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Search of human proteins with 157311635
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157311635 FAM83H [Homo sapiens]
(1179 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157311635 FAM83H [Homo sapiens] 2379 0.0
gi|61676089 hypothetical protein LOC222584 [Homo sapiens] 259 1e-68
gi|30425394 hypothetical protein LOC128876 [Homo sapiens] 188 3e-47
gi|153251792 hypothetical protein LOC54854 [Homo sapiens] 184 6e-46
gi|115392150 hypothetical protein LOC644815 [Homo sapiens] 179 2e-44
gi|116235448 hypothetical protein LOC81610 [Homo sapiens] 173 8e-43
gi|40254997 hypothetical protein LOC84985 isoform a [Homo sapiens] 170 8e-42
gi|156564372 hypothetical protein LOC113828 [Homo sapiens] 167 5e-41
gi|46255017 hypothetical protein LOC84985 isoform b [Homo sapiens] 166 2e-40
gi|157785645 SPEG complex locus [Homo sapiens] 57 1e-07
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 54 9e-07
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 52 3e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 52 3e-06
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 51 6e-06
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 50 1e-05
gi|145199237 transcription elongation factor B polypeptide 3 bin... 50 2e-05
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 49 3e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni... 49 3e-05
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 48 6e-05
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 48 6e-05
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 47 1e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 46 2e-04
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 46 2e-04
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 46 2e-04
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 46 2e-04
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens] 46 2e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 45 3e-04
gi|119508426 alpha 3 type IX collagen [Homo sapiens] 45 3e-04
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 45 4e-04
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 45 4e-04
>gi|157311635 FAM83H [Homo sapiens]
Length = 1179
Score = 2379 bits (6166), Expect = 0.0
Identities = 1179/1179 (100%), Positives = 1179/1179 (100%)
Query: 1 MARRSQSSSQGDNPLAPGYLPPHYKEYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEE 60
MARRSQSSSQGDNPLAPGYLPPHYKEYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEE
Sbjct: 1 MARRSQSSSQGDNPLAPGYLPPHYKEYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEE 60
Query: 61 LEHVSRHLRPPQYVTREPPEGSLLDVDMDGSSGTYWPVNSDQAVPELDLGWPLTFGFQGT 120
LEHVSRHLRPPQYVTREPPEGSLLDVDMDGSSGTYWPVNSDQAVPELDLGWPLTFGFQGT
Sbjct: 61 LEHVSRHLRPPQYVTREPPEGSLLDVDMDGSSGTYWPVNSDQAVPELDLGWPLTFGFQGT 120
Query: 121 EVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARRVPVYIL 180
EVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARRVPVYIL
Sbjct: 121 EVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARRVPVYIL 180
Query: 181 LDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAVV 240
LDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAVV
Sbjct: 181 LDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAVV 240
Query: 241 MSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVPSAAALARMDAYALA 300
MSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVPSAAALARMDAYALA
Sbjct: 241 MSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVPSAAALARMDAYALA 300
Query: 301 PYAGAGPLVGVPGVGAPTPFSFPKRAHLLFPPPREEGLGFPSFLDPDRHFLSAFRREEPP 360
PYAGAGPLVGVPGVGAPTPFSFPKRAHLLFPPPREEGLGFPSFLDPDRHFLSAFRREEPP
Sbjct: 301 PYAGAGPLVGVPGVGAPTPFSFPKRAHLLFPPPREEGLGFPSFLDPDRHFLSAFRREEPP 360
Query: 361 RMPGGALEPHAGLRPLSRRLEAEAGPAGELAGARGFFQARHLEMDAFKRHSFATEGAGAV 420
RMPGGALEPHAGLRPLSRRLEAEAGPAGELAGARGFFQARHLEMDAFKRHSFATEGAGAV
Sbjct: 361 RMPGGALEPHAGLRPLSRRLEAEAGPAGELAGARGFFQARHLEMDAFKRHSFATEGAGAV 420
Query: 421 ENFAAARQVSRQTFLSHGDDFRFQTSHFHRDQLYQQQYQWDPQLTPARPQGLFEKLRGGR 480
ENFAAARQVSRQTFLSHGDDFRFQTSHFHRDQLYQQQYQWDPQLTPARPQGLFEKLRGGR
Sbjct: 421 ENFAAARQVSRQTFLSHGDDFRFQTSHFHRDQLYQQQYQWDPQLTPARPQGLFEKLRGGR 480
Query: 481 AGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDPAFAPGPRGLEPSGAP 540
AGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDPAFAPGPRGLEPSGAP
Sbjct: 481 AGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDPAFAPGPRGLEPSGAP 540
Query: 541 RPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDGGDDGL 600
RPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDGGDDGL
Sbjct: 541 RPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDGGDDGL 600
Query: 601 PAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGPEEP 660
PAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGPEEP
Sbjct: 601 PAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGPEEP 660
Query: 661 GLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHKEQTVSETLG 720
GLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHKEQTVSETLG
Sbjct: 661 GLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHKEQTVSETLG 720
Query: 721 PGGEAVRSAASTKVAELLEKYKGPARDPGGGAGAITVASHSKAVVSQAWREEVAAPGAVG 780
PGGEAVRSAASTKVAELLEKYKGPARDPGGGAGAITVASHSKAVVSQAWREEVAAPGAVG
Sbjct: 721 PGGEAVRSAASTKVAELLEKYKGPARDPGGGAGAITVASHSKAVVSQAWREEVAAPGAVG 780
Query: 781 GERRSLESCLLDLRDSFAQQLHQEAERQPGAASLTAAQLLDTLGRSGSDRLPSRFLSAQS 840
GERRSLESCLLDLRDSFAQQLHQEAERQPGAASLTAAQLLDTLGRSGSDRLPSRFLSAQS
Sbjct: 781 GERRSLESCLLDLRDSFAQQLHQEAERQPGAASLTAAQLLDTLGRSGSDRLPSRFLSAQS 840
Query: 841 HSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIEQ 900
HSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIEQ
Sbjct: 841 HSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIEQ 900
Query: 901 KGSPTSAYPERRGSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPME 960
KGSPTSAYPERRGSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPME
Sbjct: 901 KGSPTSAYPERRGSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPME 960
Query: 961 VLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESPRRLSLGQGDSTEAATEERGPR 1020
VLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESPRRLSLGQGDSTEAATEERGPR
Sbjct: 961 VLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESPRRLSLGQGDSTEAATEERGPR 1020
Query: 1021 ARLSSATANALYSSNLRDDTKAILEQISAHGQKHRAVPAPSPGPTHNSPELGRPPAAGVL 1080
ARLSSATANALYSSNLRDDTKAILEQISAHGQKHRAVPAPSPGPTHNSPELGRPPAAGVL
Sbjct: 1021 ARLSSATANALYSSNLRDDTKAILEQISAHGQKHRAVPAPSPGPTHNSPELGRPPAAGVL 1080
Query: 1081 APDMSDKDKCSAIFRSDSLGTQGRLSRTLPASAEERDRLLRRMESMRKEKRVYSRFEVFC 1140
APDMSDKDKCSAIFRSDSLGTQGRLSRTLPASAEERDRLLRRMESMRKEKRVYSRFEVFC
Sbjct: 1081 APDMSDKDKCSAIFRSDSLGTQGRLSRTLPASAEERDRLLRRMESMRKEKRVYSRFEVFC 1140
Query: 1141 KKEEASSPGAGEGPAEEGTRDSKVGKFVPKILGTFKSKK 1179
KKEEASSPGAGEGPAEEGTRDSKVGKFVPKILGTFKSKK
Sbjct: 1141 KKEEASSPGAGEGPAEEGTRDSKVGKFVPKILGTFKSKK 1179
>gi|61676089 hypothetical protein LOC222584 [Homo sapiens]
Length = 1011
Score = 259 bits (661), Expect = 1e-68
Identities = 138/292 (47%), Positives = 182/292 (62%), Gaps = 7/292 (2%)
Query: 1 MARRSQSSSQGDNPLAPGYLPPHYKEYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEE 60
M S SS D + Y+ PHYKE+YR+A+D L E G EAY FL E DFL EE
Sbjct: 1 METSSMLSSLNDECKSDNYIEPHYKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEE 60
Query: 61 LEHVSRHLRPPQYVTREPPEGSLLDVDMDGSSGTYWPVNSDQAVPELDLGWPLTFG--FQ 118
+ ++ +++ Q V + G+ D SSGTYWPV SD P LDLGWP
Sbjct: 61 INYILKNV---QKVAQSTAHGTDDSCDDTLSSGTYWPVESDVEAPNLDLGWPYVMPGLLG 117
Query: 119 GTEVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARRVPVY 178
GT + L PP +IK+ R+MI+ A++V+A+VMD+FTDVD+ E++EA+ R V VY
Sbjct: 118 GTHIDLLFHPPRAHLLTIKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEASTRGVSVY 177
Query: 179 ILLDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCA 238
ILLDE N HFL+M +K ++ + +RVRTV G Y +TG F G +++KFLLVDC
Sbjct: 178 ILLDESNFNHFLNMTEKQGCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQ 237
Query: 239 VVMSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVPSAAA 290
VM GSYS+MWSFEK H S+ + G+LV SFDEEFR L+A+S VPS+ A
Sbjct: 238 KVMYGSYSYMWSFEKAHLSMVQIITGQLVESFDEEFRTLYARS--CVPSSFA 287
Score = 45.4 bits (106), Expect = 3e-04
Identities = 51/213 (23%), Positives = 85/213 (39%), Gaps = 21/213 (9%)
Query: 944 ESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESPRRLS 1003
ES K +++ G L+KGS +LR LLS +++ + + ++P
Sbjct: 750 ESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKK----------ENLSKNKAPAFYR 799
Query: 1004 LGQGDSTEAATEERGPRARLSSATANALYSSNLRDDTKAILEQISAHGQKHRAVPAPSPG 1063
L T + E + + S + SS R + + Q S H K +PS
Sbjct: 800 LCSSSDTLVSEGEENQKPKKSDTKVD---SSPRRKHSSSSNSQGSIHKSKEDVTVSPSQE 856
Query: 1064 PTHNSPELGRPPAAGVLAPDMSDKDKCSAIFRSDSLGTQGRLSRTLPA--------SAEE 1115
E R P+ G + ++ ++ R ++ Q R SR + A ++
Sbjct: 857 INAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPERRPTSSP 916
Query: 1116 RDRLLRRMESMRKEKRVYSRFEVFCKKEEASSP 1148
R + S ++RVYSRFE FCK E + P
Sbjct: 917 RPTSSELLRSHSTDRRVYSRFEPFCKIESSIQP 949
>gi|30425394 hypothetical protein LOC128876 [Homo sapiens]
Length = 747
Score = 188 bits (477), Expect = 3e-47
Identities = 117/303 (38%), Positives = 172/303 (56%), Gaps = 12/303 (3%)
Query: 24 YKEYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEELEHVSRHLRP-PQYVTREPPEGS 82
+ E RLA DAL E G AY R ++ E FL ++++++ H+R P+ + E S
Sbjct: 41 HSEAARLAADALLERGEAAYLRVISEERELPFLSALDVDYMTSHVRGGPELSEAQGQEAS 100
Query: 83 ---LLDVDMDGSSGTYWPVNSDQAVPELDLGWP---LTFGFQGTEVTTLVQPPPPDSPSI 136
L + + +SGTY+P+ SD P+LDLGWP GF T+ Q + +I
Sbjct: 101 GPDRLSLLSEVTSGTYFPMASDIDPPDLDLGWPEVPQATGFSPTQAVVHFQRDK--AKNI 158
Query: 137 KDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARR-VPVYILLDEMNAQHFLDMADK 195
KD R + A VVAVVMD+FTD++LL +++EA++RR VPVY+LL + + +HFL+M K
Sbjct: 159 KDLLRFLFSQAHTVVAVVMDIFTDMELLCDLMEASSRRGVPVYLLLAQEHLRHFLEMCYK 218
Query: 196 CRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAVVMSGSYSFMWSFEKIH 255
+N H+ +RVR+ G TY + G+ F G EKF+L+DC V++GSYSF W + H
Sbjct: 219 MDLNGEHLPNMRVRSTCGDTYCSKAGRRFTGQALEKFVLIDCEQVVAGSYSFTWLCSQAH 278
Query: 256 RSLAHVFQGELVSSFDEEFRILFAQSEPLVPSAAALARMDAYALAPYAGAGPLVGVPGVG 315
S+ +G +V FD EFR L+A+S+P+ + AL P A L P V
Sbjct: 279 TSMVLQLRGRIVEDFDREFRCLYAESQPVEGFCGGEDPLSPRALRPPPVA--LAFRPDVP 336
Query: 316 APT 318
+PT
Sbjct: 337 SPT 339
>gi|153251792 hypothetical protein LOC54854 [Homo sapiens]
Length = 478
Score = 184 bits (466), Expect = 6e-46
Identities = 110/277 (39%), Positives = 162/277 (58%), Gaps = 9/277 (3%)
Query: 16 APGYLPPHYKEYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEELEHVSRHLRPPQYVT 75
+PG+L Y E RLA++AL G+EA+ + E FL +E++ ++
Sbjct: 22 SPGFL---YSEGQRLALEALLSKGAEAFQTCVQREELWPFLSADEVQGLAAAAEDWTVAK 78
Query: 76 REPP---EGSLLDVDMDGSSGTYWPVNSDQAVPELDLGWPLTFGFQG-TEVTTLVQPPPP 131
+EP EG+ D+D S +YWP S+Q P L LGWP+ ++G T QPP
Sbjct: 79 QEPSGMAEGATT-TDVDAGSLSYWPGQSEQPAPVLRLGWPVDSAWKGITRAQLYTQPPGE 137
Query: 132 DSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARR-VPVYILLDEMNAQHFL 190
P +K+ R I++A ++VAVVMD+FTD DLL ++++AA RR VPVY+LLD FL
Sbjct: 138 GQPPLKELVRLEIQAAHKLVAVVMDVFTDPDLLLDLVDAATRRWVPVYLLLDRQQLPAFL 197
Query: 191 DMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAVVMSGSYSFMWS 250
++A + VN + + + VR V G ++ R + G V+EKF+L+D V+SGSYSF WS
Sbjct: 198 ELAQQLGVNPWNTENVDVRVVRGCSFQSRWRRQVSGTVREKFVLLDGERVISGSYSFTWS 257
Query: 251 FEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVPS 287
++HR L + GE+V +F EFR L+A S PL P+
Sbjct: 258 DARLHRGLVTLLTGEIVDAFSLEFRTLYAASCPLPPA 294
>gi|115392150 hypothetical protein LOC644815 [Homo sapiens]
Length = 823
Score = 179 bits (453), Expect = 2e-44
Identities = 103/282 (36%), Positives = 158/282 (56%), Gaps = 25/282 (8%)
Query: 24 YKEYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEELEHVSRHLRPPQYVTREP----- 78
Y E RLA++AL G +A+ L E DFL EL+ + + + +P
Sbjct: 27 YSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRILETIEVYDPGSEDPRGTGP 86
Query: 79 ---PEGSLLDVDMDGSSGT--------------YWPVNSDQAVPELDLGWPLTFGFQG-T 120
PE + + D + +SG YWP SD+++P+LDLGWP T ++G T
Sbjct: 87 SQGPEDNGVG-DGEEASGADGVPIEAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVT 145
Query: 121 EVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAA-ARRVPVYI 179
+ +QPP IK+ R+MI AQ+V+AVVMDMFTDVD+ ++L+A R+V VYI
Sbjct: 146 RASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYI 205
Query: 180 LLDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAV 239
++DE N ++FL M ++ ++L H+ LRVR+ G ++ R+ FKG + +KF+ VD
Sbjct: 206 IVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRSATKFKGALAQKFMFVDGDR 265
Query: 240 VMSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQS 281
+ GSYSF WS + R++ V G++V FD +F+ L+ S
Sbjct: 266 AVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMS 307
Score = 32.3 bits (72), Expect = 2.7
Identities = 61/276 (22%), Positives = 95/276 (34%), Gaps = 45/276 (16%)
Query: 855 EGSGAHQVLHN--ESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERR 912
+ S HQ+ +S+ P P +P G G P +G P
Sbjct: 454 QASAQHQLWKQSQDSRPRPEPCPPPEPSAPQDGVPAENGLP-------QGDP-------- 498
Query: 913 GSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPM-EVLRKGSLRLRQ 971
P+PPVP+ R+ PV V R S + E PK + G + + G L++
Sbjct: 499 -EPLPPVPKPRTVPVADVLARDSS-DIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQR 556
Query: 972 LLSPKGERRMEDEGGFPVPQENGQPESPRRLSLGQGDSTEAATEERGPRARLSSATANAL 1031
LS + G P + + E + + + RGP R S
Sbjct: 557 QLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSV----- 611
Query: 1032 YSSNLRDDTKAILEQISAHGQKHRAVPAPSPGPTHNSPELGRPPAAGVLAPDMSDKDKCS 1091
+S++ ++ + E ++H A P P PP + AP
Sbjct: 612 -ASSVSEEYFEVREHSVPLRRRHSEQVANGPTP---------PPRRQLSAPH-------- 653
Query: 1092 AIFRSDSLGTQGRLSRTLPASAEERDRLLRRMESMR 1127
I R +G QG EE D L+RM++ R
Sbjct: 654 -ITRGTFVGPQGGSPWAQSRGREEAD-ALKRMQAQR 687
>gi|116235448 hypothetical protein LOC81610 [Homo sapiens]
Length = 615
Score = 173 bits (439), Expect = 8e-43
Identities = 111/287 (38%), Positives = 154/287 (53%), Gaps = 17/287 (5%)
Query: 13 NPLAPGYLPPHYKEYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEELEHVSRHLRPP- 71
+P P + E RLA++ L GG EA++ FL E FL P+E+ + R P
Sbjct: 47 SPCGPPNPTELFSESRRLALEELVAGGPEAFAAFLRRERLARFLNPDEVHAILRAAERPG 106
Query: 72 -----QYVTREPPEGSLLDVDMDGSSGTYWPVNSDQAVPELDLGWPLTF--GFQG-TEVT 123
E GS D SSGTY+P SD P L+LGWP + ++G T V
Sbjct: 107 EEGAAAAAAAEDSFGS----SHDCSSGTYFPEQSDLEPPLLELGWPAFYQGAYRGATRVE 162
Query: 124 TLVQPPPPDSPS---IKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARR-VPVYI 179
T QP KD R+ +RSA++V+AVVMD+FTD+D+ ++ E ++ V VYI
Sbjct: 163 THFQPRGAGEGGPYGCKDALRQQLRSAREVIAVVMDVFTDIDIFRDLQEICRKQGVAVYI 222
Query: 180 LLDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAV 239
LLD+ FLDM +V+ + VRT+ G YY R+G G V EKF L+D
Sbjct: 223 LLDQALLSQFLDMCMDLKVHPEQEKLMTVRTITGNIYYARSGTKIIGKVHEKFTLIDGIR 282
Query: 240 VMSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVP 286
V +GSYSF W+ K++ S + G++V FD EFRIL+AQS+P+ P
Sbjct: 283 VATGSYSFTWTDGKLNSSNLVILSGQVVEHFDLEFRILYAQSKPISP 329
>gi|40254997 hypothetical protein LOC84985 isoform a [Homo sapiens]
Length = 434
Score = 170 bits (430), Expect = 8e-42
Identities = 130/410 (31%), Positives = 192/410 (46%), Gaps = 60/410 (14%)
Query: 26 EYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEELEHVSRHLRPPQYVTREPPEGSLLD 85
E RLA DAL +GGSEAY R L+ EG DFL E +++ R P
Sbjct: 33 ESARLATDALLDGGSEAYWRVLSQEGEVDFLSSVEAQYIQAQAREPPCPPDTLGGAEAGP 92
Query: 86 VDMDGSS---GTYWPVNSDQAVPELDLGWPLT---FGFQGTEVTTLVQPPPPDSPSIKDE 139
+D SS GTY+PV S+ + P L W + + + T Q ++ I+D
Sbjct: 93 KGLDSSSLQSGTYFPVASEGSEPALLHSWASAEKPYLKEKSSATVYFQTVKHNN--IRDL 150
Query: 140 ARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARR-VPVYILLDEMNAQHFLDMADKCRV 198
RR I QV+ ++MD+FTDV++ ++LEAA +R V V +LLD+ + F +M DK ++
Sbjct: 151 VRRCITRTSQVLVILMDVFTDVEIFCDILEAANKRGVFVCVLLDQGGVKLFQEMCDKVQI 210
Query: 199 NLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAVVMSGSYSFMWSFEKIHRSL 258
+ H+ + +R+V G Y ++G+ F G ++EKF++ D V+SGSYSF W +HR++
Sbjct: 211 SDSHLKNISIRSVEGEIYCAKSGRKFAGQIREKFIISDWRFVLSGSYSFTWLCGHVHRNI 270
Query: 259 AHVFQGELVSSFDEEFRILFAQSEPL-----------VPSAAALAR----------MDAY 297
F G+ V FDEEFR L+A S+P+ VP AA A D
Sbjct: 271 LSKFTGQAVELFDEEFRHLYASSKPVMGLKSPRLVAPVPPGAAPANGRLSSSSGSASDRT 330
Query: 298 ALAPYAG--AGPLVGVPGVGAPTPFSFPKRAHLLFPPPREEGLGFPSFLDPDRHFLSAFR 355
+ P++G AG G V A + P H PPP
Sbjct: 331 SSNPFSGRSAGSHPGTRSVSASSGPCSPAAPH---PPPPP-------------------- 367
Query: 356 REEPPRMPGGALEPHAGLRPLSRRLEAEAGPAGELAGARGFFQARHLEMD 405
R +P + P GA P A L P GP + G ++ L+++
Sbjct: 368 RFQPHQGPWGAPSPQAHLSP-----RPHDGPPAAVYSNLGAYRPTRLQLE 412
>gi|156564372 hypothetical protein LOC113828 [Homo sapiens]
Length = 500
Score = 167 bits (423), Expect = 5e-41
Identities = 103/272 (37%), Positives = 147/272 (54%), Gaps = 13/272 (4%)
Query: 23 HYKEYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEELEHVSRHLRPPQYV-------- 74
+Y E R A++AL GG +AY L E DFL E + + P +
Sbjct: 26 YYCERRRAALEALLGGGEQAYRERLKEEQLRDFLSSPERQALRAAWSPYEDAVPAANARG 85
Query: 75 -TREPPEGSLLDVDMDGSSGTYWPVNSDQAVPELDLGWPLTFGFQGTEVTTLVQPPPPD- 132
++ + G S YWP SD VP LDLGW T ++G TL PP D
Sbjct: 86 KSKAKAKAPAPAPAESGESLAYWPDRSDTEVPPLDLGWTDTGFYRGVSRVTLFTHPPKDE 145
Query: 133 -SPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAA-RRVPVYILLDEMNAQHFL 190
+P +K R+MI+ AQ+V+AVVMD+FTD D+ ++++AA RRVPVYI+LDE ++FL
Sbjct: 146 KAPHLKQVVRQMIQQAQKVIAVVMDLFTDGDIFQDIVDAACKRRVPVYIILDEAGVKYFL 205
Query: 191 DMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAVVMSGSYSFMWS 250
+M ++ + +RVR+V G +Y G+ KG + +FL+VD V +GSY F WS
Sbjct: 206 EMCQDLQLTDFRIRNIRVRSVTGVGFYMPMGR-IKGTLSSRFLMVDGDKVATGSYRFTWS 264
Query: 251 FEKIHRSLAHVFQGELVSSFDEEFRILFAQSE 282
+ R+L + G+ V FD EFR L+A SE
Sbjct: 265 SSHVDRNLLLLLTGQNVEPFDTEFRELYAISE 296
>gi|46255017 hypothetical protein LOC84985 isoform b [Homo sapiens]
Length = 367
Score = 166 bits (419), Expect = 2e-40
Identities = 99/267 (37%), Positives = 150/267 (56%), Gaps = 9/267 (3%)
Query: 26 EYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEELEHVSRHLRPPQYVTREPPEGSLLD 85
E RLA DAL +GGSEAY R L+ EG DFL E +++ R P
Sbjct: 33 ESARLATDALLDGGSEAYWRVLSQEGEVDFLSSVEAQYIQAQAREPPCPPDTLGGAEAGP 92
Query: 86 VDMDGSS---GTYWPVNSDQAVPELDLGWPLT---FGFQGTEVTTLVQPPPPDSPSIKDE 139
+D SS GTY+PV S+ + P L W + + + T Q ++ I+D
Sbjct: 93 KGLDSSSLQSGTYFPVASEGSEPALLHSWASAEKPYLKEKSSATVYFQTVKHNN--IRDL 150
Query: 140 ARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARR-VPVYILLDEMNAQHFLDMADKCRV 198
RR I QV+ ++MD+FTDV++ ++LEAA +R V V +LLD+ + F +M DK ++
Sbjct: 151 VRRCITRTSQVLVILMDVFTDVEIFCDILEAANKRGVFVCVLLDQGGVKLFQEMCDKVQI 210
Query: 199 NLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAVVMSGSYSFMWSFEKIHRSL 258
+ H+ + +R+V G Y ++G+ F G ++EKF++ D V+SGSYSF W +HR++
Sbjct: 211 SDSHLKNISIRSVEGEIYCAKSGRKFAGQIREKFIISDWRFVLSGSYSFTWLCGHVHRNI 270
Query: 259 AHVFQGELVSSFDEEFRILFAQSEPLV 285
F G+ V FDEEFR L+A S+P++
Sbjct: 271 LSKFTGQAVELFDEEFRHLYASSKPVM 297
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 56.6 bits (135), Expect = 1e-07
Identities = 132/558 (23%), Positives = 192/558 (34%), Gaps = 99/558 (17%)
Query: 626 LPSAFRVPAAFPTKV----PVPGPGSGGNGPEREGPEEPGLAKQDSFRSRLNPLVQRSSR 681
+P R P P +V P P SGG + EE + + S PL S
Sbjct: 1893 IPELLRAP---PERVWVTMPRRPPPSGGLSSSSDSEEE----ELEELPSVPRPLQPEFSG 1945
Query: 682 LRSSL--IFSTSQAEGAAGAAAATE-------KVQLLHKEQTVSETLGPGGEAVRSAAST 732
R SL I + +A G AAT + +E E L G+ + AS
Sbjct: 1946 SRVSLTDIPTEDEALGTPETGAATPMDWQEQGRAPSQDQEAPSPEALPSPGQEPAAGASP 2005
Query: 733 KVAELLEKYKGPARDPGGGAGAITVASHSKAVVSQAWREEVAAPGAVGGERRSLESCLLD 792
+ EL + P G + H A V R +PGA R L
Sbjct: 2006 RRGELRRGSSAESALPRAGPRELGRGLHKAASVELPQRRS-PSPGATRLARGGLGE---- 2060
Query: 793 LRDSFAQQLHQEAER------QPGAASLTAAQLLDTLGRSGSDRLPSRFLSA-------- 838
+AQ+L +R + G S LL++LG D +R S+
Sbjct: 2061 --GEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLESLGGRARDPRMARAASSEAAPHHQP 2118
Query: 839 -------QSHSTSPQGLDSP------------LPLEGSGAHQVLHNESKGSPTSAYPE-- 877
Q S+ QG P +P+ GA ++ + S + + A P
Sbjct: 2119 PLENRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSSP 2178
Query: 878 -RKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVP-PVPERRSSPVPPVPERRG 935
R +P P + + P+ P + P + +P P P P R S P PP P+
Sbjct: 2179 ARPSAPKPS-TPKSAEPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPP-PQALQ 2236
Query: 936 SLTLTIS--------------GESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKG--ER 979
+L L ++ + P GPA + P E ++ R P G E+
Sbjct: 2237 TLALPLTPYAQIIQSLQLSGHAQGPSQGPA----APPSEPKPHAAVFARVASPPPGAPEK 2292
Query: 980 RMEDEGGFPVPQENGQ-PESPRRLSLGQGDS-----TEAATEERGPRARLSSATANALYS 1033
R+ GG PV E + P P R S +EA E + R+R S +
Sbjct: 2293 RVPSAGGPPVLAEKARVPTVPPRPGSSLSSSIENLESEAVFEAKFKRSRESPLSLGLRLL 2352
Query: 1034 SNLRDDTKAILEQISAHGQKHRAVPAPSPGPTHNSPELGRPPAAGVLAPDMSDKDKCSAI 1093
S R + + +R PA +P EL R P D+ + +
Sbjct: 2353 SRSRSEERGPFRGAEEEDGIYRPSPAGTP------LELVRRPERSRSVQDLRAVGE-PGL 2405
Query: 1094 FRSDSLGTQGRLSRTLPA 1111
R SL RL RT PA
Sbjct: 2406 VRRLSLSLSQRLRRTPPA 2423
Score = 35.0 bits (79), Expect = 0.42
Identities = 170/700 (24%), Positives = 232/700 (33%), Gaps = 144/700 (20%)
Query: 264 GELVSSFD---EEFRILFAQSEPLVPSAAALARMDAYALAPYAGAGPLVGVPGVGAPTPF 320
G L SS D EE L + PL P + +L +G P GA TP
Sbjct: 1916 GGLSSSSDSEEEELEELPSVPRPLQPEFSG----SRVSLTDIPTEDEALGTPETGAATPM 1971
Query: 321 SFPKRAHLLFPPPREEGLGFPSFLDPDRHFLSAFRREEPPRMPGGALEPHAGLRPLSRRL 380
+ ++ P +E PS P +P EP AG P RR
Sbjct: 1972 DWQEQGRA--PSQDQEA---PS----------------PEALPSPGQEPAAGASP--RRG 2008
Query: 381 EAEAGPAGELAG--------ARGFFQARHLEMDAFKRHS-----FATEGAGAVENFAAAR 427
E G + E A RG +A +E+ + S A G G E +A
Sbjct: 2009 ELRRGSSAESALPRAGPRELGRGLHKAASVELPQRRSPSPGATRLARGGLGEGE-YAQRL 2067
Query: 428 QVSRQTFLSHGDDF----------------RFQTSHFHRDQLYQQQYQWDPQLTPARPQG 471
Q RQ L G + R + R + P P +G
Sbjct: 2068 QALRQRLLRGGPEDGKVSGLRGPLLESLGGRARDPRMARAASSEAAPHHQP---PLENRG 2124
Query: 472 LFEKLRGGRAGFADPDDFTLGAG-PRFPELGPDGHQRLDYVPSSASREVRHGSDPA--FA 528
L +K G A+P AG P + G +RL PS ++ S PA A
Sbjct: 2125 L-QKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSSPARPSA 2183
Query: 529 PGP---RGLEPSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRL-- 583
P P + EPS + Q Q A P+P PE + P +A L+ L
Sbjct: 2184 PKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQA-LQTLALPL 2242
Query: 584 --------ASYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAG---DLLPSAFRV 632
+ LSG H + G G AP V A P G +PSA
Sbjct: 2243 TPYAQIIQSLQLSG-HAQ-GPSQGPAAPPSEPKPHAAVFARVASPPPGAPEKRVPSAGGP 2300
Query: 633 PA-AFPTKVPVPGPGSGGN-GPEREGPEEPGLAKQDSFRSRLNPL---VQRSSRLRSSLI 687
P A +VP P G + E E + + RSR +PL ++ SR RS
Sbjct: 2301 PVLAEKARVPTVPPRPGSSLSSSIENLESEAVFEAKFKRSRESPLSLGLRLLSRSRSEER 2360
Query: 688 FSTSQAEGAAG------AAAATEKVQLLHKEQTVSETLGPGGEAVRSAASTKVAELLEK- 740
AE G A E V+ + ++V + G + S +++ L +
Sbjct: 2361 GPFRGAEEEDGIYRPSPAGTPLELVRRPERSRSVQDLRAVGEPGLVRRLSLSLSQRLRRT 2420
Query: 741 ---YKGPARDPGGGAGAITVASHSKAVVSQAWREEVAAPGAVGGERRSLESCLLDLRDSF 797
+ PA + GG G + S A V RR L L L
Sbjct: 2421 PPAQRHPAWEARGGDGESSEGGSS------------ARGSPVLAMRRRLSFTLERLSSRL 2468
Query: 798 AQQLHQEAERQPGAASLTAAQLLDTLGRSGSD-------RLPSRFLSAQSHSTSPQGLDS 850
+ E G AS + L L R+ S+ LP L+AQ+ +T+P
Sbjct: 2469 QRSGSSE---DSGGASGRSTPLFGRLRRATSEGESLRRLGLPHNQLAAQAGATTPSA--- 2522
Query: 851 PLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRR 890
ES GS SA GS PG S R
Sbjct: 2523 ---------------ESLGSEASA---TSGSSAPGESRSR 2544
Score = 31.6 bits (70), Expect = 4.7
Identities = 103/405 (25%), Positives = 142/405 (35%), Gaps = 88/405 (21%)
Query: 617 GGRAPAGDLLPSAFRVPAAFPT----KVPVPGPGSGGNGPEREGPEE----PGLAKQDSF 668
G R+P G P A PAA PT + P E+ G + P LA
Sbjct: 317 GKRSPPG---PPA--QPAATPTSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAES 371
Query: 669 RSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHKEQTVSETLGPGGEAVRS 728
R + PL + S RL + S AG+ +K+Q + + E +R
Sbjct: 372 RPQ-TPLSEASGRLSA---LGRSPRLVRAGSRIL-DKLQFFEERRRSLERSDSPPAPLRP 426
Query: 729 AASTKVAELLEKYKGPARDPGGGAGAITVASHSKAVVSQAWREEVAAPGAVGGERRSLE- 787
+ A LE+ K P G GA +EE+ APG+V RR +
Sbjct: 427 WVPLRKARSLEQPKSERGAPWGTPGAS--------------QEELRAPGSVAERRRLFQQ 472
Query: 788 ------------SCLLDLRDSFAQQLHQEAERQPGAASLTAAQ--LLDTLGRSGSDRLPS 833
S DL FAQ+L + R L + L TL R+ S R P
Sbjct: 473 KAASLDERTRQRSPASDLELRFAQELGR-IRRSTSREELVRSHESLRATLQRAPSPREPG 531
Query: 834 R-------FLSAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPG- 885
S + SP P P S A + + G P S P + P G
Sbjct: 532 EPPLFSRPSTPKTSRAVSPAAAQPPSP---SSAEKP--GDEPGRPRSRGPAGRTEPGEGP 586
Query: 886 ---FSTRRGSPTTGF--IEQKGSPT---SAYPERRGSPVPPVPERRSSPVPPV------- 930
R P T I++ SP +A P + PP +R P V
Sbjct: 587 QQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEARTKAPP-GRKREPPAQAVRFLPWAT 645
Query: 931 PERRGSL---TLTISGESPKA------GPAEEGPSGPMEVLRKGS 966
P G+ TL + P+A GP E+GP GP + R+G+
Sbjct: 646 PGLEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWD--RRGA 688
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 53.9 bits (128), Expect = 9e-07
Identities = 142/607 (23%), Positives = 197/607 (32%), Gaps = 116/607 (19%)
Query: 525 PAFAPGPRGLEPSGAPRPNLTQRFPCQAAARPGPDPA-PEAEPERRGGPEGRAGLRRWRL 583
PA AP P S PR T+ P P P A P A P R P +
Sbjct: 1519 PAAAPTPTHRRTSAIPRA-FTRERPQGRKEAPAPSKAAPAAPPPARTQPS--------LI 1569
Query: 584 ASYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVP 643
A C+ L P E E + P GR PA TK P P
Sbjct: 1570 ADETPPCYSLSSSASSLSEP---EPSEPPAVHPRGREPA--------------VTKDPGP 1612
Query: 644 GPGSGGNGPEREGPEEPGLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAAT 703
G G + R E + R P+ R + AEG+
Sbjct: 1613 GGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGSR------ 1666
Query: 704 EKVQLLHKEQTVSETLGPGGEAVRSAASTKVAELLEKYKGPARDPGGGAGAITVASHSKA 763
E+ + S+ A++ A++ + L + R+ + +I +
Sbjct: 1667 ERGEEAAGSDRASDLDSVEWRAIQEGANS-IVTWLHQAAAATREASSESDSILSFVSGLS 1725
Query: 764 VVSQAW----REEVAAPGAVGGERRSLESCLLDLRDSFAQQLHQEAERQPGAASLTAAQL 819
V S R+ A G +G RR + ++ S + + E+ G T
Sbjct: 1726 VGSTLQPPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVP 1785
Query: 820 LDTLGRSGSDRLPSRFLSAQSHST----------SPQGLDSP-----LPLEGSGAHQVLH 864
GR+ +PS AQ T +P L P +P G + LH
Sbjct: 1786 AVLRGRTVI-YVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLH 1844
Query: 865 NESKGS--------PTSAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTS----AYPERR 912
+K S P SA P + + TP S+ + SP + + +K P + A P
Sbjct: 1845 RPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPG 1904
Query: 913 GSPVPPVPER---------RSSPV----PPVPERRGSLTLTISGESP--------KAGPA 951
SPVP P R + SPV P RRG L + P +AGP
Sbjct: 1905 ASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGRAGTEAGPG 1964
Query: 952 EEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESP----RRLSLGQG 1007
G R G +R+ LS E D GF Q ESP RR L
Sbjct: 1965 ARGG-------RLGLVRVASALSSGSE--SSDRSGFR-RQLTFIKESPGLRRRRSELSSA 2014
Query: 1008 DSTEAATEERGPRARLSSATANALYSSNLRDDTKAILEQISAHGQKHRAVPAPSPGPTHN 1067
+S +A + PR + A L SS ++ RA P P P
Sbjct: 2015 ESAASAPQGASPRRGRPALPAVFLCSSRC---------------EELRAAPRQGPAPARQ 2059
Query: 1068 SPELGRP 1074
P RP
Sbjct: 2060 RPPAARP 2066
Score = 38.9 bits (89), Expect = 0.029
Identities = 174/740 (23%), Positives = 244/740 (32%), Gaps = 154/740 (20%)
Query: 484 ADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDPAFAPGPRGLEPSGAPRPN 543
A D TL PR GP G QR P+SA + + H A G + GA +
Sbjct: 1404 ASLSDETLQGPPRDQPGGPAGRQRPTGRPTSARQAMGH-RHKAGGAGRSAEQSRGAGKNR 1462
Query: 544 LTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDGGDDGLPAP 603
P RP P A ++ G GR GD L +
Sbjct: 1463 AGLELPL---GRP-----PSAPADKDGSKPGRTR------------------GDGALQSL 1496
Query: 604 MEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGPEEPGLA 663
E+ V G S PAA PT P P E P
Sbjct: 1497 CLTTPTEEAVYCFYGN-------DSDEEPPAAAPT----PTHRRTSAIPRAFTRERPQGR 1545
Query: 664 KQDSFRSRLNPLVQRSSRLRSSLI-------FSTSQAEGAAGAAAATEK--VQLLHKEQT 714
K+ S+ P +R + SLI +S S + + +E V +E
Sbjct: 1546 KEAPAPSKAAPAAPPPARTQPSLIADETPPCYSLSSSASSLSEPEPSEPPAVHPRGREPA 1605
Query: 715 VSETLGPGGEAVRSAASTKVAELLEKYKGPA----RDPGGG----AGAITVASHSKAVVS 766
V++ GPGG S + ELL++ A R P G T A S
Sbjct: 1606 VTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGS 1665
Query: 767 QAWREEVAAPGAVGGERRS-LES----CLLDLRDSFAQQLHQEAERQPGAAS-------- 813
+ EE A G +R S L+S + + +S LHQ A A+S
Sbjct: 1666 RERGEE-----AAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSESDSILSF 1720
Query: 814 LTAAQLLDTL------------GRSGSDRLPSRFLSAQSHST----SPQGLDSPLPLEGS 857
++ + TL G GS R P + +A ++ SP G + P + +
Sbjct: 1721 VSGLSVGSTLQPPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKT 1780
Query: 858 --GAHQVLHN-------------ESKGSPTSAYPERKGS-------------PTPG---- 885
G VL + KG+P RK + P+PG
Sbjct: 1781 TPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRS 1840
Query: 886 FSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPVPERRSSPV-PPVPERRGSLTLTISG- 943
S R + T+ P SA P R + P ++SP P+P +R +T
Sbjct: 1841 RSLHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGAL 1900
Query: 944 ESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESPRRLS 1003
P A P + P+ +L K R + +R G P P PE R
Sbjct: 1901 PGPGASPVPKTPA--RTLLAKQHKTQRSPVRIPFMQRPARRG--PPPLARAVPEPGPRGR 1956
Query: 1004 LGQGDSTEAATEERGPRARLSSATANALYSSNLRDDTKAILEQIS----AHGQKHR---- 1055
G TEA RG R L A+AL S + D Q++ + G + R
Sbjct: 1957 AG----TEAGPGARGGRLGL-VRVASALSSGSESSDRSGFRRQLTFIKESPGLRRRRSEL 2011
Query: 1056 -AVPAPSPGPTHNSPELGRPPAAGVLAPDMSDKDKCSAIFRSDSLGTQGRLSRTLPASAE 1114
+ + + P SP GRP V CS+ R + L R PA A
Sbjct: 2012 SSAESAASAPQGASPRRGRPALPAVFL--------CSS--RCEELRAAPRQG---PAPAR 2058
Query: 1115 ERDRLLRRMESMRKEKRVYS 1134
+R R R +R S
Sbjct: 2059 QRPPAARPSPGERPARRTTS 2078
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 52.4 bits (124), Expect = 3e-06
Identities = 144/566 (25%), Positives = 179/566 (31%), Gaps = 128/566 (22%)
Query: 493 AGPRFPELGPDGHQRLDYVPSSASREVRHG-------SDPAFAPGPRGLEPSGAPRPNLT 545
AG R P GP G + P + G A APG +G SG+P N
Sbjct: 263 AGERGPP-GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG--ESGSPGEN-- 317
Query: 546 QRFPCQAAARPGPDPAPEAEPERRG--GPEGRAGLRRWRLASYLSGCHGEDG--GDDGLP 601
PGP P P RG GP G AG R G DG G G P
Sbjct: 318 --------GSPGP-MGPRGLPGERGRTGPAGAAGAR------------GNDGQPGPAGPP 356
Query: 602 APMEAEAYEDDVLAPGGRA---PAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREG-- 656
P+ APG + P G P + P P PGP P +G
Sbjct: 357 GPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIP 416
Query: 657 -----PEEPGLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHK 711
PG+A F P +GA G
Sbjct: 417 GAKGSAGAPGIAGAPGFPGPRGP----------------PGPQGATG------------- 447
Query: 712 EQTVSETLGPGGEAVRSAASTKVAELLEKYKGPARDPG--GGAGAITVASHSKAVVSQAW 769
LGP G+ + E +GP +PG G GA A +
Sbjct: 448 ------PLGPKGQTGEPGIAGFKGE-----QGPKGEPGPAGPQGAPGPAG------EEGK 490
Query: 770 REEVAAPGAVG-----GERRSLESCLLDLRDSFAQQLHQEAERQP-GAASLTAAQLLDTL 823
R PG VG GER + + +D A ER P G A A
Sbjct: 491 RGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN--GDP 548
Query: 824 GRSGSDRLP-SRFLSAQSHSTSPQGLDSP--LPLEGSGAHQVLHNESKGSP-TSAYPERK 879
GR G LP +R L+ + PQG P P E ++G P +P K
Sbjct: 549 GRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK 608
Query: 880 G-SPTPGFSTRRGSP----TTGFIEQKGSPTSAYPERRGSPVPPVPERRSSPVPPVPERR 934
G + PG + +G P G + G +A P P P ER P +
Sbjct: 609 GANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP---GPAGPAGERGEQGAPGPSGFQ 665
Query: 935 GSLTLTISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENG 994
G P P E G G V G L+ P+GER E G P Q
Sbjct: 666 GL-------PGPPGPPGEGGKPGDQGV--PGEAGAPGLVGPRGERGFPGERGSPGAQ--- 713
Query: 995 QPESPRRLSLGQG-DSTEAATEERGP 1019
+ PR L G D + A+ GP
Sbjct: 714 GLQGPRGLPGTPGTDGPKGASGPAGP 739
Score = 48.9 bits (115), Expect = 3e-05
Identities = 167/678 (24%), Positives = 212/678 (31%), Gaps = 144/678 (21%)
Query: 466 PARPQGLFEKLRGGRAGFADPDDFTLGAGPRFP--ELGPDGHQRLDYVPSSASREVRHGS 523
P P G E+ G GF D AGP+ E GP G P A+ +
Sbjct: 502 PIGPPG--ERGAPGNRGFPGQDGL---AGPKGAPGERGPSGLAG----PKGANGDPGRPG 552
Query: 524 DPAFAPGPRGLE-------------PSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRG 570
+P PG RGL PSGAP + P AR P P+
Sbjct: 553 EPGL-PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611
Query: 571 GPEGRAGLRRWRLASYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAF 630
G G+AG + A L G G+D G+ G P PG PAG+
Sbjct: 612 GEPGKAGEKGLPGAPGLRGLPGKD-GETGAAGP------------PGPAGPAGERGEQGA 658
Query: 631 RVPAAFPTKVPVPG-PGSGGNGPEREGPEE---PGLAKQDSFR----SRLNPLVQRSSRL 682
P+ F PG PG GG ++ P E PGL R R +P Q
Sbjct: 659 PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 718
Query: 683 RSSLIFSTSQAEGAAGA--------AAATEKVQLLHKEQTVSETLGPGGEAVRSAASTKV 734
R + T +G GA A +Q + E+ + GP G+ V
Sbjct: 719 RG--LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD------RGDV 770
Query: 735 AELLEKYKGPARDPG--GGAGAITVASHSKAVVSQAWREEVAAPGAVGGERRSLESCLLD 792
E KGP PG GG G + + EV PG G
Sbjct: 771 GE-----KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS----------- 814
Query: 793 LRDSFAQQLHQEAER----QPGAASLTAAQLLDTLGRSGSDRLPSRFLSAQSHSTSPQGL 848
A ER PG A G G+D P Q +
Sbjct: 815 -----AGARGAPGERGETGPPGPAGFA--------GPPGADGQPGA-KGEQGEAGQKGDA 860
Query: 849 DSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAY 908
+P P SGA PT + G G P G + G P S
Sbjct: 861 GAPGPQGPSGA------PGPQGPTGVTGPKGARGAQGPPGATGFP--GAAGRVGPPGS-- 910
Query: 909 PERRGSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPA----------------E 952
G+P PP P S P R S +GE GPA
Sbjct: 911 ---NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA 967
Query: 953 EGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFP-VPQENGQPESPRRLSLGQGD--- 1008
EGP GP +G R ++ G+R E GFP +P +G+P + GD
Sbjct: 968 EGPPGP-----QGLAGQRGIVGLPGQR---GERGFPGLPGPSGEP-GKQGAPGASGDRGP 1018
Query: 1009 ----STEAATEERGPRARLSSATANALYSSNLRDDTKAILEQISAHGQKHRAVPAPSPGP 1064
T G R S A+ + K + A G P SPGP
Sbjct: 1019 PGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP 1078
Query: 1065 THNSPELGRPPAAGVLAP 1082
+ + G AG P
Sbjct: 1079 AGPTGKQGDRGEAGAQGP 1096
Score = 34.7 bits (78), Expect = 0.55
Identities = 54/202 (26%), Positives = 68/202 (33%), Gaps = 41/202 (20%)
Query: 493 AGPRFPELGPDGHQRLDYVPSSASREVRHGSDPAFAPGPRGLEPSGAPRPNLTQRFPCQA 552
+G R P GP G L RE G+D GP G + + + + + A
Sbjct: 1013 SGDRGPP-GPVGPPGLTGPAGEPGREGSPGAD-----GPPGRDGAAGVKGDRGETGAVGA 1066
Query: 553 AARPGP--DPAPEAEPERRG-----------GPEGRAGLRRWRLASYLSGCHGEDG---- 595
PGP P P ++G GP G AG R + G GE G
Sbjct: 1067 PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1126
Query: 596 ----------GDDGLPAPMEAEAYEDDVLAPGG----RAPAGDLLPSAFRVPAAFPTKVP 641
G GLP P + + P G R P G + PS P +
Sbjct: 1127 RGLKGHRGFTGLQGLPGP-PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG 1185
Query: 642 VPGP--GSGGNGPEREGPEEPG 661
PGP SG GP P PG
Sbjct: 1186 PPGPRGRSGETGPAGP-PGNPG 1206
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 52.4 bits (124), Expect = 3e-06
Identities = 144/566 (25%), Positives = 179/566 (31%), Gaps = 128/566 (22%)
Query: 493 AGPRFPELGPDGHQRLDYVPSSASREVRHG-------SDPAFAPGPRGLEPSGAPRPNLT 545
AG R P GP G + P + G A APG +G SG+P N
Sbjct: 194 AGERGPP-GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG--ESGSPGEN-- 248
Query: 546 QRFPCQAAARPGPDPAPEAEPERRG--GPEGRAGLRRWRLASYLSGCHGEDG--GDDGLP 601
PGP P P RG GP G AG R G DG G G P
Sbjct: 249 --------GSPGP-MGPRGLPGERGRTGPAGAAGAR------------GNDGQPGPAGPP 287
Query: 602 APMEAEAYEDDVLAPGGRA---PAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREG-- 656
P+ APG + P G P + P P PGP P +G
Sbjct: 288 GPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIP 347
Query: 657 -----PEEPGLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHK 711
PG+A F P +GA G
Sbjct: 348 GAKGSAGAPGIAGAPGFPGPRGP----------------PGPQGATG------------- 378
Query: 712 EQTVSETLGPGGEAVRSAASTKVAELLEKYKGPARDPG--GGAGAITVASHSKAVVSQAW 769
LGP G+ + E +GP +PG G GA A +
Sbjct: 379 ------PLGPKGQTGEPGIAGFKGE-----QGPKGEPGPAGPQGAPGPAG------EEGK 421
Query: 770 REEVAAPGAVG-----GERRSLESCLLDLRDSFAQQLHQEAERQP-GAASLTAAQLLDTL 823
R PG VG GER + + +D A ER P G A A
Sbjct: 422 RGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN--GDP 479
Query: 824 GRSGSDRLP-SRFLSAQSHSTSPQGLDSP--LPLEGSGAHQVLHNESKGSP-TSAYPERK 879
GR G LP +R L+ + PQG P P E ++G P +P K
Sbjct: 480 GRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK 539
Query: 880 G-SPTPGFSTRRGSP----TTGFIEQKGSPTSAYPERRGSPVPPVPERRSSPVPPVPERR 934
G + PG + +G P G + G +A P P P ER P +
Sbjct: 540 GANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP---GPAGPAGERGEQGAPGPSGFQ 596
Query: 935 GSLTLTISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENG 994
G P P E G G V G L+ P+GER E G P Q
Sbjct: 597 GL-------PGPPGPPGEGGKPGDQGV--PGEAGAPGLVGPRGERGFPGERGSPGAQ--- 644
Query: 995 QPESPRRLSLGQG-DSTEAATEERGP 1019
+ PR L G D + A+ GP
Sbjct: 645 GLQGPRGLPGTPGTDGPKGASGPAGP 670
Score = 48.9 bits (115), Expect = 3e-05
Identities = 167/678 (24%), Positives = 212/678 (31%), Gaps = 144/678 (21%)
Query: 466 PARPQGLFEKLRGGRAGFADPDDFTLGAGPRFP--ELGPDGHQRLDYVPSSASREVRHGS 523
P P G E+ G GF D AGP+ E GP G P A+ +
Sbjct: 433 PIGPPG--ERGAPGNRGFPGQDGL---AGPKGAPGERGPSGLAG----PKGANGDPGRPG 483
Query: 524 DPAFAPGPRGLE-------------PSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRG 570
+P PG RGL PSGAP + P AR P P+
Sbjct: 484 EPGL-PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542
Query: 571 GPEGRAGLRRWRLASYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAF 630
G G+AG + A L G G+D G+ G P PG PAG+
Sbjct: 543 GEPGKAGEKGLPGAPGLRGLPGKD-GETGAAGP------------PGPAGPAGERGEQGA 589
Query: 631 RVPAAFPTKVPVPG-PGSGGNGPEREGPEE---PGLAKQDSFR----SRLNPLVQRSSRL 682
P+ F PG PG GG ++ P E PGL R R +P Q
Sbjct: 590 PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 649
Query: 683 RSSLIFSTSQAEGAAGA--------AAATEKVQLLHKEQTVSETLGPGGEAVRSAASTKV 734
R + T +G GA A +Q + E+ + GP G+ V
Sbjct: 650 RG--LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD------RGDV 701
Query: 735 AELLEKYKGPARDPG--GGAGAITVASHSKAVVSQAWREEVAAPGAVGGERRSLESCLLD 792
E KGP PG GG G + + EV PG G
Sbjct: 702 GE-----KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS----------- 745
Query: 793 LRDSFAQQLHQEAER----QPGAASLTAAQLLDTLGRSGSDRLPSRFLSAQSHSTSPQGL 848
A ER PG A G G+D P Q +
Sbjct: 746 -----AGARGAPGERGETGPPGPAGFA--------GPPGADGQPGA-KGEQGEAGQKGDA 791
Query: 849 DSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAY 908
+P P SGA PT + G G P G + G P S
Sbjct: 792 GAPGPQGPSGA------PGPQGPTGVTGPKGARGAQGPPGATGFP--GAAGRVGPPGS-- 841
Query: 909 PERRGSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPA----------------E 952
G+P PP P S P R S +GE GPA
Sbjct: 842 ---NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA 898
Query: 953 EGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFP-VPQENGQPESPRRLSLGQGD--- 1008
EGP GP +G R ++ G+R E GFP +P +G+P + GD
Sbjct: 899 EGPPGP-----QGLAGQRGIVGLPGQR---GERGFPGLPGPSGEP-GKQGAPGASGDRGP 949
Query: 1009 ----STEAATEERGPRARLSSATANALYSSNLRDDTKAILEQISAHGQKHRAVPAPSPGP 1064
T G R S A+ + K + A G P SPGP
Sbjct: 950 PGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP 1009
Query: 1065 THNSPELGRPPAAGVLAP 1082
+ + G AG P
Sbjct: 1010 AGPTGKQGDRGEAGAQGP 1027
Score = 34.7 bits (78), Expect = 0.55
Identities = 54/202 (26%), Positives = 68/202 (33%), Gaps = 41/202 (20%)
Query: 493 AGPRFPELGPDGHQRLDYVPSSASREVRHGSDPAFAPGPRGLEPSGAPRPNLTQRFPCQA 552
+G R P GP G L RE G+D GP G + + + + + A
Sbjct: 944 SGDRGPP-GPVGPPGLTGPAGEPGREGSPGAD-----GPPGRDGAAGVKGDRGETGAVGA 997
Query: 553 AARPGP--DPAPEAEPERRG-----------GPEGRAGLRRWRLASYLSGCHGEDG---- 595
PGP P P ++G GP G AG R + G GE G
Sbjct: 998 PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1057
Query: 596 ----------GDDGLPAPMEAEAYEDDVLAPGG----RAPAGDLLPSAFRVPAAFPTKVP 641
G GLP P + + P G R P G + PS P +
Sbjct: 1058 RGLKGHRGFTGLQGLPGP-PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG 1116
Query: 642 VPGP--GSGGNGPEREGPEEPG 661
PGP SG GP P PG
Sbjct: 1117 PPGPRGRSGETGPAGP-PGNPG 1137
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 51.2 bits (121), Expect = 6e-06
Identities = 61/187 (32%), Positives = 71/187 (37%), Gaps = 25/187 (13%)
Query: 494 GPR-FPELGPDGHQRLDYVPSSASREVRHGS----DPAFAPGPRGLEPSGAPRPNLTQRF 548
GPR FP GP G L +P + G P PGPRG PSGAP + Q
Sbjct: 1216 GPRGFP--GPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRG--PSGAPGADGPQG- 1270
Query: 549 PCQAAARPGP-----DPAPEAEP--ERRGGPEGRAGLRRWRLASYLSGCHGEDG-----G 596
P PG +P EP GGP G G R + S SG G G G
Sbjct: 1271 PPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPG 1330
Query: 597 DDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGS--GGNGPE- 653
DDG + D PG PAG P + P + PGP G +GP
Sbjct: 1331 DDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPG 1390
Query: 654 REGPEEP 660
+ GP P
Sbjct: 1391 KRGPPGP 1397
Score = 44.7 bits (104), Expect = 5e-04
Identities = 55/196 (28%), Positives = 70/196 (35%), Gaps = 25/196 (12%)
Query: 479 GRAGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDPAFAPGPRGLEPSG 538
G G P T GP+ P GP G L P G PGP G+
Sbjct: 946 GERGPNGPQGPTGFPGPKGPP-GPPGKDGLPGHPGQRGETGFQGKTGP--PGPPGVV--- 999
Query: 539 APRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDG--- 595
P+ + P PGP P P E G G AG + +G G+DG
Sbjct: 1000 GPQGPTGETGPMGERGHPGP-PGPPGEQ----GLPGLAGKEGTKGDPGPAGLPGKDGPPG 1054
Query: 596 -----GDDGLPAPMEAEAYEDDVLAPGGRAPA---GDLLPSAFRVPAAFPTK---VPVPG 644
GD GLP P+ A + + PG PA G+ P+ P P + PG
Sbjct: 1055 LRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPG 1114
Query: 645 PGSGGNGPEREGPEEP 660
P P +GP+ P
Sbjct: 1115 PAGEKGAPGEKGPQGP 1130
Score = 40.8 bits (94), Expect = 0.008
Identities = 64/211 (30%), Positives = 81/211 (38%), Gaps = 38/211 (18%)
Query: 466 PARPQG-LFEKLRGGRAGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSD 524
P P+G EK G +G A P GP+ P G DG P + V D
Sbjct: 1301 PPGPKGERGEKGESGPSGAAGPP------GPKGPP-GDDG-------PKGSPGPVGFPGD 1346
Query: 525 PA--FAPGPRGLEPSGAPRPNLTQRFPCQAAARPGP--DPAPEAEPERRG-----GPEGR 575
P PGP G + G P P Q + PGP +P P P +RG GPEGR
Sbjct: 1347 PGPPGEPGPAGQD--GPPGDKGDDGEPGQTGS-PGPTGEPGPSGPPGKRGPPGPAGPEGR 1403
Query: 576 AGLRRWRLASYLSGCHGEDG--GDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVP 633
G + + + L G G+ G G G P + G P G+ P
Sbjct: 1404 QGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR------GIPGPVGEQGLPGSPGP 1457
Query: 634 AAFPTKVPVPG-PG-SGGNGPEREGPEEPGL 662
P + PG PG G +GP+ E PGL
Sbjct: 1458 DGPPGPMGPPGLPGLKGDSGPKGE-KGHPGL 1487
Score = 40.4 bits (93), Expect = 0.010
Identities = 120/479 (25%), Positives = 146/479 (30%), Gaps = 144/479 (30%)
Query: 529 PGPRGLEPSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRG--------GPEGRAGLRR 580
PGP G SG + P GP P P +P RRG G G+ G +
Sbjct: 570 PGPVGPPGSGGLKGEPGDVGPQGPRGVQGP-PGPAGKPGRRGRAGSDGARGMPGQTGPKG 628
Query: 581 WRLASYLSGCHGEDG-----GDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAA 635
R L+G GE G G G P P + D G R G+ P P
Sbjct: 629 DRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKG 688
Query: 636 FPTKVPVPG-------PGSGGNGPEREGPE-EPGLAKQDSFRSRLNPLVQRSSRLRSSLI 687
P PG PG GN GP+ EPG Q NP
Sbjct: 689 PPGPPGPPGVTGMDGQPGPKGN----VGPQGEPGPPGQQG-----NP------------- 726
Query: 688 FSTSQAEGAAGAAAATEKVQLLHKEQTVSETLGPGGEAVRSAASTKVAELLEKYKGPARD 747
A+G G A +GP GE KGP
Sbjct: 727 ----GAQGLPGPQGA----------------IGPPGE-----------------KGPLGK 749
Query: 748 PG--GGAGAITVASHSKAVVSQAWREEVAAPGAVGGERRSLESCLLDLRDSFAQQLHQEA 805
PG G GA H + PG GG+ Q
Sbjct: 750 PGLPGMPGADGPPGHPG---------KEGPPGEKGGQ---------------GPPGPQGP 785
Query: 806 ERQPGAASLTAAQ----LLDTLGRSGSDRLPS-------RFLSAQSHSTSPQGLDSPLPL 854
PG + A L T G G D P + + P+G D P
Sbjct: 786 IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGP 845
Query: 855 EGSGAHQVLHNESKGSPTSAYPE----RKGSP-TPGFSTRRGSPTTGFIEQKGSPTSAYP 909
+G G G P P + G P PG+ R+G G I G P A
Sbjct: 846 KGRGG-------PNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPK--GSIGFPGFP-GANG 895
Query: 910 ER--RGSPVPPVPERRSSPVPPVPERRGSLTLT--------ISGESPKAGPAEEGPSGP 958
E+ RG+P P P + P P ER G +T G+ P P E GP+GP
Sbjct: 896 EKGGRGTPGKPGPRGQRGPTGPRGER-GPRGITGKPGPKGNSGGDGPAGPPGERGPNGP 953
Score = 38.5 bits (88), Expect = 0.038
Identities = 124/563 (22%), Positives = 165/563 (29%), Gaps = 122/563 (21%)
Query: 501 GPDGHQRLDYVPSSASREVRHGSD-PAFAPG---PRGLE--PSGAPRPNLTQRFPCQAAA 554
GP G Q L P A +E G PA PG P GL P P +
Sbjct: 1021 GPPGEQGL---PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNE 1077
Query: 555 RPGPDPAPEAEPERRG--GPEGRAGLRRWRLASYLSGCHGEDG--GDDGLPAPMEAEAYE 610
P P P P RG G G G+ G GE G G+ G P + +
Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137
Query: 611 DDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGPEEP-GLAKQDSFR 669
V PG P G + P + G P GP+ P G
Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGAD 1197
Query: 670 SRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLL-------HKEQT--VSETLG 720
P Q+ +F EG G V L K +T V +
Sbjct: 1198 GEPGPRGQQG-------LFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGP 1250
Query: 721 PGGEAVRSAASTKVAELLEKYKGPARDPGGGAGAITVASHSKAVVSQAWREEVAAPGAVG 780
PG R + A+ GP PGG + PGAVG
Sbjct: 1251 PGPPGPRGPSGAPGAD------GPQGPPGG----------------------IGNPGAVG 1282
Query: 781 GERRSLESCLLDLRDSFAQQLHQEAERQPGAASLTAAQLLDTLGRSGSDRLPSRFLSAQS 840
+ E+ L + + G + + A G G P
Sbjct: 1283 EKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAA-----GPPGPKGPPG------- 1330
Query: 841 HSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSP-TTGFIE 899
P+G P+ G G P P + P PG G P TG
Sbjct: 1331 -DDGPKGSPGPVGFPGD----------PGPPGEPGPAGQDGP-PGDKGDDGEPGQTGSPG 1378
Query: 900 QKGSP-TSAYPERRGSPVPPVPERRS-------------------------SPVPPVPER 933
G P S P +RG P P PE R +P P P+
Sbjct: 1379 PTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDG 1438
Query: 934 RGSLTLTISGESPKAGPAEEGPSGPMEVL-------------RKGSLRLRQLLSPKGERR 980
+ + + P +GP GPM KG L L+ P GE+
Sbjct: 1439 LRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQG 1498
Query: 981 MEDEGGFPVPQENGQPESPRRLS 1003
+ + G P PQ + P+ + ++
Sbjct: 1499 EKGDRGLPGPQGSSGPKGEQGIT 1521
Score = 36.2 bits (82), Expect = 0.19
Identities = 56/229 (24%), Positives = 79/229 (34%), Gaps = 40/229 (17%)
Query: 467 ARPQGLFEKLRGGRAGFADPDDFTLGAGPRFP-----------ELGPDGHQRLDYVPSSA 515
++ Q + ++ R G A P T GP P ++GP G + + P A
Sbjct: 544 SQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPA 603
Query: 516 SREVRHGSDPAFAPGPRGLEPSGAPRPNL----TQRFPCQAAAR--PGPD--PAPEAEPE 567
+ R G A + G RG+ P+ + P + R PGP P P +
Sbjct: 604 GKPGRRGR--AGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDG 661
Query: 568 RRG-----GPEGRAGLRRWRLASYLSGCHGEDG-----GDDGLPAPMEAEAYEDDVLAPG 617
RG GP G G R G G G G DG P P + + PG
Sbjct: 662 ERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPG 721
Query: 618 GRA---------PAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGP 657
+ P G + P + P P +PG P +EGP
Sbjct: 722 QQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGP 770
Score = 35.4 bits (80), Expect = 0.32
Identities = 49/188 (26%), Positives = 68/188 (36%), Gaps = 20/188 (10%)
Query: 487 DDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDPAFAPGPRGLEPSGAPRP---- 542
DD T G G P+ D + S+A + + S+PA PG + G
Sbjct: 353 DDLTYGEGEENPDQPTDPGAGAEIPTSTA--DTSNSSNPAPPPGEGADDLEGEFTEETIR 410
Query: 543 NLTQRF------PCQAAARPGPDPAPEAEP--ERRGGPEGRAGLRRWRL----ASYLSGC 590
NL + + P + + GP + E GGP G G + + G
Sbjct: 411 NLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGP 470
Query: 591 HGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAG-DLLPSAFRVPAAFPTKVPVPGPGSGG 649
G +G GLP P V PG R P G LP A +P T + +P GG
Sbjct: 471 PGPEG-PAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGG 529
Query: 650 NGPEREGP 657
+GP
Sbjct: 530 GDAGSKGP 537
Score = 33.5 bits (75), Expect = 1.2
Identities = 49/188 (26%), Positives = 63/188 (33%), Gaps = 37/188 (19%)
Query: 499 ELGPDGHQRLDYVPSSASREVRHGSD-PAFAPGPRG-LEPSGAPRPNLTQR--------- 547
E+GP G + D R +G P PG +G L G P Q
Sbjct: 830 EIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPG 889
Query: 548 FPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDGGDDGLPAPMEAE 607
FP + G + P + GP G G R R + G G GG DG P
Sbjct: 890 FPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGG-DGPAGP---- 944
Query: 608 AYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREG-PEEPGLAKQD 666
PG R P G P+ F PGP P ++G P PG +
Sbjct: 945 --------PGERGPNGPQGPTGF------------PGPKGPPGPPGKDGLPGHPGQRGET 984
Query: 667 SFRSRLNP 674
F+ + P
Sbjct: 985 GFQGKTGP 992
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 50.1 bits (118), Expect = 1e-05
Identities = 165/688 (23%), Positives = 228/688 (33%), Gaps = 162/688 (23%)
Query: 525 PAFAPGPRGLEP-SGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRL 583
PA AP P L+P GA P R P A P P P A+P P L
Sbjct: 754 PASAP-PEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGL 812
Query: 584 ASYLSGCHGEDGGDDGLPA----------PMEAEAYEDDVLAPGGRAPAGDLLPSAFRVP 633
+S G GD G P A E+ V P RAP P A R P
Sbjct: 813 SS-----PGPKPGDSGYETETPFSPEGAFPGGGAAEEEGV--PRPRAPPEPPDPGAPR-P 864
Query: 634 AAFPTKVPVPGPGSGGNGPEREGPEEPGLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQA 693
P +P+PGP E+P Q S L L + +R +T++
Sbjct: 865 PPDPGPLPLPGP-----------REKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARE 913
Query: 694 EG---AAGAAAATEKVQLLHKEQTVSETLGPGGEAVRSAASTKVAELLEKYKGPARDPGG 750
G A EKV L+++ TV LG G +A + +LE G R P
Sbjct: 914 TGPRKAGRGPGNREKVPGLNRDPTV---LGNGKQAPSLSLPVNGVTVLE--NGDQRAP-- 966
Query: 751 GAGAITVASHSKAVVSQAWREEVAAPGAVGGERRSLESCLLDLRDSFAQQLHQEAERQPG 810
G A+ + A+ S E+V G + RR ++ ++ + + E+
Sbjct: 967 --GIEEKAAENGALGSPEREEKVLENGELTPPRREEKAL-----ENGELRSPEAGEKVLV 1019
Query: 811 AASLTAAQLLDTLGRSGSDRLPSRFLSAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKG- 869
LT + D + +G R P + + T P +P P E + ES G
Sbjct: 1020 NGGLTPPKSEDKVSENGGLRFPRN--TERPPETGP--WRAPGPWEKT-------PESWGP 1068
Query: 870 SPTSAYP------ERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPVPERR 923
+PT P ER +P+ S+R G T +P P + + P ERR
Sbjct: 1069 APTIGEPAPETSLERAPAPSAVVSSRNGGET--------APGPLGPAPKNGTLEPGTERR 1120
Query: 924 SSPVPPVPERRGSLTLTI-------------------SGESPKAG------------PAE 952
+ P G+ L + SG KAG P
Sbjct: 1121 APETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLP 1180
Query: 953 EGPSGPMEVLRKGSLRLRQLLSPKGERRMEDE--GGFPVPQENGQPESPRRLSLGQGDST 1010
P L R R ++P+GE D GG +G P P R +G
Sbjct: 1181 PPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPER----KGPEM 1236
Query: 1011 EAATEERGPRARLSSATANALYSSNLRDDTKAILEQISAHGQKHRAVPAPSPGPTHNSPE 1070
+ GP S + KA L ++S P P PGP
Sbjct: 1237 PRLFLDLGPPQGNS-------------EQIKARLSRLSLALPPLTLTPFPGPGPR----- 1278
Query: 1071 LGRPPAAGVLAPDMSDKDKCSAIFRSDSLGTQGRLSRTLPASAEERDRLLRRMESMRKEK 1130
RPP G D +A + G G PA + D E +E
Sbjct: 1279 --RPPWEGA--------DAGAAGGEAGGAGAPG------PAEEDGED------EDEDEE- 1315
Query: 1131 RVYSRFEVFCKKEEASSPGAGEGPAEEG 1158
+ EEA++PGA GP G
Sbjct: 1316 ----------EDEEAAAPGAAAGPRGPG 1333
Score = 35.4 bits (80), Expect = 0.32
Identities = 141/605 (23%), Positives = 193/605 (31%), Gaps = 104/605 (17%)
Query: 481 AGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDPAFA-PGPRGLEPSGA 539
A DP G GP P + E P A PG E G
Sbjct: 796 AASPDPPSAVASPGSGLSSPGPK--------PGDSGYETETPFSPEGAFPGGGAAEEEGV 847
Query: 540 PRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYL-----SGCHGED 594
PRP P A RP PDP P P R P + +L L GE
Sbjct: 848 PRPRAPPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEK 907
Query: 595 GGDDGLPAPMEAEAYEDDVLAPGGRAPAG-DLLPSAFRVPAAFPTKVPVPG---PGSGGN 650
G P +A GR P + +P R P P P +G
Sbjct: 908 GATARETGPRKA-----------GRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGVT 956
Query: 651 GPEREGPEEPGLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAE-----GAAGAAAATEK 705
E PG+ ++ + L + L + + + E G + A EK
Sbjct: 957 VLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEK 1016
Query: 706 VQL------LHKEQTVSETLGPGGEAVRSAASTKVAELLEKYKGPA---RDPGGGAGAIT 756
V + E VSE G +R +T+ ++ P + P A T
Sbjct: 1017 VLVNGGLTPPKSEDKVSENGG-----LRFPRNTERPPETGPWRAPGPWEKTPESWGPAPT 1071
Query: 757 VASHSKAVVSQAWREEVAAPGAVGGERRSLESCLLDL-----RDSFAQQLHQEAERQPGA 811
+ + + E AP AV R E+ L + + A GA
Sbjct: 1072 IGEPA----PETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGA 1127
Query: 812 ASLTAAQLLDTLGRSGSDRL---------PSRFLSAQS---HSTSPQGLDSPLPLEGSGA 859
A LD LG G + P + A++ +T PQ PLP
Sbjct: 1128 PRAPGAGRLD-LGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQ 1186
Query: 860 HQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPV 919
+ L + +P A PE PG R T + G P PER+G +P +
Sbjct: 1187 PRRL----EPAPPRARPEVAPEGEPGAPDSRAGGDTA-LSGDGDPPK--PERKGPEMPRL 1239
Query: 920 -----PERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLS 974
P + +S R SL L +P GP P P E G +
Sbjct: 1240 FLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRP--PWEGADAG--------A 1289
Query: 975 PKGERRMEDEGGFPVP-QENGQPESPRRLSLGQGDSTEAATEERGP-RAR-------LSS 1025
GE G P P +E+G+ E + + AA RGP RAR +SS
Sbjct: 1290 AGGE---AGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSS 1346
Query: 1026 ATANA 1030
A A+A
Sbjct: 1347 ADADA 1351
>gi|145199237 transcription elongation factor B polypeptide 3 binding
protein 1 [Homo sapiens]
Length = 1221
Score = 49.7 bits (117), Expect = 2e-05
Identities = 77/343 (22%), Positives = 124/343 (36%), Gaps = 38/343 (11%)
Query: 851 PLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFST--------------RRGSPTTG 896
P P + + QV ++ G P P++K + P + RG P
Sbjct: 351 PPPAKPASPAQVQSSQDGGCPKEGKPKKKKTGAPPAPSCKDGAQGKDKTKDKGRGRPVEK 410
Query: 897 FIEQKGSPTSAYPERRGSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGP----AE 952
K P ++ P R+ ++ SS P +G SP +G A
Sbjct: 411 PRADKKGPQASSPRRKAERPEGTKKKPSSATPVATSGKGRPDRPARRPSPTSGDSRPAAG 470
Query: 953 EGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESPRRLSLGQGDSTEA 1012
GP P+++ + S + + + R DEG ++ R LS E+
Sbjct: 471 RGPPRPLQLPDRKSTKAPSGKLVERKARSLDEGA----SQDAPKLKKRALSHADLFGDES 526
Query: 1013 ATEERGPRARLSSATANALYSSNLRDDTKAILEQISAHGQKHR--AVPAPSPGPTHNSPE 1070
E GP +A SS+ D+ + L A G R A P PSP P+ +S
Sbjct: 527 EDEAAGPGVPSVWPSALPSLSSDSDSDSDSSLGFPEAQGPPKRLKASPPPSPAPSSSSSS 586
Query: 1071 LGRPPAAGV----------LAPDMSDKDKCSAIF-RSDSLGTQ--GRLSRTLPASAEERD 1117
+AG + D ++C IF S S+ T+ GRL+R P + +
Sbjct: 587 SSSTSSAGADVDYSALEKEVDFDSDPMEECLRIFNESTSVKTEDRGRLARQPPKEEKSEE 646
Query: 1118 RLLRRMESM-RKEKRVYSRFEVFCKKEEASSPGAGEGPAEEGT 1159
+ L + ++ +KR S ++ E G PA T
Sbjct: 647 KGLSGLTTLFPGQKRRISHLSKQGQEVEPPRRGPAVPPARPPT 689
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 48.9 bits (115), Expect = 3e-05
Identities = 178/716 (24%), Positives = 223/716 (31%), Gaps = 166/716 (23%)
Query: 466 PARPQGL-FEKLRGGRAGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSD 524
PA P G+ EK G G P AGPR G G D VP GS
Sbjct: 493 PAGPNGIPGEKGPAGERGAPGP------AGPR----GAAGEPGRDGVPGGPGMRGMPGS- 541
Query: 525 PAFAPGPRGLEPSGAPRPNLTQRFPCQAAARPGPD--PAPEAEPERRG--GPEGRAGLRR 580
P G G P P +Q + RPGP P +P G GP+G G
Sbjct: 542 ------PGGPGSDGKPGPPGSQG----ESGRPGPPGPSGPRGQPGVMGFPGPKGNDGA-- 589
Query: 581 WRLASYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKV 640
G +GE GG G P P + G + P G P + P
Sbjct: 590 -------PGKNGERGGPGG-PGPQGPPGKNGET---GPQGPPGPTGPGGDKGDTGPPGPQ 638
Query: 641 PVPG-PGSGGNGPEREGPEEPGLAKQDSFR--------------SRLNPLVQRSSRLRSS 685
+ G PG+GG E P EPG K D+ R P + + LR
Sbjct: 639 GLQGLPGTGGPPGENGKPGEPG-PKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG 697
Query: 686 L-IFSTSQAEGAAG-----AAAATEKVQLLHKEQ----------TVSETLGPGGEAVRSA 729
+GAAG AA T +Q + E+ E GPG + V
Sbjct: 698 AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757
Query: 730 ASTKVAELLEKYKGPARDPG--GGAGAITVASHSKAVVSQAWREEVAAPGAVGGERRSLE 787
+ GPA PG G GA + + S R E PG G
Sbjct: 758 DGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAG------- 810
Query: 788 SCLLDLRDSFAQQLHQEAERQPGAASLTAAQLLDTLGRSGSDRLPSRFLSAQSHSTSPQG 847
F Q E PG A G G P ++ + P G
Sbjct: 811 ---------FPGAPGQNGE--PGGKGERGAP-----GEKGEGGPPG--VAGPPGGSGPAG 852
Query: 848 LDSPLPLEGSGAHQVLHNESKGSPTSA-YPERKGSP-------TPGFSTRRGSP------ 893
P ++G S G P +A +P +G P PG GSP
Sbjct: 853 PPGPQGVKG-------ERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP 905
Query: 894 -TTGFIEQKGSP-------TSAYPERRGSPVPPVPERRSSPV--------------PPVP 931
G GSP + P +GSP P P+ P +P
Sbjct: 906 GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMP 965
Query: 932 ERRGSL-TLTISGESPKAG----PAEEGPSGPM----------EVLRKGSLRLRQLL--- 973
RGS + GES K G E GP GP E R G+ L
Sbjct: 966 GPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRD 1025
Query: 974 -SPKGERRMEDEGGFPVPQENGQPESPRRLSLGQGDSTEAATEERGPRARLSSA-TANAL 1031
SP G+ + G P G P P + + GP A + A
Sbjct: 1026 GSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAP 1085
Query: 1032 YSSNLRDDTKAILEQISAHGQKHRAVP----AP-SPGPTHNSPELGRPPAAGVLAP 1082
R D E+ +A + HR P AP SPGP +G P AG P
Sbjct: 1086 GPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP 1141
Score = 40.0 bits (92), Expect = 0.013
Identities = 57/202 (28%), Positives = 67/202 (33%), Gaps = 22/202 (10%)
Query: 466 PARPQGLFEKLRGGRAGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDP 525
P PQGL G AG T G R G DG D P +GS
Sbjct: 994 PPGPQGL-----PGLAG-------TAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPG 1041
Query: 526 AFA----PGPRGLEPSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRW 581
A PGP G + + P A PGP + A + GP G G
Sbjct: 1042 APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQ--GPRGDKGETGE 1099
Query: 582 RLASYLSGCHGEDG--GDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTK 639
R A+ + G G G G G P P + G R P G P + P
Sbjct: 1100 RGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPG- 1158
Query: 640 VPVPGPGSGGNGPEREGPEEPG 661
P+ PG GN ER PG
Sbjct: 1159 -PIGPPGPRGNRGERGSEGSPG 1179
Score = 39.7 bits (91), Expect = 0.017
Identities = 56/196 (28%), Positives = 65/196 (33%), Gaps = 29/196 (14%)
Query: 476 LRGGRAGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDPAFAPGPRGLE 535
LRGG AG + GPR G G + VP + + + GS PG GL
Sbjct: 427 LRGG-AGEPGKNGAKGEPGPR----GERGEAGIPGVPGAKGEDGKDGSPGE--PGANGLP 479
Query: 536 PSGAPRPNLTQRFPCQAAARPGPD-PAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGED 594
+ R R P PG PA E GP G AG G G
Sbjct: 480 GAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMP 539
Query: 595 G-----GDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGG 649
G G DG P P PG + +G P P P + PGP
Sbjct: 540 GSPGGPGSDGKPGP------------PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND 587
Query: 650 NGP----EREGPEEPG 661
P ER GP PG
Sbjct: 588 GAPGKNGERGGPGGPG 603
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 48.9 bits (115), Expect = 3e-05
Identities = 121/518 (23%), Positives = 163/518 (31%), Gaps = 75/518 (14%)
Query: 530 GPRGLEPSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSG 589
GP P AP ++T P +A A P P P A P +G P A
Sbjct: 899 GPATPAPKQAPALSMTSSSPKKARATPAPKGIP-ASPSPKGAPTPPAATPP--------- 948
Query: 590 CHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPA---GDLLPSAFRVPAAFPTKVPVPGPG 646
G P+P A P P+ G PS P P P P
Sbjct: 949 ---SPKGGPATPSPKWAPT------PPAATPPSPKGGPATPSPKGAPT--PPAATPPSPK 997
Query: 647 SGGNGPEREGPEEPGLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKV 706
G P +G P S + +P + S+ +T + + AA K
Sbjct: 998 GGPATPSPKGAPTPPAVTPPSPKG--SPAATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055
Query: 707 QLLHKEQTV-SETLGPGGEAVRSAASTKVAELLEKYKGPARDPGGGAGAITVASHSKAVV 765
T+ S GP +++ A + A GPA GA A+
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115
Query: 766 SQAWREEVAAPGAVGGERRSLESCLLDLRDSFAQQLHQEAERQPGAASLTAAQLLDTLGR 825
A AP S + L A + A P A + L T
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGL-------ATPPPKGAPTTPAATPPSPKGGLATPPP 1168
Query: 826 SGSDRLPSRFLSAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPG 885
G+ P A + + GL +P P KG A P KG+PT
Sbjct: 1169 KGAPTTP-----AATPPSPKGGLATPSPKGAPTTPAATPPSPKGG--LATPSPKGAPTTP 1221
Query: 886 FSTRRGSPTTGFI--EQKGSPTSAY---PERRGSPVPPVPERRSSPVPPV---PERRGSL 937
+T SP G KG+PT+ P +G P P P + +P PP P +G L
Sbjct: 1222 AATPP-SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP--KGAPTPPAATPPSLKGGL 1278
Query: 938 TL----------TISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGF 987
++ SPK GPA P G + SPKG G
Sbjct: 1279 ATPPHKGAPNPAVVTPPSPKGGPATSPPKG------APTPPAATPPSPKGSPGTPPPKGA 1332
Query: 988 PV------PQENGQPESPRRLSLGQGDSTEAATEERGP 1019
P P G P P +G T +++E GP
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE-GP 1369
Score = 46.2 bits (108), Expect = 2e-04
Identities = 45/147 (30%), Positives = 62/147 (42%), Gaps = 23/147 (15%)
Query: 868 KGSPTSAY---PERKGSPTPGFST--RRGSPTTGFIEQKGSPTSAYPERRGSP--VPPVP 920
KG+PT P KG+PT +T +G PTT ++ +P +A P +G P PP P
Sbjct: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP 1389
Query: 921 ERRSSPVPPVPERRGSLTL-TISGESPKAGPA----EEGPSGPMEVLRKGSL---RLRQL 972
+R P +P +G T + SPK PA EG + P KG L + +
Sbjct: 1390 KRG----PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP----SKGDLTPPAVTPV 1441
Query: 973 LSPKGERRMEDEGGFPVPQENGQPESP 999
K +GG P G P P
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLP 1468
Score = 43.9 bits (102), Expect = 0.001
Identities = 147/677 (21%), Positives = 211/677 (31%), Gaps = 119/677 (17%)
Query: 462 PQLTPARPQGLFEKLRGGRAGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRH 521
P TP P+G G A P P P P + PS
Sbjct: 1152 PAATPPSPKG----------GLATPPP---KGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
Query: 522 GSDPAFAPGPRG----LEPSGAPR-PNLTQRFPCQAAARPGPDPAPEAE----PERRGGP 572
+ P P P+G P GAP P T P A P P AP P +GGP
Sbjct: 1199 AATP---PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255
Query: 573 EGR----AGLRRWRLASYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPS 628
A L G GL P A V+ P +P G S
Sbjct: 1256 ATPPPKGAPTPPAATPPSLKG---------GLATPPHKGAPNPAVVTPP--SPKGGPATS 1304
Query: 629 AFRVPAAFPTKVPVPGPGSGGNGPEREGPEEPGLAKQDSFRSRLNPLVQRSSRLRSSLIF 688
+ P P GS G P + P P + + P SS+ +
Sbjct: 1305 PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT--- 1361
Query: 689 STSQAEGAAGAAAATEKVQLLHKEQTVSETLGPGGEAVRSAASTKVAELLEKYKGPARDP 748
+ S EG AA HK GG A+ + S K + KG P
Sbjct: 1362 TPSSKEGPTPPAATPS-----HK----------GGPAM-TPPSPKRGPAIPSPKGDPTSP 1405
Query: 749 GGGAGAITVASHSKAVVSQAWREEVAAPGAVGGERRSLESCLLDLRDSFAQQLHQEAERQ 808
A+ S KA + RE A P G+ + L+ + A +
Sbjct: 1406 -----AVIPLSPKKAPATPVTREGAATPSK--GDLTPPAVTPVSLKKAPATSAPKGGPAT 1458
Query: 809 P---GAASLTAAQLLDTLGRSGSDRLPSRFLSAQSHSTSPQGLDSPLPLEGSGAHQVLHN 865
P G +L A T P + ++ S +P +P P+ V+ +
Sbjct: 1459 PSSKGDPTLPAV----TPPSPKEPPAPKQVATSSSPKKAPA---TPAPMGAPTLPAVIPS 1511
Query: 866 ESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPVPERRSS 925
K P A P + P +PT + +K T A E P VP + +
Sbjct: 1512 SPKEVP--ATPSSRRDPI--------APTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561
Query: 926 PVPPVPERRGSLTLTISGESPKA--GPAEEGPSGPMEVLRKGSLRL---RQLLSPKGERR 980
P P P+ + + SP A +G P E+L ++ ++ +P
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621
Query: 981 MEDEGGFPVPQENGQPESPRRLSLGQGDSTEAATEERGPRARLSSATANALYSSNLRDDT 1040
E G P G P SP + ++ T ++ + A +
Sbjct: 1622 PSPEKGPATPAPKGTPTSP---PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678
Query: 1041 KAILEQISAHGQKHRAVPAPS-----PGPTHNSPELGRPPAAG-VLAPDMSDKDKCSAIF 1094
A+ E + A PAP PT P+ + A + PD S K+
Sbjct: 1679 TALKEVLVA--------PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKN------ 1724
Query: 1095 RSDSLGTQGRLSRTLPA 1111
G++G LS PA
Sbjct: 1725 -----GSKGPLSTVAPA 1736
Score = 41.2 bits (95), Expect = 0.006
Identities = 57/218 (26%), Positives = 69/218 (31%), Gaps = 37/218 (16%)
Query: 831 LPSRFLSAQSHSTSPQGLDSPLPLEGSGA---HQVLHNESKG-------SPT-------- 872
LP LS Q SP SP P GA V KG +PT
Sbjct: 836 LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPF 895
Query: 873 ----SAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPV---PERRSS 925
A P K +P ++ KG P S P +G+P PP P +
Sbjct: 896 PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS--PSPKGAPTPPAATPPSPKGG 953
Query: 926 PVPPVPERRGSLTLTISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEG 985
P P P + + SPK GPA P G + SPKG
Sbjct: 954 PATPSP-KWAPTPPAATPPSPKGGPATPSPKG------APTPPAATPPSPKGGPATPSPK 1006
Query: 986 GFPVPQENGQPE---SPRRLSLGQGDSTEAATEERGPR 1020
G P P P SP +G ST A P+
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK 1044
Score = 35.0 bits (79), Expect = 0.42
Identities = 45/183 (24%), Positives = 62/183 (33%), Gaps = 30/183 (16%)
Query: 837 SAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSPTTG 896
+A S T DSP PL S + Q T P +KGS P S
Sbjct: 780 TASSKGTLTYLADSPSPLGVSVSPQ----------TKRPPTKKGSAGPDTPIGNLSSPVS 829
Query: 897 FIEQKGSPTSAY--------PERRGSPVPPVPERRSSPVPPVPERRGSLTL--------- 939
+E P ++ P SP PP P+ +P P +TL
Sbjct: 830 PVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPS 889
Query: 940 TISGESPKAGPAEEGP--SGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPE 997
++ PK GPA P + + + + R +PKG G P P P
Sbjct: 890 VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA-ATPP 948
Query: 998 SPR 1000
SP+
Sbjct: 949 SPK 951
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 47.8 bits (112), Expect = 6e-05
Identities = 75/279 (26%), Positives = 97/279 (34%), Gaps = 58/279 (20%)
Query: 839 QSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTR-RGSPTTGF 897
+SHS S G P EG + GS +Y + PG S R SP+
Sbjct: 715 RSHSLSRPG-----PTEGDAEGEA--EGPVGSTLGSYATL--TRRPGRSALVRTSPSVTP 765
Query: 898 IEQKGSPTS---AYPERRGSPVPPVPERRSSPVPPVPE-----------------RRGSL 937
+G+P S A RR P PP P+R SS P PE RR +L
Sbjct: 766 TPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTL 825
Query: 938 TLTISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGE-RRMEDEGGFPV---PQEN 993
+ P PA GP+ E G GE +EG + P+
Sbjct: 826 SEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPA 885
Query: 994 GQPESPRRLSLGQG---DSTEAATEERGPRARLSSATANALYSSNLRDDTKAILEQISAH 1050
G P PR + G + TE+ T +R P+ R AL + + T
Sbjct: 886 GPP--PRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPG-------- 935
Query: 1051 GQKHRAVPAPSPGPTHNSPELGRP-------PAAGVLAP 1082
A P PSP P + P P PA GV P
Sbjct: 936 ----PAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTP 970
Score = 33.9 bits (76), Expect = 0.94
Identities = 47/164 (28%), Positives = 65/164 (39%), Gaps = 30/164 (18%)
Query: 549 PCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDGGDDGLPAPM-EAE 607
P + ++ GP P P E G EG G RR R S +G G PAP A
Sbjct: 791 PKRLSSVSGPSPEPPPLDESPGPKEGATGPRR-RTLSEPAG----PSEPPGPPAPAGPAS 845
Query: 608 AYEDDVLAPGGRAP----AGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGPEEPG-- 661
E++ P G P +G+ LP A + GP P RE P PG
Sbjct: 846 DTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP------PPRETPVPPGLD 899
Query: 662 --LAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAAT 703
L + D+ + R P + L+++L+ A G A+AT
Sbjct: 900 FNLTESDTVKRR--PKCREREPLQTALL--------AFGVASAT 933
Score = 31.2 bits (69), Expect = 6.1
Identities = 119/550 (21%), Positives = 170/550 (30%), Gaps = 77/550 (14%)
Query: 464 LTPARP---QGLFEKLRGGRAGFADPDDFTLGAGPRFPELG--PDGHQRLDYVPSSASRE 518
L PAR + + + RG P G P P+ P+G +R P S
Sbjct: 608 LPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTER---PPKLCSSL 664
Query: 519 VRHGSDPAFAPGPRGLEPSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGL 578
G P P+G S AP P + A P P P+RR R G
Sbjct: 665 PGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPG- 723
Query: 579 RRWRLASYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPT 638
G+ G+ P +Y P GR+ PS PA
Sbjct: 724 ----------PTEGDAEGEAEGPVGSTLGSYATLTRRP-GRSALVRTSPSVTPTPAR--- 769
Query: 639 KVPVPGPGSGGNGPEREGPEEPGLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAG 698
P S R+GP P + S V S L S EGA G
Sbjct: 770 --GTPRSQSFALRARRKGPPPPPPKRLSS--------VSGPSPEPPPLDESPGPKEGATG 819
Query: 699 AAAATEKVQLLHKEQTVSETLGPGGEAVRSAASTKVAELLEKYKGPARDP---GGGAGAI 755
+ +T+SE GP A + ++ E+ GP P G +
Sbjct: 820 P-----------RRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGL 868
Query: 756 TVASHSKAVVSQAWREEVAAPGAVGGERRSLESCLLDLRDSFAQQLHQE---AERQPGAA 812
A + Q R + A P R + LD + + + + ER+P
Sbjct: 869 PFAEEGNLTIKQ--RPKPAGP----PPRETPVPPGLDFNLTESDTVKRRPKCREREPLQT 922
Query: 813 SLTAAQLLDTLGRSGSDRLPSRFLSAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPT 872
+L A G + + P+ L + + SP P P S Q + SP
Sbjct: 923 ALLA------FGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSP- 975
Query: 873 SAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPVPERRSSPVPPVPE 932
+ P P PG + S G E +P + + VP ++P PV
Sbjct: 976 AMQPPVPPCPGPGLESSAASRWNGETEPPAAPAA---------LLKVPGAGTAP-KPVSV 1025
Query: 933 RRGSLTLTISGESPKAGPAEEGPSGPMEVLRKG----SLRLRQLLSPKGERRMEDEGGFP 988
L + +P+ GP P P G RL Q S E
Sbjct: 1026 ACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIG 1085
Query: 989 VPQENGQPES 998
++ G P +
Sbjct: 1086 TKEQEGTPSA 1095
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 47.8 bits (112), Expect = 6e-05
Identities = 75/279 (26%), Positives = 97/279 (34%), Gaps = 58/279 (20%)
Query: 839 QSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTR-RGSPTTGF 897
+SHS S G P EG + GS +Y + PG S R SP+
Sbjct: 797 RSHSLSRPG-----PTEGDAEGEA--EGPVGSTLGSYATL--TRRPGRSALVRTSPSVTP 847
Query: 898 IEQKGSPTS---AYPERRGSPVPPVPERRSSPVPPVPE-----------------RRGSL 937
+G+P S A RR P PP P+R SS P PE RR +L
Sbjct: 848 TPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTL 907
Query: 938 TLTISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGE-RRMEDEGGFPV---PQEN 993
+ P PA GP+ E G GE +EG + P+
Sbjct: 908 SEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPA 967
Query: 994 GQPESPRRLSLGQG---DSTEAATEERGPRARLSSATANALYSSNLRDDTKAILEQISAH 1050
G P PR + G + TE+ T +R P+ R AL + + T
Sbjct: 968 GPP--PRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPG-------- 1017
Query: 1051 GQKHRAVPAPSPGPTHNSPELGRP-------PAAGVLAP 1082
A P PSP P + P P PA GV P
Sbjct: 1018 ----PAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTP 1052
Score = 33.9 bits (76), Expect = 0.94
Identities = 47/164 (28%), Positives = 65/164 (39%), Gaps = 30/164 (18%)
Query: 549 PCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDGGDDGLPAPM-EAE 607
P + ++ GP P P E G EG G RR R S +G G PAP A
Sbjct: 873 PKRLSSVSGPSPEPPPLDESPGPKEGATGPRR-RTLSEPAG----PSEPPGPPAPAGPAS 927
Query: 608 AYEDDVLAPGGRAP----AGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGPEEPG-- 661
E++ P G P +G+ LP A + GP P RE P PG
Sbjct: 928 DTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP------PPRETPVPPGLD 981
Query: 662 --LAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAAT 703
L + D+ + R P + L+++L+ A G A+AT
Sbjct: 982 FNLTESDTVKRR--PKCREREPLQTALL--------AFGVASAT 1015
Score = 31.2 bits (69), Expect = 6.1
Identities = 119/550 (21%), Positives = 170/550 (30%), Gaps = 77/550 (14%)
Query: 464 LTPARP---QGLFEKLRGGRAGFADPDDFTLGAGPRFPELG--PDGHQRLDYVPSSASRE 518
L PAR + + + RG P G P P+ P+G +R P S
Sbjct: 690 LPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTER---PPKLCSSL 746
Query: 519 VRHGSDPAFAPGPRGLEPSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGL 578
G P P+G S AP P + A P P P+RR R G
Sbjct: 747 PGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPG- 805
Query: 579 RRWRLASYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPT 638
G+ G+ P +Y P GR+ PS PA
Sbjct: 806 ----------PTEGDAEGEAEGPVGSTLGSYATLTRRP-GRSALVRTSPSVTPTPAR--- 851
Query: 639 KVPVPGPGSGGNGPEREGPEEPGLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAG 698
P S R+GP P + S V S L S EGA G
Sbjct: 852 --GTPRSQSFALRARRKGPPPPPPKRLSS--------VSGPSPEPPPLDESPGPKEGATG 901
Query: 699 AAAATEKVQLLHKEQTVSETLGPGGEAVRSAASTKVAELLEKYKGPARDP---GGGAGAI 755
+ +T+SE GP A + ++ E+ GP P G +
Sbjct: 902 P-----------RRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGL 950
Query: 756 TVASHSKAVVSQAWREEVAAPGAVGGERRSLESCLLDLRDSFAQQLHQE---AERQPGAA 812
A + Q R + A P R + LD + + + + ER+P
Sbjct: 951 PFAEEGNLTIKQ--RPKPAGP----PPRETPVPPGLDFNLTESDTVKRRPKCREREPLQT 1004
Query: 813 SLTAAQLLDTLGRSGSDRLPSRFLSAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPT 872
+L A G + + P+ L + + SP P P S Q + SP
Sbjct: 1005 ALLA------FGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSP- 1057
Query: 873 SAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPVPERRSSPVPPVPE 932
+ P P PG + S G E +P + + VP ++P PV
Sbjct: 1058 AMQPPVPPCPGPGLESSAASRWNGETEPPAAPAA---------LLKVPGAGTAP-KPVSV 1107
Query: 933 RRGSLTLTISGESPKAGPAEEGPSGPMEVLRKG----SLRLRQLLSPKGERRMEDEGGFP 988
L + +P+ GP P P G RL Q S E
Sbjct: 1108 ACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIG 1167
Query: 989 VPQENGQPES 998
++ G P +
Sbjct: 1168 TKEQEGTPSA 1177
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 46.6 bits (109), Expect = 1e-04
Identities = 63/212 (29%), Positives = 83/212 (39%), Gaps = 28/212 (13%)
Query: 876 PERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPVPERRSSPVPPVPERRG 935
PER SP+ G+S++ G+PT + KG + P G PP PER +S P
Sbjct: 574 PERTLSPSSGYSSQSGTPT---LPPKG--LAGPPASPGKAQPPKPERVTSLRSPGASVSS 628
Query: 936 SLTLTISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQ 995
SLT S S PA SGP Q+L+P G+R + VP
Sbjct: 629 SLTSLCSSSS---DPAPSDRSGP------------QILTPLGDRFVIPPHP-KVPAPFSP 672
Query: 996 PESPRRLSLGQGDSTEAATEERGPRARLSSATANALYSSNLRDDTKAILEQISAHGQKHR 1055
P S R + A GP +T +A S T Q S K +
Sbjct: 673 PPSKPRSPNPAAPALAAPAVVPGP-----VSTTDASPQSPPTPQTTLTPLQESPVISKDQ 727
Query: 1056 AVPAPSPGPT-HNSPELGRPPAAGVLAPDMSD 1086
+ P PSP P+ H P + P V AP S+
Sbjct: 728 S-PPPSPPPSYHPPPPPTKKPEVVVEAPSASE 758
Score = 42.7 bits (99), Expect = 0.002
Identities = 115/482 (23%), Positives = 159/482 (32%), Gaps = 80/482 (16%)
Query: 654 REGPEEPGLAKQDSFRSRLN-PLVQRSSRLRSSL--IFSTSQAEGAAGAAAATEKVQLLH 710
R E PG + R + P V R S + S E A A A TE + H
Sbjct: 236 RNEREAPGTPRAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRH 295
Query: 711 KEQTVSETLGPGGEAVRSAASTKVAELLEKYKGPARDPGGGAGAITVASHSKAVVSQAWR 770
++ + G + T+ L GGAG S + ++ QA
Sbjct: 296 IDRVYRDDTFVG-----RSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATY 350
Query: 771 EEVAAPGAV---GGERRSLESCLLDLRDSFAQQLHQEAERQPGAASLTAAQLLDTLGRSG 827
P AV + +L C LR LH +AS + + L
Sbjct: 351 LSKLIPHAVLPPTVDVVALGRC--SLRTLSRCSLH--------SASPASVRSLGRFSSVS 400
Query: 828 SDRLPSRFLSAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFS 887
S + SR S+ S + S + +GS S+G P S+ P P
Sbjct: 401 SPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSS--KGGSEGQPESSTASNSVVPPPQGG 458
Query: 888 TRRGSPTTG---------FIEQKGSPTSAYPERRGSPVPPVPERRSSP------------ 926
+ RGSP+ G I G + R PP P RR+
Sbjct: 459 SGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGP 518
Query: 927 --VPPVPERRGSLTL---TISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERR- 980
+PP PER+ L +G S AG A P P G LSP G RR
Sbjct: 519 LGLPPKPERKQQPQLPRPPTTGGSEGAG-AAPCPPNPANSWVPG-------LSPGGSRRP 570
Query: 981 -------------MEDEGGFPVPQENGQPESPRRLSLGQGDSTEAATEERGPRARLSSA- 1026
+ G P G P Q E T R P A +SS+
Sbjct: 571 PRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSL 630
Query: 1027 TANALYSSNLRDDTKAILEQISAHGQK-----HRAVPAP-SPGPTHNSPELGRPPAAGVL 1080
T+ SS+ ++ + ++ G + H VPAP SP P + P P A +
Sbjct: 631 TSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP--SKPRSPNPAAPALA 688
Query: 1081 AP 1082
AP
Sbjct: 689 AP 690
Score = 31.2 bits (69), Expect = 6.1
Identities = 52/200 (26%), Positives = 68/200 (34%), Gaps = 42/200 (21%)
Query: 456 QQYQWDPQLTPARPQGLFEKLRGGRAGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSA 515
Q W P PA E+ A F P++ P GP G L P+++
Sbjct: 765 QDPNWPPPPPPAP-----EEQDLSMADFPPPEEAFFSVASPEPA-GPSGSPELVSSPAAS 818
Query: 516 SREVRHGSDPAFAPGPRGLEPSGAPRPNLTQRFPCQAAARPG-PDPAPEAEP---ERRGG 571
S ++P G+P P P A++ PG P+ EP + GG
Sbjct: 819 SSSAT----------ALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGG 868
Query: 572 PEGRAGLRRWRLASYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFR 631
P ED G + + V APGG AP L PSA +
Sbjct: 869 PP------------------REDVGAPLVTPSLLQMVRLRSVGAPGG-APTPALGPSAPQ 909
Query: 632 VP---AAFPTKVPVPGPGSG 648
P A PVP P SG
Sbjct: 910 KPLRRALSGRASPVPAPSSG 929
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 46.2 bits (108), Expect = 2e-04
Identities = 59/235 (25%), Positives = 87/235 (37%), Gaps = 43/235 (18%)
Query: 872 TSAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPVPERRSSPVPPVP 931
T + P R+ SP+P RR SP I+++ SP S P+RR + PP P+RR+SP PP P
Sbjct: 581 TPSPPPRRRSPSP----RRYSPP---IQRRYSP-SPPPKRRTASPPPPPKRRASPSPP-P 631
Query: 932 ERRGS--------LTLTISGESPKAGPAEEGPSGPMEVLRKG-SLRLRQLLSPKGERRME 982
+RR S + SP S P R+ S + + SP R
Sbjct: 632 KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP 691
Query: 983 DEGGFPVPQENGQPESPRRLSLGQGDSTEAATEERGPRAR-LSSATANALYSSNLRDDTK 1041
P P G SP+R + R P + + A + + S ++
Sbjct: 692 QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSR 751
Query: 1042 AILEQISAHGQKHRAVPAP------------------------SPGPTHNSPELG 1072
++ +K A P+P SP P NS + G
Sbjct: 752 SVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEG 806
Score = 42.7 bits (99), Expect = 0.002
Identities = 57/212 (26%), Positives = 83/212 (39%), Gaps = 25/212 (11%)
Query: 864 HNESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPVPERR 923
H+ S+ + S P ++ T RR SP+ ++ SP+ A P RR P P RR
Sbjct: 523 HSPSRSASPS--PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRR-RRTPTPPPRR 579
Query: 924 SSPVPPVPERRGSLTLTISGE-----SPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGE 978
+P PP P RR S SP P S P R+ S SP +
Sbjct: 580 RTPSPP-PRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRAS------PSPPPK 632
Query: 979 RRMEDEGGFPVPQENGQPESPRRL-SLG----QGDSTEAATEE-RGPRARLSSATANALY 1032
RR+ P P++ P + RR SL +G S +T E R P+ + +
Sbjct: 633 RRVSHS---PPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 689
Query: 1033 SSNLRDDTKAILEQISAHGQKHRAVPAPSPGP 1064
+ + S+ Q+ R P+PS P
Sbjct: 690 APQTSSSPPPVRRGASSSPQR-RQSPSPSTRP 720
Score = 41.6 bits (96), Expect = 0.005
Identities = 50/219 (22%), Positives = 85/219 (38%), Gaps = 20/219 (9%)
Query: 869 GSPTSAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPV---PERRSS 925
GS +S+ R SP R SP ++ SP+++ P RR P PP P+ R S
Sbjct: 357 GSSSSSSSSRSRSPPKKPPKRTSSPPRK--TRRLSPSASPPRRRHRPSPPATPPPKTRHS 414
Query: 926 PVPPVPERRGSLTLTI-----SGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERR 980
P P R +++ SG+ K E+ S P + + L + KG +
Sbjct: 415 PTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRES-PSPAPKPRKVELSESEEDKGGKM 473
Query: 981 MEDEGGFPVPQENGQPESPRRLSLGQGDSTEAATEERGPRARLSSATANALY----SSNL 1036
+ Q+ Q + S S+ ++ +ER R+ + + S +
Sbjct: 474 AAADS----VQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSA 529
Query: 1037 RDDTKAILEQISAHGQKHRAVPAPSPGPTHNSPELGRPP 1075
+ ++ S G++ R+ P+P P SP PP
Sbjct: 530 SPSPRKRQKETSPRGRRRRS-PSPPPTRRRRSPSPAPPP 567
Score = 37.0 bits (84), Expect = 0.11
Identities = 38/140 (27%), Positives = 52/140 (37%), Gaps = 22/140 (15%)
Query: 840 SHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIE 899
SHS P+ SP+ S + H KGS S SP P SP +
Sbjct: 636 SHSPPPKQRSSPVTKRRSPSLSSKHR--KGSSPSRSTREARSPQPN-KRHSPSPRPRAPQ 692
Query: 900 QKGSP------TSAYPERRGSPVP-----------PVPERRSSPVPPVPE--RRGSLTLT 940
SP S+ P+RR SP P P P++ P P+ RR S + +
Sbjct: 693 TSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRS 752
Query: 941 ISGESPKAGPAEEGPSGPME 960
+SG A P P++
Sbjct: 753 VSGSPEPAAKKPPAPPSPVQ 772
Score = 35.4 bits (80), Expect = 0.32
Identities = 45/173 (26%), Positives = 69/173 (39%), Gaps = 10/173 (5%)
Query: 906 SAYPERRGSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPMEVLRKG 965
S P RR S P P RRSSPV +R S + +S PA E E L +
Sbjct: 169 SRSPRRRKSRSPS-PRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPE-LPEP 226
Query: 966 SLRLRQLLSPKGERRMEDEGGFPVPQENGQPESPRRLSLGQGDSTEAATEERGPRARLSS 1025
S+++++ P + VP+ PE P+ S + E E+ PR+R S
Sbjct: 227 SVKVKE---PSVQEATSTSDILKVPKPEPIPE-PKEPSPEKNSKKEKEKEKTRPRSRSRS 282
Query: 1026 ATANALYS---SNLRDDTKAILEQISAHGQKHRAVPAPSPGPTHNSPELGRPP 1075
+ + S S+ R + + ++ + R P P P +P PP
Sbjct: 283 KSRSRTRSRSPSHTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP 334
Score = 34.7 bits (78), Expect = 0.55
Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 22/140 (15%)
Query: 909 PERRGSPVPPVPERRSSPVP-------PVPERRGSLTLTISGESPKA------GPAEEGP 955
P RR SP P RR P P PV RR S + ++SG S + P ++ P
Sbjct: 317 PRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRS-SASLSGSSSSSSSSRSRSPPKKPP 375
Query: 956 SGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESPR-------RLSLGQGD 1008
RK + RL SP R P P+ P + R+S+ G
Sbjct: 376 KRTSSPPRK-TRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGR 434
Query: 1009 STEAATEERGPRARLSSATA 1028
++ T+ +G R S + A
Sbjct: 435 TSGKVTKHKGTEKRESPSPA 454
Score = 33.1 bits (74), Expect = 1.6
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
Query: 514 SASREVRHGSDPAFA--PGPRGLEPSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGG 571
S+SR V +PA P P S +P N + P + A P P P+P ++ GG
Sbjct: 748 SSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGG 807
Score = 31.6 bits (70), Expect = 4.7
Identities = 30/131 (22%), Positives = 47/131 (35%), Gaps = 9/131 (6%)
Query: 832 PSRFLSAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRG 891
P++ S +PQ SP P+ + +S T +P P +
Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737
Query: 892 SPTTGFIEQKGSPTSA----YPERRGSPVPPVPERRSSP----VPPVPERRGSLTLTISG 943
SP+ + + S S P + P PP P + SP P VP ++ + T S
Sbjct: 738 SPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAK-SPTPSP 796
Query: 944 ESPKAGPAEEG 954
P+ E G
Sbjct: 797 SPPRNSDQEGG 807
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
sapiens]
Length = 1650
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/176 (28%), Positives = 64/176 (36%), Gaps = 19/176 (10%)
Query: 501 GPDGHQRLDYVPSSASREVRHGS--DPAF--APGPRG----LEPSGAPRPNLTQRFPCQA 552
GP G + P S R+ G+ DP APG G P+G P P+ + P
Sbjct: 1229 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1288
Query: 553 AARPGPDPAPEAEPERRGGPEGRAGLRRWRLASY---------LSGCHGEDG--GDDGLP 601
+ P +A P GP G GLR A L G GE G GD GLP
Sbjct: 1289 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1348
Query: 602 APMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGP 657
P + + ++ PG P G P PA GPG +GP
Sbjct: 1349 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP 1404
Score = 44.3 bits (103), Expect = 7e-04
Identities = 53/174 (30%), Positives = 66/174 (37%), Gaps = 36/174 (20%)
Query: 501 GPDGHQRLDYVPSSASREVRHGS----DPAFAPGPRG-LEPSGAPRPNLTQRFPCQAAAR 555
GP G L +P + + G P PGPRG P+GA P + P
Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP----QGPPGGVGN 1119
Query: 556 PGPDPAPEAEPERRGGP--EGRAGLRRWRLASYLSGCHGEDG--GDDGLPAPMEAEAYED 611
GP P + EP G P +G G++ R G GE G G G P P
Sbjct: 1120 LGP-PGEKGEPGESGSPGIQGEPGVKGPR------GERGEKGESGQPGEPGP-------- 1164
Query: 612 DVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGS--GGNGPEREGPE--EPG 661
PG + P GD P P FP PG G G +G + + E EPG
Sbjct: 1165 ----PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1214
Score = 39.7 bits (91), Expect = 0.017
Identities = 68/247 (27%), Positives = 87/247 (35%), Gaps = 43/247 (17%)
Query: 466 PARPQGLFEKLRGGRAGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDP 525
P P EK G +G + P GPR + GP G S ++ G P
Sbjct: 730 PGFPGASGEKGARGLSGKSGPRGERGPTGPR-GQRGPRGA-----TGKSGAKGTSGGDGP 783
Query: 526 AFAPGPRGLE----PSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRW 581
PG RGL P+G P P P + P E + + GP G G+
Sbjct: 784 HGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGP 843
Query: 582 RLASYLSGCHGEDG--------GDDGLPAPMEAEAYEDDVL---APGGRAPAGDL----- 625
+ A+ +G GE G G+ GLP E + D APG PAG
Sbjct: 844 QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 903
Query: 626 --LPSAFRVPAAFPTKVPV--PGP----------GSGG--NGPEREGPE-EPGLAKQDSF 668
LP P + P PGP GSGG P R GP+ PG A +
Sbjct: 904 RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGV 963
Query: 669 RSRLNPL 675
P+
Sbjct: 964 PGEKGPI 970
Score = 38.1 bits (87), Expect = 0.050
Identities = 45/154 (29%), Positives = 55/154 (35%), Gaps = 23/154 (14%)
Query: 529 PGPRGLEPSGAPRPNLT-QRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYL 587
PG G P+ +L FP + + + ++ P GP G G R R A+
Sbjct: 712 PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGK 771
Query: 588 SGCHGEDGGDD--------GLPAPMEAEAYEDDVLAPGGRAPAGDLLPS--AFRVPAAFP 637
SG G GGD GLP P + PG P D LP R F
Sbjct: 772 SGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPG--PPGKDGLPGHPGQRGEVGFQ 829
Query: 638 TKVPVPGP--------GSGGNGP--EREGPEEPG 661
K PGP +G GP ER P PG
Sbjct: 830 GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 863
Score = 37.0 bits (84), Expect = 0.11
Identities = 121/528 (22%), Positives = 157/528 (29%), Gaps = 76/528 (14%)
Query: 501 GPDGHQRLDYVPSSASREVRHGSD-PAFAPG---PRGLE--PSGAPRPNLTQRFPCQAAA 554
GP G Q L P +A +E G P APG P GL P P +
Sbjct: 863 GPPGEQGL---PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 919
Query: 555 RPGPDPAPEAEPERRG--------GPEGRAGLRRWRLASYLSGCHGEDG--GDDGLPAPM 604
P P P P RG GP GR G + G GE G G+ G P
Sbjct: 920 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG------PPGAAGEKGVPGEKGPIGPT 973
Query: 605 EAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGP----EEP 660
+ + V PG P G + P + G P GP +P
Sbjct: 974 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1033
Query: 661 GLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHKEQTVSETLG 720
G A D P F EG G + L G
Sbjct: 1034 GAAGADGEPGARGPQGH----------FGAKGDEGTRGFNGPPGPIGL-------QGLPG 1076
Query: 721 PGGEAVRSAASTKVAELLEKYKGPARDPGGGAGAITVASHSKAVVSQAWREEVAAPGAVG 780
P GE + V + R P G GA V + E PG G
Sbjct: 1077 PSGE---KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1133
Query: 781 GERRSLESCLLDLRDSFAQQLHQEAERQPGAASLTAAQLLD-TLGRSGSDRLPSRFLSAQ 839
E + R ++ +PG D G G P
Sbjct: 1134 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG------ 1187
Query: 840 SHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIE 899
P G P +G+ + E G P S P + P PG +RG + E
Sbjct: 1188 --DPGPPGEGGPRGQDGAKGDRGEDGEP-GQPGSPGPTGENGP-PGPLGKRGPAGSPGSE 1243
Query: 900 --QKGSPTSAYPERRGSPVPPVPERRSSPV-PPVPERRGSLTLTISGESPKAGPAEEGPS 956
Q G P G+P P + P P P+ L ++ + + GP
Sbjct: 1244 GRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP 1303
Query: 957 GP-----MEVLR--------KGSLRLRQLLSPKGERRMEDEGGFPVPQ 991
GP + LR KG L L+ P GE+ + + G P PQ
Sbjct: 1304 GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ 1351
Score = 36.2 bits (82), Expect = 0.19
Identities = 52/179 (29%), Positives = 62/179 (34%), Gaps = 35/179 (19%)
Query: 501 GPDGHQRLDYVPSSASREVRHGSDPA-------FAPGPRGLEPSGAPRPNLTQRFPCQAA 553
GP G Q L P A R R G+D A G RG + R A
Sbjct: 434 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 493
Query: 554 ARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDG--------GDDGLPAPME 605
PGP P + ER G +G G R G GE G G G+P P
Sbjct: 494 GLPGP---PGEDGER--GDDGEIGPR---------GLPGESGPRGLLGPKGPPGIPGPPG 539
Query: 606 AEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPERE-GPE-EPGL 662
+ G P G+ P P +PGP G GP E GP+ +PGL
Sbjct: 540 VRGMDGPQGPKGSLGPQGEPGPPG---QQGTPGTQGLPGP-QGAIGPHGEKGPQGKPGL 594
Score = 33.1 bits (74), Expect = 1.6
Identities = 42/141 (29%), Positives = 54/141 (38%), Gaps = 27/141 (19%)
Query: 525 PAFAPGPRGLEPSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLA 584
PA GP G++ + P + +R P A PG D AP GP G + + +R
Sbjct: 320 PAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAP--------GPPGTSLMLPFRF- 370
Query: 585 SYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPG 644
G GGD G P EA +L A G P + P + PG
Sbjct: 371 -------GSGGGDKG-PVVAAQEAQAQAILQQARLALRGPPGPMGY---TGRPGPLGQPG 419
Query: 645 -PG----SGGNGPEREGPEEP 660
PG SG GP +GP P
Sbjct: 420 SPGLKGESGDLGP--QGPRGP 438
Score = 32.0 bits (71), Expect = 3.6
Identities = 54/211 (25%), Positives = 68/211 (32%), Gaps = 39/211 (18%)
Query: 809 PGAASLTAAQLLDTLGRSGSDRLPSRFLSAQSHSTSPQGLDSPLPLEG-SGAHQVLHNES 867
PGA+ A+ L G+SG + T P+G P G SGA +
Sbjct: 733 PGASGEKGARGLS--GKSGP--------RGERGPTGPRGQRGPRGATGKSGAKGTSGGDG 782
Query: 868 KGSPT-----------SAYPERKGSP-------TPGFSTRRGSPT-TGFIEQKGSPTSAY 908
P + +P KG P PG +RG G G P
Sbjct: 783 PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 842
Query: 909 PERRGSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPMEVLRKGSLR 968
P+ P+ ER P PP P L T E K P G G + G
Sbjct: 843 PQGAAGETGPMGER-GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG-----KDGPAG 896
Query: 969 LRQLLSPKGERRMEDEGGFPVPQENGQPESP 999
LR GER + G P + N P P
Sbjct: 897 LRGF---PGERGLPGTAGGPGLKGNEGPSGP 924
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
sapiens]
Length = 1629
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/176 (28%), Positives = 64/176 (36%), Gaps = 19/176 (10%)
Query: 501 GPDGHQRLDYVPSSASREVRHGS--DPAF--APGPRG----LEPSGAPRPNLTQRFPCQA 552
GP G + P S R+ G+ DP APG G P+G P P+ + P
Sbjct: 1208 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1267
Query: 553 AARPGPDPAPEAEPERRGGPEGRAGLRRWRLASY---------LSGCHGEDG--GDDGLP 601
+ P +A P GP G GLR A L G GE G GD GLP
Sbjct: 1268 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1327
Query: 602 APMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGP 657
P + + ++ PG P G P PA GPG +GP
Sbjct: 1328 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP 1383
Score = 44.3 bits (103), Expect = 7e-04
Identities = 53/174 (30%), Positives = 66/174 (37%), Gaps = 36/174 (20%)
Query: 501 GPDGHQRLDYVPSSASREVRHGS----DPAFAPGPRG-LEPSGAPRPNLTQRFPCQAAAR 555
GP G L +P + + G P PGPRG P+GA P + P
Sbjct: 1043 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP----QGPPGGVGN 1098
Query: 556 PGPDPAPEAEPERRGGP--EGRAGLRRWRLASYLSGCHGEDG--GDDGLPAPMEAEAYED 611
GP P + EP G P +G G++ R G GE G G G P P
Sbjct: 1099 LGP-PGEKGEPGESGSPGIQGEPGVKGPR------GERGEKGESGQPGEPGP-------- 1143
Query: 612 DVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGS--GGNGPEREGPE--EPG 661
PG + P GD P P FP PG G G +G + + E EPG
Sbjct: 1144 ----PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193
Score = 39.7 bits (91), Expect = 0.017
Identities = 68/247 (27%), Positives = 87/247 (35%), Gaps = 43/247 (17%)
Query: 466 PARPQGLFEKLRGGRAGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDP 525
P P EK G +G + P GPR + GP G S ++ G P
Sbjct: 709 PGFPGASGEKGARGLSGKSGPRGERGPTGPR-GQRGPRGA-----TGKSGAKGTSGGDGP 762
Query: 526 AFAPGPRGLE----PSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRW 581
PG RGL P+G P P P + P E + + GP G G+
Sbjct: 763 HGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGP 822
Query: 582 RLASYLSGCHGEDG--------GDDGLPAPMEAEAYEDDVL---APGGRAPAGDL----- 625
+ A+ +G GE G G+ GLP E + D APG PAG
Sbjct: 823 QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 882
Query: 626 --LPSAFRVPAAFPTKVPV--PGP----------GSGG--NGPEREGPE-EPGLAKQDSF 668
LP P + P PGP GSGG P R GP+ PG A +
Sbjct: 883 RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGV 942
Query: 669 RSRLNPL 675
P+
Sbjct: 943 PGEKGPI 949
Score = 38.1 bits (87), Expect = 0.050
Identities = 45/154 (29%), Positives = 55/154 (35%), Gaps = 23/154 (14%)
Query: 529 PGPRGLEPSGAPRPNLT-QRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYL 587
PG G P+ +L FP + + + ++ P GP G G R R A+
Sbjct: 691 PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGK 750
Query: 588 SGCHGEDGGDD--------GLPAPMEAEAYEDDVLAPGGRAPAGDLLPS--AFRVPAAFP 637
SG G GGD GLP P + PG P D LP R F
Sbjct: 751 SGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPG--PPGKDGLPGHPGQRGEVGFQ 808
Query: 638 TKVPVPGP--------GSGGNGP--EREGPEEPG 661
K PGP +G GP ER P PG
Sbjct: 809 GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 842
Score = 37.0 bits (84), Expect = 0.11
Identities = 121/528 (22%), Positives = 157/528 (29%), Gaps = 76/528 (14%)
Query: 501 GPDGHQRLDYVPSSASREVRHGSD-PAFAPG---PRGLE--PSGAPRPNLTQRFPCQAAA 554
GP G Q L P +A +E G P APG P GL P P +
Sbjct: 842 GPPGEQGL---PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 898
Query: 555 RPGPDPAPEAEPERRG--------GPEGRAGLRRWRLASYLSGCHGEDG--GDDGLPAPM 604
P P P P RG GP GR G + G GE G G+ G P
Sbjct: 899 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG------PPGAAGEKGVPGEKGPIGPT 952
Query: 605 EAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGP----EEP 660
+ + V PG P G + P + G P GP +P
Sbjct: 953 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1012
Query: 661 GLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHKEQTVSETLG 720
G A D P F EG G + L G
Sbjct: 1013 GAAGADGEPGARGPQGH----------FGAKGDEGTRGFNGPPGPIGL-------QGLPG 1055
Query: 721 PGGEAVRSAASTKVAELLEKYKGPARDPGGGAGAITVASHSKAVVSQAWREEVAAPGAVG 780
P GE + V + R P G GA V + E PG G
Sbjct: 1056 PSGE---KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1112
Query: 781 GERRSLESCLLDLRDSFAQQLHQEAERQPGAASLTAAQLLD-TLGRSGSDRLPSRFLSAQ 839
E + R ++ +PG D G G P
Sbjct: 1113 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG------ 1166
Query: 840 SHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIE 899
P G P +G+ + E G P S P + P PG +RG + E
Sbjct: 1167 --DPGPPGEGGPRGQDGAKGDRGEDGEP-GQPGSPGPTGENGP-PGPLGKRGPAGSPGSE 1222
Query: 900 --QKGSPTSAYPERRGSPVPPVPERRSSPV-PPVPERRGSLTLTISGESPKAGPAEEGPS 956
Q G P G+P P + P P P+ L ++ + + GP
Sbjct: 1223 GRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP 1282
Query: 957 GP-----MEVLR--------KGSLRLRQLLSPKGERRMEDEGGFPVPQ 991
GP + LR KG L L+ P GE+ + + G P PQ
Sbjct: 1283 GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ 1330
Score = 36.2 bits (82), Expect = 0.19
Identities = 52/179 (29%), Positives = 62/179 (34%), Gaps = 35/179 (19%)
Query: 501 GPDGHQRLDYVPSSASREVRHGSDPA-------FAPGPRGLEPSGAPRPNLTQRFPCQAA 553
GP G Q L P A R R G+D A G RG + R A
Sbjct: 413 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 472
Query: 554 ARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDG--------GDDGLPAPME 605
PGP P + ER G +G G R G GE G G G+P P
Sbjct: 473 GLPGP---PGEDGER--GDDGEIGPR---------GLPGESGPRGLLGPKGPPGIPGPPG 518
Query: 606 AEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPERE-GPE-EPGL 662
+ G P G+ P P +PGP G GP E GP+ +PGL
Sbjct: 519 VRGMDGPQGPKGSLGPQGEPGPPG---QQGTPGTQGLPGP-QGAIGPHGEKGPQGKPGL 573
Score = 33.1 bits (74), Expect = 1.6
Identities = 42/141 (29%), Positives = 54/141 (38%), Gaps = 27/141 (19%)
Query: 525 PAFAPGPRGLEPSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLA 584
PA GP G++ + P + +R P A PG D AP GP G + + +R
Sbjct: 299 PAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAP--------GPPGTSLMLPFRF- 349
Query: 585 SYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPG 644
G GGD G P EA +L A G P + P + PG
Sbjct: 350 -------GSGGGDKG-PVVAAQEAQAQAILQQARLALRGPPGPMGY---TGRPGPLGQPG 398
Query: 645 -PG----SGGNGPEREGPEEP 660
PG SG GP +GP P
Sbjct: 399 SPGLKGESGDLGP--QGPRGP 417
Score = 32.0 bits (71), Expect = 3.6
Identities = 54/211 (25%), Positives = 68/211 (32%), Gaps = 39/211 (18%)
Query: 809 PGAASLTAAQLLDTLGRSGSDRLPSRFLSAQSHSTSPQGLDSPLPLEG-SGAHQVLHNES 867
PGA+ A+ L G+SG + T P+G P G SGA +
Sbjct: 712 PGASGEKGARGLS--GKSGP--------RGERGPTGPRGQRGPRGATGKSGAKGTSGGDG 761
Query: 868 KGSPT-----------SAYPERKGSP-------TPGFSTRRGSPT-TGFIEQKGSPTSAY 908
P + +P KG P PG +RG G G P
Sbjct: 762 PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 821
Query: 909 PERRGSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPMEVLRKGSLR 968
P+ P+ ER P PP P L T E K P G G + G
Sbjct: 822 PQGAAGETGPMGER-GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG-----KDGPAG 875
Query: 969 LRQLLSPKGERRMEDEGGFPVPQENGQPESP 999
LR GER + G P + N P P
Sbjct: 876 LRGF---PGERGLPGTAGGPGLKGNEGPSGP 903
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/176 (28%), Positives = 64/176 (36%), Gaps = 19/176 (10%)
Query: 501 GPDGHQRLDYVPSSASREVRHGS--DPAF--APGPRG----LEPSGAPRPNLTQRFPCQA 552
GP G + P S R+ G+ DP APG G P+G P P+ + P
Sbjct: 1315 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1374
Query: 553 AARPGPDPAPEAEPERRGGPEGRAGLRRWRLASY---------LSGCHGEDG--GDDGLP 601
+ P +A P GP G GLR A L G GE G GD GLP
Sbjct: 1375 GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1434
Query: 602 APMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGP 657
P + + ++ PG P G P PA GPG +GP
Sbjct: 1435 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP 1490
Score = 44.3 bits (103), Expect = 7e-04
Identities = 53/174 (30%), Positives = 66/174 (37%), Gaps = 36/174 (20%)
Query: 501 GPDGHQRLDYVPSSASREVRHGS----DPAFAPGPRG-LEPSGAPRPNLTQRFPCQAAAR 555
GP G L +P + + G P PGPRG P+GA P + P
Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP----QGPPGGVGN 1205
Query: 556 PGPDPAPEAEPERRGGP--EGRAGLRRWRLASYLSGCHGEDG--GDDGLPAPMEAEAYED 611
GP P + EP G P +G G++ R G GE G G G P P
Sbjct: 1206 LGP-PGEKGEPGESGSPGIQGEPGVKGPR------GERGEKGESGQPGEPGP-------- 1250
Query: 612 DVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGS--GGNGPEREGPE--EPG 661
PG + P GD P P FP PG G G +G + + E EPG
Sbjct: 1251 ----PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1300
Score = 39.7 bits (91), Expect = 0.017
Identities = 68/247 (27%), Positives = 87/247 (35%), Gaps = 43/247 (17%)
Query: 466 PARPQGLFEKLRGGRAGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGSDP 525
P P EK G +G + P GPR + GP G S ++ G P
Sbjct: 816 PGFPGASGEKGARGLSGKSGPRGERGPTGPR-GQRGPRGA-----TGKSGAKGTSGGDGP 869
Query: 526 AFAPGPRGLE----PSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRW 581
PG RGL P+G P P P + P E + + GP G G+
Sbjct: 870 HGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGP 929
Query: 582 RLASYLSGCHGEDG--------GDDGLPAPMEAEAYEDDVL---APGGRAPAGDL----- 625
+ A+ +G GE G G+ GLP E + D APG PAG
Sbjct: 930 QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 989
Query: 626 --LPSAFRVPAAFPTKVPV--PGP----------GSGG--NGPEREGPE-EPGLAKQDSF 668
LP P + P PGP GSGG P R GP+ PG A +
Sbjct: 990 RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGV 1049
Query: 669 RSRLNPL 675
P+
Sbjct: 1050 PGEKGPI 1056
Score = 38.1 bits (87), Expect = 0.050
Identities = 45/154 (29%), Positives = 55/154 (35%), Gaps = 23/154 (14%)
Query: 529 PGPRGLEPSGAPRPNLT-QRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYL 587
PG G P+ +L FP + + + ++ P GP G G R R A+
Sbjct: 798 PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGK 857
Query: 588 SGCHGEDGGDD--------GLPAPMEAEAYEDDVLAPGGRAPAGDLLPS--AFRVPAAFP 637
SG G GGD GLP P + PG P D LP R F
Sbjct: 858 SGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPG--PPGKDGLPGHPGQRGEVGFQ 915
Query: 638 TKVPVPGP--------GSGGNGP--EREGPEEPG 661
K PGP +G GP ER P PG
Sbjct: 916 GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 949
Score = 37.0 bits (84), Expect = 0.11
Identities = 121/528 (22%), Positives = 157/528 (29%), Gaps = 76/528 (14%)
Query: 501 GPDGHQRLDYVPSSASREVRHGSD-PAFAPG---PRGLE--PSGAPRPNLTQRFPCQAAA 554
GP G Q L P +A +E G P APG P GL P P +
Sbjct: 949 GPPGEQGL---PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 1005
Query: 555 RPGPDPAPEAEPERRG--------GPEGRAGLRRWRLASYLSGCHGEDG--GDDGLPAPM 604
P P P P RG GP GR G + G GE G G+ G P
Sbjct: 1006 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG------PPGAAGEKGVPGEKGPIGPT 1059
Query: 605 EAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGP----EEP 660
+ + V PG P G + P + G P GP +P
Sbjct: 1060 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1119
Query: 661 GLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHKEQTVSETLG 720
G A D P F EG G + L G
Sbjct: 1120 GAAGADGEPGARGPQGH----------FGAKGDEGTRGFNGPPGPIGL-------QGLPG 1162
Query: 721 PGGEAVRSAASTKVAELLEKYKGPARDPGGGAGAITVASHSKAVVSQAWREEVAAPGAVG 780
P GE + V + R P G GA V + E PG G
Sbjct: 1163 PSGE---KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESG 1219
Query: 781 GERRSLESCLLDLRDSFAQQLHQEAERQPGAASLTAAQLLD-TLGRSGSDRLPSRFLSAQ 839
E + R ++ +PG D G G P
Sbjct: 1220 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG------ 1273
Query: 840 SHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIE 899
P G P +G+ + E G P S P + P PG +RG + E
Sbjct: 1274 --DPGPPGEGGPRGQDGAKGDRGEDGEP-GQPGSPGPTGENGP-PGPLGKRGPAGSPGSE 1329
Query: 900 --QKGSPTSAYPERRGSPVPPVPERRSSPV-PPVPERRGSLTLTISGESPKAGPAEEGPS 956
Q G P G+P P + P P P+ L ++ + + GP
Sbjct: 1330 GRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP 1389
Query: 957 GP-----MEVLR--------KGSLRLRQLLSPKGERRMEDEGGFPVPQ 991
GP + LR KG L L+ P GE+ + + G P PQ
Sbjct: 1390 GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ 1437
Score = 36.2 bits (82), Expect = 0.19
Identities = 52/179 (29%), Positives = 62/179 (34%), Gaps = 35/179 (19%)
Query: 501 GPDGHQRLDYVPSSASREVRHGSDPA-------FAPGPRGLEPSGAPRPNLTQRFPCQAA 553
GP G Q L P A R R G+D A G RG + R A
Sbjct: 520 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 579
Query: 554 ARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDG--------GDDGLPAPME 605
PGP P + ER G +G G R G GE G G G+P P
Sbjct: 580 GLPGP---PGEDGER--GDDGEIGPR---------GLPGESGPRGLLGPKGPPGIPGPPG 625
Query: 606 AEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPERE-GPE-EPGL 662
+ G P G+ P P +PGP G GP E GP+ +PGL
Sbjct: 626 VRGMDGPQGPKGSLGPQGEPGPPG---QQGTPGTQGLPGP-QGAIGPHGEKGPQGKPGL 680
Score = 33.1 bits (74), Expect = 1.6
Identities = 42/141 (29%), Positives = 54/141 (38%), Gaps = 27/141 (19%)
Query: 525 PAFAPGPRGLEPSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLA 584
PA GP G++ + P + +R P A PG D AP GP G + + +R
Sbjct: 406 PAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAP--------GPPGTSLMLPFRF- 456
Query: 585 SYLSGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPG 644
G GGD G P EA +L A G P + P + PG
Sbjct: 457 -------GSGGGDKG-PVVAAQEAQAQAILQQARLALRGPPGPMGY---TGRPGPLGQPG 505
Query: 645 -PG----SGGNGPEREGPEEP 660
PG SG GP +GP P
Sbjct: 506 SPGLKGESGDLGP--QGPRGP 524
Score = 32.0 bits (71), Expect = 3.6
Identities = 54/211 (25%), Positives = 68/211 (32%), Gaps = 39/211 (18%)
Query: 809 PGAASLTAAQLLDTLGRSGSDRLPSRFLSAQSHSTSPQGLDSPLPLEG-SGAHQVLHNES 867
PGA+ A+ L G+SG + T P+G P G SGA +
Sbjct: 819 PGASGEKGARGLS--GKSGP--------RGERGPTGPRGQRGPRGATGKSGAKGTSGGDG 868
Query: 868 KGSPT-----------SAYPERKGSP-------TPGFSTRRGSPT-TGFIEQKGSPTSAY 908
P + +P KG P PG +RG G G P
Sbjct: 869 PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 928
Query: 909 PERRGSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPMEVLRKGSLR 968
P+ P+ ER P PP P L T E K P G G + G
Sbjct: 929 PQGAAGETGPMGER-GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG-----KDGPAG 982
Query: 969 LRQLLSPKGERRMEDEGGFPVPQENGQPESP 999
LR GER + G P + N P P
Sbjct: 983 LRGF---PGERGLPGTAGGPGLKGNEGPSGP 1010
>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
Length = 841
Score = 45.8 bits (107), Expect = 2e-04
Identities = 105/407 (25%), Positives = 149/407 (36%), Gaps = 85/407 (20%)
Query: 616 PGGRAPAGDLLPSAFRVPAAFP-----TKVPVPGPGSGGNGP--EREGPEEPGLAKQDSF 668
PGG A G S+ R P A P TK+ + GPGSG P ++ G ++P ++S
Sbjct: 98 PGG-ASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESS 156
Query: 669 RSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHKEQTVSETLGPGGEAVRS 728
R +RS + S+ F S G + +Q L + V+ G V +
Sbjct: 157 RKVPPQKPRRSPNTQLSVSFDESCPPGPS-PRGGNLPLQRLTRGSRVA-----GDPDVGA 210
Query: 729 AASTKVAELL-EKYKGPARDPGG------GAGAIT--VASHSKAVVSQAWREEVAAP-GA 778
E++ + ++G R GG G G T + S + S+A EE+ P
Sbjct: 211 QEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPE 270
Query: 779 VGGERRSLESCLLDLRDSFAQQLHQ---EAERQPGAASLTAAQLLDTLGRSGSDRLPSRF 835
GE R+ L S QQ H A R+P +A LPSR
Sbjct: 271 EAGEGRANGPPPLTAT-SPPQQPHALPPHAHRRPASA------------------LPSR- 310
Query: 836 LSAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKG-SPTPGFSTRRGSPT 894
T+P + P P +L + P A+P+ K S TPG R
Sbjct: 311 RDGTPTKTTPCEIPPPFP-------NLLQHRP---PLLAFPQAKSASRTPGDGVSRLPVL 360
Query: 895 TGFIEQKGSPTSAYPERRGSPVPPVP--ERRSSPVPPVPERRGSLTLTISGESPKAGPAE 952
E GS +P P VP ER + P PP P L L SG +
Sbjct: 361 CHSKEPAGS----------TPAPQVPARERETPPPPPPPPAANLLLLGPSGRA------- 403
Query: 953 EGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESP 999
S P+ G P+GER + + P+ G P +P
Sbjct: 404 RSHSTPLPPQGSG--------QPRGERELPNSHSMICPKAAGAPAAP 442
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 45.4 bits (106), Expect = 3e-04
Identities = 107/584 (18%), Positives = 194/584 (33%), Gaps = 70/584 (11%)
Query: 593 EDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGP 652
E+GG++ EAE E++ +P A A P K P P
Sbjct: 486 EEGGEEE-----EAEGGEEETKSPPAEEAASP------EKEAKSPVKEEAKSPAEA-KSP 533
Query: 653 EREGPEEPGLAKQDSFRSRLNPLVQRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHKE 712
E+E + P K S +P + + + +A+ A + EK + KE
Sbjct: 534 EKEEAKSPAEVK--SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPA-EVKSPEKAKSPAKE 590
Query: 713 QTVSETLGPGGEAVRSAASTKVAELLEKYKGPARDPGGGAGAITVASHSKAVVSQAWREE 772
+ S E +S + E K P ++ + +K+ + +
Sbjct: 591 EAKSPAEAKSPEKAKSPVKEEAKSPAEA-KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP 649
Query: 773 VAAPGAVGGERRSLESCLLDLRDSFAQQLHQEAERQPGAASLTAAQLLDTLGRSGSDRLP 832
A E +S E ++ A+ E + P A + + + + +
Sbjct: 650 EKAKSPEKEEAKSPEKAKSPVK---AEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE 706
Query: 833 SRFLSAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTPGFSTRRGS 892
+ + SP+ SP+ E + +S + PE+ SP + S
Sbjct: 707 KAKSPVKEEAKSPEKAKSPVKEEAKTPEKA---KSPVKEEAKSPEKAKSPEKAKTLDVKS 763
Query: 893 PT--TGFIEQKGSPTSAYPERRGSPVP-----------PVPERRSSPVPPVPERRGSLTL 939
P T E+ SP +PE+ SPV P+ E +P +P++ +
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823
Query: 940 TISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQP--E 997
E P+ +E P E + + + K E + E P +E +P E
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883
Query: 998 SPRRLSLGQGDSTEAATEERGPRARLSSATANALYSSNLRDDTKAILEQISAHGQKHRAV 1057
P+ EA EE + ++ + A +++D K K +
Sbjct: 884 KPKE------SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK----------PKEKTE 927
Query: 1058 PAPSPGPTHNSPELGRPPAAGVLAPDMSDKDKCSAIFRSDSLGTQGRLSRTLPASAEERD 1117
A + E +P AP+ D + A + T+ A A+E D
Sbjct: 928 VAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE--------AKAKEDD 979
Query: 1118 RLLRRMESMRKEKRVYSRFEVFCKKEEASSPGAGEGPAEEGTRD 1161
+ L + S K ++ ++ +S+ P E+ T D
Sbjct: 980 KTLSKEPSKPKAEKA---------EKSSSTDQKDSKPPEKATED 1014
>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
Length = 684
Score = 45.4 bits (106), Expect = 3e-04
Identities = 148/602 (24%), Positives = 189/602 (31%), Gaps = 128/602 (21%)
Query: 464 LTPARPQGLFEKLRGGRAGFADPDDFTLGAGPRFPELGPDGHQRLDYVPSSASREVRHGS 523
L P P GL K G G A G G R P GP G L P
Sbjct: 106 LGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPP-GPSGLPGLPGPPG---------- 154
Query: 524 DPAFAPGPRGLEPSGAPRPNLTQRFPCQAAARPGPDPAPEAEPERRG-----GPEGRAGL 578
P PG G+ P GA C + PGP P P P +G G +G G
Sbjct: 155 -PPGPPGHPGVLPEGATD------LQCPSICPPGP-PGPPGMPGFKGPTGYKGEQGEVGK 206
Query: 579 RRWRLASYLSGCHGEDG--GDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAF 636
G G+ G G GLP + + PG P GD P FR P
Sbjct: 207 ---------DGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGI 257
Query: 637 PTKVPVPGPGSGGNGPE----------REGPE----------EPGLAKQDSFRSRLNPLV 676
P P G GPE R GP+ EPG+ +D
Sbjct: 258 P-GAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDG--------- 307
Query: 677 QRSSRLRSSLIFSTSQAEGAAGAAAATEKVQLLHKEQTVSETLGPGGEAVRSAASTKVAE 736
+ + +G AG A + + G G + E
Sbjct: 308 -------QNGVPGLDGQKGEAGRNGAPGE----KGPNGLPGLPGRAGSKGEKGERGRAGE 356
Query: 737 LLEKYKGPARDPG-----GGAGAITVASHSKAVVSQAWREEVAAPGAVG--GERRSLESC 789
L E GP+ +PG G G A H + + + APG G G++ S+
Sbjct: 357 LGE--AGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDP 414
Query: 790 LLDLRDSFAQQLHQEAERQPGAASLTAAQLLDTLGRSGSDRLPSRFLSAQSHSTSPQGLD 849
L + +R PG AA G +GSD LP P GL
Sbjct: 415 GLPGPQGLRGDV---GDRGPGG----AAGPKGDQGIAGSDGLP-----GDKGELGPSGLV 462
Query: 850 SPLPLEGSGAHQVLHNESKGSPTSAYPERKGSPTP-GFSTRRGSPTTGFIEQKGSPTSAY 908
P GS + TS G P P G G P G + G P
Sbjct: 463 GPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVP--GITGKPGVPGKEA 520
Query: 909 PERR---------GSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPM 959
E+R + + P+ P GS+ G AGP GP GP
Sbjct: 521 SEQRIRELCGGMISEQIAQLAAHLRKPLAP-----GSI-----GRPGPAGP--PGPPGP- 567
Query: 960 EVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESPRRLSLGQG-DSTEAATEERG 1018
GS+ P G R E G P P+ N Q + + + G G D E +G
Sbjct: 568 ----PGSIGHPGARGPPGYRGPTGELGDPGPRGN-QGDRGDKGAAGAGLDGPEGDQGPQG 622
Query: 1019 PR 1020
P+
Sbjct: 623 PQ 624
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 45.1 bits (105), Expect = 4e-04
Identities = 58/190 (30%), Positives = 70/190 (36%), Gaps = 14/190 (7%)
Query: 485 DPDDFTLGAGPRFP-ELGPDGHQRLDYVPSSASREVRHGS--DPAFAPGPRGLE----PS 537
DP L P P GP G+ L P G+ D F PGP+G+E PS
Sbjct: 989 DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGF-PGPQGVEGPPGPS 1047
Query: 538 GAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDGGD 597
G P + P Q + P + P G P+G GL + + G G D G
Sbjct: 1048 GVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG-PKGEPGLPGYPGNPGIKGSVG-DPGL 1105
Query: 598 DGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGP 657
GLP A+ PG P G P P P PGP GG P + GP
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGPPG---PKGISGPPGNPGLPGEPGPVGGGGHPGQPGP 1162
Query: 658 E-EPGLAKQD 666
E G QD
Sbjct: 1163 PGEKGKPGQD 1172
Score = 40.0 bits (92), Expect = 0.013
Identities = 56/189 (29%), Positives = 68/189 (35%), Gaps = 52/189 (27%)
Query: 495 PRFPEL----GPDGHQRLDYVPSSASREVRHG--SDPAFAPGPRGLE----PSGAPRPNL 544
P FP L GP G + P S G +P + PGP G++ P+G P P +
Sbjct: 137 PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY-PGPPGIQGLPGPTGIPGP-I 194
Query: 545 TQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDG-----GDDG 599
P PGP P GP+G GL G GE G G G
Sbjct: 195 GPPGPPGLMGPPGPPGLP--------GPKGNMGLN-------FQGPKGEKGEQGLQGPPG 239
Query: 600 LPA-------PMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGP 652
P P++ E + D PG R P G P R P PGP G G
Sbjct: 240 PPGQISEQKRPIDVEFQKGDQGLPGDRGPPG---PPGIRGP---------PGPPGGEKG- 286
Query: 653 EREGPEEPG 661
E+ EPG
Sbjct: 287 EKGEQGEPG 295
Score = 38.5 bits (88), Expect = 0.038
Identities = 57/184 (30%), Positives = 68/184 (36%), Gaps = 28/184 (15%)
Query: 494 GPRFPE--LGPDGHQRLDYVPSSASREVRHGSDPAFAPGPRGLE----PSGAPRPNLTQR 547
GP P+ GP G+ L P V G P PGP G + G P P +
Sbjct: 1128 GPPGPKGISGPPGNPGLPGEPGP----VGGGGHPG-QPGPPGEKGKPGQDGIPGPAGQKG 1182
Query: 548 FPCQAA-ARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDG-----GDDGLP 601
P Q PGP P G +G GL L G GE G G G P
Sbjct: 1183 EPGQPGFGNPGPPGLPGLS-----GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPP 1237
Query: 602 AP--MEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPG-PGSGGNGPEREGPE 658
P A E PG + P G P+ F+ P PG PG+GG E+ P
Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQ---GLPGPEGPPGLPGNGGIKGEKGNPG 1294
Query: 659 EPGL 662
+PGL
Sbjct: 1295 QPGL 1298
Score = 34.7 bits (78), Expect = 0.55
Identities = 39/141 (27%), Positives = 49/141 (34%), Gaps = 34/141 (24%)
Query: 868 KGSPTSAYPERKGSP-TPGFSTRRGSP-------TTGFIEQKGSPT-SAYPERRGSPVPP 918
KG P G P PG S ++G G KG P +P +G P PP
Sbjct: 1181 KGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPP 1240
Query: 919 VPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGE 978
SP P + E PK P +GP G R G + L P+G
Sbjct: 1241 -----GSPGPAL-------------EGPKGNPGPQGPPG-----RPGPTGFQGLPGPEGP 1277
Query: 979 RRMEDEGGFPVPQENGQPESP 999
+ GG + E G P P
Sbjct: 1278 PGLPGNGG--IKGEKGNPGQP 1296
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 45.1 bits (105), Expect = 4e-04
Identities = 58/190 (30%), Positives = 70/190 (36%), Gaps = 14/190 (7%)
Query: 485 DPDDFTLGAGPRFP-ELGPDGHQRLDYVPSSASREVRHGS--DPAFAPGPRGLE----PS 537
DP L P P GP G+ L P G+ D F PGP+G+E PS
Sbjct: 989 DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGF-PGPQGVEGPPGPS 1047
Query: 538 GAPRPNLTQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDGGD 597
G P + P Q + P + P G P+G GL + + G G D G
Sbjct: 1048 GVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG-PKGEPGLPGYPGNPGIKGSVG-DPGL 1105
Query: 598 DGLPAPMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGPEREGP 657
GLP A+ PG P G P P P PGP GG P + GP
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGPPG---PKGISGPPGNPGLPGEPGPVGGGGHPGQPGP 1162
Query: 658 E-EPGLAKQD 666
E G QD
Sbjct: 1163 PGEKGKPGQD 1172
Score = 40.0 bits (92), Expect = 0.013
Identities = 56/189 (29%), Positives = 68/189 (35%), Gaps = 52/189 (27%)
Query: 495 PRFPEL----GPDGHQRLDYVPSSASREVRHG--SDPAFAPGPRGLE----PSGAPRPNL 544
P FP L GP G + P S G +P + PGP G++ P+G P P +
Sbjct: 137 PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY-PGPPGIQGLPGPTGIPGP-I 194
Query: 545 TQRFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLASYLSGCHGEDG-----GDDG 599
P PGP P GP+G GL G GE G G G
Sbjct: 195 GPPGPPGLMGPPGPPGLP--------GPKGNMGLN-------FQGPKGEKGEQGLQGPPG 239
Query: 600 LPA-------PMEAEAYEDDVLAPGGRAPAGDLLPSAFRVPAAFPTKVPVPGPGSGGNGP 652
P P++ E + D PG R P G P R P PGP G G
Sbjct: 240 PPGQISEQKRPIDVEFQKGDQGLPGDRGPPG---PPGIRGP---------PGPPGGEKG- 286
Query: 653 EREGPEEPG 661
E+ EPG
Sbjct: 287 EKGEQGEPG 295
Score = 36.2 bits (82), Expect = 0.19
Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 53/175 (30%)
Query: 529 PGPRGLEPSGAP-RPNLT-------------QRFPCQAAARPGPDPAP-----EAEPERR 569
PGP+G+ SG P P L Q P +PG D P + EP +
Sbjct: 1130 PGPKGI--SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQP 1187
Query: 570 G----GPEGRAGLRRWRLASYLSGCHGEDG-----GDDGLPAPMEAEAYEDDVLAPGGRA 620
G GP G GL SG G+ G G+ GLP P + G
Sbjct: 1188 GFGNPGPPGLPGL---------SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG 1238
Query: 621 PAGDLLPSAFRVPAAFPTKVPVPG-------------PGSGGNGPEREGPEEPGL 662
P G P A P P PG PG+GG E+ P +PGL
Sbjct: 1239 PPGSPGP-ALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1292
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,893,001
Number of Sequences: 37866
Number of extensions: 3680662
Number of successful extensions: 17341
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 798
Number of HSP's that attempted gapping in prelim test: 14006
Number of HSP's gapped (non-prelim): 3634
length of query: 1179
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1066
effective length of database: 13,968,660
effective search space: 14890591560
effective search space used: 14890591560
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.