Guide to the Human Genome
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Search of human proteins with 154355000

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
         (711 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154355000 KH-type splicing regulatory protein [Homo sapiens]      1515   0.0  
gi|17402900 far upstream element-binding protein [Homo sapiens]       798   0.0  
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo...   535   e-152
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       86   2e-16
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     85   2e-16
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]       85   2e-16
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    84   3e-16
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    84   3e-16
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    84   3e-16
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    84   3e-16
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    84   3e-16
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    84   3e-16
gi|222352151 poly(rC) binding protein 1 [Homo sapiens]                 82   2e-15
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      80   5e-15
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]       80   5e-15
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    80   5e-15
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       80   7e-15
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]       80   9e-15
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]        77   7e-14
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]       77   7e-14
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]        76   1e-13
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ...    75   2e-13
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]       75   2e-13
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    75   2e-13
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]       75   3e-13
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    73   8e-13
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    73   8e-13
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    73   8e-13
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ...    73   1e-12
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]       73   1e-12

>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 1515 bits (3923), Expect = 0.0
 Identities = 711/711 (100%), Positives = 711/711 (100%)

Query: 1   MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60
           MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ
Sbjct: 1   MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60

Query: 61  PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120
           PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES
Sbjct: 61  PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120

Query: 121 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI 180
           KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI
Sbjct: 121 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI 180

Query: 181 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI 240
           SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI
Sbjct: 181 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI 240

Query: 241 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM 300
           PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM
Sbjct: 241 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM 300

Query: 301 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360
           DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ
Sbjct: 301 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360

Query: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420
           DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW
Sbjct: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420

Query: 421 GPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS 480
           GPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS
Sbjct: 421 GPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS 480

Query: 481 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH 540
           PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH
Sbjct: 481 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH 540

Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA 600
           QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA
Sbjct: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA 600

Query: 601 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT 660
           PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT
Sbjct: 601 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT 660

Query: 661 GGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ 711
           GGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
Sbjct: 661 GGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ 711


>gi|17402900 far upstream element-binding protein [Homo sapiens]
          Length = 644

 Score =  798 bits (2060), Expect = 0.0
 Identities = 426/703 (60%), Positives = 487/703 (69%), Gaps = 96/703 (13%)

Query: 34  PPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAA 93
           PP +G  GGGG GGGG G                    DAF DA+QRARQIAAKIGGDA 
Sbjct: 9   PPSSGSAGGGGGGGGGGG------------------VNDAFKDALQRARQIAAKIGGDAG 50

Query: 94  TTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIH-PPPRTSMTEEYRVP 152
           T++N++  D+G+GGQKR LEDGDQP++KK+A Q DS  +QL P+H    R+ MTEEY+VP
Sbjct: 51  TSLNSN--DYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVP 108

Query: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIV 212
           DGMVG IIGRGGEQI++IQQ+SGCK+QI+PDSGGLPERS  LTG PESVQ AK +LD IV
Sbjct: 109 DGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIV 168

Query: 213 SRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQD 272
            +GR  P   FH     G    VQEIMIPA KAGLVIGKGGETIKQLQERAGVKM++IQD
Sbjct: 169 EKGRPAP--GFHH--GDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQD 224

Query: 273 GSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGD-RNEYGSRIGG--GIDVPV 329
           G QNT  DKPLRI GDPYKVQQA EMV++++  RDQGGF + RNEYGSRIGG  GIDVP+
Sbjct: 225 GPQNTGADKPLRITGDPYKVQQAKEMVLELI--RDQGGFREVRNEYGSRIGGNEGIDVPI 282

Query: 330 PRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDL 389
           PR +VG+VIGR+GEMIKKIQNDAGVRIQFK DDGT PE+IA I GPPDRC+HAA II DL
Sbjct: 283 PRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDL 342

Query: 390 LQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW--GPPGG--EMTFSIPTHKCGLVIGRGGE 445
           L+S+++G PG PG     PGGRGRGRGQGNW  GPPGG  E  F +PT K GL+IG+GGE
Sbjct: 343 LRSVQAGNPGGPG-----PGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGE 397

Query: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP- 504
            +K+I+QQ+GA +E+ R  PPN DPN KLF IRG+PQQID+A+QLIEEKI GP+ P+GP 
Sbjct: 398 TIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPP 457

Query: 505 -------------GPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTY 551
                         PG PGP  PMGP+NP P+N GPPG  PH    PP  Y PQGWGN Y
Sbjct: 458 VPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHG---PPAPYAPQGWGNAY 514

Query: 552 PQWQPPAPHDPSKAAAAAADPN-AAWAAYYSHYYQ---QPPGPVPGPAPAPAAPPAQGEP 607
           P WQ  AP DP+K   A  DPN AAWAAYY+HYYQ   QPP   P  AP       QG+ 
Sbjct: 515 PHWQQQAPPDPAK---AGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQ 571

Query: 608 PQPPPTGQSDYTKAWEEYYKKIGQQ-PQQPGAPP--QQDYTKAWEEYYKKQAQVATGGGP 664
             P P GQ DYTKAWEEYYKK+GQ  P   GAPP  Q DY+ AW EYY+           
Sbjct: 572 QNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYR----------- 620

Query: 665 GAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQ 707
                              QQAAYY QT   G PQ PP  QGQ
Sbjct: 621 -------------------QQAAYYAQTSPQGMPQHPPAPQGQ 644



 Score =  643 bits (1658), Expect = 0.0
 Identities = 379/675 (56%), Positives = 436/675 (64%), Gaps = 127/675 (18%)

Query: 50  PGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQK 109
           P  GSAGG     GGGG G   DAF DA+QRARQIAAKIGGDA T++N++  D+G+GGQK
Sbjct: 10  PSSGSAGGGG---GGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSN--DYGYGGQK 64

Query: 110 RQLEDGDQPESKKLASQGDSISSQLGPIHPPP-RTSMTEEYRVPDGMVGLIIGRGGEQIN 168
           R LEDGDQP++KK+A Q DS  +QL P+H    R+ MTEEY+VPDGMVG IIGRGGEQI+
Sbjct: 65  RPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQIS 124

Query: 169 KIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNAN 228
           +IQQ+SGCK+QI+PDSGGLPERS  LTG PESVQ AK +LD IV +GR  P   FH    
Sbjct: 125 RIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPG--FHHG-- 180

Query: 229 GGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGD 288
            G    VQEIMIPA KAGLVIGKGGETIKQLQERAGVKM++IQDG QNT  DKPLRI GD
Sbjct: 181 DGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGD 240

Query: 289 PYKVQQACEMVMDILRERDQGGFGD-RNEYGSRIGG--GIDVPVPRHSVGVVIGRSGEMI 345
           PYKVQQA EMV++++R  DQGGF + RNEYGSRIGG  GIDVP+PR +VG+VIGR+GEMI
Sbjct: 241 PYKVQQAKEMVLELIR--DQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMI 298

Query: 346 KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPG 405
           KKIQNDAGVRIQFK DDGT PE+IA I GPPDRC+HAA II DLL+S+++G PG PG   
Sbjct: 299 KKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPG--- 355

Query: 406 MPPGGRGRGRGQGNW--GPPGG--EMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEIS 461
             PGGRGRGRGQGNW  GPPGG  E  F +PT K GL+IG+GGE +K+I+QQ+GA +E+ 
Sbjct: 356 --PGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQ 413

Query: 462 RQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPG 521
           R  PPN DPN KLF IRG+PQQID+A+QLIEEKI GP+ P+GP    P P GP G   PG
Sbjct: 414 RNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGP----PVPHGPHGV--PG 467

Query: 522 PFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYS 581
           P   GPPG        PP    P G  N       PAP++P                   
Sbjct: 468 P--HGPPG--------PPGPGTPMGPYN-------PAPYNPG------------------ 492

Query: 582 HYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQ 641
                PPGP P   PAP AP                  + W   Y    QQ     APP 
Sbjct: 493 -----PPGPAPHGPPAPYAP------------------QGWGNAYPHWQQQ-----APPD 524

Query: 642 QDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQ 699
                                   A  G+ P+ SAAWA YY   A YY Q   P P  P 
Sbjct: 525 P-----------------------AKAGTDPN-SAAWAAYY---AHYYQQQAQPPPAAPA 557

Query: 700 PPPTQ-----QGQQQ 709
             PT      QG QQ
Sbjct: 558 GAPTTTQTNGQGDQQ 572



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 34/93 (36%), Positives = 38/93 (40%), Gaps = 17/93 (18%)

Query: 7   GGP-----PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG---GGPGGGGPGGGSAGGP 58
           GGP     PP P  P G  G  G      PPGPPG G   G     P   GP G +  GP
Sbjct: 448 GGPVNPLGPPVPHGPHGVPGPHG------PPGPPGPGTPMGPYNPAPYNPGPPGPAPHGP 501

Query: 59  SQPPGGGGPGIRKDAFADAVQRARQIAAKIGGD 91
             P    G G   +A+    Q+A    AK G D
Sbjct: 502 PAPYAPQGWG---NAYPHWQQQAPPDPAKAGTD 531


>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
           sapiens]
          Length = 572

 Score =  535 bits (1378), Expect = e-152
 Identities = 310/638 (48%), Positives = 403/638 (63%), Gaps = 98/638 (15%)

Query: 68  GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTP-----DFGFGGQKRQLEDGDQPESKK 122
           G++ + F DA+ R RQIAAKI  D+   +NNSTP      +G+G QKR L+DG       
Sbjct: 13  GMKAEGFVDALHRVRQIAAKI--DSIPHLNNSTPLVDPSVYGYGVQKRPLDDG------- 63

Query: 123 LASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISP 182
                  + +QLG +    RT +TEE++VPD MVG IIGRGGEQI++IQ +SGCK+QI+ 
Sbjct: 64  -------VGNQLGAL-VHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIAS 115

Query: 183 DSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPA 242
           +S G+PER   LTG PES+++AK +L  IV R R GP   FH++ +   N T+QEI+IPA
Sbjct: 116 ESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPG--FHNDIDS--NSTIQEILIPA 171

Query: 243 GKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDI 302
            K GLVIG+GGETIKQLQER GVKM++IQDG   T  DKPLRI GD +KVQQA EMV++I
Sbjct: 172 SKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEI 231

Query: 303 LRERDQGGF-GDRNEYGSRIGGG-IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360
           +RE+DQ  F G R ++ SR+GGG I+V VPR +VG+VIGR+GEMIKKIQNDAGVRIQFK 
Sbjct: 232 IREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKP 291

Query: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420
           DDG  PE+ A +MGPPDRC+HAA II++L+ + +        G G     RGRGRG+G+W
Sbjct: 292 DDGISPERAAQVMGPPDRCQHAAHIISELILTAQERD-----GFGGLAAARGRGRGRGDW 346

Query: 421 --GPPGG--EMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFI 476
             G PGG  E+T+++P  KCGLVIG+GGEN+K+INQQ+GA VE+ R  PPN DPN + F 
Sbjct: 347 SVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFT 406

Query: 477 IRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGG 536
           IRG PQQI+ A+QLI+EK+           GG     P G F   PF+Q P  APPH   
Sbjct: 407 IRGVPQQIEVARQLIDEKV-----------GGTNLGAP-GAFGQSPFSQPP--APPHQ-- 450

Query: 537 PPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAP 596
              + +PP+  G             P+ AA    +P++               PV GP  
Sbjct: 451 ---NTFPPRSSGCF-----------PNMAAKVNGNPHST--------------PVSGP-- 480

Query: 597 APAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQA 656
                      P     G     +AW++  +++  Q  QP +  Q +Y+KAWE+YYKKQ+
Sbjct: 481 -----------PAFLTQGWGSTYQAWQQPTQQVPSQQSQPQSS-QPNYSKAWEDYYKKQS 528

Query: 657 QVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPG 694
             A+     + P   PDY+ AWAEYYRQQ A+YGQT G
Sbjct: 529 HAASAAPQASSP---PDYTMAWAEYYRQQVAFYGQTLG 563


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 193/763 (25%), Positives = 245/763 (32%), Gaps = 159/763 (20%)

Query: 7    GGPPPGPPPPAGGGGGAGGAGGGPP------PGPPG--AGDRGGGGPGGGGPGG--GSAG 56
            G   PG P P G  G  G  G   P      PGP G   GD   G PG  GP G  G  G
Sbjct: 899  GRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTG 958

Query: 57   --GPSQPPG-------GGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGG 107
              GP  PPG        G PG R +               +G    T       + G  G
Sbjct: 959  FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG 1018

Query: 108  QKRQL-EDGDQPESKKLASQGDSISSQL-GPIHPPPRTSMTEEYRVPDGMVGLIIGRGGE 165
                  E G    + K  ++GD   + L G   PP       +  +P G VG +  +G E
Sbjct: 1019 PPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLP-GPVGALGLKGNE 1077

Query: 166  QINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHD 225
                    +G   +  P     P   + + G P                G  GPPG   +
Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGP---IGIPGRP----------------GPQGPPGPAGE 1118

Query: 226  NANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285
                G+ G       PAG+ GL    G      L   AG      +DG +          
Sbjct: 1119 KGAPGEKGP----QGPAGRDGLQGPVG------LPGPAGPVGPPGEDGDKGE-------- 1160

Query: 286  IGDPYKVQQACEMVMDILRERDQGGFGDRNEYG----SRIGGGIDVPVPRHSVGVVIGRS 341
            IG+P                  +G  GD+ E G    +   G I  P P  + G    R 
Sbjct: 1161 IGEP----------------GQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG 1204

Query: 342  GEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPP 401
             + +   + D G R         GP  +  + GPP        +        + GPPGPP
Sbjct: 1205 QQGLFGQKGDEGPR---GFPGPPGPVGLQGLPGPPGEKGETGDV-------GQMGPPGPP 1254

Query: 402  G-----------GPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAI 450
            G           GP  PPGG G     G  G PG      +P  + G    +G    K  
Sbjct: 1255 GPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLP-GEGGPPGPKGERGEKGE 1313

Query: 451  NQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPL-CPVGPG-PGG 508
            +  +GA      + PP  D        +GSP               GP+  P  PG PG 
Sbjct: 1314 SGPSGAAGPPGPKGPPGDDGP------KGSP---------------GPVGFPGDPGPPGE 1352

Query: 509  PGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDP------ 562
            PGPAG  GP    P ++G  G P   G P P   P  G      +  PP P  P      
Sbjct: 1353 PGPAGQDGP----PGDKGDDGEPGQTGSPGPTGEP--GPSGPPGKRGPPGPAGPEGRQGE 1406

Query: 563  --SKAAAAAADPNAAWAAYYSHYYQQPPGP-----VPGP--------APAPAAPPAQGEP 607
              +K  A    P               PGP     +PGP        +P P  PP    P
Sbjct: 1407 KGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGP 1466

Query: 608  PQPPPTGQSDYTKAWEEYYKKIG--QQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG--- 662
            P  P        K  + +   IG    P + G    +           K  Q  TG    
Sbjct: 1467 PGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGP 1526

Query: 663  -GPGAPPGSQPDYSAAWAEYYRQQAAYYGQT--PGPGGPQPPP 702
             GP  PPG         A+         G+   PGP GP  PP
Sbjct: 1527 IGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPP 1569



 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 202/772 (26%), Positives = 247/772 (31%), Gaps = 163/772 (21%)

Query: 8    GPPPGPPPPA-GGGGGAGGAGG-----GPP-----------PGPPGAGDRGGGGPGGGGP 50
            GP   P PP   G  GA G  G     GPP           PG PGA D   G PG  GP
Sbjct: 712  GPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGA-DGPPGHPGKEGP 770

Query: 51   GGGSAG-GPSQPPGG-GGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQ 108
             G   G GP  P G  G PG R    AD ++  +    + G D          D G  G 
Sbjct: 771  PGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKG---DMGIKGD 827

Query: 109  KRQL-------EDGDQPESKKLASQGDSISSQLGPIHPP--------PRTSMTEEYRVPD 153
            + ++       EDG +    +    GD      GP+ PP        P        + P 
Sbjct: 828  RGEIGPPGPRGEDGPEGPKGRGGPNGDP-----GPLGPPGEKGKLGVPGLPGYPGRQGPK 882

Query: 154  GMVGL--IIGRGGEQINK-IQQDSGCKVQISPDSGGLPERSV-SLTGAPESVQKAKMMLD 209
            G +G     G  GE+  +      G + Q  P +G   ER    +TG P     +     
Sbjct: 883  GSIGFPGFPGANGEKGGRGTPGKPGPRGQRGP-TGPRGERGPRGITGKPGPKGNSG---- 937

Query: 210  DIVSRGRGGPPGQFHDNANGGQNG--TVQEIMIPAGKAGLV--IGKGGETIKQLQERAGV 265
                 G  GPPG+   N   G  G    +    P GK GL    G+ GET  Q       
Sbjct: 938  ---GDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ------- 987

Query: 266  KMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGI 325
                       T    P  ++G                    QG  G+    G R   G 
Sbjct: 988  ---------GKTGPPGPPGVVG-------------------PQGPTGETGPMGERGHPGP 1019

Query: 326  DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
              P     +  + G+ G      + D G      +D   G        G P         
Sbjct: 1020 PGPPGEQGLPGLAGKEG-----TKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP------- 1067

Query: 386  INDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRG 443
            +  L      GPPGPP GP   PG RG     G  G PG  G      P  + G    +G
Sbjct: 1068 VGALGLKGNEGPPGPP-GPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKG 1126

Query: 444  GENVKAINQQTG--AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCP 501
             +     +   G       +  + P G+   K  I  G P Q        E+   GP  P
Sbjct: 1127 PQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEI--GEPGQKGSKGDKGEQGPPGPTGP 1184

Query: 502  VG----PGPGG----PGPAGPMGPF----NPGPFNQGPPGAPPHAG-----GPPPHQYPP 544
             G    PGP G    PGP G  G F    + GP  +G PG P   G     GPP  +   
Sbjct: 1185 QGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP--RGFPGPPGPVGLQGLPGPPGEKGET 1242

Query: 545  QGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV--PGPAPAPAAPP 602
               G   P   PP P  PS A  A                Q PPG +  PG       P 
Sbjct: 1243 GDVGQMGPP-GPPGPRGPSGAPGADGP-------------QGPPGGIGNPGAVGEKGEPG 1288

Query: 603  AQGEPPQP---PPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVA 659
              GEP  P    P G         E        P  P  PP  D  K           V 
Sbjct: 1289 EAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG------SPGPVG 1342

Query: 660  TGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPG-----GPQPPPTQQG 706
              G PG PPG             +      GQT  PG     GP  PP ++G
Sbjct: 1343 FPGDPG-PPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRG 1393



 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 197/747 (26%), Positives = 253/747 (33%), Gaps = 133/747 (17%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGG-GPGG--GSAGGPSQPPGGG 65
            P GPP P G  G  G  G   P G PG  G RG  GP G  GP G  G  G   QP   G
Sbjct: 650  PSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKG 709

Query: 66   GPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLAS 125
              G + +      Q         G   A  +       G  G+K  L     P       
Sbjct: 710  NVGPQGEPGPPGQQ---------GNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMP---- 756

Query: 126  QGDSISSQLGPIHP----PPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQIS 181
                  +   P HP    PP     +    P G +G    RG +  + I+   G K +  
Sbjct: 757  -----GADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKG 811

Query: 182  PDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIP 241
             D  G P     +      ++  +  +     RG  GP G       GG NG    +  P
Sbjct: 812  ED--GFPGFKGDM-----GIKGDRGEIGPPGPRGEDGPEGP---KGRGGPNGDPGPLGPP 861

Query: 242  AGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMD 301
              K  L    G   +     R G K  +   G    N +K  R  G P K     +    
Sbjct: 862  GEKGKL----GVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGR--GTPGKPGPRGQ---- 911

Query: 302  ILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQD 361
                  +G  G R E G R  G    P P+ + G   G +G   ++  N           
Sbjct: 912  ------RGPTGPRGERGPR--GITGKPGPKGNSGGD-GPAGPPGERGPN----------- 951

Query: 362  DGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--PGGRGRGRGQGN 419
               GP+      GP                    GPPGPPG  G+P  PG RG    QG 
Sbjct: 952  ---GPQGPTGFPGP-------------------KGPPGPPGKDGLPGHPGQRGETGFQGK 989

Query: 420  WGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQTG----AFVEISRQLP-------P 466
             GPPG  G +    PT + G +  RG         + G    A  E ++  P        
Sbjct: 990  TGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGK 1049

Query: 467  NGDPNFKLFI-IRGSPQQIDHAKQLIEEKIEGPLCPVG-PGPGGP-GPAGPMG-PFNPGP 522
            +G P  + F   RG P  +        E   GP  P G PG  GP G AGP+G P  PGP
Sbjct: 1050 DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGP 1109

Query: 523  FNQGPPGAPPHAGGPPPHQYP--PQGWGNTYPQWQPPAPHDPSKAAAAAADPN-----AA 575
              QGPPG P    G P  + P  P G          P P  P        D         
Sbjct: 1110 --QGPPG-PAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQ 1166

Query: 576  WAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSD-YTKAWEEYYKKIGQQPQ 634
              +      Q PPGP  GP      P   G   +P P GQ   + +  +E  +     P 
Sbjct: 1167 KGSKGDKGEQGPPGPT-GPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225

Query: 635  Q------PGAPPQQDYTKAWEEYYKKQAQVATG--GGPGA-----PPGSQPDYSAAWAEY 681
                   PG P ++  T    +          G  G PGA     PPG   +  A   + 
Sbjct: 1226 PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKG 1285

Query: 682  YRQQAAYYGQTPGPGGPQPPPTQQGQQ 708
               +A   G  PG GGP  P  ++G++
Sbjct: 1286 EPGEAGEPG-LPGEGGPPGPKGERGEK 1311



 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 195/762 (25%), Positives = 243/762 (31%), Gaps = 144/762 (18%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAG-GPSQPPGG-GGPG 68
            PGP    G  G  G  G    PG PGA D   G PG  GP G   G GP  P G  G PG
Sbjct: 732  PGPQGAIGPPGEKGPLGKPGLPGMPGA-DGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPG 790

Query: 69   IRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQL-------EDGDQPESK 121
             R    AD ++  +    + G D          D G  G + ++       EDG +    
Sbjct: 791  PRGVKGADGIRGLKGTKGEKGEDGFPGFKG---DMGIKGDRGEIGPPGPRGEDGPEGPKG 847

Query: 122  KLASQGDSISSQLGPIHPP--------PRTSMTEEYRVPDGMVGL--IIGRGGEQINK-I 170
            +    GD      GP+ PP        P        + P G +G     G  GE+  +  
Sbjct: 848  RGGPNGDP-----GPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGT 902

Query: 171  QQDSGCKVQISPDSGGLPERSV-SLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANG 229
                G + Q  P +G   ER    +TG P     +          G  GPPG+   N   
Sbjct: 903  PGKPGPRGQRGP-TGPRGERGPRGITGKPGPKGNSG-------GDGPAGPPGERGPNGPQ 954

Query: 230  GQNGTV--QEIMIPAGKAGLV--IGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285
            G  G    +    P GK GL    G+ GET  Q                  T    P  +
Sbjct: 955  GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ----------------GKTGPPGPPGV 998

Query: 286  IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMI 345
            +G                    QG  G+    G R   G   P     +  + G+ G   
Sbjct: 999  VGP-------------------QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGT-- 1037

Query: 346  KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPG 405
               + D G      +D   G        G P         +  L      GPPGPPG P 
Sbjct: 1038 ---KGDPGPAGLPGKDGPPGLRGFPGDRGLPGP-------VGALGLKGNEGPPGPPG-PA 1086

Query: 406  MPPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQTG--AFVEIS 461
              PG RG     G  G PG  G      P  + G    +G +     +   G       +
Sbjct: 1087 GSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPA 1146

Query: 462  RQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP----GPGG----PGPAG 513
              + P G+   K  I  G P Q        E+   GP  P GP    GP G    PGP G
Sbjct: 1147 GPVGPPGEDGDKGEI--GEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG 1204

Query: 514  PMGPF----NPGPFNQGPPGAPPHAG-----GPPPHQYPPQGWGNTYPQWQPPAPHDPSK 564
              G F    + GP  +G PG P   G     GPP  +      G   P   PP P  PS 
Sbjct: 1205 QQGLFGQKGDEGP--RGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPG-PPGPRGPSG 1261

Query: 565  AAAAAADPNAAWAAYYSHYYQQPPGPV--PGPAPAPAAPPAQGEPPQPP---PTGQSDYT 619
            A  A                Q PPG +  PG       P   GEP  P    P G     
Sbjct: 1262 APGADGP-------------QGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGER 1308

Query: 620  KAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPG-----APPGSQPDY 674
                E        P  P  PP  D  K               G PG      PPG + D 
Sbjct: 1309 GEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDD 1368

Query: 675  SAAWAEYYRQQAAYYGQTPGPG-----GPQPPPTQQGQQQAQ 711
                           G +  PG     GP  P  +QG++ A+
Sbjct: 1369 GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAK 1410



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 191/773 (24%), Positives = 250/773 (32%), Gaps = 155/773 (20%)

Query: 8    GPP--------PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPS 59
            GPP        PGPP   G  G  G  G   PPG PG      G  G  GP G     P 
Sbjct: 469  GPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLP----GADGLPGPPGTMLMLPF 524

Query: 60   QPPGGGGPGIR------KDAFADAVQRARQIAAK--IGGDAATTVNNSTPDFGFGGQKRQ 111
            +  GGG  G +      +++ A A+ +  ++A +   G    T         G GG K  
Sbjct: 525  RFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKG- 583

Query: 112  LEDGDQPESKKLASQGDSISSQLGPIHPPPRTSM--TEEYRVPDGMVGLIIGRGGEQINK 169
             E GD         QG       GP   P R     ++  R   G  G    RG + +  
Sbjct: 584  -EPGDVGPQGPRGVQGPP-----GPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAG 637

Query: 170  IQQDSGCKVQISPDS-----GGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFH 224
            +  + G +    P       G   ER       P  +         +  +G  GPPG   
Sbjct: 638  LPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPG 697

Query: 225  DNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLR 284
                 GQ G       P G     +G  GE     Q+           G+Q   +  P  
Sbjct: 698  VTGMDGQPG-------PKGN----VGPQGEPGPPGQQG--------NPGAQ--GLPGPQG 736

Query: 285  IIGDPYKVQQACEMVMDILRERD--QGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSG 342
             IG P +     +  +  +   D   G  G     G +  GG   P P+  +G    R  
Sbjct: 737  AIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEK--GGQGPPGPQGPIGYPGPRGV 794

Query: 343  EMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPG 402
            +    I+   G + +  +D   G +    I G  DR E               GPPGP G
Sbjct: 795  KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKG--DRGE--------------IGPPGPRG 838

Query: 403  GPGMPPGGRGRGRGQGN---WGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVE 459
              G P G +GRG   G+    GPPG +    +P    GL    G +  K      G F  
Sbjct: 839  EDG-PEGPKGRGGPNGDPGPLGPPGEKGKLGVP----GLPGYPGRQGPKGSIGFPG-FPG 892

Query: 460  ISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG-PGP----GGPGPAGP 514
             + +    G P        G P               GP    G PGP    GG GPAGP
Sbjct: 893  ANGEKGGRGTP--------GKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGP 944

Query: 515  MGPFNPG--------PFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAA 566
             G   P         P  +GPPG PP   G P H   P   G T  Q +   P  P    
Sbjct: 945  PGERGPNGPQGPTGFPGPKGPPG-PPGKDGLPGH---PGQRGETGFQGKTGPPGPP--GV 998

Query: 567  AAAADPNAAWAAYYSHYYQQPPGP-----VPGPA--------PAPAAPPAQGEPP----- 608
                 P           +  PPGP     +PG A        P PA  P +  PP     
Sbjct: 999  VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGF 1058

Query: 609  -----QPPPTGQSDYTKAWEEYYKKIGQQPQQ-PGAPPQQDYTKAWEEYYKKQAQVATGG 662
                  P P G              +G +  + P  PP    +            +   G
Sbjct: 1059 PGDRGLPGPVG-------------ALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105

Query: 663  --GPGAPPGSQPDYSAAWAEYYRQQAAYYG-----QTPGPGGPQPPPTQQGQQ 708
              GP  PPG   +  A   +  +  A   G       PGP GP  PP + G +
Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDK 1158



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 188/746 (25%), Positives = 228/746 (30%), Gaps = 165/746 (22%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPPGGGGPG 68
            PGP  P G GG  G  G   P GP G   +G  GP G  G  G   + G    PG  GP 
Sbjct: 570  PGPVGPPGSGGLKGEPGDVGPQGPRGV--QGPPGPAGKPGRRGRAGSDGARGMPGQTGP- 626

Query: 69   IRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGD 128
             + D   D +          G    +       D G        E GD  E       G+
Sbjct: 627  -KGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDG--------ERGDDGEVGPRGLPGE 677

Query: 129  -SISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKV--QISPDSG 185
                  LGP  PP           P G+ G+  G+ G + N   Q        Q +P + 
Sbjct: 678  PGPRGLLGPKGPPGPPG-------PPGVTGMD-GQPGPKGNVGPQGEPGPPGQQGNPGAQ 729

Query: 186  GLPERSVSLTGAPESVQKAKMMLDDIVSR-------GRGGPPGQFHDNANGGQNGTVQEI 238
            GLP    ++    E     K  L  +          G+ GPPG+       G  G     
Sbjct: 730  GLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQG----- 784

Query: 239  MIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEM 298
              P G  G    KG + I+ L+   G K    +DG      D  ++              
Sbjct: 785  --PIGYPGPRGVKGADGIRGLKGTKGEKG---EDGFPGFKGDMGIK-------------- 825

Query: 299  VMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQF 358
                         GDR E G     G D P      G   G  G +              
Sbjct: 826  -------------GDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPL-------------- 858

Query: 359  KQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQG 418
                  GP      +G P    +  R           GP G  G PG P G  G   G+G
Sbjct: 859  ------GPPGEKGKLGVPGLPGYPGR----------QGPKGSIGFPGFP-GANGEKGGRG 901

Query: 419  NWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLP-----------PN 467
              G PG       P  + G    RG    + I  + G         P           P 
Sbjct: 902  TPGKPG-------PRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQ 954

Query: 468  GDPNFKLFIIRGSPQQID----HAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPF 523
            G   F        P   D    H  Q  E   +G   P GP PG  GP GP G    GP 
Sbjct: 955  GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP-PGVVGPQGPTG--ETGPM 1011

Query: 524  NQ-GPPGAPPHAGGPPPHQYPPQGWGNTYPQWQP-----PAPHDPSKAAAAAADPNAAW- 576
             + G PG P    GPP  Q  P   G    +  P     P    P        D      
Sbjct: 1012 GERGHPGPP----GPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP 1067

Query: 577  -AAYYSHYYQQPPGPVPGPA-------PAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKK 628
              A      + PPGP PGPA       PA AA P  G P +P P G            +K
Sbjct: 1068 VGALGLKGNEGPPGP-PGPAGSPGERGPAGAAGPI-GIPGRPGPQGPPGPAG------EK 1119

Query: 629  IGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG--GPGAPPGSQPDYSAAWAEYYRQQA 686
                 + P  P  +D           Q  V   G  GP  PPG   D         +   
Sbjct: 1120 GAPGEKGPQGPAGRDGL---------QGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSK 1170

Query: 687  AYYGQT--PGPGGPQPPPTQQGQQQA 710
               G+   PGP GPQ P  Q G   A
Sbjct: 1171 GDKGEQGPPGPTGPQGPIGQPGPSGA 1196



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 78/252 (30%), Positives = 89/252 (35%), Gaps = 54/252 (21%)

Query: 396  GPPGPPGGPGM-----PPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVK 448
            G PGPPG PG      PPG +G     G  G PG  GE   S P  K G     G E  +
Sbjct: 1345 GDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQ 1404

Query: 449  AINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG--P 506
                + GA  E   + PP            G P           + + G   PVG    P
Sbjct: 1405 G---EKGAKGEAGLEGPPGKTGPIGPQGAPGKPGP---------DGLRGIPGPVGEQGLP 1452

Query: 507  GGPGPAGPMGPFNPGPF-----NQGPPGAPPHAG-----GPPPHQYP------PQGWGNT 550
            G PGP GP GP  P        + GP G   H G     GPP  Q        P   G++
Sbjct: 1453 GSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSS 1512

Query: 551  YPQWQ-----PPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAA 600
             P+ +     P  P  P         P    A   S     P GP      PGP P P  
Sbjct: 1513 GPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSS----GPTGPKGEAGHPGP-PGPPG 1567

Query: 601  PPAQGEPPQPPP 612
            PP  GE  QP P
Sbjct: 1568 PP--GEVIQPLP 1577



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 80/327 (24%), Positives = 97/327 (29%), Gaps = 60/327 (18%)

Query: 393 LRSGPPGPPGGPGMP-PGGRGRGRGQ----GNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447
           L  GPPGP G  G+P P G     GQ    G  GPPG                  G    
Sbjct: 466 LIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRP----------------GLPGA 509

Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPG 507
             +    G  + +  +    GD   K  ++     Q     Q     + GP  P+G   G
Sbjct: 510 DGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGL-TG 568

Query: 508 GPGPAGP--MGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKA 565
            PGP GP   G     P + GP G P    GPP     P   G          P      
Sbjct: 569 RPGPVGPPGSGGLKGEPGDVGPQG-PRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPK 627

Query: 566 AAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE------PPQPPPTGQSDYT 619
                D  A       H     P   PGP          GE      P +P P G     
Sbjct: 628 GDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLG-- 685

Query: 620 KAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWA 679
                        P+ P  PP        +     +  V   G PG PPG Q +  A   
Sbjct: 686 -------------PKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPG-PPGQQGNPGAQ-- 729

Query: 680 EYYRQQAAYYGQTPGPGGPQPPPTQQG 706
                        PGP G   PP ++G
Sbjct: 730 -----------GLPGPQGAIGPPGEKG 745



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 69/260 (26%), Positives = 91/260 (35%), Gaps = 38/260 (14%)

Query: 5    STGGPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGG-----GGPGGGSAGG 57
            + G P P GPP   G  G  G  G    PGPPG  G  G  GP G     G PG   + G
Sbjct: 1319 AAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPG 1378

Query: 58   PSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAAT--TVNNSTPDFGFGGQKRQLEDG 115
            P+  PG  GP  ++     A    RQ      G+A        + P    G   +   DG
Sbjct: 1379 PTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDG 1438

Query: 116  DQPESKKLASQG----DSISSQLGPIHPPPRTSMTEE-----YRVPDGMVGLIIGRGGEQ 166
             +     +  QG           GP+ PP    +  +      +   G++GL IG  GEQ
Sbjct: 1439 LRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGL-IGPPGEQ 1497

Query: 167  INKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDN 226
              K     G +    P     P+    +TG    +             G  GPPG     
Sbjct: 1498 GEK-----GDRGLPGPQGSSGPKGEQGITGPSGPIGPPG-------PPGLPGPPGPKGAK 1545

Query: 227  ANGGQNGTVQEIMIPAGKAG 246
             + G  G       P G+AG
Sbjct: 1546 GSSGPTG-------PKGEAG 1558



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 29/71 (40%), Positives = 30/71 (42%), Gaps = 10/71 (14%)

Query: 6    TGGPPP----GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPS 59
            TG P P    GP  P G  G  G  G   PPGPPG      G PG  G  G  G  G   
Sbjct: 990  TGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQ----GLPGLAGKEGTKGDPGPAG 1045

Query: 60   QPPGGGGPGIR 70
             P   G PG+R
Sbjct: 1046 LPGKDGPPGLR 1056



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 29/76 (38%), Positives = 29/76 (38%), Gaps = 15/76 (19%)

Query: 7   GGPPPGPPPPAG--GGGGAGGAGG-----------GPPPGPPGAGDRGGGGPGG--GGPG 51
           G  PPGP  P G  G  G  GA G           G    P   GD G  G  G  G PG
Sbjct: 776 GQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPG 835

Query: 52  GGSAGGPSQPPGGGGP 67
                GP  P G GGP
Sbjct: 836 PRGEDGPEGPKGRGGP 851



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 22/54 (40%), Positives = 22/54 (40%), Gaps = 12/54 (22%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
            PPGPP   G  G  G  G   P GP G      G PG  GP G        PPG
Sbjct: 1529 PPGPPGLPGPPGPKGAKGSSGPTGPKGE----AGHPGPPGPPG--------PPG 1570


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 94/333 (28%), Positives = 115/333 (34%), Gaps = 66/333 (19%)

Query: 396 GPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTG 455
           GPP PPG P  PP  +G  + QG   PPG                   G   +  N+  G
Sbjct: 49  GPPSPPGKPQGPPP-QGGNQPQGPPPPPGKPQ----------------GPPPQGGNKPQG 91

Query: 456 AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPM 515
                    PP G P       +G P Q D        K   P  P G  P GP P G  
Sbjct: 92  P--------PPPGKP-------QGPPPQGD--------KSRSPRSPPGK-PQGPPPQGGN 127

Query: 516 GPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAA 575
            P  P P   G P  PP  GG  P   PP G     PQ  PP   + S+++ +       
Sbjct: 128 QPQGPPP-PPGKPQGPPPQGGNKPQGPPPPG----KPQGPPPQGDNKSRSSRSPPGKPQG 182

Query: 576 WAAYYSHYYQQPP-------GPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYK- 627
                 +  Q PP       GP P     P  PP  G+P  PPP G +    A     K 
Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP 242

Query: 628 -----KIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYY 682
                + G QPQ P  PP +      +   K Q     G   G PP       ++ +   
Sbjct: 243 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPG 302

Query: 683 RQQA-------AYYGQTPGPGGPQPPPTQQGQQ 708
           + Q           G  P PG PQ PP Q G +
Sbjct: 303 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 335



 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 101/347 (29%), Positives = 122/347 (35%), Gaps = 102/347 (29%)

Query: 365 GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPG 424
           GP       GPP + ++ +R       S RS PPG P GP  PP G  + +G     PP 
Sbjct: 152 GPPPPGKPQGPPPQGDNKSR-------SSRS-PPGKPQGP--PPQGGNQPQGPP---PPP 198

Query: 425 GEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQI 484
           G+     P         +GG      N+  G         PP G P       +G P Q 
Sbjct: 199 GKPQGPPP---------QGG------NKPQGP--------PPPGKP-------QGPPPQG 228

Query: 485 DHAKQLIEEKIEGPLCPVGPGP-GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYP 543
           D+  Q        P  P GP P GG  P GP  P        G P  PP  GG  P   P
Sbjct: 229 DNKSQSARSP---PGKPQGPPPQGGNQPQGPPPP-------PGKPQGPPPQGGNKPQGPP 278

Query: 544 PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQ-----PPGPVPGPAPA- 597
           P G      + Q P P   SK+ ++ + P            Q      PPG   GP P  
Sbjct: 279 PPG------KPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 332

Query: 598 ---PAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKK 654
              P  PP  G+P  PPP G S    A           P +P  PPQQ+           
Sbjct: 333 GNKPQGPPPPGKPQGPPPQGGSKSRSA--------RSPPGKPQGPPQQEGNNP------- 377

Query: 655 QAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPP 701
                   GP  P G  P          + QA   GQ  GP  P+PP
Sbjct: 378 -------QGPPPPAGGNPQ---------QPQAPPAGQPQGP--PRPP 406



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 75/232 (32%), Positives = 84/232 (36%), Gaps = 46/232 (19%)

Query: 504 PGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAG----GPPPHQYPPQG---WGNTYPQWQP 556
           P  GG  P GP  P  PG     P G PP  G    GPPP    PQG    G   PQ  P
Sbjct: 40  PPQGGNKPQGPPSP--PGK----PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 93

Query: 557 P--APHDPSKAAAAAADPNAAWAAYYSHYYQ---QPPGPVP------GPAP----APAAP 601
           P   P  P      +  P +          Q   QP GP P      GP P     P  P
Sbjct: 94  PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 153

Query: 602 PAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQ---QPGAPPQQDYTKAWEEYYKKQAQV 658
           P  G+P  PPP G +    +     K  G  PQ   QP  PP            K Q   
Sbjct: 154 PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP--------GKPQGPP 205

Query: 659 ATGGG--PGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708
             GG    G PP  +P       +   Q A    ++P PG PQ PP Q G Q
Sbjct: 206 PQGGNKPQGPPPPGKPQGPPPQGDNKSQSA----RSP-PGKPQGPPPQGGNQ 252



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 59/210 (28%), Positives = 71/210 (33%), Gaps = 46/210 (21%)

Query: 519 NPGPFNQGPPGAPPHAG----GPPPHQYPPQG---WGNTYPQWQPPAPHDPSKAAAAAAD 571
           +P      P GAPP  G    GPP     PQG    G   PQ  PP P  P        +
Sbjct: 28  SPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 87

Query: 572 PNAAWAAYYSHYYQQPPGPVPGPAP------APAAPPAQGEPPQPPPTGQSDYTKAWEEY 625
                          PPG   GP P      +P +PP  G+P  PPP G           
Sbjct: 88  KPQG---------PPPPGKPQGPPPQGDKSRSPRSPP--GKPQGPPPQG----------- 125

Query: 626 YKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQ 685
               G QPQ P  PP +      +   K Q     G   G PP       ++ +   + Q
Sbjct: 126 ----GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQ 181

Query: 686 A-------AYYGQTPGPGGPQPPPTQQGQQ 708
                      G  P PG PQ PP Q G +
Sbjct: 182 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 211



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 24/57 (42%), Positives = 25/57 (43%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
           G  P GPPPP G   G    GG  P GPP  G   G  P GG     S   P +P G
Sbjct: 250 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQG 306



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 30/77 (38%), Positives = 30/77 (38%), Gaps = 16/77 (20%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGG-------GPGGGSAGGPS 59
           G  P GPPPP G   G    GG  P GPP  G   G  P GG        P G   G P 
Sbjct: 312 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQ 371

Query: 60  Q---------PPGGGGP 67
           Q         PP GG P
Sbjct: 372 QEGNNPQGPPPPAGGNP 388



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 29/68 (42%), Positives = 30/68 (44%), Gaps = 12/68 (17%)

Query: 8   GPPPGP-----PPPAGGGGGAGGAGGGPPPGPPGAGDRG------GGGPGGGGP-GGGSA 55
           GPPP P     PPP GG    G    G P GPP  GD+        G P G  P GG   
Sbjct: 70  GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 129

Query: 56  GGPSQPPG 63
            GP  PPG
Sbjct: 130 QGPPPPPG 137



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 23/57 (40%), Positives = 24/57 (42%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
           G  P GPPPP G   G    GG  P GPP  G   G  P G      S   P +P G
Sbjct: 126 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 9/69 (13%)

Query: 8   GPPPGPPPPAGGGGGAGGAGGGPPPGPP---GAGDRGGGGPGGGGPG------GGSAGGP 58
           G P GPPP  G    +  +  G P GPP   G   +G   P GG P        G   GP
Sbjct: 343 GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 402

Query: 59  SQPPGGGGP 67
            +PP GG P
Sbjct: 403 PRPPQGGRP 411



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 31/74 (41%), Positives = 31/74 (41%), Gaps = 17/74 (22%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGG----GPPP-----GPPGAGDRGG-------GGPGGGGP 50
           G  P GPPPP G   G    GG    GPPP     GPP  GD          G P G  P
Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP 247

Query: 51  -GGGSAGGPSQPPG 63
            GG    GP  PPG
Sbjct: 248 QGGNQPQGPPPPPG 261



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 28/66 (42%), Positives = 28/66 (42%), Gaps = 11/66 (16%)

Query: 9   PPPGPP---PPAGGGGGAGGAGGGPPPGPPGAGDRGG-------GGPGGGGP-GGGSAGG 57
           PPPG P   PP GG    G    G P GPP  GD          G P G  P GG    G
Sbjct: 134 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQG 193

Query: 58  PSQPPG 63
           P  PPG
Sbjct: 194 PPPPPG 199



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 43/130 (33%), Positives = 46/130 (35%), Gaps = 21/130 (16%)

Query: 2   SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPP-GAGDRGGGGPGGGGPGGGSAGGPSQ 60
           S  S  G P GPPP     GG    G  PPPG P G   +GG  P G  P     G P  
Sbjct: 296 SSRSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQG 347

Query: 61  PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNN---STPDFGFGGQKRQLEDGDQ 117
           PP  GG   R          AR    K  G      NN     P  G   Q+ Q     Q
Sbjct: 348 PPPQGGSKSRS---------ARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 398

Query: 118 PESKKLASQG 127
           P+      QG
Sbjct: 399 PQGPPRPPQG 408



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 30/81 (37%), Positives = 31/81 (38%), Gaps = 25/81 (30%)

Query: 8   GPPPGP-----PPPAGGGGGAGGAGGGPPPGPPGAGD------------------RGGGG 44
           GPPP P     PPP GG    G    G P GPP  GD                  +GG  
Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQ 190

Query: 45  PGGGGPGGGSAGGPSQPPGGG 65
           P G  P  G   GP  PP GG
Sbjct: 191 PQGPPPPPGKPQGP--PPQGG 209



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 30/81 (37%), Positives = 31/81 (38%), Gaps = 25/81 (30%)

Query: 8   GPPPGP-----PPPAGGGGGAGGAGGGPPPGPPGAGD------------------RGGGG 44
           GPPP P     PPP GG    G    G P GPP  GD                  +GG  
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ 252

Query: 45  PGGGGPGGGSAGGPSQPPGGG 65
           P G  P  G   GP  PP GG
Sbjct: 253 PQGPPPPPGKPQGP--PPQGG 271



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 25/60 (41%), Positives = 27/60 (45%), Gaps = 3/60 (5%)

Query: 7   GGPPPGPPP-PAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGG 65
           G PPPG P  P   GG    +   PP  P G   +GG  P G  P  G   GP  PP GG
Sbjct: 276 GPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGG 333



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 28/66 (42%), Positives = 29/66 (43%), Gaps = 11/66 (16%)

Query: 9   PPPGPP---PPAGGGGGAGGAGGGPPPGPP---GAGDRGGGGPGG--GGP---GGGSAGG 57
           PPPG P   PP GG    G    G P GPP   G+  R    P G   GP   GG    G
Sbjct: 258 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG 317

Query: 58  PSQPPG 63
           P  PPG
Sbjct: 318 PPPPPG 323



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/61 (39%), Positives = 25/61 (40%), Gaps = 7/61 (11%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGPPPGPP-------GAGDRGGGGPGGGGPGGGSAGGPS 59
           G  P GPP P G   G    GG  P GPP       G   +GG  P G  P G   G P 
Sbjct: 44  GNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 103

Query: 60  Q 60
           Q
Sbjct: 104 Q 104



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/62 (41%), Positives = 29/62 (46%), Gaps = 8/62 (12%)

Query: 7   GGPPPGP---PPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
           G PPPG    PPP G    +  +  G P GPP    +GG  P G  P  G   GP  PP 
Sbjct: 91  GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGP--PPQ 145

Query: 64  GG 65
           GG
Sbjct: 146 GG 147



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/60 (43%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 2   SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPP-GAGDRGGGGPGGGGPGGGSAGGPSQ 60
           S  S  G P GPPP     GG    G  PPPG P G   +GG  P G  P G   G P Q
Sbjct: 172 SSRSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 227



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/61 (42%), Positives = 26/61 (42%), Gaps = 6/61 (9%)

Query: 5   STGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGG 64
           S  G P GPPP     GG    G  PPPG P      GG    G P  G   GP  PP G
Sbjct: 237 SPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQG 290

Query: 65  G 65
           G
Sbjct: 291 G 291



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 26/60 (43%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 2   SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPG-PPGAGDRGGGGPGGGGPGGGSAGGPSQ 60
           S  S  G P GPPP     GG    G  PPPG P G   +GG  P G  P G   G P Q
Sbjct: 110 SPRSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 165



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 23/58 (39%), Positives = 25/58 (43%), Gaps = 5/58 (8%)

Query: 8  GPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGG 65
          G P G PP  G       +  G P GPP    +GG  P G  P  G   GP  PP GG
Sbjct: 34 GNPQGAPPQGGNKPQGPPSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGP--PPQGG 86



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 56/175 (32%), Positives = 63/175 (36%), Gaps = 45/175 (25%)

Query: 396 GPPGPPGGP-GMPPGGRGRGRGQGNWGPP------GGEMTFSI--PTHKCGLVIGRGGEN 446
           GPP PPG P G PP G  + +G    G P      GG  + S   P  K      +GG  
Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG-- 312

Query: 447 VKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE--KIEGP------ 498
               NQ  G         PP G P       +G P Q  +  Q      K +GP      
Sbjct: 313 ----NQPQGP-------PPPPGKP-------QGPPPQGGNKPQGPPPPGKPQGPPPQGGS 354

Query: 499 -----LCPVGPGPGGPGPAG--PMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQG 546
                  P G   G P   G  P GP  P   N   P APP AG P     PPQG
Sbjct: 355 KSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP-AGQPQGPPRPPQG 408


>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
          Length = 371

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 93/401 (23%), Positives = 158/401 (39%), Gaps = 90/401 (22%)

Query: 138 HPPPRTSMTEEYRVPDG---------------MVGLIIGRGGEQINKIQQDSGCKVQISP 182
           HP P+     E +V +G                VG IIG+ GE + K++++SG ++ IS 
Sbjct: 24  HPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINIS- 82

Query: 183 DSGGLPERSVSLTGAPESVQKAKMML-----DDIVSRGRGGPPGQFHDNANGGQNGTVQE 237
             G  PER V++TG  +++ KA  M+     +DI++     P           +      
Sbjct: 83  -EGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATS--------KPPVTLR 133

Query: 238 IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACE 297
           +++PA + G +IGKGG  IK+++E  G ++ +  D   N + ++ + I G P  + Q  +
Sbjct: 134 LVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN-STERAVTISGTPDAIIQCVK 192

Query: 298 MVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQ 357
            +  ++ E                  G  +P         +  +G     IQ        
Sbjct: 193 QICVVMLESPP--------------KGATIPYRPKPASTPVIFAGGQAYTIQ-------- 230

Query: 358 FKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--PGGR---- 411
                  G   I H    PD+       +  L Q      P PP G   P  PG +    
Sbjct: 231 -------GQYAIPH----PDQ-------LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLH 272

Query: 412 ---------GRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISR 462
                    G+  G  +  PP      +IP    G +IGR G  +  I Q +GA ++I+ 
Sbjct: 273 SSEEAQNLMGQSSGL-DASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIAN 331

Query: 463 QLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG 503
               + +   +   I G+P  I  A+ LI  ++   +  +G
Sbjct: 332 ATEGSSE---RQITITGTPANISLAQYLINARLTSEVTGMG 369



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 63/236 (26%), Positives = 99/236 (41%), Gaps = 52/236 (22%)

Query: 300 MDILRERDQGGFGDRNEYGSRIG-GGIDVPVPRH------SVGVVIGRSGEMIKKIQNDA 352
           +  L    Q  FG R E  S++  GG++V +          VG +IG+ GE +KK++ ++
Sbjct: 18  LSTLSHHPQPQFGRRME--SKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREES 75

Query: 353 GVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARII-----NDLLQSLRSGPPGPPGGPGMP 407
           G RI   +  G  PE+I  I GP D    A  +I      D++ S+ + P          
Sbjct: 76  GARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPAT-------- 125

Query: 408 PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPN 467
                          P   +   +P  +CG +IG+GG  +K I + TGA V+++  + PN
Sbjct: 126 -------------SKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN 172

Query: 468 GDPNFKLFIIRGSPQQ-IDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGP 522
                +   I G+P   I   KQ+    +E P            P G   P+ P P
Sbjct: 173 STE--RAVTISGTPDAIIQCVKQICVVMLESP------------PKGATIPYRPKP 214



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 32/105 (30%), Positives = 60/105 (57%), Gaps = 10/105 (9%)

Query: 105 FGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGG 164
           F G+K  L   +  E++ L  Q   + +       PP +  T E  +P+ ++G IIGR G
Sbjct: 264 FPGEKLPLHSSE--EAQNLMGQSSGLDAS------PPAS--THELTIPNDLIGCIIGRQG 313

Query: 165 EQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLD 209
            +IN+I+Q SG +++I+  + G  ER +++TG P ++  A+ +++
Sbjct: 314 TKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 358


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 194/731 (26%), Positives = 234/731 (32%), Gaps = 126/731 (17%)

Query: 15   PPAGGGGGAGGAGGGPPP----GPPGA-GDRGGGGPGGG-GPGGGSAG-GPSQPPGGGGP 67
            P A G  GA G  G P P    GP G  G RG  GP G  GP G S G GP  PPG  GP
Sbjct: 873  PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 932

Query: 68   GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQG 127
               +        +        G D          + GF G+      G       +  QG
Sbjct: 933  QGPQGPVGFPGPKGPP--GPPGKDGLPGHPGQRGETGFQGKT-----GPPGPGGVVGPQG 985

Query: 128  DSISSQLGPI----HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQ-QDSGCKVQISP 182
             +   + GPI    HP P     E+  +P G  G    +G      I  +D    ++  P
Sbjct: 986  PT--GETGPIGERGHPGPPGPPGEQ-GLP-GAAGKEGAKGDPGPQGISGKDGPAGLRGFP 1041

Query: 183  DSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPA 242
               GLP       GAP                G  GPPG        G  GT   I +P 
Sbjct: 1042 GERGLP----GAQGAPGLKG----------GEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1087

Query: 243  -----GKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKVQQAC 296
                 G  G    KG    K  Q  AG      +DG Q    +  P    G P +     
Sbjct: 1088 RPGPQGPPGPAGEKGAPGEKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKG 1141

Query: 297  EMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRI 356
            E    I     +G  GD+ E G     G+  PV    +    G  G      +   G+  
Sbjct: 1142 E----IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP-----RGQQGMFG 1192

Query: 357  QFKQDDGT-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPG 409
            Q K D+G        GP  +  + GPP        +          GP GPPG PG P G
Sbjct: 1193 Q-KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----------GPMGPPGPPG-PRG 1240

Query: 410  GRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGD 469
             +G     G  GPPG   +           +G  GE  +A N        +     P G+
Sbjct: 1241 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGG---PKGE 1289

Query: 470  PNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAG----PMGPFNPGPFNQ 525
                    RG   +            +GP    GP  G PGP G    P  P  PGP  Q
Sbjct: 1290 --------RGEKGEAGPPGAAGPPGAKGPPGDDGP-KGNPGPVGFPGDPGPPGEPGPAGQ 1340

Query: 526  GPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQ 585
               G      G P    PP   G   P   PP    P  AA A        A   +    
Sbjct: 1341 DGVGGDKGEDGDPGQPGPPGPSGEAGPP-GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1399

Query: 586  QP--PGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQ-PQQPGAPPQQ 642
             P   GPV GP      P  +G    P P G+     A        GQ  P  P  PP  
Sbjct: 1400 PPGKTGPV-GPQGPAGKPGPEGLRGIPGPVGEQGLPGA-------AGQDGPPGPMGPPGL 1451

Query: 643  DYTKAWEEYYKKQAQVATGGGPG-----APPGSQPDYSAAWAEYYRQQ--AAYYGQTPGP 695
               K               G PG      PPG Q +         +    A   G  PGP
Sbjct: 1452 PGLKG------DPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1505

Query: 696  GGPQPPPTQQG 706
             GP  PP   G
Sbjct: 1506 AGPLGPPGPPG 1516



 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 180/661 (27%), Positives = 222/661 (33%), Gaps = 109/661 (16%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSAGGPSQPPG-GG 65
            PPGP    G  G  G  GG   PG PGA GDRG  G  G  G  G     GP  PPG  G
Sbjct: 581  PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 640

Query: 66   GPGIRKDAFADAVQRARQIAAKIG-----GDAATTVNNSTPDF----GFGGQKRQLEDGD 116
              G+R +   D     R +  + G     G   T      P      G  G K  +  G 
Sbjct: 641  DDGMRGE---DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM--GP 695

Query: 117  QPESKKLASQGD----SISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQ 172
            Q E      QG+     +    GPI PP       +     G+ GL    G       + 
Sbjct: 696  QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK----PGLAGLPGADGPPGHPGKEG 751

Query: 173  DSGCKVQISPDSGGLPERSVSLTGAPESVQKA---KMMLDDIVSRGRGGPPGQFHDNANG 229
             SG K  + P     P+  +   G P  V+ A   + +      +G  G PG   D    
Sbjct: 752  QSGEKGALGPPG---PQGPIGYPG-PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLK 807

Query: 230  GQNGTVQEI--------MIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK 281
            G  G V +I          P G+AG     G       + + GV  +    G Q      
Sbjct: 808  GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----- 862

Query: 282  PLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRS 341
            P    G P                   G  G   E G+R  G    P PR   G    R 
Sbjct: 863  PKGSTGFP-------------------GFPGANGEKGAR--GVAGKPGPRGQRGPTGPRG 901

Query: 342  GEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPP 401
                +      G +     D   GP       GP                    GPPGPP
Sbjct: 902  SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG----------PKGPPGPP 951

Query: 402  GGPGMP--PGGRGRGRGQGNWGP--PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAF 457
            G  G+P  PG RG    QG  GP  PGG +    PT + G +  RG         + G  
Sbjct: 952  GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 1011

Query: 458  VEISRQLPPNGDPNFKLFI-------IRGSPQQ-----IDHAKQLI-EEKIEGPLCPVG- 503
                ++    GDP  +          +RG P +        A  L   E  +GP  PVG 
Sbjct: 1012 GAAGKE-GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1070

Query: 504  PGP-GGPGPAGPMG-PFNPGPFNQGPPGAPPHAGGPPPHQYP--PQGWGNTYPQWQPPAP 559
            PG  G  G AGP+G P  PGP  QGPPG P    G P  + P  P G          P P
Sbjct: 1071 PGERGSAGTAGPIGLPGRPGP--QGPPG-PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1127

Query: 560  HDPSKAAAAAADPN-----AAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTG 614
              P+ +     D           +        PPGP PG      AP   G   +P P G
Sbjct: 1128 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP-PGLQGPVGAPGIAGGDGEPGPRG 1186

Query: 615  Q 615
            Q
Sbjct: 1187 Q 1187



 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 192/769 (24%), Positives = 250/769 (32%), Gaps = 154/769 (20%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGG------- 64
            GPP PAG  G  G  G   P GPPG  D G  GP G  PG   A G   PPG        
Sbjct: 454  GPPGPAGPAGIMGPPGLQGPTGPPG--DPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFR 510

Query: 65   -GGPGIR------KDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQ 117
             GG G +      ++A A A+ +  +IA +             P  G G    + E GD 
Sbjct: 511  YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 570

Query: 118  PESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCK 177
                    QG       GP   P +           G  G   GRG      +  + G K
Sbjct: 571  GPQGPRGVQGPP-----GPTGKPGKR----------GRPGADGGRG------MPGEPGAK 609

Query: 178  VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQE 237
                 D  GLP       G P               RG  GPPG   D+   G++G +  
Sbjct: 610  GDRGFD--GLP-------GLPGDKGHRG-------ERGPQGPPGPPGDDGMRGEDGEIGP 653

Query: 238  IMIP--AGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK-------------- 281
              +P  AG  GL+  +G          AGV       G+     +               
Sbjct: 654  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 713

Query: 282  --PLRIIGDPYKVQQACEMVMDILRERD--QGGFGDRNEYGSRIGGGIDVPVPRHSVGVV 337
              P   IG P +     +  +  L   D   G  G   + G +  G +  P P+  +G  
Sbjct: 714  PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK--GALGPPGPQGPIGYP 771

Query: 338  IGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGP 397
              R  +    ++   G + +  +D   G +    + G  DR E     +  +      GP
Sbjct: 772  GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG--DRGE-----VGQIGPRGEDGP 824

Query: 398  PGPPG--GPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKAI 450
             GP G  GP   PG  G+   +G  G PG     G       T   G     G +  + +
Sbjct: 825  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 884

Query: 451  NQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPG 510
              + G       Q  P G         RGS        +   +   G   P GP PG  G
Sbjct: 885  AGKPGP----RGQRGPTGP--------RGSRGARGPTGKPGPKGTSGGDGPPGP-PGERG 931

Query: 511  PAGPMGPFN-PGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQ--PPAPHDPSKAAA 567
            P GP GP   PGP  +GPPG PP   G P H   P   G T  Q +  PP P        
Sbjct: 932  PQGPQGPVGFPGP--KGPPG-PPGKDGLPGH---PGQRGETGFQGKTGPPGPG----GVV 981

Query: 568  AAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSD---------- 617
                P           +  PPGP PG    P A   +G    P P G S           
Sbjct: 982  GPQGPTGETGPIGERGHPGPPGP-PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 1040

Query: 618  -----YTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG--------GP 664
                    A      K G+ PQ P  P              ++    T G        GP
Sbjct: 1041 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSP---------GERGSAGTAGPIGLPGRPGP 1091

Query: 665  GAPPGSQPDYSAAWAEYYRQQAAYYGQT-----PGPGGPQPPPTQQGQQ 708
              PPG   +  A   +  +  A   G       PGP GP   P + G +
Sbjct: 1092 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1140



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 182/691 (26%), Positives = 226/691 (32%), Gaps = 113/691 (16%)

Query: 5    STGGPPPGPP---PPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGGPGG--GGPGG 52
            S G  PPGPP    P G  G  G  G   PPGPPG        G RG  G  G  G PG 
Sbjct: 918  SGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP 977

Query: 53   GSAGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQ 111
            G   GP  P G  GP G R           + +    G + A          G  G+   
Sbjct: 978  GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA---KGDPGPQGISGKDGP 1034

Query: 112  LEDGDQPESKKL--ASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLI--IGRGGEQ- 166
                  P  + L  A     +    GP  PP       E R   G  G I   GR G Q 
Sbjct: 1035 AGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE-RGSAGTAGPIGLPGRPGPQG 1093

Query: 167  INKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDN 226
                  + G   +  P      +      G P     A    +D   +G  G PGQ    
Sbjct: 1094 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED-GDKGEIGEPGQKGSK 1152

Query: 227  ANGGQNGT--VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPL 283
             + G+NG      +  P G  G+  G G    +  Q   G K     +G++       P+
Sbjct: 1153 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG---DEGARGFPGPPGPI 1209

Query: 284  RIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSVGVV--IGR 340
             + G P    +  E   D+      G  G R   G     G D P  P  SVG V  +G 
Sbjct: 1210 GLQGLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGP---NGADGPQGPPGSVGSVGGVGE 1265

Query: 341  SGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPP-DRCEHAARIINDLLQSLRSGPPG 399
             GE       +AG           GP   A + GP  +R E              +GPPG
Sbjct: 1266 KGE-----PGEAG---------NPGPPGEAGVGGPKGERGEKG-----------EAGPPG 1300

Query: 400  PPGGPGM--PPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQTG 455
              G PG   PPG  G     G  G PG  G      P  + G+   +G +         G
Sbjct: 1301 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1360

Query: 456  AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPM 515
                 S +  P G P       RG P       +  E+  +G     GP PG  GP GP 
Sbjct: 1361 P----SGEAGPPGPPG-----KRGPPGAAGAEGRQGEKGAKGEAGAEGP-PGKTGPVGPQ 1410

Query: 516  GPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNA 574
            GP   PGP  +G  G P    GP   Q  P   G    Q  PP P  P        DP +
Sbjct: 1411 GPAGKPGP--EGLRGIP----GPVGEQGLPGAAG----QDGPPGPMGPPGLPGLKGDPGS 1460

Query: 575  AWAAYYSHYYQ--QPPGP-----------------------VPGPAPAPAAPPAQGEP-P 608
                 +        PPG                        +PGPA     P   G P P
Sbjct: 1461 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP 1520

Query: 609  QPPPTGQSDYTKAWEEYYKKIGQQPQQPGAP 639
            Q P   +     A ++    +   P  PG P
Sbjct: 1521 QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1551



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 96/337 (28%), Positives = 116/337 (34%), Gaps = 67/337 (19%)

Query: 396  GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447
            GP GP G PG          PG +G    +G  GPPG       P    G+    GG+  
Sbjct: 1126 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP-GLQGPVGAPGIA---GGDGE 1181

Query: 448  KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE-GPLCPVGPGP 506
                 Q G F +        GD   + F     P  +        EK E G + P+GP P
Sbjct: 1182 PGPRGQQGMFGQ-------KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP-P 1233

Query: 507  GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPA--PHDPSK 564
            G PGP GP GP N     QGPPG+    GG      P +  GN  P  +     P     
Sbjct: 1234 GPPGPRGPQGP-NGADGPQGPPGSVGSVGGVGEKGEPGEA-GNPGPPGEAGVGGPKGERG 1291

Query: 565  AAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAPPAQGEPPQPPPTGQSDYT 619
                A  P AA         + PPG       PGP   P  P   G P +P P GQ    
Sbjct: 1292 EKGEAGPPGAAGPPGA----KGPPGDDGPKGNPGPVGFPGDP---GPPGEPGPAGQDGVG 1344

Query: 620  KAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWA 679
                E        P QPG P                       GP  PPG +    AA A
Sbjct: 1345 GDKGE-----DGDPGQPGPPGPSGEA-----------------GPPGPPGKRGPPGAAGA 1382

Query: 680  EYYRQQAAYYGQT--------PGPGGPQPPPTQQGQQ 708
            E  + +    G+          GP GPQ P  + G +
Sbjct: 1383 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE 1419



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 90/355 (25%), Positives = 122/355 (34%), Gaps = 70/355 (19%)

Query: 396  GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447
            GP G PG  G+P        PG  G+   +G  GPPG +     P  + G+   +G + V
Sbjct: 727  GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPR-GV---KGADGV 782

Query: 448  KAINQQTGAFVEISRQLPPNGDPNFKLFI-IRGSPQQIDHAKQLIEEKIEGPLCPVGPGP 506
            + +    G   E       +G P FK  + ++G   ++       E+  EGP    GP  
Sbjct: 783  RGLKGSKGEKGE-------DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP-T 834

Query: 507  GGPGPAGPMG-------PFNPG-PFNQGPPGAPPHAGGP----------------PPHQY 542
            G PGP+G  G       P  PG P  QGP G+    G P                P  Q 
Sbjct: 835  GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 894

Query: 543  PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV--PGPAPAPAA 600
             P G   +     P     P   +     P            Q P GPV  PGP   P  
Sbjct: 895  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG----ERGPQGPQGPVGFPGPKGPPGP 950

Query: 601  PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT 660
            P   G P  P   G++ +               Q    PP        +    +   +  
Sbjct: 951  PGKDGLPGHPGQRGETGF---------------QGKTGPPGPGGVVGPQGPTGETGPIGE 995

Query: 661  GG--GPGAPPGSQPDYSAAWAEYYRQQAAYYGQT--PGPGGPQPPPTQQGQQQAQ 711
             G  GP  PPG Q    AA  E  +      G +   GP G +  P ++G   AQ
Sbjct: 996  RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 1050



 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 68/235 (28%), Positives = 85/235 (36%), Gaps = 62/235 (26%)

Query: 495 IEGPLCPVGPGP--GGPGPAGPMGPFNPG-PFNQGPPGAPPHAG-----GPP------PH 540
           +EGP  P GP    G PG  GP GP  PG P ++GPPG P   G     GPP      P 
Sbjct: 452 VEGPPGPAGPAGIMGPPGLQGPTGP--PGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPF 509

Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPA 595
           +Y   G            P   ++ A A A    A  A      + PPGP+     PGP 
Sbjct: 510 RYGGDG---------SKGPTISAQEAQAQAILQQARIAL-----RGPPGPMGLTGRPGPV 555

Query: 596 PAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQ 655
             P +  A+GE   P P G                Q P  P   P             K+
Sbjct: 556 GGPGSSGAKGESGDPGPQGPRGV------------QGPPGPTGKP------------GKR 591

Query: 656 AQVATGGGPGAP--PGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708
            +    GG G P  PG++ D              + G+  GP GP  PP   G +
Sbjct: 592 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER-GPQGPPGPPGDDGMR 645



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 87/325 (26%), Positives = 110/325 (33%), Gaps = 55/325 (16%)

Query: 393 LRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGG-ENVKA 449
           L  GPPGP G  G+  PPG       QG  GPPG       P        GR G      
Sbjct: 451 LVEGPPGPAGPAGIMGPPGL------QGPTGPPGDPGDRGPP--------GRPGLPGADG 496

Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG----PG 505
           +    G  + +  +   +G    K   I     Q     Q     + GP  P+G    PG
Sbjct: 497 LPGPPGTMLMLPFRYGGDGS---KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG 553

Query: 506 P-GGPGPAGPMGPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPS 563
           P GGPG +G  G   +PGP  QGP G      GPP     P   G          P +P 
Sbjct: 554 PVGGPGSSGAKGESGDPGP--QGPRGVQ----GPPGPTGKPGKRGRPGADGGRGMPGEPG 607

Query: 564 KAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWE 623
                  D          H  ++ P   PGP   P     +GE  +  P G        E
Sbjct: 608 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGP---PGDDGMRGEDGEIGPRGLPG-----E 659

Query: 624 EYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYR 683
              + +      PGAP Q       +     +  +   G PG PPG Q +          
Sbjct: 660 AGPRGLLGPRGTPGAPGQPGMAGV-DGPPGPKGNMGPQGEPG-PPGQQGNPGPQ------ 711

Query: 684 QQAAYYGQTPGPGGPQPPPTQQGQQ 708
                    PGP GP  PP ++G Q
Sbjct: 712 -------GLPGPQGPIGPPGEKGPQ 729



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 27/61 (44%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGGGGP 67
            G P   G GG  G AG   PPGPPG     G  G  G  GP G  G +G P  P   G P
Sbjct: 1492 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1551

Query: 68   G 68
            G
Sbjct: 1552 G 1552



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 11/78 (14%)

Query: 3    DYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGA-------GDRGGGGPGG--GGPGGG 53
            D    G P  P PP G  G AG  G     GPPGA       G++G  G  G  G PG  
Sbjct: 1346 DKGEDGDPGQPGPP-GPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1404

Query: 54   SAGGPSQPPGGGGP-GIR 70
               GP  P G  GP G+R
Sbjct: 1405 GPVGPQGPAGKPGPEGLR 1422



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 53/169 (31%), Positives = 65/169 (38%), Gaps = 37/169 (21%)

Query: 8   GPPPGPPPPA--GGGGGAGGAGGGPPPGPPG-AGDRG----GGGPGGGGPGG-----GSA 55
           GP   P PP   G  G  G  G   P GPPG  G +G     G PG  GP G     G +
Sbjct: 694 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 753

Query: 56  G-----GPSQPPGG-GGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQK 109
           G     GP  P G  G PG R    AD V+  +    + G D            GF G K
Sbjct: 754 GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED------------GFPGFK 801

Query: 110 RQLE-DGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVG 157
             +   GD+ E  ++  +G+      GP  P  R   T +   P G  G
Sbjct: 802 GDMGLKGDRGEVGQIGPRGED-----GPEGPKGRAGPTGD-PGPSGQAG 844



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 20/44 (45%), Positives = 20/44 (45%), Gaps = 3/44 (6%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRG-GGGPGGGGPGG 52
            PPGPP   G  G  G  G   P G    GD G  G PG  GP G
Sbjct: 1511 PPGPPGLPGPQGPKGNKGSTGPAGQ--KGDSGLPGPPGSPGPPG 1552


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 194/731 (26%), Positives = 234/731 (32%), Gaps = 126/731 (17%)

Query: 15   PPAGGGGGAGGAGGGPPP----GPPGA-GDRGGGGPGGG-GPGGGSAG-GPSQPPGGGGP 67
            P A G  GA G  G P P    GP G  G RG  GP G  GP G S G GP  PPG  GP
Sbjct: 822  PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 881

Query: 68   GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQG 127
               +        +        G D          + GF G+      G       +  QG
Sbjct: 882  QGPQGPVGFPGPKGPP--GPPGKDGLPGHPGQRGETGFQGKT-----GPPGPGGVVGPQG 934

Query: 128  DSISSQLGPI----HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQ-QDSGCKVQISP 182
             +   + GPI    HP P     E+  +P G  G    +G      I  +D    ++  P
Sbjct: 935  PT--GETGPIGERGHPGPPGPPGEQ-GLP-GAAGKEGAKGDPGPQGISGKDGPAGLRGFP 990

Query: 183  DSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPA 242
               GLP       GAP                G  GPPG        G  GT   I +P 
Sbjct: 991  GERGLP----GAQGAPGLKG----------GEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1036

Query: 243  -----GKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKVQQAC 296
                 G  G    KG    K  Q  AG      +DG Q    +  P    G P +     
Sbjct: 1037 RPGPQGPPGPAGEKGAPGEKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKG 1090

Query: 297  EMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRI 356
            E    I     +G  GD+ E G     G+  PV    +    G  G      +   G+  
Sbjct: 1091 E----IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP-----RGQQGMFG 1141

Query: 357  QFKQDDGT-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPG 409
            Q K D+G        GP  +  + GPP        +          GP GPPG PG P G
Sbjct: 1142 Q-KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----------GPMGPPGPPG-PRG 1189

Query: 410  GRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGD 469
             +G     G  GPPG   +           +G  GE  +A N        +     P G+
Sbjct: 1190 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGG---PKGE 1238

Query: 470  PNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAG----PMGPFNPGPFNQ 525
                    RG   +            +GP    GP  G PGP G    P  P  PGP  Q
Sbjct: 1239 --------RGEKGEAGPPGAAGPPGAKGPPGDDGP-KGNPGPVGFPGDPGPPGEPGPAGQ 1289

Query: 526  GPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQ 585
               G      G P    PP   G   P   PP    P  AA A        A   +    
Sbjct: 1290 DGVGGDKGEDGDPGQPGPPGPSGEAGPP-GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1348

Query: 586  QP--PGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQ-PQQPGAPPQQ 642
             P   GPV GP      P  +G    P P G+     A        GQ  P  P  PP  
Sbjct: 1349 PPGKTGPV-GPQGPAGKPGPEGLRGIPGPVGEQGLPGA-------AGQDGPPGPMGPPGL 1400

Query: 643  DYTKAWEEYYKKQAQVATGGGPG-----APPGSQPDYSAAWAEYYRQQ--AAYYGQTPGP 695
               K               G PG      PPG Q +         +    A   G  PGP
Sbjct: 1401 PGLKG------DPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1454

Query: 696  GGPQPPPTQQG 706
             GP  PP   G
Sbjct: 1455 AGPLGPPGPPG 1465



 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 180/661 (27%), Positives = 222/661 (33%), Gaps = 109/661 (16%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSAGGPSQPPG-GG 65
            PPGP    G  G  G  GG   PG PGA GDRG  G  G  G  G     GP  PPG  G
Sbjct: 530  PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 589

Query: 66   GPGIRKDAFADAVQRARQIAAKIG-----GDAATTVNNSTPDF----GFGGQKRQLEDGD 116
              G+R +   D     R +  + G     G   T      P      G  G K  +  G 
Sbjct: 590  DDGMRGE---DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM--GP 644

Query: 117  QPESKKLASQGD----SISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQ 172
            Q E      QG+     +    GPI PP       +     G+ GL    G       + 
Sbjct: 645  QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK----PGLAGLPGADGPPGHPGKEG 700

Query: 173  DSGCKVQISPDSGGLPERSVSLTGAPESVQKA---KMMLDDIVSRGRGGPPGQFHDNANG 229
             SG K  + P     P+  +   G P  V+ A   + +      +G  G PG   D    
Sbjct: 701  QSGEKGALGPPG---PQGPIGYPG-PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLK 756

Query: 230  GQNGTVQEI--------MIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK 281
            G  G V +I          P G+AG     G       + + GV  +    G Q      
Sbjct: 757  GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----- 811

Query: 282  PLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRS 341
            P    G P                   G  G   E G+R  G    P PR   G    R 
Sbjct: 812  PKGSTGFP-------------------GFPGANGEKGAR--GVAGKPGPRGQRGPTGPRG 850

Query: 342  GEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPP 401
                +      G +     D   GP       GP                    GPPGPP
Sbjct: 851  SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG----------PKGPPGPP 900

Query: 402  GGPGMP--PGGRGRGRGQGNWGP--PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAF 457
            G  G+P  PG RG    QG  GP  PGG +    PT + G +  RG         + G  
Sbjct: 901  GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 960

Query: 458  VEISRQLPPNGDPNFKLFI-------IRGSPQQ-----IDHAKQLI-EEKIEGPLCPVG- 503
                ++    GDP  +          +RG P +        A  L   E  +GP  PVG 
Sbjct: 961  GAAGKE-GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1019

Query: 504  PGP-GGPGPAGPMG-PFNPGPFNQGPPGAPPHAGGPPPHQYP--PQGWGNTYPQWQPPAP 559
            PG  G  G AGP+G P  PGP  QGPPG P    G P  + P  P G          P P
Sbjct: 1020 PGERGSAGTAGPIGLPGRPGP--QGPPG-PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1076

Query: 560  HDPSKAAAAAADPN-----AAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTG 614
              P+ +     D           +        PPGP PG      AP   G   +P P G
Sbjct: 1077 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP-PGLQGPVGAPGIAGGDGEPGPRG 1135

Query: 615  Q 615
            Q
Sbjct: 1136 Q 1136



 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 192/769 (24%), Positives = 250/769 (32%), Gaps = 154/769 (20%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGG------- 64
            GPP PAG  G  G  G   P GPPG  D G  GP G  PG   A G   PPG        
Sbjct: 403  GPPGPAGPAGIMGPPGLQGPTGPPG--DPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFR 459

Query: 65   -GGPGIR------KDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQ 117
             GG G +      ++A A A+ +  +IA +             P  G G    + E GD 
Sbjct: 460  YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 519

Query: 118  PESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCK 177
                    QG       GP   P +           G  G   GRG      +  + G K
Sbjct: 520  GPQGPRGVQGPP-----GPTGKPGKR----------GRPGADGGRG------MPGEPGAK 558

Query: 178  VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQE 237
                 D  GLP       G P               RG  GPPG   D+   G++G +  
Sbjct: 559  GDRGFD--GLP-------GLPGDKGHRG-------ERGPQGPPGPPGDDGMRGEDGEIGP 602

Query: 238  IMIP--AGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK-------------- 281
              +P  AG  GL+  +G          AGV       G+     +               
Sbjct: 603  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 662

Query: 282  --PLRIIGDPYKVQQACEMVMDILRERD--QGGFGDRNEYGSRIGGGIDVPVPRHSVGVV 337
              P   IG P +     +  +  L   D   G  G   + G +  G +  P P+  +G  
Sbjct: 663  PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK--GALGPPGPQGPIGYP 720

Query: 338  IGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGP 397
              R  +    ++   G + +  +D   G +    + G  DR E     +  +      GP
Sbjct: 721  GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG--DRGE-----VGQIGPRGEDGP 773

Query: 398  PGPPG--GPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKAI 450
             GP G  GP   PG  G+   +G  G PG     G       T   G     G +  + +
Sbjct: 774  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 833

Query: 451  NQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPG 510
              + G       Q  P G         RGS        +   +   G   P GP PG  G
Sbjct: 834  AGKPGP----RGQRGPTGP--------RGSRGARGPTGKPGPKGTSGGDGPPGP-PGERG 880

Query: 511  PAGPMGPFN-PGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQ--PPAPHDPSKAAA 567
            P GP GP   PGP  +GPPG PP   G P H   P   G T  Q +  PP P        
Sbjct: 881  PQGPQGPVGFPGP--KGPPG-PPGKDGLPGH---PGQRGETGFQGKTGPPGPG----GVV 930

Query: 568  AAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSD---------- 617
                P           +  PPGP PG    P A   +G    P P G S           
Sbjct: 931  GPQGPTGETGPIGERGHPGPPGP-PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 989

Query: 618  -----YTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG--------GP 664
                    A      K G+ PQ P  P              ++    T G        GP
Sbjct: 990  PGERGLPGAQGAPGLKGGEGPQGPPGPVGSP---------GERGSAGTAGPIGLPGRPGP 1040

Query: 665  GAPPGSQPDYSAAWAEYYRQQAAYYGQT-----PGPGGPQPPPTQQGQQ 708
              PPG   +  A   +  +  A   G       PGP GP   P + G +
Sbjct: 1041 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 182/691 (26%), Positives = 226/691 (32%), Gaps = 113/691 (16%)

Query: 5    STGGPPPGPP---PPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGGPGG--GGPGG 52
            S G  PPGPP    P G  G  G  G   PPGPPG        G RG  G  G  G PG 
Sbjct: 867  SGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP 926

Query: 53   GSAGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQ 111
            G   GP  P G  GP G R           + +    G + A          G  G+   
Sbjct: 927  GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA---KGDPGPQGISGKDGP 983

Query: 112  LEDGDQPESKKL--ASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLI--IGRGGEQ- 166
                  P  + L  A     +    GP  PP       E R   G  G I   GR G Q 
Sbjct: 984  AGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE-RGSAGTAGPIGLPGRPGPQG 1042

Query: 167  INKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDN 226
                  + G   +  P      +      G P     A    +D   +G  G PGQ    
Sbjct: 1043 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED-GDKGEIGEPGQKGSK 1101

Query: 227  ANGGQNGT--VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPL 283
             + G+NG      +  P G  G+  G G    +  Q   G K     +G++       P+
Sbjct: 1102 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG---DEGARGFPGPPGPI 1158

Query: 284  RIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSVGVV--IGR 340
             + G P    +  E   D+      G  G R   G     G D P  P  SVG V  +G 
Sbjct: 1159 GLQGLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGP---NGADGPQGPPGSVGSVGGVGE 1214

Query: 341  SGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPP-DRCEHAARIINDLLQSLRSGPPG 399
             GE       +AG           GP   A + GP  +R E              +GPPG
Sbjct: 1215 KGE-----PGEAG---------NPGPPGEAGVGGPKGERGEKG-----------EAGPPG 1249

Query: 400  PPGGPGM--PPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQTG 455
              G PG   PPG  G     G  G PG  G      P  + G+   +G +         G
Sbjct: 1250 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309

Query: 456  AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPM 515
                 S +  P G P       RG P       +  E+  +G     GP PG  GP GP 
Sbjct: 1310 P----SGEAGPPGPPG-----KRGPPGAAGAEGRQGEKGAKGEAGAEGP-PGKTGPVGPQ 1359

Query: 516  GPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNA 574
            GP   PGP  +G  G P    GP   Q  P   G    Q  PP P  P        DP +
Sbjct: 1360 GPAGKPGP--EGLRGIP----GPVGEQGLPGAAG----QDGPPGPMGPPGLPGLKGDPGS 1409

Query: 575  AWAAYYSHYYQ--QPPGP-----------------------VPGPAPAPAAPPAQGEP-P 608
                 +        PPG                        +PGPA     P   G P P
Sbjct: 1410 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP 1469

Query: 609  QPPPTGQSDYTKAWEEYYKKIGQQPQQPGAP 639
            Q P   +     A ++    +   P  PG P
Sbjct: 1470 QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1500



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 96/337 (28%), Positives = 116/337 (34%), Gaps = 67/337 (19%)

Query: 396  GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447
            GP GP G PG          PG +G    +G  GPPG       P    G+    GG+  
Sbjct: 1075 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP-GLQGPVGAPGIA---GGDGE 1130

Query: 448  KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE-GPLCPVGPGP 506
                 Q G F +        GD   + F     P  +        EK E G + P+GP P
Sbjct: 1131 PGPRGQQGMFGQ-------KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP-P 1182

Query: 507  GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPA--PHDPSK 564
            G PGP GP GP N     QGPPG+    GG      P +  GN  P  +     P     
Sbjct: 1183 GPPGPRGPQGP-NGADGPQGPPGSVGSVGGVGEKGEPGEA-GNPGPPGEAGVGGPKGERG 1240

Query: 565  AAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAPPAQGEPPQPPPTGQSDYT 619
                A  P AA         + PPG       PGP   P  P   G P +P P GQ    
Sbjct: 1241 EKGEAGPPGAAGPPGA----KGPPGDDGPKGNPGPVGFPGDP---GPPGEPGPAGQDGVG 1293

Query: 620  KAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWA 679
                E        P QPG P                       GP  PPG +    AA A
Sbjct: 1294 GDKGE-----DGDPGQPGPPGPSGEA-----------------GPPGPPGKRGPPGAAGA 1331

Query: 680  EYYRQQAAYYGQT--------PGPGGPQPPPTQQGQQ 708
            E  + +    G+          GP GPQ P  + G +
Sbjct: 1332 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE 1368



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 90/355 (25%), Positives = 122/355 (34%), Gaps = 70/355 (19%)

Query: 396 GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447
           GP G PG  G+P        PG  G+   +G  GPPG +     P  + G+   +G + V
Sbjct: 676 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPR-GV---KGADGV 731

Query: 448 KAINQQTGAFVEISRQLPPNGDPNFKLFI-IRGSPQQIDHAKQLIEEKIEGPLCPVGPGP 506
           + +    G   E       +G P FK  + ++G   ++       E+  EGP    GP  
Sbjct: 732 RGLKGSKGEKGE-------DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP-T 783

Query: 507 GGPGPAGPMG-------PFNPG-PFNQGPPGAPPHAGGP----------------PPHQY 542
           G PGP+G  G       P  PG P  QGP G+    G P                P  Q 
Sbjct: 784 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 843

Query: 543 PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV--PGPAPAPAA 600
            P G   +     P     P   +     P            Q P GPV  PGP   P  
Sbjct: 844 GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG----ERGPQGPQGPVGFPGPKGPPGP 899

Query: 601 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT 660
           P   G P  P   G++ +               Q    PP        +    +   +  
Sbjct: 900 PGKDGLPGHPGQRGETGF---------------QGKTGPPGPGGVVGPQGPTGETGPIGE 944

Query: 661 GG--GPGAPPGSQPDYSAAWAEYYRQQAAYYGQT--PGPGGPQPPPTQQGQQQAQ 711
            G  GP  PPG Q    AA  E  +      G +   GP G +  P ++G   AQ
Sbjct: 945 RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 999



 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 68/235 (28%), Positives = 85/235 (36%), Gaps = 62/235 (26%)

Query: 495 IEGPLCPVGPGP--GGPGPAGPMGPFNPG-PFNQGPPGAPPHAG-----GPP------PH 540
           +EGP  P GP    G PG  GP GP  PG P ++GPPG P   G     GPP      P 
Sbjct: 401 VEGPPGPAGPAGIMGPPGLQGPTGP--PGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPF 458

Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPA 595
           +Y   G            P   ++ A A A    A  A      + PPGP+     PGP 
Sbjct: 459 RYGGDG---------SKGPTISAQEAQAQAILQQARIAL-----RGPPGPMGLTGRPGPV 504

Query: 596 PAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQ 655
             P +  A+GE   P P G                Q P  P   P             K+
Sbjct: 505 GGPGSSGAKGESGDPGPQGPRGV------------QGPPGPTGKP------------GKR 540

Query: 656 AQVATGGGPGAP--PGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708
            +    GG G P  PG++ D              + G+  GP GP  PP   G +
Sbjct: 541 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER-GPQGPPGPPGDDGMR 594



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 87/325 (26%), Positives = 110/325 (33%), Gaps = 55/325 (16%)

Query: 393 LRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGG-ENVKA 449
           L  GPPGP G  G+  PPG       QG  GPPG       P        GR G      
Sbjct: 400 LVEGPPGPAGPAGIMGPPGL------QGPTGPPGDPGDRGPP--------GRPGLPGADG 445

Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG----PG 505
           +    G  + +  +   +G    K   I     Q     Q     + GP  P+G    PG
Sbjct: 446 LPGPPGTMLMLPFRYGGDGS---KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG 502

Query: 506 P-GGPGPAGPMGPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPS 563
           P GGPG +G  G   +PGP  QGP G      GPP     P   G          P +P 
Sbjct: 503 PVGGPGSSGAKGESGDPGP--QGPRGVQ----GPPGPTGKPGKRGRPGADGGRGMPGEPG 556

Query: 564 KAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWE 623
                  D          H  ++ P   PGP   P     +GE  +  P G        E
Sbjct: 557 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGP---PGDDGMRGEDGEIGPRGLPG-----E 608

Query: 624 EYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYR 683
              + +      PGAP Q       +     +  +   G PG PPG Q +          
Sbjct: 609 AGPRGLLGPRGTPGAPGQPGMAGV-DGPPGPKGNMGPQGEPG-PPGQQGNPGPQ------ 660

Query: 684 QQAAYYGQTPGPGGPQPPPTQQGQQ 708
                    PGP GP  PP ++G Q
Sbjct: 661 -------GLPGPQGPIGPPGEKGPQ 678



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 27/61 (44%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGGGGP 67
            G P   G GG  G AG   PPGPPG     G  G  G  GP G  G +G P  P   G P
Sbjct: 1441 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1500

Query: 68   G 68
            G
Sbjct: 1501 G 1501



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 11/78 (14%)

Query: 3    DYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGA-------GDRGGGGPGG--GGPGGG 53
            D    G P  P PP G  G AG  G     GPPGA       G++G  G  G  G PG  
Sbjct: 1295 DKGEDGDPGQPGPP-GPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1353

Query: 54   SAGGPSQPPGGGGP-GIR 70
               GP  P G  GP G+R
Sbjct: 1354 GPVGPQGPAGKPGPEGLR 1371



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 53/169 (31%), Positives = 65/169 (38%), Gaps = 37/169 (21%)

Query: 8   GPPPGPPPPA--GGGGGAGGAGGGPPPGPPG-AGDRG----GGGPGGGGPGG-----GSA 55
           GP   P PP   G  G  G  G   P GPPG  G +G     G PG  GP G     G +
Sbjct: 643 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 702

Query: 56  G-----GPSQPPGG-GGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQK 109
           G     GP  P G  G PG R    AD V+  +    + G D            GF G K
Sbjct: 703 GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED------------GFPGFK 750

Query: 110 RQLE-DGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVG 157
             +   GD+ E  ++  +G+      GP  P  R   T +   P G  G
Sbjct: 751 GDMGLKGDRGEVGQIGPRGED-----GPEGPKGRAGPTGD-PGPSGQAG 793



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 20/44 (45%), Positives = 20/44 (45%), Gaps = 3/44 (6%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRG-GGGPGGGGPGG 52
            PPGPP   G  G  G  G   P G    GD G  G PG  GP G
Sbjct: 1460 PPGPPGLPGPQGPKGNKGSTGPAGQ--KGDSGLPGPPGSPGPPG 1501


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 194/731 (26%), Positives = 234/731 (32%), Gaps = 126/731 (17%)

Query: 15   PPAGGGGGAGGAGGGPPP----GPPGA-GDRGGGGPGGG-GPGGGSAG-GPSQPPGGGGP 67
            P A G  GA G  G P P    GP G  G RG  GP G  GP G S G GP  PPG  GP
Sbjct: 861  PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 920

Query: 68   GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQG 127
               +        +        G D          + GF G+      G       +  QG
Sbjct: 921  QGPQGPVGFPGPKGPP--GPPGKDGLPGHPGQRGETGFQGKT-----GPPGPGGVVGPQG 973

Query: 128  DSISSQLGPI----HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQ-QDSGCKVQISP 182
             +   + GPI    HP P     E+  +P G  G    +G      I  +D    ++  P
Sbjct: 974  PT--GETGPIGERGHPGPPGPPGEQ-GLP-GAAGKEGAKGDPGPQGISGKDGPAGLRGFP 1029

Query: 183  DSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPA 242
               GLP       GAP                G  GPPG        G  GT   I +P 
Sbjct: 1030 GERGLP----GAQGAPGLKG----------GEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1075

Query: 243  -----GKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKVQQAC 296
                 G  G    KG    K  Q  AG      +DG Q    +  P    G P +     
Sbjct: 1076 RPGPQGPPGPAGEKGAPGEKGPQGPAG------RDGVQGPVGLPGPAGPAGSPGEDGDKG 1129

Query: 297  EMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRI 356
            E    I     +G  GD+ E G     G+  PV    +    G  G      +   G+  
Sbjct: 1130 E----IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP-----RGQQGMFG 1180

Query: 357  QFKQDDGT-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPG 409
            Q K D+G        GP  +  + GPP        +          GP GPPG PG P G
Sbjct: 1181 Q-KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----------GPMGPPGPPG-PRG 1228

Query: 410  GRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGD 469
             +G     G  GPPG   +           +G  GE  +A N        +     P G+
Sbjct: 1229 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGG---PKGE 1277

Query: 470  PNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAG----PMGPFNPGPFNQ 525
                    RG   +            +GP    GP  G PGP G    P  P  PGP  Q
Sbjct: 1278 --------RGEKGEAGPPGAAGPPGAKGPPGDDGP-KGNPGPVGFPGDPGPPGEPGPAGQ 1328

Query: 526  GPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQ 585
               G      G P    PP   G   P   PP    P  AA A        A   +    
Sbjct: 1329 DGVGGDKGEDGDPGQPGPPGPSGEAGPP-GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1387

Query: 586  QP--PGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQ-PQQPGAPPQQ 642
             P   GPV GP      P  +G    P P G+     A        GQ  P  P  PP  
Sbjct: 1388 PPGKTGPV-GPQGPAGKPGPEGLRGIPGPVGEQGLPGA-------AGQDGPPGPMGPPGL 1439

Query: 643  DYTKAWEEYYKKQAQVATGGGPG-----APPGSQPDYSAAWAEYYRQQ--AAYYGQTPGP 695
               K               G PG      PPG Q +         +    A   G  PGP
Sbjct: 1440 PGLKG------DPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1493

Query: 696  GGPQPPPTQQG 706
             GP  PP   G
Sbjct: 1494 AGPLGPPGPPG 1504



 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 180/661 (27%), Positives = 222/661 (33%), Gaps = 109/661 (16%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSAGGPSQPPG-GG 65
            PPGP    G  G  G  GG   PG PGA GDRG  G  G  G  G     GP  PPG  G
Sbjct: 569  PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 628

Query: 66   GPGIRKDAFADAVQRARQIAAKIG-----GDAATTVNNSTPDF----GFGGQKRQLEDGD 116
              G+R +   D     R +  + G     G   T      P      G  G K  +  G 
Sbjct: 629  DDGMRGE---DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM--GP 683

Query: 117  QPESKKLASQGD----SISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQ 172
            Q E      QG+     +    GPI PP       +     G+ GL    G       + 
Sbjct: 684  QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK----PGLAGLPGADGPPGHPGKEG 739

Query: 173  DSGCKVQISPDSGGLPERSVSLTGAPESVQKA---KMMLDDIVSRGRGGPPGQFHDNANG 229
             SG K  + P     P+  +   G P  V+ A   + +      +G  G PG   D    
Sbjct: 740  QSGEKGALGPPG---PQGPIGYPG-PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLK 795

Query: 230  GQNGTVQEI--------MIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK 281
            G  G V +I          P G+AG     G       + + GV  +    G Q      
Sbjct: 796  GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----- 850

Query: 282  PLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRS 341
            P    G P                   G  G   E G+R  G    P PR   G    R 
Sbjct: 851  PKGSTGFP-------------------GFPGANGEKGAR--GVAGKPGPRGQRGPTGPRG 889

Query: 342  GEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPP 401
                +      G +     D   GP       GP                    GPPGPP
Sbjct: 890  SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG----------PKGPPGPP 939

Query: 402  GGPGMP--PGGRGRGRGQGNWGP--PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAF 457
            G  G+P  PG RG    QG  GP  PGG +    PT + G +  RG         + G  
Sbjct: 940  GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 999

Query: 458  VEISRQLPPNGDPNFKLFI-------IRGSPQQ-----IDHAKQLI-EEKIEGPLCPVG- 503
                ++    GDP  +          +RG P +        A  L   E  +GP  PVG 
Sbjct: 1000 GAAGKE-GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1058

Query: 504  PGP-GGPGPAGPMG-PFNPGPFNQGPPGAPPHAGGPPPHQYP--PQGWGNTYPQWQPPAP 559
            PG  G  G AGP+G P  PGP  QGPPG P    G P  + P  P G          P P
Sbjct: 1059 PGERGSAGTAGPIGLPGRPGP--QGPPG-PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1115

Query: 560  HDPSKAAAAAADPN-----AAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTG 614
              P+ +     D           +        PPGP PG      AP   G   +P P G
Sbjct: 1116 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP-PGLQGPVGAPGIAGGDGEPGPRG 1174

Query: 615  Q 615
            Q
Sbjct: 1175 Q 1175



 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 192/769 (24%), Positives = 250/769 (32%), Gaps = 154/769 (20%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGG------- 64
            GPP PAG  G  G  G   P GPPG  D G  GP G  PG   A G   PPG        
Sbjct: 442  GPPGPAGPAGIMGPPGLQGPTGPPG--DPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFR 498

Query: 65   -GGPGIR------KDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQ 117
             GG G +      ++A A A+ +  +IA +             P  G G    + E GD 
Sbjct: 499  YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 558

Query: 118  PESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCK 177
                    QG       GP   P +           G  G   GRG      +  + G K
Sbjct: 559  GPQGPRGVQGPP-----GPTGKPGKR----------GRPGADGGRG------MPGEPGAK 597

Query: 178  VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQE 237
                 D  GLP       G P               RG  GPPG   D+   G++G +  
Sbjct: 598  GDRGFD--GLP-------GLPGDKGHRG-------ERGPQGPPGPPGDDGMRGEDGEIGP 641

Query: 238  IMIP--AGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK-------------- 281
              +P  AG  GL+  +G          AGV       G+     +               
Sbjct: 642  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 701

Query: 282  --PLRIIGDPYKVQQACEMVMDILRERD--QGGFGDRNEYGSRIGGGIDVPVPRHSVGVV 337
              P   IG P +     +  +  L   D   G  G   + G +  G +  P P+  +G  
Sbjct: 702  PGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK--GALGPPGPQGPIGYP 759

Query: 338  IGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGP 397
              R  +    ++   G + +  +D   G +    + G  DR E     +  +      GP
Sbjct: 760  GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG--DRGE-----VGQIGPRGEDGP 812

Query: 398  PGPPG--GPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKAI 450
             GP G  GP   PG  G+   +G  G PG     G       T   G     G +  + +
Sbjct: 813  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 872

Query: 451  NQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPG 510
              + G       Q  P G         RGS        +   +   G   P GP PG  G
Sbjct: 873  AGKPGP----RGQRGPTGP--------RGSRGARGPTGKPGPKGTSGGDGPPGP-PGERG 919

Query: 511  PAGPMGPFN-PGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQ--PPAPHDPSKAAA 567
            P GP GP   PGP  +GPPG PP   G P H   P   G T  Q +  PP P        
Sbjct: 920  PQGPQGPVGFPGP--KGPPG-PPGKDGLPGH---PGQRGETGFQGKTGPPGPG----GVV 969

Query: 568  AAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSD---------- 617
                P           +  PPGP PG    P A   +G    P P G S           
Sbjct: 970  GPQGPTGETGPIGERGHPGPPGP-PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 1028

Query: 618  -----YTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG--------GP 664
                    A      K G+ PQ P  P              ++    T G        GP
Sbjct: 1029 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSP---------GERGSAGTAGPIGLPGRPGP 1079

Query: 665  GAPPGSQPDYSAAWAEYYRQQAAYYGQT-----PGPGGPQPPPTQQGQQ 708
              PPG   +  A   +  +  A   G       PGP GP   P + G +
Sbjct: 1080 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1128



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 182/691 (26%), Positives = 226/691 (32%), Gaps = 113/691 (16%)

Query: 5    STGGPPPGPP---PPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGGPGG--GGPGG 52
            S G  PPGPP    P G  G  G  G   PPGPPG        G RG  G  G  G PG 
Sbjct: 906  SGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP 965

Query: 53   GSAGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQ 111
            G   GP  P G  GP G R           + +    G + A          G  G+   
Sbjct: 966  GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA---KGDPGPQGISGKDGP 1022

Query: 112  LEDGDQPESKKL--ASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLI--IGRGGEQ- 166
                  P  + L  A     +    GP  PP       E R   G  G I   GR G Q 
Sbjct: 1023 AGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE-RGSAGTAGPIGLPGRPGPQG 1081

Query: 167  INKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDN 226
                  + G   +  P      +      G P     A    +D   +G  G PGQ    
Sbjct: 1082 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED-GDKGEIGEPGQKGSK 1140

Query: 227  ANGGQNGT--VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPL 283
             + G+NG      +  P G  G+  G G    +  Q   G K     +G++       P+
Sbjct: 1141 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG---DEGARGFPGPPGPI 1197

Query: 284  RIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSVGVV--IGR 340
             + G P    +  E   D+      G  G R   G     G D P  P  SVG V  +G 
Sbjct: 1198 GLQGLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGP---NGADGPQGPPGSVGSVGGVGE 1253

Query: 341  SGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPP-DRCEHAARIINDLLQSLRSGPPG 399
             GE       +AG           GP   A + GP  +R E              +GPPG
Sbjct: 1254 KGE-----PGEAG---------NPGPPGEAGVGGPKGERGEKG-----------EAGPPG 1288

Query: 400  PPGGPGM--PPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQTG 455
              G PG   PPG  G     G  G PG  G      P  + G+   +G +         G
Sbjct: 1289 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348

Query: 456  AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPM 515
                 S +  P G P       RG P       +  E+  +G     GP PG  GP GP 
Sbjct: 1349 P----SGEAGPPGPPG-----KRGPPGAAGAEGRQGEKGAKGEAGAEGP-PGKTGPVGPQ 1398

Query: 516  GPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNA 574
            GP   PGP  +G  G P    GP   Q  P   G    Q  PP P  P        DP +
Sbjct: 1399 GPAGKPGP--EGLRGIP----GPVGEQGLPGAAG----QDGPPGPMGPPGLPGLKGDPGS 1448

Query: 575  AWAAYYSHYYQ--QPPGP-----------------------VPGPAPAPAAPPAQGEP-P 608
                 +        PPG                        +PGPA     P   G P P
Sbjct: 1449 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP 1508

Query: 609  QPPPTGQSDYTKAWEEYYKKIGQQPQQPGAP 639
            Q P   +     A ++    +   P  PG P
Sbjct: 1509 QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1539



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 96/337 (28%), Positives = 116/337 (34%), Gaps = 67/337 (19%)

Query: 396  GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447
            GP GP G PG          PG +G    +G  GPPG       P    G+    GG+  
Sbjct: 1114 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP-GLQGPVGAPGIA---GGDGE 1169

Query: 448  KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE-GPLCPVGPGP 506
                 Q G F +        GD   + F     P  +        EK E G + P+GP P
Sbjct: 1170 PGPRGQQGMFGQ-------KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP-P 1221

Query: 507  GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPA--PHDPSK 564
            G PGP GP GP N     QGPPG+    GG      P +  GN  P  +     P     
Sbjct: 1222 GPPGPRGPQGP-NGADGPQGPPGSVGSVGGVGEKGEPGEA-GNPGPPGEAGVGGPKGERG 1279

Query: 565  AAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAPPAQGEPPQPPPTGQSDYT 619
                A  P AA         + PPG       PGP   P  P   G P +P P GQ    
Sbjct: 1280 EKGEAGPPGAAGPPGA----KGPPGDDGPKGNPGPVGFPGDP---GPPGEPGPAGQDGVG 1332

Query: 620  KAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWA 679
                E        P QPG P                       GP  PPG +    AA A
Sbjct: 1333 GDKGE-----DGDPGQPGPPGPSGEA-----------------GPPGPPGKRGPPGAAGA 1370

Query: 680  EYYRQQAAYYGQT--------PGPGGPQPPPTQQGQQ 708
            E  + +    G+          GP GPQ P  + G +
Sbjct: 1371 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE 1407



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 90/355 (25%), Positives = 122/355 (34%), Gaps = 70/355 (19%)

Query: 396  GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447
            GP G PG  G+P        PG  G+   +G  GPPG +     P  + G+   +G + V
Sbjct: 715  GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPR-GV---KGADGV 770

Query: 448  KAINQQTGAFVEISRQLPPNGDPNFKLFI-IRGSPQQIDHAKQLIEEKIEGPLCPVGPGP 506
            + +    G   E       +G P FK  + ++G   ++       E+  EGP    GP  
Sbjct: 771  RGLKGSKGEKGE-------DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP-T 822

Query: 507  GGPGPAGPMG-------PFNPG-PFNQGPPGAPPHAGGP----------------PPHQY 542
            G PGP+G  G       P  PG P  QGP G+    G P                P  Q 
Sbjct: 823  GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 882

Query: 543  PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV--PGPAPAPAA 600
             P G   +     P     P   +     P            Q P GPV  PGP   P  
Sbjct: 883  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG----ERGPQGPQGPVGFPGPKGPPGP 938

Query: 601  PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT 660
            P   G P  P   G++ +               Q    PP        +    +   +  
Sbjct: 939  PGKDGLPGHPGQRGETGF---------------QGKTGPPGPGGVVGPQGPTGETGPIGE 983

Query: 661  GG--GPGAPPGSQPDYSAAWAEYYRQQAAYYGQT--PGPGGPQPPPTQQGQQQAQ 711
             G  GP  PPG Q    AA  E  +      G +   GP G +  P ++G   AQ
Sbjct: 984  RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 1038



 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 68/235 (28%), Positives = 85/235 (36%), Gaps = 62/235 (26%)

Query: 495 IEGPLCPVGPGP--GGPGPAGPMGPFNPG-PFNQGPPGAPPHAG-----GPP------PH 540
           +EGP  P GP    G PG  GP GP  PG P ++GPPG P   G     GPP      P 
Sbjct: 440 VEGPPGPAGPAGIMGPPGLQGPTGP--PGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPF 497

Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPA 595
           +Y   G            P   ++ A A A    A  A      + PPGP+     PGP 
Sbjct: 498 RYGGDG---------SKGPTISAQEAQAQAILQQARIAL-----RGPPGPMGLTGRPGPV 543

Query: 596 PAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQ 655
             P +  A+GE   P P G                Q P  P   P             K+
Sbjct: 544 GGPGSSGAKGESGDPGPQGPRGV------------QGPPGPTGKP------------GKR 579

Query: 656 AQVATGGGPGAP--PGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708
            +    GG G P  PG++ D              + G+  GP GP  PP   G +
Sbjct: 580 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER-GPQGPPGPPGDDGMR 633



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 87/325 (26%), Positives = 110/325 (33%), Gaps = 55/325 (16%)

Query: 393 LRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGG-ENVKA 449
           L  GPPGP G  G+  PPG       QG  GPPG       P        GR G      
Sbjct: 439 LVEGPPGPAGPAGIMGPPGL------QGPTGPPGDPGDRGPP--------GRPGLPGADG 484

Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG----PG 505
           +    G  + +  +   +G    K   I     Q     Q     + GP  P+G    PG
Sbjct: 485 LPGPPGTMLMLPFRYGGDGS---KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG 541

Query: 506 P-GGPGPAGPMGPF-NPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPS 563
           P GGPG +G  G   +PGP  QGP G      GPP     P   G          P +P 
Sbjct: 542 PVGGPGSSGAKGESGDPGP--QGPRGVQ----GPPGPTGKPGKRGRPGADGGRGMPGEPG 595

Query: 564 KAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWE 623
                  D          H  ++ P   PGP   P     +GE  +  P G        E
Sbjct: 596 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGP---PGDDGMRGEDGEIGPRGLPG-----E 647

Query: 624 EYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYR 683
              + +      PGAP Q       +     +  +   G PG PPG Q +          
Sbjct: 648 AGPRGLLGPRGTPGAPGQPGMAGV-DGPPGPKGNMGPQGEPG-PPGQQGNPGPQ------ 699

Query: 684 QQAAYYGQTPGPGGPQPPPTQQGQQ 708
                    PGP GP  PP ++G Q
Sbjct: 700 -------GLPGPQGPIGPPGEKGPQ 717



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 27/61 (44%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGGGGP 67
            G P   G GG  G AG   PPGPPG     G  G  G  GP G  G +G P  P   G P
Sbjct: 1480 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1539

Query: 68   G 68
            G
Sbjct: 1540 G 1540



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 11/78 (14%)

Query: 3    DYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGA-------GDRGGGGPGG--GGPGGG 53
            D    G P  P PP G  G AG  G     GPPGA       G++G  G  G  G PG  
Sbjct: 1334 DKGEDGDPGQPGPP-GPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1392

Query: 54   SAGGPSQPPGGGGP-GIR 70
               GP  P G  GP G+R
Sbjct: 1393 GPVGPQGPAGKPGPEGLR 1410



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 53/169 (31%), Positives = 65/169 (38%), Gaps = 37/169 (21%)

Query: 8   GPPPGPPPPA--GGGGGAGGAGGGPPPGPPG-AGDRG----GGGPGGGGPGG-----GSA 55
           GP   P PP   G  G  G  G   P GPPG  G +G     G PG  GP G     G +
Sbjct: 682 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 741

Query: 56  G-----GPSQPPGG-GGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQK 109
           G     GP  P G  G PG R    AD V+  +    + G D            GF G K
Sbjct: 742 GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED------------GFPGFK 789

Query: 110 RQLE-DGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVG 157
             +   GD+ E  ++  +G+      GP  P  R   T +   P G  G
Sbjct: 790 GDMGLKGDRGEVGQIGPRGED-----GPEGPKGRAGPTGD-PGPSGQAG 832



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 20/44 (45%), Positives = 20/44 (45%), Gaps = 3/44 (6%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRG-GGGPGGGGPGG 52
            PPGPP   G  G  G  G   P G    GD G  G PG  GP G
Sbjct: 1499 PPGPPGLPGPQGPKGNKGSTGPAGQ--KGDSGLPGPPGSPGPPG 1540


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 151/563 (26%), Positives = 189/563 (33%), Gaps = 83/563 (14%)

Query: 5    STGGP-------PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGS 54
            + GGP       P GPP PAG  G  G AG G P GPPG  G +G  G  G  G PG   
Sbjct: 909  TAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKG 968

Query: 55   AGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLE 113
              GP+   G  GP G+   A    V        ++G         +  + G  G    + 
Sbjct: 969  PIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1028

Query: 114  DGDQPESKKLASQGDSISSQLGPI--HPPPRTSMTEEYRVPDGMVGL--IIGRGGEQINK 169
               QP     A+  D      GP           T  +  P G +GL  + G  GE+   
Sbjct: 1029 PVGQPG----AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK--- 1081

Query: 170  IQQDSGCKVQISPDSGGLPERSVSLTGA--PESVQKAKMMLDDIVSRGRGGPPGQFHDNA 227
               ++G    + P     P       GA  P+               G  GPPG+  +  
Sbjct: 1082 --GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV---------GNLGPPGEKGEPG 1130

Query: 228  NGGQNGTVQE--IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285
              G  G   E  +  P G+ G    KG           G K     DG +      P+  
Sbjct: 1131 ESGSPGIQGEPGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGF 1185

Query: 286  IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMI 345
             GDP    +      D       G  GDR E G     G   P   +     +G+ G   
Sbjct: 1186 PGDPGPPGEGGPRGQD-------GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGP-- 1236

Query: 346  KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPG 405
                  AG      +  G G +     +G P +             +  +G PGP G  G
Sbjct: 1237 ------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG-------PAGPAGKPGPDGLRG 1283

Query: 406  MPP--GGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQ 463
            +P   G +GR    G  GPPG       P    GL   RG    K      G    I   
Sbjct: 1284 LPGSVGQQGRPGATGQAGPPG-------PVGPPGLPGLRGDAGAKGEKGHPGLIGLIG-- 1334

Query: 464  LPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG--PGGPGPAGPMGPFNPG 521
              P G+   K    RG P       Q  E  I G   P+GPG  PG PGPAGP G    G
Sbjct: 1335 --PPGEQGEKGD--RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA--KG 1388

Query: 522  PFNQGPPGAPPHAGGPPPHQYPP 544
                G P       GPP H  PP
Sbjct: 1389 ATGPGGPKGEKGVQGPPGHPGPP 1411



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 170/639 (26%), Positives = 213/639 (33%), Gaps = 136/639 (21%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPPGGGG--- 66
            GP    G  G  G +GG  P GPPG  +RG  GP G  G PG     GP  PPG  G   
Sbjct: 764  GPRGATGKSGAKGTSGGDGPHGPPG--ERGLPGPQGPNGFPG---PKGPPGPPGKDGLPG 818

Query: 67   -PGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQL-EDGDQPESKKLA 124
             PG R +               +G   A        + G  G      E G    + K  
Sbjct: 819  HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEG 878

Query: 125  SQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDS 184
            ++GD      GP   P +         P G  GL    GG  +   +  SG      P  
Sbjct: 879  TKGDP-----GPPGAPGKDGPAGLRGFP-GERGLPGTAGGPGLKGNEGPSG-----PPGP 927

Query: 185  GGLP-ERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAG 243
             G P ER  + +G P         +      G  GPPG   +    G+ G +     P G
Sbjct: 928  AGSPGERGAAGSGGP---------IGPPGRPGPQGPPGAAGEKGVPGEKGPIG----PTG 974

Query: 244  KAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDIL 303
            + G V G  G     L   AG   +  +DG +          +GDP              
Sbjct: 975  RDG-VQGPVG-----LPGPAGPPGVAGEDGDKGE--------VGDP-------------- 1006

Query: 304  RERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDG 363
                +G  G++ E+G     G   PV +       G  G   +  Q   G     K D+G
Sbjct: 1007 --GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG--ARGPQGHFGA----KGDEG 1058

Query: 364  T-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRG 416
            T       GP  +  + GP         +          GP GPPG PG P G  G    
Sbjct: 1059 TRGFNGPPGPIGLQGLPGPSGEKGETGDV----------GPMGPPGPPG-PRGPAGPNGA 1107

Query: 417  QGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFI 476
             G  GPPGG      P  K     G  GE+     Q               G+P  K   
Sbjct: 1108 DGPQGPPGGVGNLGPPGEK-----GEPGESGSPGIQ---------------GEPGVK--G 1145

Query: 477  IRGSPQQIDHAKQLIEEKIEGPLCPVG-PGP-GGPGPAGPMGPFNPGPFNQGPP------ 528
             RG   +   + Q  E    GP  P G  GP G PGP G   P +PGP  +G P      
Sbjct: 1146 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG--FPGDPGPPGEGGPRGQDGA 1203

Query: 529  -------GAPPHAGGPPP--HQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAY 579
                   G P   G P P     PP   G   P    P          A  DP A  A  
Sbjct: 1204 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS-PGSEGRQGGKGAKGDPGAIGAPG 1262

Query: 580  YSHYYQQPPGPV--PGPAPAPAAPPAQGEPPQPPPTGQS 616
             +     P GP   PGP      P + G+  +P  TGQ+
Sbjct: 1263 KTGPV-GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1300



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 199/748 (26%), Positives = 250/748 (33%), Gaps = 158/748 (21%)

Query: 10  PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG------ 63
           PPGP  PAG  G  G  G    PGP   GD G  GP G     GS G P  PPG      
Sbjct: 314 PPGPEGPAGLIGPPGIQGN---PGP--VGDPGERGPPGRAGLPGSDGAPG-PPGTSLMLP 367

Query: 64  ---GGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120
              G G G +    A    +A+ I  +    A   +       G+ G+   L    QP S
Sbjct: 368 FRFGSGGGDKGPVVAAQEAQAQAILQQ----ARLALRGPPGPMGYTGRPGPL---GQPGS 420

Query: 121 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI 180
             L  +    S  LGP  P     +T     P G  G     G +    +  D G K   
Sbjct: 421 PGLKGE----SGDLGPQGPRGPQGLTG----PPGKAGRRGRAGADGARGMPGDPGVKGDR 472

Query: 181 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI 240
             D  GLP       G P      K    D  ++G  GPPG+  +  + G+ G  + +  
Sbjct: 473 GFD--GLP-------GLPGE----KGHRGDTGAQGLPGPPGEDGERGDDGEIGP-RGLPG 518

Query: 241 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM 300
            +G  GL+  KG   I       G   +   DG Q      P   +G             
Sbjct: 519 ESGPRGLLGPKGPPGIP------GPPGVRGMDGPQG-----PKGSLGP------------ 555

Query: 301 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360
                  QG  G   + G+   G   +P P+ +    IG  GE  K  Q   G+      
Sbjct: 556 -------QGEPGPPGQQGTP--GTQGLPGPQGA----IGPHGE--KGPQGKPGLPGMPGS 600

Query: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420
           D   GP       GPP    +             SGP GP G PG P G +G    +G  
Sbjct: 601 D---GPPGHPGKEGPPGTKGNQGP----------SGPQGPLGYPG-PRGVKGVDGIRGLK 646

Query: 421 GPPGGEMTFSIPTHK--CGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIR 478
           G  G +     P  K   G+   RG   V     + G      R   P GDP        
Sbjct: 647 GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGR-TGPTGDP-------- 697

Query: 479 GSPQQIDHAKQLIEEKI------EGPLCPVG----PGPGG----------PGPAGPMGPF 518
           G P  +    +L    +      +GP   +G    PG  G           GP G  GP 
Sbjct: 698 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 757

Query: 519 NP----GPFN-QGPPGAPPHAGGPPPHQYP-------PQGWGNTYPQWQPPAPHDPSKAA 566
            P    GP    G  GA   +GG  PH  P       PQG  N +P   P  P  P    
Sbjct: 758 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG-PNGFP--GPKGPPGPPGKD 814

Query: 567 AAAADPNAAWAAYYSHYYQQPPGP--VPGPAPAPAAPPAQGEPPQP----PPTGQSDYTK 620
                P       +      PPGP  V GP  A       GE   P    PP  Q     
Sbjct: 815 GLPGHPGQRGEVGFQG-KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 873

Query: 621 AWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE 680
           A +E  K     P  PGA P +D       +  ++    T GGPG      P      A 
Sbjct: 874 AGKEGTK---GDPGPPGA-PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 929

Query: 681 YYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708
              ++ A      G GGP  PP + G Q
Sbjct: 930 SPGERGA-----AGSGGPIGPPGRPGPQ 952



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 207/824 (25%), Positives = 255/824 (30%), Gaps = 242/824 (29%)

Query: 8    GPP--PGPPPPAGGGGGAGGAGG-------GPP-----------PGPPGA-GDRGGGGPG 46
            GPP  PGPP   G  G  G  G        GPP           PGP GA G  G  GP 
Sbjct: 530  GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 589

Query: 47   G--GGPG-GGSAGGPSQPPGGGGPGIRKDAFADAVQ------RARQIAAKIGGDAATTVN 97
            G  G PG  GS G P  P   G PG + +      Q        R +    G        
Sbjct: 590  GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHK 649

Query: 98   NSTPDFGFGGQKRQL-EDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMV 156
                + GF G K  +   GD+ E     S+G+      GP  P  RT  T +     G  
Sbjct: 650  GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-----GPEGPKGRTGPTGD----PGPP 700

Query: 157  GLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAP-ESVQKAKMMLDDIVSRG 215
            GL+  +G   +  +    G +          P+ S+   G P  S +K    L      G
Sbjct: 701  GLMGEKGKLGVPGLPGYPGRQG---------PKGSLGFPGFPGASGEKGARGLS-----G 746

Query: 216  RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
            + GP G+       GQ G         GK+G     GG+         G+       G Q
Sbjct: 747  KSGPRGERGPTGPRGQRGP----RGATGKSGAKGTSGGDGPHGPPGERGL------PGPQ 796

Query: 276  NTN-VDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSV 334
              N    P    G P K             +   G  G R E G +  G    P P   V
Sbjct: 797  GPNGFPGPKGPPGPPGK-------------DGLPGHPGQRGEVGFQ--GKTGPPGPPGVV 841

Query: 335  GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394
            G   G +GE                    TGP       GPP              +  +
Sbjct: 842  GPQ-GAAGE--------------------TGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 880

Query: 395  SGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQ 452
              P GPPG PG   P G RG    +G  G  GG           GL   +G E       
Sbjct: 881  GDP-GPPGAPGKDGPAGLRGFPGERGLPGTAGGP----------GL---KGNEG------ 920

Query: 453  QTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512
                         P+G P        GSP          E    G   P+GP PG PGP 
Sbjct: 921  -------------PSGPPG-----PAGSPG---------ERGAAGSGGPIGP-PGRPGPQ 952

Query: 513  GPMG-------PFNPGPFN-------QGPPGAPPHAGGP-------------PPHQYPPQ 545
            GP G       P   GP         QGP G P  AG P              P Q   +
Sbjct: 953  GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 1012

Query: 546  GWGNTYPQWQPPAPHDP-SKAAAAAADPNAAWAAYYSHY----------YQQPPGPV--- 591
            G    +    PP P  P  +  AA AD          H+          +  PPGP+   
Sbjct: 1013 GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1072

Query: 592  --PGPA--------------PAPAAP-----PAQGEPPQPPPTGQSDYTKAWEE------ 624
              PGP+              P P  P     P   + PQ PP G  +     E+      
Sbjct: 1073 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1132

Query: 625  ------------------YYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGA 666
                                K    QP +PG PP        +        V   G PG 
Sbjct: 1133 GSPGIQGEPGVKGPRGERGEKGESGQPGEPG-PPGPKGPTGDDGPKGNPGPVGFPGDPG- 1190

Query: 667  PPGSQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQGQQ 708
            PPG         A+  R +    GQ  +PGP G   PP   G++
Sbjct: 1191 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 2/67 (2%)

Query: 3    DYSTGGPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60
            D    G P  PG P P G  G  G  G   P G PG+  R GG    G PG   A G + 
Sbjct: 1206 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265

Query: 61   PPGGGGP 67
            P G  GP
Sbjct: 1266 PVGPAGP 1272



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 80/305 (26%), Positives = 107/305 (35%), Gaps = 45/305 (14%)

Query: 10   PPGPPPPAGGGGGAGGAG--GGP-PPGPPG-AGDRGGGGPGG-----GGPGGGSAGGPSQ 60
            PPGP  P G  G  G  G  G P  PGPPG  G RG  G  G     G PG   + GP+ 
Sbjct: 1164 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1223

Query: 61   PPGGGGPGIRKDAFADAVQRARQIAAKIGGD--AATTVNNSTPDFGFGGQKRQLEDGDQP 118
              G  GP  ++          RQ      GD  A      + P    G   +   DG + 
Sbjct: 1224 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1283

Query: 119  ESKKLASQG----DSISSQLGPIHPPPRTSM-----TEEYRVPDGMVGLIIGRGGEQINK 169
                +  QG       +   GP+ PP    +      +  +   G++GL IG  GEQ  K
Sbjct: 1284 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL-IGPPGEQGEK 1342

Query: 170  IQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANG 229
                 G +    P      +  + + GA   +             G GGPPG        
Sbjct: 1343 -----GDRGLPGPQGSPGQKGEMGIPGASGPI-------------GPGGPPGLPGPAGPK 1384

Query: 230  GQNGTVQEIMIPAGKAGLV-----IGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLR 284
            G  G       P G+ G+       G  GE I+ L  +   K     DGS+    D+ + 
Sbjct: 1385 GAKGATGP-GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1443

Query: 285  IIGDP 289
              G P
Sbjct: 1444 TGGAP 1448



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/133 (30%), Positives = 50/133 (37%), Gaps = 22/133 (16%)

Query: 495 IEGPLCPVGP----GP----GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQG 546
           +EGP  P GP    GP    G PGP G  G   P P   G PG+    G P      P  
Sbjct: 311 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-PGRAGLPGSDGAPGPPGTSLMLPFR 369

Query: 547 WGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAP 601
           +G+      P      ++A A       A         + PPGP+     PGP   P +P
Sbjct: 370 FGSGGGDKGPVVAAQEAQAQAILQQARLA--------LRGPPGPMGYTGRPGPLGQPGSP 421

Query: 602 PAQGEPPQPPPTG 614
             +GE     P G
Sbjct: 422 GLKGESGDLGPQG 434



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 33/85 (38%), Positives = 35/85 (41%), Gaps = 20/85 (23%)

Query: 3    DYSTGGP--PPGPPPPAGGGGG------AGGAGGGPPPGPPGAGDRGG-----GGPGGGG 49
            D    GP  PPGP  PAG  G        GG G   PPG  G     G     G PG  G
Sbjct: 1086 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1145

Query: 50   PGG-----GSAGGPSQ--PPGGGGP 67
            P G     G +G P +  PPG  GP
Sbjct: 1146 PRGERGEKGESGQPGEPGPPGPKGP 1170



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 47/164 (28%), Positives = 59/164 (35%), Gaps = 45/164 (27%)

Query: 393 LRSGPPGPPGGPGM--------------------PPGGRGRGRGQGNWGPPGGEMTFSIP 432
           L  GPPGP G  G+                    PPG  G     G  GPPG  +     
Sbjct: 310 LVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPF- 368

Query: 433 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIE 492
             + G   G  G  V A   Q  A ++ +R              +RG P  + +  +   
Sbjct: 369 --RFGSGGGDKGPVVAAQEAQAQAILQQAR------------LALRGPPGPMGYTGR--- 411

Query: 493 EKIEGPLCPVGPGPGGPGPAGPMGPFNP-GPFNQGPPGAPPHAG 535
               GPL   G  PG  G +G +GP  P GP  QG  G P  AG
Sbjct: 412 ---PGPLGQPG-SPGLKGESGDLGPQGPRGP--QGLTGPPGKAG 449



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

Query: 5    STGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPP 62
            ++G   PG PP   G  G  GA G   PG P  G++G  GP G  G PG      P Q P
Sbjct: 1365 ASGPIGPGGPPGLPGPAGPKGAKGATGPGGP-KGEKGVQGPPGHPGPPGEVIQPLPIQMP 1423



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 5/34 (14%)

Query: 396  GPPGPPG-----GPGMPPGGRGRGRGQGNWGPPG 424
            GP GP G     GPG P G +G     G+ GPPG
Sbjct: 1379 GPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 151/563 (26%), Positives = 189/563 (33%), Gaps = 83/563 (14%)

Query: 5    STGGP-------PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGS 54
            + GGP       P GPP PAG  G  G AG G P GPPG  G +G  G  G  G PG   
Sbjct: 888  TAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKG 947

Query: 55   AGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLE 113
              GP+   G  GP G+   A    V        ++G         +  + G  G    + 
Sbjct: 948  PIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1007

Query: 114  DGDQPESKKLASQGDSISSQLGPI--HPPPRTSMTEEYRVPDGMVGL--IIGRGGEQINK 169
               QP     A+  D      GP           T  +  P G +GL  + G  GE+   
Sbjct: 1008 PVGQPG----AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK--- 1060

Query: 170  IQQDSGCKVQISPDSGGLPERSVSLTGA--PESVQKAKMMLDDIVSRGRGGPPGQFHDNA 227
               ++G    + P     P       GA  P+               G  GPPG+  +  
Sbjct: 1061 --GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV---------GNLGPPGEKGEPG 1109

Query: 228  NGGQNGTVQE--IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285
              G  G   E  +  P G+ G    KG           G K     DG +      P+  
Sbjct: 1110 ESGSPGIQGEPGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGF 1164

Query: 286  IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMI 345
             GDP    +      D       G  GDR E G     G   P   +     +G+ G   
Sbjct: 1165 PGDPGPPGEGGPRGQD-------GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGP-- 1215

Query: 346  KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPG 405
                  AG      +  G G +     +G P +             +  +G PGP G  G
Sbjct: 1216 ------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG-------PAGPAGKPGPDGLRG 1262

Query: 406  MPP--GGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQ 463
            +P   G +GR    G  GPPG       P    GL   RG    K      G    I   
Sbjct: 1263 LPGSVGQQGRPGATGQAGPPG-------PVGPPGLPGLRGDAGAKGEKGHPGLIGLIG-- 1313

Query: 464  LPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG--PGGPGPAGPMGPFNPG 521
              P G+   K    RG P       Q  E  I G   P+GPG  PG PGPAGP G    G
Sbjct: 1314 --PPGEQGEKGD--RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA--KG 1367

Query: 522  PFNQGPPGAPPHAGGPPPHQYPP 544
                G P       GPP H  PP
Sbjct: 1368 ATGPGGPKGEKGVQGPPGHPGPP 1390



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 170/639 (26%), Positives = 213/639 (33%), Gaps = 136/639 (21%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPPGGGG--- 66
            GP    G  G  G +GG  P GPPG  +RG  GP G  G PG     GP  PPG  G   
Sbjct: 743  GPRGATGKSGAKGTSGGDGPHGPPG--ERGLPGPQGPNGFPG---PKGPPGPPGKDGLPG 797

Query: 67   -PGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQL-EDGDQPESKKLA 124
             PG R +               +G   A        + G  G      E G    + K  
Sbjct: 798  HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEG 857

Query: 125  SQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDS 184
            ++GD      GP   P +         P G  GL    GG  +   +  SG      P  
Sbjct: 858  TKGDP-----GPPGAPGKDGPAGLRGFP-GERGLPGTAGGPGLKGNEGPSG-----PPGP 906

Query: 185  GGLP-ERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAG 243
             G P ER  + +G P         +      G  GPPG   +    G+ G +     P G
Sbjct: 907  AGSPGERGAAGSGGP---------IGPPGRPGPQGPPGAAGEKGVPGEKGPIG----PTG 953

Query: 244  KAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDIL 303
            + G V G  G     L   AG   +  +DG +          +GDP              
Sbjct: 954  RDG-VQGPVG-----LPGPAGPPGVAGEDGDKGE--------VGDP-------------- 985

Query: 304  RERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDG 363
                +G  G++ E+G     G   PV +       G  G   +  Q   G     K D+G
Sbjct: 986  --GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG--ARGPQGHFGA----KGDEG 1037

Query: 364  T-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRG 416
            T       GP  +  + GP         +          GP GPPG PG P G  G    
Sbjct: 1038 TRGFNGPPGPIGLQGLPGPSGEKGETGDV----------GPMGPPGPPG-PRGPAGPNGA 1086

Query: 417  QGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFI 476
             G  GPPGG      P  K     G  GE+     Q               G+P  K   
Sbjct: 1087 DGPQGPPGGVGNLGPPGEK-----GEPGESGSPGIQ---------------GEPGVK--G 1124

Query: 477  IRGSPQQIDHAKQLIEEKIEGPLCPVG-PGP-GGPGPAGPMGPFNPGPFNQGPP------ 528
             RG   +   + Q  E    GP  P G  GP G PGP G   P +PGP  +G P      
Sbjct: 1125 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG--FPGDPGPPGEGGPRGQDGA 1182

Query: 529  -------GAPPHAGGPPP--HQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAY 579
                   G P   G P P     PP   G   P    P          A  DP A  A  
Sbjct: 1183 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS-PGSEGRQGGKGAKGDPGAIGAPG 1241

Query: 580  YSHYYQQPPGPV--PGPAPAPAAPPAQGEPPQPPPTGQS 616
             +     P GP   PGP      P + G+  +P  TGQ+
Sbjct: 1242 KTGPV-GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1279



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 199/748 (26%), Positives = 250/748 (33%), Gaps = 158/748 (21%)

Query: 10  PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG------ 63
           PPGP  PAG  G  G  G    PGP   GD G  GP G     GS G P  PPG      
Sbjct: 293 PPGPEGPAGLIGPPGIQGN---PGP--VGDPGERGPPGRAGLPGSDGAPG-PPGTSLMLP 346

Query: 64  ---GGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120
              G G G +    A    +A+ I  +    A   +       G+ G+   L    QP S
Sbjct: 347 FRFGSGGGDKGPVVAAQEAQAQAILQQ----ARLALRGPPGPMGYTGRPGPL---GQPGS 399

Query: 121 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI 180
             L  +    S  LGP  P     +T     P G  G     G +    +  D G K   
Sbjct: 400 PGLKGE----SGDLGPQGPRGPQGLTG----PPGKAGRRGRAGADGARGMPGDPGVKGDR 451

Query: 181 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI 240
             D  GLP       G P      K    D  ++G  GPPG+  +  + G+ G  + +  
Sbjct: 452 GFD--GLP-------GLPGE----KGHRGDTGAQGLPGPPGEDGERGDDGEIGP-RGLPG 497

Query: 241 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM 300
            +G  GL+  KG   I       G   +   DG Q      P   +G             
Sbjct: 498 ESGPRGLLGPKGPPGIP------GPPGVRGMDGPQG-----PKGSLGP------------ 534

Query: 301 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360
                  QG  G   + G+   G   +P P+ +    IG  GE  K  Q   G+      
Sbjct: 535 -------QGEPGPPGQQGTP--GTQGLPGPQGA----IGPHGE--KGPQGKPGLPGMPGS 579

Query: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420
           D   GP       GPP    +             SGP GP G PG P G +G    +G  
Sbjct: 580 D---GPPGHPGKEGPPGTKGNQGP----------SGPQGPLGYPG-PRGVKGVDGIRGLK 625

Query: 421 GPPGGEMTFSIPTHK--CGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIR 478
           G  G +     P  K   G+   RG   V     + G      R   P GDP        
Sbjct: 626 GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGR-TGPTGDP-------- 676

Query: 479 GSPQQIDHAKQLIEEKI------EGPLCPVG----PGPGG----------PGPAGPMGPF 518
           G P  +    +L    +      +GP   +G    PG  G           GP G  GP 
Sbjct: 677 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 736

Query: 519 NP----GPFN-QGPPGAPPHAGGPPPHQYP-------PQGWGNTYPQWQPPAPHDPSKAA 566
            P    GP    G  GA   +GG  PH  P       PQG  N +P   P  P  P    
Sbjct: 737 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG-PNGFP--GPKGPPGPPGKD 793

Query: 567 AAAADPNAAWAAYYSHYYQQPPGP--VPGPAPAPAAPPAQGEPPQP----PPTGQSDYTK 620
                P       +      PPGP  V GP  A       GE   P    PP  Q     
Sbjct: 794 GLPGHPGQRGEVGFQG-KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 852

Query: 621 AWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE 680
           A +E  K     P  PGA P +D       +  ++    T GGPG      P      A 
Sbjct: 853 AGKEGTK---GDPGPPGA-PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 908

Query: 681 YYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708
              ++ A      G GGP  PP + G Q
Sbjct: 909 SPGERGA-----AGSGGPIGPPGRPGPQ 931



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 207/824 (25%), Positives = 255/824 (30%), Gaps = 242/824 (29%)

Query: 8    GPP--PGPPPPAGGGGGAGGAGG-------GPP-----------PGPPGA-GDRGGGGPG 46
            GPP  PGPP   G  G  G  G        GPP           PGP GA G  G  GP 
Sbjct: 509  GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 568

Query: 47   G--GGPG-GGSAGGPSQPPGGGGPGIRKDAFADAVQ------RARQIAAKIGGDAATTVN 97
            G  G PG  GS G P  P   G PG + +      Q        R +    G        
Sbjct: 569  GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHK 628

Query: 98   NSTPDFGFGGQKRQL-EDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMV 156
                + GF G K  +   GD+ E     S+G+      GP  P  RT  T +     G  
Sbjct: 629  GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-----GPEGPKGRTGPTGD----PGPP 679

Query: 157  GLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAP-ESVQKAKMMLDDIVSRG 215
            GL+  +G   +  +    G +          P+ S+   G P  S +K    L      G
Sbjct: 680  GLMGEKGKLGVPGLPGYPGRQG---------PKGSLGFPGFPGASGEKGARGLS-----G 725

Query: 216  RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
            + GP G+       GQ G         GK+G     GG+         G+       G Q
Sbjct: 726  KSGPRGERGPTGPRGQRGP----RGATGKSGAKGTSGGDGPHGPPGERGL------PGPQ 775

Query: 276  NTN-VDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSV 334
              N    P    G P K             +   G  G R E G +  G    P P   V
Sbjct: 776  GPNGFPGPKGPPGPPGK-------------DGLPGHPGQRGEVGFQ--GKTGPPGPPGVV 820

Query: 335  GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394
            G   G +GE                    TGP       GPP              +  +
Sbjct: 821  GPQ-GAAGE--------------------TGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 859

Query: 395  SGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQ 452
              P GPPG PG   P G RG    +G  G  GG           GL   +G E       
Sbjct: 860  GDP-GPPGAPGKDGPAGLRGFPGERGLPGTAGGP----------GL---KGNEG------ 899

Query: 453  QTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512
                         P+G P        GSP          E    G   P+GP PG PGP 
Sbjct: 900  -------------PSGPPG-----PAGSPG---------ERGAAGSGGPIGP-PGRPGPQ 931

Query: 513  GPMG-------PFNPGPFN-------QGPPGAPPHAGGP-------------PPHQYPPQ 545
            GP G       P   GP         QGP G P  AG P              P Q   +
Sbjct: 932  GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 991

Query: 546  GWGNTYPQWQPPAPHDP-SKAAAAAADPNAAWAAYYSHY----------YQQPPGPV--- 591
            G    +    PP P  P  +  AA AD          H+          +  PPGP+   
Sbjct: 992  GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1051

Query: 592  --PGPA--------------PAPAAP-----PAQGEPPQPPPTGQSDYTKAWEE------ 624
              PGP+              P P  P     P   + PQ PP G  +     E+      
Sbjct: 1052 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1111

Query: 625  ------------------YYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGA 666
                                K    QP +PG PP        +        V   G PG 
Sbjct: 1112 GSPGIQGEPGVKGPRGERGEKGESGQPGEPG-PPGPKGPTGDDGPKGNPGPVGFPGDPG- 1169

Query: 667  PPGSQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQGQQ 708
            PPG         A+  R +    GQ  +PGP G   PP   G++
Sbjct: 1170 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 2/67 (2%)

Query: 3    DYSTGGPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60
            D    G P  PG P P G  G  G  G   P G PG+  R GG    G PG   A G + 
Sbjct: 1185 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1244

Query: 61   PPGGGGP 67
            P G  GP
Sbjct: 1245 PVGPAGP 1251



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 80/305 (26%), Positives = 107/305 (35%), Gaps = 45/305 (14%)

Query: 10   PPGPPPPAGGGGGAGGAG--GGP-PPGPPG-AGDRGGGGPGG-----GGPGGGSAGGPSQ 60
            PPGP  P G  G  G  G  G P  PGPPG  G RG  G  G     G PG   + GP+ 
Sbjct: 1143 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1202

Query: 61   PPGGGGPGIRKDAFADAVQRARQIAAKIGGD--AATTVNNSTPDFGFGGQKRQLEDGDQP 118
              G  GP  ++          RQ      GD  A      + P    G   +   DG + 
Sbjct: 1203 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1262

Query: 119  ESKKLASQG----DSISSQLGPIHPPPRTSM-----TEEYRVPDGMVGLIIGRGGEQINK 169
                +  QG       +   GP+ PP    +      +  +   G++GL IG  GEQ  K
Sbjct: 1263 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL-IGPPGEQGEK 1321

Query: 170  IQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANG 229
                 G +    P      +  + + GA   +             G GGPPG        
Sbjct: 1322 -----GDRGLPGPQGSPGQKGEMGIPGASGPI-------------GPGGPPGLPGPAGPK 1363

Query: 230  GQNGTVQEIMIPAGKAGLV-----IGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLR 284
            G  G       P G+ G+       G  GE I+ L  +   K     DGS+    D+ + 
Sbjct: 1364 GAKGATGP-GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1422

Query: 285  IIGDP 289
              G P
Sbjct: 1423 TGGAP 1427



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/133 (30%), Positives = 50/133 (37%), Gaps = 22/133 (16%)

Query: 495 IEGPLCPVGP----GP----GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQG 546
           +EGP  P GP    GP    G PGP G  G   P P   G PG+    G P      P  
Sbjct: 290 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-PGRAGLPGSDGAPGPPGTSLMLPFR 348

Query: 547 WGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAP 601
           +G+      P      ++A A       A         + PPGP+     PGP   P +P
Sbjct: 349 FGSGGGDKGPVVAAQEAQAQAILQQARLA--------LRGPPGPMGYTGRPGPLGQPGSP 400

Query: 602 PAQGEPPQPPPTG 614
             +GE     P G
Sbjct: 401 GLKGESGDLGPQG 413



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 33/85 (38%), Positives = 35/85 (41%), Gaps = 20/85 (23%)

Query: 3    DYSTGGP--PPGPPPPAGGGGG------AGGAGGGPPPGPPGAGDRGG-----GGPGGGG 49
            D    GP  PPGP  PAG  G        GG G   PPG  G     G     G PG  G
Sbjct: 1065 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1124

Query: 50   PGG-----GSAGGPSQ--PPGGGGP 67
            P G     G +G P +  PPG  GP
Sbjct: 1125 PRGERGEKGESGQPGEPGPPGPKGP 1149



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 47/164 (28%), Positives = 59/164 (35%), Gaps = 45/164 (27%)

Query: 393 LRSGPPGPPGGPGM--------------------PPGGRGRGRGQGNWGPPGGEMTFSIP 432
           L  GPPGP G  G+                    PPG  G     G  GPPG  +     
Sbjct: 289 LVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPF- 347

Query: 433 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIE 492
             + G   G  G  V A   Q  A ++ +R              +RG P  + +  +   
Sbjct: 348 --RFGSGGGDKGPVVAAQEAQAQAILQQAR------------LALRGPPGPMGYTGR--- 390

Query: 493 EKIEGPLCPVGPGPGGPGPAGPMGPFNP-GPFNQGPPGAPPHAG 535
               GPL   G  PG  G +G +GP  P GP  QG  G P  AG
Sbjct: 391 ---PGPLGQPG-SPGLKGESGDLGPQGPRGP--QGLTGPPGKAG 428



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

Query: 5    STGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPP 62
            ++G   PG PP   G  G  GA G   PG P  G++G  GP G  G PG      P Q P
Sbjct: 1344 ASGPIGPGGPPGLPGPAGPKGAKGATGPGGP-KGEKGVQGPPGHPGPPGEVIQPLPIQMP 1402



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 5/34 (14%)

Query: 396  GPPGPPG-----GPGMPPGGRGRGRGQGNWGPPG 424
            GP GP G     GPG P G +G     G+ GPPG
Sbjct: 1358 GPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 151/563 (26%), Positives = 189/563 (33%), Gaps = 83/563 (14%)

Query: 5    STGGP-------PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGS 54
            + GGP       P GPP PAG  G  G AG G P GPPG  G +G  G  G  G PG   
Sbjct: 995  TAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKG 1054

Query: 55   AGGPSQPPGGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLE 113
              GP+   G  GP G+   A    V        ++G         +  + G  G    + 
Sbjct: 1055 PIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1114

Query: 114  DGDQPESKKLASQGDSISSQLGPI--HPPPRTSMTEEYRVPDGMVGL--IIGRGGEQINK 169
               QP     A+  D      GP           T  +  P G +GL  + G  GE+   
Sbjct: 1115 PVGQPG----AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEK--- 1167

Query: 170  IQQDSGCKVQISPDSGGLPERSVSLTGA--PESVQKAKMMLDDIVSRGRGGPPGQFHDNA 227
               ++G    + P     P       GA  P+               G  GPPG+  +  
Sbjct: 1168 --GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV---------GNLGPPGEKGEPG 1216

Query: 228  NGGQNGTVQE--IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285
              G  G   E  +  P G+ G    KG           G K     DG +      P+  
Sbjct: 1217 ESGSPGIQGEPGVKGPRGERG---EKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGF 1271

Query: 286  IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMI 345
             GDP    +      D       G  GDR E G     G   P   +     +G+ G   
Sbjct: 1272 PGDPGPPGEGGPRGQD-------GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGP-- 1322

Query: 346  KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPG 405
                  AG      +  G G +     +G P +             +  +G PGP G  G
Sbjct: 1323 ------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG-------PAGPAGKPGPDGLRG 1369

Query: 406  MPP--GGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQ 463
            +P   G +GR    G  GPPG       P    GL   RG    K      G    I   
Sbjct: 1370 LPGSVGQQGRPGATGQAGPPG-------PVGPPGLPGLRGDAGAKGEKGHPGLIGLIG-- 1420

Query: 464  LPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG--PGGPGPAGPMGPFNPG 521
              P G+   K    RG P       Q  E  I G   P+GPG  PG PGPAGP G    G
Sbjct: 1421 --PPGEQGEKGD--RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA--KG 1474

Query: 522  PFNQGPPGAPPHAGGPPPHQYPP 544
                G P       GPP H  PP
Sbjct: 1475 ATGPGGPKGEKGVQGPPGHPGPP 1497



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 170/639 (26%), Positives = 213/639 (33%), Gaps = 136/639 (21%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPPGGGG--- 66
            GP    G  G  G +GG  P GPPG  +RG  GP G  G PG     GP  PPG  G   
Sbjct: 850  GPRGATGKSGAKGTSGGDGPHGPPG--ERGLPGPQGPNGFPG---PKGPPGPPGKDGLPG 904

Query: 67   -PGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQL-EDGDQPESKKLA 124
             PG R +               +G   A        + G  G      E G    + K  
Sbjct: 905  HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEG 964

Query: 125  SQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDS 184
            ++GD      GP   P +         P G  GL    GG  +   +  SG      P  
Sbjct: 965  TKGDP-----GPPGAPGKDGPAGLRGFP-GERGLPGTAGGPGLKGNEGPSG-----PPGP 1013

Query: 185  GGLP-ERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAG 243
             G P ER  + +G P         +      G  GPPG   +    G+ G +     P G
Sbjct: 1014 AGSPGERGAAGSGGP---------IGPPGRPGPQGPPGAAGEKGVPGEKGPIG----PTG 1060

Query: 244  KAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDIL 303
            + G V G  G     L   AG   +  +DG +          +GDP              
Sbjct: 1061 RDG-VQGPVG-----LPGPAGPPGVAGEDGDKGE--------VGDP-------------- 1092

Query: 304  RERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDG 363
                +G  G++ E+G     G   PV +       G  G   +  Q   G     K D+G
Sbjct: 1093 --GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG--ARGPQGHFGA----KGDEG 1144

Query: 364  T-------GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRG 416
            T       GP  +  + GP         +          GP GPPG PG P G  G    
Sbjct: 1145 TRGFNGPPGPIGLQGLPGPSGEKGETGDV----------GPMGPPGPPG-PRGPAGPNGA 1193

Query: 417  QGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFI 476
             G  GPPGG      P  K     G  GE+     Q               G+P  K   
Sbjct: 1194 DGPQGPPGGVGNLGPPGEK-----GEPGESGSPGIQ---------------GEPGVK--G 1231

Query: 477  IRGSPQQIDHAKQLIEEKIEGPLCPVG-PGP-GGPGPAGPMGPFNPGPFNQGPP------ 528
             RG   +   + Q  E    GP  P G  GP G PGP G   P +PGP  +G P      
Sbjct: 1232 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG--FPGDPGPPGEGGPRGQDGA 1289

Query: 529  -------GAPPHAGGPPP--HQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAY 579
                   G P   G P P     PP   G   P    P          A  DP A  A  
Sbjct: 1290 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS-PGSEGRQGGKGAKGDPGAIGAPG 1348

Query: 580  YSHYYQQPPGPV--PGPAPAPAAPPAQGEPPQPPPTGQS 616
             +     P GP   PGP      P + G+  +P  TGQ+
Sbjct: 1349 KTGPV-GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1386



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 199/748 (26%), Positives = 250/748 (33%), Gaps = 158/748 (21%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG------ 63
            PPGP  PAG  G  G  G    PGP   GD G  GP G     GS G P  PPG      
Sbjct: 400  PPGPEGPAGLIGPPGIQGN---PGP--VGDPGERGPPGRAGLPGSDGAPG-PPGTSLMLP 453

Query: 64   ---GGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120
               G G G +    A    +A+ I  +    A   +       G+ G+   L    QP S
Sbjct: 454  FRFGSGGGDKGPVVAAQEAQAQAILQQ----ARLALRGPPGPMGYTGRPGPL---GQPGS 506

Query: 121  KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI 180
              L  +    S  LGP  P     +T     P G  G     G +    +  D G K   
Sbjct: 507  PGLKGE----SGDLGPQGPRGPQGLTG----PPGKAGRRGRAGADGARGMPGDPGVKGDR 558

Query: 181  SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI 240
              D  GLP       G P      K    D  ++G  GPPG+  +  + G+ G  + +  
Sbjct: 559  GFD--GLP-------GLPGE----KGHRGDTGAQGLPGPPGEDGERGDDGEIGP-RGLPG 604

Query: 241  PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM 300
             +G  GL+  KG   I       G   +   DG Q      P   +G             
Sbjct: 605  ESGPRGLLGPKGPPGIP------GPPGVRGMDGPQG-----PKGSLGP------------ 641

Query: 301  DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ 360
                   QG  G   + G+   G   +P P+ +    IG  GE  K  Q   G+      
Sbjct: 642  -------QGEPGPPGQQGTP--GTQGLPGPQGA----IGPHGE--KGPQGKPGLPGMPGS 686

Query: 361  DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW 420
            D   GP       GPP    +             SGP GP G PG P G +G    +G  
Sbjct: 687  D---GPPGHPGKEGPPGTKGNQGP----------SGPQGPLGYPG-PRGVKGVDGIRGLK 732

Query: 421  GPPGGEMTFSIPTHK--CGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIR 478
            G  G +     P  K   G+   RG   V     + G      R   P GDP        
Sbjct: 733  GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGR-TGPTGDP-------- 783

Query: 479  GSPQQIDHAKQLIEEKI------EGPLCPVG----PGPGG----------PGPAGPMGPF 518
            G P  +    +L    +      +GP   +G    PG  G           GP G  GP 
Sbjct: 784  GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 843

Query: 519  NP----GPFN-QGPPGAPPHAGGPPPHQYP-------PQGWGNTYPQWQPPAPHDPSKAA 566
             P    GP    G  GA   +GG  PH  P       PQG  N +P   P  P  P    
Sbjct: 844  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG-PNGFP--GPKGPPGPPGKD 900

Query: 567  AAAADPNAAWAAYYSHYYQQPPGP--VPGPAPAPAAPPAQGEPPQP----PPTGQSDYTK 620
                 P       +      PPGP  V GP  A       GE   P    PP  Q     
Sbjct: 901  GLPGHPGQRGEVGFQG-KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 959

Query: 621  AWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE 680
            A +E  K     P  PGA P +D       +  ++    T GGPG      P      A 
Sbjct: 960  AGKEGTK---GDPGPPGA-PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 1015

Query: 681  YYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708
               ++ A      G GGP  PP + G Q
Sbjct: 1016 SPGERGA-----AGSGGPIGPPGRPGPQ 1038



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 207/824 (25%), Positives = 255/824 (30%), Gaps = 242/824 (29%)

Query: 8    GPP--PGPPPPAGGGGGAGGAGG-------GPP-----------PGPPGA-GDRGGGGPG 46
            GPP  PGPP   G  G  G  G        GPP           PGP GA G  G  GP 
Sbjct: 616  GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 675

Query: 47   G--GGPG-GGSAGGPSQPPGGGGPGIRKDAFADAVQ------RARQIAAKIGGDAATTVN 97
            G  G PG  GS G P  P   G PG + +      Q        R +    G        
Sbjct: 676  GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHK 735

Query: 98   NSTPDFGFGGQKRQL-EDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMV 156
                + GF G K  +   GD+ E     S+G+      GP  P  RT  T +     G  
Sbjct: 736  GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-----GPEGPKGRTGPTGD----PGPP 786

Query: 157  GLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAP-ESVQKAKMMLDDIVSRG 215
            GL+  +G   +  +    G +          P+ S+   G P  S +K    L      G
Sbjct: 787  GLMGEKGKLGVPGLPGYPGRQG---------PKGSLGFPGFPGASGEKGARGLS-----G 832

Query: 216  RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
            + GP G+       GQ G         GK+G     GG+         G+       G Q
Sbjct: 833  KSGPRGERGPTGPRGQRGP----RGATGKSGAKGTSGGDGPHGPPGERGL------PGPQ 882

Query: 276  NTN-VDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSV 334
              N    P    G P K             +   G  G R E G +  G    P P   V
Sbjct: 883  GPNGFPGPKGPPGPPGK-------------DGLPGHPGQRGEVGFQ--GKTGPPGPPGVV 927

Query: 335  GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394
            G   G +GE                    TGP       GPP              +  +
Sbjct: 928  GPQ-GAAGE--------------------TGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 966

Query: 395  SGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQ 452
              P GPPG PG   P G RG    +G  G  GG           GL   +G E       
Sbjct: 967  GDP-GPPGAPGKDGPAGLRGFPGERGLPGTAGGP----------GL---KGNEG------ 1006

Query: 453  QTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512
                         P+G P        GSP          E    G   P+GP PG PGP 
Sbjct: 1007 -------------PSGPPG-----PAGSPG---------ERGAAGSGGPIGP-PGRPGPQ 1038

Query: 513  GPMG-------PFNPGPFN-------QGPPGAPPHAGGP-------------PPHQYPPQ 545
            GP G       P   GP         QGP G P  AG P              P Q   +
Sbjct: 1039 GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 1098

Query: 546  GWGNTYPQWQPPAPHDP-SKAAAAAADPNAAWAAYYSHY----------YQQPPGPV--- 591
            G    +    PP P  P  +  AA AD          H+          +  PPGP+   
Sbjct: 1099 GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1158

Query: 592  --PGPA--------------PAPAAP-----PAQGEPPQPPPTGQSDYTKAWEE------ 624
              PGP+              P P  P     P   + PQ PP G  +     E+      
Sbjct: 1159 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1218

Query: 625  ------------------YYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGA 666
                                K    QP +PG PP        +        V   G PG 
Sbjct: 1219 GSPGIQGEPGVKGPRGERGEKGESGQPGEPG-PPGPKGPTGDDGPKGNPGPVGFPGDPG- 1276

Query: 667  PPGSQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQGQQ 708
            PPG         A+  R +    GQ  +PGP G   PP   G++
Sbjct: 1277 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 2/67 (2%)

Query: 3    DYSTGGPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60
            D    G P  PG P P G  G  G  G   P G PG+  R GG    G PG   A G + 
Sbjct: 1292 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1351

Query: 61   PPGGGGP 67
            P G  GP
Sbjct: 1352 PVGPAGP 1358



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 80/305 (26%), Positives = 107/305 (35%), Gaps = 45/305 (14%)

Query: 10   PPGPPPPAGGGGGAGGAG--GGP-PPGPPG-AGDRGGGGPGG-----GGPGGGSAGGPSQ 60
            PPGP  P G  G  G  G  G P  PGPPG  G RG  G  G     G PG   + GP+ 
Sbjct: 1250 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1309

Query: 61   PPGGGGPGIRKDAFADAVQRARQIAAKIGGD--AATTVNNSTPDFGFGGQKRQLEDGDQP 118
              G  GP  ++          RQ      GD  A      + P    G   +   DG + 
Sbjct: 1310 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1369

Query: 119  ESKKLASQG----DSISSQLGPIHPPPRTSM-----TEEYRVPDGMVGLIIGRGGEQINK 169
                +  QG       +   GP+ PP    +      +  +   G++GL IG  GEQ  K
Sbjct: 1370 LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL-IGPPGEQGEK 1428

Query: 170  IQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANG 229
                 G +    P      +  + + GA   +             G GGPPG        
Sbjct: 1429 -----GDRGLPGPQGSPGQKGEMGIPGASGPI-------------GPGGPPGLPGPAGPK 1470

Query: 230  GQNGTVQEIMIPAGKAGLV-----IGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLR 284
            G  G       P G+ G+       G  GE I+ L  +   K     DGS+    D+ + 
Sbjct: 1471 GAKGATGP-GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1529

Query: 285  IIGDP 289
              G P
Sbjct: 1530 TGGAP 1534



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/133 (30%), Positives = 50/133 (37%), Gaps = 22/133 (16%)

Query: 495 IEGPLCPVGP----GP----GGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQG 546
           +EGP  P GP    GP    G PGP G  G   P P   G PG+    G P      P  
Sbjct: 397 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-PGRAGLPGSDGAPGPPGTSLMLPFR 455

Query: 547 WGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAP 601
           +G+      P      ++A A       A         + PPGP+     PGP   P +P
Sbjct: 456 FGSGGGDKGPVVAAQEAQAQAILQQARLA--------LRGPPGPMGYTGRPGPLGQPGSP 507

Query: 602 PAQGEPPQPPPTG 614
             +GE     P G
Sbjct: 508 GLKGESGDLGPQG 520



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 33/85 (38%), Positives = 35/85 (41%), Gaps = 20/85 (23%)

Query: 3    DYSTGGP--PPGPPPPAGGGGG------AGGAGGGPPPGPPGAGDRGG-----GGPGGGG 49
            D    GP  PPGP  PAG  G        GG G   PPG  G     G     G PG  G
Sbjct: 1172 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1231

Query: 50   PGG-----GSAGGPSQ--PPGGGGP 67
            P G     G +G P +  PPG  GP
Sbjct: 1232 PRGERGEKGESGQPGEPGPPGPKGP 1256



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 47/164 (28%), Positives = 59/164 (35%), Gaps = 45/164 (27%)

Query: 393 LRSGPPGPPGGPGM--------------------PPGGRGRGRGQGNWGPPGGEMTFSIP 432
           L  GPPGP G  G+                    PPG  G     G  GPPG  +     
Sbjct: 396 LVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPF- 454

Query: 433 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIE 492
             + G   G  G  V A   Q  A ++ +R              +RG P  + +  +   
Sbjct: 455 --RFGSGGGDKGPVVAAQEAQAQAILQQAR------------LALRGPPGPMGYTGR--- 497

Query: 493 EKIEGPLCPVGPGPGGPGPAGPMGPFNP-GPFNQGPPGAPPHAG 535
               GPL   G  PG  G +G +GP  P GP  QG  G P  AG
Sbjct: 498 ---PGPLGQPG-SPGLKGESGDLGPQGPRGP--QGLTGPPGKAG 535



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

Query: 5    STGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGG--GGPGGGSAGGPSQPP 62
            ++G   PG PP   G  G  GA G   PG P  G++G  GP G  G PG      P Q P
Sbjct: 1451 ASGPIGPGGPPGLPGPAGPKGAKGATGPGGP-KGEKGVQGPPGHPGPPGEVIQPLPIQMP 1509



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 5/34 (14%)

Query: 396  GPPGPPG-----GPGMPPGGRGRGRGQGNWGPPG 424
            GP GP G     GPG P G +G     G+ GPPG
Sbjct: 1465 GPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1498


>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
          Length = 356

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 89/350 (25%), Positives = 149/350 (42%), Gaps = 37/350 (10%)

Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
           VG IIG+ GE + +I+++SG ++ IS   G  PER ++LTG   ++ KA  M+ D +   
Sbjct: 25  VGSIIGKKGESVKRIREESGARINIS--EGNCPERIITLTGPTNAIFKAFAMIIDKLEED 82

Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
                    ++    +      +++PA + G +IGKGG  IK+++E  G ++ +  D   
Sbjct: 83  INS---SMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139

Query: 276 NTNVDKPLRIIGDPYK----VQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPR 331
           N + ++ + I G P      V+Q C ++++ L +  QG          R+      P+P 
Sbjct: 140 N-STERAITIAGVPQSVTECVKQICLVMLETLSQSPQG----------RVMTIPYQPMPA 188

Query: 332 HSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIA------HIMGPPDRCEHAARI 385
            S  +  G       +  + AG        D  GP   A      H + P D  +     
Sbjct: 189 SSPVICAGGQ----DRCSDAAG--YPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVA 242

Query: 386 INDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGE 445
                 ++  G  G  G     P  +G             E+T  IP +  G +IGR G 
Sbjct: 243 RQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELT--IPNNLIGCIIGRQGA 300

Query: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
           N+  I Q +GA ++I+   P  G    +   I GS   I  A+ LI  ++
Sbjct: 301 NINEIRQMSGAQIKIAN--PVEGSSG-RQVTITGSAASISLAQYLINARL 347



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 59/222 (26%), Positives = 90/222 (40%), Gaps = 29/222 (13%)

Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
           VG +IG+ GE +K+I+ ++G RI   +  G  PE+I  + GP +    A  +I D L+  
Sbjct: 25  VGSIIGKKGESVKRIREESGARINISE--GNCPERIITLTGPTNAIFKAFAMIIDKLEED 82

Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            +           PP                  +   +P  +CG +IG+GG  +K I + 
Sbjct: 83  INSSMTNSTAASRPPV----------------TLRLVVPATQCGSLIGKGGCKIKEIRES 126

Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQ-----LIEEKIEGPLCPVGPGPGG 508
           TGA V+++  + PN     +   I G PQ +    +     ++E   + P   V   P  
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQ 184

Query: 509 PGPAGPMGPFNPGPFNQGPPGAPPHA----GGPPPHQYPPQG 546
           P PA        G          PHA     GPP   Y  QG
Sbjct: 185 PMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQG 226



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 26/75 (34%), Positives = 46/75 (61%)

Query: 143 TSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQ 202
           T  T E  +P+ ++G IIGR G  IN+I+Q SG +++I+    G   R V++TG+  S+ 
Sbjct: 278 TQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASIS 337

Query: 203 KAKMMLDDIVSRGRG 217
            A+ +++  +S  +G
Sbjct: 338 LAQYLINARLSSEKG 352



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 51/197 (25%), Positives = 89/197 (45%), Gaps = 18/197 (9%)

Query: 230 GQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGD 288
           G N T+   ++  GK  G +IGK GE++K+++E +G ++ +    S+    ++ + + G 
Sbjct: 9   GLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI----SEGNCPERIITLTGP 64

Query: 289 PYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKI 348
              + +A  M++D L E D       +   SR    + + VP    G +IG+ G  IK+I
Sbjct: 65  TNAIFKAFAMIIDKL-EEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEI 123

Query: 349 QNDAGVRIQFKQDD-GTGPEKIAHIMGPPDR-CEHAARIINDLLQSLRSGPPG------- 399
           +   G ++Q   D      E+   I G P    E   +I   +L++L   P G       
Sbjct: 124 RESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPY 183

Query: 400 ---PPGGPGMPPGGRGR 413
              P   P +  GG+ R
Sbjct: 184 QPMPASSPVICAGGQDR 200



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 63/287 (21%), Positives = 109/287 (37%), Gaps = 40/287 (13%)

Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
           + I+S +       R  +T    VP    G +IG+GG +I +I++ +G +VQ++ D   L
Sbjct: 81  EDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138

Query: 188 P---ERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGK 244
           P   ER++++ G P+SV +    +  ++       P         G+  T+    +PA  
Sbjct: 139 PNSTERAITIAGVPQSVTECVKQICLVMLETLSQSP--------QGRVMTIPYQPMPASS 190

Query: 245 AGLVIGKGGETIKQLQERAGVKMI--------LIQDGSQNTNVDKPLRIIGDPYKVQQAC 296
              VI  GG+   +  + AG            L     Q  +   PL    D  K+ Q  
Sbjct: 191 P--VICAGGQ--DRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPL----DLAKLNQVA 242

Query: 297 EMVMDILRERDQGGFGDRNEYGSRIGG-----------GIDVPVPRHSVGVVIGRSGEMI 345
                        GF   +     + G             ++ +P + +G +IGR G  I
Sbjct: 243 RQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANI 302

Query: 346 KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQS 392
            +I+  +G +I+          +   I G       A  +IN  L S
Sbjct: 303 NEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSS 349


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 180/669 (26%), Positives = 221/669 (33%), Gaps = 171/669 (25%)

Query: 11  PGPPPPAGGGGGAGGAGGGPPPGP---------PGA----------GDRGGGGPGG---- 47
           PG P PAG  G  G  G   PPGP         PGA          G RG  GP G    
Sbjct: 313 PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGE 372

Query: 48  -GGPGGGSAGGPSQPPGGGG-PGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGF 105
            G PG   A GP+  PG  G PG      A     A  IA   G   A   +      G 
Sbjct: 373 PGPPGPAGAAGPAGNPGADGQPG------AKGANGAPGIAGAPGFPGARGPSGPQGPGGP 426

Query: 106 GGQKRQLEDGDQPESKKLASQGDS-ISSQLGP--IHPPPRTSMTEEYR------VPDGMV 156
            G K     G+  E     S+GD+    + GP  +  PP  +  E  R       P G+ 
Sbjct: 427 PGPK-----GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLP 481

Query: 157 GLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGR 216
           G    RGG                 P S G P          + V   K    +  S G 
Sbjct: 482 GPPGERGG-----------------PGSRGFP--------GADGVAGPKGPAGERGSPGP 516

Query: 217 GGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN 276
            GP G      + G+ G   E  +P  K GL    G         + G      QDG   
Sbjct: 517 AGPKG------SPGEAGRPGEAGLPGAK-GLT---GSPGSPGPDGKTGPPGPAGQDGRPG 566

Query: 277 TNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGV 336
                     G P    QA  M         +G  G+  + G R      VP P  +VG 
Sbjct: 567 PP--------GPPGARGQAGVMGF----PGPKGAAGEPGKAGER-----GVPGPPGAVGP 609

Query: 337 VIGRSGEMIKK----IQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAAR--IINDLL 390
             G+ GE   +        AG R +       G + +    GPP          +  DL 
Sbjct: 610 A-GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDL- 667

Query: 391 QSLRSGPPGPPG--------------GPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKC 436
                G PGP G              GP  P G RG     GN G  G       P    
Sbjct: 668 -----GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPG--- 719

Query: 437 GLVIGRGGENVKAINQQTGAFVEISRQLP-PNGDPNFKLFIIRGSPQQIDHAKQLIEEK- 494
                +G   ++ +  + GA       LP P GD           P+  D +      + 
Sbjct: 720 ----SQGAPGLQGMPGERGA-----AGLPGPKGDRG------DAGPKGADGSPGKDGVRG 764

Query: 495 IEGPLCPVGP--GPGGPGPAGPMGPFNP-----GPFNQGPPGAPPHAGGPPPHQYPPQGW 547
           + GP+ P GP   PG  G +GP GP  P      P ++G PG P    GP     PP   
Sbjct: 765 LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP----GPAGFAGPPGAD 820

Query: 548 GNTYPQWQPPAPHDPSKAAAA--AADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQG 605
           G      QP A  +P  A A   A  P  A  A        PPGP+ G   AP A  A+G
Sbjct: 821 G------QPGAKGEPGDAGAKGDAGPPGPAGPA-------GPPGPI-GNVGAPGAKGARG 866

Query: 606 EPPQPPPTG 614
               P  TG
Sbjct: 867 SAGPPGATG 875



 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 195/753 (25%), Positives = 223/753 (29%), Gaps = 140/753 (18%)

Query: 10  PPGPPPPAGGGGGA---GGAGGGPPPGPPGA-------------------------GDRG 41
           PPGPP   G  G A   G  G   PPGP GA                         GD G
Sbjct: 222 PPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAG 281

Query: 42  GGGPGG--GGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNS 99
             GP G  G PG   A G   P G  G   R  A   A  R    A    G    T    
Sbjct: 282 PAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAG 341

Query: 100 TPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLI 159
            P F  G    + E G Q        QG  +  + GP  P             DG  G  
Sbjct: 342 PPGFP-GAVGAKGEAGPQGPRGSEGPQG--VRGEPGPPGPAGAAGPAGNPGA-DGQPGAK 397

Query: 160 IGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGR--- 216
              G   I       G +    P   G P      +G P     A     D  ++G    
Sbjct: 398 GANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEP----GAPGSKGDTGAKGEPGP 453

Query: 217 ---GGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDG 273
               GPPG   +    G  G      +P G  G   G G          AG K    + G
Sbjct: 454 VGVQGPPGPAGEEGKRGARGEPGPTGLP-GPPGERGGPGSRGFPGADGVAGPKGPAGERG 512

Query: 274 SQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHS 333
           S       P    G P +            R  + G  G +   GS    G D       
Sbjct: 513 SPG-----PAGPKGSPGEAG----------RPGEAGLPGAKGLTGSPGSPGPDGKTGPPG 557

Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
                GR G          G R Q       GP+  A   G P +               
Sbjct: 558 PAGQDGRPGP-----PGPPGARGQAGVMGFPGPKGAA---GEPGKAG------------- 596

Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGP--PGGEMTFSIPTHKCGL-----VIGRGGEN 446
             G PGPPG  G P G  G    QG  GP  P GE     P    G        G  GE 
Sbjct: 597 ERGVPGPPGAVG-PAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655

Query: 447 VKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP-- 504
            K   Q     +         G+        RG P          E  ++GP  P GP  
Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGE--------RGFPG---------ERGVQGPPGPAGPRG 698

Query: 505 ---GPGGPGPAGPMG-PFNPG----PFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQP 556
               PG  G  G  G P  PG    P  QG PG    AG P     P    G+  P+   
Sbjct: 699 ANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPG----PKGDRGDAGPKGAD 754

Query: 557 PAP-HDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQ 615
            +P  D  +       P     A        P GP  GP  A  AP  +GEP  P P G 
Sbjct: 755 GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA-GPTGARGAPGDRGEPGPPGPAGF 813

Query: 616 SDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYS 675
           +    A             QPGA  +     A     K  A      GP  PPG   +  
Sbjct: 814 AGPPGA-----------DGQPGAKGEPGDAGA-----KGDAGPPGPAGPAGPPGPIGNVG 857

Query: 676 AAWAEYYRQQAAYYGQT--PGPGGPQPPPTQQG 706
           A  A+  R  A   G T  PG  G   PP   G
Sbjct: 858 APGAKGARGSAGPPGATGFPGAAGRVGPPGPSG 890



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 184/738 (24%), Positives = 223/738 (30%), Gaps = 167/738 (22%)

Query: 6    TGGP-PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQ 60
            TG P  PGP    G  G AG  G   PPGPPGA  + G  G PG  G  G  G AG    
Sbjct: 541  TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGV 600

Query: 61   PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES 120
            P   G PG    A  D    A+      G              GF G       G   E+
Sbjct: 601  P---GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA--GPPGEA 655

Query: 121  KKLASQGDSISSQLGPIHPPPRTSMTEE-------YRVPDGMVGLIIGRGGEQINKIQQD 173
             K   QG  +   LG   P P  +  E         + P G  G     G    +  + D
Sbjct: 656  GKPGEQG--VPGDLGA--PGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGD 711

Query: 174  SGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNG 233
            +G     +P S G P     L G P               RG  G PG   D  + G   
Sbjct: 712  AGAPG--APGSQGAP----GLQGMPGE-------------RGAAGLPGPKGDRGDAG--- 749

Query: 234  TVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQ 293
                   P G  G     G + ++ L    G        G      DK       P    
Sbjct: 750  -------PKGADG---SPGKDGVRGLTGPIG------PPGPAGAPGDKGESGPSGPAGPT 793

Query: 294  QACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAG 353
             A            +G  GDR E G     G   P          G  G        DAG
Sbjct: 794  GA------------RGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG--------DAG 833

Query: 354  VRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGM--PPGGR 411
             +         GP   A   GPP    +              G PG  G  G   PPG  
Sbjct: 834  AK------GDAGPPGPAGPAGPPGPIGNV-------------GAPGAKGARGSAGPPGAT 874

Query: 412  GRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPN 471
            G     G  GPPG       P    G     GG+  +      G   E+    PP     
Sbjct: 875  GFPGAAGRVGPPGPSGNAG-PPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGE 933

Query: 472  FKLFIIRGSPQQIDHAKQLIEEKIEGPL-CPVGPGPGG----------PGPAGPMG-PFN 519
                  +GSP              +GP   P  PGP G          PG  G  G P  
Sbjct: 934  ------KGSPGA------------DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL 975

Query: 520  PGPFN----QGPPGA-----PPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAA 570
            PGP      QGP GA     PP   GPP    PP   G +  +  P A   P +  +  A
Sbjct: 976  PGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPP---GESGREGAPGAEGSPGRDGSPGA 1032

Query: 571  DPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIG 630
              +             P GP PG   AP AP   G   +    G++              
Sbjct: 1033 KGDRGETG--------PAGP-PGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGA 1083

Query: 631  QQPQQPGAP--PQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAY 688
            + P  P  P   + +  +  +   K     +   GP  PPGS  +   + A         
Sbjct: 1084 RGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGAS-------- 1135

Query: 689  YGQTPGPGGPQPPPTQQG 706
                 GP GP+ PP   G
Sbjct: 1136 -----GPAGPRGPPGSAG 1148



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 198/778 (25%), Positives = 260/778 (33%), Gaps = 142/778 (18%)

Query: 8    GPPPGPP-----PPAGGGGGAGGAGGGPPP----GPPGAGDRGGGGPGGGGPGGGSAGGP 58
            G PPGP      P A G  G  GA G P P    GPPG     G     G P  G  G P
Sbjct: 424  GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP--GPTGLP 481

Query: 59   SQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQP 118
              P   GGPG R    AD V   +  A + G         S  + G  G      +   P
Sbjct: 482  GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPG------EAGLP 535

Query: 119  ESKKLASQGDSISSQLGPIHP--PPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGC 176
             +K L     S     GP     PP  +  +    P G  G    RG   +       G 
Sbjct: 536  GAKGLTGSPGS----PGPDGKTGPPGPAGQDGRPGPPGPPG---ARGQAGVMGFPGPKGA 588

Query: 177  KVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGT-- 234
                + + G   ER V   G P +V  A     +  ++G  GP G   +    G  G+  
Sbjct: 589  ----AGEPGKAGERGV--PGPPGAVGPAGKD-GEAGAQGPPGPAGPAGERGEQGPAGSPG 641

Query: 235  VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQ 294
             Q +  PAG  G   GK GE  + +    G        G +    ++ ++    P   + 
Sbjct: 642  FQGLPGPAGPPG-EAGKPGE--QGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRG 698

Query: 295  ACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGV 354
            A     +   + D G  G     G+   G   +P  R + G+  G  G+     + DAG 
Sbjct: 699  ANGAPGNDGAKGDAGAPGAPGSQGA--PGLQGMPGERGAAGLP-GPKGD-----RGDAGP 750

Query: 355  RIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGP---------------PG 399
            +         G   +   +GPP      A    D  +S  SGP               PG
Sbjct: 751  KGADGSPGKDGVRGLTGPIGPPG----PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPG 806

Query: 400  PPGGPGM--PPGGRGR---------GRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGEN 446
            PPG  G   PPG  G+            +G+ GPPG  G      P    G    +G   
Sbjct: 807  PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARG 866

Query: 447  VKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGP 506
                   TG      R  PP    N       G P     A    +E  +GP    GP  
Sbjct: 867  SAGPPGATGFPGAAGRVGPPGPSGN------AGPPGPPGPAG---KEGGKGPRGETGPA- 916

Query: 507  GGPGPAGPMGPFNPGPFNQ-GPPGAPPHAGGP--PPHQ----------YPPQGWGNTYPQ 553
            G PG  GP GP  PGP  + G PGA   AG P  P  Q           P Q     +P 
Sbjct: 917  GRPGEVGPPGP--PGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974

Query: 554  WQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV--------PGPAPAPAAPPAQG 605
               P+  +P K   + A              + PPGP+        PG +    AP A+G
Sbjct: 975  LPGPS-GEPGKQGPSGASGE-----------RGPPGPMGPPGLAGPPGESGREGAPGAEG 1022

Query: 606  EPPQP-PPTGQSDYTKAWEEYYKKIGQQPQQPGAP----PQQDYTKAWEEYYKKQAQVA- 659
             P +   P  + D  +            P  PGAP    P     K+ +      A  A 
Sbjct: 1023 SPGRDGSPGAKGDRGETGP------AGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAG 1076

Query: 660  -----TGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQT--PGPGGPQPPPTQQGQQQA 710
                    GP  P G + D      +  R    + G +   GP GP   P +QG   A
Sbjct: 1077 PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGA 1134



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 101/327 (30%), Positives = 116/327 (35%), Gaps = 56/327 (17%)

Query: 396 GPPGPPGGPGMPPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
           GP GP G PG PPG  G    QG  GPPG  GE   S P    G   G  G+N    + +
Sbjct: 182 GPSGPRGLPG-PPGAPGP---QGFQGPPGEPGEPGASGPMGPRG-PPGPPGKN--GDDGE 234

Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP--GPGGPGP 511
            G       + PP       L    G P    H      +  +G   P GP   PG PG 
Sbjct: 235 AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGE 294

Query: 512 AGPMGPFNPG--PFNQGPPGAPPHAG-----GPPPHQYPPQGWGNTYPQWQPPAPHDPSK 564
            G  G   P   P  +G PGAP  AG     G      PP   G T P   P  P   + 
Sbjct: 295 NGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP---GPTGPAGPPGFP--GAV 349

Query: 565 AAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPA--PAA-PPAQGEPPQPPPTGQSDYTKA 621
            A   A P     +      +  PGP PGPA A  PA  P A G+P      G      A
Sbjct: 350 GAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA 408

Query: 622 WEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEY 681
                 +    PQ PG PP                     G PGA PGS+ D  A     
Sbjct: 409 PGFPGARGPSGPQGPGGPP---------------GPKGNSGEPGA-PGSKGDTGAK---- 448

Query: 682 YRQQAAYYGQTPGPGGPQPPPTQQGQQ 708
                      PGP G Q PP   G++
Sbjct: 449 ---------GEPGPVGVQGPPGPAGEE 466



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 72/242 (29%), Positives = 81/242 (33%), Gaps = 64/242 (26%)

Query: 396  GPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            GPPGP G PG+  PPG  GR    G  G PG +                G    K    +
Sbjct: 995  GPPGPMGPPGLAGPPGESGREGAPGAEGSPGRD----------------GSPGAKGDRGE 1038

Query: 454  TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP-GP-GGPGP 511
            TG          P G P        G+P  +  A +  +    GP  P GP GP G  GP
Sbjct: 1039 TGP-------AGPPGAPGAP-----GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGP 1086

Query: 512  AGPMGPFNPG--PFNQGPPGAPPHAG-----GPPPHQYPPQGWGNTYPQWQ--PPAPHDP 562
            AGP GP         QG  G   H G     GPP    PP   G   P     P  P  P
Sbjct: 1087 AGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPG---PPGSPGEQGPSGASGPAGPRGP 1143

Query: 563  SKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAP----------APAAPPAQGEPPQPPP 612
              +A A                   PGP+  P P           P  PP    PP PP 
Sbjct: 1144 PGSAGAPGKDGLNGL----------PGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPS 1193

Query: 613  TG 614
             G
Sbjct: 1194 AG 1195



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 97/359 (27%), Positives = 115/359 (32%), Gaps = 69/359 (19%)

Query: 396  GPPGP-----------PGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGG 444
            GPPGP           P GP  P G RG    +G  GPPG       P    G     G 
Sbjct: 770  GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPG-------PAGFAGPPGADGQ 822

Query: 445  ENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP 504
               K      GA  +     P             G P  I +      +   G   P G 
Sbjct: 823  PGAKGEPGDAGAKGDAGPPGPAGP---------AGPPGPIGNVGAPGAKGARGSAGPPG- 872

Query: 505  GPGGPGPAGPMGPFNPGPF-NQGPPGAPPHAG-----GPPPHQYPPQGWGNTYPQWQP-P 557
              G PG AG +GP  PGP  N GPPG P  AG     GP     P    G   P   P P
Sbjct: 873  ATGFPGAAGRVGP--PGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP 930

Query: 558  APHDPSKAA----AAAADPNAAWAAYYSHYYQQP--------PGPVPGPAPAPAAPP--- 602
            A    S  A     A   P     A        P        PG +PGP+  P       
Sbjct: 931  AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG-LPGPSGEPGKQGPSG 989

Query: 603  AQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG 662
            A GE   P P G         E  ++    P   G+P +     A  +    + +    G
Sbjct: 990  ASGERGPPGPMGPPGLAGPPGESGRE--GAPGAEGSPGRDGSPGAKGD----RGETGPAG 1043

Query: 663  GPGAP--PGSQPDYSAAWAEYYRQQAAYYGQTP--------GPGGPQPPPTQQGQQQAQ 711
             PGAP  PG+      A     R +    G           GP GPQ P   +G+   Q
Sbjct: 1044 PPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQ 1102



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 67/226 (29%), Positives = 73/226 (32%), Gaps = 68/226 (30%)

Query: 395  SGPPGPPGGPGM-----PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKA 449
            +GP GPPG PG      P G  G+   +G  GP G       P    G V  RG    + 
Sbjct: 1039 TGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAG-------PAGPVGPVGARGPAGPQG 1091

Query: 450  INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGP 509
                 G   E        GD   K    RG                 G   P GP PG P
Sbjct: 1092 PRGDKGETGE-------QGDRGIKGH--RG---------------FSGLQGPPGP-PGSP 1126

Query: 510  GPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAA 569
            G  GP G   P     GP G P  AG P        G         PP P   +  A   
Sbjct: 1127 GEQGPSGASGPA----GPRGPPGSAGAP-----GKDGLNGLPGPIGPPGPRGRTGDAGPV 1177

Query: 570  ADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEP----PQPP 611
                             PPGP PGP P P  PP+ G      PQPP
Sbjct: 1178 G----------------PPGP-PGP-PGPPGPPSAGFDFSFLPQPP 1205



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 145/581 (24%), Positives = 183/581 (31%), Gaps = 91/581 (15%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPSQP-----PG-G 64
            G P P+G  G  G  G     GPPG AG RG  G  G     G AG P  P     PG  
Sbjct: 668  GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQ 727

Query: 65   GGPGIRKDAFADAVQRARQIAAKIGGDAATT---VNNSTPDFGFGGQKRQLEDGDQPESK 121
            G PG R  A     +  R  A   G D +     V   T   G  G       GD+ ES 
Sbjct: 728  GMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGA--PGDKGESG 785

Query: 122  KLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQIS 181
                 G + +         P       +  P G  G    +G       + D+G      
Sbjct: 786  PSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAG 845

Query: 182  PDSGGLPERSVSLTGAPESVQKAKM--MLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIM 239
            P     P  +V   GA  +   A          + GR GPPG    + N G  G      
Sbjct: 846  PAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGP---SGNAGPPG------ 896

Query: 240  IPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ----NTNVDKPLRIIGDPYKVQQA 295
             P G AG   GKG         R G        G      +   D P    G P     A
Sbjct: 897  -PPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIA 955

Query: 296  CEM-VMDILRERDQGGF-------GDRNEYG-SRIGGGIDVPVPRHSVGVVIGRSGEMIK 346
             +  V+ +  +R + GF       G+  + G S   G    P P    G+  G  GE   
Sbjct: 956  GQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA-GPPGE--- 1011

Query: 347  KIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGM 406
                             +G E      G P R + +     D  ++  +GPPG PG PG 
Sbjct: 1012 -----------------SGREGAPGAEGSPGR-DGSPGAKGDRGETGPAGPPGAPGAPGA 1053

Query: 407  P----PGGRGRGRGQ-------------------------GNWGPPGGEMTFSIPTHK-- 435
            P    P G+   RG+                         G+ G  G +    I  H+  
Sbjct: 1054 PGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGF 1113

Query: 436  CGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
             GL    G          +GA      + PP          + G P  I           
Sbjct: 1114 SGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD 1173

Query: 496  EGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGG 536
             GP+ P GP PG PGP GP        F   PP    H GG
Sbjct: 1174 AGPVGPPGP-PGPPGPPGPPSAGFDFSFLPQPPQEKAHDGG 1213



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 97/366 (26%), Positives = 112/366 (30%), Gaps = 71/366 (19%)

Query: 396 GPPGPPGGPGM--------------PPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKC 436
           GPPG  GGPG               P G RG     G  G PG     GE    +P  K 
Sbjct: 482 GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEA--GLPGAK- 538

Query: 437 GLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFK----LFIIRGSPQQIDHAKQLIE 492
           GL    G           G   +  R  PP G P  +    +    G         +  E
Sbjct: 539 GLTGSPGSPGPDGKTGPPGPAGQDGRPGPP-GPPGARGQAGVMGFPGPKGAAGEPGKAGE 597

Query: 493 EKIEGPLCPVGP--------GPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPP 544
             + GP   VGP          G PGPAGP G        QGP G+P   G P P   PP
Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG----EQGPAGSPGFQGLPGP-AGPP 652

Query: 545 QGWGNTYPQWQP---PAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGP----------- 590
              G    Q  P    AP  PS A      P            Q PPGP           
Sbjct: 653 GEAGKPGEQGVPGDLGAP-GPSGARGERGFPG-------ERGVQGPPGPAGPRGANGAPG 704

Query: 591 ---VPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKA 647
                G A AP AP +QG P      G+            +    P+     P +D  + 
Sbjct: 705 NDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG 764

Query: 648 WEEYYKKQAQVATGG--GPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQ 705
                         G  G   P G      A  A   R +       PGP G   PP   
Sbjct: 765 LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPG----PPGPAGFAGPPGAD 820

Query: 706 GQQQAQ 711
           GQ  A+
Sbjct: 821 GQPGAK 826



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 31/70 (44%), Positives = 34/70 (48%), Gaps = 12/70 (17%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG-----GGPGGGGPGG-----GSAG--G 57
            PPGPP   G  G +G +G   P GPPG+    G     G PG  GP G     G AG  G
Sbjct: 1119 PPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVG 1178

Query: 58   PSQPPGGGGP 67
            P  PPG  GP
Sbjct: 1179 PPGPPGPPGP 1188



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 27/66 (40%), Positives = 27/66 (40%), Gaps = 2/66 (3%)

Query: 3   DYSTGGP--PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ 60
           D    GP  P GPP P G  G  G  G     GPPGA    G     G PG     GP  
Sbjct: 837 DAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPG 896

Query: 61  PPGGGG 66
           PPG  G
Sbjct: 897 PPGPAG 902



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 36/78 (46%), Positives = 38/78 (48%), Gaps = 14/78 (17%)

Query: 5   STGG-PPPGPPPPAGGGG-----GAGGAGG--GPP--PGPPGA----GDRGGGGPGGGGP 50
           STGG   PGP  P+G  G     GA G  G  GPP  PG PGA    G RG  GP G   
Sbjct: 171 STGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNG 230

Query: 51  GGGSAGGPSQPPGGGGPG 68
             G AG P +P   G PG
Sbjct: 231 DDGEAGKPGRPGERGPPG 248



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 86/340 (25%), Positives = 105/340 (30%), Gaps = 98/340 (28%)

Query: 395 SGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQT 454
           +GPPGP G P  PPG  G    +G  GP G                 RG E  + +  + 
Sbjct: 331 AGPPGPTG-PAGPPGFPGAVGAKGEAGPQGP----------------RGSEGPQGVRGEP 373

Query: 455 GAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGP 514
           G     +    P G+P        G P            K       +   PG PG  GP
Sbjct: 374 GP-PGPAGAAGPAGNPGAD-----GQPGA----------KGANGAPGIAGAPGFPGARGP 417

Query: 515 MGPFNPG-----PFNQGPPGAPPHAG--------GPPPHQYPP---QGWGNTYPQWQP-- 556
            GP  PG       N G PGAP   G        GP   Q PP      G    + +P  
Sbjct: 418 SGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGP 477

Query: 557 ---PAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPV-----PGPAPAPAAPPAQGEPP 608
              P P        +   P A   A        P GP      PGPA    +P   G P 
Sbjct: 478 TGLPGPPGERGGPGSRGFPGADGVA-------GPKGPAGERGSPGPAGPKGSPGEAGRPG 530

Query: 609 QPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPP 668
           +    G    T +              PG+P     T          A      GP  PP
Sbjct: 531 EAGLPGAKGLTGS--------------PGSPGPDGKTGP-----PGPAGQDGRPGPPGPP 571

Query: 669 GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708
           G+            R QA   G  PGP G    P + G++
Sbjct: 572 GA------------RGQAGVMG-FPGPKGAAGEPGKAGER 598



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 31/68 (45%), Positives = 32/68 (47%), Gaps = 7/68 (10%)

Query: 7   GGPPP----GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPSQP 61
           G P P    GPP PAG  G  G  G   P G PG  G+RGG G   G PG     GP  P
Sbjct: 449 GEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPG-SRGFPGADGVAGPKGP 507

Query: 62  PG-GGGPG 68
            G  G PG
Sbjct: 508 AGERGSPG 515



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 46/134 (34%), Positives = 50/134 (37%), Gaps = 22/134 (16%)

Query: 495 IEGPLCPVGPGPGGPGPAGPMG----PFNPG-PFNQGPPG--APPHAGGPPPHQ----YP 543
           +EGP    GP  G  GPAGP G    P  PG P   GPPG   PP  GG    Q    Y 
Sbjct: 110 VEGPKGDTGPR-GPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYD 168

Query: 544 PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPA 603
            +  G        P P  PS        P A         +Q PPG  PG  P  + P  
Sbjct: 169 EKSTGGI----SVPGPMGPSGPRGLPGPPGAPG----PQGFQGPPGE-PG-EPGASGPMG 218

Query: 604 QGEPPQPPPTGQSD 617
              PP PP     D
Sbjct: 219 PRGPPGPPGKNGDD 232



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 31/82 (37%), Positives = 33/82 (40%), Gaps = 25/82 (30%)

Query: 10  PPGPPPPAGGGGG----------------------AGGAGGGPPPGPPGA-GDRGGGGPG 46
           PPGPP P G GG                        G +G    PGPPGA G +G  GP 
Sbjct: 146 PPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPP 205

Query: 47  G--GGPGGGSAGGPSQPPGGGG 66
           G  G PG     GP  PPG  G
Sbjct: 206 GEPGEPGASGPMGPRGPPGPPG 227



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 26/67 (38%), Positives = 28/67 (41%), Gaps = 6/67 (8%)

Query: 8   GPPPGPPP-----PAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPP 62
           GPP  P P     P G  G  G +G   P GPPG   + G     G PG     GP  P 
Sbjct: 191 GPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQ 250

Query: 63  GGGG-PG 68
           G  G PG
Sbjct: 251 GARGLPG 257



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/56 (42%), Positives = 24/56 (42%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGG 65
            P GPP  AG  G  G  G   P GPPG   R G     G PG     GP  PP  G
Sbjct: 1140 PRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 34/99 (34%), Positives = 40/99 (40%), Gaps = 11/99 (11%)

Query: 10  PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGG----PGGGGPGGGSAGGPSQPPGG 64
           PPG P   G  G  G  G   PPGPPG  GD G  G    PG  GP  G  G    P   
Sbjct: 204 PPGEPGEPGASGPMGPRG---PPGPPGKNGDDGEAGKPGRPGERGP-PGPQGARGLPGTA 259

Query: 65  GGPGIRKDAFADAVQRARQIAAKIG--GDAATTVNNSTP 101
           G PG++       +  A+  A   G  G+  +   N  P
Sbjct: 260 GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP 298



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 30/76 (39%), Positives = 32/76 (42%), Gaps = 19/76 (25%)

Query: 11  PGPPPPAG--GGGGAGG--------------AGGGPPPGPPG-AGDRGGGGPGGGGPGGG 53
           PGPP P G  G  G GG               GG   PGP G +G RG  GP G     G
Sbjct: 141 PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQG 200

Query: 54  SAGGPSQP--PGGGGP 67
             G P +P  PG  GP
Sbjct: 201 FQGPPGEPGEPGASGP 216



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 27/75 (36%), Positives = 29/75 (38%), Gaps = 16/75 (21%)

Query: 10   PPGPPPPAGGGGGAGGAGGGP------------PPGPPGA----GDRGGGGPGGGGPGGG 53
            P GP  P G  G  G  G               PPGPPG+    G  G  GP G     G
Sbjct: 1086 PAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPG 1145

Query: 54   SAGGPSQPPGGGGPG 68
            SAG P +    G PG
Sbjct: 1146 SAGAPGKDGLNGLPG 1160



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 25/62 (40%), Positives = 25/62 (40%), Gaps = 4/62 (6%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGGGSAGGPSQPPGG 64
           G   P      G  G  G  G   P GP G   R G  G PG  GP G    GP  PPG 
Sbjct: 98  GSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPP--GPPGPPGL 155

Query: 65  GG 66
           GG
Sbjct: 156 GG 157



 Score = 34.7 bits (78), Expect = 0.31
 Identities = 29/73 (39%), Positives = 29/73 (39%), Gaps = 14/73 (19%)

Query: 10  PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGG------------GPGGGSAG 56
           P GP  PAG  G  G  G    PGPPG  G  G  G GG               GG S  
Sbjct: 119 PRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVP 178

Query: 57  GPSQPPGGGG-PG 68
           GP  P G  G PG
Sbjct: 179 GPMGPSGPRGLPG 191



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 25/64 (39%), Positives = 26/64 (40%), Gaps = 6/64 (9%)

Query: 10   PPGPPPPAGGGGGAGGAGGGP-PPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPG 68
            P GPP P G  G AG   G P PPGPPG      G P  G         P +    GG  
Sbjct: 1161 PIGPPGPRGRTGDAGPV-GPPGPPGPPGP----PGPPSAGFDFSFLPQPPQEKAHDGGRY 1215

Query: 69   IRKD 72
             R D
Sbjct: 1216 YRAD 1219


>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
          Length = 365

 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 85/354 (24%), Positives = 145/354 (40%), Gaps = 37/354 (10%)

Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
           VG IIG+ GE + K++++SG ++ IS   G  PER ++L G   ++ KA  M+ D +   
Sbjct: 25  VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
                    ++    +      +++PA + G +IGKGG  IK+++E  G ++ +  D   
Sbjct: 83  ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139

Query: 276 NTNVDKPLRIIGDPYK----VQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-P 330
           N + ++ + I G P      V+Q C ++++ L +                  G+ +P  P
Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLETLSQSPP--------------KGVTIPYRP 184

Query: 331 RHSVGVVIGRSGEMIKKIQNDAG-----VRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
           + S   VI   G+      +D+              D  GP   A+ +            
Sbjct: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 244

Query: 386 INDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFS----IPTHKCGLVIG 441
               L   +S  P   G  G           +G WG      T S    IP    G +IG
Sbjct: 245 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIG 304

Query: 442 RGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
           R G  +  I Q +GA ++I+  +  + D   +   I GS   I  A+ LI  ++
Sbjct: 305 RQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 355



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 62/230 (26%), Positives = 93/230 (40%), Gaps = 37/230 (16%)

Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
           VG +IG+ GE +KK++ ++G RI   +  G  PE+I  + GP +    A  +I D L+  
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            S           PP                  +   +P  +CG +IG+GG  +K I + 
Sbjct: 83  ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126

Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIE--------GPLCPVGP 504
           TGA V+++  + PN     +   I G PQ  I+  KQ+    +E        G   P  P
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRP 184

Query: 505 GPGGPGP--AGPMGPFNPGPFNQGPPGAP------PHAGGPPPHQYPPQG 546
            P       AG    ++ G  +   P         P   GPP   Y  QG
Sbjct: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQG 234



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 17/197 (8%)

Query: 229 GGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIG 287
           GG N T+   ++  GK  G +IGK GE++K+++E +G ++ +    S+    ++ + + G
Sbjct: 8   GGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAG 63

Query: 288 DPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKK 347
               + +A  M++D L E D       +   SR    + + VP    G +IG+ G  IK+
Sbjct: 64  PTNAIFKAFAMIIDKL-EEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKE 122

Query: 348 IQNDAGVRIQFKQDD-GTGPEKIAHIMG-PPDRCEHAARIINDLLQSLRSGP-------- 397
           I+   G ++Q   D      E+   I G P    E   +I   +L++L   P        
Sbjct: 123 IRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPY 182

Query: 398 -PGPPGGPGMPPGGRGR 413
            P P   P +  GG+ R
Sbjct: 183 RPKPSSSPVIFAGGQDR 199



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 25/73 (34%), Positives = 47/73 (64%)

Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205
           + E  +P+ ++G IIGR G +IN+I+Q SG +++I+    G  +R V++TG+  S+  A+
Sbjct: 289 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 348

Query: 206 MMLDDIVSRGRGG 218
            +++  +S   GG
Sbjct: 349 YLINVRLSSETGG 361



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%)

Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
           + ISS +       R  +T    VP    G +IG+GG +I +I++ +G +VQ++ D   L
Sbjct: 81  EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138

Query: 188 P---ERSVSLTGAPESV 201
           P   ER++++ G P+S+
Sbjct: 139 PNSTERAITIAGIPQSI 155



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 18/71 (25%), Positives = 31/71 (43%)

Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
           ++ +P   +G +IGR G  I +I+  +G +I+         ++   I G       A  +
Sbjct: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 350

Query: 386 INDLLQSLRSG 396
           IN  L S   G
Sbjct: 351 INVRLSSETGG 361


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 72/226 (31%), Positives = 84/226 (37%), Gaps = 35/226 (15%)

Query: 501 PVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPH 560
           P+GPGPG  GP  P+ P  P    Q PP   P    PPPHQ PP    +   Q  PP P 
Sbjct: 46  PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQ-PPPPPQ 104

Query: 561 DPSKAAAA----------AADPNAAWAAYYSHYYQ-QPPGPVPGPAPAPAAPPAQGEPPQ 609
           D SK   A          +A P ++ A   +      PPG  PGP P P        P  
Sbjct: 105 DSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGA 164

Query: 610 PPPTGQSDYTKAWEEYYKKIGQQPQQ------PGAPPQQDYTKAWEEYYKKQAQVATGGG 663
           PPPT  S           + G  P        PG  P+Q       +  K       GGG
Sbjct: 165 PPPTPPSSGVPTTP---PQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGG 221

Query: 664 PG--------APP---GSQPDYSAAWAEYYRQQAAYYGQTPGPGGP 698
           PG         PP   G +P         Y QQ   + Q P PGGP
Sbjct: 222 PGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQ---HHQGPPPGGP 264



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 32/69 (46%), Positives = 35/69 (50%), Gaps = 7/69 (10%)

Query: 6   TGGPPPGPPP--PAGGGGGAGGAGGGPPPGP---PGAGDRGGGGPGGGGPGGGSAGGPSQ 60
           T  PP  PPP  P+ G        GGPPP P   PG G     GPG GGP GG   G  +
Sbjct: 158 TSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPK 217

Query: 61  PPGGGGPGI 69
           P  GGGPG+
Sbjct: 218 P--GGGPGL 224



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 31/63 (49%), Positives = 33/63 (52%), Gaps = 5/63 (7%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPP--GG 64
           GGPPP   PPA   G   G   GP PG P  G   GG   GGGPG  + GG  +PP  GG
Sbjct: 182 GGPPP---PPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGG 238

Query: 65  GGP 67
           G P
Sbjct: 239 GEP 241



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 32/77 (41%), Positives = 33/77 (42%), Gaps = 12/77 (15%)

Query: 8   GPPPGPPPPAGGGGGAGGA--GGGPPPGPPGAGDRGGGGP----GGGGPGGGSAGGP--- 58
           GP PGP    G GG  GG   GG  P G PG    GG       GGG P GG    P   
Sbjct: 193 GPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYH 252

Query: 59  ---SQPPGGGGPGIRKD 72
               Q P  GGPG R +
Sbjct: 253 QQHHQGPPPGGPGGRSE 269



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 25/63 (39%), Positives = 29/63 (46%), Gaps = 6/63 (9%)

Query: 5   STGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGG 64
           S+  PP  PP      G   G+G GP P PP A       PG   P   S+G P+ PP  
Sbjct: 128 SSSAPPATPPT----SGAPPGSGPGPTPTPPPAVT--SAPPGAPPPTPPSSGVPTTPPQA 181

Query: 65  GGP 67
           GGP
Sbjct: 182 GGP 184



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 26/61 (42%), Positives = 27/61 (44%), Gaps = 14/61 (22%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGG-------------GPGGGGPGGG 53
           GG  PG P P GGG G    GG P P   G G+  GG             GP  GGPGG 
Sbjct: 209 GGKMPGGPKP-GGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGR 267

Query: 54  S 54
           S
Sbjct: 268 S 268



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 26/64 (40%), Positives = 26/64 (40%), Gaps = 14/64 (21%)

Query: 497 GPLCPVGPGPGGPG----PAGPMGPFNPGPFNQGPPGAPPHAGG----------PPPHQY 542
           GP    GPGPGGP     P GP     PG    G    PPH GG          PP HQ 
Sbjct: 195 GPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQ 254

Query: 543 PPQG 546
             QG
Sbjct: 255 HHQG 258



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 21/45 (46%), Positives = 21/45 (46%), Gaps = 1/45 (2%)

Query: 18 GGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPP 62
          GGGGG GG      P PPG G     GP G GPG      P  PP
Sbjct: 20 GGGGGRGGLHDFRSP-PPGMGLNQNRGPMGPGPGQSGPKPPIPPP 63



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 26/61 (42%), Positives = 26/61 (42%), Gaps = 13/61 (21%)

Query: 15  PPAGGGGGAG-GAGGGPPPGPPGAGDRGGG------GPGGGGPGGGSAGGPSQPPGGGGP 67
           PP GGGGG G  A  G PP        G        G GG GP GG      Q P G GP
Sbjct: 632 PPLGGGGGIGYEANPGVPPATMSGSMMGSDMRTERFGQGGAGPVGG------QGPRGMGP 685

Query: 68  G 68
           G
Sbjct: 686 G 686



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 24/61 (39%), Positives = 25/61 (40%), Gaps = 11/61 (18%)

Query: 9   PPPGP-----PPPAGGGGGAGGAGGGPPPGP--PGAGDRGGGGPGGGGPGGGSAGGPSQP 61
           PPP P     P  A G G A G G  PP     P A     G P G GPG      P+ P
Sbjct: 99  PPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPT----PTPP 154

Query: 62  P 62
           P
Sbjct: 155 P 155



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 28/92 (30%), Positives = 33/92 (35%), Gaps = 27/92 (29%)

Query: 396 GPPGPPG-------------GPGMPPGGRGRGRGQGNWGP----PGGEMTFSIPTHKCGL 438
           GPP PP              GPG P GG+  G  +   GP    PGG      P H    
Sbjct: 183 GPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPK---PPH---- 235

Query: 439 VIGRGGENVKAINQQTGAFVEISRQLPPNGDP 470
              RGG   +   Q    + +   Q PP G P
Sbjct: 236 ---RGGGEPRGGRQHHPPYHQQHHQGPPPGGP 264



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 35/127 (27%), Positives = 54/127 (42%), Gaps = 23/127 (18%)

Query: 297 EMVMDILRERDQG----GFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDA 352
           EM   + R+R++     G+ D  E   R+GGG  +     ++G   G  G+    +    
Sbjct: 584 EMEEQMRRQREESYSRMGYMDPRERDMRMGGGGAM-----NMGDPYGSGGQKFPPLGGGG 638

Query: 353 GVRIQFKQDDGTGPEKIA-HIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPG-- 409
           G  I ++ + G  P  ++  +MG   R E   +          +GP G  G  GM PG  
Sbjct: 639 G--IGYEANPGVPPATMSGSMMGSDMRTERFGQG--------GAGPVGGQGPRGMGPGTP 688

Query: 410 -GRGRGR 415
            G GRGR
Sbjct: 689 AGYGRGR 695



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 9/67 (13%)

Query: 41  GGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNST 100
           GGG    G P G  +GG   PP GGG GI  +A    V  A    + +G D        T
Sbjct: 614 GGGAMNMGDPYG--SGGQKFPPLGGGGGIGYEA-NPGVPPATMSGSMMGSDM------RT 664

Query: 101 PDFGFGG 107
             FG GG
Sbjct: 665 ERFGQGG 671


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 189/758 (24%), Positives = 234/758 (30%), Gaps = 150/758 (19%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQP--PGG-- 64
            PPGP    G  G  G  G    PGP GA G+RG  G  G     G  G P +P  PG   
Sbjct: 514  PPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARG 573

Query: 65   --GGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQP---- 118
              G PG++          A     + G   +  +       G  G K    D  +P    
Sbjct: 574  LTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAG 633

Query: 119  ----ESKKLASQGDSISSQLGPIHPPPRTSMTEEYRV--PDGMVGL-----IIGRGGEQI 167
                  ++ A   D      GP+ PP       E     P G  GL       G GG+  
Sbjct: 634  NAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPG 693

Query: 168  NK-IQQDSGCKVQISP--DSGGLPER-SVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQF 223
            ++ +  D G    + P  + G   ER    +TG P     A     D   +G  GP G  
Sbjct: 694  DQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPD-GPKGSPGPSGTP 752

Query: 224  HDNANGGQNGTVQEIMI-----PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTN 278
             D    G  G   E  I     P G  G +  KG E         G+   L   G     
Sbjct: 753  GDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPT 812

Query: 279  VDK----PLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSV 334
             +K    P  ++G P                  +G  G R E G     G   P      
Sbjct: 813  GEKGEPGPRGLVGPP----------------GSRGNPGSRGENGPTGAVGFAGPQGPDGQ 856

Query: 335  GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394
              V G  GE  +K   DAG           GP+ +A   GP     H    +  L     
Sbjct: 857  PGVKGEPGEPGQK--GDAG---------SPGPQGLAGSPGP-----HGPNGVPGLKGG-- 898

Query: 395  SGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQT 454
             G  GPPG  G  PG  GR    G  G PG       P          G E    +    
Sbjct: 899  RGTQGPPGATGF-PGSAGRVGPPGPAGAPGPAGPLGEP----------GKEGPPGLRGDP 947

Query: 455  GAFVEISRQLP--PNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG------- 505
            G+   +  + P  P G P  K     G P          E+   GP  P GP        
Sbjct: 948  GSHGRVGDRGPAGPPGGPGDK-----GDPG---------EDGQPGPDGPPGPAGTTGQRG 993

Query: 506  -------------PGGPGPAGPMGPFNP--GPFNQGPPG--APPHAGGPPPHQYPPQGWG 548
                         PG PGPAG  G   P     ++GPPG   PP + GP     P    G
Sbjct: 994  IVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAG 1053

Query: 549  NTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPP 608
            N       P             DP  A         Q  PG  PGP  AP     +G+P 
Sbjct: 1054 ND----GTPGRDGAVGERGDRGDPGPAGLP----GSQGAPG-TPGPVGAPGDAGQRGDPG 1104

Query: 609  QPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPP 668
               P G            K+    PQ P         +        +      G PG PP
Sbjct: 1105 SRGPIGPPGRAG------KRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPG-PP 1157

Query: 669  GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQG 706
            G   +  +A               PGP GP+ PP   G
Sbjct: 1158 GPNGEQGSA-------------GIPGPFGPRGPPGPVG 1182



 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 178/733 (24%), Positives = 227/733 (30%), Gaps = 214/733 (29%)

Query: 11  PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGG-PGGGGPGG--GSAGGPSQPPGGGG 66
           PG  P   G  G  G  G  PPG  G  G+RG  G PG  GP G  G  G P QP   G 
Sbjct: 118 PGLVPVVTGIRGRPGPAG--PPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGP 175

Query: 67  PGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQ 126
           PG       D + R                        F  Q   L+     E   L SQ
Sbjct: 176 PGHPSHPGPDGLSRP-----------------------FSAQMAGLD-----EKSGLGSQ 207

Query: 127 GDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGG 186
              +   +GP+ P          R P G+ G              Q  G      P   G
Sbjct: 208 VGLMPGSVGPVGP----------RGPQGLQG--------------QQGGAGPTGPPGEPG 243

Query: 187 LPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAG 246
            P                   +  I SRG  GPPG+  ++   G+NG   E+   AG  G
Sbjct: 244 DPGP-----------------MGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGF-AGSPG 285

Query: 247 LVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEM----VMDI 302
                G   +  L+   G K            ++ P   +G P    +A        M  
Sbjct: 286 ARGFPGAPGLPGLKGHRGHK-----------GLEGPKGEVGAPGSKGEAGPTGPMGAMGP 334

Query: 303 LRER----DQGGFGDRNEYGSRIGGGID-VPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQ 357
           L  R    ++G  G +   G R   G+   P P   +G+  G SG        + G++ +
Sbjct: 335 LGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIP-GSSG-----FPGNPGMKGE 388

Query: 358 FKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--------PG 409
                  GPE      GP               Q   +GPPGP G PG+P        PG
Sbjct: 389 AGPTGARGPE------GPQG-------------QRGETGPPGPVGSPGLPGAIGTDGTPG 429

Query: 410 GRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTG--AFVEISRQLPPN 467
            +G     G  GPPG       P  +       G    + I  Q G         +  P 
Sbjct: 430 AKGPTGSPGTSGPPGSAGPPGSPGPQ-------GSTGPQGIRGQPGDPGVPGFKGEAGPK 482

Query: 468 GDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP----GP-GGPGPAGPMGPFNP-- 520
           G+P                        I+GP+ P G     GP G PG  GP GP     
Sbjct: 483 GEPG--------------------PHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERG 522

Query: 521 GPFNQGPPGAP--PHAGGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAA 578
            P N+G PG+   P   G    + P    G    Q  P  P +P    A     N     
Sbjct: 523 APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPG--- 579

Query: 579 YYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGA 638
                 Q P G + GP  AP      GE  +P P G              I  QP   G 
Sbjct: 580 -----VQGPEGKL-GPLGAP------GEDGRPGPPGSIG-----------IRGQPGSMGL 616

Query: 639 PPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGP 698
           P  +                    G    PG   +   A     R      G+  GP GP
Sbjct: 617 PGPK--------------------GSSGDPGKPGEAGNAGVPGQRGAPGKDGEV-GPSGP 655

Query: 699 QPPPTQQGQQQAQ 711
             PP   G++  Q
Sbjct: 656 VGPPGLAGERGEQ 668



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 176/648 (27%), Positives = 221/648 (34%), Gaps = 144/648 (22%)

Query: 6   TGGPP--PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPP 62
           T GPP   GPP   G  G  G  G    PG PG  G +G  GP G  PG     GP  PP
Sbjct: 439 TSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGE-PGPHGIQGPIGPP 497

Query: 63  GGGGP-GIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGF-------GGQKRQLED 114
           G  G  G R D               +G         +  + GF       G +  Q E 
Sbjct: 498 GEEGKRGPRGD------------PGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGER 545

Query: 115 GDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRV--PDGMVGLIIGRGGEQINKIQQ 172
           G    S    SQGD    + G    P    +T    V  P+G +G  +G  GE   +   
Sbjct: 546 GPVGSSGPKGSQGD--PGRPGEPGLPGARGLTGNPGVQGPEGKLG-PLGAPGED-GRPGP 601

Query: 173 DSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQN 232
                ++  P S GLP    S +G P    +A          G  G PGQ       G+ 
Sbjct: 602 PGSIGIRGQPGSMGLPGPKGS-SGDPGKPGEA----------GNAGVPGQRGAPGKDGEV 650

Query: 233 GTVQEIMIP--AGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPY 290
           G    +  P  AG+ G     G    + L    G      + G Q         + GDP 
Sbjct: 651 GPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQG--------VPGDP- 701

Query: 291 KVQQACEMVMDILRERDQGGFGDRNEYG-------SRIGGGIDVPVPRHSVGVVIGRSGE 343
                   V  +    ++G  G+R E G         + GG     P+ S G   G  G+
Sbjct: 702 ------GAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPG-PSGTPGD 754

Query: 344 M----IKKIQNDAGVRIQFKQDDGT-GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPP 398
                ++ +  + G+        GT GP+     +G       A    ND  + L  GP 
Sbjct: 755 TGPPGLQGMPGERGIA-------GTPGPKGDRGGIGEKGAEGTAG---NDGARGL-PGPL 803

Query: 399 GPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFV 458
           GPP GP  P G +G    +G  GPPG                 RG    +  N  TGA V
Sbjct: 804 GPP-GPAGPTGEKGEPGPRGLVGPPG----------------SRGNPGSRGENGPTGA-V 845

Query: 459 EISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG-PGP----GGPGPAG 513
             +    P+G P      ++G P +             G     G PGP    G PGP G
Sbjct: 846 GFAGPQGPDGQPG-----VKGEPGE------------PGQKGDAGSPGPQGLAGSPGPHG 888

Query: 514 PMG--PFNPGPFNQGPPGA---PPHAG--GPPPHQYPPQGWGNTYPQWQPPAPHDPSKAA 566
           P G      G   QGPPGA   P  AG  GPP    P    G   P  +P     P    
Sbjct: 889 PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG---PAGAPGPAGPLGEPGKEGPP---- 941

Query: 567 AAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTG 614
               DP        SH      GP  GP   P      GE  QP P G
Sbjct: 942 GLRGDPG-------SHGRVGDRGPA-GPPGGPGDKGDPGEDGQPGPDG 981



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 174/663 (26%), Positives = 215/663 (32%), Gaps = 130/663 (19%)

Query: 10   PPGPPPPAGGGGGAGGAG-----GGP-PPGPPGAGDRGGGGPGGGG-PGGGSAGGPSQPP 62
            P GPP  AG  G  G  G     G P PPGPPG G    G PG  G PG   A GP  P 
Sbjct: 655  PVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEG----GKPGDQGVPGDPGAVGPLGPR 710

Query: 63   GG-GGPGIRKDAFADAVQRARQIAAKIG--------GDAATTVNNSTPDF-GFGGQKRQL 112
            G  G PG R +     +   + +A   G        G + T  +   P   G  G++   
Sbjct: 711  GERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIA 770

Query: 113  ----EDGDQPESKKLASQG----DSISSQLGPIHPPPRTSMTEEYRVPD--GMVGLIIGR 162
                  GD+    +  ++G    D      GP+ PP     T E   P   G+VG    R
Sbjct: 771  GTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSR 830

Query: 163  GGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAP-ESVQKAKMMLDDIVSRGRGGPPG 221
            G          +G      P     P+    + G P E  QK          +G  G PG
Sbjct: 831  GNPGSRGENGPTGAVGFAGPQG---PDGQPGVKGEPGEPGQKGDAGSPG--PQGLAGSPG 885

Query: 222  QFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDK 281
                N   G  G  +    P G  G     G           G    L + G +      
Sbjct: 886  PHGPNGVPGLKGG-RGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEG----- 939

Query: 282  PLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSVGV--VI 338
            P  + GDP    +    V D       GG GD+ + G     G D P  P  + G   ++
Sbjct: 940  PPGLRGDPGSHGR----VGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIV 995

Query: 339  GRSGEMIKK----IQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394
            G  G+  ++    +   AG   +      TG +     +GPP                  
Sbjct: 996  GMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGE---------- 1045

Query: 395  SGPPGPPGGPGMP--------------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVI 440
             GP GP G  G P              PG  G    QG  G PG       P    G   
Sbjct: 1046 PGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPG-------PVGAPGDAG 1098

Query: 441  GRGGENVKAINQQTGAFVEISRQLP----PNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE 496
             RG    +      G   +  R LP    P GD        RG   Q  H      + + 
Sbjct: 1099 QRGDPGSRGPIGPPGRAGK--RGLPGPQGPRGDKGDHGD--RGDRGQKGHRGFTGLQGLP 1154

Query: 497  GPLCPVGPG-----PGGPGPAGPMGPF-------NPGPFNQ-GPPGAPPHAG-----GPP 538
            GP  P G       PG  GP GP GP        NPGP    GPPG     G     GPP
Sbjct: 1155 GPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPP 1214

Query: 539  PHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAP 598
                PP           PP P  P    AA  D          HY +  P P+P      
Sbjct: 1215 GEPGPP----------GPPGP--PGHLTAALGD-------IMGHYDESMPDPLPEFTEDQ 1255

Query: 599  AAP 601
            AAP
Sbjct: 1256 AAP 1258



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 155/624 (24%), Positives = 204/624 (32%), Gaps = 114/624 (18%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPG----GGSAGGPSQPP 62
           G  P GPP   G  G  G  G   P GPPG     G     G PG     GS G    P 
Sbjct: 232 GAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPG 291

Query: 63  GGGGPGIRKDAFADAVQRARQIAAKIG--GDAATT----VNNSTPDFGFGGQKRQLEDGD 116
             G PG++       ++  +      G  G+A  T            G  G++ +L  G 
Sbjct: 292 APGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRL--GP 349

Query: 117 QPESKKLASQGDSISSQLGPIHP--PPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDS 174
           Q    +  + G  +  + GP+ P   P +S         G  G    RG E     + ++
Sbjct: 350 QGAPGQRGAHG--MPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGET 407

Query: 175 GCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGT 234
           G    +   S GLP  ++   G P +            S G  GPPG      + G  G+
Sbjct: 408 GPPGPVG--SPGLP-GAIGTDGTPGAKGPTG-------SPGTSGPPGSAGPPGSPGPQGS 457

Query: 235 V--QEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKV 292
              Q I    G  G+   KG    K      G++  +   G +     +     GDP  V
Sbjct: 458 TGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPR-----GDPGTV 512

Query: 293 QQACEMVMDILRERDQGGFGDRNEYGSRIGGGID-VPVPRHSVGV--VIGRSGEMIKKIQ 349
                           G  G+R   G+R   G D +P P+ + G    +G SG   K  Q
Sbjct: 513 -------------GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGP--KGSQ 557

Query: 350 NDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPG 409
            D G   +       G      + GP  +                 G PG  G PG PPG
Sbjct: 558 GDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPL-------------GAPGEDGRPG-PPG 603

Query: 410 GRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGD 469
             G     G+ G PG + +   P        G+ GE   A                  G 
Sbjct: 604 SIGIRGQPGSMGLPGPKGSSGDP--------GKPGEAGNA------------------GV 637

Query: 470 PNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFN--QGP 527
           P       RG+P +             GP  PVGP PG  G  G  GP  P  F    GP
Sbjct: 638 PG-----QRGAPGKDGEV---------GPSGPVGP-PGLAGERGEQGPPGPTGFQGLPGP 682

Query: 528 PGAPPHAGGPPPHQYP--PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQ 585
           PG P   G P     P  P   G   P+ +   P +  +            A    H   
Sbjct: 683 PGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAG--GHGPD 740

Query: 586 QPPG-PVPGPAPAPAAPPA-QGEP 607
            P G P P   P    PP  QG P
Sbjct: 741 GPKGSPGPSGTPGDTGPPGLQGMP 764



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 47/142 (33%), Positives = 55/142 (38%), Gaps = 9/142 (6%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGGGGPGG--GGPG-GGSAG--GPSQP 61
            PGPP P G  G AG  G   P GPPG    +G  G  GP G  G PG  GS G  GP  P
Sbjct: 1154 PGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGP 1213

Query: 62   PGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESK 121
            PG  GP                I           +   T D      K + + G     K
Sbjct: 1214 PGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLK 1273

Query: 122  KLASQGDSISSQLGPIHPPPRT 143
             L+SQ +++ S  G    P RT
Sbjct: 1274 SLSSQIETMRSPDGSKKHPART 1295



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 113/430 (26%), Positives = 142/430 (33%), Gaps = 99/430 (23%)

Query: 7    GGPPP----GPPPPAGGGGGAGGAGGGPPPGPPGA----GDRGGGGPGGGGPGGGSAGGP 58
            G P P    G P P G  G  G  GG    GPPGA    G  G  GP G     G AG  
Sbjct: 873  GSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPL 932

Query: 59   SQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQP 118
             +P   G PG+R D  +      R  A   GG           D G  G     EDG   
Sbjct: 933  GEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPG---------DKGDPG-----EDG--- 975

Query: 119  ESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKV 178
                          Q GP  PP     T +     G+VG+   RG   +  +   +G   
Sbjct: 976  --------------QPGPDGPPGPAGTTGQ----RGIVGMPGQRGERGMPGLPGPAGTPG 1017

Query: 179  QISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEI 238
            ++ P      +      G P S              G  GP G   ++   G++G V   
Sbjct: 1018 KVGPTGATGDKGPPGPVGPPGSNGPV----------GEPGPEGPAGNDGTPGRDGAV--- 1064

Query: 239  MIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLR-IIGDPYKVQQACE 297
                G+ G     G   +   Q   G    +   G      D   R  IG P +  +   
Sbjct: 1065 ----GERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGL 1120

Query: 298  MVMDILR--ERDQGGFGDRNEYGSRIGGGID-VPVPRHSVGVVIGRSGEMIKKIQNDAGV 354
                  R  + D G  GDR + G R   G+  +P P        G +GE     Q  AG+
Sbjct: 1121 PGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP-------GPNGE-----QGSAGI 1168

Query: 355  RIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRG 414
               F      GP      +GP                S + G PGP G  G PPG RG  
Sbjct: 1169 PGPFGPRGPPGP------VGP----------------SGKEGNPGPLGPIG-PPGVRGSV 1205

Query: 415  RGQGNWGPPG 424
               G  GPPG
Sbjct: 1206 GEAGPEGPPG 1215



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 30/72 (41%), Positives = 33/72 (45%), Gaps = 5/72 (6%)

Query: 2   SDYSTGGPPP-GPPPPAGGGGGAGGAGGGPPPGPPGA----GDRGGGGPGGGGPGGGSAG 56
           +D + G P P GPP PAG  G  G  G     GPPG+    G RG  GP G     G  G
Sbjct: 793 NDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQG 852

Query: 57  GPSQPPGGGGPG 68
              QP   G PG
Sbjct: 853 PDGQPGVKGEPG 864



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 29/69 (42%), Positives = 30/69 (43%), Gaps = 3/69 (4%)

Query: 3    DYSTGGP--PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPS 59
            D    GP  PPG   P G  G  G AG    PG  GA G+RG  G  G     GS G P 
Sbjct: 1027 DKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPG 1086

Query: 60   QPPGGGGPG 68
             P   G PG
Sbjct: 1087 TPGPVGAPG 1095



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 32/90 (35%), Positives = 35/90 (38%), Gaps = 23/90 (25%)

Query: 1    MSDYSTGGPPPGP-----------PPPAGGGGGAGGAGGGPPPGPPG-AGDRG------- 41
            + D    GPP GP           P P G  G AG  G     G PG  G+RG       
Sbjct: 953  VGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGP 1012

Query: 42   GGGPGGGGPGGGSAG----GPSQPPGGGGP 67
             G PG  GP G +      GP  PPG  GP
Sbjct: 1013 AGTPGKVGPTGATGDKGPPGPVGPPGSNGP 1042



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 36/103 (34%), Positives = 36/103 (34%), Gaps = 40/103 (38%)

Query: 5    STGGP-PPGPPPPAGGGGGAGGAGGGPPPGPPGA-------------------GDRGGGG 44
            S G P  PGP    G  G  G  G   P GPPG                    GDRG  G
Sbjct: 1081 SQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG 1140

Query: 45   -------------PGGGGPGG--GSAG-----GPSQPPGGGGP 67
                         PG  GP G  GSAG     GP  PPG  GP
Sbjct: 1141 QKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGP 1183



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 55/187 (29%), Positives = 60/187 (32%), Gaps = 54/187 (28%)

Query: 455 GAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG-PGGPGPAG 513
           G    +  Q P  G+ NF     RG   Q          K E  L PV  G  G PGPAG
Sbjct: 90  GECCPVCSQTPGGGNTNFG----RGRKGQ----------KGEPGLVPVVTGIRGRPGPAG 135

Query: 514 PMGPFNP----GPFNQ----------GPPGAP--PHAGGPPPHQYPPQGWGNTYPQWQPP 557
           P G   P    GP  +          G PG P  P A GPP H   P           P 
Sbjct: 136 PPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHP----------GPD 185

Query: 558 APHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAP----------APAAPPAQGEP 607
               P  A  A  D  +   +          GPV    P           P  PP  GEP
Sbjct: 186 GLSRPFSAQMAGLDEKSGLGSQVG-LMPGSVGPVGPRGPQGLQGQQGGAGPTGPP--GEP 242

Query: 608 PQPPPTG 614
             P P G
Sbjct: 243 GDPGPMG 249


>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
          Length = 361

 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 82/350 (23%), Positives = 142/350 (40%), Gaps = 33/350 (9%)

Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
           VG IIG+ GE + K++++SG ++ IS   G  PER ++L G   ++ KA  M+ D +   
Sbjct: 25  VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
                    ++    +      +++PA + G +IGKGG  IK+++E  G ++ +  D   
Sbjct: 83  ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139

Query: 276 NTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSV 334
           N + ++ + I G P  + +  + +  ++ E                  G+ +P  P+ S 
Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLESPP--------------KGVTIPYRPKPSS 184

Query: 335 GVVIGRSGEMIKKIQNDAG-----VRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDL 389
             VI   G+      +D+              D  GP   A+ +                
Sbjct: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQ 244

Query: 390 LQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFS----IPTHKCGLVIGRGGE 445
           L   +S  P   G  G           +G WG      T S    IP    G +IGR G 
Sbjct: 245 LAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGA 304

Query: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
            +  I Q +GA ++I+  +  + D   +   I GS   I  A+ LI  ++
Sbjct: 305 KINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 351



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 62/226 (27%), Positives = 94/226 (41%), Gaps = 33/226 (14%)

Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
           VG +IG+ GE +KK++ ++G RI   +  G  PE+I  + GP +    A  +I D L+  
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            S           PP                  +   +P  +CG +IG+GG  +K I + 
Sbjct: 83  ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126

Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQ----LIEEKIEGPLCPVGPGPGG 508
           TGA V+++  + PN     +   I G PQ  I+  KQ    ++E   +G   P  P P  
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184

Query: 509 PGP--AGPMGPFNPGPFNQGPPGAP------PHAGGPPPHQYPPQG 546
                AG    ++ G  +   P         P   GPP   Y  QG
Sbjct: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQG 230



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 52/193 (26%), Positives = 89/193 (46%), Gaps = 13/193 (6%)

Query: 229 GGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIG 287
           GG N T+   ++  GK  G +IGK GE++K+++E +G ++ +    S+    ++ + + G
Sbjct: 8   GGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAG 63

Query: 288 DPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKK 347
               + +A  M++D L E D       +   SR    + + VP    G +IG+ G  IK+
Sbjct: 64  PTNAIFKAFAMIIDKL-EEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKE 122

Query: 348 IQNDAGVRIQFKQDD-GTGPEKIAHIMG-PPDRCEHAARIINDLLQSLRSG-----PPGP 400
           I+   G ++Q   D      E+   I G P    E   +I   +L+S   G      P P
Sbjct: 123 IRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKP 182

Query: 401 PGGPGMPPGGRGR 413
              P +  GG+ R
Sbjct: 183 SSSPVIFAGGQDR 195



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 25/73 (34%), Positives = 47/73 (64%)

Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205
           + E  +P+ ++G IIGR G +IN+I+Q SG +++I+    G  +R V++TG+  S+  A+
Sbjct: 285 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 344

Query: 206 MMLDDIVSRGRGG 218
            +++  +S   GG
Sbjct: 345 YLINVRLSSETGG 357



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%)

Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
           + ISS +       R  +T    VP    G +IG+GG +I +I++ +G +VQ++ D   L
Sbjct: 81  EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138

Query: 188 P---ERSVSLTGAPESV 201
           P   ER++++ G P+S+
Sbjct: 139 PNSTERAITIAGIPQSI 155



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 18/71 (25%), Positives = 31/71 (43%)

Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
           ++ +P   +G +IGR G  I +I+  +G +I+         ++   I G       A  +
Sbjct: 287 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 346

Query: 386 INDLLQSLRSG 396
           IN  L S   G
Sbjct: 347 INVRLSSETGG 357


>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
          Length = 366

 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 87/357 (24%), Positives = 150/357 (42%), Gaps = 42/357 (11%)

Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
           VG IIG+ GE + K++++SG ++ IS   G  PER ++L G   ++ KA  M+ D +   
Sbjct: 25  VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
                    ++    +      +++PA + G +IGKGG  IK+++E  G ++ +  D   
Sbjct: 83  ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139

Query: 276 NTNVDKPLRIIGDPYK----VQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-P 330
           N + ++ + I G P      V+Q C ++++ L +                  G+ +P  P
Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLETLSQSPP--------------KGVTIPYRP 184

Query: 331 RHSVGVVIGRSGEMIKKIQNDAG-----VRIQFKQDDGTGPEKIAH-IMG-----PPDRC 379
           + S   VI   G+      +D+              D  GP   A+ I G      PD  
Sbjct: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 244

Query: 380 EHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRG-QGNWGPPGGEMTFSIPTHKCGL 438
           +     +      +  G  G  G     P  +G   G   +      E+T  IP    G 
Sbjct: 245 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELT--IPNDLIGC 302

Query: 439 VIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
           +IGR G  +  I Q +GA ++I+  +  + D   +   I GS   I  A+ LI  ++
Sbjct: 303 IIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 356



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 62/230 (26%), Positives = 93/230 (40%), Gaps = 37/230 (16%)

Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
           VG +IG+ GE +KK++ ++G RI   +  G  PE+I  + GP +    A  +I D L+  
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            S           PP                  +   +P  +CG +IG+GG  +K I + 
Sbjct: 83  ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126

Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIE--------GPLCPVGP 504
           TGA V+++  + PN     +   I G PQ  I+  KQ+    +E        G   P  P
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRP 184

Query: 505 GPGGPGP--AGPMGPFNPGPFNQGPPGAP------PHAGGPPPHQYPPQG 546
            P       AG    ++ G  +   P         P   GPP   Y  QG
Sbjct: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQG 234



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 17/197 (8%)

Query: 229 GGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIG 287
           GG N T+   ++  GK  G +IGK GE++K+++E +G ++ +    S+    ++ + + G
Sbjct: 8   GGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAG 63

Query: 288 DPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKK 347
               + +A  M++D L E D       +   SR    + + VP    G +IG+ G  IK+
Sbjct: 64  PTNAIFKAFAMIIDKL-EEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKE 122

Query: 348 IQNDAGVRIQFKQDD-GTGPEKIAHIMG-PPDRCEHAARIINDLLQSLRSGP-------- 397
           I+   G ++Q   D      E+   I G P    E   +I   +L++L   P        
Sbjct: 123 IRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPY 182

Query: 398 -PGPPGGPGMPPGGRGR 413
            P P   P +  GG+ R
Sbjct: 183 RPKPSSSPVIFAGGQDR 199



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 25/73 (34%), Positives = 47/73 (64%)

Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205
           + E  +P+ ++G IIGR G +IN+I+Q SG +++I+    G  +R V++TG+  S+  A+
Sbjct: 290 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 349

Query: 206 MMLDDIVSRGRGG 218
            +++  +S   GG
Sbjct: 350 YLINVRLSSETGG 362



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%)

Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
           + ISS +       R  +T    VP    G +IG+GG +I +I++ +G +VQ++ D   L
Sbjct: 81  EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138

Query: 188 P---ERSVSLTGAPESV 201
           P   ER++++ G P+S+
Sbjct: 139 PNSTERAITIAGIPQSI 155



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 18/71 (25%), Positives = 31/71 (43%)

Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
           ++ +P   +G +IGR G  I +I+  +G +I+         ++   I G       A  +
Sbjct: 292 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 351

Query: 386 INDLLQSLRSG 396
           IN  L S   G
Sbjct: 352 INVRLSSETGG 362


>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
          Length = 345

 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 77/329 (23%), Positives = 136/329 (41%), Gaps = 81/329 (24%)

Query: 138 HPPPRTSMTEEYRVPDG---------------MVGLIIGRGGEQINKIQQDSGCKVQISP 182
           HP P+     E +V +G                VG IIG+ GE + K++++SG ++ IS 
Sbjct: 24  HPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINIS- 82

Query: 183 DSGGLPERSVSLTGAPESVQKAKMML-----DDIVSRGRGGPPGQFHDNANGGQNGTVQE 237
             G  PER V++TG  +++ KA  M+     +DI++     P           +      
Sbjct: 83  -EGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATS--------KPPVTLR 133

Query: 238 IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACE 297
           +++PA + G +IGKGG  IK+++E  G ++ +  D   N + ++ + I G P  + Q  +
Sbjct: 134 LVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN-STERAVTISGTPDAIIQCVK 192

Query: 298 MVMDILRE--RDQGGF-------------------------------GDR-----NEYGS 319
            +  ++ E    QG +                               G++     +E   
Sbjct: 193 QICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQ 252

Query: 320 RIGG---GID---------VPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPE 367
            + G   G+D         + +P   +G +IGR G  I +I+  +G +I+         E
Sbjct: 253 NLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSE 312

Query: 368 KIAHIMGPPDRCEHAARIINDLLQSLRSG 396
           +   I G P     A  +IN  L S  +G
Sbjct: 313 RQITITGTPANISLAQYLINARLTSEVTG 341



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 54/197 (27%), Positives = 87/197 (44%), Gaps = 39/197 (19%)

Query: 300 MDILRERDQGGFGDRNEYGSRIG-GGIDVPVPRH------SVGVVIGRSGEMIKKIQNDA 352
           +  L    Q  FG R E  S++  GG++V +          VG +IG+ GE +KK++ ++
Sbjct: 18  LSTLSHHPQPQFGRRME--SKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREES 75

Query: 353 GVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARII-----NDLLQSLRSGPPGPPGGPGMP 407
           G RI   +  G  PE+I  I GP D    A  +I      D++ S+ + P          
Sbjct: 76  GARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPAT-------- 125

Query: 408 PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPN 467
                          P   +   +P  +CG +IG+GG  +K I + TGA V+++  + PN
Sbjct: 126 -------------SKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN 172

Query: 468 GDPNFKLFIIRGSPQQI 484
                +   I G+P  I
Sbjct: 173 STE--RAVTISGTPDAI 187



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 75/314 (23%), Positives = 126/314 (40%), Gaps = 45/314 (14%)

Query: 227 ANGGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285
           + GG N T+   ++  GK  G +IGK GET+K+++E +G ++ +    S+    ++ + I
Sbjct: 38  SEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI----SEGNCPERIVTI 93

Query: 286 IGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMI 345
            G    + +A  M+     E D       +   S+    + + VP    G +IG+ G  I
Sbjct: 94  TGPTDAIFKAFAMIAYKFEE-DIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152

Query: 346 KKIQNDAGVRIQFKQDD-GTGPEKIAHIMGPPDRCEHAARII------------------ 386
           K+I+   G ++Q   D      E+   I G PD      + I                  
Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPH 212

Query: 387 ---NDLLQSLRSGPPGPPGGPGMP--PGGRG-----------RGRGQG-NWGPPGGEMTF 429
                L Q      P PP G   P  PG +             G+  G +  PP      
Sbjct: 213 PDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHEL 272

Query: 430 SIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQ 489
           +IP    G +IGR G  +  I Q +GA ++I+     + +   +   I G+P  I  A+ 
Sbjct: 273 TIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSE---RQITITGTPANISLAQY 329

Query: 490 LIEEKIEGPLCPVG 503
           LI  ++   +  +G
Sbjct: 330 LINARLTSEVTGMG 343



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 32/105 (30%), Positives = 60/105 (57%), Gaps = 10/105 (9%)

Query: 105 FGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGG 164
           F G+K  L   +  E++ L  Q   + +       PP +  T E  +P+ ++G IIGR G
Sbjct: 238 FPGEKLPLHSSE--EAQNLMGQSSGLDAS------PPAS--THELTIPNDLIGCIIGRQG 287

Query: 165 EQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLD 209
            +IN+I+Q SG +++I+  + G  ER +++TG P ++  A+ +++
Sbjct: 288 TKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 332


>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
          Length = 362

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 84/353 (23%), Positives = 147/353 (41%), Gaps = 38/353 (10%)

Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
           VG IIG+ GE + K++++SG ++ IS   G  PER ++L G   ++ KA  M+ D +   
Sbjct: 25  VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
                    ++    +      +++PA + G +IGKGG  IK+++E  G ++ +  D   
Sbjct: 83  ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139

Query: 276 NTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSV 334
           N + ++ + I G P  + +  + +  ++ E                  G+ +P  P+ S 
Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLESPP--------------KGVTIPYRPKPSS 184

Query: 335 GVVIGRSGEMIKKIQNDAG-----VRIQFKQDDGTGPEKIAH-IMG-----PPDRCEHAA 383
             VI   G+      +D+              D  GP   A+ I G      PD  +   
Sbjct: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQ 244

Query: 384 RIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRG-QGNWGPPGGEMTFSIPTHKCGLVIGR 442
             +      +  G  G  G     P  +G   G   +      E+T  IP    G +IGR
Sbjct: 245 LAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELT--IPNDLIGCIIGR 302

Query: 443 GGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
            G  +  I Q +GA ++I+  +  + D   +   I GS   I  A+ LI  ++
Sbjct: 303 QGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 352



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 62/226 (27%), Positives = 94/226 (41%), Gaps = 33/226 (14%)

Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
           VG +IG+ GE +KK++ ++G RI   +  G  PE+I  + GP +    A  +I D L+  
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            S           PP                  +   +P  +CG +IG+GG  +K I + 
Sbjct: 83  ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126

Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQ----LIEEKIEGPLCPVGPGPGG 508
           TGA V+++  + PN     +   I G PQ  I+  KQ    ++E   +G   P  P P  
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184

Query: 509 PGP--AGPMGPFNPGPFNQGPPGAP------PHAGGPPPHQYPPQG 546
                AG    ++ G  +   P         P   GPP   Y  QG
Sbjct: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQG 230



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 52/193 (26%), Positives = 89/193 (46%), Gaps = 13/193 (6%)

Query: 229 GGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIG 287
           GG N T+   ++  GK  G +IGK GE++K+++E +G ++ +    S+    ++ + + G
Sbjct: 8   GGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAG 63

Query: 288 DPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKK 347
               + +A  M++D L E D       +   SR    + + VP    G +IG+ G  IK+
Sbjct: 64  PTNAIFKAFAMIIDKL-EEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKE 122

Query: 348 IQNDAGVRIQFKQDD-GTGPEKIAHIMG-PPDRCEHAARIINDLLQSLRSG-----PPGP 400
           I+   G ++Q   D      E+   I G P    E   +I   +L+S   G      P P
Sbjct: 123 IRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKP 182

Query: 401 PGGPGMPPGGRGR 413
              P +  GG+ R
Sbjct: 183 SSSPVIFAGGQDR 195



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 25/73 (34%), Positives = 47/73 (64%)

Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205
           + E  +P+ ++G IIGR G +IN+I+Q SG +++I+    G  +R V++TG+  S+  A+
Sbjct: 286 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 345

Query: 206 MMLDDIVSRGRGG 218
            +++  +S   GG
Sbjct: 346 YLINVRLSSETGG 358



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%)

Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
           + ISS +       R  +T    VP    G +IG+GG +I +I++ +G +VQ++ D   L
Sbjct: 81  EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138

Query: 188 P---ERSVSLTGAPESV 201
           P   ER++++ G P+S+
Sbjct: 139 PNSTERAITIAGIPQSI 155



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 18/71 (25%), Positives = 31/71 (43%)

Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
           ++ +P   +G +IGR G  I +I+  +G +I+         ++   I G       A  +
Sbjct: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 347

Query: 386 INDLLQSLRSG 396
           IN  L S   G
Sbjct: 348 INVRLSSETGG 358


>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
           isoform b [Homo sapiens]
          Length = 556

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 88/391 (22%), Positives = 154/391 (39%), Gaps = 75/391 (19%)

Query: 113 EDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYR------VPDGMVGLIIGRGGEQ 166
           E+   P   + A +GD  S + G  H P  TS   +        VP   VG IIG+ G  
Sbjct: 158 EEVSSPSPPQRAQRGDHSSREQG--HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLT 215

Query: 167 INKIQQDSGCKVQIS-PDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHD 225
           I  I + +  +V I   ++ G  E+ V++   PE   +A  M+ +I+ +          D
Sbjct: 216 IKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEA--------D 267

Query: 226 NANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285
                +   ++ I+   G  G +IGK G  +K+++   G K+ +     Q+ ++  P R 
Sbjct: 268 ETKLAEEIPLK-ILAHNGLVGRLIGKEGRNLKKIEHETGTKITI--SSLQDLSIYNPERT 324

Query: 286 IGDPYKVQQACEMVMDILR------ERDQGGFGDRNEYGSRIGGG--------------- 324
           I     V+      ++I++      E D       + Y S +                  
Sbjct: 325 ITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQ 384

Query: 325 --IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTG-PEKIAHIMGPPD-RCE 380
             +++ +P  +VG +IG+ G  IK++   AG  I+    +G    E++  I GPP+ + +
Sbjct: 385 EIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFK 444

Query: 381 HAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFS----IPTHKC 436
              RI   L +                           N+  P  E+       +P+   
Sbjct: 445 AQGRIFGKLKEE--------------------------NFFNPKEEVKLEAHIRVPSSTA 478

Query: 437 GLVIGRGGENVKAINQQTGAFVEISRQLPPN 467
           G VIG+GG+ V  +   T A V + R   P+
Sbjct: 479 GRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 509



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 52/181 (28%), Positives = 90/181 (49%), Gaps = 15/181 (8%)

Query: 133 QLGPI---HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSG-GLP 188
           Q GP    H  P   +   + +P   VG IIG+ G  I ++ + +G  ++I+P  G  + 
Sbjct: 371 QFGPFPHHHSYPEQEIVNLF-IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS 429

Query: 189 ERSVSLTGAPESVQKAK-MMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGL 247
           ER V +TG PE+  KA+  +   +       P  +    A+         I +P+  AG 
Sbjct: 430 ERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAH---------IRVPSSTAGR 480

Query: 248 VIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERD 307
           VIGKGG+T+ +LQ     ++I+ +D + + N +  +RIIG  +  Q A   + +I+++  
Sbjct: 481 VIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 540

Query: 308 Q 308
           Q
Sbjct: 541 Q 541



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 71/277 (25%), Positives = 123/277 (44%), Gaps = 36/277 (12%)

Query: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQIS---PDSGGLPERSVSLTGAPESVQKAKMML- 208
           +G+VG +IG+ G  + KI+ ++G K+ IS     S   PER++++ G  E+   A++ + 
Sbjct: 283 NGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIM 342

Query: 209 ---------DDIVSRGRGG------PPGQF----HDNANGGQNGTVQEIMIPAGKAGLVI 249
                    D +      G      P  QF    H ++   Q   +  + IP    G +I
Sbjct: 343 KKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQE--IVNLFIPTQAVGAII 400

Query: 250 GKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQ-QACEMVMDILRERDQ 308
           GK G  IKQL   AG  + +    ++  +V + + II  P + Q +A   +   L+E  +
Sbjct: 401 GKKGAHIKQLARFAGASIKIAP--AEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE--E 456

Query: 309 GGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQN--DAGVRIQFKQDDGTGP 366
             F  + E    +     + VP  + G VIG+ G+ + ++QN   A V +   Q      
Sbjct: 457 NFFNPKEE----VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENE 512

Query: 367 EKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGG 403
           E I  I+G     + A R I +++Q ++      P G
Sbjct: 513 EVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQG 549



 Score = 33.1 bits (74), Expect = 0.92
 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 13/102 (12%)

Query: 401 PGGPGMPPGGRGRGRGQGNWGPPGGE---------MTFSIPTHKCGLVIGRGGENVKAIN 451
           P  P     G    R QG+   PGG          +   +PT   G +IG+ G  +K I 
Sbjct: 163 PSPPQRAQRGDHSSREQGH--APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNIT 220

Query: 452 QQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE 493
           +QT + V+I R+   N     K   I  +P+    A ++I E
Sbjct: 221 KQTQSRVDIHRK--ENSGAAEKPVTIHATPEGTSEACRMILE 260


>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
          Length = 335

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 84/346 (24%), Positives = 146/346 (42%), Gaps = 51/346 (14%)

Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
           VG IIG+ GE + K++++SG ++ IS   G  PER ++L G   ++ KA  M+ D +   
Sbjct: 25  VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
                    ++    +      +++PA + G +IGKGG  IK+++E  G ++ +  D   
Sbjct: 83  ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139

Query: 276 NTNVDKPLRIIGDPYK----VQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-P 330
           N + ++ + I G P      V+Q C ++++ L +                  G+ +P  P
Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLETLSQSPP--------------KGVTIPYRP 184

Query: 331 RHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLL 390
           + S   VI   G+    IQ    +     Q D T   ++A               +    
Sbjct: 185 KPSSSPVIFAGGQAY-TIQGQYAI----PQPDLTKLHQLA---------------MQQSH 224

Query: 391 QSLRSGPPGPPGGPGMPPGGRGRGRG-QGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKA 449
             +  G  G  G     P  +G   G   +      E+T  IP    G +IGR G  +  
Sbjct: 225 FPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELT--IPNDLIGCIIGRQGAKINE 282

Query: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
           I Q +GA ++I+  +  + D   +   I GS   I  A+ LI  ++
Sbjct: 283 IRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 325



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 53/190 (27%), Positives = 83/190 (43%), Gaps = 29/190 (15%)

Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
           VG +IG+ GE +KK++ ++G RI   +  G  PE+I  + GP +    A  +I D L+  
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            S           PP                  +   +P  +CG +IG+GG  +K I + 
Sbjct: 83  ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126

Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512
           TGA V+++  + PN     +   I G PQ  I+  KQ+    +E     +   P    P 
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLE----TLSQSP----PK 176

Query: 513 GPMGPFNPGP 522
           G   P+ P P
Sbjct: 177 GVTIPYRPKP 186



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 25/73 (34%), Positives = 47/73 (64%)

Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205
           + E  +P+ ++G IIGR G +IN+I+Q SG +++I+    G  +R V++TG+  S+  A+
Sbjct: 259 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 318

Query: 206 MMLDDIVSRGRGG 218
            +++  +S   GG
Sbjct: 319 YLINVRLSSETGG 331



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%)

Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
           + ISS +       R  +T    VP    G +IG+GG +I +I++ +G +VQ++ D   L
Sbjct: 81  EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138

Query: 188 P---ERSVSLTGAPESV 201
           P   ER++++ G P+S+
Sbjct: 139 PNSTERAITIAGIPQSI 155



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 18/71 (25%), Positives = 31/71 (43%)

Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
           ++ +P   +G +IGR G  I +I+  +G +I+         ++   I G       A  +
Sbjct: 261 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 320

Query: 386 INDLLQSLRSG 396
           IN  L S   G
Sbjct: 321 INVRLSSETGG 331


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 91/325 (28%), Positives = 105/325 (32%), Gaps = 98/325 (30%)

Query: 396 GPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTG 455
           GPP PPG P  PP             P GG                         N+  G
Sbjct: 49  GPPPPPGKPQGPP-------------PQGG-------------------------NKPQG 70

Query: 456 AFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPM 515
                    PP G P       +G P Q D        K   P  P G  P GP P G  
Sbjct: 71  P--------PPPGKP-------QGPPPQGD--------KSRSPRSPPGK-PQGPPPQGGN 106

Query: 516 GPFNPGPFNQGPPGAPPHAG----GPP----PHQYPPQGWGNTYPQWQPPAPHDPSKAAA 567
            P  P P    P G PP  G    GPP    P   PPQG  +  P+  P  P  P     
Sbjct: 107 QPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG 166

Query: 568 AAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQ-PPPTGQSDYTKAWEEYY 626
                             QP GP P P      PP  G+ PQ PPP G+        +  
Sbjct: 167 -----------------NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKS 209

Query: 627 KKIGQQPQQPGAPPQQDYTKAW---EEYYKKQAQVATGGG--PGAPPGSQPDYSAAWAEY 681
           +     P +P  PP Q   +         K Q     GG    G PP  +P    A    
Sbjct: 210 RSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGS 269

Query: 682 YRQQAAYYGQTPGPGGPQPPPTQQG 706
             Q A    ++P PG PQ PP Q+G
Sbjct: 270 KSQSA----RSP-PGKPQGPPQQEG 289



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 76/245 (31%), Positives = 87/245 (35%), Gaps = 88/245 (35%)

Query: 501 PVGPGP-GGPGPAGPMGPFNP-GPFNQG------------PPGAPPHAG----GPPPHQY 542
           P GP P GG  P GP  P  P GP  QG            P G PP  G    GPPP   
Sbjct: 57  PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG 116

Query: 543 PPQG---WGNTYPQWQPPA--PHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPA 597
            PQG    G   PQ  PP   P  P      +  P +            PPG   GP P 
Sbjct: 117 KPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRS------------PPGKPQGPPPQ 164

Query: 598 -----PAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQP-------GAPPQQDYT 645
                   PP  G+P  PPP G               G++PQ P       G PPQ D +
Sbjct: 165 GGNQPQGPPPPPGKPQGPPPQG---------------GKKPQGPPPPGKPQGPPPQGDKS 209

Query: 646 KAWEEYYKKQAQVATGGGPGAPP--GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPT 703
           ++        +Q   G   G PP  G+QP                 G  P PG PQ PP 
Sbjct: 210 RS--------SQSPPGKPQGPPPQGGNQPQ----------------GPPPPPGKPQGPPP 245

Query: 704 QQGQQ 708
           Q G +
Sbjct: 246 QGGNK 250



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 68/224 (30%), Positives = 79/224 (35%), Gaps = 43/224 (19%)

Query: 502 VGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAG----GPP----PHQYPPQGWGNTYPQ 553
           +   P GP P G   P  P P    P G PP  G    GPP    P   PPQG  +  P+
Sbjct: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91

Query: 554 WQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAP----APAAPPAQGEPPQ 609
             P  P  P         P              PPG   GP P     P  PP  G+P  
Sbjct: 92  SPPGKPQGP--PPQGGNQPQGP---------PPPPGKPQGPPPQGGNRPQGPPPPGKPQG 140

Query: 610 PPPTGQSDYTKAW-----EEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGP 664
           PPP G    +        +    + G QPQ P  PP +      +   K Q     G   
Sbjct: 141 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200

Query: 665 GAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQ 708
           G PP  Q D S +             Q+P PG PQ PP Q G Q
Sbjct: 201 GPPP--QGDKSRS------------SQSP-PGKPQGPPPQGGNQ 229



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 81/252 (32%), Positives = 94/252 (37%), Gaps = 66/252 (26%)

Query: 396 GPPGPPGGP-GMPPGGRGRGRGQGNWG-----PPGGEMTFSIPTHKCGLVIG---RGGEN 446
           GPP PPG P G PP G  R +G    G     PP G+ + S P    G   G   +GG  
Sbjct: 110 GPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRS-PRSPPGKPQGPPPQGG-- 166

Query: 447 VKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGP 506
               NQ  G         PP G P       +G P Q         +K +GP  P    P
Sbjct: 167 ----NQPQGP-------PPPPGKP-------QGPPPQGG-------KKPQGP--PPPGKP 199

Query: 507 GGPGPAGPMGPFNPGPFNQGPPGAPPHAG----GPPPHQYPPQG---WGNTYPQWQPPA- 558
            GP P G     +  P  + P G PP  G    GPPP    PQG    G   PQ  PP  
Sbjct: 200 QGPPPQGDKSRSSQSPPGK-PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 258

Query: 559 -PHDP-----SKAAAAAADPNAAWAA--YYSHYYQQPPGPVPGPAPAPAAPPA------- 603
            P  P     SK+ +A + P           +  Q PP P  G    P APPA       
Sbjct: 259 KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP 318

Query: 604 ---QGEPPQPPP 612
              QG  P  PP
Sbjct: 319 RPPQGGRPSRPP 330



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 29/68 (42%), Positives = 30/68 (44%), Gaps = 12/68 (17%)

Query: 8   GPPPGP-----PPPAGGGGGAGGAGGGPPPGPPGAGDRG------GGGPGGGGP-GGGSA 55
           GPPP P     PPP GG    G    G P GPP  GD+        G P G  P GG   
Sbjct: 49  GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 108

Query: 56  GGPSQPPG 63
            GP  PPG
Sbjct: 109 QGPPPPPG 116



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 29/68 (42%), Positives = 30/68 (44%), Gaps = 12/68 (17%)

Query: 8   GPPPGP-----PPPAGGGGGAGGAGGGPPPGPPGAGDRG------GGGPGGGGP-GGGSA 55
           GPPP P     PPP GG    G    G P GPP  GD+        G P G  P GG   
Sbjct: 110 GPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 169

Query: 56  GGPSQPPG 63
            GP  PPG
Sbjct: 170 QGPPPPPG 177



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 31/74 (41%), Positives = 34/74 (45%), Gaps = 13/74 (17%)

Query: 7   GGPPPGPP--PPAGGGGGAGGAGGGP--PPGPP---GAGDRGGGGPGGGGPG------GG 53
           G PPPG P  PPA GG  +  A   P  P GPP   G   +G   P GG P        G
Sbjct: 253 GPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG 312

Query: 54  SAGGPSQPPGGGGP 67
              GP +PP GG P
Sbjct: 313 QPQGPPRPPQGGRP 326



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 31/73 (42%), Positives = 32/73 (43%), Gaps = 16/73 (21%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGG----GPPP-----GPPGAGDRG------GGGPGGGGP- 50
           G  P GPPPP G   G    GG    GPPP     GPP  GD+        G P G  P 
Sbjct: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQ 225

Query: 51  GGGSAGGPSQPPG 63
           GG    GP  PPG
Sbjct: 226 GGNQPQGPPPPPG 238



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 29/77 (37%), Positives = 29/77 (37%), Gaps = 16/77 (20%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGG-------GPGGGSAGGPS 59
           G  P GPPPP G   G    GG  P GPP  G   G    GG        P G   G P 
Sbjct: 227 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286

Query: 60  Q---------PPGGGGP 67
           Q         PP GG P
Sbjct: 287 QEGNNPQGPPPPAGGNP 303



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 43/130 (33%), Positives = 46/130 (35%), Gaps = 21/130 (16%)

Query: 2   SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPP-GAGDRGGGGPGGGGPGGGSAGGPSQ 60
           S  S  G P GPPP     GG    G  PPPG P G   +GG  P G  P     G P  
Sbjct: 211 SSQSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQG 262

Query: 61  PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNN---STPDFGFGGQKRQLEDGDQ 117
           PP  GG            Q AR    K  G      NN     P  G   Q+ Q     Q
Sbjct: 263 PPAQGG---------SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 313

Query: 118 PESKKLASQG 127
           P+      QG
Sbjct: 314 PQGPPRPPQG 323



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/62 (41%), Positives = 29/62 (46%), Gaps = 8/62 (12%)

Query: 7   GGPPPGP---PPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
           G PPPG    PPP G    +  +  G P GPP    +GG  P G  P  G   GP  PP 
Sbjct: 70  GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGP--PPQ 124

Query: 64  GG 65
           GG
Sbjct: 125 GG 126



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/62 (41%), Positives = 29/62 (46%), Gaps = 8/62 (12%)

Query: 7   GGPPPGP---PPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
           G PPPG    PPP G    +  +  G P GPP    +GG  P G  P  G   GP  PP 
Sbjct: 131 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGP--PPQ 185

Query: 64  GG 65
           GG
Sbjct: 186 GG 187



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 26/60 (43%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 2   SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPP-GAGDRGGGGPGGGGPGGGSAGGPSQ 60
           S  S  G P GPPP     GG    G  PPPG P G   +GG  P G  P G   G P Q
Sbjct: 89  SPRSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQ 144



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 26/60 (43%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 2   SDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPG-PPGAGDRGGGGPGGGGPGGGSAGGPSQ 60
           S  S  G P GPPP     GG    G  PPPG P G   +GG  P G  P G   G P Q
Sbjct: 150 SPRSPPGKPQGPPPQ----GGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ 205



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 23/54 (42%), Positives = 24/54 (44%), Gaps = 5/54 (9%)

Query: 8  GPPPGPPPPAGGGGGAGGAGGGPPPGPP-GAGDRGGGGPGGGGPGGGSAGGPSQ 60
          G P GP P     GG    G  PPPG P G   +GG  P G  P G   G P Q
Sbjct: 34 GNPQGPSPQ----GGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83


>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
          Length = 331

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 81/342 (23%), Positives = 143/342 (41%), Gaps = 47/342 (13%)

Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
           VG IIG+ GE + K++++SG ++ IS   G  PER ++L G   ++ KA  M+ D +   
Sbjct: 25  VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
                    ++    +      +++PA + G +IGKGG  IK+++E  G ++ +  D   
Sbjct: 83  ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139

Query: 276 NTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSV 334
           N + ++ + I G P  + +  + +  ++ E                  G+ +P  P+ S 
Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLESPP--------------KGVTIPYRPKPSS 184

Query: 335 GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394
             VI   G+    IQ    +     Q D T   ++A               +      + 
Sbjct: 185 SPVIFAGGQAY-TIQGQYAI----PQPDLTKLHQLA---------------MQQSHFPMT 224

Query: 395 SGPPGPPGGPGMPPGGRGRGRG-QGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            G  G  G     P  +G   G   +      E+T  IP    G +IGR G  +  I Q 
Sbjct: 225 HGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELT--IPNDLIGCIIGRQGAKINEIRQM 282

Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
           +GA ++I+  +  + D   +   I GS   I  A+ LI  ++
Sbjct: 283 SGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 321



 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 53/190 (27%), Positives = 82/190 (43%), Gaps = 33/190 (17%)

Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
           VG +IG+ GE +KK++ ++G RI   +  G  PE+I  + GP +    A  +I D L+  
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            S           PP                  +   +P  +CG +IG+GG  +K I + 
Sbjct: 83  ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126

Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512
           TGA V+++  + PN     +   I G PQ  I+  KQ+    +E P            P 
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESP------------PK 172

Query: 513 GPMGPFNPGP 522
           G   P+ P P
Sbjct: 173 GVTIPYRPKP 182



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 25/73 (34%), Positives = 47/73 (64%)

Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205
           + E  +P+ ++G IIGR G +IN+I+Q SG +++I+    G  +R V++TG+  S+  A+
Sbjct: 255 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 314

Query: 206 MMLDDIVSRGRGG 218
            +++  +S   GG
Sbjct: 315 YLINVRLSSETGG 327



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%)

Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
           + ISS +       R  +T    VP    G +IG+GG +I +I++ +G +VQ++ D   L
Sbjct: 81  EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138

Query: 188 P---ERSVSLTGAPESV 201
           P   ER++++ G P+S+
Sbjct: 139 PNSTERAITIAGIPQSI 155



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 18/71 (25%), Positives = 31/71 (43%)

Query: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
           ++ +P   +G +IGR G  I +I+  +G +I+         ++   I G       A  +
Sbjct: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 316

Query: 386 INDLLQSLRSG 396
           IN  L S   G
Sbjct: 317 INVRLSSETGG 327


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 101/355 (28%), Positives = 121/355 (34%), Gaps = 91/355 (25%)

Query: 396  GPPGPPGGPGMP-----PGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGE 445
            GPPGP G PG+P     PG  GR   +G  GPPG     GE  F++P          G  
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP----------GPP 759

Query: 446  NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG 505
                +    GA       L P GD        RG P       +   + + GP   VGP 
Sbjct: 760  GPPGLPGFKGA-------LGPKGD--------RGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 506  PGGPGPAGPMG------------PFNPGPFNQ----------GPPGAPP-HAGGPPPHQY 542
             G PGP GP G            P  PGP  Q          G PG P     GPP  + 
Sbjct: 805  -GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863

Query: 543  PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPP 602
             P   G   P   P +P  P KA A+                  PPGP PGP   P    
Sbjct: 864  SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG-----PPGP-PGPLGIPGRSG 917

Query: 603  A---------QGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK 653
                      QG+P  P PTG+           K    +P  PG P   D          
Sbjct: 918  VPGLKGDDGLQGQPGLPGPTGE-----------KGSKGEPGLPGPPGPMD-----PNLLG 961

Query: 654  KQAQVATGGGPGAPPGSQP-DYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQ 707
             + +    G PG P  S P  Y     +  +   +     PGP GP+  P   GQ
Sbjct: 962  SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 190/754 (25%), Positives = 243/754 (32%), Gaps = 180/754 (23%)

Query: 11  PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69
           PGPP P G  G  G  G    PG PG  G  G  GP G     G+ G    P   G PG+
Sbjct: 83  PGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142

Query: 70  RKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDS 129
           +       +   +       G+  + + +S P     G K        P  + L      
Sbjct: 143 QGPPGPPGIPGMK-------GEPGSIIMSSLP-----GPKGNPGYPGPPGIQGLPGP-TG 189

Query: 130 ISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPE 189
           I   +GP  PP           P G  GL   +G   +N  Q   G K +      G P 
Sbjct: 190 IPGPIGPPGPPGLMG-------PPGPPGLPGPKGNMGLN-FQGPKGEKGEQGLQ--GPP- 238

Query: 190 RSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVI 249
                 G P  + + K  +D    +G  G PG   D    G  G    I  P G  G   
Sbjct: 239 ------GPPGQISEQKRPIDVEFQKGDQGLPG---DRGPPGPPG----IRGPPGPPGGEK 285

Query: 250 GKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDP-YKVQQACEMVMDILRERDQ 308
           G+ GE     Q   G +    +DG +N     P  + GDP Y  +          R+ ++
Sbjct: 286 GEKGE-----QGEPGKRGKPGKDG-ENGQPGIP-GLPGDPGYPGEPG--------RDGEK 330

Query: 309 GGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEM-IKKIQNDAGVRIQFKQDDGTGPE 367
           G  GD    G        + +PR   G+ IG  G + +  +  + G R            
Sbjct: 331 GQKGDTGPPGPP-----GLVIPRPGTGITIGEKGNIGLPGLPGEKGER------------ 373

Query: 368 KIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPG----GPGMPPGGRGRGRGQGNWGPP 423
               I GPP                   G PGPPG    GP  PPG  G    +G+ GPP
Sbjct: 374 GFPGIQGPP-------------------GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414

Query: 424 GGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSP-- 481
           G     SIP    GL    G   +       G  +  S ++   G P        GSP  
Sbjct: 415 G----ISIPGPP-GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP-----GSPGD 464

Query: 482 -----------QQIDHAKQLIEEKIEGPLCPVGPG-PGGPGPAGPMG-PFNPGPFNQ--- 525
                       + D     I   I GP  P  PG PG PGP G +G P   G   Q   
Sbjct: 465 KGLQGEQGVKGDKGDTCFNCIGTGISGP--PGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 526 -GPPGAPPHAGGPPPHQYP------------PQGWGNTYPQWQPPAPHDPSKAAAAAADP 572
            GP G P   G P    +P            P   G+      P AP  P        D 
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 573 NAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE--PPQPP-------------PTGQSD 617
                          PG +PGP   P     +GE  PP  P             P G   
Sbjct: 583 L--------------PG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627

Query: 618 YTKAWEEYYKKIGQQPQQPGAP-----PQQDYTKAWEEYYK----KQAQVATGGGPGAPP 668
                E+  + +   P QPG P     P Q  T+  +        +   V   G PG P 
Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP- 686

Query: 669 GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPP 702
             QP                 G  PGP GP+  P
Sbjct: 687 -GQPGLPGIPGSKGEPGIPGIG-LPGPPGPKGFP 718



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 205/819 (25%), Positives = 262/819 (31%), Gaps = 228/819 (27%)

Query: 10  PPGPPPPAGGGGGAGGAGGGP-----------PPGPPGA--------------------G 38
           PPGPP   G  G  G    GP           PPGPPG                     G
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264

Query: 39  DRGGGGPGG-----GGPGG--GSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGD 91
           DRG  GP G     G PGG  G  G   +P   G PG                  K G +
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG------------------KDGEN 306

Query: 92  AATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRV 151
               +     D G+ G+  +  DG++ +       G       G + P P T +T   + 
Sbjct: 307 GQPGIPGLPGDPGYPGEPGR--DGEKGQKGDTGPPGPP-----GLVIPRPGTGITIGEKG 359

Query: 152 PDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDI 211
             G+ GL   +G      IQ   G          G P  +V     P      +      
Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLP--------GPPGAAVMGPPGPPGFPGERGQ---- 407

Query: 212 VSRGRGGPPGQFHDNANG--GQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMIL 269
             +G  GPPG       G  GQ G    +  P G AG  I    E  +            
Sbjct: 408 --KGDEGPPGISIPGPPGLDGQPGA-PGLPGPPGPAGPHIPPSDEICEPGPP-------- 456

Query: 270 IQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR-IGGGIDVP 328
              G   +  DK L                     + +QG  GD+ +     IG GI  P
Sbjct: 457 ---GPPGSPGDKGL---------------------QGEQGVKGDKGDTCFNCIGTGISGP 492

Query: 329 VPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDR--CEHAARII 386
             +  +  + G  G +        G + +  Q   TGP+ +  I G P       +    
Sbjct: 493 PGQPGLPGLPGPPGSL-----GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEP 547

Query: 387 NDLL-------QSLRSGPPGPPGGPGMP-----------PGGRGRGRG---QGNWGPPGG 425
            D+L            G PG PG PG+P           PG +G   G   +G  GPPG 
Sbjct: 548 GDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN 607

Query: 426 EMTFSIPTH----------KCGLVIGRGGENVKAINQQTGAFVEISRQLP-PNGDPNFKL 474
                +P +            G V  +G + V     Q G        +P P GDP  + 
Sbjct: 608 PGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG--------IPGPKGDPG-QT 658

Query: 475 FIIRGSPQQIDHAKQLIEEKIEG-PLCPVGPG-PGGPGPAGPMG------PFNPGPFN-- 524
               G P    +  +  +  + G P  P  PG PG PG  G  G      P  PGP    
Sbjct: 659 ITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFP 718

Query: 525 --QGPPGAPPHAG-----GPP-PHQYP-PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAA 575
              GPPGAP   G     GPP P  +P P+G     P +  P P  P            A
Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG----EPGFALPGPPGPPGLPGF----KGA 770

Query: 576 WAAYYSHYYQQPPGP--------VPGP--------APAPAAPP------AQGEPPQPP-- 611
                   +  PPGP        +PGP         P P  PP       QG PP PP  
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG-PPGPPGI 829

Query: 612 --PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPG 669
             P GQ             I  +   PG PP  D      E  +    +    GP  PPG
Sbjct: 830 PGPIGQPG--------LHGIPGEKGDPG-PPGLDVPGPPGE--RGSPGIPGAPGPIGPPG 878

Query: 670 SQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQG 706
           S      A A  +       G    PGP GP   P + G
Sbjct: 879 SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 101/346 (29%), Positives = 123/346 (35%), Gaps = 55/346 (15%)

Query: 395  SGPPGPPGGPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGEN--- 446
            SGPPG PG PG  PG  G G   G  GPPG     G+     P  + G     G  N   
Sbjct: 1136 SGPPGNPGLPG-EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194

Query: 447  --VKAINQQTG----AFVEISRQLP-PNGDPNFKLFI-IRGSPQQIDHAKQLIEEKIEGP 498
              +  ++ Q G      +  +  LP P G+P F  F  ++G P         +E   +G 
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGP-KGN 1253

Query: 499  LCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAG-----GPPPHQYPPQGWGNTYPQ 553
              P GP PG PGP G  G   PGP  +GPPG P + G     G P     P   G    Q
Sbjct: 1254 PGPQGP-PGRPGPTGFQG--LPGP--EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1308

Query: 554  WQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPP-- 611
              P    +P +        +            + P  VPG A  P   P    PP PP  
Sbjct: 1309 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA-GPEGEPGLIGPPGPPGL 1367

Query: 612  --PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAP-P 668
              P+GQS   K  +     I  QP   G P  Q            Q      G PG P  
Sbjct: 1368 PGPSGQSIIIKG-DAGPPGIPGQPGLKGLPGPQG----------PQGLPGPTGPPGDPGR 1416

Query: 669  GSQPDYSAAWAEYYRQQAAYYGQ--------TPGPGGPQPPPTQQG 706
               P +  A     +      GQ         PGP G Q PP   G
Sbjct: 1417 NGLPGFDGAGGR--KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 176/686 (25%), Positives = 216/686 (31%), Gaps = 172/686 (25%)

Query: 10  PPGPPPPAGGGGGAG--------GAGGGPP-PGPPGAGDRGGGGPGG-----GGPGGGSA 55
           PPGPP   G  G  G        G  G P  PGPPG   +G  GP G     G PG    
Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGI--QGLPGPTGIPGPIGPPGPPGL 202

Query: 56  GGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDG 115
            GP  PPG  GP   K       Q  +    + G              G  G   Q+ + 
Sbjct: 203 MGPPGPPGLPGP---KGNMGLNFQGPKGEKGEQGLQ------------GPPGPPGQISEQ 247

Query: 116 DQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSG 175
            +P   +       +    GP  PP         R P G  G   G  GEQ    ++   
Sbjct: 248 KRPIDVEFQKGDQGLPGDRGPPGPP-------GIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 176 CK--VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNG 233
            K      P   GLP       G P                GR G  GQ  D    G  G
Sbjct: 301 GKDGENGQPGIPGLP-GDPGYPGEP----------------GRDGEKGQKGDTGPPGPPG 343

Query: 234 TVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKV 292
               ++IP    G+ IG+ G          G+  +  + G +    +  P  + G P   
Sbjct: 344 ----LVIPRPGTGITIGEKG--------NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391

Query: 293 QQACEMVMDILRERDQGGFGDRNEYGSRIGG--GID-------VPVPRHSVGVVIGRSGE 343
                       ER Q   GD    G  I G  G+D       +P P    G  I  S E
Sbjct: 392 VMGPPGPPGFPGERGQK--GDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 344 MI-------------KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLL 390
           +              K +Q + GV    K D G             D C +        +
Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGV----KGDKG-------------DTCFNC-------I 485

Query: 391 QSLRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVK 448
            +  SGPPG PG PG+  PPG  G    +G  G  G      +P    G+    G     
Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP----GIPGAPGAPGFP 541

Query: 449 AINQQTGAFVEI------SRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE------ 496
               + G  +          +L   G P   L  + G+P Q D    L   K E      
Sbjct: 542 GSKGEPGDILTFPGMKGDKGELGSPGAPG--LPGLPGTPGQ-DGLPGLPGPKGEPGGITF 598

Query: 497 ----GPLCPVGPG-PGGPGPAGPMGPFN---PGPF----------NQGPPGAPPHAGGP- 537
               GP  P  PG PG PG  GPMGP     PGP           N G PG P   G P 
Sbjct: 599 KGERGP--PGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656

Query: 538 -----PPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGP-- 590
                P     P   G       P  P  P +        +             PPGP  
Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716

Query: 591 ---VPGPAPAPAAPPAQG--EPPQPP 611
              +PGP  AP  P   G   PP PP
Sbjct: 717 FPGIPGPPGAPGTPGRIGLEGPPGPP 742



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 79/282 (28%), Positives = 92/282 (32%), Gaps = 80/282 (28%)

Query: 396  GPPGPPGGPGMPPGGRGRGRGQ-GNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKA 449
            GPPGP G PG+P        GQ G  GPPG     G+M F  P          G      
Sbjct: 1003 GPPGPKGNPGLP--------GQPGLIGPPGLKGTIGDMGFPGPQGV------EGPPGPSG 1048

Query: 450  INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDH-------AKQLIEEKIEGPLCPV 502
            +  Q G+   +  Q    GDP      + G P                I+  +  P  P 
Sbjct: 1049 VPGQPGS-PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG 1107

Query: 503  GPG-------------PGGPGPAGPMG----PFNPG-PFNQGPPGAPPHAG--GPPPHQY 542
             PG             PG PGP GP G    P NPG P   GP G   H G  GPP  + 
Sbjct: 1108 LPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKG 1167

Query: 543  PP-----------------QGWGNTYPQWQP---------PAPHDPSKAAAAAADPNAAW 576
             P                  G+GN  P   P           P  P             +
Sbjct: 1168 KPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF 1227

Query: 577  AAYYSHYYQQPPGPVPGPAPAPAAPPA----QGEPPQPPPTG 614
              +     Q PPGP   P PA   P      QG P +P PTG
Sbjct: 1228 HGFPG--VQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTG 1267



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 89/340 (26%), Positives = 105/340 (30%), Gaps = 97/340 (28%)

Query: 396  GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447
            GP GPPG PG+P        PG +G     G  GPPG      IP        GR G  V
Sbjct: 872  GPIGPPGSPGLPGKAGASGFPGTKGE---MGMMGPPGPPGPLGIP--------GRSG--V 918

Query: 448  KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP--G 505
              +    G                     ++G P             + GP    G    
Sbjct: 919  PGLKGDDG---------------------LQGQP------------GLPGPTGEKGSKGE 945

Query: 506  PGGPGPAGPMGPFNPGPFNQ-GPPGAP--PHAGGPPPHQYPPQGWGNTYPQWQP--PAPH 560
            PG PGP GPM P   G   + G PG P  P   GP  +Q  P   G      QP  P P 
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 561  DPSKAAAAAADPNAAWAAYYSHYYQQP--PGP-----VPGPAPAPAAPPAQGEPPQPPPT 613
             P         P                 PGP      PGP+  P  P + G P Q    
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 614  GQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAP--PGS- 670
            G    +            +P  PG P               +  V   G PG P  PG+ 
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGI----------KGSVGDPGLPGLPGTPGAK 1115

Query: 671  -QPDYSAAWAEYYRQQAAYYGQTPGPGGPQ---PPPTQQG 706
             QP                +  TPGP GP+    PP   G
Sbjct: 1116 GQPGLPG------------FPGTPGPPGPKGISGPPGNPG 1143



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 95/358 (26%), Positives = 114/358 (31%), Gaps = 72/358 (20%)

Query: 365 GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGP-- 422
           GP  I  + G P            ++ S   GP G PG PG PPG +G     G  GP  
Sbjct: 147 GPPGIPGMKGEP----------GSIIMSSLPGPKGNPGYPG-PPGIQGLPGPTGIPGPIG 195

Query: 423 PGGEMTFSIPTHKCGLVIGRG--GENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS 480
           P G      P    GL   +G  G N +    + G   E   Q PP            G 
Sbjct: 196 PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG---EQGLQGPP------------GP 240

Query: 481 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH 540
           P QI   K+ I+ + +     +    G PGP G  GP  PGP   G  G     G P   
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP--PGP-PGGEKGEKGEQGEPGKR 297

Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA 600
             P +   N  P   P  P DP        D               PPGP     P P  
Sbjct: 298 GKPGKDGENGQP-GIPGLPGDPGYPGEPGRDGEKGQKGDTG-----PPGPPGLVIPRPGT 351

Query: 601 PPAQGE------PPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK- 653
               GE      P  P   G        E  +  I   P  PG P            +  
Sbjct: 352 GITIGEKGNIGLPGLPGEKG--------ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403

Query: 654 KQAQVATGGGPG----APPG--SQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQ 705
           ++ Q    G PG     PPG   QP             A      PGP GP  PP+ +
Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPG------------APGLPGPPGPAGPHIPPSDE 449



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 28/63 (44%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69
            PGPP P G  G  G  G   PPG  G  GD G  GP G     G +G P QP   G PG 
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061

Query: 70   RKD 72
            + D
Sbjct: 1062 KGD 1064



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/76 (43%), Positives = 34/76 (44%), Gaps = 14/76 (18%)

Query: 8    GPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRG-GGGPGGGGPGGGS 54
            GPP     PG P P GGGG  G  G     G PG       AG +G  G PG G PG   
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196

Query: 55   AGGPSQPPGGGG-PGI 69
              G S   G GG PGI
Sbjct: 1197 LPGLSGQKGDGGLPGI 1212



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 30/69 (43%), Positives = 32/69 (46%), Gaps = 7/69 (10%)

Query: 6    TGGPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPS 59
            T GPP      GPP   G  G  G  GGG  PG PG  G++G  G  G     G  G P 
Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 60   QPPGGGGPG 68
            Q PG G PG
Sbjct: 1186 Q-PGFGNPG 1193



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 11/76 (14%)

Query: 8   GPP----PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
           GPP    PGPP   G  G  G  G   PPG PG   + G     G  G     GP  PPG
Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908

Query: 64  -------GGGPGIRKD 72
                   G PG++ D
Sbjct: 909 PLGIPGRSGVPGLKGD 924



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 31/72 (43%), Positives = 34/72 (47%), Gaps = 9/72 (12%)

Query: 10   PPGPPPPAGGG--GGAGGAGGGPPPGPPG-AGDRGGGGPGG--GGPGG----GSAGGPSQ 60
            PPGPP   G    G  G  G   PPG PG  G +G  GP G  G PG     G  G P Q
Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQ 1295

Query: 61   PPGGGGPGIRKD 72
            P   G PG++ D
Sbjct: 1296 PGLPGLPGLKGD 1307



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 61/216 (28%), Positives = 78/216 (36%), Gaps = 51/216 (23%)

Query: 504 PG-PGGPGPAGPMGPFN----------PGPFN-QGP------------PGAPPHAGGPPP 539
           PG PG PGP GP GP            PGP   +GP            PG P H G P P
Sbjct: 59  PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP 118

Query: 540 HQYP-----------PQGWGNTYPQWQPPAPHDPS-KAAAAAADPNAAWAAYYSHYYQQP 587
              P           P   G    Q  P  P  P  K    +   ++      +  Y  P
Sbjct: 119 QGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP 178

Query: 588 PG--------PVPGPAPAPAAPPAQGEPPQPP--PTGQSDYTKAWEEYYKKIGQQPQQ-- 635
           PG         +PGP   P  PP    PP PP  P  + +    ++    + G+Q  Q  
Sbjct: 179 PGIQGLPGPTGIPGPI-GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237

Query: 636 PGAPPQ-QDYTKAWEEYYKKQAQVATGG-GPGAPPG 669
           PG P Q  +  +  +  ++K  Q   G  GP  PPG
Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 26/57 (45%), Positives = 27/57 (47%), Gaps = 7/57 (12%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGP 67
            PG P P G  G  G  G   PPGPPG+      GP   GP G    GP  PPG  GP
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGS-----PGPALEGPKGNP--GPQGPPGRPGP 1265



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/75 (42%), Positives = 35/75 (46%), Gaps = 17/75 (22%)

Query: 12   GPPPPAGGGGGAG--GAGGGPPPGPPG-AGDRGGGG-------PGGGGPGG-----GSAG 56
            G P PAG  G  G  G G   PPG PG +G +G GG       PG  GP G     G  G
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 57   --GPSQPPGGGGPGI 69
              GP  PPG  GP +
Sbjct: 1233 VQGPPGPPGSPGPAL 1247



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 28/62 (45%), Positives = 29/62 (46%), Gaps = 4/62 (6%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGG-PGGGGP--GGGSAGGPSQPPGGGG 66
            PG P   G  G  G  G   PPGP G +G  G  G PG  GP  GGG  G P  P   G 
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168

Query: 67   PG 68
            PG
Sbjct: 1169 PG 1170



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 28/68 (41%), Positives = 31/68 (45%), Gaps = 7/68 (10%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPG----GGSAGGPSQPP 62
            P GPP   G GG  G  G    PG PG  G +G  GP G  G PG     G  G P  P 
Sbjct: 1274 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1333

Query: 63   GGGGPGIR 70
              G PG++
Sbjct: 1334 VPGFPGMK 1341



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 28/71 (39%), Positives = 31/71 (43%), Gaps = 12/71 (16%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGP------PGAGDRGGGG----PGGGGPGG--GSAGGP 58
            PG P P G  G  G  G   PPGP         G++G  G    PG  GP G  G  G P
Sbjct: 931  PGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP 990

Query: 59   SQPPGGGGPGI 69
             QP   G PG+
Sbjct: 991  GQPGLSGQPGL 1001



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 31/73 (42%), Positives = 32/73 (43%), Gaps = 19/73 (26%)

Query: 8   GPPPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGGGGPGG----GGPG-GGSAGGP 58
           GPP  P PP        GA    PPGPPG     G +G  GP G    G PG  G  G P
Sbjct: 380 GPPGLPGPP--------GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431

Query: 59  S--QPPGGGGPGI 69
               PPG  GP I
Sbjct: 432 GLPGPPGPAGPHI 444



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 32/78 (41%), Positives = 33/78 (42%), Gaps = 19/78 (24%)

Query: 8   GPPP----GPPPPAGGGGGAGGAGG-GPP----PGPPGAGDRGG--GGPGGGGPGGG--- 53
           GPP     GPP P G  G  G  G  GPP    PGPPG   + G  G PG  GP G    
Sbjct: 386 GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 54  -----SAGGPSQPPGGGG 66
                   GP  PPG  G
Sbjct: 446 PSDEICEPGPPGPPGSPG 463



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 67/247 (27%), Positives = 76/247 (30%), Gaps = 49/247 (19%)

Query: 396  GPPGPPGGPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKAI 450
            GPPGPPG PG  P   G     G  GPPG     G      P    GL  G GG   +  
Sbjct: 1235 GPPGPPGSPG--PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLP-GNGGIKGEKG 1291

Query: 451  NQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEG-PLCPVGPGPGG- 508
            N        +       G P      ++G+P +        +  + G P  P   GP G 
Sbjct: 1292 NPGQPGLPGLPGLKGDQGPPG-----LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV 1346

Query: 509  ---------------PGPAGPMGPFNPGPF---NQGPPGAPPHAG--GPPPHQYPPQGWG 548
                           PGP G  GP         + GPPG P   G  G P  Q P    G
Sbjct: 1347 PGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1406

Query: 549  NTYPQWQPPAPHDP--SKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE 606
             T P   P     P    A     DP              P  P       P  P     
Sbjct: 1407 PTGPPGDPGRNGLPGFDGAGGRKGDPGL------------PGQPGTRGLDGPPGPDGLQG 1454

Query: 607  PPQPPPT 613
            PP PP T
Sbjct: 1455 PPGPPGT 1461



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 32/71 (45%), Positives = 33/71 (46%), Gaps = 9/71 (12%)

Query: 8   GPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRG-----GGGPG-GGGPG-GGSAGGP 58
           GPP  GPP P G  G  G AG    PG PG  GD G      G PG  G PG  G  G P
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680

Query: 59  SQPPGGGGPGI 69
             P   G PG+
Sbjct: 681 GDPGLPGQPGL 691



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 29/63 (46%), Positives = 29/63 (46%), Gaps = 7/63 (11%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGG-PGGGSAGGPSQPPG-GG 65
            PPG P P G  G  G  G   PPG PG G   G  G PG  G PG     G   PPG  G
Sbjct: 1259 PPGRPGPTGFQGLPGPEG---PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQG 1315

Query: 66   GPG 68
             PG
Sbjct: 1316 NPG 1318



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 31/72 (43%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 3   DYSTGGPP--PGPP--PPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSA 55
           D    G P  PG P  P   G  G  G  G   PGPPG  G  G  GP G  G PG    
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 56  GGPSQPPGGGGP 67
            GP  PPG  GP
Sbjct: 736 EGPPGPPGFPGP 747



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 34/87 (39%), Positives = 35/87 (40%), Gaps = 27/87 (31%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGP----------PPGPPG-------------AGDRG-G 42
           G P P  PP + G  G  GA G P          PPGPPG              GD G  
Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 43  GGPGGGGPGG--GSAGGPSQPPGGGGP 67
           G PG  GP G  GS G P   PG  GP
Sbjct: 929 GQPGLPGPTGEKGSKGEPGL-PGPPGP 954



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 29/65 (44%), Positives = 29/65 (44%), Gaps = 5/65 (7%)

Query: 8    GPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63
            GPP  PG P   G  G  G  G   P GPPG   R G  PG  G GG  G  G P QP  
Sbjct: 1382 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGL-PGFDGAGGRKGDPGLPGQPGT 1440

Query: 64   GGGPG 68
             G  G
Sbjct: 1441 RGLDG 1445



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 27/60 (45%), Positives = 27/60 (45%), Gaps = 12/60 (20%)

Query: 10   PPGPPPPAGGGG-----GAGGAGGGPP-PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
            P GPP   G  G     GAGG  G P  PG PG   RG  GP    PG     GP  PPG
Sbjct: 1407 PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT--RGLDGP----PGPDGLQGPPGPPG 1460



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 27/65 (41%), Positives = 28/65 (43%), Gaps = 10/65 (15%)

Query: 10   PPGPPPPAGGGGGA----GGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63
            PPGPP   G  G +    G AG    PG PG      G PG  GP G  G  G P  P  
Sbjct: 1361 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLK----GLPGPQGPQGLPGPTGPPGDPGR 1416

Query: 64   GGGPG 68
             G PG
Sbjct: 1417 NGLPG 1421



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 29/64 (45%), Positives = 30/64 (46%), Gaps = 15/64 (23%)

Query: 6   TGGPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGG--GSAG--GPS 59
           TG P P GPP P G  G         PPGPPG  G +G  G    GP G  G  G  GP 
Sbjct: 188 TGIPGPIGPPGPPGLMG---------PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP 238

Query: 60  QPPG 63
            PPG
Sbjct: 239 GPPG 242



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 27/63 (42%), Positives = 29/63 (46%), Gaps = 6/63 (9%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQP--PGG 64
            PG P   G  G  G  G    PG PGA  + G  G PG  GP G  G +G P  P  PG 
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE 1147

Query: 65   GGP 67
             GP
Sbjct: 1148 PGP 1150



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 45/170 (26%), Positives = 53/170 (31%), Gaps = 64/170 (37%)

Query: 365  GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--PGGRGRGRGQGNWGP 422
            GPE    ++GPP            ++    +GPPG PG PG+   PG +G     G  GP
Sbjct: 1351 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1410

Query: 423  PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQ 482
            PG      +P        G GG                       GDP            
Sbjct: 1411 PGDPGRNGLPGFD-----GAGGR---------------------KGDPGL---------- 1434

Query: 483  QIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFN-QGPPGAP 531
                                   PG PG  G  GP  PGP   QGPPG P
Sbjct: 1435 -----------------------PGQPGTRGLDGP--PGPDGLQGPPGPP 1459



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 31/78 (39%), Positives = 32/78 (41%), Gaps = 17/78 (21%)

Query: 10   PPGPPPPAG------GGGGAGGAGGGP-------PPGPPGAGDRGG--GGPGGGG-PGGG 53
            PPG P P+G      G  G  G  G P       P GP G     G  G PG  G PG  
Sbjct: 1364 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1423

Query: 54   SAGGPSQPPG-GGGPGIR 70
             AGG    PG  G PG R
Sbjct: 1424 GAGGRKGDPGLPGQPGTR 1441



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 25/60 (41%), Positives = 25/60 (41%), Gaps = 3/60 (5%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPG-GGGPGGGSAGGPSQPPGGGGP 67
            PGP  P G  G  G  G     G PG    GG  G PG  G PG     GP  P G  GP
Sbjct: 1396 PGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGP 1455



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 31/79 (39%), Positives = 31/79 (39%), Gaps = 18/79 (22%)

Query: 3   DYSTGGPPP--GPPPPAGGGGGAGGAGGGP-------------PPGPPGA-GDRG-GGGP 45
           D    GPP   GPP P GG  G  G  G P              PG PG  GD G  G P
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324

Query: 46  GGGGPGGGSAG-GPSQPPG 63
           G  G  G     GP  PPG
Sbjct: 325 GRDGEKGQKGDTGPPGPPG 343



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 11/71 (15%)

Query: 8   GPP--PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGG-PGGGGPGGGSAGG 57
           GPP  PG P   G  G  G  G G PPGP G       AG+ G  G PG  G  G +   
Sbjct: 603 GPPGNPGLPGLPGNIGPMGPPGFG-PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661

Query: 58  PSQPPGGGGPG 68
           P +P   G PG
Sbjct: 662 PGKPGLPGNPG 672



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 6/65 (9%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGA----GDRGGGGPGGGGPGG--GSAGGPSQPPGGG 65
            G P P G  G  G +G    PG PG     GD+G  G    G  G  G  G P  P   G
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092

Query: 66   GPGIR 70
             PGI+
Sbjct: 1093 NPGIK 1097



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 29/78 (37%), Positives = 32/78 (41%), Gaps = 18/78 (23%)

Query: 11   PGPPPPAGGG--GGAGGAGGGPPPGPPGA----------GDRG----GGGPGGGGPGG-- 52
            PGPP P      G  G  G    PG PG           GD G     G PG  GP G  
Sbjct: 949  PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008

Query: 53   GSAGGPSQPPGGGGPGIR 70
            G+ G P QP   G PG++
Sbjct: 1009 GNPGLPGQPGLIGPPGLK 1026



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 27/64 (42%), Positives = 29/64 (45%), Gaps = 6/64 (9%)

Query: 11   PGPP--PPAGGGGGAGGAGGGPP-PGPPGAGDRGG--GGPG-GGGPGGGSAGGPSQPPGG 64
            PGPP  P   G  G GG  G P  PG PG     G  G PG  G PG   + GP+     
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 65   GGPG 68
            G PG
Sbjct: 1252 GNPG 1255



 Score = 33.5 bits (75), Expect = 0.70
 Identities = 34/89 (38%), Positives = 35/89 (39%), Gaps = 28/89 (31%)

Query: 8   GPP--------PGPPPPAG--------GGGGAGGAGGGPP-PGPPGA----GDRGGGG-- 44
           GPP        PGPP   G        G  GA G  G P  PG PGA    G +G  G  
Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI 550

Query: 45  ---PGGGGPGG--GSAGGPSQPPGGGGPG 68
              PG  G  G  GS G P  P   G PG
Sbjct: 551 LTFPGMKGDKGELGSPGAPGLPGLPGTPG 579



 Score = 33.5 bits (75), Expect = 0.70
 Identities = 25/66 (37%), Positives = 27/66 (40%), Gaps = 6/66 (9%)

Query: 10   PPGPPPPAGGGGGAGGAG-GGPP-----PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
            PPG     G  G  G  G  GPP     PG PG+    G     G PG  S G P  P  
Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081

Query: 64   GGGPGI 69
             G PG+
Sbjct: 1082 KGEPGL 1087



 Score = 33.1 bits (74), Expect = 0.92
 Identities = 28/81 (34%), Positives = 31/81 (38%), Gaps = 21/81 (25%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGG------PGGGGPGG----------- 52
            PGP    G  G +G  G    PG PG  GD+G  G      PG  GP G           
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094

Query: 53   ---GSAGGPSQPPGGGGPGIR 70
               GS G P  P   G PG +
Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAK 1115



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 21/58 (36%), Positives = 21/58 (36%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGP 67
            P G P   G  G  G  G    PG PG     G     G PG     GP  P G  GP
Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 12/72 (16%)

Query: 10  PPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGG-GGPGGGGPGG-------GSAGG 57
           PPGP    G  G  G  G     G PG     G++G  G PG  GP G       GS G 
Sbjct: 906 PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965

Query: 58  PSQPPGGGGPGI 69
             +P   G PG+
Sbjct: 966 KGEPGLPGIPGV 977



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 6/65 (9%)

Query: 11   PGPPPPAGGGGGAGGAGGGPP--PGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGG 64
            PG P   G  G  G +  G P  PGP G     G  G PG  G  G  G  G P  P   
Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115

Query: 65   GGPGI 69
            G PG+
Sbjct: 1116 GQPGL 1120


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 101/355 (28%), Positives = 121/355 (34%), Gaps = 91/355 (25%)

Query: 396  GPPGPPGGPGMP-----PGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGE 445
            GPPGP G PG+P     PG  GR   +G  GPPG     GE  F++P          G  
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP----------GPP 759

Query: 446  NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG 505
                +    GA       L P GD        RG P       +   + + GP   VGP 
Sbjct: 760  GPPGLPGFKGA-------LGPKGD--------RGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 506  PGGPGPAGPMG------------PFNPGPFNQ----------GPPGAPP-HAGGPPPHQY 542
             G PGP GP G            P  PGP  Q          G PG P     GPP  + 
Sbjct: 805  -GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863

Query: 543  PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPP 602
             P   G   P   P +P  P KA A+                  PPGP PGP   P    
Sbjct: 864  SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG-----PPGP-PGPLGIPGRSG 917

Query: 603  A---------QGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK 653
                      QG+P  P PTG+           K    +P  PG P   D          
Sbjct: 918  VPGLKGDDGLQGQPGLPGPTGE-----------KGSKGEPGLPGPPGPMD-----PNLLG 961

Query: 654  KQAQVATGGGPGAPPGSQP-DYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQ 707
             + +    G PG P  S P  Y     +  +   +     PGP GP+  P   GQ
Sbjct: 962  SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 190/754 (25%), Positives = 243/754 (32%), Gaps = 180/754 (23%)

Query: 11  PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69
           PGPP P G  G  G  G    PG PG  G  G  GP G     G+ G    P   G PG+
Sbjct: 83  PGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142

Query: 70  RKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDS 129
           +       +   +       G+  + + +S P     G K        P  + L      
Sbjct: 143 QGPPGPPGIPGMK-------GEPGSIIMSSLP-----GPKGNPGYPGPPGIQGLPGP-TG 189

Query: 130 ISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPE 189
           I   +GP  PP           P G  GL   +G   +N  Q   G K +      G P 
Sbjct: 190 IPGPIGPPGPPGLMG-------PPGPPGLPGPKGNMGLN-FQGPKGEKGEQGLQ--GPP- 238

Query: 190 RSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVI 249
                 G P  + + K  +D    +G  G PG   D    G  G    I  P G  G   
Sbjct: 239 ------GPPGQISEQKRPIDVEFQKGDQGLPG---DRGPPGPPG----IRGPPGPPGGEK 285

Query: 250 GKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDP-YKVQQACEMVMDILRERDQ 308
           G+ GE     Q   G +    +DG +N     P  + GDP Y  +          R+ ++
Sbjct: 286 GEKGE-----QGEPGKRGKPGKDG-ENGQPGIP-GLPGDPGYPGEPG--------RDGEK 330

Query: 309 GGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEM-IKKIQNDAGVRIQFKQDDGTGPE 367
           G  GD    G        + +PR   G+ IG  G + +  +  + G R            
Sbjct: 331 GQKGDTGPPGPP-----GLVIPRPGTGITIGEKGNIGLPGLPGEKGER------------ 373

Query: 368 KIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPG----GPGMPPGGRGRGRGQGNWGPP 423
               I GPP                   G PGPPG    GP  PPG  G    +G+ GPP
Sbjct: 374 GFPGIQGPP-------------------GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414

Query: 424 GGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSP-- 481
           G     SIP    GL    G   +       G  +  S ++   G P        GSP  
Sbjct: 415 G----ISIPGPP-GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP-----GSPGD 464

Query: 482 -----------QQIDHAKQLIEEKIEGPLCPVGPG-PGGPGPAGPMG-PFNPGPFNQ--- 525
                       + D     I   I GP  P  PG PG PGP G +G P   G   Q   
Sbjct: 465 KGLQGEQGVKGDKGDTCFNCIGTGISGP--PGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 526 -GPPGAPPHAGGPPPHQYP------------PQGWGNTYPQWQPPAPHDPSKAAAAAADP 572
            GP G P   G P    +P            P   G+      P AP  P        D 
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 573 NAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE--PPQPP-------------PTGQSD 617
                          PG +PGP   P     +GE  PP  P             P G   
Sbjct: 583 L--------------PG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627

Query: 618 YTKAWEEYYKKIGQQPQQPGAP-----PQQDYTKAWEEYYK----KQAQVATGGGPGAPP 668
                E+  + +   P QPG P     P Q  T+  +        +   V   G PG P 
Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP- 686

Query: 669 GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPP 702
             QP                 G  PGP GP+  P
Sbjct: 687 -GQPGLPGIPGSKGEPGIPGIG-LPGPPGPKGFP 718



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 102/353 (28%), Positives = 122/353 (34%), Gaps = 75/353 (21%)

Query: 395  SGPPGPPGGPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGEN--- 446
            SGPPG PG PG  PG  G G   G  GPPG     G+     P  + G     G  N   
Sbjct: 1136 SGPPGNPGLPG-EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194

Query: 447  --VKAINQQTG----AFVEISRQLP-PNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPL 499
              +  ++ Q G      +  +  LP P G+P F  F                   ++GP 
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGF-----------------PGVQGPP 1237

Query: 500  CPVG-PGP------GGPGPAGPMG-PFNPGPFNQGPPGAPPHAG-----GPPPHQYPPQG 546
             P G PGP      G PGP GP G P  PGP  +GPPG P + G     G P     P  
Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGLPGP--EGPPGLPGNGGIKGEKGNPGQPGLPGL 1295

Query: 547  WGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE 606
             G    Q  P    +P +        +            + P  VPG A  P   P    
Sbjct: 1296 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA-GPEGEPGLIG 1354

Query: 607  PPQPP----PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGG 662
            PP PP    P+GQS   K  +     I  QP   G P  Q            Q      G
Sbjct: 1355 PPGPPGLPGPSGQSIIIKG-DAGPPGIPGQPGLKGLPGPQG----------PQGLPGPTG 1403

Query: 663  GPGAP-PGSQPDYSAAWAEYYRQQAAYYGQ--------TPGPGGPQPPPTQQG 706
             PG P     P +  A     +      GQ         PGP G Q PP   G
Sbjct: 1404 PPGDPGRNGLPGFDGAGGR--KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 205/819 (25%), Positives = 262/819 (31%), Gaps = 228/819 (27%)

Query: 10  PPGPPPPAGGGGGAGGAGGGP-----------PPGPPGA--------------------G 38
           PPGPP   G  G  G    GP           PPGPPG                     G
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264

Query: 39  DRGGGGPGG-----GGPGG--GSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGD 91
           DRG  GP G     G PGG  G  G   +P   G PG                  K G +
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG------------------KDGEN 306

Query: 92  AATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRV 151
               +     D G+ G+  +  DG++ +       G       G + P P T +T   + 
Sbjct: 307 GQPGIPGLPGDPGYPGEPGR--DGEKGQKGDTGPPGPP-----GLVIPRPGTGITIGEKG 359

Query: 152 PDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDI 211
             G+ GL   +G      IQ   G          G P  +V     P      +      
Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLP--------GPPGAAVMGPPGPPGFPGERGQ---- 407

Query: 212 VSRGRGGPPGQFHDNANG--GQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMIL 269
             +G  GPPG       G  GQ G    +  P G AG  I    E  +            
Sbjct: 408 --KGDEGPPGISIPGPPGLDGQPGA-PGLPGPPGPAGPHIPPSDEICEPGPP-------- 456

Query: 270 IQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR-IGGGIDVP 328
              G   +  DK L                     + +QG  GD+ +     IG GI  P
Sbjct: 457 ---GPPGSPGDKGL---------------------QGEQGVKGDKGDTCFNCIGTGISGP 492

Query: 329 VPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDR--CEHAARII 386
             +  +  + G  G +        G + +  Q   TGP+ +  I G P       +    
Sbjct: 493 PGQPGLPGLPGPPGSL-----GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEP 547

Query: 387 NDLL-------QSLRSGPPGPPGGPGMP-----------PGGRGRGRG---QGNWGPPGG 425
            D+L            G PG PG PG+P           PG +G   G   +G  GPPG 
Sbjct: 548 GDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN 607

Query: 426 EMTFSIPTH----------KCGLVIGRGGENVKAINQQTGAFVEISRQLP-PNGDPNFKL 474
                +P +            G V  +G + V     Q G        +P P GDP  + 
Sbjct: 608 PGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG--------IPGPKGDPG-QT 658

Query: 475 FIIRGSPQQIDHAKQLIEEKIEG-PLCPVGPG-PGGPGPAGPMG------PFNPGPFN-- 524
               G P    +  +  +  + G P  P  PG PG PG  G  G      P  PGP    
Sbjct: 659 ITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFP 718

Query: 525 --QGPPGAPPHAG-----GPP-PHQYP-PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAA 575
              GPPGAP   G     GPP P  +P P+G     P +  P P  P            A
Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG----EPGFALPGPPGPPGLPGF----KGA 770

Query: 576 WAAYYSHYYQQPPGP--------VPGP--------APAPAAPP------AQGEPPQPP-- 611
                   +  PPGP        +PGP         P P  PP       QG PP PP  
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG-PPGPPGI 829

Query: 612 --PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPG 669
             P GQ             I  +   PG PP  D      E  +    +    GP  PPG
Sbjct: 830 PGPIGQPG--------LHGIPGEKGDPG-PPGLDVPGPPGE--RGSPGIPGAPGPIGPPG 878

Query: 670 SQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQG 706
           S      A A  +       G    PGP GP   P + G
Sbjct: 879 SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 176/686 (25%), Positives = 216/686 (31%), Gaps = 172/686 (25%)

Query: 10  PPGPPPPAGGGGGAG--------GAGGGPP-PGPPGAGDRGGGGPGG-----GGPGGGSA 55
           PPGPP   G  G  G        G  G P  PGPPG   +G  GP G     G PG    
Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGI--QGLPGPTGIPGPIGPPGPPGL 202

Query: 56  GGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDG 115
            GP  PPG  GP   K       Q  +    + G              G  G   Q+ + 
Sbjct: 203 MGPPGPPGLPGP---KGNMGLNFQGPKGEKGEQGLQ------------GPPGPPGQISEQ 247

Query: 116 DQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSG 175
            +P   +       +    GP  PP         R P G  G   G  GEQ    ++   
Sbjct: 248 KRPIDVEFQKGDQGLPGDRGPPGPP-------GIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 176 CK--VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNG 233
            K      P   GLP       G P                GR G  GQ  D    G  G
Sbjct: 301 GKDGENGQPGIPGLP-GDPGYPGEP----------------GRDGEKGQKGDTGPPGPPG 343

Query: 234 TVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKV 292
               ++IP    G+ IG+ G          G+  +  + G +    +  P  + G P   
Sbjct: 344 ----LVIPRPGTGITIGEKG--------NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391

Query: 293 QQACEMVMDILRERDQGGFGDRNEYGSRIGG--GID-------VPVPRHSVGVVIGRSGE 343
                       ER Q   GD    G  I G  G+D       +P P    G  I  S E
Sbjct: 392 VMGPPGPPGFPGERGQK--GDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 344 MI-------------KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLL 390
           +              K +Q + GV    K D G             D C +        +
Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGV----KGDKG-------------DTCFNC-------I 485

Query: 391 QSLRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVK 448
            +  SGPPG PG PG+  PPG  G    +G  G  G      +P    G+    G     
Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP----GIPGAPGAPGFP 541

Query: 449 AINQQTGAFVEI------SRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE------ 496
               + G  +          +L   G P   L  + G+P Q D    L   K E      
Sbjct: 542 GSKGEPGDILTFPGMKGDKGELGSPGAPG--LPGLPGTPGQ-DGLPGLPGPKGEPGGITF 598

Query: 497 ----GPLCPVGPG-PGGPGPAGPMGPFN---PGPF----------NQGPPGAPPHAGGP- 537
               GP  P  PG PG PG  GPMGP     PGP           N G PG P   G P 
Sbjct: 599 KGERGP--PGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656

Query: 538 -----PPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGP-- 590
                P     P   G       P  P  P +        +             PPGP  
Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716

Query: 591 ---VPGPAPAPAAPPAQG--EPPQPP 611
              +PGP  AP  P   G   PP PP
Sbjct: 717 FPGIPGPPGAPGTPGRIGLEGPPGPP 742



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 98/353 (27%), Positives = 114/353 (32%), Gaps = 88/353 (24%)

Query: 396  GPPGPPGGPGMPPGGRGRGRGQ-GNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKA 449
            GPPGP G PG+P        GQ G  GPPG     G+M F  P          G      
Sbjct: 1003 GPPGPKGNPGLP--------GQPGLIGPPGLKGTIGDMGFPGPQGV------EGPPGPSG 1048

Query: 450  INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDH-------AKQLIEEKIEGPLCPV 502
            +  Q G+   +  Q    GDP      + G P                I+  +  P  P 
Sbjct: 1049 VPGQPGS-PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG 1107

Query: 503  GPG-------------PGGPGPAGPMG----PFNPG-PFNQGPPGAPPHAG--GPPPHQY 542
             PG             PG PGP GP G    P NPG P   GP G   H G  GPP  + 
Sbjct: 1108 LPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKG 1167

Query: 543  PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPP 602
             P   G   P  Q   P  P        +P        S   Q+  G +PG    P  P 
Sbjct: 1168 KPGQDGIPGPAGQKGEPGQP-----GFGNPGPPGLPGLSG--QKGDGGLPGIPGNPGLPG 1220

Query: 603  AQGEP-------PQPPPTGQSDYTKAWEEYYKKIGQQ--PQQPGAPPQQDYTKAWEEYYK 653
             +GEP        Q PP        A E      G Q  P +PG P              
Sbjct: 1221 PKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLP-------------- 1266

Query: 654  KQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQG 706
                     GP  PPG   +      +    Q    G  PG  G Q PP  QG
Sbjct: 1267 ---------GPEGPPGLPGNGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQG 1309



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 89/340 (26%), Positives = 105/340 (30%), Gaps = 97/340 (28%)

Query: 396  GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447
            GP GPPG PG+P        PG +G     G  GPPG      IP        GR G  V
Sbjct: 872  GPIGPPGSPGLPGKAGASGFPGTKGE---MGMMGPPGPPGPLGIP--------GRSG--V 918

Query: 448  KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP--G 505
              +    G                     ++G P             + GP    G    
Sbjct: 919  PGLKGDDG---------------------LQGQP------------GLPGPTGEKGSKGE 945

Query: 506  PGGPGPAGPMGPFNPGPFNQ-GPPGAP--PHAGGPPPHQYPPQGWGNTYPQWQP--PAPH 560
            PG PGP GPM P   G   + G PG P  P   GP  +Q  P   G      QP  P P 
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 561  DPSKAAAAAADPNAAWAAYYSHYYQQP--PGP-----VPGPAPAPAAPPAQGEPPQPPPT 613
             P         P                 PGP      PGP+  P  P + G P Q    
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 614  GQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAP--PGS- 670
            G    +            +P  PG P               +  V   G PG P  PG+ 
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGI----------KGSVGDPGLPGLPGTPGAK 1115

Query: 671  -QPDYSAAWAEYYRQQAAYYGQTPGPGGPQ---PPPTQQG 706
             QP                +  TPGP GP+    PP   G
Sbjct: 1116 GQPGLPG------------FPGTPGPPGPKGISGPPGNPG 1143



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 95/358 (26%), Positives = 114/358 (31%), Gaps = 72/358 (20%)

Query: 365 GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGP-- 422
           GP  I  + G P            ++ S   GP G PG PG PPG +G     G  GP  
Sbjct: 147 GPPGIPGMKGEP----------GSIIMSSLPGPKGNPGYPG-PPGIQGLPGPTGIPGPIG 195

Query: 423 PGGEMTFSIPTHKCGLVIGRG--GENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS 480
           P G      P    GL   +G  G N +    + G   E   Q PP            G 
Sbjct: 196 PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG---EQGLQGPP------------GP 240

Query: 481 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH 540
           P QI   K+ I+ + +     +    G PGP G  GP  PGP   G  G     G P   
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP--PGP-PGGEKGEKGEQGEPGKR 297

Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA 600
             P +   N  P   P  P DP        D               PPGP     P P  
Sbjct: 298 GKPGKDGENGQP-GIPGLPGDPGYPGEPGRDGEKGQKGDTG-----PPGPPGLVIPRPGT 351

Query: 601 PPAQGE------PPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK- 653
               GE      P  P   G        E  +  I   P  PG P            +  
Sbjct: 352 GITIGEKGNIGLPGLPGEKG--------ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403

Query: 654 KQAQVATGGGPG----APPG--SQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQ 705
           ++ Q    G PG     PPG   QP             A      PGP GP  PP+ +
Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPG------------APGLPGPPGPAGPHIPPSDE 449



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 28/63 (44%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69
            PGPP P G  G  G  G   PPG  G  GD G  GP G     G +G P QP   G PG 
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061

Query: 70   RKD 72
            + D
Sbjct: 1062 KGD 1064



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/76 (43%), Positives = 34/76 (44%), Gaps = 14/76 (18%)

Query: 8    GPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRG-GGGPGGGGPGGGS 54
            GPP     PG P P GGGG  G  G     G PG       AG +G  G PG G PG   
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196

Query: 55   AGGPSQPPGGGG-PGI 69
              G S   G GG PGI
Sbjct: 1197 LPGLSGQKGDGGLPGI 1212



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 30/69 (43%), Positives = 32/69 (46%), Gaps = 7/69 (10%)

Query: 6    TGGPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPS 59
            T GPP      GPP   G  G  G  GGG  PG PG  G++G  G  G     G  G P 
Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 60   QPPGGGGPG 68
            Q PG G PG
Sbjct: 1186 Q-PGFGNPG 1193



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 28/64 (43%), Positives = 30/64 (46%), Gaps = 8/64 (12%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGA------GDRGGGGPGG--GGPGGGSAGGPSQPP 62
            PG P P G  G  G  G   PPGPPG+      G +G  GP G  G PG     GP   P
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLP 1275

Query: 63   GGGG 66
            G GG
Sbjct: 1276 GNGG 1279



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 28/66 (42%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 10   PPGPPPPAGGG--GGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPSQPPGGGG 66
            PPGPP   G    G  G  G   PPG PG  G  G  G  G G   G  G P QP   G 
Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1295

Query: 67   PGIRKD 72
            PG++ D
Sbjct: 1296 PGLKGD 1301



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 11/76 (14%)

Query: 8   GPP----PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
           GPP    PGPP   G  G  G  G   PPG PG   + G     G  G     GP  PPG
Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908

Query: 64  -------GGGPGIRKD 72
                   G PG++ D
Sbjct: 909 PLGIPGRSGVPGLKGD 924



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 70/235 (29%), Positives = 80/235 (34%), Gaps = 56/235 (23%)

Query: 394  RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            R G PGP G PG+P  G  +G  +GN G PG      +P    GL   +G +    +   
Sbjct: 1262 RPGLPGPEGPPGLPGNGGIKGE-KGNPGQPG------LP----GLPGLKGDQGPPGLQGN 1310

Query: 454  TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPL-CPVGPGP-GGPGP 511
             G            GDP   L  + G P             ++GP   P   GP G PG 
Sbjct: 1311 PGR----PGLNGMKGDPG--LPGVPGFP------------GMKGPSGVPGSAGPEGEPGL 1352

Query: 512  AGPMGPFN-PGPFNQ--------GPPGAPPHAG--GPPPHQYPPQGWGNTYPQWQPPAPH 560
             GP GP   PGP  Q        GPPG P   G  G P  Q P    G T P   P    
Sbjct: 1353 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1412

Query: 561  DP--SKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPT 613
             P    A     DP              P  P       P  P     PP PP T
Sbjct: 1413 LPGFDGAGGRKGDPGL------------PGQPGTRGLDGPPGPDGLQGPPGPPGT 1455



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 61/216 (28%), Positives = 78/216 (36%), Gaps = 51/216 (23%)

Query: 504 PG-PGGPGPAGPMGPFN----------PGPFN-QGP------------PGAPPHAGGPPP 539
           PG PG PGP GP GP            PGP   +GP            PG P H G P P
Sbjct: 59  PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP 118

Query: 540 HQYP-----------PQGWGNTYPQWQPPAPHDPS-KAAAAAADPNAAWAAYYSHYYQQP 587
              P           P   G    Q  P  P  P  K    +   ++      +  Y  P
Sbjct: 119 QGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP 178

Query: 588 PG--------PVPGPAPAPAAPPAQGEPPQPP--PTGQSDYTKAWEEYYKKIGQQPQQ-- 635
           PG         +PGP   P  PP    PP PP  P  + +    ++    + G+Q  Q  
Sbjct: 179 PGIQGLPGPTGIPGPI-GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237

Query: 636 PGAPPQ-QDYTKAWEEYYKKQAQVATGG-GPGAPPG 669
           PG P Q  +  +  +  ++K  Q   G  GP  PPG
Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/75 (42%), Positives = 35/75 (46%), Gaps = 17/75 (22%)

Query: 12   GPPPPAGGGGGAG--GAGGGPPPGPPG-AGDRGGGG-------PGGGGPGG-----GSAG 56
            G P PAG  G  G  G G   PPG PG +G +G GG       PG  GP G     G  G
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 57   --GPSQPPGGGGPGI 69
              GP  PPG  GP +
Sbjct: 1233 VQGPPGPPGSPGPAL 1247



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 33/78 (42%), Positives = 36/78 (46%), Gaps = 15/78 (19%)

Query: 8    GPP-----PGPPPPAG--GGGGAGGAGGGP-PPGPPG-AGDRGGGGPGG--GGPG----G 52
            GPP     PGP  P G  G GG  G  G P  PG PG  G +G  GP G  G PG     
Sbjct: 1258 GPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1317

Query: 53   GSAGGPSQPPGGGGPGIR 70
            G  G P  P   G PG++
Sbjct: 1318 GMKGDPGLPGVPGFPGMK 1335



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 28/62 (45%), Positives = 29/62 (46%), Gaps = 4/62 (6%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGG-PGGGGP--GGGSAGGPSQPPGGGG 66
            PG P   G  G  G  G   PPGP G +G  G  G PG  GP  GGG  G P  P   G 
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168

Query: 67   PG 68
            PG
Sbjct: 1169 PG 1170



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 28/71 (39%), Positives = 31/71 (43%), Gaps = 12/71 (16%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGP------PGAGDRGGGG----PGGGGPGG--GSAGGP 58
            PG P P G  G  G  G   PPGP         G++G  G    PG  GP G  G  G P
Sbjct: 931  PGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP 990

Query: 59   SQPPGGGGPGI 69
             QP   G PG+
Sbjct: 991  GQPGLSGQPGL 1001



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 31/73 (42%), Positives = 32/73 (43%), Gaps = 19/73 (26%)

Query: 8   GPPPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGGGGPGG----GGPG-GGSAGGP 58
           GPP  P PP        GA    PPGPPG     G +G  GP G    G PG  G  G P
Sbjct: 380 GPPGLPGPP--------GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431

Query: 59  S--QPPGGGGPGI 69
               PPG  GP I
Sbjct: 432 GLPGPPGPAGPHI 444



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 32/78 (41%), Positives = 33/78 (42%), Gaps = 19/78 (24%)

Query: 8   GPPP----GPPPPAGGGGGAGGAGG-GPP----PGPPGAGDRGG--GGPGGGGPGGG--- 53
           GPP     GPP P G  G  G  G  GPP    PGPPG   + G  G PG  GP G    
Sbjct: 386 GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 54  -----SAGGPSQPPGGGG 66
                   GP  PPG  G
Sbjct: 446 PSDEICEPGPPGPPGSPG 463



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 32/71 (45%), Positives = 33/71 (46%), Gaps = 9/71 (12%)

Query: 8   GPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRG-----GGGPG-GGGPG-GGSAGGP 58
           GPP  GPP P G  G  G AG    PG PG  GD G      G PG  G PG  G  G P
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680

Query: 59  SQPPGGGGPGI 69
             P   G PG+
Sbjct: 681 GDPGLPGQPGL 691



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 31/72 (43%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 3   DYSTGGPP--PGPP--PPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSA 55
           D    G P  PG P  P   G  G  G  G   PGPPG  G  G  GP G  G PG    
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 56  GGPSQPPGGGGP 67
            GP  PPG  GP
Sbjct: 736 EGPPGPPGFPGP 747



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 34/87 (39%), Positives = 35/87 (40%), Gaps = 27/87 (31%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGP----------PPGPPG-------------AGDRG-G 42
           G P P  PP + G  G  GA G P          PPGPPG              GD G  
Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 43  GGPGGGGPGG--GSAGGPSQPPGGGGP 67
           G PG  GP G  GS G P   PG  GP
Sbjct: 929 GQPGLPGPTGEKGSKGEPGL-PGPPGP 954



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 29/65 (44%), Positives = 29/65 (44%), Gaps = 5/65 (7%)

Query: 8    GPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63
            GPP  PG P   G  G  G  G   P GPPG   R G  PG  G GG  G  G P QP  
Sbjct: 1376 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGL-PGFDGAGGRKGDPGLPGQPGT 1434

Query: 64   GGGPG 68
             G  G
Sbjct: 1435 RGLDG 1439



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 27/60 (45%), Positives = 27/60 (45%), Gaps = 12/60 (20%)

Query: 10   PPGPPPPAGGGG-----GAGGAGGGPP-PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
            P GPP   G  G     GAGG  G P  PG PG   RG  GP    PG     GP  PPG
Sbjct: 1401 PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT--RGLDGP----PGPDGLQGPPGPPG 1454



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 27/65 (41%), Positives = 28/65 (43%), Gaps = 10/65 (15%)

Query: 10   PPGPPPPAGGGGGA----GGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63
            PPGPP   G  G +    G AG    PG PG      G PG  GP G  G  G P  P  
Sbjct: 1355 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLK----GLPGPQGPQGLPGPTGPPGDPGR 1410

Query: 64   GGGPG 68
             G PG
Sbjct: 1411 NGLPG 1415



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 29/64 (45%), Positives = 30/64 (46%), Gaps = 15/64 (23%)

Query: 6   TGGPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGG--GSAG--GPS 59
           TG P P GPP P G  G         PPGPPG  G +G  G    GP G  G  G  GP 
Sbjct: 188 TGIPGPIGPPGPPGLMG---------PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP 238

Query: 60  QPPG 63
            PPG
Sbjct: 239 GPPG 242



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 27/63 (42%), Positives = 29/63 (46%), Gaps = 6/63 (9%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQP--PGG 64
            PG P   G  G  G  G    PG PGA  + G  G PG  GP G  G +G P  P  PG 
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE 1147

Query: 65   GGP 67
             GP
Sbjct: 1148 PGP 1150



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 28/62 (45%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGG-PGGGSAGGPSQPPG-GGG 66
            PGP  P G  G  G  G   PPG PG G   G  G PG  G PG     G   PPG  G 
Sbjct: 1254 PGPQGPPGRPGLPGPEG---PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN 1310

Query: 67   PG 68
            PG
Sbjct: 1311 PG 1312



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 45/170 (26%), Positives = 53/170 (31%), Gaps = 64/170 (37%)

Query: 365  GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--PGGRGRGRGQGNWGP 422
            GPE    ++GPP            ++    +GPPG PG PG+   PG +G     G  GP
Sbjct: 1345 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1404

Query: 423  PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQ 482
            PG      +P        G GG                       GDP            
Sbjct: 1405 PGDPGRNGLPGFD-----GAGGR---------------------KGDPGL---------- 1428

Query: 483  QIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFN-QGPPGAP 531
                                   PG PG  G  GP  PGP   QGPPG P
Sbjct: 1429 -----------------------PGQPGTRGLDGP--PGPDGLQGPPGPP 1453



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 31/78 (39%), Positives = 32/78 (41%), Gaps = 17/78 (21%)

Query: 10   PPGPPPPAG------GGGGAGGAGGGP-------PPGPPGAGDRGG--GGPGGGG-PGGG 53
            PPG P P+G      G  G  G  G P       P GP G     G  G PG  G PG  
Sbjct: 1358 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1417

Query: 54   SAGGPSQPPG-GGGPGIR 70
             AGG    PG  G PG R
Sbjct: 1418 GAGGRKGDPGLPGQPGTR 1435



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 23/58 (39%), Positives = 23/58 (39%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGP 67
            P GP    G  G  G  G    PG  GAG R G     G PG     GP  P G  GP
Sbjct: 1392 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGP 1449



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 31/79 (39%), Positives = 31/79 (39%), Gaps = 18/79 (22%)

Query: 3   DYSTGGPPP--GPPPPAGGGGGAGGAGGGP-------------PPGPPGA-GDRG-GGGP 45
           D    GPP   GPP P GG  G  G  G P              PG PG  GD G  G P
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324

Query: 46  GGGGPGGGSAG-GPSQPPG 63
           G  G  G     GP  PPG
Sbjct: 325 GRDGEKGQKGDTGPPGPPG 343



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 11/71 (15%)

Query: 8   GPP--PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGG-PGGGGPGGGSAGG 57
           GPP  PG P   G  G  G  G G PPGP G       AG+ G  G PG  G  G +   
Sbjct: 603 GPPGNPGLPGLPGNIGPMGPPGFG-PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661

Query: 58  PSQPPGGGGPG 68
           P +P   G PG
Sbjct: 662 PGKPGLPGNPG 672



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 6/65 (9%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGA----GDRGGGGPGGGGPGG--GSAGGPSQPPGGG 65
            G P P G  G  G +G    PG PG     GD+G  G    G  G  G  G P  P   G
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092

Query: 66   GPGIR 70
             PGI+
Sbjct: 1093 NPGIK 1097



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 29/78 (37%), Positives = 32/78 (41%), Gaps = 18/78 (23%)

Query: 11   PGPPPPAGGG--GGAGGAGGGPPPGPPGA----------GDRG----GGGPGGGGPGG-- 52
            PGPP P      G  G  G    PG PG           GD G     G PG  GP G  
Sbjct: 949  PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008

Query: 53   GSAGGPSQPPGGGGPGIR 70
            G+ G P QP   G PG++
Sbjct: 1009 GNPGLPGQPGLIGPPGLK 1026



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 27/64 (42%), Positives = 29/64 (45%), Gaps = 6/64 (9%)

Query: 11   PGPP--PPAGGGGGAGGAGGGPP-PGPPGAGDRGG--GGPG-GGGPGGGSAGGPSQPPGG 64
            PGPP  P   G  G GG  G P  PG PG     G  G PG  G PG   + GP+     
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 65   GGPG 68
            G PG
Sbjct: 1252 GNPG 1255



 Score = 33.5 bits (75), Expect = 0.70
 Identities = 34/89 (38%), Positives = 35/89 (39%), Gaps = 28/89 (31%)

Query: 8   GPP--------PGPPPPAG--------GGGGAGGAGGGPP-PGPPGA----GDRGGGG-- 44
           GPP        PGPP   G        G  GA G  G P  PG PGA    G +G  G  
Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI 550

Query: 45  ---PGGGGPGG--GSAGGPSQPPGGGGPG 68
              PG  G  G  GS G P  P   G PG
Sbjct: 551 LTFPGMKGDKGELGSPGAPGLPGLPGTPG 579



 Score = 33.5 bits (75), Expect = 0.70
 Identities = 25/66 (37%), Positives = 27/66 (40%), Gaps = 6/66 (9%)

Query: 10   PPGPPPPAGGGGGAGGAG-GGPP-----PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
            PPG     G  G  G  G  GPP     PG PG+    G     G PG  S G P  P  
Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081

Query: 64   GGGPGI 69
             G PG+
Sbjct: 1082 KGEPGL 1087



 Score = 33.1 bits (74), Expect = 0.92
 Identities = 28/81 (34%), Positives = 31/81 (38%), Gaps = 21/81 (25%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGG------PGGGGPGG----------- 52
            PGP    G  G +G  G    PG PG  GD+G  G      PG  GP G           
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094

Query: 53   ---GSAGGPSQPPGGGGPGIR 70
               GS G P  P   G PG +
Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAK 1115



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 21/58 (36%), Positives = 21/58 (36%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGP 67
            P G P   G  G  G  G    PG PG     G     G PG     GP  P G  GP
Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 12/72 (16%)

Query: 10  PPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGG-GGPGGGGPGG-------GSAGG 57
           PPGP    G  G  G  G     G PG     G++G  G PG  GP G       GS G 
Sbjct: 906 PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965

Query: 58  PSQPPGGGGPGI 69
             +P   G PG+
Sbjct: 966 KGEPGLPGIPGV 977



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 6/65 (9%)

Query: 11   PGPPPPAGGGGGAGGAGGGPP--PGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGG 64
            PG P   G  G  G +  G P  PGP G     G  G PG  G  G  G  G P  P   
Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115

Query: 65   GGPGI 69
            G PG+
Sbjct: 1116 GQPGL 1120


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 101/355 (28%), Positives = 121/355 (34%), Gaps = 91/355 (25%)

Query: 396  GPPGPPGGPGMP-----PGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGE 445
            GPPGP G PG+P     PG  GR   +G  GPPG     GE  F++P          G  
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP----------GPP 759

Query: 446  NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGPG 505
                +    GA       L P GD        RG P       +   + + GP   VGP 
Sbjct: 760  GPPGLPGFKGA-------LGPKGD--------RGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 506  PGGPGPAGPMG------------PFNPGPFNQ----------GPPGAPP-HAGGPPPHQY 542
             G PGP GP G            P  PGP  Q          G PG P     GPP  + 
Sbjct: 805  -GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863

Query: 543  PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPP 602
             P   G   P   P +P  P KA A+                  PPGP PGP   P    
Sbjct: 864  SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG-----PPGP-PGPLGIPGRSG 917

Query: 603  A---------QGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK 653
                      QG+P  P PTG+           K    +P  PG P   D          
Sbjct: 918  VPGLKGDDGLQGQPGLPGPTGE-----------KGSKGEPGLPGPPGPMD-----PNLLG 961

Query: 654  KQAQVATGGGPGAPPGSQP-DYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQ 707
             + +    G PG P  S P  Y     +  +   +     PGP GP+  P   GQ
Sbjct: 962  SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 190/754 (25%), Positives = 243/754 (32%), Gaps = 180/754 (23%)

Query: 11  PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69
           PGPP P G  G  G  G    PG PG  G  G  GP G     G+ G    P   G PG+
Sbjct: 83  PGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142

Query: 70  RKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDS 129
           +       +   +       G+  + + +S P     G K        P  + L      
Sbjct: 143 QGPPGPPGIPGMK-------GEPGSIIMSSLP-----GPKGNPGYPGPPGIQGLPGP-TG 189

Query: 130 ISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPE 189
           I   +GP  PP           P G  GL   +G   +N  Q   G K +      G P 
Sbjct: 190 IPGPIGPPGPPGLMG-------PPGPPGLPGPKGNMGLN-FQGPKGEKGEQGLQ--GPP- 238

Query: 190 RSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVI 249
                 G P  + + K  +D    +G  G PG   D    G  G    I  P G  G   
Sbjct: 239 ------GPPGQISEQKRPIDVEFQKGDQGLPG---DRGPPGPPG----IRGPPGPPGGEK 285

Query: 250 GKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDP-YKVQQACEMVMDILRERDQ 308
           G+ GE     Q   G +    +DG +N     P  + GDP Y  +          R+ ++
Sbjct: 286 GEKGE-----QGEPGKRGKPGKDG-ENGQPGIP-GLPGDPGYPGEPG--------RDGEK 330

Query: 309 GGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEM-IKKIQNDAGVRIQFKQDDGTGPE 367
           G  GD    G        + +PR   G+ IG  G + +  +  + G R            
Sbjct: 331 GQKGDTGPPGPP-----GLVIPRPGTGITIGEKGNIGLPGLPGEKGER------------ 373

Query: 368 KIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPG----GPGMPPGGRGRGRGQGNWGPP 423
               I GPP                   G PGPPG    GP  PPG  G    +G+ GPP
Sbjct: 374 GFPGIQGPP-------------------GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414

Query: 424 GGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSP-- 481
           G     SIP    GL    G   +       G  +  S ++   G P        GSP  
Sbjct: 415 G----ISIPGPP-GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP-----GSPGD 464

Query: 482 -----------QQIDHAKQLIEEKIEGPLCPVGPG-PGGPGPAGPMG-PFNPGPFNQ--- 525
                       + D     I   I GP  P  PG PG PGP G +G P   G   Q   
Sbjct: 465 KGLQGEQGVKGDKGDTCFNCIGTGISGP--PGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 526 -GPPGAPPHAGGPPPHQYP------------PQGWGNTYPQWQPPAPHDPSKAAAAAADP 572
            GP G P   G P    +P            P   G+      P AP  P        D 
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 573 NAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGE--PPQPP-------------PTGQSD 617
                          PG +PGP   P     +GE  PP  P             P G   
Sbjct: 583 L--------------PG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627

Query: 618 YTKAWEEYYKKIGQQPQQPGAP-----PQQDYTKAWEEYYK----KQAQVATGGGPGAPP 668
                E+  + +   P QPG P     P Q  T+  +        +   V   G PG P 
Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP- 686

Query: 669 GSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPP 702
             QP                 G  PGP GP+  P
Sbjct: 687 -GQPGLPGIPGSKGEPGIPGIG-LPGPPGPKGFP 718



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 205/819 (25%), Positives = 262/819 (31%), Gaps = 228/819 (27%)

Query: 10  PPGPPPPAGGGGGAGGAGGGP-----------PPGPPGA--------------------G 38
           PPGPP   G  G  G    GP           PPGPPG                     G
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264

Query: 39  DRGGGGPGG-----GGPGG--GSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGD 91
           DRG  GP G     G PGG  G  G   +P   G PG                  K G +
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG------------------KDGEN 306

Query: 92  AATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRV 151
               +     D G+ G+  +  DG++ +       G       G + P P T +T   + 
Sbjct: 307 GQPGIPGLPGDPGYPGEPGR--DGEKGQKGDTGPPGPP-----GLVIPRPGTGITIGEKG 359

Query: 152 PDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDI 211
             G+ GL   +G      IQ   G          G P  +V     P      +      
Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLP--------GPPGAAVMGPPGPPGFPGERGQ---- 407

Query: 212 VSRGRGGPPGQFHDNANG--GQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMIL 269
             +G  GPPG       G  GQ G    +  P G AG  I    E  +            
Sbjct: 408 --KGDEGPPGISIPGPPGLDGQPGA-PGLPGPPGPAGPHIPPSDEICEPGPP-------- 456

Query: 270 IQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR-IGGGIDVP 328
              G   +  DK L                     + +QG  GD+ +     IG GI  P
Sbjct: 457 ---GPPGSPGDKGL---------------------QGEQGVKGDKGDTCFNCIGTGISGP 492

Query: 329 VPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDR--CEHAARII 386
             +  +  + G  G +        G + +  Q   TGP+ +  I G P       +    
Sbjct: 493 PGQPGLPGLPGPPGSL-----GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEP 547

Query: 387 NDLL-------QSLRSGPPGPPGGPGMP-----------PGGRGRGRG---QGNWGPPGG 425
            D+L            G PG PG PG+P           PG +G   G   +G  GPPG 
Sbjct: 548 GDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN 607

Query: 426 EMTFSIPTH----------KCGLVIGRGGENVKAINQQTGAFVEISRQLP-PNGDPNFKL 474
                +P +            G V  +G + V     Q G        +P P GDP  + 
Sbjct: 608 PGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG--------IPGPKGDPG-QT 658

Query: 475 FIIRGSPQQIDHAKQLIEEKIEG-PLCPVGPG-PGGPGPAGPMG------PFNPGPFN-- 524
               G P    +  +  +  + G P  P  PG PG PG  G  G      P  PGP    
Sbjct: 659 ITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFP 718

Query: 525 --QGPPGAPPHAG-----GPP-PHQYP-PQGWGNTYPQWQPPAPHDPSKAAAAAADPNAA 575
              GPPGAP   G     GPP P  +P P+G     P +  P P  P            A
Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG----EPGFALPGPPGPPGLPGF----KGA 770

Query: 576 WAAYYSHYYQQPPGP--------VPGP--------APAPAAPP------AQGEPPQPP-- 611
                   +  PPGP        +PGP         P P  PP       QG PP PP  
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG-PPGPPGI 829

Query: 612 --PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPG 669
             P GQ             I  +   PG PP  D      E  +    +    GP  PPG
Sbjct: 830 PGPIGQPG--------LHGIPGEKGDPG-PPGLDVPGPPGE--RGSPGIPGAPGPIGPPG 878

Query: 670 SQPDYSAAWAEYYRQQAAYYGQ--TPGPGGPQPPPTQQG 706
           S      A A  +       G    PGP GP   P + G
Sbjct: 879 SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 176/686 (25%), Positives = 216/686 (31%), Gaps = 172/686 (25%)

Query: 10  PPGPPPPAGGGGGAG--------GAGGGPP-PGPPGAGDRGGGGPGG-----GGPGGGSA 55
           PPGPP   G  G  G        G  G P  PGPPG   +G  GP G     G PG    
Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGI--QGLPGPTGIPGPIGPPGPPGL 202

Query: 56  GGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDG 115
            GP  PPG  GP   K       Q  +    + G              G  G   Q+ + 
Sbjct: 203 MGPPGPPGLPGP---KGNMGLNFQGPKGEKGEQGLQ------------GPPGPPGQISEQ 247

Query: 116 DQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSG 175
            +P   +       +    GP  PP         R P G  G   G  GEQ    ++   
Sbjct: 248 KRPIDVEFQKGDQGLPGDRGPPGPP-------GIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 176 CK--VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNG 233
            K      P   GLP       G P                GR G  GQ  D    G  G
Sbjct: 301 GKDGENGQPGIPGLP-GDPGYPGEP----------------GRDGEKGQKGDTGPPGPPG 343

Query: 234 TVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQN-TNVDKPLRIIGDPYKV 292
               ++IP    G+ IG+ G          G+  +  + G +    +  P  + G P   
Sbjct: 344 ----LVIPRPGTGITIGEKG--------NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391

Query: 293 QQACEMVMDILRERDQGGFGDRNEYGSRIGG--GID-------VPVPRHSVGVVIGRSGE 343
                       ER Q   GD    G  I G  G+D       +P P    G  I  S E
Sbjct: 392 VMGPPGPPGFPGERGQK--GDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 344 MI-------------KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLL 390
           +              K +Q + GV    K D G             D C +        +
Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGV----KGDKG-------------DTCFNC-------I 485

Query: 391 QSLRSGPPGPPGGPGM--PPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVK 448
            +  SGPPG PG PG+  PPG  G    +G  G  G      +P    G+    G     
Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP----GIPGAPGAPGFP 541

Query: 449 AINQQTGAFVEI------SRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE------ 496
               + G  +          +L   G P   L  + G+P Q D    L   K E      
Sbjct: 542 GSKGEPGDILTFPGMKGDKGELGSPGAPG--LPGLPGTPGQ-DGLPGLPGPKGEPGGITF 598

Query: 497 ----GPLCPVGPG-PGGPGPAGPMGPFN---PGPF----------NQGPPGAPPHAGGP- 537
               GP  P  PG PG PG  GPMGP     PGP           N G PG P   G P 
Sbjct: 599 KGERGP--PGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656

Query: 538 -----PPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGP-- 590
                P     P   G       P  P  P +        +             PPGP  
Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG 716

Query: 591 ---VPGPAPAPAAPPAQG--EPPQPP 611
              +PGP  AP  P   G   PP PP
Sbjct: 717 FPGIPGPPGAPGTPGRIGLEGPPGPP 742



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 100/354 (28%), Positives = 120/354 (33%), Gaps = 74/354 (20%)

Query: 395  SGPPGPPGGPGMPPGGRGRGRGQGNWGPPG-----GEMTFSIPTHKCGLVIGRGGEN--- 446
            SGPPG PG PG  PG  G G   G  GPPG     G+     P  + G     G  N   
Sbjct: 1136 SGPPGNPGLPG-EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194

Query: 447  --VKAINQQTG----AFVEISRQLP-PNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPL 499
              +  ++ Q G      +  +  LP P G+P F  F                   ++GP 
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGF-----------------PGVQGPP 1237

Query: 500  CPVG-PGP------GGPGPAGPMG--PFNPGPFNQGPPGAPPHAG-----GPPPHQYPPQ 545
             P G PGP      G PGP GP G   F   P  +GPPG P + G     G P     P 
Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPG 1297

Query: 546  GWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQG 605
              G    Q  P    +P +        +            + P  VPG A  P   P   
Sbjct: 1298 LPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA-GPEGEPGLI 1356

Query: 606  EPPQPP----PTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATG 661
             PP PP    P+GQS   K  +     I  QP   G P  Q            Q      
Sbjct: 1357 GPPGPPGLPGPSGQSIIIKG-DAGPPGIPGQPGLKGLPGPQG----------PQGLPGPT 1405

Query: 662  GGPGAP-PGSQPDYSAAWAEYYRQQAAYYGQ--------TPGPGGPQPPPTQQG 706
            G PG P     P +  A     +      GQ         PGP G Q PP   G
Sbjct: 1406 GPPGDPGRNGLPGFDGAGGR--KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 98/351 (27%), Positives = 113/351 (32%), Gaps = 81/351 (23%)

Query: 396  GPPGPPGGPGMPPGGRGRGRGQ-GNWGPPG-----GEMTFSIPTHKCGLVIGRGGENVKA 449
            GPPGP G PG+P        GQ G  GPPG     G+M F  P          G      
Sbjct: 1003 GPPGPKGNPGLP--------GQPGLIGPPGLKGTIGDMGFPGPQGV------EGPPGPSG 1048

Query: 450  INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDH-------AKQLIEEKIEGPLCPV 502
            +  Q G+   +  Q    GDP      + G P                I+  +  P  P 
Sbjct: 1049 VPGQPGS-PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG 1107

Query: 503  GPG-------------PGGPGPAGPMG----PFNPG-PFNQGPPGAPPHAG--GPPPHQY 542
             PG             PG PGP GP G    P NPG P   GP G   H G  GPP  + 
Sbjct: 1108 LPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKG 1167

Query: 543  PPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPP 602
             P   G   P  Q   P  P        +P        S   Q+  G +PG    P  P 
Sbjct: 1168 KPGQDGIPGPAGQKGEPGQP-----GFGNPGPPGLPGLSG--QKGDGGLPGIPGNPGLPG 1220

Query: 603  AQGEP-------PQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQ 655
             +GEP        Q PP        A E      G Q   PG P  Q             
Sbjct: 1221 PKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ-GPPGRPGFQGLP---------- 1269

Query: 656  AQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQG 706
                   GP  PPG   +      +    Q    G  PG  G Q PP  QG
Sbjct: 1270 -------GPEGPPGLPGNGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQG 1312



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 89/340 (26%), Positives = 105/340 (30%), Gaps = 97/340 (28%)

Query: 396  GPPGPPGGPGMP--------PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENV 447
            GP GPPG PG+P        PG +G     G  GPPG      IP        GR G  V
Sbjct: 872  GPIGPPGSPGLPGKAGASGFPGTKGE---MGMMGPPGPPGPLGIP--------GRSG--V 918

Query: 448  KAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVGP--G 505
              +    G                     ++G P             + GP    G    
Sbjct: 919  PGLKGDDG---------------------LQGQP------------GLPGPTGEKGSKGE 945

Query: 506  PGGPGPAGPMGPFNPGPFNQ-GPPGAP--PHAGGPPPHQYPPQGWGNTYPQWQP--PAPH 560
            PG PGP GPM P   G   + G PG P  P   GP  +Q  P   G      QP  P P 
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 561  DPSKAAAAAADPNAAWAAYYSHYYQQP--PGP-----VPGPAPAPAAPPAQGEPPQPPPT 613
             P         P                 PGP      PGP+  P  P + G P Q    
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 614  GQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAP--PGS- 670
            G    +            +P  PG P               +  V   G PG P  PG+ 
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGI----------KGSVGDPGLPGLPGTPGAK 1115

Query: 671  -QPDYSAAWAEYYRQQAAYYGQTPGPGGPQ---PPPTQQG 706
             QP                +  TPGP GP+    PP   G
Sbjct: 1116 GQPGLPG------------FPGTPGPPGPKGISGPPGNPG 1143



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 95/358 (26%), Positives = 114/358 (31%), Gaps = 72/358 (20%)

Query: 365 GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGP-- 422
           GP  I  + G P            ++ S   GP G PG PG PPG +G     G  GP  
Sbjct: 147 GPPGIPGMKGEP----------GSIIMSSLPGPKGNPGYPG-PPGIQGLPGPTGIPGPIG 195

Query: 423 PGGEMTFSIPTHKCGLVIGRG--GENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS 480
           P G      P    GL   +G  G N +    + G   E   Q PP            G 
Sbjct: 196 PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG---EQGLQGPP------------GP 240

Query: 481 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH 540
           P QI   K+ I+ + +     +    G PGP G  GP  PGP   G  G     G P   
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP--PGP-PGGEKGEKGEQGEPGKR 297

Query: 541 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA 600
             P +   N  P   P  P DP        D               PPGP     P P  
Sbjct: 298 GKPGKDGENGQP-GIPGLPGDPGYPGEPGRDGEKGQKGDTG-----PPGPPGLVIPRPGT 351

Query: 601 PPAQGE------PPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK- 653
               GE      P  P   G        E  +  I   P  PG P            +  
Sbjct: 352 GITIGEKGNIGLPGLPGEKG--------ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPG 403

Query: 654 KQAQVATGGGPG----APPG--SQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQ 705
           ++ Q    G PG     PPG   QP             A      PGP GP  PP+ +
Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPG------------APGLPGPPGPAGPHIPPSDE 449



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 29/66 (43%), Positives = 31/66 (46%), Gaps = 8/66 (12%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGA------GDRGGGGPGG--GGPGGGSAGGPSQPP 62
            PG P P G  G  G  G   PPGPPG+      G +G  GP G  G PG     GP  PP
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPP 1275

Query: 63   GGGGPG 68
            G  G G
Sbjct: 1276 GLPGNG 1281



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 28/63 (44%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGI 69
            PGPP P G  G  G  G   PPG  G  GD G  GP G     G +G P QP   G PG 
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061

Query: 70   RKD 72
            + D
Sbjct: 1062 KGD 1064



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/76 (43%), Positives = 34/76 (44%), Gaps = 14/76 (18%)

Query: 8    GPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRG-GGGPGGGGPGGGS 54
            GPP     PG P P GGGG  G  G     G PG       AG +G  G PG G PG   
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196

Query: 55   AGGPSQPPGGGG-PGI 69
              G S   G GG PGI
Sbjct: 1197 LPGLSGQKGDGGLPGI 1212



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 30/69 (43%), Positives = 32/69 (46%), Gaps = 7/69 (10%)

Query: 6    TGGPP-----PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGGGSAGGPS 59
            T GPP      GPP   G  G  G  GGG  PG PG  G++G  G  G     G  G P 
Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 60   QPPGGGGPG 68
            Q PG G PG
Sbjct: 1186 Q-PGFGNPG 1193



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 30/69 (43%), Positives = 32/69 (46%), Gaps = 6/69 (8%)

Query: 10   PPGPPPPAGGG--GGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPG 63
            PPGPP   G    G  G  G   PPG PG     G  G PG  G GG  G  G P QP  
Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1295

Query: 64   GGGPGIRKD 72
             G PG++ D
Sbjct: 1296 PGLPGLKGD 1304



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 11/76 (14%)

Query: 8   GPP----PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
           GPP    PGPP   G  G  G  G   PPG PG   + G     G  G     GP  PPG
Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908

Query: 64  -------GGGPGIRKD 72
                   G PG++ D
Sbjct: 909 PLGIPGRSGVPGLKGD 924



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 61/216 (28%), Positives = 78/216 (36%), Gaps = 51/216 (23%)

Query: 504 PG-PGGPGPAGPMGPFN----------PGPFN-QGP------------PGAPPHAGGPPP 539
           PG PG PGP GP GP            PGP   +GP            PG P H G P P
Sbjct: 59  PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP 118

Query: 540 HQYP-----------PQGWGNTYPQWQPPAPHDPS-KAAAAAADPNAAWAAYYSHYYQQP 587
              P           P   G    Q  P  P  P  K    +   ++      +  Y  P
Sbjct: 119 QGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP 178

Query: 588 PG--------PVPGPAPAPAAPPAQGEPPQPP--PTGQSDYTKAWEEYYKKIGQQPQQ-- 635
           PG         +PGP   P  PP    PP PP  P  + +    ++    + G+Q  Q  
Sbjct: 179 PGIQGLPGPTGIPGPI-GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237

Query: 636 PGAPPQ-QDYTKAWEEYYKKQAQVATGG-GPGAPPG 669
           PG P Q  +  +  +  ++K  Q   G  GP  PPG
Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/75 (42%), Positives = 35/75 (46%), Gaps = 17/75 (22%)

Query: 12   GPPPPAGGGGGAG--GAGGGPPPGPPG-AGDRGGGG-------PGGGGPGG-----GSAG 56
            G P PAG  G  G  G G   PPG PG +G +G GG       PG  GP G     G  G
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 57   --GPSQPPGGGGPGI 69
              GP  PPG  GP +
Sbjct: 1233 VQGPPGPPGSPGPAL 1247



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 67/244 (27%), Positives = 76/244 (31%), Gaps = 46/244 (18%)

Query: 396  GPPGPPGGPGMPPGGRGRGRGQGNWGPPG--GEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            GPPGPPG PG  P   G     G  GPPG  G      P    GL  G GG   +  N  
Sbjct: 1235 GPPGPPGSPG--PALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLP-GNGGIKGEKGNPG 1291

Query: 454  TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEG-PLCPVGPGPGG---- 508
                  +       G P      ++G+P +        +  + G P  P   GP G    
Sbjct: 1292 QPGLPGLPGLKGDQGPPG-----LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1346

Query: 509  ------------PGPAGPMGPFNPGPF---NQGPPGAPPHAG--GPPPHQYPPQGWGNTY 551
                        PGP G  GP         + GPPG P   G  G P  Q P    G T 
Sbjct: 1347 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1406

Query: 552  PQWQPPAPHDP--SKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQ 609
            P   P     P    A     DP              P  P       P  P     PP 
Sbjct: 1407 PPGDPGRNGLPGFDGAGGRKGDPGL------------PGQPGTRGLDGPPGPDGLQGPPG 1454

Query: 610  PPPT 613
            PP T
Sbjct: 1455 PPGT 1458



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 28/62 (45%), Positives = 29/62 (46%), Gaps = 4/62 (6%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGG-PGGGGP--GGGSAGGPSQPPGGGG 66
            PG P   G  G  G  G   PPGP G +G  G  G PG  GP  GGG  G P  P   G 
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168

Query: 67   PG 68
            PG
Sbjct: 1169 PG 1170



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 28/68 (41%), Positives = 31/68 (45%), Gaps = 7/68 (10%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPG----GGSAGGPSQPP 62
            P GPP   G GG  G  G    PG PG  G +G  GP G  G PG     G  G P  P 
Sbjct: 1271 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1330

Query: 63   GGGGPGIR 70
              G PG++
Sbjct: 1331 VPGFPGMK 1338



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 28/71 (39%), Positives = 31/71 (43%), Gaps = 12/71 (16%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGP------PGAGDRGGGG----PGGGGPGG--GSAGGP 58
            PG P P G  G  G  G   PPGP         G++G  G    PG  GP G  G  G P
Sbjct: 931  PGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP 990

Query: 59   SQPPGGGGPGI 69
             QP   G PG+
Sbjct: 991  GQPGLSGQPGL 1001



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 31/73 (42%), Positives = 32/73 (43%), Gaps = 19/73 (26%)

Query: 8   GPPPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGGGGPGG----GGPG-GGSAGGP 58
           GPP  P PP        GA    PPGPPG     G +G  GP G    G PG  G  G P
Sbjct: 380 GPPGLPGPP--------GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431

Query: 59  S--QPPGGGGPGI 69
               PPG  GP I
Sbjct: 432 GLPGPPGPAGPHI 444



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 32/78 (41%), Positives = 33/78 (42%), Gaps = 19/78 (24%)

Query: 8   GPPP----GPPPPAGGGGGAGGAGG-GPP----PGPPGAGDRGG--GGPGGGGPGGG--- 53
           GPP     GPP P G  G  G  G  GPP    PGPPG   + G  G PG  GP G    
Sbjct: 386 GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 54  -----SAGGPSQPPGGGG 66
                   GP  PPG  G
Sbjct: 446 PSDEICEPGPPGPPGSPG 463



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 32/71 (45%), Positives = 33/71 (46%), Gaps = 9/71 (12%)

Query: 8   GPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRG-----GGGPG-GGGPG-GGSAGGP 58
           GPP  GPP P G  G  G AG    PG PG  GD G      G PG  G PG  G  G P
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP 680

Query: 59  SQPPGGGGPGI 69
             P   G PG+
Sbjct: 681 GDPGLPGQPGL 691



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 31/72 (43%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 3   DYSTGGPP--PGPP--PPAGGGGGAGGAGGGPPPGPPGA-GDRGGGGPGG--GGPGGGSA 55
           D    G P  PG P  P   G  G  G  G   PGPPG  G  G  GP G  G PG    
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 56  GGPSQPPGGGGP 67
            GP  PPG  GP
Sbjct: 736 EGPPGPPGFPGP 747



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 34/87 (39%), Positives = 35/87 (40%), Gaps = 27/87 (31%)

Query: 7   GGPPPGPPPPAGGGGGAGGAGGGP----------PPGPPG-------------AGDRG-G 42
           G P P  PP + G  G  GA G P          PPGPPG              GD G  
Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 43  GGPGGGGPGG--GSAGGPSQPPGGGGP 67
           G PG  GP G  GS G P   PG  GP
Sbjct: 929 GQPGLPGPTGEKGSKGEPGL-PGPPGP 954



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 29/65 (44%), Positives = 29/65 (44%), Gaps = 5/65 (7%)

Query: 8    GPP--PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63
            GPP  PG P   G  G  G  G   P GPPG   R G  PG  G GG  G  G P QP  
Sbjct: 1379 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGL-PGFDGAGGRKGDPGLPGQPGT 1437

Query: 64   GGGPG 68
             G  G
Sbjct: 1438 RGLDG 1442



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 27/60 (45%), Positives = 27/60 (45%), Gaps = 12/60 (20%)

Query: 10   PPGPPPPAGGGG-----GAGGAGGGPP-PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
            P GPP   G  G     GAGG  G P  PG PG   RG  GP    PG     GP  PPG
Sbjct: 1404 PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT--RGLDGP----PGPDGLQGPPGPPG 1457



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 27/65 (41%), Positives = 28/65 (43%), Gaps = 10/65 (15%)

Query: 10   PPGPPPPAGGGGGA----GGAGGGPPPGPPGAGDRGGGGPGGGGPGG--GSAGGPSQPPG 63
            PPGPP   G  G +    G AG    PG PG      G PG  GP G  G  G P  P  
Sbjct: 1358 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLK----GLPGPQGPQGLPGPTGPPGDPGR 1413

Query: 64   GGGPG 68
             G PG
Sbjct: 1414 NGLPG 1418



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 29/64 (45%), Positives = 30/64 (46%), Gaps = 15/64 (23%)

Query: 6   TGGPPP-GPPPPAGGGGGAGGAGGGPPPGPPG-AGDRGGGGPGGGGPGG--GSAG--GPS 59
           TG P P GPP P G  G         PPGPPG  G +G  G    GP G  G  G  GP 
Sbjct: 188 TGIPGPIGPPGPPGLMG---------PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP 238

Query: 60  QPPG 63
            PPG
Sbjct: 239 GPPG 242



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 27/63 (42%), Positives = 29/63 (46%), Gaps = 6/63 (9%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQP--PGG 64
            PG P   G  G  G  G    PG PGA  + G  G PG  GP G  G +G P  P  PG 
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE 1147

Query: 65   GGP 67
             GP
Sbjct: 1148 PGP 1150



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 45/170 (26%), Positives = 53/170 (31%), Gaps = 64/170 (37%)

Query: 365  GPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--PGGRGRGRGQGNWGP 422
            GPE    ++GPP            ++    +GPPG PG PG+   PG +G     G  GP
Sbjct: 1348 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1407

Query: 423  PGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQ 482
            PG      +P        G GG                       GDP            
Sbjct: 1408 PGDPGRNGLPGFD-----GAGGR---------------------KGDPGL---------- 1431

Query: 483  QIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFN-QGPPGAP 531
                                   PG PG  G  GP  PGP   QGPPG P
Sbjct: 1432 -----------------------PGQPGTRGLDGP--PGPDGLQGPPGPP 1456



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 29/67 (43%), Positives = 29/67 (43%), Gaps = 6/67 (8%)

Query: 8    GPPPGPPP--PAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPGGGG-PGGGSAGGPSQPP 62
            GP   P P  P G  G  G  G   PPG PG G   G  G PG  G PG     G   PP
Sbjct: 1249 GPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1308

Query: 63   G-GGGPG 68
            G  G PG
Sbjct: 1309 GLQGNPG 1315



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 31/78 (39%), Positives = 32/78 (41%), Gaps = 17/78 (21%)

Query: 10   PPGPPPPAG------GGGGAGGAGGGP-------PPGPPGAGDRGG--GGPGGGG-PGGG 53
            PPG P P+G      G  G  G  G P       P GP G     G  G PG  G PG  
Sbjct: 1361 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1420

Query: 54   SAGGPSQPPG-GGGPGIR 70
             AGG    PG  G PG R
Sbjct: 1421 GAGGRKGDPGLPGQPGTR 1438



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 25/60 (41%), Positives = 25/60 (41%), Gaps = 3/60 (5%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGG--GGPG-GGGPGGGSAGGPSQPPGGGGP 67
            PGP  P G  G  G  G     G PG    GG  G PG  G PG     GP  P G  GP
Sbjct: 1393 PGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGP 1452



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 31/79 (39%), Positives = 31/79 (39%), Gaps = 18/79 (22%)

Query: 3   DYSTGGPPP--GPPPPAGGGGGAGGAGGGP-------------PPGPPGA-GDRG-GGGP 45
           D    GPP   GPP P GG  G  G  G P              PG PG  GD G  G P
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324

Query: 46  GGGGPGGGSAG-GPSQPPG 63
           G  G  G     GP  PPG
Sbjct: 325 GRDGEKGQKGDTGPPGPPG 343



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 11/71 (15%)

Query: 8   GPP--PGPPPPAGGGGGAGGAGGGPPPGPPG-------AGDRGGGG-PGGGGPGGGSAGG 57
           GPP  PG P   G  G  G  G G PPGP G       AG+ G  G PG  G  G +   
Sbjct: 603 GPPGNPGLPGLPGNIGPMGPPGFG-PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661

Query: 58  PSQPPGGGGPG 68
           P +P   G PG
Sbjct: 662 PGKPGLPGNPG 672



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 6/65 (9%)

Query: 12   GPPPPAGGGGGAGGAGGGPPPGPPGA----GDRGGGGPGGGGPGG--GSAGGPSQPPGGG 65
            G P P G  G  G +G    PG PG     GD+G  G    G  G  G  G P  P   G
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092

Query: 66   GPGIR 70
             PGI+
Sbjct: 1093 NPGIK 1097



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 29/78 (37%), Positives = 32/78 (41%), Gaps = 18/78 (23%)

Query: 11   PGPPPPAGGG--GGAGGAGGGPPPGPPGA----------GDRG----GGGPGGGGPGG-- 52
            PGPP P      G  G  G    PG PG           GD G     G PG  GP G  
Sbjct: 949  PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008

Query: 53   GSAGGPSQPPGGGGPGIR 70
            G+ G P QP   G PG++
Sbjct: 1009 GNPGLPGQPGLIGPPGLK 1026



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 27/64 (42%), Positives = 29/64 (45%), Gaps = 6/64 (9%)

Query: 11   PGPP--PPAGGGGGAGGAGGGPP-PGPPGAGDRGG--GGPG-GGGPGGGSAGGPSQPPGG 64
            PGPP  P   G  G GG  G P  PG PG     G  G PG  G PG   + GP+     
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 65   GGPG 68
            G PG
Sbjct: 1252 GNPG 1255



 Score = 33.5 bits (75), Expect = 0.70
 Identities = 34/89 (38%), Positives = 35/89 (39%), Gaps = 28/89 (31%)

Query: 8   GPP--------PGPPPPAG--------GGGGAGGAGGGPP-PGPPGA----GDRGGGG-- 44
           GPP        PGPP   G        G  GA G  G P  PG PGA    G +G  G  
Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI 550

Query: 45  ---PGGGGPGG--GSAGGPSQPPGGGGPG 68
              PG  G  G  GS G P  P   G PG
Sbjct: 551 LTFPGMKGDKGELGSPGAPGLPGLPGTPG 579



 Score = 33.5 bits (75), Expect = 0.70
 Identities = 25/66 (37%), Positives = 27/66 (40%), Gaps = 6/66 (9%)

Query: 10   PPGPPPPAGGGGGAGGAG-GGPP-----PGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPG 63
            PPG     G  G  G  G  GPP     PG PG+    G     G PG  S G P  P  
Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081

Query: 64   GGGPGI 69
             G PG+
Sbjct: 1082 KGEPGL 1087



 Score = 33.1 bits (74), Expect = 0.92
 Identities = 28/81 (34%), Positives = 31/81 (38%), Gaps = 21/81 (25%)

Query: 11   PGPPPPAGGGGGAGGAGGGPPPGPPGA-GDRGGGG------PGGGGPGG----------- 52
            PGP    G  G +G  G    PG PG  GD+G  G      PG  GP G           
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094

Query: 53   ---GSAGGPSQPPGGGGPGIR 70
               GS G P  P   G PG +
Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAK 1115



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 21/58 (36%), Positives = 21/58 (36%)

Query: 10   PPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGP 67
            P G P   G  G  G  G    PG PG     G     G PG     GP  P G  GP
Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 12/72 (16%)

Query: 10  PPGPPPPAGGGGGAGGAGGGPPPGPPG----AGDRGG-GGPGGGGPGG-------GSAGG 57
           PPGP    G  G  G  G     G PG     G++G  G PG  GP G       GS G 
Sbjct: 906 PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965

Query: 58  PSQPPGGGGPGI 69
             +P   G PG+
Sbjct: 966 KGEPGLPGIPGV 977



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 6/65 (9%)

Query: 11   PGPPPPAGGGGGAGGAGGGPP--PGPPGAGDRGG--GGPGGGGPGG--GSAGGPSQPPGG 64
            PG P   G  G  G +  G P  PGP G     G  G PG  G  G  G  G P  P   
Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115

Query: 65   GGPGI 69
            G PG+
Sbjct: 1116 GQPGL 1120


>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
           isoform a [Homo sapiens]
          Length = 599

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 85/350 (24%), Positives = 144/350 (41%), Gaps = 75/350 (21%)

Query: 187 LPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAG 246
           +P+  VS    P+  Q+      D  SR +G  PG     +   Q      I++P    G
Sbjct: 155 IPDEEVSSPSPPQRAQRG-----DHSSREQGHAPG---GTSQARQIDFPLRILVPTQFVG 206

Query: 247 LVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDIL-RE 305
            +IGK G TIK + ++   ++ + +  +     +KP+ I   P    +AC M+++I+ +E
Sbjct: 207 AIIGKEGLTIKNITKQTQSRVDIHRKENSGA-AEKPVTIHATPEGTSEACRMILEIMQKE 265

Query: 306 RDQGGFGDRNEYGSRIGGGIDVPVPRHS--VGVVIGRSGEMIKKIQNDAGVRIQFK--QD 361
            D+          +++   I + +  H+  VG +IG+ G  +KKI+++ G +I     QD
Sbjct: 266 ADE----------TKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQD 315

Query: 362 DGT-GPEKIAHIMGPPDRCEHAARII---------NDLLQ-------------------- 391
                PE+   + G  + C  A   I         ND+L                     
Sbjct: 316 LSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFS 375

Query: 392 ---SLRSGPPGPPGGPGMPP--------GGRGRGRGQGNWGP-------PGGE-MTFSIP 432
              S+ S P GP G P   P        G          +GP       P  E +   IP
Sbjct: 376 TGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIP 435

Query: 433 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQ 482
           T   G +IG+ G ++K + +  GA ++I+    P  D + ++ II G P+
Sbjct: 436 TQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGP--DVSERMVIITGPPE 483



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 52/181 (28%), Positives = 90/181 (49%), Gaps = 15/181 (8%)

Query: 133 QLGPI---HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSG-GLP 188
           Q GP    H  P   +   + +P   VG IIG+ G  I ++ + +G  ++I+P  G  + 
Sbjct: 414 QFGPFPHHHSYPEQEIVNLF-IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS 472

Query: 189 ERSVSLTGAPESVQKAK-MMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGL 247
           ER V +TG PE+  KA+  +   +       P  +    A+         I +P+  AG 
Sbjct: 473 ERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAH---------IRVPSSTAGR 523

Query: 248 VIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERD 307
           VIGKGG+T+ +LQ     ++I+ +D + + N +  +RIIG  +  Q A   + +I+++  
Sbjct: 524 VIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 583

Query: 308 Q 308
           Q
Sbjct: 584 Q 584



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 78/318 (24%), Positives = 126/318 (39%), Gaps = 75/318 (23%)

Query: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQIS---PDSGGLPERSVSLTGAPESVQKAKMMLD 209
           +G+VG +IG+ G  + KI+ ++G K+ IS     S   PER++++ G  E+   A++ + 
Sbjct: 283 NGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIM 342

Query: 210 -----------------------------DIVSRG----------RGGPP---------- 220
                                         I S G          RG PP          
Sbjct: 343 KKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTH 402

Query: 221 -GQFHDNANGGQNGTV--------QEIM---IPAGKAGLVIGKGGETIKQLQERAGVKMI 268
            G F       Q G          QEI+   IP    G +IGK G  IKQL   AG  + 
Sbjct: 403 SGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIK 462

Query: 269 LIQDGSQNTNVDKPLRIIGDPYKVQ-QACEMVMDILRERDQGGFGDRNEYGSRIGGGIDV 327
           +    ++  +V + + II  P + Q +A   +   L+E  +  F  + E    +     +
Sbjct: 463 IAP--AEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE--ENFFNPKEE----VKLEAHI 514

Query: 328 PVPRHSVGVVIGRSGEMIKKIQN--DAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
            VP  + G VIG+ G+ + ++QN   A V +   Q      E I  I+G     + A R 
Sbjct: 515 RVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRK 574

Query: 386 INDLLQSLRSGPPGPPGG 403
           I +++Q ++      P G
Sbjct: 575 IREIVQQVKQQEQKYPQG 592



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 68/285 (23%), Positives = 102/285 (35%), Gaps = 68/285 (23%)

Query: 305 ERDQGGFGDRNEYGSRIGGG-----IDVP----VPRHSVGVVIGRSGEMIKKIQNDAGVR 355
           +R Q G     E G   GG      ID P    VP   VG +IG+ G  IK I      R
Sbjct: 167 QRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSR 226

Query: 356 IQFKQDDGTGP-EKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRG 414
           +   + + +G  EK   I   P+    A R+I +++Q                       
Sbjct: 227 VDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQK---------------------- 264

Query: 415 RGQGNWGPPGGEMTFSIPTHK--CGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNF 472
             + +      E+   I  H    G +IG+ G N+K I  +TG  + IS     +     
Sbjct: 265 --EADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPE 322

Query: 473 KLFIIRGSPQQIDHAK----QLIEEKIEGPLCPVG------PG----------------- 505
           +   ++G+ +    A+    + + E  E  +  V       PG                 
Sbjct: 323 RTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLS 382

Query: 506 -PGGPGPAGPMGPFNPGPFNQGPPGA--PPHAGGPPP--HQYPPQ 545
            P GP  A P  P++P   + G   +  P H  GP P  H YP Q
Sbjct: 383 PPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQ 427



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 36/149 (24%), Positives = 62/149 (41%), Gaps = 32/149 (21%)

Query: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTG-PEKIAHIMGPPD-RCEHA 382
           +++ +P  +VG +IG+ G  IK++   AG  I+    +G    E++  I GPP+ + +  
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489

Query: 383 ARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFS----IPTHKCGL 438
            RI   L +                           N+  P  E+       +P+   G 
Sbjct: 490 GRIFGKLKEE--------------------------NFFNPKEEVKLEAHIRVPSSTAGR 523

Query: 439 VIGRGGENVKAINQQTGAFVEISRQLPPN 467
           VIG+GG+ V  +   T A V + R   P+
Sbjct: 524 VIGKGGKTVNELQNLTSAEVIVPRDQTPD 552



 Score = 33.1 bits (74), Expect = 0.92
 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 13/102 (12%)

Query: 401 PGGPGMPPGGRGRGRGQGNWGPPGGE---------MTFSIPTHKCGLVIGRGGENVKAIN 451
           P  P     G    R QG+   PGG          +   +PT   G +IG+ G  +K I 
Sbjct: 163 PSPPQRAQRGDHSSREQGH--APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNIT 220

Query: 452 QQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE 493
           +QT + V+I R+   N     K   I  +P+    A ++I E
Sbjct: 221 KQTQSRVDIHRK--ENSGAAEKPVTIHATPEGTSEACRMILE 260


>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
          Length = 318

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 80/341 (23%), Positives = 141/341 (41%), Gaps = 58/341 (17%)

Query: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
           VG IIG+ GE + K++++SG ++ IS   G  PER ++L G   ++ KA  M+ D +   
Sbjct: 25  VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
                    ++    +      +++PA + G +IGKGG  IK+++E  G ++ +  D   
Sbjct: 83  ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139

Query: 276 NTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSV 334
           N + ++ + I G P  + +  + +  ++ E                  G+ +P  P+ S 
Sbjct: 140 N-STERAITIAGIPQSIIECVKQICVVMLESPP--------------KGVTIPYRPKPSS 184

Query: 335 GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394
             VI   G+    IQ    +     Q D T   ++A                       +
Sbjct: 185 SPVIFAGGQAY-TIQGQYAI----PQPDLTKLHQLA---------------------MQQ 218

Query: 395 SGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQT 454
           S  P   G  G   G     +   +      E+T  IP    G +IGR G  +  I Q +
Sbjct: 219 SHFPMTHGNTGFSAGLDASAQTTSH------ELT--IPNDLIGCIIGRQGAKINEIRQMS 270

Query: 455 GAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
           GA ++I+  +  + D   +   I GS   I  A+ LI  ++
Sbjct: 271 GAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 308



 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 53/190 (27%), Positives = 82/190 (43%), Gaps = 33/190 (17%)

Query: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
           VG +IG+ GE +KK++ ++G RI   +  G  PE+I  + GP +    A  +I D L+  
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82

Query: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
            S           PP                  +   +P  +CG +IG+GG  +K I + 
Sbjct: 83  ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126

Query: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512
           TGA V+++  + PN     +   I G PQ  I+  KQ+    +E P            P 
Sbjct: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESP------------PK 172

Query: 513 GPMGPFNPGP 522
           G   P+ P P
Sbjct: 173 GVTIPYRPKP 182



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 25/73 (34%), Positives = 47/73 (64%)

Query: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205
           + E  +P+ ++G IIGR G +IN+I+Q SG +++I+    G  +R V++TG+  S+  A+
Sbjct: 242 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 301

Query: 206 MMLDDIVSRGRGG 218
            +++  +S   GG
Sbjct: 302 YLINVRLSSETGG 314



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%)

Query: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
           + ISS +       R  +T    VP    G +IG+GG +I +I++ +G +VQ++ D   L
Sbjct: 81  EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138

Query: 188 P---ERSVSLTGAPESV 201
           P   ER++++ G P+S+
Sbjct: 139 PNSTERAITIAGIPQSI 155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.139    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,572,903
Number of Sequences: 37866
Number of extensions: 4200814
Number of successful extensions: 104053
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1178
Number of HSP's successfully gapped in prelim test: 1503
Number of HSP's that attempted gapping in prelim test: 23899
Number of HSP's gapped (non-prelim): 36176
length of query: 711
length of database: 18,247,518
effective HSP length: 109
effective length of query: 602
effective length of database: 14,120,124
effective search space: 8500314648
effective search space used: 8500314648
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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