPT----------- 242 Query: 630 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQP 689 T K+ P TK++P E A + P+E A + E P Sbjct: 243 --TPKE---PAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTTKEPA----P 288 Query: 690 VGARSYKTLPH----VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASS 745 +S T P TPK P P PK P P TPK P P PK P+ + Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----------PTTK 338 Query: 746 AGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNI 805 P P+ + A + TP P+ P+PT + PS +P Sbjct: 339 EPAPTTPK----------EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 387 Query: 806 RAPPPIAYNPLLS----PFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAM 861 AP P + P ++A T PK S P Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP------------------- 428 Query: 862 FCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWR 921 P P P P +E PAP EP APT A TT EP Sbjct: 429 ----TTPKEPAPTTPKKPAPTTPKE------PAPTTPKEP-APTTTKKPAPTTPKEPAPT 477 Query: 922 TELASAPVPSPAPPPEAPRGL 942 T +AP P P L Sbjct: 478 TPKETAPTTPKKLTPTTPEKL 498 Score = 48.9 bits (115), Expect = 2e-05 Identities = 56/210 (26%), Positives = 84/210 (40%), Gaps = 42/210 (20%) Query: 94 QSPSPHELQVLSPLSPLSPEP--PGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQ 151 + P+P + +P + P P P P P+ L P + + P T + +D PA Sbjct: 637 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP---------TSTTSDKPA-- 685 Query: 152 EKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSP-SWEDGAAL 210 P P+ PT P P AP +P +PAPT P P S VS+P + ++ + Sbjct: 686 --PTTPKETAPTTPKEP-AP-------TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 735 Query: 211 QPPPAEAL----------LLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQ 260 P E+ L + P PG +P P ++TTT K + L+ Sbjct: 736 HKSPDESTPELSAEPTPKALENSPKEPG---VPTT-KTPAATKPEMTTTAKDKTTERDLR 791 Query: 261 ---RAESLQEKSIKE-AKTKCRTIASLLTA 286 + K KE A T +T S +TA Sbjct: 792 TTPETTTAAPKMTKETATTTEKTTESKITA 821 Score = 44.7 bits (104), Expect = 4e-04 Identities = 48/193 (24%), Positives = 68/193 (35%), Gaps = 26/193 (13%) Query: 105 SPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTR 164 +P +P P P P P P + P + T + T+ P P+ PT Sbjct: 255 APTTPKEPAPTTTKEPAPTTP---KEPAPT------TTKEPAPTTTKSAPTTPKEPAPTT 305 Query: 165 PTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQP----PPAEALLL 220 P P AP +P EPAPT P P+ + +P+ ++ A P P A Sbjct: 306 PKKP-APT-------TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357 Query: 221 PHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQE---KSIKEAKTKC 277 P P P P P P E TT + A + +E + K A T Sbjct: 358 PTTPKEPAP--TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415 Query: 278 RTIASLLTAAPNP 290 + + T P P Sbjct: 416 KEPSPTTTKEPAP 428 Score = 42.7 bits (99), Expect = 0.002 Identities = 41/172 (23%), Positives = 60/172 (34%), Gaps = 11/172 (6%) Query: 83 TVQRLADEGPVQSPSPHELQVLSPLSP-----LSPEPPGAPVPQPLQPGSLRSPPDSEAY 137 T ++LA P + P+P + L+P +P +PE P P+ P + + P + Sbjct: 494 TPEKLAPTTP-EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 552 Query: 138 YGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDS 197 + + T K P T PT P +P E APT P+ Sbjct: 553 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 612 Query: 198 RVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTT 249 +P+ G A P A P P P G P + E TT Sbjct: 613 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAPTTLKEPAPTT 659 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 99.0 bits (245), Expect = 2e-20 Identities = 142/575 (24%), Positives = 201/575 (34%), Gaps = 115/575 (20%) Query: 378 GQLSEVSGRGVQLFEQQRQRADSSTQE-LARVEPAA--MLNGEGLQSPPRAQSAPPE--A 432 G+ S + Q E+ + + T + LA+ P A G L +P P+ A Sbjct: 207 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 266 Query: 433 AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 492 + P P P + S P P APT S P TP + PTTT P P Sbjct: 267 STTPKEPTPTTIKSA-PTTPKEPAPTTTKSA------PTTP--KEPAPTTTKEP-APTTP 316 Query: 493 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 552 K PAP + P P+ T P+ P +P+TP+ P T Sbjct: 317 KE---------PAP-----TTTKEPAPTTTKSAPT-TPKEPAPTTPKKPAPTTPKE---- 357 Query: 553 PAPSRPVTPGGA-PEPPAPPSAA-AMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPS 608 PAP+ P P P+ PAP + A T+ +AP +P+ P+ PAP P P P + Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417 Query: 609 AREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGA 668 +E + P P TK++P ++P Sbjct: 418 TKEPSPTTPK-------------------EPAPTTTKSAPTTT---------KEPAPTTT 449 Query: 669 ESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPK 728 +S P +P + + P TPK P P PK P P TPK P P PK Sbjct: 450 KSAPTTPK-----------EPSPTTTKEPAP-TTPKEPAPTTPKKPAPTTPKEPAPTTPK 497 Query: 729 PPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS 788 P A ++ P P + + + + TP P Sbjct: 498 EP-----------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546 Query: 789 PSPTP--SLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKA 846 P+PT L P+ P P A P P+AA P + TPK+ Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPA------PTTPKAAA--PNTPKEPAPTTPKEPA-- 596 Query: 847 LDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ-PTAEPLAPT 905 P K + P TP A +PK ++ + P+ P + LAPT Sbjct: 597 -------PTTPK------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 643 Query: 906 VLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPR 940 +TT D+P T +AP P P P+ Sbjct: 644 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 678 Score = 90.1 bits (222), Expect = 9e-18 Identities = 144/558 (25%), Positives = 200/558 (35%), Gaps = 77/558 (13%) Query: 395 RQRADSSTQELARV---EPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQ 451 ++ A ++T+E A EPA E +P +SAP P P P P P Sbjct: 301 KEPAPTTTKEPAPTTPKEPAPTTTKE--PAPTTTKSAP----TTPKEPAPTTPKKPAPTT 354 Query: 452 PGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 511 P APT + + P + PTT P APK+ + +P P + Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTAPKKPAPT----TPKEPAPTT 409 Query: 512 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 571 + P P T+ PS P+TP+ P T S+ P T AP P P Sbjct: 410 PKEPAPT---TTKEPS-------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 459 Query: 572 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 629 S T+T + P P+ P+ PAP P P P + +E + + Sbjct: 460 SP---TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 516 Query: 630 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM-- 687 T K+ P + PE L EKP A + PEE A + E Sbjct: 517 PTTPKET-APTTPKKLTPTTPE--KLAPTTPEKP----APTTPEELAPTTPEEPTPTTPE 569 Query: 688 QPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG 747 +P P+ TPK P P PK P P TPK P P PK + G A ++ Sbjct: 570 EPAPTTPKAAAPN-TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---APTTLK 625 Query: 748 IPEPPRLQGRGGELFAKRQSRADRYVVEGTPGP----GLGP-RPRSPSPTPSLPPSWKYS 802 P P + + A ++ P P G P P+ P+PT P+ + Sbjct: 626 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-PTT 684 Query: 803 PNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMF 862 P AP + +P P A + L ++GP +T + P K Sbjct: 685 PKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSD--------KPAPTTPK---- 731 Query: 863 CFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEP--IW 920 + P TP A +PK PAP T E PT TT EP I Sbjct: 732 --ETAPTTPKEPAPTTPK-----------KPAP-TTPETPPPTTSEVSTPTTTKEPTTIH 777 Query: 921 RTELASAPVPSPAPPPEA 938 ++ S P S P P+A Sbjct: 778 KSPDESTPELSAEPTPKA 795 Score = 85.1 bits (209), Expect = 3e-16 Identities = 179/842 (21%), Positives = 267/842 (31%), Gaps = 137/842 (16%) Query: 150 TQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAA 209 T K P + +PTP + +P EP PT P P+ + +P+ A Sbjct: 223 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 282 Query: 210 L---QPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKA----KQAKLQRA 262 +P P P P P P P P E TT + A K A Sbjct: 283 TTPKEPAPTTTKSAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 340 Query: 263 ESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAE 322 E K A T + A P P + K+ K+ + A T + Sbjct: 341 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-----KEPAPTTKEPAPTTPKEPAPTAPK 395 Query: 323 EEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSE 382 + P T + A + T + SP E A +++ Sbjct: 396 KP--APTTPKEPAPTTPKEPAPTTTKE---PSPTTPKEPAPTTTKS-------------- 436 Query: 383 VSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPA 442 A ++T+E A P + P + A P P P Sbjct: 437 ---------------APTTTKEPA---PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 478 Query: 443 PVASPRPFQPGGGAPT----PAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDS 498 P P P APT PAP+ + A P TP + PTT P PK+ Sbjct: 479 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPA-PTTP--KEPAPTTPKET-APTTPKK---- 530 Query: 499 LGGLSPAPPPFLSSQGP-TPLPSFTSGVPSHAPVSGSPSTPRSSGPVT----ATSSLYIP 553 L+P P L+ P P P+ + P +P+TP P T A ++ P Sbjct: 531 ---LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 587 Query: 554 APSRPVTPG-GAPEPPAP--PSAAAMTS---TASIFLSAPLRPSARPEAPAP---GPGAP 604 AP+ P P P+ PAP P A T+ TA L P P+ PAP P Sbjct: 588 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP--APTTPKKPAPKELAPTTT 645 Query: 605 EPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPR 664 + P++ P G + P K + L +KP Sbjct: 646 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP- 704 Query: 665 AGGAESGPEEDA--LSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP 722 P+E A + G + +P +T P TPK P P PK P P TP+TP Sbjct: 705 ------APKELAPTTTKGPTSTTSDKPAPTTPKETAP-TTPKEPAPTTPKKPAPTTPETP 757 Query: 723 PPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGL 782 PP + ++ EP + E + + +E +P Sbjct: 758 PPTTSE-------------VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 804 Query: 783 GPRPRSPSPT-PSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPK 841 P ++P+ T P + + K R +P + T + ++ Sbjct: 805 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 864 Query: 842 QGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEP 901 + + P+++ T T P + + KT EI P+ TA+P Sbjct: 865 TQVTSTTTQDTTPFKITTLK------TTTLAPKVTTTKKTITTTEIMN----KPEETAKP 914 Query: 902 LAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRFSAT 961 R + A P P P +AP+ P+S PR Sbjct: 915 KD-----------------RATNSKATTPKPQKPTKAPK----KPTSTKKPKTMPRVRKP 953 Query: 962 RT 963 +T Sbjct: 954 KT 955 Score = 68.6 bits (166), Expect = 3e-11 Identities = 129/564 (22%), Positives = 185/564 (32%), Gaps = 90/564 (15%) Query: 94 QSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQE- 152 + P+P + +P +P P P P P P + P P T+E Sbjct: 340 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP---KEP---------------APTTKEP 381 Query: 153 KPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGA---A 209 P P+ PT P P + +P EPAPT PS + +P+ A Sbjct: 382 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441 Query: 210 LQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKS 269 +P P P P P P P P E TT + A + A + + Sbjct: 442 KEPAPTTTKSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-- 497 Query: 270 IKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPP 329 + A T + A P P + + KK T + A T E+ P Sbjct: 498 -EPAPTTTKKPAPTTPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKP---AP 549 Query: 330 TSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQ 389 T+ EL + T + P A A + E + Sbjct: 550 TTPEELAPTTPEEPTPTTP----EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT------ 599 Query: 390 LFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVAS--- 446 ++ A ++ +E A P L+ P P L P+ P ++ Sbjct: 600 ----PKEPAPTTPKETAPTTPKGTA-PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 654 Query: 447 -PRPFQPGGGAPT----PAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG 501 P P P G APT PAP+ A P TP +G PTT P PK+ Sbjct: 655 KPAPTTPKGTAPTTPKEPAPTTPKEPA-PTTP--KGTAPTTLKEP-APTTPKK------- 703 Query: 502 LSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTP 561 PAP P+ T G S +P+TP+ + P T PAP+ P P Sbjct: 704 --PAPKEL--------APTTTKGPTSTTSDKPAPTTPKETAPTTPKE----PAPTTPKKP 749 Query: 562 G-GAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAAR 620 PE P P ++ T T + P P+ P A P A E P Sbjct: 750 APTTPETPPPTTSEVSTPTTT---KEPTTIHKSPDESTPELSAEPTPKALENSPKEP--- 803 Query: 621 TGILQEARRRGTRKQMFRPGKEET 644 G+ T+ +M K++T Sbjct: 804 -GVPTTKTPAATKPEMTTTAKDKT 826 Score = 61.2 bits (147), Expect = 4e-09 Identities = 113/501 (22%), Positives = 159/501 (31%), Gaps = 95/501 (18%) Query: 457 PTPAPSIFNRSARPFTPG-LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP--PPFLSSQ 513 PTP P + + + G + P T++ ++ + ++P P PP + Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 178 Query: 514 GPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPP--APP 571 T L + + + G TS+ + + AP A P Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 238 Query: 572 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 629 + A T+T L+ P P+ P+ PA P P P + + S P Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK----SAPT----------- 283 Query: 630 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQP 689 T K+ P TK++P E A + P+E A + E P Sbjct: 284 --TPKE---PAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTTKEPA----P 329 Query: 690 VGARSYKTLPH----VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASS 745 +S T P TPK P P PK P P TPK P P PK P+ + Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----------PTTK 379 Query: 746 AGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNI 805 P P+ + A + TP P+ P+PT + PS +P Sbjct: 380 EPAPTTPK----------EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 428 Query: 806 RAPPPIAYNPLLS----PFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAM 861 AP P + P ++A T PK S P Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP------------------- 469 Query: 862 FCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWR 921 P P P P +E PAP EP APT A TT EP Sbjct: 470 ----TTPKEPAPTTPKKPAPTTPKE------PAPTTPKEP-APTTTKKPAPTTPKEPAPT 518 Query: 922 TELASAPVPSPAPPPEAPRGL 942 T +AP P P L Sbjct: 519 TPKETAPTTPKKLTPTTPEKL 539 Score = 48.9 bits (115), Expect = 2e-05 Identities = 56/210 (26%), Positives = 84/210 (40%), Gaps = 42/210 (20%) Query: 94 QSPSPHELQVLSPLSPLSPEP--PGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQ 151 + P+P + +P + P P P P P+ L P + + P T + +D PA Sbjct: 678 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP---------TSTTSDKPA-- 726 Query: 152 EKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSP-SWEDGAAL 210 P P+ PT P P AP +P +PAPT P P S VS+P + ++ + Sbjct: 727 --PTTPKETAPTTPKEP-AP-------TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 776 Query: 211 QPPPAEAL----------LLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQ 260 P E+ L + P PG +P P ++TTT K + L+ Sbjct: 777 HKSPDESTPELSAEPTPKALENSPKEPG---VPTT-KTPAATKPEMTTTAKDKTTERDLR 832 Query: 261 ---RAESLQEKSIKE-AKTKCRTIASLLTA 286 + K KE A T +T S +TA Sbjct: 833 TTPETTTAAPKMTKETATTTEKTTESKITA 862 Score = 44.7 bits (104), Expect = 4e-04 Identities = 48/193 (24%), Positives = 68/193 (35%), Gaps = 26/193 (13%) Query: 105 SPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTR 164 +P +P P P P P P + P + T + T+ P P+ PT Sbjct: 296 APTTPKEPAPTTTKEPAPTTP---KEPAPT------TTKEPAPTTTKSAPTTPKEPAPTT 346 Query: 165 PTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQP----PPAEALLL 220 P P AP +P EPAPT P P+ + +P+ ++ A P P A Sbjct: 347 PKKP-APT-------TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398 Query: 221 PHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQE---KSIKEAKTKC 277 P P P P P P E TT + A + +E + K A T Sbjct: 399 PTTPKEPAP--TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456 Query: 278 RTIASLLTAAPNP 290 + + T P P Sbjct: 457 KEPSPTTTKEPAP 469 Score = 42.7 bits (99), Expect = 0.002 Identities = 41/172 (23%), Positives = 60/172 (34%), Gaps = 11/172 (6%) Query: 83 TVQRLADEGPVQSPSPHELQVLSPLSP-----LSPEPPGAPVPQPLQPGSLRSPPDSEAY 137 T ++LA P + P+P + L+P +P +PE P P+ P + + P + Sbjct: 535 TPEKLAPTTP-EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 593 Query: 138 YGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDS 197 + + T K P T PT P +P E APT P+ Sbjct: 594 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 653 Query: 198 RVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTT 249 +P+ G A P A P P P G P + E TT Sbjct: 654 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAPTTLKEPAPTT 700 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 99.0 bits (245), Expect = 2e-20 Identities = 142/575 (24%), Positives = 201/575 (34%), Gaps = 115/575 (20%) Query: 378 GQLSEVSGRGVQLFEQQRQRADSSTQE-LARVEPAA--MLNGEGLQSPPRAQSAPPE--A 432 G+ S + Q E+ + + T + LA+ P A G L +P P+ A Sbjct: 259 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 318 Query: 433 AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 492 + P P P + S P P APT S P TP + PTTT P P Sbjct: 319 STTPKEPTPTTIKSA-PTTPKEPAPTTTKSA------PTTP--KEPAPTTTKEP-APTTP 368 Query: 493 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 552 K PAP + P P+ T P+ P +P+TP+ P T Sbjct: 369 KE---------PAP-----TTTKEPAPTTTKSAPT-TPKEPAPTTPKKPAPTTPKE---- 409 Query: 553 PAPSRPVTPGGA-PEPPAPPSAA-AMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPS 608 PAP+ P P P+ PAP + A T+ +AP +P+ P+ PAP P P P + Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469 Query: 609 AREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGA 668 +E + P P TK++P ++P Sbjct: 470 TKEPSPTTPK-------------------EPAPTTTKSAPTTT---------KEPAPTTT 501 Query: 669 ESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPK 728 +S P +P + + P TPK P P PK P P TPK P P PK Sbjct: 502 KSAPTTPK-----------EPSPTTTKEPAP-TTPKEPAPTTPKKPAPTTPKEPAPTTPK 549 Query: 729 PPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS 788 P A ++ P P + + + + TP P Sbjct: 550 EP-----------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 598 Query: 789 PSPTP--SLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKA 846 P+PT L P+ P P A P P+AA P + TPK+ Sbjct: 599 PAPTTPEELAPTTPEEPTPTTPEEPA------PTTPKAAA--PNTPKEPAPTTPKEPA-- 648 Query: 847 LDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ-PTAEPLAPT 905 P K + P TP A +PK ++ + P+ P + LAPT Sbjct: 649 -------PTTPK------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 695 Query: 906 VLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPR 940 +TT D+P T +AP P P P+ Sbjct: 696 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 730 Score = 90.1 bits (222), Expect = 9e-18 Identities = 144/558 (25%), Positives = 200/558 (35%), Gaps = 77/558 (13%) Query: 395 RQRADSSTQELARV---EPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQ 451 ++ A ++T+E A EPA E +P +SAP P P P P P Sbjct: 353 KEPAPTTTKEPAPTTPKEPAPTTTKE--PAPTTTKSAP----TTPKEPAPTTPKKPAPTT 406 Query: 452 PGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 511 P APT + + P + PTT P APK+ + +P P + Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTAPKKPAPT----TPKEPAPTT 461 Query: 512 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 571 + P P T+ PS P+TP+ P T S+ P T AP P P Sbjct: 462 PKEPAPT---TTKEPS-------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511 Query: 572 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 629 S T+T + P P+ P+ PAP P P P + +E + + Sbjct: 512 SP---TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 568 Query: 630 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM-- 687 T K+ P + PE L EKP A + PEE A + E Sbjct: 569 PTTPKET-APTTPKKLTPTTPE--KLAPTTPEKP----APTTPEELAPTTPEEPTPTTPE 621 Query: 688 QPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG 747 +P P+ TPK P P PK P P TPK P P PK + G A ++ Sbjct: 622 EPAPTTPKAAAPN-TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---APTTLK 677 Query: 748 IPEPPRLQGRGGELFAKRQSRADRYVVEGTPGP----GLGP-RPRSPSPTPSLPPSWKYS 802 P P + + A ++ P P G P P+ P+PT P+ + Sbjct: 678 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-PTT 736 Query: 803 PNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMF 862 P AP + +P P A + L ++GP +T + P K Sbjct: 737 PKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSD--------KPAPTTPK---- 783 Query: 863 CFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEP--IW 920 + P TP A +PK PAP T E PT TT EP I Sbjct: 784 --ETAPTTPKEPAPTTPK-----------KPAP-TTPETPPPTTSEVSTPTTTKEPTTIH 829 Query: 921 RTELASAPVPSPAPPPEA 938 ++ S P S P P+A Sbjct: 830 KSPDESTPELSAEPTPKA 847 Score = 85.1 bits (209), Expect = 3e-16 Identities = 179/842 (21%), Positives = 267/842 (31%), Gaps = 137/842 (16%) Query: 150 TQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAA 209 T K P + +PTP + +P EP PT P P+ + +P+ A Sbjct: 275 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 334 Query: 210 L---QPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKA----KQAKLQRA 262 +P P P P P P P P E TT + A K A Sbjct: 335 TTPKEPAPTTTKSAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 392 Query: 263 ESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAE 322 E K A T + A P P + K+ K+ + A T + Sbjct: 393 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-----KEPAPTTKEPAPTTPKEPAPTAPK 447 Query: 323 EEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSE 382 + P T + A + T + SP E A +++ Sbjct: 448 KP--APTTPKEPAPTTPKEPAPTTTKE---PSPTTPKEPAPTTTKS-------------- 488 Query: 383 VSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPA 442 A ++T+E A P + P + A P P P Sbjct: 489 ---------------APTTTKEPA---PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 530 Query: 443 PVASPRPFQPGGGAPT----PAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDS 498 P P P APT PAP+ + A P TP + PTT P PK+ Sbjct: 531 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPA-PTTP--KEPAPTTPKET-APTTPKK---- 582 Query: 499 LGGLSPAPPPFLSSQGP-TPLPSFTSGVPSHAPVSGSPSTPRSSGPVT----ATSSLYIP 553 L+P P L+ P P P+ + P +P+TP P T A ++ P Sbjct: 583 ---LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 639 Query: 554 APSRPVTPG-GAPEPPAP--PSAAAMTS---TASIFLSAPLRPSARPEAPAP---GPGAP 604 AP+ P P P+ PAP P A T+ TA L P P+ PAP P Sbjct: 640 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP--APTTPKKPAPKELAPTTT 697 Query: 605 EPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPR 664 + P++ P G + P K + L +KP Sbjct: 698 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP- 756 Query: 665 AGGAESGPEEDA--LSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP 722 P+E A + G + +P +T P TPK P P PK P P TP+TP Sbjct: 757 ------APKELAPTTTKGPTSTTSDKPAPTTPKETAP-TTPKEPAPTTPKKPAPTTPETP 809 Query: 723 PPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGL 782 PP + ++ EP + E + + +E +P Sbjct: 810 PPTTSE-------------VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 856 Query: 783 GPRPRSPSPT-PSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPK 841 P ++P+ T P + + K R +P + T + ++ Sbjct: 857 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 916 Query: 842 QGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEP 901 + + P+++ T T P + + KT EI P+ TA+P Sbjct: 917 TQVTSTTTQDTTPFKITTLK------TTTLAPKVTTTKKTITTTEIMN----KPEETAKP 966 Query: 902 LAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRFSAT 961 R + A P P P +AP+ P+S PR Sbjct: 967 KD-----------------RATNSKATTPKPQKPTKAPK----KPTSTKKPKTMPRVRKP 1005 Query: 962 RT 963 +T Sbjct: 1006 KT 1007 Score = 68.6 bits (166), Expect = 3e-11 Identities = 129/564 (22%), Positives = 185/564 (32%), Gaps = 90/564 (15%) Query: 94 QSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQE- 152 + P+P + +P +P P P P P P + P P T+E Sbjct: 392 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP---KEP---------------APTTKEP 433 Query: 153 KPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGA---A 209 P P+ PT P P + +P EPAPT PS + +P+ A Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493 Query: 210 LQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKS 269 +P P P P P P P P E TT + A + A + + Sbjct: 494 KEPAPTTTKSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-- 549 Query: 270 IKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPP 329 + A T + A P P + + KK T + A T E+ P Sbjct: 550 -EPAPTTTKKPAPTTPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKP---AP 601 Query: 330 TSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQ 389 T+ EL + T + P A A + E + Sbjct: 602 TTPEELAPTTPEEPTPTTP----EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT------ 651 Query: 390 LFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVAS--- 446 ++ A ++ +E A P L+ P P L P+ P ++ Sbjct: 652 ----PKEPAPTTPKETAPTTPKGTA-PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 706 Query: 447 -PRPFQPGGGAPT----PAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG 501 P P P G APT PAP+ A P TP +G PTT P PK+ Sbjct: 707 KPAPTTPKGTAPTTPKEPAPTTPKEPA-PTTP--KGTAPTTLKEP-APTTPKK------- 755 Query: 502 LSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTP 561 PAP P+ T G S +P+TP+ + P T PAP+ P P Sbjct: 756 --PAPKEL--------APTTTKGPTSTTSDKPAPTTPKETAPTTPKE----PAPTTPKKP 801 Query: 562 G-GAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAAR 620 PE P P ++ T T + P P+ P A P A E P Sbjct: 802 APTTPETPPPTTSEVSTPTTT---KEPTTIHKSPDESTPELSAEPTPKALENSPKEP--- 855 Query: 621 TGILQEARRRGTRKQMFRPGKEET 644 G+ T+ +M K++T Sbjct: 856 -GVPTTKTPAATKPEMTTTAKDKT 878 Score = 61.2 bits (147), Expect = 4e-09 Identities = 113/501 (22%), Positives = 159/501 (31%), Gaps = 95/501 (18%) Query: 457 PTPAPSIFNRSARPFTPG-LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP--PPFLSSQ 513 PTP P + + + G + P T++ ++ + ++P P PP + Sbjct: 171 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 230 Query: 514 GPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPP--APP 571 T L + + + G TS+ + + AP A P Sbjct: 231 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 290 Query: 572 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 629 + A T+T L+ P P+ P+ PA P P P + + S P Sbjct: 291 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK----SAPT----------- 335 Query: 630 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQP 689 T K+ P TK++P E A + P+E A + E P Sbjct: 336 --TPKE---PAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTTKEPA----P 381 Query: 690 VGARSYKTLPH----VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASS 745 +S T P TPK P P PK P P TPK P P PK P+ + Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----------PTTK 431 Query: 746 AGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNI 805 P P+ + A + TP P+ P+PT + PS +P Sbjct: 432 EPAPTTPK----------EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 480 Query: 806 RAPPPIAYNPLLS----PFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAM 861 AP P + P ++A T PK S P Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP------------------- 521 Query: 862 FCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWR 921 P P P P +E PAP EP APT A TT EP Sbjct: 522 ----TTPKEPAPTTPKKPAPTTPKE------PAPTTPKEP-APTTTKKPAPTTPKEPAPT 570 Query: 922 TELASAPVPSPAPPPEAPRGL 942 T +AP P P L Sbjct: 571 TPKETAPTTPKKLTPTTPEKL 591 Score = 48.9 bits (115), Expect = 2e-05 Identities = 56/210 (26%), Positives = 84/210 (40%), Gaps = 42/210 (20%) Query: 94 QSPSPHELQVLSPLSPLSPEP--PGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQ 151 + P+P + +P + P P P P P+ L P + + P T + +D PA Sbjct: 730 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP---------TSTTSDKPA-- 778 Query: 152 EKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSP-SWEDGAAL 210 P P+ PT P P AP +P +PAPT P P S VS+P + ++ + Sbjct: 779 --PTTPKETAPTTPKEP-AP-------TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 828 Query: 211 QPPPAEAL----------LLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQ 260 P E+ L + P PG +P P ++TTT K + L+ Sbjct: 829 HKSPDESTPELSAEPTPKALENSPKEPG---VPTT-KTPAATKPEMTTTAKDKTTERDLR 884 Query: 261 ---RAESLQEKSIKE-AKTKCRTIASLLTA 286 + K KE A T +T S +TA Sbjct: 885 TTPETTTAAPKMTKETATTTEKTTESKITA 914 Score = 44.7 bits (104), Expect = 4e-04 Identities = 48/193 (24%), Positives = 68/193 (35%), Gaps = 26/193 (13%) Query: 105 SPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTR 164 +P +P P P P P P + P + T + T+ P P+ PT Sbjct: 348 APTTPKEPAPTTTKEPAPTTP---KEPAPT------TTKEPAPTTTKSAPTTPKEPAPTT 398 Query: 165 PTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQP----PPAEALLL 220 P P AP +P EPAPT P P+ + +P+ ++ A P P A Sbjct: 399 PKKP-APT-------TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450 Query: 221 PHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQE---KSIKEAKTKC 277 P P P P P P E TT + A + +E + K A T Sbjct: 451 PTTPKEPAP--TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 508 Query: 278 RTIASLLTAAPNP 290 + + T P P Sbjct: 509 KEPSPTTTKEPAP 521 Score = 42.7 bits (99), Expect = 0.002 Identities = 41/172 (23%), Positives = 60/172 (34%), Gaps = 11/172 (6%) Query: 83 TVQRLADEGPVQSPSPHELQVLSPLSP-----LSPEPPGAPVPQPLQPGSLRSPPDSEAY 137 T ++LA P + P+P + L+P +P +PE P P+ P + + P + Sbjct: 587 TPEKLAPTTP-EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 645 Query: 138 YGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDS 197 + + T K P T PT P +P E APT P+ Sbjct: 646 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 705 Query: 198 RVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTT 249 +P+ G A P A P P P G P + E TT Sbjct: 706 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAPTTLKEPAPTT 752 Score = 30.8 bits (68), Expect = 6.5 Identities = 78/395 (19%), Positives = 116/395 (29%), Gaps = 31/395 (7%) Query: 558 PVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVP 617 P +P + + P PPS A+ T ++ S + + E S E + S Sbjct: 69 PTSPPSSKKAP-PPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 127 Query: 618 AARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDAL 677 ++ + R+ + K N + L + N + + P D Sbjct: 128 SSSSSSSSSTIRK------IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEA 181 Query: 678 SLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP-PPVAPKPPSRGLLD 736 G + +F V T H T P + T P+ P+ PP + L Sbjct: 182 GSGLDNGDFK--VTTPDTSTTQHNKVSTSPKIT--TAKPINPRPSLPPNSDTSKETSLTV 237 Query: 737 GLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS-PSPTPSL 795 + + G E K S + +E T L P + PTP Sbjct: 238 NKETTVETKETTTTNKQTSTDGKE---KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKA 294 Query: 796 PPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPY 855 + K P + P P P P TPK+ P Sbjct: 295 ETTTK-GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP-TTPKEPA---------PT 343 Query: 856 QLKTAMFCFDEVPPT----PGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRA 911 K+A E PT P P P +E +T + T + APT A Sbjct: 344 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403 Query: 912 ATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASP 946 TT EP T P P P +P Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 99.0 bits (245), Expect = 2e-20 Identities = 142/575 (24%), Positives = 201/575 (34%), Gaps = 115/575 (20%) Query: 378 GQLSEVSGRGVQLFEQQRQRADSSTQE-LARVEPAA--MLNGEGLQSPPRAQSAPPE--A 432 G+ S + Q E+ + + T + LA+ P A G L +P P+ A Sbjct: 300 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 359 Query: 433 AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 492 + P P P + S P P APT S P TP + PTTT P P Sbjct: 360 STTPKEPTPTTIKSA-PTTPKEPAPTTTKSA------PTTP--KEPAPTTTKEP-APTTP 409 Query: 493 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 552 K PAP + P P+ T P+ P +P+TP+ P T Sbjct: 410 KE---------PAP-----TTTKEPAPTTTKSAPT-TPKEPAPTTPKKPAPTTPKE---- 450 Query: 553 PAPSRPVTPGGA-PEPPAPPSAA-AMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPS 608 PAP+ P P P+ PAP + A T+ +AP +P+ P+ PAP P P P + Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510 Query: 609 AREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGA 668 +E + P P TK++P ++P Sbjct: 511 TKEPSPTTPK-------------------EPAPTTTKSAPTTT---------KEPAPTTT 542 Query: 669 ESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPK 728 +S P +P + + P TPK P P PK P P TPK P P PK Sbjct: 543 KSAPTTPK-----------EPSPTTTKEPAP-TTPKEPAPTTPKKPAPTTPKEPAPTTPK 590 Query: 729 PPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS 788 P A ++ P P + + + + TP P Sbjct: 591 EP-----------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 639 Query: 789 PSPTP--SLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKA 846 P+PT L P+ P P A P P+AA P + TPK+ Sbjct: 640 PAPTTPEELAPTTPEEPTPTTPEEPA------PTTPKAAA--PNTPKEPAPTTPKEPA-- 689 Query: 847 LDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ-PTAEPLAPT 905 P K + P TP A +PK ++ + P+ P + LAPT Sbjct: 690 -------PTTPK------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 736 Query: 906 VLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPR 940 +TT D+P T +AP P P P+ Sbjct: 737 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 771 Score = 90.1 bits (222), Expect = 9e-18 Identities = 144/558 (25%), Positives = 200/558 (35%), Gaps = 77/558 (13%) Query: 395 RQRADSSTQELARV---EPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQ 451 ++ A ++T+E A EPA E +P +SAP P P P P P Sbjct: 394 KEPAPTTTKEPAPTTPKEPAPTTTKE--PAPTTTKSAP----TTPKEPAPTTPKKPAPTT 447 Query: 452 PGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 511 P APT + + P + PTT P APK+ + +P P + Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTAPKKPAPT----TPKEPAPTT 502 Query: 512 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 571 + P P T+ PS P+TP+ P T S+ P T AP P P Sbjct: 503 PKEPAPT---TTKEPS-------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552 Query: 572 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 629 S T+T + P P+ P+ PAP P P P + +E + + Sbjct: 553 SP---TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 609 Query: 630 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM-- 687 T K+ P + PE L EKP A + PEE A + E Sbjct: 610 PTTPKET-APTTPKKLTPTTPE--KLAPTTPEKP----APTTPEELAPTTPEEPTPTTPE 662 Query: 688 QPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG 747 +P P+ TPK P P PK P P TPK P P PK + G A ++ Sbjct: 663 EPAPTTPKAAAPN-TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---APTTLK 718 Query: 748 IPEPPRLQGRGGELFAKRQSRADRYVVEGTPGP----GLGP-RPRSPSPTPSLPPSWKYS 802 P P + + A ++ P P G P P+ P+PT P+ + Sbjct: 719 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-PTT 777 Query: 803 PNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMF 862 P AP + +P P A + L ++GP +T + P K Sbjct: 778 PKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSD--------KPAPTTPK---- 824 Query: 863 CFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEP--IW 920 + P TP A +PK PAP T E PT TT EP I Sbjct: 825 --ETAPTTPKEPAPTTPK-----------KPAP-TTPETPPPTTSEVSTPTTTKEPTTIH 870 Query: 921 RTELASAPVPSPAPPPEA 938 ++ S P S P P+A Sbjct: 871 KSPDESTPELSAEPTPKA 888 Score = 85.1 bits (209), Expect = 3e-16 Identities = 179/842 (21%), Positives = 267/842 (31%), Gaps = 137/842 (16%) Query: 150 TQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAA 209 T K P + +PTP + +P EP PT P P+ + +P+ A Sbjct: 316 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 375 Query: 210 L---QPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKA----KQAKLQRA 262 +P P P P P P P P E TT + A K A Sbjct: 376 TTPKEPAPTTTKSAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 433 Query: 263 ESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAE 322 E K A T + A P P + K+ K+ + A T + Sbjct: 434 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-----KEPAPTTKEPAPTTPKEPAPTAPK 488 Query: 323 EEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSE 382 + P T + A + T + SP E A +++ Sbjct: 489 KP--APTTPKEPAPTTPKEPAPTTTKE---PSPTTPKEPAPTTTKS-------------- 529 Query: 383 VSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPA 442 A ++T+E A P + P + A P P P Sbjct: 530 ---------------APTTTKEPA---PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 571 Query: 443 PVASPRPFQPGGGAPT----PAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDS 498 P P P APT PAP+ + A P TP + PTT P PK+ Sbjct: 572 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPA-PTTP--KEPAPTTPKET-APTTPKK---- 623 Query: 499 LGGLSPAPPPFLSSQGP-TPLPSFTSGVPSHAPVSGSPSTPRSSGPVT----ATSSLYIP 553 L+P P L+ P P P+ + P +P+TP P T A ++ P Sbjct: 624 ---LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 680 Query: 554 APSRPVTPG-GAPEPPAP--PSAAAMTS---TASIFLSAPLRPSARPEAPAP---GPGAP 604 AP+ P P P+ PAP P A T+ TA L P P+ PAP P Sbjct: 681 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP--APTTPKKPAPKELAPTTT 738 Query: 605 EPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPR 664 + P++ P G + P K + L +KP Sbjct: 739 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP- 797 Query: 665 AGGAESGPEEDA--LSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP 722 P+E A + G + +P +T P TPK P P PK P P TP+TP Sbjct: 798 ------APKELAPTTTKGPTSTTSDKPAPTTPKETAP-TTPKEPAPTTPKKPAPTTPETP 850 Query: 723 PPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGL 782 PP + ++ EP + E + + +E +P Sbjct: 851 PPTTSE-------------VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 897 Query: 783 GPRPRSPSPT-PSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPK 841 P ++P+ T P + + K R +P + T + ++ Sbjct: 898 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 957 Query: 842 QGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEP 901 + + P+++ T T P + + KT EI P+ TA+P Sbjct: 958 TQVTSTTTQDTTPFKITTLK------TTTLAPKVTTTKKTITTTEIMN----KPEETAKP 1007 Query: 902 LAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRFSAT 961 R + A P P P +AP+ P+S PR Sbjct: 1008 KD-----------------RATNSKATTPKPQKPTKAPK----KPTSTKKPKTMPRVRKP 1046 Query: 962 RT 963 +T Sbjct: 1047 KT 1048 Score = 68.6 bits (166), Expect = 3e-11 Identities = 129/564 (22%), Positives = 185/564 (32%), Gaps = 90/564 (15%) Query: 94 QSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQE- 152 + P+P + +P +P P P P P P + P P T+E Sbjct: 433 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP---KEP---------------APTTKEP 474 Query: 153 KPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGA---A 209 P P+ PT P P + +P EPAPT PS + +P+ A Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534 Query: 210 LQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKS 269 +P P P P P P P P E TT + A + A + + Sbjct: 535 KEPAPTTTKSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-- 590 Query: 270 IKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPP 329 + A T + A P P + + KK T + A T E+ P Sbjct: 591 -EPAPTTTKKPAPTTPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKP---AP 642 Query: 330 TSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQ 389 T+ EL + T + P A A + E + Sbjct: 643 TTPEELAPTTPEEPTPTTP----EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT------ 692 Query: 390 LFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVAS--- 446 ++ A ++ +E A P L+ P P L P+ P ++ Sbjct: 693 ----PKEPAPTTPKETAPTTPKGTA-PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 747 Query: 447 -PRPFQPGGGAPT----PAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG 501 P P P G APT PAP+ A P TP +G PTT P PK+ Sbjct: 748 KPAPTTPKGTAPTTPKEPAPTTPKEPA-PTTP--KGTAPTTLKEP-APTTPKK------- 796 Query: 502 LSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTP 561 PAP P+ T G S +P+TP+ + P T PAP+ P P Sbjct: 797 --PAPKEL--------APTTTKGPTSTTSDKPAPTTPKETAPTTPKE----PAPTTPKKP 842 Query: 562 G-GAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAAR 620 PE P P ++ T T + P P+ P A P A E P Sbjct: 843 APTTPETPPPTTSEVSTPTTT---KEPTTIHKSPDESTPELSAEPTPKALENSPKEP--- 896 Query: 621 TGILQEARRRGTRKQMFRPGKEET 644 G+ T+ +M K++T Sbjct: 897 -GVPTTKTPAATKPEMTTTAKDKT 919 Score = 61.2 bits (147), Expect = 4e-09 Identities = 113/501 (22%), Positives = 159/501 (31%), Gaps = 95/501 (18%) Query: 457 PTPAPSIFNRSARPFTPG-LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP--PPFLSSQ 513 PTP P + + + G + P T++ ++ + ++P P PP + Sbjct: 212 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 271 Query: 514 GPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPP--APP 571 T L + + + G TS+ + + AP A P Sbjct: 272 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 331 Query: 572 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 629 + A T+T L+ P P+ P+ PA P P P + + S P Sbjct: 332 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK----SAPT----------- 376 Query: 630 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQP 689 T K+ P TK++P E A + P+E A + E P Sbjct: 377 --TPKE---PAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTTKEPA----P 422 Query: 690 VGARSYKTLPH----VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASS 745 +S T P TPK P P PK P P TPK P P PK P+ + Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----------PTTK 472 Query: 746 AGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNI 805 P P+ + A + TP P+ P+PT + PS +P Sbjct: 473 EPAPTTPK----------EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 521 Query: 806 RAPPPIAYNPLLS----PFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAM 861 AP P + P ++A T PK S P Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP------------------- 562 Query: 862 FCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWR 921 P P P P +E PAP EP APT A TT EP Sbjct: 563 ----TTPKEPAPTTPKKPAPTTPKE------PAPTTPKEP-APTTTKKPAPTTPKEPAPT 611 Query: 922 TELASAPVPSPAPPPEAPRGL 942 T +AP P P L Sbjct: 612 TPKETAPTTPKKLTPTTPEKL 632 Score = 48.9 bits (115), Expect = 2e-05 Identities = 56/210 (26%), Positives = 84/210 (40%), Gaps = 42/210 (20%) Query: 94 QSPSPHELQVLSPLSPLSPEP--PGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQ 151 + P+P + +P + P P P P P+ L P + + P T + +D PA Sbjct: 771 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP---------TSTTSDKPA-- 819 Query: 152 EKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSP-SWEDGAAL 210 P P+ PT P P AP +P +PAPT P P S VS+P + ++ + Sbjct: 820 --PTTPKETAPTTPKEP-AP-------TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 869 Query: 211 QPPPAEAL----------LLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQ 260 P E+ L + P PG +P P ++TTT K + L+ Sbjct: 870 HKSPDESTPELSAEPTPKALENSPKEPG---VPTT-KTPAATKPEMTTTAKDKTTERDLR 925 Query: 261 ---RAESLQEKSIKE-AKTKCRTIASLLTA 286 + K KE A T +T S +TA Sbjct: 926 TTPETTTAAPKMTKETATTTEKTTESKITA 955 Score = 44.7 bits (104), Expect = 4e-04 Identities = 48/193 (24%), Positives = 68/193 (35%), Gaps = 26/193 (13%) Query: 105 SPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTR 164 +P +P P P P P P + P + T + T+ P P+ PT Sbjct: 389 APTTPKEPAPTTTKEPAPTTP---KEPAPT------TTKEPAPTTTKSAPTTPKEPAPTT 439 Query: 165 PTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQP----PPAEALLL 220 P P AP +P EPAPT P P+ + +P+ ++ A P P A Sbjct: 440 PKKP-APT-------TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491 Query: 221 PHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQE---KSIKEAKTKC 277 P P P P P P E TT + A + +E + K A T Sbjct: 492 PTTPKEPAP--TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 549 Query: 278 RTIASLLTAAPNP 290 + + T P P Sbjct: 550 KEPSPTTTKEPAP 562 Score = 42.7 bits (99), Expect = 0.002 Identities = 41/172 (23%), Positives = 60/172 (34%), Gaps = 11/172 (6%) Query: 83 TVQRLADEGPVQSPSPHELQVLSPLSP-----LSPEPPGAPVPQPLQPGSLRSPPDSEAY 137 T ++LA P + P+P + L+P +P +PE P P+ P + + P + Sbjct: 628 TPEKLAPTTP-EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 686 Query: 138 YGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDS 197 + + T K P T PT P +P E APT P+ Sbjct: 687 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 746 Query: 198 RVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTT 249 +P+ G A P A P P P G P + E TT Sbjct: 747 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAPTTLKEPAPTT 793 Score = 30.8 bits (68), Expect = 6.5 Identities = 78/395 (19%), Positives = 116/395 (29%), Gaps = 31/395 (7%) Query: 558 PVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVP 617 P +P + + P PPS A+ T ++ S + + E S E + S Sbjct: 110 PTSPPSSKKAP-PPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 168 Query: 618 AARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDAL 677 ++ + R+ + K N + L + N + + P D Sbjct: 169 SSSSSSSSSTIRK------IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEA 222 Query: 678 SLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP-PPVAPKPPSRGLLD 736 G + +F V T H T P + T P+ P+ PP + L Sbjct: 223 GSGLDNGDFK--VTTPDTSTTQHNKVSTSPKIT--TAKPINPRPSLPPNSDTSKETSLTV 278 Query: 737 GLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS-PSPTPSL 795 + + G E K S + +E T L P + PTP Sbjct: 279 NKETTVETKETTTTNKQTSTDGKE---KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKA 335 Query: 796 PPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPY 855 + K P + P P P P TPK+ P Sbjct: 336 ETTTK-GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP-TTPKEPA---------PT 384 Query: 856 QLKTAMFCFDEVPPT----PGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRA 911 K+A E PT P P P +E +T + T + APT A Sbjct: 385 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444 Query: 912 ATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASP 946 TT EP T P P P +P Sbjct: 445 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 94.4 bits (233), Expect = 5e-19 Identities = 145/551 (26%), Positives = 191/551 (34%), Gaps = 117/551 (21%) Query: 411 AAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASP---RPFQPGGGAPTPAPSIFNRS 467 A L G+Q P+ ++ E L P P +P++ P P P A +P Sbjct: 416 AKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELP 475 Query: 468 ARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPS 527 A P L RP S PL+P L +PPP S +PL P Sbjct: 476 ASPLPEALHLSRPLEES----PLSPPPEESPL-----SPPP--ESSPFSPLEESPLSPPE 524 Query: 528 HAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAP 587 +P S + TP S P S L P P++P P +PP A+ LS P Sbjct: 525 ESPPSPALETPLS--PPPEASPLSPPFEESPLSPPPEELPTSPPPEASR-------LSPP 575 Query: 588 LRPSARPEAPAPGPGAPEPPSAR------EQRISVPAARTGIL--QEARRRG--TRKQMF 637 S P P +P P ++R E +S P + + EA R Sbjct: 576 PEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPM 635 Query: 638 RPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKT 697 P EE+ SP PE V L P PEE LS Sbjct: 636 SPPPEESPMSPPPE----VSRLSPLPVVSRLSPPPEESPLS------------------P 673 Query: 698 LPHVTPKTPPPMAPKTPPPM--TPKTPPP--VAPKPPSRGLLDGLVNGAASSAGIPEPPR 753 P +P +PPP A + PP +P +PPP PP L L + +PE P+ Sbjct: 674 PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQ 733 Query: 754 LQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSP--SPTPSLPPSWKYSPNIRAP--P 809 L R + GP L PRP P SP P P SP P Sbjct: 734 LCPR-------------------SEGPHLSPRPEEPHLSPRPEEP---HLSPQAEEPHLS 771 Query: 810 PIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 869 P P L P+ P Q++GP +P QP +L + P Sbjct: 772 PQPEEPCLCA-VPEEPHLSP--QAEGPHLSP------------QPEELHLS-------PQ 809 Query: 870 TPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPV 929 T P S P+ + +PQP L+P P + +E EL P+ Sbjct: 810 TEEPHLSPVPEEPCL---------SPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPL 860 Query: 930 -PSPAPPPEAP 939 P P PPE P Sbjct: 861 SPRPEKPPEEP 871 Score = 88.6 bits (218), Expect = 3e-17 Identities = 145/598 (24%), Positives = 205/598 (34%), Gaps = 126/598 (21%) Query: 422 PPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNR--SARPFTPGLQG-- 477 PP A P LP SPLP + RP + +P P S + + PF+P + Sbjct: 461 PPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPL 520 Query: 478 ---QRPTTTSVIFRPLAPKRANDSLGGLSP-------APPPFLSSQGPTPLPSFTSGVPS 527 + + + PL+P LSP +PPP P P S S P Sbjct: 521 SPPEESPPSPALETPLSPP---PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577 Query: 528 HAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAP 587 +P+S P S P A S L+ P P++P P +PP A+ LS P Sbjct: 578 ESPMSPPPEESPMSPPPEA-SRLFPPFEESPLSPPPEESPLSPPPEASR-------LSPP 629 Query: 588 LRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNS 647 S P P +P P +R + V + + +E+ P EE+ S Sbjct: 630 PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP--------LSPPPEESPTS 681 Query: 648 PNPELLSLVQNLDEKPRAGGAESGP-----EEDALSLGAEACNFMQ-----PVGARSYKT 697 P PE L ++ P + E P E+ +SL E + + RS Sbjct: 682 PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG- 740 Query: 698 LPHVTPKTPPPMAPKTP--PPMTPKTPPP-VAPKPPSRGLLDGLVNGAASSAGIPEPPRL 754 PH++P+ P P P ++P+ P ++P+P L +PE P L Sbjct: 741 -PHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCL-----------CAVPEEPHL 788 Query: 755 --QGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSP--SPTPS---------------L 795 Q G L + + + ++ T P L P P P SP P Sbjct: 789 SPQAEGPHLSPQPE---ELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPR 845 Query: 796 PPSWKYSPNIRAPP--PIAYNPLLSPFFPQAARTLPKAQSQG-PRATPKQGIKALDFMRH 852 P SP + PP P P P A LP G P +P G AL Sbjct: 846 PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905 Query: 853 QPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLA---- 908 P +E+P +P S SP+ P P PL+P + A Sbjct: 906 PPLSPLP-----EELPLSPSGEPSLSPQLM-----------PPDPLPPPLSPIITAAAPP 949 Query: 909 ----------------------PRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGA 944 P AA L+ PI A+ P P PP P G+ Sbjct: 950 ALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007 Score = 86.7 bits (213), Expect = 1e-16 Identities = 131/551 (23%), Positives = 190/551 (34%), Gaps = 82/551 (14%) Query: 419 LQSPPRAQ--SAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQ 476 L PP A S P E + L P P P + P P +P P +P Sbjct: 536 LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP--- 592 Query: 477 GQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPS 536 P S +F P + +PPP S P P S S P +P+S P Sbjct: 593 ---PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPE 649 Query: 537 TPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEA 596 R S P+ S L P P++P P +PP A+ LS P P P + Sbjct: 650 VSRLS-PLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR-------LSPP--PEDSPTS 699 Query: 597 PAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLV 656 P P +P P + +S+P + +L P EE + P E Sbjct: 700 PPP-EDSPASPPPEDSLMSLPLEESPLL--------------PLPEEPQLCPRSE----G 740 Query: 657 QNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTP-- 714 +L +P PEE LS AE PH++P+ P P Sbjct: 741 PHLSPRPEEPHLSPRPEEPHLSPQAEE---------------PHLSPQPEEPCLCAVPEE 785 Query: 715 PPMTPKTP-PPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSR----- 768 P ++P+ P ++P+P L S +PE P L + E QS Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP--VPEEPCLSPQPEESHLSPQSEEPCLS 843 Query: 769 ---ADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAA 825 + ++ P L PRP P P P+ + P PPP P LSP + A Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF--PPP--GEPSLSPLLGEPA 899 Query: 826 RTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPI--ASGSPKTAR 883 + P P P++ L L + D +PP PI A+ P + Sbjct: 900 LSEPGEPPLSP--LPEE----LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSP 953 Query: 884 VQEIR-----RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEA 938 + E+ + + P A P+ T ++P +P + P P P + Sbjct: 954 LGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPAS 1013 Query: 939 PRGLGASPSSC 949 P + P C Sbjct: 1014 PILMEPLPPQC 1024 Score = 85.1 bits (209), Expect = 3e-16 Identities = 144/564 (25%), Positives = 190/564 (33%), Gaps = 94/564 (16%) Query: 421 SPPRAQSA---PPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG 477 SPP +S PPEA+ L P P +P++ P P +P P + S P L Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPP----PEESPMSPPPEVSRLSPLPVVSRLSP 664 Query: 478 QRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPST 537 P S PL+P +PPP S P P S TS P +P S P Sbjct: 665 --PPEES----PLSPPPEESPT-----SPPPEASRLSPPPEDSPTSPPPEDSPASPPPED 713 Query: 538 PRSSGPVTATSSLYIPAPS-------------RPVTPGGAPEPPAP---PSAA----AMT 577 S P+ + L +P RP P +P P P P A + Sbjct: 714 SLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ 773 Query: 578 STASIFLSAPLRPSARPEAPAPGPGAPEP------PSAREQRISVPAARTGILQEARRRG 631 + P P P+A P +P+P P E +S P L Sbjct: 774 PEEPCLCAVPEEPHLSPQAEGPHL-SPQPEELHLSPQTEEPHLS-PVPEEPCLSPQ---- 827 Query: 632 TRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVG 691 + P EE SP PE L L++ P + E PEE E P G Sbjct: 828 PEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPG 887 Query: 692 ARSYKTL---PHVT-PKTPP--------PMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLV 739 S L P ++ P PP P++P P ++P+ PP PP ++ Sbjct: 888 EPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAA 947 Query: 740 NGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSW 799 A S G E P G G+ + A +P P P P LPPS Sbjct: 948 PPALSPLGELEYPF--GAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPS- 1004 Query: 800 KYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKT 859 SP + PI PL P +L S + +P AL Sbjct: 1005 PGSP-VGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP----ALPL---------- 1049 Query: 860 AMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPI 919 VP PI K V + + +EP P L P A + L P+ Sbjct: 1050 ------SVPSPLSPIG----KVVGVSDEAELHEMETEKVSEPECPA-LEPSATSPLPSPM 1098 Query: 920 WRTELASAPVPSPAPPPEAPRGLG 943 S P PSPAP + GLG Sbjct: 1099 GDL---SCPAPSPAPALDDFSGLG 1119 Score = 77.8 bits (190), Expect = 5e-14 Identities = 197/844 (23%), Positives = 287/844 (34%), Gaps = 172/844 (20%) Query: 89 DEGPVQSPSPHELQVLSP-----LSPLSPEPPGAPVPQ------PLQPGSLRSPPDSEAY 137 +E P+ SP P E P LSP E P +P+P+ PL+ L PP+ Sbjct: 445 EESPL-SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503 Query: 138 YGETDSDADGPATQEKPRRPRRRGPTRP---TPPGAPPDEVYLS----DSPAEPAPT-IP 189 +S P +E P P P P TP PP+ LS +SP P P +P Sbjct: 504 SPPPESSPFSPL-EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP 562 Query: 190 GPPSQGDSRVSSPSWE-------DGAALQPPPAEALLLP---HGPLRPGPHLIPMVGPVP 239 P SR+S P E + + + PPP + L P PL P P P+ P Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS---P 619 Query: 240 HPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFK 299 P A L+ + ES + ++ + S L+ P + Sbjct: 620 PPEASRLSPPPEDSPMSPPPE--ESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEE 677 Query: 300 KRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDM 359 + + +S E+ PP +S SL + +SP L + Sbjct: 678 SPTSPPPEASRLS------PPPEDSPTSPPPEDSPASPPPEDSLMSLPLE---ESPLLPL 728 Query: 360 ELARAGSRASEGQGSGLGGQLSEVSGRGVQ-----------LFEQQRQRADSSTQELARV 408 SEG + +S R + L Q + + E + Sbjct: 729 PEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL 788 Query: 409 EPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPA-PVASPRPFQPGGGAPTPAPSIFNRS 467 P A G L P P+ SP+P P SP+P + + P + S Sbjct: 789 SPQA--EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCL---S 843 Query: 468 ARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTP--LPSFTS-G 524 RP L + PL+P+ P PP Q P P LP F G Sbjct: 844 PRPEESHLSPELEKP------PLSPR----------PEKPPEEPGQCPAPEELPLFPPPG 887 Query: 525 VPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSR-PVTPGGAP---------EPPAPPSAA 574 PS +P+ G P+ P + P P P++P G P +P PP + Sbjct: 888 EPSLSPLLGEPALSEPGEPPLS------PLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP 941 Query: 575 AMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRK 634 +T+ A LS P E P G +P E ++ P T I Sbjct: 942 IITAAAPPALS----PLGELEYPFGAKGDSDP----ESPLAAPILETPI----------- 982 Query: 635 QMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARS 694 P E P P ++ P + G+ GP L M+P+ + Sbjct: 983 ---SPPPEANCTDPEPVPPMIL------PPSPGSPVGPASPIL---------MEPLPPQC 1024 Query: 695 YKTLPH-VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLD--GLVNGAASSAGIPEP 751 L H + P+ PP + +PP + P P++P G+ D L PE Sbjct: 1025 SPLLQHSLVPQNSPP-SQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPEC 1083 Query: 752 PRLQGRG--------GELFAKRQSRA-----------DRYVVEGTPGPGLGPRPRSPSPT 792 P L+ G+L S A D ++G PG P P T Sbjct: 1084 PALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQP---EPGQT 1140 Query: 793 P-SLPPSWKYSPNIRAPPPIA-YNPLLSPFFPQAARTL----PKAQSQGPRA----TPKQ 842 P SL K SP + P +A P+ +P+ +T P + + PRA TP Sbjct: 1141 PGSLASELKGSPVLLDPEELAPVTPM--EVYPECKQTAGQGSPCEEQEEPRAPVAPTPPT 1198 Query: 843 GIKA 846 IK+ Sbjct: 1199 LIKS 1202 Score = 61.2 bits (147), Expect = 4e-09 Identities = 112/469 (23%), Positives = 150/469 (31%), Gaps = 109/469 (23%) Query: 423 PRAQSAPPEAAVLPPSPLPAPVASPRPF-----QPGGGAP----------------TPAP 461 PR +APP PP P P + P +PG G P TP P Sbjct: 2187 PRFPTAPP---TYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDP 2243 Query: 462 SIFNRS------ARPFTPGLQGQRPTTTSVIFRPLAPKRA-----NDSLGGLSPA-PPPF 509 + R A P +PG+ G + + + P R + LG SP+ PP Sbjct: 2244 FLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPN 2303 Query: 510 LSSQGPTPLPSFTSGVPSHAP-VSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPP 568 L + G+ P V +P TPR+S + L + P AP PP Sbjct: 2304 LGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPP 2363 Query: 569 APPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEAR 628 + P S + PL P RP+ P P PP + S P +R Sbjct: 2364 SHPDIFRPGSYTDPYAQPPLTP--RPQPPPPESCCALPPRSLP---SDPFSRV------- 2411 Query: 629 RRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQ 688 P ++++S L PR AE A F Sbjct: 2412 ----------PASPQSQSSSQSPL---------TPRPLSAE------AFCPSPVTPRFQS 2446 Query: 689 PVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGI 748 P P + PP P++ P P PP P+PP G + + AG Sbjct: 2447 P------------DPYSRPPSRPQSRDPFAPLHKPP-RPQPPEVAFKAGSLAHTSLGAGG 2493 Query: 749 PEPPRLQGRGGELFAKRQSRADRYVVE--------GTPGP-------GLG-PRPRSPSPT 792 G GEL AK S V GTP P +G P + P P Sbjct: 2494 FPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQ 2553 Query: 793 PSLPP------SWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQG 835 P LPP + P + P Y F P + P + S G Sbjct: 2554 PGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTG 2602 Score = 60.1 bits (144), Expect = 1e-08 Identities = 163/673 (24%), Positives = 231/673 (34%), Gaps = 122/673 (18%) Query: 122 PLQPGSLRSPPDSEA---YYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLS 178 P QPG+L SPP + A + G + A + + +P P P P E++L Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKP----PAGSVPGPDSPGELFLK 2162 Query: 179 DSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQP--PPAEALLLPHGPLRPGPHLIPMVG 236 P PA PSQ D +P++ L+P P A P+ P PM+G Sbjct: 2163 LPPQVPAQV----PSQ-DPFGLAPAYP----LEPRFPTAPPTYPPYPSPTGAPAQPPMLG 2213 Query: 237 PVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVL 296 P A +T + Q S + +K +C ++ +L P S GV Sbjct: 2214 ASSRPGAGQPGEFHTTPPGTPRHQ--PSTPDPFLKP---RCPSLDNLAV----PESPGV- 2263 Query: 297 MFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPY 356 G +E PP ES E + ++ S + P Sbjct: 2264 -------------------GGGKASEPLLSPPPFGESRKALEVKKEELGASSPS-YGPPN 2303 Query: 357 LDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNG 416 L G S G+ LGG ++L +A T ++VEP + G Sbjct: 2304 L-------GFVDSPSSGTHLGG---------LELKTPDVFKAPL-TPRASQVEPQSPGLG 2346 Query: 417 EGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGA-PTPAPSIFNRSARPFTPGL 475 Q PP AQ+ P+P + P F+PG P P P TP Sbjct: 2347 LRPQEPPPAQAL-----------APSPPSHPDIFRPGSYTDPYAQP--------PLTPRP 2387 Query: 476 QGQRPTTTSVIFRPLAPKRA--NDSLGGLSPAPPPFLSSQGP-TPLPSFTSGVPSHAPVS 532 Q P + + P R+ +D + +P SSQ P TP P S Sbjct: 2388 QPPPPESCCAL-----PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPL------SAEAFC 2436 Query: 533 GSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMT-STASIFLSAPLRPS 591 SP TPR P + P P P P P PP A S A L A P+ Sbjct: 2437 PSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPA 2496 Query: 592 ARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNS-PNP 650 A P PA A P + P + + R T Q G+ K P P Sbjct: 2497 ALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAV--GEPSLKPPVPQP 2554 Query: 651 ELLSLVQNLDEKPRAGGAESGPEEDALSLG-AEACNFMQPVGARSYKTLPHVTPKTPPPM 709 L P + GP +LG ++ N+ G P +P P Sbjct: 2555 GL--------PPPHGINSHFGP---GPTLGKPQSTNYTVATG----NFHPSGSPLGPSSG 2599 Query: 710 APKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRA 769 + ++P PP V P P G L L +GA+ +GI P + G + A Sbjct: 2600 STGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATA 2659 Query: 770 DRYVVEGTPGPGL 782 + + GT PG+ Sbjct: 2660 E---LPGTQDPGM 2669 Score = 56.2 bits (134), Expect = 1e-07 Identities = 137/553 (24%), Positives = 187/553 (33%), Gaps = 100/553 (18%) Query: 435 LPPSP----LPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSV--IFR 488 +PP P P P A+P F G+PT P+ + SA F G P S +F Sbjct: 2106 IPPQPGALGSPPPAAAPTIFI---GSPT-TPAGLSTSADGFLKPPAGSVPGPDSPGELFL 2161 Query: 489 PLAPKRA----NDSLGGLSPAPP--PFLSSQGPT--PLPSFTSGVPSHAPVSGSPSTPRS 540 L P+ + GL+PA P P + PT P PS T G P+ P+ G+ S P + Sbjct: 2162 KLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT-GAPAQPPMLGASSRPGA 2220 Query: 541 SGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPG 600 P + P P P+P P ++ + A PE+P G Sbjct: 2221 GQP----GEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAV------------PESPGVG 2264 Query: 601 PGAP-----EPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSL 655 G PP E R ++ + + + G F + EL + Sbjct: 2265 GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTP 2324 Query: 656 -VQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTP 714 V PRA E P+ L L + +P A++ P P P + P Sbjct: 2325 DVFKAPLTPRASQVE--PQSPGLGLRPQ-----EPPPAQALAPSPPSHPDIFRPGSYTDP 2377 Query: 715 PPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVV 774 P TP P P P S L + + +P P+ Q R A+ + Sbjct: 2378 YAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAF-- 2435 Query: 775 EGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQ 834 P P + PR +SP P S PPS P R P + PL P PQ KA S Sbjct: 2436 --CPSP-VTPRFQSPDPY-SRPPS---RPQSRDP----FAPLHKPPRPQPPEVAFKAGSL 2484 Query: 835 GPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPA 894 + G A A +VP P SP T TP+ Sbjct: 2485 AHTSLGAGGFPA-------ALPAGPAGELHAKVPSGQPPNFVRSPGTGAF-----VGTPS 2532 Query: 895 PQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGA---------S 945 P P A + EP + PVP P PP P G+ + Sbjct: 2533 PMRFTFPQA-----------VGEPSLK-----PPVPQPGLPP--PHGINSHFGPGPTLGK 2574 Query: 946 PSSCGFQVARPRF 958 P S + VA F Sbjct: 2575 PQSTNYTVATGNF 2587 Score = 54.3 bits (129), Expect = 5e-07 Identities = 183/815 (22%), Positives = 276/815 (33%), Gaps = 118/815 (14%) Query: 100 ELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPAT---QEKPRR 156 +LQ L L P +PG+ SP GP T QE Sbjct: 4221 QLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAG 4280 Query: 157 PRRRGPTR-PTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPA 215 PR +GP R P PPGA L P P+ P P + S++ SPS + Q PP Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKR-PSQLPSPSSQLPTEAQLPPT 4339 Query: 216 EALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKA--------KQAKLQRAE--SL 265 P P GP L P G V P A L T K A+ Q+ E SL Sbjct: 4340 H----PGTPKPQGPTLEPPPGRV-SPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSL 4394 Query: 266 QEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEED 325 + + + AS L+ P + + + +R E Sbjct: 4395 VPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREAN--------------GEPI 4440 Query: 326 GVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQL-SEVS 384 G P TS L S+A L Q + + + + R SEG + + G + S+++ Sbjct: 4441 GAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQL----STGRGSEGLRAEINGHIDSKLA 4496 Query: 385 GRGVQLFEQQRQRADSS-----TQELARVEPAA---------MLNGEGLQSPPRAQSAPP 430 G +L + D++ T + RV+ A+ + +G+++ Sbjct: 4497 GLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLK 4556 Query: 431 EAAVLPPSPLPAPVASPRPFQP-GGGAPTPAPS----IFNRSARPFTPGLQGQRPTTTSV 485 + L P PA A+ F P G G P S F A P P Q T ++ Sbjct: 4557 QELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNL 4616 Query: 486 IFRPLAPKRANDSLGGLSPAPPPFLSSQ---GPTPLPSFTSGVPSHAPVSGSPSTPRSSG 542 P P L P PPP + + G TP A S R + Sbjct: 4617 SNPPTPP-------SSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTS 4669 Query: 543 PVTATSSL-YIPAP----SRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAP 597 V + L +P P + V + +P S +S SI P P Sbjct: 4670 EVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESIL------GEEAPRFP 4723 Query: 598 APGPGAPEPPSAREQRI--SVPAARTGILQEARRRGTRKQMFRPGK------EETKNSPN 649 G G E + +P A + + + G + PGK E+ K S Sbjct: 4724 HLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGA-LGLEVPGKLPVTTWEKGKGSEV 4782 Query: 650 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 709 +L+ V K G + E ++ + + + P T P P Sbjct: 4783 SVMLT-VSAAAAKNLNGVMVAVAELLSMKI-PNSYEVLFPESPARAGTEPKKGEAEGPGG 4840 Query: 710 APKTPPPMTPKTPP-------PVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELF 762 K +P T P V P + LD +++ + PEPP + Sbjct: 4841 KEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLD-ILSLLKQESPAPEPPTQHS-----Y 4894 Query: 763 AKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAP-PPIAYNPLLSPF- 820 S D + P P P +P+P+ PP+ P + P P+A P+ SP Sbjct: 4895 TYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPT---EPLVELPTEPLAEPPVPSPLP 4951 Query: 821 ---FPQAARTLPKAQ-------SQGPRATPKQGIK 845 P++AR P+A+ S+ PR +G++ Sbjct: 4952 LASSPESARPKPRARPPEEGEDSRPPRLKKWKGVR 4986 Score = 53.9 bits (128), Expect = 7e-07 Identities = 54/195 (27%), Positives = 75/195 (38%), Gaps = 48/195 (24%) Query: 90 EGPVQSPSPHELQVLSPL--SPLSPEP---------------------PGAPVPQ----- 121 E +++P E+ +L P SPLSP P P +P+P+ Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLS 486 Query: 122 -PLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRP---TPPGAPPDEVYL 177 PL+ L PP+ +S P +E P P P P TP PP+ L Sbjct: 487 RPLEESPLSPPPEESPLSPPPESSPFSP-LEESPLSPPEESPPSPALETPLSPPPEASPL 545 Query: 178 S----DSPAEPAP-TIPGPPSQGDSRVSSPSWE-------DGAALQPPPAEALLLP---H 222 S +SP P P +P P SR+S P E + + + PPP + L P Sbjct: 546 SPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605 Query: 223 GPLRPGPHLIPMVGP 237 PL P P P+ P Sbjct: 606 SPLSPPPEESPLSPP 620 Score = 50.4 bits (119), Expect = 8e-06 Identities = 49/173 (28%), Positives = 64/173 (36%), Gaps = 25/173 (14%) Query: 82 LTVQRLADEGPVQSPS-------PHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDS 134 L + R +E P+ P P E SPL PP P P L PP++ Sbjct: 483 LHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA 542 Query: 135 EAYYGETDSDADGPATQEKPRRP-----RRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIP 189 + P +E P P R P +P PP+E SP P P Sbjct: 543 SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE-----SPMSPPPEAS 597 Query: 190 G--PPSQGDSRVSSPSWEDGAALQPPPAEALLLP---HGPLRPGPHLIPMVGP 237 PP + +S +S P E + L PPP + L P P+ P P PM P Sbjct: 598 RLFPPFE-ESPLSPPPEE--SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647 Score = 50.4 bits (119), Expect = 8e-06 Identities = 161/721 (22%), Positives = 247/721 (34%), Gaps = 135/721 (18%) Query: 90 EGPVQSPSPHELQVLSP-LSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGP 148 +GP + P+P P L P+ P PP + +P +P L SP + ++A P Sbjct: 4284 QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPS------SQLPTEAQLP 4337 Query: 149 ATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGA 208 T P P+ +GPT PPG +S + A+ A T+ S+G P D Sbjct: 4338 PTH--PGTPKPQGPTLEPPPGR------VSPAAAQLADTL---FSKGLGPWDPP---DNL 4383 Query: 209 ALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEK 268 A P ++ L+P HL + G V P A L+ + + L A+S++ + Sbjct: 4384 AETQKPEQSSLVP-------GHLDQVNGQVV-PEASQLSIKQEPREEPCAL-GAQSVKRE 4434 Query: 269 SIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVP 328 + E T LL A P + +L+ ++ RAK L + G G+E G+ Sbjct: 4435 ANGEPIGAPGTSNHLLLAGPRSEAGHLLL--QKLLRAKNVQL-----STGRGSE---GLR 4484 Query: 329 PTSESELDEE-AFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRG 387 +D + A + + S+ + L R + + + G Sbjct: 4485 AEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDG 4544 Query: 388 VQLFEQQRQRADSSTQELARVEPAAMLNGE-----GLQSPPRAQSAPPEA---AVLPPSP 439 V+ E ++ L EPA N G P QS A LP P Sbjct: 4545 VRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGP 4604 Query: 440 ------LPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQ-GQRPTTTSV------I 486 L S P P PTP PS+ + TP + G+ P + Sbjct: 4605 DYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERA 4664 Query: 487 FRPLAPKRANDSLGGLSPAPP----PFLSSQGPTPLPSFTSGVPSHAPVS---------- 532 R + ++ D L L P PP + + S S VP+ +P S Sbjct: 4665 LRDTSEVKSLDLLAAL-PTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFP 4723 Query: 533 --GS--------------PSTPRSSGPVTATSSLY----IPAPSR-PVT-----PGGAPE 566 GS P PR+S PV + Y + P + PVT G Sbjct: 4724 HLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVS 4783 Query: 567 PPAPPSAAAMTSTASIFLSAPLRPSAR---------PEAPA-----PGPGAPEPPSAREQ 612 SAAA + + ++ S + PE+PA P G E P +E+ Sbjct: 4784 VMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEK 4843 Query: 613 RISVPAARTGILQEARRRGTRKQMFRPG--KEETKNSPNPELLSLVQNLDEKPRAGGAES 670 + + TG P K+ P L S + L + A Sbjct: 4844 GLEGKSPDTG----------------PDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPE 4887 Query: 671 GPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPP 730 P + + + + Q + P +P P P +P T P + T P P P Sbjct: 4888 PPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVP 4947 Query: 731 S 731 S Sbjct: 4948 S 4948 Score = 42.4 bits (98), Expect = 0.002 Identities = 51/174 (29%), Positives = 64/174 (36%), Gaps = 32/174 (18%) Query: 91 GPVQSPSPHELQVLSPLSPLSP-----------EPPGAPVPQPLQPGS--LRSPPDSEAY 137 G + SP P + SP +P +PP VP P PG L+ PP A Sbjct: 2111 GALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQ 2170 Query: 138 YGETDSDADGPATQEKPRRPRR--RGPTRPTPPGAPPDEVYLSDS-------PAEPAPTI 188 D PA +PR P P P+P GAP L S P E T Sbjct: 2171 VPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTP 2230 Query: 189 PGPPSQGDSRVSSPSWEDGAALQP--PPAEALLLPHGP-LRPGPHLIPMVGPVP 239 PG P PS D L+P P + L +P P + G P++ P P Sbjct: 2231 PGTPRH------QPSTPD-PFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277 Score = 41.6 bits (96), Expect = 0.004 Identities = 130/597 (21%), Positives = 178/597 (29%), Gaps = 125/597 (20%) Query: 94 QSPSPHELQVLSPLSPLSPE-------------PPGAPVPQP--------LQPGSLRSPP 132 Q P P Q L+P P P+ PP P PQP L P SL S P Sbjct: 2350 QEPPP--AQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDP 2407 Query: 133 DSEAYYG-ETDSDADGPATQE---------KPRRPRRRGPTRPTPPGAPPDEVYLSDSPA 182 S ++ S + P T P PR + P + P + P S P Sbjct: 2408 FSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQ----SRDPF 2463 Query: 183 EPA--PTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPH 240 P P P PP S GA P LP GP +P G P+ Sbjct: 2464 APLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAA-----LPAGPAGELHAKVPS-GQPPN 2517 Query: 241 PVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKK 300 V T + + +++ E S+K + P PH G+ Sbjct: 2518 FVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQ--------PGLPPPH--GINSHFG 2567 Query: 301 RRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLT----NQSDWDSPY 356 K ++ A G + P+S S + S R + D PY Sbjct: 2568 PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPY 2627 Query: 357 LDMELARAGSRAS-----EGQGSGLGGQLSE----------VSGRGVQLFEQQRQRA--- 398 L ++ S E G+G+G L+ +SG E+QRQR Sbjct: 2628 LSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLR 2687 Query: 399 -----DSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAV------------------- 434 + R E G PP + A P + Sbjct: 2688 ELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSS 2747 Query: 435 ---LPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLA 491 LPPS L P+ P F P P A P + + ++ S F A Sbjct: 2748 LVGLPPSKLSGPILGPGSFPSDDRLSRPPP-----PATPSSMDVNSRQLVGGSQAFYQRA 2802 Query: 492 PKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSS-GPVTATSSL 550 P + L Q T S + + P + P R + G A S Sbjct: 2803 PYPGSLP---LQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGIST 2859 Query: 551 YIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPP 607 +P P PV P P P + + L P P PG G P+ P Sbjct: 2860 RLPGPGEPV-----PGPAGPAQFIELRHN----VQKGLGPGG---TPFPGQGPPQRP 2904 Score = 39.7 bits (91), Expect = 0.014 Identities = 106/461 (22%), Positives = 157/461 (34%), Gaps = 83/461 (18%) Query: 379 QLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAP----PEAAV 434 Q ++ + QL +QQ+Q+ Q+ + + + L SP + Q P Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPA 4003 Query: 435 LPPSPLPAPVA-SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPK 493 P +P A P G T P++ + + + G T+ P Sbjct: 4004 KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPG 4063 Query: 494 RANDSLGG------LSPAPPPFLSS---QGPTPLPS---------FTSGVPSHAPVSGSP 535 SL G + P P P SS Q P LP T+G SH + Sbjct: 4064 EVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGS 4123 Query: 536 STPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPE 595 S+ SS P L P+ S PG + P L P++ + P+ Sbjct: 4124 SSEASSVP----HLLAQPSVSLGDQPGSMTQNLLGPQQP--------MLERPMQNNTGPQ 4171 Query: 596 APAPGP---------GAPEPPSAREQRISV-------PAAR----------TGILQEARR 629 P PGP G P+ + R + P R +L + + Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231 Query: 630 RGTRKQMFRPGKEE--TKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM 687 + ++ P +E T+ SP LL L P G ++GP ++ LGA Sbjct: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFP---GPQTGPLQE---LGAGP---- 4281 Query: 688 QPVGARSYKTLPHVTPKTPPPMAP--KTPPPMTPKTP--PPVAPKPPSRGLLDGLVNGAA 743 +P G P T P + P TPPP +P+ P P P P S+ L A Sbjct: 4282 RPQGPPRLPAPPGAL-STGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQ-----LPTEAQ 4335 Query: 744 SSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGP 784 P P+ QG E R S A + + GLGP Sbjct: 4336 LPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGP 4376 Score = 37.7 bits (86), Expect = 0.053 Identities = 24/64 (37%), Positives = 33/64 (51%), Gaps = 5/64 (7%) Query: 886 EIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWR--TE-LASAPVPSPAPPPEAPRGL 942 ++R+ S P P+ + P P+ LAP A+ EP+ TE LA PVPSP P +P Sbjct: 4902 DVRQLSAPPPEEPSPP--PSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESA 4959 Query: 943 GASP 946 P Sbjct: 4960 RPKP 4963 Score = 36.6 bits (83), Expect = 0.12 Identities = 37/137 (27%), Positives = 45/137 (32%), Gaps = 29/137 (21%) Query: 86 RLADEGPVQSPS--PHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDS 143 +L + P Q PS P L PL P P P P P G+ PP G + Sbjct: 2162 KLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPP----MLGASSR 2217 Query: 144 DADGPATQEKPRRPRRRGPTRPTPPGAP------PDEVYLSDSPAEPAPTIPGPPSQGDS 197 G + G TPPG P PD P+ +P P G Sbjct: 2218 PGAG-----------QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG 2266 Query: 198 RVSSPSWEDGAALQPPP 214 + S P L PPP Sbjct: 2267 KASEP------LLSPPP 2277 Score = 35.4 bits (80), Expect = 0.26 Identities = 81/347 (23%), Positives = 106/347 (30%), Gaps = 48/347 (13%) Query: 359 MELARAGSRASEGQ-GSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAA----M 413 + L S GQ GSG + S V Q + S TQ L + M Sbjct: 4105 VSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPM 4164 Query: 414 LNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTP 473 N G Q PP+ LP + V R G A P + + Sbjct: 4165 QNNTGPQ-PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQ 4223 Query: 474 GLQGQRPTTTSVIFRPLAPKRA----NDSLGGLSPAPPPFLSSQGPT--PLPSFTSGVPS 527 L QR S R P + L GL P GP PL +G Sbjct: 4224 ALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRP 4283 Query: 528 HAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAP 587 P PR P A S+ + P P P +P+ P PS S+ Sbjct: 4284 QGP-------PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS-------- 4328 Query: 588 LRPSARPEAPAPGPGAP-------EPPSAREQRISVPAARTGILQE----------ARRR 630 + + P PG P EPP R + A T + A + Sbjct: 4329 -QLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQ 4387 Query: 631 GTRKQMFRPGKEETKNS---PNPELLSLVQNLDEKPRAGGAESGPEE 674 + PG + N P LS+ Q E+P A GA+S E Sbjct: 4388 KPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKRE 4434 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 94.4 bits (233), Expect = 5e-19 Identities = 208/879 (23%), Positives = 292/879 (33%), Gaps = 177/879 (20%) Query: 92 PVQSPSPHELQVLSPLSPLSPEPPGAPVPQP-LQP---GSLRSPPDSEAYYGETDSDADG 147 P +P+ + + P S + PPGAP P P L P G + S P G S G Sbjct: 187 PSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGG 246 Query: 148 P--ATQEKP-------------RRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPP 192 P Q P P + PT P G P ++ P P +P PP Sbjct: 247 PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFP-HVTPNLPPPP 305 Query: 193 SQGDSRVSSPSWEDGAALQPPPAEALLLPH------GPLRPGPHLIPMVGPVPHPV---- 242 + +S S G QP P L PH G L PGP P + P PH + Sbjct: 306 ALRPLNNASAS-PPGLGAQPLPGH-LPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPAS 363 Query: 243 ----AEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMF 298 A + Y+ + + + S S + + S + P P S V Sbjct: 364 SSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV--- 420 Query: 299 KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLD 358 + KYT S + A G PP R L N + P+ Sbjct: 421 ---SNQPPKYTQPSLPSQ----AVWSQGPPPPPPY---------GRLLANSNAHPGPFPP 464 Query: 359 MELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEG 418 A++ + Q + + Q +QQ+Q +S P + G Sbjct: 465 STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSS 524 Query: 419 LQSPPRAQSA--------PPEAAVLPP----------SPLPAPVAS-------------- 446 + P A S PP A LPP P PV+S Sbjct: 525 HHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP 584 Query: 447 ---PRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP-------KRAN 496 P P Q GAP P P + + T ++ ++ +P KRA Sbjct: 585 CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA- 643 Query: 497 DSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPS 556 S G A PP P PSF +G P + P+ P + P + T P P Sbjct: 644 PSPGAYKTATPPGYKPGSP---PSFRTGTPPGYRGTSPPAGPGTFKPGSPTVG---PGPL 697 Query: 557 RPVTPGGAPEPPAPPSAAAM--TSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRI 614 P P G P P PP+A A +A+ P PE+P P +P PP + + Sbjct: 698 PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPP---PKVV 754 Query: 615 SVP--AARTGILQEARRRG----TRKQMFRPGKEETK-NSPNPELLSLVQN------LDE 661 VP A+++ + RG R ++ E +K +L+ V+ +E Sbjct: 755 DVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREE 814 Query: 662 KPRAGGAESGPE---------EDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK 712 K R E E E ++ L E PV S +PH P P Sbjct: 815 KEREREREREKEREREKERELERSVKLAQEG---RAPVECPSLGPVPHRPPFEPGSAVAT 871 Query: 713 TPPPMTPKTPP---------PVAPKPPSR--------GLLDGLVNGAASSAGIPEPPRLQ 755 PP + P TP P P +R G +D + G A P + Sbjct: 872 VPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAR 931 Query: 756 GRGGELFAKRQSRADRY------------VVEGTPGPGLGPRPR------SPSPTPSLPP 797 R E A+ + DR + G PGPGL P PR P P P L P Sbjct: 932 ERERE--ARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGP-PGLHP 988 Query: 798 SWKYSPNI----RAPPPIAYNPLLSPFFPQAARTLPKAQ 832 + + P++ R +A P L P A R + Q Sbjct: 989 -FPFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQ 1026 Score = 68.6 bits (166), Expect = 3e-11 Identities = 169/738 (22%), Positives = 239/738 (32%), Gaps = 134/738 (18%) Query: 299 KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLD 358 +K RQ AKK + EE P ++ EE TN + Sbjct: 48 EKSRQTAKKARV------------EEASTPKVNKQGRSEEISESESEETNAPK--KTKTE 93 Query: 359 MELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEG 418 EL R S + S G L++ + +Q + S VE + + Sbjct: 94 QELPRPQSPSD--LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGL 151 Query: 419 LQSPPRAQSAPPEAAVLPPSPLPAPVASPRP----FQPGGGAPTPAPSIFNRSARPFTPG 474 Q P R PP + PPSP P P ++PR F+P P+ P+ ++ P T Sbjct: 152 SQGPARPYHPPP---LFPPSPQP-PDSTPRQPEASFEPH---PSVTPTGYHAPMEPPTSR 204 Query: 475 LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGS 534 + P P P+ GG+ PP G +G H P Sbjct: 205 MFQAPPGAP-----PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPP---- 255 Query: 535 PSTPRSSGPVTATSSLYIPAPSRPVTP-GGAPEPPAPPSAAAMTSTASIFLSAPLRPSAR 593 P+TP S V+++ + P P TP GG P APP A T ++ LRP Sbjct: 256 PTTPIS---VSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNN 312 Query: 594 PEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKN-SPNPEL 652 A PG GA P G L G PG E+ +P+P Sbjct: 313 ASASPPGLGAQPLP--------------GHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358 Query: 653 LSLVQNLDEKPRAG---GAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 709 L + P + S A S + + + P A + LP PPP Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPAS--QALPSYPHSFPPPT 416 Query: 710 A---PKTPPPMTPKTPPPVA------PKPPSRGLLDGLVN----------GAASSAGIP- 749 + PP T + P A P PP G L N GA S+A P Sbjct: 417 SLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPV 476 Query: 750 -----EPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGP-------------------- 784 + Q + + ++Q + + G P PG P Sbjct: 477 STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSL 536 Query: 785 ---RPRSPSPTPSLPPSWKYSPNIRAP--PPIAYNPLLSPFFPQAARTLPK-AQSQGPRA 838 RP P P PP + S + P PP++ + S Q + + SQGP+ Sbjct: 537 GSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQG 596 Query: 839 TPKQG-------------IKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQ 885 P + + P KTA PP P P +P + Sbjct: 597 APYPFPPVPTVTTSSATLSTVIATVASSPAGYKTAS------PPGPPPYGKRAPSPGAYK 650 Query: 886 EIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP-PPEAPRGLGA 944 + P +P + P T P T T +P P P PP P GL + Sbjct: 651 TA---TPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPS 707 Query: 945 SPSSCGFQVARPRFSATR 962 P + P SAT+ Sbjct: 708 LPPPPAAPASGPPLSATQ 725 Score = 67.0 bits (162), Expect = 8e-11 Identities = 157/678 (23%), Positives = 209/678 (30%), Gaps = 127/678 (18%) Query: 108 SPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTR--P 165 S LS P P PL P S + PPDS E + T P +R Sbjct: 149 SGLSQGPARPYHPPPLFPPSPQ-PPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQ 207 Query: 166 TPPGAPPDEVYLSDSPAEPAPTIPGPP--SQGDSRVSSPSWEDGAALQPPPAEALLLPHG 223 PPGAPP L P + GPP +G SS +G PPP + + Sbjct: 208 APPGAPPPHPQL--YPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSS 265 Query: 224 PLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASL 283 P P PV L +L+ + A L Sbjct: 266 GASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPL 325 Query: 284 LTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDA 343 P+PH+ G M K TL A +PP S S Sbjct: 326 PGHLPSPHAMGQGMGGLPPGPEKGPTL----------APSPHSLPPASSSAPAPPMRFPY 375 Query: 344 RSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQ 403 S ++ S A A S +S S S+ F S Q Sbjct: 376 SSSSSSS-----------AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS-LSVSNQ 423 Query: 404 ELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPA-PS 462 +P+ Q PP PP +L S A P PF P GA + A P Sbjct: 424 PPKYTQPSLPSQAVWSQGPP---PPPPYGRLLANSN-----AHPGPFPPSTGAQSTAHPP 475 Query: 463 IFNRSARPFTPGLQGQR----------------PTTTSVIFRPLA--------PKRANDS 498 + Q Q+ P PL P + S Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS 535 Query: 499 LGGLSPAPPPFLSSQGPTPLP------SFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 552 LG L P PP GP LP S++ P+ PVS S ++ S T+ S Sbjct: 536 LGSLRPYPP------GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSS----TSQGSYPC 585 Query: 553 PAPSRPVTPGGAPE--PPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAR 610 PS P GAP PP P + + +++ + P+ A PGP PP + Sbjct: 586 SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP----PPYGK 641 Query: 611 EQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAES 670 A G + A G ++PG + + P P AG Sbjct: 642 R------APSPGAYKTATPPG-----YKPGSPPSFRTGTPP-----GYRGTSPPAGPGTF 685 Query: 671 GPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPM------------- 717 P + G + P G +LP PPP AP + PP+ Sbjct: 686 KPGSPTVGPGP-----LPPAGPSGLPSLP------PPPAAPASGPPLSATQIKQEPAEEY 734 Query: 718 -TPKTPPPVA--PKPPSR 732 TP++P P A P PP + Sbjct: 735 ETPESPVPPARSPSPPPK 752 Score = 50.4 bits (119), Expect = 8e-06 Identities = 49/182 (26%), Positives = 69/182 (37%), Gaps = 29/182 (15%) Query: 89 DEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGP 148 ++GP +PSPH L P S P P+ P S S S + + S + P Sbjct: 347 EKGPTLAPSPHS------LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400 Query: 149 ATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGA 208 A+Q P P PP + +S+ P P T P PSQ W G Sbjct: 401 ASQALPSYPH---------SFPPPTSLSVSNQP--PKYTQPSLPSQA-------VWSQGP 442 Query: 209 ALQPPPAEALLLPHGPLRPGPHLIPMVG--PVPHPVAEDLTTTYTQKAKQAKLQRAESLQ 266 PPP LL + PGP P G HP + Q+ +Q + Q+ + Q Sbjct: 443 --PPPPPYGRLLANSNAHPGP-FPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499 Query: 267 EK 268 ++ Sbjct: 500 QQ 501 Score = 32.7 bits (73), Expect = 1.7 Identities = 33/139 (23%), Positives = 51/139 (36%), Gaps = 15/139 (10%) Query: 96 PSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPA-TQEKP 154 P P L L S G+ P+ + + RS S G ++D+D + + P Sbjct: 97 PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDN-RSTSPSIYSPGSVENDSDSSSGLSQGP 155 Query: 155 RRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPP 214 RP P P P P ++ EP P++ +P+ A ++PP Sbjct: 156 ARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSV------------TPTGYH-APMEPPT 202 Query: 215 AEALLLPHGPLRPGPHLIP 233 + P G P P L P Sbjct: 203 SRMFQAPPGAPPPHPQLYP 221 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 94.4 bits (233), Expect = 5e-19 Identities = 208/879 (23%), Positives = 292/879 (33%), Gaps = 177/879 (20%) Query: 92 PVQSPSPHELQVLSPLSPLSPEPPGAPVPQP-LQP---GSLRSPPDSEAYYGETDSDADG 147 P +P+ + + P S + PPGAP P P L P G + S P G S G Sbjct: 187 PSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGG 246 Query: 148 P--ATQEKP-------------RRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPP 192 P Q P P + PT P G P ++ P P +P PP Sbjct: 247 PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFP-HVTPNLPPPP 305 Query: 193 SQGDSRVSSPSWEDGAALQPPPAEALLLPH------GPLRPGPHLIPMVGPVPHPV---- 242 + +S S G QP P L PH G L PGP P + P PH + Sbjct: 306 ALRPLNNASAS-PPGLGAQPLPGH-LPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPAS 363 Query: 243 ----AEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMF 298 A + Y+ + + + S S + + S + P P S V Sbjct: 364 SSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV--- 420 Query: 299 KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLD 358 + KYT S + A G PP R L N + P+ Sbjct: 421 ---SNQPPKYTQPSLPSQ----AVWSQGPPPPPPY---------GRLLANSNAHPGPFPP 464 Query: 359 MELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEG 418 A++ + Q + + Q +QQ+Q +S P + G Sbjct: 465 STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSS 524 Query: 419 LQSPPRAQSA--------PPEAAVLPP----------SPLPAPVAS-------------- 446 + P A S PP A LPP P PV+S Sbjct: 525 HHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP 584 Query: 447 ---PRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP-------KRAN 496 P P Q GAP P P + + T ++ ++ +P KRA Sbjct: 585 CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA- 643 Query: 497 DSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPS 556 S G A PP P PSF +G P + P+ P + P + T P P Sbjct: 644 PSPGAYKTATPPGYKPGSP---PSFRTGTPPGYRGTSPPAGPGTFKPGSPTVG---PGPL 697 Query: 557 RPVTPGGAPEPPAPPSAAAM--TSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRI 614 P P G P P PP+A A +A+ P PE+P P +P PP + + Sbjct: 698 PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPP---PKVV 754 Query: 615 SVP--AARTGILQEARRRG----TRKQMFRPGKEETK-NSPNPELLSLVQN------LDE 661 VP A+++ + RG R ++ E +K +L+ V+ +E Sbjct: 755 DVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREE 814 Query: 662 KPRAGGAESGPE---------EDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK 712 K R E E E ++ L E PV S +PH P P Sbjct: 815 KEREREREREKEREREKERELERSVKLAQEG---RAPVECPSLGPVPHRPPFEPGSAVAT 871 Query: 713 TPPPMTPKTPP---------PVAPKPPSR--------GLLDGLVNGAASSAGIPEPPRLQ 755 PP + P TP P P +R G +D + G A P + Sbjct: 872 VPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAR 931 Query: 756 GRGGELFAKRQSRADRY------------VVEGTPGPGLGPRPR------SPSPTPSLPP 797 R E A+ + DR + G PGPGL P PR P P P L P Sbjct: 932 ERERE--ARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGP-PGLHP 988 Query: 798 SWKYSPNI----RAPPPIAYNPLLSPFFPQAARTLPKAQ 832 + + P++ R +A P L P A R + Q Sbjct: 989 -FPFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQ 1026 Score = 68.6 bits (166), Expect = 3e-11 Identities = 169/738 (22%), Positives = 239/738 (32%), Gaps = 134/738 (18%) Query: 299 KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLD 358 +K RQ AKK + EE P ++ EE TN + Sbjct: 48 EKSRQTAKKARV------------EEASTPKVNKQGRSEEISESESEETNAPK--KTKTE 93 Query: 359 MELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEG 418 EL R S + S G L++ + +Q + S VE + + Sbjct: 94 QELPRPQSPSD--LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGL 151 Query: 419 LQSPPRAQSAPPEAAVLPPSPLPAPVASPRP----FQPGGGAPTPAPSIFNRSARPFTPG 474 Q P R PP + PPSP P P ++PR F+P P+ P+ ++ P T Sbjct: 152 SQGPARPYHPPP---LFPPSPQP-PDSTPRQPEASFEPH---PSVTPTGYHAPMEPPTSR 204 Query: 475 LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGS 534 + P P P+ GG+ PP G +G H P Sbjct: 205 MFQAPPGAP-----PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPP---- 255 Query: 535 PSTPRSSGPVTATSSLYIPAPSRPVTP-GGAPEPPAPPSAAAMTSTASIFLSAPLRPSAR 593 P+TP S V+++ + P P TP GG P APP A T ++ LRP Sbjct: 256 PTTPIS---VSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNN 312 Query: 594 PEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKN-SPNPEL 652 A PG GA P G L G PG E+ +P+P Sbjct: 313 ASASPPGLGAQPLP--------------GHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358 Query: 653 LSLVQNLDEKPRAG---GAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 709 L + P + S A S + + + P A + LP PPP Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPAS--QALPSYPHSFPPPT 416 Query: 710 A---PKTPPPMTPKTPPPVA------PKPPSRGLLDGLVN----------GAASSAGIP- 749 + PP T + P A P PP G L N GA S+A P Sbjct: 417 SLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPV 476 Query: 750 -----EPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGP-------------------- 784 + Q + + ++Q + + G P PG P Sbjct: 477 STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSL 536 Query: 785 ---RPRSPSPTPSLPPSWKYSPNIRAP--PPIAYNPLLSPFFPQAARTLPK-AQSQGPRA 838 RP P P PP + S + P PP++ + S Q + + SQGP+ Sbjct: 537 GSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQG 596 Query: 839 TPKQG-------------IKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQ 885 P + + P KTA PP P P +P + Sbjct: 597 APYPFPPVPTVTTSSATLSTVIATVASSPAGYKTAS------PPGPPPYGKRAPSPGAYK 650 Query: 886 EIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP-PPEAPRGLGA 944 + P +P + P T P T T +P P P PP P GL + Sbjct: 651 TA---TPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPS 707 Query: 945 SPSSCGFQVARPRFSATR 962 P + P SAT+ Sbjct: 708 LPPPPAAPASGPPLSATQ 725 Score = 67.0 bits (162), Expect = 8e-11 Identities = 157/678 (23%), Positives = 209/678 (30%), Gaps = 127/678 (18%) Query: 108 SPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTR--P 165 S LS P P PL P S + PPDS E + T P +R Sbjct: 149 SGLSQGPARPYHPPPLFPPSPQ-PPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQ 207 Query: 166 TPPGAPPDEVYLSDSPAEPAPTIPGPP--SQGDSRVSSPSWEDGAALQPPPAEALLLPHG 223 PPGAPP L P + GPP +G SS +G PPP + + Sbjct: 208 APPGAPPPHPQL--YPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSS 265 Query: 224 PLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASL 283 P P PV L +L+ + A L Sbjct: 266 GASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPL 325 Query: 284 LTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDA 343 P+PH+ G M K TL A +PP S S Sbjct: 326 PGHLPSPHAMGQGMGGLPPGPEKGPTL----------APSPHSLPPASSSAPAPPMRFPY 375 Query: 344 RSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQ 403 S ++ S A A S +S S S+ F S Q Sbjct: 376 SSSSSSS-----------AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS-LSVSNQ 423 Query: 404 ELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPA-PS 462 +P+ Q PP PP +L S A P PF P GA + A P Sbjct: 424 PPKYTQPSLPSQAVWSQGPP---PPPPYGRLLANSN-----AHPGPFPPSTGAQSTAHPP 475 Query: 463 IFNRSARPFTPGLQGQR----------------PTTTSVIFRPLA--------PKRANDS 498 + Q Q+ P PL P + S Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS 535 Query: 499 LGGLSPAPPPFLSSQGPTPLP------SFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 552 LG L P PP GP LP S++ P+ PVS S ++ S T+ S Sbjct: 536 LGSLRPYPP------GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSS----TSQGSYPC 585 Query: 553 PAPSRPVTPGGAPE--PPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAR 610 PS P GAP PP P + + +++ + P+ A PGP PP + Sbjct: 586 SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP----PPYGK 641 Query: 611 EQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAES 670 A G + A G ++PG + + P P AG Sbjct: 642 R------APSPGAYKTATPPG-----YKPGSPPSFRTGTPP-----GYRGTSPPAGPGTF 685 Query: 671 GPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPM------------- 717 P + G + P G +LP PPP AP + PP+ Sbjct: 686 KPGSPTVGPGP-----LPPAGPSGLPSLP------PPPAAPASGPPLSATQIKQEPAEEY 734 Query: 718 -TPKTPPPVA--PKPPSR 732 TP++P P A P PP + Sbjct: 735 ETPESPVPPARSPSPPPK 752 Score = 50.4 bits (119), Expect = 8e-06 Identities = 49/182 (26%), Positives = 69/182 (37%), Gaps = 29/182 (15%) Query: 89 DEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGP 148 ++GP +PSPH L P S P P+ P S S S + + S + P Sbjct: 347 EKGPTLAPSPHS------LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400 Query: 149 ATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGA 208 A+Q P P PP + +S+ P P T P PSQ W G Sbjct: 401 ASQALPSYPH---------SFPPPTSLSVSNQP--PKYTQPSLPSQA-------VWSQGP 442 Query: 209 ALQPPPAEALLLPHGPLRPGPHLIPMVG--PVPHPVAEDLTTTYTQKAKQAKLQRAESLQ 266 PPP LL + PGP P G HP + Q+ +Q + Q+ + Q Sbjct: 443 --PPPPPYGRLLANSNAHPGP-FPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499 Query: 267 EK 268 ++ Sbjct: 500 QQ 501 Score = 32.7 bits (73), Expect = 1.7 Identities = 33/139 (23%), Positives = 51/139 (36%), Gaps = 15/139 (10%) Query: 96 PSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPA-TQEKP 154 P P L L S G+ P+ + + RS S G ++D+D + + P Sbjct: 97 PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDN-RSTSPSIYSPGSVENDSDSSSGLSQGP 155 Query: 155 RRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPP 214 RP P P P P ++ EP P++ +P+ A ++PP Sbjct: 156 ARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSV------------TPTGYH-APMEPPT 202 Query: 215 AEALLLPHGPLRPGPHLIP 233 + P G P P L P Sbjct: 203 SRMFQAPPGAPPPHPQLYP 221 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 92.4 bits (228), Expect = 2e-18 Identities = 120/431 (27%), Positives = 142/431 (32%), Gaps = 71/431 (16%) Query: 409 EPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSA 468 +P + E L PP P A + PP PLP P P PG G P P P +A Sbjct: 898 QPPPLQGTEMLPPPPPPL---PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPP--LPGAA 952 Query: 469 RPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSH 528 P P L G + P P G P PPP + P P P +G+P Sbjct: 953 IPPPPPLPG-----AGIPLPPPLP-------GAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1000 Query: 529 APVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPL 588 P+ G+ P P IP P P+ G P PP P A P Sbjct: 1001 PPLPGAGIPPPPPLPGAG-----IPPPP-PLPGAGIPPPPPLPGAG--------IPPPPP 1046 Query: 589 RPSA--RPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKN 646 P A P P PG G P PP I P G G PG Sbjct: 1047 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-------AGIPPPPPLPGAGIPPP 1099 Query: 647 SPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTP 706 P P + + P GA P G + G LP V P Sbjct: 1100 PPLPGV-----GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154 Query: 707 PPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGL-VNGAASSAGIPEPPRLQGRGGELFAKR 765 PP+ PP P + P PP G+ G+ GIP PP L G G Sbjct: 1155 PPLPGAGIPPPPPLPGAGIPPPPPLPGV--GIPPPPPLPGVGIPPPPPLPGAG------- 1205 Query: 766 QSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQ-A 824 + P PG+G P+P P LPP P PPP P PQ Sbjct: 1206 -------IPPPPPLPGMG---IPPAPAPPLPP-----PGTGIPPPPLLPVSGPPLLPQVG 1250 Query: 825 ARTLPKAQSQG 835 + TLP Q G Sbjct: 1251 SSTLPTPQVCG 1261 Score = 80.9 bits (198), Expect = 5e-15 Identities = 137/514 (26%), Positives = 164/514 (31%), Gaps = 106/514 (20%) Query: 437 PSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRAN 496 PSP P P PG G P P P PG+ +T++ P P Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPP--------PPLPGMTVPTLPSTAI---PQPP---- 900 Query: 497 DSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPS 556 L G PPP P PLP +G+P P+ G+ P P IP P Sbjct: 901 -PLQGTEMLPPP------PPPLPG--AGIPPPPPLPGAGILPLPPLPGAG-----IPPP- 945 Query: 557 RPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSA--RPEAPAPGPGAPEPPSAREQRI 614 P PG A PP P A I L PL P A P P PG G P PP I Sbjct: 946 -PPLPGAAIPPPPP------LPGAGIPLPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGI 997 Query: 615 SVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEE 674 P G G PG P P + P GA P Sbjct: 998 PPPPPLPG-------AGIPPPPPLPGAGIPPPPPLPG-----AGIPPPPPLPGAGIPPPP 1045 Query: 675 DALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGL 734 G + G LP PPP+ PP P + P PP G+ Sbjct: 1046 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1105 Query: 735 LDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPS 794 GIP PP L G G + P PG G P P P Sbjct: 1106 ------------GIPPPPPLPGAG--------------IPPPPPLPGAGIPPPPPLPGAG 1139 Query: 795 LPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQP 854 +PP P + PPP PL P LP A P P GI P Sbjct: 1140 IPPP-PPLPRVGIPPP---PPLPGAGIPPPP-PLPGAGIPPPPPLPGVGIP-------PP 1187 Query: 855 YQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAP--TVLAPRAA 912 L +PP P +G P + + PAP PL P T + P Sbjct: 1188 PPLPGV-----GIPPPPPLPGAGIPPPPPLPGMGIPPAPAP-----PLPPPGTGIPPPPL 1237 Query: 913 TTLDEPIWRTELASAPVPSPAP----PPEAPRGL 942 + P ++ S+ +P+P PP P GL Sbjct: 1238 LPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGL 1271 Score = 62.4 bits (150), Expect = 2e-09 Identities = 133/528 (25%), Positives = 164/528 (31%), Gaps = 80/528 (15%) Query: 454 GGAPTPAPSIFNRSARPFTPGLQ-GQRPTTTSVIFRPLAPKRANDSLGGLSPA------P 506 GG T P P PG + G + S I ++P+R + L P P Sbjct: 752 GGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811 Query: 507 PPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATS----SLYIPAP------- 555 PP P+ L S G P P + ++S + +S S IP+P Sbjct: 812 PP------PSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTE 865 Query: 556 SRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSAR-------PEAPAPGPGAPEPPS 608 S PG PP PP MT + P P + P P PG G P PP Sbjct: 866 SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPP- 924 Query: 609 AREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGA 668 +P A L G PG P P + P GA Sbjct: 925 ------PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG-----AGIPLPPPLPGA 973 Query: 669 ESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM--APKTPPPMTPKTPPPVA 726 P G + G LP PPP+ A PPP P P Sbjct: 974 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1033 Query: 727 PKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRP 786 P P G+ AGIP PP L G G + P PG G P Sbjct: 1034 PPLPGAGIPP---PPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPP 1087 Query: 787 RSPSPTPSLPPSWKYSPNIRAPPP-------IAYNPLLSPFFPQAARTLPKAQSQGPRAT 839 P P +PP P + PPP I P L LP A P Sbjct: 1088 PPPLPGAGIPPP-PPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146 Query: 840 PKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQP-T 898 P+ GI P L A +PP P +G P + + P P P Sbjct: 1147 PRVGIP-------PPPPLPGA-----GIPPPPPLPGAGIPPPPPLPGV---GIPPPPPLP 1191 Query: 899 AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASP 946 + P P A P+ + AP P P PPP G G P Sbjct: 1192 GVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAP-PLPPP----GTGIPP 1234 Score = 47.4 bits (111), Expect = 7e-05 Identities = 43/135 (31%), Positives = 47/135 (34%), Gaps = 15/135 (11%) Query: 408 VEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRS 467 + P L G G+ PP P A + PP PLP P P PG G P P P + Sbjct: 1151 IPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP--LPGA 1204 Query: 468 ARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPS 527 P P L G PL P G PPP L GP LP S Sbjct: 1205 GIPPPPPLPGMGIPPAPA--PPLPPP-------GTGIPPPPLLPVSGPPLLPQVGSSTLP 1255 Query: 528 HAPVSGSPSTPRSSG 542 V G P SG Sbjct: 1256 TPQVCGFLPPPLPSG 1270 Score = 44.7 bits (104), Expect = 4e-04 Identities = 48/156 (30%), Positives = 54/156 (34%), Gaps = 16/156 (10%) Query: 96 PSPHELQVLSPLSPLSPEPPGA--PVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEK 153 P P LQ L P P PGA P P PL + P G A Sbjct: 897 PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956 Query: 154 PRRPRRRGPTRPTPPGA----PPDEVYLSDSPAEPAPT--IPGPPSQGDSRVSSPSWEDG 207 P P P P PGA PP P P P IP PP + + P G Sbjct: 957 PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1016 Query: 208 AALQPPPAEALLLPHGPLRPGPHL----IPMVGPVP 239 A + PPP LP + P P L IP P+P Sbjct: 1017 AGIPPPPP----LPGAGIPPPPPLPGAGIPPPPPLP 1048 Score = 43.9 bits (102), Expect = 7e-04 Identities = 91/362 (25%), Positives = 115/362 (31%), Gaps = 65/362 (17%) Query: 601 PGAPE-PPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLV--- 656 PG P PP A + + ++ RR + +P + ++ P P LL Sbjct: 764 PGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQG 823 Query: 657 QNLDEKPRAGGAE--SGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTP 714 Q + P + E + E S +CN P LP + P P Sbjct: 824 QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSP------PPLPCTESSSSMPGLGMVP 877 Query: 715 PPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVV 774 PP PPP L G+ S IP+PP LQG L + Sbjct: 878 PP-----PPP----------LPGMTVPTLPSTAIPQPPPLQGT-EMLPPPPPPLPGAGIP 921 Query: 775 EGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQ 834 P PG G P P P +PP P PPP PL P LP A Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPPP-PPLPGAAIPPP---PPLPGAGIP-LPPPLPGAGIP 976 Query: 835 GPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPA 894 P P GI P L A +PP P +G P P Sbjct: 977 PPPPLPGAGIP-------PPPPLPGA-----GIPPPPPLPGAGIP------------PPP 1012 Query: 895 PQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVA 954 P P A + P P A P L A +P P P P A G+ P G + Sbjct: 1013 PLPGA-GIPPPPPLPGAGIPPPPP-----LPGAGIPPPPPLPGA--GIPPPPPLPGAGIP 1064 Query: 955 RP 956 P Sbjct: 1065 PP 1066 Score = 43.5 bits (101), Expect = 0.001 Identities = 42/144 (29%), Positives = 51/144 (35%), Gaps = 21/144 (14%) Query: 106 PLSPLSPEPP----GAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRG 161 P + + P PP G P+P PL + PP G P P Sbjct: 949 PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1008 Query: 162 PTRPTPPGA--PPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALL 219 P P PGA PP P P IP PP + + P GA + PPP Sbjct: 1009 PPPPPLPGAGIPPP-------PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---- 1057 Query: 220 LPHGPLRPGPHL----IPMVGPVP 239 LP + P P L IP P+P Sbjct: 1058 LPGAGIPPPPPLPGAGIPPPPPLP 1081 Score = 43.5 bits (101), Expect = 0.001 Identities = 42/150 (28%), Positives = 52/150 (34%), Gaps = 16/150 (10%) Query: 106 PLSPLSPEPP----GAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRG 161 P + + P PP G P P PL + PP G P P Sbjct: 1114 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGI 1173 Query: 162 PTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALL-- 219 P P PG V + P P IP PP + + P G + P PA L Sbjct: 1174 PPPPPLPG-----VGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPP 1228 Query: 220 ---LPHGPLRP--GPHLIPMVGPVPHPVAE 244 +P PL P GP L+P VG P + Sbjct: 1229 GTGIPPPPLLPVSGPPLLPQVGSSTLPTPQ 1258 Score = 42.4 bits (98), Expect = 0.002 Identities = 43/140 (30%), Positives = 49/140 (35%), Gaps = 15/140 (10%) Query: 109 PLSPEPPGA--PVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPT 166 PL P PGA P P PL + PP G P P P P Sbjct: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024 Query: 167 PPGA--PPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPA-EALLLPHG 223 PGA PP P P IP PP + + P GA + PPP +P Sbjct: 1025 LPGAGIPPP-------PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1077 Query: 224 PLRPGPHLIPMVGPVPHPVA 243 P PG + P P P P A Sbjct: 1078 PPLPGAGIPP---PPPLPGA 1094 Score = 42.4 bits (98), Expect = 0.002 Identities = 42/148 (28%), Positives = 51/148 (34%), Gaps = 18/148 (12%) Query: 106 PLSPLSPEPP----GAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRG 161 P + + P PP G P P PL + PP G P P Sbjct: 1026 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1085 Query: 162 PTRPTPPGA------PPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPA 215 P P PGA P V + P P IP PP + + P GA + PPP Sbjct: 1086 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1145 Query: 216 EALLLPHGPLRPGPHL----IPMVGPVP 239 LP + P P L IP P+P Sbjct: 1146 ----LPRVGIPPPPPLPGAGIPPPPPLP 1169 Score = 37.4 bits (85), Expect = 0.069 Identities = 70/268 (26%), Positives = 95/268 (35%), Gaps = 55/268 (20%) Query: 500 GGLSPAPPPFLSSQGPTPLPSFT------SGVPSHAPVSGSPSTPRSSGPVTATSSLYIP 553 G PA PP S P SG AP GSP T ++ ++ Sbjct: 228 GAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAP--GSPDTEQALSALSDLPESLAA 285 Query: 554 AP---SRPVTPGGAP--EPPAPPSA--AAMTSTASIFLSAPLRPSARPEAPAPGPGAPEP 606 P +P +PGG P E P+ P+A AA S +S P A AP GA + Sbjct: 286 EPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDT 345 Query: 607 PSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG 666 E+ A R PG+E PE+ ++ P+ Sbjct: 346 DEEGEEDAFEDAPRGS----------------PGEEWA-----PEV------GEDAPQRL 378 Query: 667 GAESGPEEDALSLGAEACNFMQPVGA---RSYKTLPHVTP-----KTPPPMAPKTPPPMT 718 G E PEE+A A A + A R +K P +TP T +P P + Sbjct: 379 GEE--PEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQS 436 Query: 719 PKTPPPVAPKPP---SRGLLDGLVNGAA 743 P P + +P SRG L + AA Sbjct: 437 PNQSPRIKRRPEPSLSRGSRTALASVAA 464 Score = 36.2 bits (82), Expect = 0.15 Identities = 41/140 (29%), Positives = 48/140 (34%), Gaps = 19/140 (13%) Query: 112 PEPPGAPVPQPLQ--PGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPG 169 P PP P + PG PP G T A P+ P +G T PP Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAI---PQPPPLQG-TEMLPPP 911 Query: 170 APPDEVYLSDSPAEPAPTIPG------PPSQGDSRVSSPSWEDGAALQPPPAEALLLPHG 223 PP L + P P +PG PP G P A PPP +P Sbjct: 912 PPP----LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP 967 Query: 224 PLRPGPHLIPMVGPVPHPVA 243 P PG + P P P P A Sbjct: 968 PPLPGAGIPP---PPPLPGA 984 Score = 35.4 bits (80), Expect = 0.26 Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 7/119 (5%) Query: 127 SLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAP 186 ++ SPP + G P P PT P+ P + ++ P P Sbjct: 854 NIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP 913 Query: 187 TIPG------PPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVP 239 +PG PP G + P PPP +P P PG IP+ P+P Sbjct: 914 PLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAG-IPLPPPLP 971 Score = 32.3 bits (72), Expect = 2.2 Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 406 ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFN 465 A + P L G G+ P PP + PP PL PV+ P G + P P + Sbjct: 1204 AGIPPPPPLPGMGIPPAPAPPLPPPGTGI-PPPPL-LPVSGPPLLPQVGSSTLPTPQVCG 1261 Query: 466 RSARPFTPGLQG 477 P GL G Sbjct: 1262 FLPPPLPSGLFG 1273 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 90.1 bits (222), Expect = 9e-18 Identities = 200/804 (24%), Positives = 279/804 (34%), Gaps = 147/804 (18%) Query: 207 GAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQ 266 GAA + P A A G L P P P P P A + ++ +RA + Sbjct: 11 GAAARTPAARA----PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 Query: 267 EKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYT----LVSFGAAAGT--- 319 +I E+ + S T++ NP S+ + R K T + S G A+GT Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126 Query: 320 ----------GAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRAS 369 AEE +E+ + AR T+ +P + A +R S Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP------SPAMARRS 180 Query: 370 EGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQE-------LARVEPAAMLNGEGLQSP 422 G+ +G S R E R+ S+++ AR P+A G GLQ P Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA---GGGLQRP 237 Query: 423 PRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTT 482 A S P++SP P AP+ ++P GLQ RP Sbjct: 238 ----------ASRSLSSSATPLSSPARSGPSARGTPRAPA---HPSQPKPKGLQALRPPQ 284 Query: 483 TSVIFRPLAPKRANDSLGGLS-PAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSS 541 + + AP S L+ P+P L SQ P LP+ P + ++ +TP Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA----TPHSSSLTCQLATPLPL 340 Query: 542 GPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTS--------TASIFLSAPLRPSAR 593 P P+PS P + P PPA P + A TS T S S PL P A Sbjct: 341 AP---------PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 391 Query: 594 PEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELL 653 P AP P PP + S PA+ P + +PN + Sbjct: 392 PPPQAP-PALALPP--LQAPPSPPAS---------------PPLSPLATPSPQAPNALAV 433 Query: 654 SLVQ---NLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMA 710 L+Q + P S P +S A + P A P PP Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA--------APPLQVPPSP 485 Query: 711 PKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRAD 770 P +PP TPPP AP P + L + + PP Sbjct: 486 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP------------------ 527 Query: 771 RYVVEGTPGPGLGPRPRSP-SPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLP 829 ++ P P ++P SP+ SLP S +P +APP +A L P P A+ TL Sbjct: 528 ---LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL- 583 Query: 830 KAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIAS---------GSPK 880 Q PR P G D P +L A+ PP+ P ++ S Sbjct: 584 ----QAPRRPPTPG---PDTSVSGP-RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 635 Query: 881 TARVQEIRRF-STPAPQPTAEPLAPTVLAP-RAATTLDEPIWRTELASAP-VPSPAPPPE 937 T+ +E+R + S P A P LA A P AP P P PP Sbjct: 636 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 695 Query: 938 APRGLGASPSSCGFQVARPRFSAT 961 P G++ C SAT Sbjct: 696 GP---GSADGLCTIYETEGPESAT 716 Score = 90.1 bits (222), Expect = 9e-18 Identities = 197/781 (25%), Positives = 268/781 (34%), Gaps = 124/781 (15%) Query: 110 LSPEPPGAP-VPQPLQPGSLRSPPDSEAYYGETDSD-ADGPATQEKPRRPRRRGPTRPTP 167 L+P PPG+P P P+ P +LR + A + ++ A G P R GPTR Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA- 83 Query: 168 PGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRP 227 S PA PP+ G + P+ P P + G RP Sbjct: 84 ----------GTSSRNPASR---PPASGRGERAPPA----KNTSPGPVSSPGRASGTTRP 126 Query: 228 GPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAA 287 GP +G ++ + T + K + + +L + ++ T+ Sbjct: 127 GP-----LGQKGLRISAEETVA---RGKATEAPKRSALSAGARRD------------TSG 166 Query: 288 PNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLT 347 P P + M ++ R AAGT E G+P + S R Sbjct: 167 PTPGTPSPAMARRSR-------------AAGT----EVGLPRPAPSARPRPPTEGPRKSV 209 Query: 348 NQSDWDSPYLDMELARAGSRASEGQGSGLGGQLS-EVSGRGVQLFEQQRQRADSSTQELA 406 + + S AR A G GL S +S L R + A Sbjct: 210 SSASEHSTTEPSPAARRRPSA----GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265 Query: 407 RVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNR 466 P+ Q P+ A V PP AP P P TP+PS + Sbjct: 266 PAHPS--------QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP---LATPSPSAALQ 314 Query: 467 SARPFTPGLQGQRPTTTSVIFR--PLAP--KRANDSLGGLSPAPPPFLSSQGPTPLPSFT 522 S P T + T + PLAP A SL L P+PP SQ T L S T Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL-PSPPATPPSQATTSLGSPT 373 Query: 523 SGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP--EPPAPPSAAAMTSTA 580 +H+ + P +P ++ P A +L +P P +P +P P A PS A + A Sbjct: 374 LQA-THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 432 Query: 581 SIFLSAPLRPSARPEAPAP-GPGAPEP--PSAREQRISVPAARTGILQEARRRGTRKQMF 637 L AP P P AP P A P PSA + P+ LQ M Sbjct: 433 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM- 491 Query: 638 RPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKT 697 P +P P +Q P+A A + P AL + +F + Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP--SPPASFPGQAPFSPSAS 549 Query: 698 LPHVTPKTPPPMAPKT-------PPPMTPKTPPPVAPKPPSRGLLDGLVNG----AASSA 746 LP TPPP AP PP P +P AP+ P D V+G A + Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 609 Query: 747 GIPEPPRLQGR---GGELFAKRQSRADRYVVE--GTPGPGLGPRPRSPSPTPSL----PP 797 G P PP G A S A E G G SP P L P Sbjct: 610 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 669 Query: 798 SWKYSPNIRAPP---------PIAYNPLLSPFFPQAARTLPKAQSQGPR-ATPKQGIKAL 847 +W P APP P+ + P P T+ +++GP ATP G AL Sbjct: 670 AWSRGP---APPLAFRGAPGAPLPWPPATGPGSADGLCTI--YETEGPESATPAPG--AL 722 Query: 848 D 848 D Sbjct: 723 D 723 Score = 87.8 bits (216), Expect = 4e-17 Identities = 138/571 (24%), Positives = 196/571 (34%), Gaps = 97/571 (16%) Query: 424 RAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTT 483 + A AA P+ + +PRP G+P P P P TP Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRP----PGSPRPPP--------PVTPAALRVLGAAG 51 Query: 484 SVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRS--S 541 +V +PLA + GG+ A P P P+ ++G S P S P++ R + Sbjct: 52 AVGRKPLAERA-----GGIGGATIP---ESAPRAGPTRSAGTSSRNPASRPPASGRGERA 103 Query: 542 GPVTATSSLYIPAPSRP---VTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPS----ARP 594 P TS + +P R PG + SA + AP R + AR Sbjct: 104 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA-TEAPKRSALSAGARR 162 Query: 595 EAPAPGPGAPEPPSAREQR-----ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN 649 + P PG P P AR R + +P G RK + E + P+ Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV-SSASEHSTTEPS 221 Query: 650 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 709 P +P AGG P +LS A + G + TP+ P Sbjct: 222 PA-------ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA-----RGTPRAPAHP 269 Query: 710 APKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEP-PRLQGRGGELFAKRQSR 768 + P + PP V PP + L ++S P P LQ + Sbjct: 270 SQPKPKGLQALRPPQVT--PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHS 327 Query: 769 ADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTL 828 + TP P L P P+PS PPS + P+ A PP L QA + Sbjct: 328 SSLTCQLATPLP-LAP------PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 380 Query: 829 PKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTP------GPIASGSPKTA 882 + P ATP +A + P Q PP+P P+A+ SP+ Sbjct: 381 LPSPPLSPLATPPP--QAPPALALPPLQ----------APPSPPASPPLSPLATPSPQAP 428 Query: 883 RVQEIR----RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPV--------- 929 + FS P P P +P P + + LA+ P+ Sbjct: 429 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488 Query: 930 ----PSPAPPPEAPRGLGASPSSCGFQVARP 956 PS PPP+AP L A P Q+A+P Sbjct: 489 PPMSPSATPPPQAPPPLAAPP----LQLAKP 515 Score = 50.1 bits (118), Expect = 1e-05 Identities = 46/160 (28%), Positives = 60/160 (37%), Gaps = 13/160 (8%) Query: 96 PSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPR 155 P P LQ L P P AP PL L +P S A ++ + PAT Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAAL--QSQAPPTLPATPHSSS 329 Query: 156 RPRRRG---PTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQP 212 + P P P APP L P+ PA PPSQ + + SP+ + + P Sbjct: 330 LTCQLATPLPLAPPSPSAPPS---LQTLPSPPAT----PPSQATTSLGSPTLQATHSFLP 382 Query: 213 -PPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYT 251 PP L P P L P+ P P + L+ T Sbjct: 383 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 422 Score = 49.3 bits (116), Expect = 2e-05 Identities = 67/271 (24%), Positives = 93/271 (34%), Gaps = 33/271 (12%) Query: 704 KTPPPMAPK--TP-PPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG-IPEPPRLQGRGG 759 +TP AP TP PP +P+ PPPV P V GAA + G P R G GG Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPVTPAALR-------VLGAAGAVGRKPLAERAGGIGG 67 Query: 760 ELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSP 819 + RA GT RP + PP+ SP P+ SP Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP----------GPVSSP 117 Query: 820 FFPQAARTLPKAQSQGPRATPKQGI---KALDFMRHQPYQLKTAMFCFDEVPPTPGPIAS 876 +G R + ++ + KA + + P TP P + Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177 Query: 877 GSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPP 936 + A + P P P+A P PT ++ ++ E + P P+ P Sbjct: 178 RRSRAAGTE----VGLPRPAPSARPRPPTEGPRKSVSSASE-----HSTTEPSPAARRRP 228 Query: 937 EAPRGLGASPSSCGFQVARPRFSATRTGLQA 967 A GL S A P S R+G A Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSA 259 Score = 45.4 bits (106), Expect = 3e-04 Identities = 34/124 (27%), Positives = 47/124 (37%), Gaps = 19/124 (15%) Query: 106 PLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRP 165 P+SP + PP AP P P L PP PA P + P Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAP-----------PALATPPLQ------ALP 532 Query: 166 TPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPL 225 +PP + P + S S + P + PP Q +++P + PP + L P P Sbjct: 533 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ--VPPSPPASPTLQAPRRPP 590 Query: 226 RPGP 229 PGP Sbjct: 591 TPGP 594 Score = 45.1 bits (105), Expect = 3e-04 Identities = 42/151 (27%), Positives = 57/151 (37%), Gaps = 19/151 (12%) Query: 99 HELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPR 158 H PLSPL+ PP AP L P L++PP A S P P+ P Sbjct: 378 HSFLPSPPLSPLATPPPQAPPALALPP--LQAPPSPPA------SPPLSPLATPSPQAPN 429 Query: 159 RRG----PTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPP 214 +PP +PP + S + P PPSQ +++P LQ PP Sbjct: 430 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP------PLQVPP 483 Query: 215 AEALLLPHGP-LRPGPHLIPMVGPVPHPVAE 244 + P P P P P + P +A+ Sbjct: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAK 514 Score = 40.4 bits (93), Expect = 0.008 Identities = 101/463 (21%), Positives = 138/463 (29%), Gaps = 57/463 (12%) Query: 92 PVQSPSPHE----LQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADG 147 P +PH Q+ +PL P P P Q L P + G A Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 378 Query: 148 PATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDG 207 P P PP APP L+ P + P+ P P SP Sbjct: 379 SFLPSPP-----LSPLATPPPQAPP---ALALPPLQAPPSPPASPPLSPLATPSP----- 425 Query: 208 AALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQE 267 Q P A A+ L P P P P+ P P + ++ + T ++ A LQ Sbjct: 426 ---QAPNALAVHLLQAPFSPPPS-PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 481 Query: 268 KSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGV 327 A A+ AP P + L K +A A T + Sbjct: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--------PALATPPLQALPS 533 Query: 328 PPTS---ESELDEEAFSDARSLTNQSDWDSPYLDMELAR------AGSRASEGQGSGLGG 378 PP S ++ A L P L L + A + G Sbjct: 534 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 593 Query: 379 QLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQS-PPRAQSAPPEAAVLPP 437 + VSG + L S P++ L+G L A S P E Sbjct: 594 PDTSVSGPRLTLALAPGPPPPPSR------SPSSTLSGPDLAGHSSSATSTPEELRGYDS 647 Query: 438 SPLPAPVASPRP------FQPGGGAPTPAPSIFNRSA----RPFTPGLQGQRPTTTSVIF 487 P ASP P P + PAP + R A P+ P I+ Sbjct: 648 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 707 Query: 488 RPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAP 530 P+ A + G L P P P + G +G S +P Sbjct: 708 ETEGPESATPAPGALDPGPSP--GTSGGKAAAGAGAGASSRSP 748 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 90.1 bits (222), Expect = 9e-18 Identities = 217/913 (23%), Positives = 307/913 (33%), Gaps = 155/913 (16%) Query: 111 SPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGA 170 +P+PP P P ++ + P + G T PR P P RP PPG Sbjct: 980 APDPPPRPKPVKMKVNRMLQPVPKQE--GRT------VVVVNNPRAPLGPVPVRP-PPG- 1029 Query: 171 PPDEVYLSDSPAEPAPTIPGPPSQ---GDSRVS-SPSWEDGAALQPPPAEALLLPHGPLR 226 P A PGP Q VS SP+ PP LL PL+ Sbjct: 1030 ----------PELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLL---PPLQ 1076 Query: 227 PGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTA 286 P +P V P P V + T +L K A + L+ Sbjct: 1077 PNSGSLPQVLPSPLGVLSGTSRPPTP-----------TLSLKPTPPAPVR-------LSP 1118 Query: 287 APNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSL 346 AP P S +L K YT F AA T T+ A + L Sbjct: 1119 APPPGSSSLL---KPLTVPPGYT---FPPAAATTTSTTTATATTTAVPAPTPA---PQRL 1169 Query: 347 TNQSDWDSPYLDMELARAGSRASEGQG--SGLGGQLS---EVSGRGVQLFEQQ-RQRADS 400 D + E+ G AS Q + GG ++ G + L Q RQ A Sbjct: 1170 ILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVG 1229 Query: 401 STQELAR--VEPAAMLNGEGLQSPPR----AQSAPPEAAVLPPSPLPAPVASPRPFQPGG 454 + L R V + L S P Q+ P P S LP+ S P G Sbjct: 1230 QPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGL 1289 Query: 455 GAPTPA----PSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLG---GLSPAP- 506 P A P++ N + Q R T V PLAP S G L+P P Sbjct: 1290 SLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPV--PPLAPAPRPPSSGLPAVLNPRPT 1347 Query: 507 --------PPFLSSQGPTPLPSFTSGVPS--HAPVSGSPSTPRSSGPVTATSSLYIPAPS 556 P +++ P P P+ + H+P ++ + P+T +S L++P+ Sbjct: 1348 LTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSL 1407 Query: 557 RPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISV 616 P P + P A+ ++ST S+ LS+ L S PAP P + ++V Sbjct: 1408 PGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAP--LTV 1465 Query: 617 PAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDA 676 A+ +L S P L +V P + + P A Sbjct: 1466 SASGPALL---------------------TSVTPPLAPVVPAAPGPPSLAPSGASPSASA 1504 Query: 677 LSLG---AEACNFMQPVG-----ARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPK 728 L+LG A + + Q G A + +P + P +P P +P P AP Sbjct: 1505 LTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPN 1564 Query: 729 P-------------PSRGLLDGLVNGAASSAGI----PEPPRL-------QGRGGELFAK 764 P S+ L L AA I P PP + A Sbjct: 1565 PAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLAS 1624 Query: 765 RQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQA 824 Q+ TPG L P+PTP L PS S P P+ +PL SP Q Sbjct: 1625 SQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPS---STQTMLPAPVP-SPLPSPASTQT 1680 Query: 825 ARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKT-AMFCFDEVPPTPGPIAS--GSPKT 881 P ++P Q + P+ +T ++ + PTP S P Sbjct: 1681 LALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPL 1740 Query: 882 ARVQEIRRFSTPAPQPTAEPLAPT-----VLAPRAAT-TLDEPIWRTELASAPVPSPAPP 935 Q + P P A P+ P LAP +++ +L P L +P P P Sbjct: 1741 GPTQTLSLAPAP-PLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLG 1799 Query: 936 PEAPRGLGASPSS 948 P A + L +P+S Sbjct: 1800 PAAAQTLALAPAS 1812 Score = 76.3 bits (186), Expect = 1e-13 Identities = 135/549 (24%), Positives = 185/549 (33%), Gaps = 77/549 (14%) Query: 422 PPRAQSAPPEA----AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG 477 PP A + P + AVL P P P P P AP P P++ RP + Sbjct: 1325 PPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTL----VRPLLKLVHS 1380 Query: 478 QRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPST 537 P S AP + L S P P + P P+P+ + P +PVS + S Sbjct: 1381 PSPEV-SASAPGAAPLTISSPLHVPSSLPGP---ASSPMPIPNSS---PLASPVSSTVSV 1433 Query: 538 PRSSG-PVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEA 596 P SS P++ ++L PA + P AP + A +TS ++ PL P P A Sbjct: 1434 PLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTS-----VTPPLAPVV-PAA 1487 Query: 597 PAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLV 656 P P AP S +++ A L ++ G P +S P L S V Sbjct: 1488 PGPPSLAPSGASPSASALTLGLATAPSLSSSQTPG------HPLLLAPTSSHVPGLNSTV 1541 Query: 657 QNLDEKPRA-GGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPP 715 A + P A + + + P + S + P P A P Sbjct: 1542 APACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPS 1601 Query: 716 PMTPKTPPPV-APKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVV 774 P P P PV AP P + +L A+S +P G L + A Sbjct: 1602 PAPPLAPLPVLAPSPGAAPVL------ASSQTPVPVMAPSSTPGTSLASASPVPA----- 1650 Query: 775 EGTPGPGLGPRPRS---PSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKA 831 P P L P P+P PS PS + + P +A P L P +L Sbjct: 1651 ---PTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALA--PTLGGSSPSQTLSLGTG 1705 Query: 832 QSQGPRATPKQGIKALDFMRHQPYQL----------KTAMFCFDEVPP------------ 869 QGP T + + P Q T PP Sbjct: 1706 NPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPA 1765 Query: 870 ---TPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTEL-- 924 T P +S + A +PAP PT P A LA A+T + L Sbjct: 1766 HTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVV 1825 Query: 925 -ASAPVPSP 932 AS P P Sbjct: 1826 SASGAAPLP 1834 Score = 74.3 bits (181), Expect = 5e-13 Identities = 204/918 (22%), Positives = 302/918 (32%), Gaps = 142/918 (15%) Query: 91 GPVQSPSPHELQVLS-----PLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDA 145 GPV P L V + PL P S PPG + PLQP S P + G S Sbjct: 1039 GPVPQVLPASLMVSASPAGPPLIPAS-RPPGPVLLPPLQPNSGSLPQVLPSPLGVL-SGT 1096 Query: 146 DGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWE 205 P T +P P R +P P L P T P + S ++ + Sbjct: 1097 SRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATT 1156 Query: 206 DGA-ALQPPPAEALLLPHGPLRPGPHLIPMVGPVP----HPVAE---DLTTTYTQKAKQA 257 A P P +L P R + +G + PVA T+ + + Sbjct: 1157 TAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKL 1216 Query: 258 KLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPH----------------SKGVLMFKKR 301 L A+ +++ ++ + + R + L++A H + G Sbjct: 1217 TLTGAQ-VRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVL 1275 Query: 302 RQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMEL 361 T G + A + VPPT + + + Q+ D L Sbjct: 1276 PSSTPSTTPAPTGLSLPLAANQ---VPPTMVNNTGV-----VKIVVRQAPRDGLTPVPPL 1327 Query: 362 ARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQS 421 A A S G + L + + GR + RA T L R P L + S Sbjct: 1328 APAPRPPSSGLPAVLNPRPTLTPGR-LPTPTLGTARAPMPTPTLVR--PLLKL----VHS 1380 Query: 422 P-PRAQSAPPEAAVLP-------PSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTP 473 P P ++ P AA L PS LP P +SP P +P S + P + Sbjct: 1381 PSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTV---SVPLSS 1437 Query: 474 GLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSG 533 L PTT P A+ L + + P +S+ GP L S T + P + Sbjct: 1438 SLPISVPTT--------LPAPASAPL-TIPISAPLTVSASGPALLTSVTPPLAPVVPAAP 1488 Query: 534 SPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSAR 593 P + SG + S+L + + P + + P P A TS+ L++ + P+ Sbjct: 1489 GPPSLAPSGASPSASALTLGLATAPSL--SSSQTPGHPLLLAPTSSHVPGLNSTVAPACS 1546 Query: 594 P------EAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNS 647 P +P P AP P A+ ++ ++ + L M P S Sbjct: 1547 PVLVPASALASPFPSAPNPAPAQASLLAPASSASQALAT-----PLAPMAAPQTAILAPS 1601 Query: 648 PNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPP 707 P P L L L P A + + + + A P P Sbjct: 1602 PAPPLAPL-PVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASP-------VPAPTP 1653 Query: 708 PMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQS 767 +AP + M P P P P S L L A + G P + G Q Sbjct: 1654 VLAPSSTQTMLPAPVPSPLPSPASTQTL-ALAPALAPTLGGSSPSQTLSLG---TGNPQG 1709 Query: 768 RADRYVVEGTPGPGLGPRPR---SPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQA 824 + TP L P P S +P P L P+ S + PP+A SP P Sbjct: 1710 PFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLS--LAPAPPLA---PASPVGPAP 1764 Query: 825 ARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARV 884 A TL A A+ + A P ++T +P P+ + P A+ Sbjct: 1765 AHTLTLAP-----ASSSASLLA-------PASVQTLTL-------SPAPVPTLGPAAAQT 1805 Query: 885 QEIRRFSTPAPQPTAEPLA---------PTVLAPRAATTLDEPIWRTELASAPVP----- 930 + ST +P A L P + R + DEP T + P P Sbjct: 1806 LALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTAT 1865 Query: 931 ---------SPAPPPEAP 939 P PPP +P Sbjct: 1866 SFGGPRPRRQPPPPPRSP 1883 Score = 67.4 bits (163), Expect = 6e-11 Identities = 197/817 (24%), Positives = 266/817 (32%), Gaps = 193/817 (23%) Query: 105 SPLSPLSPEPPGAPVPQPLQPG--SLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGP 162 +P L+P PP AP P+P G ++ +P + P P R P Sbjct: 1316 APRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLT-----------PGRLPTPTLGTARAP 1364 Query: 163 TRPTPPGAPPDEVYLSDSPAEPAPTIPGP-PSQGDSRVSSPSWEDGAALQPPPAEALLLP 221 PTP P + E + + PG P S + PS G A P P Sbjct: 1365 M-PTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPI------ 1417 Query: 222 HGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIA 281 P+ P+ PV V+ L+++ A + I T + Sbjct: 1418 -------PNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGP 1470 Query: 282 SLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFS 341 +LLT+ P + V AA G + G P++ + + Sbjct: 1471 ALLTSVTPPLAPVV------------------PAAPGPPSLAPSGASPSASALT--LGLA 1510 Query: 342 DARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSS 401 A SL++ P L LA S G S + S V L + + Sbjct: 1511 TAPSLSSSQTPGHPLL---LAPTSSHVP-GLNSTVAPACSPVLVPASALASPFPSAPNPA 1566 Query: 402 TQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSP----LPAPVASPRPFQPGGGAP 457 + + + PA+ + + P A A P+ A+L PSP P PV +P P G AP Sbjct: 1567 PAQASLLAPAS--SASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSP----GAAP 1620 Query: 458 ------TPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 511 TP P + A TPG + LAP L PAP P Sbjct: 1621 VLASSQTPVPVM----APSSTPGTSLASASPVPAPTPVLAPSSTQTML----PAPVP--- 1669 Query: 512 SQGPTPLPSFTSGV---PSHAPVSG--SPS------TPRSSGPVTATSSLYIPAPSRPVT 560 P P P+ T + P+ AP G SPS T GP + PA S T Sbjct: 1670 --SPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPT 1727 Query: 561 PGG----APEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISV 616 P AP PP P T T S+ + PL P A P PAP P++ + Sbjct: 1728 PAQTLSLAPGPPLGP-----TQTLSLAPAPPLAP-ASPVGPAPAHTLTLAPASSSASLLA 1781 Query: 617 PAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDA 676 PA+ + P T + L+L A + P A Sbjct: 1782 PAS------------VQTLTLSPAPVPTLGPAAAQTLAL---------APASTQSPASQA 1820 Query: 677 LSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP-------PPVAPKP 729 SL A P+ LP V+ P + ++ PP P T P P P Sbjct: 1821 SSLVVSASG-AAPLPVTMVSRLP-VSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPP 1878 Query: 730 PSRG--LLDGLVNGAASSAGIPEPPRLQGRGGEL---FAKRQSRADRYVVEGT------- 777 P R LD L E R + R L F ++ V GT Sbjct: 1879 PPRSPFYLDSL-----------EEKRKRQRSERLERIFQLSEAHGALAPVYGTEVLDFCT 1927 Query: 778 -PGPGLGP-RPRSPSPTPSLPPSWKYS----------------------------PNIRA 807 P P P PRSP PS P W Y+ P + A Sbjct: 1928 LPQPVASPIGPRSPG--PSHPTFWTYTEAAHRAVLFPQQRLDQLSEIIERFIFVMPPVEA 1985 Query: 808 PPPIAY----NPLLSPFFPQAARTLPKAQSQGPRATP 840 PPP + P L+P QAA A PRA P Sbjct: 1986 PPPSLHACHPPPWLAP--RQAAFQEQLASELWPRARP 2020 Score = 58.2 bits (139), Expect = 4e-08 Identities = 162/720 (22%), Positives = 238/720 (33%), Gaps = 130/720 (18%) Query: 111 SPEPPGAPVPQPLQ------PGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTR 164 +PE PG V + L+ G+ +P S T + +E+ RP R R Sbjct: 2387 APERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPR--PR 2444 Query: 165 PTPPGAPPDEVYLSDSPAE--------------PAPTIPGPPSQGD-SRVSSPSWEDGAA 209 PTP AP L P P +P PP SSP+ A Sbjct: 2445 PTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPA 2504 Query: 210 LQPPPAEA-------LLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRA 262 PPPA L+ P PL ++GP P++ +T +A+L Sbjct: 2505 CTPPPAHTPPPAQTCLVTPSSPL--------LLGPPSVPISASVTNLPLGLRPEAELCAQ 2556 Query: 263 ESLQEKSIKEAKTKCRTIASLLTAAPN---PHSKGVLMFKKRRQRAKKYTLVSFGAAAGT 319 +S++ A +SL P P + +L ++ +S +A + Sbjct: 2557 ALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKN--------LSLTPSAPS 2608 Query: 320 GAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQ 379 E +P E E + A ++ + + + P E S L Sbjct: 2609 LTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGE-ELPLCVSESNGLELPPSAASDEPLQEP 2667 Query: 380 LSEVSGRGVQLFEQQRQRAD-SSTQELARVEPAAMLNGEGLQSPPRAQSA--PPEAAVLP 436 L E +L E + + QEL E AA S P S PP Sbjct: 2668 L-EADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSA 2726 Query: 437 PSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRAN 496 + + RP QP P P + + L G+ T V+ +R Sbjct: 2727 DVEIRGQ-GTGRPGQP------PGPKVLRK--------LPGRLVT---VVEEKELVRRRR 2768 Query: 497 DSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPS 556 G S P + S + G PS +SG S+P GP A S +P P Sbjct: 2769 QQRGAASTLVPGVSET-------SASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPP 2821 Query: 557 RP-----------VTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPA-PGPGAP 604 + VT GG+PE A + T RP + +PA G G Sbjct: 2822 QQPFIARRHIELGVTGGGSPE---NGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVD 2878 Query: 605 EPPSAREQRIS-----VPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNL 659 E PS+ + + VP T I+ + +P + + PNP LLS V Sbjct: 2879 EAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNP-LLSPV--- 2934 Query: 660 DEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTP-PPM--------- 709 EK R G P+ L + + + PH +P TP PP+ Sbjct: 2935 -EKRRRG---RPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVA 2990 Query: 710 -----------APKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRG 758 PK PK PP +P+P +LD S G+ + QG+G Sbjct: 2991 NTVTTVTISTSPPKRKRGRPPKNPP--SPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQG 3048 Score = 50.8 bits (120), Expect = 6e-06 Identities = 144/607 (23%), Positives = 201/607 (33%), Gaps = 134/607 (22%) Query: 407 RVEPAAMLNGEGLQSP---PRAQSAPPEAAVLP------------PSPLPAP---VASP- 447 R+ PA L P P + PP AA P+P PAP + SP Sbjct: 1115 RLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPD 1174 Query: 448 -RPFQPGG--------GAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLA-----PK 493 + P G + P ++P T +QG + T T R LA P Sbjct: 1175 MQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPL 1234 Query: 494 RAND----SLGGL-----SPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPV 544 + N S GG PA + + PTP P+ PVS PS+ S+ P Sbjct: 1235 QRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPT---------PVSVLPSSTPSTTP- 1284 Query: 545 TATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPE---APAPGP 601 A + L +P + V PP+ T I + R P APAP P Sbjct: 1285 -APTGLSLPLAANQV----------PPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRP 1333 Query: 602 GAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDE 661 + P+ R P G L R M P P L+ + L Sbjct: 1334 PSSGLPAVLNPR---PTLTPGRLPTPTLGTARAPM-----------PTPTLVRPLLKLVH 1379 Query: 662 KPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKT 721 P PE A + GA P+ S +LP P + P P + P +P + Sbjct: 1380 SP-------SPEVSASAPGAAPLTISSPLHVPS--SLPG--PASSPMPIPNSSPLASPVS 1428 Query: 722 PPPVAPKPPSRGLLDGLVNGAASSAGIPEP---PRLQGRGGELFAKRQSRADRYVVEGTP 778 P S + A +SA + P P G + VV P Sbjct: 1429 STVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAP 1488 Query: 779 GP-GLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQ-GP 836 GP L P SPS + +L +P++ + + LL+P + +P S P Sbjct: 1489 GPPSLAPSGASPSAS-ALTLGLATAPSLSSSQTPGHPLLLAP----TSSHVPGLNSTVAP 1543 Query: 837 RATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ 896 +P L A P P P + + A ++ A Q Sbjct: 1544 ACSPV---------------LVPASALASPFPSAPNPAPAQASLLAP-------ASSASQ 1581 Query: 897 PTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARP 956 A PLAP + AP+ A LA +P P AP P GA+P Q P Sbjct: 1582 ALATPLAP-MAAPQTAI----------LAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVP 1630 Query: 957 RFSATRT 963 + + T Sbjct: 1631 VMAPSST 1637 Score = 48.5 bits (114), Expect = 3e-05 Identities = 97/432 (22%), Positives = 156/432 (36%), Gaps = 60/432 (13%) Query: 370 EGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAP 429 E +G G G + S +G G ++ + + ++ A +G P + Sbjct: 2360 EEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQ 2419 Query: 430 PEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRP 489 + PP PA PRP AP P P+ SA P L P S Sbjct: 2420 TRSTTTPPRCSPARERVPRP------APRPRPT--PASAPAAIPALV---PVPVSAPVPI 2468 Query: 490 LAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSS 549 AP + P+PPP P+ +P +S P+ P P + P T Sbjct: 2469 SAPNPITILPVHILPSPPP------PSQIPPCSS--PACTPPPACTPPPAHTPPPAQTC- 2519 Query: 550 LYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSA 609 + PS P+ G PP+ P +A++T+ L RPEA P S Sbjct: 2520 --LVTPSSPLLLG----PPSVPISASVTN---------LPLGLRPEAELCAQALASPESL 2564 Query: 610 REQRISVPAARTGILQEARRRG---TRKQMFRPGKEETKNSPNPELLSL----VQNLDEK 662 + SV ++ T L + ++ ++ +P+ L+L + N E+ Sbjct: 2565 --ELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQ 2622 Query: 663 PRAGGAESG-----PEEDALSLGAEACNFMQ-PVGARSYKTLPHVTPKTPPPMAPKTPPP 716 AE PE + L L N ++ P A S + P P A +T Sbjct: 2623 EAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDE------PLQEPLEADRTSEE 2676 Query: 717 MTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYV-VE 775 +T P +P+ P + + + SS+ P +G +R++ AD + + Sbjct: 2677 LTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSP---EGPSPARPPRRRTSADVEIRGQ 2733 Query: 776 GTPGPGLGPRPR 787 GT PG P P+ Sbjct: 2734 GTGRPGQPPGPK 2745 Score = 48.5 bits (114), Expect = 3e-05 Identities = 175/774 (22%), Positives = 250/774 (32%), Gaps = 168/774 (21%) Query: 92 PVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSE--AYYGETDSDADGPA 149 P +P P + +++P SPL PP P+ + L P++E A + + + Sbjct: 2509 PAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELAS 2568 Query: 150 TQEKPRRPRRRGPTRPTPPGA----PPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWE 205 P + P A P E LS +P+ P+ T+ +P Sbjct: 2569 VASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSA 2628 Query: 206 DGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESL 265 +G L P E LP +P P+ E L T Sbjct: 2629 EGTTLTVLP-EGEELPLCVSESNGLELPPSAASDEPLQEPLEADRT-------------- 2673 Query: 266 QEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEED 325 + + EAKT T++P K LV+ AA Sbjct: 2674 -SEELTEAKTP--------TSSPE----------------KPQELVTAEVAA-------- 2700 Query: 326 GVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQ------ 379 P TS S T+ + SP + GQG+G GQ Sbjct: 2701 --PSTSSS------------ATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKV 2746 Query: 380 LSEVSGRGVQLFEQ-------QRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPP-- 430 L ++ GR V + E+ ++QR +ST E +A ++S +S+PP Sbjct: 2747 LRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIG 2806 Query: 431 ---EAAVLPPSPLPAPVASP----RPFQ---PGGGAP----------TPAPSIFNRSARP 470 EAA P S LP P P R + GGG+P TP P++ R R Sbjct: 2807 GPCEAA--PSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITP-PAVKRRRGR- 2862 Query: 471 FTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP--------PPFLSSQ---GPTPL- 518 P + + P G P P P L Q GP PL Sbjct: 2863 --PPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLG 2920 Query: 519 --------------PSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGA 564 G P A P T S+G + S P P+TP Sbjct: 2921 PQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTP-LP 2979 Query: 565 PEPPAPPSAAAMT-STASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGI 623 P P + A T +T +I S P R RP PPS R ++ V + Sbjct: 2980 PLLVCPTATVANTVTTVTISTSPPKRKRGRP--------PKNPPSPRPSQLPVLDRDSTS 3031 Query: 624 LQEARRRGTRKQMFRPGKEETKNSP---NPELLSLVQNLDEKPRAGGAESGPE------E 674 + E+ G R+Q G+ E +S + L L + E G +SG + Sbjct: 3032 VLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQ 3091 Query: 675 DALSLGAEACNFMQPVGARSYKTLPHVTPK---TPPPMAPKTPPPMTPKTPPPVAPKPPS 731 D L L P G + +TPK T PP T K P A P Sbjct: 3092 DDLDLADSG-----PGGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPV- 3145 Query: 732 RGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPR 785 G G A + P L G ++ ++ + +GTP GPR Sbjct: 3146 -----GGSPGLAKRGRLQPPSPLGPEGSVEESEAEASGEEEEGDGTPRRRPGPR 3194 Score = 42.7 bits (99), Expect = 0.002 Identities = 137/573 (23%), Positives = 179/573 (31%), Gaps = 114/573 (19%) Query: 80 LVLTVQRLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYG 139 L+ V + E +P L + SPL S P A P P+ P+S Sbjct: 1374 LLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPI--------PNSSPLAS 1425 Query: 140 ETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPA-------------P 186 S P + P P + P P L+ S + PA P Sbjct: 1426 PVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVP 1485 Query: 187 TIPGPPSQGDSRVS------------SPSWEDGAALQPPPAEALLLPHGPLRPG------ 228 PGPPS S S +PS ++ Q P LL P PG Sbjct: 1486 AAPGPPSLAPSGASPSASALTLGLATAPSL---SSSQTPGHPLLLAPTSSHVPGLNSTVA 1542 Query: 229 ----PHLIPM--------VGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTK 276 P L+P P P P L + ++ A ++ A + Sbjct: 1543 PACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSP 1602 Query: 277 CRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGT-GAEEEDGVP-PTSESE 334 +A L AP+P + VL A T V A + T G P P Sbjct: 1603 APPLAPLPVLAPSPGAAPVL--------ASSQTPVPVMAPSSTPGTSLASASPVPAPTPV 1654 Query: 335 LDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQ 394 L + S SP LA A + A GS LS +G F Q Sbjct: 1655 LAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQ 1714 Query: 395 RQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGG 454 T L + L P P + L P+P P+A P P G Sbjct: 1715 -------TLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAP---PLA---PASPVG 1761 Query: 455 GAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQG 514 AP ++ P ++S LAP A+ LSPAP P L Sbjct: 1762 PAPAHTLTL---------------APASSSASL--LAP--ASVQTLTLSPAPVPTLGPAA 1802 Query: 515 PTPL---PSFTSGVPSHAP---VSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPP 568 L P+ T S A VS S + P PVT S L + + P T PP Sbjct: 1803 AQTLALAPASTQSPASQASSLVVSASGAAPL---PVTMVSRLPV-SKDEPDTLTLRSGPP 1858 Query: 569 APPSAAAMTSTASIFLSAPLRPSARPEAPAPGP 601 +PPS A P RP +P P P Sbjct: 1859 SPPSTATS-------FGGP-RPRRQPPPPPRSP 1883 Score = 39.3 bits (90), Expect = 0.018 Identities = 59/232 (25%), Positives = 79/232 (34%), Gaps = 7/232 (3%) Query: 64 LSHASAMSLIDASGNQLVLTVQRLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPL 123 L+ A ++S G+ L+L G + +P VL P S L+ P AP P P Sbjct: 1509 LATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPA 1568 Query: 124 QPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAP-PDEVYLSDSPA 182 Q L P S A A A Q P P P P AP P + S Sbjct: 1569 QASLL--APASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQ 1626 Query: 183 EPAPTIPGPPSQGDSRVS-SPSWEDGAALQPPPAEALL---LPHGPLRPGPHLIPMVGPV 238 P P + + G S S SP L P + +L +P P + P Sbjct: 1627 TPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPA 1686 Query: 239 PHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNP 290 P + + T Q Q S+ A + T A L+ AP P Sbjct: 1687 LAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGP 1738 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 88.2 bits (217), Expect = 3e-17 Identities = 115/465 (24%), Positives = 166/465 (35%), Gaps = 65/465 (13%) Query: 381 SEVSGRGVQLFEQQRQRADSS----TQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLP 436 SE RG QL E + R +S T + + P + S P PP P Sbjct: 578 SEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPP 637 Query: 437 PSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRAN 496 P P P P P P Q A + AP S LQ + ++ P P + Sbjct: 638 PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST---ITRLQNASQHSGALFKPPTPPVMQS 694 Query: 497 DSL--------GGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGP----- 543 S+ G+ P PPP P P P+ S + P +PS P+ S P Sbjct: 695 QSVKPQILVPPNGVVPPPPP------PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLK 748 Query: 544 ---VTATSSLYIPAPSRPVTPGGAPEPP-APP----SAAAMTSTASIFLSAPLRPSARPE 595 V + + P P P P AP PP APP + A TST ++ AP+ A P Sbjct: 749 IHQVQHITQVAPPTPPPP-PPIPAPLPPQAPPKPLVTIPAPTSTKTV---APVVTQAAPP 804 Query: 596 APAPGPGAPEPPSAREQRISV----PAARTGILQEARRRGTRKQMFRPGKEETKNSPNPE 651 P P P PP+ ++ P+ T + ++Q F + SP P Sbjct: 805 TPTP----PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPS 860 Query: 652 LLS-LVQNLDEKPRAGGAESGPEEDA-LSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 709 ++ + P ES P + ++ ++ ++ ++P +P PPP Sbjct: 861 VVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPP 920 Query: 710 A---------PKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGR--- 757 P +P P P PPP A P + G SS G +PP R Sbjct: 921 PESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS 980 Query: 758 -----GGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPP 797 G E ++ D V + TP G + P P+ PP Sbjct: 981 IKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP 1025 Score = 71.6 bits (174), Expect = 3e-12 Identities = 102/409 (24%), Positives = 137/409 (33%), Gaps = 86/409 (21%) Query: 567 PPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGI--- 623 PP P +T + S PL P P P P P P PP Q S P+A + Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQ--SAPSAGSAAPMF 664 Query: 624 --------LQEARRRGTRKQMFRPGKEETKNSPN--PELLSLVQNLDEKPRAGGAESGPE 673 LQ A + +F+P S + P++L + P P Sbjct: 665 VKYSTITRLQNASQHSGA--LFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG 722 Query: 674 EDALSLGAEAC-----NFMQPVGARSYKTLPHVT---PKTPPPMAPKTPPPMTPKTPPP- 724 L C F P + H+T P TPPP P P P+ P+ PP Sbjct: 723 SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPP-PPPIPAPLPPQAPPKP 781 Query: 725 --VAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGL 782 P P S + +V AA P P AK+Q + +P Sbjct: 782 LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP---------AKKQPAFPASYIPPSP---- 828 Query: 783 GPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQ 842 P P P P P+LP + PPP +P+ S Q A P P TP Sbjct: 829 -PTPPVPVPPPTLPKQQSFCAK---PPPSPLSPVPS-VVKQIASQFP------PPPTPPA 877 Query: 843 GIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPL 902 M QP + P P +A SP + + P QP++ P+ Sbjct: 878 -------MESQPLK------------PVPANVAPQSPPAVKAK-------PKWQPSSIPV 911 Query: 903 -APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCG 950 +P P ++L P P P PAPPP P +P G Sbjct: 912 PSPDFPPPPPESSLVFP------PPPPSPVPAPPPPPPPTASPTPDKSG 954 Score = 65.9 bits (159), Expect = 2e-10 Identities = 93/374 (24%), Positives = 130/374 (34%), Gaps = 85/374 (22%) Query: 398 ADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPF------- 450 A +ST+ +A V A PP + A+ +PPSP PV P P Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSF 846 Query: 451 --QPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRAN------------ 496 +P +P PS+ + A F P PT ++ +PL P AN Sbjct: 847 CAKPPPSPLSPVPSVVKQIASQFPPP-----PTPPAMESQPLKPVPANVAPQSPPAVKAK 901 Query: 497 -----DSLGGLSP---APPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATS 548 S+ SP PPP S P P PS P P + SP+ +S P T Sbjct: 902 PKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKT- 960 Query: 549 SLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPS-----------ARPEAP 597 S+ +PGG PP P +++ S++ P RPS A +P Sbjct: 961 -------SKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSP 1013 Query: 598 A----PGPGA-PEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPEL 652 + P P A P+P +++P G+LQ+ + GK+ P+P Sbjct: 1014 SKETLPPPAAPPKPGKLNLSGVNLP----GVLQQGCVSAKAPVLSGRGKDSVVEFPSP-- 1067 Query: 653 LSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM--- 709 P P E L L ++ S T P V P P Sbjct: 1068 ----------PSDSDFPPPPPETELPLPP-----IEIPAVFSGNTSPKVAVVNPQPQQWS 1112 Query: 710 ---APKTPPPMTPK 720 K PPP PK Sbjct: 1113 KMSVKKAPPPTRPK 1126 Score = 65.1 bits (157), Expect = 3e-10 Identities = 130/548 (23%), Positives = 186/548 (33%), Gaps = 132/548 (24%) Query: 426 QSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSV 485 Q APP PP P+PAP+ P +P P P + ++ P Q PT T Sbjct: 757 QVAPPTPP--PPPPIPAPLPPQAPPKPLVTIPAPTST---KTVAPVVT--QAAPPTPTPP 809 Query: 486 IFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTS--GVPSHAPVSGSPSTPR---S 540 + P A K+ + P+PP P LP S P +P+S PS + S Sbjct: 810 V--PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIAS 867 Query: 541 SGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEA---- 596 P T P +PV AP+ P A +SI + +P P PE+ Sbjct: 868 QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVF 927 Query: 597 ------PAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNS--- 647 P P P P PP+A T + PGK+ +K S Sbjct: 928 PPPPPSPVPAPPPPPPPTASP--------------------TPDKSGSPGKKTSKTSSPG 967 Query: 648 -----PNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVT 702 P P+ S +++ + GAE PE S+ + F P + S Sbjct: 968 GKKPPPTPQRNSSIKS------SSGAEH-PEPKRPSVDSLVSKFTPPAESGS-------- 1012 Query: 703 PKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGI--PEPPRLQGRGGE 760 P PPP AP P + L G+ G + P L GRG + Sbjct: 1013 -------------PSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKD 1059 Query: 761 LFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYS-PNIRAPPPIAYN--PLL 817 VVE P P S S P PP + P I P + N P + Sbjct: 1060 -----------SVVE-------FPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKV 1101 Query: 818 SPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASG 877 + PQ + + + P T + + + + + T +VP +P S Sbjct: 1102 AVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSV 1161 Query: 878 SP-------KTARVQEIRRF-STPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPV 929 P +T + + I R S + AEP A T+D+ + Sbjct: 1162 QPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTA----------TMDD-----------M 1200 Query: 930 PSPAPPPE 937 P PPPE Sbjct: 1201 ALPPPPPE 1208 Score = 56.2 bits (134), Expect = 1e-07 Identities = 96/393 (24%), Positives = 135/393 (34%), Gaps = 119/393 (30%) Query: 621 TGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLG 680 + + EA +RGT+ + + E+ N P SLV L +P+ Sbjct: 574 SSVFSEAWKRGTQLEESSKARMESMNRP---YTSLVPPLSPQPK---------------- 614 Query: 681 AEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAP--KPPSRG----- 733 + P T +P PPP P PPP P PPP P PS G Sbjct: 615 -----IVTPY------TASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPM 663 Query: 734 -----LLDGLVNGAASSAGI---PEPPRLQGRGGELFAKRQSRADRYVVEGTPGP----- 780 + L N + S + P PP +Q + K Q V P P Sbjct: 664 FVKYSTITRLQNASQHSGALFKPPTPPVMQSQS----VKPQILVPPNGVVPPPPPPPPPP 719 Query: 781 -------GLGPRPRSPS------PTPSL------------PPSWKYSPNIRA--PPPIAY 813 L P P +PS P P L PP+ P I A PP Sbjct: 720 TPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP 779 Query: 814 NPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTP-- 871 PL++ P + +T+ +Q TP + P K F +PP+P Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV---------PPAKKQPAFPASYIPPSPPT 830 Query: 872 -------------------GPIASGSPKTARVQEIRRFSTPAPQPTA---EPL--APTVL 907 P + SP + V++I P P P A +PL P + Sbjct: 831 PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANV 890 Query: 908 APRAATTLD-EPIWRTELASAPVPSPAPPPEAP 939 AP++ + +P W+ +S PVPSP PP P Sbjct: 891 APQSPPAVKAKPKWQP--SSIPVPSPDFPPPPP 921 Score = 43.5 bits (101), Expect = 0.001 Identities = 42/167 (25%), Positives = 62/167 (37%), Gaps = 25/167 (14%) Query: 84 VQRLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDS 143 V + A P P + Q P S + P PP PVP P P +L P +++ + Sbjct: 798 VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP--PPTL---PKQQSFCAKPPP 852 Query: 144 DADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPS 203 P ++ + P PTPP + P +P P P S + + P Sbjct: 853 SPLSPVPSVV-KQIASQFPPPPTPPA-------MESQPLKPVPANVAPQSPPAVK-AKPK 903 Query: 204 WEDGAAL-------QPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVA 243 W+ + PPP +L+ P P P +P P P P A Sbjct: 904 WQPSSIPVPSPDFPPPPPESSLVFP----PPPPSPVPAPPPPPPPTA 946 Score = 41.6 bits (96), Expect = 0.004 Identities = 48/198 (24%), Positives = 70/198 (35%), Gaps = 29/198 (14%) Query: 780 PGLGPRPR------SPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLP---- 829 P L P+P+ + P+P LPP P PPP PL S P A P Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666 Query: 830 -----KAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARV 884 + Q+ + M+ Q + + + VPP P P +P +A Sbjct: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA 726 Query: 885 QEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASA------PVPSPAPPPEA 938 Q PAP P P AP + + T++A P+P+P PP Sbjct: 727 Q-----LKPAP---CAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP 778 Query: 939 PRGLGASPSSCGFQVARP 956 P+ L P+ + P Sbjct: 779 PKPLVTIPAPTSTKTVAP 796 Score = 40.4 bits (93), Expect = 0.008 Identities = 40/166 (24%), Positives = 61/166 (36%), Gaps = 24/166 (14%) Query: 99 HELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSP------PDSEAYYGETDSDADGPA--- 149 H++Q ++ ++P +P PP P+P PL P + P P S + A P Sbjct: 750 HQVQHITQVAPPTPPPP-PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP 808 Query: 150 ----TQEKPRRPRRRGPTRPTPPGA-------PPDEVYLSDSPAEPAPTIPGPPSQGDSR 198 +++P P P P P P + + + P P +P Q S+ Sbjct: 809 PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ 868 Query: 199 VSSPSWEDGAALQP-PPAEALLLPHGP--LRPGPHLIPMVGPVPHP 241 P QP P A + P P ++ P P PVP P Sbjct: 869 FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSP 914 Score = 39.7 bits (91), Expect = 0.014 Identities = 36/124 (29%), Positives = 48/124 (38%), Gaps = 10/124 (8%) Query: 95 SPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSL----RSPPDSEAYYGETDSDADGPAT 150 SP P ++ ++ P P PP A QPL+P +SPP +A S P+ Sbjct: 856 SPVPSVVKQIASQFPPPPTPP-AMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSP 914 Query: 151 QEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAAL 210 P P P PP P A P P G P + S+ SSP + Sbjct: 915 DFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGK----- 969 Query: 211 QPPP 214 +PPP Sbjct: 970 KPPP 973 Score = 39.7 bits (91), Expect = 0.014 Identities = 49/178 (27%), Positives = 59/178 (33%), Gaps = 55/178 (30%) Query: 96 PSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPR 155 P P E ++ P P SP P P P P + PD G+ S P ++ P Sbjct: 918 PPPPESSLVFPPPPPSP----VPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973 Query: 156 RPRRRG------------PTRP---------TPP---GAPPDEVYLSDSPAEPAP----- 186 P+R P RP TPP G+P E L A P P Sbjct: 974 TPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKET-LPPPAAPPKPGKLNL 1032 Query: 187 ---TIPGPPSQG--------------DSRVSSPSWEDGAALQPPPAEALLLPHGPLRP 227 +PG QG DS V PS + PPP E L PL P Sbjct: 1033 SGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETEL----PLPP 1086 Score = 35.8 bits (81), Expect = 0.20 Identities = 52/224 (23%), Positives = 74/224 (33%), Gaps = 29/224 (12%) Query: 92 PVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQ 151 P SP P + + P P PP P P P P PP + + A P Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA-APMFV 665 Query: 152 EKPRRPRRRGPTR--------PTPP-----GAPPDEVYLSDSPAEPAPTIPGPPSQGDSR 198 + R + ++ PTPP P + + P P P PP+ G + Sbjct: 666 KYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAM 725 Query: 199 VS------SPSWEDGAALQPPPAEALLLPH-----GPLRPGPHLIPMVGP---VPHPVAE 244 +PS +A PPP + + H P P P IP P P P+ Sbjct: 726 AQLKPAPCAPSLPQFSA-PPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVT 784 Query: 245 DLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAP 288 T T+ Q A + AK + AS + +P Sbjct: 785 IPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSP 828 Score = 30.4 bits (67), Expect = 8.5 Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 4/66 (6%) Query: 127 SLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAP 186 S+ S SEA+ T + A E RP T PP +P ++ + ++P+P Sbjct: 571 SIVSSVFSEAWKRGTQLEESSKARMESMNRPY----TSLVPPLSPQPKIVTPYTASQPSP 626 Query: 187 TIPGPP 192 +P PP Sbjct: 627 PLPPPP 632 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 87.4 bits (215), Expect = 6e-17 Identities = 198/869 (22%), Positives = 281/869 (32%), Gaps = 222/869 (25%) Query: 59 VSCTNLSHASAMSLIDASGNQLVLTVQRLADEGPVQSPSPHELQVLSPLSPLSPEPPGAP 118 + T L H + L +L + GP++ +P L+V++ SP PEP A Sbjct: 584 IGITKLGHQKKLMLAVRKLAELQKAEYAKYEGGPLRRKAPQSLEVMAIESPPPPEPTPAD 643 Query: 119 VPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEK-------PRRPRRR----------- 160 P S E T GP T++ PR R+ Sbjct: 644 CQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHM 703 Query: 161 ---------GPTRPTPPGAPPDEVYLSDSPAE-------------------PAPTIPGPP 192 GP P+ P + E L + PA P +PG P Sbjct: 704 SSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKP 763 Query: 193 SQ----GDSRVSSPSWEDGAALQPPPAEALLLPHGP------LRPGPHLIPMV------- 235 Q G S + P + +P +AL PHGP ++P P L+P Sbjct: 764 RQVLPPGTSHFTPP--QTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPR 821 Query: 236 ----------------------------GPVPHPVAEDLTTTYTQKAKQAK----LQRAE 263 GP P PV + T A+ +RA Sbjct: 822 SLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAH 881 Query: 264 SLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEE 323 SL + +++ + + L+ AA P++ +RR GA + Sbjct: 882 SLNRYAASDSEPERDEL--LVPAAAGPYAT-----VQRRVGRSHSVRAPAGADKNVNRSQ 934 Query: 324 EDGVPPTSESELDE--EAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLS 381 V P + + S A + N +D P + E G RA + S L G + Sbjct: 935 SFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVD 994 Query: 382 EVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLP 441 S V+ AAML + RA PPE P+P P Sbjct: 995 TGSAGSVKSI-------------------AAMLELSSIGGGGRAARRPPEGH---PTPRP 1032 Query: 442 APVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG 501 A SP P G T S+ ++ A + +R T + + LA R G Sbjct: 1033 A---SPEP----GRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGP---G 1082 Query: 502 LSPAPPPFLSS-------QGPTPLPSFTSGVPSHAPVSGSPSTPR---------SSGPVT 545 S P PF+ +GP+ + G P A V S + R + Sbjct: 1083 ESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPL-AKVEASATLKRRIRAKQNQQENVKFI 1141 Query: 546 ATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPE 605 T S + + PEPP PP + T ++ + PE P P P A Sbjct: 1142 LTESDTVKRRPKAKEREAGPEPP-PPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEP 1200 Query: 606 PPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRA 665 PP+ +P EAR +P K SP P L V L P Sbjct: 1201 PPTDLAHLPPLPPPE----GEAR---------KPAKPPV--SPKPVLTQPVPKLQGSP-- 1243 Query: 666 GGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPP-PMAPKTPPPMTPK-TPP 723 + K +P P +P A TPPP++PK PP Sbjct: 1244 --------------------------TPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPP 1277 Query: 724 PVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLG 783 P APKP + GL +G+A + P P RQ A GTP P LG Sbjct: 1278 PTAPKPVK--AVAGLPSGSAGPSPAPSP------------ARQPPAALAKPPGTP-PSLG 1322 Query: 784 PRPRSPSPTPSLPPSWKYSPNIRAPPPIA 812 P P P+P P + ++ A PP A Sbjct: 1323 ASPAKP-PSPGAP-----ALHVPAKPPRA 1345 Score = 60.5 bits (145), Expect = 8e-09 Identities = 64/214 (29%), Positives = 89/214 (41%), Gaps = 23/214 (10%) Query: 422 PPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPT 481 PP A+ P + A LPP LP P R +P +P P + +P P LQG PT Sbjct: 1195 PPPAEPPPTDLAHLPP--LPPPEGEAR--KPAKPPVSPKPVL----TQP-VPKLQGS-PT 1244 Query: 482 TTSV---IFRPLAP--KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPS 536 TS + P +P KRA+ + +SP PPP P P+ + +G+PS GS Sbjct: 1245 PTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPP--PPTAPKPVKA-VAGLPS-----GSAG 1296 Query: 537 TPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEA 596 + P + P P + G +P P P A A+ A +A +A Sbjct: 1297 PSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAP 1356 Query: 597 PAPGPGAPEPPSAREQRISVPAARTGILQEARRR 630 PAP GA SAR++ A LQ + Sbjct: 1357 PAPPEGASPGDSARQKLEETSACLAAALQAVEEK 1390 Score = 54.3 bits (129), Expect = 5e-07 Identities = 124/599 (20%), Positives = 186/599 (31%), Gaps = 114/599 (19%) Query: 422 PPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPT 481 P + PP+ P + P P P P + + RP +P Q PT Sbjct: 769 PGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPT 828 Query: 482 TTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPR-- 539 + P PAPPP ++ LP P P + S R Sbjct: 829 HRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGR-PKKRAHSLNRYA 887 Query: 540 SSGPVTATSSLYIPAPSRPVTP-----GGAPEPPAPPSAAAMTSTASIFLSAPLRPSARP 594 +S L +PA + P G + AP A + + F P + P Sbjct: 888 ASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPP 947 Query: 595 EAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLS 654 P A + ++ + G+L R R+ G +T ++ + + ++ Sbjct: 948 PPPKRSSSALASANLADEPVPDAEPEDGLL--GVRAQCRRASDLAGSVDTGSAGSVKSIA 1005 Query: 655 LVQNLDEKPRAGGAESGPEE-------------------------DALSLGAEACNFMQP 689 + L G A P E +A+ G E N + Sbjct: 1006 AMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRT 1065 Query: 690 VGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIP 749 + L T + P + P P P+ PS+G AG+ Sbjct: 1066 LSGPVTGLL--ATARRGPGESAD-PGPFVEDGTGRQRPRGPSKG-----------EAGVE 1111 Query: 750 EPP------------RLQGRGGEL-----------FAKRQSRADRYVVEGTPGP------ 780 PP R++ + + KR+ +A P P Sbjct: 1112 GPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYH 1171 Query: 781 -GLGPRPRSPSPTPSLPPSWKYSPNIRAPPP--IAYNPLLSPFFPQAARTLPKAQSQGPR 837 G G R P+ + PP P PPP +A+ P L P P+ +++ P Sbjct: 1172 NGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPP---------PEGEARKPA 1222 Query: 838 ATPKQGIKALDFMRHQPY-QLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ 896 P L QP +L+ + + P PGP GSP+ R TP P Sbjct: 1223 KPPVSPKPVLT----QPVPKLQGSPTPTSKKVPLPGP---GSPEVKRAH-----GTPPPV 1270 Query: 897 PTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPA--------PPPEAPRGLGASPS 947 P PT P A + +P PSPA PP P LGASP+ Sbjct: 1271 SPKPPPPPTAPKPVKAVA---GLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPA 1326 Score = 34.7 bits (78), Expect = 0.45 Identities = 33/104 (31%), Positives = 38/104 (36%), Gaps = 16/104 (15%) Query: 106 PLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGP--ATQEKPRRPRRRG-- 161 P+SP P PP AP P G P A S A P A + P P G Sbjct: 1269 PVSPKPPPPPTAPKPVKAVAGL----PSGSAGPSPAPSPARQPPAALAKPPGTPPSLGAS 1324 Query: 162 PTRPTPPGAP--------PDEVYLSDSPAEPAPTIPGPPSQGDS 197 P +P PGAP P + + A P P S GDS Sbjct: 1325 PAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDS 1368 Score = 32.0 bits (71), Expect = 2.9 Identities = 56/231 (24%), Positives = 80/231 (34%), Gaps = 37/231 (16%) Query: 742 AASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPG-LGPRPRSPS----PTPSLP 796 A S PEP + ++ + S + GP +GP PS PTP Sbjct: 630 AIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRAT 689 Query: 797 PSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQS----QGPR-ATPKQGIKALDFMR 851 S RA + LL P + + ++Q +GP TP + + R Sbjct: 690 TRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARP---GR 746 Query: 852 HQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRA 911 H + +K A VPP PG + R+ P P PT P + Sbjct: 747 HG-HSIKRA-----SVPPVPG-------------KPRQVLPPGTSHFTPPQTPTKTRPGS 787 Query: 912 ATTLDEPIWRTELASAPVPSPA--PP---PEAPRGLGASPSSCGFQVARPR 957 L P + P+P PP P +PR L SP+ GF P+ Sbjct: 788 PQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQ 838 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 85.5 bits (210), Expect = 2e-16 Identities = 154/594 (25%), Positives = 207/594 (34%), Gaps = 111/594 (18%) Query: 394 QRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPG 453 +R RA + L R P+A + P ++ S+ E + PSP A+ R G Sbjct: 169 RRSRAAGTEVGLPRPAPSARPRPP-TEGPRKSVSSASEHSTTEPSP-----AARRRPSAG 222 Query: 454 GGAPTPAPSIFNRSARPFT-PGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSS 512 GG PA + SA P + P G T P AP + P P + Sbjct: 223 GGLQRPASRSLSSSATPLSSPARSGPSARGT-----PRAPAHPSQ------PKPKGLQAL 271 Query: 513 QGPTPLPSFTSGVPSHAPVSGSP-STPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 571 + P P P+ P+S SP +TP S P P+PS P + P PPA P Sbjct: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAP---------PSPSAPPSLQTLPSPPATP 322 Query: 572 SAAAMTS--------TASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGI 623 + A TS T S S PL P A P AP P PP + S PA+ Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP-PALALPP--LQAPPSPPAS---- 375 Query: 624 LQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQ---NLDEKPRAGGAESGPEEDALSLG 680 P + +PN + L+Q + P S P +S Sbjct: 376 -----------PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424 Query: 681 AEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVN 740 A + P A P PP P +PP TPPP AP P + L Sbjct: 425 ATPPSQAPPSLA--------APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476 Query: 741 GAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSP-SPTPSLPPSW 799 + + PP ++ P P ++P SP+ SLP S Sbjct: 477 PPQAPPALATPP---------------------LQALPSPPASFPGQAPFSPSASLPMSP 515 Query: 800 KYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKT 859 +P +APP +A L P P A+ TL Q PR P G D P +L Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTL-----QAPRRPPTPG---PDTSVSGP-RLTL 566 Query: 860 AMFCFDEVPPTPGPIAS---------GSPKTARVQEIRRF-STPAPQPTAEPLAPTVLAP 909 A+ PP+ P ++ S T+ +E+R + S P A P LA Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626 Query: 910 -RAATTLDEPIWRTELASAP-VPSPAPPPEAPRGLGASPSSCGFQVARPRFSAT 961 A P AP P P PP P G++ C SAT Sbjct: 627 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP---GSADGLCTIYETEGPESAT 677 Score = 84.7 bits (208), Expect = 4e-16 Identities = 198/778 (25%), Positives = 266/778 (34%), Gaps = 166/778 (21%) Query: 110 LSPEPPGAP-VPQPLQPGSLRSPPDSEAYYGETDSD-ADGPATQEKPRRPRRRGPTRPTP 167 L+P PPG+P P P+ P +LR + A + ++ A G P R GPTR + Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSR 84 Query: 168 PGAPPDEVYLSDSPAEPAP----TIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHG 223 P A E AP T PGP VSSP G Sbjct: 85 PPA--------SGRGERAPPAKNTSPGP-------VSSPGRASGTT-------------- 115 Query: 224 PLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASL 283 RPGP +G ++ + T + K + + +L + ++ Sbjct: 116 --RPGP-----LGQKGLRISAEETVA---RGKATEAPKRSALSAGARRD----------- 154 Query: 284 LTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDA 343 T+ P P + M ++ R AAGT E G+P + S Sbjct: 155 -TSGPTPGTPSPAMARRSR-------------AAGT----EVGLPRPAPSARPRPPTEGP 196 Query: 344 RSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLS-EVSGRGVQLFEQQRQRADSST 402 R + + S AR A G GL S +S L R + Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSA----GGGLQRPASRSLSSSATPLSSPARSGPSARG 252 Query: 403 QELARVEPAAMLNGEGLQ-------SPPRAQSAPPEAAVLPPSPL--PAPVASPRPFQPG 453 A P + +GLQ +PPR + A P L SPL P+P A P P P Sbjct: 253 TPRAPAHP-SQPKPKGLQALRPPQVTPPR-KDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 Query: 454 GGAPTPAPSIFNRSARPF---TPGLQGQRPTTTSVIFRPLA--PKRANDSLGGLSP--AP 506 P+P S +P LQ S PLA P +A +L L P AP Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL-ALPPLQAP 369 Query: 507 PPFLSSQGPTPLPSFTSGVPSHAPVS--GSPSTPRSSGPVTATSSLYIPAPSRPVTPGGA 564 P +S +PL + + P+ V +P +P S PV A S P S PV+P Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS---PPASPPVSPSAT 426 Query: 565 PEPPAPPSAAA--MTSTASIFLSAPLRPSARPEAPAPGP-GAPEPPSAREQRISVPAART 621 P APPS AA + S S P+ PSA P AP P AP A+ + PA T Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486 Query: 622 GILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGA 681 LQ + P S +L P A P Sbjct: 487 PPLQAL-------------PSPPASFPGQAPFSPSASLPMSPLATPPPQAP--------- 524 Query: 682 EACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP----------PPVAPKPPS 731 PV A +P P +P AP+ PP P T P P PPS Sbjct: 525 -------PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 577 Query: 732 R---GLLDG--LVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRP 786 R L G L ++S+ PE R G E A D + P Sbjct: 578 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW----S 633 Query: 787 RSPSPTPSLPPSWKYSPNIRAPPPIAYNP--------LLSPFFPQAARTLPKAQSQGP 836 R P+P P +++ +P P P A P + P++A P A GP Sbjct: 634 RGPAP----PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 687 Score = 80.5 bits (197), Expect = 7e-15 Identities = 133/552 (24%), Positives = 183/552 (33%), Gaps = 96/552 (17%) Query: 424 RAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTT 483 + A AA P+ + +PRP G+P P P P TP Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRP----PGSPRPPP--------PVTPAALRVLGAAG 51 Query: 484 SVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSS-G 542 +V +PLA + GG+ A P P P+ TS P+ +P +S G Sbjct: 52 AVGRKPLAERA-----GGIGGATIP---ESAPRAGPTRTSRPPASGRGERAPPAKNTSPG 103 Query: 543 PVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPG 602 PV++ P+ G A + A +T + SA L AR + P PG Sbjct: 104 PVSSPGRASGTTRPGPLGQKGL-RISAEETVARGKATEAPKRSA-LSAGARRDTSGPTPG 161 Query: 603 APEPPSAREQR-----ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQ 657 P P AR R + +P G RK + E + P+P Sbjct: 162 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV-SSASEHSTTEPSPA------ 214 Query: 658 NLDEKPRAGGAESGPEEDALSLGAEACNFMQPVG--ARSYKTLP-HVTPKTPPPMAPKTP 714 +P AGG P +LS A + G AR P H + P + P Sbjct: 215 -ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 273 Query: 715 PPMTP-----------------KTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGR 757 P +TP TP P AP PS S +P PP Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS---------APPSLQTLPSPPATP-- 322 Query: 758 GGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLL 817 + S + P P L P +P P PP+ P ++APP +P L Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSP---LATPPPQAPPALALPP-LQAPPSPPASPPL 378 Query: 818 SPF---FPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPI 874 SP PQA L Q P + P P Q + V P+ P Sbjct: 379 SPLATPSPQAPNALAVHLLQAPFSPPPS----------PPVQAPFSPPASPPVSPSATPP 428 Query: 875 ASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP 934 + P A P P + P++P+ P A LA+ P+ P Sbjct: 429 SQAPPSLAAPP----LQVPPSPPASPPMSPSATPPPQAP--------PPLAAPPLQLAKP 476 Query: 935 PPEAPRGLGASP 946 PP+AP L P Sbjct: 477 PPQAPPALATPP 488 Score = 47.0 bits (110), Expect = 9e-05 Identities = 72/273 (26%), Positives = 94/273 (34%), Gaps = 46/273 (16%) Query: 704 KTPPPMAPK--TP-PPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG-IPEPPRLQGRGG 759 +TP AP TP PP +P+ PPPV P V GAA + G P R G GG Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPVTPAALR-------VLGAAGAVGRKPLAERAGGIGG 67 Query: 760 ELFAKRQSRADRYVVEGTPGPGLGPR-PRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLS 818 + RA P G G R P + + +P S + P P+ L Sbjct: 68 ATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 127 Query: 819 PFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGS 878 AR KA R+ G + D PTP G+ Sbjct: 128 SAEETVAR--GKATEAPKRSALSAGARR------------------DTSGPTP-----GT 162 Query: 879 PKTARVQEIRRFST----PAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP 934 P A + R T P P P+A P PT ++ ++ E + P P+ Sbjct: 163 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE-----HSTTEPSPAARR 217 Query: 935 PPEAPRGLGASPSSCGFQVARPRFSATRTGLQA 967 P A GL S A P S R+G A Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250 Score = 47.0 bits (110), Expect = 9e-05 Identities = 50/159 (31%), Positives = 65/159 (40%), Gaps = 13/159 (8%) Query: 92 PVQSP-SPHELQVLSPLSPLSPEPPGAPVPQPLQ-PGSLRSPPDSEAYYGETDSDADGP- 148 P+Q+P SP LSPL+ SP+ P A LQ P S P +A + S P Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424 Query: 149 ATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGA 208 AT P P PP +PP +S S A P P P P + +++ P + Sbjct: 425 ATPPSQAPPSLAAPPLQVPP-SPPASPPMSPS-ATPPPQAPPPLAAPPLQLAKPPPQAPP 482 Query: 209 ALQPPPAEALLLP------HGPLRPGPHL--IPMVGPVP 239 AL PP +AL P P P L P+ P P Sbjct: 483 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 521 Score = 46.2 bits (108), Expect = 1e-04 Identities = 46/165 (27%), Positives = 64/165 (38%), Gaps = 26/165 (15%) Query: 88 ADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADG 147 A GP +P +P P P+P G +P Q +PP +A + A G Sbjct: 244 ARSGPSARGTPR-----APAHPSQPKPKGLQALRPPQV----TPPRKDA------APALG 288 Query: 148 PATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDG 207 P + P P+ P P APP L P+ PA PPSQ + + SP+ + Sbjct: 289 PLSSSPLATP---SPSAPPSPSAPPS---LQTLPSPPAT----PPSQATTSLGSPTLQAT 338 Query: 208 AALQP-PPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYT 251 + P PP L P P L P+ P P + L+ T Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 383 Score = 46.2 bits (108), Expect = 1e-04 Identities = 105/474 (22%), Positives = 145/474 (30%), Gaps = 66/474 (13%) Query: 96 PSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPR 155 P P LQ L P P AP PL L +P S S + P+ Q P Sbjct: 263 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP-----PSPSAPPSLQTLPS 317 Query: 156 RPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPA 215 P T G+P + S P+ P + PP Q ++ P LQ PP+ Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP------PLQAPPS 371 Query: 216 EALLLPHGPL-RPGP--------HLI----------PMVGPVPHPVAEDLTTTYTQKAKQ 256 P PL P P HL+ P+ P P + ++ + T ++ Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 431 Query: 257 AKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAA 316 A LQ A A+ AP P + L K +A A Sbjct: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--------PA 483 Query: 317 AGTGAEEEDGVPPTS---ESELDEEAFSDARSLTNQSDWDSPYLDMELAR------AGSR 367 T + PP S ++ A L P L L + A Sbjct: 484 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543 Query: 368 ASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQS-PPRAQ 426 + G + VSG + L S P++ L+G L A Sbjct: 544 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR------SPSSTLSGPDLAGHSSSAT 597 Query: 427 SAPPEAAVLPPSPLPAPVASPRP------FQPGGGAPTPAPSIFNRSA----RPFTPGLQ 476 S P E P ASP P P + PAP + R A P+ P Sbjct: 598 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 657 Query: 477 GQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAP 530 I+ P+ A + G L P P P + G +G S +P Sbjct: 658 PGSADGLCTIYETEGPESATPAPGALDPGPSP--GTSGGKAAAGAGAGASSRSP 709 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 81.6 bits (200), Expect = 3e-15 Identities = 106/436 (24%), Positives = 141/436 (32%), Gaps = 83/436 (19%) Query: 417 EGLQSPP-RAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGL 475 +G SPP + Q PP+ P P P P P GG P P +P P Sbjct: 48 QGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQGPPP 103 Query: 476 QGQRPTTTSVIFRPLAPKRANDSLGGLSP--APPPFLSSQGPTPLPSFTSGVPSHAPVSG 533 QG + + P + GG P PPP QGP P P P G Sbjct: 104 QGDKSRSPR---SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ---GGNKPQGPPPPG 157 Query: 534 SPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSAR 593 P P G + SS P + P G +P PP P + + Sbjct: 158 KPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ------GPPPQGGNK 211 Query: 594 PEAPAPGPGAPE-PPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPEL 652 P+ P P PG P+ PP + + + G Q +G + P P P+ Sbjct: 212 PQGPPP-PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ- 269 Query: 653 LSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK 712 N + P G GP G+++ + P G P+ PPP Sbjct: 270 ---GGNKPQGPPPPGKPQGPPPQG---GSKSRSSRSPPG----------KPQGPPPQGGN 313 Query: 713 -----TPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQS 767 PPP P+ PPP G G P P + QG + +K +S Sbjct: 314 QPQGPPPPPGKPQGPPP---------------QGGNKPQGPPPPGKPQGPPPQGGSKSRS 358 Query: 768 RADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAART 827 RSP P PP + + PPP N PQ + Sbjct: 359 ------------------ARSPPGKPQGPPQQEGNNPQGPPPPAGGN-------PQQPQA 393 Query: 828 LPKAQSQGPRATPKQG 843 P Q QGP P+ G Sbjct: 394 PPAGQPQGPPRPPQGG 409 Score = 65.1 bits (157), Expect = 3e-10 Identities = 104/428 (24%), Positives = 135/428 (31%), Gaps = 92/428 (21%) Query: 519 PSFTSGVPSHAPVSGS------PSTP------------RSSGPVTATSSLYIPAPSRPVT 560 PS +G P AP G PS P + GP P P Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88 Query: 561 PGGAPEPPAPPSAAAMTSTASIFLSAPLRPSA-------RPEAPAPGPGAPEPP----SA 609 P G P P P + S P +P +P+ P P PG P+ P Sbjct: 89 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 148 Query: 610 REQRISVPAARTGILQEARRRGTRKQMFRPGKEETK-----NSPNPELLSLVQNLDEKPR 664 + Q P G + + +R PGK + N P + P+ Sbjct: 149 KPQGPPPPGKPQGPPPQGDNK-SRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 207 Query: 665 AGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK-----TPPPMTP 719 G GP G + ARS P P+ PPP PPP P Sbjct: 208 GGNKPQGPPPPGKPQGPPPQGDNKSQSARS----PPGKPQGPPPQGGNQPQGPPPPPGKP 263 Query: 720 KTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQG---RGGELFAKRQSRADRYVVEG 776 + PPP G G P P + QG +GG R SR+ +G Sbjct: 264 QGPPP---------------QGGNKPQGPPPPGKPQGPPPQGGS--KSRSSRSPPGKPQG 306 Query: 777 TPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGP 836 P G G +P+ P P P P + PPP N P P + QGP Sbjct: 307 PPPQG-GNQPQGPPPPPGKP---------QGPPPQGGNKPQGP--------PPPGKPQGP 348 Query: 837 RATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ 896 P QG R P + + P P P A G+P+ + + PA Q Sbjct: 349 ---PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ-------APPAGQ 398 Query: 897 PTAEPLAP 904 P P P Sbjct: 399 PQGPPRPP 406 Score = 51.6 bits (122), Expect = 4e-06 Identities = 52/167 (31%), Positives = 64/167 (38%), Gaps = 18/167 (10%) Query: 70 MSLIDASGNQLVLTVQRLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQ--PLQPGS 127 M LI S L L+ + +E Q SP L +P P G PQ P PG Sbjct: 1 MLLILLSVALLALSSAQNLNEDVSQEESPS----LIAGNPQGAPPQGGNKPQGPPSPPGK 56 Query: 128 LRSPPDSEAYYGETDSDADGPATQEKPRRPRRRG---PTRPTPPG---APPDEVYLSDSP 181 + PP + P KP+ P +G P P PPG PP + S SP Sbjct: 57 PQGPPPQGG-----NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP 111 Query: 182 AEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPG 228 P GPP QG ++ P G PPP + P GP PG Sbjct: 112 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP-QGGNKPQGPPPPG 157 Score = 49.7 bits (117), Expect = 1e-05 Identities = 43/133 (32%), Positives = 55/133 (41%), Gaps = 14/133 (10%) Query: 109 PLSPEPPGAPVPQPLQPG----SLRSPPDS-EAYYGETDSDADGPATQE-KPRRPRRRG- 161 P P PPG P P Q S RSPP + + + GP KP+ P +G Sbjct: 150 PQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 209 Query: 162 --PTRPTPPGAPPDEVYLSDSPAEPAPTIPG----PPSQGDSRVSSPSWEDGAALQPPPA 215 P P PPG P D+ ++ A + PG PP QG ++ P G PPP Sbjct: 210 NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP- 268 Query: 216 EALLLPHGPLRPG 228 + P GP PG Sbjct: 269 QGGNKPQGPPPPG 281 Score = 48.9 bits (115), Expect = 2e-05 Identities = 42/132 (31%), Positives = 49/132 (37%), Gaps = 13/132 (9%) Query: 109 PLSPEPPGAPVPQPLQPGSL----RSPPDS-EAYYGETDSDADGPATQE-KPRRPRRRGP 162 P P PPG P P Q GS RSPP + + + GP KP+ P +G Sbjct: 274 PQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 333 Query: 163 TRPT-------PPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPA 215 +P P G PP S S P GPP Q + P G Q P A Sbjct: 334 NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 393 Query: 216 EALLLPHGPLRP 227 P GP RP Sbjct: 394 PPAGQPQGPPRP 405 Score = 46.6 bits (109), Expect = 1e-04 Identities = 46/143 (32%), Positives = 54/143 (37%), Gaps = 20/143 (13%) Query: 106 PLSPLSPEPPGAPVPQ-PLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRG--- 161 P P P P G PQ P PG + PP + D + KP+ P +G Sbjct: 75 PGKPQGPPPQGGNKPQGPPPPGKPQGPPP------QGDKSRSPRSPPGKPQGPPPQGGNQ 128 Query: 162 PTRPTPP-----GAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAE 216 P P PP G PP P P GPP QGD++ S G PPP + Sbjct: 129 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-QGPPPQGDNKSRSSRSPPGKPQGPPP-Q 186 Query: 217 ALLLPHGPLRPGPHLIPMVGPVP 239 P GP P P P GP P Sbjct: 187 GGNQPQGP--PPPPGKPQ-GPPP 206 Score = 44.7 bits (104), Expect = 4e-04 Identities = 46/143 (32%), Positives = 53/143 (37%), Gaps = 19/143 (13%) Query: 106 PLSPLSPEPPGAPVPQ-PLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRG--- 161 P P P P G PQ P PG + PP ++ G KP+ P +G Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPG-----KPQGPPPQGGNQ 252 Query: 162 PTRPTPP-----GAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAE 216 P P PP G PP P P GPP QG S+ S G PPP + Sbjct: 253 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-QGPPPQGGSKSRSSRSPPGKPQGPPP-Q 310 Query: 217 ALLLPHGPLRPGPHLIPMVGPVP 239 P GP P P P GP P Sbjct: 311 GGNQPQGP--PPPPGKPQ-GPPP 330 Score = 37.7 bits (86), Expect = 0.053 Identities = 36/124 (29%), Positives = 47/124 (37%), Gaps = 12/124 (9%) Query: 420 QSPP-RAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG- 477 +SPP + Q PP+ P P P P P GG P P +P P QG Sbjct: 298 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQGPPPQGG 353 Query: 478 -QRPTTTSVIFRPLAP--KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGS 534 + + S +P P + N+ G P PP + Q P P+ P P G Sbjct: 354 SKSRSARSPPGKPQGPPQQEGNNPQG---PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGR 410 Query: 535 PSTP 538 PS P Sbjct: 411 PSRP 414 >gi|149158690 HLA-B associated transcript-2 [Homo sapiens] Length = 2157 Score = 79.3 bits (194), Expect = 2e-14 Identities = 221/979 (22%), Positives = 315/979 (32%), Gaps = 175/979 (17%) Query: 97 SPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRR 156 +P + P +P P P P P P P L +PP A P + +P Sbjct: 499 APDKRLKAEPAAP--PAAPSTPAPPPAVPKELPAPP--------APPPASAPTPETEPEE 548 Query: 157 PRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAE 216 P + P + TP L + T G PS E P P E Sbjct: 549 PAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEG-----PEPPE 603 Query: 217 ALLLPHGPLRPGPHLIPM---VGPVPHPVAEDLTTTYTQKAKQAKLQRAES---LQEKSI 270 + P P P P + P +GP P ++ L QK+ + QR + L+++ Sbjct: 604 EVPPPTTP--PVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQ 661 Query: 271 KEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPT 330 + + + A P+P L Q + A G PP Sbjct: 662 HQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRP-------PPM 714 Query: 331 SESELDEE-----AFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSG 385 D + D R L + D + + +G E SG G SE Sbjct: 715 PPMNFDPRWMMIPPYVDPRLLQGRPPLD--FYPPGVHPSGLVPRERSDSG--GSSSEPFD 770 Query: 386 RGV--QLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAV---LPPSPL 440 R L E+ D + V A L SP R + + + PP P Sbjct: 771 RHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPP 830 Query: 441 PAPVASPRPFQPGGGAPTPAPSIF-----NRSARPFTPG------LQGQRP------TTT 483 P P + P P GAP P S F P+ PG +Q P T Sbjct: 831 PPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEET 890 Query: 484 SVIFRPLAPKRANDSLGGLSPAPPP------FLSSQGPTPLPSFTSGVPSHAPVSGSPST 537 + + P A ++ +G PPP + GP P S G+P P G+P Sbjct: 891 AQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRP-GSSRRGIPPEEP--GAP-- 945 Query: 538 PRSSGPV--TATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPE 595 PR +GP+ + P +P+ G E P PP + T + E Sbjct: 946 PRRAGPIKKPPPPTKVEELPPKPLEQG--DETPKPPKPDPLKITKG-------KLGGPKE 996 Query: 596 APAPGPGAPEPPSARE---QRISVPAARTGILQE--ARRRGTRKQMFRPGKEETKNSPNP 650 P G +P P R+ +R+ + R E AR RG R G + + + Sbjct: 997 TPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRG----RGARSR 1052 Query: 651 ELLSLVQNLDEKPRAGGAESGPEEDALSLG-------AEACNFMQPVGARSYKTLPHVTP 703 E S + + R GG GP G +E + + R + + Sbjct: 1053 EFRSYREFRGDDGRGGGT-GGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSE 1111 Query: 704 KTPPPMAPKTPPPMTPK----TPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGG 759 +AP TPK T P+AP PP GA S P P R RGG Sbjct: 1112 THESDLAPSDKEAPTPKEGTLTQVPLAPPPP----------GAPPS---PAPARFTARGG 1158 Query: 760 ELFAKRQSRADRYVVEGTPGPGLGP--RPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLL 817 +F R + R G P P + P P + S P PP+ P P + PL Sbjct: 1159 RVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPT--------GPLPPSKEPLK 1210 Query: 818 SPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASG 877 P + + S G + + RH Q + + PP + Sbjct: 1211 EKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQ-------DKPPRFRRLKQE 1263 Query: 878 SPKTARVQEIR-RFSTPAPQPTAEPLAPTVL---APRAATTLDEPI-----------WRT 922 AR E + + PA P E TV APR A + W T Sbjct: 1264 RENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWET 1323 Query: 923 ELASAPVPS------PAPPPE--APRGLGASPSSCGFQV------------------ARP 956 S+ S APPP P+ +G G V ++ Sbjct: 1324 ASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKR 1383 Query: 957 RFSATRTGLQAHVWRPGAG 975 FS+ R G++ RPG G Sbjct: 1384 SFSSQRPGMERQNRRPGPG 1402 Score = 71.6 bits (174), Expect = 3e-12 Identities = 141/563 (25%), Positives = 188/563 (33%), Gaps = 91/563 (16%) Query: 418 GLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG 477 GLQ P PP ++PP P + P P+ P G P P +R R P G Sbjct: 234 GLQ-PSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSG 292 Query: 478 QRPTTTSVIFRPLAPKRAN------------DSLGGLSPA---PPPFLSSQGPTPLPSFT 522 + RP K N D G S S Sbjct: 293 PPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDE 352 Query: 523 SGVPSHAP---VSGSPSTPRSSG------------PVTATSSLYIPAPSRPVTPGGAPEP 567 G H SG P + G P TA + P + P P AP+P Sbjct: 353 EGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPP--APKP 410 Query: 568 PAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEA 627 P PP P R + PAP E + R++R + + ++ A Sbjct: 411 PLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAP---EDEDEAWRQRRKQSSSEISLAVERA 467 Query: 628 RRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM 687 RRR R++ R +EE + + +L + LDEK A E A Sbjct: 468 RRR--REEEERRMQEERRAACAEKL----KRLDEKFGAPDKRLKAEPAA----------- 510 Query: 688 QPVGARSYKTLPHVTPKTPPPMAPKTPPPM---TPKTPPPV-APKPPSRGLLDGLVNGAA 743 P A S P PK P AP PPP TP+T P A PP++ + Sbjct: 511 -PPAAPSTPAPPPAVPKELP--APPAPPPASAPTPETEPEEPAQAPPAQ---------ST 558 Query: 744 SSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSP 803 + G+ P L GG + + VE GP P P P+ PP K P Sbjct: 559 PTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEP 618 Query: 804 NIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFC 863 P P +P+ ++LP + R +Q +K + Q +Q +A Sbjct: 619 KGDGIGPTRQPPSQGLGYPKYQKSLP---PRFQRQQQEQLLKQQQQHQWQQHQQGSA--- 672 Query: 864 FDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTE 923 PPTP P + P T + PAPQ A P P L P A L P Sbjct: 673 ----PPTPVPPSPPQPVTLG-------AVPAPQ--APPPPPKALYPGA---LGRPPPMPP 716 Query: 924 LASAPVPSPAPPPEAPRGLGASP 946 + P PP PR L P Sbjct: 717 MNFDPRWMMIPPYVDPRLLQGRP 739 Score = 63.9 bits (154), Expect = 7e-10 Identities = 220/979 (22%), Positives = 304/979 (31%), Gaps = 240/979 (24%) Query: 133 DSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPP 192 DS+ E D+ + +E+P P G +P PP + P T PGPP Sbjct: 349 DSDEEGAEGHRDSQSASGEERP--PEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPP 406 Query: 193 SQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQ 252 + P A PP + P R GP P P ED + Q Sbjct: 407 APKPPL--PPPHRGPAGNWGPPGDY------PDRGGP-------PCKPPAPEDEDEAWRQ 451 Query: 253 KAKQAKLQ----------RAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRR 302 + KQ+ + R E + + +E + C L K + + Sbjct: 452 RRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDK-----RLKA 506 Query: 303 QRAKKYTLVSFGAAAGTGAEEEDGVP-------PTSESELDEEAFSD-ARSLTNQSDWDS 354 + A S A +E P PT E+E +E A + A+S + Sbjct: 507 EPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAA 566 Query: 355 PYLDMELARAGSRASEGQGS----GLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEP 410 P L ++ GS +S GS + QL G E + +T + +VEP Sbjct: 567 PTL---VSGGGSTSSTSSGSFEASPVEPQLPSKEGP-----EPPEEVPPPTTPPVPKVEP 618 Query: 411 AAMLNG-------EGLQSPPRAQSAPP----------------------EAAVLPPSPLP 441 G +GL P +S PP + PP+P+P Sbjct: 619 KGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVP 678 Query: 442 APVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRP----LAPKRAND 497 P P QP PAP + PG G+ P + F P + P Sbjct: 679 -----PSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPR 733 Query: 498 SLGGLSPAP--PPFLSSQGPTPLPSFTSGVPS------HAPV----SGSP---------- 535 L G P PP + G P SG S HAP G+P Sbjct: 734 LLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVG 793 Query: 536 ----STPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPS 591 +TP P+T+ + + P PP PP A+ AP P Sbjct: 794 DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPE--NGAPGPPI 851 Query: 592 ARPEAPAPGP-GAPEPPSARE-QRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN 649 +R PGP P PP + E +I P + P KEET Sbjct: 852 SRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKK----------------EPPKEETAQLTG 895 Query: 650 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPP-- 707 PE KP G G + P S + +P P PP Sbjct: 896 PE-------AGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRR 948 Query: 708 --PMAPKTPPPMTPKTPP---------PVAPKPPSRGLLDGLVNG---AASSAGIPEPPR 753 P+ PP + PP P PKP + G + G + + PR Sbjct: 949 AGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPR 1008 Query: 754 L--------------QGRG-GELFAK-----------------------RQSRADRYVVE 775 L +GRG GE FA+ R+ R D Sbjct: 1009 LRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGG 1068 Query: 776 GTPGPGLGPRP--RSPSPTPSLPPSWKYSPNIR-----APPPIAYNPLLSPFFPQAARTL 828 GT GP P P R+ S T S ++ P R + L+P +A Sbjct: 1069 GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPK 1128 Query: 829 PKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGP---IASG----SPKT 881 +Q P A P G PP+P P A G +P+ Sbjct: 1129 EGTLTQVPLAPPPPG-----------------------APPSPAPARFTARGGRVFTPRG 1165 Query: 882 ARVQEIRRFSTPAPQ--PTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAP 939 + R P PQ P P A + LAP+ T P + L +P P P Sbjct: 1166 VPSRRGRGGGRPPPQVCPGWSPPAKS-LAPKKPPTGPLPPSKEPLKEKLIPGPLSP--VA 1222 Query: 940 RGLGASPSSCGFQVA-RPR 957 RG S+ G + RPR Sbjct: 1223 RGGSNGGSNVGMEDGERPR 1241 Score = 61.6 bits (148), Expect = 3e-09 Identities = 204/921 (22%), Positives = 287/921 (31%), Gaps = 186/921 (20%) Query: 106 PLSPLSPEPPGAPVPQPLQPGS-----LRSPPDSEAYYGETDSDADGPATQEKPRRPRRR 160 P+S E PG P P P PGS +++PP + E + GP KP R Sbjct: 850 PISRFPLEEPG-PRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGS 908 Query: 161 GPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLL 220 G P PP E P G SR P E GA PP A Sbjct: 909 GGQGPPPPRR------------ESRTETRWGPRPGSSRRGIPPEEPGA----PPRRA--- 949 Query: 221 PHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTI 280 GP++ P + P P+ + T K K+ + + K Sbjct: 950 --GPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKE----------- 996 Query: 281 ASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAF 340 PN G L R +R Y V + G G E Sbjct: 997 -----TPPN----GNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRG- 1046 Query: 341 SDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADS 400 ARS +S Y + R +G+G G GG + RG E + + ++ Sbjct: 1047 RGARSREFRS-----YREF-------RGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEY 1094 Query: 401 STQELARVEPAAMLNGEGLQSP--PRAQSAP-PEAAVLPPSPLPAPVASPRPFQPGGGAP 457 R + + E +S P + AP P+ L PL P P G P Sbjct: 1095 EEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPP--------PPGAPP 1146 Query: 458 TPAPSIFN-RSARPFTP-------GLQGQRPTTT-----SVIFRPLAPKRANDSLGGLSP 504 +PAP+ F R R FTP G G RP S + LAPK+ G L P Sbjct: 1147 SPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKP--PTGPLPP 1204 Query: 505 APPPFLSSQGPTPLPSFTSGVPS-----------------HAPVSGSPSTPR-------- 539 + P P PL G + H PR Sbjct: 1205 SKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQER 1264 Query: 540 ------SSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTAS------------ 581 S G + T P P +T PAP AAA + S Sbjct: 1265 ENAARGSEGKPSLTLPASAPGPEEALTT--VTVAPAPRRAAAKSPDLSNQNSDQANEEWE 1322 Query: 582 -IFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPG 640 S+ R + AP P P + A GI A RG Q + Sbjct: 1323 TASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGI--SAMSRGDLSQRAKDL 1380 Query: 641 KEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPH 700 + + +S P + + + +P GG ++G + G G ++ P Sbjct: 1381 SKRSFSSQRPGM----ERQNRRPGPGG-KAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPS 1435 Query: 701 VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEP-PRLQGRGG 759 ++ PP + PP P PPP + R LD +++ ++ AGI + +L R G Sbjct: 1436 PKNRSRPP---EERPPGLPLPPPPPSSSAVFR--LDQVIH--SNPAGIQQALAQLSSRQG 1488 Query: 760 ELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSP 819 + A + PGL P+ PSP P P P + P Sbjct: 1489 SVTAPGGHPRHK--------PGLPQAPQGPSPRP---------PTRYEPQRVNSGLSSDP 1531 Query: 820 FFPQAARTLPKAQSQGPRATPKQ--GIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASG 877 F + P +G TP+ G+ R + K + + +PP G Sbjct: 1532 HFEE-----PGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLG 1586 Query: 878 SPKTARVQEIRRFSTPAPQPTAEPLAPTVLAP----RAATTLDEPIWRTELASAPVPSPA 933 S P PQ + L P R T +R + P P Sbjct: 1587 SKPEG----------PGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPS-SMEPWMEPL 1635 Query: 934 PPPEAPRGLGASPSSCGFQVA 954 P E G S S G ++ Sbjct: 1636 SPFEDVAGTEMSQSDSGVDLS 1656 Score = 55.5 bits (132), Expect = 2e-07 Identities = 226/1057 (21%), Positives = 324/1057 (30%), Gaps = 215/1057 (20%) Query: 97 SPHELQVLSPLSPLSPE---PPGAPVPQPLQP-----GSLRSPPDSEAYYGETDSDADG- 147 SP E Q+ S P PE PP P ++P G R PP Y + Sbjct: 587 SPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPR 646 Query: 148 ----------PATQEKPRRPRRRGPTRPTP-PGAPPDEVYLSDSPAEPAPTIPG----PP 192 Q+ + ++G PTP P +PP V L PA AP P P Sbjct: 647 FQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPG 706 Query: 193 SQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHP---VAEDLTTT 249 + G P D + PP L G RP P P HP V + + + Sbjct: 707 ALGRPPPMPPMNFDPRWMMIPPYVDPRLLQG--RPPLDFYP---PGVHPSGLVPRERSDS 761 Query: 250 YTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAP--------------NPHSKGV 295 ++ L+E+ K + + TA P + KG+ Sbjct: 762 GGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGM 821 Query: 296 LMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEA---------FSDARSL 346 Y L S+ GA PP S L+E + + Sbjct: 822 RSETPPVPPPPPY-LASYPGFPENGAPG----PPISRFPLEEPGPRPLPWPPGSDEVAKI 876 Query: 347 TNQSDWDSPYLDMELARAGSRASE--GQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQE 404 P + G A +G G GGQ R + + R SS + Sbjct: 877 QTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRG 936 Query: 405 LARVEPAAMLNGEG-LQSPP---RAQSAPP------EAAVLPPSPLPAPVAS-----PRP 449 + EP A G ++ PP + + PP + PP P P + P+ Sbjct: 937 IPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKE 996 Query: 450 FQPGGGAPTPAPSI---------------------FNRSARPFTPGLQGQRPTTTSVIFR 488 P G +PAP + + R F G+ S FR Sbjct: 997 TPPNGNL-SPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFR 1055 Query: 489 PLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSG-----VPSHAPVSGSPSTPRSSGP 543 R +D GG + P + +G T + + G +P GS + + Sbjct: 1056 SYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHES 1115 Query: 544 VTATSSLYIPAPSRPV---TPGGAPEPPAPPSAAAMTSTAS---IFL--SAPLR------ 589 A S P P P P P APPS A TA +F P R Sbjct: 1116 DLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGG 1175 Query: 590 -----------PSARPEAPAPGPGAPEPPSAREQRISV------PAARTGI---LQEARR 629 P A+ AP P P PPS + + P AR G Sbjct: 1176 RPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGME 1235 Query: 630 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQP 689 G R + R G+ + ++ P P L Q + R G+E P +L+L A A + Sbjct: 1236 DGERPRRRRHGRAQQQDKP-PRFRRLKQERENAAR--GSEGKP---SLTLPASAPGPEEA 1289 Query: 690 VGARSYKTLPHVTPKTPPPMAPKTPPPMTPK-------------------TPPPVAPKPP 730 + + P P ++ + + PPPV P Sbjct: 1290 LTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPK 1349 Query: 731 SRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVE--------------- 775 + G G GA L R +L +KR + R +E Sbjct: 1350 AVGTPGGGGGGAVPGISAMSRGDLSQRAKDL-SKRSFSSQRPGMERQNRRPGPGGKAGSS 1408 Query: 776 ------------GTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFF-- 821 G GPG G + PSP P + P + PPP P S F Sbjct: 1409 GSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPP---PPSSSAVFRL 1465 Query: 822 PQAARTLPKAQSQG-PRATPKQGIKAL--DFMRHQPYQLKTAMFCFDEVPPTPGPIASGS 878 Q + P Q + + +QG RH+P + P+P P Sbjct: 1466 DQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQ------GPSPRPPTRYE 1519 Query: 879 PK--TARVQEIRRFSTPAPQPT---AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPA 933 P+ + + F P P P ++P + P + EL Sbjct: 1520 PQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQ---EESL 1576 Query: 934 PPPEAPRGLGASPSSCGFQVARPRFSATRTGLQAHVW 970 PPP + LG+ P G Q A R + T L H+W Sbjct: 1577 PPPHSSGFLGSKPEGPGPQ-AESRDTGTE-ALTPHIW 1611 Score = 53.5 bits (127), Expect = 9e-07 Identities = 173/758 (22%), Positives = 235/758 (31%), Gaps = 176/758 (23%) Query: 94 QSPSPHELQVLSPLSPLSPEPPGAP--------------------VPQPLQPGSLRSPPD 133 ++P+P E + PL+P PPGAP VP G R PP Sbjct: 1123 EAPTPKEGTLTQV--PLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPP- 1179 Query: 134 SEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPS 193 + PA P++P PT P PP P + L P P + S Sbjct: 1180 ------QVCPGWSPPAKSLAPKKP----PTGPLPPSKEPLKEKLIPGPLSP---VARGGS 1226 Query: 194 QGDSRVSSPSWE------DGAALQ---PPPAEALLLPHGPLRPG----PHL-IPMVGPVP 239 G S V E G A Q PP L G P L +P P P Sbjct: 1227 NGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGP 1286 Query: 240 HPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFK 299 E LTT A + ++ L ++ +A + TA+ + Sbjct: 1287 E---EALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWE------TASESSDFTSERRGD 1337 Query: 300 KRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFS-DARSLTNQSDWDSPYLD 358 K T + G G G G+ S +L + A RS ++Q P ++ Sbjct: 1338 KEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQ----RPGME 1393 Query: 359 MELARAG--------SRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEP 410 + R G +S G G G GG+ GRG +R+ S + +R P Sbjct: 1394 RQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG--PGRG-------DKRSWPSPKNRSR-PP 1443 Query: 411 AAMLNGEGLQSPPRAQSAPPEA-AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSAR 469 G L PP + SA V+ +P A + G P ++ Sbjct: 1444 EERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGL 1503 Query: 470 PFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHA 529 P P RP T P+R N L + P GP Sbjct: 1504 PQAPQGPSPRPPTR------YEPQRVNSGL-----SSDPHFEEPGPM------------- 1539 Query: 530 PVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLR 589 V G TPR S V+ P P PP P S S L Sbjct: 1540 -VRGVGGTPRDSAGVS------------PFPPKRRERPPRKPELLQEESLPPPHSSGFL- 1585 Query: 590 PSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN 649 ++PE P P E R + A T + T ++ +RP E P Sbjct: 1586 -GSKPEGPGP---------QAESRDTGTEALTPHIWNRLHTATSRKSYRPSSME----PW 1631 Query: 650 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARS-----YKTLPHVTPK 704 E LS +++ G E + + L ++ P RS K PK Sbjct: 1632 MEPLSPFEDV------AGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPK 1685 Query: 705 TPPPMAP------KTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRG 758 P +P + PP P PP AP R L P PP Sbjct: 1686 RPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKEL---------PREQPLPP------ 1730 Query: 759 GELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLP 796 G + +R R DR G P P PS P P Sbjct: 1731 GPIGTERSQRTDR---------GTEPGPIRPSHRPGPP 1759 Score = 51.6 bits (122), Expect = 4e-06 Identities = 148/644 (22%), Positives = 197/644 (30%), Gaps = 159/644 (24%) Query: 420 QSPPRAQSA----PPEAAVLPPSPLPA------PVASPR--PFQPGG------------- 454 QS P++ A PPE+ LP S PA P A+P P P G Sbjct: 92 QSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGA 151 Query: 455 -GAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSS- 512 G A S+ +R +R P LQ + R A + G P+ P S+ Sbjct: 152 HGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESA-----EQSSGPGPSLRPQNSTT 206 Query: 513 ------QGPTPLPSFTSGV-PSHAPVSG-SPSTPRSSGPVTATSSLYIPAPSRPVTPGGA 564 +GP L S + H P G PS P P ++ P P P Sbjct: 207 WRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYG 266 Query: 565 PEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAP-GPGAPEPPSAREQRISVPAARTGI 623 P+ P P PS P P G G P R+ P R I Sbjct: 267 PQGP-------------YRYPTPDGPSRFPRVAGPRGSGPP-------MRLVEPVGRPSI 306 Query: 624 LQE-------------------ARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPR 664 L+E A + + EE + E + + Sbjct: 307 LKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEE---GAEGHRDSQS 363 Query: 665 AGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPP-------- 716 A G E PE D + P A + + P T PP P PPP Sbjct: 364 ASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNW 423 Query: 717 -----MTPKTPPPVAPKPPSRGLLDGLVNGAASSAGI------------PEPPRLQGRGG 759 + PP P P SS+ I E R+Q Sbjct: 424 GPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERR 483 Query: 760 ELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSP 819 A++ R D G P L P +P PS P APPP L +P Sbjct: 484 AACAEKLKRLDEKF--GAPDKRLKAEPAAPPAAPSTP----------APPPAVPKELPAP 531 Query: 820 FFPQAA-----RTLPKAQSQGP--RATPKQGIKALDFM---------------RHQPYQ- 856 P A T P+ +Q P ++TP G+ A + P + Sbjct: 532 PAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEP 591 Query: 857 ---LKTAMFCFDEV-PPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAA 912 K +EV PPT P+ PK + R+ P Q P L PR Sbjct: 592 QLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQ---PPSQGLGYPKYQKSLPPRFQ 648 Query: 913 TTLDEPI--------WRTELASAPVPSPAPP-PEAPRGLGASPS 947 E + W+ + P+P PP P P LGA P+ Sbjct: 649 RQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPA 692 Score = 36.6 bits (83), Expect = 0.12 Identities = 111/457 (24%), Positives = 148/457 (32%), Gaps = 104/457 (22%) Query: 125 PGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEP 184 P S RS PD G A+GP P+RP P P PP S+ P P Sbjct: 1665 PCSQRSSPD-----GGLKGAAEGP-----PKRPGGSSPLNAVPCEGPPG----SEPPRRP 1710 Query: 185 APTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPH-------GPLRPGPHLIPMVGP 237 P P GD R P + L P P GP+RP P V Sbjct: 1711 PPA----PHDGD-RKELPREQP---LPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQF 1762 Query: 238 VPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPN--PHSK-- 293 DL K AE S+ EA R L +AA + P SK Sbjct: 1763 GTSDKDSDLRLVVGDSLK------AEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNL 1816 Query: 294 --GVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSD 351 G + + + Y V +G+A + ++ G +D + ++ + Sbjct: 1817 DSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGA-------MDSQLHPNSGGFRPGTP 1869 Query: 352 WDSPYLDMELARAGSRASEG---QGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARV 408 PY L A G L GQ + S EL ++ Sbjct: 1870 SLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFS--------------TMQATELGKL 1915 Query: 409 EPAAMLNGEG--LQSPPRAQSAPPEAAVLPP-SPLPAPVAS-PRPFQPGGGA---PTPAP 461 +L L SP S P+ ++L LP+P P QPGG + P+ AP Sbjct: 1916 PAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAP 1975 Query: 462 SIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSF 521 + + P + Q P + G L PAPPP P PL Sbjct: 1976 A-----QQMLLPMVDSQLPVV---------------NFGSLPPAPPP-----APPPLSLL 2010 Query: 522 TSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRP 558 G P PS P AT L P+P+RP Sbjct: 2011 PVG-----PALQPPSLAVRPPPAPATRVL--PSPARP 2040 Score = 34.3 bits (77), Expect = 0.59 Identities = 64/297 (21%), Positives = 90/297 (30%), Gaps = 71/297 (23%) Query: 85 QRLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPP------------ 132 Q A PV P + + + +P +P PP P+ L PG+L PP Sbjct: 669 QGSAPPTPVPPSPPQPVTLGAVPAPQAPPPP----PKALYPGALGRPPPMPPMNFDPRWM 724 Query: 133 ------DSEAYYGETDSDADGPATQEKPRRPRRRGPT------------------RPTPP 168 D G D P PR R + R TPP Sbjct: 725 MIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPP 784 Query: 169 GAPPDEVYLSD----SPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGP 224 P ++ D +PAEP P + P Q + + PPP P P Sbjct: 785 -VDPKLAWVGDVFTATPAEPRP-LTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFP 842 Query: 225 LR--PGPHLI------PMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTK 276 PGP + P P+P P D + + + E+ Q + + Sbjct: 843 ENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKP 902 Query: 277 CRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAE----EEDGVPP 329 R + S P P R + T +G G+ EE G PP Sbjct: 903 ARGVGSGGQGPPPP-------------RRESRTETRWGPRPGSSRRGIPPEEPGAPP 946 Score = 33.1 bits (74), Expect = 1.3 Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 16/112 (14%) Query: 422 PPRAQSAPPEAAVLPPSP-LPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP 480 PP APP ++LP P L P + RP P PA + ARPF L R Sbjct: 1997 PPAPPPAPPPLSLLPVGPALQPPSLAVRP------PPAPATRVLPSPARPFPASL--GRA 2048 Query: 481 TTTSVIFRPLAP-KRANDSLG--GLSPAPPPFLSSQGPT----PLPSFTSGV 525 V +P ++ + +LG G S PP S G PS SGV Sbjct: 2049 ELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGV 2100 Score = 32.3 bits (72), Expect = 2.2 Identities = 64/261 (24%), Positives = 91/261 (34%), Gaps = 49/261 (18%) Query: 490 LAPKRANDSLGGLS-------PAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSG 542 +AP+ SLG ++ PA P L ++ P+ S VP +G S S Sbjct: 38 VAPRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPN-VSLVPKDG--TGWASKQEQSD 94 Query: 543 PVTATSSLYIPAPSRPVTPGGAP---EPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAP 599 P ++ +S P S+P+ P +P PP+A T + + + S A Sbjct: 95 PKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGD 154 Query: 600 GPGAPEPPSAREQRISVPAARTGILQE--ARRRGTRKQMFRPGKEETKNSPNPELLSLVQ 657 G G +R R P + Q+ A+ R + +Q PG SL Sbjct: 155 G-GRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGP------------SLRP 201 Query: 658 NLDEKPRAGGAESGPEE-----DALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK 712 R GG GP+E L G + +QP G PP P Sbjct: 202 QNSTTWRDGGGR-GPDELEGPDSKLHHGHDPRGGLQPSG---------------PPQFPP 245 Query: 713 TPPPMTPKTPPPVAPKPPSRG 733 M P PP P PP G Sbjct: 246 YRGMMPPFMYPPYLPFPPPYG 266 Score = 30.8 bits (68), Expect = 6.5 Identities = 38/162 (23%), Positives = 54/162 (33%), Gaps = 18/162 (11%) Query: 88 ADEGPVQSPSPHELQVL-SPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDAD 146 +D Q P L +P S PP AP PL P ++S + +G A Sbjct: 98 SDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHG-----AH 152 Query: 147 GPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWED 206 G + R PT A + + + + PGP + +S +W D Sbjct: 153 GDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQ---NSTTWRD 209 Query: 207 GAALQPPPAEALLL-------PHGPLRPG--PHLIPMVGPVP 239 G P E P G L+P P P G +P Sbjct: 210 GGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMP 251 >gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 79.0 bits (193), Expect = 2e-14 Identities = 107/395 (27%), Positives = 131/395 (33%), Gaps = 103/395 (26%) Query: 436 PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRA 495 PP P PAP +P GG+P P+P S P P L Sbjct: 141 PPPPGPAPGPPQDISEPPGGSPLPSPP----STAPPPPPLL------------------- 177 Query: 496 NDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAP 555 L P PPP S P P P + P H SPS P + L AP Sbjct: 178 ------LEPPPPP---SMAPPPPPVLEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAP 226 Query: 556 SRPVTPGGAPEPPAPP------------------SAAAMTSTASIFLSAPLRPSARPEAP 597 P P AP PA P A A ++P R A P+ Sbjct: 227 PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGS 286 Query: 598 APGPGAPEPPSAREQRISVP---AARTGIL--QEARRRGTRKQMFRPGKEETKNSPNPEL 652 A GP PEP + VP RT + QEA+ P KEE P Sbjct: 287 ALGPN-PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQE--------APRKEEGATKKAPSR 337 Query: 653 LSLVQNLDEKPRAG-GAESGPEEDAL-SLGAEACNFMQPVGARSYKTLPHVTPK--TPPP 708 L L + +P + + PE D L A A P R ++ + TPPP Sbjct: 338 LPLPPSFHIRPASQVYPDRAPEPDCPGELKATA-----PASPRLGQSQSQADERAGTPPP 392 Query: 709 MAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSR 768 AP PPP P PPP P PP+ L A AG + P+ Sbjct: 393 -APPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPK--------------- 435 Query: 769 ADRYVVEGTPGPGLGPRPRSPSP---TPSLPPSWK 800 + P L P+P PSP S P W+ Sbjct: 436 --------SSSPALKPKPNPPSPENTASSAPVDWR 462 Score = 75.5 bits (184), Expect = 2e-13 Identities = 155/618 (25%), Positives = 211/618 (34%), Gaps = 130/618 (21%) Query: 405 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIF 464 L + P L+ + +PP P A L P P P P +P P PA S Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAP---------PAPA-SPH 243 Query: 465 NRSARPFTPG----------LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFL---- 510 R F PG L G++ T P +P S L P P P L Sbjct: 244 TVGTRLFPPGGVTKWKSDVALNGRQAEATRA-SPPRSPAEPKGS--ALGPNPEPHLTFPR 300 Query: 511 SSQGPTPLPSFTSGVP----SHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPE 566 S + P P P TS +P AP +T ++ + S +I P+ V P APE Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI-RPASQVYPDRAPE 359 Query: 567 PPAPPSAAAMTSTASIFLS-------------APLRPSARPEAPAPGPGAPEPPSAREQR 613 P P A T+ AS L P P P P P P P PP+A Sbjct: 360 PDCPGELKA-TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAP--- 415 Query: 614 ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPE 673 +P A+ A T K P + N P+PE + +D + S E Sbjct: 416 -PLPCAQKAAHPPAGFTKTPKSS-SPALKPKPNPPSPENTASSAPVDWRD-----PSQME 468 Query: 674 EDALSLGAEACNFMQPVGARSYKTLPHVTPKTPP----PMAPK-----------TPPPMT 718 + L A C + S++ P V P++ P P+ TPP + Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528 Query: 719 PKT----------------------PPPVAPKPPSRGL---LDGLVNGAASSAGIPE--- 750 K+ P +P P R + L+ ++ AA P Sbjct: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588 Query: 751 -PPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPP 809 PP+ + GG + ++ AD + L P+ + PT SL P P I PP Sbjct: 589 LPPKPRLEGGRIC---ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI--PP 643 Query: 810 PIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 869 P + P T PKA + GP ATP LK + Sbjct: 644 KATPEPAIPPKATLWPATPPKA-TLGP-ATP----------------LKATSGPTTPLKA 685 Query: 870 TPGP----IASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELA 925 T GP A+ P T + S PA QP +P + V P A P T L Sbjct: 686 TSGPAIASTATTLPTTTSQLMAEKDSGPAGQP-EKPASQEVSTPSQARGEGSPSEATRLP 744 Query: 926 SAPVPSPA--PPPEAPRG 941 + S A PP +P G Sbjct: 745 TQGARSSAAFPPKTSPGG 762 Score = 62.8 bits (151), Expect = 2e-09 Identities = 233/986 (23%), Positives = 315/986 (31%), Gaps = 275/986 (27%) Query: 84 VQRLADEGPVQSPS----PHELQVLSPLSPLSPEPPGAPVPQPLQPGS------------ 127 ++ L+ + SPS P + PL+ L+P PP P P P P S Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPG 253 Query: 128 -------------------LRSPPDSEAYYGETDSDADGP-------------------- 148 SPP S A E A GP Sbjct: 254 GVTKWKSDVALNGRQAEATRASPPRSPA---EPKGSALGPNPEPHLTFPRSFKVPPPTPV 310 Query: 149 --------ATQEKPRRPR---RRGPTR-PTPPG---APPDEVYLS-----DSPAEPAPTI 188 QE PR+ ++ P+R P PP P +VY D P E T Sbjct: 311 RTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATA 370 Query: 189 PGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPL-RPGPHLIPMVGPVP------HP 241 P P G S+ S D A PPPA L P PL P P L P P+P HP Sbjct: 371 PASPRLGQSQ----SQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426 Query: 242 VAEDLTTTYTQKAKQAKLQ-------------------RAESLQEKSIKE-AKTKC--RT 279 A T T K+ L+ R S EK E A C R Sbjct: 427 PA---GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483 Query: 280 IASLLTAAPNPH-SKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEE 338 L+ P P + KK + +K TL+S A + GVP S Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA-----KDTPPGVPEKSLGGSSLT 538 Query: 339 AFSDARSLTNQS----DWDSP---------YLDMELARAGSRASEGQGSGL-------GG 378 A SLT S DSP L+ L+ A + ++ L GG Sbjct: 539 ETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGG 598 Query: 379 QLSEVSGRGVQLFEQQRQRADSSTQEL---ARVEPAAMLNGEGLQSPPRA---QSAPPEA 432 ++ E +L + + + L ++P AML G PP+A + PP+A Sbjct: 599 RICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAML---GPAIPPKATPEPAIPPKA 655 Query: 433 AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 492 + P +P A + P + G TP ++ P PTTTS + +A Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTP----LKATSGPAIASTATTLPTTTSQL---MAE 708 Query: 493 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHA---PVSGSPST----PRSSGPVT 545 K + G + P S + TP + G PS A P G+ S+ P++S Sbjct: 709 KDS-----GPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGG 763 Query: 546 ATSSLYIP------------------------APSRPVTPGGAPEPPAPPSAAAMT---- 577 LY P P PV P PA P A+A Sbjct: 764 EVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDEL 823 Query: 578 -------------STASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGIL 624 S ++ L+A R A + P S R+ A+ I Sbjct: 824 LRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIF 883 Query: 625 QEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEAC 684 + + + KE K+SP E P G G + + L + Sbjct: 884 HSQGTPNSFTVVPKLPKEAEKDSP---------LTTEIPNKWGPRLGRDAEGTEL-SRRH 933 Query: 685 NFMQPVG---------ARSYKTLPHVTPK---TPPPMAPK-------------TPPPMTP 719 N+ +P A S H PK +PP + K PPP Sbjct: 934 NWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFS 993 Query: 720 KTPPPVAP---------KPPSRGLLD--GLVN---GAASSAGIPEPP------------R 753 P P AP PP D L N GA + G P R Sbjct: 994 NDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLER 1053 Query: 754 LQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPS---PTPSLPPSWKYSPNIRAPPP 810 G G L KR + + G P G G SP+ P P P + + RAPP Sbjct: 1054 FSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPG 1113 Query: 811 IAYNPLLSPFFPQAARTLPKAQSQGP 836 + P LS AAR +A+ + P Sbjct: 1114 GLHAPRLS--LEGAARGAAEAKHKAP 1137 Score = 52.4 bits (124), Expect = 2e-06 Identities = 75/297 (25%), Positives = 103/297 (34%), Gaps = 53/297 (17%) Query: 699 PHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGL-VNGAASSAGIPEPPRLQGR 757 P +P PP PPP+ + PPP + PP +L+ L SS IP PP Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPP----- 212 Query: 758 GGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLP-PSWKYSPNIRAPPP------ 810 ++ P L P P P P P+ P P+ ++ R PP Sbjct: 213 -------------DFIPPAPPLAFLAP-PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258 Query: 811 ---IAYN---PLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCF 864 +A N + P + PK + GP P F P ++T+ Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR-SFKVPPPTPVRTSSIPV 317 Query: 865 DEVPPTPGPIASGSPKTARVQ-------EIRRFSTPAPQPTAEPLAPTVL------APRA 911 E P G+ K A + IR S P EP P L +PR Sbjct: 318 QEAQEAPRK-EEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376 Query: 912 ATTLDEPIWR--TELASAPVPSPA---PPPEAPRGLGASPSSCGFQVARPRFSATRT 963 + + R T + P+P PA PPP P A P C + A P T+T Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKT 433 Score = 43.1 bits (100), Expect = 0.001 Identities = 54/187 (28%), Positives = 68/187 (36%), Gaps = 28/187 (14%) Query: 96 PSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPR 155 P P P +S P G+P+P P P + PP S A P + Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSP--PSTAPPPPPLLLEPPPPPSMAPPPPPVLEAL 197 Query: 156 RPRR--RGPTRPTPPG----APPDEVYLSDSPAEPAPTIPGP--PSQGDSRVSSP----S 203 P P+ PTPP APP P PAP P P P +R+ P Sbjct: 198 SPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTK 257 Query: 204 WEDGAAL----------QPP--PAEALLLPHGPLRPGPHL-IPMVGPVPHPVAEDLTTTY 250 W+ AL PP PAE GP P PHL P VP P ++ Sbjct: 258 WKSDVALNGRQAEATRASPPRSPAEPKGSALGP-NPEPHLTFPRSFKVPPPTPVRTSSIP 316 Query: 251 TQKAKQA 257 Q+A++A Sbjct: 317 VQEAQEA 323 Score = 41.6 bits (96), Expect = 0.004 Identities = 128/548 (23%), Positives = 174/548 (31%), Gaps = 136/548 (24%) Query: 464 FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTS 523 FN + T L+ + + F PL + N L +P+ P + + T S + Sbjct: 58 FNTVSESGTATLKARPRVRPLLTFLPLNAQE-NHGLAVPTPSVPDDFADKEVTGTSSLVN 116 Query: 524 GVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIF 583 G + + S R P L IP P PG + PP + + S S Sbjct: 117 G---NLRLYSSVGDLR---PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS-- 168 Query: 584 LSAPLRPSARPEAPAPGPGAPEPPSAREQRI----------------------------- 614 +AP P E P P AP PP E Sbjct: 169 -TAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP 227 Query: 615 --SVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGP 672 VPA GTR +F PG S ++L E RA S Sbjct: 228 PPPVPAPAPPAPASPHTVGTR--LFPPGGVTKWKSD----VALNGRQAEATRASPPRSPA 281 Query: 673 EEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPP-PVAPKPPS 731 E +LG P+ P P + K PPP +T PV + Sbjct: 282 EPKGSALG------------------PNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323 Query: 732 RGLLDGLVNGAASSAGIPEPPRLQGR-GGELFAKRQSRAD---RYVVEGTPGPGLG---- 783 +G A S +P PP R +++ R D P LG Sbjct: 324 PRKEEGATKKAPSR--LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381 Query: 784 ---PRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQS-----QG 835 R +P P P LPP P PPP +P P AA LP AQ G Sbjct: 382 QADERAGTPPPAPPLPP-----PAPPLPPP-------APPLPPAAPPLPCAQKAAHPPAG 429 Query: 836 PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSP----KTARVQEIR--- 888 TPK AL + +P PP+P AS +P ++++++R Sbjct: 430 FTKTPKSSSPAL---KPKPN------------PPSPENTASSAPVDWRDPSQMEKLRNEL 474 Query: 889 -----------RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPE 937 RF + P PT +AP + L E + L S P PP Sbjct: 475 AAYLCGSRREDRFLSHRPGPT---VAPQSKEGKKGPRLPE---KETLLSLPA-KDTPPGV 527 Query: 938 APRGLGAS 945 + LG S Sbjct: 528 PEKSLGGS 535 Score = 36.2 bits (82), Expect = 0.15 Identities = 98/421 (23%), Positives = 136/421 (32%), Gaps = 77/421 (18%) Query: 28 RKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHASAMSLIDASGNQLVLTVQRL 87 R P Q+ K+R A G R D+ LSH TV Sbjct: 462 RDPSQMEKLRNELAAYLCGSRREDRF----------LSHRPGP------------TVAPQ 499 Query: 88 ADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADG 147 + EG P + +LS P PPG VP+ GS S ++EA T D Sbjct: 500 SKEGKKGPRLPEKETLLS--LPAKDTPPG--VPEKSLGGS--SLTETEAAPSLTLPSVDY 553 Query: 148 -PATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPG----PPSQGDSRVSSP 202 P P + R A E S P P + G D ++S P Sbjct: 554 IPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKP 613 Query: 203 SWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGP--VPHPVAEDLTTTYTQKAKQAKLQ 260 A PP LLP L+P L P + P P P T + +A L Sbjct: 614 -----VAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLG 668 Query: 261 RAESLQEKSIKEAKTKCRT---IASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAA 317 A L+ S K + IAS T P S+ LM Sbjct: 669 PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQ--LM-------------------- 706 Query: 318 GTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLG 377 AE++ G E +E + +++ S ++ L + AR+ S A + S G Sbjct: 707 ---AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARS-SAAFPPKTSPGG 762 Query: 378 GQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPP 437 G+ V + S ++E+A V P G P PP PP Sbjct: 763 GE--------VPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPP 814 Query: 438 S 438 + Sbjct: 815 A 815 >gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 79.0 bits (193), Expect = 2e-14 Identities = 107/395 (27%), Positives = 131/395 (33%), Gaps = 103/395 (26%) Query: 436 PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRA 495 PP P PAP +P GG+P P+P S P P L Sbjct: 141 PPPPGPAPGPPQDISEPPGGSPLPSPP----STAPPPPPLL------------------- 177 Query: 496 NDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAP 555 L P PPP S P P P + P H SPS P + L AP Sbjct: 178 ------LEPPPPP---SMAPPPPPVLEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAP 226 Query: 556 SRPVTPGGAPEPPAPP------------------SAAAMTSTASIFLSAPLRPSARPEAP 597 P P AP PA P A A ++P R A P+ Sbjct: 227 PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGS 286 Query: 598 APGPGAPEPPSAREQRISVP---AARTGIL--QEARRRGTRKQMFRPGKEETKNSPNPEL 652 A GP PEP + VP RT + QEA+ P KEE P Sbjct: 287 ALGPN-PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQE--------APRKEEGATKKAPSR 337 Query: 653 LSLVQNLDEKPRAG-GAESGPEEDAL-SLGAEACNFMQPVGARSYKTLPHVTPK--TPPP 708 L L + +P + + PE D L A A P R ++ + TPPP Sbjct: 338 LPLPPSFHIRPASQVYPDRAPEPDCPGELKATA-----PASPRLGQSQSQADERAGTPPP 392 Query: 709 MAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSR 768 AP PPP P PPP P PP+ L A AG + P+ Sbjct: 393 -APPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPK--------------- 435 Query: 769 ADRYVVEGTPGPGLGPRPRSPSP---TPSLPPSWK 800 + P L P+P PSP S P W+ Sbjct: 436 --------SSSPALKPKPNPPSPENTASSAPVDWR 462 Score = 75.5 bits (184), Expect = 2e-13 Identities = 155/618 (25%), Positives = 211/618 (34%), Gaps = 130/618 (21%) Query: 405 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIF 464 L + P L+ + +PP P A L P P P P +P P PA S Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAP---------PAPA-SPH 243 Query: 465 NRSARPFTPG----------LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFL---- 510 R F PG L G++ T P +P S L P P P L Sbjct: 244 TVGTRLFPPGGVTKWKSDVALNGRQAEATRA-SPPRSPAEPKGS--ALGPNPEPHLTFPR 300 Query: 511 SSQGPTPLPSFTSGVP----SHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPE 566 S + P P P TS +P AP +T ++ + S +I P+ V P APE Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI-RPASQVYPDRAPE 359 Query: 567 PPAPPSAAAMTSTASIFLS-------------APLRPSARPEAPAPGPGAPEPPSAREQR 613 P P A T+ AS L P P P P P P P PP+A Sbjct: 360 PDCPGELKA-TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAP--- 415 Query: 614 ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPE 673 +P A+ A T K P + N P+PE + +D + S E Sbjct: 416 -PLPCAQKAAHPPAGFTKTPKSS-SPALKPKPNPPSPENTASSAPVDWRD-----PSQME 468 Query: 674 EDALSLGAEACNFMQPVGARSYKTLPHVTPKTPP----PMAPK-----------TPPPMT 718 + L A C + S++ P V P++ P P+ TPP + Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528 Query: 719 PKT----------------------PPPVAPKPPSRGL---LDGLVNGAASSAGIPE--- 750 K+ P +P P R + L+ ++ AA P Sbjct: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588 Query: 751 -PPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPP 809 PP+ + GG + ++ AD + L P+ + PT SL P P I PP Sbjct: 589 LPPKPRLEGGRIC---ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI--PP 643 Query: 810 PIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 869 P + P T PKA + GP ATP LK + Sbjct: 644 KATPEPAIPPKATLWPATPPKA-TLGP-ATP----------------LKATSGPTTPLKA 685 Query: 870 TPGP----IASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELA 925 T GP A+ P T + S PA QP +P + V P A P T L Sbjct: 686 TSGPAIASTATTLPTTTSQLMAEKDSGPAGQP-EKPASQEVSTPSQARGEGSPSEATRLP 744 Query: 926 SAPVPSPA--PPPEAPRG 941 + S A PP +P G Sbjct: 745 TQGARSSAAFPPKTSPGG 762 Score = 62.8 bits (151), Expect = 2e-09 Identities = 233/986 (23%), Positives = 315/986 (31%), Gaps = 275/986 (27%) Query: 84 VQRLADEGPVQSPS----PHELQVLSPLSPLSPEPPGAPVPQPLQPGS------------ 127 ++ L+ + SPS P + PL+ L+P PP P P P P S Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPG 253 Query: 128 -------------------LRSPPDSEAYYGETDSDADGP-------------------- 148 SPP S A E A GP Sbjct: 254 GVTKWKSDVALNGRQAEATRASPPRSPA---EPKGSALGPNPEPHLTFPRSFKVPPPTPV 310 Query: 149 --------ATQEKPRRPR---RRGPTR-PTPPG---APPDEVYLS-----DSPAEPAPTI 188 QE PR+ ++ P+R P PP P +VY D P E T Sbjct: 311 RTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATA 370 Query: 189 PGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPL-RPGPHLIPMVGPVP------HP 241 P P G S+ S D A PPPA L P PL P P L P P+P HP Sbjct: 371 PASPRLGQSQ----SQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426 Query: 242 VAEDLTTTYTQKAKQAKLQ-------------------RAESLQEKSIKE-AKTKC--RT 279 A T T K+ L+ R S EK E A C R Sbjct: 427 PA---GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483 Query: 280 IASLLTAAPNPH-SKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEE 338 L+ P P + KK + +K TL+S A + GVP S Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA-----KDTPPGVPEKSLGGSSLT 538 Query: 339 AFSDARSLTNQS----DWDSP---------YLDMELARAGSRASEGQGSGL-------GG 378 A SLT S DSP L+ L+ A + ++ L GG Sbjct: 539 ETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGG 598 Query: 379 QLSEVSGRGVQLFEQQRQRADSSTQEL---ARVEPAAMLNGEGLQSPPRA---QSAPPEA 432 ++ E +L + + + L ++P AML G PP+A + PP+A Sbjct: 599 RICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAML---GPAIPPKATPEPAIPPKA 655 Query: 433 AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 492 + P +P A + P + G TP ++ P PTTTS + +A Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTP----LKATSGPAIASTATTLPTTTSQL---MAE 708 Query: 493 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHA---PVSGSPST----PRSSGPVT 545 K + G + P S + TP + G PS A P G+ S+ P++S Sbjct: 709 KDS-----GPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGG 763 Query: 546 ATSSLYIP------------------------APSRPVTPGGAPEPPAPPSAAAMT---- 577 LY P P PV P PA P A+A Sbjct: 764 EVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDEL 823 Query: 578 -------------STASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGIL 624 S ++ L+A R A + P S R+ A+ I Sbjct: 824 LRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIF 883 Query: 625 QEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEAC 684 + + + KE K+SP E P G G + + L + Sbjct: 884 HSQGTPNSFTVVPKLPKEAEKDSP---------LTTEIPNKWGPRLGRDAEGTEL-SRRH 933 Query: 685 NFMQPVG---------ARSYKTLPHVTPK---TPPPMAPK-------------TPPPMTP 719 N+ +P A S H PK +PP + K PPP Sbjct: 934 NWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFS 993 Query: 720 KTPPPVAP---------KPPSRGLLD--GLVN---GAASSAGIPEPP------------R 753 P P AP PP D L N GA + G P R Sbjct: 994 NDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLER 1053 Query: 754 LQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPS---PTPSLPPSWKYSPNIRAPPP 810 G G L KR + + G P G G SP+ P P P + + RAPP Sbjct: 1054 FSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPG 1113 Query: 811 IAYNPLLSPFFPQAARTLPKAQSQGP 836 + P LS AAR +A+ + P Sbjct: 1114 GLHAPRLS--LEGAARGAAEAKHKAP 1137 Score = 52.4 bits (124), Expect = 2e-06 Identities = 75/297 (25%), Positives = 103/297 (34%), Gaps = 53/297 (17%) Query: 699 PHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGL-VNGAASSAGIPEPPRLQGR 757 P +P PP PPP+ + PPP + PP +L+ L SS IP PP Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPP----- 212 Query: 758 GGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLP-PSWKYSPNIRAPPP------ 810 ++ P L P P P P P+ P P+ ++ R PP Sbjct: 213 -------------DFIPPAPPLAFLAP-PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258 Query: 811 ---IAYN---PLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCF 864 +A N + P + PK + GP P F P ++T+ Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR-SFKVPPPTPVRTSSIPV 317 Query: 865 DEVPPTPGPIASGSPKTARVQ-------EIRRFSTPAPQPTAEPLAPTVL------APRA 911 E P G+ K A + IR S P EP P L +PR Sbjct: 318 QEAQEAPRK-EEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376 Query: 912 ATTLDEPIWR--TELASAPVPSPA---PPPEAPRGLGASPSSCGFQVARPRFSATRT 963 + + R T + P+P PA PPP P A P C + A P T+T Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKT 433 Score = 43.1 bits (100), Expect = 0.001 Identities = 54/187 (28%), Positives = 68/187 (36%), Gaps = 28/187 (14%) Query: 96 PSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPR 155 P P P +S P G+P+P P P + PP S A P + Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSP--PSTAPPPPPLLLEPPPPPSMAPPPPPVLEAL 197 Query: 156 RPRR--RGPTRPTPPG----APPDEVYLSDSPAEPAPTIPGP--PSQGDSRVSSP----S 203 P P+ PTPP APP P PAP P P P +R+ P Sbjct: 198 SPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTK 257 Query: 204 WEDGAAL----------QPP--PAEALLLPHGPLRPGPHL-IPMVGPVPHPVAEDLTTTY 250 W+ AL PP PAE GP P PHL P VP P ++ Sbjct: 258 WKSDVALNGRQAEATRASPPRSPAEPKGSALGP-NPEPHLTFPRSFKVPPPTPVRTSSIP 316 Query: 251 TQKAKQA 257 Q+A++A Sbjct: 317 VQEAQEA 323 Score = 41.6 bits (96), Expect = 0.004 Identities = 128/548 (23%), Positives = 174/548 (31%), Gaps = 136/548 (24%) Query: 464 FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTS 523 FN + T L+ + + F PL + N L +P+ P + + T S + Sbjct: 58 FNTVSESGTATLKARPRVRPLLTFLPLNAQE-NHGLAVPTPSVPDDFADKEVTGTSSLVN 116 Query: 524 GVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIF 583 G + + S R P L IP P PG + PP + + S S Sbjct: 117 G---NLRLYSSVGDLR---PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS-- 168 Query: 584 LSAPLRPSARPEAPAPGPGAPEPPSAREQRI----------------------------- 614 +AP P E P P AP PP E Sbjct: 169 -TAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP 227 Query: 615 --SVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGP 672 VPA GTR +F PG S ++L E RA S Sbjct: 228 PPPVPAPAPPAPASPHTVGTR--LFPPGGVTKWKSD----VALNGRQAEATRASPPRSPA 281 Query: 673 EEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPP-PVAPKPPS 731 E +LG P+ P P + K PPP +T PV + Sbjct: 282 EPKGSALG------------------PNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323 Query: 732 RGLLDGLVNGAASSAGIPEPPRLQGR-GGELFAKRQSRAD---RYVVEGTPGPGLG---- 783 +G A S +P PP R +++ R D P LG Sbjct: 324 PRKEEGATKKAPSR--LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381 Query: 784 ---PRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQS-----QG 835 R +P P P LPP P PPP +P P AA LP AQ G Sbjct: 382 QADERAGTPPPAPPLPP-----PAPPLPPP-------APPLPPAAPPLPCAQKAAHPPAG 429 Query: 836 PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSP----KTARVQEIR--- 888 TPK AL + +P PP+P AS +P ++++++R Sbjct: 430 FTKTPKSSSPAL---KPKPN------------PPSPENTASSAPVDWRDPSQMEKLRNEL 474 Query: 889 -----------RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPE 937 RF + P PT +AP + L E + L S P PP Sbjct: 475 AAYLCGSRREDRFLSHRPGPT---VAPQSKEGKKGPRLPE---KETLLSLPA-KDTPPGV 527 Query: 938 APRGLGAS 945 + LG S Sbjct: 528 PEKSLGGS 535 Score = 36.2 bits (82), Expect = 0.15 Identities = 98/421 (23%), Positives = 136/421 (32%), Gaps = 77/421 (18%) Query: 28 RKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHASAMSLIDASGNQLVLTVQRL 87 R P Q+ K+R A G R D+ LSH TV Sbjct: 462 RDPSQMEKLRNELAAYLCGSRREDRF----------LSHRPGP------------TVAPQ 499 Query: 88 ADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADG 147 + EG P + +LS P PPG VP+ GS S ++EA T D Sbjct: 500 SKEGKKGPRLPEKETLLS--LPAKDTPPG--VPEKSLGGS--SLTETEAAPSLTLPSVDY 553 Query: 148 -PATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPG----PPSQGDSRVSSP 202 P P + R A E S P P + G D ++S P Sbjct: 554 IPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKP 613 Query: 203 SWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGP--VPHPVAEDLTTTYTQKAKQAKLQ 260 A PP LLP L+P L P + P P P T + +A L Sbjct: 614 -----VAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLG 668 Query: 261 RAESLQEKSIKEAKTKCRT---IASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAA 317 A L+ S K + IAS T P S+ LM Sbjct: 669 PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQ--LM-------------------- 706 Query: 318 GTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLG 377 AE++ G E +E + +++ S ++ L + AR+ S A + S G Sbjct: 707 ---AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARS-SAAFPPKTSPGG 762 Query: 378 GQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPP 437 G+ V + S ++E+A V P G P PP PP Sbjct: 763 GE--------VPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPP 814 Query: 438 S 438 + Sbjct: 815 A 815 >gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens] Length = 1188 Score = 79.0 bits (193), Expect = 2e-14 Identities = 107/395 (27%), Positives = 131/395 (33%), Gaps = 103/395 (26%) Query: 436 PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRA 495 PP P PAP +P GG+P P+P S P P L Sbjct: 141 PPPPGPAPGPPQDISEPPGGSPLPSPP----STAPPPPPLL------------------- 177 Query: 496 NDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAP 555 L P PPP S P P P + P H SPS P + L AP Sbjct: 178 ------LEPPPPP---SMAPPPPPVLEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAP 226 Query: 556 SRPVTPGGAPEPPAPP------------------SAAAMTSTASIFLSAPLRPSARPEAP 597 P P AP PA P A A ++P R A P+ Sbjct: 227 PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGS 286 Query: 598 APGPGAPEPPSAREQRISVP---AARTGIL--QEARRRGTRKQMFRPGKEETKNSPNPEL 652 A GP PEP + VP RT + QEA+ P KEE P Sbjct: 287 ALGPN-PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQE--------APRKEEGATKKAPSR 337 Query: 653 LSLVQNLDEKPRAG-GAESGPEEDAL-SLGAEACNFMQPVGARSYKTLPHVTPK--TPPP 708 L L + +P + + PE D L A A P R ++ + TPPP Sbjct: 338 LPLPPSFHIRPASQVYPDRAPEPDCPGELKATA-----PASPRLGQSQSQADERAGTPPP 392 Query: 709 MAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSR 768 AP PPP P PPP P PP+ L A AG + P+ Sbjct: 393 -APPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPK--------------- 435 Query: 769 ADRYVVEGTPGPGLGPRPRSPSP---TPSLPPSWK 800 + P L P+P PSP S P W+ Sbjct: 436 --------SSSPALKPKPNPPSPENTASSAPVDWR 462 Score = 75.5 bits (184), Expect = 2e-13 Identities = 155/618 (25%), Positives = 211/618 (34%), Gaps = 130/618 (21%) Query: 405 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIF 464 L + P L+ + +PP P A L P P P P +P P PA S Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAP---------PAPA-SPH 243 Query: 465 NRSARPFTPG----------LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFL---- 510 R F PG L G++ T P +P S L P P P L Sbjct: 244 TVGTRLFPPGGVTKWKSDVALNGRQAEATRA-SPPRSPAEPKGS--ALGPNPEPHLTFPR 300 Query: 511 SSQGPTPLPSFTSGVP----SHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPE 566 S + P P P TS +P AP +T ++ + S +I P+ V P APE Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI-RPASQVYPDRAPE 359 Query: 567 PPAPPSAAAMTSTASIFLS-------------APLRPSARPEAPAPGPGAPEPPSAREQR 613 P P A T+ AS L P P P P P P P PP+A Sbjct: 360 PDCPGELKA-TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAP--- 415 Query: 614 ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPE 673 +P A+ A T K P + N P+PE + +D + S E Sbjct: 416 -PLPCAQKAAHPPAGFTKTPKSS-SPALKPKPNPPSPENTASSAPVDWRD-----PSQME 468 Query: 674 EDALSLGAEACNFMQPVGARSYKTLPHVTPKTPP----PMAPK-----------TPPPMT 718 + L A C + S++ P V P++ P P+ TPP + Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528 Query: 719 PKT----------------------PPPVAPKPPSRGL---LDGLVNGAASSAGIPE--- 750 K+ P +P P R + L+ ++ AA P Sbjct: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588 Query: 751 -PPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPP 809 PP+ + GG + ++ AD + L P+ + PT SL P P I PP Sbjct: 589 LPPKPRLEGGRIC---ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI--PP 643 Query: 810 PIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 869 P + P T PKA + GP ATP LK + Sbjct: 644 KATPEPAIPPKATLWPATPPKA-TLGP-ATP----------------LKATSGPTTPLKA 685 Query: 870 TPGP----IASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELA 925 T GP A+ P T + S PA QP +P + V P A P T L Sbjct: 686 TSGPAIASTATTLPTTTSQLMAEKDSGPAGQP-EKPASQEVSTPSQARGEGSPSEATRLP 744 Query: 926 SAPVPSPA--PPPEAPRG 941 + S A PP +P G Sbjct: 745 TQGARSSAAFPPKTSPGG 762 Score = 62.8 bits (151), Expect = 2e-09 Identities = 233/986 (23%), Positives = 315/986 (31%), Gaps = 275/986 (27%) Query: 84 VQRLADEGPVQSPS----PHELQVLSPLSPLSPEPPGAPVPQPLQPGS------------ 127 ++ L+ + SPS P + PL+ L+P PP P P P P S Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPG 253 Query: 128 -------------------LRSPPDSEAYYGETDSDADGP-------------------- 148 SPP S A E A GP Sbjct: 254 GVTKWKSDVALNGRQAEATRASPPRSPA---EPKGSALGPNPEPHLTFPRSFKVPPPTPV 310 Query: 149 --------ATQEKPRRPR---RRGPTR-PTPPG---APPDEVYLS-----DSPAEPAPTI 188 QE PR+ ++ P+R P PP P +VY D P E T Sbjct: 311 RTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATA 370 Query: 189 PGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPL-RPGPHLIPMVGPVP------HP 241 P P G S+ S D A PPPA L P PL P P L P P+P HP Sbjct: 371 PASPRLGQSQ----SQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426 Query: 242 VAEDLTTTYTQKAKQAKLQ-------------------RAESLQEKSIKE-AKTKC--RT 279 A T T K+ L+ R S EK E A C R Sbjct: 427 PA---GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483 Query: 280 IASLLTAAPNPH-SKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEE 338 L+ P P + KK + +K TL+S A + GVP S Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA-----KDTPPGVPEKSLGGSSLT 538 Query: 339 AFSDARSLTNQS----DWDSP---------YLDMELARAGSRASEGQGSGL-------GG 378 A SLT S DSP L+ L+ A + ++ L GG Sbjct: 539 ETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGG 598 Query: 379 QLSEVSGRGVQLFEQQRQRADSSTQEL---ARVEPAAMLNGEGLQSPPRA---QSAPPEA 432 ++ E +L + + + L ++P AML G PP+A + PP+A Sbjct: 599 RICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAML---GPAIPPKATPEPAIPPKA 655 Query: 433 AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 492 + P +P A + P + G TP ++ P PTTTS + +A Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTP----LKATSGPAIASTATTLPTTTSQL---MAE 708 Query: 493 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHA---PVSGSPST----PRSSGPVT 545 K + G + P S + TP + G PS A P G+ S+ P++S Sbjct: 709 KDS-----GPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGG 763 Query: 546 ATSSLYIP------------------------APSRPVTPGGAPEPPAPPSAAAMT---- 577 LY P P PV P PA P A+A Sbjct: 764 EVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDEL 823 Query: 578 -------------STASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGIL 624 S ++ L+A R A + P S R+ A+ I Sbjct: 824 LRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIF 883 Query: 625 QEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEAC 684 + + + KE K+SP E P G G + + L + Sbjct: 884 HSQGTPNSFTVVPKLPKEAEKDSP---------LTTEIPNKWGPRLGRDAEGTEL-SRRH 933 Query: 685 NFMQPVG---------ARSYKTLPHVTPK---TPPPMAPK-------------TPPPMTP 719 N+ +P A S H PK +PP + K PPP Sbjct: 934 NWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFS 993 Query: 720 KTPPPVAP---------KPPSRGLLD--GLVN---GAASSAGIPEPP------------R 753 P P AP PP D L N GA + G P R Sbjct: 994 NDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLER 1053 Query: 754 LQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPS---PTPSLPPSWKYSPNIRAPPP 810 G G L KR + + G P G G SP+ P P P + + RAPP Sbjct: 1054 FSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPG 1113 Query: 811 IAYNPLLSPFFPQAARTLPKAQSQGP 836 + P LS AAR +A+ + P Sbjct: 1114 GLHAPRLS--LEGAARGAAEAKHKAP 1137 Score = 52.4 bits (124), Expect = 2e-06 Identities = 75/297 (25%), Positives = 103/297 (34%), Gaps = 53/297 (17%) Query: 699 PHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGL-VNGAASSAGIPEPPRLQGR 757 P +P PP PPP+ + PPP + PP +L+ L SS IP PP Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPP----- 212 Query: 758 GGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLP-PSWKYSPNIRAPPP------ 810 ++ P L P P P P P+ P P+ ++ R PP Sbjct: 213 -------------DFIPPAPPLAFLAP-PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258 Query: 811 ---IAYN---PLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCF 864 +A N + P + PK + GP P F P ++T+ Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR-SFKVPPPTPVRTSSIPV 317 Query: 865 DEVPPTPGPIASGSPKTARVQ-------EIRRFSTPAPQPTAEPLAPTVL------APRA 911 E P G+ K A + IR S P EP P L +PR Sbjct: 318 QEAQEAPRK-EEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376 Query: 912 ATTLDEPIWR--TELASAPVPSPA---PPPEAPRGLGASPSSCGFQVARPRFSATRT 963 + + R T + P+P PA PPP P A P C + A P T+T Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKT 433 Score = 43.1 bits (100), Expect = 0.001 Identities = 54/187 (28%), Positives = 68/187 (36%), Gaps = 28/187 (14%) Query: 96 PSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPR 155 P P P +S P G+P+P P P + PP S A P + Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSP--PSTAPPPPPLLLEPPPPPSMAPPPPPVLEAL 197 Query: 156 RPRR--RGPTRPTPPG----APPDEVYLSDSPAEPAPTIPGP--PSQGDSRVSSP----S 203 P P+ PTPP APP P PAP P P P +R+ P Sbjct: 198 SPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTK 257 Query: 204 WEDGAAL----------QPP--PAEALLLPHGPLRPGPHL-IPMVGPVPHPVAEDLTTTY 250 W+ AL PP PAE GP P PHL P VP P ++ Sbjct: 258 WKSDVALNGRQAEATRASPPRSPAEPKGSALGP-NPEPHLTFPRSFKVPPPTPVRTSSIP 316 Query: 251 TQKAKQA 257 Q+A++A Sbjct: 317 VQEAQEA 323 Score = 41.6 bits (96), Expect = 0.004 Identities = 128/548 (23%), Positives = 174/548 (31%), Gaps = 136/548 (24%) Query: 464 FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTS 523 FN + T L+ + + F PL + N L +P+ P + + T S + Sbjct: 58 FNTVSESGTATLKARPRVRPLLTFLPLNAQE-NHGLAVPTPSVPDDFADKEVTGTSSLVN 116 Query: 524 GVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIF 583 G + + S R P L IP P PG + PP + + S S Sbjct: 117 G---NLRLYSSVGDLR---PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS-- 168 Query: 584 LSAPLRPSARPEAPAPGPGAPEPPSAREQRI----------------------------- 614 +AP P E P P AP PP E Sbjct: 169 -TAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP 227 Query: 615 --SVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGP 672 VPA GTR +F PG S ++L E RA S Sbjct: 228 PPPVPAPAPPAPASPHTVGTR--LFPPGGVTKWKSD----VALNGRQAEATRASPPRSPA 281 Query: 673 EEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPP-PVAPKPPS 731 E +LG P+ P P + K PPP +T PV + Sbjct: 282 EPKGSALG------------------PNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323 Query: 732 RGLLDGLVNGAASSAGIPEPPRLQGR-GGELFAKRQSRAD---RYVVEGTPGPGLG---- 783 +G A S +P PP R +++ R D P LG Sbjct: 324 PRKEEGATKKAPSR--LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381 Query: 784 ---PRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQS-----QG 835 R +P P P LPP P PPP +P P AA LP AQ G Sbjct: 382 QADERAGTPPPAPPLPP-----PAPPLPPP-------APPLPPAAPPLPCAQKAAHPPAG 429 Query: 836 PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSP----KTARVQEIR--- 888 TPK AL + +P PP+P AS +P ++++++R Sbjct: 430 FTKTPKSSSPAL---KPKPN------------PPSPENTASSAPVDWRDPSQMEKLRNEL 474 Query: 889 -----------RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPE 937 RF + P PT +AP + L E + L S P PP Sbjct: 475 AAYLCGSRREDRFLSHRPGPT---VAPQSKEGKKGPRLPE---KETLLSLPA-KDTPPGV 527 Query: 938 APRGLGAS 945 + LG S Sbjct: 528 PEKSLGGS 535 Score = 36.2 bits (82), Expect = 0.15 Identities = 98/421 (23%), Positives = 136/421 (32%), Gaps = 77/421 (18%) Query: 28 RKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHASAMSLIDASGNQLVLTVQRL 87 R P Q+ K+R A G R D+ LSH TV Sbjct: 462 RDPSQMEKLRNELAAYLCGSRREDRF----------LSHRPGP------------TVAPQ 499 Query: 88 ADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADG 147 + EG P + +LS P PPG VP+ GS S ++EA T D Sbjct: 500 SKEGKKGPRLPEKETLLS--LPAKDTPPG--VPEKSLGGS--SLTETEAAPSLTLPSVDY 553 Query: 148 -PATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPG----PPSQGDSRVSSP 202 P P + R A E S P P + G D ++S P Sbjct: 554 IPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKP 613 Query: 203 SWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGP--VPHPVAEDLTTTYTQKAKQAKLQ 260 A PP LLP L+P L P + P P P T + +A L Sbjct: 614 -----VAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLG 668 Query: 261 RAESLQEKSIKEAKTKCRT---IASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAA 317 A L+ S K + IAS T P S+ LM Sbjct: 669 PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQ--LM-------------------- 706 Query: 318 GTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLG 377 AE++ G E +E + +++ S ++ L + AR+ S A + S G Sbjct: 707 ---AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARS-SAAFPPKTSPGG 762 Query: 378 GQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPP 437 G+ V + S ++E+A V P G P PP PP Sbjct: 763 GE--------VPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPP 814 Query: 438 S 438 + Sbjct: 815 A 815 >gi|118402590 myosin XV [Homo sapiens] Length = 3530 Score = 78.2 bits (191), Expect = 4e-14 Identities = 181/721 (25%), Positives = 232/721 (32%), Gaps = 158/721 (21%) Query: 298 FKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYL 357 F RQR + L +FGA G G E G P + A S AR L P Sbjct: 534 FLTPRQRNLQRALSAFGAHRGLGFGPEFGRP------VPRPATSLARFLKKTLSEKKPIA 587 Query: 358 DM---ELARAGSRASEGQ-----GSGLGGQLSEVSGRGVQLFEQQ---RQRADSSTQELA 406 + + ARAG A G L G E G + L Q R D+ Sbjct: 588 RLRGSQKARAGGPAVREAAYKRFGYKLAGMDPEKPGTPIVLRRAQPRARSSNDARRPPAP 647 Query: 407 RVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPL-PAPVASPRPFQPGGGAPTPAPSIFN 465 + P + + L SPP PP + P PL PA PRP P G Sbjct: 648 QPAPRTLSHWSALLSPP-VPPRPPSSGPPPAPPLSPALSGLPRPASPYG----------- 695 Query: 466 RSARPFTPGLQGQRPTTTSVIFRPLAPKR---ANDSLGGLSPAPPPFLSSQGPTPLPSFT 522 L+ P + P AP+ A +SP PP L + P P PSF Sbjct: 696 --------SLRRHPPPWAAPAHVPPAPQASWWAFVEPPAVSPEVPPDLLA-FPGPRPSFR 746 Query: 523 SGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPG-GAPEPPAPPSAAAMTSTAS 581 A ++PR+S A S L P PS +PG G P APPS T Sbjct: 747 GSRRRGAAFGFPGASPRASRR-RAWSPLASPQPSLRSSPGLGYCSPLAPPSPQLSLRTGP 805 Query: 582 I---FLSAPLRPSARPEAPAP--------GPGAPEPPSAREQRISVPAARTGILQEARRR 630 FL RP + E+PAP PG+P P S R P+ G+ RR Sbjct: 806 FQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRP-----PSPPLGLCHSPRRS 860 Query: 631 GTRKQMFRPGKEETKNSPNPELLSLVQNLD-EKPRAGGAESGPEEDALSLGAEACNFMQP 689 P + P + L +P GA P E S +P Sbjct: 861 SLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAWRAPLEHRESP-------REP 913 Query: 690 VGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIP 749 + TP T PP+AP M P PP +P P G G + +P Sbjct: 914 EDSE--------TPWTVPPLAPSWDVDMPPTQRPP-SPWPGGAGSR----RGFSRPPPVP 960 Query: 750 EPPRLQGRG---GELFAKRQSRADRYVV----EGTPGPG-----LGPRPRSPS------- 790 E P LQ G AD V PGPG GP P P Sbjct: 961 ENPFLQLLGPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKSAGPTPEKPEEEATLGD 1020 Query: 791 ---------PTPS-----LPPSWKYSPNIRAPPPIAYNPLLSPFFPQAA----------- 825 PTP+ PP P P P LS +P AA Sbjct: 1021 PQLPAETKPPTPAPPKDVTPPKDITPPKDVLPEQKTLRPSLS--YPLAACDQTRATWPPW 1078 Query: 826 ---RTLPKAQS-----QGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASG 877 TLP+A + + P PK G + PG A Sbjct: 1079 HRWGTLPQAAAPLAPIRAPEPLPKGG---------------------ERRQAAPGRFAVV 1117 Query: 878 SPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPE 937 P+ ++ +R +P +P+ PRA + +W A P P P+ Sbjct: 1118 MPRVQKLSSFQRVGPATLKPQVQPIQDP--KPRACSLRWSCLWLRADAYGPWPRVHTHPQ 1175 Query: 938 A 938 + Sbjct: 1176 S 1176 Score = 60.5 bits (145), Expect = 8e-09 Identities = 147/615 (23%), Positives = 203/615 (33%), Gaps = 158/615 (25%) Query: 450 FQPGGGAPTPAPSI----FNRSA----RPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG 501 F P G P P P+ F + +P Q+ R A KR L G Sbjct: 557 FGPEFGRPVPRPATSLARFLKKTLSEKKPIARLRGSQKARAGGPAVREAAYKRFGYKLAG 616 Query: 502 LSPAPP--PFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPV 559 + P P P + + P S + P + P+ PR+ +A S P P RP Sbjct: 617 MDPEKPGTPIVLRRAQ---PRARSSNDARRPPAPQPA-PRTLSHWSALLSP--PVPPRPP 670 Query: 560 TPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAP--------EPPSARE 611 + G P PP P+ + + AS + S P APA P AP EPP+ Sbjct: 671 SSGPPPAPPLSPALSGLPRPASPYGSLRRHPPPW-AAPAHVPPAPQASWWAFVEPPAVSP 729 Query: 612 Q----RISVPAARTGILQEARR-----------RGTRKQMFRPGKEETKNSPNPELLSLV 656 + ++ P R RR R +R++ + P SP P L S Sbjct: 730 EVPPDLLAFPGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSP-----LASPQPSLRS-- 782 Query: 657 QNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGAR-SYKTLPHVTPKTPPPMAPK--- 712 S G C+ + P + S +T P P PP P+ Sbjct: 783 ---------------------SPGLGYCSPLAPPSPQLSLRTGPFQPPFLPPARRPRSLQ 821 Query: 713 -TPPPM-------TPKTPPPVAPKPPSRGLLDGLVNG-AASSAGIP-----------EPP 752 +P P P +P P +P+PPS L GL + SS +P EPP Sbjct: 822 ESPAPRRAAGRLGPPGSPLPGSPRPPSPPL--GLCHSPRRSSLNLPSRLPHTWRRLSEPP 879 Query: 753 ------------RLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPS------PTPS 794 R G A + R E + P P P +PS PT Sbjct: 880 TRAVKPQVRLPFHRPPRAGAWRAPLEHRESPREPEDSETPWTVP-PLAPSWDVDMPPTQR 938 Query: 795 LPPSWKYSPNIR----APPPIAYNPLLSPFFPQAARTLPKAQSQGPRAT----------- 839 P W R PPP+ NP L P + TL Q + P A Sbjct: 939 PPSPWPGGAGSRRGFSRPPPVPENPFLQLLGPVPSPTL---QPEDPAADMTRVFLGRHHE 995 Query: 840 --PKQGIKALDFMRHQPYQ---LKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPA 894 P Q K+ +P + L + PPTP P +P + TP Sbjct: 996 PGPGQLTKSAGPTPEKPEEEATLGDPQLPAETKPPTPAPPKDVTPP--------KDITPP 1047 Query: 895 PQ--PTAEPLAPTVLAPRAATTLDEPIW----------RTELASAPVPSPAPPPEAPRGL 942 P + L P++ P AA W + AP+ +P P P+ Sbjct: 1048 KDVLPEQKTLRPSLSYPLAACDQTRATWPPWHRWGTLPQAAAPLAPIRAPEPLPKGGERR 1107 Query: 943 GASPSSCGFQVARPR 957 A+P F V PR Sbjct: 1108 QAAPGR--FAVVMPR 1120 Score = 33.9 bits (76), Expect = 0.76 Identities = 37/135 (27%), Positives = 48/135 (35%), Gaps = 32/135 (23%) Query: 110 LSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPG 169 LS P A PQ P PP + A+ + +E PR P PP Sbjct: 875 LSEPPTRAVKPQVRLP--FHRPPRAGAWRAPLEH-------RESPREPEDSETPWTVPPL 925 Query: 170 APPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGP 229 AP +V D P P P P G R S +PPP +P P Sbjct: 926 APSWDV---DMPPTQRPPSPWPGGAGSRRGFS---------RPPP-----VPENP----- 963 Query: 230 HLIPMVGPVPHPVAE 244 + ++GPVP P + Sbjct: 964 -FLQLLGPVPSPTLQ 977 Score = 32.7 bits (73), Expect = 1.7 Identities = 56/212 (26%), Positives = 71/212 (33%), Gaps = 19/212 (8%) Query: 92 PVQSPSPHELQVLSPL--SPLSPEPP--GAPVPQPLQPGSLRSPPDSEAYYGETDSDADG 147 P P+P L S L P+ P PP G P PL P P + Y Sbjct: 645 PAPQPAPRTLSHWSALLSPPVPPRPPSSGPPPAPPLSPALSGLPRPASPYGSLRRHPPPW 704 Query: 148 PATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDG 207 A P P+ PP P+ D A P P P +G R + G Sbjct: 705 AAPAHVPPAPQASWWAFVEPPAVSPE--VPPDLLAFPGPR---PSFRGSRRRGAAFGFPG 759 Query: 208 AALQPPPAEA---LLLPHGPLRPGPHL---IPMVGPVPHPVAEDLTTTYTQKAKQAKLQR 261 A+ + A L P LR P L P+ P P L T Q +R Sbjct: 760 ASPRASRRRAWSPLASPQPSLRSSPGLGYCSPLAPPSPQ---LSLRTGPFQPPFLPPARR 816 Query: 262 AESLQEK-SIKEAKTKCRTIASLLTAAPNPHS 292 SLQE + + A + S L +P P S Sbjct: 817 PRSLQESPAPRRAAGRLGPPGSPLPGSPRPPS 848 Score = 32.3 bits (72), Expect = 2.2 Identities = 42/183 (22%), Positives = 62/183 (33%), Gaps = 30/183 (16%) Query: 564 APEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGI 623 A +PPAP + T LR + +P APAP AP P P A + Sbjct: 2490 AEKPPAPEAQPTSVGTGPPAKPVLLRATPKPLAPAPLAKAPRLPIK-------PVAAPVL 2542 Query: 624 LQEARRRGTRKQMFRPGKEETKNS-----PNPELLSLVQNLDEKPRAGGAES-------- 670 Q+ T + T NS P ++ ++V+ + R G E+ Sbjct: 2543 AQDQASPETTSPSPELVRYSTLNSEHFPQPTQQIKNIVRQYQQPFRGGRPEALRKDGGKV 2602 Query: 671 -----GPEEDALSLGAEACNFM-----QPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPK 720 P E+AL + + V + + VT P MAP + P Sbjct: 2603 FMKRPDPHEEALMILKGQMTHLAAAPGTQVSREAVALVKPVTSAPRPSMAPTSALPSRSL 2662 Query: 721 TPP 723 PP Sbjct: 2663 EPP 2665 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 78.2 bits (191), Expect = 4e-14 Identities = 138/585 (23%), Positives = 196/585 (33%), Gaps = 157/585 (26%) Query: 378 GQLSEVSGRGVQLFEQQRQRADSSTQEL---ARVEPAAMLNGEGLQSPPRAQSAPPEAAV 434 G+ S VS Q R R SS+ + ++ + +G L S ++ P E++ Sbjct: 394 GRFSSVSS------PQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQP-ESST 446 Query: 435 LPPSPLPAPVASPRPFQPGGGAPTPAPSIFN-RSARPFTPGLQGQRPTTTSVIFRPLAPK 493 S +P P P GG+ A + RS+ G R + + RP P Sbjct: 447 ASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSS-----GQLSGRSVSLRKLKRPPPPP 501 Query: 494 RANDSL---------GGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPV 544 R SL G L P P Q P P T G A + P P +S Sbjct: 502 RRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEG-AGAAPCPPNPANS--- 557 Query: 545 TATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTA-SIFLSAPLRPSARPEAPAPGPGA 603 ++P ++PGG+ PP P S+ S P P P PG Sbjct: 558 ------WVPG----LSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGK 607 Query: 604 PEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNL--DE 661 +PP +P + + SP + S + +L Sbjct: 608 AQPP------------------------------KPERVTSLRSPGASVSSSLTSLCSSS 637 Query: 662 KPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKT 721 A SGP+ + P+G R + PH PK P AP +PPP P++ Sbjct: 638 SDPAPSDRSGPQ------------ILTPLGDR-FVIPPH--PKVP---APFSPPPSKPRS 679 Query: 722 PPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPG 781 P P AP + ++ G V + + A PP TP Sbjct: 680 PNPAAPALAAPAVVPGPV--STTDASPQSPP------------------------TPQTT 713 Query: 782 LGPRPRSP------SPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQG 835 L P SP SP PS PPS Y P PPP P + P A+ T + Q Sbjct: 714 LTPLQESPVISKDQSPPPSPPPS--YHP----PPPPTKKPEVVVEAPSASET-AEEPLQD 766 Query: 836 PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASG-SPKTARVQEIRRFSTPA 894 P P PP P P S E FS + Sbjct: 767 PNWPP---------------------------PPPPAPEEQDLSMADFPPPEEAFFSVAS 799 Query: 895 PQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAP 939 P+P +P +++ AA++ + + +P P PAPP AP Sbjct: 800 PEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844 Score = 72.4 bits (176), Expect = 2e-12 Identities = 104/440 (23%), Positives = 148/440 (33%), Gaps = 55/440 (12%) Query: 429 PPEAAVLPP-SPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIF 487 PP V P SP P+ SP P P AP P + T Q P T Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVS------TTDASPQSPPTPQTTL 714 Query: 488 RPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGS--------PSTPR 539 PL P+PPP S P P P+ V AP + P+ P Sbjct: 715 TPLQESPVISKDQSPPPSPPP---SYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPP 771 Query: 540 SSGPVTATSSLYI---PAPSR---------PVTPGGAPEPPAPPSAAAMTSTASIFLSAP 587 P L + P P P P G+PE + P+A++ ++TA Sbjct: 772 PPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATA-----LQ 826 Query: 588 LRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNS 647 ++P P+ P P P AP P S+ ++ L + G K P ++ Sbjct: 827 IQPPGSPDPP-PAPPAPAPASSAPGHVAK-------LPQKEPVGCSKGGGPPREDVGAPL 878 Query: 648 PNPELLSLVQNLDEKPRAGGAES---GPEEDALSLGAEACNFMQPVGARSYKTLPHVTPK 704 P LL +V+ L GGA + GP L PV A S V K Sbjct: 879 VTPSLLQMVR-LRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLK 937 Query: 705 TPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAK 764 A + P PP P+PP + +S + R + + Sbjct: 938 ACSLAASEGLSSAQPNGPPEAEPRPPQSP-------ASTASFIFSKGSRKLQLERPVSPE 990 Query: 765 RQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYN-PLLSPFFPQ 823 Q+ R +V P++P +P PP P++ PPP + + P P Sbjct: 991 TQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAP 1050 Query: 824 AARTLPKAQSQGPRATPKQG 843 LP Q + R + G Sbjct: 1051 PTNGLPHTQDRTKRELAENG 1070 Score = 62.4 bits (150), Expect = 2e-09 Identities = 129/546 (23%), Positives = 183/546 (33%), Gaps = 95/546 (17%) Query: 108 SPLSPEPPGAPVPQPLQPGSLRSP-------PDSEAYYGETDSD-------ADGPATQEK 153 +P P P + VP GS R P S Y ++ + A PA+ K Sbjct: 548 APCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGK 607 Query: 154 PRRPRRRGPTRPTPPGAPPDE--VYLSDSPAEPAPTIPGPPS----QGDSRVSSPSWEDG 207 + P+ T PGA L S ++PAP+ P GD V P + Sbjct: 608 AQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVP 667 Query: 208 AALQPPPAEALLLPHGPLRPGPHLIPMVGP--VPHPVAEDLTTTYTQKAKQAKLQRAESL 265 A PPP++ P P P + P VP PV+ TT + ++ L Sbjct: 668 APFSPPPSK-------PRSPNPAAPALAAPAVVPGPVS---TTDASPQSPPTPQTTLTPL 717 Query: 266 QEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEE-- 323 QE + I+ + P+P + KK +V +A AEE Sbjct: 718 QESPV---------ISKDQSPPPSPPPS----YHPPPPPTKKPEVVVEAPSASETAEEPL 764 Query: 324 -EDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSE 382 + PP +E+ S +D+ P A + + +G G Sbjct: 765 QDPNWPPPPPPAPEEQDLS-------MADFPPP------EEAFFSVASPEPAGPSGSPEL 811 Query: 383 VSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPA 442 VS A SS+ +++P G PP A AP A+ P Sbjct: 812 VSS----------PAASSSSATALQIQP------PGSPDPPPAPPAPAPASSAPGHVAKL 855 Query: 443 PVASPRPFQPGG-------GAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRA 495 P P GG GAP PS+ + R + G G PT P P R Sbjct: 856 PQKEPVGCSKGGGPPREDVGAPLVTPSLL-QMVRLRSVGAPGGAPTPALGPSAPQKPLRR 914 Query: 496 NDSLGGLSPAPPPFLSSQGPTPLP----SFTSGVPSHAPVSGSPSTPRSSGPVTATSSLY 551 S G SP P P L + + G+ S P + PR +T+S Sbjct: 915 ALS-GRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFI 973 Query: 552 IPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSARE 611 SR + E P P A + + P+AP P AP PP AR+ Sbjct: 974 FSKGSRKL----QLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAP-PPVARK 1028 Query: 612 QRISVP 617 + VP Sbjct: 1029 PSVGVP 1034 Score = 60.5 bits (145), Expect = 8e-09 Identities = 92/364 (25%), Positives = 124/364 (34%), Gaps = 93/364 (25%) Query: 420 QSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQR 479 QSPP Q+ L SP+ + SP P P P P P+ ++ Sbjct: 705 QSPPTPQTT---LTPLQESPVISKDQSPPPSPPPSYHPPPPPT---------------KK 746 Query: 480 PTTTSVIFRPLAPKRANDSLGGLS--PAPPPFLSSQG------PTPLPSFTSGVPSHAPV 531 P V+ P A + A + L + P PPP Q P P +F S V S P Sbjct: 747 PEV--VVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFS-VASPEPA 803 Query: 532 SGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTA----------- 580 S S S P ++SS A + + P G+P+PP P A A S+A Sbjct: 804 GPSGSPELVSSPAASSSS----ATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKE 859 Query: 581 ----------------------SIFLSAPLRPSARP---EAPAPGPGAPEPPSARE---Q 612 S+ LR P PA GP AP+ P R + Sbjct: 860 PVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGR 919 Query: 613 RISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGP 672 VPA +G+ R + N P PE +PR + + Sbjct: 920 ASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGP-PEA---------EPRPPQSPAST 969 Query: 673 EEDALSLGAEACNFMQPVGARSYKTLPH-------VTPKTPPPMAPKTPPPMTPKTPPPV 725 S G+ +PV + L + PP APK +PK PPPV Sbjct: 970 ASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKK----SPKAPPPV 1025 Query: 726 APKP 729 A KP Sbjct: 1026 ARKP 1029 Score = 52.8 bits (125), Expect = 2e-06 Identities = 140/562 (24%), Positives = 187/562 (33%), Gaps = 100/562 (17%) Query: 112 PEPPG-APVPQPLQPGSLRSPPDS-EAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPG 169 P PG A P+P + SLRSP S + S + PA + R GP TP G Sbjct: 602 PASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSD------RSGPQILTPLG 655 Query: 170 APPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRPGP 229 D + P PAP P P S+ SP+ P A AL P + PGP Sbjct: 656 ---DRFVIPPHPKVPAPFSPPP-----SKPRSPN---------PAAPALAAP--AVVPGP 696 Query: 230 HLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPN 289 P P + TT T LQE + I+ + P+ Sbjct: 697 VSTTDASPQSPPTPQ---TTLT------------PLQESPV---------ISKDQSPPPS 732 Query: 290 PHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEE------DGVPPTSESELD------- 336 P + KK +V +A AEE PP + E D Sbjct: 733 PPPS----YHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP 788 Query: 337 --EEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQ 394 EEAF S SP L A + S A+ Q G + Sbjct: 789 PPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPA----PAP 844 Query: 395 RQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGG 454 A +L + EP G G PPR P ++ PS L + R G Sbjct: 845 ASSAPGHVAKLPQKEPVGCSKGGG---PPREDVGAP---LVTPSLL--QMVRLRSVGAPG 896 Query: 455 GAPTPA--PSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPK----RANDSLGGLSPAPPP 508 GAPTPA PS + R G P +S + + K A++ L P PP Sbjct: 897 GAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPP 956 Query: 509 FLS---SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 565 Q P SF S P +P + + + + S P AP Sbjct: 957 EAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQ-RPPQAP 1015 Query: 566 E--PPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGI 623 + P APP A S ++P P A P P G P ++ + A G+ Sbjct: 1016 KKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKREL---AENGGV 1072 Query: 624 LQEARRRGTRKQMFRPGKEETK 645 LQ G ++M PG + K Sbjct: 1073 LQLV---GPEEKMGLPGSDSQK 1091 Score = 46.2 bits (108), Expect = 1e-04 Identities = 66/286 (23%), Positives = 101/286 (35%), Gaps = 44/286 (15%) Query: 93 VQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGP---- 148 V++PS E PL + PP P P+ PP EA++ + GP Sbjct: 751 VEAPSASETAE-EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSP 809 Query: 149 -------ATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSS 201 A+ + + P P PP APP S +P A +P G S+ Sbjct: 810 ELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVA-KLPQKEPVGCSKGGG 868 Query: 202 PSWED-GAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQ 260 P ED GA L P ++ PG P +GP A Q L+ Sbjct: 869 PPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGP---------------SAPQKPLR 913 Query: 261 RAESLQEKSIKEAKT---------KCRTIAS--LLTAAPNPHSKGVLMFKKRRQRAKKYT 309 RA S + + + C AS L +A PN G + R ++ T Sbjct: 914 RALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPN----GPPEAEPRPPQSPAST 969 Query: 310 LVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSP 355 + + E V P ++++L ++ RS++ Q +P Sbjct: 970 ASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAP 1015 Score = 45.4 bits (106), Expect = 3e-04 Identities = 112/499 (22%), Positives = 160/499 (32%), Gaps = 113/499 (22%) Query: 88 ADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQP------------GSLRSPPDSE 135 +D P P Q+L+PL PP VP P P +L +P Sbjct: 638 SDPAPSDRSGP---QILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVP 694 Query: 136 AYYGETDSDADGPATQEKPRRPRRRGPT---RPTPPGAPPDEVYLSDSPAEPAPTIPGPP 192 TD+ P T + P + P +PP +PP + P + + P Sbjct: 695 GPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAP 754 Query: 193 SQGDSR---VSSPSW-----------EDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPV 238 S ++ + P+W + A PPP EA P GP P + V Sbjct: 755 SASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPEL--V 812 Query: 239 PHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMF 298 P A + T Q +Q + AP P S Sbjct: 813 SSPAASSSSATALQ------------IQPPGSPDPPP--------APPAPAPASSAPGHV 852 Query: 299 KKRRQRAKKYTLVSFGAAAGTGAEEED-GVPPTSESELDEEAFSDARSLTNQSDWDSPYL 357 K Q+ G + G G ED G P + S L RS+ +P L Sbjct: 853 AKLPQKE------PVGCSKGGGPPREDVGAPLVTPSLLQ---MVRLRSVGAPGGAPTPAL 903 Query: 358 DMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGE 417 + R + L G+ S V S R++ ++ E Sbjct: 904 GPSAPQKPLRRA------LSGRASPVPA------------PSSGLHAAVRLKACSLAASE 945 Query: 418 GLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG 477 GL S + PPEA PP PA AS IF++ +R LQ Sbjct: 946 GLSS--AQPNGPPEAEPRPPQS-PASTAS---------------FIFSKGSRK----LQL 983 Query: 478 QRPT---TTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGS 534 +RP T + + R L + L +S PP + P P P S Sbjct: 984 ERPVSPETQADLQRNLVAE-----LRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPAS 1038 Query: 535 PSTPRSSGPVTATSSLYIP 553 PS PR+ P+TA + +P Sbjct: 1039 PSYPRAE-PLTAPPTNGLP 1056 Score = 33.5 bits (75), Expect = 1.00 Identities = 70/299 (23%), Positives = 91/299 (30%), Gaps = 66/299 (22%) Query: 87 LADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAY-----YGET 141 L S S LQ+ P SP P P AP P PG + P E G Sbjct: 811 LVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPP 870 Query: 142 DSDADGP-ATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEP--------APTIPGPP 192 D P T + R R PG P +P +P A +P P Sbjct: 871 REDVGAPLVTPSLLQMVRLRS---VGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPS 927 Query: 193 S--------QGDSRVSSPSWEDGAALQPPPAEALLLPHGPLRP----------GPHLIPM 234 S + S +S PP AE P P P G + + Sbjct: 928 SGLHAAVRLKACSLAASEGLSSAQPNGPPEAE----PRPPQSPASTASFIFSKGSRKLQL 983 Query: 235 VGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCR--------------TI 280 PV DL + + QR +KS K R Sbjct: 984 ERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPR 1043 Query: 281 ASLLTAAPN---PHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPT-SESEL 335 A LTA P PH+ + R K+ + G G EE+ G+P + S+ EL Sbjct: 1044 AEPLTAPPTNGLPHT---------QDRTKRELAENGGVLQLVGPEEKMGLPGSDSQKEL 1093 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 77.4 bits (189), Expect = 6e-14 Identities = 193/950 (20%), Positives = 283/950 (29%), Gaps = 124/950 (13%) Query: 92 PVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQ 151 P +PSP +P +P PP P P + PP + T + P T Sbjct: 1558 PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTT 1617 Query: 152 EKPRRPRRRGPTRPTPPGAPPDEVYLSDSP----AEPAPTIPGPPSQGDSRVSSPSWEDG 207 P P T PT P S P P T P PP+ ++PS Sbjct: 1618 PSP--PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT-----TTTPSPPIT 1670 Query: 208 AALQPPPAEALLLPHGPL--RPGPHLIPMVGPVPHPV-AEDLTTTYTQKAKQAKLQRAES 264 PPP P P+ P P M P P + +TTT T + + Sbjct: 1671 TTTTPPPTTT---PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTT 1727 Query: 265 LQEKSIKEAKT---------KCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGA 315 + S + T +S LT P P S F V Sbjct: 1728 MTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCN 1787 Query: 316 AAGTGAEEEDGVPPTSESELDEEAFSDARS---LTNQSDWDSPYLDMELARAGSRASEGQ 372 G + G P + D E D N S + Y D+ + + G Sbjct: 1788 WTGW---LDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDV 1844 Query: 373 GSGLGGQLSEVSGRGV------QLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQ 426 GL + + GV +E Q + TQ P M P Sbjct: 1845 SVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQ------PTTMTTTTTENPTPPTT 1898 Query: 427 SAPPEAAVLPPSPLP-------------APVASPRPFQPGGGAPTPAPSIFNRSARPFTP 473 + + P+P P +P P G PT P + P Sbjct: 1899 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1958 Query: 474 GLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSG 533 Q PTTT + + ++P P P +Q PT P T+ + P Sbjct: 1959 PTGTQTPTTTPI-----------TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPT 2006 Query: 534 SPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSAR 593 TP ++ P+T T+++ P P TP G P P T T + + P+ Sbjct: 2007 GTQTPTTT-PITTTTTV-TPTP----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2060 Query: 594 P------EAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNS 647 P P P P + P+ + T + GT+ P T + Sbjct: 2061 PITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2115 Query: 648 PNP----------ELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKT 697 P P ++ + P G ++ P ++ P G ++ T Sbjct: 2116 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTT 2174 Query: 698 LP-----HVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGI---P 749 P VTP TP P +TP T V P P G ++ + P Sbjct: 2175 TPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2233 Query: 750 EPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIR-AP 808 P Q + GT P P + + TP+ P+ +P Sbjct: 2234 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293 Query: 809 PPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVP 868 P +P Q T P + TP T + V Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVT 2345 Query: 869 PTPGPIASGSPKTARVQEIRRFS-TPAP----QPTAEPL-APTVLAPRAATTLDEPIWRT 922 PTP P + +P T + + TP P PT P+ T + P T + T Sbjct: 2346 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2405 Query: 923 ELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRFSATRTGLQAHVWRP 972 + + +P P P + +P + V + T TG Q P Sbjct: 2406 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTP 2452 Score = 76.6 bits (187), Expect = 1e-13 Identities = 99/444 (22%), Positives = 136/444 (30%), Gaps = 81/444 (18%) Query: 503 SPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPG 562 +P+PP + P+P P+ T+ +P S P+T ++ P T T PS P+T Sbjct: 1398 TPSPP----TTTPSPPPTSTTTLPPTTTPS-PPTTTTTTPPPTTT-------PSPPITTT 1445 Query: 563 GAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTG 622 P P PS T+T + P P+ P P P P + + P+ T Sbjct: 1446 TTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPT- 1504 Query: 623 ILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAE 682 T +P +L P + P S Sbjct: 1505 --------------------TTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTT 1544 Query: 683 ACNFMQPVGA-RSYKTLPHVTPKTPPPMAPKTPPPMTPKTPP-PVAPKPPSRGLLDGLVN 740 P+ S TLP T +PPP TPPP T +PP P PP+ + Sbjct: 1545 T-----PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPT------ITT 1593 Query: 741 GAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWK 800 P PP TP P P P P+ TP PP Sbjct: 1594 TTPPPTTTPSPPT-------------------TTTTTPPPTTTPSP--PTTTPITPP--- 1629 Query: 801 YSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTA 860 + PP +P P T P + P T P ++ Sbjct: 1630 -TSTTTLPPTTTPSPP-----PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSS 1683 Query: 861 MFCFDEVPP-----TPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTL 915 PP TP P + S +TP+P PT P TT Sbjct: 1684 PITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT 1743 Query: 916 DEPIWRTELASAPVPSPAPPPEAP 939 + T +S +P PP P Sbjct: 1744 MTTLPPTTTSSPLTTTPLPPSITP 1767 Score = 72.4 bits (176), Expect = 2e-12 Identities = 80/315 (25%), Positives = 108/315 (34%), Gaps = 27/315 (8%) Query: 422 PPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPT 481 PP +PP + P P P SP P TP+P + P P PT Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTP--SPPTTTPSPPTTTPSPPTTTTTTPP--PTTTPSPPT 1504 Query: 482 TTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSS 541 TT P+ P + +L + PP ++ TP P+ T P+ P+ +P T ++ Sbjct: 1505 TT-----PITPPASTTTLPPTTTPSPPTTTT--TTPPPTTTPSPPTTTPI--TPPTSTTT 1555 Query: 542 GPVTATSSLYIPAPSRPVTPGGAPEPPAP----PSAAAMTSTASIFLSAPLRPSARPEAP 597 P T T S P P+ TP P P PS +T+T + P P+ P Sbjct: 1556 LPPTTTPS---PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP 1612 Query: 598 APGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQ 657 P P PP+ I+ P + T + P T + P S Sbjct: 1613 PP-TTTPSPPTTTP--ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPI 1669 Query: 658 NLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPM 717 P S P S P S P T TP +PPP Sbjct: 1670 TTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS---SPITTTTTPSSTTTPSPPPT 1726 Query: 718 TPKTP-PPVAPKPPS 731 T TP P P PP+ Sbjct: 1727 TMTTPSPTTTPSPPT 1741 Score = 70.9 bits (172), Expect = 6e-12 Identities = 115/501 (22%), Positives = 146/501 (29%), Gaps = 116/501 (23%) Query: 439 PLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDS 498 P+ + +P P PT PS S P PTTT+ P Sbjct: 1391 PMDKCITTPSP-------PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTT------- 1436 Query: 499 LGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRP 558 +P+PP ++ TP P+ T P + P+T S P T T S PS P Sbjct: 1437 ----TPSPPITTTT---TPPPTTTPSPPISTTTTPPPTTTPS--PPTTTPSPPTTTPSPP 1487 Query: 559 VTPGGAPEP---PAPPSAAAMTSTASIFLSAPLRPSARPEAPA------PGPGAPEPPSA 609 T P P P+PP+ +T AS + L P+ P P P P PP+ Sbjct: 1488 TTTTTTPPPTTTPSPPTTTPITPPAS---TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTT 1544 Query: 610 REQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAE 669 I+ P + T + P T + P S P Sbjct: 1545 TP--ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602 Query: 670 SGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKP 729 S P + T P T +PP P TPP T PP P P Sbjct: 1603 SPP-------------------TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1643 Query: 730 PSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSP 789 P ++ P P TP P P P Sbjct: 1644 P------------PTTTTTPPPTT-----------------------TPSPPTTTTPSPP 1668 Query: 790 SPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDF 849 T + PP P PI P SP P T P P TP Sbjct: 1669 ITTTTTPP-----PTTTPSSPITTTP--SP--PTTTMTTP-----SPTTTPS-------- 1706 Query: 850 MRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAP 909 P T P P + + SP T +T P T+ PL T L P Sbjct: 1707 ---SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPP 1763 Query: 910 RAATTLDEPIWRTELASAPVP 930 P T + VP Sbjct: 1764 SITPPTFSPFSTTTPTTPCVP 1784 Score = 66.6 bits (161), Expect = 1e-10 Identities = 96/410 (23%), Positives = 127/410 (30%), Gaps = 62/410 (15%) Query: 436 PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRA 495 PP+ P+P + P P+P + TP TT P P Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIST 1460 Query: 496 NDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIP-- 553 + + PP + PT PS + + P + +PS P ++ S+ +P Sbjct: 1461 TTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPT 1520 Query: 554 -APSRPVTPGGAPEP---PAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSA 609 PS P T P P P+PP+ +T S + L P+ P P P P + Sbjct: 1521 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS---TTTLPPTTTPSPPPTTTTTPPPTTT 1577 Query: 610 REQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAE 669 S P T P T P S P Sbjct: 1578 P----SPPTTTTP---------------SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTP 1618 Query: 670 SGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPP-PVAPK 728 S P ++ S TLP T +PPP TPPP T +PP P Sbjct: 1619 SPPTTTPIT------------PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666 Query: 729 PPSRGLLDGLVNGAASS--AGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRP 786 PP SS P PP + + + TP P P Sbjct: 1667 PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTP---SPTTTPSSPITTTTTPSSTTTPSP 1723 Query: 787 -------RSPSPTPS--------LPPSWKYSPNIRAP-PPIAYNPLLSPF 820 SP+ TPS LPP+ SP P PP P SPF Sbjct: 1724 PPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPF 1773 Score = 63.5 bits (153), Expect = 9e-10 Identities = 78/321 (24%), Positives = 107/321 (33%), Gaps = 51/321 (15%) Query: 421 SPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP 480 SPP + P P P P+ P TP+P + P P P Sbjct: 1485 SPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPP--PTTTPSPP 1542 Query: 481 TTTSVIFRPLAPKRANDSL-GGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPR 539 TTT P+ P + +L +P+PPP ++ TP P+ T PS P + +PS P Sbjct: 1543 TTT-----PITPPTSTTTLPPTTTPSPPPTTTT---TPPPTTT---PS-PPTTTTPSPP- 1589 Query: 540 SSGPVTATSSLYIPAPSRPVTPGGAPEP---PAPPSAAAMTSTASIFLSAPLRPSARPEA 596 +T T+ PS P T P P P+PP+ +T S + L P+ P Sbjct: 1590 ---TITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS---TTTLPPTTTPSP 1643 Query: 597 P------APGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNP 650 P P P PP+ + T P T +SP Sbjct: 1644 PPTTTTTPPPTTTPSPPTTTTPSPPITTTTT-----------------PPPTTTPSSPIT 1686 Query: 651 ELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMA 710 S P S P + + P + T T +PP Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPT---TMTTPSPTTTPSPPTTT 1743 Query: 711 PKTPPPMTPKTPPPVAPKPPS 731 T PP T +P P PPS Sbjct: 1744 MTTLPPTTTSSPLTTTPLPPS 1764 Score = 62.0 bits (149), Expect = 3e-09 Identities = 114/558 (20%), Positives = 174/558 (31%), Gaps = 67/558 (12%) Query: 446 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 505 +P P G PT P + P Q PTTT + + ++P Sbjct: 2299 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----------TTTTVTPT 2347 Query: 506 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 565 P P +Q PT P T+ + P TP ++ P+T T+++ P P TP G Sbjct: 2348 PTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTV-TPTP----TPTGTQ 2400 Query: 566 EPPAPPSAAAMTSTASIFLSAPLRPSARP------EAPAPGPGAPEPPSAREQRISVPAA 619 P P T T + + P+ P P P P + P+ + Sbjct: 2401 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITT 2455 Query: 620 RTGILQEARRRGTRKQMFRPGKEETKNSPNP----------ELLSLVQNLDEKPRAGGAE 669 T + GT+ P T +P P ++ + P G + Sbjct: 2456 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2515 Query: 670 SGPEEDALSLGAEACNFMQPVGARSYKTLP-----HVTPKTPPPMAPKTPPPMTPKTPPP 724 + P ++ P G ++ T P VTP TP P +TP T Sbjct: 2516 T-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTT 2573 Query: 725 VAPKPPSRGLLDGLVNGAASSAGI---PEPPRLQGRGGELFAKRQSRADRYVVEGTPGPG 781 V P P G ++ + P P Q + GT P Sbjct: 2574 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2633 Query: 782 LGPRPRSPSPTPSLPPSWKYSPNIR-APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP 840 P + + TP+ P+ +P P +P Q T P + TP Sbjct: 2634 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2693 Query: 841 KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFS-TPAP---- 895 T + V PTP P + +P T + + TP P Sbjct: 2694 TP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2745 Query: 896 QPTAEPL-APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVA 954 PT P+ T + P T + T + + +P P P + +P + V Sbjct: 2746 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2805 Query: 955 RPRFSATRTGLQAHVWRP 972 + T TG Q P Sbjct: 2806 P---TPTPTGTQTPTTTP 2820 Score = 62.0 bits (149), Expect = 3e-09 Identities = 114/558 (20%), Positives = 174/558 (31%), Gaps = 67/558 (12%) Query: 446 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 505 +P P G PT P + P Q PTTT + + ++P Sbjct: 2736 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----------TTTTVTPT 2784 Query: 506 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 565 P P +Q PT P T+ + P TP ++ P+T T+++ P P TP G Sbjct: 2785 PTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTV-TPTP----TPTGTQ 2837 Query: 566 EPPAPPSAAAMTSTASIFLSAPLRPSARP------EAPAPGPGAPEPPSAREQRISVPAA 619 P P T T + + P+ P P P P + P+ + Sbjct: 2838 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITT 2892 Query: 620 RTGILQEARRRGTRKQMFRPGKEETKNSPNP----------ELLSLVQNLDEKPRAGGAE 669 T + GT+ P T +P P ++ + P G + Sbjct: 2893 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2952 Query: 670 SGPEEDALSLGAEACNFMQPVGARSYKTLP-----HVTPKTPPPMAPKTPPPMTPKTPPP 724 + P ++ P G ++ T P VTP TP P +TP T Sbjct: 2953 T-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTT 3010 Query: 725 VAPKPPSRGLLDGLVNGAASSAGI---PEPPRLQGRGGELFAKRQSRADRYVVEGTPGPG 781 V P P G ++ + P P Q + GT P Sbjct: 3011 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3070 Query: 782 LGPRPRSPSPTPSLPPSWKYSPNIR-APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP 840 P + + TP+ P+ +P P +P Q T P + TP Sbjct: 3071 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3130 Query: 841 KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFS-TPAP---- 895 T + V PTP P + +P T + + TP P Sbjct: 3131 TP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3182 Query: 896 QPTAEPL-APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVA 954 PT P+ T + P T + T + + +P P P + +P + V Sbjct: 3183 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3242 Query: 955 RPRFSATRTGLQAHVWRP 972 + T TG Q P Sbjct: 3243 P---TPTPTGTQTPTTTP 3257 Score = 62.0 bits (149), Expect = 3e-09 Identities = 114/558 (20%), Positives = 174/558 (31%), Gaps = 67/558 (12%) Query: 446 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 505 +P P G PT P + P Q PTTT + + ++P Sbjct: 3173 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----------TTTTVTPT 3221 Query: 506 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 565 P P +Q PT P T+ + P TP ++ P+T T+++ P P TP G Sbjct: 3222 PTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTV-TPTP----TPTGTQ 3274 Query: 566 EPPAPPSAAAMTSTASIFLSAPLRPSARP------EAPAPGPGAPEPPSAREQRISVPAA 619 P P T T + + P+ P P P P + P+ + Sbjct: 3275 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITT 3329 Query: 620 RTGILQEARRRGTRKQMFRPGKEETKNSPNP----------ELLSLVQNLDEKPRAGGAE 669 T + GT+ P T +P P ++ + P G + Sbjct: 3330 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3389 Query: 670 SGPEEDALSLGAEACNFMQPVGARSYKTLP-----HVTPKTPPPMAPKTPPPMTPKTPPP 724 + P ++ P G ++ T P VTP TP P +TP T Sbjct: 3390 T-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTT 3447 Query: 725 VAPKPPSRGLLDGLVNGAASSAGI---PEPPRLQGRGGELFAKRQSRADRYVVEGTPGPG 781 V P P G ++ + P P Q + GT P Sbjct: 3448 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3507 Query: 782 LGPRPRSPSPTPSLPPSWKYSPNIR-APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP 840 P + + TP+ P+ +P P +P Q T P + TP Sbjct: 3508 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3567 Query: 841 KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFS-TPAP---- 895 T + V PTP P + +P T + + TP P Sbjct: 3568 TP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3619 Query: 896 QPTAEPL-APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVA 954 PT P+ T + P T + T + + +P P P + +P + V Sbjct: 3620 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3679 Query: 955 RPRFSATRTGLQAHVWRP 972 + T TG Q P Sbjct: 3680 P---TPTPTGTQTPTTTP 3694 Score = 62.0 bits (149), Expect = 3e-09 Identities = 114/558 (20%), Positives = 174/558 (31%), Gaps = 67/558 (12%) Query: 446 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 505 +P P G PT P + P Q PTTT + + ++P Sbjct: 3610 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----------TTTTVTPT 3658 Query: 506 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 565 P P +Q PT P T+ + P TP ++ P+T T+++ P P TP G Sbjct: 3659 PTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTV-TPTP----TPTGTQ 3711 Query: 566 EPPAPPSAAAMTSTASIFLSAPLRPSARP------EAPAPGPGAPEPPSAREQRISVPAA 619 P P T T + + P+ P P P P + P+ + Sbjct: 3712 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITT 3766 Query: 620 RTGILQEARRRGTRKQMFRPGKEETKNSPNP----------ELLSLVQNLDEKPRAGGAE 669 T + GT+ P T +P P ++ + P G + Sbjct: 3767 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3826 Query: 670 SGPEEDALSLGAEACNFMQPVGARSYKTLP-----HVTPKTPPPMAPKTPPPMTPKTPPP 724 + P ++ P G ++ T P VTP TP P +TP T Sbjct: 3827 T-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTT 3884 Query: 725 VAPKPPSRGLLDGLVNGAASSAGI---PEPPRLQGRGGELFAKRQSRADRYVVEGTPGPG 781 V P P G ++ + P P Q + GT P Sbjct: 3885 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3944 Query: 782 LGPRPRSPSPTPSLPPSWKYSPNIR-APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP 840 P + + TP+ P+ +P P +P Q T P + TP Sbjct: 3945 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4004 Query: 841 KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFS-TPAP---- 895 T + V PTP P + +P T + + TP P Sbjct: 4005 TP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4056 Query: 896 QPTAEPL-APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVA 954 PT P+ T + P T + T + + +P P P + +P + V Sbjct: 4057 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4116 Query: 955 RPRFSATRTGLQAHVWRP 972 + T TG Q P Sbjct: 4117 P---TPTPTGTQTPTTTP 4131 Score = 59.3 bits (142), Expect = 2e-08 Identities = 70/289 (24%), Positives = 87/289 (30%), Gaps = 63/289 (21%) Query: 699 PHVTPKTPPPMAPKTPPPMTPKTPPPVA-PKPP-SRGLLDGLVNGAASSAGIPEPPRLQG 756 P T TPPP +PP T TPPP P PP S + P PP Sbjct: 1425 PTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTT-- 1482 Query: 757 RGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSP------TPSLPPSWKYSP---NIRA 807 + + TP P P P + +P T +LPP+ SP Sbjct: 1483 ----------TPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTT 1532 Query: 808 PPPIAYN--PLLSPFFPQAART-LPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCF 864 PPP P +P P + T LP + P T Sbjct: 1533 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT------------------------- 1567 Query: 865 DEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVL----------APRAATT 914 TP P + SP T +T P PT P PT +P T Sbjct: 1568 --TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1625 Query: 915 LDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRFSATRT 963 + P T L PSP P +PS P + T T Sbjct: 1626 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTT 1674 Score = 55.8 bits (133), Expect = 2e-07 Identities = 63/246 (25%), Positives = 79/246 (32%), Gaps = 23/246 (9%) Query: 701 VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGE 760 +T +PP P PP T PP P PP+ P PP Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPT------TTTTTPPPTTTPSPPITTTTTP- 1448 Query: 761 LFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSP---NIRAPPPIA--YNP 815 + + TP P P P P+ TPS PP+ SP PPP P Sbjct: 1449 --PPTTTPSPPISTTTTPPPTTTPSP--PTTTPS-PPTTTPSPPTTTTTTPPPTTTPSPP 1503 Query: 816 LLSPFFPQAA-RTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPI 874 +P P A+ TLP + P T T +PPT P Sbjct: 1504 TTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP- 1562 Query: 875 ASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPR-AATTLDEPIWRTELASAPVPSPA 933 SP +TP+P T P PT+ TT P T P +P+ Sbjct: 1563 ---SPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPS 1619 Query: 934 PPPEAP 939 PP P Sbjct: 1620 PPTTTP 1625 Score = 55.1 bits (131), Expect = 3e-07 Identities = 83/395 (21%), Positives = 128/395 (32%), Gaps = 42/395 (10%) Query: 446 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 505 +P P G PT P + P Q PTTT + + ++P Sbjct: 3909 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----------TTTTVTPT 3957 Query: 506 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 565 P P +Q PT P T+ + P TP ++ P+T T+++ P P TP G Sbjct: 3958 PTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTV-TPTP----TPTGTQ 4010 Query: 566 EPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVP-AARTGIL 624 P P T T + + P+ P P+ + + P T + Sbjct: 4011 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4070 Query: 625 QEARRRGTRKQMFRPGKEETKNSPNPEL----------LSLVQNLDEKPRAGGAESGPEE 674 GT+ P T +P P ++ + P G ++ P Sbjct: 4071 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTT 4129 Query: 675 DALSLGAEACNFMQPVGARSYKTLP-----HVTPKTPPPMAPKTPPPMTPKTPPPVAPKP 729 ++ P G ++ T P VTP TP P +TP T V P P Sbjct: 4130 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTP 4188 Query: 730 PSRGLLDGLVNGAASSAGIPE-----PPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGP 784 G G S+A I E PP + + + T P + Sbjct: 4189 TPTGTQTGPPT-HTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 4247 Query: 785 RPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSP 819 +P TP+ P + + PP +P +P Sbjct: 4248 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTP 4282 Score = 54.7 bits (130), Expect = 4e-07 Identities = 78/313 (24%), Positives = 113/313 (36%), Gaps = 46/313 (14%) Query: 446 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 505 +P P G PT P + P TP G + TT+ I G +P Sbjct: 4116 TPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4174 Query: 506 PPPFLSSQGPTPLPSFT---SGVPSHA--------------PVSGSPSTPRS-SGPVTAT 547 P ++ TP P+ T +G P+H P S +P T RS S P+T + Sbjct: 4175 TTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES 4234 Query: 548 SSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGP--GAPE 605 ++L P P + PP+ P+A TS P ++ P P G G+ Sbjct: 4235 TTLLSTLP--PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSS 4292 Query: 606 PPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKN-SPNPELLSLVQNLDEKPR 664 P+ + + +A T T + P T P P + + L++ Sbjct: 4293 APTPSTVQTTTTSAWTP---------TPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYY 4343 Query: 665 AGGAE--SGPEED-------ALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK-TP 714 A G E +G D +LS E N+ P + P + TP P P TP Sbjct: 4344 APGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCP---STPSPTPTPSKSTPTPSKPSSTP 4400 Query: 715 PPMTPKTPPPVAP 727 TP T PP P Sbjct: 4401 SKPTPGTKPPECP 4413 Score = 43.9 bits (102), Expect = 7e-04 Identities = 59/242 (24%), Positives = 79/242 (32%), Gaps = 72/242 (29%) Query: 421 SPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP 480 +P Q+ PP AP+A P + TP S S + L P Sbjct: 4189 TPTGTQTGPPTHTST------APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP 4242 Query: 481 -----TTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSP 535 T+T+ P AP + GG + +PPP ++ P G P+ +GS Sbjct: 4243 PAIEMTSTAPPSTPTAPTTTS---GGHTLSPPPSTTTSPP--------GTPTRGTTTGSS 4291 Query: 536 STPRSSGPVTATSSLYIPAPSRPVTP------GGAPEPP-------------AP------ 570 S P S T T+S + P P+ TP G P P AP Sbjct: 4292 SAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYN 4351 Query: 571 -------------------------PSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPE 605 PS + T T S P +PS+ P P PG PE Sbjct: 4352 GTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPE 4411 Query: 606 PP 607 P Sbjct: 4412 CP 4413 Score = 40.4 bits (93), Expect = 0.008 Identities = 39/163 (23%), Positives = 53/163 (32%), Gaps = 17/163 (10%) Query: 92 PVQSPSPHELQVLSPLSPLSPEPP------GAPVPQPLQPGSLRSPPDSEAYYGETDSDA 145 P +PSP +P +P PP P P P + SPP + T + Sbjct: 1434 PTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT 1493 Query: 146 DGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWE 205 P T P T P P A + + +P+ P T PP ++PS Sbjct: 1494 PPPTTTPSP------PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPP-----TTTPSPP 1542 Query: 206 DGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTT 248 + PP + L P P P P P TT Sbjct: 1543 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1585 Score = 38.5 bits (88), Expect = 0.031 Identities = 41/170 (24%), Positives = 56/170 (32%), Gaps = 14/170 (8%) Query: 92 PVQSPSPHELQVLSP------LSPLS-PEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSD 144 P +PSP ++P L P + P PP P P + SPP + T + Sbjct: 1496 PTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTP-PPTTTPSPPTTTPITPPTSTT 1554 Query: 145 ADGPATQEKPRRPRRRGP---TRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSR--- 198 P T P P T P+PP + P T P PP+ + Sbjct: 1555 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP 1614 Query: 199 VSSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTT 248 ++PS + PP + L P P P P P TT Sbjct: 1615 TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1664 Score = 35.8 bits (81), Expect = 0.20 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 3/81 (3%) Query: 869 PTPGPIASGS--PKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELAS 926 P+P P ++ + P T +TP P T P T P TT PI T Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI-STTTTP 1464 Query: 927 APVPSPAPPPEAPRGLGASPS 947 P +P+PP P +PS Sbjct: 1465 PPTTTPSPPTTTPSPPTTTPS 1485 Score = 35.0 bits (79), Expect = 0.34 Identities = 36/141 (25%), Positives = 47/141 (33%), Gaps = 9/141 (6%) Query: 111 SPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGA 170 +P PP P P + PP + T + P T P P T P Sbjct: 1398 TPSPP-TTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456 Query: 171 PPDEVYLSDSPAEPAPTIPGPPSQGDS-RVSSPSWEDGAALQPPPAEALLLP-HGPLRPG 228 P +S + P T P PP+ S ++PS PPP P P+ P Sbjct: 1457 P-----ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP- 1510 Query: 229 PHLIPMVGPVPHPVAEDLTTT 249 P + P P TTT Sbjct: 1511 PASTTTLPPTTTPSPPTTTTT 1531 Score = 35.0 bits (79), Expect = 0.34 Identities = 39/158 (24%), Positives = 52/158 (32%), Gaps = 30/158 (18%) Query: 92 PVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQ 151 P +PSP +P +P PP P P + SPP S + P T Sbjct: 1418 PTTTPSPPTTTTTTPPPTTTPSPPITTTTTP-PPTTTPSPPIST-------TTTPPPTTT 1469 Query: 152 EKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQ 211 P T P+PP + +P+ P T PP ++PS + Sbjct: 1470 PSPPT------TTPSPP---------TTTPSPPTTTTTTPPP-----TTTPSPPTTTPIT 1509 Query: 212 PPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTT 249 PP + L P P P P P TTT Sbjct: 1510 PPASTTTLPP--TTTPSPPTTTTTTPPPTTTPSPPTTT 1545 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.130 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,922,473 Number of Sequences: 37866 Number of extensions: 4388463 Number of successful extensions: 74432 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 661 Number of HSP's successfully gapped in prelim test: 2471 Number of HSP's that attempted gapping in prelim test: 24453 Number of HSP's gapped (non-prelim): 28961 length of query: 977 length of database: 18,247,518 effective HSP length: 112 effective length of query: 865 effective length of database: 14,006,526 effective search space: 12115644990 effective search space used: 12115644990 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.