Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 156564378
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156564378 carcinoembryonic antigen-related cell adhesion
molecule 20 5L [Homo sapiens]
(596 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156564378 carcinoembryonic antigen-related cell adhesion mole... 1202 0.0
gi|156564393 carcinoembryonic antigen-related cell adhesion mole... 1167 0.0
gi|156564390 carcinoembryonic antigen-related cell adhesion mole... 695 0.0
gi|156564388 carcinoembryonic antigen-related cell adhesion mole... 695 0.0
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 202 5e-52
gi|68161541 carcinoembryonic antigen-related cell adhesion molec... 167 3e-41
gi|19923195 carcinoembryonic antigen-related cell adhesion molec... 167 3e-41
gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo sapi... 154 2e-37
gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1 [... 149 7e-36
gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo sapi... 149 7e-36
gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens] 148 2e-35
gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a [... 147 3e-35
gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b ... 145 8e-35
gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b [... 145 1e-34
gi|85861202 carcinoembryonic antigen-related cell adhesion molec... 144 2e-34
gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor ... 144 2e-34
gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [H... 141 2e-33
gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1... 128 2e-29
gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2... 126 5e-29
gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2... 126 5e-29
gi|40255013 carcinoembryonic antigen-related cell adhesion molec... 126 6e-29
gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c ... 123 4e-28
gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo sapi... 121 2e-27
gi|21314600 carcinoembryonic antigen-related cell adhesion molec... 117 3e-26
gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2 [... 116 5e-26
gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo sapi... 110 5e-24
gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo sapi... 110 5e-24
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 87 3e-17
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 87 3e-17
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 87 3e-17
>gi|156564378 carcinoembryonic antigen-related cell adhesion
molecule 20 5L [Homo sapiens]
Length = 596
Score = 1202 bits (3110), Expect = 0.0
Identities = 596/596 (100%), Positives = 596/596 (100%)
Query: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
Query: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMI 360
QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMI
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMI 360
Query: 361 STIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASN 420
STIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASN
Sbjct: 361 STIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASN 420
Query: 421 SLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRK 480
SLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRK
Sbjct: 421 SLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRK 480
Query: 481 TTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPEETYETKL 540
TTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPEETYETKL
Sbjct: 481 TTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPEETYETKL 540
Query: 541 PSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQINPSV 596
PSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQINPSV
Sbjct: 541 PSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQINPSV 596
>gi|156564393 carcinoembryonic antigen-related cell adhesion
molecule 20 5S [Homo sapiens]
Length = 584
Score = 1167 bits (3019), Expect = 0.0
Identities = 584/596 (97%), Positives = 584/596 (97%), Gaps = 12/596 (2%)
Query: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
Query: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMI 360
QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMI
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMI 360
Query: 361 STIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASN 420
STIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASN
Sbjct: 361 STIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASN 420
Query: 421 SLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRK 480
SLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRK
Sbjct: 421 SLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRK 480
Query: 481 TTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPEETYETKL 540
TTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVEL TKL
Sbjct: 481 TTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVEL------------TKL 528
Query: 541 PSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQINPSV 596
PSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQINPSV
Sbjct: 529 PSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQINPSV 584
>gi|156564390 carcinoembryonic antigen-related cell adhesion
molecule 20 4L [Homo sapiens]
Length = 503
Score = 695 bits (1794), Expect = 0.0
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
Query: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343
QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343
Score = 337 bits (865), Expect = 1e-92
Identities = 194/303 (64%), Positives = 208/303 (68%), Gaps = 15/303 (4%)
Query: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMIS 361
LS RT IH + R G Y C V N + S T+ + + ++
Sbjct: 208 LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLG---TLKVRVLETLTMPQVVPSSLN 264
Query: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST---GEHL-----GEQLIIRALTWEHDGI 413
+E + LT Q +S +W L EHL LII L G
Sbjct: 265 LVENARSVDLTCQTVNQS---VNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGP 321
Query: 414 YNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 473
Y C N ARS + + + PQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN
Sbjct: 322 YACEVWN-WGSRARSEPLELTINCPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 380
Query: 474 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPE 533
ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPE
Sbjct: 381 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPE 440
Query: 534 ETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN 593
ETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN
Sbjct: 441 ETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN 500
Query: 594 PSV 596
PSV
Sbjct: 501 PSV 503
Score = 102 bits (254), Expect = 1e-21
Identities = 59/184 (32%), Positives = 88/184 (47%)
Query: 253 LTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIH 312
L P + S +E V C T + ++ + W + ++ E +QLS D + L I
Sbjct: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
Query: 313 GLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT 372
+QR D+G Y CE + RS+P+ L + YGPD V I ES +E SS+T
Sbjct: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
Query: 373 LQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVL 432
+S P Y W L S H I A++ EH+G+Y C SNS T L+ ++
Sbjct: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246
Query: 433 VKVV 436
V+V+
Sbjct: 247 VRVL 250
>gi|156564388 carcinoembryonic antigen-related cell adhesion
molecule 20 4S [Homo sapiens]
Length = 491
Score = 695 bits (1794), Expect = 0.0
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
Query: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343
QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343
Score = 302 bits (774), Expect = 5e-82
Identities = 182/303 (60%), Positives = 196/303 (64%), Gaps = 27/303 (8%)
Query: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMIS 361
LS RT IH + R G Y C V N + S T+ + + ++
Sbjct: 208 LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLG---TLKVRVLETLTMPQVVPSSLN 264
Query: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST---GEHL-----GEQLIIRALTWEHDGI 413
+E + LT Q +S +W L EHL LII L G
Sbjct: 265 LVENARSVDLTCQTVNQS---VNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGP 321
Query: 414 YNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 473
Y C N ARS + + + PQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN
Sbjct: 322 YACEVWN-WGSRARSEPLELTINCPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 380
Query: 474 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPE 533
ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVEL
Sbjct: 381 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVEL-------- 432
Query: 534 ETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN 593
TKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN
Sbjct: 433 ----TKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN 488
Query: 594 PSV 596
PSV
Sbjct: 489 PSV 491
Score = 102 bits (254), Expect = 1e-21
Identities = 59/184 (32%), Positives = 88/184 (47%)
Query: 253 LTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIH 312
L P + S +E V C T + ++ + W + ++ E +QLS D + L I
Sbjct: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
Query: 313 GLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT 372
+QR D+G Y CE + RS+P+ L + YGPD V I ES +E SS+T
Sbjct: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
Query: 373 LQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVL 432
+S P Y W L S H I A++ EH+G+Y C SNS T L+ ++
Sbjct: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246
Query: 433 VKVV 436
V+V+
Sbjct: 247 VRVL 250
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 202 bits (515), Expect = 5e-52
Identities = 131/398 (32%), Positives = 193/398 (48%), Gaps = 19/398 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KP I + +E +D V C + N T W NN S+ R+QLS D + LT+
Sbjct: 321 EPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTL 380
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
L V R D G Y+C ++ L SDP+ L+V YGPD I S G ++
Sbjct: 381 LSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTI-------SPSYTYYRPGVNL 433
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ S+PP Y+W + +I HT F I ++ ++ GLY C +NSA+ S
Sbjct: 434 SLSCHAASNPPAQYSWLIDGNIQQHTQELF-ISNITEKNSGLYTCQANNSASGHSRTTVK 492
Query: 246 KVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSAD 305
+ V L P + ++ VE+ +V TC+ Q+ W+++GQ L S LQLS
Sbjct: 493 TITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNG 552
Query: 306 NRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEA 365
NRTL + + RND Y C + N S RS+P+ L + YGPD I+ +S +
Sbjct: 553 NRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYL------ 606
Query: 366 ELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGL 425
++L L C + S P +Y W + +H + L I +T ++G Y C SN TG
Sbjct: 607 -SGANLNLSCHSASNPSPQYSWRINGIPQQHT-QVLFIAKITPNNNGTYACFVSNLATGR 664
Query: 426 ARS--TSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAV 461
S S+ V G S LS+GA GI+IG+L +A+
Sbjct: 665 NNSIVKSITVSASG-TSPGLSAGATVGIMIGVLVGVAL 701
Score = 200 bits (508), Expect = 4e-51
Identities = 122/371 (32%), Positives = 190/371 (51%), Gaps = 18/371 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
EL KPSI+ + +E KD V F C + + T W NN S+ R+QLS + LT+
Sbjct: 143 ELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTL 202
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPD-PVEIKLESGVASGEVVEVMEGSS 184
V R D+ +Y+CE ++ + ++RSD + L+V YGPD P L + SGE +
Sbjct: 203 FNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGE--------N 254
Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGT 244
+ S+PP Y+WF+ + +T+ I ++ + G Y C NS T L+
Sbjct: 255 LNLSCHAASNPPAQYSWFV-NGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTV 313
Query: 245 LKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSA 304
+ V P + ++ N VE+ +V LTC+ Q+ W+++ Q L S LQLS
Sbjct: 314 TTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSN 373
Query: 305 DNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIE 364
DNRTL + + RND GPY C + N S S+P+ L + YGPD I+ S
Sbjct: 374 DNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISP-------SYTY 426
Query: 365 AELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTG 424
+L+L C A S P A+Y W ++ + +H ++L I +T ++ G+Y C A+NS +G
Sbjct: 427 YRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHT-QELFISNITEKNSGLYTCQANNSASG 485
Query: 425 LARSTSVLVKV 435
+R+T + V
Sbjct: 486 HSRTTVKTITV 496
Score = 108 bits (270), Expect = 1e-23
Identities = 74/233 (31%), Positives = 111/233 (47%), Gaps = 22/233 (9%)
Query: 203 LLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSS 262
L+ +I+ + T +T+H + + LV+ AT + RV L P + ++
Sbjct: 108 LIQNIIQNDTGFYTLHVIKSD-------LVNEEATG-------QFRVYPELPKPSISSNN 153
Query: 263 LNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPY 322
VE+ +V TC+ Q W+++ Q L S LQLS NRTL + + RNDT Y
Sbjct: 154 SKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASY 213
Query: 323 ACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPG 382
CE N S RS+ + L + YGPD I+ + S +L L C A S P
Sbjct: 214 KCETQNPVSARRSDSVILNVLYGPDAPTISPLNTS-------YRSGENLNLSCHAASNPP 266
Query: 383 AEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
A+Y W + + T + ++L I +T + G Y C A NS TGL R+T + V
Sbjct: 267 AQYSWFV-NGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITV 318
Score = 98.2 bits (243), Expect = 2e-20
Identities = 77/276 (27%), Positives = 121/276 (43%), Gaps = 29/276 (10%)
Query: 2 GPAD-----SWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQS--------EDVV 48
GP D S+ ++ G+ LS S +PPA ++ N TQ ++
Sbjct: 414 GPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSG 473
Query: 49 LPVFGTPRTPQIHGR--------SRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIH 100
L + H R S EL KPSI+ + +E KD V F C + N T
Sbjct: 474 LYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYL 533
Query: 101 WVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGP 160
W N S+ R+QLS + LT+ V R D+ Y C ++++ + RSDP+ LDV YGP
Sbjct: 534 WWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGP 593
Query: 161 DPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAV 220
D + + S + G+++ + S+P Y+W ++ I T+ I +
Sbjct: 594 D-------TPIISPPDSSYLSGANLNLSCHSASNPSPQYSW-RINGIPQQHTQVLFIAKI 645
Query: 221 SREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMP 256
+ + G Y C VSN AT ++ + V + T P
Sbjct: 646 TPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSP 681
Score = 67.0 bits (162), Expect = 5e-11
Identities = 92/460 (20%), Positives = 174/460 (37%), Gaps = 63/460 (13%)
Query: 3 PADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHG 62
P W W +LL+ASL T W+PP A+LT+ + P + + ++V+L V P+ + G
Sbjct: 7 PPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ--HLFG 64
Query: 63 RSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKI 122
S G ++ + Y I + R + + +
Sbjct: 65 YS---------WYKGERVDGNRQIIGY--------VIGTQQATPGPAYSGREIIYPNASL 107
Query: 123 LTILIVQREDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVME 181
L I+Q D+G Y + L+++ + F P P ++S V +
Sbjct: 108 LIQNIIQ-NDTGFYTLHVIKSDLVNEEATGQFRVYPELPKP-------SISSNNSKPVED 159
Query: 182 GSSMTFLAETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSN 234
++ F E ++ W S+ LS+ RT T+ V+R Y+C N
Sbjct: 160 KDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQN 219
Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQP 293
+ S ++ + VL P + P + + + +++L+C N WF++G
Sbjct: 220 PVSARRS-DSVILNVLYGPDAPTISPLNTS-YRSGENLNLSCHAASNPPAQYSWFVNG-- 275
Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRA-RSEPLELTINYGPDQVHIT 352
+ L I + N++G Y C+ N + R+ +T+ P + IT
Sbjct: 276 -------TFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFIT 328
Query: 353 RESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHST--------GEHLGEQLIIR 404
+++ + E ++ L C E + Y W + + + + L +
Sbjct: 329 SNNSNPV------EDEDAVALTCEPEIQ-NTTYLWWVNNQSLPVSPRLQLSNDNRTLTLL 381
Query: 405 ALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLS 444
++T G Y C N L+ +L + GP ++S
Sbjct: 382 SVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTIS 421
Score = 41.6 bits (96), Expect = 0.002
Identities = 90/438 (20%), Positives = 158/438 (36%), Gaps = 74/438 (16%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A +S+ V+L V P P +SP + T Y + +++N
Sbjct: 219 NPVSARRSDSVILNVLYGPDAP--------------TISP--------LNTSYRSGENLN 256
Query: 97 ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
++ H SN S + Q S + + V +SG+Y C+A ++ +
Sbjct: 257 LSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITV--NNSGSYTCQAHNSDTGLNRTTVT 314
Query: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI------ 207
Y P + + VE + ++T E ++ Y W++ +
Sbjct: 315 TITVYAEPPKPFITSN---NSNPVEDEDAVALTCEPEIQN---TTYLWWVNNQSLPVSPR 368
Query: 208 --LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNL 265
LS+ RT T+ +V+R G Y C + N + + + + VL P + P S
Sbjct: 369 LQLSNDNRTLTLLSVTRNDVGPYECGIQNKLS-VDHSDPVILNVLYGPDDPTISP-SYTY 426
Query: 266 VENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYAC 324
++ L+C N W + G + + L I + ++G Y C
Sbjct: 427 YRPGVNLSLSCHAASNPPAQYSWLIDG---------NIQQHTQELFISNITEKNSGLYTC 477
Query: 325 EVWNWGS-RARSEPLELTINYGPDQVHITR------ESASEMISTIEAELNSSLTLQCWA 377
+ N S +R+ +T++ + I+ E + T E E + T W
Sbjct: 478 QANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQN--TTYLWW 535
Query: 378 ESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV-- 435
+ L+ S G L + +T Y C NS++ RS V + V
Sbjct: 536 VNGQSLPVSPRLQLSNG---NRTLTLFNVTRNDARAYVCGIQNSVSA-NRSDPVTLDVLY 591
Query: 436 ------VGPQSSSLSSGA 447
+ P SS SGA
Sbjct: 592 GPDTPIISPPDSSYLSGA 609
>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 2 precursor [Homo sapiens]
Length = 464
Score = 167 bits (422), Expect = 3e-41
Identities = 95/282 (33%), Positives = 149/282 (52%), Gaps = 11/282 (3%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
EL KPSI+ + +E KD V F C + + T W NN S+ R+QLS + LT+
Sbjct: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTL 202
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
L V R D+G Y+CE ++ + + RSDP+ L+V YGPD I S G+++
Sbjct: 203 LSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTI-------SPSDTYYRPGANL 255
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ S+PP Y+W L++ +T+ I ++ + G Y C +NS T +
Sbjct: 256 SLSCYAASNPPAQYSW-LINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVK 314
Query: 246 KVRVLE---TLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQL 302
+ V E + PQ+ S + + SV+LTC T + ++++WF Q L SE ++L
Sbjct: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKL 374
Query: 303 SADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINY 344
S N TL I+ ++R D G Y CEV+N S+ +S+P+ L +NY
Sbjct: 375 SQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY 416
Score = 117 bits (294), Expect = 2e-26
Identities = 76/224 (33%), Positives = 115/224 (51%), Gaps = 11/224 (4%)
Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC 276
I V++ G Y V S ++ T + V L P + ++ N VE+ +V TC
Sbjct: 109 IQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTC 167
Query: 277 QTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
+ Q W+++ Q L S LQLS NRTL + + RNDTGPY CE+ N S RS+
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSD 227
Query: 337 PLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEH 396
P+ L + YGPD I+ S ++L+L C+A S P A+Y W L + T +
Sbjct: 228 PVTLNVTYGPDTPTISP-------SDTYYRPGANLSLSCYAASNPPAQYSW-LINGTFQQ 279
Query: 397 LGEQLIIRALTWEHDGIYNCTASNSLTGLARST--SVLVKVVGP 438
++L I +T + G Y C A+NS+TG R+T +++V + P
Sbjct: 280 STQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSP 323
Score = 86.3 bits (212), Expect = 7e-17
Identities = 50/127 (39%), Positives = 68/127 (53%)
Query: 54 TPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHER 113
T +T + S +AKP I S T KD V C+T D I+I W N S+ ER
Sbjct: 312 TVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSER 371
Query: 114 MQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVAS 173
M+LS+ L+I V+RED+GTY CE + + +SDPI L+V Y P E L G +
Sbjct: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIA 431
Query: 174 GEVVEVM 180
G V+ V+
Sbjct: 432 GIVIGVV 438
Score = 84.7 bits (208), Expect = 2e-16
Identities = 111/481 (23%), Positives = 190/481 (39%), Gaps = 63/481 (13%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL T W+PP AQLT + P + + ++V+L V P+ Q+ G S +
Sbjct: 15 WQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ--QLFGYSWYKGE- 71
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
V I + T T N + N S++ V +
Sbjct: 72 --RVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQN---------------VTQ 114
Query: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
D+G Y + + L+++ + F P P ++S V + ++ F
Sbjct: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167
Query: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
E ++ W S+ LS+ RT T+ +V+R G Y C + N + S
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRS- 226
Query: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
+ + V P + PS A ++ L+C N W ++G
Sbjct: 227 DPVTLNVTYGPDTPTISPSDTYYRPGA-NLSLSCYAASNPPAQYSWLINGT--------- 276
Query: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMIS 361
+ L I + N++G Y C N + ++ I V + + +
Sbjct: 277 FQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPV-VAKPQIKASKT 335
Query: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST---GEHL-----GEQLIIRALTWEHDGI 413
T+ + S+ L C + + G RW ++ + E + L I + E G
Sbjct: 336 TVTGD-KDSVNLTC-STNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGT 393
Query: 414 YNCTASNSLTGLARSTSVLVKV---VGPQSSSLSSGAIAGIVIGILAVIA-VASELGYFL 469
Y C N ++ +S +++ V PQ + LS GAIAGIVIG++A++A +A L FL
Sbjct: 394 YWCEVFNPISK-NQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALIAVALACFL 452
Query: 470 Y 470
+
Sbjct: 453 H 453
>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 1 precursor [Homo sapiens]
Length = 526
Score = 167 bits (422), Expect = 3e-41
Identities = 95/282 (33%), Positives = 149/282 (52%), Gaps = 11/282 (3%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
EL KPSI+ + +E KD V F C + + T W NN S+ R+QLS + LT+
Sbjct: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTL 202
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
L V R D+G Y+CE ++ + + RSDP+ L+V YGPD I S G+++
Sbjct: 203 LSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTI-------SPSDTYYRPGANL 255
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ S+PP Y+W L++ +T+ I ++ + G Y C +NS T +
Sbjct: 256 SLSCYAASNPPAQYSW-LINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVK 314
Query: 246 KVRVLE---TLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQL 302
+ V E + PQ+ S + + SV+LTC T + ++++WF Q L SE ++L
Sbjct: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKL 374
Query: 303 SADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINY 344
S N TL I+ ++R D G Y CEV+N S+ +S+P+ L +NY
Sbjct: 375 SQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY 416
Score = 117 bits (294), Expect = 2e-26
Identities = 76/224 (33%), Positives = 115/224 (51%), Gaps = 11/224 (4%)
Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC 276
I V++ G Y V S ++ T + V L P + ++ N VE+ +V TC
Sbjct: 109 IQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTC 167
Query: 277 QTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
+ Q W+++ Q L S LQLS NRTL + + RNDTGPY CE+ N S RS+
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSD 227
Query: 337 PLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEH 396
P+ L + YGPD I+ S ++L+L C+A S P A+Y W L + T +
Sbjct: 228 PVTLNVTYGPDTPTISP-------SDTYYRPGANLSLSCYAASNPPAQYSW-LINGTFQQ 279
Query: 397 LGEQLIIRALTWEHDGIYNCTASNSLTGLARST--SVLVKVVGP 438
++L I +T + G Y C A+NS+TG R+T +++V + P
Sbjct: 280 STQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSP 323
Score = 90.9 bits (224), Expect = 3e-18
Identities = 121/528 (22%), Positives = 208/528 (39%), Gaps = 68/528 (12%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL T W+PP AQLT + P + + ++V+L V P+ Q+ G S +
Sbjct: 15 WQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ--QLFGYSWYKGE- 71
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
V I + T T N + N S++ V +
Sbjct: 72 --RVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQN---------------VTQ 114
Query: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
D+G Y + + L+++ + F P P ++S V + ++ F
Sbjct: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167
Query: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
E ++ W S+ LS+ RT T+ +V+R G Y C + N + S
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRS- 226
Query: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
+ + V P + PS A ++ L+C N W ++G
Sbjct: 227 DPVTLNVTYGPDTPTISPSDTYYRPGA-NLSLSCYAASNPPAQYSWLINGT--------- 276
Query: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMIS 361
+ L I + N++G Y C N + ++ I V + + +
Sbjct: 277 FQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPV-VAKPQIKASKT 335
Query: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST---GEHL-----GEQLIIRALTWEHDGI 413
T+ + S+ L C + + G RW ++ + E + L I + E G
Sbjct: 336 TVTGD-KDSVNLTC-STNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGT 393
Query: 414 YNCTASNSLTGLARSTSVLVKV---VGPQSSSLSSGAIAGIVIGILAVIA-VASELGYFL 469
Y C N ++ +S +++ V PQ + LS GAIAGIVIG++A++A +A L FL
Sbjct: 394 YWCEVFNPISK-NQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALIAVALACFL 452
Query: 470 YIRNARRPS--RKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNIS 515
+ R S R TE H+ S ++H +P ++ Y ++
Sbjct: 453 HFGKTGRASDQRDLTE---HKPSVSNHTQDHSNDPPNKMNEVTYSTLN 497
>gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo
sapiens]
Length = 426
Score = 154 bits (390), Expect = 2e-37
Identities = 118/445 (26%), Positives = 196/445 (44%), Gaps = 48/445 (10%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+PP A++T+ A P ++ +DV+L V P+
Sbjct: 15 WKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQN------------- 61
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVF---HERMQLSKDGKILTILI 127
PG + +M Y + I ++ + +++ + + L I
Sbjct: 62 ----LPGYFWYKGEMTDLY------HYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQN 111
Query: 128 VQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTF 187
V R+D+GTY + +R D ++++ + ++ S + E
Sbjct: 112 VTRKDAGTYTLH-----IIKRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAMEAVR 166
Query: 188 LAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
L +Y W++ L S T RT + V++ G Y C + N +
Sbjct: 167 LICDPETLDASYLWWMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVS-A 225
Query: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEH 299
S + + +L L +P + ++LN EN + TC+ +++ W+L+GQ L S
Sbjct: 226 SRSDPVTLNLLPKLPIPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPG 285
Query: 300 LQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEM 359
++ +NR LI+ + RN+TGPY CE+ + RS P+ L + YGPD I
Sbjct: 286 VKRPIENRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNVLYGPDLPRI-------Y 338
Query: 360 ISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTAS 419
S +L L C+ ES P AEY WT+ + + G++L I +T H G+Y C+
Sbjct: 339 PSFTYYRSGENLDLSCFTESNPPAEYFWTI-NGKFQQSGQKLFIPQITRNHSGLYACSVH 397
Query: 420 NSLTGLARSTSVLVKVVGPQSSSLS 444
NS TG S S+ VKV GP L+
Sbjct: 398 NSATGKEISKSMTVKVSGPCHGDLT 422
>gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1
[Homo sapiens]
Length = 419
Score = 149 bits (376), Expect = 7e-36
Identities = 119/436 (27%), Positives = 195/436 (44%), Gaps = 48/436 (11%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+PP AQ+T+ A P ++ +DV+L V P+ +
Sbjct: 15 WKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLAGY--------- 65
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSV---VFHERMQLSKDGKILTILI 127
I K +T+ IT + V + + R ++ + +L I
Sbjct: 66 ---------IWYKGQMTYLYHY----ITSYVVDGQRIIYGPAYSGRERVYSNASLL-IQN 111
Query: 128 VQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTF 187
V +ED+G+Y + +R D + + ++ S + E
Sbjct: 112 VTQEDAGSYTLH-----IIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVI 166
Query: 188 LAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
L + P +Y W++ L S T RT I V++ G Y C + N +
Sbjct: 167 LTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVS-A 225
Query: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEH 299
S + + +L L+ P + ++LN EN + TC+ +++ W+L+GQ L S
Sbjct: 226 SRSDPVTLNLLPKLSKPYITINNLNPRENKDVLTFTCEPKSKNYTYIWWLNGQSLPVSPR 285
Query: 300 LQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEM 359
++ +NR LI+ + RN+TGPY CE+ + RS+P+ L + YGPD I
Sbjct: 286 VKRPIENRILILPNVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPSI-------Y 338
Query: 360 ISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTAS 419
S +L L C+AES P A+Y WT+ + + G++L I +T +H G+Y C+
Sbjct: 339 PSFTYYRSGENLYLSCFAESNPRAQYSWTI-NGKFQLSGQKLSIPQITTKHSGLYACSVR 397
Query: 420 NSLTGLARSTSVLVKV 435
NS TG S S+ VKV
Sbjct: 398 NSATGKESSKSITVKV 413
>gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo
sapiens]
Length = 428
Score = 149 bits (376), Expect = 7e-36
Identities = 124/447 (27%), Positives = 200/447 (44%), Gaps = 58/447 (12%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+A L W+ P AQ+T+ A P ++ +DV+L V P+
Sbjct: 15 WKGLLLTALLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQ-------------- 60
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSV---VFHERMQLSKDGKILTILI 127
++A + KD+ + IT + V + + + R + + +L I
Sbjct: 61 NLAGYIWYKGQMKDLYHY--------ITSYVVDGQIIIYGPAYSGRETVYSNASLL-IQN 111
Query: 128 VQREDSGTYQC---EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--EVMEG 182
V RED+G+Y + D + F P P ++S + E ME
Sbjct: 112 VTREDAGSYTLHIVKRGDGTRGETGHFTFTLYLETPKP-------SISSSNLYPREDMEA 164
Query: 183 SSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSN 234
S+T ET P +Y W++ L S RT + V++ G Y C + N
Sbjct: 165 VSLTCDPET---PDASYLWWMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRN 221
Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPL 294
+ S + + +L L P + ++LN EN + TC+ +++ W+L+GQ L
Sbjct: 222 PVS-ASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSL 280
Query: 295 LPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRE 354
S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L + YGPD I
Sbjct: 281 PVSPRVKRPIENRILILPSVTRNETGPYQCEIQDRYGGIRSYPVTLNVLYGPDLPRI--- 337
Query: 355 SASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIY 414
S +L L C+A+S P AEY WT+ + + G++L I +T +H G+Y
Sbjct: 338 ----YPSFTYYHSGENLYLSCFADSNPPAEYSWTI-NGKFQLSGQKLFIPQITTKHSGLY 392
Query: 415 NCTASNSLTGLARSTSVLVKVVGPQSS 441
C+ NS TG+ S S+ VKV P +
Sbjct: 393 ACSVRNSATGMESSKSMTVKVSAPSGT 419
>gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]
Length = 426
Score = 148 bits (373), Expect = 2e-35
Identities = 125/447 (27%), Positives = 201/447 (44%), Gaps = 66/447 (14%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
W G+LL+ASL W+ P AQ+T+ A P ++ +DV+L V P+ + G+ R+
Sbjct: 15 WKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L +T Y D I I+ + + + + L I
Sbjct: 75 LYH---------------YITSYVV--DGEIIIYGPA-------YSGRETAYSNASLLIQ 110
Query: 127 IVQREDSGTYQC------EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--E 178
V RED+G+Y + + + + + L+ P P ++S + E
Sbjct: 111 NVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLET---PKP-------SISSSNLNPRE 160
Query: 179 VMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRC 230
ME S+T ET P +Y W++ L S T RT + V++ G Y C
Sbjct: 161 TMEAVSLTCDPET---PDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYEC 217
Query: 231 LVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLS 290
+ N + S + + +L L P + ++LN EN ++ TC+ +++ W+L+
Sbjct: 218 EIRNPVS-ASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLN 276
Query: 291 GQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVH 350
GQ L S ++ +NR LI+ + RN+TGPY CE+ + RS+P+ L + YGPD
Sbjct: 277 GQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPR 336
Query: 351 ITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEH 410
I S L L C A+S P A+Y WT+ + G++L IR +T +H
Sbjct: 337 I-------YPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKF-QLPGQKLFIRHITTKH 388
Query: 411 DGIYNCTASNSLTGLARSTSVLVKVVG 437
G+Y C+ NS TG S S+ V+V G
Sbjct: 389 SGLYVCSVRNSATGKESSKSMTVEVSG 415
Score = 67.4 bits (163), Expect = 4e-11
Identities = 64/247 (25%), Positives = 101/247 (40%), Gaps = 32/247 (12%)
Query: 209 SHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTM------PQVVPSS 262
+++ + I V+RE G Y + GT V T T+ P + S+
Sbjct: 101 AYSNASLLIQNVTREDAGSYTLHIIKGDD-----GTRGVTGRFTFTLHLETPKPSISSSN 155
Query: 263 LNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPY 322
LN E +V LTC + W+++GQ L + L+LS NRTL + G+ + GPY
Sbjct: 156 LNPRETMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPY 215
Query: 323 ACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPG 382
CE+ N S +RS+P+ L + + +IT + + E L C +S+
Sbjct: 216 ECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLN------PRENKDVLNFTCEPKSE-N 268
Query: 383 AEYRWTLEHSTGEHL-----------GEQLIIRALTWEHDGIYNCTASNSLTGLARSTSV 431
Y W L G+ L LI+ ++T G Y C + G+
Sbjct: 269 YTYIWWL---NGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVT 325
Query: 432 LVKVVGP 438
L + GP
Sbjct: 326 LNVLYGP 332
>gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a
[Homo sapiens]
Length = 426
Score = 147 bits (371), Expect = 3e-35
Identities = 125/447 (27%), Positives = 201/447 (44%), Gaps = 66/447 (14%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
W G+LL+ASL W+PP AQ+T+ A P ++ +DV+L V P+ + G+ R+
Sbjct: 15 WKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L +T Y D I I+ + R + + +L I
Sbjct: 75 LYH---------------YITSYVV--DGQIIIY------GPAYSGRETIYSNASLL-IQ 110
Query: 127 IVQREDSGTYQC------EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--E 178
V +ED+G+Y + + + ++L+ P P ++S ++ E
Sbjct: 111 NVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLET---PKP-------SISSSKLNPRE 160
Query: 179 VMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRC 230
ME S+T ET P +Y W++ L S T RT + V++ G Y C
Sbjct: 161 AMEAVSLTCDPET---PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYEC 217
Query: 231 LVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLS 290
+ N + S + +L L P + ++L EN ++ TC+ +++ W+L+
Sbjct: 218 EIRNPVS-ASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLN 276
Query: 291 GQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVH 350
GQ L S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L + YGPD
Sbjct: 277 GQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPR 336
Query: 351 ITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEH 410
I S L L C A+S P A+Y WT+ + + G++L I +T +H
Sbjct: 337 I-------YPSFTYYRSGEVLYLSCSADSNPPAQYSWTI-NGKFQLSGQKLFIPQITTKH 388
Query: 411 DGIYNCTASNSLTGLARSTSVLVKVVG 437
G+Y C+ NS TG S S+ VKV G
Sbjct: 389 SGLYACSVRNSATGKESSKSMTVKVSG 415
Score = 68.2 bits (165), Expect = 2e-11
Identities = 62/242 (25%), Positives = 98/242 (40%), Gaps = 24/242 (9%)
Query: 210 HTTRTFTIHAVSREHEGLYRC-LVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268
++ + I V++E G Y ++ + G + P + S LN E
Sbjct: 102 YSNASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREA 161
Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
+V LTC + W+++GQ L S LQLS NRTL + G+ + GPY CE+ N
Sbjct: 162 MEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRN 221
Query: 329 WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSS-LTLQCWAESKPGAEYRW 387
S +RS+P L + + +IT I+ ++ N L C +S+ Y W
Sbjct: 222 PVSASRSDPFTLNLLPKLPKPYIT-------INNLKPRENKDVLNFTCEPKSE-NYTYIW 273
Query: 388 TLEHSTGEHL-----------GEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVV 436
L G+ L LI+ ++T G Y C + G+ L +
Sbjct: 274 WL---NGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLY 330
Query: 437 GP 438
GP
Sbjct: 331 GP 332
>gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b
[Homo sapiens]
Length = 419
Score = 145 bits (367), Expect = 8e-35
Identities = 124/445 (27%), Positives = 200/445 (44%), Gaps = 66/445 (14%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
W G+LL+ASL W+PP AQ+T+ A P ++ +DV+L V P+ + G+ R+
Sbjct: 15 WKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L +T Y D I I+ + R + + +L I
Sbjct: 75 LYH---------------YITSYVV--DGQIIIY------GPAYSGRETIYSNASLL-IQ 110
Query: 127 IVQREDSGTYQC------EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--E 178
V +ED+G+Y + + + ++L+ P P ++S ++ E
Sbjct: 111 NVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLET---PKP-------SISSSKLNPRE 160
Query: 179 VMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRC 230
ME S+T ET P +Y W++ L S T RT + V++ G Y C
Sbjct: 161 AMEAVSLTCDPET---PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYEC 217
Query: 231 LVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLS 290
+ N + S + +L L P + ++L EN ++ TC+ +++ W+L+
Sbjct: 218 EIRNPVS-ASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLN 276
Query: 291 GQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVH 350
GQ L S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L + YGPD
Sbjct: 277 GQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPR 336
Query: 351 ITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEH 410
I S L L C A+S P A+Y WT+ + + G++L I +T +H
Sbjct: 337 I-------YPSFTYYRSGEVLYLSCSADSNPPAQYSWTI-NGKFQLSGQKLFIPQITTKH 388
Query: 411 DGIYNCTASNSLTGLARSTSVLVKV 435
G+Y C+ NS TG S S+ VKV
Sbjct: 389 SGLYACSVRNSATGKESSKSMTVKV 413
Score = 68.2 bits (165), Expect = 2e-11
Identities = 62/242 (25%), Positives = 98/242 (40%), Gaps = 24/242 (9%)
Query: 210 HTTRTFTIHAVSREHEGLYRC-LVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268
++ + I V++E G Y ++ + G + P + S LN E
Sbjct: 102 YSNASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREA 161
Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
+V LTC + W+++GQ L S LQLS NRTL + G+ + GPY CE+ N
Sbjct: 162 MEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRN 221
Query: 329 WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSS-LTLQCWAESKPGAEYRW 387
S +RS+P L + + +IT I+ ++ N L C +S+ Y W
Sbjct: 222 PVSASRSDPFTLNLLPKLPKPYIT-------INNLKPRENKDVLNFTCEPKSE-NYTYIW 273
Query: 388 TLEHSTGEHL-----------GEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVV 436
L G+ L LI+ ++T G Y C + G+ L +
Sbjct: 274 WL---NGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLY 330
Query: 437 GP 438
GP
Sbjct: 331 GP 332
>gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b
[Homo sapiens]
Length = 424
Score = 145 bits (366), Expect = 1e-34
Identities = 125/445 (28%), Positives = 194/445 (43%), Gaps = 61/445 (13%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+ P AQ+ + A P ++ +DV+L V P+ +
Sbjct: 15 WKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGY--------- 65
Query: 71 SIAVSPGTAIEQKDMVT---FYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILI 127
I K +T Y T+ V+ I + + R + + +L I
Sbjct: 66 ---------IWYKGQMTDLYHYITSYVVHGQIIY-----GPAYSGRETVYSNASLL-IQN 110
Query: 128 VQREDSGTYQCEARDALLSQRSDPI------FLDVKYGPDPVEIKLESGVASGEVVEVME 181
V +ED+G+Y + +R D F Y P S + EV+E +
Sbjct: 111 VTQEDAGSYTLH-----IIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVR 165
Query: 182 GSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVS 233
L P +Y W L L S T RT + V++ G Y C +
Sbjct: 166 ------LICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIR 219
Query: 234 NSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQP 293
N + S + + +L L MP + ++LN E + TC+ +++ W+L+GQ
Sbjct: 220 NPVS-ASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQS 278
Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITR 353
L S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L + YGPD I
Sbjct: 279 LPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRI-- 336
Query: 354 ESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGI 413
S +L L C+A+S P AEY WT+ + + G++L I +T H G+
Sbjct: 337 -----YPSFTYYRSGENLDLSCFADSNPPAEYSWTI-NGKFQLSGQKLFIPQITTNHSGL 390
Query: 414 YNCTASNSLTGLARSTSVLVKVVGP 438
Y C+ NS TG S S++VKV GP
Sbjct: 391 YACSVRNSATGKEISKSMIVKVSGP 415
>gi|85861202 carcinoembryonic antigen-related cell adhesion molecule
16 [Homo sapiens]
Length = 484
Score = 144 bits (364), Expect = 2e-34
Identities = 106/350 (30%), Positives = 167/350 (47%), Gaps = 47/350 (13%)
Query: 175 EVVEVMEGSSMTFLAETKSHPPCAYTWF---------LLDSIL----------SHTTR-- 213
E + EG ++T + S AY+W+ L+ S + +HT R
Sbjct: 86 EPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREA 145
Query: 214 -----TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268
+ I + H G Y N + +G V+V E L P V+ +S LVE
Sbjct: 146 VRPDGSLDIQGILPRHSGTYILQTFNRQLQ-TEVGYGHVQVHEILAQPTVLANSTALVER 204
Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
++ L C + + + V+WF +G L + L LS D R L HG++R + G Y CEVWN
Sbjct: 205 RDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWN 264
Query: 329 WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWT 388
S +RSEP+ LT+ +GP++V I ++S + TI+ + N+SLTL C + S P EY WT
Sbjct: 265 PVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWT 324
Query: 389 LEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAI 448
++ + L I ++T +G Y C A N+ T L+ S SV+VK LS+ A+
Sbjct: 325 FNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVK--------LSAAAV 376
Query: 449 AGIVIGI-----------LAVIAVASELGYFLYIRN-ARRPSRKTTEDPS 486
A +++ + L V +L + + R A P+R ++ PS
Sbjct: 377 ATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPS 426
Score = 105 bits (262), Expect = 1e-22
Identities = 73/297 (24%), Positives = 133/297 (44%), Gaps = 20/297 (6%)
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
LA+P++ + +E++D + C++ + W N ++ R+ LS DG++L
Sbjct: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248
Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
++RE++G YQCE + + RS+PI L V +GP+ V I +S +G ++V +S+T
Sbjct: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLT 308
Query: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246
++S P Y W L + I +++ EG Y C+ N+ T LS ++
Sbjct: 309 LWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVV 368
Query: 247 VRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL------ 300
V++ +VP E + V LT Q + + V + G P+ L
Sbjct: 369 VKLSAAAVATMIVPVPTKPTE-GQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSG 427
Query: 301 -----------QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGP 346
++ N +L++ L DTG Y + + ++E LE+ + P
Sbjct: 428 TWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVT--VQGKTETLEVELQVAP 482
>gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor
[Homo sapiens]
Length = 419
Score = 144 bits (363), Expect = 2e-34
Identities = 121/438 (27%), Positives = 193/438 (44%), Gaps = 52/438 (11%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
W G+LL+ASL W+PP AQ+T+ A P ++ +DV+L V P+ + G+ R+
Sbjct: 15 WKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L T+ + Y T++ +N S++ Q +D T+
Sbjct: 75 LYHYV------TSYIVDGQIIKYGPAYSGRETVY---SNASLLIQNVTQ--EDTGSYTLH 123
Query: 127 IVQRED-SGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
I++R D +G L + P + P E E +
Sbjct: 124 IIKRGDGTGGVTGRFTFTLYLETPKPSISSSNFNPR----------------EATEAVIL 167
Query: 186 TFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSNSAT 237
T ET P +Y W++ L S T RT + V+ G Y C + N +
Sbjct: 168 TCDPET---PDASYLWWMNGQSLPMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNPVS 224
Query: 238 HLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPS 297
S + + +L L P + ++LN EN TC+ +++ W+L+GQ L S
Sbjct: 225 -ASRSDPVTLNLLPKLPKPYITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVS 283
Query: 298 EHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESAS 357
++ +NR LI+ + RN+TGPY CE+ + RS+P+ L + YGPD I
Sbjct: 284 PRVKRRIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRI------ 337
Query: 358 EMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCT 417
S +L L C+A+S P A+Y WT+ + + G++L I +T +H G+Y C+
Sbjct: 338 -YPSFTYYHSGQNLYLSCFADSNPPAQYSWTI-NGKFQLSGQKLSIPQITTKHSGLYACS 395
Query: 418 ASNSLTGLARSTSVLVKV 435
NS TG S SV V+V
Sbjct: 396 VRNSATGKESSKSVTVRV 413
Score = 67.0 bits (162), Expect = 5e-11
Identities = 63/244 (25%), Positives = 101/244 (41%), Gaps = 27/244 (11%)
Query: 203 LLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSS 262
L+ ++ T ++T+H + R G V+ T L T K P + S+
Sbjct: 108 LIQNVTQEDTGSYTLHIIKR---GDGTGGVTGRFTFTLYLETPK---------PSISSSN 155
Query: 263 LNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPY 322
N E +V LTC + W+++GQ L + LQLS NRTL + G+ GPY
Sbjct: 156 FNPREATEAVILTCDPETPDASYLWWMNGQSLPMTHSLQLSETNRTLYLFGVTNYTAGPY 215
Query: 323 ACEVWNWGSRARSEPLELTINYGPDQVHIT----RESASEMISTIEAELNSSLTLQCW-- 376
CE+ N S +RS+P+ L + + +IT ++ +ST E S W
Sbjct: 216 ECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVSTFTCEPKSENYTYIWWL 275
Query: 377 -AESKP-GAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVK 434
+S P + +E+ LI+ ++T G Y C + G+ L
Sbjct: 276 NGQSLPVSPRVKRRIENRI-------LILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328
Query: 435 VVGP 438
+ GP
Sbjct: 329 LYGP 332
>gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [Homo
sapiens]
Length = 435
Score = 141 bits (355), Expect = 2e-33
Identities = 123/442 (27%), Positives = 192/442 (43%), Gaps = 61/442 (13%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+ P AQ+ + A P ++ +DV+L V P+ +
Sbjct: 15 WKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGY--------- 65
Query: 71 SIAVSPGTAIEQKDMVT---FYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILI 127
I K +T Y T+ V+ I + + R + + +L I
Sbjct: 66 ---------IWYKGQMTDLYHYITSYVVHGQIIY-----GPAYSGRETVYSNASLL-IQN 110
Query: 128 VQREDSGTYQCEARDALLSQRSDPI------FLDVKYGPDPVEIKLESGVASGEVVEVME 181
V +ED+G+Y + +R D F Y P S + EV+E +
Sbjct: 111 VTQEDAGSYTLH-----IIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVR 165
Query: 182 GSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVS 233
L P +Y W L L S T RT + V++ G Y C +
Sbjct: 166 ------LICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIR 219
Query: 234 NSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQP 293
N + S + + +L L MP + ++LN E + TC+ +++ W+L+GQ
Sbjct: 220 NPVS-ASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQS 278
Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITR 353
L S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L + YGPD I
Sbjct: 279 LPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRI-- 336
Query: 354 ESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGI 413
S +L L C+A+S P AEY WT+ + + G++L I +T H G+
Sbjct: 337 -----YPSFTYYRSGENLDLSCFADSNPPAEYSWTI-NGKFQLSGQKLFIPQITTNHSGL 390
Query: 414 YNCTASNSLTGLARSTSVLVKV 435
Y C+ NS TG S S++VKV
Sbjct: 391 YACSVRNSATGKEISKSMIVKV 412
Score = 93.6 bits (231), Expect = 5e-19
Identities = 69/228 (30%), Positives = 104/228 (45%), Gaps = 21/228 (9%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ V L + P+ P P I ++ E+KD++ F C K N
Sbjct: 220 NPVSASRSDPVTLNLL--PKLPM----------PYITINNLNPREKKDVLAFTCEPKSRN 267
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ R++ + +IL + V R ++G YQCE RD RS+P+ L+V
Sbjct: 268 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNV 327
Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
YGPD I G ++ S+PP Y+W + + F
Sbjct: 328 LYGPDLPRI-------YPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLF- 379
Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLN 264
I ++ H GLY C V NSAT ++ V+V ET + PQV + N
Sbjct: 380 IPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETAS-PQVTYAGPN 426
Score = 66.6 bits (161), Expect = 6e-11
Identities = 61/241 (25%), Positives = 96/241 (39%), Gaps = 22/241 (9%)
Query: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL-GTLKVRVLETLTMPQVVPSSLNLVEN 268
++ + I V++E G Y + + G V + P + S+LN E
Sbjct: 101 YSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREV 160
Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
+V L C + W L+GQ L + LQLS NRTL + G+ + GPY CE+ N
Sbjct: 161 MEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRN 220
Query: 329 WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWT 388
S +RS+P+ L + +IT + + E L C +S+ Y W
Sbjct: 221 PVSASRSDPVTLNLLPKLPMPYITINNLN------PREKKDVLAFTCEPKSR-NYTYIWW 273
Query: 389 LEHSTGEHL-----------GEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVG 437
L G+ L LI+ ++T G Y C + G+ + L + G
Sbjct: 274 L---NGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYG 330
Query: 438 P 438
P
Sbjct: 331 P 331
>gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1
[Homo sapiens]
Length = 335
Score = 128 bits (321), Expect = 2e-29
Identities = 78/235 (33%), Positives = 119/235 (50%), Gaps = 19/235 (8%)
Query: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTM------PQVVPSSL 263
++ + I V+RE G Y + GT V T T+ P + S+L
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHIIKRGD-----GTRGVTGYFTFTLYLETPKPSISSSNL 156
Query: 264 NLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYA 323
N E +V LTC + W+++GQ L + +QLS NRTL + G+ + GPY
Sbjct: 157 NPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYE 216
Query: 324 CEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGA 383
CE+WN GS +RS+P+ L + +GPD I S +L L C+A S P A
Sbjct: 217 CEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENLDLSCFANSNPPA 269
Query: 384 EYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGP 438
+Y WT+ + + G++L I +T +H+G+Y C+A NS TG STS+ ++V+ P
Sbjct: 270 QYSWTI-NGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIAP 323
Score = 81.6 bits (200), Expect = 2e-15
Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 8/185 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + + + W N S+ RMQLS+ + L +
Sbjct: 145 ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE ++ + RSDP+ L++ +GPD I V G ++
Sbjct: 205 FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENL 257
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
S+PP Y+W + + F I ++ +H GLY C NSAT S +L
Sbjct: 258 DLSCFANSNPPAQYSWTINGKFQLSGQKLF-IPQITPKHNGLYACSARNSATGEESSTSL 316
Query: 246 KVRVL 250
+RV+
Sbjct: 317 TIRVI 321
Score = 56.6 bits (135), Expect = 6e-08
Identities = 75/331 (22%), Positives = 125/331 (37%), Gaps = 53/331 (16%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQ----IHGRSRE 66
W G+LL+A L W+ P AQ+ + A P ++ +DV+L V P+ G+ R+
Sbjct: 15 WKGLLLTALLLNFWNLPTTAQVMIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L +T Y D I I+ + R + + +L I
Sbjct: 75 L---------------YHYITSYVV--DGQIIIY------GPAYSGRETVYSNASLL-IQ 110
Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
V RED+G+Y + +R D Y + ++ S + E
Sbjct: 111 NVTREDAGSYTLH-----IIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETV 165
Query: 187 FLAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSNSATH 238
L P +Y W++ LS T RT + V++ G Y C + NS +
Sbjct: 166 ILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNSGS- 224
Query: 239 LSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPS 297
S + + +L +P++ P S+ + ++DL+C N W ++G+
Sbjct: 225 ASRSDPVTLNLLHGPDLPRIFP-SVTSYYSGENLDLSCFANSNPPAQYSWTINGK----- 278
Query: 298 EHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + G YAC N
Sbjct: 279 --FQLS--GQKLFIPQITPKHNGLYACSARN 305
>gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2
[Homo sapiens]
Length = 213
Score = 126 bits (317), Expect = 5e-29
Identities = 67/183 (36%), Positives = 102/183 (55%), Gaps = 8/183 (4%)
Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
P + S+LN E +V LTC + W+++GQ L + +QLS NRTL + G+
Sbjct: 27 PSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVT 86
Query: 316 RNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQC 375
+ GPY CE+WN GS +RS+P+ L + +GPD I S +L L C
Sbjct: 87 KYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENLDLSC 139
Query: 376 WAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
+A S P A+Y WT+ + + G++L I +T +H+G+Y C+A NS TG STS+ ++V
Sbjct: 140 FANSNPPAQYSWTI-NGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRV 198
Query: 436 VGP 438
+ P
Sbjct: 199 IAP 201
Score = 81.6 bits (200), Expect = 2e-15
Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 8/185 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + + + W N S+ RMQLS+ + L +
Sbjct: 23 ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE ++ + RSDP+ L++ +GPD I V G ++
Sbjct: 83 FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENL 135
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
S+PP Y+W + + F I ++ +H GLY C NSAT S +L
Sbjct: 136 DLSCFANSNPPAQYSWTINGKFQLSGQKLF-IPQITPKHNGLYACSARNSATGEESSTSL 194
Query: 246 KVRVL 250
+RV+
Sbjct: 195 TIRVI 199
>gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2
[Homo sapiens]
Length = 213
Score = 126 bits (317), Expect = 5e-29
Identities = 67/183 (36%), Positives = 102/183 (55%), Gaps = 8/183 (4%)
Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
P + S+LN E +V LTC + W+++GQ L + +QLS NRTL + G+
Sbjct: 27 PSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVT 86
Query: 316 RNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQC 375
+ GPY CE+WN GS +RS+P+ L + +GPD I S +L L C
Sbjct: 87 KYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENLDLSC 139
Query: 376 WAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
+A S P A+Y WT+ + + G++L I +T +H+G+Y C+A NS TG STS+ ++V
Sbjct: 140 FANSNPPAQYSWTI-NGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRV 198
Query: 436 VGP 438
+ P
Sbjct: 199 IAP 201
Score = 81.6 bits (200), Expect = 2e-15
Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 8/185 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + + + W N S+ RMQLS+ + L +
Sbjct: 23 ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE ++ + RSDP+ L++ +GPD I V G ++
Sbjct: 83 FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENL 135
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
S+PP Y+W + + F I ++ +H GLY C NSAT S +L
Sbjct: 136 DLSCFANSNPPAQYSWTINGKFQLSGQKLF-IPQITPKHNGLYACSARNSATGEESSTSL 194
Query: 246 KVRVL 250
+RV+
Sbjct: 195 TIRVI 199
>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
6 (non-specific cross reacting antigen) [Homo sapiens]
Length = 344
Score = 126 bits (316), Expect = 6e-29
Identities = 84/245 (34%), Positives = 125/245 (51%), Gaps = 10/245 (4%)
Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC 276
I V++ G Y V S ++ T + V L P + ++ N VE+ +V TC
Sbjct: 109 IQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTC 167
Query: 277 QTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
+ Q+ W+++GQ L S LQLS N TL + ++RND G Y CE+ N S RS+
Sbjct: 168 EPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSD 227
Query: 337 PLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEH 396
P+ L + YGPD I+ A+ +L L C A S P A+Y W + + T +
Sbjct: 228 PVTLNVLYGPDGPTISPSKAN-------YRPGENLNLSCHAASNPPAQYSWFI-NGTFQQ 279
Query: 397 LGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGIL 456
++L I +T + G Y C A NS TGL R+T ++ V G + LS+ A GI IG+L
Sbjct: 280 STQELFIPNITVNNSGSYMCQAHNSATGLNRTTVTMITVSG-SAPVLSAVATVGITIGVL 338
Query: 457 AVIAV 461
A +A+
Sbjct: 339 ARVAL 343
Score = 105 bits (262), Expect = 1e-22
Identities = 60/175 (34%), Positives = 88/175 (50%), Gaps = 8/175 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
EL KPSI+ + +E KD V F C + N T W N S+ R+QLS LT+
Sbjct: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTL 202
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
L V+R D+G+Y+CE ++ + RSDP+ L+V YGPD I S G ++
Sbjct: 203 LSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDGPTI-------SPSKANYRPGENL 255
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
S+PP Y+WF ++ +T+ I ++ + G Y C NSAT L+
Sbjct: 256 NLSCHAASNPPAQYSWF-INGTFQQSTQELFIPNITVNNSGSYMCQAHNSATGLN 309
Score = 60.8 bits (146), Expect = 3e-09
Identities = 68/327 (20%), Positives = 124/327 (37%), Gaps = 47/327 (14%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W +LL+ASL T W+PP A+LT+ + P + + ++V+L P+ +
Sbjct: 15 WKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQN-----------RI 63
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
+ G ++ ++ Y I + R + + +L I V +
Sbjct: 64 GYSWYKGERVDGNSLIVGY--------VIGTQQATPGPAYSGRETIYPNASLL-IQNVTQ 114
Query: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
D+G Y + + L+++ + F P P ++S V + ++ F
Sbjct: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167
Query: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
E + W S+ LS+ T T+ +V R G Y C + N A+ S
Sbjct: 168 EPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRS- 226
Query: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
+ + VL P + PS N +++L+C N WF++G
Sbjct: 227 DPVTLNVLYGPDGPTISPSKAN-YRPGENLNLSCHAASNPPAQYSWFING---------T 276
Query: 302 LSADNRTLIIHGLQRNDTGPYACEVWN 328
+ L I + N++G Y C+ N
Sbjct: 277 FQQSTQELFIPNITVNNSGSYMCQAHN 303
>gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c
[Homo sapiens]
Length = 297
Score = 123 bits (309), Expect = 4e-28
Identities = 84/266 (31%), Positives = 128/266 (48%), Gaps = 20/266 (7%)
Query: 178 EVMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYR 229
E ME S+T ET P +Y W++ L S T RT + V++ G Y
Sbjct: 38 EAMEAVSLTCDPET---PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYE 94
Query: 230 CLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFL 289
C + N + S + +L L P + ++L EN ++ TC+ +++ W+L
Sbjct: 95 CEIRNPVS-ASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWL 153
Query: 290 SGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQV 349
+GQ L S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L + YGPD
Sbjct: 154 NGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLP 213
Query: 350 HITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWE 409
I S L L C A+S P A+Y WT+ + + G++L I +T +
Sbjct: 214 RI-------YPSFTYYRSGEVLYLSCSADSNPPAQYSWTI-NGKFQLSGQKLFIPQITTK 265
Query: 410 HDGIYNCTASNSLTGLARSTSVLVKV 435
H G+Y C+ NS TG S S+ VKV
Sbjct: 266 HSGLYACSVRNSATGKESSKSMTVKV 291
Score = 90.9 bits (224), Expect = 3e-18
Identities = 67/214 (31%), Positives = 100/214 (46%), Gaps = 22/214 (10%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ L + P+ P KP I ++ E KD++ F C K N
Sbjct: 99 NPVSASRSDPFTLNLL--PKLP----------KPYITINNLKPRENKDVLNFTCEPKSEN 146
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ R++ + +IL + V R ++G YQCE RD RS P+ L+V
Sbjct: 147 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 206
Query: 157 KYGPD-PVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTF 215
YGPD P + SGEV+ + S+PP Y+W + + F
Sbjct: 207 LYGPDLPRIYPSFTYYRSGEVLYLS--------CSADSNPPAQYSWTINGKFQLSGQKLF 258
Query: 216 TIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
I ++ +H GLY C V NSAT S ++ V+V
Sbjct: 259 -IPQITTKHSGLYACSVRNSATGKESSKSMTVKV 291
Score = 67.8 bits (164), Expect = 3e-11
Identities = 56/195 (28%), Positives = 83/195 (42%), Gaps = 23/195 (11%)
Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
P + S LN E +V LTC + W+++GQ L S LQLS NRTL + G+
Sbjct: 27 PSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVT 86
Query: 316 RNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSS-LTLQ 374
+ GPY CE+ N S +RS+P L + + +IT I+ ++ N L
Sbjct: 87 KYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYIT-------INNLKPRENKDVLNFT 139
Query: 375 CWAESKPGAEYRWTLEHSTGEHL-----------GEQLIIRALTWEHDGIYNCTASNSLT 423
C +S+ Y W L G+ L LI+ ++T G Y C +
Sbjct: 140 CEPKSE-NYTYIWWL---NGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYG 195
Query: 424 GLARSTSVLVKVVGP 438
G+ L + GP
Sbjct: 196 GIRSYPVTLNVLYGP 210
Score = 65.1 bits (157), Expect = 2e-10
Identities = 68/273 (24%), Positives = 114/273 (41%), Gaps = 29/273 (10%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V+ C + + + W N S+ R+QLS+ + L +
Sbjct: 23 ETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFL 82
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS- 184
L V + +G Y+CE R+ + + RSDP L++ KL + ++ E
Sbjct: 83 LGVTKYTAGPYECEIRNPVSASRSDPFTLNLL-------PKLPKPYITINNLKPRENKDV 135
Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
+ F E KS Y W+L L + R + +V+R G Y+C + +
Sbjct: 136 LNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQY 194
Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQT-VNQSVNVQWFLSGQPLL 295
+ S + + VL +P++ P S + + L+C N W ++G+
Sbjct: 195 GGIRSY-PVTLNVLYGPDLPRIYP-SFTYYRSGEVLYLSCSADSNPPAQYSWTINGK--- 249
Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + +G YAC V N
Sbjct: 250 ----FQLS--GQKLFIPQITTKHSGLYACSVRN 276
>gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo
sapiens]
Length = 335
Score = 121 bits (303), Expect = 2e-27
Identities = 78/233 (33%), Positives = 114/233 (48%), Gaps = 19/233 (8%)
Query: 209 SHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTM------PQVVPSS 262
+++ + I V+RE G Y + GT V T T+ P + S+
Sbjct: 101 AYSNASLLIQNVTREDAGSYTLHIIKRGD-----GTRGVTGYFTFTLYLETPKPSISSSN 155
Query: 263 LNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPY 322
LN E +V LTC + QW+++GQ L + QLS NRTL + G+ + GPY
Sbjct: 156 LNPREAMETVILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPY 215
Query: 323 ACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPG 382
CE+ N GS +RS+P+ L + +GPD I S +L L C+A S P
Sbjct: 216 ECEIRNSGSASRSDPVTLNLLHGPDLPRIHP-------SYTNYRSGDNLYLSCFANSNPP 268
Query: 383 AEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
A+Y WT+ + + G+ L I +T +H G+Y C+ NS TG STS+ VKV
Sbjct: 269 AQYSWTI-NGKFQQSGQNLFIPQITTKHSGLYVCSVRNSATGEESSTSLTVKV 320
Score = 82.0 bits (201), Expect = 1e-15
Identities = 53/184 (28%), Positives = 85/184 (46%), Gaps = 8/184 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + + + W N S+ R QLS+ + L +
Sbjct: 145 ETPKPSISSSNLNPREAMETVILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE R++ + RSDP+ L++ +GPD I G ++
Sbjct: 205 FGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGPDLPRI-------HPSYTNYRSGDNL 257
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
S+PP Y+W ++ + + I ++ +H GLY C V NSAT S +L
Sbjct: 258 YLSCFANSNPPAQYSW-TINGKFQQSGQNLFIPQITTKHSGLYVCSVRNSATGEESSTSL 316
Query: 246 KVRV 249
V+V
Sbjct: 317 TVKV 320
Score = 58.5 bits (140), Expect = 2e-08
Identities = 75/331 (22%), Positives = 125/331 (37%), Gaps = 53/331 (16%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQ----IHGRSRE 66
W G+L++ASL W+ P AQ+T+ A P ++ +DV+L V P+ G+ R+
Sbjct: 15 WKGLLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L +T Y D I I+ + + + + L I
Sbjct: 75 L---------------YHYITSYVV--DGQIIIYGPA-------YSGRETAYSNASLLIQ 110
Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
V RED+G+Y + +R D Y + ++ S + E
Sbjct: 111 NVTREDAGSYTLH-----IIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETV 165
Query: 187 FLAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSNSATH 238
L P +Y W++ LS T RT + V++ G Y C + NS +
Sbjct: 166 ILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGS- 224
Query: 239 LSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPS 297
S + + +L +P++ PS N + ++ L+C N W ++G+
Sbjct: 225 ASRSDPVTLNLLHGPDLPRIHPSYTN-YRSGDNLYLSCFANSNPPAQYSWTINGK----- 278
Query: 298 EHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
Q S N L I + +G Y C V N
Sbjct: 279 --FQQSGQN--LFIPQITTKHSGLYVCSVRN 305
>gi|21314600 carcinoembryonic antigen-related cell adhesion molecule
8 [Homo sapiens]
Length = 349
Score = 117 bits (293), Expect = 3e-26
Identities = 73/210 (34%), Positives = 111/210 (52%), Gaps = 12/210 (5%)
Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
P + ++ N VE+ +V TC+ Q+ W+++GQ L S LQLS NRTL + +
Sbjct: 147 PSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVT 206
Query: 316 RNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQC 375
RND GPY CE+ N S S+P+ L + YGPD I+ S +L L C
Sbjct: 207 RNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISP-------SDTYYHAGVNLNLSC 259
Query: 376 WAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
A S P ++Y W++ + T + ++L I +T ++ G Y C +NS TG R+T ++ V
Sbjct: 260 HAASNPPSQYSWSV-NGTFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITV 318
Query: 436 ----VGPQSSSLSSGAIAGIVIGILAVIAV 461
V S LS+ A I+IG+LA +A+
Sbjct: 319 SDALVQGSSPGLSARATVSIMIGVLARVAL 348
Score = 95.9 bits (237), Expect = 9e-20
Identities = 57/172 (33%), Positives = 84/172 (48%), Gaps = 8/172 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ + +E KD V F C + N T W N S+ R+QLS + LT+
Sbjct: 143 ETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTL 202
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
L V R D G Y+CE ++ + SDP+ L+V YGPD I S G ++
Sbjct: 203 LSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTI-------SPSDTYYHAGVNL 255
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSAT 237
S+PP Y+W + + +T + F I ++ ++ G Y C +NSAT
Sbjct: 256 NLSCHAASNPPSQYSWSVNGTFQQYTQKLF-IPNITTKNSGSYACHTTNSAT 306
Score = 72.8 bits (177), Expect = 8e-13
Identities = 77/335 (22%), Positives = 135/335 (40%), Gaps = 47/335 (14%)
Query: 3 PADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHG 62
P+ W W G+LL+ASL T W+PP AQLT+ A P +A + ++V+L V P+ P+ +
Sbjct: 7 PSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYN 66
Query: 63 RSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKI 122
+ G ++ + Y + IT +N ++ L ++
Sbjct: 67 WYK-----------GETVDANRRIIGYVISNQ-QITPGPAYSNRETIYPNASLLMRN--- 111
Query: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182
V R D+G+Y + L+ S+ + P+ + + S + VE +
Sbjct: 112 -----VTRNDTGSYTLQV--IKLNLMSEEVTGQFSVHPETPKPSISSN--NSNPVEDKDA 162
Query: 183 SSMTFLAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSN 234
+ T ET++ Y W++ LS+ RT T+ +V+R G Y C + N
Sbjct: 163 VAFTCEPETQN---TTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQN 219
Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQP 293
A+ S + + VL P + PS +++L+C N W ++G
Sbjct: 220 PASANFS-DPVTLNVLYGPDAPTISPSD-TYYHAGVNLNLSCHAASNPPSQYSWSVNG-- 275
Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
+ L I + ++G YAC N
Sbjct: 276 -------TFQQYTQKLFIPNITTKNSGSYACHTTN 303
>gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2
[Homo sapiens]
Length = 326
Score = 116 bits (291), Expect = 5e-26
Identities = 68/180 (37%), Positives = 98/180 (54%), Gaps = 8/180 (4%)
Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
P + S+LN E +V LTC + + QW+++GQ L + LQLS NRTL I G+
Sbjct: 149 PSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVT 208
Query: 316 RNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQC 375
+ GPY CE+ N S +RS+P+ L + +GPD I S +L L C
Sbjct: 209 KYIAGPYECEIRNPVSASRSDPVTLNLLHGPDLPSI-------YPSFTYYRSGENLYLSC 261
Query: 376 WAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
+AES P A+Y WT+ + + G++L I +T +H G+Y C+ NS TG S S+ VKV
Sbjct: 262 FAESNPRAQYSWTI-NGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSITVKV 320
Score = 79.7 bits (195), Expect = 7e-15
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 8/184 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + W N S+ R+QLSK + L I
Sbjct: 145 ETPKPSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFI 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE R+ + + RSDP+ L++ +GPD L S S E +
Sbjct: 205 FGVTKYIAGPYECEIRNPVSASRSDPVTLNLLHGPD-----LPSIYPSFTYYRSGENLYL 259
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ AE S+P Y+W ++ + + +I ++ +H GLY C V NSAT S ++
Sbjct: 260 SCFAE--SNPRAQYSW-TINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSI 316
Query: 246 KVRV 249
V+V
Sbjct: 317 TVKV 320
Score = 57.8 bits (138), Expect = 3e-08
Identities = 71/330 (21%), Positives = 125/330 (37%), Gaps = 51/330 (15%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+PP AQ+T+ A P ++ +DV+L V P+
Sbjct: 15 WKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ-------------- 60
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVF---HERMQLSKDGKILTILI 127
+ I K +T+ + +V + +++ + + L I
Sbjct: 61 ----NLAGYIWYKGQMTYL-----YHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQN 111
Query: 128 VQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTF 187
V +ED+G+Y + +R D + + ++ S + E
Sbjct: 112 VTQEDAGSYTLH-----IIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVI 166
Query: 188 LAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
L + P +Y W++ LS T RT I V++ G Y C + N +
Sbjct: 167 LTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVS-A 225
Query: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPSE 298
S + + +L +P + P S + ++ L+C N W ++G+
Sbjct: 226 SRSDPVTLNLLHGPDLPSIYP-SFTYYRSGENLYLSCFAESNPRAQYSWTINGK------ 278
Query: 299 HLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + +G YAC V N
Sbjct: 279 -FQLS--GQKLSIPQITTKHSGLYACSVRN 305
>gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo
sapiens]
Length = 335
Score = 110 bits (274), Expect = 5e-24
Identities = 70/230 (30%), Positives = 111/230 (48%), Gaps = 9/230 (3%)
Query: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL-GTLKVRVLETLTMPQVVPSSLNLVEN 268
++ + I V+RE G Y + + G + L P + ++ EN
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPREN 161
Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
+ TC+ +++ W+L+GQ L S ++ +NR LI+ + RN+TGPY CE+ +
Sbjct: 162 KDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRD 221
Query: 329 WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWT 388
RS+P+ L + YGPD I S +L L C+AES P AEY WT
Sbjct: 222 RDGGMRSDPVTLNVLYGPDLPSI-------YPSFTYYRSGENLYLSCFAESNPPAEYFWT 274
Query: 389 LEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGP 438
+ + + G++L I +T +H G+Y C+ NS TG S S+ V+V P
Sbjct: 275 I-NGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAP 323
Score = 92.8 bits (229), Expect = 8e-19
Identities = 61/184 (33%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
+L KP I ++ E KD++ F C K N T W N S+ R++ + +IL +
Sbjct: 145 KLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILIL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V R ++G Y+CE RD RSDP+ L+V YGPD L S S E +
Sbjct: 205 PSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD-----LPSIYPSFTYYRSGENLYL 259
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ AE S+PP Y W ++ + + +I ++ +H GLY C V NSAT S ++
Sbjct: 260 SCFAE--SNPPAEYFW-TINGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSM 316
Query: 246 KVRV 249
V V
Sbjct: 317 TVEV 320
Score = 46.6 bits (109), Expect = 7e-05
Identities = 71/328 (21%), Positives = 119/328 (36%), Gaps = 47/328 (14%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+ P AQ+T+ A P ++ +DV+L V P+
Sbjct: 15 WKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQN-----------LA 63
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
G ++ +T Y +NI + R + + +L I V R
Sbjct: 64 GYIWYKGQLMDLYHYITSYVVDGQINI--------YGPAYTGRETVYSNASLL-IQNVTR 114
Query: 131 EDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS-MTFLA 189
ED+G+Y + +R D Y + +KL + + E + F
Sbjct: 115 EDAGSYTLH-----IIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTC 169
Query: 190 ETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSATHLSS 241
E KS Y W+L L + R + +V+R G Y C + + + S
Sbjct: 170 EPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRS 228
Query: 242 LGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPSEHL 300
+ + VL +P + P S + ++ L+C N W ++G
Sbjct: 229 -DPVTLNVLYGPDLPSIYP-SFTYYRSGENLYLSCFAESNPPAEYFWTING--------- 277
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWN 328
+ + L I + G Y C V N
Sbjct: 278 KFQQSGQKLSIPQITTKHRGLYTCSVRN 305
>gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo
sapiens]
Length = 335
Score = 110 bits (274), Expect = 5e-24
Identities = 70/230 (30%), Positives = 111/230 (48%), Gaps = 9/230 (3%)
Query: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL-GTLKVRVLETLTMPQVVPSSLNLVEN 268
++ + I V+RE G Y + + G + L P + ++ EN
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPREN 161
Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
+ TC+ +++ W+L+GQ L S ++ +NR LI+ + RN+TGPY CE+ +
Sbjct: 162 KDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRD 221
Query: 329 WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWT 388
RS+P+ L + YGPD I S +L L C+AES P AEY WT
Sbjct: 222 RDGGMRSDPVTLNVLYGPDLPSI-------YPSFTYYRSGENLYLSCFAESNPPAEYFWT 274
Query: 389 LEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGP 438
+ + + G++L I +T +H G+Y C+ NS TG S S+ V+V P
Sbjct: 275 I-NGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAP 323
Score = 92.8 bits (229), Expect = 8e-19
Identities = 61/184 (33%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
+L KP I ++ E KD++ F C K N T W N S+ R++ + +IL +
Sbjct: 145 KLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILIL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V R ++G Y+CE RD RSDP+ L+V YGPD L S S E +
Sbjct: 205 PSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD-----LPSIYPSFTYYRSGENLYL 259
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ AE S+PP Y W ++ + + +I ++ +H GLY C V NSAT S ++
Sbjct: 260 SCFAE--SNPPAEYFW-TINGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSM 316
Query: 246 KVRV 249
V V
Sbjct: 317 TVEV 320
Score = 46.6 bits (109), Expect = 7e-05
Identities = 71/328 (21%), Positives = 119/328 (36%), Gaps = 47/328 (14%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+ P AQ+T+ A P ++ +DV+L V P+
Sbjct: 15 WKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQN-----------LA 63
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
G ++ +T Y +NI + R + + +L I V R
Sbjct: 64 GYIWYKGQLMDLYHYITSYVVDGQINI--------YGPAYTGRETVYSNASLL-IQNVTR 114
Query: 131 EDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS-MTFLA 189
ED+G+Y + +R D Y + +KL + + E + F
Sbjct: 115 EDAGSYTLH-----IIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTC 169
Query: 190 ETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSATHLSS 241
E KS Y W+L L + R + +V+R G Y C + + + S
Sbjct: 170 EPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRS 228
Query: 242 LGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPSEHL 300
+ + VL +P + P S + ++ L+C N W ++G
Sbjct: 229 -DPVTLNVLYGPDLPSIYP-SFTYYRSGENLYLSCFAESNPPAEYFWTING--------- 277
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWN 328
+ + L I + G Y C V N
Sbjct: 278 KFQQSGQKLSIPQITTKHRGLYTCSVRN 305
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 87.4 bits (215), Expect = 3e-17
Identities = 97/358 (27%), Positives = 138/358 (38%), Gaps = 48/358 (13%)
Query: 98 TIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSD------- 150
TI W + V R+Q+ +G++L I Q DSG Y C A + D
Sbjct: 1479 TIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQV 1538
Query: 151 -PIFLDVKYGPDPVEIKLESGVASGEVVE---VMEGSSMTFLAETKSHPPCAYTWFLLDS 206
P+F V EI A G V E ++E + +T + PP TW+ D
Sbjct: 1539 PPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQ 1598
Query: 207 ILS--------HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQV 258
LS R I V E+ G Y C SN L +L LT P +
Sbjct: 1599 PLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGE----DWLHYELL-VLTPPVI 1653
Query: 259 VPSSLNLVE----NARS-VDLTCQTVNQSV-NVQWFLSGQPLLPSEHLQLSADNRTLIIH 312
+ + LVE NA S V L C + V + W +G P PS LQ+ D + L +
Sbjct: 1654 LGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVS 1713
Query: 313 GLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT 372
+ D Y C N +A S T+ +V + A + + A LNSS++
Sbjct: 1714 TAEVADAASYMCVAEN---QAGSAEKLFTL-----RVQVPPRIAGLDLEQVTAILNSSVS 1765
Query: 373 LQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALT---------WEHDGIYNCTASNS 421
L C + P E W + S LGE++ + T G+Y C A N+
Sbjct: 1766 LPCDVHAHPNPEVTW-YKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNA 1822
Score = 84.0 bits (206), Expect = 4e-16
Identities = 91/363 (25%), Positives = 139/363 (38%), Gaps = 36/363 (9%)
Query: 98 TIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF-LDV 156
TI W+ N L R+Q+ +DG++L + + D+ +Y C A + S ++ +F L V
Sbjct: 1685 TISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGS--AEKLFTLRV 1742
Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILS------- 209
+ P + LE V + SS++ + +HP TW+ LS
Sbjct: 1743 QVPPRIAGLDLEQ-------VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFL 1795
Query: 210 -HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268
T T + G+Y C N+A L L V V P LV
Sbjct: 1796 LPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRV 1855
Query: 269 ARSVDLTCQT-VNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVW 327
L+C+T V W+ GQPL+ ++ Q + L I Q +D G Y+C+V
Sbjct: 1856 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVS 1915
Query: 328 NWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW 387
N A LT+ P + E+ S++ S L L C P W
Sbjct: 1916 NVAGEA-VRTFTLTVQVPPTFENPKTETVSQV-------AGSPLVLTCDVSGVPAPTVTW 1967
Query: 388 TLE----HSTGEH----LGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQ 439
+ S+ H G +L + L G Y C A N+ AR V+ +V P+
Sbjct: 1968 LKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENT-QAEARKDFVVAVLVAPR 2026
Query: 440 SSS 442
S
Sbjct: 2027 IRS 2029
Score = 72.8 bits (177), Expect = 8e-13
Identities = 86/361 (23%), Positives = 141/361 (39%), Gaps = 39/361 (10%)
Query: 99 IHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
I W V E L G +L + Q +DSG Y C A + R + ++V
Sbjct: 1193 IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRN-FSVEVLV 1251
Query: 159 GPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWF-----LLDSILSHTTR 213
P LE EV++V++G + + HP TWF L H +
Sbjct: 1252 PPSIENEDLE------EVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISP 1305
Query: 214 TFTIHAVSREH---EGLYRCLVSNSATHLSSLGTLKVRVLETL------TMPQVVPSSLN 264
+ V + + G Y C+ +N+ + L V + T+ + + V ++N
Sbjct: 1306 DGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVN 1365
Query: 265 LVENARSVDLTCQTVN-QSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYA 323
+ L C+ + S N+ W G P S ++QL L I Q+ D G Y
Sbjct: 1366 -----NPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYT 1420
Query: 324 CEVWN-WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPG 382
C V N G ++ +E+ I P + + ++ ++NS+LTL+C + + P
Sbjct: 1421 CVVTNELGEAVKNYHVEVLI---PPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPP 1477
Query: 383 AEYRW------TLEHSTGEHLGE--QLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVK 434
RW S + LGE L I+ G Y C A+N + +VL++
Sbjct: 1478 PTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ 1537
Query: 435 V 435
V
Sbjct: 1538 V 1538
Score = 66.6 bits (161), Expect = 6e-11
Identities = 82/318 (25%), Positives = 122/318 (38%), Gaps = 42/318 (13%)
Query: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182
L I V D G Y C A + L + + L V P+ +E G + V +E
Sbjct: 659 LQIEKVDLRDEGIYTCAATN-LAGESKREVALKVLVPPN-----IEPGPVNKAV---LEN 709
Query: 183 SSMTFLAETKSHPPCAYTWFL--------LDSILSHTTRTFTIHAVSREHEGLYRCLVSN 234
+S+T PP +WF + +S R I G YRC+ SN
Sbjct: 710 ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 769
Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQ-TVNQSVNVQWFLSGQP 293
A L+V V +T+P +P + LV V LTC T S + W G P
Sbjct: 770 VAGSTELRYGLRVNVPPRITLPPSLPGPV-LVNT--PVRLTCNATGAPSPTLMWLKDGNP 826
Query: 294 LLP--SEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHI 351
+ P + LQ+ R L + + +D+G Y+C + R + + QVH+
Sbjct: 827 VSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL--------QVHM 878
Query: 352 TRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW-----TLEHSTGEHLGEQLII--- 403
E ++ + N S+ L+C + + P W LE G HL +
Sbjct: 879 PPSILGEELN-VSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQV 937
Query: 404 -RALTWEHDGIYNCTASN 420
RA W+ G Y C A N
Sbjct: 938 DRADVWD-AGHYTCEALN 954
Score = 66.6 bits (161), Expect = 6e-11
Identities = 95/366 (25%), Positives = 140/366 (38%), Gaps = 46/366 (12%)
Query: 98 TIHWVS--NNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLD 155
T+ W+ N +S +Q+ G++LT+ + DSG Y C A A+ R D + L
Sbjct: 817 TLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD-VVLQ 875
Query: 156 VKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSH--PPCAYTWFLLDSILS---- 209
V P + +L V + E V + E +SH PP +W+ L
Sbjct: 876 VHMPPSILGEELNVSVVANESVAL----------ECQSHAMPPPVLSWWKDGRPLEPRPG 925
Query: 210 -HTTRTFTIHAVSRE---HEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNL 265
H + + V R G Y C N A L V V + + S
Sbjct: 926 VHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRE---SHTLT 982
Query: 266 VENARSVDLTCQTVNQSV-NVQWFLSGQPLLPSEHLQL---SADNRTLIIHGLQRNDTGP 321
V L+C+ + W GQP LP E L SA R L + Q G
Sbjct: 983 VREGHPTSLSCECRGVPFPKISWRKDGQP-LPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 1041
Query: 322 YACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKP 381
Y CE N + S+ L+L ++ P Q+ RE ++ +S ++ + TL+C A KP
Sbjct: 1042 YTCECSNVVGNS-SQDLQLEVHV-PPQIAGPREPPTQ-VSVVQ---DGVATLECNATGKP 1095
Query: 382 GAEYRWTLE-HSTGEHL-------GEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLV 433
W + G L G+ L + H G Y+C A N L G A L
Sbjct: 1096 PPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN-LAGRAERKFELS 1154
Query: 434 KVVGPQ 439
+V P+
Sbjct: 1155 VLVPPE 1160
Score = 66.6 bits (161), Expect = 6e-11
Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 23/238 (9%)
Query: 99 IHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
I W N+ V E + G L V REDSGTY C A + + + F+ VK
Sbjct: 2969 IGWTVNDRPVT--EGVSEQDGGSTLQRAAVSREDSGTYVCWAENR-VGRTQAVSFVHVKE 3025
Query: 159 GPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWF-----LLDSILSHTTR 213
P + G A +VE + G S+ + P W L S L H +
Sbjct: 3026 AP------VLQGEAFSYLVEPV-GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ 3078
Query: 214 --TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARS 271
+ TIH R+ G Y+CL N + + + VL++ + QV P + V +
Sbjct: 3079 NGSLTIHRTERDDAGRYQCLAEN---EMGVAKKVVILVLQSAPVFQVEPQDMT-VRSGDD 3134
Query: 272 VDLTCQTVNQ-SVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
V L CQ + + ++W +GQPL S L+ D +L + ++ D G Y C N
Sbjct: 3135 VALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG-SLWLENVETGDAGTYDCVAHN 3191
Score = 65.1 bits (157), Expect = 2e-10
Identities = 77/324 (23%), Positives = 115/324 (35%), Gaps = 32/324 (9%)
Query: 114 MQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVAS 173
+Q+ +DG++L I D G YQC A Q D F + P + E+G
Sbjct: 265 LQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARD--FQLRVHAPPTIWGSNETG--- 319
Query: 174 GEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTT--------RTFTIHAVSREHE 225
V VME + L E + P TWF ++L +T R +
Sbjct: 320 --EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDA 377
Query: 226 GLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVN 284
G+Y C SN+ L V V T+ P + V R V L C + S
Sbjct: 378 GVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVA-GRPVALECVARGHPSPT 436
Query: 285 VQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINY 344
+ W G P+ S +L D L + +G Y+C A S E + Y
Sbjct: 437 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCV-------ASSPAGEAVLQY 489
Query: 345 GPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHL------- 397
+ + +E + + + L L C A P +W E L
Sbjct: 490 SVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVAS 549
Query: 398 -GEQLIIRALTWEHDGIYNCTASN 420
G L I + +H G++ C A+N
Sbjct: 550 QGTTLHIDHVELDHSGLFACQATN 573
Score = 63.9 bits (154), Expect = 4e-10
Identities = 88/386 (22%), Positives = 157/386 (40%), Gaps = 38/386 (9%)
Query: 79 AIEQKDMVTFYCTTKDV---NITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGT 135
A+ + +V C + V NIT W + + ++ ++ G+ L + Q D+G
Sbjct: 322 AVMEDHLVQLLCEARGVPTPNIT--WFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGV 379
Query: 136 YQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHP 195
Y C+A +A+ LDV P +E VV+ + G + + HP
Sbjct: 380 YTCKASNAV-GAAEKATRLDVYVPPT-----IEGAGGRPYVVKAVAGRPVALECVARGHP 433
Query: 196 PCAYTWFL--LDSILSHTTRTFTIHAVSR------EHEGLYRCLVSNSATHLSSLGTLKV 247
+W L S+ +R T +V R GLY C+ S+ A +++V
Sbjct: 434 SPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEV 493
Query: 248 RVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSV-NVQWFLSGQPLLPSEHLQLSADN 306
+V L + + + +V + ++L CQ V +QW +G+P +Q+++
Sbjct: 494 QVPPQLLVAEGLGQVTTIV--GQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQG 551
Query: 307 RTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN--YGPDQVHI---TRESASEMIS 361
TL I ++ + +G +AC+ N A +E +E++++ + P + + E S
Sbjct: 552 TTLHIDHVELDHSGLFACQATNEAGTAGAE-VEVSVHGEWAPGVLEVPIGQYHWGXEHHS 610
Query: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST-GEHLG--------EQLIIRALTWEHDG 412
+ A + + A KP W S GE G L I + +G
Sbjct: 611 SFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEG 670
Query: 413 IYNCTASNSLTGLARSTSVLVKVVGP 438
IY C A+N L G ++ L +V P
Sbjct: 671 IYTCAATN-LAGESKREVALKVLVPP 695
Score = 62.8 bits (151), Expect = 9e-10
Identities = 81/366 (22%), Positives = 144/366 (39%), Gaps = 45/366 (12%)
Query: 96 NITIH------WVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRS 149
N+T H W + + + +S DG +L +L +G Y C A +A+ +++
Sbjct: 1277 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAV-GEKT 1335
Query: 150 DPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILS 209
L V P + +S + E V V + ++ + E + P TW + D
Sbjct: 1336 KHFQLSVLLAPTILGGAEDS---ADEEVTVTVNNPISLICEALAFPSPNITW-MKDGAPF 1391
Query: 210 HTTRTFTI----HAVS-----REHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVP 260
+R + H + +E G Y C+V+N ++V + +++ +
Sbjct: 1392 EASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLG 1451
Query: 261 S-SLNLVENARSVDLTCQTVNQSV---NVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQR 316
+ V+ + LT + + +V ++W+ GQP+ PS LQ+ + R L I Q
Sbjct: 1452 EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQV 1511
Query: 317 NDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT---- 372
+D+G Y C N + + I P + SA+ I + E E +T
Sbjct: 1512 SDSGRYLCVATNVAGE-DDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYRE 1570
Query: 373 --------LQCWAESKPGAEYRWTLEH---STGEHL-----GEQLIIRALTWEHDGIYNC 416
L C + P + W E S G+ + G L I + E+ G Y+C
Sbjct: 1571 IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSC 1630
Query: 417 TASNSL 422
ASN +
Sbjct: 1631 KASNEV 1636
Score = 62.0 bits (149), Expect = 1e-09
Identities = 106/471 (22%), Positives = 168/471 (35%), Gaps = 61/471 (12%)
Query: 7 WGHHWMGILLSA--SLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRS 64
WG H L+ S ++W P + + P + D+ T + G S
Sbjct: 624 WGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGES 683
Query: 65 RE------LAKPSIAVSP-GTAIEQKDMVTFYCTTKDVNIT-IHWVSNNLSVVFHERMQL 116
+ L P+I P A+ + VT C V + W + V + +
Sbjct: 684 KREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTV 743
Query: 117 SKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYG---PDPVEIKLESGVAS 173
S DG++L I Q D+G+Y+C A + S +++YG P I L +
Sbjct: 744 SVDGRVLRIEQAQLSDAGSYRCVASNVAGS-------TELRYGLRVNVPPRITLPPSLPG 796
Query: 174 GEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHT----------TRTFTIHAVSRE 223
V+ + + P W + +S R T+ +
Sbjct: 797 ----PVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARAS 852
Query: 224 HEGLYRCLVSNSATHLSSLGTLKVRVLETLTM-PQVVPSSLNL-VENARSVDLTCQTVNQ 281
G Y C+ +S++G + V+ + M P ++ LN+ V SV L CQ+
Sbjct: 853 DSGRYSCVA------VSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAM 906
Query: 282 SVNV-QWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLEL 340
V W+ G+PL P + LSAD L + D G Y CE N R+
Sbjct: 907 PPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEK---HY 963
Query: 341 TINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQ 400
+N V RES + T+ +SL+ +C P +R + GE G Q
Sbjct: 964 NLNVWVAPVFPLRESHT---LTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQ 1020
Query: 401 --------LIIRALTWEHDGIYNCTAS----NSLTGLARSTSVLVKVVGPQ 439
L + +G Y C S NS L V ++ GP+
Sbjct: 1021 HVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPR 1071
Score = 62.0 bits (149), Expect = 1e-09
Identities = 90/367 (24%), Positives = 129/367 (35%), Gaps = 50/367 (13%)
Query: 96 NITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEA-----RDALLSQRS- 149
N + W ++ ++ E + L L + + DSG Y CEA RD L Q S
Sbjct: 1775 NPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSV 1834
Query: 150 --DPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI 207
P F GP + V V G ET + P TW+
Sbjct: 1835 LVPPAFRQAPRGPQ-------------DAVLVRVGDKAVLSCETDALPEPTVTWYKDGQP 1881
Query: 208 LSHTTRTFTIHAVSR--------EHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVV 259
L RT + R +GLY C VSN A TL V+V T P+
Sbjct: 1882 LVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKT- 1940
Query: 260 PSSLNLVENARSVDLTCQTVN-QSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRND 318
+++ V + V LTC + V W P+ S + + L + LQ
Sbjct: 1941 -ETVSQVAGSPLV-LTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQ 1998
Query: 319 TGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAE 378
G Y C N + AR + + + P I + +E + + L C A+
Sbjct: 1999 AGTYTCVAENTQAEARKD-FVVAVLVAP---RIRSSGVAREHHVLEGQ---EVRLDCEAD 2051
Query: 379 SKPGAEYRW-----TLEHSTGEHL-----GEQLIIRALTWEHDGIYNCTASNSLTGLARS 428
+P + W L G HL G L+++ L G Y C A N AR
Sbjct: 2052 GQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARL 2111
Query: 429 TSVLVKV 435
+V V V
Sbjct: 2112 HTVNVLV 2118
Score = 61.6 bits (148), Expect = 2e-09
Identities = 90/414 (21%), Positives = 149/414 (35%), Gaps = 65/414 (15%)
Query: 62 GRSRELAKPSIAVSPG-----------TAIEQKDMVTFYCTTKDV-NITIHWVSNNLSVV 109
GR ++L + S+ V P + D C T + T+ W + +V
Sbjct: 1824 GRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLV 1883
Query: 110 FHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLES 169
+R Q + G+ L I Q D G Y C+ + + + L V+ P K E+
Sbjct: 1884 LAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSN-VAGEAVRTFTLTVQVPPTFENPKTET 1942
Query: 170 GVASGEVVEVMEGSSMTFLAETKSHPPCAYTWF---------LLDSILSHTTRTFTIHAV 220
V + GS + + P TW + ++S R + +
Sbjct: 1943 -------VSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGR-LQLSRL 1994
Query: 221 SREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSL---NLVENARSVDLTCQ 277
G Y C+ N+ K V+ L P++ S + + V + V L C+
Sbjct: 1995 QPAQAGTYTCVAENTQAEAR-----KDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCE 2049
Query: 278 TVNQSV-NVQWFLSGQPLLPS--EHLQLSADNRTLIIHGLQRNDTGPYACEVWN-WGSRA 333
Q +V W G PL HL+ D +L++ GL+ +D G Y C N G A
Sbjct: 2050 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDA 2109
Query: 334 RSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW------ 387
R T+N V T + ++ T+ + +T+ C P W
Sbjct: 2110 RLH----TVNV---LVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLP 2162
Query: 388 ------TLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
TL H + G L I + GI+ C A++ R+ ++ V+V
Sbjct: 2163 LPLSQRTLLHGS----GHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQV 2212
Score = 52.4 bits (124), Expect = 1e-06
Identities = 82/354 (23%), Positives = 129/354 (36%), Gaps = 56/354 (15%)
Query: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182
L + ++ +D+GTY C A +A+ R + L + P + + + G+
Sbjct: 2902 LLVKNLEGQDAGTYTCTAENAVGRARRR-VHLTILVLPVFTTLPGDRSLRLGD------- 2953
Query: 183 SSMTFLAETKSHPPCAYTWFLLDSILSHTTR------TFTIHAVSREHEGLYRCLVSNSA 236
+ + P W + D ++ T AVSRE G Y C N
Sbjct: 2954 -RLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRV 3012
Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSV-NVQWFLSGQPLL 295
++ + V+ L Q S + S+ L C V ++ W G PL
Sbjct: 3013 GRTQAVSFVHVKEAPVL---QGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR 3069
Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARS--------------EPLELT 341
S HL+ N +L IH +R+D G Y C N A+ EP ++T
Sbjct: 3070 GS-HLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMT 3128
Query: 342 INYGPDQVHITRESASEMISTIE-AELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQ 400
+ G D V + ++ E TIE + L + P W TG+
Sbjct: 3129 VRSG-DDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSL-WLENVETGD----- 3181
Query: 401 LIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIG 454
G Y+C A N L G A + + LV PQ S G++ G++ G
Sbjct: 3182 ----------AGTYDCVAHN-LLGSATARAFLVVRGEPQG---SWGSMTGVING 3221
Score = 51.2 bits (121), Expect = 3e-06
Identities = 70/329 (21%), Positives = 116/329 (35%), Gaps = 41/329 (12%)
Query: 116 LSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGE 175
+S G++L + Q GTY CE + ++ S + L+V P ++
Sbjct: 1022 VSAVGRLLYLGQAQLAQEGTYTCECSN-VVGNSSQDLQLEVHVPP-----QIAGPREPPT 1075
Query: 176 VVEVMEGSSMTFLAETKSHPPCAYTWFL--------LDSILSHTTRTFTIHAVSREHEGL 227
V V++ T PP TW L L + ++ + H G
Sbjct: 1076 QVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGR 1135
Query: 228 YRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARS-----VDLTCQTVN-Q 281
Y C+ N A L V V P + L+ + N + + L C+ +
Sbjct: 1136 YSCVAENLAGRAERKFELSVLV------PPELIGDLDPLTNITAALHSPLTLLCEAMGIP 1189
Query: 282 SVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELT 341
++WF +P+ P E L A L + Q D+G Y+C N AR +
Sbjct: 1190 PPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRN-FSVE 1248
Query: 342 INYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW-----TLEHSTGEH 396
+ P I E E+I ++ + + L C P + W L H
Sbjct: 1249 VLVPPS---IENEDLEEVIKVLDGQ---TAHLMCNVTGHPQPKLTWFKDGRPLARGDAHH 1302
Query: 397 L---GEQLIIRALTWEHDGIYNCTASNSL 422
+ G L + G Y+C A+N++
Sbjct: 1303 ISPDGVLLQVLQANLSSAGHYSCIAANAV 1331
Score = 50.1 bits (118), Expect = 6e-06
Identities = 75/323 (23%), Positives = 116/323 (35%), Gaps = 40/323 (12%)
Query: 115 QLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASG 174
Q + G L + V DSGTY C A R F P +E SG
Sbjct: 2259 QSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH--FQLTVMEPPHIE-------DSG 2309
Query: 175 EVVEVM--EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHE-GLYRCL 231
+ E+ G+ M L + + P TW L+ V R + GLY CL
Sbjct: 2310 QPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCL 2369
Query: 232 VSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSG 291
+ A + ++V+ + P+ + L ++ + + + + W G
Sbjct: 2370 AESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEA-EPAPKITWHRDG 2428
Query: 292 QPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN-WGSRARSEPLEL----TINYGP 346
L H Q R L + L D+G Y+C N GS + + +E+ TI GP
Sbjct: 2429 IVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGP 2488
Query: 347 DQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEH-------STGEHLGE 399
V+++ +N + L C A+ P W + E L E
Sbjct: 2489 PAVNVS--------------VNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPE 2534
Query: 400 -QLIIRALTWEHDGIYNCTASNS 421
L I+ + + G Y C ASNS
Sbjct: 2535 GSLRIQPVLAQDAGHYLCLASNS 2557
Score = 48.9 bits (115), Expect = 1e-05
Identities = 75/302 (24%), Positives = 113/302 (37%), Gaps = 36/302 (11%)
Query: 133 SGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETK 192
+G Y C AR++ +FL V+ PV L S VV + + E
Sbjct: 2731 AGRYTCSARNSA-GVAHKHVFLTVQ--ASPVVKPLPS------VVRAVAEEEVLLPCEAS 2781
Query: 193 SHPPCAYTWFL--LDSILSHTTRTFT-----IHAVSREHEGLYRCLVSNSATHLSSLGTL 245
P TW L+ +T+ I S E G Y C+ NSA S++G
Sbjct: 2782 GIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG--SAMGKT 2839
Query: 246 KVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQ-SVNVQWFLSGQPLLPSEHLQLSA 304
++ V + +P L+ E + + L C+ N+ W GQP+ +E
Sbjct: 2840 RLVVQVPPVIENGLPD-LSTTEGSHAF-LPCKARGSPEPNITWDKDGQPVSGAEGKFTIQ 2897
Query: 305 DNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIE 364
+ L++ L+ D G Y C N RAR + LTI P + + +
Sbjct: 2898 PSGELLVKNLEGQDAGTYTCTAENAVGRARRR-VHLTILVLPVFTTLPGDRS-------- 2948
Query: 365 AELNSSLTLQCWAESKPGAEYRWTL------EHSTGEHLGEQLIIRALTWEHDGIYNCTA 418
L L L+C A P WT+ E + + G L A++ E G Y C A
Sbjct: 2949 LRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWA 3008
Query: 419 SN 420
N
Sbjct: 3009 EN 3010
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/175 (26%), Positives = 72/175 (41%), Gaps = 19/175 (10%)
Query: 272 VDLTCQTVN-QSVNVQWFLSGQPLLPS-EHLQLSADNRTLIIHGLQRNDTGPYACEVWN- 328
V+L C T + V+W QP+LP HLQ+ D + L I G D G Y C ++
Sbjct: 235 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSP 294
Query: 329 WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW- 387
G +AR L + + P + + E+ ++ +E L + L C A P W
Sbjct: 295 AGQQARDFQLRV---HAPPTIWGSNETGE--VAVMEDHL---VQLLCEARGVPTPNITWF 346
Query: 388 -------TLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
T G QL + G+Y C ASN++ ++T + V V
Sbjct: 347 KDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV 401
Score = 42.0 bits (97), Expect = 0.002
Identities = 90/371 (24%), Positives = 132/371 (35%), Gaps = 52/371 (14%)
Query: 99 IHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
I W + + + Q + G+ L + + DSG Y C AR+A S V +
Sbjct: 2422 ITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGST-------SVAF 2474
Query: 159 GPDPVEIKLESGVASGE-VVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTI 217
VEI + SG V V + + P +W L + F I
Sbjct: 2475 R---VEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEI 2531
Query: 218 --------HAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENA 269
V + G Y CL SNSA + R L L P + PS NL A
Sbjct: 2532 LPEGSLRIQPVLAQDAGHYLCLASNSAG-----SDRQGRDLRVLEPPAIAPSPSNLTLTA 2586
Query: 270 RSVDLTCQTVNQSVN--VQWFLSGQPLLPSEHLQLSA----DNRTLIIHGLQRNDTGPYA 323
+ L + S V W+ GQ L LQ A + L++ D+ +
Sbjct: 2587 HTPALLPCEASGSPKPLVVWWKDGQKL--DFRLQQGAYRLLPSNALLLTAPGPQDSAQFE 2644
Query: 324 CEVWNWGSRARSEPLELTINYGP----DQVHITRESASEMISTIEAELNSSLTLQCWAES 379
C V N A ++T++ P DQ T + ++ T + + T+ W S
Sbjct: 2645 CVVSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS-W--S 2700
Query: 380 KPGAEY-----RWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVK 434
K GA+ + + S +G+ L I H G Y C+A NS G+A L
Sbjct: 2701 KAGAQLGARGSGYRVSPSGALEIGQALPI------HAGRYTCSARNS-AGVAHKHVFLTV 2753
Query: 435 VVGPQSSSLSS 445
P L S
Sbjct: 2754 QASPVVKPLPS 2764
Score = 34.7 bits (78), Expect = 0.26
Identities = 60/238 (25%), Positives = 85/238 (35%), Gaps = 42/238 (17%)
Query: 224 HEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVV---PSSLNLVENARSVDLTCQTVN 280
H G Y C NSA G V T+ VV PS + V V L C+
Sbjct: 2730 HAGRYTCSARNSA------GVAHKHVFLTVQASPVVKPLPSVVRAVAE-EEVLLPCEASG 2782
Query: 281 -QSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLE 339
+ W G + Q+ + I H D G Y C N A +
Sbjct: 2783 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHA-SPEDAGNYLCIAKNSAGSAMGKTRL 2841
Query: 340 LTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKP--------------GAEY 385
+ QV E+ +ST E S L C A P GAE
Sbjct: 2842 VV------QVPPVIENGLPDLSTTEG---SHAFLPCKARGSPEPNITWDKDGQPVSGAEG 2892
Query: 386 RWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSL 443
++T++ S +L+++ L + G Y CTA N++ G AR L +V P ++L
Sbjct: 2893 KFTIQPSG------ELLVKNLEGQDAGTYTCTAENAV-GRARRRVHLTILVLPVFTTL 2943
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 87.4 bits (215), Expect = 3e-17
Identities = 97/358 (27%), Positives = 138/358 (38%), Gaps = 48/358 (13%)
Query: 98 TIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSD------- 150
TI W + V R+Q+ +G++L I Q DSG Y C A + D
Sbjct: 2670 TIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQV 2729
Query: 151 -PIFLDVKYGPDPVEIKLESGVASGEVVE---VMEGSSMTFLAETKSHPPCAYTWFLLDS 206
P+F V EI A G V E ++E + +T + PP TW+ D
Sbjct: 2730 PPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQ 2789
Query: 207 ILS--------HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQV 258
LS R I V E+ G Y C SN L +L LT P +
Sbjct: 2790 PLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGE----DWLHYELL-VLTPPVI 2844
Query: 259 VPSSLNLVE----NARS-VDLTCQTVNQSV-NVQWFLSGQPLLPSEHLQLSADNRTLIIH 312
+ + LVE NA S V L C + V + W +G P PS LQ+ D + L +
Sbjct: 2845 LGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVS 2904
Query: 313 GLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT 372
+ D Y C N +A S T+ +V + A + + A LNSS++
Sbjct: 2905 TAEVADAASYMCVAEN---QAGSAEKLFTL-----RVQVPPRIAGLDLEQVTAILNSSVS 2956
Query: 373 LQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALT---------WEHDGIYNCTASNS 421
L C + P E W + S LGE++ + T G+Y C A N+
Sbjct: 2957 LPCDVHAHPNPEVTW-YKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNA 3013
Score = 84.0 bits (206), Expect = 4e-16
Identities = 91/363 (25%), Positives = 139/363 (38%), Gaps = 36/363 (9%)
Query: 98 TIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF-LDV 156
TI W+ N L R+Q+ +DG++L + + D+ +Y C A + S ++ +F L V
Sbjct: 2876 TISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGS--AEKLFTLRV 2933
Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILS------- 209
+ P + LE V + SS++ + +HP TW+ LS
Sbjct: 2934 QVPPRIAGLDLEQ-------VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFL 2986
Query: 210 -HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268
T T + G+Y C N+A L L V V P LV
Sbjct: 2987 LPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRV 3046
Query: 269 ARSVDLTCQT-VNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVW 327
L+C+T V W+ GQPL+ ++ Q + L I Q +D G Y+C+V
Sbjct: 3047 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVS 3106
Query: 328 NWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW 387
N A LT+ P + E+ S++ S L L C P W
Sbjct: 3107 NVAGEA-VRTFTLTVQVPPTFENPKTETVSQV-------AGSPLVLTCDVSGVPAPTVTW 3158
Query: 388 TLE----HSTGEH----LGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQ 439
+ S+ H G +L + L G Y C A N+ AR V+ +V P+
Sbjct: 3159 LKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENT-QAEARKDFVVAVLVAPR 3217
Query: 440 SSS 442
S
Sbjct: 3218 IRS 3220
Score = 72.8 bits (177), Expect = 8e-13
Identities = 86/361 (23%), Positives = 141/361 (39%), Gaps = 39/361 (10%)
Query: 99 IHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
I W V E L G +L + Q +DSG Y C A + R + ++V
Sbjct: 2384 IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRN-FSVEVLV 2442
Query: 159 GPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWF-----LLDSILSHTTR 213
P LE EV++V++G + + HP TWF L H +
Sbjct: 2443 PPSIENEDLE------EVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISP 2496
Query: 214 TFTIHAVSREH---EGLYRCLVSNSATHLSSLGTLKVRVLETL------TMPQVVPSSLN 264
+ V + + G Y C+ +N+ + L V + T+ + + V ++N
Sbjct: 2497 DGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVN 2556
Query: 265 LVENARSVDLTCQTVN-QSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYA 323
+ L C+ + S N+ W G P S ++QL L I Q+ D G Y
Sbjct: 2557 -----NPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYT 2611
Query: 324 CEVWN-WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPG 382
C V N G ++ +E+ I P + + ++ ++NS+LTL+C + + P
Sbjct: 2612 CVVTNELGEAVKNYHVEVLI---PPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPP 2668
Query: 383 AEYRW------TLEHSTGEHLGE--QLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVK 434
RW S + LGE L I+ G Y C A+N + +VL++
Sbjct: 2669 PTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ 2728
Query: 435 V 435
V
Sbjct: 2729 V 2729
Score = 69.7 bits (169), Expect = 7e-12
Identities = 96/366 (26%), Positives = 141/366 (38%), Gaps = 46/366 (12%)
Query: 98 TIHWVS--NNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLD 155
T+ W+ N +S +Q+ G++LT+ + DSG Y C A A+ R D + L
Sbjct: 2008 TLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD-VVLQ 2066
Query: 156 VKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSH--PPCAYTWFLLDSILS---- 209
V P + +L V + E V + E +SH PP +W+ L
Sbjct: 2067 VHMPPSILGEELNVSVVANESVAL----------ECQSHAMPPPVLSWWKDGRPLEPRPG 2116
Query: 210 -HTTRTFTIHAVSRE---HEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNL 265
H + + V R G Y C N A H L V V + + S
Sbjct: 2117 VHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRE---SHTLT 2173
Query: 266 VENARSVDLTCQTVNQSV-NVQWFLSGQPLLPSEHLQL---SADNRTLIIHGLQRNDTGP 321
V L+C+ + W GQP LP E L SA R L + Q G
Sbjct: 2174 VREGHPTSLSCECRGVPFPKISWRKDGQP-LPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 2232
Query: 322 YACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKP 381
Y CE N + S+ L+L ++ P Q+ RE ++ +S ++ + TL+C A KP
Sbjct: 2233 YTCECSNVVGNS-SQDLQLEVHV-PPQIAGPREPPTQ-VSVVQ---DGVATLECNATGKP 2286
Query: 382 GAEYRWTLE-HSTGEHL-------GEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLV 433
W + G L G+ L + H G Y+C A N L G A L
Sbjct: 2287 PPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN-LAGRAERKFELS 2345
Query: 434 KVVGPQ 439
+V P+
Sbjct: 2346 VLVPPE 2351
Score = 66.6 bits (161), Expect = 6e-11
Identities = 82/318 (25%), Positives = 122/318 (38%), Gaps = 42/318 (13%)
Query: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182
L I V D G Y C A + L + + L V P+ +E G + V +E
Sbjct: 1850 LQIEKVDLRDEGIYTCAATN-LAGESKREVALKVLVPPN-----IEPGPVNKAV---LEN 1900
Query: 183 SSMTFLAETKSHPPCAYTWFL--------LDSILSHTTRTFTIHAVSREHEGLYRCLVSN 234
+S+T PP +WF + +S R I G YRC+ SN
Sbjct: 1901 ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 1960
Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQ-TVNQSVNVQWFLSGQP 293
A L+V V +T+P +P + LV V LTC T S + W G P
Sbjct: 1961 VAGSTELRYGLRVNVPPRITLPPSLPGPV-LVNT--PVRLTCNATGAPSPTLMWLKDGNP 2017
Query: 294 LLP--SEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHI 351
+ P + LQ+ R L + + +D+G Y+C + R + + QVH+
Sbjct: 2018 VSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL--------QVHM 2069
Query: 352 TRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW-----TLEHSTGEHLGEQLII--- 403
E ++ + N S+ L+C + + P W LE G HL +
Sbjct: 2070 PPSILGEELN-VSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQV 2128
Query: 404 -RALTWEHDGIYNCTASN 420
RA W+ G Y C A N
Sbjct: 2129 DRADVWD-AGHYTCEALN 2145
Score = 66.6 bits (161), Expect = 6e-11
Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 23/238 (9%)
Query: 99 IHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
I W N+ V E + G L V REDSGTY C A + + + F+ VK
Sbjct: 4160 IGWTVNDRPVT--EGVSEQDGGSTLQRAAVSREDSGTYVCWAENR-VGRTQAVSFVHVKE 4216
Query: 159 GPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWF-----LLDSILSHTTR 213
P + G A +VE + G S+ + P W L S L H +
Sbjct: 4217 AP------VLQGEAFSYLVEPV-GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ 4269
Query: 214 --TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARS 271
+ TIH R+ G Y+CL N + + + VL++ + QV P + V +
Sbjct: 4270 NGSLTIHRTERDDAGRYQCLAEN---EMGVAKKVVILVLQSAPVFQVEPQDMT-VRSGDD 4325
Query: 272 VDLTCQTVNQ-SVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
V L CQ + + ++W +GQPL S L+ D +L + ++ D G Y C N
Sbjct: 4326 VALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG-SLWLENVETGDAGTYDCVAHN 4382
Score = 65.1 bits (157), Expect = 2e-10
Identities = 77/324 (23%), Positives = 115/324 (35%), Gaps = 32/324 (9%)
Query: 114 MQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVAS 173
+Q+ +DG++L I D G YQC A Q D F + P + E+G
Sbjct: 1456 LQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARD--FQLRVHAPPTIWGSNETG--- 1510
Query: 174 GEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTT--------RTFTIHAVSREHE 225
V VME + L E + P TWF ++L +T R +
Sbjct: 1511 --EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDA 1568
Query: 226 GLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVN 284
G+Y C SN+ L V V T+ P + V R V L C + S
Sbjct: 1569 GVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVA-GRPVALECVARGHPSPT 1627
Query: 285 VQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINY 344
+ W G P+ S +L D L + +G Y+C A S E + Y
Sbjct: 1628 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCV-------ASSPAGEAVLQY 1680
Query: 345 GPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHL------- 397
+ + +E + + + L L C A P +W E L
Sbjct: 1681 SVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVAS 1740
Query: 398 -GEQLIIRALTWEHDGIYNCTASN 420
G L I + +H G++ C A+N
Sbjct: 1741 QGTTLHIDHVELDHSGLFACQATN 1764
Score = 63.9 bits (154), Expect = 4e-10
Identities = 88/386 (22%), Positives = 157/386 (40%), Gaps = 38/386 (9%)
Query: 79 AIEQKDMVTFYCTTKDV---NITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGT 135
A+ + +V C + V NIT W + + ++ ++ G+ L + Q D+G
Sbjct: 1513 AVMEDHLVQLLCEARGVPTPNIT--WFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGV 1570
Query: 136 YQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHP 195
Y C+A +A+ LDV P +E VV+ + G + + HP
Sbjct: 1571 YTCKASNAV-GAAEKATRLDVYVPPT-----IEGAGGRPYVVKAVAGRPVALECVARGHP 1624
Query: 196 PCAYTWFL--LDSILSHTTRTFTIHAVSR------EHEGLYRCLVSNSATHLSSLGTLKV 247
+W L S+ +R T +V R GLY C+ S+ A +++V
Sbjct: 1625 SPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEV 1684
Query: 248 RVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSV-NVQWFLSGQPLLPSEHLQLSADN 306
+V L + + + +V + ++L CQ V +QW +G+P +Q+++
Sbjct: 1685 QVPPQLLVAEGLGQVTTIV--GQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQG 1742
Query: 307 RTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN--YGPDQVHI---TRESASEMIS 361
TL I ++ + +G +AC+ N A +E +E++++ + P + + E S
Sbjct: 1743 TTLHIDHVELDHSGLFACQATNEAGTAGAE-VEVSVHGEWAPGVLEVPIGQYHWGXEHHS 1801
Query: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST-GEHLG--------EQLIIRALTWEHDG 412
+ A + + A KP W S GE G L I + +G
Sbjct: 1802 SFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEG 1861
Query: 413 IYNCTASNSLTGLARSTSVLVKVVGP 438
IY C A+N L G ++ L +V P
Sbjct: 1862 IYTCAATN-LAGESKREVALKVLVPP 1886
Score = 62.8 bits (151), Expect = 9e-10
Identities = 81/366 (22%), Positives = 144/366 (39%), Gaps = 45/366 (12%)
Query: 96 NITIH------WVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRS 149
N+T H W + + + +S DG +L +L +G Y C A +A+ +++
Sbjct: 2468 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAV-GEKT 2526
Query: 150 DPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILS 209
L V P + +S + E V V + ++ + E + P TW + D
Sbjct: 2527 KHFQLSVLLAPTILGGAEDS---ADEEVTVTVNNPISLICEALAFPSPNITW-MKDGAPF 2582
Query: 210 HTTRTFTI----HAVS-----REHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVP 260
+R + H + +E G Y C+V+N ++V + +++ +
Sbjct: 2583 EASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLG 2642
Query: 261 S-SLNLVENARSVDLTCQTVNQSV---NVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQR 316
+ V+ + LT + + +V ++W+ GQP+ PS LQ+ + R L I Q
Sbjct: 2643 EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQV 2702
Query: 317 NDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT---- 372
+D+G Y C N + + I P + SA+ I + E E +T
Sbjct: 2703 SDSGRYLCVATNVAGE-DDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYRE 2761
Query: 373 --------LQCWAESKPGAEYRWTLEH---STGEHL-----GEQLIIRALTWEHDGIYNC 416
L C + P + W E S G+ + G L I + E+ G Y+C
Sbjct: 2762 IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSC 2821
Query: 417 TASNSL 422
ASN +
Sbjct: 2822 KASNEV 2827
Score = 62.0 bits (149), Expect = 1e-09
Identities = 90/367 (24%), Positives = 129/367 (35%), Gaps = 50/367 (13%)
Query: 96 NITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEA-----RDALLSQRS- 149
N + W ++ ++ E + L L + + DSG Y CEA RD L Q S
Sbjct: 2966 NPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSV 3025
Query: 150 --DPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI 207
P F GP + V V G ET + P TW+
Sbjct: 3026 LVPPAFRQAPRGPQ-------------DAVLVRVGDKAVLSCETDALPEPTVTWYKDGQP 3072
Query: 208 LSHTTRTFTIHAVSR--------EHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVV 259
L RT + R +GLY C VSN A TL V+V T P+
Sbjct: 3073 LVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKT- 3131
Query: 260 PSSLNLVENARSVDLTCQTVN-QSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRND 318
+++ V + V LTC + V W P+ S + + L + LQ
Sbjct: 3132 -ETVSQVAGSPLV-LTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQ 3189
Query: 319 TGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAE 378
G Y C N + AR + + + P I + +E + + L C A+
Sbjct: 3190 AGTYTCVAENTQAEARKD-FVVAVLVAP---RIRSSGVAREHHVLEGQ---EVRLDCEAD 3242
Query: 379 SKPGAEYRW-----TLEHSTGEHL-----GEQLIIRALTWEHDGIYNCTASNSLTGLARS 428
+P + W L G HL G L+++ L G Y C A N AR
Sbjct: 3243 GQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARL 3302
Query: 429 TSVLVKV 435
+V V V
Sbjct: 3303 HTVNVLV 3309
Score = 61.6 bits (148), Expect = 2e-09
Identities = 90/414 (21%), Positives = 149/414 (35%), Gaps = 65/414 (15%)
Query: 62 GRSRELAKPSIAVSPG-----------TAIEQKDMVTFYCTTKDV-NITIHWVSNNLSVV 109
GR ++L + S+ V P + D C T + T+ W + +V
Sbjct: 3015 GRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLV 3074
Query: 110 FHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLES 169
+R Q + G+ L I Q D G Y C+ + + + L V+ P K E+
Sbjct: 3075 LAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSN-VAGEAVRTFTLTVQVPPTFENPKTET 3133
Query: 170 GVASGEVVEVMEGSSMTFLAETKSHPPCAYTWF---------LLDSILSHTTRTFTIHAV 220
V + GS + + P TW + ++S R + +
Sbjct: 3134 -------VSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGR-LQLSRL 3185
Query: 221 SREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSL---NLVENARSVDLTCQ 277
G Y C+ N+ K V+ L P++ S + + V + V L C+
Sbjct: 3186 QPAQAGTYTCVAENTQAEAR-----KDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCE 3240
Query: 278 TVNQSV-NVQWFLSGQPLLPS--EHLQLSADNRTLIIHGLQRNDTGPYACEVWN-WGSRA 333
Q +V W G PL HL+ D +L++ GL+ +D G Y C N G A
Sbjct: 3241 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDA 3300
Query: 334 RSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW------ 387
R T+N V T + ++ T+ + +T+ C P W
Sbjct: 3301 RLH----TVNV---LVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLP 3353
Query: 388 ------TLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
TL H + G L I + GI+ C A++ R+ ++ V+V
Sbjct: 3354 LPLSQRTLLHGS----GHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQV 3403
Score = 60.1 bits (144), Expect = 6e-09
Identities = 89/364 (24%), Positives = 139/364 (38%), Gaps = 55/364 (15%)
Query: 99 IHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
I W + ++ R+ + G ++ I V ED+G Y C+A + + + + Y
Sbjct: 639 ISWSRESQALQEDSRIHVDAQGTLI-IQGVAPEDAGNYSCQATNEVGTDQETVTL----Y 693
Query: 159 GPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFL--LDSILS---HTTR 213
DP + A VV V G + E PP W+ L+ IL+ ++
Sbjct: 694 YTDPPSVS-----AVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSG 748
Query: 214 TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLT-MPQVVPSSLNLVENARSV 272
I A G Y C N S+ L V LT +P+ V VE RS
Sbjct: 749 KLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVT-----VELGRSA 803
Query: 273 DLTCQTVNQSV-NVQWFLS-GQPLLPSEHLQLSA---------DNRTLIIHGLQRNDTGP 321
L C+ + V W GQPL L+L A D+ L + D P
Sbjct: 804 LLACRATGRPPPTVTWRRGDGQPL----GLRLGAGRGSRSRQPDSGVLFFESVAPEDQAP 859
Query: 322 YACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWA-ESK 380
Y CE N + ++E + + P Q+ S++ + +E + ++L C +
Sbjct: 860 YVCEARNVFGKVQAEARLIVTGHAPPQI----ASSAPTVRVLEGQ---PVSLPCIVLAGR 912
Query: 381 PGAEYRWTLE---------HSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSV 431
P E W + HS G + RAL EH G Y+C A+N+ R +
Sbjct: 913 PLPERHWLKDGRPLPPGSRHSIRAD-GSLHLDRALQ-EHAGRYSCVATNTAGSQHRDVEL 970
Query: 432 LVKV 435
+V+V
Sbjct: 971 VVQV 974
Score = 60.1 bits (144), Expect = 6e-09
Identities = 106/471 (22%), Positives = 168/471 (35%), Gaps = 61/471 (12%)
Query: 7 WGHHWMGILLSA--SLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRS 64
WG H L+ S ++W P + + P + D+ T + G S
Sbjct: 1815 WGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGES 1874
Query: 65 RE------LAKPSIAVSP-GTAIEQKDMVTFYCTTKDVNIT-IHWVSNNLSVVFHERMQL 116
+ L P+I P A+ + VT C V + W + V + +
Sbjct: 1875 KREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTV 1934
Query: 117 SKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYG---PDPVEIKLESGVAS 173
S DG++L I Q D+G+Y+C A + S +++YG P I L +
Sbjct: 1935 SVDGRVLRIEQAQLSDAGSYRCVASNVAGS-------TELRYGLRVNVPPRITLPPSLPG 1987
Query: 174 GEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHT----------TRTFTIHAVSRE 223
V+ + + P W + +S R T+ +
Sbjct: 1988 ----PVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARAS 2043
Query: 224 HEGLYRCLVSNSATHLSSLGTLKVRVLETLTM-PQVVPSSLNL-VENARSVDLTCQTVNQ 281
G Y C+ +S++G + V+ + M P ++ LN+ V SV L CQ+
Sbjct: 2044 DSGRYSCVA------VSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAM 2097
Query: 282 SVNV-QWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLEL 340
V W+ G+PL P + LSAD L + D G Y CE N +A
Sbjct: 2098 PPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALN---QAGHSEKHY 2154
Query: 341 TINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQ 400
+N V RES + T+ +SL+ +C P +R + GE G Q
Sbjct: 2155 NLNVWVAPVFPLRESHT---LTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQ 2211
Query: 401 --------LIIRALTWEHDGIYNCTAS----NSLTGLARSTSVLVKVVGPQ 439
L + +G Y C S NS L V ++ GP+
Sbjct: 2212 HVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPR 2262
Score = 53.9 bits (128), Expect = 4e-07
Identities = 58/254 (22%), Positives = 104/254 (40%), Gaps = 24/254 (9%)
Query: 214 TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVD 273
++ I S+ EG Y C +A + G K +++ T PQ+VP+ V +
Sbjct: 480 SWEILRASKAEEGTYEC----TAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAV 535
Query: 274 LTCQTVNQS-VNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSR 332
L+C+ + ++ N+ W + L S + +L I G+ D G Y C N
Sbjct: 536 LSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGV 595
Query: 333 ARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWT---- 388
R+ L +H + + S+ + + + C A P W+
Sbjct: 596 TRASVWLLVREAPQVSIHTSSQHFSQGV---------EVKVSCSASGYPTPHISWSRESQ 646
Query: 389 -LEHSTGEHLGEQ--LIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSS 445
L+ + H+ Q LII+ + E G Y+C A+N + G + T L P S+++
Sbjct: 647 ALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEV-GTDQETVTLYYTDPPSVSAVN- 704
Query: 446 GAIAGIVIGILAVI 459
A+ + +G AV+
Sbjct: 705 -AVVLVAVGEEAVL 717
Score = 52.4 bits (124), Expect = 1e-06
Identities = 82/354 (23%), Positives = 129/354 (36%), Gaps = 56/354 (15%)
Query: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182
L + ++ +D+GTY C A +A+ R + L + P + + + G+
Sbjct: 4093 LLVKNLEGQDAGTYTCTAENAVGRARRR-VHLTILVLPVFTTLPGDRSLRLGD------- 4144
Query: 183 SSMTFLAETKSHPPCAYTWFLLDSILSHTTR------TFTIHAVSREHEGLYRCLVSNSA 236
+ + P W + D ++ T AVSRE G Y C N
Sbjct: 4145 -RLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRV 4203
Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSV-NVQWFLSGQPLL 295
++ + V+ L Q S + S+ L C V ++ W G PL
Sbjct: 4204 GRTQAVSFVHVKEAPVL---QGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR 4260
Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARS--------------EPLELT 341
S HL+ N +L IH +R+D G Y C N A+ EP ++T
Sbjct: 4261 GS-HLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMT 4319
Query: 342 INYGPDQVHITRESASEMISTIE-AELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQ 400
+ G D V + ++ E TIE + L + P W TG+
Sbjct: 4320 VRSG-DDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSL-WLENVETGD----- 4372
Query: 401 LIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIG 454
G Y+C A N L G A + + LV PQ S G++ G++ G
Sbjct: 4373 ----------AGTYDCVAHN-LLGSATARAFLVVRGEPQG---SWGSMTGVING 4412
Score = 51.2 bits (121), Expect = 3e-06
Identities = 70/329 (21%), Positives = 116/329 (35%), Gaps = 41/329 (12%)
Query: 116 LSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGE 175
+S G++L + Q GTY CE + ++ S + L+V P ++
Sbjct: 2213 VSAVGRLLYLGQAQLAQEGTYTCECSN-VVGNSSQDLQLEVHVPP-----QIAGPREPPT 2266
Query: 176 VVEVMEGSSMTFLAETKSHPPCAYTWFL--------LDSILSHTTRTFTIHAVSREHEGL 227
V V++ T PP TW L L + ++ + H G
Sbjct: 2267 QVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGR 2326
Query: 228 YRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARS-----VDLTCQTVN-Q 281
Y C+ N A L V V P + L+ + N + + L C+ +
Sbjct: 2327 YSCVAENLAGRAERKFELSVLV------PPELIGDLDPLTNITAALHSPLTLLCEAMGIP 2380
Query: 282 SVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELT 341
++WF +P+ P E L A L + Q D+G Y+C N AR +
Sbjct: 2381 PPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRN-FSVE 2439
Query: 342 INYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW-----TLEHSTGEH 396
+ P I E E+I ++ + + L C P + W L H
Sbjct: 2440 VLVPPS---IENEDLEEVIKVLDGQ---TAHLMCNVTGHPQPKLTWFKDGRPLARGDAHH 2493
Query: 397 L---GEQLIIRALTWEHDGIYNCTASNSL 422
+ G L + G Y+C A+N++
Sbjct: 2494 ISPDGVLLQVLQANLSSAGHYSCIAANAV 2522
Score = 50.1 bits (118), Expect = 6e-06
Identities = 75/323 (23%), Positives = 116/323 (35%), Gaps = 40/323 (12%)
Query: 115 QLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASG 174
Q + G L + V DSGTY C A R F P +E SG
Sbjct: 3450 QSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH--FQLTVMEPPHIE-------DSG 3500
Query: 175 EVVEVM--EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHE-GLYRCL 231
+ E+ G+ M L + + P TW L+ V R + GLY CL
Sbjct: 3501 QPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCL 3560
Query: 232 VSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSG 291
+ A + ++V+ + P+ + L ++ + + + + W G
Sbjct: 3561 AESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEA-EPAPKITWHRDG 3619
Query: 292 QPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN-WGSRARSEPLEL----TINYGP 346
L H Q R L + L D+G Y+C N GS + + +E+ TI GP
Sbjct: 3620 IVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGP 3679
Query: 347 DQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEH-------STGEHLGE 399
V+++ +N + L C A+ P W + E L E
Sbjct: 3680 PAVNVS--------------VNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPE 3725
Query: 400 -QLIIRALTWEHDGIYNCTASNS 421
L I+ + + G Y C ASNS
Sbjct: 3726 GSLRIQPVLAQDAGHYLCLASNS 3748
Score = 48.9 bits (115), Expect = 1e-05
Identities = 75/302 (24%), Positives = 113/302 (37%), Gaps = 36/302 (11%)
Query: 133 SGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETK 192
+G Y C AR++ +FL V+ PV L S VV + + E
Sbjct: 3922 AGRYTCSARNSA-GVAHKHVFLTVQ--ASPVVKPLPS------VVRAVAEEEVLLPCEAS 3972
Query: 193 SHPPCAYTWFL--LDSILSHTTRTFT-----IHAVSREHEGLYRCLVSNSATHLSSLGTL 245
P TW L+ +T+ I S E G Y C+ NSA S++G
Sbjct: 3973 GIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG--SAMGKT 4030
Query: 246 KVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQ-SVNVQWFLSGQPLLPSEHLQLSA 304
++ V + +P L+ E + + L C+ N+ W GQP+ +E
Sbjct: 4031 RLVVQVPPVIENGLPD-LSTTEGSHAF-LPCKARGSPEPNITWDKDGQPVSGAEGKFTIQ 4088
Query: 305 DNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIE 364
+ L++ L+ D G Y C N RAR + LTI P + + +
Sbjct: 4089 PSGELLVKNLEGQDAGTYTCTAENAVGRARRR-VHLTILVLPVFTTLPGDRS-------- 4139
Query: 365 AELNSSLTLQCWAESKPGAEYRWTL------EHSTGEHLGEQLIIRALTWEHDGIYNCTA 418
L L L+C A P WT+ E + + G L A++ E G Y C A
Sbjct: 4140 LRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWA 4199
Query: 419 SN 420
N
Sbjct: 4200 EN 4201
Score = 48.5 bits (114), Expect = 2e-05
Identities = 82/351 (23%), Positives = 122/351 (34%), Gaps = 59/351 (16%)
Query: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182
L + V DSG Y+C+A + + S V Y P + SG M G
Sbjct: 1263 LFLASVSPADSGDYECQATNEVGSTSRRAKL--VVYVPPSIREDGRKANVSG-----MAG 1315
Query: 183 SSMTFLAETKSHPPCAYTWFLLDSI-----------------------LSHTTRTFTIHA 219
S+T + P W + L ++
Sbjct: 1316 QSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPR 1375
Query: 220 VSREHEGLYRCLVSNSATHLSSLGTLKVRV-LETLTMPQVVPSSLN---LVENARSVDLT 275
+ GLY C N A GT + L LT P V+ + L V+L
Sbjct: 1376 IQEGDSGLYSCRAENQA------GTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQ 1429
Query: 276 CQTVN-QSVNVQWFLSGQPLLPS-EHLQLSADNRTLIIHGLQRNDTGPYACEVWN-WGSR 332
C T + V+W QP+LP HLQ+ D + L I G D G Y C ++ G +
Sbjct: 1430 CWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQ 1489
Query: 333 ARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW----- 387
AR L + + P + + E+ ++ +E L + L C A P W
Sbjct: 1490 ARDFQLRV---HAPPTIWGSNETGE--VAVMEDHL---VQLLCEARGVPTPNITWFKDGA 1541
Query: 388 ---TLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
T G QL + G+Y C ASN++ ++T + V V
Sbjct: 1542 LLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV 1592
Score = 42.4 bits (98), Expect = 0.001
Identities = 87/362 (24%), Positives = 138/362 (38%), Gaps = 53/362 (14%)
Query: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182
L + VQ DSG Y+C A + S S L V+ P +++ G V++V+ G
Sbjct: 1084 LRLAQVQVGDSGHYECTASNPAGSA-SHRYVLGVQVPP-----QVQPGP---RVLKVLVG 1134
Query: 183 SSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIH--AVSREHEGLYRCLVSNSATHLS 240
++ + +P +W +L ++H A+ G YRC SNSA
Sbjct: 1135 EALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRTSDAGRYRCEASNSAG--V 1192
Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQ---TVNQSVNVQWFLSGQPLLPS 297
+++RVLE S L + L C T V + S +PL
Sbjct: 1193 DAWEVELRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQ 1252
Query: 298 EHLQLSADNRTLIIHGLQRNDTGPYACEVWN-WGSRARSEPLELTINYGPDQVHITRESA 356
+ + + +L + + D+G Y C+ N GS +R L + Y P + RE
Sbjct: 1253 PGVAV-LEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKL---VVYVPPSI---REDG 1305
Query: 357 SEMISTIEAELNSSLTLQCWAESKPGAEYRWTLE-------------------HSTGEHL 397
+ + + SLTL+C A P E W + G H
Sbjct: 1306 RK--ANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHR 1363
Query: 398 ----GEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVI 453
G+ L + G+Y+C A N G A+ L+ + P S L +GA A V+
Sbjct: 1364 LLDEGQSLHFPRIQEGDSGLYSCRAENQ-AGTAQRDFHLLVLTPP--SVLGAGA-AQEVL 1419
Query: 454 GI 455
G+
Sbjct: 1420 GL 1421
Score = 42.0 bits (97), Expect = 0.002
Identities = 90/371 (24%), Positives = 132/371 (35%), Gaps = 52/371 (14%)
Query: 99 IHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
I W + + + Q + G+ L + + DSG Y C AR+A S V +
Sbjct: 3613 ITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGST-------SVAF 3665
Query: 159 GPDPVEIKLESGVASGE-VVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTI 217
VEI + SG V V + + P +W L + F I
Sbjct: 3666 R---VEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEI 3722
Query: 218 --------HAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENA 269
V + G Y CL SNSA + R L L P + PS NL A
Sbjct: 3723 LPEGSLRIQPVLAQDAGHYLCLASNSAG-----SDRQGRDLRVLEPPAIAPSPSNLTLTA 3777
Query: 270 RSVDLTCQTVNQSVN--VQWFLSGQPLLPSEHLQLSA----DNRTLIIHGLQRNDTGPYA 323
+ L + S V W+ GQ L LQ A + L++ D+ +
Sbjct: 3778 HTPALLPCEASGSPKPLVVWWKDGQKL--DFRLQQGAYRLLPSNALLLTAPGPQDSAQFE 3835
Query: 324 CEVWNWGSRARSEPLELTINYGP----DQVHITRESASEMISTIEAELNSSLTLQCWAES 379
C V N A ++T++ P DQ T + ++ T + + T+ W S
Sbjct: 3836 CVVSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS-W--S 3891
Query: 380 KPGAEY-----RWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVK 434
K GA+ + + S +G+ L I H G Y C+A NS G+A L
Sbjct: 3892 KAGAQLGARGSGYRVSPSGALEIGQALPI------HAGRYTCSARNS-AGVAHKHVFLTV 3944
Query: 435 VVGPQSSSLSS 445
P L S
Sbjct: 3945 QASPVVKPLPS 3955
Score = 34.7 bits (78), Expect = 0.26
Identities = 60/238 (25%), Positives = 85/238 (35%), Gaps = 42/238 (17%)
Query: 224 HEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVV---PSSLNLVENARSVDLTCQTVN 280
H G Y C NSA G V T+ VV PS + V V L C+
Sbjct: 3921 HAGRYTCSARNSA------GVAHKHVFLTVQASPVVKPLPSVVRAVAE-EEVLLPCEASG 3973
Query: 281 -QSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLE 339
+ W G + Q+ + I H D G Y C N A +
Sbjct: 3974 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHA-SPEDAGNYLCIAKNSAGSAMGKTRL 4032
Query: 340 LTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKP--------------GAEY 385
+ QV E+ +ST E S L C A P GAE
Sbjct: 4033 VV------QVPPVIENGLPDLSTTEG---SHAFLPCKARGSPEPNITWDKDGQPVSGAEG 4083
Query: 386 RWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSL 443
++T++ S +L+++ L + G Y CTA N++ G AR L +V P ++L
Sbjct: 4084 KFTIQPSG------ELLVKNLEGQDAGTYTCTAENAV-GRARRRVHLTILVLPVFTTL 4134
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 87.4 bits (215), Expect = 3e-17
Identities = 97/358 (27%), Positives = 138/358 (38%), Gaps = 48/358 (13%)
Query: 98 TIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSD------- 150
TI W + V R+Q+ +G++L I Q DSG Y C A + D
Sbjct: 1388 TIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQV 1447
Query: 151 -PIFLDVKYGPDPVEIKLESGVASGEVVE---VMEGSSMTFLAETKSHPPCAYTWFLLDS 206
P+F V EI A G V E ++E + +T + PP TW+ D
Sbjct: 1448 PPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQ 1507
Query: 207 ILS--------HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQV 258
LS R I V E+ G Y C SN L +L LT P +
Sbjct: 1508 PLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGE----DWLHYELL-VLTPPVI 1562
Query: 259 VPSSLNLVE----NARS-VDLTCQTVNQSV-NVQWFLSGQPLLPSEHLQLSADNRTLIIH 312
+ + LVE NA S V L C + V + W +G P PS LQ+ D + L +
Sbjct: 1563 LGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVS 1622
Query: 313 GLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT 372
+ D Y C N +A S T+ +V + A + + A LNSS++
Sbjct: 1623 TAEVADAASYMCVAEN---QAGSAEKLFTL-----RVQVPPRIAGLDLEQVTAILNSSVS 1674
Query: 373 LQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALT---------WEHDGIYNCTASNS 421
L C + P E W + S LGE++ + T G+Y C A N+
Sbjct: 1675 LPCDVHAHPNPEVTW-YKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNA 1731
Score = 84.0 bits (206), Expect = 4e-16
Identities = 91/363 (25%), Positives = 139/363 (38%), Gaps = 36/363 (9%)
Query: 98 TIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF-LDV 156
TI W+ N L R+Q+ +DG++L + + D+ +Y C A + S ++ +F L V
Sbjct: 1594 TISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGS--AEKLFTLRV 1651
Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILS------- 209
+ P + LE V + SS++ + +HP TW+ LS
Sbjct: 1652 QVPPRIAGLDLEQ-------VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFL 1704
Query: 210 -HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268
T T + G+Y C N+A L L V V P LV
Sbjct: 1705 LPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRV 1764
Query: 269 ARSVDLTCQT-VNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVW 327
L+C+T V W+ GQPL+ ++ Q + L I Q +D G Y+C+V
Sbjct: 1765 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVS 1824
Query: 328 NWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW 387
N A LT+ P + E+ S++ S L L C P W
Sbjct: 1825 NVAGEA-VRTFTLTVQVPPTFENPKTETVSQV-------AGSPLVLTCDVSGVPAPTVTW 1876
Query: 388 TLE----HSTGEH----LGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQ 439
+ S+ H G +L + L G Y C A N+ AR V+ +V P+
Sbjct: 1877 LKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENT-QAEARKDFVVAVLVAPR 1935
Query: 440 SSS 442
S
Sbjct: 1936 IRS 1938
Score = 74.3 bits (181), Expect = 3e-13
Identities = 87/361 (24%), Positives = 142/361 (39%), Gaps = 39/361 (10%)
Query: 99 IHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
I W V E L G +L + Q +DSG Y C A + R + ++V
Sbjct: 1102 IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRN-FSVEVLV 1160
Query: 159 GPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWF-----LLDSILSHTTR 213
P LE EV++V++G + + HP TWF L H +
Sbjct: 1161 PPSIENEDLE------EVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISP 1214
Query: 214 TFTIHAVSREH---EGLYRCLVSNSATHLSSLGTLKVRVLETL------TMPQVVPSSLN 264
+ V + + G Y C+ +N+ + L V + T+ + + V ++N
Sbjct: 1215 DGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVN 1274
Query: 265 LVENARSVDLTCQTVN-QSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYA 323
+ L C+ + S N+ W G P S ++QL L I Q+ D G Y
Sbjct: 1275 -----NPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYT 1329
Query: 324 CEVWN-WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPG 382
C V N G ++ +E+ I P + A + ++ ++NS+LTL+C + + P
Sbjct: 1330 CVVTNELGEAVKNYHVEVLI---PPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPP 1386
Query: 383 AEYRW------TLEHSTGEHLGE--QLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVK 434
RW S + LGE L I+ G Y C A+N + +VL++
Sbjct: 1387 PTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ 1446
Query: 435 V 435
V
Sbjct: 1447 V 1447
Score = 68.9 bits (167), Expect = 1e-11
Identities = 96/366 (26%), Positives = 141/366 (38%), Gaps = 46/366 (12%)
Query: 98 TIHWVS--NNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLD 155
T+ W+ N +S +Q+ G++LT+ + DSG Y C A A+ R D + L
Sbjct: 726 TLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQD-VVLQ 784
Query: 156 VKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSH--PPCAYTWFLLDSILS---- 209
V P + +L V + E V + E +SH PP +W+ L
Sbjct: 785 VHMPPSILGEELNVSVVANESVAL----------ECQSHAMPPPVLSWWKDGRPLEPRPG 834
Query: 210 -HTTRTFTIHAVSRE---HEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNL 265
H + + V R G Y C N A H L V V + + S
Sbjct: 835 VHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRE---SHTLT 891
Query: 266 VENARSVDLTCQTVNQSV-NVQWFLSGQPLLPSEHLQL---SADNRTLIIHGLQRNDTGP 321
V L+C+ + W GQP LP E L SA R L + Q G
Sbjct: 892 VREGHPTRLSCECRGVPFPKISWRKDGQP-LPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 950
Query: 322 YACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKP 381
Y CE N + S+ L+L ++ P Q+ RE ++ +S ++ + TL+C A KP
Sbjct: 951 YTCECSNVVGNS-SQDLQLEVHV-PPQIAGPREPPTQ-VSVVQ---DGVATLECNATGKP 1004
Query: 382 GAEYRWTLE-HSTGEHL-------GEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLV 433
W + G L G+ L + H G Y+C A N L G A L
Sbjct: 1005 PPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN-LAGRAERKFELS 1063
Query: 434 KVVGPQ 439
+V P+
Sbjct: 1064 VLVPPE 1069
Score = 66.6 bits (161), Expect = 6e-11
Identities = 82/318 (25%), Positives = 122/318 (38%), Gaps = 42/318 (13%)
Query: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182
L I V D G Y C A + L + + L V P+ +E G + V +E
Sbjct: 568 LQIEKVDLRDEGIYTCAATN-LAGESKREVALKVLVPPN-----IEPGPVNKAV---LEN 618
Query: 183 SSMTFLAETKSHPPCAYTWFL--------LDSILSHTTRTFTIHAVSREHEGLYRCLVSN 234
+S+T PP +WF + +S R I G YRC+ SN
Sbjct: 619 ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 678
Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQ-TVNQSVNVQWFLSGQP 293
A L+V V +T+P +P + LV V LTC T S + W G P
Sbjct: 679 VAGSTELRYGLRVNVPPRITLPPSLPGPV-LVNT--PVRLTCNATGAPSPTLMWLKDGNP 735
Query: 294 LLP--SEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHI 351
+ P + LQ+ R L + + +D+G Y+C + R + + QVH+
Sbjct: 736 VSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL--------QVHM 787
Query: 352 TRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW-----TLEHSTGEHLGEQLII--- 403
E ++ + N S+ L+C + + P W LE G HL +
Sbjct: 788 PPSILGEELN-VSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQV 846
Query: 404 -RALTWEHDGIYNCTASN 420
RA W+ G Y C A N
Sbjct: 847 DRADVWD-AGHYTCEALN 863
Score = 65.1 bits (157), Expect = 2e-10
Identities = 77/324 (23%), Positives = 115/324 (35%), Gaps = 32/324 (9%)
Query: 114 MQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVAS 173
+Q+ +DG++L I D G YQC A Q D F + P + E+G
Sbjct: 174 LQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARD--FQLRVHAPPTIWGSNETG--- 228
Query: 174 GEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTT--------RTFTIHAVSREHE 225
V VME + L E + P TWF ++L +T R +
Sbjct: 229 --EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDA 286
Query: 226 GLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVN 284
G+Y C SN+ L V V T+ P + V R V L C + S
Sbjct: 287 GVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVA-GRPVALECVARGHPSPT 345
Query: 285 VQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINY 344
+ W G P+ S +L D L + +G Y+C A S E + Y
Sbjct: 346 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCV-------ASSPAGEAVLQY 398
Query: 345 GPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHL------- 397
+ + +E + + + L L C A P +W E L
Sbjct: 399 SVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVAS 458
Query: 398 -GEQLIIRALTWEHDGIYNCTASN 420
G L I + +H G++ C A+N
Sbjct: 459 QGTTLHIDHVELDHSGLFACQATN 482
Score = 63.9 bits (154), Expect = 4e-10
Identities = 88/386 (22%), Positives = 157/386 (40%), Gaps = 38/386 (9%)
Query: 79 AIEQKDMVTFYCTTKDV---NITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGT 135
A+ + +V C + V NIT W + + ++ ++ G+ L + Q D+G
Sbjct: 231 AVMEDHLVQLLCEARGVPTPNIT--WFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGV 288
Query: 136 YQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHP 195
Y C+A +A+ LDV P +E VV+ + G + + HP
Sbjct: 289 YTCKASNAV-GAAEKATRLDVYVPPT-----IEGAGGRPYVVKAVAGRPVALECVARGHP 342
Query: 196 PCAYTWFL--LDSILSHTTRTFTIHAVSR------EHEGLYRCLVSNSATHLSSLGTLKV 247
+W L S+ +R T +V R GLY C+ S+ A +++V
Sbjct: 343 SPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEV 402
Query: 248 RVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSV-NVQWFLSGQPLLPSEHLQLSADN 306
+V L + + + +V + ++L CQ V +QW +G+P +Q+++
Sbjct: 403 QVPPQLLVAEGLGQVTTIV--GQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQG 460
Query: 307 RTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN--YGPDQVHI---TRESASEMIS 361
TL I ++ + +G +AC+ N A +E +E++++ + P + + E S
Sbjct: 461 TTLHIDHVELDHSGLFACQATNEAGTAGAE-VEVSVHGEWAPGVLEVPIGQYHWGXEHHS 519
Query: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST-GEHLG--------EQLIIRALTWEHDG 412
+ A + + A KP W S GE G L I + +G
Sbjct: 520 SFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEG 579
Query: 413 IYNCTASNSLTGLARSTSVLVKVVGP 438
IY C A+N L G ++ L +V P
Sbjct: 580 IYTCAATN-LAGESKREVALKVLVPP 604
Score = 63.5 bits (153), Expect = 5e-10
Identities = 65/238 (27%), Positives = 98/238 (41%), Gaps = 23/238 (9%)
Query: 99 IHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
I W N+ V E + G L V REDSGTY C A + + + F+ VK
Sbjct: 2878 IGWTVNDRPVT--EGVSEQDGGSTLQRAAVSREDSGTYVCWAENR-VGRTQAVSFVHVKE 2934
Query: 159 GPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWF-----LLDSILSHTTR 213
P + G A +VE + G S+ + P W L S L H +
Sbjct: 2935 AP------VLQGEAFSYLVEPV-GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ 2987
Query: 214 --TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARS 271
+ TI R+ G Y+CL N + + + VL++ + QV P + V +
Sbjct: 2988 NGSLTIRRTERDDAGRYQCLAEN---EMGVAKKVVILVLQSAPVFQVEPQDMT-VRSGDD 3043
Query: 272 VDLTCQTVNQ-SVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
V L CQ + + ++W +GQPL S L+ D +L + ++ D G Y C N
Sbjct: 3044 VALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG-SLWLENVETGDAGTYDCVAHN 3100
Score = 63.2 bits (152), Expect = 7e-10
Identities = 81/366 (22%), Positives = 144/366 (39%), Gaps = 45/366 (12%)
Query: 96 NITIH------WVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRS 149
N+T H W + + + +S DG +L +L +G Y C A +A+ +++
Sbjct: 1186 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAV-GEKT 1244
Query: 150 DPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILS 209
L V P + +S + E V V + ++ + E + P TW + D
Sbjct: 1245 KHFQLSVLLAPTILGGAEDS---ADEEVTVTVNNPISLICEALAFPSPNITW-MKDGAPF 1300
Query: 210 HTTRTFTI----HAVS-----REHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVP 260
+R + H + +E G Y C+V+N ++V + +++ +
Sbjct: 1301 EASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLA 1360
Query: 261 S-SLNLVENARSVDLTCQTVNQSV---NVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQR 316
+ V+ + LT + + +V ++W+ GQP+ PS LQ+ + R L I Q
Sbjct: 1361 EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQV 1420
Query: 317 NDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT---- 372
+D+G Y C N + + I P + SA+ I + E E +T
Sbjct: 1421 SDSGRYLCVATNVAGE-DDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYRE 1479
Query: 373 --------LQCWAESKPGAEYRWTLEH---STGEHL-----GEQLIIRALTWEHDGIYNC 416
L C + P + W E S G+ + G L I + E+ G Y+C
Sbjct: 1480 IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSC 1539
Query: 417 TASNSL 422
ASN +
Sbjct: 1540 KASNEV 1545
Score = 62.0 bits (149), Expect = 1e-09
Identities = 90/367 (24%), Positives = 129/367 (35%), Gaps = 50/367 (13%)
Query: 96 NITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEA-----RDALLSQRS- 149
N + W ++ ++ E + L L + + DSG Y CEA RD L Q S
Sbjct: 1684 NPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSV 1743
Query: 150 --DPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI 207
P F GP + V V G ET + P TW+
Sbjct: 1744 LVPPAFRQAPRGPQ-------------DAVLVRVGDKAVLSCETDALPEPTVTWYKDGQP 1790
Query: 208 LSHTTRTFTIHAVSR--------EHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVV 259
L RT + R +GLY C VSN A TL V+V T P+
Sbjct: 1791 LVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKT- 1849
Query: 260 PSSLNLVENARSVDLTCQTVN-QSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRND 318
+++ V + V LTC + V W P+ S + + L + LQ
Sbjct: 1850 -ETVSQVAGSPLV-LTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQ 1907
Query: 319 TGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAE 378
G Y C N + AR + + + P I + +E + + L C A+
Sbjct: 1908 AGTYTCVAENTQAEARKD-FVVAVLVAP---RIRSSGVAREHHVLEGQ---EVRLDCEAD 1960
Query: 379 SKPGAEYRW-----TLEHSTGEHL-----GEQLIIRALTWEHDGIYNCTASNSLTGLARS 428
+P + W L G HL G L+++ L G Y C A N AR
Sbjct: 1961 GQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARL 2020
Query: 429 TSVLVKV 435
+V V V
Sbjct: 2021 HTVNVLV 2027
Score = 61.6 bits (148), Expect = 2e-09
Identities = 90/414 (21%), Positives = 149/414 (35%), Gaps = 65/414 (15%)
Query: 62 GRSRELAKPSIAVSPG-----------TAIEQKDMVTFYCTTKDV-NITIHWVSNNLSVV 109
GR ++L + S+ V P + D C T + T+ W + +V
Sbjct: 1733 GRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLV 1792
Query: 110 FHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLES 169
+R Q + G+ L I Q D G Y C+ + + + L V+ P K E+
Sbjct: 1793 LAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSN-VAGEAVRTFTLTVQVPPTFENPKTET 1851
Query: 170 GVASGEVVEVMEGSSMTFLAETKSHPPCAYTWF---------LLDSILSHTTRTFTIHAV 220
V + GS + + P TW + ++S R + +
Sbjct: 1852 -------VSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGR-LQLSRL 1903
Query: 221 SREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSL---NLVENARSVDLTCQ 277
G Y C+ N+ K V+ L P++ S + + V + V L C+
Sbjct: 1904 QPAQAGTYTCVAENTQAEAR-----KDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCE 1958
Query: 278 TVNQSV-NVQWFLSGQPLLPS--EHLQLSADNRTLIIHGLQRNDTGPYACEVWN-WGSRA 333
Q +V W G PL HL+ D +L++ GL+ +D G Y C N G A
Sbjct: 1959 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDA 2018
Query: 334 RSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW------ 387
R T+N V T + ++ T+ + +T+ C P W
Sbjct: 2019 RLH----TVNV---LVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLP 2071
Query: 388 ------TLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
TL H + G L I + GI+ C A++ R+ ++ V+V
Sbjct: 2072 LPLSQRTLLHGS----GHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQV 2121
Score = 58.2 bits (139), Expect = 2e-08
Identities = 105/471 (22%), Positives = 167/471 (35%), Gaps = 61/471 (12%)
Query: 7 WGHHWMGILLSA--SLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRS 64
WG H L+ S ++W P + + P + D+ T + G S
Sbjct: 533 WGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGES 592
Query: 65 RE------LAKPSIAVSP-GTAIEQKDMVTFYCTTKDVNIT-IHWVSNNLSVVFHERMQL 116
+ L P+I P A+ + VT C V + W + V + +
Sbjct: 593 KREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTV 652
Query: 117 SKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYG---PDPVEIKLESGVAS 173
S DG++L I Q D+G+Y+C A + S +++YG P I L +
Sbjct: 653 SVDGRVLRIEQAQLSDAGSYRCVASNVAGS-------TELRYGLRVNVPPRITLPPSLPG 705
Query: 174 GEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHT----------TRTFTIHAVSRE 223
V+ + + P W + +S R T+ +
Sbjct: 706 ----PVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARAS 761
Query: 224 HEGLYRCLVSNSATHLSSLGTLKVRVLETLTM-PQVVPSSLNL-VENARSVDLTCQTVNQ 281
G Y C+ +S++G + V+ + M P ++ LN+ V SV L CQ+
Sbjct: 762 DSGRYSCVA------VSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAM 815
Query: 282 SVNV-QWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLEL 340
V W+ G+PL P + LSAD L + D G Y CE N +A
Sbjct: 816 PPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALN---QAGHSEKHY 872
Query: 341 TINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQ 400
+N V RES + T+ + L+ +C P +R + GE G Q
Sbjct: 873 NLNVWVAPVFPLRESHT---LTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQ 929
Query: 401 --------LIIRALTWEHDGIYNCTAS----NSLTGLARSTSVLVKVVGPQ 439
L + +G Y C S NS L V ++ GP+
Sbjct: 930 HVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPR 980
Score = 51.2 bits (121), Expect = 3e-06
Identities = 70/329 (21%), Positives = 116/329 (35%), Gaps = 41/329 (12%)
Query: 116 LSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGE 175
+S G++L + Q GTY CE + ++ S + L+V P ++
Sbjct: 931 VSAVGRLLYLGQAQLAQEGTYTCECSN-VVGNSSQDLQLEVHVPP-----QIAGPREPPT 984
Query: 176 VVEVMEGSSMTFLAETKSHPPCAYTWFL--------LDSILSHTTRTFTIHAVSREHEGL 227
V V++ T PP TW L L + ++ + H G
Sbjct: 985 QVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGR 1044
Query: 228 YRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARS-----VDLTCQTVN-Q 281
Y C+ N A L V V P + L+ + N + + L C+ +
Sbjct: 1045 YSCVAENLAGRAERKFELSVLV------PPELIGDLDPLTNITAALHSPLTLLCEAMGIP 1098
Query: 282 SVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELT 341
++WF +P+ P E L A L + Q D+G Y+C N AR +
Sbjct: 1099 PPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRN-FSVE 1157
Query: 342 INYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW-----TLEHSTGEH 396
+ P I E E+I ++ + + L C P + W L H
Sbjct: 1158 VLVPPS---IENEDLEEVIKVLDGQ---TAHLMCNVTGHPQPKLTWFKDGRPLARGDAHH 1211
Query: 397 L---GEQLIIRALTWEHDGIYNCTASNSL 422
+ G L + G Y+C A+N++
Sbjct: 1212 ISPDGVLLQVLQANLSSAGHYSCIAANAV 1240
Score = 50.1 bits (118), Expect = 6e-06
Identities = 75/323 (23%), Positives = 116/323 (35%), Gaps = 40/323 (12%)
Query: 115 QLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASG 174
Q + G L + V DSGTY C A R F P +E SG
Sbjct: 2168 QSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH--FQLTVMEPPHIE-------DSG 2218
Query: 175 EVVEVM--EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHE-GLYRCL 231
+ E+ G+ M L + + P TW L+ V R + GLY CL
Sbjct: 2219 QPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCL 2278
Query: 232 VSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSG 291
+ A + ++V+ + P+ + L ++ + + + + W G
Sbjct: 2279 AESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEA-EPAPKITWHRDG 2337
Query: 292 QPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN-WGSRARSEPLEL----TINYGP 346
L H Q R L + L D+G Y+C N GS + + +E+ TI GP
Sbjct: 2338 IVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGP 2397
Query: 347 DQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEH-------STGEHLGE 399
V+++ +N + L C A+ P W + E L E
Sbjct: 2398 PAVNVS--------------VNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPE 2443
Query: 400 -QLIIRALTWEHDGIYNCTASNS 421
L I+ + + G Y C ASNS
Sbjct: 2444 GSLRIQPVLAQDAGHYLCLASNS 2466
Score = 48.9 bits (115), Expect = 1e-05
Identities = 75/302 (24%), Positives = 113/302 (37%), Gaps = 36/302 (11%)
Query: 133 SGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETK 192
+G Y C AR++ +FL V+ PV L S VV + + E
Sbjct: 2640 AGRYTCSARNSA-GVAHKHVFLTVQ--ASPVVKPLPS------VVRAVAEEEVLLPCEAS 2690
Query: 193 SHPPCAYTWFL--LDSILSHTTRTFT-----IHAVSREHEGLYRCLVSNSATHLSSLGTL 245
P TW L+ +T+ I S E G Y C+ NSA S++G
Sbjct: 2691 GIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG--SAMGKT 2748
Query: 246 KVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQ-SVNVQWFLSGQPLLPSEHLQLSA 304
++ V + +P L+ E + + L C+ N+ W GQP+ +E
Sbjct: 2749 RLVVQVPPVIENGLPD-LSTTEGSHAF-LPCKARGSPEPNITWDKDGQPVSGAEGKFTIQ 2806
Query: 305 DNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIE 364
+ L++ L+ D G Y C N RAR + LTI P + + +
Sbjct: 2807 PSGELLVKNLEGQDAGTYTCTAENAVGRARRR-VHLTILVLPVFTTLPGDRS-------- 2857
Query: 365 AELNSSLTLQCWAESKPGAEYRWTL------EHSTGEHLGEQLIIRALTWEHDGIYNCTA 418
L L L+C A P WT+ E + + G L A++ E G Y C A
Sbjct: 2858 LRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWA 2917
Query: 419 SN 420
N
Sbjct: 2918 EN 2919
Score = 48.1 bits (113), Expect = 2e-05
Identities = 61/225 (27%), Positives = 89/225 (39%), Gaps = 29/225 (12%)
Query: 226 GLYRCLVSNSATHLSSLGTLKVRV-LETLTMPQVVPSSLN---LVENARSVDLTCQTVN- 280
GLY C N A GT + L LT P V+ + L V+L C T
Sbjct: 100 GLYSCRAENQA------GTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGV 153
Query: 281 QSVNVQWFLSGQPLLPS-EHLQLSADNRTLIIHGLQRNDTGPYACEVWN-WGSRARSEPL 338
+ V+W QP+LP HLQ+ D + L I G D G Y C ++ G +AR L
Sbjct: 154 PTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQL 213
Query: 339 ELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRW--------TLE 390
+ + P + + E+ ++ +E L + L C A P W T
Sbjct: 214 RV---HAPPTIWGSNETGE--VAVMEDHL---VQLLCEARGVPTPNITWFKDGALLPTST 265
Query: 391 HSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435
G QL + G+Y C ASN++ ++T + V V
Sbjct: 266 KVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV 310
Score = 42.0 bits (97), Expect = 0.002
Identities = 90/371 (24%), Positives = 132/371 (35%), Gaps = 52/371 (14%)
Query: 99 IHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
I W + + + Q + G+ L + + DSG Y C AR+A S V +
Sbjct: 2331 ITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGST-------SVAF 2383
Query: 159 GPDPVEIKLESGVASGE-VVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTI 217
VEI + SG V V + + P +W L + F I
Sbjct: 2384 R---VEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEI 2440
Query: 218 --------HAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENA 269
V + G Y CL SNSA + R L L P + PS NL A
Sbjct: 2441 LPEGSLRIQPVLAQDAGHYLCLASNSAG-----SDRQGRDLRVLEPPAIAPSPSNLTLTA 2495
Query: 270 RSVDLTCQTVNQSVN--VQWFLSGQPLLPSEHLQLSA----DNRTLIIHGLQRNDTGPYA 323
+ L + S V W+ GQ L LQ A + L++ D+ +
Sbjct: 2496 HTPALLPCEASGSPKPLVVWWKDGQKL--DFRLQQGAYRLLPSNALLLTAPGPQDSAQFE 2553
Query: 324 CEVWNWGSRARSEPLELTINYGP----DQVHITRESASEMISTIEAELNSSLTLQCWAES 379
C V N A ++T++ P DQ T + ++ T + + T+ W S
Sbjct: 2554 CVVSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS-W--S 2609
Query: 380 KPGAEY-----RWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVK 434
K GA+ + + S +G+ L I H G Y C+A NS G+A L
Sbjct: 2610 KAGAQLGARGSGYRVSPSGALEIGQALPI------HAGRYTCSARNS-AGVAHKHVFLTV 2662
Query: 435 VVGPQSSSLSS 445
P L S
Sbjct: 2663 QASPVVKPLPS 2673
Score = 36.2 bits (82), Expect = 0.088
Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 16/158 (10%)
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMI 360
+L + ++L +Q D+G Y+C N A+ + L + P V + +A E++
Sbjct: 81 RLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLT--PPSV-LGAGAAQEVL 137
Query: 361 STIEAELNSSLTLQCWAESKPGAEYRWTLEHST----GEHL-----GEQLIIRALTWEHD 411
A++ LQCW P + WT + G HL G+ L I +
Sbjct: 138 GLAGADVE----LQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDE 193
Query: 412 GIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIA 449
G Y C A + AR + V S +G +A
Sbjct: 194 GRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVA 231
Score = 34.7 bits (78), Expect = 0.26
Identities = 60/238 (25%), Positives = 85/238 (35%), Gaps = 42/238 (17%)
Query: 224 HEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVV---PSSLNLVENARSVDLTCQTVN 280
H G Y C NSA G V T+ VV PS + V V L C+
Sbjct: 2639 HAGRYTCSARNSA------GVAHKHVFLTVQASPVVKPLPSVVRAVAE-EEVLLPCEASG 2691
Query: 281 -QSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLE 339
+ W G + Q+ + I H D G Y C N A +
Sbjct: 2692 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHA-SPEDAGNYLCIAKNSAGSAMGKTRL 2750
Query: 340 LTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKP--------------GAEY 385
+ QV E+ +ST E S L C A P GAE
Sbjct: 2751 VV------QVPPVIENGLPDLSTTEG---SHAFLPCKARGSPEPNITWDKDGQPVSGAEG 2801
Query: 386 RWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSL 443
++T++ S +L+++ L + G Y CTA N++ G AR L +V P ++L
Sbjct: 2802 KFTIQPSG------ELLVKNLEGQDAGTYTCTAENAV-GRARRRVHLTILVLPVFTTL 2852
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,697,824
Number of Sequences: 37866
Number of extensions: 1191634
Number of successful extensions: 6864
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 292
Number of HSP's that attempted gapping in prelim test: 4428
Number of HSP's gapped (non-prelim): 1744
length of query: 596
length of database: 18,247,518
effective HSP length: 108
effective length of query: 488
effective length of database: 14,157,990
effective search space: 6909099120
effective search space used: 6909099120
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.