BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|154355000 KH-type splicing regulatory protein [Homo sapiens] (711 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 1515 0.0 gi|17402900 far upstream element-binding protein [Homo sapiens] 798 0.0 gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 535 e-152 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 86 2e-16 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 85 2e-16 gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 85 2e-16 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 84 3e-16 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 84 3e-16 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 84 3e-16 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 84 3e-16 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 84 3e-16 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 84 3e-16 gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 82 2e-15 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 80 5e-15 gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 80 5e-15 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 80 5e-15 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 80 7e-15 gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 80 9e-15 gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 77 7e-14 gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 77 7e-14 gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 76 1e-13 gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 75 2e-13 gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 75 2e-13 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 75 2e-13 gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 75 3e-13 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 73 8e-13 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 73 8e-13 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 73 8e-13 gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 73 1e-12 gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 73 1e-12 >gi|154355000 KH-type splicing regulatory protein [Homo sapiens] Length = 711 Score = 1515 bits (3923), Expect = 0.0 Identities = 711/711 (100%), Positives = 711/711 (100%) Query: 1 MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60 MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ Sbjct: 1 MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60 Query: 61 PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120 PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES Sbjct: 61 PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120 Query: 121 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI 180 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI Sbjct: 121 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI 180 Query: 181 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI 240 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI Sbjct: 181 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI 240 Query: 241 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM 300 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM Sbjct: 241 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM 300 Query: 301 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ Sbjct: 301 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360 Query: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW Sbjct: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420 Query: 421 GPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS 480 GPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS Sbjct: 421 GPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS 480 Query: 481 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH 540 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH Sbjct: 481 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH 540 Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA 600 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA Sbjct: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA 600 Query: 601 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT 660 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT Sbjct: 601 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT 660 Query: 661 GGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ 711 GGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ Sbjct: 661 GGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ 711 >gi|17402900 far upstream element-binding protein [Homo sapiens] Length = 644 Score = 798 bits (2060), Expect = 0.0 Identities = 426/703 (60%), Positives = 487/703 (69%), Gaps = 96/703 (13%) Query: 34 PPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAA 93 PP +G GGGG GGGG G DAF DA+QRARQIAAKIGGDA Sbjct: 9 PPSSGSAGGGGGGGGGGG------------------VNDAFKDALQRARQIAAKIGGDAG 50 Query: 94 TTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIH-PPPRTSMTEEYRVP 152 T++N++ D+G+GGQKR LEDGDQP++KK+A Q DS +QL P+H R+ MTEEY+VP Sbjct: 51 TSLNSN--DYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVP 108 Query: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIV 212 DGMVG IIGRGGEQI++IQQ+SGCK+QI+PDSGGLPERS LTG PESVQ AK +LD IV Sbjct: 109 DGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIV 168 Query: 213 SRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQD 272 +GR P FH G VQEIMIPA KAGLVIGKGGETIKQLQERAGVKM++IQD Sbjct: 169 EKGRPAP--GFHH--GDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQD 224 Query: 273 GSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGD-RNEYGSRIGG--GIDVPV 329 G QNT DKPLRI GDPYKVQQA EMV++++ RDQGGF + RNEYGSRIGG GIDVP+ Sbjct: 225 GPQNTGADKPLRITGDPYKVQQAKEMVLELI--RDQGGFREVRNEYGSRIGGNEGIDVPI 282 Query: 330 PRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDL 389 PR +VG+VIGR+GEMIKKIQNDAGVRIQFK DDGT PE+IA I GPPDRC+HAA II DL Sbjct: 283 PRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDL 342 Query: 390 LQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW--GPPGG--EMTFSIPTHKCGLVIGRGGE 445 L+S+++G PG PG PGGRGRGRGQGNW GPPGG E F +PT K GL+IG+GGE Sbjct: 343 LRSVQAGNPGGPG-----PGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGE 397 Query: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP- 504 +K+I+QQ+GA +E+ R PPN DPN KLF IRG+PQQID+A+QLIEEKI GP+ P+GP Sbjct: 398 TIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPP 457 Query: 505 -------------GPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTY 551 PG PGP PMGP+NP P+N GPPG PH PP Y PQGWGN Y Sbjct: 458 VPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHG---PPAPYAPQGWGNAY 514 Query: 552 PQWQPPAPHDPSKAAAAAADPN-AAWAAYYSHYYQ---QPPGPVPGPAPAPAAPPAQGEP 607 P WQ AP DP+K A DPN AAWAAYY+HYYQ QPP P AP QG+ Sbjct: 515 PHWQQQAPPDPAK---AGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQ 571 Query: 608 PQPPPTGQSDYTKAWEEYYKKIGQQ-PQQPGAPP--QQDYTKAWEEYYKKQAQVATGGGP 664 P P GQ DYTKAWEEYYKK+GQ P GAPP Q DY+ AW EYY+ Sbjct: 572 QNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYR----------- 620 Query: 665 GAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQ 707 QQAAYY QT G PQ PP QGQ Sbjct: 621 -------------------QQAAYYAQTSPQGMPQHPPAPQGQ 644 Score = 643 bits (1658), Expect = 0.0 Identities = 379/675 (56%), Positives = 436/675 (64%), Gaps = 127/675 (18%) Query: 50 PGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQK 109 P GSAGG GGGG G DAF DA+QRARQIAAKIGGDA T++N++ D+G+GGQK Sbjct: 10 PSSGSAGGGG---GGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSN--DYGYGGQK 64 Query: 110 RQLEDGDQPESKKLASQGDSISSQLGPIHPPP-RTSMTEEYRVPDGMVGLIIGRGGEQIN 168 R LEDGDQP++KK+A Q DS +QL P+H R+ MTEEY+VPDGMVG IIGRGGEQI+ Sbjct: 65 RPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQIS 124 Query: 169 KIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNAN 228 +IQQ+SGCK+QI+PDSGGLPERS LTG PESVQ AK +LD IV +GR P FH Sbjct: 125 RIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPG--FHHG-- 180 Query: 229 GGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGD 288 G VQEIMIPA KAGLVIGKGGETIKQLQERAGVKM++IQDG QNT DKPLRI GD Sbjct: 181 DGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGD 240 Query: 289 PYKVQQACEMVMDILRERDQGGFGD-RNEYGSRIGG--GIDVPVPRHSVGVVIGRSGEMI 345 PYKVQQA EMV++++R DQGGF + RNEYGSRIGG GIDVP+PR +VG+VIGR+GEMI Sbjct: 241 PYKVQQAKEMVLELIR--DQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMI 298 Query: 346 KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPG 405 KKIQNDAGVRIQFK DDGT PE+IA I GPPDRC+HAA II DLL+S+++G PG PG Sbjct: 299 KKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPG--- 355 Query: 406 MPPGGRGRGRGQGNW--GPPGG--EMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEIS 461 PGGRGRGRGQGNW GPPGG E F +PT K GL+IG+GGE +K+I+QQ+GA +E+ Sbjct: 356 --PGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQ 413 Query: 462 RQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPG 521 R PPN DPN KLF IRG+PQQID+A+QLIEEKI GP+ P+GP P P GP G PG Sbjct: 414 RNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGP----PVPHGPHGV--PG 467 Query: 522 PFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYS 581 P GPPG PP P G N PAP++P Sbjct: 468 P--HGPPG--------PPGPGTPMGPYN-------PAPYNPG------------------ 492 Query: 582 HYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQ 641 PPGP P PAP AP + W Y QQ APP Sbjct: 493 -----PPGPAPHGPPAPYAP------------------QGWGNAYPHWQQQ-----APPD 524 Query: 642 QDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQ 699 A G+ P+ SAAWA YY A YY Q P P P Sbjct: 525 P-----------------------AKAGTDPN-SAAWAAYY---AHYYQQQAQPPPAAPA 557 Query: 700 PPPTQ-----QGQQQ 709 PT QG QQ Sbjct: 558 GAPTTTQTNGQGDQQ 572 Score = 37.4 bits (85), Expect = 0.049 Identities = 34/93 (36%), Positives = 38/93 (40%), Gaps = 17/93 (18%) Query: 7 GGP-----PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG---GGPGGGGPGGGSAGGP 58 GGP PP P P G G G PPGPPG G G P GP G + GP Sbjct: 448 GGPVNPLGPPVPHGPHGVPGPHG------PPGPPGPGTPMGPYNPAPYNPGPPGPAPHGP 501 Query: 59 SQPPGGGGPGIRKDAFADAVQRARQIAAKIGGD 91 P G G +A+ Q+A AK G D Sbjct: 502 PAPYAPQGWG---NAYPHWQQQAPPDPAKAGTD 531 >gi|100816392 far upstream element (FUSE) binding protein 3 [Homo sapiens] Length = 572 Score = 535 bits (1378), Expect = e-152 Identities = 310/638 (48%), Positives = 403/638 (63%), Gaps = 98/638 (15%) Query: 68 GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTP-----DFGFGGQKRQLEDGDQPESKK 122 G++ + F DA+ R RQIAAKI D+ +NNSTP +G+G QKR L+DG Sbjct: 13 GMKAEGFVDALHRVRQIAAKI--DSIPHLNNSTPLVDPSVYGYGVQKRPLDDG------- 63 Query: 123 LASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISP 182 + +QLG + RT +TEE++VPD MVG IIGRGGEQI++IQ +SGCK+QI+ Sbjct: 64 -------VGNQLGAL-VHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIAS 115 Query: 183 DSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPA 242 +S G+PER LTG PES+++AK +L IV R R GP FH++ + N T+QEI+IPA Sbjct: 116 ESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPG--FHNDIDS--NSTIQEILIPA 171 Query: 243 GKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDI 302 K GLVIG+GGETIKQLQER GVKM++IQDG T DKPLRI GD +KVQQA EMV++I Sbjct: 172 SKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEI 231 Query: 303 LRERDQGGF-GDRNEYGSRIGGG-IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360 +RE+DQ F G R ++ SR+GGG I+V VPR +VG+VIGR+GEMIKKIQNDAGVRIQFK Sbjct: 232 IREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKP 291 Query: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420 DDG PE+ A +MGPPDRC+HAA II++L+ + + G G RGRGRG+G+W Sbjct: 292 DDGISPERAAQVMGPPDRCQHAAHIISELILTAQERD-----GFGGLAAARGRGRGRGDW 346 Query: 421 --GPPGG--EMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFI 476 G PGG E+T+++P KCGLVIG+GGEN+K+INQQ+GA VE+ R PPN DPN + F Sbjct: 347 SVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFT 406 Query: 477 IRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGG 536 IRG PQQI+ A+QLI+EK+ GG P G F PF+Q P APPH Sbjct: 407 IRGVPQQIEVARQLIDEKV-----------GGTNLGAP-GAFGQSPFSQPP--APPHQ-- 450 Query: 537 PPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAP 596 + +PP+ G P+ AA +P++ PV GP Sbjct: 451 ---NTFPPRSSGCF-----------PNMAAKVNGNPHST--------------PVSGP-- 480 Query: 597 APAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQA 656 P G +AW++ +++ Q QP + Q +Y+KAWE+YYKKQ+ Sbjct: 481 -----------PAFLTQGWGSTYQAWQQPTQQVPSQQSQPQSS-QPNYSKAWEDYYKKQS 528 Query: 657 QVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPG 694 A+ + P PDY+ AWAEYYRQQ A+YGQT G Sbjct: 529 HAASAAPQASSP---PDYTMAWAEYYRQQVAFYGQTLG 563 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 85.5 bits (210), Expect = 2e-16 Identities = 193/763 (25%), Positives = 245/763 (32%), Gaps = 159/763 (20%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGPP------PGPPG--AGDRGGGGPGGGGPGG--GSAG 56 G PG P P G G G G P PGP G GD G PG GP G G G Sbjct: 899 GRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTG 958 Query: 57 --GPSQPPG-------GGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGG 107 GP PPG G PG R + +G T + G G Sbjct: 959 FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG 1018 Query: 108 QKRQL-EDGDQPESKKLASQGDSISSQL-GPIHPPPRTSMTEEYRVPDGMVGLIIGRGGE 165 E G + K ++GD + L G PP + +P G VG + +G E Sbjct: 1019 PPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLP-GPVGALGLKGNE 1077 Query: 166 QINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHD 225 +G + P P + + G P G GPPG + Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGP---IGIPGRP----------------GPQGPPGPAGE 1118 Query: 226 NANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285 G+ G PAG+ GL G L AG +DG + Sbjct: 1119 KGAPGEKGP----QGPAGRDGLQGPVG------LPGPAGPVGPPGEDGDKGE-------- 1160 Query: 286 IGDPYKVQQACEMVMDILRERDQGGFGDRNEYG----SRIGGGIDVPVPRHSVGVVIGRS 341 IG+P +G GD+ E G + G I P P + G R Sbjct: 1161 IGEP----------------GQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG 1204 Query: 342 GEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPP 401 + + + D G R GP + + GPP + + GPPGPP Sbjct: 1205 QQGLFGQKGDEGPR---GFPGPPGPVGLQGLPGPPGEKGETGDV-------GQMGPPGPP 1254 Query: 402 G-----------GPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAI 450 G GP PPGG G G G PG +P + G +G K Sbjct: 1255 GPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLP-GEGGPPGPKGERGEKGE 1313 Query: 451 NQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPL-CPVGPG-PGG 508 + +GA + PP D +GSP GP+ P PG PG Sbjct: 1314 SGPSGAAGPPGPKGPPGDDGP------KGSP---------------GPVGFPGDPGPPGE 1352 Query: 509 PGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDP------ 562 PGPAG GP P ++G G P G P P P G + PP P P Sbjct: 1353 PGPAGQDGP----PGDKGDDGEPGQTGSPGPTGEP--GPSGPPGKRGPPGPAGPEGRQGE 1406 Query: 563 --SKAAAAAADPNAAWAAYYSHYYQQPPGP-----VPGP--------APAPAAPPAQGEP 607 +K A P PGP +PGP +P P PP P Sbjct: 1407 KGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGP 1466 Query: 608 PQPPPTGQSDYTKAWEEYYKKIG--QQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG--- 662 P P K + + IG P + G + K Q TG Sbjct: 1467 PGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGP 1526 Query: 663 -GPGAPPGSQPDYSAAWAEYYRQQAAYYGQT--PGPGGPQPPP 702 GP PPG A+ G+ PGP GP PP Sbjct: 1527 IGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPP 1569 Score = 80.5 bits (197), Expect = 5e-15 Identities = 202/772 (26%), Positives = 247/772 (31%), Gaps = 163/772 (21%) Query: 8 GPPPGPPPPA-GGGGGAGGAGG-----GPP-----------PGPPGAGDRGGGGPGGGGP 50 GP P PP G GA G G GPP PG PGA D G PG GP Sbjct: 712 GPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGA-DGPPGHPGKEGP 770 Query: 51 GGGSAG-GPSQPPGG-GGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQ 108 G G GP P G G PG R AD ++ + + G D D G G Sbjct: 771 PGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKG---DMGIKGD 827 Query: 109 KRQL-------EDGDQPESKKLASQGDSISSQLGPIHPP--------PRTSMTEEYRVPD 153 + ++ EDG + + GD GP+ PP P + P Sbjct: 828 RGEIGPPGPRGEDGPEGPKGRGGPNGDP-----GPLGPPGEKGKLGVPGLPGYPGRQGPK 882 Query: 154 GMVGL--IIGRGGEQINK-IQQDSGCKVQISPDSGGLPERSV-SLTGAPESVQKAKMMLD 209 G +G G GE+ + G + Q P +G ER +TG P + Sbjct: 883 GSIGFPGFPGANGEKGGRGTPGKPGPRGQRGP-TGPRGERGPRGITGKPGPKGNSG---- 937 Query: 210 DIVSRGRGGPPGQFHDNANGGQNG--TVQEIMIPAGKAGLV--IGKGGETIKQLQERAGV 265 G GPPG+ N G G + P GK GL G+ GET Q Sbjct: 938 ---GDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ------- 987 Query: 266 KMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGI 325 T P ++G QG G+ G R G Sbjct: 988 ---------GKTGPPGPPGVVG-------------------PQGPTGETGPMGERGHPGP 1019 Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385 P + + G+ G + D G +D G G P Sbjct: 1020 PGPPGEQGLPGLAGKEG-----TKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP------- 1067 Query: 386 INDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRG 443 + L GPPGPP GP PG RG G G PG G P + G +G Sbjct: 1068 VGALGLKGNEGPPGPP-GPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKG 1126 Query: 444 GENVKAINQQTG--AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCP 501 + + G + + P G+ K I G P Q E+ GP P Sbjct: 1127 PQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEI--GEPGQKGSKGDKGEQGPPGPTGP 1184 Query: 502 VG----PGPGG----PGPAGPMGPF----NPGPFNQGPPGAPPHAG-----GPPPHQYPP 544 G PGP G PGP G G F + GP +G PG P G GPP + Sbjct: 1185 QGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP--RGFPGPPGPVGLQGLPGPPGEKGET 1242 Query: 545 QGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV--PGPAPAPAAPP 602 G P PP P PS A A Q PPG + PG P Sbjct: 1243 GDVGQMGPP-GPPGPRGPSGAPGADGP-------------QGPPGGIGNPGAVGEKGEPG 1288 Query: 603 AQGEPPQP---PPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVA 659 GEP P P G E P P PP D K V Sbjct: 1289 EAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG------SPGPVG 1342 Query: 660 TGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPG-----GPQPPPTQQG 706 G PG PPG + GQT PG GP PP ++G Sbjct: 1343 FPGDPG-PPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRG 1393 Score = 80.1 bits (196), Expect = 7e-15 Identities = 197/747 (26%), Positives = 253/747 (33%), Gaps = 133/747 (17%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGG-GPGG--GSAGGPSQPPGGG 65 P GPP P G G G G P G PG G RG GP G GP G G G QP G Sbjct: 650 PSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKG 709 Query: 66 GPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLAS 125 G + + Q G A + G G+K L P Sbjct: 710 NVGPQGEPGPPGQQ---------GNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMP---- 756 Query: 126 QGDSISSQLGPIHP----PPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQIS 181 + P HP PP + P G +G RG + + I+ G K + Sbjct: 757 -----GADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKG 811 Query: 182 PDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIP 241 D G P + ++ + + RG GP G GG NG + P Sbjct: 812 ED--GFPGFKGDM-----GIKGDRGEIGPPGPRGEDGPEGP---KGRGGPNGDPGPLGPP 861 Query: 242 AGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMD 301 K L G + R G K + G N +K R G P K + Sbjct: 862 GEKGKL----GVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGR--GTPGKPGPRGQ---- 911 Query: 302 ILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQD 361 +G G R E G R G P P+ + G G +G ++ N Sbjct: 912 ------RGPTGPRGERGPR--GITGKPGPKGNSGGD-GPAGPPGERGPN----------- 951 Query: 362 DGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--PGGRGRGRGQGN 419 GP+ GP GPPGPPG G+P PG RG QG Sbjct: 952 ---GPQGPTGFPGP-------------------KGPPGPPGKDGLPGHPGQRGETGFQGK 989 Query: 420 WGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQTG----AFVEISRQLP-------P 466 GPPG G + PT + G + RG + G A E ++ P Sbjct: 990 TGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGK 1049 Query: 467 NGDPNFKLFI-IRGSPQQIDHAKQLIEEKIEGPLCPVG-PGPGGP-GPAGPMG-PFNPGP 522 +G P + F RG P + E GP P G PG GP G AGP+G P PGP Sbjct: 1050 DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGP 1109 Query: 523 FNQGPPGAPPHAGGPPPHQYP--PQGWGNTYPQWQPPAPHDPSKAAAAAADPN-----AA 575 QGPPG P G P + P P G P P P D Sbjct: 1110 --QGPPG-PAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQ 1166 Query: 576 WAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSD-YTKAWEEYYKKIGQQPQ 634 + Q PPGP GP P G +P P GQ + + +E + P Sbjct: 1167 KGSKGDKGEQGPPGPT-GPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225 Query: 635 Q------PGAPPQQDYTKAWEEYYKKQAQVATG--GGPGA-----PPGSQPDYSAAWAEY 681 PG P ++ T + G G PGA PPG + A + Sbjct: 1226 PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKG 1285 Query: 682 YRQQAAYYGQTPGPGGPQPPPTQQGQQ 708 +A G PG GGP P ++G++ Sbjct: 1286 EPGEAGEPG-LPGEGGPPGPKGERGEK 1311 Score = 77.8 bits (190), Expect = 3e-14 Identities = 195/762 (25%), Positives = 243/762 (31%), Gaps = 144/762 (18%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAG-GPSQPPGG-GGPG 68 PGP G G G G PG PGA D G PG GP G G GP P G G PG Sbjct: 732 PGPQGAIGPPGEKGPLGKPGLPGMPGA-DGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPG 790 Query: 69 IRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQL-------EDGDQPESK 121 R AD ++ + + G D D G G + ++ EDG + Sbjct: 791 PRGVKGADGIRGLKGTKGEKGEDGFPGFKG---DMGIKGDRGEIGPPGPRGEDGPEGPKG 847 Query: 122 KLASQGDSISSQLGPIHPP--------PRTSMTEEYRVPDGMVGL--IIGRGGEQINK-I 170 + GD GP+ PP P + P G +G G GE+ + Sbjct: 848 RGGPNGDP-----GPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGT 902 Query: 171 QQDSGCKVQISPDSGGLPERSV-SLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANG 229 G + Q P +G ER +TG P + G GPPG+ N Sbjct: 903 PGKPGPRGQRGP-TGPRGERGPRGITGKPGPKGNSG-------GDGPAGPPGERGPNGPQ 954 Query: 230 GQNGTV--QEIMIPAGKAGLV--IGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285 G G + P GK GL G+ GET Q T P + Sbjct: 955 GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ----------------GKTGPPGPPGV 998 Query: 286 IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMI 345 +G QG G+ G R G P + + G+ G Sbjct: 999 VGP-------------------QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGT-- 1037 Query: 346 KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPG 405 + D G +D G G P + L GPPGPPG P Sbjct: 1038 ---KGDPGPAGLPGKDGPPGLRGFPGDRGLPGP-------VGALGLKGNEGPPGPPG-PA 1086 Query: 406 MPPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQTG--AFVEIS 461 PG RG G G PG G P + G +G + + G + Sbjct: 1087 GSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPA 1146 Query: 462 RQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP----GPGG----PGPAG 513 + P G+ K I G P Q E+ GP P GP GP G PGP G Sbjct: 1147 GPVGPPGEDGDKGEI--GEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG 1204 Query: 514 PMGPF----NPGPFNQGPPGAPPHAG-----GPPPHQYPPQGWGNTYPQWQPPAPHDPSK 564 G F + GP +G PG P G GPP + G P PP P PS Sbjct: 1205 QQGLFGQKGDEGP--RGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPG-PPGPRGPSG 1261 Query: 565 AAAAAADPNAAWAAYYSHYYQQPPGPV--PGPAPAPAAPPAQGEPPQPP---PTGQSDYT 619 A A Q PPG + PG P GEP P P G Sbjct: 1262 APGADGP-------------QGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGER 1308 Query: 620 KAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPG-----APPGSQPDY 674 E P P PP D K G PG PPG + D Sbjct: 1309 GEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDD 1368 Query: 675 SAAWAEYYRQQAAYYGQTPGPG-----GPQPPPTQQGQQQAQ 711 G + PG GP P +QG++ A+ Sbjct: 1369 GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAK 1410 Score = 65.5 bits (158), Expect = 2e-10 Identities = 191/773 (24%), Positives = 250/773 (32%), Gaps = 155/773 (20%) Query: 8 GPP--------PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPS 59 GPP PGPP G G G G PPG PG G G GP G P Sbjct: 469 GPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLP----GADGLPGPPGTMLMLPF 524 Query: 60 QPPGGGGPGIR------KDAFADAVQRARQIAAK--IGGDAATTVNNSTPDFGFGGQKRQ 111 + GGG G + +++ A A+ + ++A + G T G GG K Sbjct: 525 RFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKG- 583 Query: 112 LEDGDQPESKKLASQGDSISSQLGPIHPPPRTSM--TEEYRVPDGMVGLIIGRGGEQINK 169 E GD QG GP P R ++ R G G RG + + Sbjct: 584 -EPGDVGPQGPRGVQGPP-----GPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAG 637 Query: 170 IQQDSGCKVQISPDS-----GGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFH 224 + + G + P G ER P + + +G GPPG Sbjct: 638 LPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPG 697 Query: 225 DNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLR 284 GQ G P G +G GE Q+ G+Q + P Sbjct: 698 VTGMDGQPG-------PKGN----VGPQGEPGPPGQQG--------NPGAQ--GLPGPQG 736 Query: 285 IIGDPYKVQQACEMVMDILRERD--QGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSG 342 IG P + + + + D G G G + GG P P+ +G R Sbjct: 737 AIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEK--GGQGPPGPQGPIGYPGPRGV 794 Query: 343 EMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPG 402 + I+ G + + +D G + I G DR E GPPGP G Sbjct: 795 KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKG--DRGE--------------IGPPGPRG 838 Query: 403 GPGMPPGGRGRGRGQGN---WGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVE 459 G P G +GRG G+ GPPG + +P GL G + K G F Sbjct: 839 EDG-PEGPKGRGGPNGDPGPLGPPGEKGKLGVP----GLPGYPGRQGPKGSIGFPG-FPG 892 Query: 460 ISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG-PGP----GGPGPAGP 514 + + G P G P GP G PGP GG GPAGP Sbjct: 893 ANGEKGGRGTP--------GKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGP 944 Query: 515 MGPFNPG--------PFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAA 566 G P P +GPPG PP G P H P G T Q + P P Sbjct: 945 PGERGPNGPQGPTGFPGPKGPPG-PPGKDGLPGH---PGQRGETGFQGKTGPPGPP--GV 998 Query: 567 AAAADPNAAWAAYYSHYYQQPPGP-----VPGPA--------PAPAAPPAQGEPP----- 608 P + PPGP +PG A P PA P + PP Sbjct: 999 VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGF 1058 Query: 609 -----QPPPTGQSDYTKAWEEYYKKIGQQPQQ-PGAPPQQDYTKAWEEYYKKQAQVATGG 662 P P G +G + + P PP + + G Sbjct: 1059 PGDRGLPGPVG-------------ALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105 Query: 663 --GPGAPPGSQPDYSAAWAEYYRQQAAYYG-----QTPGPGGPQPPPTQQGQQ 708 GP PPG + A + + A G PGP GP PP + G + Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDK 1158 Score = 64.7 bits (156), Expect = 3e-10 Identities = 188/746 (25%), Positives = 228/746 (30%), Gaps = 165/746 (22%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPPGGGGPG 68 PGP P G GG G G P GP G +G GP G G G + G PG GP Sbjct: 570 PGPVGPPGSGGLKGEPGDVGPQGPRGV--QGPPGPAGKPGRRGRAGSDGARGMPGQTGP- 626 Query: 69 IRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGD 128 + D D + G + D G E GD E G+ Sbjct: 627 -KGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDG--------ERGDDGEVGPRGLPGE 677 Query: 129 -SISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKV--QISPDSG 185 LGP PP P G+ G+ G+ G + N Q Q +P + Sbjct: 678 PGPRGLLGPKGPPGPPG-------PPGVTGMD-GQPGPKGNVGPQGEPGPPGQQGNPGAQ 729 Query: 186 GLPERSVSLTGAPESVQKAKMMLDDIVSR-------GRGGPPGQFHDNANGGQNGTVQEI 238 GLP ++ E K L + G+ GPPG+ G G Sbjct: 730 GLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQG----- 784 Query: 239 MIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEM 298 P G G KG + I+ L+ G K +DG D ++ Sbjct: 785 --PIGYPGPRGVKGADGIRGLKGTKGEKG---EDGFPGFKGDMGIK-------------- 825 Query: 299 VMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQF 358 GDR E G G D P G G G + Sbjct: 826 -------------GDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPL-------------- 858 Query: 359 KQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQG 418 GP +G P + R GP G G PG P G G G+G Sbjct: 859 ------GPPGEKGKLGVPGLPGYPGR----------QGPKGSIGFPGFP-GANGEKGGRG 901 Query: 419 NWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLP-----------PN 467 G PG P + G RG + I + G P P Sbjct: 902 TPGKPG-------PRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQ 954 Query: 468 GDPNFKLFIIRGSPQQID----HAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPF 523 G F P D H Q E +G P GP PG GP GP G GP Sbjct: 955 GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP-PGVVGPQGPTG--ETGPM 1011 Query: 524 NQ-GPPGAPPHAGGPPPHQYPPQGWGNTYPQWQP-----PAPHDPSKAAAAAADPNAAW- 576 + G PG P GPP Q P G + P P P D Sbjct: 1012 GERGHPGPP----GPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP 1067 Query: 577 -AAYYSHYYQQPPGPVPGPA-------PAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKK 628 A + PPGP PGPA PA AA P G P +P P G +K Sbjct: 1068 VGALGLKGNEGPPGP-PGPAGSPGERGPAGAAGPI-GIPGRPGPQGPPGPAG------EK 1119 Query: 629 IGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG--GPGAPPGSQPDYSAAWAEYYRQQA 686 + P P +D Q V G GP PPG D + Sbjct: 1120 GAPGEKGPQGPAGRDGL---------QGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSK 1170 Query: 687 AYYGQT--PGPGGPQPPPTQQGQQQA 710 G+ PGP GPQ P Q G A Sbjct: 1171 GDKGEQGPPGPTGPQGPIGQPGPSGA 1196 Score = 57.4 bits (137), Expect = 5e-08 Identities = 78/252 (30%), Positives = 89/252 (35%), Gaps = 54/252 (21%) Query: 396 GPPGPPGGPGM-----PPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVK 448 G PGPPG PG PPG +G G G PG GE S P K G G E + Sbjct: 1345 GDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQ 1404 Query: 449 AINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG--P 506 + GA E + PP G P + + G PVG P Sbjct: 1405 G---EKGAKGEAGLEGPPGKTGPIGPQGAPGKPGP---------DGLRGIPGPVGEQGLP 1452 Query: 507 GGPGPAGPMGPFNPGPF-----NQGPPGAPPHAG-----GPPPHQYP------PQGWGNT 550 G PGP GP GP P + GP G H G GPP Q P G++ Sbjct: 1453 GSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSS 1512 Query: 551 YPQWQ-----PPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAA 600 P+ + P P P P A S P GP PGP P P Sbjct: 1513 GPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSS----GPTGPKGEAGHPGP-PGPPG 1567 Query: 601 PPAQGEPPQPPP 612 PP GE QP P Sbjct: 1568 PP--GEVIQPLP 1577 Score = 53.9 bits (128), Expect = 5e-07 Identities = 80/327 (24%), Positives = 97/327 (29%), Gaps = 60/327 (18%) Query: 393 LRSGPPGPPGGPGMP-PGGRGRGRGQ----GNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447 L GPPGP G G+P P G GQ G GPPG G Sbjct: 466 LIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRP----------------GLPGA 509 Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPG 507 + G + + + GD K ++ Q Q + GP P+G G Sbjct: 510 DGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGL-TG 568 Query: 508 GPGPAGP--MGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKA 565 PGP GP G P + GP G P GPP P G P Sbjct: 569 RPGPVGPPGSGGLKGEPGDVGPQG-PRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPK 627 Query: 566 AAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE------PPQPPPTGQSDYT 619 D A H P PGP GE P +P P G Sbjct: 628 GDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLG-- 685 Query: 620 KAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWA 679 P+ P PP + + V G PG PPG Q + A Sbjct: 686 -------------PKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPG-PPGQQGNPGAQ-- 729 Query: 680 EYYRQQAAYYGQTPGPGGPQPPPTQQG 706 PGP G PP ++G Sbjct: 730 -----------GLPGPQGAIGPPGEKG 745 Score = 48.1 bits (113), Expect = 3e-05 Identities = 69/260 (26%), Positives = 91/260 (35%), Gaps = 38/260 (14%) Query: 5 STGGPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGG-----GGPGGGSAGG 57 + G P P GPP G G G G PGPPG G G GP G G PG + G Sbjct: 1319 AAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPG 1378 Query: 58 PSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAAT--TVNNSTPDFGFGGQKRQLEDG 115 P+ PG GP ++ A RQ G+A + P G + DG Sbjct: 1379 PTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDG 1438 Query: 116 DQPESKKLASQG----DSISSQLGPIHPPPRTSMTEE-----YRVPDGMVGLIIGRGGEQ 166 + + QG GP+ PP + + + G++GL IG GEQ Sbjct: 1439 LRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGL-IGPPGEQ 1497 Query: 167 INKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDN 226 K G + P P+ +TG + G GPPG Sbjct: 1498 GEK-----GDRGLPGPQGSSGPKGEQGITGPSGPIGPPG-------PPGLPGPPGPKGAK 1545 Query: 227 ANGGQNGTVQEIMIPAGKAG 246 + G G P G+AG Sbjct: 1546 GSSGPTG-------PKGEAG 1558 Score = 40.0 bits (92), Expect = 0.007 Identities = 29/71 (40%), Positives = 30/71 (42%), Gaps = 10/71 (14%) Query: 6 TGGPPP----GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPS 59 TG P P GP P G G G G PPGPPG G PG G G G G Sbjct: 990 TGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQ----GLPGLAGKEGTKGDPGPAG 1045 Query: 60 QPPGGGGPGIR 70 P G PG+R Sbjct: 1046 LPGKDGPPGLR 1056 Score = 36.2 bits (82), Expect = 0.11 Identities = 29/76 (38%), Positives = 29/76 (38%), Gaps = 15/76 (19%) Query: 7 GGPPPGPPPPAG--GGGGAGGAGG-----------GPPPGPPGAGDRGGGGPGG--GGPG 51 G PPGP P G G G GA G G P GD G G G G PG Sbjct: 776 GQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPG 835 Query: 52 GGSAGGPSQPPGGGGP 67 GP P G GGP Sbjct: 836 PRGEDGPEGPKGRGGP 851 Score = 35.8 bits (81), Expect = 0.14 Identities = 22/54 (40%), Positives = 22/54 (40%), Gaps = 12/54 (22%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 PPGPP G G G G P GP G G PG GP G PPG Sbjct: 1529 PPGPPGLPGPPGPKGAKGSSGPTGPKGE----AGHPGPPGPPG--------PPG 1570 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 85.1 bits (209), Expect = 2e-16 Identities = 94/333 (28%), Positives = 115/333 (34%), Gaps = 66/333 (19%) Query: 396 GPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTG 455 GPP PPG P PP +G + QG PPG G + N+ G Sbjct: 49 GPPSPPGKPQGPPP-QGGNQPQGPPPPPGKPQ----------------GPPPQGGNKPQG 91 Query: 456 AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPM 515 PP G P +G P Q D K P P G P GP P G Sbjct: 92 P--------PPPGKP-------QGPPPQGD--------KSRSPRSPPGK-PQGPPPQGGN 127 Query: 516 GPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAA 575 P P P G P PP GG P PP G PQ PP + S+++ + Sbjct: 128 QPQGPPP-PPGKPQGPPPQGGNKPQGPPPPG----KPQGPPPQGDNKSRSSRSPPGKPQG 182 Query: 576 WAAYYSHYYQQPP-------GPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYK- 627 + Q PP GP P P PP G+P PPP G + A K Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP 242 Query: 628 -----KIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYY 682 + G QPQ P PP + + K Q G G PP ++ + Sbjct: 243 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPG 302 Query: 683 RQQA-------AYYGQTPGPGGPQPPPTQQGQQ 708 + Q G P PG PQ PP Q G + Sbjct: 303 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 335 Score = 77.8 bits (190), Expect = 3e-14 Identities = 101/347 (29%), Positives = 122/347 (35%), Gaps = 102/347 (29%) Query: 365 GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPG 424 GP GPP + ++ +R S RS PPG P GP PP G + +G PP Sbjct: 152 GPPPPGKPQGPPPQGDNKSR-------SSRS-PPGKPQGP--PPQGGNQPQGPP---PPP 198 Query: 425 GEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQI 484 G+ P +GG N+ G PP G P +G P Q Sbjct: 199 GKPQGPPP---------QGG------NKPQGP--------PPPGKP-------QGPPPQG 228 Query: 485 DHAKQLIEEKIEGPLCPVGPGP-GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYP 543 D+ Q P P GP P GG P GP P G P PP GG P P Sbjct: 229 DNKSQSARSP---PGKPQGPPPQGGNQPQGPPPP-------PGKPQGPPPQGGNKPQGPP 278 Query: 544 PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQ-----PPGPVPGPAPA- 597 P G + Q P P SK+ ++ + P Q PPG GP P Sbjct: 279 PPG------KPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 332 Query: 598 ---PAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKK 654 P PP G+P PPP G S A P +P PPQQ+ Sbjct: 333 GNKPQGPPPPGKPQGPPPQGGSKSRSA--------RSPPGKPQGPPQQEGNNP------- 377 Query: 655 QAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPP 701 GP P G P + QA GQ GP P+PP Sbjct: 378 -------QGPPPPAGGNPQ---------QPQAPPAGQPQGP--PRPP 406 Score = 71.6 bits (174), Expect = 2e-12 Identities = 75/232 (32%), Positives = 84/232 (36%), Gaps = 46/232 (19%) Query: 504 PGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAG----GPPPHQYPPQG---WGNTYPQWQP 556 P GG P GP P PG P G PP G GPPP PQG G PQ P Sbjct: 40 PPQGGNKPQGPPSP--PGK----PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 93 Query: 557 P--APHDPSKAAAAAADPNAAWAAYYSHYYQ---QPPGPVP------GPAP----APAAP 601 P P P + P + Q QP GP P GP P P P Sbjct: 94 PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 153 Query: 602 PAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQ---QPGAPPQQDYTKAWEEYYKKQAQV 658 P G+P PPP G + + K G PQ QP PP K Q Sbjct: 154 PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP--------GKPQGPP 205 Query: 659 ATGGG--PGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708 GG G PP +P + Q A ++P PG PQ PP Q G Q Sbjct: 206 PQGGNKPQGPPPPGKPQGPPPQGDNKSQSA----RSP-PGKPQGPPPQGGNQ 252 Score = 62.0 bits (149), Expect = 2e-09 Identities = 59/210 (28%), Positives = 71/210 (33%), Gaps = 46/210 (21%) Query: 519 NPGPFNQGPPGAPPHAG----GPPPHQYPPQG---WGNTYPQWQPPAPHDPSKAAAAAAD 571 +P P GAPP G GPP PQG G PQ PP P P + Sbjct: 28 SPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 87 Query: 572 PNAAWAAYYSHYYQQPPGPVPGPAP------APAAPPAQGEPPQPPPTGQSDYTKAWEEY 625 PPG GP P +P +PP G+P PPP G Sbjct: 88 KPQG---------PPPPGKPQGPPPQGDKSRSPRSPP--GKPQGPPPQG----------- 125 Query: 626 YKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQ 685 G QPQ P PP + + K Q G G PP ++ + + Q Sbjct: 126 ----GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQ 181 Query: 686 A-------AYYGQTPGPGGPQPPPTQQGQQ 708 G P PG PQ PP Q G + Sbjct: 182 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 211 Score = 49.3 bits (116), Expect = 1e-05 Identities = 24/57 (42%), Positives = 25/57 (43%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 G P GPPPP G G GG P GPP G G P GG S P +P G Sbjct: 250 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQG 306 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/77 (38%), Positives = 30/77 (38%), Gaps = 16/77 (20%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGG-------GPGGGSAGGPS 59 G P GPPPP G G GG P GPP G G P GG P G G P Sbjct: 312 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQ 371 Query: 60 Q---------PPGGGGP 67 Q PP GG P Sbjct: 372 QEGNNPQGPPPPAGGNP 388 Score = 47.4 bits (111), Expect = 5e-05 Identities = 29/68 (42%), Positives = 30/68 (44%), Gaps = 12/68 (17%) Query: 8 GPPPGP-----PPPAGGGGGAGGAGGGPPPGPPGAGDRG------GGGPGGGGP-GGGSA 55 GPPP P PPP GG G G P GPP GD+ G P G P GG Sbjct: 70 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 129 Query: 56 GGPSQPPG 63 GP PPG Sbjct: 130 QGPPPPPG 137 Score = 46.6 bits (109), Expect = 8e-05 Identities = 23/57 (40%), Positives = 24/57 (42%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 G P GPPPP G G GG P GPP G G P G S P +P G Sbjct: 126 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182 Score = 46.2 bits (108), Expect = 1e-04 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 9/69 (13%) Query: 8 GPPPGPPPPAGGGGGAGGAGGGPPPGPP---GAGDRGGGGPGGGGPG------GGSAGGP 58 G P GPPP G + + G P GPP G +G P GG P G GP Sbjct: 343 GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 402 Query: 59 SQPPGGGGP 67 +PP GG P Sbjct: 403 PRPPQGGRP 411 Score = 45.8 bits (107), Expect = 1e-04 Identities = 31/74 (41%), Positives = 31/74 (41%), Gaps = 17/74 (22%) Query: 7 GGPPPGPPPPAGGGGGAGGAGG----GPPP-----GPPGAGDRGG-------GGPGGGGP 50 G P GPPPP G G GG GPPP GPP GD G P G P Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP 247 Query: 51 -GGGSAGGPSQPPG 63 GG GP PPG Sbjct: 248 QGGNQPQGPPPPPG 261 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/66 (42%), Positives = 28/66 (42%), Gaps = 11/66 (16%) Query: 9 PPPGPP---PPAGGGGGAGGAGGGPPPGPPGAGDRGG-------GGPGGGGP-GGGSAGG 57 PPPG P PP GG G G P GPP GD G P G P GG G Sbjct: 134 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQG 193 Query: 58 PSQPPG 63 P PPG Sbjct: 194 PPPPPG 199 Score = 44.3 bits (103), Expect = 4e-04 Identities = 43/130 (33%), Positives = 46/130 (35%), Gaps = 21/130 (16%) Query: 2 SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPP-GAGDRGGGGPGGGGPGGGSAGGPSQ 60 S S G P GPPP GG G PPPG P G +GG P G P G P Sbjct: 296 SSRSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQG 347 Query: 61 PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNN---STPDFGFGGQKRQLEDGDQ 117 PP GG R AR K G NN P G Q+ Q Q Sbjct: 348 PPPQGGSKSRS---------ARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 398 Query: 118 PESKKLASQG 127 P+ QG Sbjct: 399 PQGPPRPPQG 408 Score = 43.5 bits (101), Expect = 7e-04 Identities = 30/81 (37%), Positives = 31/81 (38%), Gaps = 25/81 (30%) Query: 8 GPPPGP-----PPPAGGGGGAGGAGGGPPPGPPGAGD------------------RGGGG 44 GPPP P PPP GG G G P GPP GD +GG Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQ 190 Query: 45 PGGGGPGGGSAGGPSQPPGGG 65 P G P G GP PP GG Sbjct: 191 PQGPPPPPGKPQGP--PPQGG 209 Score = 43.5 bits (101), Expect = 7e-04 Identities = 30/81 (37%), Positives = 31/81 (38%), Gaps = 25/81 (30%) Query: 8 GPPPGP-----PPPAGGGGGAGGAGGGPPPGPPGAGD------------------RGGGG 44 GPPP P PPP GG G G P GPP GD +GG Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ 252 Query: 45 PGGGGPGGGSAGGPSQPPGGG 65 P G P G GP PP GG Sbjct: 253 PQGPPPPPGKPQGP--PPQGG 271 Score = 43.1 bits (100), Expect = 9e-04 Identities = 25/60 (41%), Positives = 27/60 (45%), Gaps = 3/60 (5%) Query: 7 GGPPPGPPP-PAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGG 65 G PPPG P P GG + PP P G +GG P G P G GP PP GG Sbjct: 276 GPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGG 333 Score = 42.4 bits (98), Expect = 0.002 Identities = 28/66 (42%), Positives = 29/66 (43%), Gaps = 11/66 (16%) Query: 9 PPPGPP---PPAGGGGGAGGAGGGPPPGPP---GAGDRGGGGPGG--GGP---GGGSAGG 57 PPPG P PP GG G G P GPP G+ R P G GP GG G Sbjct: 258 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG 317 Query: 58 PSQPPG 63 P PPG Sbjct: 318 PPPPPG 323 Score = 42.0 bits (97), Expect = 0.002 Identities = 24/61 (39%), Positives = 25/61 (40%), Gaps = 7/61 (11%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGPPPGPP-------GAGDRGGGGPGGGGPGGGSAGGPS 59 G P GPP P G G GG P GPP G +GG P G P G G P Sbjct: 44 GNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 103 Query: 60 Q 60 Q Sbjct: 104 Q 104 Score = 41.2 bits (95), Expect = 0.003 Identities = 26/62 (41%), Positives = 29/62 (46%), Gaps = 8/62 (12%) Query: 7 GGPPPGP---PPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 G PPPG PPP G + + G P GPP +GG P G P G GP PP Sbjct: 91 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGP--PPQ 145 Query: 64 GG 65 GG Sbjct: 146 GG 147 Score = 41.2 bits (95), Expect = 0.003 Identities = 26/60 (43%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 2 SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPP-GAGDRGGGGPGGGGPGGGSAGGPSQ 60 S S G P GPPP GG G PPPG P G +GG P G P G G P Q Sbjct: 172 SSRSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 227 Score = 41.2 bits (95), Expect = 0.003 Identities = 26/61 (42%), Positives = 26/61 (42%), Gaps = 6/61 (9%) Query: 5 STGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGG 64 S G P GPPP GG G PPPG P GG G P G GP PP G Sbjct: 237 SPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQG 290 Query: 65 G 65 G Sbjct: 291 G 291 Score = 40.8 bits (94), Expect = 0.004 Identities = 26/60 (43%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 2 SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPG-PPGAGDRGGGGPGGGGPGGGSAGGPSQ 60 S S G P GPPP GG G PPPG P G +GG P G P G G P Q Sbjct: 110 SPRSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 165 Score = 37.4 bits (85), Expect = 0.049 Identities = 23/58 (39%), Positives = 25/58 (43%), Gaps = 5/58 (8%) Query: 8 GPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGG 65 G P G PP G + G P GPP +GG P G P G GP PP GG Sbjct: 34 GNPQGAPPQGGNKPQGPPSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGP--PPQGG 86 Score = 37.0 bits (84), Expect = 0.063 Identities = 56/175 (32%), Positives = 63/175 (36%), Gaps = 45/175 (25%) Query: 396 GPPGPPGGP-GMPPGGRGRGRGQGNWGPP------GGEMTFSI--PTHKCGLVIGRGGEN 446 GPP PPG P G PP G + +G G P GG + S P K +GG Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG-- 312 Query: 447 VKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE--KIEGP------ 498 NQ G PP G P +G P Q + Q K +GP Sbjct: 313 ----NQPQGP-------PPPPGKP-------QGPPPQGGNKPQGPPPPGKPQGPPPQGGS 354 Query: 499 -----LCPVGPGPGGPGPAG--PMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQG 546 P G G P G P GP P N P APP AG P PPQG Sbjct: 355 KSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP-AGQPQGPPRPPQG 408 >gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] Length = 371 Score = 85.1 bits (209), Expect = 2e-16 Identities = 93/401 (23%), Positives = 158/401 (39%), Gaps = 90/401 (22%) Query: 138 HPPPRTSMTEEYRVPDG---------------MVGLIIGRGGEQINKIQQDSGCKVQISP 182 HP P+ E +V +G VG IIG+ GE + K++++SG ++ IS Sbjct: 24 HPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINIS- 82 Query: 183 DSGGLPERSVSLTGAPESVQKAKMML-----DDIVSRGRGGPPGQFHDNANGGQNGTVQE 237 G PER V++TG +++ KA M+ +DI++ P + Sbjct: 83 -EGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATS--------KPPVTLR 133 Query: 238 IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACE 297 +++PA + G +IGKGG IK+++E G ++ + D N + ++ + I G P + Q + Sbjct: 134 LVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN-STERAVTISGTPDAIIQCVK 192 Query: 298 MVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQ 357 + ++ E G +P + +G IQ Sbjct: 193 QICVVMLESPP--------------KGATIPYRPKPASTPVIFAGGQAYTIQ-------- 230 Query: 358 FKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--PGGR---- 411 G I H PD+ + L Q P PP G P PG + Sbjct: 231 -------GQYAIPH----PDQ-------LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLH 272 Query: 412 ---------GRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISR 462 G+ G + PP +IP G +IGR G + I Q +GA ++I+ Sbjct: 273 SSEEAQNLMGQSSGL-DASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIAN 331 Query: 463 QLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG 503 + + + I G+P I A+ LI ++ + +G Sbjct: 332 ATEGSSE---RQITITGTPANISLAQYLINARLTSEVTGMG 369 Score = 72.8 bits (177), Expect = 1e-12 Identities = 63/236 (26%), Positives = 99/236 (41%), Gaps = 52/236 (22%) Query: 300 MDILRERDQGGFGDRNEYGSRIG-GGIDVPVPRH------SVGVVIGRSGEMIKKIQNDA 352 + L Q FG R E S++ GG++V + VG +IG+ GE +KK++ ++ Sbjct: 18 LSTLSHHPQPQFGRRME--SKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREES 75 Query: 353 GVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARII-----NDLLQSLRSGPPGPPGGPGMP 407 G RI + G PE+I I GP D A +I D++ S+ + P Sbjct: 76 GARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPAT-------- 125 Query: 408 PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPN 467 P + +P +CG +IG+GG +K I + TGA V+++ + PN Sbjct: 126 -------------SKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN 172 Query: 468 GDPNFKLFIIRGSPQQ-IDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGP 522 + I G+P I KQ+ +E P P G P+ P P Sbjct: 173 STE--RAVTISGTPDAIIQCVKQICVVMLESP------------PKGATIPYRPKP 214 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/105 (30%), Positives = 60/105 (57%), Gaps = 10/105 (9%) Query: 105 FGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGG 164 F G+K L + E++ L Q + + PP + T E +P+ ++G IIGR G Sbjct: 264 FPGEKLPLHSSE--EAQNLMGQSSGLDAS------PPAS--THELTIPNDLIGCIIGRQG 313 Query: 165 EQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLD 209 +IN+I+Q SG +++I+ + G ER +++TG P ++ A+ +++ Sbjct: 314 TKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 358 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 84.3 bits (207), Expect = 3e-16 Identities = 194/731 (26%), Positives = 234/731 (32%), Gaps = 126/731 (17%) Query: 15 PPAGGGGGAGGAGGGPPP----GPPGA-GDRGGGGPGGG-GPGGGSAG-GPSQPPGGGGP 67 P A G GA G G P P GP G G RG GP G GP G S G GP PPG GP Sbjct: 873 PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 932 Query: 68 GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQG 127 + + G D + GF G+ G + QG Sbjct: 933 QGPQGPVGFPGPKGPP--GPPGKDGLPGHPGQRGETGFQGKT-----GPPGPGGVVGPQG 985 Query: 128 DSISSQLGPI----HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQ-QDSGCKVQISP 182 + + GPI HP P E+ +P G G +G I +D ++ P Sbjct: 986 PT--GETGPIGERGHPGPPGPPGEQ-GLP-GAAGKEGAKGDPGPQGISGKDGPAGLRGFP 1041 Query: 183 DSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPA 242 GLP GAP G GPPG G GT I +P Sbjct: 1042 GERGLP----GAQGAPGLKG----------GEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1087 Query: 243 -----GKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKVQQAC 296 G G KG K Q AG +DG Q + P G P + Sbjct: 1088 RPGPQGPPGPAGEKGAPGEKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKG 1141 Query: 297 EMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRI 356 E I +G GD+ E G G+ PV + G G + G+ Sbjct: 1142 E----IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP-----RGQQGMFG 1192 Query: 357 QFKQDDGT-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPG 409 Q K D+G GP + + GPP + GP GPPG PG P G Sbjct: 1193 Q-KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----------GPMGPPGPPG-PRG 1240 Query: 410 GRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGD 469 +G G GPPG + +G GE +A N + P G+ Sbjct: 1241 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGG---PKGE 1289 Query: 470 PNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAG----PMGPFNPGPFNQ 525 RG + +GP GP G PGP G P P PGP Q Sbjct: 1290 --------RGEKGEAGPPGAAGPPGAKGPPGDDGP-KGNPGPVGFPGDPGPPGEPGPAGQ 1340 Query: 526 GPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQ 585 G G P PP G P PP P AA A A + Sbjct: 1341 DGVGGDKGEDGDPGQPGPPGPSGEAGPP-GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1399 Query: 586 QP--PGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQ-PQQPGAPPQQ 642 P GPV GP P +G P P G+ A GQ P P PP Sbjct: 1400 PPGKTGPV-GPQGPAGKPGPEGLRGIPGPVGEQGLPGA-------AGQDGPPGPMGPPGL 1451 Query: 643 DYTKAWEEYYKKQAQVATGGGPG-----APPGSQPDYSAAWAEYYRQQ--AAYYGQTPGP 695 K G PG PPG Q + + A G PGP Sbjct: 1452 PGLKG------DPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1505 Query: 696 GGPQPPPTQQG 706 GP PP G Sbjct: 1506 AGPLGPPGPPG 1516 Score = 80.9 bits (198), Expect = 4e-15 Identities = 180/661 (27%), Positives = 222/661 (33%), Gaps = 109/661 (16%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSAGGPSQPPG-GG 65 PPGP G G G GG PG PGA GDRG G G G G GP PPG G Sbjct: 581 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 640 Query: 66 GPGIRKDAFADAVQRARQIAAKIG-----GDAATTVNNSTPDF----GFGGQKRQLEDGD 116 G+R + D R + + G G T P G G K + G Sbjct: 641 DDGMRGE---DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM--GP 695 Query: 117 QPESKKLASQGD----SISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQ 172 Q E QG+ + GPI PP + G+ GL G + Sbjct: 696 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK----PGLAGLPGADGPPGHPGKEG 751 Query: 173 DSGCKVQISPDSGGLPERSVSLTGAPESVQKA---KMMLDDIVSRGRGGPPGQFHDNANG 229 SG K + P P+ + G P V+ A + + +G G PG D Sbjct: 752 QSGEKGALGPPG---PQGPIGYPG-PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLK 807 Query: 230 GQNGTVQEI--------MIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK 281 G G V +I P G+AG G + + GV + G Q Sbjct: 808 GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----- 862 Query: 282 PLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRS 341 P G P G G E G+R G P PR G R Sbjct: 863 PKGSTGFP-------------------GFPGANGEKGAR--GVAGKPGPRGQRGPTGPRG 901 Query: 342 GEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPP 401 + G + D GP GP GPPGPP Sbjct: 902 SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG----------PKGPPGPP 951 Query: 402 GGPGMP--PGGRGRGRGQGNWGP--PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAF 457 G G+P PG RG QG GP PGG + PT + G + RG + G Sbjct: 952 GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 1011 Query: 458 VEISRQLPPNGDPNFKLFI-------IRGSPQQ-----IDHAKQLI-EEKIEGPLCPVG- 503 ++ GDP + +RG P + A L E +GP PVG Sbjct: 1012 GAAGKE-GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1070 Query: 504 PGP-GGPGPAGPMG-PFNPGPFNQGPPGAPPHAGGPPPHQYP--PQGWGNTYPQWQPPAP 559 PG G G AGP+G P PGP QGPPG P G P + P P G P P Sbjct: 1071 PGERGSAGTAGPIGLPGRPGP--QGPPG-PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1127 Query: 560 HDPSKAAAAAADPN-----AAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTG 614 P+ + D + PPGP PG AP G +P P G Sbjct: 1128 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP-PGLQGPVGAPGIAGGDGEPGPRG 1186 Query: 615 Q 615 Q Sbjct: 1187 Q 1187 Score = 73.6 bits (179), Expect = 6e-13 Identities = 192/769 (24%), Positives = 250/769 (32%), Gaps = 154/769 (20%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGG------- 64 GPP PAG G G G P GPPG D G GP G PG A G PPG Sbjct: 454 GPPGPAGPAGIMGPPGLQGPTGPPG--DPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFR 510 Query: 65 -GGPGIR------KDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQ 117 GG G + ++A A A+ + +IA + P G G + E GD Sbjct: 511 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 570 Query: 118 PESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCK 177 QG GP P + G G GRG + + G K Sbjct: 571 GPQGPRGVQGPP-----GPTGKPGKR----------GRPGADGGRG------MPGEPGAK 609 Query: 178 VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQE 237 D GLP G P RG GPPG D+ G++G + Sbjct: 610 GDRGFD--GLP-------GLPGDKGHRG-------ERGPQGPPGPPGDDGMRGEDGEIGP 653 Query: 238 IMIP--AGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK-------------- 281 +P AG GL+ +G AGV G+ + Sbjct: 654 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 713 Query: 282 --PLRIIGDPYKVQQACEMVMDILRERD--QGGFGDRNEYGSRIGGGIDVPVPRHSVGVV 337 P IG P + + + L D G G + G + G + P P+ +G Sbjct: 714 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK--GALGPPGPQGPIGYP 771 Query: 338 IGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGP 397 R + ++ G + + +D G + + G DR E + + GP Sbjct: 772 GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG--DRGE-----VGQIGPRGEDGP 824 Query: 398 PGPPG--GPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKAI 450 GP G GP PG G+ +G G PG G T G G + + + Sbjct: 825 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 884 Query: 451 NQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPG 510 + G Q P G RGS + + G P GP PG G Sbjct: 885 AGKPGP----RGQRGPTGP--------RGSRGARGPTGKPGPKGTSGGDGPPGP-PGERG 931 Query: 511 PAGPMGPFN-PGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQ--PPAPHDPSKAAA 567 P GP GP PGP +GPPG PP G P H P G T Q + PP P Sbjct: 932 PQGPQGPVGFPGP--KGPPG-PPGKDGLPGH---PGQRGETGFQGKTGPPGPG----GVV 981 Query: 568 AAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSD---------- 617 P + PPGP PG P A +G P P G S Sbjct: 982 GPQGPTGETGPIGERGHPGPPGP-PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 1040 Query: 618 -----YTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG--------GP 664 A K G+ PQ P P ++ T G GP Sbjct: 1041 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSP---------GERGSAGTAGPIGLPGRPGP 1091 Query: 665 GAPPGSQPDYSAAWAEYYRQQAAYYGQT-----PGPGGPQPPPTQQGQQ 708 PPG + A + + A G PGP GP P + G + Sbjct: 1092 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1140 Score = 71.2 bits (173), Expect = 3e-12 Identities = 182/691 (26%), Positives = 226/691 (32%), Gaps = 113/691 (16%) Query: 5 STGGPPPGPP---PPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGGPGG--GGPGG 52 S G PPGPP P G G G G PPGPPG G RG G G G PG Sbjct: 918 SGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP 977 Query: 53 GSAGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQ 111 G GP P G GP G R + + G + A G G+ Sbjct: 978 GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA---KGDPGPQGISGKDGP 1034 Query: 112 LEDGDQPESKKL--ASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLI--IGRGGEQ- 166 P + L A + GP PP E R G G I GR G Q Sbjct: 1035 AGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE-RGSAGTAGPIGLPGRPGPQG 1093 Query: 167 INKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDN 226 + G + P + G P A +D +G G PGQ Sbjct: 1094 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED-GDKGEIGEPGQKGSK 1152 Query: 227 ANGGQNGT--VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPL 283 + G+NG + P G G+ G G + Q G K +G++ P+ Sbjct: 1153 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG---DEGARGFPGPPGPI 1209 Query: 284 RIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSVGVV--IGR 340 + G P + E D+ G G R G G D P P SVG V +G Sbjct: 1210 GLQGLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGP---NGADGPQGPPGSVGSVGGVGE 1265 Query: 341 SGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPP-DRCEHAARIINDLLQSLRSGPPG 399 GE +AG GP A + GP +R E +GPPG Sbjct: 1266 KGE-----PGEAG---------NPGPPGEAGVGGPKGERGEKG-----------EAGPPG 1300 Query: 400 PPGGPGM--PPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQTG 455 G PG PPG G G G PG G P + G+ +G + G Sbjct: 1301 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1360 Query: 456 AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPM 515 S + P G P RG P + E+ +G GP PG GP GP Sbjct: 1361 P----SGEAGPPGPPG-----KRGPPGAAGAEGRQGEKGAKGEAGAEGP-PGKTGPVGPQ 1410 Query: 516 GPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNA 574 GP PGP +G G P GP Q P G Q PP P P DP + Sbjct: 1411 GPAGKPGP--EGLRGIP----GPVGEQGLPGAAG----QDGPPGPMGPPGLPGLKGDPGS 1460 Query: 575 AWAAYYSHYYQ--QPPGP-----------------------VPGPAPAPAAPPAQGEP-P 608 + PPG +PGPA P G P P Sbjct: 1461 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP 1520 Query: 609 QPPPTGQSDYTKAWEEYYKKIGQQPQQPGAP 639 Q P + A ++ + P PG P Sbjct: 1521 QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1551 Score = 70.5 bits (171), Expect = 5e-12 Identities = 96/337 (28%), Positives = 116/337 (34%), Gaps = 67/337 (19%) Query: 396 GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447 GP GP G PG PG +G +G GPPG P G+ GG+ Sbjct: 1126 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP-GLQGPVGAPGIA---GGDGE 1181 Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE-GPLCPVGPGP 506 Q G F + GD + F P + EK E G + P+GP P Sbjct: 1182 PGPRGQQGMFGQ-------KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP-P 1233 Query: 507 GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPA--PHDPSK 564 G PGP GP GP N QGPPG+ GG P + GN P + P Sbjct: 1234 GPPGPRGPQGP-NGADGPQGPPGSVGSVGGVGEKGEPGEA-GNPGPPGEAGVGGPKGERG 1291 Query: 565 AAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAPPAQGEPPQPPPTGQSDYT 619 A P AA + PPG PGP P P G P +P P GQ Sbjct: 1292 EKGEAGPPGAAGPPGA----KGPPGDDGPKGNPGPVGFPGDP---GPPGEPGPAGQDGVG 1344 Query: 620 KAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWA 679 E P QPG P GP PPG + AA A Sbjct: 1345 GDKGE-----DGDPGQPGPPGPSGEA-----------------GPPGPPGKRGPPGAAGA 1382 Query: 680 EYYRQQAAYYGQT--------PGPGGPQPPPTQQGQQ 708 E + + G+ GP GPQ P + G + Sbjct: 1383 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE 1419 Score = 60.1 bits (144), Expect = 7e-09 Identities = 90/355 (25%), Positives = 122/355 (34%), Gaps = 70/355 (19%) Query: 396 GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447 GP G PG G+P PG G+ +G GPPG + P + G+ +G + V Sbjct: 727 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPR-GV---KGADGV 782 Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFI-IRGSPQQIDHAKQLIEEKIEGPLCPVGPGP 506 + + G E +G P FK + ++G ++ E+ EGP GP Sbjct: 783 RGLKGSKGEKGE-------DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP-T 834 Query: 507 GGPGPAGPMG-------PFNPG-PFNQGPPGAPPHAGGP----------------PPHQY 542 G PGP+G G P PG P QGP G+ G P P Q Sbjct: 835 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 894 Query: 543 PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV--PGPAPAPAA 600 P G + P P + P Q P GPV PGP P Sbjct: 895 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG----ERGPQGPQGPVGFPGPKGPPGP 950 Query: 601 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT 660 P G P P G++ + Q PP + + + Sbjct: 951 PGKDGLPGHPGQRGETGF---------------QGKTGPPGPGGVVGPQGPTGETGPIGE 995 Query: 661 GG--GPGAPPGSQPDYSAAWAEYYRQQAAYYGQT--PGPGGPQPPPTQQGQQQAQ 711 G GP PPG Q AA E + G + GP G + P ++G AQ Sbjct: 996 RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 1050 Score = 56.6 bits (135), Expect = 8e-08 Identities = 68/235 (28%), Positives = 85/235 (36%), Gaps = 62/235 (26%) Query: 495 IEGPLCPVGPGP--GGPGPAGPMGPFNPG-PFNQGPPGAPPHAG-----GPP------PH 540 +EGP P GP G PG GP GP PG P ++GPPG P G GPP P Sbjct: 452 VEGPPGPAGPAGIMGPPGLQGPTGP--PGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPF 509 Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPA 595 +Y G P ++ A A A A A + PPGP+ PGP Sbjct: 510 RYGGDG---------SKGPTISAQEAQAQAILQQARIAL-----RGPPGPMGLTGRPGPV 555 Query: 596 PAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQ 655 P + A+GE P P G Q P P P K+ Sbjct: 556 GGPGSSGAKGESGDPGPQGPRGV------------QGPPGPTGKP------------GKR 591 Query: 656 AQVATGGGPGAP--PGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708 + GG G P PG++ D + G+ GP GP PP G + Sbjct: 592 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER-GPQGPPGPPGDDGMR 645 Score = 50.4 bits (119), Expect = 6e-06 Identities = 87/325 (26%), Positives = 110/325 (33%), Gaps = 55/325 (16%) Query: 393 LRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGG-ENVKA 449 L GPPGP G G+ PPG QG GPPG P GR G Sbjct: 451 LVEGPPGPAGPAGIMGPPGL------QGPTGPPGDPGDRGPP--------GRPGLPGADG 496 Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG----PG 505 + G + + + +G K I Q Q + GP P+G PG Sbjct: 497 LPGPPGTMLMLPFRYGGDGS---KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG 553 Query: 506 P-GGPGPAGPMGPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPS 563 P GGPG +G G +PGP QGP G GPP P G P +P Sbjct: 554 PVGGPGSSGAKGESGDPGP--QGPRGVQ----GPPGPTGKPGKRGRPGADGGRGMPGEPG 607 Query: 564 KAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWE 623 D H ++ P PGP P +GE + P G E Sbjct: 608 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGP---PGDDGMRGEDGEIGPRGLPG-----E 659 Query: 624 EYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYR 683 + + PGAP Q + + + G PG PPG Q + Sbjct: 660 AGPRGLLGPRGTPGAPGQPGMAGV-DGPPGPKGNMGPQGEPG-PPGQQGNPGPQ------ 711 Query: 684 QQAAYYGQTPGPGGPQPPPTQQGQQ 708 PGP GP PP ++G Q Sbjct: 712 -------GLPGPQGPIGPPGEKGPQ 729 Score = 43.5 bits (101), Expect = 7e-04 Identities = 27/61 (44%), Positives = 28/61 (45%), Gaps = 4/61 (6%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGGGGP 67 G P G GG G AG PPGPPG G G G GP G G +G P P G P Sbjct: 1492 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1551 Query: 68 G 68 G Sbjct: 1552 G 1552 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 11/78 (14%) Query: 3 DYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGA-------GDRGGGGPGG--GGPGGG 53 D G P P PP G G AG G GPPGA G++G G G G PG Sbjct: 1346 DKGEDGDPGQPGPP-GPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1404 Query: 54 SAGGPSQPPGGGGP-GIR 70 GP P G GP G+R Sbjct: 1405 GPVGPQGPAGKPGPEGLR 1422 Score = 39.7 bits (91), Expect = 0.010 Identities = 53/169 (31%), Positives = 65/169 (38%), Gaps = 37/169 (21%) Query: 8 GPPPGPPPPA--GGGGGAGGAGGGPPPGPPG-AGDRG----GGGPGGGGPGG-----GSA 55 GP P PP G G G G P GPPG G +G G PG GP G G + Sbjct: 694 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 753 Query: 56 G-----GPSQPPGG-GGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQK 109 G GP P G G PG R AD V+ + + G D GF G K Sbjct: 754 GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED------------GFPGFK 801 Query: 110 RQLE-DGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVG 157 + GD+ E ++ +G+ GP P R T + P G G Sbjct: 802 GDMGLKGDRGEVGQIGPRGED-----GPEGPKGRAGPTGD-PGPSGQAG 844 Score = 32.3 bits (72), Expect = 1.6 Identities = 20/44 (45%), Positives = 20/44 (45%), Gaps = 3/44 (6%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRG-GGGPGGGGPGG 52 PPGPP G G G G P G GD G G PG GP G Sbjct: 1511 PPGPPGLPGPQGPKGNKGSTGPAGQ--KGDSGLPGPPGSPGPPG 1552 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 84.3 bits (207), Expect = 3e-16 Identities = 194/731 (26%), Positives = 234/731 (32%), Gaps = 126/731 (17%) Query: 15 PPAGGGGGAGGAGGGPPP----GPPGA-GDRGGGGPGGG-GPGGGSAG-GPSQPPGGGGP 67 P A G GA G G P P GP G G RG GP G GP G S G GP PPG GP Sbjct: 822 PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 881 Query: 68 GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQG 127 + + G D + GF G+ G + QG Sbjct: 882 QGPQGPVGFPGPKGPP--GPPGKDGLPGHPGQRGETGFQGKT-----GPPGPGGVVGPQG 934 Query: 128 DSISSQLGPI----HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQ-QDSGCKVQISP 182 + + GPI HP P E+ +P G G +G I +D ++ P Sbjct: 935 PT--GETGPIGERGHPGPPGPPGEQ-GLP-GAAGKEGAKGDPGPQGISGKDGPAGLRGFP 990 Query: 183 DSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPA 242 GLP GAP G GPPG G GT I +P Sbjct: 991 GERGLP----GAQGAPGLKG----------GEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1036 Query: 243 -----GKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKVQQAC 296 G G KG K Q AG +DG Q + P G P + Sbjct: 1037 RPGPQGPPGPAGEKGAPGEKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKG 1090 Query: 297 EMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRI 356 E I +G GD+ E G G+ PV + G G + G+ Sbjct: 1091 E----IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP-----RGQQGMFG 1141 Query: 357 QFKQDDGT-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPG 409 Q K D+G GP + + GPP + GP GPPG PG P G Sbjct: 1142 Q-KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----------GPMGPPGPPG-PRG 1189 Query: 410 GRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGD 469 +G G GPPG + +G GE +A N + P G+ Sbjct: 1190 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGG---PKGE 1238 Query: 470 PNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAG----PMGPFNPGPFNQ 525 RG + +GP GP G PGP G P P PGP Q Sbjct: 1239 --------RGEKGEAGPPGAAGPPGAKGPPGDDGP-KGNPGPVGFPGDPGPPGEPGPAGQ 1289 Query: 526 GPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQ 585 G G P PP G P PP P AA A A + Sbjct: 1290 DGVGGDKGEDGDPGQPGPPGPSGEAGPP-GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1348 Query: 586 QP--PGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQ-PQQPGAPPQQ 642 P GPV GP P +G P P G+ A GQ P P PP Sbjct: 1349 PPGKTGPV-GPQGPAGKPGPEGLRGIPGPVGEQGLPGA-------AGQDGPPGPMGPPGL 1400 Query: 643 DYTKAWEEYYKKQAQVATGGGPG-----APPGSQPDYSAAWAEYYRQQ--AAYYGQTPGP 695 K G PG PPG Q + + A G PGP Sbjct: 1401 PGLKG------DPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1454 Query: 696 GGPQPPPTQQG 706 GP PP G Sbjct: 1455 AGPLGPPGPPG 1465 Score = 80.9 bits (198), Expect = 4e-15 Identities = 180/661 (27%), Positives = 222/661 (33%), Gaps = 109/661 (16%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSAGGPSQPPG-GG 65 PPGP G G G GG PG PGA GDRG G G G G GP PPG G Sbjct: 530 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 589 Query: 66 GPGIRKDAFADAVQRARQIAAKIG-----GDAATTVNNSTPDF----GFGGQKRQLEDGD 116 G+R + D R + + G G T P G G K + G Sbjct: 590 DDGMRGE---DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM--GP 644 Query: 117 QPESKKLASQGD----SISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQ 172 Q E QG+ + GPI PP + G+ GL G + Sbjct: 645 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK----PGLAGLPGADGPPGHPGKEG 700 Query: 173 DSGCKVQISPDSGGLPERSVSLTGAPESVQKA---KMMLDDIVSRGRGGPPGQFHDNANG 229 SG K + P P+ + G P V+ A + + +G G PG D Sbjct: 701 QSGEKGALGPPG---PQGPIGYPG-PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLK 756 Query: 230 GQNGTVQEI--------MIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK 281 G G V +I P G+AG G + + GV + G Q Sbjct: 757 GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----- 811 Query: 282 PLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRS 341 P G P G G E G+R G P PR G R Sbjct: 812 PKGSTGFP-------------------GFPGANGEKGAR--GVAGKPGPRGQRGPTGPRG 850 Query: 342 GEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPP 401 + G + D GP GP GPPGPP Sbjct: 851 SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG----------PKGPPGPP 900 Query: 402 GGPGMP--PGGRGRGRGQGNWGP--PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAF 457 G G+P PG RG QG GP PGG + PT + G + RG + G Sbjct: 901 GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 960 Query: 458 VEISRQLPPNGDPNFKLFI-------IRGSPQQ-----IDHAKQLI-EEKIEGPLCPVG- 503 ++ GDP + +RG P + A L E +GP PVG Sbjct: 961 GAAGKE-GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1019 Query: 504 PGP-GGPGPAGPMG-PFNPGPFNQGPPGAPPHAGGPPPHQYP--PQGWGNTYPQWQPPAP 559 PG G G AGP+G P PGP QGPPG P G P + P P G P P Sbjct: 1020 PGERGSAGTAGPIGLPGRPGP--QGPPG-PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1076 Query: 560 HDPSKAAAAAADPN-----AAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTG 614 P+ + D + PPGP PG AP G +P P G Sbjct: 1077 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP-PGLQGPVGAPGIAGGDGEPGPRG 1135 Query: 615 Q 615 Q Sbjct: 1136 Q 1136 Score = 73.6 bits (179), Expect = 6e-13 Identities = 192/769 (24%), Positives = 250/769 (32%), Gaps = 154/769 (20%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGG------- 64 GPP PAG G G G P GPPG D G GP G PG A G PPG Sbjct: 403 GPPGPAGPAGIMGPPGLQGPTGPPG--DPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFR 459 Query: 65 -GGPGIR------KDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQ 117 GG G + ++A A A+ + +IA + P G G + E GD Sbjct: 460 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 519 Query: 118 PESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCK 177 QG GP P + G G GRG + + G K Sbjct: 520 GPQGPRGVQGPP-----GPTGKPGKR----------GRPGADGGRG------MPGEPGAK 558 Query: 178 VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQE 237 D GLP G P RG GPPG D+ G++G + Sbjct: 559 GDRGFD--GLP-------GLPGDKGHRG-------ERGPQGPPGPPGDDGMRGEDGEIGP 602 Query: 238 IMIP--AGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK-------------- 281 +P AG GL+ +G AGV G+ + Sbjct: 603 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 662 Query: 282 --PLRIIGDPYKVQQACEMVMDILRERD--QGGFGDRNEYGSRIGGGIDVPVPRHSVGVV 337 P IG P + + + L D G G + G + G + P P+ +G Sbjct: 663 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK--GALGPPGPQGPIGYP 720 Query: 338 IGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGP 397 R + ++ G + + +D G + + G DR E + + GP Sbjct: 721 GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG--DRGE-----VGQIGPRGEDGP 773 Query: 398 PGPPG--GPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKAI 450 GP G GP PG G+ +G G PG G T G G + + + Sbjct: 774 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 833 Query: 451 NQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPG 510 + G Q P G RGS + + G P GP PG G Sbjct: 834 AGKPGP----RGQRGPTGP--------RGSRGARGPTGKPGPKGTSGGDGPPGP-PGERG 880 Query: 511 PAGPMGPFN-PGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQ--PPAPHDPSKAAA 567 P GP GP PGP +GPPG PP G P H P G T Q + PP P Sbjct: 881 PQGPQGPVGFPGP--KGPPG-PPGKDGLPGH---PGQRGETGFQGKTGPPGPG----GVV 930 Query: 568 AAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSD---------- 617 P + PPGP PG P A +G P P G S Sbjct: 931 GPQGPTGETGPIGERGHPGPPGP-PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 989 Query: 618 -----YTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG--------GP 664 A K G+ PQ P P ++ T G GP Sbjct: 990 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSP---------GERGSAGTAGPIGLPGRPGP 1040 Query: 665 GAPPGSQPDYSAAWAEYYRQQAAYYGQT-----PGPGGPQPPPTQQGQQ 708 PPG + A + + A G PGP GP P + G + Sbjct: 1041 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089 Score = 71.2 bits (173), Expect = 3e-12 Identities = 182/691 (26%), Positives = 226/691 (32%), Gaps = 113/691 (16%) Query: 5 STGGPPPGPP---PPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGGPGG--GGPGG 52 S G PPGPP P G G G G PPGPPG G RG G G G PG Sbjct: 867 SGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP 926 Query: 53 GSAGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQ 111 G GP P G GP G R + + G + A G G+ Sbjct: 927 GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA---KGDPGPQGISGKDGP 983 Query: 112 LEDGDQPESKKL--ASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLI--IGRGGEQ- 166 P + L A + GP PP E R G G I GR G Q Sbjct: 984 AGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE-RGSAGTAGPIGLPGRPGPQG 1042 Query: 167 INKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDN 226 + G + P + G P A +D +G G PGQ Sbjct: 1043 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED-GDKGEIGEPGQKGSK 1101 Query: 227 ANGGQNGT--VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPL 283 + G+NG + P G G+ G G + Q G K +G++ P+ Sbjct: 1102 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG---DEGARGFPGPPGPI 1158 Query: 284 RIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSVGVV--IGR 340 + G P + E D+ G G R G G D P P SVG V +G Sbjct: 1159 GLQGLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGP---NGADGPQGPPGSVGSVGGVGE 1214 Query: 341 SGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPP-DRCEHAARIINDLLQSLRSGPPG 399 GE +AG GP A + GP +R E +GPPG Sbjct: 1215 KGE-----PGEAG---------NPGPPGEAGVGGPKGERGEKG-----------EAGPPG 1249 Query: 400 PPGGPGM--PPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQTG 455 G PG PPG G G G PG G P + G+ +G + G Sbjct: 1250 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309 Query: 456 AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPM 515 S + P G P RG P + E+ +G GP PG GP GP Sbjct: 1310 P----SGEAGPPGPPG-----KRGPPGAAGAEGRQGEKGAKGEAGAEGP-PGKTGPVGPQ 1359 Query: 516 GPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNA 574 GP PGP +G G P GP Q P G Q PP P P DP + Sbjct: 1360 GPAGKPGP--EGLRGIP----GPVGEQGLPGAAG----QDGPPGPMGPPGLPGLKGDPGS 1409 Query: 575 AWAAYYSHYYQ--QPPGP-----------------------VPGPAPAPAAPPAQGEP-P 608 + PPG +PGPA P G P P Sbjct: 1410 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP 1469 Query: 609 QPPPTGQSDYTKAWEEYYKKIGQQPQQPGAP 639 Q P + A ++ + P PG P Sbjct: 1470 QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1500 Score = 70.5 bits (171), Expect = 5e-12 Identities = 96/337 (28%), Positives = 116/337 (34%), Gaps = 67/337 (19%) Query: 396 GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447 GP GP G PG PG +G +G GPPG P G+ GG+ Sbjct: 1075 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP-GLQGPVGAPGIA---GGDGE 1130 Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE-GPLCPVGPGP 506 Q G F + GD + F P + EK E G + P+GP P Sbjct: 1131 PGPRGQQGMFGQ-------KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP-P 1182 Query: 507 GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPA--PHDPSK 564 G PGP GP GP N QGPPG+ GG P + GN P + P Sbjct: 1183 GPPGPRGPQGP-NGADGPQGPPGSVGSVGGVGEKGEPGEA-GNPGPPGEAGVGGPKGERG 1240 Query: 565 AAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAPPAQGEPPQPPPTGQSDYT 619 A P AA + PPG PGP P P G P +P P GQ Sbjct: 1241 EKGEAGPPGAAGPPGA----KGPPGDDGPKGNPGPVGFPGDP---GPPGEPGPAGQDGVG 1293 Query: 620 KAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWA 679 E P QPG P GP PPG + AA A Sbjct: 1294 GDKGE-----DGDPGQPGPPGPSGEA-----------------GPPGPPGKRGPPGAAGA 1331 Query: 680 EYYRQQAAYYGQT--------PGPGGPQPPPTQQGQQ 708 E + + G+ GP GPQ P + G + Sbjct: 1332 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE 1368 Score = 60.1 bits (144), Expect = 7e-09 Identities = 90/355 (25%), Positives = 122/355 (34%), Gaps = 70/355 (19%) Query: 396 GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447 GP G PG G+P PG G+ +G GPPG + P + G+ +G + V Sbjct: 676 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPR-GV---KGADGV 731 Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFI-IRGSPQQIDHAKQLIEEKIEGPLCPVGPGP 506 + + G E +G P FK + ++G ++ E+ EGP GP Sbjct: 732 RGLKGSKGEKGE-------DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP-T 783 Query: 507 GGPGPAGPMG-------PFNPG-PFNQGPPGAPPHAGGP----------------PPHQY 542 G PGP+G G P PG P QGP G+ G P P Q Sbjct: 784 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 843 Query: 543 PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV--PGPAPAPAA 600 P G + P P + P Q P GPV PGP P Sbjct: 844 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG----ERGPQGPQGPVGFPGPKGPPGP 899 Query: 601 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT 660 P G P P G++ + Q PP + + + Sbjct: 900 PGKDGLPGHPGQRGETGF---------------QGKTGPPGPGGVVGPQGPTGETGPIGE 944 Query: 661 GG--GPGAPPGSQPDYSAAWAEYYRQQAAYYGQT--PGPGGPQPPPTQQGQQQAQ 711 G GP PPG Q AA E + G + GP G + P ++G AQ Sbjct: 945 RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 999 Score = 56.6 bits (135), Expect = 8e-08 Identities = 68/235 (28%), Positives = 85/235 (36%), Gaps = 62/235 (26%) Query: 495 IEGPLCPVGPGP--GGPGPAGPMGPFNPG-PFNQGPPGAPPHAG-----GPP------PH 540 +EGP P GP G PG GP GP PG P ++GPPG P G GPP P Sbjct: 401 VEGPPGPAGPAGIMGPPGLQGPTGP--PGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPF 458 Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPA 595 +Y G P ++ A A A A A + PPGP+ PGP Sbjct: 459 RYGGDG---------SKGPTISAQEAQAQAILQQARIAL-----RGPPGPMGLTGRPGPV 504 Query: 596 PAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQ 655 P + A+GE P P G Q P P P K+ Sbjct: 505 GGPGSSGAKGESGDPGPQGPRGV------------QGPPGPTGKP------------GKR 540 Query: 656 AQVATGGGPGAP--PGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708 + GG G P PG++ D + G+ GP GP PP G + Sbjct: 541 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER-GPQGPPGPPGDDGMR 594 Score = 50.4 bits (119), Expect = 6e-06 Identities = 87/325 (26%), Positives = 110/325 (33%), Gaps = 55/325 (16%) Query: 393 LRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGG-ENVKA 449 L GPPGP G G+ PPG QG GPPG P GR G Sbjct: 400 LVEGPPGPAGPAGIMGPPGL------QGPTGPPGDPGDRGPP--------GRPGLPGADG 445 Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG----PG 505 + G + + + +G K I Q Q + GP P+G PG Sbjct: 446 LPGPPGTMLMLPFRYGGDGS---KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG 502 Query: 506 P-GGPGPAGPMGPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPS 563 P GGPG +G G +PGP QGP G GPP P G P +P Sbjct: 503 PVGGPGSSGAKGESGDPGP--QGPRGVQ----GPPGPTGKPGKRGRPGADGGRGMPGEPG 556 Query: 564 KAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWE 623 D H ++ P PGP P +GE + P G E Sbjct: 557 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGP---PGDDGMRGEDGEIGPRGLPG-----E 608 Query: 624 EYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYR 683 + + PGAP Q + + + G PG PPG Q + Sbjct: 609 AGPRGLLGPRGTPGAPGQPGMAGV-DGPPGPKGNMGPQGEPG-PPGQQGNPGPQ------ 660 Query: 684 QQAAYYGQTPGPGGPQPPPTQQGQQ 708 PGP GP PP ++G Q Sbjct: 661 -------GLPGPQGPIGPPGEKGPQ 678 Score = 43.5 bits (101), Expect = 7e-04 Identities = 27/61 (44%), Positives = 28/61 (45%), Gaps = 4/61 (6%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGGGGP 67 G P G GG G AG PPGPPG G G G GP G G +G P P G P Sbjct: 1441 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1500 Query: 68 G 68 G Sbjct: 1501 G 1501 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 11/78 (14%) Query: 3 DYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGA-------GDRGGGGPGG--GGPGGG 53 D G P P PP G G AG G GPPGA G++G G G G PG Sbjct: 1295 DKGEDGDPGQPGPP-GPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1353 Query: 54 SAGGPSQPPGGGGP-GIR 70 GP P G GP G+R Sbjct: 1354 GPVGPQGPAGKPGPEGLR 1371 Score = 39.7 bits (91), Expect = 0.010 Identities = 53/169 (31%), Positives = 65/169 (38%), Gaps = 37/169 (21%) Query: 8 GPPPGPPPPA--GGGGGAGGAGGGPPPGPPG-AGDRG----GGGPGGGGPGG-----GSA 55 GP P PP G G G G P GPPG G +G G PG GP G G + Sbjct: 643 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 702 Query: 56 G-----GPSQPPGG-GGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQK 109 G GP P G G PG R AD V+ + + G D GF G K Sbjct: 703 GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED------------GFPGFK 750 Query: 110 RQLE-DGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVG 157 + GD+ E ++ +G+ GP P R T + P G G Sbjct: 751 GDMGLKGDRGEVGQIGPRGED-----GPEGPKGRAGPTGD-PGPSGQAG 793 Score = 32.3 bits (72), Expect = 1.6 Identities = 20/44 (45%), Positives = 20/44 (45%), Gaps = 3/44 (6%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRG-GGGPGGGGPGG 52 PPGPP G G G G P G GD G G PG GP G Sbjct: 1460 PPGPPGLPGPQGPKGNKGSTGPAGQ--KGDSGLPGPPGSPGPPG 1501 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 84.3 bits (207), Expect = 3e-16 Identities = 194/731 (26%), Positives = 234/731 (32%), Gaps = 126/731 (17%) Query: 15 PPAGGGGGAGGAGGGPPP----GPPGA-GDRGGGGPGGG-GPGGGSAG-GPSQPPGGGGP 67 P A G GA G G P P GP G G RG GP G GP G S G GP PPG GP Sbjct: 861 PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 920 Query: 68 GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQG 127 + + G D + GF G+ G + QG Sbjct: 921 QGPQGPVGFPGPKGPP--GPPGKDGLPGHPGQRGETGFQGKT-----GPPGPGGVVGPQG 973 Query: 128 DSISSQLGPI----HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQ-QDSGCKVQISP 182 + + GPI HP P E+ +P G G +G I +D ++ P Sbjct: 974 PT--GETGPIGERGHPGPPGPPGEQ-GLP-GAAGKEGAKGDPGPQGISGKDGPAGLRGFP 1029 Query: 183 DSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPA 242 GLP GAP G GPPG G GT I +P Sbjct: 1030 GERGLP----GAQGAPGLKG----------GEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1075 Query: 243 -----GKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKVQQAC 296 G G KG K Q AG +DG Q + P G P + Sbjct: 1076 RPGPQGPPGPAGEKGAPGEKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKG 1129 Query: 297 EMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRI 356 E I +G GD+ E G G+ PV + G G + G+ Sbjct: 1130 E----IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP-----RGQQGMFG 1180 Query: 357 QFKQDDGT-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPG 409 Q K D+G GP + + GPP + GP GPPG PG P G Sbjct: 1181 Q-KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----------GPMGPPGPPG-PRG 1228 Query: 410 GRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGD 469 +G G GPPG + +G GE +A N + P G+ Sbjct: 1229 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGG---PKGE 1277 Query: 470 PNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAG----PMGPFNPGPFNQ 525 RG + +GP GP G PGP G P P PGP Q Sbjct: 1278 --------RGEKGEAGPPGAAGPPGAKGPPGDDGP-KGNPGPVGFPGDPGPPGEPGPAGQ 1328 Query: 526 GPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQ 585 G G P PP G P PP P AA A A + Sbjct: 1329 DGVGGDKGEDGDPGQPGPPGPSGEAGPP-GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1387 Query: 586 QP--PGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQ-PQQPGAPPQQ 642 P GPV GP P +G P P G+ A GQ P P PP Sbjct: 1388 PPGKTGPV-GPQGPAGKPGPEGLRGIPGPVGEQGLPGA-------AGQDGPPGPMGPPGL 1439 Query: 643 DYTKAWEEYYKKQAQVATGGGPG-----APPGSQPDYSAAWAEYYRQQ--AAYYGQTPGP 695 K G PG PPG Q + + A G PGP Sbjct: 1440 PGLKG------DPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1493 Query: 696 GGPQPPPTQQG 706 GP PP G Sbjct: 1494 AGPLGPPGPPG 1504 Score = 80.9 bits (198), Expect = 4e-15 Identities = 180/661 (27%), Positives = 222/661 (33%), Gaps = 109/661 (16%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSAGGPSQPPG-GG 65 PPGP G G G GG PG PGA GDRG G G G G GP PPG G Sbjct: 569 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 628 Query: 66 GPGIRKDAFADAVQRARQIAAKIG-----GDAATTVNNSTPDF----GFGGQKRQLEDGD 116 G+R + D R + + G G T P G G K + G Sbjct: 629 DDGMRGE---DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM--GP 683 Query: 117 QPESKKLASQGD----SISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQ 172 Q E QG+ + GPI PP + G+ GL G + Sbjct: 684 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK----PGLAGLPGADGPPGHPGKEG 739 Query: 173 DSGCKVQISPDSGGLPERSVSLTGAPESVQKA---KMMLDDIVSRGRGGPPGQFHDNANG 229 SG K + P P+ + G P V+ A + + +G G PG D Sbjct: 740 QSGEKGALGPPG---PQGPIGYPG-PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLK 795 Query: 230 GQNGTVQEI--------MIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK 281 G G V +I P G+AG G + + GV + G Q Sbjct: 796 GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----- 850 Query: 282 PLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRS 341 P G P G G E G+R G P PR G R Sbjct: 851 PKGSTGFP-------------------GFPGANGEKGAR--GVAGKPGPRGQRGPTGPRG 889 Query: 342 GEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPP 401 + G + D GP GP GPPGPP Sbjct: 890 SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG----------PKGPPGPP 939 Query: 402 GGPGMP--PGGRGRGRGQGNWGP--PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAF 457 G G+P PG RG QG GP PGG + PT + G + RG + G Sbjct: 940 GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 999 Query: 458 VEISRQLPPNGDPNFKLFI-------IRGSPQQ-----IDHAKQLI-EEKIEGPLCPVG- 503 ++ GDP + +RG P + A L E +GP PVG Sbjct: 1000 GAAGKE-GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1058 Query: 504 PGP-GGPGPAGPMG-PFNPGPFNQGPPGAPPHAGGPPPHQYP--PQGWGNTYPQWQPPAP 559 PG G G AGP+G P PGP QGPPG P G P + P P G P P Sbjct: 1059 PGERGSAGTAGPIGLPGRPGP--QGPPG-PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1115 Query: 560 HDPSKAAAAAADPN-----AAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTG 614 P+ + D + PPGP PG AP G +P P G Sbjct: 1116 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP-PGLQGPVGAPGIAGGDGEPGPRG 1174 Query: 615 Q 615 Q Sbjct: 1175 Q 1175 Score = 73.6 bits (179), Expect = 6e-13 Identities = 192/769 (24%), Positives = 250/769 (32%), Gaps = 154/769 (20%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGG------- 64 GPP PAG G G G P GPPG D G GP G PG A G PPG Sbjct: 442 GPPGPAGPAGIMGPPGLQGPTGPPG--DPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFR 498 Query: 65 -GGPGIR------KDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQ 117 GG G + ++A A A+ + +IA + P G G + E GD Sbjct: 499 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 558 Query: 118 PESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCK 177 QG GP P + G G GRG + + G K Sbjct: 559 GPQGPRGVQGPP-----GPTGKPGKR----------GRPGADGGRG------MPGEPGAK 597 Query: 178 VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQE 237 D GLP G P RG GPPG D+ G++G + Sbjct: 598 GDRGFD--GLP-------GLPGDKGHRG-------ERGPQGPPGPPGDDGMRGEDGEIGP 641 Query: 238 IMIP--AGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK-------------- 281 +P AG GL+ +G AGV G+ + Sbjct: 642 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 701 Query: 282 --PLRIIGDPYKVQQACEMVMDILRERD--QGGFGDRNEYGSRIGGGIDVPVPRHSVGVV 337 P IG P + + + L D G G + G + G + P P+ +G Sbjct: 702 PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK--GALGPPGPQGPIGYP 759 Query: 338 IGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGP 397 R + ++ G + + +D G + + G DR E + + GP Sbjct: 760 GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG--DRGE-----VGQIGPRGEDGP 812 Query: 398 PGPPG--GPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKAI 450 GP G GP PG G+ +G G PG G T G G + + + Sbjct: 813 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 872 Query: 451 NQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPG 510 + G Q P G RGS + + G P GP PG G Sbjct: 873 AGKPGP----RGQRGPTGP--------RGSRGARGPTGKPGPKGTSGGDGPPGP-PGERG 919 Query: 511 PAGPMGPFN-PGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQ--PPAPHDPSKAAA 567 P GP GP PGP +GPPG PP G P H P G T Q + PP P Sbjct: 920 PQGPQGPVGFPGP--KGPPG-PPGKDGLPGH---PGQRGETGFQGKTGPPGPG----GVV 969 Query: 568 AAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSD---------- 617 P + PPGP PG P A +G P P G S Sbjct: 970 GPQGPTGETGPIGERGHPGPPGP-PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 1028 Query: 618 -----YTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG--------GP 664 A K G+ PQ P P ++ T G GP Sbjct: 1029 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSP---------GERGSAGTAGPIGLPGRPGP 1079 Query: 665 GAPPGSQPDYSAAWAEYYRQQAAYYGQT-----PGPGGPQPPPTQQGQQ 708 PPG + A + + A G PGP GP P + G + Sbjct: 1080 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1128 Score = 71.2 bits (173), Expect = 3e-12 Identities = 182/691 (26%), Positives = 226/691 (32%), Gaps = 113/691 (16%) Query: 5 STGGPPPGPP---PPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGGPGG--GGPGG 52 S G PPGPP P G G G G PPGPPG G RG G G G PG Sbjct: 906 SGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP 965 Query: 53 GSAGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQ 111 G GP P G GP G R + + G + A G G+ Sbjct: 966 GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA---KGDPGPQGISGKDGP 1022 Query: 112 LEDGDQPESKKL--ASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLI--IGRGGEQ- 166 P + L A + GP PP E R G G I GR G Q Sbjct: 1023 AGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE-RGSAGTAGPIGLPGRPGPQG 1081 Query: 167 INKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDN 226 + G + P + G P A +D +G G PGQ Sbjct: 1082 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED-GDKGEIGEPGQKGSK 1140 Query: 227 ANGGQNGT--VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPL 283 + G+NG + P G G+ G G + Q G K +G++ P+ Sbjct: 1141 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG---DEGARGFPGPPGPI 1197 Query: 284 RIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSVGVV--IGR 340 + G P + E D+ G G R G G D P P SVG V +G Sbjct: 1198 GLQGLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGP---NGADGPQGPPGSVGSVGGVGE 1253 Query: 341 SGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPP-DRCEHAARIINDLLQSLRSGPPG 399 GE +AG GP A + GP +R E +GPPG Sbjct: 1254 KGE-----PGEAG---------NPGPPGEAGVGGPKGERGEKG-----------EAGPPG 1288 Query: 400 PPGGPGM--PPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQTG 455 G PG PPG G G G PG G P + G+ +G + G Sbjct: 1289 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348 Query: 456 AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPM 515 S + P G P RG P + E+ +G GP PG GP GP Sbjct: 1349 P----SGEAGPPGPPG-----KRGPPGAAGAEGRQGEKGAKGEAGAEGP-PGKTGPVGPQ 1398 Query: 516 GPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNA 574 GP PGP +G G P GP Q P G Q PP P P DP + Sbjct: 1399 GPAGKPGP--EGLRGIP----GPVGEQGLPGAAG----QDGPPGPMGPPGLPGLKGDPGS 1448 Query: 575 AWAAYYSHYYQ--QPPGP-----------------------VPGPAPAPAAPPAQGEP-P 608 + PPG +PGPA P G P P Sbjct: 1449 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP 1508 Query: 609 QPPPTGQSDYTKAWEEYYKKIGQQPQQPGAP 639 Q P + A ++ + P PG P Sbjct: 1509 QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1539 Score = 70.5 bits (171), Expect = 5e-12 Identities = 96/337 (28%), Positives = 116/337 (34%), Gaps = 67/337 (19%) Query: 396 GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447 GP GP G PG PG +G +G GPPG P G+ GG+ Sbjct: 1114 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP-GLQGPVGAPGIA---GGDGE 1169 Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE-GPLCPVGPGP 506 Q G F + GD + F P + EK E G + P+GP P Sbjct: 1170 PGPRGQQGMFGQ-------KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP-P 1221 Query: 507 GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPA--PHDPSK 564 G PGP GP GP N QGPPG+ GG P + GN P + P Sbjct: 1222 GPPGPRGPQGP-NGADGPQGPPGSVGSVGGVGEKGEPGEA-GNPGPPGEAGVGGPKGERG 1279 Query: 565 AAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAPPAQGEPPQPPPTGQSDYT 619 A P AA + PPG PGP P P G P +P P GQ Sbjct: 1280 EKGEAGPPGAAGPPGA----KGPPGDDGPKGNPGPVGFPGDP---GPPGEPGPAGQDGVG 1332 Query: 620 KAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWA 679 E P QPG P GP PPG + AA A Sbjct: 1333 GDKGE-----DGDPGQPGPPGPSGEA-----------------GPPGPPGKRGPPGAAGA 1370 Query: 680 EYYRQQAAYYGQT--------PGPGGPQPPPTQQGQQ 708 E + + G+ GP GPQ P + G + Sbjct: 1371 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE 1407 Score = 60.1 bits (144), Expect = 7e-09 Identities = 90/355 (25%), Positives = 122/355 (34%), Gaps = 70/355 (19%) Query: 396 GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447 GP G PG G+P PG G+ +G GPPG + P + G+ +G + V Sbjct: 715 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPR-GV---KGADGV 770 Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFI-IRGSPQQIDHAKQLIEEKIEGPLCPVGPGP 506 + + G E +G P FK + ++G ++ E+ EGP GP Sbjct: 771 RGLKGSKGEKGE-------DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP-T 822 Query: 507 GGPGPAGPMG-------PFNPG-PFNQGPPGAPPHAGGP----------------PPHQY 542 G PGP+G G P PG P QGP G+ G P P Q Sbjct: 823 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 882 Query: 543 PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV--PGPAPAPAA 600 P G + P P + P Q P GPV PGP P Sbjct: 883 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG----ERGPQGPQGPVGFPGPKGPPGP 938 Query: 601 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT 660 P G P P G++ + Q PP + + + Sbjct: 939 PGKDGLPGHPGQRGETGF---------------QGKTGPPGPGGVVGPQGPTGETGPIGE 983 Query: 661 GG--GPGAPPGSQPDYSAAWAEYYRQQAAYYGQT--PGPGGPQPPPTQQGQQQAQ 711 G GP PPG Q AA E + G + GP G + P ++G AQ Sbjct: 984 RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 1038 Score = 56.6 bits (135), Expect = 8e-08 Identities = 68/235 (28%), Positives = 85/235 (36%), Gaps = 62/235 (26%) Query: 495 IEGPLCPVGPGP--GGPGPAGPMGPFNPG-PFNQGPPGAPPHAG-----GPP------PH 540 +EGP P GP G PG GP GP PG P ++GPPG P G GPP P Sbjct: 440 VEGPPGPAGPAGIMGPPGLQGPTGP--PGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPF 497 Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPA 595 +Y G P ++ A A A A A + PPGP+ PGP Sbjct: 498 RYGGDG---------SKGPTISAQEAQAQAILQQARIAL-----RGPPGPMGLTGRPGPV 543 Query: 596 PAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQ 655 P + A+GE P P G Q P P P K+ Sbjct: 544 GGPGSSGAKGESGDPGPQGPRGV------------QGPPGPTGKP------------GKR 579 Query: 656 AQVATGGGPGAP--PGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708 + GG G P PG++ D + G+ GP GP PP G + Sbjct: 580 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER-GPQGPPGPPGDDGMR 633 Score = 50.4 bits (119), Expect = 6e-06 Identities = 87/325 (26%), Positives = 110/325 (33%), Gaps = 55/325 (16%) Query: 393 LRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGG-ENVKA 449 L GPPGP G G+ PPG QG GPPG P GR G Sbjct: 439 LVEGPPGPAGPAGIMGPPGL------QGPTGPPGDPGDRGPP--------GRPGLPGADG 484 Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG----PG 505 + G + + + +G K I Q Q + GP P+G PG Sbjct: 485 LPGPPGTMLMLPFRYGGDGS---KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG 541 Query: 506 P-GGPGPAGPMGPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPS 563 P GGPG +G G +PGP QGP G GPP P G P +P Sbjct: 542 PVGGPGSSGAKGESGDPGP--QGPRGVQ----GPPGPTGKPGKRGRPGADGGRGMPGEPG 595 Query: 564 KAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWE 623 D H ++ P PGP P +GE + P G E Sbjct: 596 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGP---PGDDGMRGEDGEIGPRGLPG-----E 647 Query: 624 EYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYR 683 + + PGAP Q + + + G PG PPG Q + Sbjct: 648 AGPRGLLGPRGTPGAPGQPGMAGV-DGPPGPKGNMGPQGEPG-PPGQQGNPGPQ------ 699 Query: 684 QQAAYYGQTPGPGGPQPPPTQQGQQ 708 PGP GP PP ++G Q Sbjct: 700 -------GLPGPQGPIGPPGEKGPQ 717 Score = 43.5 bits (101), Expect = 7e-04 Identities = 27/61 (44%), Positives = 28/61 (45%), Gaps = 4/61 (6%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGGGGP 67 G P G GG G AG PPGPPG G G G GP G G +G P P G P Sbjct: 1480 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1539 Query: 68 G 68 G Sbjct: 1540 G 1540 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 11/78 (14%) Query: 3 DYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGA-------GDRGGGGPGG--GGPGGG 53 D G P P PP G G AG G GPPGA G++G G G G PG Sbjct: 1334 DKGEDGDPGQPGPP-GPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1392 Query: 54 SAGGPSQPPGGGGP-GIR 70 GP P G GP G+R Sbjct: 1393 GPVGPQGPAGKPGPEGLR 1410 Score = 39.7 bits (91), Expect = 0.010 Identities = 53/169 (31%), Positives = 65/169 (38%), Gaps = 37/169 (21%) Query: 8 GPPPGPPPPA--GGGGGAGGAGGGPPPGPPG-AGDRG----GGGPGGGGPGG-----GSA 55 GP P PP G G G G P GPPG G +G G PG GP G G + Sbjct: 682 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 741 Query: 56 G-----GPSQPPGG-GGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQK 109 G GP P G G PG R AD V+ + + G D GF G K Sbjct: 742 GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED------------GFPGFK 789 Query: 110 RQLE-DGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVG 157 + GD+ E ++ +G+ GP P R T + P G G Sbjct: 790 GDMGLKGDRGEVGQIGPRGED-----GPEGPKGRAGPTGD-PGPSGQAG 832 Score = 32.3 bits (72), Expect = 1.6 Identities = 20/44 (45%), Positives = 20/44 (45%), Gaps = 3/44 (6%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRG-GGGPGGGGPGG 52 PPGPP G G G G P G GD G G PG GP G Sbjct: 1499 PPGPPGLPGPQGPKGNKGSTGPAGQ--KGDSGLPGPPGSPGPPG 1540 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 84.3 bits (207), Expect = 3e-16 Identities = 151/563 (26%), Positives = 189/563 (33%), Gaps = 83/563 (14%) Query: 5 STGGP-------PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGS 54 + GGP P GPP PAG G G AG G P GPPG G +G G G G PG Sbjct: 909 TAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKG 968 Query: 55 AGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLE 113 GP+ G GP G+ A V ++G + + G G + Sbjct: 969 PIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1028 Query: 114 DGDQPESKKLASQGDSISSQLGPI--HPPPRTSMTEEYRVPDGMVGL--IIGRGGEQINK 169 QP A+ D GP T + P G +GL + G GE+ Sbjct: 1029 PVGQPG----AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK--- 1081 Query: 170 IQQDSGCKVQISPDSGGLPERSVSLTGA--PESVQKAKMMLDDIVSRGRGGPPGQFHDNA 227 ++G + P P GA P+ G GPPG+ + Sbjct: 1082 --GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV---------GNLGPPGEKGEPG 1130 Query: 228 NGGQNGTVQE--IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285 G G E + P G+ G KG G K DG + P+ Sbjct: 1131 ESGSPGIQGEPGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGF 1185 Query: 286 IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMI 345 GDP + D G GDR E G G P + +G+ G Sbjct: 1186 PGDPGPPGEGGPRGQD-------GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGP-- 1236 Query: 346 KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPG 405 AG + G G + +G P + + +G PGP G G Sbjct: 1237 ------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG-------PAGPAGKPGPDGLRG 1283 Query: 406 MPP--GGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQ 463 +P G +GR G GPPG P GL RG K G I Sbjct: 1284 LPGSVGQQGRPGATGQAGPPG-------PVGPPGLPGLRGDAGAKGEKGHPGLIGLIG-- 1334 Query: 464 LPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG--PGGPGPAGPMGPFNPG 521 P G+ K RG P Q E I G P+GPG PG PGPAGP G G Sbjct: 1335 --PPGEQGEKGD--RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA--KG 1388 Query: 522 PFNQGPPGAPPHAGGPPPHQYPP 544 G P GPP H PP Sbjct: 1389 ATGPGGPKGEKGVQGPPGHPGPP 1411 Score = 81.6 bits (200), Expect = 2e-15 Identities = 170/639 (26%), Positives = 213/639 (33%), Gaps = 136/639 (21%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPPGGGG--- 66 GP G G G +GG P GPPG +RG GP G G PG GP PPG G Sbjct: 764 GPRGATGKSGAKGTSGGDGPHGPPG--ERGLPGPQGPNGFPG---PKGPPGPPGKDGLPG 818 Query: 67 -PGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQL-EDGDQPESKKLA 124 PG R + +G A + G G E G + K Sbjct: 819 HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEG 878 Query: 125 SQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDS 184 ++GD GP P + P G GL GG + + SG P Sbjct: 879 TKGDP-----GPPGAPGKDGPAGLRGFP-GERGLPGTAGGPGLKGNEGPSG-----PPGP 927 Query: 185 GGLP-ERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAG 243 G P ER + +G P + G GPPG + G+ G + P G Sbjct: 928 AGSPGERGAAGSGGP---------IGPPGRPGPQGPPGAAGEKGVPGEKGPIG----PTG 974 Query: 244 KAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDIL 303 + G V G G L AG + +DG + +GDP Sbjct: 975 RDG-VQGPVG-----LPGPAGPPGVAGEDGDKGE--------VGDP-------------- 1006 Query: 304 RERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDG 363 +G G++ E+G G PV + G G + Q G K D+G Sbjct: 1007 --GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG--ARGPQGHFGA----KGDEG 1058 Query: 364 T-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRG 416 T GP + + GP + GP GPPG PG P G G Sbjct: 1059 TRGFNGPPGPIGLQGLPGPSGEKGETGDV----------GPMGPPGPPG-PRGPAGPNGA 1107 Query: 417 QGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFI 476 G GPPGG P K G GE+ Q G+P K Sbjct: 1108 DGPQGPPGGVGNLGPPGEK-----GEPGESGSPGIQ---------------GEPGVK--G 1145 Query: 477 IRGSPQQIDHAKQLIEEKIEGPLCPVG-PGP-GGPGPAGPMGPFNPGPFNQGPP------ 528 RG + + Q E GP P G GP G PGP G P +PGP +G P Sbjct: 1146 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG--FPGDPGPPGEGGPRGQDGA 1203 Query: 529 -------GAPPHAGGPPP--HQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAY 579 G P G P P PP G P P A DP A A Sbjct: 1204 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS-PGSEGRQGGKGAKGDPGAIGAPG 1262 Query: 580 YSHYYQQPPGPV--PGPAPAPAAPPAQGEPPQPPPTGQS 616 + P GP PGP P + G+ +P TGQ+ Sbjct: 1263 KTGPV-GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1300 Score = 68.6 bits (166), Expect = 2e-11 Identities = 199/748 (26%), Positives = 250/748 (33%), Gaps = 158/748 (21%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG------ 63 PPGP PAG G G G PGP GD G GP G GS G P PPG Sbjct: 314 PPGPEGPAGLIGPPGIQGN---PGP--VGDPGERGPPGRAGLPGSDGAPG-PPGTSLMLP 367 Query: 64 ---GGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120 G G G + A +A+ I + A + G+ G+ L QP S Sbjct: 368 FRFGSGGGDKGPVVAAQEAQAQAILQQ----ARLALRGPPGPMGYTGRPGPL---GQPGS 420 Query: 121 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI 180 L + S LGP P +T P G G G + + D G K Sbjct: 421 PGLKGE----SGDLGPQGPRGPQGLTG----PPGKAGRRGRAGADGARGMPGDPGVKGDR 472 Query: 181 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI 240 D GLP G P K D ++G GPPG+ + + G+ G + + Sbjct: 473 GFD--GLP-------GLPGE----KGHRGDTGAQGLPGPPGEDGERGDDGEIGP-RGLPG 518 Query: 241 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM 300 +G GL+ KG I G + DG Q P +G Sbjct: 519 ESGPRGLLGPKGPPGIP------GPPGVRGMDGPQG-----PKGSLGP------------ 555 Query: 301 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360 QG G + G+ G +P P+ + IG GE K Q G+ Sbjct: 556 -------QGEPGPPGQQGTP--GTQGLPGPQGA----IGPHGE--KGPQGKPGLPGMPGS 600 Query: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420 D GP GPP + SGP GP G PG P G +G +G Sbjct: 601 D---GPPGHPGKEGPPGTKGNQGP----------SGPQGPLGYPG-PRGVKGVDGIRGLK 646 Query: 421 GPPGGEMTFSIPTHK--CGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIR 478 G G + P K G+ RG V + G R P GDP Sbjct: 647 GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGR-TGPTGDP-------- 697 Query: 479 GSPQQIDHAKQLIEEKI------EGPLCPVG----PGPGG----------PGPAGPMGPF 518 G P + +L + +GP +G PG G GP G GP Sbjct: 698 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 757 Query: 519 NP----GPFN-QGPPGAPPHAGGPPPHQYP-------PQGWGNTYPQWQPPAPHDPSKAA 566 P GP G GA +GG PH P PQG N +P P P P Sbjct: 758 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG-PNGFP--GPKGPPGPPGKD 814 Query: 567 AAAADPNAAWAAYYSHYYQQPPGP--VPGPAPAPAAPPAQGEPPQP----PPTGQSDYTK 620 P + PPGP V GP A GE P PP Q Sbjct: 815 GLPGHPGQRGEVGFQG-KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 873 Query: 621 AWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE 680 A +E K P PGA P +D + ++ T GGPG P A Sbjct: 874 AGKEGTK---GDPGPPGA-PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 929 Query: 681 YYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708 ++ A G GGP PP + G Q Sbjct: 930 SPGERGA-----AGSGGPIGPPGRPGPQ 952 Score = 60.8 bits (146), Expect = 4e-09 Identities = 207/824 (25%), Positives = 255/824 (30%), Gaps = 242/824 (29%) Query: 8 GPP--PGPPPPAGGGGGAGGAGG-------GPP-----------PGPPGA-GDRGGGGPG 46 GPP PGPP G G G G GPP PGP GA G G GP Sbjct: 530 GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 589 Query: 47 G--GGPG-GGSAGGPSQPPGGGGPGIRKDAFADAVQ------RARQIAAKIGGDAATTVN 97 G G PG GS G P P G PG + + Q R + G Sbjct: 590 GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHK 649 Query: 98 NSTPDFGFGGQKRQL-EDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMV 156 + GF G K + GD+ E S+G+ GP P RT T + G Sbjct: 650 GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-----GPEGPKGRTGPTGD----PGPP 700 Query: 157 GLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAP-ESVQKAKMMLDDIVSRG 215 GL+ +G + + G + P+ S+ G P S +K L G Sbjct: 701 GLMGEKGKLGVPGLPGYPGRQG---------PKGSLGFPGFPGASGEKGARGLS-----G 746 Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 + GP G+ GQ G GK+G GG+ G+ G Q Sbjct: 747 KSGPRGERGPTGPRGQRGP----RGATGKSGAKGTSGGDGPHGPPGERGL------PGPQ 796 Query: 276 NTN-VDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSV 334 N P G P K + G G R E G + G P P V Sbjct: 797 GPNGFPGPKGPPGPPGK-------------DGLPGHPGQRGEVGFQ--GKTGPPGPPGVV 841 Query: 335 GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394 G G +GE TGP GPP + + Sbjct: 842 GPQ-GAAGE--------------------TGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 880 Query: 395 SGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQ 452 P GPPG PG P G RG +G G GG GL +G E Sbjct: 881 GDP-GPPGAPGKDGPAGLRGFPGERGLPGTAGGP----------GL---KGNEG------ 920 Query: 453 QTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512 P+G P GSP E G P+GP PG PGP Sbjct: 921 -------------PSGPPG-----PAGSPG---------ERGAAGSGGPIGP-PGRPGPQ 952 Query: 513 GPMG-------PFNPGPFN-------QGPPGAPPHAGGP-------------PPHQYPPQ 545 GP G P GP QGP G P AG P P Q + Sbjct: 953 GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 1012 Query: 546 GWGNTYPQWQPPAPHDP-SKAAAAAADPNAAWAAYYSHY----------YQQPPGPV--- 591 G + PP P P + AA AD H+ + PPGP+ Sbjct: 1013 GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1072 Query: 592 --PGPA--------------PAPAAP-----PAQGEPPQPPPTGQSDYTKAWEE------ 624 PGP+ P P P P + PQ PP G + E+ Sbjct: 1073 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1132 Query: 625 ------------------YYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGA 666 K QP +PG PP + V G PG Sbjct: 1133 GSPGIQGEPGVKGPRGERGEKGESGQPGEPG-PPGPKGPTGDDGPKGNPGPVGFPGDPG- 1190 Query: 667 PPGSQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQGQQ 708 PPG A+ R + GQ +PGP G PP G++ Sbjct: 1191 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234 Score = 46.2 bits (108), Expect = 1e-04 Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 3 DYSTGGPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60 D G P PG P P G G G G P G PG+ R GG G PG A G + Sbjct: 1206 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265 Query: 61 PPGGGGP 67 P G GP Sbjct: 1266 PVGPAGP 1272 Score = 45.8 bits (107), Expect = 1e-04 Identities = 80/305 (26%), Positives = 107/305 (35%), Gaps = 45/305 (14%) Query: 10 PPGPPPPAGGGGGAGGAG--GGP-PPGPPG-AGDRGGGGPGG-----GGPGGGSAGGPSQ 60 PPGP P G G G G G P PGPPG G RG G G G PG + GP+ Sbjct: 1164 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1223 Query: 61 PPGGGGPGIRKDAFADAVQRARQIAAKIGGD--AATTVNNSTPDFGFGGQKRQLEDGDQP 118 G GP ++ RQ GD A + P G + DG + Sbjct: 1224 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1283 Query: 119 ESKKLASQG----DSISSQLGPIHPPPRTSM-----TEEYRVPDGMVGLIIGRGGEQINK 169 + QG + GP+ PP + + + G++GL IG GEQ K Sbjct: 1284 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL-IGPPGEQGEK 1342 Query: 170 IQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANG 229 G + P + + + GA + G GGPPG Sbjct: 1343 -----GDRGLPGPQGSPGQKGEMGIPGASGPI-------------GPGGPPGLPGPAGPK 1384 Query: 230 GQNGTVQEIMIPAGKAGLV-----IGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLR 284 G G P G+ G+ G GE I+ L + K DGS+ D+ + Sbjct: 1385 GAKGATGP-GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1443 Query: 285 IIGDP 289 G P Sbjct: 1444 TGGAP 1448 Score = 42.7 bits (99), Expect = 0.001 Identities = 40/133 (30%), Positives = 50/133 (37%), Gaps = 22/133 (16%) Query: 495 IEGPLCPVGP----GP----GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQG 546 +EGP P GP GP G PGP G G P P G PG+ G P P Sbjct: 311 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-PGRAGLPGSDGAPGPPGTSLMLPFR 369 Query: 547 WGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAP 601 +G+ P ++A A A + PPGP+ PGP P +P Sbjct: 370 FGSGGGDKGPVVAAQEAQAQAILQQARLA--------LRGPPGPMGYTGRPGPLGQPGSP 421 Query: 602 PAQGEPPQPPPTG 614 +GE P G Sbjct: 422 GLKGESGDLGPQG 434 Score = 42.4 bits (98), Expect = 0.002 Identities = 33/85 (38%), Positives = 35/85 (41%), Gaps = 20/85 (23%) Query: 3 DYSTGGP--PPGPPPPAGGGGG------AGGAGGGPPPGPPGAGDRGG-----GGPGGGG 49 D GP PPGP PAG G GG G PPG G G G PG G Sbjct: 1086 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1145 Query: 50 PGG-----GSAGGPSQ--PPGGGGP 67 P G G +G P + PPG GP Sbjct: 1146 PRGERGEKGESGQPGEPGPPGPKGP 1170 Score = 38.9 bits (89), Expect = 0.017 Identities = 47/164 (28%), Positives = 59/164 (35%), Gaps = 45/164 (27%) Query: 393 LRSGPPGPPGGPGM--------------------PPGGRGRGRGQGNWGPPGGEMTFSIP 432 L GPPGP G G+ PPG G G GPPG + Sbjct: 310 LVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPF- 368 Query: 433 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIE 492 + G G G V A Q A ++ +R +RG P + + + Sbjct: 369 --RFGSGGGDKGPVVAAQEAQAQAILQQAR------------LALRGPPGPMGYTGR--- 411 Query: 493 EKIEGPLCPVGPGPGGPGPAGPMGPFNP-GPFNQGPPGAPPHAG 535 GPL G PG G +G +GP P GP QG G P AG Sbjct: 412 ---PGPLGQPG-SPGLKGESGDLGPQGPRGP--QGLTGPPGKAG 449 Score = 34.3 bits (77), Expect = 0.41 Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 5 STGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPP 62 ++G PG PP G G GA G PG P G++G GP G G PG P Q P Sbjct: 1365 ASGPIGPGGPPGLPGPAGPKGAKGATGPGGP-KGEKGVQGPPGHPGPPGEVIQPLPIQMP 1423 Score = 30.4 bits (67), Expect = 5.9 Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 5/34 (14%) Query: 396 GPPGPPG-----GPGMPPGGRGRGRGQGNWGPPG 424 GP GP G GPG P G +G G+ GPPG Sbjct: 1379 GPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 84.3 bits (207), Expect = 3e-16 Identities = 151/563 (26%), Positives = 189/563 (33%), Gaps = 83/563 (14%) Query: 5 STGGP-------PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGS 54 + GGP P GPP PAG G G AG G P GPPG G +G G G G PG Sbjct: 888 TAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKG 947 Query: 55 AGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLE 113 GP+ G GP G+ A V ++G + + G G + Sbjct: 948 PIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1007 Query: 114 DGDQPESKKLASQGDSISSQLGPI--HPPPRTSMTEEYRVPDGMVGL--IIGRGGEQINK 169 QP A+ D GP T + P G +GL + G GE+ Sbjct: 1008 PVGQPG----AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK--- 1060 Query: 170 IQQDSGCKVQISPDSGGLPERSVSLTGA--PESVQKAKMMLDDIVSRGRGGPPGQFHDNA 227 ++G + P P GA P+ G GPPG+ + Sbjct: 1061 --GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV---------GNLGPPGEKGEPG 1109 Query: 228 NGGQNGTVQE--IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285 G G E + P G+ G KG G K DG + P+ Sbjct: 1110 ESGSPGIQGEPGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGF 1164 Query: 286 IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMI 345 GDP + D G GDR E G G P + +G+ G Sbjct: 1165 PGDPGPPGEGGPRGQD-------GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGP-- 1215 Query: 346 KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPG 405 AG + G G + +G P + + +G PGP G G Sbjct: 1216 ------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG-------PAGPAGKPGPDGLRG 1262 Query: 406 MPP--GGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQ 463 +P G +GR G GPPG P GL RG K G I Sbjct: 1263 LPGSVGQQGRPGATGQAGPPG-------PVGPPGLPGLRGDAGAKGEKGHPGLIGLIG-- 1313 Query: 464 LPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG--PGGPGPAGPMGPFNPG 521 P G+ K RG P Q E I G P+GPG PG PGPAGP G G Sbjct: 1314 --PPGEQGEKGD--RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA--KG 1367 Query: 522 PFNQGPPGAPPHAGGPPPHQYPP 544 G P GPP H PP Sbjct: 1368 ATGPGGPKGEKGVQGPPGHPGPP 1390 Score = 81.6 bits (200), Expect = 2e-15 Identities = 170/639 (26%), Positives = 213/639 (33%), Gaps = 136/639 (21%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPPGGGG--- 66 GP G G G +GG P GPPG +RG GP G G PG GP PPG G Sbjct: 743 GPRGATGKSGAKGTSGGDGPHGPPG--ERGLPGPQGPNGFPG---PKGPPGPPGKDGLPG 797 Query: 67 -PGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQL-EDGDQPESKKLA 124 PG R + +G A + G G E G + K Sbjct: 798 HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEG 857 Query: 125 SQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDS 184 ++GD GP P + P G GL GG + + SG P Sbjct: 858 TKGDP-----GPPGAPGKDGPAGLRGFP-GERGLPGTAGGPGLKGNEGPSG-----PPGP 906 Query: 185 GGLP-ERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAG 243 G P ER + +G P + G GPPG + G+ G + P G Sbjct: 907 AGSPGERGAAGSGGP---------IGPPGRPGPQGPPGAAGEKGVPGEKGPIG----PTG 953 Query: 244 KAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDIL 303 + G V G G L AG + +DG + +GDP Sbjct: 954 RDG-VQGPVG-----LPGPAGPPGVAGEDGDKGE--------VGDP-------------- 985 Query: 304 RERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDG 363 +G G++ E+G G PV + G G + Q G K D+G Sbjct: 986 --GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG--ARGPQGHFGA----KGDEG 1037 Query: 364 T-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRG 416 T GP + + GP + GP GPPG PG P G G Sbjct: 1038 TRGFNGPPGPIGLQGLPGPSGEKGETGDV----------GPMGPPGPPG-PRGPAGPNGA 1086 Query: 417 QGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFI 476 G GPPGG P K G GE+ Q G+P K Sbjct: 1087 DGPQGPPGGVGNLGPPGEK-----GEPGESGSPGIQ---------------GEPGVK--G 1124 Query: 477 IRGSPQQIDHAKQLIEEKIEGPLCPVG-PGP-GGPGPAGPMGPFNPGPFNQGPP------ 528 RG + + Q E GP P G GP G PGP G P +PGP +G P Sbjct: 1125 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG--FPGDPGPPGEGGPRGQDGA 1182 Query: 529 -------GAPPHAGGPPP--HQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAY 579 G P G P P PP G P P A DP A A Sbjct: 1183 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS-PGSEGRQGGKGAKGDPGAIGAPG 1241 Query: 580 YSHYYQQPPGPV--PGPAPAPAAPPAQGEPPQPPPTGQS 616 + P GP PGP P + G+ +P TGQ+ Sbjct: 1242 KTGPV-GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1279 Score = 68.6 bits (166), Expect = 2e-11 Identities = 199/748 (26%), Positives = 250/748 (33%), Gaps = 158/748 (21%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG------ 63 PPGP PAG G G G PGP GD G GP G GS G P PPG Sbjct: 293 PPGPEGPAGLIGPPGIQGN---PGP--VGDPGERGPPGRAGLPGSDGAPG-PPGTSLMLP 346 Query: 64 ---GGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120 G G G + A +A+ I + A + G+ G+ L QP S Sbjct: 347 FRFGSGGGDKGPVVAAQEAQAQAILQQ----ARLALRGPPGPMGYTGRPGPL---GQPGS 399 Query: 121 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI 180 L + S LGP P +T P G G G + + D G K Sbjct: 400 PGLKGE----SGDLGPQGPRGPQGLTG----PPGKAGRRGRAGADGARGMPGDPGVKGDR 451 Query: 181 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI 240 D GLP G P K D ++G GPPG+ + + G+ G + + Sbjct: 452 GFD--GLP-------GLPGE----KGHRGDTGAQGLPGPPGEDGERGDDGEIGP-RGLPG 497 Query: 241 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM 300 +G GL+ KG I G + DG Q P +G Sbjct: 498 ESGPRGLLGPKGPPGIP------GPPGVRGMDGPQG-----PKGSLGP------------ 534 Query: 301 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360 QG G + G+ G +P P+ + IG GE K Q G+ Sbjct: 535 -------QGEPGPPGQQGTP--GTQGLPGPQGA----IGPHGE--KGPQGKPGLPGMPGS 579 Query: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420 D GP GPP + SGP GP G PG P G +G +G Sbjct: 580 D---GPPGHPGKEGPPGTKGNQGP----------SGPQGPLGYPG-PRGVKGVDGIRGLK 625 Query: 421 GPPGGEMTFSIPTHK--CGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIR 478 G G + P K G+ RG V + G R P GDP Sbjct: 626 GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGR-TGPTGDP-------- 676 Query: 479 GSPQQIDHAKQLIEEKI------EGPLCPVG----PGPGG----------PGPAGPMGPF 518 G P + +L + +GP +G PG G GP G GP Sbjct: 677 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 736 Query: 519 NP----GPFN-QGPPGAPPHAGGPPPHQYP-------PQGWGNTYPQWQPPAPHDPSKAA 566 P GP G GA +GG PH P PQG N +P P P P Sbjct: 737 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG-PNGFP--GPKGPPGPPGKD 793 Query: 567 AAAADPNAAWAAYYSHYYQQPPGP--VPGPAPAPAAPPAQGEPPQP----PPTGQSDYTK 620 P + PPGP V GP A GE P PP Q Sbjct: 794 GLPGHPGQRGEVGFQG-KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 852 Query: 621 AWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE 680 A +E K P PGA P +D + ++ T GGPG P A Sbjct: 853 AGKEGTK---GDPGPPGA-PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 908 Query: 681 YYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708 ++ A G GGP PP + G Q Sbjct: 909 SPGERGA-----AGSGGPIGPPGRPGPQ 931 Score = 60.8 bits (146), Expect = 4e-09 Identities = 207/824 (25%), Positives = 255/824 (30%), Gaps = 242/824 (29%) Query: 8 GPP--PGPPPPAGGGGGAGGAGG-------GPP-----------PGPPGA-GDRGGGGPG 46 GPP PGPP G G G G GPP PGP GA G G GP Sbjct: 509 GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 568 Query: 47 G--GGPG-GGSAGGPSQPPGGGGPGIRKDAFADAVQ------RARQIAAKIGGDAATTVN 97 G G PG GS G P P G PG + + Q R + G Sbjct: 569 GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHK 628 Query: 98 NSTPDFGFGGQKRQL-EDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMV 156 + GF G K + GD+ E S+G+ GP P RT T + G Sbjct: 629 GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-----GPEGPKGRTGPTGD----PGPP 679 Query: 157 GLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAP-ESVQKAKMMLDDIVSRG 215 GL+ +G + + G + P+ S+ G P S +K L G Sbjct: 680 GLMGEKGKLGVPGLPGYPGRQG---------PKGSLGFPGFPGASGEKGARGLS-----G 725 Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 + GP G+ GQ G GK+G GG+ G+ G Q Sbjct: 726 KSGPRGERGPTGPRGQRGP----RGATGKSGAKGTSGGDGPHGPPGERGL------PGPQ 775 Query: 276 NTN-VDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSV 334 N P G P K + G G R E G + G P P V Sbjct: 776 GPNGFPGPKGPPGPPGK-------------DGLPGHPGQRGEVGFQ--GKTGPPGPPGVV 820 Query: 335 GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394 G G +GE TGP GPP + + Sbjct: 821 GPQ-GAAGE--------------------TGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 859 Query: 395 SGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQ 452 P GPPG PG P G RG +G G GG GL +G E Sbjct: 860 GDP-GPPGAPGKDGPAGLRGFPGERGLPGTAGGP----------GL---KGNEG------ 899 Query: 453 QTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512 P+G P GSP E G P+GP PG PGP Sbjct: 900 -------------PSGPPG-----PAGSPG---------ERGAAGSGGPIGP-PGRPGPQ 931 Query: 513 GPMG-------PFNPGPFN-------QGPPGAPPHAGGP-------------PPHQYPPQ 545 GP G P GP QGP G P AG P P Q + Sbjct: 932 GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 991 Query: 546 GWGNTYPQWQPPAPHDP-SKAAAAAADPNAAWAAYYSHY----------YQQPPGPV--- 591 G + PP P P + AA AD H+ + PPGP+ Sbjct: 992 GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1051 Query: 592 --PGPA--------------PAPAAP-----PAQGEPPQPPPTGQSDYTKAWEE------ 624 PGP+ P P P P + PQ PP G + E+ Sbjct: 1052 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1111 Query: 625 ------------------YYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGA 666 K QP +PG PP + V G PG Sbjct: 1112 GSPGIQGEPGVKGPRGERGEKGESGQPGEPG-PPGPKGPTGDDGPKGNPGPVGFPGDPG- 1169 Query: 667 PPGSQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQGQQ 708 PPG A+ R + GQ +PGP G PP G++ Sbjct: 1170 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213 Score = 46.2 bits (108), Expect = 1e-04 Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 3 DYSTGGPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60 D G P PG P P G G G G P G PG+ R GG G PG A G + Sbjct: 1185 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1244 Query: 61 PPGGGGP 67 P G GP Sbjct: 1245 PVGPAGP 1251 Score = 45.8 bits (107), Expect = 1e-04 Identities = 80/305 (26%), Positives = 107/305 (35%), Gaps = 45/305 (14%) Query: 10 PPGPPPPAGGGGGAGGAG--GGP-PPGPPG-AGDRGGGGPGG-----GGPGGGSAGGPSQ 60 PPGP P G G G G G P PGPPG G RG G G G PG + GP+ Sbjct: 1143 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1202 Query: 61 PPGGGGPGIRKDAFADAVQRARQIAAKIGGD--AATTVNNSTPDFGFGGQKRQLEDGDQP 118 G GP ++ RQ GD A + P G + DG + Sbjct: 1203 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1262 Query: 119 ESKKLASQG----DSISSQLGPIHPPPRTSM-----TEEYRVPDGMVGLIIGRGGEQINK 169 + QG + GP+ PP + + + G++GL IG GEQ K Sbjct: 1263 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL-IGPPGEQGEK 1321 Query: 170 IQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANG 229 G + P + + + GA + G GGPPG Sbjct: 1322 -----GDRGLPGPQGSPGQKGEMGIPGASGPI-------------GPGGPPGLPGPAGPK 1363 Query: 230 GQNGTVQEIMIPAGKAGLV-----IGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLR 284 G G P G+ G+ G GE I+ L + K DGS+ D+ + Sbjct: 1364 GAKGATGP-GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1422 Query: 285 IIGDP 289 G P Sbjct: 1423 TGGAP 1427 Score = 42.7 bits (99), Expect = 0.001 Identities = 40/133 (30%), Positives = 50/133 (37%), Gaps = 22/133 (16%) Query: 495 IEGPLCPVGP----GP----GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQG 546 +EGP P GP GP G PGP G G P P G PG+ G P P Sbjct: 290 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-PGRAGLPGSDGAPGPPGTSLMLPFR 348 Query: 547 WGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAP 601 +G+ P ++A A A + PPGP+ PGP P +P Sbjct: 349 FGSGGGDKGPVVAAQEAQAQAILQQARLA--------LRGPPGPMGYTGRPGPLGQPGSP 400 Query: 602 PAQGEPPQPPPTG 614 +GE P G Sbjct: 401 GLKGESGDLGPQG 413 Score = 42.4 bits (98), Expect = 0.002 Identities = 33/85 (38%), Positives = 35/85 (41%), Gaps = 20/85 (23%) Query: 3 DYSTGGP--PPGPPPPAGGGGG------AGGAGGGPPPGPPGAGDRGG-----GGPGGGG 49 D GP PPGP PAG G GG G PPG G G G PG G Sbjct: 1065 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1124 Query: 50 PGG-----GSAGGPSQ--PPGGGGP 67 P G G +G P + PPG GP Sbjct: 1125 PRGERGEKGESGQPGEPGPPGPKGP 1149 Score = 38.9 bits (89), Expect = 0.017 Identities = 47/164 (28%), Positives = 59/164 (35%), Gaps = 45/164 (27%) Query: 393 LRSGPPGPPGGPGM--------------------PPGGRGRGRGQGNWGPPGGEMTFSIP 432 L GPPGP G G+ PPG G G GPPG + Sbjct: 289 LVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPF- 347 Query: 433 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIE 492 + G G G V A Q A ++ +R +RG P + + + Sbjct: 348 --RFGSGGGDKGPVVAAQEAQAQAILQQAR------------LALRGPPGPMGYTGR--- 390 Query: 493 EKIEGPLCPVGPGPGGPGPAGPMGPFNP-GPFNQGPPGAPPHAG 535 GPL G PG G +G +GP P GP QG G P AG Sbjct: 391 ---PGPLGQPG-SPGLKGESGDLGPQGPRGP--QGLTGPPGKAG 428 Score = 34.3 bits (77), Expect = 0.41 Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 5 STGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPP 62 ++G PG PP G G GA G PG P G++G GP G G PG P Q P Sbjct: 1344 ASGPIGPGGPPGLPGPAGPKGAKGATGPGGP-KGEKGVQGPPGHPGPPGEVIQPLPIQMP 1402 Score = 30.4 bits (67), Expect = 5.9 Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 5/34 (14%) Query: 396 GPPGPPG-----GPGMPPGGRGRGRGQGNWGPPG 424 GP GP G GPG P G +G G+ GPPG Sbjct: 1358 GPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 84.3 bits (207), Expect = 3e-16 Identities = 151/563 (26%), Positives = 189/563 (33%), Gaps = 83/563 (14%) Query: 5 STGGP-------PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGS 54 + GGP P GPP PAG G G AG G P GPPG G +G G G G PG Sbjct: 995 TAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKG 1054 Query: 55 AGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLE 113 GP+ G GP G+ A V ++G + + G G + Sbjct: 1055 PIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1114 Query: 114 DGDQPESKKLASQGDSISSQLGPI--HPPPRTSMTEEYRVPDGMVGL--IIGRGGEQINK 169 QP A+ D GP T + P G +GL + G GE+ Sbjct: 1115 PVGQPG----AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK--- 1167 Query: 170 IQQDSGCKVQISPDSGGLPERSVSLTGA--PESVQKAKMMLDDIVSRGRGGPPGQFHDNA 227 ++G + P P GA P+ G GPPG+ + Sbjct: 1168 --GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV---------GNLGPPGEKGEPG 1216 Query: 228 NGGQNGTVQE--IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285 G G E + P G+ G KG G K DG + P+ Sbjct: 1217 ESGSPGIQGEPGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGF 1271 Query: 286 IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMI 345 GDP + D G GDR E G G P + +G+ G Sbjct: 1272 PGDPGPPGEGGPRGQD-------GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGP-- 1322 Query: 346 KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPG 405 AG + G G + +G P + + +G PGP G G Sbjct: 1323 ------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG-------PAGPAGKPGPDGLRG 1369 Query: 406 MPP--GGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQ 463 +P G +GR G GPPG P GL RG K G I Sbjct: 1370 LPGSVGQQGRPGATGQAGPPG-------PVGPPGLPGLRGDAGAKGEKGHPGLIGLIG-- 1420 Query: 464 LPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG--PGGPGPAGPMGPFNPG 521 P G+ K RG P Q E I G P+GPG PG PGPAGP G G Sbjct: 1421 --PPGEQGEKGD--RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA--KG 1474 Query: 522 PFNQGPPGAPPHAGGPPPHQYPP 544 G P GPP H PP Sbjct: 1475 ATGPGGPKGEKGVQGPPGHPGPP 1497 Score = 81.6 bits (200), Expect = 2e-15 Identities = 170/639 (26%), Positives = 213/639 (33%), Gaps = 136/639 (21%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPPGGGG--- 66 GP G G G +GG P GPPG +RG GP G G PG GP PPG G Sbjct: 850 GPRGATGKSGAKGTSGGDGPHGPPG--ERGLPGPQGPNGFPG---PKGPPGPPGKDGLPG 904 Query: 67 -PGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQL-EDGDQPESKKLA 124 PG R + +G A + G G E G + K Sbjct: 905 HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEG 964 Query: 125 SQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDS 184 ++GD GP P + P G GL GG + + SG P Sbjct: 965 TKGDP-----GPPGAPGKDGPAGLRGFP-GERGLPGTAGGPGLKGNEGPSG-----PPGP 1013 Query: 185 GGLP-ERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAG 243 G P ER + +G P + G GPPG + G+ G + P G Sbjct: 1014 AGSPGERGAAGSGGP---------IGPPGRPGPQGPPGAAGEKGVPGEKGPIG----PTG 1060 Query: 244 KAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDIL 303 + G V G G L AG + +DG + +GDP Sbjct: 1061 RDG-VQGPVG-----LPGPAGPPGVAGEDGDKGE--------VGDP-------------- 1092 Query: 304 RERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDG 363 +G G++ E+G G PV + G G + Q G K D+G Sbjct: 1093 --GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG--ARGPQGHFGA----KGDEG 1144 Query: 364 T-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRG 416 T GP + + GP + GP GPPG PG P G G Sbjct: 1145 TRGFNGPPGPIGLQGLPGPSGEKGETGDV----------GPMGPPGPPG-PRGPAGPNGA 1193 Query: 417 QGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFI 476 G GPPGG P K G GE+ Q G+P K Sbjct: 1194 DGPQGPPGGVGNLGPPGEK-----GEPGESGSPGIQ---------------GEPGVK--G 1231 Query: 477 IRGSPQQIDHAKQLIEEKIEGPLCPVG-PGP-GGPGPAGPMGPFNPGPFNQGPP------ 528 RG + + Q E GP P G GP G PGP G P +PGP +G P Sbjct: 1232 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG--FPGDPGPPGEGGPRGQDGA 1289 Query: 529 -------GAPPHAGGPPP--HQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAY 579 G P G P P PP G P P A DP A A Sbjct: 1290 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS-PGSEGRQGGKGAKGDPGAIGAPG 1348 Query: 580 YSHYYQQPPGPV--PGPAPAPAAPPAQGEPPQPPPTGQS 616 + P GP PGP P + G+ +P TGQ+ Sbjct: 1349 KTGPV-GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1386 Score = 68.6 bits (166), Expect = 2e-11 Identities = 199/748 (26%), Positives = 250/748 (33%), Gaps = 158/748 (21%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG------ 63 PPGP PAG G G G PGP GD G GP G GS G P PPG Sbjct: 400 PPGPEGPAGLIGPPGIQGN---PGP--VGDPGERGPPGRAGLPGSDGAPG-PPGTSLMLP 453 Query: 64 ---GGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120 G G G + A +A+ I + A + G+ G+ L QP S Sbjct: 454 FRFGSGGGDKGPVVAAQEAQAQAILQQ----ARLALRGPPGPMGYTGRPGPL---GQPGS 506 Query: 121 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI 180 L + S LGP P +T P G G G + + D G K Sbjct: 507 PGLKGE----SGDLGPQGPRGPQGLTG----PPGKAGRRGRAGADGARGMPGDPGVKGDR 558 Query: 181 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI 240 D GLP G P K D ++G GPPG+ + + G+ G + + Sbjct: 559 GFD--GLP-------GLPGE----KGHRGDTGAQGLPGPPGEDGERGDDGEIGP-RGLPG 604 Query: 241 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM 300 +G GL+ KG I G + DG Q P +G Sbjct: 605 ESGPRGLLGPKGPPGIP------GPPGVRGMDGPQG-----PKGSLGP------------ 641 Query: 301 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360 QG G + G+ G +P P+ + IG GE K Q G+ Sbjct: 642 -------QGEPGPPGQQGTP--GTQGLPGPQGA----IGPHGE--KGPQGKPGLPGMPGS 686 Query: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420 D GP GPP + SGP GP G PG P G +G +G Sbjct: 687 D---GPPGHPGKEGPPGTKGNQGP----------SGPQGPLGYPG-PRGVKGVDGIRGLK 732 Query: 421 GPPGGEMTFSIPTHK--CGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIR 478 G G + P K G+ RG V + G R P GDP Sbjct: 733 GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGR-TGPTGDP-------- 783 Query: 479 GSPQQIDHAKQLIEEKI------EGPLCPVG----PGPGG----------PGPAGPMGPF 518 G P + +L + +GP +G PG G GP G GP Sbjct: 784 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 843 Query: 519 NP----GPFN-QGPPGAPPHAGGPPPHQYP-------PQGWGNTYPQWQPPAPHDPSKAA 566 P GP G GA +GG PH P PQG N +P P P P Sbjct: 844 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG-PNGFP--GPKGPPGPPGKD 900 Query: 567 AAAADPNAAWAAYYSHYYQQPPGP--VPGPAPAPAAPPAQGEPPQP----PPTGQSDYTK 620 P + PPGP V GP A GE P PP Q Sbjct: 901 GLPGHPGQRGEVGFQG-KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 959 Query: 621 AWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE 680 A +E K P PGA P +D + ++ T GGPG P A Sbjct: 960 AGKEGTK---GDPGPPGA-PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 1015 Query: 681 YYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708 ++ A G GGP PP + G Q Sbjct: 1016 SPGERGA-----AGSGGPIGPPGRPGPQ 1038 Score = 60.8 bits (146), Expect = 4e-09 Identities = 207/824 (25%), Positives = 255/824 (30%), Gaps = 242/824 (29%) Query: 8 GPP--PGPPPPAGGGGGAGGAGG-------GPP-----------PGPPGA-GDRGGGGPG 46 GPP PGPP G G G G GPP PGP GA G G GP Sbjct: 616 GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 675 Query: 47 G--GGPG-GGSAGGPSQPPGGGGPGIRKDAFADAVQ------RARQIAAKIGGDAATTVN 97 G G PG GS G P P G PG + + Q R + G Sbjct: 676 GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHK 735 Query: 98 NSTPDFGFGGQKRQL-EDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMV 156 + GF G K + GD+ E S+G+ GP P RT T + G Sbjct: 736 GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-----GPEGPKGRTGPTGD----PGPP 786 Query: 157 GLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAP-ESVQKAKMMLDDIVSRG 215 GL+ +G + + G + P+ S+ G P S +K L G Sbjct: 787 GLMGEKGKLGVPGLPGYPGRQG---------PKGSLGFPGFPGASGEKGARGLS-----G 832 Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 + GP G+ GQ G GK+G GG+ G+ G Q Sbjct: 833 KSGPRGERGPTGPRGQRGP----RGATGKSGAKGTSGGDGPHGPPGERGL------PGPQ 882 Query: 276 NTN-VDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSV 334 N P G P K + G G R E G + G P P V Sbjct: 883 GPNGFPGPKGPPGPPGK-------------DGLPGHPGQRGEVGFQ--GKTGPPGPPGVV 927 Query: 335 GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394 G G +GE TGP GPP + + Sbjct: 928 GPQ-GAAGE--------------------TGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 966 Query: 395 SGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQ 452 P GPPG PG P G RG +G G GG GL +G E Sbjct: 967 GDP-GPPGAPGKDGPAGLRGFPGERGLPGTAGGP----------GL---KGNEG------ 1006 Query: 453 QTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512 P+G P GSP E G P+GP PG PGP Sbjct: 1007 -------------PSGPPG-----PAGSPG---------ERGAAGSGGPIGP-PGRPGPQ 1038 Query: 513 GPMG-------PFNPGPFN-------QGPPGAPPHAGGP-------------PPHQYPPQ 545 GP G P GP QGP G P AG P P Q + Sbjct: 1039 GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 1098 Query: 546 GWGNTYPQWQPPAPHDP-SKAAAAAADPNAAWAAYYSHY----------YQQPPGPV--- 591 G + PP P P + AA AD H+ + PPGP+ Sbjct: 1099 GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1158 Query: 592 --PGPA--------------PAPAAP-----PAQGEPPQPPPTGQSDYTKAWEE------ 624 PGP+ P P P P + PQ PP G + E+ Sbjct: 1159 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1218 Query: 625 ------------------YYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGA 666 K QP +PG PP + V G PG Sbjct: 1219 GSPGIQGEPGVKGPRGERGEKGESGQPGEPG-PPGPKGPTGDDGPKGNPGPVGFPGDPG- 1276 Query: 667 PPGSQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQGQQ 708 PPG A+ R + GQ +PGP G PP G++ Sbjct: 1277 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320 Score = 46.2 bits (108), Expect = 1e-04 Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 3 DYSTGGPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60 D G P PG P P G G G G P G PG+ R GG G PG A G + Sbjct: 1292 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1351 Query: 61 PPGGGGP 67 P G GP Sbjct: 1352 PVGPAGP 1358 Score = 45.8 bits (107), Expect = 1e-04 Identities = 80/305 (26%), Positives = 107/305 (35%), Gaps = 45/305 (14%) Query: 10 PPGPPPPAGGGGGAGGAG--GGP-PPGPPG-AGDRGGGGPGG-----GGPGGGSAGGPSQ 60 PPGP P G G G G G P PGPPG G RG G G G PG + GP+ Sbjct: 1250 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1309 Query: 61 PPGGGGPGIRKDAFADAVQRARQIAAKIGGD--AATTVNNSTPDFGFGGQKRQLEDGDQP 118 G GP ++ RQ GD A + P G + DG + Sbjct: 1310 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1369 Query: 119 ESKKLASQG----DSISSQLGPIHPPPRTSM-----TEEYRVPDGMVGLIIGRGGEQINK 169 + QG + GP+ PP + + + G++GL IG GEQ K Sbjct: 1370 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL-IGPPGEQGEK 1428 Query: 170 IQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANG 229 G + P + + + GA + G GGPPG Sbjct: 1429 -----GDRGLPGPQGSPGQKGEMGIPGASGPI-------------GPGGPPGLPGPAGPK 1470 Query: 230 GQNGTVQEIMIPAGKAGLV-----IGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLR 284 G G P G+ G+ G GE I+ L + K DGS+ D+ + Sbjct: 1471 GAKGATGP-GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1529 Query: 285 IIGDP 289 G P Sbjct: 1530 TGGAP 1534 Score = 42.7 bits (99), Expect = 0.001 Identities = 40/133 (30%), Positives = 50/133 (37%), Gaps = 22/133 (16%) Query: 495 IEGPLCPVGP----GP----GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQG 546 +EGP P GP GP G PGP G G P P G PG+ G P P Sbjct: 397 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-PGRAGLPGSDGAPGPPGTSLMLPFR 455 Query: 547 WGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAP 601 +G+ P ++A A A + PPGP+ PGP P +P Sbjct: 456 FGSGGGDKGPVVAAQEAQAQAILQQARLA--------LRGPPGPMGYTGRPGPLGQPGSP 507 Query: 602 PAQGEPPQPPPTG 614 +GE P G Sbjct: 508 GLKGESGDLGPQG 520 Score = 42.4 bits (98), Expect = 0.002 Identities = 33/85 (38%), Positives = 35/85 (41%), Gaps = 20/85 (23%) Query: 3 DYSTGGP--PPGPPPPAGGGGG------AGGAGGGPPPGPPGAGDRGG-----GGPGGGG 49 D GP PPGP PAG G GG G PPG G G G PG G Sbjct: 1172 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1231 Query: 50 PGG-----GSAGGPSQ--PPGGGGP 67 P G G +G P + PPG GP Sbjct: 1232 PRGERGEKGESGQPGEPGPPGPKGP 1256 Score = 38.9 bits (89), Expect = 0.017 Identities = 47/164 (28%), Positives = 59/164 (35%), Gaps = 45/164 (27%) Query: 393 LRSGPPGPPGGPGM--------------------PPGGRGRGRGQGNWGPPGGEMTFSIP 432 L GPPGP G G+ PPG G G GPPG + Sbjct: 396 LVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPF- 454 Query: 433 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIE 492 + G G G V A Q A ++ +R +RG P + + + Sbjct: 455 --RFGSGGGDKGPVVAAQEAQAQAILQQAR------------LALRGPPGPMGYTGR--- 497 Query: 493 EKIEGPLCPVGPGPGGPGPAGPMGPFNP-GPFNQGPPGAPPHAG 535 GPL G PG G +G +GP P GP QG G P AG Sbjct: 498 ---PGPLGQPG-SPGLKGESGDLGPQGPRGP--QGLTGPPGKAG 535 Score = 34.3 bits (77), Expect = 0.41 Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 5 STGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPP 62 ++G PG PP G G GA G PG P G++G GP G G PG P Q P Sbjct: 1451 ASGPIGPGGPPGLPGPAGPKGAKGATGPGGP-KGEKGVQGPPGHPGPPGEVIQPLPIQMP 1509 Score = 30.4 bits (67), Expect = 5.9 Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 5/34 (14%) Query: 396 GPPGPPG-----GPGMPPGGRGRGRGQGNWGPPG 424 GP GP G GPG P G +G G+ GPPG Sbjct: 1465 GPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1498 >gi|222352151 poly(rC) binding protein 1 [Homo sapiens] Length = 356 Score = 82.0 bits (201), Expect = 2e-15 Identities = 89/350 (25%), Positives = 149/350 (42%), Gaps = 37/350 (10%) Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215 VG IIG+ GE + +I+++SG ++ IS G PER ++LTG ++ KA M+ D + Sbjct: 25 VGSIIGKKGESVKRIREESGARINIS--EGNCPERIITLTGPTNAIFKAFAMIIDKLEED 82 Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 ++ + +++PA + G +IGKGG IK+++E G ++ + D Sbjct: 83 INS---SMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139 Query: 276 NTNVDKPLRIIGDPYK----VQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPR 331 N + ++ + I G P V+Q C ++++ L + QG R+ P+P Sbjct: 140 N-STERAITIAGVPQSVTECVKQICLVMLETLSQSPQG----------RVMTIPYQPMPA 188 Query: 332 HSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIA------HIMGPPDRCEHAARI 385 S + G + + AG D GP A H + P D + Sbjct: 189 SSPVICAGGQ----DRCSDAAG--YPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVA 242 Query: 386 INDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGE 445 ++ G G G P +G E+T IP + G +IGR G Sbjct: 243 RQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELT--IPNNLIGCIIGRQGA 300 Query: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495 N+ I Q +GA ++I+ P G + I GS I A+ LI ++ Sbjct: 301 NINEIRQMSGAQIKIAN--PVEGSSG-RQVTITGSAASISLAQYLINARL 347 Score = 67.8 bits (164), Expect = 3e-11 Identities = 59/222 (26%), Positives = 90/222 (40%), Gaps = 29/222 (13%) Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393 VG +IG+ GE +K+I+ ++G RI + G PE+I + GP + A +I D L+ Sbjct: 25 VGSIIGKKGESVKRIREESGARINISE--GNCPERIITLTGPTNAIFKAFAMIIDKLEED 82 Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 + PP + +P +CG +IG+GG +K I + Sbjct: 83 INSSMTNSTAASRPPV----------------TLRLVVPATQCGSLIGKGGCKIKEIRES 126 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQ-----LIEEKIEGPLCPVGPGPGG 508 TGA V+++ + PN + I G PQ + + ++E + P V P Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQ 184 Query: 509 PGPAGPMGPFNPGPFNQGPPGAPPHA----GGPPPHQYPPQG 546 P PA G PHA GPP Y QG Sbjct: 185 PMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQG 226 Score = 53.9 bits (128), Expect = 5e-07 Identities = 26/75 (34%), Positives = 46/75 (61%) Query: 143 TSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQ 202 T T E +P+ ++G IIGR G IN+I+Q SG +++I+ G R V++TG+ S+ Sbjct: 278 TQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASIS 337 Query: 203 KAKMMLDDIVSRGRG 217 A+ +++ +S +G Sbjct: 338 LAQYLINARLSSEKG 352 Score = 52.8 bits (125), Expect = 1e-06 Identities = 51/197 (25%), Positives = 89/197 (45%), Gaps = 18/197 (9%) Query: 230 GQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGD 288 G N T+ ++ GK G +IGK GE++K+++E +G ++ + S+ ++ + + G Sbjct: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI----SEGNCPERIITLTGP 64 Query: 289 PYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKI 348 + +A M++D L E D + SR + + VP G +IG+ G IK+I Sbjct: 65 TNAIFKAFAMIIDKL-EEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEI 123 Query: 349 QNDAGVRIQFKQDD-GTGPEKIAHIMGPPDR-CEHAARIINDLLQSLRSGPPG------- 399 + G ++Q D E+ I G P E +I +L++L P G Sbjct: 124 RESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPY 183 Query: 400 ---PPGGPGMPPGGRGR 413 P P + GG+ R Sbjct: 184 QPMPASSPVICAGGQDR 200 Score = 43.1 bits (100), Expect = 9e-04 Identities = 63/287 (21%), Positives = 109/287 (37%), Gaps = 40/287 (13%) Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187 + I+S + R +T VP G +IG+GG +I +I++ +G +VQ++ D L Sbjct: 81 EDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138 Query: 188 P---ERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGK 244 P ER++++ G P+SV + + ++ P G+ T+ +PA Sbjct: 139 PNSTERAITIAGVPQSVTECVKQICLVMLETLSQSP--------QGRVMTIPYQPMPASS 190 Query: 245 AGLVIGKGGETIKQLQERAGVKMI--------LIQDGSQNTNVDKPLRIIGDPYKVQQAC 296 VI GG+ + + AG L Q + PL D K+ Q Sbjct: 191 P--VICAGGQ--DRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPL----DLAKLNQVA 242 Query: 297 EMVMDILRERDQGGFGDRNEYGSRIGG-----------GIDVPVPRHSVGVVIGRSGEMI 345 GF + + G ++ +P + +G +IGR G I Sbjct: 243 RQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANI 302 Query: 346 KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQS 392 +I+ +G +I+ + I G A +IN L S Sbjct: 303 NEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSS 349 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 80.5 bits (197), Expect = 5e-15 Identities = 180/669 (26%), Positives = 221/669 (33%), Gaps = 171/669 (25%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGP---------PGA----------GDRGGGGPGG---- 47 PG P PAG G G G PPGP PGA G RG GP G Sbjct: 313 PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGE 372 Query: 48 -GGPGGGSAGGPSQPPGGGG-PGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGF 105 G PG A GP+ PG G PG A A IA G A + G Sbjct: 373 PGPPGPAGAAGPAGNPGADGQPG------AKGANGAPGIAGAPGFPGARGPSGPQGPGGP 426 Query: 106 GGQKRQLEDGDQPESKKLASQGDS-ISSQLGP--IHPPPRTSMTEEYR------VPDGMV 156 G K G+ E S+GD+ + GP + PP + E R P G+ Sbjct: 427 PGPK-----GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLP 481 Query: 157 GLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGR 216 G RGG P S G P + V K + S G Sbjct: 482 GPPGERGG-----------------PGSRGFP--------GADGVAGPKGPAGERGSPGP 516 Query: 217 GGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN 276 GP G + G+ G E +P K GL G + G QDG Sbjct: 517 AGPKG------SPGEAGRPGEAGLPGAK-GLT---GSPGSPGPDGKTGPPGPAGQDGRPG 566 Query: 277 TNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGV 336 G P QA M +G G+ + G R VP P +VG Sbjct: 567 PP--------GPPGARGQAGVMGF----PGPKGAAGEPGKAGER-----GVPGPPGAVGP 609 Query: 337 VIGRSGEMIKK----IQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAAR--IINDLL 390 G+ GE + AG R + G + + GPP + DL Sbjct: 610 A-GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDL- 667 Query: 391 QSLRSGPPGPPG--------------GPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKC 436 G PGP G GP P G RG GN G G P Sbjct: 668 -----GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPG--- 719 Query: 437 GLVIGRGGENVKAINQQTGAFVEISRQLP-PNGDPNFKLFIIRGSPQQIDHAKQLIEEK- 494 +G ++ + + GA LP P GD P+ D + + Sbjct: 720 ----SQGAPGLQGMPGERGA-----AGLPGPKGDRG------DAGPKGADGSPGKDGVRG 764 Query: 495 IEGPLCPVGP--GPGGPGPAGPMGPFNP-----GPFNQGPPGAPPHAGGPPPHQYPPQGW 547 + GP+ P GP PG G +GP GP P P ++G PG P GP PP Sbjct: 765 LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP----GPAGFAGPPGAD 820 Query: 548 GNTYPQWQPPAPHDPSKAAAA--AADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQG 605 G QP A +P A A A P A A PPGP+ G AP A A+G Sbjct: 821 G------QPGAKGEPGDAGAKGDAGPPGPAGPA-------GPPGPI-GNVGAPGAKGARG 866 Query: 606 EPPQPPPTG 614 P TG Sbjct: 867 SAGPPGATG 875 Score = 73.2 bits (178), Expect = 8e-13 Identities = 195/753 (25%), Positives = 223/753 (29%), Gaps = 140/753 (18%) Query: 10 PPGPPPPAGGGGGA---GGAGGGPPPGPPGA-------------------------GDRG 41 PPGPP G G A G G PPGP GA GD G Sbjct: 222 PPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAG 281 Query: 42 GGGPGG--GGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNS 99 GP G G PG A G P G G R A A R A G T Sbjct: 282 PAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAG 341 Query: 100 TPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLI 159 P F G + E G Q QG + + GP P DG G Sbjct: 342 PPGFP-GAVGAKGEAGPQGPRGSEGPQG--VRGEPGPPGPAGAAGPAGNPGA-DGQPGAK 397 Query: 160 IGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGR--- 216 G I G + P G P +G P A D ++G Sbjct: 398 GANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEP----GAPGSKGDTGAKGEPGP 453 Query: 217 ---GGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDG 273 GPPG + G G +P G G G G AG K + G Sbjct: 454 VGVQGPPGPAGEEGKRGARGEPGPTGLP-GPPGERGGPGSRGFPGADGVAGPKGPAGERG 512 Query: 274 SQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHS 333 S P G P + R + G G + GS G D Sbjct: 513 SPG-----PAGPKGSPGEAG----------RPGEAGLPGAKGLTGSPGSPGPDGKTGPPG 557 Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393 GR G G R Q GP+ A G P + Sbjct: 558 PAGQDGRPGP-----PGPPGARGQAGVMGFPGPKGAA---GEPGKAG------------- 596 Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGP--PGGEMTFSIPTHKCGL-----VIGRGGEN 446 G PGPPG G P G G QG GP P GE P G G GE Sbjct: 597 ERGVPGPPGAVG-PAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655 Query: 447 VKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP-- 504 K Q + G+ RG P E ++GP P GP Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGE--------RGFPG---------ERGVQGPPGPAGPRG 698 Query: 505 ---GPGGPGPAGPMG-PFNPG----PFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQP 556 PG G G G P PG P QG PG AG P P G+ P+ Sbjct: 699 ANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPG----PKGDRGDAGPKGAD 754 Query: 557 PAP-HDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQ 615 +P D + P A P GP GP A AP +GEP P P G Sbjct: 755 GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA-GPTGARGAPGDRGEPGPPGPAGF 813 Query: 616 SDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYS 675 + A QPGA + A K A GP PPG + Sbjct: 814 AGPPGA-----------DGQPGAKGEPGDAGA-----KGDAGPPGPAGPAGPPGPIGNVG 857 Query: 676 AAWAEYYRQQAAYYGQT--PGPGGPQPPPTQQG 706 A A+ R A G T PG G PP G Sbjct: 858 APGAKGARGSAGPPGATGFPGAAGRVGPPGPSG 890 Score = 67.8 bits (164), Expect = 3e-11 Identities = 184/738 (24%), Positives = 223/738 (30%), Gaps = 167/738 (22%) Query: 6 TGGP-PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQ 60 TG P PGP G G AG G PPGPPGA + G G PG G G G AG Sbjct: 541 TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGV 600 Query: 61 PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120 P G PG A D A+ G GF G G E+ Sbjct: 601 P---GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA--GPPGEA 655 Query: 121 KKLASQGDSISSQLGPIHPPPRTSMTEE-------YRVPDGMVGLIIGRGGEQINKIQQD 173 K QG + LG P P + E + P G G G + + D Sbjct: 656 GKPGEQG--VPGDLGA--PGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGD 711 Query: 174 SGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNG 233 +G +P S G P L G P RG G PG D + G Sbjct: 712 AGAPG--APGSQGAP----GLQGMPGE-------------RGAAGLPGPKGDRGDAG--- 749 Query: 234 TVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQ 293 P G G G + ++ L G G DK P Sbjct: 750 -------PKGADG---SPGKDGVRGLTGPIG------PPGPAGAPGDKGESGPSGPAGPT 793 Query: 294 QACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAG 353 A +G GDR E G G P G G DAG Sbjct: 794 GA------------RGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG--------DAG 833 Query: 354 VRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGM--PPGGR 411 + GP A GPP + G PG G G PPG Sbjct: 834 AK------GDAGPPGPAGPAGPPGPIGNV-------------GAPGAKGARGSAGPPGAT 874 Query: 412 GRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPN 471 G G GPPG P G GG+ + G E+ PP Sbjct: 875 GFPGAAGRVGPPGPSGNAG-PPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGE 933 Query: 472 FKLFIIRGSPQQIDHAKQLIEEKIEGPL-CPVGPGPGG----------PGPAGPMG-PFN 519 +GSP +GP P PGP G PG G G P Sbjct: 934 ------KGSPGA------------DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL 975 Query: 520 PGPFN----QGPPGA-----PPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAA 570 PGP QGP GA PP GPP PP G + + P A P + + A Sbjct: 976 PGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPP---GESGREGAPGAEGSPGRDGSPGA 1032 Query: 571 DPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIG 630 + P GP PG AP AP G + G++ Sbjct: 1033 KGDRGETG--------PAGP-PGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGA 1083 Query: 631 QQPQQPGAP--PQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAY 688 + P P P + + + + K + GP PPGS + + A Sbjct: 1084 RGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGAS-------- 1135 Query: 689 YGQTPGPGGPQPPPTQQG 706 GP GP+ PP G Sbjct: 1136 -----GPAGPRGPPGSAG 1148 Score = 67.4 bits (163), Expect = 4e-11 Identities = 198/778 (25%), Positives = 260/778 (33%), Gaps = 142/778 (18%) Query: 8 GPPPGPP-----PPAGGGGGAGGAGGGPPP----GPPGAGDRGGGGPGGGGPGGGSAGGP 58 G PPGP P A G G GA G P P GPPG G G P G G P Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP--GPTGLP 481 Query: 59 SQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQP 118 P GGPG R AD V + A + G S + G G + P Sbjct: 482 GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPG------EAGLP 535 Query: 119 ESKKLASQGDSISSQLGPIHP--PPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGC 176 +K L S GP PP + + P G G RG + G Sbjct: 536 GAKGLTGSPGS----PGPDGKTGPPGPAGQDGRPGPPGPPG---ARGQAGVMGFPGPKGA 588 Query: 177 KVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGT-- 234 + + G ER V G P +V A + ++G GP G + G G+ Sbjct: 589 ----AGEPGKAGERGV--PGPPGAVGPAGKD-GEAGAQGPPGPAGPAGERGEQGPAGSPG 641 Query: 235 VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQ 294 Q + PAG G GK GE + + G G + ++ ++ P + Sbjct: 642 FQGLPGPAGPPG-EAGKPGE--QGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRG 698 Query: 295 ACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGV 354 A + + D G G G+ G +P R + G+ G G+ + DAG Sbjct: 699 ANGAPGNDGAKGDAGAPGAPGSQGA--PGLQGMPGERGAAGLP-GPKGD-----RGDAGP 750 Query: 355 RIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGP---------------PG 399 + G + +GPP A D +S SGP PG Sbjct: 751 KGADGSPGKDGVRGLTGPIGPPG----PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPG 806 Query: 400 PPGGPGM--PPGGRGR---------GRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGEN 446 PPG G PPG G+ +G+ GPPG G P G +G Sbjct: 807 PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARG 866 Query: 447 VKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGP 506 TG R PP N G P A +E +GP GP Sbjct: 867 SAGPPGATGFPGAAGRVGPPGPSGN------AGPPGPPGPAG---KEGGKGPRGETGPA- 916 Query: 507 GGPGPAGPMGPFNPGPFNQ-GPPGAPPHAGGP--PPHQ----------YPPQGWGNTYPQ 553 G PG GP GP PGP + G PGA AG P P Q P Q +P Sbjct: 917 GRPGEVGPPGP--PGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974 Query: 554 WQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV--------PGPAPAPAAPPAQG 605 P+ +P K + A + PPGP+ PG + AP A+G Sbjct: 975 LPGPS-GEPGKQGPSGASGE-----------RGPPGPMGPPGLAGPPGESGREGAPGAEG 1022 Query: 606 EPPQP-PPTGQSDYTKAWEEYYKKIGQQPQQPGAP----PQQDYTKAWEEYYKKQAQVA- 659 P + P + D + P PGAP P K+ + A A Sbjct: 1023 SPGRDGSPGAKGDRGETGP------AGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAG 1076 Query: 660 -----TGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQT--PGPGGPQPPPTQQGQQQA 710 GP P G + D + R + G + GP GP P +QG A Sbjct: 1077 PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGA 1134 Score = 65.5 bits (158), Expect = 2e-10 Identities = 101/327 (30%), Positives = 116/327 (35%), Gaps = 56/327 (17%) Query: 396 GPPGPPGGPGMPPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 GP GP G PG PPG G QG GPPG GE S P G G G+N + + Sbjct: 182 GPSGPRGLPG-PPGAPGP---QGFQGPPGEPGEPGASGPMGPRG-PPGPPGKN--GDDGE 234 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP--GPGGPGP 511 G + PP L G P H + +G P GP PG PG Sbjct: 235 AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGE 294 Query: 512 AGPMGPFNPG--PFNQGPPGAPPHAG-----GPPPHQYPPQGWGNTYPQWQPPAPHDPSK 564 G G P P +G PGAP AG G PP G T P P P + Sbjct: 295 NGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP---GPTGPAGPPGFP--GAV 349 Query: 565 AAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPA--PAA-PPAQGEPPQPPPTGQSDYTKA 621 A A P + + PGP PGPA A PA P A G+P G A Sbjct: 350 GAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA 408 Query: 622 WEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEY 681 + PQ PG PP G PGA PGS+ D A Sbjct: 409 PGFPGARGPSGPQGPGGPP---------------GPKGNSGEPGA-PGSKGDTGAK---- 448 Query: 682 YRQQAAYYGQTPGPGGPQPPPTQQGQQ 708 PGP G Q PP G++ Sbjct: 449 ---------GEPGPVGVQGPPGPAGEE 466 Score = 64.7 bits (156), Expect = 3e-10 Identities = 72/242 (29%), Positives = 81/242 (33%), Gaps = 64/242 (26%) Query: 396 GPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 GPPGP G PG+ PPG GR G G PG + G K + Sbjct: 995 GPPGPMGPPGLAGPPGESGREGAPGAEGSPGRD----------------GSPGAKGDRGE 1038 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP-GP-GGPGP 511 TG P G P G+P + A + + GP P GP GP G GP Sbjct: 1039 TGP-------AGPPGAPGAP-----GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGP 1086 Query: 512 AGPMGPFNPG--PFNQGPPGAPPHAG-----GPPPHQYPPQGWGNTYPQWQ--PPAPHDP 562 AGP GP QG G H G GPP PP G P P P P Sbjct: 1087 AGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPG---PPGSPGEQGPSGASGPAGPRGP 1143 Query: 563 SKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAP----------APAAPPAQGEPPQPPP 612 +A A PGP+ P P P PP PP PP Sbjct: 1144 PGSAGAPGKDGLNGL----------PGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPS 1193 Query: 613 TG 614 G Sbjct: 1194 AG 1195 Score = 53.9 bits (128), Expect = 5e-07 Identities = 97/359 (27%), Positives = 115/359 (32%), Gaps = 69/359 (19%) Query: 396 GPPGP-----------PGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGG 444 GPPGP P GP P G RG +G GPPG P G G Sbjct: 770 GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPG-------PAGFAGPPGADGQ 822 Query: 445 ENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP 504 K GA + P G P I + + G P G Sbjct: 823 PGAKGEPGDAGAKGDAGPPGPAGP---------AGPPGPIGNVGAPGAKGARGSAGPPG- 872 Query: 505 GPGGPGPAGPMGPFNPGPF-NQGPPGAPPHAG-----GPPPHQYPPQGWGNTYPQWQP-P 557 G PG AG +GP PGP N GPPG P AG GP P G P P P Sbjct: 873 ATGFPGAAGRVGP--PGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP 930 Query: 558 APHDPSKAA----AAAADPNAAWAAYYSHYYQQP--------PGPVPGPAPAPAAPP--- 602 A S A A P A P PG +PGP+ P Sbjct: 931 AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG-LPGPSGEPGKQGPSG 989 Query: 603 AQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG 662 A GE P P G E ++ P G+P + A + + + G Sbjct: 990 ASGERGPPGPMGPPGLAGPPGESGRE--GAPGAEGSPGRDGSPGAKGD----RGETGPAG 1043 Query: 663 GPGAP--PGSQPDYSAAWAEYYRQQAAYYGQTP--------GPGGPQPPPTQQGQQQAQ 711 PGAP PG+ A R + G GP GPQ P +G+ Q Sbjct: 1044 PPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQ 1102 Score = 53.9 bits (128), Expect = 5e-07 Identities = 67/226 (29%), Positives = 73/226 (32%), Gaps = 68/226 (30%) Query: 395 SGPPGPPGGPGM-----PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKA 449 +GP GPPG PG P G G+ +G GP G P G V RG + Sbjct: 1039 TGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAG-------PAGPVGPVGARGPAGPQG 1091 Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGP 509 G E GD K RG G P GP PG P Sbjct: 1092 PRGDKGETGE-------QGDRGIKGH--RG---------------FSGLQGPPGP-PGSP 1126 Query: 510 GPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAA 569 G GP G P GP G P AG P G PP P + A Sbjct: 1127 GEQGPSGASGPA----GPRGPPGSAGAP-----GKDGLNGLPGPIGPPGPRGRTGDAGPV 1177 Query: 570 ADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEP----PQPP 611 PPGP PGP P P PP+ G PQPP Sbjct: 1178 G----------------PPGP-PGP-PGPPGPPSAGFDFSFLPQPP 1205 Score = 52.0 bits (123), Expect = 2e-06 Identities = 145/581 (24%), Positives = 183/581 (31%), Gaps = 91/581 (15%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPSQP-----PG-G 64 G P P+G G G G GPPG AG RG G G G AG P P PG Sbjct: 668 GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQ 727 Query: 65 GGPGIRKDAFADAVQRARQIAAKIGGDAATT---VNNSTPDFGFGGQKRQLEDGDQPESK 121 G PG R A + R A G D + V T G G GD+ ES Sbjct: 728 GMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGA--PGDKGESG 785 Query: 122 KLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQIS 181 G + + P + P G G +G + D+G Sbjct: 786 PSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAG 845 Query: 182 PDSGGLPERSVSLTGAPESVQKAKM--MLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIM 239 P P +V GA + A + GR GPPG + N G G Sbjct: 846 PAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGP---SGNAGPPG------ 896 Query: 240 IPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ----NTNVDKPLRIIGDPYKVQQA 295 P G AG GKG R G G + D P G P A Sbjct: 897 -PPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIA 955 Query: 296 CEM-VMDILRERDQGGF-------GDRNEYG-SRIGGGIDVPVPRHSVGVVIGRSGEMIK 346 + V+ + +R + GF G+ + G S G P P G+ G GE Sbjct: 956 GQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA-GPPGE--- 1011 Query: 347 KIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGM 406 +G E G P R + + D ++ +GPPG PG PG Sbjct: 1012 -----------------SGREGAPGAEGSPGR-DGSPGAKGDRGETGPAGPPGAPGAPGA 1053 Query: 407 P----PGGRGRGRGQ-------------------------GNWGPPGGEMTFSIPTHK-- 435 P P G+ RG+ G+ G G + I H+ Sbjct: 1054 PGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGF 1113 Query: 436 CGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495 GL G +GA + PP + G P I Sbjct: 1114 SGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD 1173 Query: 496 EGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGG 536 GP+ P GP PG PGP GP F PP H GG Sbjct: 1174 AGPVGPPGP-PGPPGPPGPPSAGFDFSFLPQPPQEKAHDGG 1213 Score = 50.1 bits (118), Expect = 7e-06 Identities = 97/366 (26%), Positives = 112/366 (30%), Gaps = 71/366 (19%) Query: 396 GPPGPPGGPGM--------------PPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKC 436 GPPG GGPG P G RG G G PG GE +P K Sbjct: 482 GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEA--GLPGAK- 538 Query: 437 GLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFK----LFIIRGSPQQIDHAKQLIE 492 GL G G + R PP G P + + G + E Sbjct: 539 GLTGSPGSPGPDGKTGPPGPAGQDGRPGPP-GPPGARGQAGVMGFPGPKGAAGEPGKAGE 597 Query: 493 EKIEGPLCPVGP--------GPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPP 544 + GP VGP G PGPAGP G QGP G+P G P P PP Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG----EQGPAGSPGFQGLPGP-AGPP 652 Query: 545 QGWGNTYPQWQP---PAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGP----------- 590 G Q P AP PS A P Q PPGP Sbjct: 653 GEAGKPGEQGVPGDLGAP-GPSGARGERGFPG-------ERGVQGPPGPAGPRGANGAPG 704 Query: 591 ---VPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKA 647 G A AP AP +QG P G+ + P+ P +D + Sbjct: 705 NDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG 764 Query: 648 WEEYYKKQAQVATGG--GPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQ 705 G G P G A A R + PGP G PP Sbjct: 765 LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPG----PPGPAGFAGPPGAD 820 Query: 706 GQQQAQ 711 GQ A+ Sbjct: 821 GQPGAK 826 Score = 49.3 bits (116), Expect = 1e-05 Identities = 31/70 (44%), Positives = 34/70 (48%), Gaps = 12/70 (17%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG-----GGPGGGGPGG-----GSAG--G 57 PPGPP G G +G +G P GPPG+ G G PG GP G G AG G Sbjct: 1119 PPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVG 1178 Query: 58 PSQPPGGGGP 67 P PPG GP Sbjct: 1179 PPGPPGPPGP 1188 Score = 47.8 bits (112), Expect = 4e-05 Identities = 27/66 (40%), Positives = 27/66 (40%), Gaps = 2/66 (3%) Query: 3 DYSTGGP--PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60 D GP P GPP P G G G G GPPGA G G PG GP Sbjct: 837 DAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPG 896 Query: 61 PPGGGG 66 PPG G Sbjct: 897 PPGPAG 902 Score = 47.0 bits (110), Expect = 6e-05 Identities = 36/78 (46%), Positives = 38/78 (48%), Gaps = 14/78 (17%) Query: 5 STGG-PPPGPPPPAGGGG-----GAGGAGG--GPP--PGPPGA----GDRGGGGPGGGGP 50 STGG PGP P+G G GA G G GPP PG PGA G RG GP G Sbjct: 171 STGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNG 230 Query: 51 GGGSAGGPSQPPGGGGPG 68 G AG P +P G PG Sbjct: 231 DDGEAGKPGRPGERGPPG 248 Score = 46.6 bits (109), Expect = 8e-05 Identities = 86/340 (25%), Positives = 105/340 (30%), Gaps = 98/340 (28%) Query: 395 SGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQT 454 +GPPGP G P PPG G +G GP G RG E + + + Sbjct: 331 AGPPGPTG-PAGPPGFPGAVGAKGEAGPQGP----------------RGSEGPQGVRGEP 373 Query: 455 GAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGP 514 G + P G+P G P K + PG PG GP Sbjct: 374 GP-PGPAGAAGPAGNPGAD-----GQPGA----------KGANGAPGIAGAPGFPGARGP 417 Query: 515 MGPFNPG-----PFNQGPPGAPPHAG--------GPPPHQYPP---QGWGNTYPQWQP-- 556 GP PG N G PGAP G GP Q PP G + +P Sbjct: 418 SGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGP 477 Query: 557 ---PAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAPPAQGEPP 608 P P + P A A P GP PGPA +P G P Sbjct: 478 TGLPGPPGERGGPGSRGFPGADGVA-------GPKGPAGERGSPGPAGPKGSPGEAGRPG 530 Query: 609 QPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPP 668 + G T + PG+P T A GP PP Sbjct: 531 EAGLPGAKGLTGS--------------PGSPGPDGKTGP-----PGPAGQDGRPGPPGPP 571 Query: 669 GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708 G+ R QA G PGP G P + G++ Sbjct: 572 GA------------RGQAGVMG-FPGPKGAAGEPGKAGER 598 Score = 45.8 bits (107), Expect = 1e-04 Identities = 31/68 (45%), Positives = 32/68 (47%), Gaps = 7/68 (10%) Query: 7 GGPPP----GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPSQP 61 G P P GPP PAG G G G P G PG G+RGG G G PG GP P Sbjct: 449 GEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPG-SRGFPGADGVAGPKGP 507 Query: 62 PG-GGGPG 68 G G PG Sbjct: 508 AGERGSPG 515 Score = 43.5 bits (101), Expect = 7e-04 Identities = 46/134 (34%), Positives = 50/134 (37%), Gaps = 22/134 (16%) Query: 495 IEGPLCPVGPGPGGPGPAGPMG----PFNPG-PFNQGPPG--APPHAGGPPPHQ----YP 543 +EGP GP G GPAGP G P PG P GPPG PP GG Q Y Sbjct: 110 VEGPKGDTGPR-GPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYD 168 Query: 544 PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPA 603 + G P P PS P A +Q PPG PG P + P Sbjct: 169 EKSTGGI----SVPGPMGPSGPRGLPGPPGAPG----PQGFQGPPGE-PG-EPGASGPMG 218 Query: 604 QGEPPQPPPTGQSD 617 PP PP D Sbjct: 219 PRGPPGPPGKNGDD 232 Score = 43.5 bits (101), Expect = 7e-04 Identities = 31/82 (37%), Positives = 33/82 (40%), Gaps = 25/82 (30%) Query: 10 PPGPPPPAGGGGG----------------------AGGAGGGPPPGPPGA-GDRGGGGPG 46 PPGPP P G GG G +G PGPPGA G +G GP Sbjct: 146 PPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPP 205 Query: 47 G--GGPGGGSAGGPSQPPGGGG 66 G G PG GP PPG G Sbjct: 206 GEPGEPGASGPMGPRGPPGPPG 227 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/67 (38%), Positives = 28/67 (41%), Gaps = 6/67 (8%) Query: 8 GPPPGPPP-----PAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPP 62 GPP P P P G G G +G P GPPG + G G PG GP P Sbjct: 191 GPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQ 250 Query: 63 GGGG-PG 68 G G PG Sbjct: 251 GARGLPG 257 Score = 42.0 bits (97), Expect = 0.002 Identities = 24/56 (42%), Positives = 24/56 (42%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGG 65 P GPP AG G G G P GPPG R G G PG GP PP G Sbjct: 1140 PRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195 Score = 41.6 bits (96), Expect = 0.003 Identities = 34/99 (34%), Positives = 40/99 (40%), Gaps = 11/99 (11%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGG----PGGGGPGGGSAGGPSQPPGG 64 PPG P G G G G PPGPPG GD G G PG GP G G P Sbjct: 204 PPGEPGEPGASGPMGPRG---PPGPPGKNGDDGEAGKPGRPGERGP-PGPQGARGLPGTA 259 Query: 65 GGPGIRKDAFADAVQRARQIAAKIG--GDAATTVNNSTP 101 G PG++ + A+ A G G+ + N P Sbjct: 260 GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP 298 Score = 39.7 bits (91), Expect = 0.010 Identities = 30/76 (39%), Positives = 32/76 (42%), Gaps = 19/76 (25%) Query: 11 PGPPPPAG--GGGGAGG--------------AGGGPPPGPPG-AGDRGGGGPGGGGPGGG 53 PGPP P G G G GG GG PGP G +G RG GP G G Sbjct: 141 PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQG 200 Query: 54 SAGGPSQP--PGGGGP 67 G P +P PG GP Sbjct: 201 FQGPPGEPGEPGASGP 216 Score = 39.7 bits (91), Expect = 0.010 Identities = 27/75 (36%), Positives = 29/75 (38%), Gaps = 16/75 (21%) Query: 10 PPGPPPPAGGGGGAGGAGGGP------------PPGPPGA----GDRGGGGPGGGGPGGG 53 P GP P G G G G PPGPPG+ G G GP G G Sbjct: 1086 PAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPG 1145 Query: 54 SAGGPSQPPGGGGPG 68 SAG P + G PG Sbjct: 1146 SAGAPGKDGLNGLPG 1160 Score = 35.4 bits (80), Expect = 0.18 Identities = 25/62 (40%), Positives = 25/62 (40%), Gaps = 4/62 (6%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGGGSAGGPSQPPGG 64 G P G G G G P GP G R G G PG GP G GP PPG Sbjct: 98 GSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPP--GPPGPPGL 155 Query: 65 GG 66 GG Sbjct: 156 GG 157 Score = 34.7 bits (78), Expect = 0.31 Identities = 29/73 (39%), Positives = 29/73 (39%), Gaps = 14/73 (19%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGG------------GPGGGSAG 56 P GP PAG G G G PGPPG G G G GG GG S Sbjct: 119 PRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVP 178 Query: 57 GPSQPPGGGG-PG 68 GP P G G PG Sbjct: 179 GPMGPSGPRGLPG 191 Score = 32.3 bits (72), Expect = 1.6 Identities = 25/64 (39%), Positives = 26/64 (40%), Gaps = 6/64 (9%) Query: 10 PPGPPPPAGGGGGAGGAGGGP-PPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPG 68 P GPP P G G AG G P PPGPPG G P G P + GG Sbjct: 1161 PIGPPGPRGRTGDAGPV-GPPGPPGPPGP----PGPPSAGFDFSFLPQPPQEKAHDGGRY 1215 Query: 69 IRKD 72 R D Sbjct: 1216 YRAD 1219 >gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] Length = 365 Score = 80.5 bits (197), Expect = 5e-15 Identities = 85/354 (24%), Positives = 145/354 (40%), Gaps = 37/354 (10%) Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215 VG IIG+ GE + K++++SG ++ IS G PER ++L G ++ KA M+ D + Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 ++ + +++PA + G +IGKGG IK+++E G ++ + D Sbjct: 83 ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139 Query: 276 NTNVDKPLRIIGDPYK----VQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-P 330 N + ++ + I G P V+Q C ++++ L + G+ +P P Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLETLSQSPP--------------KGVTIPYRP 184 Query: 331 RHSVGVVIGRSGEMIKKIQNDAG-----VRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385 + S VI G+ +D+ D GP A+ + Sbjct: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 244 Query: 386 INDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFS----IPTHKCGLVIG 441 L +S P G G +G WG T S IP G +IG Sbjct: 245 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIG 304 Query: 442 RGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495 R G + I Q +GA ++I+ + + D + I GS I A+ LI ++ Sbjct: 305 RQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 355 Score = 68.2 bits (165), Expect = 3e-11 Identities = 62/230 (26%), Positives = 93/230 (40%), Gaps = 37/230 (16%) Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393 VG +IG+ GE +KK++ ++G RI + G PE+I + GP + A +I D L+ Sbjct: 25 VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 S PP + +P +CG +IG+GG +K I + Sbjct: 83 ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIE--------GPLCPVGP 504 TGA V+++ + PN + I G PQ I+ KQ+ +E G P P Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRP 184 Query: 505 GPGGPGP--AGPMGPFNPGPFNQGPPGAP------PHAGGPPPHQYPPQG 546 P AG ++ G + P P GPP Y QG Sbjct: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQG 234 Score = 55.1 bits (131), Expect = 2e-07 Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 17/197 (8%) Query: 229 GGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIG 287 GG N T+ ++ GK G +IGK GE++K+++E +G ++ + S+ ++ + + G Sbjct: 8 GGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAG 63 Query: 288 DPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKK 347 + +A M++D L E D + SR + + VP G +IG+ G IK+ Sbjct: 64 PTNAIFKAFAMIIDKL-EEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKE 122 Query: 348 IQNDAGVRIQFKQDD-GTGPEKIAHIMG-PPDRCEHAARIINDLLQSLRSGP-------- 397 I+ G ++Q D E+ I G P E +I +L++L P Sbjct: 123 IRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPY 182 Query: 398 -PGPPGGPGMPPGGRGR 413 P P P + GG+ R Sbjct: 183 RPKPSSSPVIFAGGQDR 199 Score = 53.1 bits (126), Expect = 9e-07 Identities = 25/73 (34%), Positives = 47/73 (64%) Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205 + E +P+ ++G IIGR G +IN+I+Q SG +++I+ G +R V++TG+ S+ A+ Sbjct: 289 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 348 Query: 206 MMLDDIVSRGRGG 218 +++ +S GG Sbjct: 349 YLINVRLSSETGG 361 Score = 43.1 bits (100), Expect = 9e-04 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%) Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187 + ISS + R +T VP G +IG+GG +I +I++ +G +VQ++ D L Sbjct: 81 EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138 Query: 188 P---ERSVSLTGAPESV 201 P ER++++ G P+S+ Sbjct: 139 PNSTERAITIAGIPQSI 155 Score = 30.0 bits (66), Expect = 7.7 Identities = 18/71 (25%), Positives = 31/71 (43%) Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385 ++ +P +G +IGR G I +I+ +G +I+ ++ I G A + Sbjct: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 350 Query: 386 INDLLQSLRSG 396 IN L S G Sbjct: 351 INVRLSSETGG 361 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 80.5 bits (197), Expect = 5e-15 Identities = 72/226 (31%), Positives = 84/226 (37%), Gaps = 35/226 (15%) Query: 501 PVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPH 560 P+GPGPG GP P+ P P Q PP P PPPHQ PP + Q PP P Sbjct: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQ-PPPPPQ 104 Query: 561 DPSKAAAA----------AADPNAAWAAYYSHYYQ-QPPGPVPGPAPAPAAPPAQGEPPQ 609 D SK A +A P ++ A + PPG PGP P P P Sbjct: 105 DSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGA 164 Query: 610 PPPTGQSDYTKAWEEYYKKIGQQPQQ------PGAPPQQDYTKAWEEYYKKQAQVATGGG 663 PPPT S + G P PG P+Q + K GGG Sbjct: 165 PPPTPPSSGVPTTP---PQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGG 221 Query: 664 PG--------APP---GSQPDYSAAWAEYYRQQAAYYGQTPGPGGP 698 PG PP G +P Y QQ + Q P PGGP Sbjct: 222 PGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQ---HHQGPPPGGP 264 Score = 56.2 bits (134), Expect = 1e-07 Identities = 32/69 (46%), Positives = 35/69 (50%), Gaps = 7/69 (10%) Query: 6 TGGPPPGPPP--PAGGGGGAGGAGGGPPPGP---PGAGDRGGGGPGGGGPGGGSAGGPSQ 60 T PP PPP P+ G GGPPP P PG G GPG GGP GG G + Sbjct: 158 TSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPK 217 Query: 61 PPGGGGPGI 69 P GGGPG+ Sbjct: 218 P--GGGPGL 224 Score = 55.5 bits (132), Expect = 2e-07 Identities = 31/63 (49%), Positives = 33/63 (52%), Gaps = 5/63 (7%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPP--GG 64 GGPPP PPA G G GP PG P G GG GGGPG + GG +PP GG Sbjct: 182 GGPPP---PPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGG 238 Query: 65 GGP 67 G P Sbjct: 239 GEP 241 Score = 45.4 bits (106), Expect = 2e-04 Identities = 32/77 (41%), Positives = 33/77 (42%), Gaps = 12/77 (15%) Query: 8 GPPPGPPPPAGGGGGAGGA--GGGPPPGPPGAGDRGGGGP----GGGGPGGGSAGGP--- 58 GP PGP G GG GG GG P G PG GG GGG P GG P Sbjct: 193 GPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYH 252 Query: 59 ---SQPPGGGGPGIRKD 72 Q P GGPG R + Sbjct: 253 QQHHQGPPPGGPGGRSE 269 Score = 42.4 bits (98), Expect = 0.002 Identities = 25/63 (39%), Positives = 29/63 (46%), Gaps = 6/63 (9%) Query: 5 STGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGG 64 S+ PP PP G G+G GP P PP A PG P S+G P+ PP Sbjct: 128 SSSAPPATPPT----SGAPPGSGPGPTPTPPPAVT--SAPPGAPPPTPPSSGVPTTPPQA 181 Query: 65 GGP 67 GGP Sbjct: 182 GGP 184 Score = 41.6 bits (96), Expect = 0.003 Identities = 26/61 (42%), Positives = 27/61 (44%), Gaps = 14/61 (22%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGG-------------GPGGGGPGGG 53 GG PG P P GGG G GG P P G G+ GG GP GGPGG Sbjct: 209 GGKMPGGPKP-GGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGR 267 Query: 54 S 54 S Sbjct: 268 S 268 Score = 39.7 bits (91), Expect = 0.010 Identities = 26/64 (40%), Positives = 26/64 (40%), Gaps = 14/64 (21%) Query: 497 GPLCPVGPGPGGPG----PAGPMGPFNPGPFNQGPPGAPPHAGG----------PPPHQY 542 GP GPGPGGP P GP PG G PPH GG PP HQ Sbjct: 195 GPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQ 254 Query: 543 PPQG 546 QG Sbjct: 255 HHQG 258 Score = 38.1 bits (87), Expect = 0.028 Identities = 21/45 (46%), Positives = 21/45 (46%), Gaps = 1/45 (2%) Query: 18 GGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPP 62 GGGGG GG P PPG G GP G GPG P PP Sbjct: 20 GGGGGRGGLHDFRSP-PPGMGLNQNRGPMGPGPGQSGPKPPIPPP 63 Score = 38.1 bits (87), Expect = 0.028 Identities = 26/61 (42%), Positives = 26/61 (42%), Gaps = 13/61 (21%) Query: 15 PPAGGGGGAG-GAGGGPPPGPPGAGDRGGG------GPGGGGPGGGSAGGPSQPPGGGGP 67 PP GGGGG G A G PP G G GG GP GG Q P G GP Sbjct: 632 PPLGGGGGIGYEANPGVPPATMSGSMMGSDMRTERFGQGGAGPVGG------QGPRGMGP 685 Query: 68 G 68 G Sbjct: 686 G 686 Score = 33.9 bits (76), Expect = 0.54 Identities = 24/61 (39%), Positives = 25/61 (40%), Gaps = 11/61 (18%) Query: 9 PPPGP-----PPPAGGGGGAGGAGGGPPPGP--PGAGDRGGGGPGGGGPGGGSAGGPSQP 61 PPP P P A G G A G G PP P A G P G GPG P+ P Sbjct: 99 PPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPT----PTPP 154 Query: 62 P 62 P Sbjct: 155 P 155 Score = 30.8 bits (68), Expect = 4.5 Identities = 28/92 (30%), Positives = 33/92 (35%), Gaps = 27/92 (29%) Query: 396 GPPGPPG-------------GPGMPPGGRGRGRGQGNWGP----PGGEMTFSIPTHKCGL 438 GPP PP GPG P GG+ G + GP PGG P H Sbjct: 183 GPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPK---PPH---- 235 Query: 439 VIGRGGENVKAINQQTGAFVEISRQLPPNGDP 470 RGG + Q + + Q PP G P Sbjct: 236 ---RGGGEPRGGRQHHPPYHQQHHQGPPPGGP 264 Score = 30.8 bits (68), Expect = 4.5 Identities = 35/127 (27%), Positives = 54/127 (42%), Gaps = 23/127 (18%) Query: 297 EMVMDILRERDQG----GFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDA 352 EM + R+R++ G+ D E R+GGG + ++G G G+ + Sbjct: 584 EMEEQMRRQREESYSRMGYMDPRERDMRMGGGGAM-----NMGDPYGSGGQKFPPLGGGG 638 Query: 353 GVRIQFKQDDGTGPEKIA-HIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPG-- 409 G I ++ + G P ++ +MG R E + +GP G G GM PG Sbjct: 639 G--IGYEANPGVPPATMSGSMMGSDMRTERFGQG--------GAGPVGGQGPRGMGPGTP 688 Query: 410 -GRGRGR 415 G GRGR Sbjct: 689 AGYGRGR 695 Score = 30.0 bits (66), Expect = 7.7 Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 9/67 (13%) Query: 41 GGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNST 100 GGG G P G +GG PP GGG GI +A V A + +G D T Sbjct: 614 GGGAMNMGDPYG--SGGQKFPPLGGGGGIGYEA-NPGVPPATMSGSMMGSDM------RT 664 Query: 101 PDFGFGG 107 FG GG Sbjct: 665 ERFGQGG 671 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 80.1 bits (196), Expect = 7e-15 Identities = 189/758 (24%), Positives = 234/758 (30%), Gaps = 150/758 (19%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQP--PGG-- 64 PPGP G G G G PGP GA G+RG G G G G P +P PG Sbjct: 514 PPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARG 573 Query: 65 --GGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQP---- 118 G PG++ A + G + + G G K D +P Sbjct: 574 LTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAG 633 Query: 119 ----ESKKLASQGDSISSQLGPIHPPPRTSMTEEYRV--PDGMVGL-----IIGRGGEQI 167 ++ A D GP+ PP E P G GL G GG+ Sbjct: 634 NAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPG 693 Query: 168 NK-IQQDSGCKVQISP--DSGGLPER-SVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQF 223 ++ + D G + P + G ER +TG P A D +G GP G Sbjct: 694 DQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPD-GPKGSPGPSGTP 752 Query: 224 HDNANGGQNGTVQEIMI-----PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTN 278 D G G E I P G G + KG E G+ L G Sbjct: 753 GDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPT 812 Query: 279 VDK----PLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSV 334 +K P ++G P +G G R E G G P Sbjct: 813 GEKGEPGPRGLVGPP----------------GSRGNPGSRGENGPTGAVGFAGPQGPDGQ 856 Query: 335 GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394 V G GE +K DAG GP+ +A GP H + L Sbjct: 857 PGVKGEPGEPGQK--GDAG---------SPGPQGLAGSPGP-----HGPNGVPGLKGG-- 898 Query: 395 SGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQT 454 G GPPG G PG GR G G PG P G E + Sbjct: 899 RGTQGPPGATGF-PGSAGRVGPPGPAGAPGPAGPLGEP----------GKEGPPGLRGDP 947 Query: 455 GAFVEISRQLP--PNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG------- 505 G+ + + P P G P K G P E+ GP P GP Sbjct: 948 GSHGRVGDRGPAGPPGGPGDK-----GDPG---------EDGQPGPDGPPGPAGTTGQRG 993 Query: 506 -------------PGGPGPAGPMGPFNP--GPFNQGPPG--APPHAGGPPPHQYPPQGWG 548 PG PGPAG G P ++GPPG PP + GP P G Sbjct: 994 IVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAG 1053 Query: 549 NTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPP 608 N P DP A Q PG PGP AP +G+P Sbjct: 1054 ND----GTPGRDGAVGERGDRGDPGPAGLP----GSQGAPG-TPGPVGAPGDAGQRGDPG 1104 Query: 609 QPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPP 668 P G K+ PQ P + + G PG PP Sbjct: 1105 SRGPIGPPGRAG------KRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPG-PP 1157 Query: 669 GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQG 706 G + +A PGP GP+ PP G Sbjct: 1158 GPNGEQGSA-------------GIPGPFGPRGPPGPVG 1182 Score = 77.0 bits (188), Expect = 6e-14 Identities = 178/733 (24%), Positives = 227/733 (30%), Gaps = 214/733 (29%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGG-PGGGGPGG--GSAGGPSQPPGGGG 66 PG P G G G G PPG G G+RG G PG GP G G G P QP G Sbjct: 118 PGLVPVVTGIRGRPGPAG--PPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGP 175 Query: 67 PGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQ 126 PG D + R F Q L+ E L SQ Sbjct: 176 PGHPSHPGPDGLSRP-----------------------FSAQMAGLD-----EKSGLGSQ 207 Query: 127 GDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGG 186 + +GP+ P R P G+ G Q G P G Sbjct: 208 VGLMPGSVGPVGP----------RGPQGLQG--------------QQGGAGPTGPPGEPG 243 Query: 187 LPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAG 246 P + I SRG GPPG+ ++ G+NG E+ AG G Sbjct: 244 DPGP-----------------MGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGF-AGSPG 285 Query: 247 LVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEM----VMDI 302 G + L+ G K ++ P +G P +A M Sbjct: 286 ARGFPGAPGLPGLKGHRGHK-----------GLEGPKGEVGAPGSKGEAGPTGPMGAMGP 334 Query: 303 LRER----DQGGFGDRNEYGSRIGGGID-VPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQ 357 L R ++G G + G R G+ P P +G+ G SG + G++ + Sbjct: 335 LGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIP-GSSG-----FPGNPGMKGE 388 Query: 358 FKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--------PG 409 GPE GP Q +GPPGP G PG+P PG Sbjct: 389 AGPTGARGPE------GPQG-------------QRGETGPPGPVGSPGLPGAIGTDGTPG 429 Query: 410 GRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTG--AFVEISRQLPPN 467 +G G GPPG P + G + I Q G + P Sbjct: 430 AKGPTGSPGTSGPPGSAGPPGSPGPQ-------GSTGPQGIRGQPGDPGVPGFKGEAGPK 482 Query: 468 GDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP----GP-GGPGPAGPMGPFNP-- 520 G+P I+GP+ P G GP G PG GP GP Sbjct: 483 GEPG--------------------PHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERG 522 Query: 521 GPFNQGPPGAP--PHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAA 578 P N+G PG+ P G + P G Q P P +P A N Sbjct: 523 APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPG--- 579 Query: 579 YYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGA 638 Q P G + GP AP GE +P P G I QP G Sbjct: 580 -----VQGPEGKL-GPLGAP------GEDGRPGPPGSIG-----------IRGQPGSMGL 616 Query: 639 PPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGP 698 P + G PG + A R G+ GP GP Sbjct: 617 PGPK--------------------GSSGDPGKPGEAGNAGVPGQRGAPGKDGEV-GPSGP 655 Query: 699 QPPPTQQGQQQAQ 711 PP G++ Q Sbjct: 656 VGPPGLAGERGEQ 668 Score = 67.4 bits (163), Expect = 4e-11 Identities = 176/648 (27%), Positives = 221/648 (34%), Gaps = 144/648 (22%) Query: 6 TGGPP--PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPP 62 T GPP GPP G G G G PG PG G +G GP G PG GP PP Sbjct: 439 TSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGE-PGPHGIQGPIGPP 497 Query: 63 GGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGF-------GGQKRQLED 114 G G G R D +G + + GF G + Q E Sbjct: 498 GEEGKRGPRGD------------PGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGER 545 Query: 115 GDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRV--PDGMVGLIIGRGGEQINKIQQ 172 G S SQGD + G P +T V P+G +G +G GE + Sbjct: 546 GPVGSSGPKGSQGD--PGRPGEPGLPGARGLTGNPGVQGPEGKLG-PLGAPGED-GRPGP 601 Query: 173 DSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQN 232 ++ P S GLP S +G P +A G G PGQ G+ Sbjct: 602 PGSIGIRGQPGSMGLPGPKGS-SGDPGKPGEA----------GNAGVPGQRGAPGKDGEV 650 Query: 233 GTVQEIMIP--AGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPY 290 G + P AG+ G G + L G + G Q + GDP Sbjct: 651 GPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQG--------VPGDP- 701 Query: 291 KVQQACEMVMDILRERDQGGFGDRNEYG-------SRIGGGIDVPVPRHSVGVVIGRSGE 343 V + ++G G+R E G + GG P+ S G G G+ Sbjct: 702 ------GAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPG-PSGTPGD 754 Query: 344 M----IKKIQNDAGVRIQFKQDDGT-GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPP 398 ++ + + G+ GT GP+ +G A ND + L GP Sbjct: 755 TGPPGLQGMPGERGIA-------GTPGPKGDRGGIGEKGAEGTAG---NDGARGL-PGPL 803 Query: 399 GPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFV 458 GPP GP P G +G +G GPPG RG + N TGA V Sbjct: 804 GPP-GPAGPTGEKGEPGPRGLVGPPG----------------SRGNPGSRGENGPTGA-V 845 Query: 459 EISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG-PGP----GGPGPAG 513 + P+G P ++G P + G G PGP G PGP G Sbjct: 846 GFAGPQGPDGQPG-----VKGEPGE------------PGQKGDAGSPGPQGLAGSPGPHG 888 Query: 514 PMG--PFNPGPFNQGPPGA---PPHAG--GPPPHQYPPQGWGNTYPQWQPPAPHDPSKAA 566 P G G QGPPGA P AG GPP P G P +P P Sbjct: 889 PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG---PAGAPGPAGPLGEPGKEGPP---- 941 Query: 567 AAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTG 614 DP SH GP GP P GE QP P G Sbjct: 942 GLRGDPG-------SHGRVGDRGPA-GPPGGPGDKGDPGEDGQPGPDG 981 Score = 67.0 bits (162), Expect = 6e-11 Identities = 174/663 (26%), Positives = 215/663 (32%), Gaps = 130/663 (19%) Query: 10 PPGPPPPAGGGGGAGGAG-----GGP-PPGPPGAGDRGGGGPGGGG-PGGGSAGGPSQPP 62 P GPP AG G G G G P PPGPPG G G PG G PG A GP P Sbjct: 655 PVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEG----GKPGDQGVPGDPGAVGPLGPR 710 Query: 63 GG-GGPGIRKDAFADAVQRARQIAAKIG--------GDAATTVNNSTPDF-GFGGQKRQL 112 G G PG R + + + +A G G + T + P G G++ Sbjct: 711 GERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIA 770 Query: 113 ----EDGDQPESKKLASQG----DSISSQLGPIHPPPRTSMTEEYRVPD--GMVGLIIGR 162 GD+ + ++G D GP+ PP T E P G+VG R Sbjct: 771 GTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSR 830 Query: 163 GGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAP-ESVQKAKMMLDDIVSRGRGGPPG 221 G +G P P+ + G P E QK +G G PG Sbjct: 831 GNPGSRGENGPTGAVGFAGPQG---PDGQPGVKGEPGEPGQKGDAGSPG--PQGLAGSPG 885 Query: 222 QFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK 281 N G G + P G G G G L + G + Sbjct: 886 PHGPNGVPGLKGG-RGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEG----- 939 Query: 282 PLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSVGV--VI 338 P + GDP + V D GG GD+ + G G D P P + G ++ Sbjct: 940 PPGLRGDPGSHGR----VGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIV 995 Query: 339 GRSGEMIKK----IQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394 G G+ ++ + AG + TG + +GPP Sbjct: 996 GMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGE---------- 1045 Query: 395 SGPPGPPGGPGMP--------------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVI 440 GP GP G G P PG G QG G PG P G Sbjct: 1046 PGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPG-------PVGAPGDAG 1098 Query: 441 GRGGENVKAINQQTGAFVEISRQLP----PNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE 496 RG + G + R LP P GD RG Q H + + Sbjct: 1099 QRGDPGSRGPIGPPGRAGK--RGLPGPQGPRGDKGDHGD--RGDRGQKGHRGFTGLQGLP 1154 Query: 497 GPLCPVGPG-----PGGPGPAGPMGPF-------NPGPFNQ-GPPGAPPHAG-----GPP 538 GP P G PG GP GP GP NPGP GPPG G GPP Sbjct: 1155 GPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPP 1214 Query: 539 PHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAP 598 PP PP P P AA D HY + P P+P Sbjct: 1215 GEPGPP----------GPPGP--PGHLTAALGD-------IMGHYDESMPDPLPEFTEDQ 1255 Query: 599 AAP 601 AAP Sbjct: 1256 AAP 1258 Score = 62.8 bits (151), Expect = 1e-09 Identities = 155/624 (24%), Positives = 204/624 (32%), Gaps = 114/624 (18%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPG----GGSAGGPSQPP 62 G P GPP G G G G P GPPG G G PG GS G P Sbjct: 232 GAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPG 291 Query: 63 GGGGPGIRKDAFADAVQRARQIAAKIG--GDAATT----VNNSTPDFGFGGQKRQLEDGD 116 G PG++ ++ + G G+A T G G++ +L G Sbjct: 292 APGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRL--GP 349 Query: 117 QPESKKLASQGDSISSQLGPIHP--PPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDS 174 Q + + G + + GP+ P P +S G G RG E + ++ Sbjct: 350 QGAPGQRGAHG--MPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGET 407 Query: 175 GCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGT 234 G + S GLP ++ G P + S G GPPG + G G+ Sbjct: 408 GPPGPVG--SPGLP-GAIGTDGTPGAKGPTG-------SPGTSGPPGSAGPPGSPGPQGS 457 Query: 235 V--QEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKV 292 Q I G G+ KG K G++ + G + + GDP V Sbjct: 458 TGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPR-----GDPGTV 512 Query: 293 QQACEMVMDILRERDQGGFGDRNEYGSRIGGGID-VPVPRHSVGV--VIGRSGEMIKKIQ 349 G G+R G+R G D +P P+ + G +G SG K Q Sbjct: 513 -------------GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGP--KGSQ 557 Query: 350 NDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPG 409 D G + G + GP + G PG G PG PPG Sbjct: 558 GDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPL-------------GAPGEDGRPG-PPG 603 Query: 410 GRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGD 469 G G+ G PG + + P G+ GE A G Sbjct: 604 SIGIRGQPGSMGLPGPKGSSGDP--------GKPGEAGNA------------------GV 637 Query: 470 PNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFN--QGP 527 P RG+P + GP PVGP PG G G GP P F GP Sbjct: 638 PG-----QRGAPGKDGEV---------GPSGPVGP-PGLAGERGEQGPPGPTGFQGLPGP 682 Query: 528 PGAPPHAGGPPPHQYP--PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQ 585 PG P G P P P G P+ + P + + A H Sbjct: 683 PGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAG--GHGPD 740 Query: 586 QPPG-PVPGPAPAPAAPPA-QGEP 607 P G P P P PP QG P Sbjct: 741 GPKGSPGPSGTPGDTGPPGLQGMP 764 Score = 52.4 bits (124), Expect = 1e-06 Identities = 47/142 (33%), Positives = 55/142 (38%), Gaps = 9/142 (6%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGGGGPGG--GGPG-GGSAG--GPSQP 61 PGPP P G G AG G P GPPG +G G GP G G PG GS G GP P Sbjct: 1154 PGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGP 1213 Query: 62 PGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESK 121 PG GP I + T D K + + G K Sbjct: 1214 PGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLK 1273 Query: 122 KLASQGDSISSQLGPIHPPPRT 143 L+SQ +++ S G P RT Sbjct: 1274 SLSSQIETMRSPDGSKKHPART 1295 Score = 52.0 bits (123), Expect = 2e-06 Identities = 113/430 (26%), Positives = 142/430 (33%), Gaps = 99/430 (23%) Query: 7 GGPPP----GPPPPAGGGGGAGGAGGGPPPGPPGA----GDRGGGGPGGGGPGGGSAGGP 58 G P P G P P G G G GG GPPGA G G GP G G AG Sbjct: 873 GSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPL 932 Query: 59 SQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQP 118 +P G PG+R D + R A GG D G G EDG Sbjct: 933 GEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPG---------DKGDPG-----EDG--- 975 Query: 119 ESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKV 178 Q GP PP T + G+VG+ RG + + +G Sbjct: 976 --------------QPGPDGPPGPAGTTGQ----RGIVGMPGQRGERGMPGLPGPAGTPG 1017 Query: 179 QISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEI 238 ++ P + G P S G GP G ++ G++G V Sbjct: 1018 KVGPTGATGDKGPPGPVGPPGSNGPV----------GEPGPEGPAGNDGTPGRDGAV--- 1064 Query: 239 MIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLR-IIGDPYKVQQACE 297 G+ G G + Q G + G D R IG P + + Sbjct: 1065 ----GERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGL 1120 Query: 298 MVMDILR--ERDQGGFGDRNEYGSRIGGGID-VPVPRHSVGVVIGRSGEMIKKIQNDAGV 354 R + D G GDR + G R G+ +P P G +GE Q AG+ Sbjct: 1121 PGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP-------GPNGE-----QGSAGI 1168 Query: 355 RIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRG 414 F GP +GP S + G PGP G G PPG RG Sbjct: 1169 PGPFGPRGPPGP------VGP----------------SGKEGNPGPLGPIG-PPGVRGSV 1205 Query: 415 RGQGNWGPPG 424 G GPPG Sbjct: 1206 GEAGPEGPPG 1215 Score = 44.3 bits (103), Expect = 4e-04 Identities = 30/72 (41%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Query: 2 SDYSTGGPPP-GPPPPAGGGGGAGGAGGGPPPGPPGA----GDRGGGGPGGGGPGGGSAG 56 +D + G P P GPP PAG G G G GPPG+ G RG GP G G G Sbjct: 793 NDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQG 852 Query: 57 GPSQPPGGGGPG 68 QP G PG Sbjct: 853 PDGQPGVKGEPG 864 Score = 43.5 bits (101), Expect = 7e-04 Identities = 29/69 (42%), Positives = 30/69 (43%), Gaps = 3/69 (4%) Query: 3 DYSTGGP--PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPS 59 D GP PPG P G G G AG PG GA G+RG G G GS G P Sbjct: 1027 DKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPG 1086 Query: 60 QPPGGGGPG 68 P G PG Sbjct: 1087 TPGPVGAPG 1095 Score = 40.4 bits (93), Expect = 0.006 Identities = 32/90 (35%), Positives = 35/90 (38%), Gaps = 23/90 (25%) Query: 1 MSDYSTGGPPPGP-----------PPPAGGGGGAGGAGGGPPPGPPG-AGDRG------- 41 + D GPP GP P P G G AG G G PG G+RG Sbjct: 953 VGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGP 1012 Query: 42 GGGPGGGGPGGGSAG----GPSQPPGGGGP 67 G PG GP G + GP PPG GP Sbjct: 1013 AGTPGKVGPTGATGDKGPPGPVGPPGSNGP 1042 Score = 38.9 bits (89), Expect = 0.017 Identities = 36/103 (34%), Positives = 36/103 (34%), Gaps = 40/103 (38%) Query: 5 STGGP-PPGPPPPAGGGGGAGGAGGGPPPGPPGA-------------------GDRGGGG 44 S G P PGP G G G G P GPPG GDRG G Sbjct: 1081 SQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG 1140 Query: 45 -------------PGGGGPGG--GSAG-----GPSQPPGGGGP 67 PG GP G GSAG GP PPG GP Sbjct: 1141 QKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGP 1183 Score = 37.4 bits (85), Expect = 0.049 Identities = 55/187 (29%), Positives = 60/187 (32%), Gaps = 54/187 (28%) Query: 455 GAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG-PGGPGPAG 513 G + Q P G+ NF RG Q K E L PV G G PGPAG Sbjct: 90 GECCPVCSQTPGGGNTNFG----RGRKGQ----------KGEPGLVPVVTGIRGRPGPAG 135 Query: 514 PMGPFNP----GPFNQ----------GPPGAP--PHAGGPPPHQYPPQGWGNTYPQWQPP 557 P G P GP + G PG P P A GPP H P P Sbjct: 136 PPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHP----------GPD 185 Query: 558 APHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAP----------APAAPPAQGEP 607 P A A D + + GPV P P PP GEP Sbjct: 186 GLSRPFSAQMAGLDEKSGLGSQVG-LMPGSVGPVGPRGPQGLQGQQGGAGPTGPP--GEP 242 Query: 608 PQPPPTG 614 P P G Sbjct: 243 GDPGPMG 249 >gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] Length = 361 Score = 79.7 bits (195), Expect = 9e-15 Identities = 82/350 (23%), Positives = 142/350 (40%), Gaps = 33/350 (9%) Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215 VG IIG+ GE + K++++SG ++ IS G PER ++L G ++ KA M+ D + Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 ++ + +++PA + G +IGKGG IK+++E G ++ + D Sbjct: 83 ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139 Query: 276 NTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSV 334 N + ++ + I G P + + + + ++ E G+ +P P+ S Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLESPP--------------KGVTIPYRPKPSS 184 Query: 335 GVVIGRSGEMIKKIQNDAG-----VRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDL 389 VI G+ +D+ D GP A+ + Sbjct: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQ 244 Query: 390 LQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFS----IPTHKCGLVIGRGGE 445 L +S P G G +G WG T S IP G +IGR G Sbjct: 245 LAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGA 304 Query: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495 + I Q +GA ++I+ + + D + I GS I A+ LI ++ Sbjct: 305 KINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 351 Score = 70.9 bits (172), Expect = 4e-12 Identities = 62/226 (27%), Positives = 94/226 (41%), Gaps = 33/226 (14%) Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393 VG +IG+ GE +KK++ ++G RI + G PE+I + GP + A +I D L+ Sbjct: 25 VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 S PP + +P +CG +IG+GG +K I + Sbjct: 83 ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQ----LIEEKIEGPLCPVGPGPGG 508 TGA V+++ + PN + I G PQ I+ KQ ++E +G P P P Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184 Query: 509 PGP--AGPMGPFNPGPFNQGPPGAP------PHAGGPPPHQYPPQG 546 AG ++ G + P P GPP Y QG Sbjct: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQG 230 Score = 53.5 bits (127), Expect = 7e-07 Identities = 52/193 (26%), Positives = 89/193 (46%), Gaps = 13/193 (6%) Query: 229 GGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIG 287 GG N T+ ++ GK G +IGK GE++K+++E +G ++ + S+ ++ + + G Sbjct: 8 GGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAG 63 Query: 288 DPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKK 347 + +A M++D L E D + SR + + VP G +IG+ G IK+ Sbjct: 64 PTNAIFKAFAMIIDKL-EEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKE 122 Query: 348 IQNDAGVRIQFKQDD-GTGPEKIAHIMG-PPDRCEHAARIINDLLQSLRSG-----PPGP 400 I+ G ++Q D E+ I G P E +I +L+S G P P Sbjct: 123 IRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKP 182 Query: 401 PGGPGMPPGGRGR 413 P + GG+ R Sbjct: 183 SSSPVIFAGGQDR 195 Score = 53.1 bits (126), Expect = 9e-07 Identities = 25/73 (34%), Positives = 47/73 (64%) Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205 + E +P+ ++G IIGR G +IN+I+Q SG +++I+ G +R V++TG+ S+ A+ Sbjct: 285 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 344 Query: 206 MMLDDIVSRGRGG 218 +++ +S GG Sbjct: 345 YLINVRLSSETGG 357 Score = 43.1 bits (100), Expect = 9e-04 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%) Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187 + ISS + R +T VP G +IG+GG +I +I++ +G +VQ++ D L Sbjct: 81 EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138 Query: 188 P---ERSVSLTGAPESV 201 P ER++++ G P+S+ Sbjct: 139 PNSTERAITIAGIPQSI 155 Score = 30.0 bits (66), Expect = 7.7 Identities = 18/71 (25%), Positives = 31/71 (43%) Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385 ++ +P +G +IGR G I +I+ +G +I+ ++ I G A + Sbjct: 287 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 346 Query: 386 INDLLQSLRSG 396 IN L S G Sbjct: 347 INVRLSSETGG 357 >gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] Length = 366 Score = 76.6 bits (187), Expect = 7e-14 Identities = 87/357 (24%), Positives = 150/357 (42%), Gaps = 42/357 (11%) Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215 VG IIG+ GE + K++++SG ++ IS G PER ++L G ++ KA M+ D + Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 ++ + +++PA + G +IGKGG IK+++E G ++ + D Sbjct: 83 ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139 Query: 276 NTNVDKPLRIIGDPYK----VQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-P 330 N + ++ + I G P V+Q C ++++ L + G+ +P P Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLETLSQSPP--------------KGVTIPYRP 184 Query: 331 RHSVGVVIGRSGEMIKKIQNDAG-----VRIQFKQDDGTGPEKIAH-IMG-----PPDRC 379 + S VI G+ +D+ D GP A+ I G PD Sbjct: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 244 Query: 380 EHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRG-QGNWGPPGGEMTFSIPTHKCGL 438 + + + G G G P +G G + E+T IP G Sbjct: 245 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELT--IPNDLIGC 302 Query: 439 VIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495 +IGR G + I Q +GA ++I+ + + D + I GS I A+ LI ++ Sbjct: 303 IIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 356 Score = 68.2 bits (165), Expect = 3e-11 Identities = 62/230 (26%), Positives = 93/230 (40%), Gaps = 37/230 (16%) Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393 VG +IG+ GE +KK++ ++G RI + G PE+I + GP + A +I D L+ Sbjct: 25 VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 S PP + +P +CG +IG+GG +K I + Sbjct: 83 ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIE--------GPLCPVGP 504 TGA V+++ + PN + I G PQ I+ KQ+ +E G P P Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRP 184 Query: 505 GPGGPGP--AGPMGPFNPGPFNQGPPGAP------PHAGGPPPHQYPPQG 546 P AG ++ G + P P GPP Y QG Sbjct: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQG 234 Score = 55.1 bits (131), Expect = 2e-07 Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 17/197 (8%) Query: 229 GGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIG 287 GG N T+ ++ GK G +IGK GE++K+++E +G ++ + S+ ++ + + G Sbjct: 8 GGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAG 63 Query: 288 DPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKK 347 + +A M++D L E D + SR + + VP G +IG+ G IK+ Sbjct: 64 PTNAIFKAFAMIIDKL-EEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKE 122 Query: 348 IQNDAGVRIQFKQDD-GTGPEKIAHIMG-PPDRCEHAARIINDLLQSLRSGP-------- 397 I+ G ++Q D E+ I G P E +I +L++L P Sbjct: 123 IRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPY 182 Query: 398 -PGPPGGPGMPPGGRGR 413 P P P + GG+ R Sbjct: 183 RPKPSSSPVIFAGGQDR 199 Score = 53.1 bits (126), Expect = 9e-07 Identities = 25/73 (34%), Positives = 47/73 (64%) Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205 + E +P+ ++G IIGR G +IN+I+Q SG +++I+ G +R V++TG+ S+ A+ Sbjct: 290 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 349 Query: 206 MMLDDIVSRGRGG 218 +++ +S GG Sbjct: 350 YLINVRLSSETGG 362 Score = 43.1 bits (100), Expect = 9e-04 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%) Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187 + ISS + R +T VP G +IG+GG +I +I++ +G +VQ++ D L Sbjct: 81 EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138 Query: 188 P---ERSVSLTGAPESV 201 P ER++++ G P+S+ Sbjct: 139 PNSTERAITIAGIPQSI 155 Score = 30.0 bits (66), Expect = 7.7 Identities = 18/71 (25%), Positives = 31/71 (43%) Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385 ++ +P +G +IGR G I +I+ +G +I+ ++ I G A + Sbjct: 292 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 351 Query: 386 INDLLQSLRSG 396 IN L S G Sbjct: 352 INVRLSSETGG 362 >gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] Length = 345 Score = 76.6 bits (187), Expect = 7e-14 Identities = 77/329 (23%), Positives = 136/329 (41%), Gaps = 81/329 (24%) Query: 138 HPPPRTSMTEEYRVPDG---------------MVGLIIGRGGEQINKIQQDSGCKVQISP 182 HP P+ E +V +G VG IIG+ GE + K++++SG ++ IS Sbjct: 24 HPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINIS- 82 Query: 183 DSGGLPERSVSLTGAPESVQKAKMML-----DDIVSRGRGGPPGQFHDNANGGQNGTVQE 237 G PER V++TG +++ KA M+ +DI++ P + Sbjct: 83 -EGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATS--------KPPVTLR 133 Query: 238 IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACE 297 +++PA + G +IGKGG IK+++E G ++ + D N + ++ + I G P + Q + Sbjct: 134 LVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN-STERAVTISGTPDAIIQCVK 192 Query: 298 MVMDILRE--RDQGGF-------------------------------GDR-----NEYGS 319 + ++ E QG + G++ +E Sbjct: 193 QICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQ 252 Query: 320 RIGG---GID---------VPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPE 367 + G G+D + +P +G +IGR G I +I+ +G +I+ E Sbjct: 253 NLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSE 312 Query: 368 KIAHIMGPPDRCEHAARIINDLLQSLRSG 396 + I G P A +IN L S +G Sbjct: 313 RQITITGTPANISLAQYLINARLTSEVTG 341 Score = 68.9 bits (167), Expect = 2e-11 Identities = 54/197 (27%), Positives = 87/197 (44%), Gaps = 39/197 (19%) Query: 300 MDILRERDQGGFGDRNEYGSRIG-GGIDVPVPRH------SVGVVIGRSGEMIKKIQNDA 352 + L Q FG R E S++ GG++V + VG +IG+ GE +KK++ ++ Sbjct: 18 LSTLSHHPQPQFGRRME--SKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREES 75 Query: 353 GVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARII-----NDLLQSLRSGPPGPPGGPGMP 407 G RI + G PE+I I GP D A +I D++ S+ + P Sbjct: 76 GARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPAT-------- 125 Query: 408 PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPN 467 P + +P +CG +IG+GG +K I + TGA V+++ + PN Sbjct: 126 -------------SKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN 172 Query: 468 GDPNFKLFIIRGSPQQI 484 + I G+P I Sbjct: 173 STE--RAVTISGTPDAI 187 Score = 67.0 bits (162), Expect = 6e-11 Identities = 75/314 (23%), Positives = 126/314 (40%), Gaps = 45/314 (14%) Query: 227 ANGGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285 + GG N T+ ++ GK G +IGK GET+K+++E +G ++ + S+ ++ + I Sbjct: 38 SEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI----SEGNCPERIVTI 93 Query: 286 IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMI 345 G + +A M+ E D + S+ + + VP G +IG+ G I Sbjct: 94 TGPTDAIFKAFAMIAYKFEE-DIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152 Query: 346 KKIQNDAGVRIQFKQDD-GTGPEKIAHIMGPPDRCEHAARII------------------ 386 K+I+ G ++Q D E+ I G PD + I Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPH 212 Query: 387 ---NDLLQSLRSGPPGPPGGPGMP--PGGRG-----------RGRGQG-NWGPPGGEMTF 429 L Q P PP G P PG + G+ G + PP Sbjct: 213 PDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHEL 272 Query: 430 SIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQ 489 +IP G +IGR G + I Q +GA ++I+ + + + I G+P I A+ Sbjct: 273 TIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSE---RQITITGTPANISLAQY 329 Query: 490 LIEEKIEGPLCPVG 503 LI ++ + +G Sbjct: 330 LINARLTSEVTGMG 343 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/105 (30%), Positives = 60/105 (57%), Gaps = 10/105 (9%) Query: 105 FGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGG 164 F G+K L + E++ L Q + + PP + T E +P+ ++G IIGR G Sbjct: 238 FPGEKLPLHSSE--EAQNLMGQSSGLDAS------PPAS--THELTIPNDLIGCIIGRQG 287 Query: 165 EQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLD 209 +IN+I+Q SG +++I+ + G ER +++TG P ++ A+ +++ Sbjct: 288 TKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 332 >gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] Length = 362 Score = 75.9 bits (185), Expect = 1e-13 Identities = 84/353 (23%), Positives = 147/353 (41%), Gaps = 38/353 (10%) Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215 VG IIG+ GE + K++++SG ++ IS G PER ++L G ++ KA M+ D + Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 ++ + +++PA + G +IGKGG IK+++E G ++ + D Sbjct: 83 ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139 Query: 276 NTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSV 334 N + ++ + I G P + + + + ++ E G+ +P P+ S Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLESPP--------------KGVTIPYRPKPSS 184 Query: 335 GVVIGRSGEMIKKIQNDAG-----VRIQFKQDDGTGPEKIAH-IMG-----PPDRCEHAA 383 VI G+ +D+ D GP A+ I G PD + Sbjct: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQ 244 Query: 384 RIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRG-QGNWGPPGGEMTFSIPTHKCGLVIGR 442 + + G G G P +G G + E+T IP G +IGR Sbjct: 245 LAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELT--IPNDLIGCIIGR 302 Query: 443 GGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495 G + I Q +GA ++I+ + + D + I GS I A+ LI ++ Sbjct: 303 QGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 352 Score = 70.9 bits (172), Expect = 4e-12 Identities = 62/226 (27%), Positives = 94/226 (41%), Gaps = 33/226 (14%) Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393 VG +IG+ GE +KK++ ++G RI + G PE+I + GP + A +I D L+ Sbjct: 25 VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 S PP + +P +CG +IG+GG +K I + Sbjct: 83 ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQ----LIEEKIEGPLCPVGPGPGG 508 TGA V+++ + PN + I G PQ I+ KQ ++E +G P P P Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184 Query: 509 PGP--AGPMGPFNPGPFNQGPPGAP------PHAGGPPPHQYPPQG 546 AG ++ G + P P GPP Y QG Sbjct: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQG 230 Score = 53.5 bits (127), Expect = 7e-07 Identities = 52/193 (26%), Positives = 89/193 (46%), Gaps = 13/193 (6%) Query: 229 GGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIG 287 GG N T+ ++ GK G +IGK GE++K+++E +G ++ + S+ ++ + + G Sbjct: 8 GGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAG 63 Query: 288 DPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKK 347 + +A M++D L E D + SR + + VP G +IG+ G IK+ Sbjct: 64 PTNAIFKAFAMIIDKL-EEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKE 122 Query: 348 IQNDAGVRIQFKQDD-GTGPEKIAHIMG-PPDRCEHAARIINDLLQSLRSG-----PPGP 400 I+ G ++Q D E+ I G P E +I +L+S G P P Sbjct: 123 IRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKP 182 Query: 401 PGGPGMPPGGRGR 413 P + GG+ R Sbjct: 183 SSSPVIFAGGQDR 195 Score = 53.1 bits (126), Expect = 9e-07 Identities = 25/73 (34%), Positives = 47/73 (64%) Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205 + E +P+ ++G IIGR G +IN+I+Q SG +++I+ G +R V++TG+ S+ A+ Sbjct: 286 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 345 Query: 206 MMLDDIVSRGRGG 218 +++ +S GG Sbjct: 346 YLINVRLSSETGG 358 Score = 43.1 bits (100), Expect = 9e-04 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%) Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187 + ISS + R +T VP G +IG+GG +I +I++ +G +VQ++ D L Sbjct: 81 EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138 Query: 188 P---ERSVSLTGAPESV 201 P ER++++ G P+S+ Sbjct: 139 PNSTERAITIAGIPQSI 155 Score = 30.0 bits (66), Expect = 7.7 Identities = 18/71 (25%), Positives = 31/71 (43%) Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385 ++ +P +G +IGR G I +I+ +G +I+ ++ I G A + Sbjct: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 347 Query: 386 INDLLQSLRSG 396 IN L S G Sbjct: 348 INVRLSSETGG 358 >gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 isoform b [Homo sapiens] Length = 556 Score = 75.5 bits (184), Expect = 2e-13 Identities = 88/391 (22%), Positives = 154/391 (39%), Gaps = 75/391 (19%) Query: 113 EDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYR------VPDGMVGLIIGRGGEQ 166 E+ P + A +GD S + G H P TS + VP VG IIG+ G Sbjct: 158 EEVSSPSPPQRAQRGDHSSREQG--HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLT 215 Query: 167 INKIQQDSGCKVQIS-PDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHD 225 I I + + +V I ++ G E+ V++ PE +A M+ +I+ + D Sbjct: 216 IKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEA--------D 267 Query: 226 NANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285 + ++ I+ G G +IGK G +K+++ G K+ + Q+ ++ P R Sbjct: 268 ETKLAEEIPLK-ILAHNGLVGRLIGKEGRNLKKIEHETGTKITI--SSLQDLSIYNPERT 324 Query: 286 IGDPYKVQQACEMVMDILR------ERDQGGFGDRNEYGSRIGGG--------------- 324 I V+ ++I++ E D + Y S + Sbjct: 325 ITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQ 384 Query: 325 --IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTG-PEKIAHIMGPPD-RCE 380 +++ +P +VG +IG+ G IK++ AG I+ +G E++ I GPP+ + + Sbjct: 385 EIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFK 444 Query: 381 HAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFS----IPTHKC 436 RI L + N+ P E+ +P+ Sbjct: 445 AQGRIFGKLKEE--------------------------NFFNPKEEVKLEAHIRVPSSTA 478 Query: 437 GLVIGRGGENVKAINQQTGAFVEISRQLPPN 467 G VIG+GG+ V + T A V + R P+ Sbjct: 479 GRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 509 Score = 71.2 bits (173), Expect = 3e-12 Identities = 52/181 (28%), Positives = 90/181 (49%), Gaps = 15/181 (8%) Query: 133 QLGPI---HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSG-GLP 188 Q GP H P + + +P VG IIG+ G I ++ + +G ++I+P G + Sbjct: 371 QFGPFPHHHSYPEQEIVNLF-IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS 429 Query: 189 ERSVSLTGAPESVQKAK-MMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGL 247 ER V +TG PE+ KA+ + + P + A+ I +P+ AG Sbjct: 430 ERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAH---------IRVPSSTAGR 480 Query: 248 VIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERD 307 VIGKGG+T+ +LQ ++I+ +D + + N + +RIIG + Q A + +I+++ Sbjct: 481 VIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 540 Query: 308 Q 308 Q Sbjct: 541 Q 541 Score = 63.9 bits (154), Expect = 5e-10 Identities = 71/277 (25%), Positives = 123/277 (44%), Gaps = 36/277 (12%) Query: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQIS---PDSGGLPERSVSLTGAPESVQKAKMML- 208 +G+VG +IG+ G + KI+ ++G K+ IS S PER++++ G E+ A++ + Sbjct: 283 NGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIM 342 Query: 209 ---------DDIVSRGRGG------PPGQF----HDNANGGQNGTVQEIMIPAGKAGLVI 249 D + G P QF H ++ Q + + IP G +I Sbjct: 343 KKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQE--IVNLFIPTQAVGAII 400 Query: 250 GKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQ-QACEMVMDILRERDQ 308 GK G IKQL AG + + ++ +V + + II P + Q +A + L+E + Sbjct: 401 GKKGAHIKQLARFAGASIKIAP--AEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE--E 456 Query: 309 GGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQN--DAGVRIQFKQDDGTGP 366 F + E + + VP + G VIG+ G+ + ++QN A V + Q Sbjct: 457 NFFNPKEE----VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENE 512 Query: 367 EKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGG 403 E I I+G + A R I +++Q ++ P G Sbjct: 513 EVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQG 549 Score = 33.1 bits (74), Expect = 0.92 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 13/102 (12%) Query: 401 PGGPGMPPGGRGRGRGQGNWGPPGGE---------MTFSIPTHKCGLVIGRGGENVKAIN 451 P P G R QG+ PGG + +PT G +IG+ G +K I Sbjct: 163 PSPPQRAQRGDHSSREQGH--APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNIT 220 Query: 452 QQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE 493 +QT + V+I R+ N K I +P+ A ++I E Sbjct: 221 KQTQSRVDIHRK--ENSGAAEKPVTIHATPEGTSEACRMILE 260 >gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] Length = 335 Score = 75.5 bits (184), Expect = 2e-13 Identities = 84/346 (24%), Positives = 146/346 (42%), Gaps = 51/346 (14%) Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215 VG IIG+ GE + K++++SG ++ IS G PER ++L G ++ KA M+ D + Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 ++ + +++PA + G +IGKGG IK+++E G ++ + D Sbjct: 83 ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139 Query: 276 NTNVDKPLRIIGDPYK----VQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-P 330 N + ++ + I G P V+Q C ++++ L + G+ +P P Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLETLSQSPP--------------KGVTIPYRP 184 Query: 331 RHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLL 390 + S VI G+ IQ + Q D T ++A + Sbjct: 185 KPSSSPVIFAGGQAY-TIQGQYAI----PQPDLTKLHQLA---------------MQQSH 224 Query: 391 QSLRSGPPGPPGGPGMPPGGRGRGRG-QGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKA 449 + G G G P +G G + E+T IP G +IGR G + Sbjct: 225 FPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELT--IPNDLIGCIIGRQGAKINE 282 Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495 I Q +GA ++I+ + + D + I GS I A+ LI ++ Sbjct: 283 IRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 325 Score = 66.6 bits (161), Expect = 7e-11 Identities = 53/190 (27%), Positives = 83/190 (43%), Gaps = 29/190 (15%) Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393 VG +IG+ GE +KK++ ++G RI + G PE+I + GP + A +I D L+ Sbjct: 25 VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 S PP + +P +CG +IG+GG +K I + Sbjct: 83 ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512 TGA V+++ + PN + I G PQ I+ KQ+ +E + P P Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLE----TLSQSP----PK 176 Query: 513 GPMGPFNPGP 522 G P+ P P Sbjct: 177 GVTIPYRPKP 186 Score = 53.1 bits (126), Expect = 9e-07 Identities = 25/73 (34%), Positives = 47/73 (64%) Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205 + E +P+ ++G IIGR G +IN+I+Q SG +++I+ G +R V++TG+ S+ A+ Sbjct: 259 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 318 Query: 206 MMLDDIVSRGRGG 218 +++ +S GG Sbjct: 319 YLINVRLSSETGG 331 Score = 43.1 bits (100), Expect = 9e-04 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%) Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187 + ISS + R +T VP G +IG+GG +I +I++ +G +VQ++ D L Sbjct: 81 EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138 Query: 188 P---ERSVSLTGAPESV 201 P ER++++ G P+S+ Sbjct: 139 PNSTERAITIAGIPQSI 155 Score = 30.0 bits (66), Expect = 7.7 Identities = 18/71 (25%), Positives = 31/71 (43%) Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385 ++ +P +G +IGR G I +I+ +G +I+ ++ I G A + Sbjct: 261 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 320 Query: 386 INDLLQSLRSG 396 IN L S G Sbjct: 321 INVRLSSETGG 331 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 75.5 bits (184), Expect = 2e-13 Identities = 91/325 (28%), Positives = 105/325 (32%), Gaps = 98/325 (30%) Query: 396 GPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTG 455 GPP PPG P PP P GG N+ G Sbjct: 49 GPPPPPGKPQGPP-------------PQGG-------------------------NKPQG 70 Query: 456 AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPM 515 PP G P +G P Q D K P P G P GP P G Sbjct: 71 P--------PPPGKP-------QGPPPQGD--------KSRSPRSPPGK-PQGPPPQGGN 106 Query: 516 GPFNPGPFNQGPPGAPPHAG----GPP----PHQYPPQGWGNTYPQWQPPAPHDPSKAAA 567 P P P P G PP G GPP P PPQG + P+ P P P Sbjct: 107 QPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG 166 Query: 568 AAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQ-PPPTGQSDYTKAWEEYY 626 QP GP P P PP G+ PQ PPP G+ + Sbjct: 167 -----------------NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKS 209 Query: 627 KKIGQQPQQPGAPPQQDYTKAW---EEYYKKQAQVATGGG--PGAPPGSQPDYSAAWAEY 681 + P +P PP Q + K Q GG G PP +P A Sbjct: 210 RSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGS 269 Query: 682 YRQQAAYYGQTPGPGGPQPPPTQQG 706 Q A ++P PG PQ PP Q+G Sbjct: 270 KSQSA----RSP-PGKPQGPPQQEG 289 Score = 74.7 bits (182), Expect = 3e-13 Identities = 76/245 (31%), Positives = 87/245 (35%), Gaps = 88/245 (35%) Query: 501 PVGPGP-GGPGPAGPMGPFNP-GPFNQG------------PPGAPPHAG----GPPPHQY 542 P GP P GG P GP P P GP QG P G PP G GPPP Sbjct: 57 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG 116 Query: 543 PPQG---WGNTYPQWQPPA--PHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPA 597 PQG G PQ PP P P + P + PPG GP P Sbjct: 117 KPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRS------------PPGKPQGPPPQ 164 Query: 598 -----PAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQP-------GAPPQQDYT 645 PP G+P PPP G G++PQ P G PPQ D + Sbjct: 165 GGNQPQGPPPPPGKPQGPPPQG---------------GKKPQGPPPPGKPQGPPPQGDKS 209 Query: 646 KAWEEYYKKQAQVATGGGPGAPP--GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPT 703 ++ +Q G G PP G+QP G P PG PQ PP Sbjct: 210 RS--------SQSPPGKPQGPPPQGGNQPQ----------------GPPPPPGKPQGPPP 245 Query: 704 QQGQQ 708 Q G + Sbjct: 246 QGGNK 250 Score = 70.5 bits (171), Expect = 5e-12 Identities = 68/224 (30%), Positives = 79/224 (35%), Gaps = 43/224 (19%) Query: 502 VGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAG----GPP----PHQYPPQGWGNTYPQ 553 + P GP P G P P P P G PP G GPP P PPQG + P+ Sbjct: 32 IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91 Query: 554 WQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAP----APAAPPAQGEPPQ 609 P P P P PPG GP P P PP G+P Sbjct: 92 SPPGKPQGP--PPQGGNQPQGP---------PPPPGKPQGPPPQGGNRPQGPPPPGKPQG 140 Query: 610 PPPTGQSDYTKAW-----EEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGP 664 PPP G + + + G QPQ P PP + + K Q G Sbjct: 141 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200 Query: 665 GAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708 G PP Q D S + Q+P PG PQ PP Q G Q Sbjct: 201 GPPP--QGDKSRS------------SQSP-PGKPQGPPPQGGNQ 229 Score = 61.2 bits (147), Expect = 3e-09 Identities = 81/252 (32%), Positives = 94/252 (37%), Gaps = 66/252 (26%) Query: 396 GPPGPPGGP-GMPPGGRGRGRGQGNWG-----PPGGEMTFSIPTHKCGLVIG---RGGEN 446 GPP PPG P G PP G R +G G PP G+ + S P G G +GG Sbjct: 110 GPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRS-PRSPPGKPQGPPPQGG-- 166 Query: 447 VKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGP 506 NQ G PP G P +G P Q +K +GP P P Sbjct: 167 ----NQPQGP-------PPPPGKP-------QGPPPQGG-------KKPQGP--PPPGKP 199 Query: 507 GGPGPAGPMGPFNPGPFNQGPPGAPPHAG----GPPPHQYPPQG---WGNTYPQWQPPA- 558 GP P G + P + P G PP G GPPP PQG G PQ PP Sbjct: 200 QGPPPQGDKSRSSQSPPGK-PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 258 Query: 559 -PHDP-----SKAAAAAADPNAAWAA--YYSHYYQQPPGPVPGPAPAPAAPPA------- 603 P P SK+ +A + P + Q PP P G P APPA Sbjct: 259 KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP 318 Query: 604 ---QGEPPQPPP 612 QG P PP Sbjct: 319 RPPQGGRPSRPP 330 Score = 47.4 bits (111), Expect = 5e-05 Identities = 29/68 (42%), Positives = 30/68 (44%), Gaps = 12/68 (17%) Query: 8 GPPPGP-----PPPAGGGGGAGGAGGGPPPGPPGAGDRG------GGGPGGGGP-GGGSA 55 GPPP P PPP GG G G P GPP GD+ G P G P GG Sbjct: 49 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 108 Query: 56 GGPSQPPG 63 GP PPG Sbjct: 109 QGPPPPPG 116 Score = 47.4 bits (111), Expect = 5e-05 Identities = 29/68 (42%), Positives = 30/68 (44%), Gaps = 12/68 (17%) Query: 8 GPPPGP-----PPPAGGGGGAGGAGGGPPPGPPGAGDRG------GGGPGGGGP-GGGSA 55 GPPP P PPP GG G G P GPP GD+ G P G P GG Sbjct: 110 GPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 169 Query: 56 GGPSQPPG 63 GP PPG Sbjct: 170 QGPPPPPG 177 Score = 47.4 bits (111), Expect = 5e-05 Identities = 31/74 (41%), Positives = 34/74 (45%), Gaps = 13/74 (17%) Query: 7 GGPPPGPP--PPAGGGGGAGGAGGGP--PPGPP---GAGDRGGGGPGGGGPG------GG 53 G PPPG P PPA GG + A P P GPP G +G P GG P G Sbjct: 253 GPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG 312 Query: 54 SAGGPSQPPGGGGP 67 GP +PP GG P Sbjct: 313 QPQGPPRPPQGGRP 326 Score = 47.0 bits (110), Expect = 6e-05 Identities = 31/73 (42%), Positives = 32/73 (43%), Gaps = 16/73 (21%) Query: 7 GGPPPGPPPPAGGGGGAGGAGG----GPPP-----GPPGAGDRG------GGGPGGGGP- 50 G P GPPPP G G GG GPPP GPP GD+ G P G P Sbjct: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQ 225 Query: 51 GGGSAGGPSQPPG 63 GG GP PPG Sbjct: 226 GGNQPQGPPPPPG 238 Score = 46.2 bits (108), Expect = 1e-04 Identities = 29/77 (37%), Positives = 29/77 (37%), Gaps = 16/77 (20%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGG-------GPGGGSAGGPS 59 G P GPPPP G G GG P GPP G G GG P G G P Sbjct: 227 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286 Query: 60 Q---------PPGGGGP 67 Q PP GG P Sbjct: 287 QEGNNPQGPPPPAGGNP 303 Score = 45.8 bits (107), Expect = 1e-04 Identities = 43/130 (33%), Positives = 46/130 (35%), Gaps = 21/130 (16%) Query: 2 SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPP-GAGDRGGGGPGGGGPGGGSAGGPSQ 60 S S G P GPPP GG G PPPG P G +GG P G P G P Sbjct: 211 SSQSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQG 262 Query: 61 PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNN---STPDFGFGGQKRQLEDGDQ 117 PP GG Q AR K G NN P G Q+ Q Q Sbjct: 263 PPAQGG---------SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 313 Query: 118 PESKKLASQG 127 P+ QG Sbjct: 314 PQGPPRPPQG 323 Score = 41.2 bits (95), Expect = 0.003 Identities = 26/62 (41%), Positives = 29/62 (46%), Gaps = 8/62 (12%) Query: 7 GGPPPGP---PPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 G PPPG PPP G + + G P GPP +GG P G P G GP PP Sbjct: 70 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGP--PPQ 124 Query: 64 GG 65 GG Sbjct: 125 GG 126 Score = 41.2 bits (95), Expect = 0.003 Identities = 26/62 (41%), Positives = 29/62 (46%), Gaps = 8/62 (12%) Query: 7 GGPPPGP---PPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 G PPPG PPP G + + G P GPP +GG P G P G GP PP Sbjct: 131 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGP--PPQ 185 Query: 64 GG 65 GG Sbjct: 186 GG 187 Score = 40.8 bits (94), Expect = 0.004 Identities = 26/60 (43%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 2 SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPP-GAGDRGGGGPGGGGPGGGSAGGPSQ 60 S S G P GPPP GG G PPPG P G +GG P G P G G P Q Sbjct: 89 SPRSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQ 144 Score = 40.0 bits (92), Expect = 0.007 Identities = 26/60 (43%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 2 SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPG-PPGAGDRGGGGPGGGGPGGGSAGGPSQ 60 S S G P GPPP GG G PPPG P G +GG P G P G G P Q Sbjct: 150 SPRSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ 205 Score = 36.6 bits (83), Expect = 0.083 Identities = 23/54 (42%), Positives = 24/54 (44%), Gaps = 5/54 (9%) Query: 8 GPPPGPPPPAGGGGGAGGAGGGPPPGPP-GAGDRGGGGPGGGGPGGGSAGGPSQ 60 G P GP P GG G PPPG P G +GG P G P G G P Q Sbjct: 34 GNPQGPSPQ----GGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83 >gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] Length = 331 Score = 74.7 bits (182), Expect = 3e-13 Identities = 81/342 (23%), Positives = 143/342 (41%), Gaps = 47/342 (13%) Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215 VG IIG+ GE + K++++SG ++ IS G PER ++L G ++ KA M+ D + Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 ++ + +++PA + G +IGKGG IK+++E G ++ + D Sbjct: 83 ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139 Query: 276 NTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSV 334 N + ++ + I G P + + + + ++ E G+ +P P+ S Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLESPP--------------KGVTIPYRPKPSS 184 Query: 335 GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394 VI G+ IQ + Q D T ++A + + Sbjct: 185 SPVIFAGGQAY-TIQGQYAI----PQPDLTKLHQLA---------------MQQSHFPMT 224 Query: 395 SGPPGPPGGPGMPPGGRGRGRG-QGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 G G G P +G G + E+T IP G +IGR G + I Q Sbjct: 225 HGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELT--IPNDLIGCIIGRQGAKINEIRQM 282 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495 +GA ++I+ + + D + I GS I A+ LI ++ Sbjct: 283 SGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 321 Score = 69.7 bits (169), Expect = 9e-12 Identities = 53/190 (27%), Positives = 82/190 (43%), Gaps = 33/190 (17%) Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393 VG +IG+ GE +KK++ ++G RI + G PE+I + GP + A +I D L+ Sbjct: 25 VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 S PP + +P +CG +IG+GG +K I + Sbjct: 83 ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512 TGA V+++ + PN + I G PQ I+ KQ+ +E P P Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESP------------PK 172 Query: 513 GPMGPFNPGP 522 G P+ P P Sbjct: 173 GVTIPYRPKP 182 Score = 53.1 bits (126), Expect = 9e-07 Identities = 25/73 (34%), Positives = 47/73 (64%) Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205 + E +P+ ++G IIGR G +IN+I+Q SG +++I+ G +R V++TG+ S+ A+ Sbjct: 255 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 314 Query: 206 MMLDDIVSRGRGG 218 +++ +S GG Sbjct: 315 YLINVRLSSETGG 327 Score = 43.1 bits (100), Expect = 9e-04 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%) Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187 + ISS + R +T VP G +IG+GG +I +I++ +G +VQ++ D L Sbjct: 81 EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138 Query: 188 P---ERSVSLTGAPESV 201 P ER++++ G P+S+ Sbjct: 139 PNSTERAITIAGIPQSI 155 Score = 30.0 bits (66), Expect = 7.7 Identities = 18/71 (25%), Positives = 31/71 (43%) Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385 ++ +P +G +IGR G I +I+ +G +I+ ++ I G A + Sbjct: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 316 Query: 386 INDLLQSLRSG 396 IN L S G Sbjct: 317 INVRLSSETGG 327 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 73.2 bits (178), Expect = 8e-13 Identities = 101/355 (28%), Positives = 121/355 (34%), Gaps = 91/355 (25%) Query: 396 GPPGPPGGPGMP-----PGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGE 445 GPPGP G PG+P PG GR +G GPPG GE F++P G Sbjct: 710 GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP----------GPP 759 Query: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG 505 + GA L P GD RG P + + + GP VGP Sbjct: 760 GPPGLPGFKGA-------LGPKGD--------RGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 506 PGGPGPAGPMG------------PFNPGPFNQ----------GPPGAPP-HAGGPPPHQY 542 G PGP GP G P PGP Q G PG P GPP + Sbjct: 805 -GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863 Query: 543 PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPP 602 P G P P +P P KA A+ PPGP PGP P Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG-----PPGP-PGPLGIPGRSG 917 Query: 603 A---------QGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK 653 QG+P P PTG+ K +P PG P D Sbjct: 918 VPGLKGDDGLQGQPGLPGPTGE-----------KGSKGEPGLPGPPGPMD-----PNLLG 961 Query: 654 KQAQVATGGGPGAPPGSQP-DYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQ 707 + + G PG P S P Y + + + PGP GP+ P GQ Sbjct: 962 SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016 Score = 65.9 bits (159), Expect = 1e-10 Identities = 190/754 (25%), Positives = 243/754 (32%), Gaps = 180/754 (23%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69 PGPP P G G G G PG PG G G GP G G+ G P G PG+ Sbjct: 83 PGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142 Query: 70 RKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDS 129 + + + G+ + + +S P G K P + L Sbjct: 143 QGPPGPPGIPGMK-------GEPGSIIMSSLP-----GPKGNPGYPGPPGIQGLPGP-TG 189 Query: 130 ISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPE 189 I +GP PP P G GL +G +N Q G K + G P Sbjct: 190 IPGPIGPPGPPGLMG-------PPGPPGLPGPKGNMGLN-FQGPKGEKGEQGLQ--GPP- 238 Query: 190 RSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVI 249 G P + + K +D +G G PG D G G I P G G Sbjct: 239 ------GPPGQISEQKRPIDVEFQKGDQGLPG---DRGPPGPPG----IRGPPGPPGGEK 285 Query: 250 GKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDP-YKVQQACEMVMDILRERDQ 308 G+ GE Q G + +DG +N P + GDP Y + R+ ++ Sbjct: 286 GEKGE-----QGEPGKRGKPGKDG-ENGQPGIP-GLPGDPGYPGEPG--------RDGEK 330 Query: 309 GGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEM-IKKIQNDAGVRIQFKQDDGTGPE 367 G GD G + +PR G+ IG G + + + + G R Sbjct: 331 GQKGDTGPPGPP-----GLVIPRPGTGITIGEKGNIGLPGLPGEKGER------------ 373 Query: 368 KIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPG----GPGMPPGGRGRGRGQGNWGPP 423 I GPP G PGPPG GP PPG G +G+ GPP Sbjct: 374 GFPGIQGPP-------------------GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414 Query: 424 GGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSP-- 481 G SIP GL G + G + S ++ G P GSP Sbjct: 415 G----ISIPGPP-GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP-----GSPGD 464 Query: 482 -----------QQIDHAKQLIEEKIEGPLCPVGPG-PGGPGPAGPMG-PFNPGPFNQ--- 525 + D I I GP P PG PG PGP G +G P G Q Sbjct: 465 KGLQGEQGVKGDKGDTCFNCIGTGISGP--PGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522 Query: 526 -GPPGAPPHAGGPPPHQYP------------PQGWGNTYPQWQPPAPHDPSKAAAAAADP 572 GP G P G P +P P G+ P AP P D Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582 Query: 573 NAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE--PPQPP-------------PTGQSD 617 PG +PGP P +GE PP P P G Sbjct: 583 L--------------PG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627 Query: 618 YTKAWEEYYKKIGQQPQQPGAP-----PQQDYTKAWEEYYK----KQAQVATGGGPGAPP 668 E+ + + P QPG P P Q T+ + + V G PG P Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP- 686 Query: 669 GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPP 702 QP G PGP GP+ P Sbjct: 687 -GQPGLPGIPGSKGEPGIPGIG-LPGPPGPKGFP 718 Score = 62.4 bits (150), Expect = 1e-09 Identities = 205/819 (25%), Positives = 262/819 (31%), Gaps = 228/819 (27%) Query: 10 PPGPPPPAGGGGGAGGAGGGP-----------PPGPPGA--------------------G 38 PPGPP G G G GP PPGPPG G Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 39 DRGGGGPGG-----GGPGG--GSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGD 91 DRG GP G G PGG G G +P G PG K G + Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG------------------KDGEN 306 Query: 92 AATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRV 151 + D G+ G+ + DG++ + G G + P P T +T + Sbjct: 307 GQPGIPGLPGDPGYPGEPGR--DGEKGQKGDTGPPGPP-----GLVIPRPGTGITIGEKG 359 Query: 152 PDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDI 211 G+ GL +G IQ G G P +V P + Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLP--------GPPGAAVMGPPGPPGFPGERGQ---- 407 Query: 212 VSRGRGGPPGQFHDNANG--GQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMIL 269 +G GPPG G GQ G + P G AG I E + Sbjct: 408 --KGDEGPPGISIPGPPGLDGQPGA-PGLPGPPGPAGPHIPPSDEICEPGPP-------- 456 Query: 270 IQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR-IGGGIDVP 328 G + DK L + +QG GD+ + IG GI P Sbjct: 457 ---GPPGSPGDKGL---------------------QGEQGVKGDKGDTCFNCIGTGISGP 492 Query: 329 VPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDR--CEHAARII 386 + + + G G + G + + Q TGP+ + I G P + Sbjct: 493 PGQPGLPGLPGPPGSL-----GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEP 547 Query: 387 NDLL-------QSLRSGPPGPPGGPGMP-----------PGGRGRGRG---QGNWGPPGG 425 D+L G PG PG PG+P PG +G G +G GPPG Sbjct: 548 GDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN 607 Query: 426 EMTFSIPTH----------KCGLVIGRGGENVKAINQQTGAFVEISRQLP-PNGDPNFKL 474 +P + G V +G + V Q G +P P GDP + Sbjct: 608 PGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG--------IPGPKGDPG-QT 658 Query: 475 FIIRGSPQQIDHAKQLIEEKIEG-PLCPVGPG-PGGPGPAGPMG------PFNPGPFN-- 524 G P + + + + G P P PG PG PG G G P PGP Sbjct: 659 ITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFP 718 Query: 525 --QGPPGAPPHAG-----GPP-PHQYP-PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAA 575 GPPGAP G GPP P +P P+G P + P P P A Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG----EPGFALPGPPGPPGLPGF----KGA 770 Query: 576 WAAYYSHYYQQPPGP--------VPGP--------APAPAAPP------AQGEPPQPP-- 611 + PPGP +PGP P P PP QG PP PP Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG-PPGPPGI 829 Query: 612 --PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPG 669 P GQ I + PG PP D E + + GP PPG Sbjct: 830 PGPIGQPG--------LHGIPGEKGDPG-PPGLDVPGPPGE--RGSPGIPGAPGPIGPPG 878 Query: 670 SQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQG 706 S A A + G PGP GP P + G Sbjct: 879 SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917 Score = 60.5 bits (145), Expect = 5e-09 Identities = 101/346 (29%), Positives = 123/346 (35%), Gaps = 55/346 (15%) Query: 395 SGPPGPPGGPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGEN--- 446 SGPPG PG PG PG G G G GPPG G+ P + G G N Sbjct: 1136 SGPPGNPGLPG-EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194 Query: 447 --VKAINQQTG----AFVEISRQLP-PNGDPNFKLFI-IRGSPQQIDHAKQLIEEKIEGP 498 + ++ Q G + + LP P G+P F F ++G P +E +G Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGP-KGN 1253 Query: 499 LCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAG-----GPPPHQYPPQGWGNTYPQ 553 P GP PG PGP G G PGP +GPPG P + G G P P G Q Sbjct: 1254 PGPQGP-PGRPGPTGFQG--LPGP--EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1308 Query: 554 WQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPP-- 611 P +P + + + P VPG A P P PP PP Sbjct: 1309 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA-GPEGEPGLIGPPGPPGL 1367 Query: 612 --PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAP-P 668 P+GQS K + I QP G P Q Q G PG P Sbjct: 1368 PGPSGQSIIIKG-DAGPPGIPGQPGLKGLPGPQG----------PQGLPGPTGPPGDPGR 1416 Query: 669 GSQPDYSAAWAEYYRQQAAYYGQ--------TPGPGGPQPPPTQQG 706 P + A + GQ PGP G Q PP G Sbjct: 1417 NGLPGFDGAGGR--KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460 Score = 59.7 bits (143), Expect = 9e-09 Identities = 176/686 (25%), Positives = 216/686 (31%), Gaps = 172/686 (25%) Query: 10 PPGPPPPAGGGGGAG--------GAGGGPP-PGPPGAGDRGGGGPGG-----GGPGGGSA 55 PPGPP G G G G G P PGPPG +G GP G G PG Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGI--QGLPGPTGIPGPIGPPGPPGL 202 Query: 56 GGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDG 115 GP PPG GP K Q + + G G G Q+ + Sbjct: 203 MGPPGPPGLPGP---KGNMGLNFQGPKGEKGEQGLQ------------GPPGPPGQISEQ 247 Query: 116 DQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSG 175 +P + + GP PP R P G G G GEQ ++ Sbjct: 248 KRPIDVEFQKGDQGLPGDRGPPGPP-------GIRGPPGPPGGEKGEKGEQGEPGKRGKP 300 Query: 176 CK--VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNG 233 K P GLP G P GR G GQ D G G Sbjct: 301 GKDGENGQPGIPGLP-GDPGYPGEP----------------GRDGEKGQKGDTGPPGPPG 343 Query: 234 TVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKV 292 ++IP G+ IG+ G G+ + + G + + P + G P Sbjct: 344 ----LVIPRPGTGITIGEKG--------NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391 Query: 293 QQACEMVMDILRERDQGGFGDRNEYGSRIGG--GID-------VPVPRHSVGVVIGRSGE 343 ER Q GD G I G G+D +P P G I S E Sbjct: 392 VMGPPGPPGFPGERGQK--GDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 344 MI-------------KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLL 390 + K +Q + GV K D G D C + + Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGV----KGDKG-------------DTCFNC-------I 485 Query: 391 QSLRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVK 448 + SGPPG PG PG+ PPG G +G G G +P G+ G Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP----GIPGAPGAPGFP 541 Query: 449 AINQQTGAFVEI------SRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE------ 496 + G + +L G P L + G+P Q D L K E Sbjct: 542 GSKGEPGDILTFPGMKGDKGELGSPGAPG--LPGLPGTPGQ-DGLPGLPGPKGEPGGITF 598 Query: 497 ----GPLCPVGPG-PGGPGPAGPMGPFN---PGPF----------NQGPPGAPPHAGGP- 537 GP P PG PG PG GPMGP PGP N G PG P G P Sbjct: 599 KGERGP--PGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656 Query: 538 -----PPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGP-- 590 P P G P P P + + PPGP Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716 Query: 591 ---VPGPAPAPAAPPAQG--EPPQPP 611 +PGP AP P G PP PP Sbjct: 717 FPGIPGPPGAPGTPGRIGLEGPPGPP 742 Score = 58.2 bits (139), Expect = 3e-08 Identities = 79/282 (28%), Positives = 92/282 (32%), Gaps = 80/282 (28%) Query: 396 GPPGPPGGPGMPPGGRGRGRGQ-GNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKA 449 GPPGP G PG+P GQ G GPPG G+M F P G Sbjct: 1003 GPPGPKGNPGLP--------GQPGLIGPPGLKGTIGDMGFPGPQGV------EGPPGPSG 1048 Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDH-------AKQLIEEKIEGPLCPV 502 + Q G+ + Q GDP + G P I+ + P P Sbjct: 1049 VPGQPGS-PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG 1107 Query: 503 GPG-------------PGGPGPAGPMG----PFNPG-PFNQGPPGAPPHAG--GPPPHQY 542 PG PG PGP GP G P NPG P GP G H G GPP + Sbjct: 1108 LPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKG 1167 Query: 543 PP-----------------QGWGNTYPQWQP---------PAPHDPSKAAAAAADPNAAW 576 P G+GN P P P P + Sbjct: 1168 KPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF 1227 Query: 577 AAYYSHYYQQPPGPVPGPAPAPAAPPA----QGEPPQPPPTG 614 + Q PPGP P PA P QG P +P PTG Sbjct: 1228 HGFPG--VQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTG 1267 Score = 52.4 bits (124), Expect = 1e-06 Identities = 89/340 (26%), Positives = 105/340 (30%), Gaps = 97/340 (28%) Query: 396 GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447 GP GPPG PG+P PG +G G GPPG IP GR G V Sbjct: 872 GPIGPPGSPGLPGKAGASGFPGTKGE---MGMMGPPGPPGPLGIP--------GRSG--V 918 Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP--G 505 + G ++G P + GP G Sbjct: 919 PGLKGDDG---------------------LQGQP------------GLPGPTGEKGSKGE 945 Query: 506 PGGPGPAGPMGPFNPGPFNQ-GPPGAP--PHAGGPPPHQYPPQGWGNTYPQWQP--PAPH 560 PG PGP GPM P G + G PG P P GP +Q P G QP P P Sbjct: 946 PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005 Query: 561 DPSKAAAAAADPNAAWAAYYSHYYQQP--PGP-----VPGPAPAPAAPPAQGEPPQPPPT 613 P P PGP PGP+ P P + G P Q Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065 Query: 614 GQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAP--PGS- 670 G + +P PG P + V G PG P PG+ Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGI----------KGSVGDPGLPGLPGTPGAK 1115 Query: 671 -QPDYSAAWAEYYRQQAAYYGQTPGPGGPQ---PPPTQQG 706 QP + TPGP GP+ PP G Sbjct: 1116 GQPGLPG------------FPGTPGPPGPKGISGPPGNPG 1143 Score = 47.0 bits (110), Expect = 6e-05 Identities = 95/358 (26%), Positives = 114/358 (31%), Gaps = 72/358 (20%) Query: 365 GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGP-- 422 GP I + G P ++ S GP G PG PG PPG +G G GP Sbjct: 147 GPPGIPGMKGEP----------GSIIMSSLPGPKGNPGYPG-PPGIQGLPGPTGIPGPIG 195 Query: 423 PGGEMTFSIPTHKCGLVIGRG--GENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS 480 P G P GL +G G N + + G E Q PP G Sbjct: 196 PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG---EQGLQGPP------------GP 240 Query: 481 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH 540 P QI K+ I+ + + + G PGP G GP PGP G G G P Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP--PGP-PGGEKGEKGEQGEPGKR 297 Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA 600 P + N P P P DP D PPGP P P Sbjct: 298 GKPGKDGENGQP-GIPGLPGDPGYPGEPGRDGEKGQKGDTG-----PPGPPGLVIPRPGT 351 Query: 601 PPAQGE------PPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK- 653 GE P P G E + I P PG P + Sbjct: 352 GITIGEKGNIGLPGLPGEKG--------ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403 Query: 654 KQAQVATGGGPG----APPG--SQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQ 705 ++ Q G PG PPG QP A PGP GP PP+ + Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPG------------APGLPGPPGPAGPHIPPSDE 449 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/63 (44%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69 PGPP P G G G G PPG G GD G GP G G +G P QP G PG Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061 Query: 70 RKD 72 + D Sbjct: 1062 KGD 1064 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/76 (43%), Positives = 34/76 (44%), Gaps = 14/76 (18%) Query: 8 GPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRG-GGGPGGGGPGGGS 54 GPP PG P P GGGG G G G PG AG +G G PG G PG Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196 Query: 55 AGGPSQPPGGGG-PGI 69 G S G GG PGI Sbjct: 1197 LPGLSGQKGDGGLPGI 1212 Score = 44.7 bits (104), Expect = 3e-04 Identities = 30/69 (43%), Positives = 32/69 (46%), Gaps = 7/69 (10%) Query: 6 TGGPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPS 59 T GPP GPP G G G GGG PG PG G++G G G G G P Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185 Query: 60 QPPGGGGPG 68 Q PG G PG Sbjct: 1186 Q-PGFGNPG 1193 Score = 43.5 bits (101), Expect = 7e-04 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 11/76 (14%) Query: 8 GPP----PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 GPP PGPP G G G G PPG PG + G G G GP PPG Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Query: 64 -------GGGPGIRKD 72 G PG++ D Sbjct: 909 PLGIPGRSGVPGLKGD 924 Score = 43.5 bits (101), Expect = 7e-04 Identities = 31/72 (43%), Positives = 34/72 (47%), Gaps = 9/72 (12%) Query: 10 PPGPPPPAGGG--GGAGGAGGGPPPGPPG-AGDRGGGGPGG--GGPGG----GSAGGPSQ 60 PPGPP G G G G PPG PG G +G GP G G PG G G P Q Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQ 1295 Query: 61 PPGGGGPGIRKD 72 P G PG++ D Sbjct: 1296 PGLPGLPGLKGD 1307 Score = 42.7 bits (99), Expect = 0.001 Identities = 61/216 (28%), Positives = 78/216 (36%), Gaps = 51/216 (23%) Query: 504 PG-PGGPGPAGPMGPFN----------PGPFN-QGP------------PGAPPHAGGPPP 539 PG PG PGP GP GP PGP +GP PG P H G P P Sbjct: 59 PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP 118 Query: 540 HQYP-----------PQGWGNTYPQWQPPAPHDPS-KAAAAAADPNAAWAAYYSHYYQQP 587 P P G Q P P P K + ++ + Y P Sbjct: 119 QGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP 178 Query: 588 PG--------PVPGPAPAPAAPPAQGEPPQPP--PTGQSDYTKAWEEYYKKIGQQPQQ-- 635 PG +PGP P PP PP PP P + + ++ + G+Q Q Sbjct: 179 PGIQGLPGPTGIPGPI-GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237 Query: 636 PGAPPQ-QDYTKAWEEYYKKQAQVATGG-GPGAPPG 669 PG P Q + + + ++K Q G GP PPG Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273 Score = 42.4 bits (98), Expect = 0.002 Identities = 26/57 (45%), Positives = 27/57 (47%), Gaps = 7/57 (12%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGP 67 PG P P G G G G PPGPPG+ GP GP G GP PPG GP Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGS-----PGPALEGPKGNP--GPQGPPGRPGP 1265 Score = 41.6 bits (96), Expect = 0.003 Identities = 32/75 (42%), Positives = 35/75 (46%), Gaps = 17/75 (22%) Query: 12 GPPPPAGGGGGAG--GAGGGPPPGPPG-AGDRGGGG-------PGGGGPGG-----GSAG 56 G P PAG G G G G PPG PG +G +G GG PG GP G G G Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232 Query: 57 --GPSQPPGGGGPGI 69 GP PPG GP + Sbjct: 1233 VQGPPGPPGSPGPAL 1247 Score = 41.2 bits (95), Expect = 0.003 Identities = 28/62 (45%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGG-PGGGGP--GGGSAGGPSQPPGGGG 66 PG P G G G G PPGP G +G G G PG GP GGG G P P G Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168 Query: 67 PG 68 PG Sbjct: 1169 PG 1170 Score = 41.2 bits (95), Expect = 0.003 Identities = 28/68 (41%), Positives = 31/68 (45%), Gaps = 7/68 (10%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPG----GGSAGGPSQPP 62 P GPP G GG G G PG PG G +G GP G G PG G G P P Sbjct: 1274 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1333 Query: 63 GGGGPGIR 70 G PG++ Sbjct: 1334 VPGFPGMK 1341 Score = 40.8 bits (94), Expect = 0.004 Identities = 28/71 (39%), Positives = 31/71 (43%), Gaps = 12/71 (16%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGP------PGAGDRGGGG----PGGGGPGG--GSAGGP 58 PG P P G G G G PPGP G++G G PG GP G G G P Sbjct: 931 PGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP 990 Query: 59 SQPPGGGGPGI 69 QP G PG+ Sbjct: 991 GQPGLSGQPGL 1001 Score = 40.4 bits (93), Expect = 0.006 Identities = 31/73 (42%), Positives = 32/73 (43%), Gaps = 19/73 (26%) Query: 8 GPPPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGGGGPGG----GGPG-GGSAGGP 58 GPP P PP GA PPGPPG G +G GP G G PG G G P Sbjct: 380 GPPGLPGPP--------GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431 Query: 59 S--QPPGGGGPGI 69 PPG GP I Sbjct: 432 GLPGPPGPAGPHI 444 Score = 40.4 bits (93), Expect = 0.006 Identities = 32/78 (41%), Positives = 33/78 (42%), Gaps = 19/78 (24%) Query: 8 GPPP----GPPPPAGGGGGAGGAGG-GPP----PGPPGAGDRGG--GGPGGGGPGGG--- 53 GPP GPP P G G G G GPP PGPPG + G G PG GP G Sbjct: 386 GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445 Query: 54 -----SAGGPSQPPGGGG 66 GP PPG G Sbjct: 446 PSDEICEPGPPGPPGSPG 463 Score = 40.4 bits (93), Expect = 0.006 Identities = 67/247 (27%), Positives = 76/247 (30%), Gaps = 49/247 (19%) Query: 396 GPPGPPGGPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKAI 450 GPPGPPG PG P G G GPPG G P GL G GG + Sbjct: 1235 GPPGPPGSPG--PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLP-GNGGIKGEKG 1291 Query: 451 NQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEG-PLCPVGPGPGG- 508 N + G P ++G+P + + + G P P GP G Sbjct: 1292 NPGQPGLPGLPGLKGDQGPPG-----LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV 1346 Query: 509 ---------------PGPAGPMGPFNPGPF---NQGPPGAPPHAG--GPPPHQYPPQGWG 548 PGP G GP + GPPG P G G P Q P G Sbjct: 1347 PGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1406 Query: 549 NTYPQWQPPAPHDP--SKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE 606 T P P P A DP P P P P Sbjct: 1407 PTGPPGDPGRNGLPGFDGAGGRKGDPGL------------PGQPGTRGLDGPPGPDGLQG 1454 Query: 607 PPQPPPT 613 PP PP T Sbjct: 1455 PPGPPGT 1461 Score = 40.0 bits (92), Expect = 0.007 Identities = 32/71 (45%), Positives = 33/71 (46%), Gaps = 9/71 (12%) Query: 8 GPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRG-----GGGPG-GGGPG-GGSAGGP 58 GPP GPP P G G G AG PG PG GD G G PG G PG G G P Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680 Query: 59 SQPPGGGGPGI 69 P G PG+ Sbjct: 681 GDPGLPGQPGL 691 Score = 38.9 bits (89), Expect = 0.017 Identities = 29/63 (46%), Positives = 29/63 (46%), Gaps = 7/63 (11%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGG-PGGGSAGGPSQPPG-GG 65 PPG P P G G G G PPG PG G G G PG G PG G PPG G Sbjct: 1259 PPGRPGPTGFQGLPGPEG---PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQG 1315 Query: 66 GPG 68 PG Sbjct: 1316 NPG 1318 Score = 38.1 bits (87), Expect = 0.028 Identities = 31/72 (43%), Positives = 31/72 (43%), Gaps = 7/72 (9%) Query: 3 DYSTGGPP--PGPP--PPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSA 55 D G P PG P P G G G G PGPPG G G GP G G PG Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735 Query: 56 GGPSQPPGGGGP 67 GP PPG GP Sbjct: 736 EGPPGPPGFPGP 747 Score = 38.1 bits (87), Expect = 0.028 Identities = 34/87 (39%), Positives = 35/87 (40%), Gaps = 27/87 (31%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGP----------PPGPPG-------------AGDRG-G 42 G P P PP + G G GA G P PPGPPG GD G Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928 Query: 43 GGPGGGGPGG--GSAGGPSQPPGGGGP 67 G PG GP G GS G P PG GP Sbjct: 929 GQPGLPGPTGEKGSKGEPGL-PGPPGP 954 Score = 37.7 bits (86), Expect = 0.037 Identities = 29/65 (44%), Positives = 29/65 (44%), Gaps = 5/65 (7%) Query: 8 GPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63 GPP PG P G G G G P GPPG R G PG G GG G G P QP Sbjct: 1382 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGL-PGFDGAGGRKGDPGLPGQPGT 1440 Query: 64 GGGPG 68 G G Sbjct: 1441 RGLDG 1445 Score = 37.7 bits (86), Expect = 0.037 Identities = 27/60 (45%), Positives = 27/60 (45%), Gaps = 12/60 (20%) Query: 10 PPGPPPPAGGGG-----GAGGAGGGPP-PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 P GPP G G GAGG G P PG PG RG GP PG GP PPG Sbjct: 1407 PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT--RGLDGP----PGPDGLQGPPGPPG 1460 Score = 37.0 bits (84), Expect = 0.063 Identities = 27/65 (41%), Positives = 28/65 (43%), Gaps = 10/65 (15%) Query: 10 PPGPPPPAGGGGGA----GGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63 PPGPP G G + G AG PG PG G PG GP G G G P P Sbjct: 1361 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLK----GLPGPQGPQGLPGPTGPPGDPGR 1416 Query: 64 GGGPG 68 G PG Sbjct: 1417 NGLPG 1421 Score = 36.6 bits (83), Expect = 0.083 Identities = 29/64 (45%), Positives = 30/64 (46%), Gaps = 15/64 (23%) Query: 6 TGGPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGG--GSAG--GPS 59 TG P P GPP P G G PPGPPG G +G G GP G G G GP Sbjct: 188 TGIPGPIGPPGPPGLMG---------PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP 238 Query: 60 QPPG 63 PPG Sbjct: 239 GPPG 242 Score = 36.6 bits (83), Expect = 0.083 Identities = 27/63 (42%), Positives = 29/63 (46%), Gaps = 6/63 (9%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQP--PGG 64 PG P G G G G PG PGA + G G PG GP G G +G P P PG Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE 1147 Query: 65 GGP 67 GP Sbjct: 1148 PGP 1150 Score = 36.6 bits (83), Expect = 0.083 Identities = 45/170 (26%), Positives = 53/170 (31%), Gaps = 64/170 (37%) Query: 365 GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--PGGRGRGRGQGNWGP 422 GPE ++GPP ++ +GPPG PG PG+ PG +G G GP Sbjct: 1351 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1410 Query: 423 PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQ 482 PG +P G GG GDP Sbjct: 1411 PGDPGRNGLPGFD-----GAGGR---------------------KGDPGL---------- 1434 Query: 483 QIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFN-QGPPGAP 531 PG PG G GP PGP QGPPG P Sbjct: 1435 -----------------------PGQPGTRGLDGP--PGPDGLQGPPGPP 1459 Score = 36.2 bits (82), Expect = 0.11 Identities = 31/78 (39%), Positives = 32/78 (41%), Gaps = 17/78 (21%) Query: 10 PPGPPPPAG------GGGGAGGAGGGP-------PPGPPGAGDRGG--GGPGGGG-PGGG 53 PPG P P+G G G G G P P GP G G G PG G PG Sbjct: 1364 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1423 Query: 54 SAGGPSQPPG-GGGPGIR 70 AGG PG G PG R Sbjct: 1424 GAGGRKGDPGLPGQPGTR 1441 Score = 35.8 bits (81), Expect = 0.14 Identities = 25/60 (41%), Positives = 25/60 (41%), Gaps = 3/60 (5%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPG-GGGPGGGSAGGPSQPPGGGGP 67 PGP P G G G G G PG GG G PG G PG GP P G GP Sbjct: 1396 PGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGP 1455 Score = 35.4 bits (80), Expect = 0.18 Identities = 31/79 (39%), Positives = 31/79 (39%), Gaps = 18/79 (22%) Query: 3 DYSTGGPPP--GPPPPAGGGGGAGGAGGGP-------------PPGPPGA-GDRG-GGGP 45 D GPP GPP P GG G G G P PG PG GD G G P Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324 Query: 46 GGGGPGGGSAG-GPSQPPG 63 G G G GP PPG Sbjct: 325 GRDGEKGQKGDTGPPGPPG 343 Score = 35.0 bits (79), Expect = 0.24 Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 11/71 (15%) Query: 8 GPP--PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGG-PGGGGPGGGSAGG 57 GPP PG P G G G G G PPGP G AG+ G G PG G G + Sbjct: 603 GPPGNPGLPGLPGNIGPMGPPGFG-PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661 Query: 58 PSQPPGGGGPG 68 P +P G PG Sbjct: 662 PGKPGLPGNPG 672 Score = 34.3 bits (77), Expect = 0.41 Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 6/65 (9%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGA----GDRGGGGPGGGGPGG--GSAGGPSQPPGGG 65 G P P G G G +G PG PG GD+G G G G G G P P G Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092 Query: 66 GPGIR 70 PGI+ Sbjct: 1093 NPGIK 1097 Score = 33.9 bits (76), Expect = 0.54 Identities = 29/78 (37%), Positives = 32/78 (41%), Gaps = 18/78 (23%) Query: 11 PGPPPPAGGG--GGAGGAGGGPPPGPPGA----------GDRG----GGGPGGGGPGG-- 52 PGPP P G G G PG PG GD G G PG GP G Sbjct: 949 PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008 Query: 53 GSAGGPSQPPGGGGPGIR 70 G+ G P QP G PG++ Sbjct: 1009 GNPGLPGQPGLIGPPGLK 1026 Score = 33.9 bits (76), Expect = 0.54 Identities = 27/64 (42%), Positives = 29/64 (45%), Gaps = 6/64 (9%) Query: 11 PGPP--PPAGGGGGAGGAGGGPP-PGPPGAGDRGG--GGPG-GGGPGGGSAGGPSQPPGG 64 PGPP P G G GG G P PG PG G G PG G PG + GP+ Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 65 GGPG 68 G PG Sbjct: 1252 GNPG 1255 Score = 33.5 bits (75), Expect = 0.70 Identities = 34/89 (38%), Positives = 35/89 (39%), Gaps = 28/89 (31%) Query: 8 GPP--------PGPPPPAG--------GGGGAGGAGGGPP-PGPPGA----GDRGGGG-- 44 GPP PGPP G G GA G G P PG PGA G +G G Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI 550 Query: 45 ---PGGGGPGG--GSAGGPSQPPGGGGPG 68 PG G G GS G P P G PG Sbjct: 551 LTFPGMKGDKGELGSPGAPGLPGLPGTPG 579 Score = 33.5 bits (75), Expect = 0.70 Identities = 25/66 (37%), Positives = 27/66 (40%), Gaps = 6/66 (9%) Query: 10 PPGPPPPAGGGGGAGGAG-GGPP-----PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 PPG G G G G GPP PG PG+ G G PG S G P P Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081 Query: 64 GGGPGI 69 G PG+ Sbjct: 1082 KGEPGL 1087 Score = 33.1 bits (74), Expect = 0.92 Identities = 28/81 (34%), Positives = 31/81 (38%), Gaps = 21/81 (25%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGG------PGGGGPGG----------- 52 PGP G G +G G PG PG GD+G G PG GP G Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094 Query: 53 ---GSAGGPSQPPGGGGPGIR 70 GS G P P G PG + Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAK 1115 Score = 32.3 bits (72), Expect = 1.6 Identities = 21/58 (36%), Positives = 21/58 (36%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGP 67 P G P G G G G PG PG G G PG GP P G GP Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138 Score = 32.0 bits (71), Expect = 2.0 Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 12/72 (16%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGG-GGPGGGGPGG-------GSAGG 57 PPGP G G G G G PG G++G G PG GP G GS G Sbjct: 906 PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965 Query: 58 PSQPPGGGGPGI 69 +P G PG+ Sbjct: 966 KGEPGLPGIPGV 977 Score = 30.4 bits (67), Expect = 5.9 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 6/65 (9%) Query: 11 PGPPPPAGGGGGAGGAGGGPP--PGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGG 64 PG P G G G + G P PGP G G G PG G G G G P P Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115 Query: 65 GGPGI 69 G PG+ Sbjct: 1116 GQPGL 1120 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 73.2 bits (178), Expect = 8e-13 Identities = 101/355 (28%), Positives = 121/355 (34%), Gaps = 91/355 (25%) Query: 396 GPPGPPGGPGMP-----PGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGE 445 GPPGP G PG+P PG GR +G GPPG GE F++P G Sbjct: 710 GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP----------GPP 759 Query: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG 505 + GA L P GD RG P + + + GP VGP Sbjct: 760 GPPGLPGFKGA-------LGPKGD--------RGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 506 PGGPGPAGPMG------------PFNPGPFNQ----------GPPGAPP-HAGGPPPHQY 542 G PGP GP G P PGP Q G PG P GPP + Sbjct: 805 -GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863 Query: 543 PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPP 602 P G P P +P P KA A+ PPGP PGP P Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG-----PPGP-PGPLGIPGRSG 917 Query: 603 A---------QGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK 653 QG+P P PTG+ K +P PG P D Sbjct: 918 VPGLKGDDGLQGQPGLPGPTGE-----------KGSKGEPGLPGPPGPMD-----PNLLG 961 Query: 654 KQAQVATGGGPGAPPGSQP-DYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQ 707 + + G PG P S P Y + + + PGP GP+ P GQ Sbjct: 962 SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016 Score = 65.9 bits (159), Expect = 1e-10 Identities = 190/754 (25%), Positives = 243/754 (32%), Gaps = 180/754 (23%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69 PGPP P G G G G PG PG G G GP G G+ G P G PG+ Sbjct: 83 PGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142 Query: 70 RKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDS 129 + + + G+ + + +S P G K P + L Sbjct: 143 QGPPGPPGIPGMK-------GEPGSIIMSSLP-----GPKGNPGYPGPPGIQGLPGP-TG 189 Query: 130 ISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPE 189 I +GP PP P G GL +G +N Q G K + G P Sbjct: 190 IPGPIGPPGPPGLMG-------PPGPPGLPGPKGNMGLN-FQGPKGEKGEQGLQ--GPP- 238 Query: 190 RSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVI 249 G P + + K +D +G G PG D G G I P G G Sbjct: 239 ------GPPGQISEQKRPIDVEFQKGDQGLPG---DRGPPGPPG----IRGPPGPPGGEK 285 Query: 250 GKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDP-YKVQQACEMVMDILRERDQ 308 G+ GE Q G + +DG +N P + GDP Y + R+ ++ Sbjct: 286 GEKGE-----QGEPGKRGKPGKDG-ENGQPGIP-GLPGDPGYPGEPG--------RDGEK 330 Query: 309 GGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEM-IKKIQNDAGVRIQFKQDDGTGPE 367 G GD G + +PR G+ IG G + + + + G R Sbjct: 331 GQKGDTGPPGPP-----GLVIPRPGTGITIGEKGNIGLPGLPGEKGER------------ 373 Query: 368 KIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPG----GPGMPPGGRGRGRGQGNWGPP 423 I GPP G PGPPG GP PPG G +G+ GPP Sbjct: 374 GFPGIQGPP-------------------GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414 Query: 424 GGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSP-- 481 G SIP GL G + G + S ++ G P GSP Sbjct: 415 G----ISIPGPP-GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP-----GSPGD 464 Query: 482 -----------QQIDHAKQLIEEKIEGPLCPVGPG-PGGPGPAGPMG-PFNPGPFNQ--- 525 + D I I GP P PG PG PGP G +G P G Q Sbjct: 465 KGLQGEQGVKGDKGDTCFNCIGTGISGP--PGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522 Query: 526 -GPPGAPPHAGGPPPHQYP------------PQGWGNTYPQWQPPAPHDPSKAAAAAADP 572 GP G P G P +P P G+ P AP P D Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582 Query: 573 NAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE--PPQPP-------------PTGQSD 617 PG +PGP P +GE PP P P G Sbjct: 583 L--------------PG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627 Query: 618 YTKAWEEYYKKIGQQPQQPGAP-----PQQDYTKAWEEYYK----KQAQVATGGGPGAPP 668 E+ + + P QPG P P Q T+ + + V G PG P Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP- 686 Query: 669 GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPP 702 QP G PGP GP+ P Sbjct: 687 -GQPGLPGIPGSKGEPGIPGIG-LPGPPGPKGFP 718 Score = 62.8 bits (151), Expect = 1e-09 Identities = 102/353 (28%), Positives = 122/353 (34%), Gaps = 75/353 (21%) Query: 395 SGPPGPPGGPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGEN--- 446 SGPPG PG PG PG G G G GPPG G+ P + G G N Sbjct: 1136 SGPPGNPGLPG-EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194 Query: 447 --VKAINQQTG----AFVEISRQLP-PNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPL 499 + ++ Q G + + LP P G+P F F ++GP Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGF-----------------PGVQGPP 1237 Query: 500 CPVG-PGP------GGPGPAGPMG-PFNPGPFNQGPPGAPPHAG-----GPPPHQYPPQG 546 P G PGP G PGP GP G P PGP +GPPG P + G G P P Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGLPGP--EGPPGLPGNGGIKGEKGNPGQPGLPGL 1295 Query: 547 WGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE 606 G Q P +P + + + P VPG A P P Sbjct: 1296 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA-GPEGEPGLIG 1354 Query: 607 PPQPP----PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG 662 PP PP P+GQS K + I QP G P Q Q G Sbjct: 1355 PPGPPGLPGPSGQSIIIKG-DAGPPGIPGQPGLKGLPGPQG----------PQGLPGPTG 1403 Query: 663 GPGAP-PGSQPDYSAAWAEYYRQQAAYYGQ--------TPGPGGPQPPPTQQG 706 PG P P + A + GQ PGP G Q PP G Sbjct: 1404 PPGDPGRNGLPGFDGAGGR--KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454 Score = 62.4 bits (150), Expect = 1e-09 Identities = 205/819 (25%), Positives = 262/819 (31%), Gaps = 228/819 (27%) Query: 10 PPGPPPPAGGGGGAGGAGGGP-----------PPGPPGA--------------------G 38 PPGPP G G G GP PPGPPG G Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 39 DRGGGGPGG-----GGPGG--GSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGD 91 DRG GP G G PGG G G +P G PG K G + Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG------------------KDGEN 306 Query: 92 AATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRV 151 + D G+ G+ + DG++ + G G + P P T +T + Sbjct: 307 GQPGIPGLPGDPGYPGEPGR--DGEKGQKGDTGPPGPP-----GLVIPRPGTGITIGEKG 359 Query: 152 PDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDI 211 G+ GL +G IQ G G P +V P + Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLP--------GPPGAAVMGPPGPPGFPGERGQ---- 407 Query: 212 VSRGRGGPPGQFHDNANG--GQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMIL 269 +G GPPG G GQ G + P G AG I E + Sbjct: 408 --KGDEGPPGISIPGPPGLDGQPGA-PGLPGPPGPAGPHIPPSDEICEPGPP-------- 456 Query: 270 IQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR-IGGGIDVP 328 G + DK L + +QG GD+ + IG GI P Sbjct: 457 ---GPPGSPGDKGL---------------------QGEQGVKGDKGDTCFNCIGTGISGP 492 Query: 329 VPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDR--CEHAARII 386 + + + G G + G + + Q TGP+ + I G P + Sbjct: 493 PGQPGLPGLPGPPGSL-----GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEP 547 Query: 387 NDLL-------QSLRSGPPGPPGGPGMP-----------PGGRGRGRG---QGNWGPPGG 425 D+L G PG PG PG+P PG +G G +G GPPG Sbjct: 548 GDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN 607 Query: 426 EMTFSIPTH----------KCGLVIGRGGENVKAINQQTGAFVEISRQLP-PNGDPNFKL 474 +P + G V +G + V Q G +P P GDP + Sbjct: 608 PGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG--------IPGPKGDPG-QT 658 Query: 475 FIIRGSPQQIDHAKQLIEEKIEG-PLCPVGPG-PGGPGPAGPMG------PFNPGPFN-- 524 G P + + + + G P P PG PG PG G G P PGP Sbjct: 659 ITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFP 718 Query: 525 --QGPPGAPPHAG-----GPP-PHQYP-PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAA 575 GPPGAP G GPP P +P P+G P + P P P A Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG----EPGFALPGPPGPPGLPGF----KGA 770 Query: 576 WAAYYSHYYQQPPGP--------VPGP--------APAPAAPP------AQGEPPQPP-- 611 + PPGP +PGP P P PP QG PP PP Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG-PPGPPGI 829 Query: 612 --PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPG 669 P GQ I + PG PP D E + + GP PPG Sbjct: 830 PGPIGQPG--------LHGIPGEKGDPG-PPGLDVPGPPGE--RGSPGIPGAPGPIGPPG 878 Query: 670 SQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQG 706 S A A + G PGP GP P + G Sbjct: 879 SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917 Score = 59.7 bits (143), Expect = 9e-09 Identities = 176/686 (25%), Positives = 216/686 (31%), Gaps = 172/686 (25%) Query: 10 PPGPPPPAGGGGGAG--------GAGGGPP-PGPPGAGDRGGGGPGG-----GGPGGGSA 55 PPGPP G G G G G P PGPPG +G GP G G PG Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGI--QGLPGPTGIPGPIGPPGPPGL 202 Query: 56 GGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDG 115 GP PPG GP K Q + + G G G Q+ + Sbjct: 203 MGPPGPPGLPGP---KGNMGLNFQGPKGEKGEQGLQ------------GPPGPPGQISEQ 247 Query: 116 DQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSG 175 +P + + GP PP R P G G G GEQ ++ Sbjct: 248 KRPIDVEFQKGDQGLPGDRGPPGPP-------GIRGPPGPPGGEKGEKGEQGEPGKRGKP 300 Query: 176 CK--VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNG 233 K P GLP G P GR G GQ D G G Sbjct: 301 GKDGENGQPGIPGLP-GDPGYPGEP----------------GRDGEKGQKGDTGPPGPPG 343 Query: 234 TVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKV 292 ++IP G+ IG+ G G+ + + G + + P + G P Sbjct: 344 ----LVIPRPGTGITIGEKG--------NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391 Query: 293 QQACEMVMDILRERDQGGFGDRNEYGSRIGG--GID-------VPVPRHSVGVVIGRSGE 343 ER Q GD G I G G+D +P P G I S E Sbjct: 392 VMGPPGPPGFPGERGQK--GDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 344 MI-------------KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLL 390 + K +Q + GV K D G D C + + Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGV----KGDKG-------------DTCFNC-------I 485 Query: 391 QSLRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVK 448 + SGPPG PG PG+ PPG G +G G G +P G+ G Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP----GIPGAPGAPGFP 541 Query: 449 AINQQTGAFVEI------SRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE------ 496 + G + +L G P L + G+P Q D L K E Sbjct: 542 GSKGEPGDILTFPGMKGDKGELGSPGAPG--LPGLPGTPGQ-DGLPGLPGPKGEPGGITF 598 Query: 497 ----GPLCPVGPG-PGGPGPAGPMGPFN---PGPF----------NQGPPGAPPHAGGP- 537 GP P PG PG PG GPMGP PGP N G PG P G P Sbjct: 599 KGERGP--PGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656 Query: 538 -----PPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGP-- 590 P P G P P P + + PPGP Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716 Query: 591 ---VPGPAPAPAAPPAQG--EPPQPP 611 +PGP AP P G PP PP Sbjct: 717 FPGIPGPPGAPGTPGRIGLEGPPGPP 742 Score = 58.5 bits (140), Expect = 2e-08 Identities = 98/353 (27%), Positives = 114/353 (32%), Gaps = 88/353 (24%) Query: 396 GPPGPPGGPGMPPGGRGRGRGQ-GNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKA 449 GPPGP G PG+P GQ G GPPG G+M F P G Sbjct: 1003 GPPGPKGNPGLP--------GQPGLIGPPGLKGTIGDMGFPGPQGV------EGPPGPSG 1048 Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDH-------AKQLIEEKIEGPLCPV 502 + Q G+ + Q GDP + G P I+ + P P Sbjct: 1049 VPGQPGS-PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG 1107 Query: 503 GPG-------------PGGPGPAGPMG----PFNPG-PFNQGPPGAPPHAG--GPPPHQY 542 PG PG PGP GP G P NPG P GP G H G GPP + Sbjct: 1108 LPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKG 1167 Query: 543 PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPP 602 P G P Q P P +P S Q+ G +PG P P Sbjct: 1168 KPGQDGIPGPAGQKGEPGQP-----GFGNPGPPGLPGLSG--QKGDGGLPGIPGNPGLPG 1220 Query: 603 AQGEP-------PQPPPTGQSDYTKAWEEYYKKIGQQ--PQQPGAPPQQDYTKAWEEYYK 653 +GEP Q PP A E G Q P +PG P Sbjct: 1221 PKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLP-------------- 1266 Query: 654 KQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQG 706 GP PPG + + Q G PG G Q PP QG Sbjct: 1267 ---------GPEGPPGLPGNGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQG 1309 Score = 52.4 bits (124), Expect = 1e-06 Identities = 89/340 (26%), Positives = 105/340 (30%), Gaps = 97/340 (28%) Query: 396 GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447 GP GPPG PG+P PG +G G GPPG IP GR G V Sbjct: 872 GPIGPPGSPGLPGKAGASGFPGTKGE---MGMMGPPGPPGPLGIP--------GRSG--V 918 Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP--G 505 + G ++G P + GP G Sbjct: 919 PGLKGDDG---------------------LQGQP------------GLPGPTGEKGSKGE 945 Query: 506 PGGPGPAGPMGPFNPGPFNQ-GPPGAP--PHAGGPPPHQYPPQGWGNTYPQWQP--PAPH 560 PG PGP GPM P G + G PG P P GP +Q P G QP P P Sbjct: 946 PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005 Query: 561 DPSKAAAAAADPNAAWAAYYSHYYQQP--PGP-----VPGPAPAPAAPPAQGEPPQPPPT 613 P P PGP PGP+ P P + G P Q Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065 Query: 614 GQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAP--PGS- 670 G + +P PG P + V G PG P PG+ Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGI----------KGSVGDPGLPGLPGTPGAK 1115 Query: 671 -QPDYSAAWAEYYRQQAAYYGQTPGPGGPQ---PPPTQQG 706 QP + TPGP GP+ PP G Sbjct: 1116 GQPGLPG------------FPGTPGPPGPKGISGPPGNPG 1143 Score = 47.0 bits (110), Expect = 6e-05 Identities = 95/358 (26%), Positives = 114/358 (31%), Gaps = 72/358 (20%) Query: 365 GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGP-- 422 GP I + G P ++ S GP G PG PG PPG +G G GP Sbjct: 147 GPPGIPGMKGEP----------GSIIMSSLPGPKGNPGYPG-PPGIQGLPGPTGIPGPIG 195 Query: 423 PGGEMTFSIPTHKCGLVIGRG--GENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS 480 P G P GL +G G N + + G E Q PP G Sbjct: 196 PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG---EQGLQGPP------------GP 240 Query: 481 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH 540 P QI K+ I+ + + + G PGP G GP PGP G G G P Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP--PGP-PGGEKGEKGEQGEPGKR 297 Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA 600 P + N P P P DP D PPGP P P Sbjct: 298 GKPGKDGENGQP-GIPGLPGDPGYPGEPGRDGEKGQKGDTG-----PPGPPGLVIPRPGT 351 Query: 601 PPAQGE------PPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK- 653 GE P P G E + I P PG P + Sbjct: 352 GITIGEKGNIGLPGLPGEKG--------ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403 Query: 654 KQAQVATGGGPG----APPG--SQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQ 705 ++ Q G PG PPG QP A PGP GP PP+ + Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPG------------APGLPGPPGPAGPHIPPSDE 449 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/63 (44%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69 PGPP P G G G G PPG G GD G GP G G +G P QP G PG Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061 Query: 70 RKD 72 + D Sbjct: 1062 KGD 1064 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/76 (43%), Positives = 34/76 (44%), Gaps = 14/76 (18%) Query: 8 GPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRG-GGGPGGGGPGGGS 54 GPP PG P P GGGG G G G PG AG +G G PG G PG Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196 Query: 55 AGGPSQPPGGGG-PGI 69 G S G GG PGI Sbjct: 1197 LPGLSGQKGDGGLPGI 1212 Score = 44.7 bits (104), Expect = 3e-04 Identities = 30/69 (43%), Positives = 32/69 (46%), Gaps = 7/69 (10%) Query: 6 TGGPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPS 59 T GPP GPP G G G GGG PG PG G++G G G G G P Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185 Query: 60 QPPGGGGPG 68 Q PG G PG Sbjct: 1186 Q-PGFGNPG 1193 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/64 (43%), Positives = 30/64 (46%), Gaps = 8/64 (12%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA------GDRGGGGPGG--GGPGGGSAGGPSQPP 62 PG P P G G G G PPGPPG+ G +G GP G G PG GP P Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLP 1275 Query: 63 GGGG 66 G GG Sbjct: 1276 GNGG 1279 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/66 (42%), Positives = 30/66 (45%), Gaps = 3/66 (4%) Query: 10 PPGPPPPAGGG--GGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPSQPPGGGG 66 PPGPP G G G G PPG PG G G G G G G G P QP G Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1295 Query: 67 PGIRKD 72 PG++ D Sbjct: 1296 PGLKGD 1301 Score = 43.5 bits (101), Expect = 7e-04 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 11/76 (14%) Query: 8 GPP----PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 GPP PGPP G G G G PPG PG + G G G GP PPG Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Query: 64 -------GGGPGIRKD 72 G PG++ D Sbjct: 909 PLGIPGRSGVPGLKGD 924 Score = 43.5 bits (101), Expect = 7e-04 Identities = 70/235 (29%), Positives = 80/235 (34%), Gaps = 56/235 (23%) Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 R G PGP G PG+P G +G +GN G PG +P GL +G + + Sbjct: 1262 RPGLPGPEGPPGLPGNGGIKGE-KGNPGQPG------LP----GLPGLKGDQGPPGLQGN 1310 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPL-CPVGPGP-GGPGP 511 G GDP L + G P ++GP P GP G PG Sbjct: 1311 PGR----PGLNGMKGDPG--LPGVPGFP------------GMKGPSGVPGSAGPEGEPGL 1352 Query: 512 AGPMGPFN-PGPFNQ--------GPPGAPPHAG--GPPPHQYPPQGWGNTYPQWQPPAPH 560 GP GP PGP Q GPPG P G G P Q P G T P P Sbjct: 1353 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1412 Query: 561 DP--SKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPT 613 P A DP P P P P PP PP T Sbjct: 1413 LPGFDGAGGRKGDPGL------------PGQPGTRGLDGPPGPDGLQGPPGPPGT 1455 Score = 42.7 bits (99), Expect = 0.001 Identities = 61/216 (28%), Positives = 78/216 (36%), Gaps = 51/216 (23%) Query: 504 PG-PGGPGPAGPMGPFN----------PGPFN-QGP------------PGAPPHAGGPPP 539 PG PG PGP GP GP PGP +GP PG P H G P P Sbjct: 59 PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP 118 Query: 540 HQYP-----------PQGWGNTYPQWQPPAPHDPS-KAAAAAADPNAAWAAYYSHYYQQP 587 P P G Q P P P K + ++ + Y P Sbjct: 119 QGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP 178 Query: 588 PG--------PVPGPAPAPAAPPAQGEPPQPP--PTGQSDYTKAWEEYYKKIGQQPQQ-- 635 PG +PGP P PP PP PP P + + ++ + G+Q Q Sbjct: 179 PGIQGLPGPTGIPGPI-GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237 Query: 636 PGAPPQ-QDYTKAWEEYYKKQAQVATGG-GPGAPPG 669 PG P Q + + + ++K Q G GP PPG Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273 Score = 41.6 bits (96), Expect = 0.003 Identities = 32/75 (42%), Positives = 35/75 (46%), Gaps = 17/75 (22%) Query: 12 GPPPPAGGGGGAG--GAGGGPPPGPPG-AGDRGGGG-------PGGGGPGG-----GSAG 56 G P PAG G G G G PPG PG +G +G GG PG GP G G G Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232 Query: 57 --GPSQPPGGGGPGI 69 GP PPG GP + Sbjct: 1233 VQGPPGPPGSPGPAL 1247 Score = 41.6 bits (96), Expect = 0.003 Identities = 33/78 (42%), Positives = 36/78 (46%), Gaps = 15/78 (19%) Query: 8 GPP-----PGPPPPAG--GGGGAGGAGGGP-PPGPPG-AGDRGGGGPGG--GGPG----G 52 GPP PGP P G G GG G G P PG PG G +G GP G G PG Sbjct: 1258 GPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1317 Query: 53 GSAGGPSQPPGGGGPGIR 70 G G P P G PG++ Sbjct: 1318 GMKGDPGLPGVPGFPGMK 1335 Score = 41.2 bits (95), Expect = 0.003 Identities = 28/62 (45%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGG-PGGGGP--GGGSAGGPSQPPGGGG 66 PG P G G G G PPGP G +G G G PG GP GGG G P P G Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168 Query: 67 PG 68 PG Sbjct: 1169 PG 1170 Score = 40.8 bits (94), Expect = 0.004 Identities = 28/71 (39%), Positives = 31/71 (43%), Gaps = 12/71 (16%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGP------PGAGDRGGGG----PGGGGPGG--GSAGGP 58 PG P P G G G G PPGP G++G G PG GP G G G P Sbjct: 931 PGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP 990 Query: 59 SQPPGGGGPGI 69 QP G PG+ Sbjct: 991 GQPGLSGQPGL 1001 Score = 40.4 bits (93), Expect = 0.006 Identities = 31/73 (42%), Positives = 32/73 (43%), Gaps = 19/73 (26%) Query: 8 GPPPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGGGGPGG----GGPG-GGSAGGP 58 GPP P PP GA PPGPPG G +G GP G G PG G G P Sbjct: 380 GPPGLPGPP--------GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431 Query: 59 S--QPPGGGGPGI 69 PPG GP I Sbjct: 432 GLPGPPGPAGPHI 444 Score = 40.4 bits (93), Expect = 0.006 Identities = 32/78 (41%), Positives = 33/78 (42%), Gaps = 19/78 (24%) Query: 8 GPPP----GPPPPAGGGGGAGGAGG-GPP----PGPPGAGDRGG--GGPGGGGPGGG--- 53 GPP GPP P G G G G GPP PGPPG + G G PG GP G Sbjct: 386 GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445 Query: 54 -----SAGGPSQPPGGGG 66 GP PPG G Sbjct: 446 PSDEICEPGPPGPPGSPG 463 Score = 40.0 bits (92), Expect = 0.007 Identities = 32/71 (45%), Positives = 33/71 (46%), Gaps = 9/71 (12%) Query: 8 GPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRG-----GGGPG-GGGPG-GGSAGGP 58 GPP GPP P G G G AG PG PG GD G G PG G PG G G P Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680 Query: 59 SQPPGGGGPGI 69 P G PG+ Sbjct: 681 GDPGLPGQPGL 691 Score = 38.1 bits (87), Expect = 0.028 Identities = 31/72 (43%), Positives = 31/72 (43%), Gaps = 7/72 (9%) Query: 3 DYSTGGPP--PGPP--PPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSA 55 D G P PG P P G G G G PGPPG G G GP G G PG Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735 Query: 56 GGPSQPPGGGGP 67 GP PPG GP Sbjct: 736 EGPPGPPGFPGP 747 Score = 38.1 bits (87), Expect = 0.028 Identities = 34/87 (39%), Positives = 35/87 (40%), Gaps = 27/87 (31%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGP----------PPGPPG-------------AGDRG-G 42 G P P PP + G G GA G P PPGPPG GD G Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928 Query: 43 GGPGGGGPGG--GSAGGPSQPPGGGGP 67 G PG GP G GS G P PG GP Sbjct: 929 GQPGLPGPTGEKGSKGEPGL-PGPPGP 954 Score = 37.7 bits (86), Expect = 0.037 Identities = 29/65 (44%), Positives = 29/65 (44%), Gaps = 5/65 (7%) Query: 8 GPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63 GPP PG P G G G G P GPPG R G PG G GG G G P QP Sbjct: 1376 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGL-PGFDGAGGRKGDPGLPGQPGT 1434 Query: 64 GGGPG 68 G G Sbjct: 1435 RGLDG 1439 Score = 37.7 bits (86), Expect = 0.037 Identities = 27/60 (45%), Positives = 27/60 (45%), Gaps = 12/60 (20%) Query: 10 PPGPPPPAGGGG-----GAGGAGGGPP-PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 P GPP G G GAGG G P PG PG RG GP PG GP PPG Sbjct: 1401 PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT--RGLDGP----PGPDGLQGPPGPPG 1454 Score = 37.0 bits (84), Expect = 0.063 Identities = 27/65 (41%), Positives = 28/65 (43%), Gaps = 10/65 (15%) Query: 10 PPGPPPPAGGGGGA----GGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63 PPGPP G G + G AG PG PG G PG GP G G G P P Sbjct: 1355 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLK----GLPGPQGPQGLPGPTGPPGDPGR 1410 Query: 64 GGGPG 68 G PG Sbjct: 1411 NGLPG 1415 Score = 36.6 bits (83), Expect = 0.083 Identities = 29/64 (45%), Positives = 30/64 (46%), Gaps = 15/64 (23%) Query: 6 TGGPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGG--GSAG--GPS 59 TG P P GPP P G G PPGPPG G +G G GP G G G GP Sbjct: 188 TGIPGPIGPPGPPGLMG---------PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP 238 Query: 60 QPPG 63 PPG Sbjct: 239 GPPG 242 Score = 36.6 bits (83), Expect = 0.083 Identities = 27/63 (42%), Positives = 29/63 (46%), Gaps = 6/63 (9%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQP--PGG 64 PG P G G G G PG PGA + G G PG GP G G +G P P PG Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE 1147 Query: 65 GGP 67 GP Sbjct: 1148 PGP 1150 Score = 36.6 bits (83), Expect = 0.083 Identities = 28/62 (45%), Positives = 28/62 (45%), Gaps = 7/62 (11%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGG-PGGGSAGGPSQPPG-GGG 66 PGP P G G G G PPG PG G G G PG G PG G PPG G Sbjct: 1254 PGPQGPPGRPGLPGPEG---PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN 1310 Query: 67 PG 68 PG Sbjct: 1311 PG 1312 Score = 36.6 bits (83), Expect = 0.083 Identities = 45/170 (26%), Positives = 53/170 (31%), Gaps = 64/170 (37%) Query: 365 GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--PGGRGRGRGQGNWGP 422 GPE ++GPP ++ +GPPG PG PG+ PG +G G GP Sbjct: 1345 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1404 Query: 423 PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQ 482 PG +P G GG GDP Sbjct: 1405 PGDPGRNGLPGFD-----GAGGR---------------------KGDPGL---------- 1428 Query: 483 QIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFN-QGPPGAP 531 PG PG G GP PGP QGPPG P Sbjct: 1429 -----------------------PGQPGTRGLDGP--PGPDGLQGPPGPP 1453 Score = 36.2 bits (82), Expect = 0.11 Identities = 31/78 (39%), Positives = 32/78 (41%), Gaps = 17/78 (21%) Query: 10 PPGPPPPAG------GGGGAGGAGGGP-------PPGPPGAGDRGG--GGPGGGG-PGGG 53 PPG P P+G G G G G P P GP G G G PG G PG Sbjct: 1358 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1417 Query: 54 SAGGPSQPPG-GGGPGIR 70 AGG PG G PG R Sbjct: 1418 GAGGRKGDPGLPGQPGTR 1435 Score = 35.8 bits (81), Expect = 0.14 Identities = 23/58 (39%), Positives = 23/58 (39%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGP 67 P GP G G G G PG GAG R G G PG GP P G GP Sbjct: 1392 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGP 1449 Score = 35.4 bits (80), Expect = 0.18 Identities = 31/79 (39%), Positives = 31/79 (39%), Gaps = 18/79 (22%) Query: 3 DYSTGGPPP--GPPPPAGGGGGAGGAGGGP-------------PPGPPGA-GDRG-GGGP 45 D GPP GPP P GG G G G P PG PG GD G G P Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324 Query: 46 GGGGPGGGSAG-GPSQPPG 63 G G G GP PPG Sbjct: 325 GRDGEKGQKGDTGPPGPPG 343 Score = 35.0 bits (79), Expect = 0.24 Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 11/71 (15%) Query: 8 GPP--PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGG-PGGGGPGGGSAGG 57 GPP PG P G G G G G PPGP G AG+ G G PG G G + Sbjct: 603 GPPGNPGLPGLPGNIGPMGPPGFG-PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661 Query: 58 PSQPPGGGGPG 68 P +P G PG Sbjct: 662 PGKPGLPGNPG 672 Score = 34.3 bits (77), Expect = 0.41 Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 6/65 (9%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGA----GDRGGGGPGGGGPGG--GSAGGPSQPPGGG 65 G P P G G G +G PG PG GD+G G G G G G P P G Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092 Query: 66 GPGIR 70 PGI+ Sbjct: 1093 NPGIK 1097 Score = 33.9 bits (76), Expect = 0.54 Identities = 29/78 (37%), Positives = 32/78 (41%), Gaps = 18/78 (23%) Query: 11 PGPPPPAGGG--GGAGGAGGGPPPGPPGA----------GDRG----GGGPGGGGPGG-- 52 PGPP P G G G PG PG GD G G PG GP G Sbjct: 949 PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008 Query: 53 GSAGGPSQPPGGGGPGIR 70 G+ G P QP G PG++ Sbjct: 1009 GNPGLPGQPGLIGPPGLK 1026 Score = 33.9 bits (76), Expect = 0.54 Identities = 27/64 (42%), Positives = 29/64 (45%), Gaps = 6/64 (9%) Query: 11 PGPP--PPAGGGGGAGGAGGGPP-PGPPGAGDRGG--GGPG-GGGPGGGSAGGPSQPPGG 64 PGPP P G G GG G P PG PG G G PG G PG + GP+ Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 65 GGPG 68 G PG Sbjct: 1252 GNPG 1255 Score = 33.5 bits (75), Expect = 0.70 Identities = 34/89 (38%), Positives = 35/89 (39%), Gaps = 28/89 (31%) Query: 8 GPP--------PGPPPPAG--------GGGGAGGAGGGPP-PGPPGA----GDRGGGG-- 44 GPP PGPP G G GA G G P PG PGA G +G G Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI 550 Query: 45 ---PGGGGPGG--GSAGGPSQPPGGGGPG 68 PG G G GS G P P G PG Sbjct: 551 LTFPGMKGDKGELGSPGAPGLPGLPGTPG 579 Score = 33.5 bits (75), Expect = 0.70 Identities = 25/66 (37%), Positives = 27/66 (40%), Gaps = 6/66 (9%) Query: 10 PPGPPPPAGGGGGAGGAG-GGPP-----PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 PPG G G G G GPP PG PG+ G G PG S G P P Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081 Query: 64 GGGPGI 69 G PG+ Sbjct: 1082 KGEPGL 1087 Score = 33.1 bits (74), Expect = 0.92 Identities = 28/81 (34%), Positives = 31/81 (38%), Gaps = 21/81 (25%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGG------PGGGGPGG----------- 52 PGP G G +G G PG PG GD+G G PG GP G Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094 Query: 53 ---GSAGGPSQPPGGGGPGIR 70 GS G P P G PG + Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAK 1115 Score = 32.3 bits (72), Expect = 1.6 Identities = 21/58 (36%), Positives = 21/58 (36%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGP 67 P G P G G G G PG PG G G PG GP P G GP Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138 Score = 32.0 bits (71), Expect = 2.0 Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 12/72 (16%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGG-GGPGGGGPGG-------GSAGG 57 PPGP G G G G G PG G++G G PG GP G GS G Sbjct: 906 PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965 Query: 58 PSQPPGGGGPGI 69 +P G PG+ Sbjct: 966 KGEPGLPGIPGV 977 Score = 30.4 bits (67), Expect = 5.9 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 6/65 (9%) Query: 11 PGPPPPAGGGGGAGGAGGGPP--PGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGG 64 PG P G G G + G P PGP G G G PG G G G G P P Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115 Query: 65 GGPGI 69 G PG+ Sbjct: 1116 GQPGL 1120 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 73.2 bits (178), Expect = 8e-13 Identities = 101/355 (28%), Positives = 121/355 (34%), Gaps = 91/355 (25%) Query: 396 GPPGPPGGPGMP-----PGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGE 445 GPPGP G PG+P PG GR +G GPPG GE F++P G Sbjct: 710 GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP----------GPP 759 Query: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG 505 + GA L P GD RG P + + + GP VGP Sbjct: 760 GPPGLPGFKGA-------LGPKGD--------RGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 506 PGGPGPAGPMG------------PFNPGPFNQ----------GPPGAPP-HAGGPPPHQY 542 G PGP GP G P PGP Q G PG P GPP + Sbjct: 805 -GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863 Query: 543 PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPP 602 P G P P +P P KA A+ PPGP PGP P Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG-----PPGP-PGPLGIPGRSG 917 Query: 603 A---------QGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK 653 QG+P P PTG+ K +P PG P D Sbjct: 918 VPGLKGDDGLQGQPGLPGPTGE-----------KGSKGEPGLPGPPGPMD-----PNLLG 961 Query: 654 KQAQVATGGGPGAPPGSQP-DYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQ 707 + + G PG P S P Y + + + PGP GP+ P GQ Sbjct: 962 SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016 Score = 65.9 bits (159), Expect = 1e-10 Identities = 190/754 (25%), Positives = 243/754 (32%), Gaps = 180/754 (23%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69 PGPP P G G G G PG PG G G GP G G+ G P G PG+ Sbjct: 83 PGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142 Query: 70 RKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDS 129 + + + G+ + + +S P G K P + L Sbjct: 143 QGPPGPPGIPGMK-------GEPGSIIMSSLP-----GPKGNPGYPGPPGIQGLPGP-TG 189 Query: 130 ISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPE 189 I +GP PP P G GL +G +N Q G K + G P Sbjct: 190 IPGPIGPPGPPGLMG-------PPGPPGLPGPKGNMGLN-FQGPKGEKGEQGLQ--GPP- 238 Query: 190 RSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVI 249 G P + + K +D +G G PG D G G I P G G Sbjct: 239 ------GPPGQISEQKRPIDVEFQKGDQGLPG---DRGPPGPPG----IRGPPGPPGGEK 285 Query: 250 GKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDP-YKVQQACEMVMDILRERDQ 308 G+ GE Q G + +DG +N P + GDP Y + R+ ++ Sbjct: 286 GEKGE-----QGEPGKRGKPGKDG-ENGQPGIP-GLPGDPGYPGEPG--------RDGEK 330 Query: 309 GGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEM-IKKIQNDAGVRIQFKQDDGTGPE 367 G GD G + +PR G+ IG G + + + + G R Sbjct: 331 GQKGDTGPPGPP-----GLVIPRPGTGITIGEKGNIGLPGLPGEKGER------------ 373 Query: 368 KIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPG----GPGMPPGGRGRGRGQGNWGPP 423 I GPP G PGPPG GP PPG G +G+ GPP Sbjct: 374 GFPGIQGPP-------------------GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414 Query: 424 GGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSP-- 481 G SIP GL G + G + S ++ G P GSP Sbjct: 415 G----ISIPGPP-GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP-----GSPGD 464 Query: 482 -----------QQIDHAKQLIEEKIEGPLCPVGPG-PGGPGPAGPMG-PFNPGPFNQ--- 525 + D I I GP P PG PG PGP G +G P G Q Sbjct: 465 KGLQGEQGVKGDKGDTCFNCIGTGISGP--PGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522 Query: 526 -GPPGAPPHAGGPPPHQYP------------PQGWGNTYPQWQPPAPHDPSKAAAAAADP 572 GP G P G P +P P G+ P AP P D Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582 Query: 573 NAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE--PPQPP-------------PTGQSD 617 PG +PGP P +GE PP P P G Sbjct: 583 L--------------PG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627 Query: 618 YTKAWEEYYKKIGQQPQQPGAP-----PQQDYTKAWEEYYK----KQAQVATGGGPGAPP 668 E+ + + P QPG P P Q T+ + + V G PG P Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP- 686 Query: 669 GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPP 702 QP G PGP GP+ P Sbjct: 687 -GQPGLPGIPGSKGEPGIPGIG-LPGPPGPKGFP 718 Score = 62.4 bits (150), Expect = 1e-09 Identities = 205/819 (25%), Positives = 262/819 (31%), Gaps = 228/819 (27%) Query: 10 PPGPPPPAGGGGGAGGAGGGP-----------PPGPPGA--------------------G 38 PPGPP G G G GP PPGPPG G Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 39 DRGGGGPGG-----GGPGG--GSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGD 91 DRG GP G G PGG G G +P G PG K G + Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG------------------KDGEN 306 Query: 92 AATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRV 151 + D G+ G+ + DG++ + G G + P P T +T + Sbjct: 307 GQPGIPGLPGDPGYPGEPGR--DGEKGQKGDTGPPGPP-----GLVIPRPGTGITIGEKG 359 Query: 152 PDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDI 211 G+ GL +G IQ G G P +V P + Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLP--------GPPGAAVMGPPGPPGFPGERGQ---- 407 Query: 212 VSRGRGGPPGQFHDNANG--GQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMIL 269 +G GPPG G GQ G + P G AG I E + Sbjct: 408 --KGDEGPPGISIPGPPGLDGQPGA-PGLPGPPGPAGPHIPPSDEICEPGPP-------- 456 Query: 270 IQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR-IGGGIDVP 328 G + DK L + +QG GD+ + IG GI P Sbjct: 457 ---GPPGSPGDKGL---------------------QGEQGVKGDKGDTCFNCIGTGISGP 492 Query: 329 VPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDR--CEHAARII 386 + + + G G + G + + Q TGP+ + I G P + Sbjct: 493 PGQPGLPGLPGPPGSL-----GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEP 547 Query: 387 NDLL-------QSLRSGPPGPPGGPGMP-----------PGGRGRGRG---QGNWGPPGG 425 D+L G PG PG PG+P PG +G G +G GPPG Sbjct: 548 GDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN 607 Query: 426 EMTFSIPTH----------KCGLVIGRGGENVKAINQQTGAFVEISRQLP-PNGDPNFKL 474 +P + G V +G + V Q G +P P GDP + Sbjct: 608 PGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG--------IPGPKGDPG-QT 658 Query: 475 FIIRGSPQQIDHAKQLIEEKIEG-PLCPVGPG-PGGPGPAGPMG------PFNPGPFN-- 524 G P + + + + G P P PG PG PG G G P PGP Sbjct: 659 ITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFP 718 Query: 525 --QGPPGAPPHAG-----GPP-PHQYP-PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAA 575 GPPGAP G GPP P +P P+G P + P P P A Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG----EPGFALPGPPGPPGLPGF----KGA 770 Query: 576 WAAYYSHYYQQPPGP--------VPGP--------APAPAAPP------AQGEPPQPP-- 611 + PPGP +PGP P P PP QG PP PP Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG-PPGPPGI 829 Query: 612 --PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPG 669 P GQ I + PG PP D E + + GP PPG Sbjct: 830 PGPIGQPG--------LHGIPGEKGDPG-PPGLDVPGPPGE--RGSPGIPGAPGPIGPPG 878 Query: 670 SQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQG 706 S A A + G PGP GP P + G Sbjct: 879 SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917 Score = 59.7 bits (143), Expect = 9e-09 Identities = 176/686 (25%), Positives = 216/686 (31%), Gaps = 172/686 (25%) Query: 10 PPGPPPPAGGGGGAG--------GAGGGPP-PGPPGAGDRGGGGPGG-----GGPGGGSA 55 PPGPP G G G G G P PGPPG +G GP G G PG Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGI--QGLPGPTGIPGPIGPPGPPGL 202 Query: 56 GGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDG 115 GP PPG GP K Q + + G G G Q+ + Sbjct: 203 MGPPGPPGLPGP---KGNMGLNFQGPKGEKGEQGLQ------------GPPGPPGQISEQ 247 Query: 116 DQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSG 175 +P + + GP PP R P G G G GEQ ++ Sbjct: 248 KRPIDVEFQKGDQGLPGDRGPPGPP-------GIRGPPGPPGGEKGEKGEQGEPGKRGKP 300 Query: 176 CK--VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNG 233 K P GLP G P GR G GQ D G G Sbjct: 301 GKDGENGQPGIPGLP-GDPGYPGEP----------------GRDGEKGQKGDTGPPGPPG 343 Query: 234 TVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKV 292 ++IP G+ IG+ G G+ + + G + + P + G P Sbjct: 344 ----LVIPRPGTGITIGEKG--------NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391 Query: 293 QQACEMVMDILRERDQGGFGDRNEYGSRIGG--GID-------VPVPRHSVGVVIGRSGE 343 ER Q GD G I G G+D +P P G I S E Sbjct: 392 VMGPPGPPGFPGERGQK--GDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 344 MI-------------KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLL 390 + K +Q + GV K D G D C + + Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGV----KGDKG-------------DTCFNC-------I 485 Query: 391 QSLRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVK 448 + SGPPG PG PG+ PPG G +G G G +P G+ G Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP----GIPGAPGAPGFP 541 Query: 449 AINQQTGAFVEI------SRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE------ 496 + G + +L G P L + G+P Q D L K E Sbjct: 542 GSKGEPGDILTFPGMKGDKGELGSPGAPG--LPGLPGTPGQ-DGLPGLPGPKGEPGGITF 598 Query: 497 ----GPLCPVGPG-PGGPGPAGPMGPFN---PGPF----------NQGPPGAPPHAGGP- 537 GP P PG PG PG GPMGP PGP N G PG P G P Sbjct: 599 KGERGP--PGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656 Query: 538 -----PPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGP-- 590 P P G P P P + + PPGP Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716 Query: 591 ---VPGPAPAPAAPPAQG--EPPQPP 611 +PGP AP P G PP PP Sbjct: 717 FPGIPGPPGAPGTPGRIGLEGPPGPP 742 Score = 59.3 bits (142), Expect = 1e-08 Identities = 100/354 (28%), Positives = 120/354 (33%), Gaps = 74/354 (20%) Query: 395 SGPPGPPGGPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGEN--- 446 SGPPG PG PG PG G G G GPPG G+ P + G G N Sbjct: 1136 SGPPGNPGLPG-EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194 Query: 447 --VKAINQQTG----AFVEISRQLP-PNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPL 499 + ++ Q G + + LP P G+P F F ++GP Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGF-----------------PGVQGPP 1237 Query: 500 CPVG-PGP------GGPGPAGPMG--PFNPGPFNQGPPGAPPHAG-----GPPPHQYPPQ 545 P G PGP G PGP GP G F P +GPPG P + G G P P Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPG 1297 Query: 546 GWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQG 605 G Q P +P + + + P VPG A P P Sbjct: 1298 LPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA-GPEGEPGLI 1356 Query: 606 EPPQPP----PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATG 661 PP PP P+GQS K + I QP G P Q Q Sbjct: 1357 GPPGPPGLPGPSGQSIIIKG-DAGPPGIPGQPGLKGLPGPQG----------PQGLPGPT 1405 Query: 662 GGPGAP-PGSQPDYSAAWAEYYRQQAAYYGQ--------TPGPGGPQPPPTQQG 706 G PG P P + A + GQ PGP G Q PP G Sbjct: 1406 GPPGDPGRNGLPGFDGAGGR--KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457 Score = 56.6 bits (135), Expect = 8e-08 Identities = 98/351 (27%), Positives = 113/351 (32%), Gaps = 81/351 (23%) Query: 396 GPPGPPGGPGMPPGGRGRGRGQ-GNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKA 449 GPPGP G PG+P GQ G GPPG G+M F P G Sbjct: 1003 GPPGPKGNPGLP--------GQPGLIGPPGLKGTIGDMGFPGPQGV------EGPPGPSG 1048 Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDH-------AKQLIEEKIEGPLCPV 502 + Q G+ + Q GDP + G P I+ + P P Sbjct: 1049 VPGQPGS-PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG 1107 Query: 503 GPG-------------PGGPGPAGPMG----PFNPG-PFNQGPPGAPPHAG--GPPPHQY 542 PG PG PGP GP G P NPG P GP G H G GPP + Sbjct: 1108 LPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKG 1167 Query: 543 PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPP 602 P G P Q P P +P S Q+ G +PG P P Sbjct: 1168 KPGQDGIPGPAGQKGEPGQP-----GFGNPGPPGLPGLSG--QKGDGGLPGIPGNPGLPG 1220 Query: 603 AQGEP-------PQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQ 655 +GEP Q PP A E G Q PG P Q Sbjct: 1221 PKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ-GPPGRPGFQGLP---------- 1269 Query: 656 AQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQG 706 GP PPG + + Q G PG G Q PP QG Sbjct: 1270 -------GPEGPPGLPGNGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQG 1312 Score = 52.4 bits (124), Expect = 1e-06 Identities = 89/340 (26%), Positives = 105/340 (30%), Gaps = 97/340 (28%) Query: 396 GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447 GP GPPG PG+P PG +G G GPPG IP GR G V Sbjct: 872 GPIGPPGSPGLPGKAGASGFPGTKGE---MGMMGPPGPPGPLGIP--------GRSG--V 918 Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP--G 505 + G ++G P + GP G Sbjct: 919 PGLKGDDG---------------------LQGQP------------GLPGPTGEKGSKGE 945 Query: 506 PGGPGPAGPMGPFNPGPFNQ-GPPGAP--PHAGGPPPHQYPPQGWGNTYPQWQP--PAPH 560 PG PGP GPM P G + G PG P P GP +Q P G QP P P Sbjct: 946 PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005 Query: 561 DPSKAAAAAADPNAAWAAYYSHYYQQP--PGP-----VPGPAPAPAAPPAQGEPPQPPPT 613 P P PGP PGP+ P P + G P Q Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065 Query: 614 GQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAP--PGS- 670 G + +P PG P + V G PG P PG+ Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGI----------KGSVGDPGLPGLPGTPGAK 1115 Query: 671 -QPDYSAAWAEYYRQQAAYYGQTPGPGGPQ---PPPTQQG 706 QP + TPGP GP+ PP G Sbjct: 1116 GQPGLPG------------FPGTPGPPGPKGISGPPGNPG 1143 Score = 47.0 bits (110), Expect = 6e-05 Identities = 95/358 (26%), Positives = 114/358 (31%), Gaps = 72/358 (20%) Query: 365 GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGP-- 422 GP I + G P ++ S GP G PG PG PPG +G G GP Sbjct: 147 GPPGIPGMKGEP----------GSIIMSSLPGPKGNPGYPG-PPGIQGLPGPTGIPGPIG 195 Query: 423 PGGEMTFSIPTHKCGLVIGRG--GENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS 480 P G P GL +G G N + + G E Q PP G Sbjct: 196 PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG---EQGLQGPP------------GP 240 Query: 481 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH 540 P QI K+ I+ + + + G PGP G GP PGP G G G P Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP--PGP-PGGEKGEKGEQGEPGKR 297 Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA 600 P + N P P P DP D PPGP P P Sbjct: 298 GKPGKDGENGQP-GIPGLPGDPGYPGEPGRDGEKGQKGDTG-----PPGPPGLVIPRPGT 351 Query: 601 PPAQGE------PPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK- 653 GE P P G E + I P PG P + Sbjct: 352 GITIGEKGNIGLPGLPGEKG--------ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403 Query: 654 KQAQVATGGGPG----APPG--SQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQ 705 ++ Q G PG PPG QP A PGP GP PP+ + Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPG------------APGLPGPPGPAGPHIPPSDE 449 Score = 46.2 bits (108), Expect = 1e-04 Identities = 29/66 (43%), Positives = 31/66 (46%), Gaps = 8/66 (12%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA------GDRGGGGPGG--GGPGGGSAGGPSQPP 62 PG P P G G G G PPGPPG+ G +G GP G G PG GP PP Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPP 1275 Query: 63 GGGGPG 68 G G G Sbjct: 1276 GLPGNG 1281 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/63 (44%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69 PGPP P G G G G PPG G GD G GP G G +G P QP G PG Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061 Query: 70 RKD 72 + D Sbjct: 1062 KGD 1064 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/76 (43%), Positives = 34/76 (44%), Gaps = 14/76 (18%) Query: 8 GPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRG-GGGPGGGGPGGGS 54 GPP PG P P GGGG G G G PG AG +G G PG G PG Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196 Query: 55 AGGPSQPPGGGG-PGI 69 G S G GG PGI Sbjct: 1197 LPGLSGQKGDGGLPGI 1212 Score = 44.7 bits (104), Expect = 3e-04 Identities = 30/69 (43%), Positives = 32/69 (46%), Gaps = 7/69 (10%) Query: 6 TGGPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPS 59 T GPP GPP G G G GGG PG PG G++G G G G G P Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185 Query: 60 QPPGGGGPG 68 Q PG G PG Sbjct: 1186 Q-PGFGNPG 1193 Score = 44.3 bits (103), Expect = 4e-04 Identities = 30/69 (43%), Positives = 32/69 (46%), Gaps = 6/69 (8%) Query: 10 PPGPPPPAGGG--GGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPG 63 PPGPP G G G G PPG PG G G PG G GG G G P QP Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1295 Query: 64 GGGPGIRKD 72 G PG++ D Sbjct: 1296 PGLPGLKGD 1304 Score = 43.5 bits (101), Expect = 7e-04 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 11/76 (14%) Query: 8 GPP----PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 GPP PGPP G G G G PPG PG + G G G GP PPG Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Query: 64 -------GGGPGIRKD 72 G PG++ D Sbjct: 909 PLGIPGRSGVPGLKGD 924 Score = 42.7 bits (99), Expect = 0.001 Identities = 61/216 (28%), Positives = 78/216 (36%), Gaps = 51/216 (23%) Query: 504 PG-PGGPGPAGPMGPFN----------PGPFN-QGP------------PGAPPHAGGPPP 539 PG PG PGP GP GP PGP +GP PG P H G P P Sbjct: 59 PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP 118 Query: 540 HQYP-----------PQGWGNTYPQWQPPAPHDPS-KAAAAAADPNAAWAAYYSHYYQQP 587 P P G Q P P P K + ++ + Y P Sbjct: 119 QGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP 178 Query: 588 PG--------PVPGPAPAPAAPPAQGEPPQPP--PTGQSDYTKAWEEYYKKIGQQPQQ-- 635 PG +PGP P PP PP PP P + + ++ + G+Q Q Sbjct: 179 PGIQGLPGPTGIPGPI-GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237 Query: 636 PGAPPQ-QDYTKAWEEYYKKQAQVATGG-GPGAPPG 669 PG P Q + + + ++K Q G GP PPG Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273 Score = 41.6 bits (96), Expect = 0.003 Identities = 32/75 (42%), Positives = 35/75 (46%), Gaps = 17/75 (22%) Query: 12 GPPPPAGGGGGAG--GAGGGPPPGPPG-AGDRGGGG-------PGGGGPGG-----GSAG 56 G P PAG G G G G PPG PG +G +G GG PG GP G G G Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232 Query: 57 --GPSQPPGGGGPGI 69 GP PPG GP + Sbjct: 1233 VQGPPGPPGSPGPAL 1247 Score = 41.6 bits (96), Expect = 0.003 Identities = 67/244 (27%), Positives = 76/244 (31%), Gaps = 46/244 (18%) Query: 396 GPPGPPGGPGMPPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 GPPGPPG PG P G G GPPG G P GL G GG + N Sbjct: 1235 GPPGPPGSPG--PALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLP-GNGGIKGEKGNPG 1291 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEG-PLCPVGPGPGG---- 508 + G P ++G+P + + + G P P GP G Sbjct: 1292 QPGLPGLPGLKGDQGPPG-----LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1346 Query: 509 ------------PGPAGPMGPFNPGPF---NQGPPGAPPHAG--GPPPHQYPPQGWGNTY 551 PGP G GP + GPPG P G G P Q P G T Sbjct: 1347 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1406 Query: 552 PQWQPPAPHDP--SKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQ 609 P P P A DP P P P P PP Sbjct: 1407 PPGDPGRNGLPGFDGAGGRKGDPGL------------PGQPGTRGLDGPPGPDGLQGPPG 1454 Query: 610 PPPT 613 PP T Sbjct: 1455 PPGT 1458 Score = 41.2 bits (95), Expect = 0.003 Identities = 28/62 (45%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGG-PGGGGP--GGGSAGGPSQPPGGGG 66 PG P G G G G PPGP G +G G G PG GP GGG G P P G Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168 Query: 67 PG 68 PG Sbjct: 1169 PG 1170 Score = 41.2 bits (95), Expect = 0.003 Identities = 28/68 (41%), Positives = 31/68 (45%), Gaps = 7/68 (10%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPG----GGSAGGPSQPP 62 P GPP G GG G G PG PG G +G GP G G PG G G P P Sbjct: 1271 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1330 Query: 63 GGGGPGIR 70 G PG++ Sbjct: 1331 VPGFPGMK 1338 Score = 40.8 bits (94), Expect = 0.004 Identities = 28/71 (39%), Positives = 31/71 (43%), Gaps = 12/71 (16%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGP------PGAGDRGGGG----PGGGGPGG--GSAGGP 58 PG P P G G G G PPGP G++G G PG GP G G G P Sbjct: 931 PGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP 990 Query: 59 SQPPGGGGPGI 69 QP G PG+ Sbjct: 991 GQPGLSGQPGL 1001 Score = 40.4 bits (93), Expect = 0.006 Identities = 31/73 (42%), Positives = 32/73 (43%), Gaps = 19/73 (26%) Query: 8 GPPPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGGGGPGG----GGPG-GGSAGGP 58 GPP P PP GA PPGPPG G +G GP G G PG G G P Sbjct: 380 GPPGLPGPP--------GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431 Query: 59 S--QPPGGGGPGI 69 PPG GP I Sbjct: 432 GLPGPPGPAGPHI 444 Score = 40.4 bits (93), Expect = 0.006 Identities = 32/78 (41%), Positives = 33/78 (42%), Gaps = 19/78 (24%) Query: 8 GPPP----GPPPPAGGGGGAGGAGG-GPP----PGPPGAGDRGG--GGPGGGGPGGG--- 53 GPP GPP P G G G G GPP PGPPG + G G PG GP G Sbjct: 386 GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445 Query: 54 -----SAGGPSQPPGGGG 66 GP PPG G Sbjct: 446 PSDEICEPGPPGPPGSPG 463 Score = 40.0 bits (92), Expect = 0.007 Identities = 32/71 (45%), Positives = 33/71 (46%), Gaps = 9/71 (12%) Query: 8 GPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRG-----GGGPG-GGGPG-GGSAGGP 58 GPP GPP P G G G AG PG PG GD G G PG G PG G G P Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680 Query: 59 SQPPGGGGPGI 69 P G PG+ Sbjct: 681 GDPGLPGQPGL 691 Score = 38.1 bits (87), Expect = 0.028 Identities = 31/72 (43%), Positives = 31/72 (43%), Gaps = 7/72 (9%) Query: 3 DYSTGGPP--PGPP--PPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSA 55 D G P PG P P G G G G PGPPG G G GP G G PG Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735 Query: 56 GGPSQPPGGGGP 67 GP PPG GP Sbjct: 736 EGPPGPPGFPGP 747 Score = 38.1 bits (87), Expect = 0.028 Identities = 34/87 (39%), Positives = 35/87 (40%), Gaps = 27/87 (31%) Query: 7 GGPPPGPPPPAGGGGGAGGAGGGP----------PPGPPG-------------AGDRG-G 42 G P P PP + G G GA G P PPGPPG GD G Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928 Query: 43 GGPGGGGPGG--GSAGGPSQPPGGGGP 67 G PG GP G GS G P PG GP Sbjct: 929 GQPGLPGPTGEKGSKGEPGL-PGPPGP 954 Score = 37.7 bits (86), Expect = 0.037 Identities = 29/65 (44%), Positives = 29/65 (44%), Gaps = 5/65 (7%) Query: 8 GPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63 GPP PG P G G G G P GPPG R G PG G GG G G P QP Sbjct: 1379 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGL-PGFDGAGGRKGDPGLPGQPGT 1437 Query: 64 GGGPG 68 G G Sbjct: 1438 RGLDG 1442 Score = 37.7 bits (86), Expect = 0.037 Identities = 27/60 (45%), Positives = 27/60 (45%), Gaps = 12/60 (20%) Query: 10 PPGPPPPAGGGG-----GAGGAGGGPP-PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 P GPP G G GAGG G P PG PG RG GP PG GP PPG Sbjct: 1404 PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT--RGLDGP----PGPDGLQGPPGPPG 1457 Score = 37.0 bits (84), Expect = 0.063 Identities = 27/65 (41%), Positives = 28/65 (43%), Gaps = 10/65 (15%) Query: 10 PPGPPPPAGGGGGA----GGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63 PPGPP G G + G AG PG PG G PG GP G G G P P Sbjct: 1358 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLK----GLPGPQGPQGLPGPTGPPGDPGR 1413 Query: 64 GGGPG 68 G PG Sbjct: 1414 NGLPG 1418 Score = 36.6 bits (83), Expect = 0.083 Identities = 29/64 (45%), Positives = 30/64 (46%), Gaps = 15/64 (23%) Query: 6 TGGPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGG--GSAG--GPS 59 TG P P GPP P G G PPGPPG G +G G GP G G G GP Sbjct: 188 TGIPGPIGPPGPPGLMG---------PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP 238 Query: 60 QPPG 63 PPG Sbjct: 239 GPPG 242 Score = 36.6 bits (83), Expect = 0.083 Identities = 27/63 (42%), Positives = 29/63 (46%), Gaps = 6/63 (9%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQP--PGG 64 PG P G G G G PG PGA + G G PG GP G G +G P P PG Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE 1147 Query: 65 GGP 67 GP Sbjct: 1148 PGP 1150 Score = 36.6 bits (83), Expect = 0.083 Identities = 45/170 (26%), Positives = 53/170 (31%), Gaps = 64/170 (37%) Query: 365 GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--PGGRGRGRGQGNWGP 422 GPE ++GPP ++ +GPPG PG PG+ PG +G G GP Sbjct: 1348 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1407 Query: 423 PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQ 482 PG +P G GG GDP Sbjct: 1408 PGDPGRNGLPGFD-----GAGGR---------------------KGDPGL---------- 1431 Query: 483 QIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFN-QGPPGAP 531 PG PG G GP PGP QGPPG P Sbjct: 1432 -----------------------PGQPGTRGLDGP--PGPDGLQGPPGPP 1456 Score = 36.2 bits (82), Expect = 0.11 Identities = 29/67 (43%), Positives = 29/67 (43%), Gaps = 6/67 (8%) Query: 8 GPPPGPPP--PAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGG-PGGGSAGGPSQPP 62 GP P P P G G G G PPG PG G G G PG G PG G PP Sbjct: 1249 GPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1308 Query: 63 G-GGGPG 68 G G PG Sbjct: 1309 GLQGNPG 1315 Score = 36.2 bits (82), Expect = 0.11 Identities = 31/78 (39%), Positives = 32/78 (41%), Gaps = 17/78 (21%) Query: 10 PPGPPPPAG------GGGGAGGAGGGP-------PPGPPGAGDRGG--GGPGGGG-PGGG 53 PPG P P+G G G G G P P GP G G G PG G PG Sbjct: 1361 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1420 Query: 54 SAGGPSQPPG-GGGPGIR 70 AGG PG G PG R Sbjct: 1421 GAGGRKGDPGLPGQPGTR 1438 Score = 35.8 bits (81), Expect = 0.14 Identities = 25/60 (41%), Positives = 25/60 (41%), Gaps = 3/60 (5%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPG-GGGPGGGSAGGPSQPPGGGGP 67 PGP P G G G G G PG GG G PG G PG GP P G GP Sbjct: 1393 PGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGP 1452 Score = 35.4 bits (80), Expect = 0.18 Identities = 31/79 (39%), Positives = 31/79 (39%), Gaps = 18/79 (22%) Query: 3 DYSTGGPPP--GPPPPAGGGGGAGGAGGGP-------------PPGPPGA-GDRG-GGGP 45 D GPP GPP P GG G G G P PG PG GD G G P Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324 Query: 46 GGGGPGGGSAG-GPSQPPG 63 G G G GP PPG Sbjct: 325 GRDGEKGQKGDTGPPGPPG 343 Score = 35.0 bits (79), Expect = 0.24 Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 11/71 (15%) Query: 8 GPP--PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGG-PGGGGPGGGSAGG 57 GPP PG P G G G G G PPGP G AG+ G G PG G G + Sbjct: 603 GPPGNPGLPGLPGNIGPMGPPGFG-PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661 Query: 58 PSQPPGGGGPG 68 P +P G PG Sbjct: 662 PGKPGLPGNPG 672 Score = 34.3 bits (77), Expect = 0.41 Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 6/65 (9%) Query: 12 GPPPPAGGGGGAGGAGGGPPPGPPGA----GDRGGGGPGGGGPGG--GSAGGPSQPPGGG 65 G P P G G G +G PG PG GD+G G G G G G P P G Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092 Query: 66 GPGIR 70 PGI+ Sbjct: 1093 NPGIK 1097 Score = 33.9 bits (76), Expect = 0.54 Identities = 29/78 (37%), Positives = 32/78 (41%), Gaps = 18/78 (23%) Query: 11 PGPPPPAGGG--GGAGGAGGGPPPGPPGA----------GDRG----GGGPGGGGPGG-- 52 PGPP P G G G PG PG GD G G PG GP G Sbjct: 949 PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008 Query: 53 GSAGGPSQPPGGGGPGIR 70 G+ G P QP G PG++ Sbjct: 1009 GNPGLPGQPGLIGPPGLK 1026 Score = 33.9 bits (76), Expect = 0.54 Identities = 27/64 (42%), Positives = 29/64 (45%), Gaps = 6/64 (9%) Query: 11 PGPP--PPAGGGGGAGGAGGGPP-PGPPGAGDRGG--GGPG-GGGPGGGSAGGPSQPPGG 64 PGPP P G G GG G P PG PG G G PG G PG + GP+ Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 65 GGPG 68 G PG Sbjct: 1252 GNPG 1255 Score = 33.5 bits (75), Expect = 0.70 Identities = 34/89 (38%), Positives = 35/89 (39%), Gaps = 28/89 (31%) Query: 8 GPP--------PGPPPPAG--------GGGGAGGAGGGPP-PGPPGA----GDRGGGG-- 44 GPP PGPP G G GA G G P PG PGA G +G G Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI 550 Query: 45 ---PGGGGPGG--GSAGGPSQPPGGGGPG 68 PG G G GS G P P G PG Sbjct: 551 LTFPGMKGDKGELGSPGAPGLPGLPGTPG 579 Score = 33.5 bits (75), Expect = 0.70 Identities = 25/66 (37%), Positives = 27/66 (40%), Gaps = 6/66 (9%) Query: 10 PPGPPPPAGGGGGAGGAG-GGPP-----PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63 PPG G G G G GPP PG PG+ G G PG S G P P Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081 Query: 64 GGGPGI 69 G PG+ Sbjct: 1082 KGEPGL 1087 Score = 33.1 bits (74), Expect = 0.92 Identities = 28/81 (34%), Positives = 31/81 (38%), Gaps = 21/81 (25%) Query: 11 PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGG------PGGGGPGG----------- 52 PGP G G +G G PG PG GD+G G PG GP G Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094 Query: 53 ---GSAGGPSQPPGGGGPGIR 70 GS G P P G PG + Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAK 1115 Score = 32.3 bits (72), Expect = 1.6 Identities = 21/58 (36%), Positives = 21/58 (36%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGP 67 P G P G G G G PG PG G G PG GP P G GP Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138 Score = 32.0 bits (71), Expect = 2.0 Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 12/72 (16%) Query: 10 PPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGG-GGPGGGGPGG-------GSAGG 57 PPGP G G G G G PG G++G G PG GP G GS G Sbjct: 906 PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965 Query: 58 PSQPPGGGGPGI 69 +P G PG+ Sbjct: 966 KGEPGLPGIPGV 977 Score = 30.4 bits (67), Expect = 5.9 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 6/65 (9%) Query: 11 PGPPPPAGGGGGAGGAGGGPP--PGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGG 64 PG P G G G + G P PGP G G G PG G G G G P P Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115 Query: 65 GGPGI 69 G PG+ Sbjct: 1116 GQPGL 1120 >gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 isoform a [Homo sapiens] Length = 599 Score = 72.8 bits (177), Expect = 1e-12 Identities = 85/350 (24%), Positives = 144/350 (41%), Gaps = 75/350 (21%) Query: 187 LPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAG 246 +P+ VS P+ Q+ D SR +G PG + Q I++P G Sbjct: 155 IPDEEVSSPSPPQRAQRG-----DHSSREQGHAPG---GTSQARQIDFPLRILVPTQFVG 206 Query: 247 LVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDIL-RE 305 +IGK G TIK + ++ ++ + + + +KP+ I P +AC M+++I+ +E Sbjct: 207 AIIGKEGLTIKNITKQTQSRVDIHRKENSGA-AEKPVTIHATPEGTSEACRMILEIMQKE 265 Query: 306 RDQGGFGDRNEYGSRIGGGIDVPVPRHS--VGVVIGRSGEMIKKIQNDAGVRIQFK--QD 361 D+ +++ I + + H+ VG +IG+ G +KKI+++ G +I QD Sbjct: 266 ADE----------TKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQD 315 Query: 362 DGT-GPEKIAHIMGPPDRCEHAARII---------NDLLQ-------------------- 391 PE+ + G + C A I ND+L Sbjct: 316 LSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFS 375 Query: 392 ---SLRSGPPGPPGGPGMPP--------GGRGRGRGQGNWGP-------PGGE-MTFSIP 432 S+ S P GP G P P G +GP P E + IP Sbjct: 376 TGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIP 435 Query: 433 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQ 482 T G +IG+ G ++K + + GA ++I+ P D + ++ II G P+ Sbjct: 436 TQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGP--DVSERMVIITGPPE 483 Score = 71.2 bits (173), Expect = 3e-12 Identities = 52/181 (28%), Positives = 90/181 (49%), Gaps = 15/181 (8%) Query: 133 QLGPI---HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSG-GLP 188 Q GP H P + + +P VG IIG+ G I ++ + +G ++I+P G + Sbjct: 414 QFGPFPHHHSYPEQEIVNLF-IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS 472 Query: 189 ERSVSLTGAPESVQKAK-MMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGL 247 ER V +TG PE+ KA+ + + P + A+ I +P+ AG Sbjct: 473 ERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAH---------IRVPSSTAGR 523 Query: 248 VIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERD 307 VIGKGG+T+ +LQ ++I+ +D + + N + +RIIG + Q A + +I+++ Sbjct: 524 VIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 583 Query: 308 Q 308 Q Sbjct: 584 Q 584 Score = 52.8 bits (125), Expect = 1e-06 Identities = 78/318 (24%), Positives = 126/318 (39%), Gaps = 75/318 (23%) Query: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQIS---PDSGGLPERSVSLTGAPESVQKAKMMLD 209 +G+VG +IG+ G + KI+ ++G K+ IS S PER++++ G E+ A++ + Sbjct: 283 NGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIM 342 Query: 210 -----------------------------DIVSRG----------RGGPP---------- 220 I S G RG PP Sbjct: 343 KKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTH 402 Query: 221 -GQFHDNANGGQNGTV--------QEIM---IPAGKAGLVIGKGGETIKQLQERAGVKMI 268 G F Q G QEI+ IP G +IGK G IKQL AG + Sbjct: 403 SGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIK 462 Query: 269 LIQDGSQNTNVDKPLRIIGDPYKVQ-QACEMVMDILRERDQGGFGDRNEYGSRIGGGIDV 327 + ++ +V + + II P + Q +A + L+E + F + E + + Sbjct: 463 IAP--AEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE--ENFFNPKEE----VKLEAHI 514 Query: 328 PVPRHSVGVVIGRSGEMIKKIQN--DAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385 VP + G VIG+ G+ + ++QN A V + Q E I I+G + A R Sbjct: 515 RVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRK 574 Query: 386 INDLLQSLRSGPPGPPGG 403 I +++Q ++ P G Sbjct: 575 IREIVQQVKQQEQKYPQG 592 Score = 50.1 bits (118), Expect = 7e-06 Identities = 68/285 (23%), Positives = 102/285 (35%), Gaps = 68/285 (23%) Query: 305 ERDQGGFGDRNEYGSRIGGG-----IDVP----VPRHSVGVVIGRSGEMIKKIQNDAGVR 355 +R Q G E G GG ID P VP VG +IG+ G IK I R Sbjct: 167 QRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSR 226 Query: 356 IQFKQDDGTGP-EKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRG 414 + + + +G EK I P+ A R+I +++Q Sbjct: 227 VDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQK---------------------- 264 Query: 415 RGQGNWGPPGGEMTFSIPTHK--CGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNF 472 + + E+ I H G +IG+ G N+K I +TG + IS + Sbjct: 265 --EADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPE 322 Query: 473 KLFIIRGSPQQIDHAK----QLIEEKIEGPLCPVG------PG----------------- 505 + ++G+ + A+ + + E E + V PG Sbjct: 323 RTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLS 382 Query: 506 -PGGPGPAGPMGPFNPGPFNQGPPGA--PPHAGGPPP--HQYPPQ 545 P GP A P P++P + G + P H GP P H YP Q Sbjct: 383 PPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQ 427 Score = 42.7 bits (99), Expect = 0.001 Identities = 36/149 (24%), Positives = 62/149 (41%), Gaps = 32/149 (21%) Query: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTG-PEKIAHIMGPPD-RCEHA 382 +++ +P +VG +IG+ G IK++ AG I+ +G E++ I GPP+ + + Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489 Query: 383 ARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFS----IPTHKCGL 438 RI L + N+ P E+ +P+ G Sbjct: 490 GRIFGKLKEE--------------------------NFFNPKEEVKLEAHIRVPSSTAGR 523 Query: 439 VIGRGGENVKAINQQTGAFVEISRQLPPN 467 VIG+GG+ V + T A V + R P+ Sbjct: 524 VIGKGGKTVNELQNLTSAEVIVPRDQTPD 552 Score = 33.1 bits (74), Expect = 0.92 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 13/102 (12%) Query: 401 PGGPGMPPGGRGRGRGQGNWGPPGGE---------MTFSIPTHKCGLVIGRGGENVKAIN 451 P P G R QG+ PGG + +PT G +IG+ G +K I Sbjct: 163 PSPPQRAQRGDHSSREQGH--APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNIT 220 Query: 452 QQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE 493 +QT + V+I R+ N K I +P+ A ++I E Sbjct: 221 KQTQSRVDIHRK--ENSGAAEKPVTIHATPEGTSEACRMILE 260 >gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] Length = 318 Score = 72.8 bits (177), Expect = 1e-12 Identities = 80/341 (23%), Positives = 141/341 (41%), Gaps = 58/341 (17%) Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215 VG IIG+ GE + K++++SG ++ IS G PER ++L G ++ KA M+ D + Sbjct: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 ++ + +++PA + G +IGKGG IK+++E G ++ + D Sbjct: 83 ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139 Query: 276 NTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSV 334 N + ++ + I G P + + + + ++ E G+ +P P+ S Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLESPP--------------KGVTIPYRPKPSS 184 Query: 335 GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394 VI G+ IQ + Q D T ++A + Sbjct: 185 SPVIFAGGQAY-TIQGQYAI----PQPDLTKLHQLA---------------------MQQ 218 Query: 395 SGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQT 454 S P G G G + + E+T IP G +IGR G + I Q + Sbjct: 219 SHFPMTHGNTGFSAGLDASAQTTSH------ELT--IPNDLIGCIIGRQGAKINEIRQMS 270 Query: 455 GAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495 GA ++I+ + + D + I GS I A+ LI ++ Sbjct: 271 GAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 308 Score = 69.7 bits (169), Expect = 9e-12 Identities = 53/190 (27%), Positives = 82/190 (43%), Gaps = 33/190 (17%) Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393 VG +IG+ GE +KK++ ++G RI + G PE+I + GP + A +I D L+ Sbjct: 25 VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82 Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 S PP + +P +CG +IG+GG +K I + Sbjct: 83 ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126 Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512 TGA V+++ + PN + I G PQ I+ KQ+ +E P P Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESP------------PK 172 Query: 513 GPMGPFNPGP 522 G P+ P P Sbjct: 173 GVTIPYRPKP 182 Score = 53.1 bits (126), Expect = 9e-07 Identities = 25/73 (34%), Positives = 47/73 (64%) Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205 + E +P+ ++G IIGR G +IN+I+Q SG +++I+ G +R V++TG+ S+ A+ Sbjct: 242 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 301 Query: 206 MMLDDIVSRGRGG 218 +++ +S GG Sbjct: 302 YLINVRLSSETGG 314 Score = 43.1 bits (100), Expect = 9e-04 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%) Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187 + ISS + R +T VP G +IG+GG +I +I++ +G +VQ++ D L Sbjct: 81 EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138 Query: 188 P---ERSVSLTGAPESV 201 P ER++++ G P+S+ Sbjct: 139 PNSTERAITIAGIPQSI 155 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.139 0.438 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 49,572,903 Number of Sequences: 37866 Number of extensions: 4200814 Number of successful extensions: 104053 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1178 Number of HSP's successfully gapped in prelim test: 1503 Number of HSP's that attempted gapping in prelim test: 23899 Number of HSP's gapped (non-prelim): 36176 length of query: 711 length of database: 18,247,518 effective HSP length: 109 effective length of query: 602 effective length of database: 14,120,124 effective search space: 8500314648 effective search space used: 8500314648 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.